WorldWideScience

Sample records for quality control tests

  1. 7 CFR 58.335 - Quality control tests.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 3 2010-01-01 2010-01-01 false Quality control tests. 58.335 Section 58.335... Procedures § 58.335 Quality control tests. All milk, cream and related products are subject to inspection for quality and condition throughout each processing operation. Quality control tests shall be made on...

  2. 7 CFR 58.928 - Quality control tests.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 3 2010-01-01 2010-01-01 false Quality control tests. 58.928 Section 58.928... Procedures § 58.928 Quality control tests. All dairy products and other ingredients shall be subject to inspection for quality and condition throughout each processing operation. Quality control tests shall...

  3. 7 CFR 58.642 - Quality control tests.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 3 2010-01-01 2010-01-01 false Quality control tests. 58.642 Section 58.642... Procedures § 58.642 Quality control tests. All mix ingredients shall be subject to inspection for quality and condition throughout each processing operation. Quality control tests shall be made on flow line samples...

  4. 21 CFR 640.56 - Quality control test for potency.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 7 2010-04-01 2010-04-01 false Quality control test for potency. 640.56 Section...) BIOLOGICS ADDITIONAL STANDARDS FOR HUMAN BLOOD AND BLOOD PRODUCTS Cryoprecipitate § 640.56 Quality control test for potency. (a) Quality control tests for potency of antihemophilic factor shall be...

  5. 7 CFR 58.523 - Laboratory and quality control tests.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 3 2010-01-01 2010-01-01 false Laboratory and quality control tests. 58.523 Section... Service 1 Operations and Operating Procedures § 58.523 Laboratory and quality control tests. (a) Quality control tests shall be made on samples as often as necessary to determine the shelf-life and stability...

  6. 7 CFR 58.733 - Quality control tests.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 3 2010-01-01 2010-01-01 false Quality control tests. 58.733 Section 58.733... Procedures § 58.733 Quality control tests. (a) Chemical analyses. The following chemical analyses shall be... pasteurization by means of the phosphatase test, as well as any other tests necessary to assure good...

  7. 7 CFR 58.442 - Laboratory and quality control tests.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 3 2010-01-01 2010-01-01 false Laboratory and quality control tests. 58.442 Section... Service 1 Operations and Operating Procedures § 58.442 Laboratory and quality control tests. (a) Chemical... Methods or by other methods giving equivalent results. (b) Weight or volume control....

  8. Quality control tests for the CMS Barrel RPCs

    Energy Technology Data Exchange (ETDEWEB)

    Abbrescia, M. [Dipartimento Interateneo di Fisica and Sezione INFN, v. G. Amendola 173, 70126 Bari (Italy); Colaleo, A. [Dipartimento Interateneo di Fisica and Sezione INFN, v. G. Amendola 173, 70126 Bari (Italy); Guida, R. [Dipartimento Interateneo di Fisica and Sezione INFN, v. G. Amendola 173, 70126 Bari (Italy); Iaselli, G. [Dipartimento Interateneo di Fisica and Sezione INFN, v. G. Amendola 173, 70126 Bari (Italy); Loddo, F. [Dipartimento Interateneo di Fisica and Sezione INFN, v. G. Amendola 173, 70126 Bari (Italy); Maggi, M. [Dipartimento Interateneo di Fisica and Sezione INFN, v. G. Amendola 173, 70126 Bari (Italy); Marangelli, B. [Dipartimento Interateneo di Fisica and Sezione INFN, v. G. Amendola 173, 70126 Bari (Italy); Natali, S. [Dipartimento Interateneo di Fisica and Sezione INFN, v. G. Amendola 173, 70126 Bari (Italy); Nuzzo, S. [Dipartimento Interateneo di Fisica and Sezione INFN, v. G. Amendola 173, 70126 Bari (Italy); Pugliese, G. [Dipartimento Interateneo di Fisica and Sezione INFN, v. G. Amendola 173, 70126 Bari (Italy)]. E-mail: Gabriella.Pugliese@ba.infn.it; Ranieri, A. [Dipartimento Interateneo di Fisica and Sezione INFN, v. G. Amendola 173, 70126 Bari (Italy); Romano, F. [Dipartimento Interateneo di Fisica and Sezione INFN, v. G. Amendola 173, 70126 Bari (Italy); Trentadue, R. [Dipartimento Interateneo di Fisica and Sezione INFN, v. G. Amendola 173, 70126 Bari (Italy); Cavallo, N.; Fabozzi, F. [Universita degli studi della Basilicata and Sezione INFN, Naples (Italy); Paolucci, P.; Piccolo, D.; Polese, G.; Sciacca, C.; Belli, G.; Necchi, M.; Ratti, S.P.; Riccardi, C.; Torre, P.; Vitulo, P. [Dipartimento di Fisica Nucleare e Teorica and Sezione INFN, v. U. Bassi 6, 27100 Pavia (Italy); Anguelov, T.; Genchev, V.; Panev, B.; Piperov, S.; Sultanov, G.; Vankov, P. [INRNE, BAS, Soa (Bulgaria); Dimitrov, A.; Litov, L.; Pavlov, B.; Petkov, P. [University of Soa St. Kliment Ohridski (Bulgaria)

    2006-08-15

    An RPC based system will be employed for the CMS muon first level trigger. Severe quality controls and certification have been established all along the entire production chain. Procedures are briefly described and results for the acceptance percentage are given for the second part of the single gaps and double gaps production. Summary results are also reported for the full sets of tested chambers.

  9. ITC Guidelines on Quality Control in Scoring, Test Analysis, and Reporting of Test Scores

    Science.gov (United States)

    Allalouf, Avi

    2014-01-01

    The Quality Control (QC) Guidelines are intended to increase the efficiency, precision, and accuracy of the scoring, analysis, and reporting process of testing. The QC Guidelines focus on large-scale testing operations where multiple forms of tests are created for use on set dates. However, they may also be used for a wide variety of other testing…

  10. ITC Guidelines on Quality Control in Scoring, Test Analysis, and Reporting of Test Scores

    Science.gov (United States)

    Allalouf, Avi

    2014-01-01

    The Quality Control (QC) Guidelines are intended to increase the efficiency, precision, and accuracy of the scoring, analysis, and reporting process of testing. The QC Guidelines focus on large-scale testing operations where multiple forms of tests are created for use on set dates. However, they may also be used for a wide variety of other testing…

  11. Quality control for quantitative PCR based on amplification compatibility test.

    Science.gov (United States)

    Tichopad, Ales; Bar, Tzachi; Pecen, Ladislav; Kitchen, Robert R; Kubista, Mikael; Pfaffl, Michael W

    2010-04-01

    Quantitative qPCR is a routinely used method for the accurate quantification of nucleic acids. Yet it may generate erroneous results if the amplification process is obscured by inhibition or generation of aberrant side-products such as primer dimers. Several methods have been established to control for pre-processing performance that rely on the introduction of a co-amplified reference sequence, however there is currently no method to allow for reliable control of the amplification process without directly modifying the sample mix. Herein we present a statistical approach based on multivariate analysis of the amplification response data generated in real-time. The amplification trajectory in its most resolved and dynamic phase is fitted with a suitable model. Two parameters of this model, related to amplification efficiency, are then used for calculation of the Z-score statistics. Each studied sample is compared to a predefined reference set of reactions, typically calibration reactions. A probabilistic decision for each individual Z-score is then used to identify the majority of inhibited reactions in our experiments. We compare this approach to univariate methods using only the sample specific amplification efficiency as reporter of the compatibility. We demonstrate improved identification performance using the multivariate approach compared to the univariate approach. Finally we stress that the performance of the amplification compatibility test as a quality control procedure depends on the quality of the reference set.

  12. Quality Control: microbial limit tests for nonsterile pharmaceuticals, part 2.

    Science.gov (United States)

    Vu, Nicole; Lou, Jessica R; Kupiec, Thomas C

    2014-01-01

    Cases of contaminated nonsterile products have been reported in increasing numbers. Often, these contaminated products are associated with the presence of objectionable microorganisms. The major contaminants of nonsterile pharmaceutical products and ingredients are bacteria, yeasts, and molds. The combination of parts 1 and 2 of this series of articles provides a thorough examination of microbiological quality testing for nonsterile products.

  13. Virological control of groundwater quality using biomolecular tests.

    Science.gov (United States)

    Carducci, A; Casini, B; Bani, A; Rovini, E; Verani, M; Mazzoni, F; Giuntini, A

    2003-01-01

    Deep groundwater, even if generally protected, could be contaminated by surface or rain water infiltration through soil fractures, septic tanks, cesspits, land irrigation, disposal of wastewater and disposal of muds from depuration systems. The sanitary importance of such possible contamination is related to the different uses of the water and it is at the maximum level when it is intended for human use. Routine microbiological analyses do not consider viruses, only bacterial parameters, as contamination indicators. However, it is known that enteric viruses can survive a long time in deep aquifers and that they may not always be associated with bacterial indicators. The virological analysis of waters intended for drinking use is provided only as an occasional control exercised at the discretion of the sanitary authority. Technological difficulties with obtaining data about groundwater viral contamination led to a study to devise rapid and efficient methods for their detection and the application of these methods to samples from different sources. Four acid nucleic extraction techniques have been tested (classic proteinase K- phenol/chloroform, QIAamp Viral RNA Kit (Qiagen), SV Total RNA Isolation System (Promega) and NucleoSpin Virus L (Macherey-Nagel). Sensitivity and specificity of RT-PCR protocols for entero- (EV), hepatitis A (HAV) and small round structured (SRSV) viruses have been verified. Deep groundwater samples (100 L) were concentrated (2-step tangential flow ultrafiltration) and the concentrate contaminated with serial 10-fold dilutions of a known titre of poliovirus type 3. Extracted RNA was concentrated (microcon-100) and analysed by RT-PCR using specific EV primers and visualising amplification products by agarose gel electrophoresis. In addition, two different methods of RT-PCR for non-cultivable viruses have been tested: (a) RT-PCR and nested RT-PCR for HAV and (b) RT-PCR with generic primers and RT-PCR with specific primers for SRSV. Different

  14. Internal quality control in point-of-care testing: where's the evidence?

    Science.gov (United States)

    Holt, Helen; Freedman, Danielle B

    2016-03-01

    ISO 22870 standards require protocols for performance of internal quality control for all point-of-care testing devices and training of users in its theory and practice. However, the unique setting of point-of-care testing (i.e. processes conducted by non-scientific users) means that laboratory internal quality control programmes do not easily translate to point-of-care testing. In addition, while the evidence base for internal quality control within the laboratory has been increasing, the equivalent literature surrounding point-of-care testing is very limited. This has led to wide variation in what is considered acceptable practice for internal quality control at the point of care. Indeed, it has been demonstrated that internal quality control is an area of deficiency in point-of-care testing. Internal quality control protocols used at point-of-care testing should be defined based on risk management. The protocol will therefore be dependent on analyser complexity and availability of inbuilt system checks, the risk associated with release of an incorrect patient result as well as frequency of use. The emphasis should be on designing an effective internal quality control protocol as opposed to the inherent tendency of introducing high-frequency quality control. Typically a simple pass or fail criterion is used for internal quality control in point-of-care testing based on whether internal quality control results fall within assigned ranges. While simply taught, such criteria can require broad internal quality control ranges to decrease the probability of false rejection (also reducing the probability of error detection). Customized internal quality control ranges, two-tier acceptance systems and assay-specific internal quality control can be used to improve error detection rates.

  15. Quality Test Template toward Multi-user Access Control of Internet-Based System

    Directory of Open Access Journals (Sweden)

    Nan Nie

    2011-06-01

    Full Text Available Aiming at three kinds of Internet-based system quality problems, which is performance, liability and security, the paper proposes a kind of test template during multi-user login and resource access control, which includes test requirement, login script, role-resource correlating and mutation test technique. Some Internet-based systems are tested and diagnosed by automation test technique of test template. At last, system quality can be verified and improved through the realization mechanism of test template.

  16. Quality Control for Scoring Tests Administered in Continuous Mode: An NCME Instructional Module

    Science.gov (United States)

    Allalouf, Avi; Gutentag, Tony; Baumer, Michal

    2017-01-01

    Quality control (QC) in testing is paramount. QC procedures for tests can be divided into two types. The first type, one that has been well researched, is QC for tests administered to large population groups on few administration dates using a small set of test forms (e.g., large-scale assessment). The second type is QC for tests, usually…

  17. Incorporating quality control activities in scrum in relation to the concept of test backlog

    Indian Academy of Sciences (India)

    MUHAMMAD AAMIR; MUHAMMAD NAEEM AHMED KHAN

    2017-07-01

    Scrum has become popular among the agile methodologies due to the substantial support that it provides to the project management teams. The scrum process delivers quick functionality in the form of sprints.Most of the quality assurance and quality control activities are skipped in scrum because of its short lifecycleand due to the absence of a dedicated quality assurance team. The development team pays more attention to delivery of products according to the customer satisfaction, and the parameters used for this type of assessment are the story success criteria and user acceptance testing. Only acceptance testing and integration testing are not sufficient to achieve a quality product. There is still a clamouring need felt to incorporate other quality control activities in scrum to achieve a quality product. In this work, we have made an attempt to implement the quality control activities in the scrum philosophy by introducing the concept of test backlog. The enhanced scrum model provides quality assessment methodology on the basis of frequency of remaining functional bugs. The concept of test backlog proposed in this study aims at implementing state of the art testing process in scrum. A case study was carried out to validate the model, which produced satisfactory results. Besides, we conducted a survey to access the state of the quality control in scrum. The proposed model and case study results are reported herein

  18. 30 CFR 28.33 - Quality control test methods, equipment, and records; review by MSHA; revocation of approval.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Quality control test methods, equipment, and... Quality Control § 28.33 Quality control test methods, equipment, and records; review by MSHA; revocation... control test methods, equipment, and records, and to interview any employee or agent of the applicant in...

  19. Anticipated Effectiveness of Active Noise Control in Propeller Aircraft Interiors as Determined by Sound Quality Tests

    Science.gov (United States)

    Powell, Clemans A.; Sullivan, Brenda M.

    2004-01-01

    Two experiments were conducted, using sound quality engineering practices, to determine the subjective effectiveness of hypothetical active noise control systems in a range of propeller aircraft. The two tests differed by the type of judgments made by the subjects: pair comparisons in the first test and numerical category scaling in the second. Although the results of the two tests were in general agreement that the hypothetical active control measures improved the interior noise environments, the pair comparison method appears to be more sensitive to subtle changes in the characteristics of the sounds which are related to passenger preference.

  20. Quality control test for electronic portal imaging device using QC-3 phantom with PIPSpro

    Directory of Open Access Journals (Sweden)

    Birendra Kumar Rout

    2014-12-01

    Full Text Available Purpose:A Quality control (QC test suitable for routinely daily use has been established for electronic portal imaging device (EPID using PIPSpro software version 4.4 (Standard Imaging, Middleton, WI. It provides an objective and quantitative test for tolerable image quality on the basis of the high contrast spatial resolution, the contrast-to-noise ratio (CNR and noise.Methods: The test uses a QC-3 phantom consisting of five sets of high contrast rectangular bar patterns with spatial frequeinces of 0.10, 0.20, 0.25, 0.43 and 0.75 lp/mm using 6MV and 15MV photon energy for accquiring high quality images. A “base line” value for the relative square wave modulation transfer function (RMTF, CNR and Noise data was obtained during a one week calibration period and one month test period.Results: Subsequent measurements shows significant deviations from baseline values, resulting in warning messages “potential problems in system performance”. The QC test uses high contrast spatial resolution and CNR for the system with acceptable performance. Conclusion: The method provides an automatic, objective, and sensitive measure of the system's imaging performance. This is a useful implementation during acceptance testing, commissioning, and routine quality control.

  1. Electronic nose for quality control of Colombian coffee through the detection of defects in "Cup Tests".

    Science.gov (United States)

    Rodríguez, Juan; Durán, Cristhian; Reyes, Adriana

    2010-01-01

    Electronic noses (ENs), are used for many applications, but we must emphasize the importance of their application to foodstuffs like coffee. This paper presents a research study about the analysis of Colombian coffee samples for the detection and classification of defects (i.e., using "Cup Tests"), which was conducted at the Almacafé quality control laboratory in Cúcuta, Colombia. The results obtained show that the application of an electronic nose called "A-NOSE", may be used in the coffee industry for the cupping tests. The results show that e-nose technology can be a useful tool for quality control to evaluate the excellence of the Colombian coffee produced by National Federation of Coffee Growers.

  2. A routine quality assurance test for CT automatic exposure control systems.

    Science.gov (United States)

    Iball, Gareth R; Moore, Alexis C; Crawford, Elizabeth J

    2016-07-08

    The study purpose was to develop and validate a quality assurance test for CT automatic exposure control (AEC) systems based on a set of nested polymethylmethacrylate CTDI phantoms. The test phantom was created by offsetting the 16 cm head phantom within the 32 cm body annulus, thus creating a three part phantom. This was scanned at all acceptance, routine, and some nonroutine quality assurance visits over a period of 45 months, resulting in 115 separate AEC tests on scanners from four manufacturers. For each scan the longitudinal mA modulation pattern was generated and measurements of image noise were made in two annular regions of interest. The scanner displayed CTDIvol and DLP were also recorded. The impact of a range of AEC configurations on dose and image quality were assessed at acceptance testing. For systems that were tested more than once, the percentage of CTDIvol values exceeding 5%, 10%, and 15% deviation from baseline was 23.4%, 12.6%, and 8.1% respectively. Similarly, for the image noise data, deviations greater than 2%, 5%, and 10% from baseline were 26.5%, 5.9%, and 2%, respectively. The majority of CTDIvol and noise deviations greater than 15% and 5%, respectively, could be explained by incorrect phantom setup or protocol selection. Barring these results, CTDIvol deviations of greater than 15% from baseline were found in 0.9% of tests and noise deviations greater than 5% from baseline were found in 1% of tests. The phantom was shown to be sensitive to changes in AEC setup, including the use of 3D, longitudinal or rotational tube current modulation. This test methodology allows for continuing performance assessment of CT AEC systems, and we recommend that this test should become part of routine CT quality assurance programs. Tolerances of ± 15% for CTDIvol and ± 5% for image noise relative to baseline values should be used.

  3. External quality assessment/proficiency testing and internal quality control for the PFA-100 and PFA-200: an update.

    Science.gov (United States)

    Favaloro, Emmanuel J; Bonar, Roslyn

    2014-03-01

    Platelet function testing is an essential component of comprehensive hemostasis evaluation within the framework of bleeding and/or bruising investigations, and it may also be performed to evaluate antiplatelet medication effects. Globally, the platelet function analyzer (PFA)-100 (Siemens Healthcare, Marburg, Germany) is the most used primary hemostasis-screening instrument and has also been recently remodeled/upgraded to the PFA-200. The PFA-100 is sensitive to a wide range of associated disorders, including platelet function defects and von Willebrand disease (VWD), as well as to various antiplatelet medications. The PFA-100 is also useful in therapy monitoring, especially in VWD. External quality assessment (EQA) (or proficiency testing) and internal quality control (IQC) are critical to ensuring quality of test practice, inclusive of all hemostasis tests. However, both EQA and IQC for platelet function testing, including the PFA-100, is logistically challenging, given theoretical requirements for production, storage, and shipment of large volumes of "stabilized" normal and pathological blood/platelets covering both normal function plus a wide variety of potential defects. We accordingly describe the development and testing of novel feasible approaches to both EQA and IQC of PFA-100/PFA-200 instruments, whereby a range of formulated "platelet function antagonist" materials are utilized. For EQA purposes, these are distributed to participants, and citrated normal whole blood collected on site is then added locally, thereby creating test material that can be locally evaluated. Several exercises have been conducted by the Royal College of Pathologists of Australasia Quality Assurance Program (RCPAQAP) over the past 6 years. A total of 26 challenges, with most designed to mimic moderate to severe primary hemostasis defects, have been tested in 26 to 50 laboratories depending on the year of dispatch. Numerical results for PFA-100/PFA-200 closure times (CTs) and

  4. Quality control ranges for testing broth microdilution susceptibility of Flavobacterium columnare and F. psychrophilium to nine antimicrobials

    Science.gov (United States)

    A multi-laboratory broth microdilution method trial was performed to standardize the specialized test conditions required for fish pathogens Flavobacterium columnare and F. pyschrophilum. Nine laboratories tested the quality control (QC) strains Escherichia coli ATCC 25922 and Aeromonas salmonicid...

  5. Quality control for the in-clinic veterinary laboratory and pre-analytic considerations for specialized diagnostic testing.

    Science.gov (United States)

    Camus, Melinda S

    2016-09-01

    This review, aimed primarily at general practitioners, focuses on quality assurance/quality control principles for all three phases of clinical pathology testing: preanalytic, analytic, and postanalytic. Specific emphasis is placed on the preanalytic phase of diagnostic modalities for identifying neoplastic cells, specifically flow cytometry, PCR for antigen receptor rearrangement, and immunocytochemistry. Recommendations for establishing an in-clinic quality assurance system are provided.

  6. Summary, the 20th quality control survey for radioisotopes in vitro tests in Japan, 1998

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-11-01

    For advancement of radioisotope in vitro tests such as radioimmunoassay and immunoradiometric assay, the Subcommittee for Radioisotope in vitro Test in Medical and Pharmaceutical Committee of Japan Radioisotope Association has conducted the yearly quality control survey for the test facilities in Japan since 1978. This is the summary of the 20th survey in 1998 where non-radioisotope tests like enzyme-immunoassay were involved as well. The survey was done for 143 facilities: 20 national and public university hospitals, 18 private university hospitals, 8 national hospitals, 13 public hospitals, 21 private hospitals, 41 hygienic laboratories and 22 manufacturers of reagents. Facilities examined intra- and between day-reproducibility, freeze-thaw effect and time change of the measured values on the same samples. Assays were for: growth hormone (h), somatomedin C, follicle stimulating h, luteinizing h, prolactin, thyroid stimulating h, triiodothyronines, thyroxines, thyroxine binding protein, calcitonin, insulin, C-peptide, glucagons, gastrin, testosterones, estradiol, progesterone, gonadotropin, 17{alpha}-hydroxyprogesterone, aldosterone, cortisol, dehydroepiandorosterone sulfate, renin, IgE, digoxin, {alpha}-fetoprotein, carcinoembryonic antigen, tissue polypeptide antigen, CA (125, 19-9 and 15-3), prostatic acid phosphatase, prostate specific antigen, {beta}2-microglobulin, ferritin, and neuron specific enolase. There was no great difference between this and last survey results although tendency of improvement was recognized. There were problems to be solved from the standpoint of clinical practice. (K.H.)

  7. [Development of external quality control protocol for CyberKnife beams dosimetry: preliminary tests multicentre].

    Science.gov (United States)

    Guinement, L; Marchesi, V; Veres, A; Lacornerie, T; Buchheit, I; Peiffert, D

    2013-01-01

    To develop an external quality control procedure for CyberKnife(®) beams. This work conducted in Nancy, has included a test protocol initially drawn by the medical physicist of Nancy and Lille in collaboration with Equal-Estro Laboratory. A head and neck anthropomorphic phantom and a water-equivalent homogeneous cubic plastic test-object, so-called "MiniCube", have been used. Powder and solid thermoluminescent dosimeters as well as radiochromic films have been used to perform absolute and relative dose studies, respectively. The comparison between doses calculated by Multiplan treatment planning system and measured doses have been studied in absolute dose. The dose distributions measured with films and treatment planning system calculations have been compared via the gamma function, configured with different tolerance criteria. This work allowed, via solid thermoluminescent dosimeter measurements, verifying the beam reliability with a reproducibility of 1.7 %. The absolute dose measured in the phantom irradiated by the seven participating centres has shown an error inferior to the standard tolerance limits (± 5 %), for most of participating centres. The relative dose measurements performed at Nancy and by the Equal-Estro laboratory allowed defining the most adequate parameters for gamma index (5 %/2mm--with at least 95 % of pixels satisfying acceptability criteria: γsoftware. This work allowed defining a dosimetric external quality control for CyberKnife(®) systems, based on a reproducible irradiation plan through measurements performed with thermoluminescent dosimeters and radiochromic films. This protocol should be validated by a new series of measurement and taking into account the lessons of this work. Copyright © 2013 Société française de radiothérapie oncologique (SFRO). Published by Elsevier SAS. All rights reserved.

  8. Operational quality control of daily precipitation using spatio-climatological consistency testing

    Science.gov (United States)

    Scherrer, S. C.; Croci-Maspoli, M.; van Geijtenbeek, D.; Naguel, C.; Appenzeller, C.

    2010-09-01

    Quality control (QC) of meteorological data is of utmost importance for climate related decisions. The search for an effective automated QC of precipitation data has proven difficult and many weather services still use mainly manual inspection of daily precipitation including MeteoSwiss. However, man power limitations force many weather services to move towards less labour intensive and more automated QC with the challenge to keeping data quality high. In the last decade, several approaches have been presented to objectify daily precipitation QC. Here we present a spatio-climatological approach that will be implemented operationally at MeteoSwiss. It combines the information from the event based spatial distribution of everyday's precipitation field and the historical information of the interpolation error using different precipitation intensity intervals. Expert judgement shows that the system is able to detect potential outliers very well (hardly any missed errors) without creating too many false alarms that need human inspection. 50-80% of all flagged values have been classified as real errors by the data editor. This is much better than the roughly 15-20% using standard spatial regression tests. Very helpful in the QC process is the automatic redistribution of accumulated several day sums. Manual inspection in operations can be reduced and the QC of precipitation objectified substantially.

  9. Characteristic and quality control test in sector collimator gamma knife perfexion at Siloam hospital

    Science.gov (United States)

    Wesly Manik, Jhon; Hidayanto, Eko; Sutanto, Heri

    2017-01-01

    In this study conducted to evaluate the collimator 4 mm, 8 mm, 16 mm to determine the level of precision Gamma Knife Perfexion there three years and eight months has not carried out measurements after the first year and verify the alignment of sector 1-8. Measurement with three axes (x-axis, y-axis, z-axis) using the film Gafcromic EBT-3, which will be signaled to a central point in the film to be measured and given a dose of 5 Gy for 10 minutes and then scanned and analyzed using ImageJ softwere 1.50 and dose rate in film comparison with measurent dose rate using electrometer. Alignment of Patient-Positioning System (PPS) with Radiation Focal Point (RFP) determination of quality control testing each collimator 4 mm in the standard test with 0.4 mm passive voice AAPM 54. The results of the standard are still in conformity item 0.21 mm for 4 mm and corelasi dose rate film and measurent using electrometer collimator 4 mm = 0.965, 8 mm = 0.964, 16 mm = 0.959.

  10. 10 CFR 26.137 - Quality assurance and quality control.

    Science.gov (United States)

    2010-01-01

    ... 10 Energy 1 2010-01-01 2010-01-01 false Quality assurance and quality control. 26.137 Section 26....137 Quality assurance and quality control. (a) Quality assurance program. Each licensee testing... metabolites. (b) Performance testing and quality control requirements for validity screening tests....

  11. Controlling Stormwater Quality with Filter Soil—Event and Dry Weather Testing

    Directory of Open Access Journals (Sweden)

    Karin Cederkvist

    2016-08-01

    Full Text Available The use of filter soil is increasing for control of quality of stormwater runoff prior to infiltration or discharge. This study aimed to gain knowledge about treatment efficacy of filter soils at field scale. Percolate samples from swale-trench systems with filter soil based on agricultural till with/without limestone were monitored for 15 and 9 rain events respectively. Further, two curb extensions with filter soil based on landfill soil were monitored for 10 and 8 events. Pollutant concentrations in percolate were compared to influent samples from the catchment area. Additionally one of the curb extensions was tested twice by adding high-dose synthetic influent containing runoff pollutants of concern. Despite generally low influent pollutant levels, phosphorus, copper, zinc, lead and some polyaromatic hydrocarbons exceeded guiding criteria for protection of groundwater and freshwater. Concentrations in the percolate were in most cases reduced, but phosphorus increased and despite reduced concentrations copper, lead and benzo(apyrene still exceeded guiding criteria. Pollutants from the synthetic influent were efficiently retained, except the pesticide MCPA. Filter soil based on landfill soil tended to perform better than agricultural till. No impact of limestone was observed. Overall the filter soils performed well in retaining pollutants, despite simultaneous processes of mobilization and immobilization.

  12. The 11th quality control survey for radioisotopes in vitro tests in Japan, 1989

    Energy Technology Data Exchange (ETDEWEB)

    1990-10-01

    This report presents the results of the 11th quality control nationwide survey. Of 730 facilities performing radioisotopes in vitro tests in November 1989, 422 facilities (60.5%) participated in the present survey. The following 23 items were examined: adrenocorticotropic hormone (ACTH), albumin, carbohydrate antigen 125 (CA 125), carbohydrate antigen 19-9 (CA 19-9), carcinoembryonic antigen (CEA), calcitonin, cortisol, estradiol, ferritin, free thyroxine (FT{sub 4}), follicle stimulating hormone (FSH), gastrine, cholylglycine, glucagon, insulin, anti-DNA antibody, luteinizing hormone (LH), neuron specific enolase (NSE), parathyroid hormone (PTH), squamous cell carcinoma associated antigen (SCC), thyroxine (T{sub 4}), thyroxine binding globulin (TBG), and antithyroid stimulating hormone (TSH) receptor antibody. 'Within kit variation' between facilities showed large coefficient of variation for ACTH, CA125, CEA, estradiol, ferritin, FSH, glucagon, anti-DNA antibody, LH, PTH, and TSH receptor antibody. Both 'within kit variation' and 'between kit variation' showed small coefficient of variation for cortisol, free T{sub 4}, NSE, SCC, T{sub 4}, and TBG. The present survey was characterized by using immunoradiometric assay (IRMA) and non-isotope techniques, as well as radioimmunoassay. Kits for IRMA greatly varied from facility to facility. (N.K.).

  13. User attitudes in analyzing digital slides in a quality control test bed: a preliminary study.

    Science.gov (United States)

    Della Mea, Vincenzo; Demichelis, Francesca; Viel, Federico; Dalla Palma, Paolo; Beltrami, Carlo Alberto

    2006-05-01

    The pathologist examines suitably stained glass slides through a bright field microscope in order to render histopathological or cytological diagnosis by looking at tissues and cells. Glass slides serve as a permanent record of the patient disease. Over the course of a patient's treatment slides may need to be reviewed at other institutions before treatment can commence. Due to their fragile nature a transportable permanent digital facsimile of the glass slide would be ideal. A digital slide is a set of digital images representing the whole slide normally used by the pathologist, or a significant part of it; it is usually made by a large amount of images, up to thousands, which makes its management difficult. The present paper provides a description of the requirements needed to reproduce glass slides and of the available technological equipment, then the features of the two systems we implemented on different hardware are described, together with those of the digital slide viewer. The viewer was evaluated in two experimental test phases, during which user behaviour and diagnostic reports were measured. Digital slides used in the two experiments were acquired with either system. Possible applications of digital slides are then discussed, including undergraduate and professional education, quality control, and image analysis on full samples as well as on tissue microarrays.

  14. Effect of baby oil on pruritus, sleep quality, and quality of life in hemodialysis patients: pretest-post-test model with control groups.

    Science.gov (United States)

    Karadag, Ezgi; Kilic, Serap Parlar; Karatay, Gülnaz; Metin, Ozgur

    2014-07-01

    To assess the effect of baby oil on pruritus, sleep quality, and quality of life in hemodialysis (HD) patients. This pretest-post-test model with control groups study was conducted in HD units in two different provinces in eastern Turkey. The study group consisted of a total of 70 patients receiving HD treatment who met the inclusion criteria, 35 being in the intervention group and 35 in the control group. After the patients in both groups were informed about the study, they were administered a questionnaire, the Severity Scale, Visual Analog Scale, the Pittsburgh Sleep Quality Index, and the SF-36 Quality of Life Scale. Following the administration of baby oil to the patients in the intervention group three times a week for a period of 1 month, the same scales were repeated to explore their pruritic status, sleep quality, and quality of life. The same scales were repeated also for the patients in the control group 1 month later but without administering any baby oil. When the Itch Severity Scale, Visual Analog Scale, Pittsburgh Sleep Quality Index, and SF-36 Quality of Life Physical and Mental Component scores of the patients in the control and intervention groups before and after the intervention were compared, the differences in the change were found to be statistically significant in favor of the intervention group (P quality of life, and sleep quality in HD patients who had itching complaints. © 2013 The Authors. Japan Journal of Nursing Science © 2013 Japan Academy of Nursing Science.

  15. Modernized build and test infrastructure for control software at ESO: highly flexible building, testing, and automatic quality practices for telescope control software

    Science.gov (United States)

    Pellegrin, F.; Jeram, B.; Haucke, J.; Feyrin, S.

    2016-07-01

    The paper describes the introduction of a new automatized build and test infrastructure, based on the open-source software Jenkins1, into the ESO Very Large Telescope control software to replace the preexisting in-house solution. A brief introduction to software quality practices is given, a description of the previous solution, the limitations of it and new upcoming requirements. Modifications required to adapt the new system are described, how these were implemented to current software and the results obtained. An overview on how the new system may be used in future projects is also presented.

  16. The 14th quality control survey for radioisotope in vitro tests in Japan, 1992

    Energy Technology Data Exchange (ETDEWEB)

    1993-11-01

    This report presents the results of the 14th quality control nationwide survey. Of 490 facilities performing RI in vitro tests as of December 1992, 261 (53.3%) participated in the present 1992 survey. Free testosterone and renin were added to the following conventional 37 test items: adrenocorticotropic hormone (ACTH), growth hormone (GH), somatomedin C, follicle stimulating hormone (FSH), luteinizing hormone (LH), prolactin, thyroid stimulating hormone (TSH), triiodothyronine (T[sub 3]), free T[sub 3], thyroxine (T[sub 4]), free T[sub 4], T[sub 3] uptake, thyroglobulin, T[sub 3] binding globulin (TBG), parathyroid hormone (PTH), calcitonin, insulin, C-peptide, glucagon, gastrin, testosterone, estradiol, progesterone, 17[alpha]-hydroxyprogesterone, aldosterone, cortisol, immunoglobulin E (IgE), digoxin, [alpha]-fetoprotein, carcinoembryonic antigen (CEA), tissue polypeptide antigen (TPA), CA125, CA19-9, CA15-3, prostatic acid phosphatase (PAP), [beta][sub 2]-microglobulin, and ferritin. Measurement data for each kit were analyzed by a mean value of measurements, standard deviation, and coefficient of variation (CV). Both 'within kit variation' between facilities and 'between kit variation' showed a CV of 20% or less for GH, somatomedin C, TSH, T[sub 3], T[sub 4], T[sub 3] uptake, TBG, cortisol, IgE, CA125, PAP, and [beta][sub 2]-microglobulin, revealing satisfactory results. There was a great 'within kit variation' between facilities in ACTH, free T[sub 4], and calcitonin; and there was a great 'between kit variation' in ACTH, LH, free T[sub 4], thyroglobulin, PTH, calcitonin, and [alpha]-fetoprotein. (N.K.).

  17. Metallurgy, Visual Inspection, Hardness and Liquid Penetrant Testing, Aviation Quality Control 2: 9227.01.

    Science.gov (United States)

    Dade County Public Schools, Miami, FL.

    The course consists of the basic and simpler methods of inspecting and nondestructive testing of parts and materials to insure the quality and reliability of the finished product. The outline consists of six blocks totaling 135 hours: (1) defects in the metal ingot, (2) defects resulting from processing metals, (3) defects in metals in service,…

  18. Quality control of the analysis of histamine in fish by proficiency test

    Science.gov (United States)

    Evangelista, Warlley P.; Tette, Patrícia A. S.; Gloria, Maria Beatriz A.

    2015-01-01

    The analysis of histamine is required by the European Union for the importation of tuna and other Scombroid fish. The aim of this study was to investigate the quality of the analysis of histamine in fish, by means of reference material (RM) and of proficiency test (PT). Sample analysis carried out using RM provided 89.4% recovery. During the proficiency test, the histamine content of the sample was 311.9 mg/kg and the z-score was zero. These results assure the good performance of the laboratory in the analysis of histamine in fish, asuring reliability of results to clients.

  19. A simple and sensitive quality control method of the anaerobic atmosphere for identification and antimicrobial susceptibility testing of anaerobic bacteria

    DEFF Research Database (Denmark)

    Justesen, Tage; Justesen, Ulrik Stenz

    2013-01-01

    The maintenance of a strict anaerobic atmosphere is essential for the culture of strict anaerobic bacteria. We describe a simple and sensitive quality control method of the anaerobic atmosphere, based on the measurement of the zone diameter around a 5-μg metronidazole disk when testing an aerotol...

  20. Quality control in diagnostic molecular pathology in the Netherlands; proficiency testing for patient identification in tissue samples.

    NARCIS (Netherlands)

    Thunnissen, F.B.J.M.; Tilanus, M.G.J.; Ligtenberg, M.J.L.; Nederlof, P.M.; Dinjens, W.N.; Meulemans, E.; Brule, A.J. van den; Noesel, C.J. van; Leeuw, W. de; Schuuring, E.

    2004-01-01

    AIMS: To describe the evolution of proficiency testing for molecular diagnostic pathology with respect to determining unambiguously the patient identity of tissue samples by microsatellite analysis. METHOD: Four rounds of quality control exchanges of samples from different patients were sent with th

  1. Quality-Control Analytical Methods: Microbial-Testing Aspects of USP Chapter 797 for Compounded Sterile Preparations.

    Science.gov (United States)

    Kupiec, Thomas C

    2005-01-01

    The standards set forth by the United States Pharmacopeia (USP) Chapter 797 have now been in effect since January 1 or 2004. As the first practice standards of sterile pharmacy compounding in US history, they have "attracted both respect and criticism" because they have also been cited as a practice expectation by the Joint Commission on Accreditation of Healthcare Organizations. USP 797 expands the scope of facilities governed by the regulatinos and defines the practices covered, emphasizing the importance of environmental quality and control, verification of accuracy and sterility, training and evaluation, quality control after preparations leave the pharmacy, patient monitoring and adverse events reporting. The purpose of this article is to help the reader understand the criteria set forth by USP Chapter 797 regarding finished-product testing, including criteria for the microbial-testing aspects of sterility testing (USP Chapter 71) and endotoxin (pyrogen) testing (USP Chapter 85).

  2. Implementation of basic quality control tests for malaria medicines in Amazon Basin countries: results for the 2005–2010 period

    Directory of Open Access Journals (Sweden)

    Pribluda Victor S

    2012-06-01

    Full Text Available Abstract Background Ensuring the quality of malaria medicines is crucial in working toward malaria control and eventual elimination. Unlike other validated tests that can assess all critical quality attributes, which is the standard for determining the quality of medicines, basic tests are significantly less expensive, faster, and require less skilled labour; yet, these tests provide reproducible data and information on several critical quality attributes, such as identity, purity, content, and disintegration. Visual and physical inspection also provides valuable information about the manufacturing and the labelling of medicines, and in many cases this inspection is sufficient to detect counterfeit medicines. The Promoting the Quality of Medicines (PQM programme has provided technical assistance to Amazon Malaria Initiative (AMI countries to implement the use of basic tests as a key screening mechanism to assess the quality of malaria medicines available to patients in decentralized regions. Methods Trained personnel from the National Malaria Control Programmes (NMCPs, often in collaboration with country’s Official Medicine Control Laboratory (OMCL, developed country- specific protocols that encompassed sampling methods, sample analysis, and data reporting. Sampling sites were selected based on malaria burden, accessibility, and geographical location. Convenience sampling was performed and countries were recommended to store the sampled medicines under conditions that did not compromise their quality. Basic analytical tests, such as disintegration and thin layer chromatography (TLC, were performed utilizing a portable mini-laboratory. Results Results were originally presented at regional meetings in a non-standardized format that lacked relevant medicines information. However, since 2008 information has been submitted utilizing a template specifically developed by PQM for that purpose. From 2005 to 2010, the quality of 1,663 malaria medicines

  3. Implementation of basic quality control tests for malaria medicines in Amazon Basin countries: results for the 2005-2010 period.

    Science.gov (United States)

    Pribluda, Victor S; Barojas, Adrian; Añez, Arletta; López, Cecilia G; Figueroa, Ruth; Herrera, Roxana; Nakao, Gladys; Nogueira, Fernando Ha; Pianetti, Gerson A; Povoa, Marinete M; Viana, Giselle Mr; Gomes, Margarete S Mendonça; Escobar, Jose P; Sierra, Olga L Muñoz; Norena, Susana P Rendon; Veloz, Raúl; Bravo, Marcy Silva; Aldás, Martha R; Hindssemple, Alison; Collins, Marilyn; Ceron, Nicolas; Krishnalall, Karanchand; Adhin, Malti; Bretas, Gustavo; Hernandez, Nelly; Mendoza, Marjorie; Smine, Abdelkrim; Chibwe, Kennedy; Lukulay, Patrick; Evans, Lawrence

    2012-06-15

    Ensuring the quality of malaria medicines is crucial in working toward malaria control and eventual elimination. Unlike other validated tests that can assess all critical quality attributes, which is the standard for determining the quality of medicines, basic tests are significantly less expensive, faster, and require less skilled labour; yet, these tests provide reproducible data and information on several critical quality attributes, such as identity, purity, content, and disintegration. Visual and physical inspection also provides valuable information about the manufacturing and the labelling of medicines, and in many cases this inspection is sufficient to detect counterfeit medicines. The Promoting the Quality of Medicines (PQM) programme has provided technical assistance to Amazon Malaria Initiative (AMI) countries to implement the use of basic tests as a key screening mechanism to assess the quality of malaria medicines available to patients in decentralized regions. Trained personnel from the National Malaria Control Programmes (NMCPs), often in collaboration with country's Official Medicine Control Laboratory (OMCL), developed country- specific protocols that encompassed sampling methods, sample analysis, and data reporting. Sampling sites were selected based on malaria burden, accessibility, and geographical location. Convenience sampling was performed and countries were recommended to store the sampled medicines under conditions that did not compromise their quality. Basic analytical tests, such as disintegration and thin layer chromatography (TLC), were performed utilizing a portable mini-laboratory. Results were originally presented at regional meetings in a non-standardized format that lacked relevant medicines information. However, since 2008 information has been submitted utilizing a template specifically developed by PQM for that purpose. From 2005 to 2010, the quality of 1,663 malaria medicines from seven AMI countries was evaluated, mostly

  4. A proposal for an alternative quality control test procedure for inactivated vaccines against food-and-mouth disease virus.

    Science.gov (United States)

    Molin-Capeti, K C; Sepulveda, L; Terra, F; Torres-Pioli, M F; Costa-Casagrande, T; França, S C; Thomaz-Soccol, V

    2013-02-18

    Foot-and-mouth disease (FMD) control in Brazil includes a strict mandatory vaccination program with vaccines produced in certified laboratories subject to inspection by the Brazilian Ministry of Agriculture, Livestock, and Food Supply (MAPA). The FMD vaccine's potency is tested through antibodies titration against structural viral proteins in sera from cattle that have not had any exposure to food-and-mouth disease virus (FMDV), at 28 days post-vaccination. Biological product testing using large animals is expensive and unwieldy. Thus, alternative testing procedures using laboratory animals have been proposed for quality control of these products. Such biological methods for vaccine evaluation using animals from vivarium facilities can have a significant impact through reduced costs, easier handling, and shorter testing times. The present study was designed to access Balb/C mice's humoral immune responses to a FMDV experimental vaccine, the composition of which contains three virus serotypes of FMDV (O1 Campos, A24 Cruzeiro, and C3 Indaial). Balb/C mice were immunized at doses that were 5% and 10% of the vaccine volume administered in cattle. Immunized mice had their antibody titers probed at 14, 21, and 28 DPV (days post vaccination). The results obtained were compared to those previously known from cattle's immune responses to the FMDV vaccine. An adequate immune response to the vaccine was seen with 10% formulation at 21 DPV. The study results are encouraging and indicate that the mouse model can be used for quality control in experimental vaccine testing.

  5. FLEXURAL TESTING MACHINE AS AN OFF-LINE CONTROL SYSTEM FOR QUALITY MONITORING IN THE PRODUCTION OF BENDED CERAMIC TILES

    Directory of Open Access Journals (Sweden)

    Cristiano Fragassa

    2016-06-01

    Full Text Available The capability to bend in a controlled manner Gres Porcelain stoneware tiles passing by a very exclusive process of pyroplastic deformation opens up entirely new opportunities in utilisation of this important family of ceramics. A bended tile can be exploited in innovative applications, such as stairs, shelves, benches and even radiators, turning this element from a simple piece of furnishing in a modern functional component. But this change in functionality also requires a different approach in the quality control, both at the product and process levels, that can no longer be limited to the use of tests specified in the regulations for traditional ceramics (e.g. colour, porosity, hygroscopic .... This article describes the first device so far devised for the verification of resistance to bending of curved tiles, discussing the correct way of use. The adoption of this particular equipment as an off-line control device can represent a valid strategy for monitoring the product and process quality.

  6. Control of quality in the tests of systems of containment of vehicles. Intercomparison of the results of the tests; Control de calidad en los ensayos de sistemas de contencion de vehiculos. Intercomparacion de los resultados de los ensayos

    Energy Technology Data Exchange (ETDEWEB)

    Lopez Ramos, S.

    2009-07-01

    This article tries to offer information on how Central Laboratory of Structures and Materials are made the tests for Marca N of AENOR of the systems of containment of vehicles and its control of external quality. (Author) 15 refs.

  7. The 10th quality control survey for radioisotope in vitro tests in Japan, 1988

    Energy Technology Data Exchange (ETDEWEB)

    1989-10-01

    This report presents the results of the 10th quality control nationwide survey. Of 780 selected facilities, 471 (60.4%) participated in this survey. Items examined were as follows: alpha-fetoprotein (AFP), aldosterone; beta microglobulin, carbohydrate antigen (CA) 15-3, C peptide, digoxin, elastase 1, free triiodothyronine (FT{sub 3}), gastrin, growth hormone, human chorionic gonadotropin (HCG), immunoglobulin E, prostatic acid phosphatase (PAP), pancreatic secretory trypsin inhibitor, progesterone, prolactine, thyroglobulin, triiodothyronine (T{sub 3}), triiodothyronine uptake (T{sub 3} U), tissue polypeptide antigen (TPA), thyroid stimulating hormone (TSH), and testosterone. 'Within kit variation' between facilities showed a coefficient of variation (CV) of more than 15% for AFP, FT , gastrin, HCG, progesterone, prolactine II, thyroglobulin, and TSH; and 'between kit variation' showed a CV of more than 15% for AFP, aldosterone, gastrin, IgE, PAP, progesterone, prolactin II, thyroglobuline, TSH, and testosterone. In comparing annual changes in CV, the following items were improved: aldosterone, C-peptide, gastrin, TPA, and TSH for 'within kit variation'; andaldosterone, C-peptide, gastrin, T{sub 3}, T{sub 3} U, TSH, and testosterone for 'between kit variation'. (N.K.).

  8. Quality Control of Extruded HVDC Cables: Detection of Critical Flaws Using Low Frequency Voltage Endurance Testing%Quality Control of Extruded HVDC Cables: Detection of Critical Flaws Using Low Frequency Voltage Endurance Testing

    Institute of Scientific and Technical Information of China (English)

    Erling Ildstad; Frank Mauseth; Mildrid Selsjord; Roll Hegerberg

    2011-01-01

    The main purpose of the work presented here is to evaluate different methods for quality control of polymer- ic insulated HVDC cables. The insight gained can be used to evaluate proposed test methods for quality assurance of long lengths of polymer insulated power cables. Laboratory experiments were performed using both Rogowski shaped test objects and model cables, insulated with XLPE containing imbedded spherically shaped particles. Tests were per- formed by stressing the test object with AC (50 Hz), VLF (0.1 Hz) and DC voltages and measuring time to break- down at the different voltages. The slope of the voltage-time curve for 0. land 50 Hz were found to be parallel show- ing higher breakdown strength for 0.1 Hz than 50 Hz. The number of periods to breakdown is somewhat higher for 0.1 Hz than for 50 Hz. The breakdown strength for DC was~ much higher than for both AC 50 Hz and 0.1 Hz. The results indicate that the VLF test voltage needs to be 2 to 3 times higher than at 50 Hz power frequency in order to eliminate the same defects within a comparable time.

  9. Comparative analysis of quality control tests on computed tomography in accordance with national and international laws; Analise comparativa dos testes de controle de qualidade em tomografia computadorizada de acordo com as legislacoes nacional e internacional

    Energy Technology Data Exchange (ETDEWEB)

    Ramos, Fernando S.; Vasconcelos, Rebeca S.; Goncalves, Marcel S.; Oliveira, Marcus V.L. de, E-mail: fernando_siramos@hotmail.com, E-mail: marcusradiology@gmail.com [Instituto Federal da Bahia (IFBA), Salvador, BA (Brazil)

    2014-07-01

    The objective of this study is to perform a comparative analysis between the Brazilian legislation and internationals protocols, with respect to the quality control tests for computerized tomography. We used 07 references, published from 1998-2012: the Protocolo Brasileiro - Portaria 453/98 SVS/MS and the Guia de Radiodiagnostico Medico da ANVISA; Quality Assurance Programme for Computed Tomography: Diagnostic and Therapy Applications of the IAEA; European Protocol - European Guidelines on Quality Criteria for Computed Tomography of the EUR No. 16262 EN; Radiation Protection No. 162 - Criteria for Acceptability of Medical Radiology, Nuclear Medicine and Radiotherapy of the European Commission; the Protocols of Control de Calidad en Radiodiagnostico IAEA / ARCAL XLIX; and the Protocolo Espanol de Control de Calidad en Radiodignostico. The comparative analysis of these legislations was based on aspects of tolerance / limit, frequency and objectives of the recommended tests. Were found 18 tests in the Brazilian legislation. The tests were grouped according to their nature (dosimetric tests / exposure and geometric tests and image quality tests). Among the evaluated protocols was identified divergence between tests contained in the documents and the criteria of assessment set out in this work. It is clear, moreover, that for certain documents are not observed tolerances, well-defined methodologies and even frequency of testing. We conclude that the current legislation in Brazil differs in certain respects from international protocols analyzed, although this has a great numbers of quality control tests. However, it is necessary that the Brazilian legislation takes into account technological advances presented to time.

  10. Quality Control Applications

    CERN Document Server

    Chorafas, Dimitris N

    2013-01-01

    Quality control is a constant priority in electrical, mechanical, aeronautical, and nuclear engineering – as well as in the vast domain of electronics, from home appliances to computers and telecommunications. Quality Control Applications provides guidance and valuable insight into quality control policies; their methods, their implementation, constant observation and associated technical audits. What has previously been a mostly mathematical topic is translated here for engineers concerned with the practical implementation of quality control. Once the fundamentals of quality control are established, Quality Control Applications goes on to develop this knowledge and explain how to apply it in the most effective way. Techniques are described and supported using relevant, real-life, case studies to provide detail and clarity for those without a mathematical background. Among the many practical examples, two case studies dramatize the importance of quality assurance: A shot-by-shot analysis of the errors made ...

  11. Estimation of compressive strength based on Pull-Out bond test results for on-site concrete quality control

    Directory of Open Access Journals (Sweden)

    M. S. Lorrain

    Full Text Available Quality control of structural concrete has been conducted for several decades based mainly on the results of axial compression tests. This kind of test, although widely used, is not exempt from errors and has some considerable drawbacks that may affect its reliability, such as the need for appropriate and careful specimen conditioning and adoption of adequate capping techniques. For these reasons, it would be useful to have complementary or alternative ways to check compressive strength, in order to improve concrete quality control. The use of a bond test to monitor concrete strength is being proposed by an international group of researchers from France, Tunisia and Brazil as a potential means to this end. Given the fact that the link between bond resistance and concrete strength is already well established, this type of test seems to be a viable alternative to traditional methods. Nonetheless, to check if the underlying principle is sound when used in different circumstances, the group has been gathering data from several studies conducted by different researchers in various countries, with distinct concretes and rebar types. An analysis of the data collected shows that there is a clear and strong correlation between bond resistance and compressive strength, no matter the influence of other variables. This result validates the basic idea of using an Appropriate Pull-Out (APULOT bond test to assess concrete strength. If the general principle is valid for random data obtained from different studies, the definition of a clear and appropriate test will probably lead to the reduction of experimental noise and increase the precision of the strength estimates obtained using this method.

  12. Software product quality control

    CERN Document Server

    Wagner, Stefan

    2013-01-01

    Quality is not a fixed or universal property of software; it depends on the context and goals of its stakeholders. Hence, when you want to develop a high-quality software system, the first step must be a clear and precise specification of quality. Yet even if you get it right and complete, you can be sure that it will become invalid over time. So the only solution is continuous quality control: the steady and explicit evaluation of a product's properties with respect to its updated quality goals.This book guides you in setting up and running continuous quality control in your environment. Star

  13. Eddy Current, Magnetic Particle and Hardness Testing, Aviation Quality Control (Advanced): 9227.04.

    Science.gov (United States)

    Dade County Public Schools, Miami, FL.

    This unit of instruction includes the principles of eddy current, magnetic particle and hardness testing; standards used for analyzing test results; techniques of operating equipment; interpretation of indications; advantages and limitations of these methods of testing; care and calibration of equipment; and safety and work precautions. Motion…

  14. Quality control analytical methods: microbial limit tests for nonsterile pharmaceuticals, Part 1.

    Science.gov (United States)

    Vu, Nicole; Lou, Jessica R; Kupiec, Thomas C

    2014-01-01

    Contamination of pharmaceuticals with microorganisms may lead to deleterious effects on the therapeutic properties of the drug, and may potentially cause injuries to intended recipients. Cases of contaminated nonsterile products have been reported in increasing numbers, and often associated with the presence of objectionable microorganisms. Methods for detection of these organisms are described in three major Pharmacopeias. Their functions and their limitations in the examination of microbiological quality for nonsterile products will be reviewed in this report.

  15. Accelerator Magnet Quench Heater Technology and Quality Control Tests for the LHC High Luminosity Upgrade

    CERN Document Server

    Meuter, Florian

    The High Luminosity upgrade of the Large Hadron Collider (HL-LHC) foresees the installation of new superconducting Nb3Sn magnets. For the protection of these magnets, quench heaters are placed on the magnet coils. The quench heater circuits are chemically etched from a stainless steel foil that is glued onto a flexible Polyimide film, using flexible printed circuit production technology. Approximately 500 quench heaters with a total length of about 3000 m are needed for the HL-LHC magnets. In order to keep the heater circuit electrical resistance in acceptable limits, an approximately 10 µm-thick Cu coating is applied onto the steel foil. The quality of this Cu coating has been found critical in the quench heater production. The work described in this thesis focuses on the characterisation of Cu coatings produced by electrolytic deposition, sputtering and electron beam evaporation. The quality of the Cu coatings from different manufacturers has been assessed for instance by ambient temperature electrical res...

  16. Checking quality control?

    DEFF Research Database (Denmark)

    Brodersen, Lars

    2005-01-01

    How is quality control doing within the community of GIS, web-services based on geo-information, GI etc.?......How is quality control doing within the community of GIS, web-services based on geo-information, GI etc.?...

  17. Quality control tests of an activity meter to be used as reference for an in situ calibration methodology

    Energy Technology Data Exchange (ETDEWEB)

    Correa, Eduardo de L.; Kuahara, Lilian T.; Potiens, Maria da Penha A., E-mail: educorrea1905@gmail.com [Instituto de Pesquisas Energeticas e Nucleares (IPEN/CNEN-SP), Sao Paulo, SP (Brazil)

    2013-07-01

    The Nuclear Medicine is a medical speciality involving the application of radioactive isotopes in diagnosis and/or treatment of disease. In order to ensure that the radiation dose applied to the patient is adequate, the radiopharmaceutical activity must be adequately measured. This work was performed to analyze the behavior of an activity meter Capintec NPL-CRC to be used as a reference for the implementation of a methodology for in situ calibration of nuclear medicine equipment. It were made the daily quality control tests, such as auto zero, background, system test, accuracy test and constancy test, and determination of repeatability and intermediate measurement precision using {sup 137}Cs, {sup 57}Co and {sup 133}Ba sources.Furthermore, this equipment was used to confirm the check sources activities produced at IPEN and used by the laboratory that produces the radiopharmaceuticals sent to the nuclear medicine services. The results showed a good behavior of this equipment. The maximum variation obtained in the accuracy test was of 1.81% for the {sup 57}Co source. For {sup 137}Cs this variation was of 4.59%, and for {sup 133}Ba, 11.83%. The high value obtained for the last case, indicates the needs of a correction that can be obtained by calibration methods. The result obtained using different reference sources showed a great repeatability with maximum variation of 1.38%. (author)

  18. Orally inhaled drug performance testing for product development, registration, and quality control.

    Science.gov (United States)

    Lastow, Orest; Svensson, Mårten

    2014-12-01

    A DPI can be split into three different modules; device, formulation, process. These are developed in parallel, and together with the user they provide the performance of an inhalation product. During product development, these modules are evolving and changing, whereas the requirements on an inhalation product are always expressed in terms of the performance of the final commercial product. To do performance testing during development when the product is not finished presents many challenges and can be confusing and misleading. During development, the performance of the final product is typically being predicted by testing ever changing prototypes. This article describes methods and approaches to manage such development and to, during development, provide relevant predictions of the in vitro and in vivo performances of the final product.

  19. [Approval of ISO/IEC 17025 and quality control of laboratory testing].

    Science.gov (United States)

    Yamamoto, Shigeki; Asakura, Hiroshi; Machii, Kenji; Igimi, Shizunobu

    2010-01-01

    First section of Division of Biomedical Food Research, National Institute of Health Sciences (NIHS) was approved by ISO/IEC 17025 as a laboratory having an appropriate laboratory testing technique. NIHS is the first national laboratory approved by ISO/IEC 17025. NIHS has also been accepted the appropriate technique and facility for the BSL3 level pathogens by ISO/IEC 17025. NIHS is necessary to take an external audit almost every year. This approval is renewed every 4 years.

  20. Summary. The 19th quality control survey for radioisotope in vitro tests in Japan, 1997

    Energy Technology Data Exchange (ETDEWEB)

    Shishiba, Yoshimasa; Shimizu, Taeko [Toranomon Hospital, Tokyo (Japan); Ichihara, Kiyoshi; Kousaka, Tadako; Kobayashi, Hisae; Tsushima, Toshio; Hoshino, Minoru; Mori, Mikio

    1998-11-01

    This summary concerns results of the survey in the title performed by the Subcommittee for Radioisotope in vitro Test in the Medical and Pharmaceutical Committee, Japan Radioisotope Association. The survey was conducted in 161 facilities in Japan including public and private hospitals, health institutes and reagent manufacturers. Samples were sent to the facilities and subjected to examinations of intra- and inter-day reproducibility, freeze-thawing effects and periodical changes of the measured values. Methods employed were RIA, IRMA, EIA, ELISA, LPIA, PAMIA, FIA, FPIA, NIA, LAT, CLIA and ECLIA. Results were analyzed by variation coefficients in the kit and between the kits. Samples were for: growth hormone, somatomedin C, follicle stimulating hormone, luteinizing hormone, prolactin, thyroid stimulating hormone, triiodothyronine, thyroxine, thyroxine binding globulin, calcitonin, insulin, C-peptide, glucagon, gastrin, testosterone, estradiol, progesterone, {beta}human chorionic gonadotropin, 17{alpha}-hydroxyprogesterone, aldosterone, cortisol, dehydroepiandrosterone, renin, immunogloblin E, digoxin, {alpha}-fetoprotein, carcinoembryonic antigen, tissue polypeptide antigen, CA125, CA19-9, CA15-3, prostatic acid phosphatase, prostate specific antigen, {beta}{sub 2}-microgloblin and ferritin. Results were found rather unsatistactory for some products in the clinical practice, necessary for improvement of detection for some tests and needed for some kits for solving the problems of difference between kits and of matrix effect. (K.H)

  1. 尿液检验的质量控制探析%Quality Control of Urine Test

    Institute of Scientific and Technical Information of China (English)

    吴永岳; 黎雪英; 王丽英

    2013-01-01

    Objective To investigate the impact of the process of testing urine test the quality of a variety of factors, for various reasons, to find an effective way to control the quality of the examinations. Methods A retrospective analysis, our hospital laboratory from January 2009 to December 2012 to close inspection of the 49358 copies of the data were analyzed urine samples, which will be a larger deviation of the test results to 209 samples for research object. Specific inquiry is before analysis, analysis, and analysis of what factors lead to biased results. Specific analysis of urine tests in order to influence the process of testing the quality characteristics, and promote quality control depth. Results Through the close examination of our hospital laboratory test results showed a larger deviation of 209 samples was analyzed. Prior to analysis the main factors affecting the quality of collected data logging, sample collection method error, the sample delivery errors, accounting for 29.67%(62/209). Analysis of the main factors affecting the quality inspection staff operational errors, wrong test equipment or reagents, urine sediment examination errors, accounting for 46.89%(98/209). Analysis of the main factors affecting the quality of the sample results examined mistakes, mistakes in sample results delivery, accounting for 23.44%(49/209). Conclusion We conducted a urine test is an important adjunct to clinical diagnosis, the hospital every day to work a lot of urine tests. How to protect the quality of the urine test, that is, we need to attach great importance to the relevant staff work. We should pay attention to the work of the whole urine flow, treat each step carefully to ensure the smooth progress of urine.%目的:探讨尿液检验过程中影响检验质量的各种因素,针对各种原因来找到控制检验质量的有效途径。方法利用回顾性分析的方法,对我院检验科于2009年1月至2012年12月收检的49358份尿检样本的

  2. Development of a nomogram to estimate the quality of life in asthmatic children using the Childhood Asthma Control Test.

    Science.gov (United States)

    Montalbano, Laura; Cilluffo, Giovanna; Gentile, Manuel; Ferrante, Giuliana; Malizia, Velia; Cibella, Fabio; Viegi, Giovanni; Passalacqua, Giovanni; La Grutta, Stefania

    2016-08-01

    Pediatric Asthma Quality of Life Questionnaire (PAQLQ) provides detailed information on QoL in asthmatic children, whereas Childhood Asthma Control Test (C-ACT) Questionnaire is the most validated instrument for asthma control. No study assessed the relationship between C-ACT and QoL in children by means of those instruments. The aim of this study was to determine whether a QoL estimation is possible using the C-ACT questionnaire in asthmatic children. Medical history, spirometry, C-ACT, and PAQLQ were assessed in 144 (60% male) outpatient asthmatic children from September 2011 to November 2014. A generalized linear model (GLM) for the prediction of PAQLQ was obtained through a stepwise procedure starting from a full model with all C-ACT items, and predictive nomograms were created. Fifty-five (38%) well-controlled (WC) asthma, 37 (26%) partially controlled (PC) asthma, and 52 (36%) uncontrolled asthma (UA) patients were enrolled. Persistent asthmatics (PA) were significantly more uncontrolled (p children in usual clinical care. © 2016 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  3. Daily quality controls analysis of a CT scanner simulator; Analise dos testes diarios de controle de qualidade de um tomografo simulador

    Energy Technology Data Exchange (ETDEWEB)

    Vasques, Maira Milanelo; Santos, Gabriela R.; Furnari, Laura, E-mail: maira.vasques@hc.fmusp.br [Universidade de Sao Paulo (USP), Sao Paulo, SP (Brazil). Faculdade de Medicina

    2016-07-01

    With the increasing technological developments, radiotherapy practices, which allow for better involvement of the tumor with the required therapeutic dose and minimize the complications of normal tissues, have become reality in several Radiotherapy services. The use of these resources in turn, was only possible due to the progress made in planning based on digital volumetric images of good quality, such as computed tomography (CT), which allow the correct delimitation of the tumor volume and critical structures. Specific tests for quality control in a CT scanner used in radiotherapy, named CT simulator, should be applied as part of the institutional Quality Assurance Program. This study presents the methodology used in the Instituto de Radiologia do Hospital das Clinicas da Faculdade de Medicina da Universidade de Sao Paulo (HCFMUSP) for daily testing of the CT scanner simulator and the results obtained throughout more than two years. The experience gained in the period conducted showed that the tests are easy to perform and can be done in a few minutes by a trained professional. Data analysis showed good reproducibility, which allowed the tests could be performed less frequently, after 16 months of data collection. (author)

  4. An alternative to animal testing in the quality control of erythropoietin.

    Science.gov (United States)

    Zimmermann, H; Gerhard, D; Hothorn, L A; Dingermann, T

    2011-06-01

    A physico-chemical method has been developed as an alternative to the current bioassay in normocythaemic mice for estimating the biological activity of erythropoietin batches. Capillary zone electrophoresis was used for quantification of the isoforms and their substructures were further elucidated by N-glycan mapping techniques. The analytical study was carried out on a total of 40 batches of epoetin beta which were selected to cover an adequate range of precisely established potency values. The relationship between the biological and chemical parameters was evaluated statistically in order to identify suitable covariates for the prediction of the biological activity. Out of several alternatives, a prediction model which is based on the percentages of isoforms per batch and the degree of sialidation was selected and tested. This model is comparable in terms of accuracy to the established in vivo bioassay, but is far superior in terms of precision. Further advantages of the method are improved animal welfare and savings in time and effort. The question whether the prediction model already meets the requirements for replacing the bioassay according to the ICH guideline Q6B is discussed.

  5. [Quality controls in medical mycology].

    Science.gov (United States)

    Kauffmann-Lacroix, C; Cassaing, S; Bessieres, M-H; Mayet, D; Linas, M-D; Roques, C

    2011-03-01

    The Quality Management System in medical mycology refers to the systematic monitoring with internal and external quality controls: it needs to be organized in the laboratory. ISO 15189 standard is not precise in how to demonstrate the correctness of tests, in terms of frequency and requirements for quality controls QC. That's why the COFRAC, the French Accreditation Committee has published guides to which we should refer. The laboratory has to apply internal Quality Control Programs. They consist of various tests to check the reagents including the culture media. Reference strains have to be provided and preparations of homemade reagents are needed, because few are commercialized. Maintaining the competence of the technical staff through identification of unknown strains is also required. In the fungal serology field, home made antibodies with pooled sera or antigen controls are needed. This monitoring has to follow the recommandations from the Cofrac technical guide LAB GTA 06. For quantitative analysis, the Levey-Jennings chart is a graph with quality control data plotted on to give a visual indication. Some external QC references, besides the national quality control AFSSAPS, are available. Data evaluation, corrective actions in case of out of range results and preventive actions have to be determined in the Quality System documents and presented in the annual management review. Copyright © 2011. Published by Elsevier SAS.

  6. Systems Engineering, Quality and Testing

    Science.gov (United States)

    Shepherd, Christena C.

    2015-01-01

    AS9100 has little to say about how to apply a Quality Management System (QMS) to aerospace test programs. There is little in the quality engineering Body of Knowledge that applies to testing, unless it is nondestructive examination or some type of lab or bench testing. If one examines how the systems engineering processes are implemented throughout a test program; and how these processes can be mapped to AS9100, a number of areas for involvement of the quality professional are revealed.

  7. Association between product quality control and process quality control of bulk milk

    NARCIS (Netherlands)

    Velthuis, A.; Asseldonk, van M.A.P.M.

    2010-01-01

    Assessment of dairy-milk quality is based on product quality control (testing bulk-milk samples) and process quality control (auditing dairy farms). It is unknown whether process control improves product quality. To quantify possible association between product control and process control a statisti

  8. Test Control Center (TCC)

    Data.gov (United States)

    Federal Laboratory Consortium — The Test Control Center (TCC) provides a consolidated facility for planning, coordinating, controlling, monitoring, and analyzing distributed test events. ,The TCC...

  9. 40 CFR 51.359 - Quality control.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 2 2010-07-01 2010-07-01 false Quality control. 51.359 Section 51.359....359 Quality control. Quality control measures shall insure that emission testing equipment is calibrated and maintained properly, and that inspection, calibration records, and control charts...

  10. Microbiological Testing Quality Control Media%微生物检验中培养基的质量控制

    Institute of Scientific and Technical Information of China (English)

    蒋淑宏

    2015-01-01

    目的:探讨微生物中检验培养基的质量的控制及相关对策的分析。方法在培养微生物的实验中,通过对微生物培养基的相关的配制、灭菌、无菌试验等方面进行分析,并对其性能进行测试,记录相关的数据进行整理与分析。结果选用玻璃、搪瓷或不锈钢制品作为配制培养基所用的容器,而培养所用的基液则是采用蒸馏水;记录好灭菌前后应测定的数值;并对PH值进行测定,每次都要做出详细的记录,采用高压灭菌时,温度要保持在121℃,时间为15 min,在进行微生物的检验时,应对其性能进行测试,其保质期在2~3年之间,若是开封的则为6个月;配制培养基的电子秤和酸度计应每年进行检定。结论在培养微生物的基时,要对微生物基的质量进行严格的控制,才能确保微生物检验结果的准确性和可靠性。%Objective To investigate the test medium in the quality control of microorganisms and related countermeasures, in order to improve the quality of the medium.Methods In the experimental microbial culture through the medium of the relevant aspects of the microbial preparation, sterilization, sterile test were analyzed, and tested its performance, recording relevant data colection and analysis. ResultsThe selection of glass, enamel or stainless steel products used in the preparation of the medium as a container, and the liquid culture medium used is the use of distiled water; sterilization records should be measured before and after a good value; and PH values measured per times have to make detailed records, when using the autoclave, the temperature is maintained at 121 ℃, time is 15 min, before the microbial culture groups, respond to test its performance, its shelf life of between 2 to 3 years, If have been opened, compared with six months; preparation of the medium makes the electronic balance and acidity test should be carried out annualy

  11. An Entropy Testing Model Research on the Quality of Internal Control and Accounting Conservatism: Empirical Evidence from the Financial Companies of China from 2007 to 2011

    Directory of Open Access Journals (Sweden)

    Zongrun Wang

    2014-01-01

    Full Text Available We set information disclosure of internal control as a starting point to explore the relationship between the quality of internal control and accounting conservatism, and then adopt the entropy testing model to calculate the index of the internal control quality with the sample data of Chinese listed companies in financial industry from 2007–2011. Regression results show that earnings conservatism exists. The stronger the internal control is, the higher the accounting conservatism can be. Companies which have enhanced their internal control are more conservative, and these results make no difference with other industries.

  12. Development of a standardized susceptibility test for Campylobacter with quality control ranges for ciprofloxacin, doxycycline, erythromycin, gentamicin, and meropenem

    DEFF Research Database (Denmark)

    McDermott, P. F.; Bodeis, S. M.; Aarestrup, Frank Møller

    2004-01-01

    -control (QC) strain. Minimal inhibitory concentration (MIC) QC ranges were determined for two incubation time/temperature combinations: 36degreesC for 48 hr and 42degreesC for 24 hr. Quality-control ranges were determined for ciprofloxacin, doxycycline, erythromycin, gentamicin, and meropenem. For all...

  13. COAL QUALITY CONTROL

    Institute of Scientific and Technical Information of China (English)

    孟祥瑞

    1998-01-01

    Coal storing and loading have much more influence on coal quality. In the paper, a goalprogramming model has been constructed to determine the ideal quantity extracting from stockpileand silos and a quality control model is inferred under the guidance of maximum theory ofdispersed number and practice methods are given to meet production demand, with which a coalmine has achieved a better tech-economic result.

  14. Quality Management, Quality Assurance and Quality Control in Blood Establishments

    OpenAIRE

    Bolbate, N

    2008-01-01

    Quality terms and the roots of the matter are analyzed according to European Committee’s recommendations. Essence of process and product quality control as well as essence of quality assurance is described. Quality system’s structure including quality control, quality assurance and management is justified in the article.

  15. Association between product quality control and process quality control of bulk milk

    OpenAIRE

    Velthuis, A.; Asseldonk, van, M.M.L.

    2010-01-01

    Assessment of dairy-milk quality is based on product quality control (testing bulk-milk samples) and process quality control (auditing dairy farms). It is unknown whether process control improves product quality. To quantify possible association between product control and process control a statistical analysis was conducted. The analysis comprised 64.373 audit results on 26,953 dairy farms and all conducted lab tests of bulk-milk samples two, six or 12 months before the audit. Lab results in...

  16. VGI QUALITY CONTROL

    Directory of Open Access Journals (Sweden)

    C. C. Fonte

    2015-08-01

    Full Text Available This paper presents a framework for considering quality control of volunteered geographic information (VGI. Different issues need to be considered during the conception, acquisition and post-acquisition phases of VGI creation. This includes items such as collecting metadata on the volunteer, providing suitable training, giving corrective feedback during the mapping process and use of control data, among others. Two examples of VGI data collection are then considered with respect to this quality control framework, i.e. VGI data collection by National Mapping Agencies and by the most recent Geo-Wiki tool, a game called Cropland Capture. Although good practices are beginning to emerge, there is still the need for the development and sharing of best practice, especially if VGI is to be integrated with authoritative map products or used for calibration and/or validation of land cover in the future.

  17. FABRIC QUALITY CONTROL SYSTEMS

    Directory of Open Access Journals (Sweden)

    Özlem KISAOĞLU

    2006-02-01

    Full Text Available Woven fabric quality depends on yarn properties at first, then weaving preparation and weaving processes. Defect control of grey and finished fabric is done manually on the lighted tables or automatically. Fabrics can be controlled by the help of the image analysis method. In image system the image of fabrics can be digitized by video camera and after storing controlled by the various processing. Recently neural networks, fuzzy logic, best wavelet packet model on automatic fabric inspection are developed. In this study the advantages and disadvantages of manual and automatic, on-line fabric inspection systems are given comparatively.

  18. Quality assurance and control in the production and static tests of the solid rocket boosters for the Space Shuttle

    Science.gov (United States)

    Cerny, O. F.

    1979-01-01

    The paper surveys the various aspects of design and overhaul of the solid rocket boosters. It is noted that quality control is an integral part of the design specifications. Attention is given to the production process which is optimized towards highest quality. Also discussed is the role of the DCA (Defense Contract Administration) in inspecting the products of subcontractors, noting that the USAF performs this role for prime contractors. Fabrication and construction of the booster is detailed with attention given to the lining of the booster cylinder and the mixing of the propellant and the subsequent X-ray inspection.

  19. [Quality assurance in human genetic testing].

    Science.gov (United States)

    Stuhrmann-Spangenberg, Manfred

    2015-02-01

    Advances in technical developments of genetic diagnostics for more than 50 years, as well as the fact that human genetic testing is usually performed only once in a lifetime, with additional impact for blood relatives, are determining the extraordinary importance of quality assurance in human genetic testing. Abidance of laws, directives, and guidelines plays a major role. This article aims to present the major laws, directives, and guidelines with respect to quality assurance of human genetic testing, paying careful attention to internal and external quality assurance. The information on quality assurance of human genetic testing was obtained through a web-based search of the web pages that are referred to in this article. Further information was retrieved from publications in the German Society of Human Genetics and through a PubMed-search using term quality + assurance + genetic + diagnostics. The most important laws, directives, and guidelines for quality assurance of human genetic testing are the gene diagnostics law (GenDG), the directive of the Federal Medical Council for quality control of clinical laboratory analysis (RiliBÄK), and the S2K guideline for human genetic diagnostics and counselling. In addition, voluntary accreditation under DIN EN ISO 15189:2013 offers a most recommended contribution towards quality assurance of human genetic testing. Legal restraints on quality assurance of human genetic testing as mentioned in § 5 GenDG are fulfilled once RiliBÄK requirements are followed.

  20. Indoor Air Quality Test House

    Data.gov (United States)

    Federal Laboratory Consortium — Description:In order to enable studies of a range of indoor air quality and ventilation issues, EL maintains a highly instrumented three-bedroom test house. Previous...

  1. 品管圈活动在检验标本分析前质量控制中的应用%Application of Quality Control Circle in the Quality Control of Test Speci-mens before Analysis

    Institute of Scientific and Technical Information of China (English)

    段文丽

    2016-01-01

    Objective To research the effect of quality control circle in reducing the unqualified rate of test specimens be-fore analysis and provide effective basis for improving the quality of test specimens before analysis. Methods The specimen data with unqualified test results in our hospital from January 2016 to March 2016 were collected and statistically analyzed, and the unqualified ratio was calculated, and then the quality control circle group was established, and the activities in each phase of test specimens before analysis were analyzed by applying related management tools, and the unqualified reasons of specimens were analyzed, and the related measures were made for its reasons thus improving the quality of test specimens before analysis. Results 7014 cases of test specimens were collected before the quality control circle was implemented (from January 2016 to March 2016 ) including 39 cases of specimens with quality defect, and the unqualified rate was 5.56译, and 5417 cases of specimens were collected (April 2016 to June 2016) including 7 cases of specimens with defect, and the unqualified rate was 1.29 ‰, and the incidence rate of unqualified specimens obviously deceased compared with that before implementation, and the difference had statistical significance,P<0.001. Conclusion The quality control circle can improve the quality of test specimens before analysis, which is of important guidance significance to solving the clinical problems.%目的:研究“品管圈”活动用于降低检验标本分析前不合格率的效果,为提升检验标本分析前的质量提供有效的依据。方法收集该院2016年1-3月间检验结果不合格的标本资料,对其进行统计学分析,计算不合格比例。之后成立品管圈活动小组,应用相关的管理工具,解析检验标本分析前的各阶段活动,分析标本检验不合格的原因,针对其原因制定相关措施,提升检验标本分析前的质量。结

  2. Test Control Center exhibit

    Science.gov (United States)

    2000-01-01

    Have you ever wondered how the engineers at John C. Stennis Space Center in Hancock County, Miss., test fire a Space Shuttle Main Engine? The Test Control Center exhibit at StenniSphere can answer your questions by simulating the test firing of a Space Shuttle Main Engine. A recreation of one of NASA's test control centers, the exhibit explains and portrays the 'shake, rattle and roar' that happens during a real test firing.

  3. Interlaboratory Study of Quality Control Isolates for a Broth Microdilution Method (Modified CLSI M38-A) for Testing Susceptibilities of Dermatophytes to Antifungals▿

    Science.gov (United States)

    Ghannoum, M. A.; Arthington-Skaggs, B.; Chaturvedi, V.; Espinel-Ingroff, A.; Pfaller, M. A.; Rennie, R.; Rinaldi, M. G.; Walsh, T. J.

    2006-01-01

    The Clinical and Laboratory Standards Institute (CLSI; formerly National Committee for Clinical Laboratory Standards, or NCCLS) M38-A standard for the susceptibility testing of filamentous fungi does not specifically address the testing of dermatophytes. In 2003, a multicenter study investigated the reproducibility of the microdilution method developed at the Center for Medical Mycology, Cleveland, Ohio, for testing the susceptibility of dermatophytes. Data from that study supported the introduction of this method for testing dermatophytes in the future version of the CLSI M38-A standard. In order for the method to be accepted by CLSI, appropriate quality control isolates needed to be identified. To that end, an interlaboratory study, involving the original six laboratories plus two additional sites, was conducted to evaluate potential candidates for quality control isolates. These candidate strains included five Trichophyton rubrum strains known to have elevated MICs to terbinafine and five Trichophyton mentagrophytes strains. Antifungal agents tested included ciclopirox, fluconazole, griseofulvin, itraconazole, posaconazole, terbinafine, and voriconazole. Based on the data generated, two quality control isolates, one T. rubrum isolate and one T. mentagrophytes isolate, were identified and submitted to the American Type Culture Collection (ATCC) for inclusion as reference strains. Ranges encompassing 95.2 to 97.9% of all data points for all seven drugs were established. PMID:17050812

  4. Investigation of Microbiological Test Quality Control on Rat and Mouse%大、小鼠微生物检测质量控制探讨

    Institute of Scientific and Technical Information of China (English)

    白冰; 张海; 毛峰峰; 赵勇; 张彩勤; 赵善民; 师长宏

    2012-01-01

    The quality of lab animal affected the correct of research data directly, we could control the quality of lab animal through microbiological test regularly, so the microbiological test quality control was the effective and necessary way to manage and supervise daily. We summarized the experiences for the past few years, then we investigated the quality control work to provide some data for lab animal microbiological test.%实验动物质量直接影响科研数据的准确性,通过定期微生物检测,可对实验动物质量进行控制,因此对检测结果进行质量控制是对检测工作进行日常管理和监督的有效和必要的手段.实验室通过总结近年检测工作经验,对微生物检测质量控制工作进行探讨,为实验动物质量检测提供相关资料.

  5. Test Control Center

    Science.gov (United States)

    2000-01-01

    At the test observation periscope in the Test Control Center exhibit in StenniSphere at the John C. Stennis Space Center in Hancock County, Miss., visitors can observe a test of a Space Shuttle Main Engine exactly as test engineers might see it during a real engine test. The Test Control Center exhibit exactly simulates not only the test control environment, but also the procedure of testing a rocket engine. Designed to entertain while educating, StenniSphere includes informative dispays and exhibits from NASA's lead center for rocket propulsion and remote sensing applications. StenniSphere is open free of charge from 9 a.m. to 5 p.m. daily.

  6. [Quality control in parasitology].

    Science.gov (United States)

    Vasallo Matilla, F

    2001-01-01

    Between 1990 and 1996 we coordinated a Quality Control (QC) Program in Parasitology directed to Public Health Institutions in Spain. Periodically, parasited specimens, mainly feces or blood, were sent to Microbiology Laboratories for identification. Each QC was accompanied by a short clinic and epidemiological information in order to help in the diagnostic approach. After the answers to the QC were received a bulletin that included the solution to the QC, comments on the several answers received and a chapter with parasitological themes related with the QC, was sent to each participating Laboratory. The bulletin was accompanied by a card that included a photograph and a short description of the organism object of the QC.

  7. Establishment of a new quality control and vaccine safety test for influenza vaccines and adjuvants using gene expression profiling.

    Science.gov (United States)

    Momose, Haruka; Mizukami, Takuo; Kuramitsu, Madoka; Takizawa, Kazuya; Masumi, Atsuko; Araki, Kumiko; Furuhata, Keiko; Yamaguchi, Kazunari; Hamaguchi, Isao

    2015-01-01

    We have previously identified 17 biomarker genes which were upregulated by whole virion influenza vaccines, and reported that gene expression profiles of these biomarker genes had a good correlation with conventional animal safety tests checking body weight and leukocyte counts. In this study, we have shown that conventional animal tests showed varied and no dose-dependent results in serially diluted bulk materials of influenza HA vaccines. In contrast, dose dependency was clearly shown in the expression profiles of biomarker genes, demonstrating higher sensitivity of gene expression analysis than the current animal safety tests of influenza vaccines. The introduction of branched DNA based-concurrent expression analysis could simplify the complexity of multiple gene expression approach, and could shorten the test period from 7 days to 3 days. Furthermore, upregulation of 10 genes, Zbp1, Mx2, Irf7, Lgals9, Ifi47, Tapbp, Timp1, Trafd1, Psmb9, and Tap2, was seen upon virosomal-adjuvanted vaccine treatment, indicating that these biomarkers could be useful for the safety control of virosomal-adjuvanted vaccines. In summary, profiling biomarker gene expression could be a useful, rapid, and highly sensitive method of animal safety testing compared with conventional methods, and could be used to evaluate the safety of various types of influenza vaccines, including adjuvanted vaccine.

  8. Quality control of seasonal influenza vaccines.

    Science.gov (United States)

    Mandušić Nazor, Tamara; Pipić Kosanović, Marta; Tomić, Siniša

    2010-12-01

    The purpose of seasonal influenza vaccination is to prevent its spread. The vaccines contain strains of the influenza virus recommended and approved for a particular season. Just like any other medicinal product, all vaccines require marketing approval. Batches of approved vaccines are extensively tested by the manufacturers and additionally controlled by the approving authorities, which issue the quality control certificates. This article not only to describes the legal background of quality control, but also how control test results obtained by a Croatian official control laboratory are compared to manufacturer's results. We have found that testing results can slightly differ depending on methods/analytical procedures used in different laboratories. This investigation has also shown how important it is to test finished medicinal products, independently of testing at intermediate stages, and how retesting by control authorities ensures that marketed vaccines meet quality standards.

  9. First evaluation after implementation of a quality control system for the second line drug susceptibility testing of Mycobacterium tuberculosis joint efforts in low and high incidence countries.

    Directory of Open Access Journals (Sweden)

    Doris Hillemann

    Full Text Available Three networks/projects involving 27 European countries were established to investigate the quality of second-line drug (SLD susceptibility testing with conventional and molecular methods. 1. The "Baltic-Nordic TB-Laboratory Network" comprised 11 reference laboratories in the Baltic-Nordic States. They performed SLD testing in the first phase with a panel of 20 Mycobacterium tuberculosis strains. After several laboratories made technical changes a second panel of 10 strains with a higher proportion of resistant strains were tested. Although the concordance for Ofloxacin, Kanamycin, and Capreomycin was consistently high, the largest improvements in performance were achieved for the analysis of Ofloxacin resistant (from 88.9 to 95.0%, and Capreomycin resistant (from 71.0 to 88.9% strains. 2. Within the FP7 TB PAN-NET project (EU Grant agreement 223681 a quality control panel to standardize the EQA (External Quality Assurance for first-line drugs (FLD and SLD testing for phenotypic and molecular methods was established. The strains were characterized by their robustness, unambiguous results when tested, and low proportion of secondary drug resistances. 3. The (European Reference Laboratory Network-TB ERLN-TB network analyzed four different panels for drug resistance testing using phenotypic and molecular methods; in two rounds in 2010 the 31 participating laboratories began with 5 strains, followed by 10 strains and 6 additional crude DNA extracts in 2011 and 2012 were examined by conventional DST and molecular methods. Overall, we demonstrated the importance of developing inter-laboratory networks to establish quality assurance and improvement of SLD testing of M. tuberculosis.

  10. Quality assurance and quality control in clinical cytogenetics.

    Science.gov (United States)

    Mikhail, Fady M; Watson, Michael S

    2014-07-14

    The goal of any clinical laboratory should be to provide patients with the most accurate test results possible. This is accomplished through various overlapping programs that continuously monitor and optimize all aspects of a test, including decisions by the laboratory to offer a test, the decision of providers to request the test, the testing itself, and the reporting of results to the referral source and patient. The levels at which test performance and accuracy can be optimized are encompassed under quality control (QC) and quality assurance (QA). The monitoring of QC and QA problems allows for the integration of these parameters into a total quality management program. This unit reviews QC and QA guidelines, in addition to discussing how to establish a quality assurance program.

  11. 微生物检验实验室质量控制%Laboratory quality control of microbiological testing

    Institute of Scientific and Technical Information of China (English)

    黄顺贤

    2016-01-01

    Microorganisms are ubiquitous in human life,and it brings a lot of benefits to human beings,at the same time,it also brings a lot of harm.At present.Infectious diseases are still the main factors that cause the death of human beings,therefore,it is very important to study the microorganism,especially the pathogenic microorganism.This paper focuses on the quality control of clinical microbiology laboratory.%微生物在人类生活中,无处不在,它给人类带来很多益处的同时,也带来了很多的害处。当今传染病仍是引起人类死亡的主要因素,因此对微生物的研究,特别是对病原微生物的研究至关重要。本文重点讲述临床微生物检验的实验室质量控制。

  12. The effectiveness of computer reminders for improving quality assessment for point-of-care testing in general practice - a randomized controlled trial

    DEFF Research Database (Denmark)

    Kousgaard, Marius Brostrøm; Siersma, Volkert Dirk; Reventlow, Susanne

    2013-01-01

    for improving adherence to a quality assessment scheme for point-of-care testing in general practice. METHOD: The study was conducted as a randomized controlled crossover trial among general practices in the Capital Region of Denmark. The intervention consisted of sending computer reminders (Com......Rem) to practices not adhering to the guideline recommendations of split testing for hemoglobin and glucose. Practices were randomly allocated into two groups. During the first follow-up period, one of the groups received the ComRem intervention together with the general implementation activities (GIA), while......BACKGROUND: Computer reminders are increasingly being applied in efforts to improve quality and patient safety. However, research is still needed to establish the effectiveness of different kinds of reminders in various settings. This study aimed to evaluate the effectiveness of computer reminders...

  13. Posttranslational modification and quality control.

    Science.gov (United States)

    Wang, Xuejun; Pattison, J Scott; Su, Huabo

    2013-01-18

    Protein quality control functions to minimize the level and toxicity of misfolded proteins in the cell. Protein quality control is performed by intricate collaboration among chaperones and target protein degradation. The latter is performed primarily by the ubiquitin-proteasome system and perhaps autophagy. Terminally misfolded proteins that are not timely removed tend to form aggregates. Their clearance requires macroautophagy. Macroautophagy serves in intracellular quality control also by selectively segregating defective organelles (eg, mitochondria) and targeting them for degradation by the lysosome. Inadequate protein quality control is observed in a large subset of failing human hearts with a variety of causes, and its pathogenic role has been experimentally demonstrated. Multiple posttranslational modifications can occur to substrate proteins and protein quality control machineries, promoting or hindering the removal of the misfolded proteins. This article highlights recent advances in posttranslational modification-mediated regulation of intracellular quality control mechanisms and its known involvement in cardiac pathology.

  14. General aviation fuel quality control

    Science.gov (United States)

    Poitz, H.

    1983-01-01

    Quality control measures for aviation gasoline, and some of the differences between quality control on avgas and mogas are discussed. One thing to keep in mind is that with motor gasoline you can always pull off to the side of the road. It's not so easy to do in an airplane. Consequently, there are reasons for having the tight specifications and the tight quality control measures on avgas as compared to motor gasoline.

  15. 麻醉机质量控制检测与结果的分析%Analysis of quality control testing and results of the anesthesia machine

    Institute of Scientific and Technical Information of China (English)

    黄韬; 崔骊; 李向东; 云庆辉

    2013-01-01

    目的:通过对麻醉机的质量控制检测,分析造成麻醉机不合格的主要原因,并采取相应措施确保麻醉机的安全使用。方法:使用美国VT-PLUS-HF气流分析仪对医院麻醉机定期检测,并利用检测结果对麻醉机的质量状况进行统计分析,评估不合格因素。结果:通过对医院麻醉机定期检测和分析检测结果,采取相应的方法消除了多台麻醉机的安全隐患,保障其使用安全。结论:麻醉机的质量控制检测工作是医疗安全的重要组成部分,通过检测能够及时发现和消除麻醉机的安全隐患,确保患者的生命安全。%Objective:Though the result study of quality control testing of anesthesia machine by 4 yesrs, the factors to anesthesia machine failure is investigated, and the proposal of improving the quality of the equipment testing standards is given. Methods:Statistical analysis the quality of the anesthesia machines using the VT-PLUS-HF gas analyzers with U.S.FLUKE Corporation is used, the test results can be to assess the quality of the anesthesia machine fail factors. Results: Through regular detection, not only can anesthesia machine potential risk be eliminated but also quality safety of clinical use will be safeguarded. Conclusion: Quality control detection to anesthesia machine is an important component of medical safety. It concluded that detect the anesthesia machine security risks by quality controls, ensure the life safety of patients.

  16. Quality control tests of lab-reared Cydia pomonella and Cactoblastis cactorum field performance: Comparison of laboratory and field bioassays.

    Science.gov (United States)

    Research, operational, and commercial programs which rely on mass-reared insects of high quality and performance, need accurate methods for monitoring quality degradation during each step of production, handling and release. With continued interest in the use of the sterile insect technique (SIT) a...

  17. Quality control in gastrointestinal surgery.

    Science.gov (United States)

    Ramírez-Barba, Ector Jaime; Arenas-Moya, Diego; Vázquez-Guerrero, Arturo

    2011-01-01

    We analyzed the Mexican legal framework, identifying the vectors that characterize quality and control in gastrointestinal surgery. Quality is contemplated in the health protection rights determined according to the Mexican Constitution, established in the general health law and included as a specific goal in the actual National Development Plan and Health Sector Plan. Quality control implies planning, verification and application of corrective measures. Mexico has implemented several quality strategies such as certification of hospitals and regulatory agreements by the General Salubrity Council, creation of the National Health Quality Committee, generation of Clinical Practice Guidelines and the Certification of Medical Specialties, among others. Quality control in gastrointestinal surgery must begin at the time of medical education and continue during professional activities of surgeons, encouraging multidisciplinary teamwork, knowledge, abilities, attitudes, values and skills that promote homogeneous, safe and quality health services for the Mexican population.

  18. Investigation of the contribution possibilities of non-destructive methods of testing for the diagnosis and quality control of building materials with emphasis given on sustainable construction

    Science.gov (United States)

    Katsiotis, Nikolaos S.; Matikas, Theodoros E.; Moropoulou, Antonia

    2012-04-01

    In this work, the contribution potential of non-destructive methods of testing is studied in order to assess, diagnose and assert building materials' diagnosis & quality control, with emphasis given on Sustainable Construction. To this end, the following techniques are implemented: fiber-optics microscopy, digital image processing, scanning electron microscopy, pulse/lock-in thermography, acoustic emission as well as ultrasounds. Furthermore, in addition to the above, the maturity method for measurement of compressive strength is applied and correlated to the array of full field non-destructive methods of testing. The results of the study clearly demonstrate how effective non-destructive methods of testing can be, in revealing and determining highly applicable data in a real-time, in situ and efficient manner.

  19. Indoor Quality Control Rules for Routine Clinical Biochemical Tests%临床常规生化项目室内质控方法的设计

    Institute of Scientific and Technical Information of China (English)

    郑强

    2015-01-01

    Objective To study the indoor quality control rules for routine clinical biochemical tests. Methods Quality control indexes of Alkaline phosphatase (ALKP), potassium (K) and calcium (Ca) from July to December 2012 were collected. The accumulative coefficient of variation (CA) of indoor quality control was used as imprecision degree;bias was calculated using external quality assessment of Clinical Laboratory Center of Chinese Ministry of Public Health;total error al-lowance was evaluated using proficiency testing in American Clinical Laboratory Improvement Amendments 88 (CLIA'88). The feasible indoor quality control methods were made based on operational process of specification chart so as to improve the prob-ability for error detection (Ped) and reduce the probability for false rejection (Pfr). Results The measured value of each batch control number was 2, and ALKP and K were chosen for 1-3 s as quality control rule in order to achieve Ped above 90%and Pfr below 5%;however, the measured value of each batch control number was 4, and Ca was chosen for 1-3 s/2-2 s/R-4 s/4-1 s/12-X as quality control rule in order to achieve Ped above 90% and Pfr below 5%. Conclusion Different biochem-ical analysis projects should select different control rules based on the different performance characteristics of analytical methods.%目的:探讨保证临床质量要求的常规生化项目室内质控规则的设计。方法收集2012年7—12月碱性磷酸酶(ALKP)、钾、钙的质控数据,以室内质控的累积变异系数(CV)作为项目的不精密度,应用卫生部临床检验中心室间质评结果计算偏倚,选择美国临床实验室改进修正法规88能力比对检验评价限为总允许误差,借助操作过程规范图设计符合本实验室切实可行的室内质控方法,从而提高误差检出概率( Ped),降低假失控概率( Pfr)。结果ALKP、钾每天测定质控品个数为2,选择1-3 s单质控规则即可满足Ped>90%,Pfr90%,Pfr<5%。结论

  20. Development and evaluation of Standard Operating Procedures (SOPs) for quality control tests and radiological protection activities in a Nuclear Medicine Service

    Energy Technology Data Exchange (ETDEWEB)

    Krempser, Alexandre R., E-mail: krempser@peb.ufrj.br [Universidade Federal do Rio de Janeiro (PEB/COPPE/UFRJ), RJ (Brazil). Programa de Engenharia Biomedica; Soares, Alexandre B. [Universidade Federal do Rio de Janeiro (IF/UFRJ), Rio de Janeiro, RJ (Brazil). Inst. de Fisica; Corbo, Rossana [Universidade Federal do Rio de Janeiro (FM/UFRJ), Rio de Janeiro, RJ (Brazil). Dept. de Radiologia

    2011-07-01

    The quality management in Nuclear Medicine Services is a requirement of national and international standards. The Brazilian regulatory agency in health surveillance, the Agencia Nacional de Vigilancia Sanitaria (ANVISA), in its Resolucao de Diretoria Colegiada (Collegiate Directory Resolution) no. 38, requires the elaboration of documents describing the technical and clinical routine activities. This study aimed to elaborate, implement and evaluate Standard Operating Procedures (SOPs) for quality control tests and radiological protection activities in the Nuclear Medicine Service of a university hospital. Eighteen SOPs were developed, involving tasks related to dose calibrator, gamma camera, Geiger-Muller detectors and radiological protection activities. The performance of its application was evaluated for a period of six months. It was observed a reduction in 75% of reported operational errors and 42% of the number of reported incidents with contamination by radioactive material. The SOPs were adequate and successful in its application. New procedures involving clinical activities will also be developed and evaluated. (author)

  1. Flying qualities criteria and flight control design

    Science.gov (United States)

    Berry, D. T.

    1981-01-01

    Despite the application of sophisticated design methodology, newly introduced aircraft continue to suffer from basic flying qualities deficiencies. Two recent meetings, the DOD/NASA Workshop on Highly Augmented Aircraft Criteria and the NASA Dryden Flight Research Center/Air Force Flight Test Center/AIAA Pilot Induced Oscillation Workshop, addressed this problem. An overview of these meetings is provided from the point of view of the relationship between flying qualities criteria and flight control system design. Among the items discussed are flying qualities criteria development, the role of simulation, and communication between flying qualities specialists and control system designers.

  2. Frontiers in statistical quality control

    CERN Document Server

    Wilrich, Peter-Theodor

    2004-01-01

    This volume treats the four main categories of Statistical Quality Control: General SQC Methodology, On-line Control including Sampling Inspection and Statistical Process Control, Off-line Control with Data Analysis and Experimental Design, and, fields related to Reliability. Experts with international reputation present their newest contributions.

  3. Application of QC_DR software for acceptance testing and routine quality control of direct digital radiography systems: initial experiences using the Italian Association of Physicist in Medicine quality control protocol.

    Science.gov (United States)

    Nitrosi, Andrea; Bertolini, Marco; Borasi, Giovanni; Botti, Andrea; Barani, Adriana; Rivetti, Stefano; Pierotti, Luisa

    2009-12-01

    Ideally, medical x-ray imaging systems should be designed to deliver maximum image quality at an acceptable radiation risk to the patient. Quality assurance procedures are employed to ensure that these standards are maintained. A quality control protocol for direct digital radiography (DDR) systems is described and discussed. Software to automatically process and analyze the required images was developed. In this paper, the initial results obtained on equipment of different DDR manufacturers were reported. The protocol was developed to highlight even small discrepancies in standard operating performance.

  4. Access Control Enforcement Testing

    OpenAIRE

    El Kateb, Donia; Elrakaiby, Yehia; Mouelhi, Tejeddine; Le Traon, Yves

    2012-01-01

    A policy-based access control architecture com- prises Policy Enforcement Points (PEPs), which are modules that intercept subjects access requests and enforce the access decision reached by a Policy Decision Point (PDP), the module implementing the access decision logic. In applications, PEPs are generally implemented manually, which can introduce errors in policy enforcement and lead to security vulnerabilities. In this paper, we propose an approach to systematically test and validate the co...

  5. [Quality control of plant extract].

    Science.gov (United States)

    Shao, Yun-dong; Gao, Wen-yuan; Liu, Dan; Jia, Wei; Duan, Hong-Quan; Zhang, Tie-jun

    2003-10-01

    The current situation of plant extract in domestic and international market was analyzed in the paper. The quality control of 20 plant extracts which have reasonably good sales in USA market was compared and analyzed. The analysis of the quality control of six plant extracts indicated that there were two main reasons leading to the varied quality specifications among different suppliers. One reason was that the plant species utilized by different companies were different. The other reason was that the extraction processes were different among different production plants. Comparing with the significant international suppliers of plant extracts, the product quality of Chinese companies were not satisfactory. It was suggested that chromatography and chromatographic fingerprint techniques should be applied to improve the quality control standard of plant extract in our country.

  6. Quality control ranges for testing broth microdilution susceptibility of Flavobacterium columnare and F. psychrophilum to nine antimicrobials

    DEFF Research Database (Denmark)

    Gieseker, Charles M.; Mayer, Tamara D.; Crosby, Tina C.

    2012-01-01

    . These data and their associated QC ranges have been approved by the Clinical and Laboratory Standards Institute (CLSI), and will be included in the next edition of the CLSI M49-A Guideline. This method represents the first standardized reference method for testing fish pathogenic Flavobacterium spp....

  7. SAQC: SNP Array Quality Control

    Directory of Open Access Journals (Sweden)

    Li Ling-Hui

    2011-04-01

    Full Text Available Abstract Background Genome-wide single-nucleotide polymorphism (SNP arrays containing hundreds of thousands of SNPs from the human genome have proven useful for studying important human genome questions. Data quality of SNP arrays plays a key role in the accuracy and precision of downstream data analyses. However, good indices for assessing data quality of SNP arrays have not yet been developed. Results We developed new quality indices to measure the quality of SNP arrays and/or DNA samples and investigated their statistical properties. The indices quantify a departure of estimated individual-level allele frequencies (AFs from expected frequencies via standardized distances. The proposed quality indices followed lognormal distributions in several large genomic studies that we empirically evaluated. AF reference data and quality index reference data for different SNP array platforms were established based on samples from various reference populations. Furthermore, a confidence interval method based on the underlying empirical distributions of quality indices was developed to identify poor-quality SNP arrays and/or DNA samples. Analyses of authentic biological data and simulated data show that this new method is sensitive and specific for the detection of poor-quality SNP arrays and/or DNA samples. Conclusions This study introduces new quality indices, establishes references for AFs and quality indices, and develops a detection method for poor-quality SNP arrays and/or DNA samples. We have developed a new computer program that utilizes these methods called SNP Array Quality Control (SAQC. SAQC software is written in R and R-GUI and was developed as a user-friendly tool for the visualization and evaluation of data quality of genome-wide SNP arrays. The program is available online (http://www.stat.sinica.edu.tw/hsinchou/genetics/quality/SAQC.htm.

  8. Validation Test Report for the NRL Ocean Surface Flux (NFLUX) Quality Control and 2D Variational Analysis System

    Science.gov (United States)

    2014-06-11

    Xu et al., 2011). The eastern Pacific test case represents a basin area with frequent winter storms (e.g. Graham and Diaz, 2001) and persistent...heights are nominally at 5m. Ship measurement heights vary from 10 m to 40 m ( Kent et al., 2007). When possible, we height-adjust ship measurements to 5...before, the north Pacific is known for frequent storm tracks year round, with the peak in storm activity from December through March ( Graham and Diaz

  9. Quality of HIV laboratory testing in Tanzania: a situation analysis.

    Science.gov (United States)

    Mfinanga, G S; Mutayoba, B; Mbogo, G; Kahwa, A; Kimaro, G; Mhame, P P; Mwangi, C; Malecela, M N; Kitua, A Y

    2007-01-01

    Tanzania is scaling up prevention, treatment, care and support of individuals affected with HIV. There is therefore a need for high quality and reliable HIV infection testing and AIDS staging. The objective of this study was to assess laboratories capacities of services in terms of HIV testing and quality control. A baseline survey was conducted from December 2004 to February 2005 in 12 laboratories which were conveniently selected to represent all the zones of Tanzania. The questionnaires comprised of questions on laboratory particulars, internal and external quality control for HIV testing and quality control of reagents. Source and level of customer satisfaction of HIV test kits supply was established. Of 12 laboratories, nine used rapid tests for screening and two used rapid tests for diagnosis. In the 12 laboratories, four used double ELISA and five used single ELISA and three did not use ELISA. Confirmatory tests observed were Western Blot in three laboratories, DNA PCR in two laboratories, CD4 counting in seven laboratories, and viral load in two laboratories. Although all laboratories conducted quality control (QC) of the HIV kits, only two laboratories had Standard Operating Procedures (SOPs). Internal and external quality control (EQC) was done at varied proportions with the highest frequency of 55.6% (5/9) for internal quality control (IQC) for rapid tests and EQC for ELISA, and the lowest frequency of 14.3% (1/ 7) for IQC for CD4 counting. None of the nine laboratories which conducted QC for reagents used for rapid tests and none of the five which performed IQC and EQC had SOPs. HIV kits were mainly procured by the Medical Store Department and most of laboratories were not satisfied with the delay in procurement procedures. Most of the laboratories used rapid tests only, while some used both rapid tests and ELISA method for HIV testing. In conclusion, the survey revealed inadequacy in Good Laboratory Practice and poor laboratory quality control process

  10. Quality Control and Testing Methods of Infusion Apparatus%输液设备的质量控制和检测方法

    Institute of Scientific and Technical Information of China (English)

    侯明扬

    2014-01-01

    根据输液设备质量检测规范,利用FULK测量设备分别对输液泵和注射泵的外观、流量、阻塞报警压力阈值、监测与报警系统进行检测,并对各个参数的检测方法与标准做了详细介绍,为医学工程人员进行输液设备的质控工作提供参考。%According to the quality inspection speciifcations of infusion apparatus, the appearance, lfow, pressure threshold value of blocking alarm and monitoring and alarm system of infusion pump and injection pump were tested by using FULK measuring equipment. This paper also introduced the testing methods and standards of various parameters in order to provide reference information for medical engineering staff to improve the quality control of infusion apparatus.

  11. 10 CFR 71.123 - Test control.

    Science.gov (United States)

    2010-01-01

    ... 10 Energy 2 2010-01-01 2010-01-01 false Test control. 71.123 Section 71.123 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) PACKAGING AND TRANSPORTATION OF RADIOACTIVE MATERIAL Quality Assurance § 71.123 Test control. The licensee, certificate holder, and applicant for a CoC shall establish a...

  12. 临床微生物检验质量控制研究%The Research on Quality Control of Clinical Microbiology Test

    Institute of Scientific and Technical Information of China (English)

    刘静杰

    2015-01-01

    在人类生存环境中,有较多的微生物种类,而且很多泛耐药菌和多重耐药菌,可对感染性疾病在治疗时产生一定的阻碍作用,加强控制微生物的检验质量,并针对存在的问题提出相应的改进措施,积极推动临床医学的发展,本文主要对微生物的质量控制进行相关研究。%There is a diversity of microbiology in the living environments of human beings,and many Pan-resistant strains and multi-drug resistant bacteria exert a negative influence on treatment of infectious disease. Strengthen the quality control of microbiology test and put forward approaches to solve the existing problems in order to facilitate developments of clinical medicine science. This paper is mainly about the research on quality control of microbiology.

  13. Pursuing the Qualities of a "Good" Test

    Science.gov (United States)

    Coniam, David

    2014-01-01

    This article examines the issue of the quality of teacher-produced tests, limiting itself in the current context to objective, multiple-choice tests. The article investigates a short, two-part 20-item English language test. After a brief overview of the key test qualities of reliability and validity, the article examines the two subtests in terms…

  14. Quality control in exascale data archives

    Science.gov (United States)

    Juckes, Martin

    2013-04-01

    Quality control of data can and should occur at many stages of the data life cycle. Data producers will generally conduct their own tests prior to release of data. Further tests may be done by within consortium projects, by archive centres or, after publication of the data, by independent investigators. The results of such tests are often used only by the individual or group carrying out the tests. Sharing of quality control information is restricted by many factors: this presentation addresses the lack of a common terminology to define quality control tests. A framework is proposed, based on abstract tests (e.g. a "prescribed range test"), specific tests (e.g. "variable tas is in the range 200-350K") and test results. Test results also need to be linked to the data robustly to ensure that they are available at all subsequent stages of the data lifecycle, and the appropriate mechanisms of linkage will differ at different stages of the lifecycle. The framework should support references to the data from the test results, references to the results from the data or discovery by association. Performing tests may generate useful by-products (e.g. the maximum and minimum values of the data): these ancillary results should be stored and made accessible with test results. In many cases tests will refer to multiple files, and groups of tests will be of more interest than individual tests. Mechanisms for describing tests suites will be discussed with particular reference to the challenges of applying tests to climate model data.

  15. Frontiers in statistical quality control

    CERN Document Server

    Wilrich, Peter-Theodor

    2001-01-01

    The book is a collection of papers presented at the 5th International Workshop on Intelligent Statistical Quality Control in Würzburg, Germany. Contributions deal with methodology and successful industrial applications. They can be grouped in four catagories: Sampling Inspection, Statistical Process Control, Data Analysis and Process Capability Studies and Experimental Design.

  16. HPLC for quality control of polyimides

    Science.gov (United States)

    Young, P. R.; Sykes, G. F.

    1979-01-01

    High Pressure Liquid Chromatography (HPLC) as a quality control tool for polyimide resins and prepregs are presented. A data base to help establish accept/reject criteria for these materials was developed. This work is intended to supplement, not replace, standard quality control tests normally conducted on incoming resins and prepregs. To help achieve these objectives, the HPLC separation of LARC-160 polyimide precursor resin was characterized. Room temperature resin aging effects were studied. Graphite reinforced composites made from fresh and aged resin were fabricated and tested to determine if changes observed by HPLC were significant.

  17. HPLC for quality control of polyimides

    Science.gov (United States)

    Young, P. R.; Sykes, G. F.

    1979-01-01

    High Pressure Liquid Chromatography (HPLC) as a quality control tool for polyimide resins and prepregs are presented. A data base to help establish accept/reject criteria for these materials was developed. This work is intended to supplement, not replace, standard quality control tests normally conducted on incoming resins and prepregs. To help achieve these objectives, the HPLC separation of LARC-160 polyimide precursor resin was characterized. Room temperature resin aging effects were studied. Graphite reinforced composites made from fresh and aged resin were fabricated and tested to determine if changes observed by HPLC were significant.

  18. 2008年全国自身抗体检测质量控制总结%Summary of the 2008 national autoantibody testing quality control

    Institute of Scientific and Technical Information of China (English)

    李秋霞; 魏秋静; 李齐光; 古洁若

    2010-01-01

    目的 了解我国自身抗体检测的现状,进一步规范和提高我国自身抗体检测的水平.方法 以自愿报名的方法确定参与单位.质量控制项同包括抗核抗体(ANA)、抗双链DNA(dsDNA)抗体、抗可提取核抗原(ENA)抗体、抗线粒体抗体(AMA)/抗平滑肌抗体(ASMA)和抗环瓜氨酸肽(CCP)抗体5项,共15份标本.标本发放及结果分析采用双盲操作.结果 共102家医院或科室参加质量控制活动.ANA、抗dsDNA抗体、AMA、ASMA和抗CCP抗体的正确率分别为70%、88%、93%、85%和79%;抗RNP抗体、抗Sm抗体、抗SSA抗体、抗SSB抗体和抗Scl-70 正确率分别为88%、77%、92%、93%和87%.结论 我国自身抗体检测情况与前4次质鼍控制相比,参与质量控制的医院和检测的项目逐年增多,ANA、抗dsDNA抗体、抗ENA抗体和AMA检测水平降低,而ASMA和抗CCP抗体检测水平有所提高.%Objective To consecutively understand the national clinical testing status and to reassure the quality-control of autoantibody detection. Methods Letter or telephone notification were conducted to the participating hospitals or departments. Autoantibodies for quality control survey included anti-nuclear anti-body (ANA), anti-double-stranded DNA (anti-dsDNA), anti-extractable nuclear antigens (A-ENA), anti-mitochondria antibody (AMA)/anti-smooth muscle antibody (ASMA), and anti-citrulline antibody (anti-CCP). Each had 3 control samples, and altogether 15 samples for testing. Sample distribution and data analysis were double-blinded. Results One hundred and two hospitals/departments participated in the national quality-control survey. The accurate rate for this survey was 70%, 88%, 93%, 85%, 79% respectively for ANA, anti-dsDNA, AMA, ASMA and anti-CCP. Anti-ENAs were further divided into anti-RNP, Sm, SSA, SSB and Scl-70 subgroups, and the accurate rate was 88%, 77%, 92%, 93% and 87% respectively. Conclu-sion Compared to the previous 4 national surveys, the accurate rates of

  19. Discussing Interior Quality Control Method of ELISA Qualitative Test%ELISA法定性试验室内质控方法探讨

    Institute of Scientific and Technical Information of China (English)

    丁海明; 潘婉仪

    2011-01-01

    Objective To discuss ELISA qualitative test inside quality control method. Methods Detected HBsAg,HBsAb,HBeAg,HBeAb and HBcAb of weakly positive oc matter and 900 patients serum by ELISA method,analyse QC data with Levey-Jennings and half hold range method. Results 25 patients serum in 900 patients serum appeared false-negative and false-positive alone utilize Levey-Jennings QC map. Conclusion Combine Levey-Jennings oc map and half hold range method wben utilize ELISA qualitative test interior quality control method,reasonable choose fit experimental QC method by experimentation purpose.%目的 探讨ELISA法定性试验室内质控方法.方法 以ELISA法检测弱阳性质控品和900份病人血清的HBsAg,HBsAb,HBeAg,HBeAb和HBcAb,用Levey-Jennings质控图法和半固定范围法分别分析质控数据.结果 单独应用Levey-Jennings质控图法时,900份血清中有25份标本阴阳性出现误判.结论 在应用ELISA法定性试验室内质控方法时,结合Levey-Jennings质控图法和半固定范围法,根据实验目的合理选择适合各实验的质控方法.

  20. A step forward in the quality control testing of inactivated rabies vaccines - extensive evaluation of European vaccines by using alternative methods to the in vivo potency tests.

    Science.gov (United States)

    Servat, Alexandre; Kempff, Sébastien; Brogat, Valère; Litaize, Estelle; Schereffer, Jean-Luc; Cliquet, Florence

    2015-03-01

    The mouse challenge test still remains the reference method for the potency determination of human and animal inactivated rabies vaccines, and it is still widely used throughout the world. This test suffers from many disadvantages - it is expensive and time consuming, uses a large number of mice, causes significant animal distress, and suffers from high variability. Recently, the European Pharmacopoeia has recognised the use of a serological potency assay (SPA) as an alternative method to the challenge test. This new test is based on the determination of rabies neutralising antibody titres in vaccinated mice, by using the modified Rapid Fluorescent Focus Inhibition Test (mRFFIT). With the objective of adopting this new method for the batch release of inactivated rabies vaccines, we evaluated its performance on a large collection of rabies vaccines currently assessed in our laboratory. The Fluorescent Antibody Virus Neutralisation test (FAVNt) was used in parallel with the mRFFIT, and the results were compared to the mouse challenge test. Our results demonstrate that the SPA is capable of estimating the potency of vaccines formulated with a potency margin well above the minimum of 1IU/dose. For low potency vaccines, this new method demonstrated some limitations, due to the recurrent invalidation of the assay. We have also demonstrated the superior sensitivity of the FAVNt when compared to the mRFFIT, and the importance of minimising the risk of detecting non-responders in vaccinated mice. 2015 FRAME.

  1. Development of the control system of the ALICE transition radiation detector and of a test environment for quality-assurance of its front-end electronics

    Energy Technology Data Exchange (ETDEWEB)

    Mercado Perez, Jorge

    2008-11-10

    Within this thesis, the detector control system (DCS) for the Transition Radiation Detector (TRD) of the ALICE experiment at the Large Hadron Collider has been developed. The TRD DCS is fully implemented as a detector oriented hierarchy of objects behaving as finite state machines. It controls and monitors over 65 thousand front-end electronics (FEE) units, a few hundred low voltage and one thousand high voltage channels, and other sub-systems such as cooling and gas. Commissioning of the TRD DCS took place during several runs with ALICE using cosmic events. Another part of this thesis describes the development of a test environment for large-scale production quality-assurance of over 4 thousand FEE read-out boards containing in total about 1.2 million read-out channels. The hardware and software components are described in detail. Additionally, a series of performance studies were carried out earlier including radiation tolerance tests of the TRAP chip which is the core component of the TRD FEE. (orig.)

  2. 关于微生物检验质量控制的探讨%Discussion on quality control of microbiological testing

    Institute of Scientific and Technical Information of China (English)

    程小平

    2015-01-01

    科室感染会大大影响患者和医生、护士的身体健康,不利于患者康复。近年来,大量临床实践表明,微生物检验在感染控制当中的作用是比较大的。且随着微生物检验学科的快速发展,微生物检验质量控制工作变得越来越重要。%The department infection will be greatly affected the health of patients,doctors and nurses.It is not conducive to the rehabilitation of patients.In recent years,a large number of clinical practice showed that the role of microbial test in infection control is relatively large.With the rapid development of the microbial test subjects,microbiological quality control becomes more and more important.

  3. The application of quality control circle(QCC) in improving the basic quality of test%品管圈在提高基础检验质量中的应用

    Institute of Scientific and Technical Information of China (English)

    叶竞争; 叶儒军; 林一民

    2014-01-01

    Objective To study the significance of quality control circle(QCC)in improving the basic quality of test .Methods Using the management tool of QCC and selecting activity theme ,drawing up a plan of QCC to analyse fishbone diagram Plato and countermeasure ,investigating the basic quality confirming the effect ,finally comparing the change of basic quality of test after implementing QCC .Results After implementing QCC activity ,it was found that each index ,including the delay rate of the emergency examination report ,patients′satisfaction degree ,the receiving and registering specimens rate of emergency laboratory ,have been improved with significant difference(P< 0 .05);The ability of circle have been enhanced more than before .Conclusion The quality control circle(QCC)have in‐creased the basic quality of test and promoted the continual improvement of clinical examination .%目的:探讨品管圈(QCC)活动对于提高基础检验质量的意义。方法应用QCC管理工具,选定活动主题,制定品管圈活动计划,进行鱼骨图、柏拉图和对策分析、基础质量调查、效果确认,比较执行品管圈活动前后基础检验质量的变化。结果在施行QCC活动后,急诊检验报告延时率、患者满意度、急诊化验室窗口标本接收登记率等指标均差异有统计学意义(P<0.05);圈能力得到较大提高(P<0.05)。结论 QCC活动提高了基础检验质量,促进了临床检验工作的持续改进。

  4. Establishing quality control ranges for antimicrobial susceptibility testing of Escherichia coli, Pseudomonas aeruginosa, and Staphylococcus aureus: a cornerstone to develop reference strains for Korean clinical microbiology laboratories.

    Science.gov (United States)

    Hong, Sung Kuk; Choi, Seung Jun; Shin, Saeam; Lee, Wonmok; Pinto, Naina; Shin, Nari; Lee, Kwangjun; Hong, Seong Geun; Kim, Young Ah; Lee, Hyukmin; Kim, Heejung; Song, Wonkeun; Lee, Sun Hwa; Yong, Dongeun; Lee, Kyungwon; Chong, Yunsop

    2015-11-01

    Quality control (QC) processes are being performed in the majority of clinical microbiology laboratories to ensure the performance of microbial identification and antimicrobial susceptibility testing by using ATCC strains. To obtain these ATCC strains, some inconveniences are encountered concerning the purchase cost of the strains and the shipping time required. This study was focused on constructing a database of reference strains for QC processes using domestic bacterial strains, concentrating primarily on antimicrobial susceptibility testing. Three strains (Escherichia coli, Pseudomonas aeruginosa, and Staphylococcus aureus) that showed legible results in preliminary testing were selected. The minimal inhibitory concentrations (MICs) and zone diameters (ZDs) of eight antimicrobials for each strain were determined according to the CLSI M23. All resulting MIC and ZD ranges included at least 95% of the data. The ZD QC ranges obtained by using the CLSI method were less than 12 mm, and the MIC QC ranges extended no more than five dilutions. This study is a preliminary attempt to construct a bank of Korean QC strains. With further studies, a positive outcome toward cost and time reduction can be anticipated.

  5. Quality assurance and statistical control

    DEFF Research Database (Denmark)

    Heydorn, K.

    1991-01-01

    In scientific research laboratories it is rarely possible to use quality assurance schemes, developed for large-scale analysis. Instead methods have been developed to control the quality of modest numbers of analytical results by relying on statistical control: Analysis of precision serves...... serves to detect analytical bias by comparing results obtained by two different analytical methods, each relying on a different detection principle and therefore exhibiting different influence from matrix elements; only 5-10 sets of results are required to establish whether a regression line passes...

  6. Statistical analysis of concrete quality testing results

    Directory of Open Access Journals (Sweden)

    Jevtić Dragica

    2014-01-01

    Full Text Available This paper statistically investigates the testing results of compressive strength and density of control concrete specimens tested in the Laboratory for materials, Faculty of Civil Engineering, University of Belgrade, during 2012. The total number of 4420 concrete specimens were tested, which were sampled on different locations - either on concrete production site (concrete plant, or concrete placement location (construction site. To be exact, these samples were made of concrete which was produced on 15 concrete plants, i.e. placed in at 50 different reinforced concrete structures, built during 2012 by 22 different contractors. It is a known fact that the achieved values of concrete compressive strength are very important, both for quality and durability assessment of concrete inside the structural elements, as well as for calculation of their load-bearing capacity limit. Together with the compressive strength testing results, the data concerning requested (designed concrete class, matching between the designed and the achieved concrete quality, concrete density values and frequency of execution of concrete works during 2012 were analyzed.

  7. Validation of quality control tests of a multi leaf collimator using electronic portal image devices and commercial software; Validacion de unas pruebas de control de calidad del colimador multilamina utilizando dispositivos electronicos de imagen portal y una aplicacion comercial

    Energy Technology Data Exchange (ETDEWEB)

    Latorre-Musoll, A.; Jornet Sala, N.; Carrasco de Fez, P.; Edualdo Puell, T.; Ruiz Martinez, A.; Ribas Morales, M.

    2013-07-01

    We describe a daily quality control procedure of the multi leaf collimator (MLC) based on electronic portal image devices and commercial software. We designed tests that compare portal images of a set of static and dynamic MLC configurations to a set of reference images using commercial portal dosimetry software. Reference images were acquired using the same set of MLC configurations after the calibration of the MLC. To assess the sensitivity to detect MLC under performances, we modified the MLC configurations by inserting a range of leaf position and speed errors. Distance measurements on portal images correlated with leaf position errors down to 0.1 mm in static MLC configurations. Dose differences between portal images correlated both with speed errors down to 0.5% of the nominal leaf velocities and with leaf position errors down to 0.1 mm in dynamic MLC configurations. The proposed quality control procedure can assess static and dynamic MLC configurations with high sensitivity and reliability. (Author)

  8. Research and design a new model phantom for SPECT quality control testing%一种新型SPECT性能检测模体的研制

    Institute of Scientific and Technical Information of China (English)

    李红磊; 刘晓建; 杨昆; 李晓鸣; 姚树林; 杜国生

    2014-01-01

    Objective: To research and design a new model for SPECT quality control testing, which is consistent with the national standards of geometry and materials, and has a lot of advantages, including the optimized and reasonable structure, convenient to use, high efficiency, and little exposure dose for testing personnel. Methods: To investigate current international and domestic standard protocols for the purpose of confirming the key parameter; to optimize the design based on the characteristics of γradiation detection and prevention, and improve the capability of the available technologies. Results: The process of research and design includes:1. Lead Grid model, applied to test the“inherent spatial resolution”and“inherent spatial differential linearity”of the SPECT system, with one die body endowed with bidirectional application as X/Y;2. Dual Linear Source model, used to test“the system spatial resolution (mm)”and“the whole body spatial resolution (mm)”, as well as the“the system spatial resolution (mm)”of double detectors;3. Plane Source model, applied to the simultaneous test of“system plane sensitivity”of the double detectors;4. Holder of Radioactive Source with low scattering. 5. Others for connecting and supporting. 6. Data acquisition and analysis software. This new model has obtained 4 patent licenses. Conclusion:This new model is easy to use, highly effective. It could lessen the dosage of 99Tcm, reduce the radiation injury of personnel. In the future, we need improve the structure of model to reduce radiation dose further, and make a positioning standard for lead grid model during quality control detectingin China, and this work also lay the foundation for the further work in the quality control of the dental panoramic machine.%目的:研究设计一种几何尺寸、材料符合国家标准要求及结构优化合理的用于SPECT系统成像设备质量控制检测的新型模体。方法:调研国内外现有标准及模体

  9. Performance Testing and Quality Control of Biological Safety Cabinets%生物安全柜的性能检测与质量控制

    Institute of Scientific and Technical Information of China (English)

    赵伟

    2013-01-01

    Objective Through performance testing of biological safety cabinet,to understand its performance,so as to improve its safety.Methods Six required items are tested according to the standard of Biological Safety Cabinets.Results The six required items can meet the technical requirements,the biological safety cabinet is qualified.Conclusion Quality control of medical equipment is of great significance.%目的 通过对生物安全柜的性能检测,以掌握其性能现状,提高使用的安全性.方法 依据《生物安全柜》标准,对生物安全性等6个必检项目进行性能检测.结果 6个检测项目符合技术要求,生物安全柜性能合格.结论 加强医疗设备质量控制关系重大,不容忽视.

  10. Frontiers in statistical quality control

    CERN Document Server

    Wilrich, Peter-Theodor

    1997-01-01

    Like the preceding volumes, and met with a lively response, the present volume is collecting contributions stressed on methodology or successful industrial applications. The papers are classified under four main headings: sampling inspection, process quality control, data analysis and process capability studies and finally experimental design.

  11. Analysis on Problems and Measures of Indoor Quality Control of Blood Test%浅析血液检验室内质量控制面临的问题与措施

    Institute of Scientific and Technical Information of China (English)

    葛晓东

    2013-01-01

      目的分析血液检验室内质量控制面临的问题并探讨其应对措施。方法对检验科血液检验室内质量控制过程进行回顾性分析,从可能影响血液检验室内质量控制的方面出发,分析血液检验室内质量控制面临的问题并提出针对性的解决措施。结果血液检验室内质量控制存在人员素质、仪器工作环境、仪器鉴定和矫正、检测试剂、质控液的准备、质控方法及分析后质量控制等方面的问题。结论针对血液检验室内质量控制过程存在的问题给予相应的应对措施能在一定程度上提高室内质控质量,提高检测的准确性。%Objectives To analyze the problems of indoor quality control of bloodtest and to observe the measures. Methods Analyzing retrospectively the indoor quality control process of blood test in blood screening test department.And analyzing the problems of indoor quality control of blood test and promoting the solving measures from the aspects influencing the quality control in blood test chamber. Results Indoor quality control of blood test includes the problems below:the quality of personnel, instrument working environment, instrument identification and correction, detection reagent, quality control liquid preparation, quality control method and analysis of quality control. Conclusions Giving corresponding measures on problems of indoor quality control of blood test can improve the quality control and the accuracy of detection to a certain extent.

  12. Role of test in total quality management

    Science.gov (United States)

    Neblett, Bill

    1995-05-01

    The quality of a delivered product or system is ultimately limited by the quality of its design and manufacturing process. Defects that escape the design, manufacturing, and test processes are delivered to customers. Process Potential Index (Cp) and Process Capability Index (Cpk) are now widely used to express design and manufacturing quality. Design quality may be estimated from product models, if they exist, or measured using parameter test data. The difficulty in using test data is no so much in the calculations, but in the recording, storing, and selection of the data to be used in the calculations. This paper defines the metrics of quality estimation and describes an implementation of a system for estimating defect levels and process capabilities. The implementation includes the definition of a standardized parametric data exchange language for test data and an analytical system to standardize product quality measurement.

  13. A cluster randomized controlled trial aimed at implementation of local quality improvement collaboratives to improve prescribing and test ordering performance of general practitioners: Study Protocol

    Directory of Open Access Journals (Sweden)

    Winkens Ron

    2009-02-01

    Full Text Available Abstract Background The use of guidelines in general practice is not optimal. Although evidence-based methods to improve guideline adherence are available, variation in physician adherence to general practice guidelines remains relatively high. The objective for this study is to transfer a quality improvement strategy based on audit, feedback, educational materials, and peer group discussion moderated by local opinion leaders to the field. The research questions are: is the multifaceted strategy implemented on a large scale as planned?; what is the effect on general practitioners' (GPs test ordering and prescribing behaviour?; and what are the costs of implementing the strategy? Methods In order to evaluate the effects, costs and feasibility of this new strategy we plan a multi-centre cluster randomized controlled trial (RCT with a balanced incomplete block design. Local GP groups in the south of the Netherlands already taking part in pharmacotherapeutic audit meeting groups, will be recruited by regional health officers. Approximately 50 groups of GPs will be randomly allocated to two arms. These GPs will be offered two different balanced sets of clinical topics. Each GP within a group will receive comparative feedback on test ordering and prescribing performance. The feedback will be discussed in the group and working agreements will be created after discussion of the guidelines and barriers to change. The data for the feedback will be collected from existing and newly formed databases, both at baseline and after one year. Discussion We are not aware of published studies on successes and failures of attempts to transfer to the stakeholders in the field a multifaceted strategy aimed at GPs' test ordering and prescribing behaviour. This pragmatic study will focus on compatibility with existing infrastructure, while permitting a certain degree of adaptation to local needs and routines. Trial registration Nederlands Trial Register ISRCTN40008171

  14. FIELD TEST OF THE FLAME QUALITY INDICATOR

    Energy Technology Data Exchange (ETDEWEB)

    Rudin, Andrew M; Butcher, Thomas; Troost, Henry

    2003-02-04

    The flame quality indicator concept was developed at BNL specifically to monitor the brightness of the flame in a small oil burner and to provide a ''call for service'' notification when the brightness has changed from its setpoint, either high or low. In prior development work BNL has explored the response of this system to operational upsets such as excess air changes, fouled atomizer nozzles, poor fuel quality, etc. Insight Technologies, Inc. and Honeywell, Inc. have licensed this technology from the U.S. Department of Energy and have been cooperating to develop product offerings which meet industry needs with an optimal combination of function and price. Honeywell has recently completed the development of the Flame Quality Monitor (FQM or Honeywell QS7100F). This is a small module which connects via a serial cable to the burners primary operating control. Primary advantages of this approach are simplicity, cost, and ease of installation. Call-for-service conditions are output in the form of front panel indicator lights and contact closure which can trigger a range of external communication options. Under this project a field test was conducted of the FQM in cooperation with service organizations in Virginia, Pennsylvania, New Jersey, New York, and Connecticut. At total of 83 field sites were included. At each site the FQM was installed in parallel with another embodiment of this concept--the Insight AFQI. The AFQI incorporates a modem and provides the ability to provide detailed information on the trends in the flame quality over the course of the two year test period. The test site population was comprised of 79.5% boilers, 13.7% warm air furnaces, and 6.8% water heaters. Nearly all were of residential size--with firing rates ranging from 0.6 gallons of oil per hour to 1.25. During the course of the test program the monitoring equipment successfully identified problems including: plugged fuel lines, fouled nozzles, collapsed combustion

  15. Quality Assurance/Quality Control Jobs

    Science.gov (United States)

    Fanslau, Melody; Young, Janelle

    The production of a quality and safe food product is essential to the success of any food manufacturing facility. Because of this great importance, a career in quality can be extremely rewarding. Without happy customers willing to buy a product, a company would not be able to survive. Quality issues such as foreign objects, spoiled or mislabeled product, failure to meet net weight requirements, or a recall can all turn customers away from buying a product. The food industry is a customer-driven market in which some consumers are brand loyal based on a history of high quality or in which a single bad experience with a product will turn them away for a lifetime. With this said, the main role of a quality department is to help ensure that quality issues such as these are eliminated or kept to a minimum to maintain or increase the number of customers purchasing their product.

  16. The internal quality control and external quality assessment in application in microbiological test%室内质控和室间质评在微生物检验中的应用探讨

    Institute of Scientific and Technical Information of China (English)

    徐淼

    2015-01-01

    Objective:Clinical microbiological testing process,internal quality control and the role played by external quality assessG ment of effective analysis and evaluation,and further determine the clinical microbiological testing process problems.Methods:Selected clinical testing EQA 200 bacterial species as the main object of study,in accordance with the relevant standard analytical testing above 200 concurrent bacterial specimens,it further strains identified by related susceptibility testing is completed correctly identified strains above 200 strains complete identification.Strict complete identification results with a valid comparison and analysis of specimens in acG cordance with accreditation standards related to clinical specimens,identifying the reasons for those failures in depth.Results:All of the bacteria turn the above kinds of work are completed,188 identification is correct,the rest of the 12 identified error,the error is identiG fied six Gram-positive bacilli with six gram-negative bacilli.188 right above identified bacteria susceptibility testing following results obtained by the test results meet the 184 cases,the test results do not meet there are four bacteria,said the test results are not in line with the antibiotic penicillin.Conclusion:In effectively reduce laboratory errors in the process of identification of bacteria,clinical microG biology EQA plays a very important role,it is necessary to strictly internal quality control on the basis of clinical need for frequent miG crobiological testing and EQA work.%目的::对临床微生物检验过程中,室内质控以及室间质评所发挥的作用进行有效的分析评估,进一步确定临床微生物检验过程中出现的问题。方法:选取临床检验室间质评200株标本细菌作为主要的研究对象,依照相关的标准分析检验上述200株细菌标本,通过相关的药敏试验完成正确菌株的鉴定。严格按照相关的临床标本的鉴定标准完成鉴定结

  17. Determination and evaluation of air quality control. Manual of ambient air quality control in Germany

    Energy Technology Data Exchange (ETDEWEB)

    Lahmann, E.

    1997-07-01

    Measurement of air pollution emissions and ambient air quality are essential instruments for air quality control. By undertaking such measurements, pollutants are registered both at their place of origin and at the place where they may have an effect on people or the environment. Both types of measurement complement each other and are essential for the implementation of air quality legislation, particularly, in compliance with emission and ambient air quality limit values. Presented here are similar accounts of measurement principles and also contains as an Appendix a list of suitability-tested measuring devices which is based on information provided by the manufacturers. In addition, the guide of ambient air quality control contains further information on discontinuous measurement methods, on measurement planning and on the assessment of ambient air quality data. (orig./SR)

  18. Pre-examination Quality Control of Microbiological Testing Specimens%微生物检验标本分析前质量控制

    Institute of Scientific and Technical Information of China (English)

    谭敬秋

    2016-01-01

    Objective To explore the reasons for the failure of microbiological test specimens, development of clinical prac-tices microbiological testing quality control. Methods Recalling since 2014 in our hospital laboratory received 121 samples failed microbiological testing to calculate all kinds of unqualified specimen constituent ratio, mainly appear unqualified specimen analysis. Results 121 failed samples, sputum samples 55, accounting for 45.45%; 25 urine samples, accounting for 20.66%; 19 blood samples, accounting for 15.70%; secretion samples 12, accounting for 9.92%; seven stool specimens , accounting for 5.79%; sterile body fluid samples 3, accounting for 2.48%. Specimen contamination, acquisition time errors and untimely submission are the main reasons for the failure of the specimen. Conclusion Correct, standardized collection, specimens, storage, transport and processing specimen samples are premise on pre-examination quality control of microbio-logical testing specimens , the key is that inspectors should work closely with the medical staff, and effectively regulate the operation.%目的:探讨分析微生物检验标本不合格的原因,探讨微生物检验质量控制的临床操作规范。方法回顾2014年以来该院检验科收到的121份不合格微生物检验标本,计算各类不合格标本的构成比,分析不合格标本出现的主要原因。结果121份不合格标本中,痰液标本55份,占45.45%;尿液标本25份,占20.66%;血液标本19份,占15.70%;分泌物标本12份,占9.92%;粪便标本7份,占5.79%;无菌体液标本3份,占2.48%。标本污染、采集时间错误和送检不及时为不合格标本的主要原因。结论正确、规范的采集、留取、储存、运输和处理标本是微生物检验标本分析前质量控制的前提,关键在于检验人员应与医护人员密切配合,切实做到规范操作。

  19. Quantitative analysis of results of quality control tests in linear accelerators used in radiotherapy; Analise quantitativa dos resultados de testes de controle de qualidade em aceleradores lineares usados em radioterapia

    Energy Technology Data Exchange (ETDEWEB)

    Passaro, Bruno M.; Rodrigues, Laura N. [Instituto de Pesquisas Energeticas e Nucleares (IPEN/CNEN-SP), Sao Paulo, SP (Brazil); Videira, Heber S., E-mail: bruno.passaro@gmail.com [Universidade de Sao Paulo (HCFMRP/USP), Sao Paulo, SP (Brazil). Faculdade de Medicina. Hospital das Clinicas

    2013-04-15

    The aim of this study is to assess and analyze the stability of the calibration factor of three linear accelerators, as well as the other dosimetric parameters normally included in a program of quality control in radiotherapy. The average calibration factors of the accelerators for the period of approximately four years for the Clinac 600C and Clinac 6EX were (0.998±0.012) and (0.996±0.014), respectively. For the Clinac 2100CD 6 MV and 15 MV was (1.008±0.009) and (1.006±0.010), respectively, in a period of approximately four years. The data of the calibration factors were divided into four subgroups for a more detailed analysis of behavior over the years. Through statistical analysis of calibration factors, we found that for the 600C and Clinacs 2100CD, is an expected probability that more than 90% of cases the values are within acceptable ranges according to TG-142, while for the Clinac 6EX is expected around 85% since this had several exchanges of accelerator components. The values of TPR20,10 of three accelerators are practically constant and within acceptable limits according to the TG-142. It can be concluded that a detailed study of data from the calibration factor of the accelerators and TPR{sub 20},{sub 10} from a quantitative point of view, is extremely useful in a quality assurance program. (author)

  20. Home-based counseling and testing for HIV and syphilis - an evaluation of acceptability and quality control, in remote Amazonas State, Brazil.

    Science.gov (United States)

    Ribeiro, Luciana Viana da Costa; Sabidó, Meritxell; Galbán, Enrique; Guerra, Jorge Augusto de Oliveira; Mabey, David; Peeling, Rosanna W; Benzaken, Adele Schwartz

    2015-03-01

    Home-based, voluntary counselling and testing (HBCT) can help scale up early diagnosis. We aimed to evaluate the acceptance of HBCT for HIV and syphilis, estimate the prevalence among home-tested individuals and assess the performance of point-of-care testing by health staff using dried tube specimens (DTS) in a remote municipality of the Amazon region. Community health teams conducted door-to-door outreach in the urban area of São Gabriel da Cachoeira, Amazonas. HBCT for HIV and syphilis was offered to all residents aged ≥15 years. To provide an external quality assurance (EQA) of the healthcare workers' (HCW') ability to perform testing, DTS panels of reference samples were reconstituted and tested by the workers. HBCT was offered to 1752 individuals and accepted by 1501 (85.6%). Those tested had a median age 32.0 years, 64.4% were women and 85.1% were indigenous; none were previously tested using a rapid test. The prevalence of HIV was 0.37% in men and 0.0% in women; the prevalence of syphilis was 1.12% in men and 2.69% in women. Eleven HCW tested 44 DTS samples for HIV and 44 for syphilis. EQA testing revealed that workers interpreted 55.8% and 90.7% of HIV and syphilis reference samples correctly. HBCT was acceptable and successful in reaching untested individuals. However, there were concerns with the quality of test performance, highlighting the need for continual evaluation and retraining of community HCW. As Brazil scales up HIV and syphilis testing, our findings highlight how HBCT can maximise coverage in similar remote areas and improve knowledge about prevalence of these infections. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.

  1. Qualidade fisiológica de sementes de Eruca sativa L. pelo teste de deterioração controlada Physiological quality of Eruca sativa L. seeds by the test of controlled deterioration

    Directory of Open Access Journals (Sweden)

    Charline Zaratin Alves

    2011-12-01

    Full Text Available A qualidade da semente utilizada no processo de produção agrícola é um dos principais fatores a ser considerado para a implantação da cultura, havendo consenso entre todos os segmentos, sobre a importância do vigor das sementes e da necessidade de avaliá-lo. O presente trabalho teve o objetivo de estudar variações na condução do teste de deterioração controlada, verificando sua eficiência na identificação de diferentes níveis de vigor de sementes de rúcula, cultivar 'Cultivada' e 'Gigante' utilizando-se cinco lotes de sementes para cada um. As sementes foram submetidas à determinação do teor de água e a testes de germinação, primeira contagem de germinação, emergência e, para verificar a eficiência na identificação de diferentes níveis de vigor, foram estudadas variações no teste de deterioração controlada (teor de água de 18, 21 e 24%, a 45°C durante 24 e 48 horas. O experimento foi montado no delineamento inteiramente casualizado e os resultados foram submetidos à análise de variância, sendo que as médias foram comparadas pelo teste de Tukey a 5% de probabilidade. Pelos resultados obtidos no teste de deterioração controlada, observou-se que não houve relação com as avaliações iniciais do potencial fisiológico das sementes, principalmente para o teste de emergência. Concluiu-se que, nas condições estudadas, esse teste não é sensível o suficiente para a avaliação do potencial fisiológico de sementes de rúcula, para ambas as cultivares estudadas.The quality of the seed used in the process of agricultural production is one of the main factors to be considered for the implantation of the culture, having consensus between all the segments, on the importance of the vigor of the seeds and the necessity to evaluate it. This research had the purpose of studying proccedings for controlled deterioration test, to verify their sensitivity for identifying different vigor levels of arugula seed, cv

  2. Family Control and Earnings Quality

    Directory of Open Access Journals (Sweden)

    Carolina Bona Sánchez

    2007-06-01

    Full Text Available El trabajo analiza la relación entre el control familiar y la calidad de la información contable en un contexto en el que el tradicional conflicto de agencia entre directivos y accionistas se desplaza a la divergencia de intereses entre accionistas controladores y minoritarios. Los resultados alcanzados muestran que, en comparación con las no familiares, las empresas de naturaleza familiar divulgan unos resultados de mayor calidad, tanto en términos de menores ajustes por devengo discrecionales como de mayor capacidad de los componentes actuales del resultado para predecir los cash flows futuros. Además, el aumento en los derechos de voto en manos de la familia controladora incrementa la calidad de los resultados contables. La evidencia obtenida se muestra consistente con la presencia de un efecto reputación/vinculación a largo plazo asociado a la empresa familiar. Adicionalmente, el trabajo refleja que a medida que disminuye la divergencia entre los derechos de voto y de cash flow en manos de la familia controladora, aumenta la calidad de la información contable.PALABRAS CLAVE: derechos de voto, divergencia, empresa familiar, calidad delresultado, reputación, beneficios privados.This work examines the relationship between family control and earnings quality in a context where the salient agency problem shifts away from the classical divergence between managers and shareholders to conflicts between the controlling owner and minority shareholders. The results reveal that, compared to non-family firms, family firms reveal higher earnings quality in terms of both lower discretionary accruals and greater predictability of future cash flows. They also show a positive relationship between the level of voting rights held by the controlling family and earnings quality. The evidence is consistent with the presence of a reputation/long-term involvement effect associated with the family firm. Moreover, the work reflects that, as the divergence

  3. Is serological testing a reliable tool in laboratory diagnosis of syphilis? Meta-analysis of eight external quality control surveys performed by the german infection serology proficiency testing program.

    Science.gov (United States)

    Müller, Iris; Brade, Volker; Hagedorn, Hans-Jochen; Straube, Erich; Schörner, Christoph; Frosch, Matthias; Hlobil, Harald; Stanek, Gerold; Hunfeld, Klaus-Peter

    2006-04-01

    The accuracy of diagnostic tests is critical for successful control of epidemic outbreaks of syphilis. The reliability of syphilis serology in the nonspecialist laboratory has always been questioned, but actual data dealing with this issue are sparse. Here, the results of eight proficiency testing sentinel surveys for diagnostic laboratories in Germany between 2000 and 2003 were analyzed. Screening tests such as Treponema pallidum hemagglutination assay (mean accuracy, 91.4% [qualitative], 75.4% [quantitative]), Treponema pallidum particle agglutination assay (mean accuracy, 98.1% [qualitative], 82.9% [quantitative]), and enzyme-linked immunosorbent assays (ELISAs) (mean qualitative accuracy, 95%) were more reliable than Venereal Disease Research Laboratory (VDRL) testing (mean accuracy, 89.6% [qualitative], 71.1% [quantitative]), the fluorescent treponemal antibody absorption test (FTA-ABS) (mean accuracy, 88% [qualitative], 65.8% [quantitative]), and immunoblot assays (mean qualitative accuracy, 87.3%). Clearly, immunoglobulin M (IgM) tests were more difficult to manage than IgG tests. False-negative results for samples that have been unambiguously determined to be IgM and anti-lipoid antibody positive accounted for 4.7% of results in the IgM ELISA, 6.9% in the VDRL test, 18.5% in the IgM FTA-ABS, and 23.0% in the IgM immunoblot assay. For negative samples, the mean percentage of false-positive results was 4.1% in the VDRL test, 5.4% in the IgM ELISA, 0.7% in the IgM FTA-ABS, and 1.4% in the IgM immunoblot assay. On average, 18.3% of participants misclassified samples from patients with active syphilis as past infection without indicating the need for further treatment. Moreover, 10.2% of laboratories wrongly reported serological evidence for active infection in samples from patients with past syphilis or in sera from seronegative blood donors. Consequently, the continuous participation of laboratories in proficiency testing and further standardization of tests

  4. Quality control in breast tomosynthesis

    Energy Technology Data Exchange (ETDEWEB)

    Jakubiak, R.R.; Messias, P.C.; Santos, M.F., E-mail: requi@utfpr.edu.br [Universidade Tecnologia Federal do Parana (UTFPR), Curitiba, PR (Brazil). Departamento Academico de Fisica; Urban, L.A.B.D., E-mail: lineiurban@hotmail.com [Diagnostico Avancado por Imagem, Curitiba, PR (Brazil)

    2015-07-01

    In Brazil, breast cancer is the most common and the leading cause of death among women, with estimated 57,000 new cases in 2014. The mammography (2D) plays an important role in the early detection of breast cancer, but in some cases can be difficult to detect malignant lesions due overlap of breast tissues. The Digital Breasts Tomosynthesis (DBT: 3D) reduces the effects of overlap, providing improved characterization of mammographic findings. However, the dose may double as compared with mammography. This study presents results of Contrast to Noise Ratio (CNR) and image quality evaluation on Siemens mammography equipment Mammomat Inspiration with tomosynthesis. The CNR was determined with Polymethylmethacrylate (PMMA) layers of 20 to 70 mm thick and an aluminum foils of 0,2 mm thickness and area of 10 mm². Image quality was assessed with the ACR Breast Simulator. In the evaluation of image quality, the detectability of fibers and masses was identical in 2D and 3D systems. Displaying fibers were 4,5 and 4 mass in both modes. In 2D mode were identified 3,5 microcalcifications groups, and 3D showed 3 groups. The Mean Glandular Dose (MGD) for the simulator in 2D mode was 1,17 mGy and 2,35 mGy for the 3D mode. The result reinforces the importance of quality control in the process of obtaining the images and obtained in accordance CNR values, ensuring image quality and compatible dose in 2D and 3D processes. (author)

  5. Microbiological Quality Control of Probiotic Products

    OpenAIRE

    Astashkina, Anna Pavlovna; Khudyakova, L. I.; Kolbysheva, Yuliya Vladimirovna

    2014-01-01

    Microbiological quality control of probiotic products such as Imunele, Dannon, Pomogayka showed that they contain living cultures of the Lactobacillus Bifidobacterium genus in the amount of 107 CFU/ml, which corresponds to the number indicated on the label of products. It is identified that the survival rate of test-strains cultured with pasteurized products does not exceed 10%. The cell concentration of target-microorganisms was reduced by 20-45% after the interaction with living probiotic b...

  6. Quality control testing and evaluation for digital mammography%数字乳腺摄影系统的质量控制检测与评价

    Institute of Scientific and Technical Information of China (English)

    徐辉; 宛然; 郭丽; 王建超; 岳保荣

    2010-01-01

    目的 对3套数字乳腺摄影系统进行质量控制检测与评价.方法 应用欧洲乳腺癌普查和诊断质量控制导则中推荐的方法,结合国内乳腺摄影评价标准,对3套数字乳腺摄影系统进行X线发生器性能质量控制检测与评价;分别应用直接数字化X线摄影技术(DR)、相位对比乳腺摄影(PCM)和计算机X线摄影技术(CR)系统在4个厚度下(30、40、50及60 mm)对乳腺专用对比度细节检测模体(CDMAM 3.4)进行AEC曝光成像,计算与评价每一厚度下的平均腺体剂量(AGD)和影像质量因子(IQF).结果 DR和CR的x线机性能检测符合现有标准;等效PMMA厚度分别为30、40、50、60 mm时,DR系统的AGD分别为1.20、1.42、1.75、2.20 mGy;PCM系统AGD分别是0.82、1.19、1.33、1.70 mGy;CR系统AGD为0.59、0.88、1.47、2.19 mGy.在相应的模体厚度下,DR系统的IQF值为21.36、21.57、27.25和30.58;PCM和CR系统的IQF值分别为28.02、29.10、35.90、41.24和39.78、39.30、43.85、48.08.结论 GBZ 186-2007标准不适用于PCM系统X线机性能部分性能的评价.本研究的3套系统自动曝光下平均腺体剂量均符合欧洲标准.在国内检测规范欠缺的情况下,可参考国际标准或指南对数字乳腺系统进行常规监测.%Objective To carry out the quality control testing and evaluation for three digital mammography systems.Methods The performance of three digital mammography systems was assessed by applying methods recommended in the European guidelines for quality assurance in breast cancer screening and diagnosis and Chinese specification for testing of quality control in X-ray mammography.The performance of X-ray generator of three digital mammography systems were tested and evaluated.CDMAM 3.4 phantom with four different thickness(30,40,50,60 mm) were exposured in DR,PCM,and CR system,respectively.The average glandular dose (AGD) value was measured and image quality figure (IQF) analysis was performed in each thickness

  7. Concrete and steel construction quality control and assurance

    CERN Document Server

    El-Reedy, Mohamed A

    2014-01-01

    Starting with the receipt of materials and continuing all the way through to the final completion of the construction phase, Concrete and Steel Construction: Quality Control and Assurance examines all the quality control and assurance methods involving reinforced concrete and steel structures. This book explores the proper ways to achieve high-quality construction projects, and also provides a strong theoretical and practical background. It introduces information on quality techniques and quality management, and covers the principles of quality control. The book presents all of the quality control and assurance protocols and non-destructive test methods necessary for concrete and steel construction projects, including steel materials, welding and mixing, and testing. It covers welding terminology and procedures, and discusses welding standards and procedures during the fabrication process, as well as the welding codes. It also considers the total quality management system based on ISO 9001, and utilizes numer...

  8. Test and inspection for process control of monolithic circuits

    Science.gov (United States)

    Spangenberg, E.

    1967-01-01

    Report details the test and inspection procedures for the mass production of high reliability integrated circuits. It covers configuration control, basic fundamentals of quality control, control charts, wafer process evaluation, general process evaluation, evaluation score system, and diffusion evaluation.

  9. Computerized triaxial test control methods

    DEFF Research Database (Denmark)

    Sabaliauskas, Tomas; Ibsen, Lars Bo

    2016-01-01

    capabilities of the setup are extended by using a programmable hydraulic piston with real time feedback loops. The control methods provided by the controller mimic those applied in computer simulations. Force control, displacement control or a combination of both can be used. Single diameter height sample...... control methods provide access to testing both direct and inverse stiffness matrix response as well as to observe strain creep and stress relaxation directly....

  10. High definition viral vaccine strain identity and stability testing using full-genome population data--The next generation of vaccine quality control.

    Science.gov (United States)

    Höper, Dirk; Freuling, Conrad M; Müller, Thomas; Hanke, Dennis; von Messling, Veronika; Duchow, Karin; Beer, Martin; Mettenleiter, Thomas C

    2015-10-26

    Vaccines are the most effective prophylactic public health tools. With the help of vaccines, prevention of infectious disease spread and, in concert with other measures, even eradication has become possible. Until now, licensing and quality control require the determination of consensus genome sequences of replication competent infectious agents contained in vaccines. Recent improvements in sequencing technologies now enable the sequencing of complete genomes and the genetic analysis of populations with high reliability and resolution. The latter is particularly important for RNA viruses, which consist of fluctuating heterogeneous populations rather than genetically stable entities. This information now has to be integrated into the existing regulatory framework, challenging both licensing authorities and vaccine producers to develop new quality control criteria. Commercially available modified-live oral rabies vaccines and their precursor strains were deep-sequenced to assess strain identity and relations between strains based on population diversity. Strain relations were inferred based on the Manhattan distances calculated between the compositions of the viral populations of the strains. We provide a novel approach to assess viral strain relations with high resolution and reliability by deep sequencing with subsequent analysis of the overall genetic diversity within the viral populations. A comparison of our novel approach of inferring strain relations based on population data with consensus sequence analysis clearly shows that consensus sequence analysis of diverse viral populations can be misleading. Therefore, for quality control of viral vaccines deep sequencing analysis is to be preferred over consensus sequence analysis. The presented methodology allows for routine integration of deep sequencing data in vaccine quality control and licensing for highly reliable assessment of strain identity and stability. Copyright © 2015 Elsevier Ltd. All rights reserved.

  11. Internal quality control: best practice.

    Science.gov (United States)

    Kinns, Helen; Pitkin, Sarah; Housley, David; Freedman, Danielle B

    2013-12-01

    There is a wide variation in laboratory practice with regard to implementation and review of internal quality control (IQC). A poor approach can lead to a spectrum of scenarios from validation of incorrect patient results to over investigation of falsely rejected analytical runs. This article will provide a practical approach for the routine clinical biochemistry laboratory to introduce an efficient quality control system that will optimise error detection and reduce the rate of false rejection. Each stage of the IQC system is considered, from selection of IQC material to selection of IQC rules, and finally the appropriate action to follow when a rejection signal has been obtained. The main objective of IQC is to ensure day-to-day consistency of an analytical process and thus help to determine whether patient results are reliable enough to be released. The required quality and assay performance varies between analytes as does the definition of a clinically significant error. Unfortunately many laboratories currently decide what is clinically significant at the troubleshooting stage. Assay-specific IQC systems will reduce the number of inappropriate sample-run rejections compared with the blanket use of one IQC rule. In practice, only three or four different IQC rules are required for the whole of the routine biochemistry repertoire as assays are assigned into groups based on performance. The tools to categorise performance and assign IQC rules based on that performance are presented. Although significant investment of time and education is required prior to implementation, laboratories have shown that such systems achieve considerable reductions in cost and labour.

  12. Spaceport Command and Control System Automation Testing

    Science.gov (United States)

    Hwang, Andrew

    2017-01-01

    The Spaceport Command and Control System (SCCS) is the National Aeronautics and Space Administrations (NASA) launch control system for the Orion capsule and Space Launch System, the next generation manned rocket currently in development. This large system requires high quality testing that will properly measure the capabilities of the system. Automating the test procedures would save the project time and money. Therefore, the Electrical Engineering Division at Kennedy Space Center (KSC) has recruited interns for the past two years to work alongside full-time engineers to develop these automated tests, as well as innovate upon the current automation process.

  13. Spaceport Command and Control System Automated Testing

    Science.gov (United States)

    Stein, Meriel

    2017-01-01

    The Spaceport Command and Control System (SCCS) is the National Aeronautics and Space Administrations (NASA) launch control system for the Orion capsule and Space Launch System, the next generation manned rocket currently in development. This large system requires high quality testing that will properly measure the capabilities of the system. Automating the test procedures would save the project time and money. Therefore, the Electrical Engineering Division at Kennedy Space Center (KSC) has recruited interns for the past two years to work alongside full-time engineers to develop these automated tests, as well as innovate upon the current automation process.

  14. Development of an in vitro antigen-detection test as an alternative method to the in vivo plaque reduction neutralization test for the quality control of Japanese encephalitis virus vaccine.

    Science.gov (United States)

    Kim, Do Keun; Kim, Hye-Youn; Kim, Joo-Young; Ye, Michael B; Park, Kee-Bum; Han, Euiri; Kim, Jaeok; Ja Ban, Sang; Hong, Seung Hwa; Park, Yong Keun; Nam, Jae-Hwan

    2012-07-01

    Japanese encephalitis virus (JEV) causes diseases that attack the human central nervous system. Traditionally, the quality control for JEV vaccines, in which the plaque reduction neutralization (PRN) titer is measured by the national control laboratories before the vaccine batches are marketed, has required laboratory animal testing. However, classical animal tests have inherent problems, including the very fact that animals are used, ethical issues, and the possibility of error. In this study, JEV antigen was measured in an in vitro assay to assess the feasibility of replacing in vivo assays that measure the PRN titers of JEV vaccines. We constructed a double-sandwich enzyme-linked immunosorbent assay (DS-ELISA) that could detect JEV envelope (E). Initially, monoclonal antibodies (mAbs) directed against the JEV E protein were generated and characterized. We isolated 18 mAbs against JEV E protein, and most were the IgG1 or IgG2a isotype. The mAbs (5F15 and 7D71) were selected as the most suitable mAb pair to detect JEV E protein. DS-ELISA with this pair detected as little as approximately 3 μg/mL JEV E protein and demonstrated a relationship between the amount of JEV E protein and the PRN titer. From these results, we surmise that this DS-ELISA may be useful, not only in terms of measuring the amount of JEV E protein, but also as a substitute for the PRN test for JEV vaccine evaluation.

  15. AUTOMATION OF THE SYSTEM OF INTERNAL LABORATORY QUALITY CONTROL

    Directory of Open Access Journals (Sweden)

    V. Z. Stetsyuk

    2015-05-01

    Full Text Available Quality control system base d on the principles of standardi zation of all phases of laboratory testing and analysis of internal laboratory quality control and external quality assessment. For the detection accuracy of the results of laboratory tests, carried out internally between the laboratory and laboratory quality control. Under internal laboratory quality control we understand measurement results of each analysis in each anal ytical series rendered directly in the lab every day. The purpose of internal laboratory control - identifying and eliminating unacceptable deviations from standard perfor mance test in the laboratory, i.e. identifying and eliminating harmful analytical errors. The solutions to these problems by implementing automated systems - software that allows you to optimize analytical laboratory research stage of the procedure by automatically creating process control charts was shown.

  16. [Quality control in microbiology (author's transl)].

    Science.gov (United States)

    Lamanna, A

    1977-01-01

    The microbiology quality control importance is emphasized and some particular problems that quality control presents in microbiology are also indicated. There are two types of microbiology quality control as well as for hematology and chemical chemistry: collective quality control, between more laboratories, and individual quality control, in the sphere of each laboratory. A.M.O.I. (Associazione Microbiologi Ospedalieri Italiani) and I.S.V.T. (Istituto Sieroterapico Vaccinogeno Toscano) Sclavo collaborating, have organized a collective quality control between laboratories of different hospitals during the year 1974 and 1975. The results of this control are reported. Although preliminary, they indicate practical importance of microbiology control. During 1975, in fact, the pathogens isolated have been in high percentage than 1976. At last, the future quality control's program aiming at methods's standardization and technical, methodical instructions is indicated.

  17. 33 CFR 385.21 - Quality control.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 3 2010-07-01 2010-07-01 false Quality control. 385.21 Section... Processes § 385.21 Quality control. (a) The Corps of Engineers and the non-Federal sponsor shall prepare a quality control plan, in accordance with applicable Corps of Engineers regulations, for each product...

  18. 7 CFR 930.44 - Quality control.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 8 2010-01-01 2010-01-01 false Quality control. 930.44 Section 930.44 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements... Control § 930.44 Quality control. (a) Quality standards. The Board may establish, with the approval of...

  19. 7 CFR 981.42 - Quality control.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 8 2010-01-01 2010-01-01 false Quality control. 981.42 Section 981.42 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements... Regulating Handling Quality Control § 981.42 Quality control. (a) Incoming. Except as provided in...

  20. 14 CFR 21.139 - Quality control.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Quality control. 21.139 Section 21.139... PROCEDURES FOR PRODUCTS AND PARTS Production Certificates § 21.139 Quality control. The applicant must show that he has established and can maintain a quality control system for any product, for which...

  1. 统计质量保证技术在分析测试实验室内部质量控制中的应用%Application of SQA Techniques to Analytical and Testing Laboratories for Internal Quality Control

    Institute of Scientific and Technical Information of China (English)

    王斗文; 万秉忠

    2001-01-01

    对通过统计质量保证( SQA)技术进行分析测试实验室内部质量控制( IQC)的方法作了初探。研究结果表明,SQA技术的应用能保证实验室始终处于统计受控状态,确保测试数据的有效性,有利于分析测试实验室质量保证活动的开展。%In this paper,a method of internal quality control for analytical and testing laboratories by statistical quality assurance(SQA) techniques is discussed.Application of SQA techniques can be continuously ensure that analytical and testing data of the laboratories are in statistical _ control state,thus guaranteeing the data quality and indicating areas of potential improvement for the laboratories.

  2. Quality Control of EUVE Databases

    Science.gov (United States)

    John, Linda M.

    1993-01-01

    The publicly accessible databases for the Extreme Ultraviolet Explorer (EUVE) include: the EUVE Archive Mailserver, the Center for EUV Astrophysics ftp site, the EUVE Guest Observer Mailserver, and the Astronomical Data System node. The EUVE Performance Assurance team is responsible for verifying that these public databases are working properly and that the public availability of EUVE data contained therein does not infringe any data rights which may have been assigned. In this paper, we describe the quality assurance (QA) procedures we have developed from approaching QA as a service organization; this approach reflects the overall EUVE philosophy of QA integrated into normal operating procedures, rather than imposed as an external, post-facto, control mechanism.

  3. Flying spin qualities testing of airplane

    Directory of Open Access Journals (Sweden)

    Kostić Čedomir J.

    2015-01-01

    Full Text Available In this paper is presented the theoretical analysis of origins and characteristics of spinning motion. There are precise explanation of every stage spin flight and basic meaning of notion. Personated equation of motion in spin and equitation of motion airplane in settled spin motion, analysis of them and general recommendation for pilots for recovering from spins. Introduced in valid military and civil specifications flight test demonstration requirements for departure resistance and flying stall and spin qualities testing of airplane. Special attention was given on predicting departure, stall and spin susceptibility and theoretical analysis in the name of magnify flight testing security. There are explanation of test equipment and methodology of flying qualities testing of airplanes. Like a support of this theme are described method and results of flight stall and spin qualities testing of airplane G-4(N-62 super see-gull with precise recommendation for pilots for recovering from spins, from TOC SLI VS (Technical testing center, department for fight testing Air Force of Serbia.

  4. Forward SCT Module Assembly and Quality Control at IFIC Valencia

    CERN Document Server

    Mitsou, V A; Civera, J V; Costa, M J; Escobar, C; Fuster, J; García, C; García-Navarro, J E; González, F; González-Sevilla, S; Lacasta, C; Llosá, G; Martí i García, S; Miñano, M; Modesto, P; Nácher, J; Rodríguez-Oliete, R; Sánchez, F J; Sospedra, L; Strachko, V

    2007-01-01

    This note discusses the assembly and the quality control tests of 282 forward detector modules for the ATLAS Semiconductor Tracker assembled at the Instituto de Fisica Corpuscular (IFIC) in Valencia. The construction and testing procedures are outlined and the laboratory equipment is briefly described. Emphasis is given on the module quality achieved in terms of mechanical and electrical stability.

  5. Spinal cord testing: auditing for quality assurance.

    Science.gov (United States)

    Marr, J A; Reid, B

    1991-04-01

    A quality assurance audit of spinal cord testing as documented by staff nurses was carried out. Twenty-five patient records were examined for accuracy of documented testing and compared to assessments performed by three investigators. A pilot study established interrater reliability of a tool that was designed especially for this study. Results indicated staff nurses failed to meet pre-established 100% standard in all categories of testing when compared with investigator's findings. Possible reasons for this disparity are discussed as well as indications for modifications in the spinal testing record, teaching program and preset standards.

  6. Quality control for laboratory diagnosis for hand, foot and mouth ...

    African Journals Online (AJOL)

    McRoy

    management is supportive and symptomatic ... concern. Key words: Hand, foot and mouth disease, viral, quality, control. ... viral testing as a tool for fighting the HFMD. However ... [7]. Indeed, the more advanced tests such as immunological tests is also available at present.[8- ... new gold standard virological test based on the.

  7. Testing Karasek's Demands-Control Model in restructured healthcare settings: effects of job strain on staff nurses' quality of work life.

    Science.gov (United States)

    Laschinger, H K; Finegan, J; Shamian, J; Almost, J

    2001-05-01

    Job strain among staff nurses has become an increasingly important concern in relationship to employee performance and commitment to the organization in current restructured healthcare settings. The purpose of this study was to test Karasek's Demands-Control Model of job strain by examining the extent to which the degree of job strain in nursing work environments affects staff nurses' perceptions of structural and psychological empowerment, work satisfaction, and organizational commitment. A predictive, nonexperimental design was used to test these relationships in a random sample of 404 Canadian staff nurses. Karasek's Job Content Questionnaire, the Conditions of Work Effectiveness Questionnaire-II, Spreitzer's Psychological Empowerment Questionnaire, Meyer and Allen's Organizational Commitment Questionnaire, and the Global Satisfaction Scale were used to measure the major study variables. Nurses with higher level of job strain were found to be significantly more empowered, more committed to the organization, and more satisfied with their work. Support for Karasek's Demands/Control theory was established in this study.

  8. Quality control parameters for Tamra (copper) Bhasma.

    Science.gov (United States)

    Jagtap, Chandrashekhar Yuvaraj; Prajapati, Pradeepkumar; Patgiri, Biswajyoti; Shukla, Vinay J

    2012-04-01

    Metallic Bhasmas are highly valued and have their own importance in Ayurvedic formulations. To testify the Bhasmas various parameters have been told in Rasashastra classics. Tamra Bhasma (TB) with its different properties is used in the treatment of various diseases is quiet famous among the Ayurvedic physicians (Vaidyas). The present study was carried out to set up the quality control parameters for the TB by making the use of classical tests along with advanced analytical tools. Copper wire taken for the preparation of Bhasma was first analyzed for its copper content and then subjected to Shodhana, Marana and Amrutikarana procedures as per the classical references. Final product complied with all the classical parameters like Rekhapurnatwa, Varitaratwa etc. After complying with these tests TB was analyzed by advanced analytical techniques like particle size distribution (PSD) analysis, scanning electron microscopy (SEM), and inductive coupled plasma spectrometry (ICP). PSD analysis of TB showed volumetric mean diameter of 28.70 μm, 50% of the material was below 18.40 μm size. Particle size less than 2μm were seen in SEM. 56.24 wt % of copper and 23.06 wt % of sulphur was found in ICP-AES. Heavy metals like cadmium, selenium were not detected while others like arsenic, lead and mercury were present in traces. These observations could be specified as the quality control parameters conforming to all the classical tests under the Bhasma Pariksha.

  9. Iowa Central Quality Fuel Testing Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Heach, Don; Bidieman, Julaine

    2013-09-30

    The objective of this project is to finalize the creation of an independent quality fuel testing laboratory on the campus of Iowa Central Community College in Fort Dodge, Iowa that shall provide the exploding biofuels industry a timely and cost-effective centrally located laboratory to complete all state and federal fuel and related tests that are required. The recipient shall work with various state regulatory agencies, biofuel companies and state and national industry associations to ensure that training and testing needs of their members and American consumers are met. The recipient shall work with the Iowa Department of Ag and Land Stewardship on the development of an Iowa Biofuel Quality Standard along with the Development of a standard that can be used throughout industry.

  10. Information Quality Control of ERP System

    Institute of Scientific and Technical Information of China (English)

    2002-01-01

    From the viewpoint of manufacturing enterprises, th is thesis discusses the concept and definition of information quality as well as t he connotation of information quality. Based on our personal experiences of many years, we have summarized the cases of success and failure with ERP system, an d from the angle of information quality control, we have come up with the follow ing concepts : static information quality of enterprises, information maturity o f enterprises and dynamic information quality.Inform...

  11. Psychometric issues and test quality in the Netherlands

    NARCIS (Netherlands)

    Egberink, Iris; Hurks, Petra

    2016-01-01

    The Dutch Committee on Tests and Testing (COTAN) aims at improving test use and test quality in the Netherlands. Improving test use is done by raising standards in the use of psychological tests. Improving test quality is done by assessing the quality of different psychological instruments that are

  12. Psychometric issues and test quality in the Netherlands

    NARCIS (Netherlands)

    Egberink, I.J.L.; Hurks, P.P.M.

    The Dutch Committee on Tests and Testing (COTAN) aims at improving test use and test quality in the Netherlands. Improving test use is done by raising standards in the use of psychological tests. Improving test quality is done by assessing the quality of different psychological instruments that are

  13. 食品、药品微生物检测实验室质量控制方法分析%Analysis of laboratory quality control methods for microbiological testing of food and medicine

    Institute of Scientific and Technical Information of China (English)

    刘锐萍; 王峰; 刘珊珊; 杜伟; 赵广西

    2013-01-01

    Systematic analysis of the laboratory quality control methods for microbiological testing of food and medicine was performed,including analysis on the overall control of environment condition,the management of sterile room,sample management,equipment management,personnel management,medium quality control,standard bacterial (toxic) strain management,process control,and record maintein,aiming at providing systematic guidance for the quality control of microbiological laboratory work,and improving the accuracy of the microbial tests.%系统分析食品、药品微生物检测实验室的质量控制方法,从总体环境条件控制、微生物室管理、样品管理、仪器设备管理、人员管理、培养基质量控制、标准菌(毒)种管理、操作过程控制、记录管理等9个方面进行系统分析,对微生物实验室的质量控制工作提供系统指导,提高微生物检测结果的准确性.

  14. 粘土湿型砂处理系统的在线检测及质量控制%On-Line Test and Quality Control of Green Clay Moulding Sand Treating System

    Institute of Scientific and Technical Information of China (English)

    吴毅

    2011-01-01

    简述了型砂在线检测装置与质量控制系统的发展过程,介绍了以日本新东公司的MIA、MIC、MIE型砂控制系统为典型代表的全程在线检测装置与质量控制系统、以德国爱立许公司的质量师系统为典型代表的全程在线检测装置与质量控制系统和以常州好迪公司为代表的国产SC在线检测及质量控制装置的特点、控制精度及适用范围,总结了在线检测装置与质量控制系统的选用原则及注意事项.%The development process of the on-line test device and the quality control system was briefly described. An introduction was given to the characteristics and their application scope of some typical on-line full process test devices and the quality control systems including the SINTO-MIA, MIC, MIE moulding sand control system (Japan), EIRICH quality master system (Germany), and as well as, the on-line test and control device developed by the Haodi company(Changzhou, China) through assimilating the advanced technique from abroad. The usage principle and matters to be pay attentions of the on-line test device and quality system was also proposed.

  15. Shipping/Receiving and Quality Control

    Data.gov (United States)

    Federal Laboratory Consortium — Shipping receiving, quality control, large and precise inspection and CMM machines. Coordinate Measuring Machines, including "scanning" probes, optical comparators,...

  16. MAIN PROBLEMS OF CONTROLLING OF THE QUALITY

    Directory of Open Access Journals (Sweden)

    Orlov A. I.

    2015-09-01

    Full Text Available Controlling of statistical methods to ensure product quality is the special case of controlling organizational and economic methods of management. Today, controlling in the practice of management of Russian companies is understood as "the system of information-analytical and methodological support to achieve their goals." The controller is developing a decision-making rules, the head takes decisions on the basis of these rules. We proved the concept of "controlling of methods". Innovation in management is based, in particular, on the use of new adequate organizational-economic (as well as economicmathematical and statistical methods. Controlling in this area - is the development and application procedures of compliance management used and newly developed (implemented organizationaleconomic methods for the task. Thus, the methodology for controlling is of great practical value in any field in which the actions (operations must be carried out in accordance with certain rules (regulations, standards, guidelines, as in any such area in which we need to use development and application procedures of compliance management used and the newly established (implemented rules for solution of tasks assigned to the organization. In this article, we select a area of controlling as controlling quality, and we discuss its main issues. This is about controlling of organizational-economic methods to ensure product quality, especially about the statistical methods based on probability theory and mathematical statistics. We consider the analysis and synthesis of plans of statistical quality control, optimization options plans of statistical control, truncated plans. Are discussed the differences control plans provider and the consumer, the allocation of units formless (liquid, gas products, the selection of a random sample of the statistical quality control of products, lower estimate of the required sample size. It is established, that is not always necessary

  17. 40 CFR Appendix A to Subpart S of... - Calibrations, Adjustments and Quality Control

    Science.gov (United States)

    2010-07-01

    ...—Calibrations, Adjustments and Quality Control (I) Steady-State Test Equipment States may opt to use transient emission test equipment for steady-state tests and follow the quality control requirements in paragraph (II... better quality control using different frequencies. Gas calibration shall be accomplished by...

  18. Descriptive study of the quality control in mammography; Estudio descriptivo del control de calidad en mamografia

    Energy Technology Data Exchange (ETDEWEB)

    Gaona, E.; Perdigon C, G.M.; Casian C, G.A.; Azorin N, J.; Diaz G, J.A.I.; Arreola, M. [UAM, Xochimilco 14000 Mexico D.F. (Mexico)

    2005-07-01

    The goal of mammography is to provide contrast between a lesion that is possible residing within the breast and normal surrounding tissue. Quality control is essential for maintaining the contrast imaging performance of a mammography system and incorporate tests that are relevant in that they are predictive of future degradation of contrast imaging performance. These tests will also be done at frequency that is high enough to intercept most drifts in quality imaging or performance before they become diagnostically significant. The quality control study has as objective to describe the results of the assessment of quality imaging elements (film optical density, contrast (density difference), uniformity, resolution and noise) of 62 mammography departments without quality control program and comparison these results with a mammography reference department with a quality control program. When comparing the results they allow seeing the clinical utility of to have a quality control program to reduce the errors of mammography interpretation. (Author)

  19. Testing and Problem Analysis of Quality Control of Micro-injection Pump%微量注射泵的质量控制检测及问题分析

    Institute of Scientific and Technical Information of China (English)

    王梦婷; 徐林

    2014-01-01

    微量注射泵所用药物及剂量比较特殊,为了保证医患的人身安全以及设备的治疗质量,我院对微量注射泵进行了质量控制检测工作,同时对检测结果及检测过程中出现的问题进行分析,找出了解决问题的方法及对策,为更好地开展质量控制工作提供参考。%According to the particularity of drugs with their dosages used in micro-injection pumps, quality control testing of micro-injection pumps was conducted as well as the testing results and problems exist in the testing process were analyzed in the hospital, in order to ensure the personal safety of doctors and patients as well as the treatment quality of micro-injection pumps. The methods and countermeasures of solving relevant problems which can provide reference information for quality control testing of micro-injection pumps were also discussed in this paper.

  20. IMPROVEMENT OF THE QUALITY CONTROL OF ELISA TESTING FOR THE LABORATORY CONFIRMATION OF MEASLES AND RUBELLA INFECTIONS AT THE STAGE OF THE MEASLES/ RUBELLA ELIMINATION PROGRAM

    Directory of Open Access Journals (Sweden)

    T. A. Mamaeva

    2017-01-01

    .u. (р < 0.05 in EcoLab and Siemens ELISA test-systems correspondently. In the studies when the ILC working solution parameters for ELISA of “capture” and “indirect” formats were evaluated the statistic reliability and high information capability of the mathematic models of the OD value changes vs. the degree of dilution of the initial ILC were determined. For the “capture” and “indirect” formats the determination coefficient (R2 consisted 97.34 and 99.29 correspondently, the Fisher criteria (F — 219.62 and 556.55 correspondently, the significance level (p — < 0.05 for both formats. The evaluated optimal working dilution degrees of the IgM-containing ILC make possible to exclude the influence of the IgG antibodies as the non-target marker in the ILC. On the other hand, taking into account the format of the used ELISA kit the optimal working dilution degrees give the possibility to obtain the desirable 2–3 “cut-off” values of the specific marker. Moreover, the issue of the target marker quantitative content in ILC is discussed in the study. In order to improve the quality of the commercial MRV IgM and IgG ELISA test-systems the joint studies with those who develop and produce these systems are desirable to be organized.

  1. Establishment for quality control of experimental animal

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Tae Hwan; Kim, Soo Kwan; Kim, Tae Kyoung

    1999-06-01

    Until now, because we have imported experimental animal from foreign experimental animal corporation, we could have saved money by establishing the quality control of animal in barrier system. In order to improve the quality of animal experiment and efficiency of biomedical study, it is indispensable to control many factors that effect in the experiment. Therefore, it is essential to organize the system of laboratory animal care for enhancing reliability and revivability of experimental results. The purpose of the present investigation was to establish the quality control system of experimental animals that we can provide good quality animals according to the experimental condition of each investigator although the exact quality control system to estimate the infection of bacteria and virus easily remains ill-defined yet. Accordingly, we established the useful quality control system for microbiologic monitoring and environmental monitoring to protect experimental animal from harmful bacteria and virus.

  2. Colorado Air Quality Control Regulations and Ambient Air Quality Standards.

    Science.gov (United States)

    Colorado State Dept. of Health, Denver. Div. of Air Pollution Control.

    Regulations and standards relative to air quality control in Colorado are defined in this publication. Presented first are definitions of terms, a statement of intent, and general provisions applicable to all emission control regulations adopted by the Colorado Air Pollution Control Commission. Following this, three regulations are enumerated: (1)…

  3. 21 CFR 866.5910 - Quality control material for cystic fibrosis nucleic acid assays.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Quality control material for cystic fibrosis... Test Systems § 866.5910 Quality control material for cystic fibrosis nucleic acid assays. (a) Identification. Quality control material for cystic fibrosis nucleic acid assays. A quality control material...

  4. Quality Control in Production Processes

    Directory of Open Access Journals (Sweden)

    Prístavka Miroslav

    2016-09-01

    Full Text Available The tools for quality management are used for quality improvement throughout the whole Europe and developed countries. Simple statistics are considered one of the most basic methods. The goal was to apply the simple statistical methods to practice and to solve problems by using them. Selected methods are used for processing the list of internal discrepancies within the organization, and for identification of the root cause of the problem and its appropriate solution. Seven basic quality tools are simple graphical tools, but very effective in solving problems related to quality. They are called essential because they are suitable for people with at least basic knowledge in statistics; therefore, they can be used to solve the vast majority of problems.

  5. Quality control education in the community college

    Science.gov (United States)

    Greene, J. Griffen; Wilson, Steve

    1966-01-01

    This paper describes the Quality Control Program at Daytona Beach Junior College, including course descriptions. The program in quality control required communication between the college and the American Society for Quality Control (ASQC). The college has machinery established for certification of the learning process, and the society has the source of teachers who are competent in the technical field and who are the employers of the educational products. The associate degree for quality control does not have a fixed program, which can serve all needs, any more than all engineering degrees have identical programs. The main ideas which would be common to all quality control programs are the concept of economic control of a repetitive process and the concept of developing individual potentialities into individuals who are needed and productive.

  6. Handling qualities requirements for control configured vehicles

    Science.gov (United States)

    Woodcock, R. J.; George, F. L.

    1976-01-01

    The potential effects of fly by wire and control configured vehicle concepts on flying qualities are considered. Failure mode probabilities and consequences, controllability, and dynamics of highly augmented aircraft are among the factors discussed in terms of design criteria.

  7. Employee quality, monitoring environment and internal control

    Directory of Open Access Journals (Sweden)

    Chunli Liu

    2017-03-01

    Full Text Available We investigate the effect of internal control employees (ICEs on internal control quality. Using special survey data from Chinese listed firms, we find that ICE quality has a significant positive influence on internal control quality. We examine the effect of monitoring on this result and find that the effect is more pronounced for firms with strict monitoring environments, especially when the firms implement the Chinese internal control regulation system (CSOX, have higher institutional ownership or attach greater importance to internal control. Our findings suggest that ICEs play an important role in the design and implementation of internal control systems. Our study should be of interest to both top managers who wish to improve corporate internal control quality and regulators who wish to understand the mechanisms of internal control monitoring.

  8. 7 CFR 981.442 - Quality control.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 8 2010-01-01 2010-01-01 false Quality control. 981.442 Section 981.442 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements... Administrative Rules and Regulations § 981.442 Quality control. (a) Incoming. Pursuant to § 981.42(a),...

  9. 30 CFR 74.6 - Quality control.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Quality control. 74.6 Section 74.6 Mineral... of the CMDPSU will be maintained in production through adequate quality control procedures, MSHA and... DUST SAMPLING DEVICES Approval Requirements for Coal Mine Dust Personal Sampler Unit § 74.6...

  10. Control of image quality in mammography. Influence of assessing subjective image of a test object; Control de calidad de imagen en mamografia. Influencia de la valoracion subjetiva de la imagen de un objeto de prueba

    Energy Technology Data Exchange (ETDEWEB)

    Hernandez Concepcion, E.; Garrido Breton, C.; Batista Arce, A.; Gonzalez Lopez, S.; Catalan Acosta, A.; Hernandez Armas, J.

    2013-07-01

    . The object of this work is to assess the influence of the observer in the control of image quality to the digital mammography machine of our hospital, establishing reference values and tolerances that take into account the variability between observers. (Author)

  11. The test of intrinsic uniformity is one of the basic tests to check the status of the detectors of gamma cameras, and as such is contained in RD 1 841/1997 Quality Control in Nuclear Medicine; Protocolo NEMA para el calculo de la uniformidad intrinsica en gamma-camaras: aplicacion y comparacion con el software del fabricante

    Energy Technology Data Exchange (ETDEWEB)

    Gonzalez Soto, X. L.; Gonzalez Ruiz, C.; Lopez-Boto, M. A.; Polo Cezon, R.

    2015-07-01

    Spanish Protocol Quality Control Instrumentation in Nuclear Medicine provides guidelines for conducting this test, similar to those established in the NEMA protocol NEMA Protocol for the calculation of the uniformity intrinsic in GAMMA cameras: application and comparison with the SQFTWARE of the manufacturer. it is advisable to conduct a study to ensure that the results for the test of intrinsic uniformity of the software provided by the equipment manufacturer are equivalent to those obtained by applying the protocol recommended by the SEFM before using this software for performing quality control. (Author)

  12. Sensometrics for Food Quality Control

    DEFF Research Database (Denmark)

    Brockhoff, Per B.

    2011-01-01

    The industrial development of innovative and succesful food items and the measuring of food quality in general is difficult without actually letting human beings evaluate the products using their senses at some point in the process. The use of humans as measurement instruments calls for special...

  13. Chronic Low Quality Sleep Impairs Postural Control in Healthy Adults.

    Science.gov (United States)

    Furtado, Fabianne; Gonçalves, Bruno da Silva B; Abranches, Isabela Lopes Laguardia; Abrantes, Ana Flávia; Forner-Cordero, Arturo

    2016-01-01

    The lack of sleep, both in quality and quantity, is an increasing problem in modern society, often related to workload and stress. A number of studies have addressed the effects of acute (total) sleep deprivation on postural control. However, up to date, the effects of chronic sleep deficits, either in quantity or quality, have not been analyzed. Thirty healthy adults participated in the study that consisted of registering activity with a wrist actigraph for more than a week before performing a series of postural control tests. Sleep and circadian rhythm variables were correlated and the sum of activity of the least active 5-h period, L5, a rhythm variable, obtained the greater coefficient value with sleep quality variables (wake after sleep onset WASO and efficiency sleep). Cluster analysis was performed to classify subjects into two groups based on L5 (low and high). The balance tests scores used to asses postural control were measured using Biodex Balance System and were compared between the two groups with different sleep quality. The postural tests were divided into dynamic (platform tilt with eyes open, closed and cursor) and static (clinical test of sensory integration). The results showed that during the tests with eyes closed, the group with worse sleep quality had also worse postural control performance. Lack of vision impairs postural balance more deeply in subjects with chronic sleep inefficiency. Chronic poor sleep quality impairs postural control similarly to total sleep deprivation.

  14. Analysis of existing problems and countermeasures of quality control testing in clinical microbiology%临床微生物检验中质量控制存在问题与应对措施分析

    Institute of Scientific and Technical Information of China (English)

    刘荣华

    2016-01-01

    目的:分析临床微生物检验中质量控制所存在的问题并探讨应对的措施。方法使用不同方法对同一痰标本进行检测,以验证合适的方法对微生物检验的重要性;通过对比医院执行严格质量管理前后的药敏试验结果准确性,探讨质量管理对微生物检验的切实效果和具体的质量管理措施。结果通过对比,痰培养和痰培养+痰涂片对同一痰标本的检验阳性率比较差异有统计学意义(P<0.05)。医院执行严格质量管理前后的药敏试验结果准确性比较差异有统计学意义(P<0.05)。结论质量控制管理对于微生物检验至关重要,一般管理存在标本采样不规范、检验方法与检验环境不合理、检验和临床沟通不畅等问题,可以通过严格培训、规范操作规程、加强检验与临床沟通等措施提升临床微生物检验的质量。%Objective To investigate the clinical microbiological testing in quality control problems and the meas-ures to deal with. Methods Using different methods for the same sputum samples for testing, to verify the importance of appropriate methods for microbiological examination;perform susceptibility test results accuracy through strict quality con-trol before and after comparison of my hospital to investigate the quality of the management of microbiological testing of prac-tical effects and specific quality management measures. Results By contrast, sputum culture and sputum culture + spu-tum smear-positive rate for the same sputum test had significant differences (P<0. 05). Hospital perform susceptibility test results accuracy strict quality control before and after contrast were significantly different (P<0. 05). Conclusions Qual-ity control and management is essential for microbiological testing, the general management is not standardized specimen sampling, testing methods unreasonable, testing and clinical issues such as poor communication, can improve the

  15. Control by quality: proposition of a typology.

    Science.gov (United States)

    Pujo, P; Pillet, M

    The application of Quality tools and methods in industrial management has always had a fundamental impact on the control of production. It influences the behavior of the actors concerned, while introducing the necessary notions and formalizations, especially for production systems with little or no automation, which constitute a large part of the industrial activity. Several quality approaches are applied in the workshop and are implemented at the level of the control. In this paper, the authors present a typology of the various approaches that have successively influenced control, such as statistical process control, quality assurance, and continuous improvement. First the authors present a parallel between production control and quality organizational structure. They note the duality between control, which is aimed at increasing productivity, and quality, which aims to satisfy the needs of the customer. They also note the hierarchical organizational structure of these two systems of management with, at each level, the notion of a feedback loop. This notion is fundamental to any kind of decision making. The paper is organized around the operational, tactical, and strategic levels, by describing for each level the main methods and tools for control by quality. The overview of these tools and methods starts at the operational level, with the Statistical Process Control, the Taguchi technique, and the "six sigma" approach. On the tactical level, we find a quality system approach, with a documented description of the procedures introduced in the firm. The management system can refer here to Quality Assurance, Total Productive Maintenance, or Management by Total Quality. The formalization through procedures of the rules of decision governing the process control enhances the validity of these rules. This leads to the enhancement of their reliability and to their consolidation. All this counterbalances the human, intrinsically fluctuating, behavior of the control

  16. Six Sigma Quality Management System and Design of Risk-based Statistical Quality Control.

    Science.gov (United States)

    Westgard, James O; Westgard, Sten A

    2017-03-01

    Six sigma concepts provide a quality management system (QMS) with many useful tools for managing quality in medical laboratories. This Six Sigma QMS is driven by the quality required for the intended use of a test. The most useful form for this quality requirement is the allowable total error. Calculation of a sigma-metric provides the best predictor of risk for an analytical examination process, as well as a design parameter for selecting the statistical quality control (SQC) procedure necessary to detect medically important errors. Simple point estimates of sigma at medical decision concentrations are sufficient for laboratory applications.

  17. 21 CFR 862.1660 - Quality control material (assayed and unassayed).

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Quality control material (assayed and unassayed... Test Systems § 862.1660 Quality control material (assayed and unassayed). (a) Identification. A quality... that may arise from reagent or analytical instrument variation. A quality control material (assayed...

  18. Automated RNA Sample Quality Control

    OpenAIRE

    Borg, Solange; Salowsky, Ruediger; Inche, Adam; Connelly, Matthew; Boland, Dierdre; Padmanabanv, Arunkumar; Graf, Eva; Liu, Melissa Huang

    2014-01-01

    The Agilent 2200 TapeStation system provides a flexible solution for automated analysis of up to 96 samples using pre-packaged reagents and minimal manual handling. Here we present a new assay – the RNA ScreenTape assay – to enable robust quantification and quality analysis of Total RNA samples from both eukaryotic and prokaryotic sources from 100 pg/μl to 500 ng/μl. The new assay additionally benefits from the ability to provide separation of contaminant genomic DNA allowing more accurate pu...

  19. NIF Projects Controls and Information Systems Software Quality Assurance Plan

    Energy Technology Data Exchange (ETDEWEB)

    Fishler, B

    2011-03-18

    Quality achievement for the National Ignition Facility (NIF) and the National Ignition Campaign (NIC) is the responsibility of the NIF Projects line organization as described in the NIF and Photon Science Directorate Quality Assurance Plan (NIF QA Plan). This Software Quality Assurance Plan (SQAP) is subordinate to the NIF QA Plan and establishes quality assurance (QA) activities for the software subsystems within Controls and Information Systems (CIS). This SQAP implements an activity level software quality assurance plan for NIF Projects as required by the LLNL Institutional Software Quality Assurance Program (ISQAP). Planned QA activities help achieve, assess, and maintain appropriate quality of software developed and/or acquired for control systems, shot data systems, laser performance modeling systems, business applications, industrial control and safety systems, and information technology systems. The objective of this SQAP is to ensure that appropriate controls are developed and implemented for management planning, work execution, and quality assessment of the CIS organization's software activities. The CIS line organization places special QA emphasis on rigorous configuration control, change management, testing, and issue tracking to help achieve its quality goals.

  20. Net analyte signal based statistical quality control

    NARCIS (Netherlands)

    Skibsted, E.T.S.; Boelens, H.F.M.; Westerhuis, J.A.; Smilde, A.K.; Broad, N.W.; Rees, D.R.; Witte, D.T.

    2005-01-01

    Net analyte signal statistical quality control (NAS-SQC) is a new methodology to perform multivariate product quality monitoring based on the net analyte signal approach. The main advantage of NAS-SQC is that the systematic variation in the product due to the analyte (or property) of interest is sep

  1. Quality or Control? Management in Higher Education

    Science.gov (United States)

    Milliken, John; Colohan, Gerry

    2004-01-01

    Over the past fifteen years the rationale, organisational infrastructure and delivery of social policy in Britain have undergone radical transformation. Whereas efficiency was the key word of the 1980s, quality was the touchstone of the 1990s and quality control with accountability has become the management philosophy of the new millennium.…

  2. Rules of thumb to increase the software quality through testing

    Science.gov (United States)

    Buttu, M.; Bartolini, M.; Migoni, C.; Orlati, A.; Poppi, S.; Righini, S.

    2016-07-01

    The software maintenance typically requires 40-80% of the overall project costs, and this considerable variability mostly depends on the software internal quality: the more the software is designed and implemented to constantly welcome new changes, the lower will be the maintenance costs. The internal quality is typically enforced through testing, which in turn also affects the development and maintenance costs. This is the reason why testing methodologies have become a major concern for any company that builds - or is involved in building - software. Although there is no testing approach that suits all contexts, we infer some general guidelines learned during the Development of the Italian Single-dish COntrol System (DISCOS), which is a project aimed at producing the control software for the three INAF radio telescopes (the Medicina and Noto dishes, and the newly-built SRT). These guidelines concern both the development and the maintenance phases, and their ultimate goal is to maximize the DISCOS software quality through a Behavior-Driven Development (BDD) workflow beside a continuous delivery pipeline. We consider different topics and patterns; they involve the proper apportion of the tests (from end-to-end to low-level tests), the choice between hardware simulators and mockers, why and how to apply TDD and the dependency injection to increase the test coverage, the emerging technologies available for test isolation, bug fixing, how to protect the system from the external resources changes (firmware updating, hardware substitution, etc.) and, eventually, how to accomplish BDD starting from functional tests and going through integration and unit tests. We discuss pros and cons of each solution and point out the motivations of our choices either as a general rule or narrowed in the context of the DISCOS project.

  3. Quality Control Guidelines for SAM Chemical Methods

    Science.gov (United States)

    Learn more about quality control guidelines and recommendations for the analysis of samples using the chemistry methods listed in EPA's Selected Analytical Methods for Environmental Remediation and Recovery (SAM).

  4. Quality Control Guidelines for SAM Biotoxin Methods

    Science.gov (United States)

    Learn more about quality control guidelines and recommendations for the analysis of samples using the pathogen methods listed in EPA's Selected Analytical Methods for Environmental Remediation and Recovery (SAM).

  5. Quality Control Guidelines for SAM Radiochemical Methods

    Science.gov (United States)

    Learn more about quality control guidelines and recommendations for the analysis of samples using the radiochemistry methods listed in EPA's Selected Analytical Methods for Environmental Remediation and Recovery (SAM).

  6. Quality Control Guidelines for SAM Pathogen Methods

    Science.gov (United States)

    Learn more about quality control guidelines and recommendations for the analysis of samples using the biotoxin methods listed in EPA's Selected Analytical Methods for Environmental Remediation and Recovery (SAM).

  7. Quality Control Approaches for Chinese Herbal Medicines

    Institute of Scientific and Technical Information of China (English)

    YUAN Hai-long; ZHANG Tian-tian; XIAO Xiao-he

    2011-01-01

    The current official quality control approaches meet the challenges from the complexity of herbal medicines.In fact,any herbal medicines containing numerous unknown components,its curative effect usually depends on the whole of herbal medicines,so it is impossible and unnecessary to qualitatively and quantitatively study every component.By investigating the limitations of current quality control approaches for herbal medicines and the difference and similarity in the chemical substantial style as well as quality control pattern of herbal medicines,a new quality control approach for Chinese herbal medicines should be explored and designed.The combination approach of chemical analysis with bioassay is promising to be developed and employed in order to ensure the safety and efficacy of Chinese herbal medicines.

  8. Quality Controlled Local Climatological Data (QCLCD) Publication

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Quality Controlled Local Climatological Data (QCLCD) contains summaries from major airport weather stations that include a daily account of temperature extremes,...

  9. External quality control for embryology laboratories.

    Science.gov (United States)

    Castilla, Jose Antonio; Ruiz de Assín, Rafael; Gonzalvo, Maria Carmen; Clavero, Ana; Ramírez, Juan Pablo; Vergara, Francisco; Martínez, Luis

    2010-01-01

    Participation in external quality control (EQC) programmes is recommended by various scientific societies. Results from an EQC programme for embryology laboratories are presented. This 5-year programme consisted of the annual delivery of (i) materials to test toxicity and (ii) a DVD/CD-ROM with images of zygotes and embryos on days 2 and 3, on the basis of which the participants were asked to judge the embryo quality and to take a clinical decision. A high degree of agreement was considered achieved when over 75% of the laboratories produced similar classifications. With respect to the materials analysed, the specificity was 68% and the sensitivity was 83%. Concerning embryo classification, the proportion of embryos on which a high degree of agreement was achieved increased during this period from 35% to 55%. No improvement was observed in the degree of agreement on the clinical decision to be taken. Day-3 embryos produced a higher degree of agreement (58%) than did day-2 embryos (32%) (Pembryology laboratories.

  10. Quality control for quantitative geophysical logging

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Sang Kyu; Hwang, Se Ho; Hwang, Hak Soo; Park, In Hwa [Korea Institute of Geology Mining and Materials, Taejon (Korea)

    1998-12-01

    Despite the great availability of geophysical data obtained from boreholes, the interpretation is subject to significant uncertainties. More accurate data with less statistical uncertainties should require an employment of more quantitative techniques in log acquisition and interpretation technique. The long-term objective of this project is the development of techniques in both quality control of log measurement and the quantitative interpretation. In the first year, the goals of the project will include establishing the procedure of log acquisition using various tests, analysing the effect of logging velocity change on the logging data, examining the repeatability and reproducibility, analyzing of filtering effect on the log measurements, and finally the zonation and the correlation of single-and inter-well log data. For the establishment of logging procedure, we have tested the multiple factors affecting the accuracy in depth. The factors are divided into two parts: human and mechanical. These factors include the zero setting of depth, the calculation of offset for the sonde, the stretching effect of cable, and measuring wheel accuracy. We conclude that the error in depth setting results primarily from human factor, and also in part from the stretching of cable. The statistical fluctuation of log measurements increases according to increasing the logging speed for the zone of lower natural gamma. Thus, the problem related with logging speed is a trifling matter in case of the application of resources exploration, the logging speed should run more slowly to reduce the statistical fluctuation of natural gamma with lithologic correlation in mind. The repeatability and reproducibility of logging measurements are tested. The results of repeatability test for the natural gamma sonde are qualitatively acceptable in the reproducibility test, the errors occurs in logging data between two operators and successive trials. We conclude that the errors result from the

  11. TECHNIQUES ABOUT DIRECT OPTIMIZING CONTROL OF GREEN SAND QUALITY*

    Institute of Scientific and Technical Information of China (English)

    2002-01-01

    Green sand casting is still a main method in the world at present and it is very significant to develop the technology of controlling green sand quality. A new concept, from contents test to contents control, is advanced. In order to realize the new idea, a new method to on-line test active clay and moisture of green sand - double powers energizing alternately (DPEA) method is put forwards. The principle of the new method is to energize standard sand sample with AC and DC powers and to test the electric parameters, and then, to calculate active clay and moisture of green sand by using artificial neural network (ANN). Based on this new method, a direct optimizing system for controlling green sand quality is developed. Techniques about testing and controlling methods, hardware and software are discussed.

  12. Developing methods of controlling quality costs

    Directory of Open Access Journals (Sweden)

    Gorbunova A. V.

    2017-01-01

    Full Text Available The article examines issues of managing quality costs, problems of applying economic methods of quality control, implementation of progressive methods of quality costs management in enterprises with the view of improving the efficiency of their evaluation and analysis. With the aim of increasing the effectiveness of the cost management mechanism, authors introduce controlling as a tool of deviation analysis from the standpoint of the process approach. A list of processes and corresponding evaluation criteria in the quality management system of enterprises is introduced. Authors also introduce the method of controlling quality costs and propose it for the practical application, which allows them to determine useful and unnecessary costs at the existing operating plant. Implementing the proposed recommendations in the system of cost management at an enterprise will allow to improve productivity of processes operating and reduce wasted expense on the quality of the process on the basis of determining values of useful and useless costs of quality according to criteria of processes functioning in the system of quality management.

  13. Quality control in FISH as part of a laboratory's quality management system.

    Science.gov (United States)

    Hastings, Ros

    2010-01-01

    Quality control in the laboratory setting requires the establishment of a quality management system (QMS) that covers training, standard operating procedures, internal quality control, validation of tests, and external quality assessment (EQA). Laboratory accreditation through inspection by an external body is also desirable as this provides an effective procedure for assuring quality and also reassures the patient that the laboratory is working to acceptable international standards. The implementation of fluorescence in situ hybridisation (FISH) in the routine diagnostic laboratory requires rigorous quality control with attention to when it is appropriate to apply the technology, a systematic approach to the validation of probes, policies and procedures documenting the analytical validity of all FISH tests performed, technical procedures involved, and a comprehensive means of reporting results. Knowledge of the limitations of any FISH test is required in relation to the probe and/or tissue being examined, since errors of analysis and interpretation can result in incorrect patient management. A structured QMS with internal quality control and regular audits will minimise the error rate.

  14. Network-based production quality control

    Science.gov (United States)

    Kwon, Yongjin; Tseng, Bill; Chiou, Richard

    2007-09-01

    This study investigates the feasibility of remote quality control using a host of advanced automation equipment with Internet accessibility. Recent emphasis on product quality and reduction of waste stems from the dynamic, globalized and customer-driven market, which brings opportunities and threats to companies, depending on the response speed and production strategies. The current trends in industry also include a wide spread of distributed manufacturing systems, where design, production, and management facilities are geographically dispersed. This situation mandates not only the accessibility to remotely located production equipment for monitoring and control, but efficient means of responding to changing environment to counter process variations and diverse customer demands. To compete under such an environment, companies are striving to achieve 100%, sensor-based, automated inspection for zero-defect manufacturing. In this study, the Internet-based quality control scheme is referred to as "E-Quality for Manufacturing" or "EQM" for short. By its definition, EQM refers to a holistic approach to design and to embed efficient quality control functions in the context of network integrated manufacturing systems. Such system let designers located far away from the production facility to monitor, control and adjust the quality inspection processes as production design evolves.

  15. Examining the Impact of Covariates on Anchor Tests to Ascertain Quality over Time in a College Admissions Test

    Science.gov (United States)

    Wiberg, Marie; von Davier, Alina A.

    2017-01-01

    We propose a comprehensive procedure for the implementation of a quality control process of anchor tests for a college admissions test with multiple consecutive administrations. We propose to examine the anchor tests and their items in connection with covariates to investigate if there was any unusual behavior in the anchor test results over time…

  16. Analysis the Influencing Factors of Food Microbiological Testing and Quality Control Ways%食品微生物检验的影响因素及质控方式初探

    Institute of Scientific and Technical Information of China (English)

    何丽英; 刘志军

    2016-01-01

    微生物指标是食品安全的重要评价指标。在检验时,应明确食品微生物检验的影响因素,其中包括人为因素、环境与设施、药品配制及样品的采集、管理与操作等,同时采取有效的质控方式来提高食品微生物检验数据的真实有效性。%The index is a key indicator of microbial food safety. At the time of inspection, it should be clearly inlfuencing factors of food microbiological testing, including human factors, environment and facilities, pharmaceutical preparation and sample collection, management and other operations, and to take effective way to improve quality control in food microbiology real test data effectively sex.

  17. 10 CFR 26.167 - Quality assurance and quality control.

    Science.gov (United States)

    2010-01-01

    ... acceptable values are obtained for the known calibrators, those values will be used to calculate sample data... performing specific gravity tests: (i) The refractometer must report and display the specific gravity to four... initial and confirmatory specific gravity tests must have a calibrator or control at 1.0000; and (iii) The...

  18. Harmonisation Initiatives of Copernicus Data Quality Control

    Science.gov (United States)

    Vescovi, F. D.; Lankester, T.; Coleman, E.; Ottavianelli, G.

    2015-04-01

    The Copernicus Space Component Data Access system (CSCDA) incorporates data contributions from a wide range of satellite missions. Through EO data handling and distribution, CSCDA serves a set of Copernicus Services related to Land, Marine and Atmosphere Monitoring, Emergency Management and Security and Climate Change. The quality of the delivered EO products is the responsibility of each contributing mission, and the Copernicus data Quality Control (CQC) service supports and complements such data quality control activities. The mission of the CQC is to provide a service of quality assessment on the provided imagery, to support the investigation related to product quality anomalies, and to guarantee harmonisation and traceability of the quality information. In terms of product quality control, the CQC carries out analysis of representative sample products for each contributing mission as well as coordinating data quality investigation related to issues found or raised by Copernicus users. Results from the product analysis are systematically collected and the derived quality reports stored in a searchable database. The CQC service can be seen as a privileged focal point with unique comparison capacities over the data providers. The comparison among products from different missions suggests the need for a strong, common effort of harmonisation. Technical terms, definitions, metadata, file formats, processing levels, algorithms, cal/val procedures etc. are far from being homogeneous, and this may generate inconsistencies and confusion among users of EO data. The CSCDA CQC team plays a significant role in promoting harmonisation initiatives across the numerous contributing missions, so that a common effort can achieve optimal complementarity and compatibility among the EO data from multiple data providers. This effort is done in coordination with important initiatives already working towards these goals (e.g. INSPIRE directive, CEOS initiatives, OGC standards, QA4EO

  19. Quality control of parasitology stool examination in Tabriz clinical laboratories

    Directory of Open Access Journals (Sweden)

    shahram Khademvatan

    2011-06-01

    Full Text Available The purpose of quality control program was to make doctors and laboratory personnel trust in laboratory results and consequently increasing confidence in laboratory achievements. The quality assurance means raising the level of quality in all tests that lead to raising the level of work efficiency and laboratories including minimum expense for society and minimum time for lab personnel. This study aimed to assess and determine the accuracy and precision of results in Tabriz medical diagnostic laboratories. Materials and Methods: In this retrospective study, 790 stool samples were selected randomly and tested by standard methods.Student t- test, SPSS software and sensitivity and accuracy formulas were used for data analysis. Results: The sensitivity was 62%, 22% and 8% with 95% confidence intervals for worm's eggs, protozoan cysts and trophozoite detection respectively. Conclusion: To elevate quality assurance in clinical diagnostic laboratory, monitoring and check of the laboratories by standard methods continually should be done.

  20. MICROBIOLOGICAL TESTING OF SELECTED CONFECTIONERY PRODUCTS QUALITY

    Directory of Open Access Journals (Sweden)

    Ľubomíra Juhaniaková

    2014-02-01

    Full Text Available The aim of this work was to determine microbiological quality and water activity of confectionery products as corpus of desserts, stuffing cakes and finished cakes. In confectionery products microbiological parameters: total count of bacteria, coliforms bacteria, mesophilic aerobic bacteria, yeasts, microscopic filamentous fungi, counts of Staphylococcus aureus and Salmonella spp. were observed. These confectionery products were evaluated: 5 corpus of Kremeš, 5 stuffing of Kremeš and 5 Venček cake. For microbiological tests 15 samples of confectionery products were used. The numbers of total count of bacteria ranged from 2.9 to 3.65 log CFU.g-1, the number of mesophilic aerobic bacteria ranged from 2.00 to 3.28 log CFU.g-1, coliforms bacteria in confectionery products ranged from 0.00 to 3.15 CFU.g-1, number of yeasts ranged from 0.00 to 3.30 log CFU.g-1and the number of microscopic fungi ranged from 0.00 to 2.90 CFU.g-1. None of the samples showed any growth of coliforms bacteria, Staphylococcus aureus and Salmonella spp. From microscopic fungi were isolated genera Alternaria, Aspergillus and Penicillium. Eight from fifteen investigated samples of confectionary products were in accordance with the Codex Alimentarius of the Slovak Republic. The lowest water activity was found in Kremeš corpus samples (0.953 and higher in Venček samples (0.973.

  1. Protein quality control in the nucleus

    DEFF Research Database (Denmark)

    Nielsen, Sofie V.; Poulsen, Esben Guldahl; Rebula, Caio A.

    2014-01-01

    to aggregate, cells have evolved several elaborate quality control systems to deal with these potentially toxic proteins. First, various molecular chaperones will seize the misfolded protein and either attempt to refold the protein or target it for degradation via the ubiquitin-proteasome system...... to be particularly active in protein quality control. Thus, specific ubiquitin-protein ligases located in the nucleus, target not only misfolded nuclear proteins, but also various misfolded cytosolic proteins which are transported to the nucleus prior to their degradation. In comparison, much less is known about...... these mechanisms in mammalian cells. Here we highlight recent advances in our understanding of nuclear protein quality control, in particular regarding substrate recognition and proteasomal degradation....

  2. 30 CFR 28.31 - Quality control plans; contents.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Quality control plans; contents. 28.31 Section... PROTECTION FOR TRAILING CABLES IN COAL MINES Quality Control § 28.31 Quality control plans; contents. (a) Each quality control plan shall contain provisions for the management of quality, including:...

  3. Frontiers in statistical quality control 11

    CERN Document Server

    Schmid, Wolfgang

    2015-01-01

    The main focus of this edited volume is on three major areas of statistical quality control: statistical process control (SPC), acceptance sampling and design of experiments. The majority of the papers deal with statistical process control, while acceptance sampling and design of experiments are also treated to a lesser extent. The book is organized into four thematic parts, with Part I addressing statistical process control. Part II is devoted to acceptance sampling. Part III covers the design of experiments, while Part IV discusses related fields. The twenty-three papers in this volume stem from The 11th International Workshop on Intelligent Statistical Quality Control, which was held in Sydney, Australia from August 20 to August 23, 2013. The event was hosted by Professor Ross Sparks, CSIRO Mathematics, Informatics and Statistics, North Ryde, Australia and was jointly organized by Professors S. Knoth, W. Schmid and Ross Sparks. The papers presented here were carefully selected and reviewed by the scientifi...

  4. Quality Control and Reference Guidelines for CLSI Broth Microdilution Method (M38-A Document) for Susceptibility Testing of Anidulafungin against Molds▿

    Science.gov (United States)

    Espinel-Ingroff, A.; Fothergill, A.; Ghannoum, M.; Manavathu, E.; Ostrosky-Zeichner, L.; Pfaller, M. A.; Rinaldi, M. G.; Schell, W.; Walsh, T. J.

    2007-01-01

    The CLSI (formerly NCCLS) M38-A document for antifungal susceptibility testing of filamentous fungi does not describe guidelines for echinocandins. A multicenter study (eight centers) evaluated inter- and intralaboratory reproducibilities of two reading times (24 and 48 h or 48 and 72 h) and two end points (MICs and minimum effective concentrations [MECs]) for evaluating anidulafungin against molds. Anidulafungin MICs (≥50% inhibition) and MECs (morphological hyphal changes) were determined for seven Aspergillus isolates (four species) and one isolate each of Fusarium moniliforme, Fusarium solani, and Paecilomyces variotii and for two Scedosporium apiospermum isolates. The inter- and intralaboratory reproducibilities of 10 replicate tests performed in each laboratory on 10 different days for each isolate was 100% at 24 h (MECs, ≤0.015 μg/ml) for six Aspergillus and P. variotii isolates. The reproducibility was 94 to 96.7% at 72 h (MECs, 1 to 8 μg/ml) for S. apiospermum and 96.7 to 97.5% at 48 h (MICs, ≥32 μg/ml) for both Fusarium isolates. Introduction of these identified optimum testing conditions for anidulafungin into future versions of the M38 document is warranted. PMID:17475760

  5. Statistical quality control a loss minimization approach

    CERN Document Server

    Trietsch, Dan

    1999-01-01

    While many books on quality espouse the Taguchi loss function, they do not examine its impact on statistical quality control (SQC). But using the Taguchi loss function sheds new light on questions relating to SQC and calls for some changes. This book covers SQC in a way that conforms with the need to minimize loss. Subjects often not covered elsewhere include: (i) measurements, (ii) determining how many points to sample to obtain reliable control charts (for which purpose a new graphic tool, diffidence charts, is introduced), (iii) the connection between process capability and tolerances, (iv)

  6. The quality control theory of aging

    Directory of Open Access Journals (Sweden)

    Warren Ladiges

    2014-05-01

    Full Text Available The quality control (QC theory of aging is based on the concept that aging is the result of a reduction in QC of cellular systems designed to maintain lifelong homeostasis. Four QC systems associated with aging are 1 inadequate protein processing in a distressed endoplasmic reticulum (ER; 2 histone deacetylase (HDAC processing of genomic histones and gene silencing; 3 suppressed AMPK nutrient sensing with inefficient energy utilization and excessive fat accumulation; and 4 beta-adrenergic receptor (BAR signaling and environmental and emotional stress. Reprogramming these systems to maintain efficiency and prevent aging would be a rational strategy for increased lifespan and improved health. The QC theory can be tested with a pharmacological approach using three well-known and safe, FDA-approved drugs: 1 phenyl butyric acid, a chemical chaperone that enhances ER function and is also an HDAC inhibitor, 2 metformin, which activates AMPK and is used to treat type 2 diabetes, and 3 propranolol, a beta blocker which inhibits BAR signaling and is used to treat hypertension and anxiety. A critical aspect of the QC theory, then, is that aging is associated with multiple cellular systems that can be targeted with drug combinations more effectively than with single drugs. But more importantly, these drug combinations will effectively prevent, delay, or reverse chronic diseases of aging that impose such a tremendous health burden on our society.

  7. QUALITY CONTROL OF SOME TRADITIONAL MEAT PRODUCTS

    Directory of Open Access Journals (Sweden)

    S. DOBRINAS

    2014-03-01

    Full Text Available In this paper, we present the characterization of six traditional meat products: smoked file, smoked bacon, pork sausages, sausage prepared from swine’s entrails, pork pastrami, sheep sausages. Organoleptic tests (the aspect and shape, the aspect of freshly cut in the section, smell, taste and consistency, physico-chemical and microbiological determinations (NTG, Salmonella, Listeria monocytogenes and Escherichia coli were performed. These analyzes are a part of quality control that must be done in order to obtain a certificate from the Ministry of Agriculture for a traditional product. After identification of H2S and starch and according to fat oxidation degree it was concluded that analyzed samples didn’t contain counterfeiters and all parameters analyzed are within the maximum limits allowed by law. Considering all the procedures for manufacturing, characteristics of raw and auxiliary materials, organoleptic properties of final products analyzed in this study, it can be concluded that analyzed meat specialties meet the requirements of Ministry Order no. 690/28.09.2004 for the traditional products certification.

  8. The quality control theory of aging.

    Science.gov (United States)

    Ladiges, Warren

    2014-01-01

    The quality control (QC) theory of aging is based on the concept that aging is the result of a reduction in QC of cellular systems designed to maintain lifelong homeostasis. Four QC systems associated with aging are 1) inadequate protein processing in a distressed endoplasmic reticulum (ER); 2) histone deacetylase (HDAC) processing of genomic histones and gene silencing; 3) suppressed AMPK nutrient sensing with inefficient energy utilization and excessive fat accumulation; and 4) beta-adrenergic receptor (BAR) signaling and environmental and emotional stress. Reprogramming these systems to maintain efficiency and prevent aging would be a rational strategy for increased lifespan and improved health. The QC theory can be tested with a pharmacological approach using three well-known and safe, FDA-approved drugs: 1) phenyl butyric acid, a chemical chaperone that enhances ER function and is also an HDAC inhibitor, 2) metformin, which activates AMPK and is used to treat type 2 diabetes, and 3) propranolol, a beta blocker which inhibits BAR signaling and is used to treat hypertension and anxiety. A critical aspect of the QC theory, then, is that aging is associated with multiple cellular systems that can be targeted with drug combinations more effectively than with single drugs. But more importantly, these drug combinations will effectively prevent, delay, or reverse chronic diseases of aging that impose such a tremendous health burden on our society.

  9. Quality control chart for crushed granite concrete

    Directory of Open Access Journals (Sweden)

    Ewa E. DESMOND

    2016-07-01

    Full Text Available A chart for assessing in-situ grade (strength of concrete, has been developed in this study. Four grades of concrete after the Nigerian General Specification for Roads and bridges (NGSRB-C20, C25, C30 and C35, is studied at different water-cement ratios for medium and high slump range. The concrete mixes are made from crushed granite rock as coarse aggregate with river sand as fine aggregate. Compression test on specimens are conducted at curing age of 1, 3, 7, 14, 21, 28 and 56 days. Results on concrete workability from slump values, and water-cement ratios revealed that specimens with lower water-cement ratio were less workable but had higher strength, compared to mixes with higher water cement ratio. A simple algorithm using nonlinear regression analysis performed on each experimental data set produced Strength-Age (S-A curves which were used to establish a quality control chart. The accuracy of these curves were evaluated by computing average absolute error (AAS, the error of estimate (EoE and the average absolute error of estimate (Abs EoE for each concrete mix. These were done based on the actual average experimental strengths to measure how close the predicted values are to the experimental data set. The absolute average error of estimate (Abs. EoE recorded was less than ±10% tolerance zone for concrete works.

  10. 浅谈床旁即时检验的质量控制%Briefly discuss on quality control of bedside testing

    Institute of Scientific and Technical Information of China (English)

    张冬梅

    2010-01-01

    POCT(point-of-care testing)即床旁即时检验也称现场快速检验,是近几年悄然兴起的一种极具潜力的检测技术,它具有更新、更快、更准确、更方便的特点,在医院急诊、社区医疗服务以及慢性病患者的自我检测中发挥了重要作用.

  11. 重型动力触探在振冲施工质量控制及检测中的应用%Application of Heavy Dynamic Penetration in the Quality Control of Vibro Stone Column Construction and the Testing

    Institute of Scientific and Technical Information of China (English)

    李庆跃; 李晓力; 肖普

    2013-01-01

      振冲复合地基以其低成本、高效率等优势已经广泛的应用于水利水电、火电、工民建、石化、交通、市政、铁路等行业的地基处理中。振冲进行地基处理的规模和速度日新月异,使得施工过程中的质量控制变得非常重要。通过对重型动力触探在振冲碎石桩工程中的应用,论述了重型动力触探在振冲施工质量控制及检测中的重要性及适用性,并总结了其在工程中的应用经验。%With the advantages of low cost and high efficiency, vibrated composite foundation has been widely used in water conservancy and hydropower, thermal power, civil engineering fitting, petrochemical, transportation, municipal, railways and other industries.The construction quality control becomes very important.By the application of heavy dynamic penetra-tion in the vibro stone column project, the paper discusses the significance and applicability of heavy dynamic penetration in quality control and the testing of vibro stone column, and sums up the experiences.

  12. Cursor Control Device Test Battery

    Science.gov (United States)

    Holden, Kritina; Sandor, Aniko; Pace, John; Thompson, Shelby

    2013-01-01

    The test battery was developed to provide a standard procedure for cursor control device evaluation. The software was built in Visual Basic and consists of nine tasks and a main menu that integrates the set-up of the tasks. The tasks can be used individually, or in a series defined in the main menu. Task 1, the Unidirectional Pointing Task, tests the speed and accuracy of clicking on targets. Two rectangles with an adjustable width and adjustable center- to-center distance are presented. The task is to click back and forth between the two rectangles. Clicks outside of the rectangles are recorded as errors. Task 2, Multidirectional Pointing Task, measures speed and accuracy of clicking on targets approached from different angles. Twenty-five numbered squares of adjustable width are arranged around an adjustable diameter circle. The task is to point and click on the numbered squares (placed on opposite sides of the circle) in consecutive order. Clicks outside of the squares are recorded as errors. Task 3, Unidirectional (horizontal) Dragging Task, is similar to dragging a file into a folder on a computer desktop. Task 3 requires dragging a square of adjustable width from one rectangle and dropping it into another. The width of each rectangle is adjustable, as well as the distance between the two rectangles. Dropping the square outside of the rectangles is recorded as an error. Task 4, Unidirectional Path Following, is similar to Task 3. The task is to drag a square through a tunnel consisting of two lines. The size of the square and the width of the tunnel are adjustable. If the square touches any of the lines, it is counted as an error and the task is restarted. Task 5, Text Selection, involves clicking on a Start button, and then moving directly to the underlined portion of the displayed text and highlighting it. The pointing distance to the text is adjustable, as well as the to-be-selected font size and the underlined character length. If the selection does not

  13. Quality Control of Trichinella Testing at the Slaughterhouse Laboratory: Evaluation of the Use of a 400-Micrometer-Mesh-Size Sieve in the Magnetic Stirrer Method.

    Science.gov (United States)

    Franssen, Frits; van Andel, Esther; Swart, Arno; van der Giessen, Joke

    2016-02-01

    The performance of a 400-μm-mesh-size sieve (sieve400) has not previously been compared with that of a 180-μm-mesh-size sieve (sieve180). Using pork samples spiked with 0 to 10 Trichinella muscle larvae and an artificial digestion method, sieve performance was evaluated for control of Trichinella in meat-producing animals. The use of a sieve400 resulted in 12% lower larval counts, 147% more debris, and 28% longer counting times compared with the use of a sieve180. Although no false-negative results were obtained, prolonged counting times with the sieve400 may have an impact on performance in a high-throughput environment such as a slaughterhouse laboratory. Based on our results, the sieve180 remains the sieve of choice for Trichinella control in meat in slaughterhouse laboratories, according to the European Union reference method (European Commission regulation 2075/2005). Furthermore, the results of the present study contribute to the discussion of harmonization of meat inspection requirements among countries.

  14. Quality by control: Towards model predictive control of mammalian cell culture bioprocesses.

    Science.gov (United States)

    Sommeregger, Wolfgang; Sissolak, Bernhard; Kandra, Kulwant; von Stosch, Moritz; Mayer, Martin; Striedner, Gerald

    2017-07-01

    The industrial production of complex biopharmaceuticals using recombinant mammalian cell lines is still mainly built on a quality by testing approach, which is represented by fixed process conditions and extensive testing of the end-product. In 2004 the FDA launched the process analytical technology initiative, aiming to guide the industry towards advanced process monitoring and better understanding of how critical process parameters affect the critical quality attributes. Implementation of process analytical technology into the bio-production process enables moving from the quality by testing to a more flexible quality by design approach. The application of advanced sensor systems in combination with mathematical modelling techniques offers enhanced process understanding, allows on-line prediction of critical quality attributes and subsequently real-time product quality control. In this review opportunities and unsolved issues on the road to a successful quality by design and dynamic control implementation are discussed. A major focus is directed on the preconditions for the application of model predictive control for mammalian cell culture bioprocesses. Design of experiments providing information about the process dynamics upon parameter change, dynamic process models, on-line process state predictions and powerful software environments seem to be a prerequisite for quality by control realization. © 2017 The Authors. Biotechnology Journal published by WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  15. CRM软件测试质量控制过程的效度分析%The Effectiveness Survey on Quality Control for CRM Software Testing

    Institute of Scientific and Technical Information of China (English)

    窦文章; 胡丹

    2009-01-01

    统计过程控制((statistical process control,SPC)模型是一种质量控制方法.本文以莱CBM跨国企业案例为例,将SPC技术应用于CRM软件测试过程,通过使用SPC技术来监控测试过程的稳定性,分析此过程的技术满足度,以及可能造成过程失控的归属原因.研究结论是,将统计过程控制技术和CRM软件的测试质量管理进行了有机结合,将实现对测试过程的有效质量控制,并提高企业的质量管理水平.

  16. Extracellular quality control in the epididymis

    Institute of Scientific and Technical Information of China (English)

    Gail A. Cornwall; H. Henning von Horsten; Douglas Swartz; Seethal Johnson; Kim Chau; Sandra Whelly

    2007-01-01

    The epididymal lumen represents a unique extracellular environment because of the active sperm maturation process that takes place within its confines. Although much focus has been placed on the interaction of epididymal secretory proteins with spermatozoa in the lumen, very little is known regarding how the complex epididymal milieu as a whole is maintained, including mechanisms to prevent or control proteins that may not stay in their native folded state following secretion. Because some misfolded proteins can form cytotoxic aggregate structures known as amyloid, it is likely that control/surveillance mechanisms exist within the epididymis to protect against this process and allow sperm maturation to occur. To study protein aggregation and to identify extracellular quality control mechanisms in the epididymis, we used the cystatin family of cysteine protease inhibitors, including cystatin-related epididymal spermatogenic and cystatin C as molecular models because both proteins have inherent properties to aggregate and form amyloid. In this chapter, we present a brief summary of protein aggregation by the amyloid pathway based on what is known from other organ systems and describe quality control mechanisms that exist intracellularly to control protein misfolding and aggregation. We then present a summary of our studies of cystatinrelated epididymal spermatogenic (CRES) oligomerization within the epididymal lumen, including studies suggesting that transglutaminase cross-linking may be one mechanism of extracellular quality control within the epididymis.

  17. Outsourcing University Degrees: Implications for Quality Control

    Science.gov (United States)

    Edwards, Julie; Crosling, Glenda; Edwards, Ron

    2010-01-01

    Education institutions worldwide have and continue to seek opportunities to spread their offerings abroad. While the provision of courses to students located overseas through partner institutions has many advantages, it raises questions about quality control that are not as applicable to other forms of international education. This paper uses a…

  18. Outsourcing University Degrees: Implications for Quality Control

    Science.gov (United States)

    Edwards, Julie; Crosling, Glenda; Edwards, Ron

    2010-01-01

    Education institutions worldwide have and continue to seek opportunities to spread their offerings abroad. While the provision of courses to students located overseas through partner institutions has many advantages, it raises questions about quality control that are not as applicable to other forms of international education. This paper uses a…

  19. The Key-point Analysis of Comparison Testing, Quality Control and Data Verification of CEMS%烟气CEMS比对监测及质量控制、数据审核要点解析

    Institute of Scientific and Technical Information of China (English)

    郭卫兴; 胡敏; 刘启贞

    2009-01-01

    On the basis of the problems during the operation of CEMS of stationary source, the comparison tes-ting, quality control and data verification of CEMS are analyzed. The data of CEMS, validated by these three methods, can be used by the ministry of environmental protection.%针对目前烟气CEMS在实际运行过程中遇到的问题,本文从比对监测、质量控制以及数据审核三个方面作了详细分析,通过验收比对监测、日常的监督比对监测、有效数据的审核、烟气CEMS的质量保证和质量控制措施,烟气CEMS产生的数据可作为各地环保管理部门环境监督管理的依据.

  20. Reinventing Teaching and Testing: Quality Learning for Quality Employment.

    Science.gov (United States)

    Cooke, Brian P.

    To succeed in today's competitive global markets, organizations are hiring responsible problem solvers and collaborative "associates" who improve productivity, assure quality service, and contribute creatively. These organizations demand employees who are skilled at learning to learn, listening, communicating, problem solving, teamwork,…

  1. Statistical quality control through overall vibration analysis

    Science.gov (United States)

    Carnero, M. a. Carmen; González-Palma, Rafael; Almorza, David; Mayorga, Pedro; López-Escobar, Carlos

    2010-05-01

    The present study introduces the concept of statistical quality control in automotive wheel bearings manufacturing processes. Defects on products under analysis can have a direct influence on passengers' safety and comfort. At present, the use of vibration analysis on machine tools for quality control purposes is not very extensive in manufacturing facilities. Noise and vibration are common quality problems in bearings. These failure modes likely occur under certain operating conditions and do not require high vibration amplitudes but relate to certain vibration frequencies. The vibration frequencies are affected by the type of surface problems (chattering) of ball races that are generated through grinding processes. The purpose of this paper is to identify grinding process variables that affect the quality of bearings by using statistical principles in the field of machine tools. In addition, an evaluation of the quality results of the finished parts under different combinations of process variables is assessed. This paper intends to establish the foundations to predict the quality of the products through the analysis of self-induced vibrations during the contact between the grinding wheel and the parts. To achieve this goal, the overall self-induced vibration readings under different combinations of process variables are analysed using statistical tools. The analysis of data and design of experiments follows a classical approach, considering all potential interactions between variables. The analysis of data is conducted through analysis of variance (ANOVA) for data sets that meet normality and homoscedasticity criteria. This paper utilizes different statistical tools to support the conclusions such as chi squared, Shapiro-Wilks, symmetry, Kurtosis, Cochran, Hartlett, and Hartley and Krushal-Wallis. The analysis presented is the starting point to extend the use of predictive techniques (vibration analysis) for quality control. This paper demonstrates the existence

  2. Uniformity microsprinkler irrigation system using statistical quality control

    OpenAIRE

    Maurício Guy de Andrade; Marcio Antonio Vilas Boas; Jair Antonio Cruz Siqueira; Mireille Sato; Jonathan Dieter; Eliane Hermes; Erivelto Mercante

    2017-01-01

    ABSTRACT: The objective of this study was to evaluate the use of statistical quality control tools in the analysis of the uniformity of a microsprinkler irrigation system. For the analysis of irrigation Christiansen uniformity coefficient (CUC) and the distribution uniformity coefficient (DU) were statistically analyzed by means of the Shewhart control charts and process capability index (Cp). For the experiment 25 tests were carried out with a single micro sprinkler and subsequently seven di...

  3. A fast and simple dose-calibrator-based quality control test for the radionuclidic purity of cyclotron-produced 99mTc

    Science.gov (United States)

    Tanguay, J.; Hou, X.; Esquinas, P.; Vuckovic, M.; Buckley, K.; Schaffer, P.; Bénard, F.; Ruth, T. J.; Celler, A.

    2015-11-01

    Cyclotron production of {{}99\\text{m}} Tc through the 100Mo(p,2n){{}99\\text{m}} Tc reaction channel is actively being investigated as an alternative to reactor-based 99Mo generation by nuclear fission of 235U. Like most radioisotope production methods, cyclotron production of {{}99\\text{m}} Tc will result in creation of unwanted impurities, including Tc and non-Tc isotopes. It is important to measure the amounts of these impurities for release of cyclotron-produced {{}99\\text{m}} Tc (CPTc) for clinical use. Detection of radioactive impurities will rely on measurements of their gamma (γ) emissions. Gamma spectroscopy is not suitable for this purpose because the overwhelming presence of {{}99\\text{m}} Tc and the count-rate limitations of γ spectroscopy systems preclude fast and accurate measurement of small amounts of impurities. In this article we describe a simple and fast method for measuring γ emission rates from radioactive impurities in CPTc. The proposed method is similar to that used to identify 99Mo breakthrough in generator-produced {{}99\\text{m}} Tc: one dose calibrator (DC) reading of a CPTc source placed in a lead shield is followed by a second reading of the same source in air. Our experimental and theoretical analysis show that the ratio of DC readings in lead to those in air are linearly related to γ emission rates from impurities per MBq of {{}99\\text{m}} Tc over a large range of clinically-relevant production conditions. We show that estimates of the γ emission rates from Tc impurities per MBq of {{}99\\text{m}} Tc can be used to estimate increases in radiation dose (relative to pure {{}99\\text{m}} Tc) to patients injected with CPTc-based radiopharmaceuticals. This enables establishing dosimetry-based clinical-release criteria that can be tested using commercially-available dose calibrators. We show that our approach is highly sensitive to the presence of {{}93\\text{g}} Tc, {{}93\\text{m}} Tc, {{}94\\text{g}} Tc, {{}94\\text{m}} Tc

  4. Quality Control Guidelines for Amphotericin B, Itraconazole, Posaconazole, and Voriconazole Disk Diffusion Susceptibility Tests with Nonsupplemented Mueller-Hinton Agar (CLSI M51-A Document) for Nondermatophyte Filamentous Fungi▿

    Science.gov (United States)

    Espinel-Ingroff, A.; Canton, E.; Fothergill, A.; Ghannoum, M.; Johnson, E.; Jones, R. N.; Ostrosky-Zeichner, L.; Schell, W.; Gibbs, D. L.; Wang, A.; Turnidge, J.

    2011-01-01

    Although Clinical and Laboratory Standards Institute (CLSI) disk diffusion assay standard conditions are available for susceptibility testing of filamentous fungi (molds) to antifungal agents, quality control (QC) disk diffusion zone diameter ranges have not been established. This multicenter study documented the reproducibility of tests for one isolate each of five molds (Paecilomyces variotii ATCC MYA-3630, Aspergillus fumigatus ATCC MYA-3626, A. flavus ATCC MYA-3631, A. terreus ATCC MYA-3633, and Fusarium verticillioides [moniliforme] ATCC MYA-3629) and Candida krusei ATCC 6258 by the CLSI disk diffusion method (M51-A document). The zone diameter ranges for selected QC isolates were as follows: P. variotii ATCC MYA-3630, amphotericin B (15 to 24 mm), itraconazole (20 to 31 mm), and posaconazole (33 to 43 mm); A. fumigatus ATCC MYA-3626, amphotericin B (18 to 25 mm), itraconazole (11 to 21 mm), posaconazole (28 to 35 mm), and voriconazole (25 to 33 mm); and C. krusei, amphotericin B (18 to 27 mm), itraconazole (18 to 26 mm), posaconazole (28 to 38 mm), and voriconazole (29 to 39 mm). Due to low testing reproducibility, zone diameter ranges were not proposed for the other three molds. PMID:21543581

  5. Tests for evaluating the physiological quality of pitaya seeds

    National Research Council Canada - National Science Library

    Thiago Alberto Ortiz; Aline Moritz; Lúcia Sadayo Assari Takahashi; Mariana Ragassi Urbano

    2015-01-01

    .... Thus, this study aimed to develop methodologies for conducting tests of germination, accelerated aging, and electrical conductivity for the evaluation of the physiological quality of pitaya seeds...

  6. The consistency approach for the quality control of vaccines.

    Science.gov (United States)

    Hendriksen, Coenraad; Arciniega, Juan L; Bruckner, Lukas; Chevalier, Michel; Coppens, Emmanuelle; Descamps, Johan; Duchêne, Michel; Dusek, David Michael; Halder, Marlies; Kreeftenberg, Hans; Maes, Alexandrine; Redhead, Keith; Ravetkar, Satish D; Spieser, Jean-Marc; Swam, Hanny

    2008-01-01

    Current lot release testing of conventional vaccines emphasizes quality control of the final product and is characterized by its extensive use of laboratory animals. This report, which is based on the outcome of an ECVAM (European Centre for Validation of Alternative Methods, Institute for Health and Consumer Protection, European Commission Joint Research Centre, Ispra, Italy) workshop, discusses the concept of consistency testing as an alternative approach for lot release testing. The consistency approach for the routine release of vaccines is based upon the principle that the quality of vaccines is a consequence of a quality system and of consistent production of lots with similar characteristics to those lots that have been shown to be safe and effective in humans or the target species. The report indicates why and under which circumstances this approach can be applied, the role of the different stakeholders, and the need for international harmonization. It also gives recommendations for its implementation.

  7. 42 CFR 84.41 - Quality control plans; contents.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Quality control plans; contents. 84.41 Section 84... AND HEALTH RESEARCH AND RELATED ACTIVITIES APPROVAL OF RESPIRATORY PROTECTIVE DEVICES Quality Control § 84.41 Quality control plans; contents. (a) Each quality control plan shall contain provisions for...

  8. 30 CFR 28.30 - Quality control plans; filing requirements.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Quality control plans; filing requirements. 28... PROTECTION FOR TRAILING CABLES IN COAL MINES Quality Control § 28.30 Quality control plans; filing... part, each applicant shall file with MSHA a proposed quality control plan which shall be designed...

  9. 42 CFR 84.40 - Quality control plans; filing requirements.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Quality control plans; filing requirements. 84.40... Control § 84.40 Quality control plans; filing requirements. As a part of each application for approval or... proposed quality control plan which shall be designed to assure the quality of respiratory...

  10. 21 CFR 211.22 - Responsibilities of quality control unit.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 4 2010-04-01 2010-04-01 false Responsibilities of quality control unit. 211.22... Personnel § 211.22 Responsibilities of quality control unit. (a) There shall be a quality control unit that... have been fully investigated. The quality control unit shall be responsible for approving or...

  11. Online subjective testing for consumer-photo quality evaluation

    Science.gov (United States)

    Saad, Michele A.; McKnight, Patrick; Quartuccio, Jacob; Nicholas, David; Jaladi, Ramesh; Corriveau, Philip

    2016-07-01

    We take a look at crowdsourcing for subjective image quality evaluation using real image stimuli with nonsimulated distortions. Our aim is to scale the task of subjectively rating images while ensuring maximal data validity and accuracy. While previous work has begun to explore crowdsourcing for quality assessment, it has either used images that are not representative of popular consumer scenarios or used crowdsourcing to collect data without comparison to experiments in a controlled environment. Here, we address the challenges imposed by the highly variable online environment, using stimuli that are subtle and more complex than has traditionally been used in quality assessment experiments. In a series of experiments, we vary different design parameters and demonstrate how they impact the subjective responses obtained. Of the parameters examined are stimulus display mode, study length, stimulus habituation, and content homogeneity/heterogeneity. Our method was tested on a database that was rated in a laboratory test previously. Once our design parameters were chosen, we rated a database of consumer photographs and are making this data available to the research community.

  12. 40 CFR 75.21 - Quality assurance and quality control requirements.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 16 2010-07-01 2010-07-01 false Quality assurance and quality control... assurance and quality control requirements. (a) Continuous emission monitoring systems. The owner or... system according to the quality assurance and quality control procedures in appendix B of this part....

  13. On the Optimization of the Quality of Language Tests

    Institute of Scientific and Technical Information of China (English)

    张艳梅

    2008-01-01

    <正>Language tests are frequently used as devices to evaluate language learning and teaching; therefore,we must be concerned about the quality—reliability and validity—of our tests.Many researches have showed that the quality of language tests has been decreased owing to the misuse of multiple-choice items.It is necessary to reduce the percentage of objective items in the tests,but what is more important is test writers’ professional skills which can directly affect the quality of the tests. This essay focuses on how to optimize the quality of language tests through the training for test writers. It has become quite urgent and important now,which should involve in familiarizing the writers with basic testing theories,purposes and types of testing,and main specific testing methods.

  14. Control of Bank Consolidated Financial Statements Quality

    Directory of Open Access Journals (Sweden)

    Margarita S. Ambarchyan

    2013-01-01

    Full Text Available The author presents the multiple linear regression model of bank consolidated financial statements quality. The article considers six characteristics that can be used to estimate the level of bank consolidated financial statements quality. The multiple linear regression model was developed, using the results of point-based system of consolidated financial statements of thirty European bank and financial groups on the basis of the developed characteristics. The author offers to use the characteristic significance factor in the process of consolidated financial statements appraisal by points. The constructed regression model is checked on accuracy and statistical significance. The model can be used by internal auditors and financial analytics as an instrument for bank and non-bank consolidated financial statements quality control

  15. Quality Control and Assurance for Coagulation Tests

    Institute of Scientific and Technical Information of China (English)

    彭黎明

    2006-01-01

    @@ The coagulation laboratory aids the clinician in assessing not only the bleeding patient but also the thrombotic patient. The techniques of coagulation laboratory are used to evaluate not only the coagulation system but also the anti-coagulation system, fibrinolytic system,platelet and vascular endothelial function. Enzymes, inhibitors, plasma factors and co-factors, cellular release products, and cell receptors can be measured in coagulation laboratory.

  16. The results of quality control of national autoantibody testing in 2010%2010年全国自身抗体检测质量控制总结

    Institute of Scientific and Technical Information of China (English)

    谢瑶; 吴琨; 彭清林; 张荣富; 王国春

    2011-01-01

    Objective To investigate the quality of autoantibody testing around the whole country.Methods Laboratories that perform autoantibody testing were recruited by letters or telephone communications.The auto-antibodies examined by the quality-control survey included anti-nuclear antibody (ANA),anti-double-stranded DNA (anti-dsDNA) antibody,anti-extractable nuclear antigens (anti-ENA),antimitochondria antibody (AMA),anti-smooth muscle antibody (ASMA),and anti-citrulline antibody (CCP).Each autoantibody was tested for 3 samples,so 15 samples were tested in total.Sample distribution and data analysis were double-blinded.Qualitative interpretation,staining patterns were evaluated by IIF.The agreement with qualitative interpretation for each specimen was evaluated by ELISA,and Immuno-Blot/Dot-Blot.Results One hundred and eight laboratories participated in this study.The testing methods included indirect immumofluorescence (IIF),immuno-Blot (IB),Dot-Blot (DB),double diffusion method (DID),enzymelinked immunosorbent assay (ELISA),chemo-illuminescent assay,Dot-immunogold filtration assay.The accuracy rates were 82%,83%,95%,96%,86%,respectively for ANA,anti-dsDNA,AMA,ASMA,and anti-CCP antibody.Anti-ENA were further divided into anti-SNP,anti-Sm,anti-SSA,anti-SSB,anti-Scl-70 subgroups,and the accuracy rates were 84%,95%,98%,98%,88%,respectively.The distribution of quantitative values by different laboratories for ANA (by IIF),anti-dsDNA,anti-CCP antibody (by ELISA) varied remarkably.Conclusion Hospitals that enrolled in the survey and the items involved for quality control were increasing year by year.The accurate rates of ANA,anti-dsDNA in this survey were similar to the past national quality control surveys,the quality of AMA/ASMA,anti-CCP antibodies test was better than that of the past surveys,but the quality of anti-ENA antibodies test needs to be improved.%目的 了解2010年我国自身抗体检测的现状,促进我国自身抗

  17. Testing CAN for Robotic Control

    NARCIS (Netherlands)

    Ferdinando, Hany

    2004-01-01

    This project elaborates link drivers for the ADSP-21992. They are link drivers for Analog to Digital Converter (ADC), Encoder Interface Unit (EIU), Auxiliary PWM and the Control Area Network (CAN) bus. All link drivers are derived from the abstract LinkDriver class available in the CT Library. These

  18. Mitochondrial quality control in cardiac diseases.

    Directory of Open Access Journals (Sweden)

    Juliane Campos

    2016-10-01

    Full Text Available Disruption of mitochondrial homeostasis is a hallmark of cardiac diseases. Therefore, maintenance of mitochondrial integrity through different surveillance mechanisms is critical for cardiomyocyte survival. In this review, we discuss the most recent findings on the central role of mitochondrial quality control processes including regulation of mitochondrial redox balance, aldehyde metabolism, proteostasis, dynamics and clearance in cardiac diseases, highlighting their potential as therapeutic targets.

  19. Towards quality control of food using terahertz

    Science.gov (United States)

    Ung, B. S.-Y.; Fischer, B. M.; Ng, B. W.-H.; Abbott, D.

    2007-12-01

    Terahertz radiation or T-rays, show promise in quality control of food products. As T-rays are inherently sensitive to water, they are very suitable for moisture detection. This proves to be a valuable asset in detecting the moisture content of dried food, a critical area for some products. As T-rays are transparent to plastics, food additives can also be probed through the packaging, providing checks against a manufacturer's claims, such as the presence of certain substances in foods.

  20. An analysis of the mathematics school examination test quality

    Directory of Open Access Journals (Sweden)

    Hadi Sutrisno

    2016-11-01

    Full Text Available This research aims to describe: (1 the quality of mathematics school examination test of the Junior High School for the academic year 2015/2016 in Kabupaten Bangkalan based on qualitative analysis of tests item, (2 the quality of mathematics school examination test of Junior High School for the academic year 2015/2016 in Kabupaten Bangkalan based on quantitative analysis of test items, and (3 the test equating on mathematics school examination test for the academic year of 2015/2016 of Junior High School in Kabupaten Bangkalan. A test is said to be quality if it fulfills validity, reliability, and it has good characteristic. A test is said to be equivalent to another if the test scores of one test can be exchanged with the scores of another test. The data is taken from school examination script accompanied with the answer sheets of students. Qualitative data analysis was conducted with the help of experts judgement. Quantitative data analysis was conducted with Classical Test Theory by Iteman and Item Response Theory by BilogMG. These programs are used to find out the test quality quantitatively. In order to analyze the equivalence between series of tests, item-characteristic curves were used. These curves were drawn by Geogebra. The research result shows: (1 qualitatively, the test plan quality of mathematics school examination test is quite good. Meanwhile, the school exam quality is quite good and not so good, (2 quantitatively, the school examination test quality is good, and (3 equating, based on the item-characteristic curves, the school examination tests is equal.

  1. Quality control analytical methods: strategies to ensure a robust quality-control microbiology program.

    Science.gov (United States)

    Griffiths, Tricia; Connors, Anne

    2013-01-01

    As the regulatory environment for compounding pharmacies continues to evolve, facilities can take immediate steps to strengthen their quality-control microbiology and environmental monitoring programs. Robust programs that are timely, comprehensive, and effective will minimize risk and help support positive patient outcomes. This article provides a roadmap for putting in place a robust quality-control microbiology program in the face of United States Pharmacopeia Chapter 797 standards, and highlights several technologies for environmental monitoring that support a successful program.

  2. Remote control missile model test

    Science.gov (United States)

    Allen, Jerry M.; Shaw, David S.; Sawyer, Wallace C.

    1989-01-01

    An extremely large, systematic, axisymmetric body/tail fin data base was gathered through tests of an innovative missile model design which is described herein. These data were originally obtained for incorporation into a missile aerodynamics code based on engineering methods (Program MISSILE3), but can also be used as diagnostic test cases for developing computational methods because of the individual-fin data included in the data base. Detailed analysis of four sample cases from these data are presented to illustrate interesting individual-fin force and moment trends. These samples quantitatively show how bow shock, fin orientation, fin deflection, and body vortices can produce strong, unusual, and computationally challenging effects on individual fin loads. Comparisons between these data and calculations from the SWINT Euler code are also presented.

  3. Improving Quality of Seal Leak Test Product using Six Sigma

    Science.gov (United States)

    Luthfi Malik, Abdullah; Akbar, Muhammad; Irianto, Dradjad

    2016-02-01

    Seal leak test part is a polyurethane material-based product. Based on past data, defect level of this product was 8%, higher than the target of 5%. Quality improvement effort was done using six sigma method that included phases of define, measure, analyse, improve, and control. In the design phase, a Delphi method was used to identify factors that were critical to quality. In the measure phase, stability and process capability was measured. Fault tree analysis (FTA) and failure mode and effect analysis (FMEA) were used in the next phase to analize the root cause and to determine the priority issues. Improve phase was done by compiling, selecting, and designing alternative repair. Some improvement efforts were identified, i.e. (i) making a checklist for maintenance schedules, (ii) making written reminder form, (iii) modifying the SOP more detail, and (iv) performing a major service to the vacuum machine. To ensure the continuity of improvement efforts, some control activities were executed, i.e. (i) controlling, monitoring, documenting, and setting target frequently, (ii) implementing reward and punishment system, (iii) adding cleaning tool, and (iv) building six sigma organizational structure.

  4. Standard practice for strain controlled thermomechanical fatigue testing

    CERN Document Server

    American Society for Testing and Materials. Philadelphia

    2010-01-01

    1.1 This practice covers the determination of thermomechanical fatigue (TMF) properties of materials under uniaxially loaded strain-controlled conditions. A “thermomechanical” fatigue cycle is here defined as a condition where uniform temperature and strain fields over the specimen gage section are simultaneously varied and independently controlled. This practice is intended to address TMF testing performed in support of such activities as materials research and development, mechanical design, process and quality control, product performance, and failure analysis. While this practice is specific to strain-controlled testing, many sections will provide useful information for force-controlled or stress-controlled TMF testing. 1.2 This practice allows for any maximum and minimum values of temperature and mechanical strain, and temperature-mechanical strain phasing, with the restriction being that such parameters remain cyclically constant throughout the duration of the test. No restrictions are placed on en...

  5. Quality assurance of absorbed energy in Charpy impact test

    Science.gov (United States)

    Rocha, C. L. F.; Fabricio, D. A. K.; Costa, V. M.; Reguly, A.

    2016-07-01

    In order to ensure the quality assurance and comply with standard requirements, an intralaboratory study has been performed for impact Charpy tests, involving two operators. The results based on ANOVA (Analysis of Variance) and Normalized Error statistical techniques pointed out that the execution of the tests is appropriate, because the implementation of quality assurance methods showed acceptable results.

  6. Quality of routine spirometry tests in Dutch general practices.

    NARCIS (Netherlands)

    Schermer, T.R.J.; Crockett, A.J.; Poels, P.J.P.; Dijke, J.J. van; Akkermans, R.P.; Vlek, H.F.; Pieters, W.R.

    2009-01-01

    BACKGROUND: Spirometry is an indispensable tool for diagnosis and monitoring of chronic airways disease in primary care. AIM: To establish the quality of routine spirometry tests in general practice, and explore associations between test quality and patient characteristics. DESIGN OF STUDY: Analysis

  7. A Rule-Based System for Test Quality Improvement

    Science.gov (United States)

    Costagliola, Gennaro; Fuccella, Vittorio

    2009-01-01

    To correctly evaluate learners' knowledge, it is important to administer tests composed of good quality question items. By the term "quality" we intend the potential of an item in effectively discriminating between skilled and untrained students and in obtaining tutor's desired difficulty level. This article presents a rule-based e-testing system…

  8. Classroom Test Writing: Effects of Item Format on Test Quality.

    Science.gov (United States)

    Torabi-Parizi, Rosa; Campbell, Noma Jo

    1982-01-01

    Investigates the effects of varying the placement of blanks and the number of options available in multiple-choice items on the reliability of fifth-grade students' scores. Results indicate that scores on three-choice item tests were not less reliable than scores on four-choice item tests. A similar finding was found regarding the placement of…

  9. Process and quality verification controls for solid propellant manufacturing

    Science.gov (United States)

    Rogers, C. J.

    1983-01-01

    It is pointed out that in-process tests to verify quality and detect discrepant propellant which could compromise motor performance are essential elements of the solid composite propellant manufacturing process. The successful performance of the 260SL-1 and 260SL-2 motors aptly verified the controls used for manufacturing the propellant. The present investigation is concerned with the selected control parameters, and their relationships to composition and final propellant properties. Control performance is evaluated by comparison with processing data experienced in the manufacture of the propellant for the 260SL-1 motor. It is found that the in-process quality verification controls utilized in the propellant manufacturing process for the 260-in. diameter motor contributed significantly to the confidence of successful and predictable motor performance.

  10. Process and quality verification controls for solid propellant manufacturing

    Science.gov (United States)

    Rogers, C. J.

    1983-01-01

    It is pointed out that in-process tests to verify quality and detect discrepant propellant which could compromise motor performance are essential elements of the solid composite propellant manufacturing process. The successful performance of the 260SL-1 and 260SL-2 motors aptly verified the controls used for manufacturing the propellant. The present investigation is concerned with the selected control parameters, and their relationships to composition and final propellant properties. Control performance is evaluated by comparison with processing data experienced in the manufacture of the propellant for the 260SL-1 motor. It is found that the in-process quality verification controls utilized in the propellant manufacturing process for the 260-in. diameter motor contributed significantly to the confidence of successful and predictable motor performance.

  11. Flight Test Approach to Adaptive Control Research

    Science.gov (United States)

    Pavlock, Kate Maureen; Less, James L.; Larson, David Nils

    2011-01-01

    The National Aeronautics and Space Administration s Dryden Flight Research Center completed flight testing of adaptive controls research on a full-scale F-18 testbed. The validation of adaptive controls has the potential to enhance safety in the presence of adverse conditions such as structural damage or control surface failures. This paper describes the research interface architecture, risk mitigations, flight test approach and lessons learned of adaptive controls research.

  12. Applying GPS to check horizontal control quality

    Directory of Open Access Journals (Sweden)

    Jakub Vincent

    2004-03-01

    Full Text Available GPS technologies can also be used for check quality in available horizontal point set with coordinates CJ of the frame S-JTSK. When survey and setting-out tasks should be performed in certain area, one can found in it allways some points of the fundamental and detail state controls. To use these points for some actual aims, it is necessary to investigate their compatibility (among the point mark positions and the point coordinate of control points. This can be done using GPS surveying that may be at the same time employed to determine the new point in the relevant area.Principle of quality investigatingf an existing control is founded on determination of point coordinates CJt from GPS measurements. Then, based on discrepancies among the "official" netpoint coordinates CJ and coordinates CJt "given by GPS", it can be estimated the degree and the real compatibility dislocations in the network structure of the existing points.Realisation procedure for the introduced investigation is demonstrated on GPS checking (by SOKKIA STRATUS receivers horizontal control for reconstruction of a railway bridge on river Bodrog in East Slovakia.It can be shown from the results in Table 3, that points P3 and P7 are useless due to their incompatibility (inconsistency in the inspected point set. For other 7 points (Table 7 the average measure of incompatibility reads 9.8 mm that make possible applying these points for precise setting-out

  13. Adaptive quality control for multimedia communications

    Directory of Open Access Journals (Sweden)

    Santichai Chuaywong

    2008-01-01

    Full Text Available Multimedia communications are communications with several types of media, such as audio, video and data. The current Internet has some levels of capability to support multimedia communications, unfortunately, the QoS (Quality of Service is still challenging. A large number of QoS mechanisms has been proposed; however, the main concern is for low levels, e.g. layer 2 (Data Link or 3 (Transport. In this paper, mechanisms for control the quality of audio and video are proposed. G.723.1 and MPEG-4 are used as the audio and video codec respectively. The proposed algorithm for adaptive quality control of audio communication is based on forward error correction (FEC. In the case of video communication, the proposed algorithm adapts the value of key frame interval, which is an encoding parameter of MPEG-4. We evaluated our proposed algorithms by computer simulation. We have shown that, in most cases, the proposed scheme gained a higher throughput compared to other schemes.

  14. Quality Management of CERN Vacuum Controls

    CERN Document Server

    Antoniotti, F; Fortescue-Beck, E; Gama, J; Gomes, P; Le Roux, P; Pereira, H; Pigny, G

    2014-01-01

    The vacuum controls Section (TE-VSC-ICM) is in charge of the monitoring, maintenance and consolidation of the control systems of all accelerators and detectors in CERN; this represents 6 000 instruments distributed along 128 km of vacuum chambers, often of heterogeneous architectures and of diverse technical generations. In order to improve the efficiency of the services provided by ICM, to vacuum experts and to accelerator operators, a Quality Management Plan is being put into place. The first step was the standardization of the naming convention across different accelerators. The traceability of problems, requests, repairs, and other actions, has also been put into place (VTL). This was combined with the effort to identify each individual device by a coded label, and register it in a central database (MTF). Occurring in parallel, was the gathering of old documents and the centralization of information concerning architectures, procedures, equipment and settings (EDMS). To describe the topology of control c...

  15. Quality of Liver and Kideny Function Test

    African Journals Online (AJOL)

    GB

    Stress contributes to health problems worldwide. Its presence is felt in home, ... influenced by ethnic, cultural, and socioeconomic .... personal resources toward something else, such ... sample t-test, and univariate relationships between ..... Management Training on self image of ... Malaysia Journal Medicine Science 2011;.

  16. 10 CFR 72.162 - Test control.

    Science.gov (United States)

    2010-01-01

    ... 10 Energy 2 2010-01-01 2010-01-01 false Test control. 72.162 Section 72.162 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSING REQUIREMENTS FOR THE INDEPENDENT STORAGE OF SPENT NUCLEAR FUEL... Test control. The licensee, applicant for a license, certificate holder, and applicant for a CoC...

  17. Production Quality Control Of Microfluidic Chip Designs

    DEFF Research Database (Denmark)

    Calaon, Matteo; Hansen, Hans Nørgaard; Tosello, Guido

    2012-01-01

    -beam lithography. Subsequent nickel electroplating was employed to replicate the obtained geometries on the tool, which was used to mold on transparent polymer substrates the functional structures. To assess the critical factors affecting the replication quality throughout the different steps of the proposed...... process chain, test geometries were designed and produced on the side of the functional features. The so called “Finger Print” of the lithography and molding processes was qualitatively and quantitatively evaluated through scanning electron microscopy and atomic force microscopy respectively. The entire...

  18. Quality Control Analytical Methods: Method Validation.

    Science.gov (United States)

    Klang, Mark G; Williams, LaVonn A

    2016-01-01

    To properly determine the accuracy of a pharmaceutical product or compounded preparation, tests must be designed specifically for that evaluation. The procedures selected must be verified through a process referred to as method validation, an integral part of any good analytical practice. The results from a method validation procedure can be used to judge the quality, reliability, and consistency of analytical results. The purpose of this article is to deliver the message of the importance of validation of a pharmaceutical product or compounded preparation and to briefly discuss the results of a lack of such validation. Copyright© by International Journal of Pharmaceutical Compounding, Inc.

  19. Decant pump assembly and controls qualification testing - test report

    Energy Technology Data Exchange (ETDEWEB)

    Staehr, T.W., Westinghouse Hanford

    1996-05-02

    This report summarizes the results of the qualification testing of the supernate decant pump and controls system to be used for in-tank sludge washing in aging waste tank AZ-101. The test was successful and all components are qualified for installation and use in the tank.

  20. [Colonoscopy quality control as a requirement of colorectal cancer screening].

    Science.gov (United States)

    Quintero, Enrique; Alarcón-Fernández, Onofre; Jover, Rodrigo

    2013-11-01

    The strategies used in population-based colorectal screening strategies culminate in colonoscopy and consequently the success of these programs largely depends on the quality of this diagnostic test. The main factors to consider when evaluating quality are scientific-technical quality, safety, patient satisfaction, and accessibility. Quality indicators allow variability among hospitals, endoscopy units and endoscopists to be determined and can identify those not achieving recommended standards. In Spain, the working group for colonoscopy quality of the Spanish Society of Gastroenterology and the Spanish Society of Gastrointestinal Endoscopy have recently drawn up a Clinical Practice Guideline that contains the available evidence on the quality of screening colonoscopy, as well as the basic requirements that must be met by endoscopy units and endoscopists carrying out this procedure. The implementation of training programs and screening colonoscopy quality controls are strongly recommended to guarantee the success of population-based colorectal cancer screening. Copyright © 2013 Elsevier España, S.L. and AEEH y AEG. All rights reserved.

  1. [ROKO--computer-assisted roentgen quality control].

    Science.gov (United States)

    Schenk, G; Gfirtner, H

    1995-05-01

    To guarantee the quality of 30 x-ray machines and 8 photographic processors 24,000 data are collected yearly. A computer system is introduced (ROKO-Röntgenkonstanzprüfung) which helps to collect the monthly data easily and to measure on-line dose and voltage. If given tolerance values are exceeded acoustic and graphic warnings appear, a trend analysis is made to assure the correctness of the collected data, a generator to design the layout of check form facilitates the controlling and an on-line documentation for each x-ray machine is available. All these features help save time and money.

  2. Predictive control of speededness in adaptive testing

    NARCIS (Netherlands)

    van der Linden, Willem J.

    2009-01-01

    An adaptive testing method is presented that controls the speededness of a test using predictions of the test takers' response times on the candidate items in the pool. Two different types of predictions are investigated: posterior predictions given the actual response times on the items already

  3. Predictive Control of Speededness in Adaptive Testing

    Science.gov (United States)

    van der Linden, Wim J.

    2009-01-01

    An adaptive testing method is presented that controls the speededness of a test using predictions of the test takers' response times on the candidate items in the pool. Two different types of predictions are investigated: posterior predictions given the actual response times on the items already administered and posterior predictions that use the…

  4. Quality Assurance Tests of the CMS Endcap RPCs

    CERN Document Server

    Ahmed, Ijaz; Hamid Ansari, M; Irfan Asghar, M; Asghar, Sajjad; Awan, Irfan Ullah; Butt, Jamila; Hoorani, Hafeez R; Hussain, Ishtiaq; Khurshid, Taimoor; Muhammad, Saleh; Shahzad, Hassan; Aftab, Zia; Iftikhar, Mian; Khan, Mohammad Khalid; Saleh, M

    2008-01-01

    In this note, we have described the quality assurance tests performed for endcap Resistive Plate Chambers (RPCs) at two different sites, Pakistan Atomic Energy Commission (PAEC) and National Centre for Physics (NCP), in Pakistan. This paper describes various quality assurance tests both at the level of gas gaps and the chambers. The data has been obtained at different time windows during the large scale production of CMS RPCs of RE2/2 and RE2/3 type. In the quality assurance tests, we have investigated parameters like dark current, strip occupancy, cluster size and efficiency of RPCs.

  5. Distributed Sensor Architecture for Intelligent Control that Supports Quality of Control and Quality of Service

    Directory of Open Access Journals (Sweden)

    Jose-Luis Poza-Lujan

    2015-02-01

    Full Text Available This paper is part of a study of intelligent architectures for distributed control and communications systems. The study focuses on optimizing control systems by evaluating the performance of middleware through quality of service (QoS parameters and the optimization of control using Quality of Control (QoC parameters. The main aim of this work is to study, design, develop, and evaluate a distributed control architecture based on the Data-Distribution Service for Real-Time Systems (DDS communication standard as proposed by the Object Management Group (OMG. As a result of the study, an architecture called Frame-Sensor-Adapter to Control (FSACtrl has been developed. FSACtrl provides a model to implement an intelligent distributed Event-Based Control (EBC system with support to measure QoS and QoC parameters. The novelty consists of using, simultaneously, the measured QoS and QoC parameters to make decisions about the control action with a new method called Event Based Quality Integral Cycle. To validate the architecture, the first five Braitenberg vehicles have been implemented using the FSACtrl architecture. The experimental outcomes, demonstrate the convenience of using jointly QoS and QoC parameters in distributed control systems.

  6. Distributed Sensor Architecture for Intelligent Control that Supports Quality of Control and Quality of Service

    Science.gov (United States)

    Poza-Lujan, Jose-Luis; Posadas-Yagüe, Juan-Luis; Simó-Ten, José-Enrique; Simarro, Raúl; Benet, Ginés

    2015-01-01

    This paper is part of a study of intelligent architectures for distributed control and communications systems. The study focuses on optimizing control systems by evaluating the performance of middleware through quality of service (QoS) parameters and the optimization of control using Quality of Control (QoC) parameters. The main aim of this work is to study, design, develop, and evaluate a distributed control architecture based on the Data-Distribution Service for Real-Time Systems (DDS) communication standard as proposed by the Object Management Group (OMG). As a result of the study, an architecture called Frame-Sensor-Adapter to Control (FSACtrl) has been developed. FSACtrl provides a model to implement an intelligent distributed Event-Based Control (EBC) system with support to measure QoS and QoC parameters. The novelty consists of using, simultaneously, the measured QoS and QoC parameters to make decisions about the control action with a new method called Event Based Quality Integral Cycle. To validate the architecture, the first five Braitenberg vehicles have been implemented using the FSACtrl architecture. The experimental outcomes, demonstrate the convenience of using jointly QoS and QoC parameters in distributed control systems. PMID:25723145

  7. Development and Challenge of HIV/AIDS Testing Laboratory Network and Quality Assurance System in China

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    This paper describes the development and challenge of HIV/AIDS testing laboratory network and quality assurance system in China. At present, the HIV/AIDS testing laboratories includes three classes, the National AIDS Reference Laboratory, HIV/AIDS confirmatory laboratories and HIV/AIDS screening laboratories. All of them are accredited by the health authorities, and each class of laboratories take charge of their function strictly according to the "National Management of HIV/AIDS Detection (2006)". A complete quality assurance and quality control system for HIV/AIDS testing has been developed, which includes technical training, strict laboratory monitoring and approval,examination or proficiency testing on HIV/AIDS detection, and quality evaluation and supervision of HIV/AIDS diagnostic kits. Besides conduct the routine anti-HIV antibody test, more and more laboratories began to conduct other tests, such as CD4+ T lymphocyte cell counting, HIV viral load, HIV DNA PCR, genotyping, drug resistance, and HIV-1 recent infection test. The primary challenges faced by the HIV/AIDS testing laboratory network are in the areas of laboratory management and quality control. For example, the provincial PT program is inefficient, the internal quality control is conducted perfunctorily, personnel training can not met the needs of the workplace, which need to be improved.

  8. Test Code Quality and Its Relation to Issue Handling Performance

    NARCIS (Netherlands)

    Athanasiou, D.; Nugroho, A.; Visser, J.; Zaidman, A.

    2014-01-01

    Automated testing is a basic principle of agile development. Its benefits include early defect detection, defect cause localization and removal of fear to apply changes to the code. Therefore, maintaining high quality test code is essential. This study introduces a model that assesses test code qual

  9. The consistency approach for quality control of vaccines - a strategy to improve quality control and implement 3Rs.

    Science.gov (United States)

    De Mattia, Fabrizio; Chapsal, Jean-Michel; Descamps, Johan; Halder, Marlies; Jarrett, Nicholas; Kross, Imke; Mortiaux, Frederic; Ponsar, Cecile; Redhead, Keith; McKelvie, Jo; Hendriksen, Coenraad

    2011-01-01

    Current batch release testing of established vaccines emphasizes quality control of the final product and is often characterized by extensive use of animals. This report summarises the discussions of a joint ECVAM/EPAA workshop on the applicability of the consistency approach for routine release of human and veterinary vaccines and its potential to reduce animal use. The consistency approach is based upon thorough characterization of the vaccine during development and the principle that the quality of subsequent batches is the consequence of the strict application of a quality system and of a consistent production of batches. The concept of consistency of production is state-of-the-art for new-generation vaccines, where batch release is mainly based on non-animal methods. There is now the opportunity to introduce the approach into established vaccine production, where it has the potential to replace in vivo tests with non-animal tests designed to demonstrate batch quality while maintaining the highest quality standards. The report indicates how this approach may be further developed for application to established human and veterinary vaccines and emphasizes the continuing need for co-ordination and harmonization. It also gives recommendations for work to be undertaken in order to encourage acceptance and implementation of the consistency approach.

  10. Five Librarians Talk about Quality Control and the OCLC Database.

    Science.gov (United States)

    Helge, Brian; And Others

    1987-01-01

    Five librarians considered authorities on quality cataloging in the OCLC Online Union Catalog were interviewed to obtain their views on the current level of quality control in the OCLC database, the responsibilities of OCLC and individual libraries in improving the quality of records, and the consequences of quality control problems. (CLB)

  11. 7 CFR 58.141 - Alternate quality control program.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 3 2010-01-01 2010-01-01 false Alternate quality control program. 58.141 Section 58... Service 1 Quality Specifications for Raw Milk § 58.141 Alternate quality control program. When a plant has in operation an acceptable quality program, at the producer level, which is approved by...

  12. 新鲜血在自动化血沉分析仪TEST1EC质量控制中的应用%Quality control for erythrocyte sedimentation rate automated analyzer TEST1EC by fresh blood samples

    Institute of Scientific and Technical Information of China (English)

    杨肃文; 黄芳; 谢鑫友

    2005-01-01

    目的建立一种使用新鲜全血完成自动化血沉分析仪TEST1EC的质量控制方法.方法 EDTA-K3抗凝标本用自动化血沉分析仪ALIFAX-TEST1EC在4 h内测定血沉,同时用改良魏氏法测定血沉.计算日积累平均值,制作Levey-Jennings质控图.结果手工法与仪器法相关性良好(y=0.822X±2.774,r=0.993).以常规标本日积累均值及相应的标准差所作Levey-Jennings质控图,每天的日积累均值落在均值附近的±2s范围内(-x=19.80,s=3.07).结论建立新鲜全血标本的TEST1EC仪器质控方法有利于开展自动化血沉仪的质控,而且价格低廉,是值得推广的质控方法.

  13. Quality control of laser tailor welded blanks

    Science.gov (United States)

    Yan, Qi

    2008-03-01

    Tailor welded blanks were widely used in the automobile industry for their special advantages. A combination of different materials, thickness, and coatings could be welded together to form a blank for stamping car body panels. With the gradually growing consciousness on safety requirement of auto body structural, the business of laser tailor welded blanks is developing rapidly in China. Laser tailor welded blanks were just the semi products between steel factory and automobile manufacturers. As to the laser welding defects such as convexity and concavity, automobile industry had the strict requirement. In this paper, quality standard on laser tailor welded blanks were discussed. As for the production of laser tailor welded blanks, online quality control of laser tailor welded blanks was introduced. The image processing system for welding laser positioning and weld seam monitoring were used in the production of laser tailor welded blanks. The system analyzes images from the individual cameras and transmits the results to the machine control system via a CAN bus.

  14. Quality control for invasive cardiology: Holland.

    Science.gov (United States)

    Plokker, H W

    1996-10-01

    Although no official registration of indications, treatments and results in patients with coronary heart disease has taken place in Holland, the following authorities and commissions have introduced guidelines for quality control: the Dutch government, the Dutch Society of Cardiology, the Working Group on Interventional Cardiology and the health insurers. Until 1991, the right to perform coronary interventions was tied to a license issued by the Ministry of Health. New recommendations were delineated 5 years ago: at least 500 interventions must be annually performed by 5 interventional cardiologists, i.e. ca. 100 interventions annually per cardiologist. No interventional cardiology may be performed without an in-house cardiac surgery and vice versa. In a survey by the Dutch Society of Cardiology on the quality of the Dutch centers, PTCA-mortality was ca. 0.3%, infarction rate was ca. 2%. An emergency bypass operation was necessary in 1.0 to 1.6% of the cases; the surgical team was on immediate alert for 11% of the patients. Selection of patients without risk was deemed impossible. Despite objections by some members the Dutch Society of Cardiology, it was recommended that cardiac surgery and interventions should not be separated. Data from health insurers showed no inappropriate indications for PTCA. The DUCAT-study, which used the RAND criteria, showed PTCA indications to be correct in more than 90% of the cases. The Dutch government wants to control the expansion of PTCA centers, so it is no wonder that waiting lists are becoming longer.

  15. The evaluation of quality control on the new human IVF laboratory with mouse embryo testing%小鼠胚胎实验对新建人类体外受精实验室质量控制的评价

    Institute of Scientific and Technical Information of China (English)

    李弘; 袁彩霞; 秦琴; 宋海霞; 曹莹丽; 孙喜娟

    2013-01-01

    Objective To carry out the quality control of new human in vitro fertilization (IVF) laboratory,IVF of mouse were studied.Methods The gametes of mouse were got by surgery,treated by IVF and intracytoplasmic sperm injection(ICSI),the embryos were cultured for five days in vitro,fertility rate,grade 1-2 embryo rate and rate of cleavage to blastulas were investigated.Results 11 cycles of IVF were finished,271 eggs were gained,the fertility rate was 82.2% and grade 1-2 embryo rate was 91.3%,the rate of 2-cell was growing to blastulas was 85.3%.Ten cycle of ICSI were finished,206 oocytes at metaphase Ⅱ (M Ⅱ)were gained,the fertility rate was 84.5% and grade 1-2 embryo rate was 92.9%,the rate of 2-cell was growing to blastulas was 89.9%.Conclusion The quality control of culture condition in human IVF technology is tested by mouse embryo,the data accord with standards.%目的 利用小鼠体外受精技术对我院新建人类体外受精实验室进行质量控制.方法 手术获取小鼠配子,经体外受精或卵胞浆内单精子显微注射后,形成胚胎体外培养5d,观察受精率、优胚率、囊胚率.结果 本研究进行11个常规体外受精周期,取卵371枚,受精率82.2%(305枚),优胚率91.3% (274枚),2-细胞囊胚形成率85.3%(256枚);10个周期卵胞浆内单精子显微注射,取卵子206枚,受精率84.5%(174枚),优胚率92.9%(157枚),2-细胞囊胚形成率89.9%(152枚).结论 通过鼠胚实验对我科新建IVF实验室进行质量控制,结果符合标准.

  16. CT-based quality control of Laser Sintering of Polymers

    Directory of Open Access Journals (Sweden)

    Michele Pavan

    2016-11-01

    In this work a test artifact containing cylindrical elements with diameters in the range typically used in lightweight cellular structures is used to investigate the influence of features' size and printing orientation on the porosity and shape deviation of each feature. In order to assess the reproducibility of the process, several replicas of the test object are produced in polyamide-12 (PA12 using the same LS process conditions. An X-ray Computed Tomography (CT-based quality control approach, which uses both image processing of CT-slices and porosity analysis (porosity content, pores count and pores volume distributions is used to gather the information.

  17. Plastic optical fibre sensor for quality control in food industry

    Science.gov (United States)

    Novo, C.; Bilro, L.; Ferreira, R.; Alberto, N.; Antunes, P.; Leitão, C.; Nogueira, R.; Pinto, J. L.

    2013-05-01

    The present work addresses the need for new devices felt in the context of quality control, especially in the food industry. Due to the spectral dependence of the attenuation coefficient, a novel dual-parameter sensor for colour and refractive index was developed and tested. The sensor employs plastic optical fibres to measure the transmitted optical power in three measurement cells each with a different incident wavelength. The performance of the sensor was tested using several dyes at different concentrations and aqueous solutions of glycerine and ethanol. Results show that this technique allows the monitoring of refractive index and colour without cross-sensitivity.

  18. 46 CFR 164.019-13 - Production quality control requirements.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 6 2010-10-01 2010-10-01 false Production quality control requirements. 164.019-13....019-13 Production quality control requirements. (a) General. Each component manufacturer shall establish procedures for maintaining quality control of the materials used in production,...

  19. 7 CFR 275.21 - Quality control review reports.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 4 2010-01-01 2010-01-01 false Quality control review reports. 275.21 Section 275.21... Reporting on Program Performance § 275.21 Quality control review reports. (a) General. Each State agency shall submit reports on the performance of quality control reviews in accordance with the...

  20. 14 CFR 145.211 - Quality control system.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 3 2010-01-01 2010-01-01 false Quality control system. 145.211 Section 145...) SCHOOLS AND OTHER CERTIFICATED AGENCIES REPAIR STATIONS Operating Rules § 145.211 Quality control system. (a) A certificated repair station must establish and maintain a quality control system acceptable...

  1. 21 CFR 864.8625 - Hematology quality control mixture.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Hematology quality control mixture. 864.8625 Section 864.8625 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES... quality control mixture. (a) Identification. A hematology quality control mixture is a device used...

  2. 18 CFR 12.40 - Quality control programs.

    Science.gov (United States)

    2010-04-01

    ... 18 Conservation of Power and Water Resources 1 2010-04-01 2010-04-01 false Quality control... PROJECT WORKS Other Responsibilities of Applicant or Licensee § 12.40 Quality control programs. (a... meeting any requirements or standards set by the Regional Engineer. If a quality control program...

  3. A Systems Engineering Approach to Quality Assurance for Aerospace Testing

    Science.gov (United States)

    Shepherd, Christena C.

    2015-01-01

    On the surface, it appears that AS91001 has little to say about how to apply a Quality Management System (QMS) to major aerospace test programs (or even smaller ones). It also appears that there is little in the quality engineering Body of Knowledge (BOK)2 that applies to testing, unless it is nondestructive examination (NDE), or some type of lab or bench testing associated with the manufacturing process. However, if one examines: a) how the systems engineering (SE) processes are implemented throughout a test program; and b) how these SE processes can be mapped to the requirements of AS9100, a number of areas for involvement of the quality professional are revealed. What often happens is that quality assurance during a test program is limited to inspections of the test article; what could be considered a manufacturing al fresco approach. This limits the quality professional and is a disservice to the programs and projects, since there are a number of ways that quality can enhance critical processes, and support efforts to improve risk reduction, efficiency and effectiveness.

  4. Mechanical and dosimetric quality control for computer controlled radiotherapy treatment equipment.

    Science.gov (United States)

    Thompson, A V; Lam, K L; Balter, J M; McShan, D L; Martel, M K; Weaver, T A; Fraass, B A; Ten Haken, R K

    1995-05-01

    Modern computer controlled radiotherapy treatment equipment offers the possibility of delivering complex, multiple field treatments with minimal operator intervention, thus making multiple field conformal therapy practical. Conventional quality control programs are inadequate for this new technology, so new quality control procedures are needed. A reasonably fast, sensitive, and complete daily quality control program has been developed in our clinic that includes nearly automated mechanical as well as dosimetric tests. Automated delivery of these quality control fields is performed by the control system of the MM50 racetrack microtron, directed by the CCRS sequence processor [D. L. McShan and B. A. Fraass, Proceedings of the XIth International Conference on the use of computers in Radiation Therapy, 20-24 March 1994, Manchester, U.K. (North Western Medical Physics Department, Manchester, U.K., 1994), pp. 210-211], which controls the treatment process. The mechanical tests involve multiple irradiations of a single film to check the accuracy and reproducibility of the computer controlled setup of gantry and collimator angles, table orientation, collimator jaws, and multileaf collimator shape. The dosimetric tests, which involve multiple irradiations of an array of ionization chambers in a commercial dose detector (Keithly model 90100 Tracker System) rigidly attached to the head of the treatment gantry, check the output and symmetry of the treatment unit as a function of gantry and collimator angle and other parameters. For each of the dosimetric tests, readings from the five ionization chambers are automatically read out, stored, and analyzed by the computer, along with the geometric parameters of the treatment unit for that beam.(ABSTRACT TRUNCATED AT 250 WORDS)

  5. Integrated quality control architecture for multistage machining processes

    Science.gov (United States)

    Yang, Jie; Liu, Guixiong

    2010-12-01

    To solve problems concerning the process quality prediction control for the multistage machining processes, a integrated quality control architecture is proposed in this paper. First, a hierarchical multiple criteria decision model is established for the key process and the weight matrix method stratified is discussed. Predictive control of the manufacturing quality is not just for on-site monitoring and control layer, control layer in the enterprise, remote monitoring level of quality exists a variety of target predictive control demand, therefore, based on XML to achieve a unified description of manufacturing quality information, and in different source of quality information between agencies to achieve the transfer and sharing. This will predict complex global quality control, analysis and diagnosis data to lay a good foundation to achieve a more practical, open and standardized manufacturing quality with higher levels of information integration system.

  6. Managing Air Quality - Control Strategies to Achieve Air Pollution Reduction

    Science.gov (United States)

    Considerations in designing an effective control strategy related to air quality, controlling pollution sources, need for regional or national controls, steps to developing a control strategy, and additional EPA resources.

  7. Automated quality control in a file-based broadcasting workflow

    Science.gov (United States)

    Zhang, Lina

    2014-04-01

    Benefit from the development of information and internet technologies, television broadcasting is transforming from inefficient tape-based production and distribution to integrated file-based workflows. However, no matter how many changes have took place, successful broadcasting still depends on the ability to deliver a consistent high quality signal to the audiences. After the transition from tape to file, traditional methods of manual quality control (QC) become inadequate, subjective, and inefficient. Based on China Central Television's full file-based workflow in the new site, this paper introduces an automated quality control test system for accurate detection of hidden troubles in media contents. It discusses the system framework and workflow control when the automated QC is added. It puts forward a QC criterion and brings forth a QC software followed this criterion. It also does some experiments on QC speed by adopting parallel processing and distributed computing. The performance of the test system shows that the adoption of automated QC can make the production effective and efficient, and help the station to achieve a competitive advantage in the media market.

  8. Summary of the 2011 national autoantibody testing quality control%2011年全国多中心自身抗体检测质量控制结果分析

    Institute of Scientific and Technical Information of China (English)

    姚海红; 贾汝林; 贾园; 栗占国

    2012-01-01

    目的 了解2011年我国自身抗体检测的现状,以规范和促进我国自身抗体检测水平.方法 在全国范围内确定参与单位,质量控制的项目共计6项,15个标本,包括抗核抗体、抗双链DNA(dsDNA)抗体、抗可提取核抗原(ENA)抗体、抗线粒体抗体(AMA)、抗平滑肌抗体(ASMA)和抗环瓜氨酸肽(CCP)抗体,其中AMA、ASMA所用标本相同.标本发放及结果分析采取双盲的操作.共114个单位参加了此次质量控制活动,采用的检测方法包括间接免疫荧光法(IIF)、免疫印迹法(IB)、斑点法(DB)、免疫扩散法(DID)、酶联免疫吸附试验(ELISA)、化学发光法、胶体金斑点渗滤法等.结果 抗核抗体、抗dsDNA抗体、抗ENA抗体、AMA、ASMA、抗CCP抗体检测的正确率分别是98.0%、96.6%、89.5%、98.1%、92.1%和96.4%.其中抗RNP抗体、抗Sm抗体、抗SSA抗体、抗SSB抗体、抗Scl-70抗体的正确率分别是88.4%、96.8%、100%、100%和95.8%.不同实验室间IIF法检测抗核抗体的滴度差异较大,但核型判定符合率较以往增高.此外,ELISA法检测抗CCP抗体、抗AMA及抗dsDNA抗体定量结果差异较大.AMA及ASMA的检测率不高.结论 抗核抗体、抗dsDNA抗体、抗CCP抗体正确率较之前明显升高,三者准确率相似.抗ENA抗体的准确率较以往也略有提高.%Objective To consecutively investigate the quality of auto-antibody testing of the whole country and to improve quality.Methods A nation-wide investigation was carried out and hospitals or departments participating were notified by letter or telephone communication.Autoantibodies tested for quality control survey included anti-nuclear antibody (anti-ANA),anti-double-stranded DNA (anti-dsDNA)antibody,anti-extractable nuclear antigens (anti-ENA) antibody,anti-mitochondria antibody (AMA),anti-smooth muscle antibody (ASMA) and anti-citrulline antibody (anti-CCP).There were 15 samples in total for testing,including 3 control

  9. B Complex Test Control Center (TCC) #4210

    Data.gov (United States)

    Federal Laboratory Consortium — The TCC is a dual control room facility for the B-1 and B-2 Test Positions on the B-Stand. The TCC houses continually-updated, state-of-the-art Data Acquisition and...

  10. Quality charters or quality members? A control theory perspective on team charters and team performance.

    Science.gov (United States)

    Courtright, Stephen H; McCormick, Brian W; Mistry, Sal; Wang, Jiexin

    2017-10-01

    Though prevalent in practice, team charters have only recently received scholarly attention. However, most of this work has been relatively devoid of theory, and consequently, key questions about why and under what conditions team charter quality affects team performance remain unanswered. To address these gaps, we draw on macro organizational control theory to propose that team charter quality serves as a team-level "behavior" control mechanism that builds task cohesion through a structured exercise. We then juxtapose team charter quality with an "input" team control mechanism that influences the emergence of task cohesion more organically: team conscientiousness. Given their redundant effects on task cohesion, we propose that the effects of team charter quality and team conscientiousness on team performance (through task cohesion) are substitutive such that team charter quality primarily impacts team performance for teams that are low (vs. high) on conscientiousness. We test and find support for our hypotheses in a sample of 239 undergraduate self-managing project teams. Our study contributes to the groups and teams literature in the following ways: first, relative to previous studies, we take a more theory-driven approach toward understanding team charters, and in doing so, uncover when and why team charter quality impacts team performance; second, we integrate two normally disparate perspectives on team effectiveness (team development and team selection) to offer a broader perspective on how teams are "built"; and third, we introduce team charter quality as a performance-enhancing mechanism for teams lower on conscientiousness. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

  11. Validation study of the VitaKit A test kit for the determination of vitamin A in fluid milk (2% fat) for routine quality control. Performance Tested Method 061001.

    Science.gov (United States)

    Gupta, Seema; Sui, Xihua; Sikora, Robert; Banasure, Kailash

    2011-01-01

    A validation study of VitaKit A for quantitation of total vitamin A in 2% fluid milk was carried out according to the guidelines provided by AOAC INTERNATIONAL. The VitaKit A was compared, in terms of repeatability and accuracy, with the U.S. Food and Drug Administration-Interstate Milk Shippers HPLC reference method for determination of total vitamin A in fluid milk with 2% fat. The data obtained by the VitaKit A method are in excellent agreement with the data obtained by the HPLC reference method. Further, a low LOD (0.33 international unit/mL) was obtained for the VitaKit A method; the presence of interferents, like cholesterol and vitamin D3, in the milk had minor influence on the quantitation of total vitamin A by the VitaKit A method. The VitaKit A test kit was found to be stable for 1 year from the date of manufacture when stored at 2-8 degrees C. The method requires 2 h processing time, compared to 1-2 days for the HPLC reference method. The results of this validation study clearly demonstrate that the VitaKit A method is reliable, rapid, and accurate for the quantitation of total vitamin A in fluid milk containing 2% milk fat. An independent study by Q Laboratories Inc., Cincinnati, OH, under the validation guidelines of AOAC INTERNATIONAL, confirmed these findings.

  12. Dual control vibration tests of flight hardware

    Science.gov (United States)

    Scharton, Terry D.

    1991-01-01

    A vibration retest of a spacecraft flight instrument, the Mars Observer Camera (MOC), was conducted using extremal dual control to automatically limit the shaker force and notch the shaker acceleration at resonances. This was the first application of extremal dual control with flight hardware at JPL. The retest was successful in that the environment was representative of flight plus some margin, the instrument survived without any structural or performance degradation, and the force limiting worked very well. The test set-up, force limiting procedure, and test results are described herein. It is concluded that dual control should be utilized when there is a concern about overtesting in hard-base-drive tests and the instrumentation for force measurement and control is available. Recommendations for improving the implementation of dual control are provided as a result of this first experience.

  13. Quality Control of Pile Integrity Testing of Cement - flyash - gravel Pile in Construction Process%桩身完整性检测在CFG桩施工过程中的质量控制

    Institute of Scientific and Technical Information of China (English)

    常聚友; 杨丽

    2011-01-01

    Research purposes: From the integrity testing of cement - flyash - gravel pile , it was found that the empty holes, the mud, the soil, mortar between folders, shrinkage diameter and severe maceration (types of honeycomb and separation of sand and stones) appearred in some CFG piles.The study was done on the reasons for these defects.In order to ensure the integrity quality of cement - flyash - gravel pile, the relative construction measures should be taken and the control of the construction quality should be strengthened.Research conclusions: The construction method of "concrete wrapping drill" should be adopted when pouring the concrete of cement - flyash - gravel pile.That is, when the concrete is poured, the pouring surface of concrete should always wrap the drill by 0.5 - 1 metre and synchronously rise with the drill.The concrete slump constant should be controlled to 16 -20 cm, In the anhydrous stratum, the pouring velocity of the concrete should be controlled to 2 -3 m/min.In the water stratum, the pouring velocity of the concrete should be controlled to 1 m/min.In water - rich stratum, the 80 type high- power should be used.In the soft plastic clay stratum (including water layer), the slow pressure construction method should be used for pouring concrete.The pouring of concrete of cement - flyash - gravel pile should be continuous and can not be interrupted.If interrupted, the pile should continue to downward whirl to the depth of 0.5 -1.0 m to drill away the mortar and severe maceration concrete for integrating the new concrete with the concrete at the bottom.%研究目的:本文通过CFG桩完整性检测,对空洞、夹泥、夹土、夹砂浆、缩径、严重离析(蜂窝状、砂石分离状)等施工原因引起的问题进行研究.为确保CFG桩质量完整,应从施工预防着手,制定施工措施,加强施工质量控制.研究结论:CFG桩混凝土灌注时要严格执行"灰包钻"施工法,即灌注混凝土时始终

  14. Sap flow sensors: construction, quality control and comparison.

    Science.gov (United States)

    Davis, Tyler W; Kuo, Chen-Min; Liang, Xu; Yu, Pao-Shan

    2012-01-01

    This work provides a design for two types of sensors, based on the thermal dissipation and heat ratio methods of sap flow calculation, for moderate to large scale deployments for the purpose of monitoring tree transpiration. These designs include a procedure for making these sensors, a quality control method for the final products, and a complete list of components with vendors and pricing information. Both sensor designs were field tested alongside a commercial sap flow sensor to assess their performance and show the importance for quality controlling the sensor outputs. Results show that for roughly 2% of the cost of commercial sensors, self-made sap flow sensors can provide acceptable estimates of the sap flow measurements compared to the commercial sensors.

  15. European wind turbine testing procedure developments. Task 2: Power quality

    DEFF Research Database (Denmark)

    Sørensen, Poul Ejnar; Friis Pedersen, Troels; Gerdes, G.;

    2001-01-01

    The present report describes the work done in the power quality subtask of the European Wind Turbine Testing Procedure Developments project funded by the EU SMT program. The objective of the power quality subtask has been to make recommendations andprovide background for new standards...... for measurement and testing of wind turbine power quality. The focus in the work has been to support the ongoing standardisation work in IEC with a new standard IEC61400-21 for measurement and assessment of powerquality characteristics of grid connected wind turbines. The work has also been based on the power...... quality measuremnet procedure in the Measnet cooperation of European test stations for wind turbines. The first working item of the project has been toverify the state of the art of the measurement procedures by analyses and comparisons of the measurements and data processing software of the participating...

  16. Integrated quality control: implementation and validation of instrument function checks and procedural controls for a cartridge-based point-of-care system for critical care analysis.

    Science.gov (United States)

    D'Orazio, Paul; Mansouri, Sohrab

    2013-03-01

    In this article, the process used to develop and validate an integrated quality-control system for a cartridge-based, point-of-care system for critical care analysis is outlined. Application of risk management principles has resulted in a quality control system using a combination of statistical quality control with onboard reference solutions and failure pattern recognition used to flag common failure modes during the analytical phase of the testing process. A combination of traditional external quality control, integrated quality control to monitor ongoing instrument functionality, operator training, and other laboratory-implemented monitors is most effective in controlling known failure modes during the testing process.

  17. Specifying and testing weld neck flanges for better quality

    Energy Technology Data Exchange (ETDEWEB)

    Weirich, A.B. [Saudi Aramco, Dhahran (Saudi Arabia)

    1996-07-01

    Field failures and persistent defects have impelled users to demand improved reliability in weld neck flanges. This paper explains why and how to specify for better quality. The answers are straightforward: Specify clearly -- Quality begins with improved raw stock, is assured by good manufacturing practices, and is warranted by appropriate quality controls. Be reasonable, specifications must be commercially viable in today`s competitive environment. Inspect the merchandise: Quality cannot be assured without effective enforcement. To think otherwise is unrealistic, regardless how good the procurement specifications may be. Review purchasing policies: When suppliers of quality products are identified, restricted purchases should be instituted. Quicker deliveries and a reliable supply of good quality product are assured as manufacturers maintain upgraded inventories in anticipation of repeat business.

  18. Digital sound: Subjective tests on commentary-quality codecs

    Science.gov (United States)

    Gilchrist, N. H. C.; Oxenham, A. J.

    Subjective tests have been carried out on five commentary-quality audio codecs on behalf of CCIR Task Group 10/2. All codecs operated at a bit rate of 60 kbit/s per mono signal, and were tested in both mono and stereo configurations. Significant differences in performance were found. All codecs introduced some impairment on the most critical program items.

  19. Uniformity microsprinkler irrigation system using statistical quality control

    Directory of Open Access Journals (Sweden)

    Maurício Guy de Andrade

    Full Text Available ABSTRACT: The objective of this study was to evaluate the use of statistical quality control tools in the analysis of the uniformity of a microsprinkler irrigation system. For the analysis of irrigation Christiansen uniformity coefficient (CUC and the distribution uniformity coefficient (DU were statistically analyzed by means of the Shewhart control charts and process capability index (Cp. For the experiment 25 tests were carried out with a single micro sprinkler and subsequently seven different spacing between micro sprinklers were simulated. Control charts contributed to the diagnosis of the treatments to be under control and with satisfactory uniformity outcomes. Increase in process capability index was directly proportional to the average of CUC and DU.

  20. A Total Quality-Control Plan with Right-Sized Statistical Quality-Control.

    Science.gov (United States)

    Westgard, James O

    2017-03-01

    A new Clinical Laboratory Improvement Amendments option for risk-based quality-control (QC) plans became effective in January, 2016. Called an Individualized QC Plan, this option requires the laboratory to perform a risk assessment, develop a QC plan, and implement a QC program to monitor ongoing performance of the QC plan. Difficulties in performing a risk assessment may limit validity of an Individualized QC Plan. A better alternative is to develop a Total QC Plan including a right-sized statistical QC procedure to detect medically important errors. Westgard Sigma Rules provides a simple way to select the right control rules and the right number of control measurements.

  1. Quality performance of laboratory testing in pharmacies: a collaborative evaluation.

    Science.gov (United States)

    Zaninotto, Martina; Miolo, Giorgia; Guiotto, Adriano; Marton, Silvia; Plebani, Mario

    2016-11-01

    The quality performance and the comparability between results of pharmacies point-of-care-testing (POCT) and institutional laboratories have been evaluated. Eight pharmacies participated in the project: a capillary specimen collected by the pharmacist and, simultaneously, a lithium-heparin sample drawn by a physician of laboratory medicine for the pharmacy customers (n=106) were analyzed in the pharmacy and in the laboratory, respectively. Glucose, cholesterol, HDL-cholesterol, triglycerides, creatinine, uric acid, aspartate aminotransferase, alanine aminotransferase, were measured using: Reflotron, n=5; Samsung, n=1; Cardiocheck PA, n=1; Cholestech LDX, n=1 and Cobas 8000. The POCT analytical performance only (phase 2) were evaluated testing, in pharmacies and in the laboratory, the lithium heparin samples from a female drawn fasting daily in a week, and a control sample containing high concentrations of glucose, cholesterol and triglycerides. For all parameters, except triglycerides, the slopes showed a satisfactory correlation. For triglycerides, a median value higher in POCT in comparison to the laboratory (1.627 mmol/L vs. 0.950 mmol/L) has been observed. The agreement in the subjects classification, demonstrates that for glucose, 70% of the subjects show concentrations below the POCT recommended level (5.8-6.1 mmol/L), while 56% are according to the laboratory limit (pharmacies and specific criticisms in the pre- and post-analytical phases.

  2. Mechanical properties of steel rope wires -– quality test assurance

    Directory of Open Access Journals (Sweden)

    Jaroslava Dečmanová

    2010-02-01

    Full Text Available We investigate the mechanical properties of wires of steel ropes by tests in accordance with rule in operation and valid regulation.There are specified values of minimal and maximum capacity or strenghts and values of minimal bendings and torsion in them. Minimalvalues of bendings and torsion are rated wire strenght, diameter and surface treatment dependent. It is suitable to use the calculationof irregularity coefficient of steel wires strenght for quality assessment of steel ropes which put into practice soviet authors Žitkovand Pospechov. Statistical methods make possible to review the quality of steel ropes from the test results of their wires on capacity,bending and torsion. In the paper we evaluate and compare the quality of two steel ropes with triangular strands, we appear fromprotocols about their tests in the accredited testing station of steel ropes of our workstation.

  3. System Quality Management in Software Testing Laboratory that Chooses Accreditation

    Directory of Open Access Journals (Sweden)

    Yanet Brito R.

    2013-12-01

    Full Text Available The evaluation of software products will reach full maturity when executed by the scheme and provides third party certification. For the validity of the certification, the independent laboratory must be accredited for that function, using internationally recognized standards. This brings with it a challenge for the Industrial Laboratory Testing Software (LIPS, responsible for testing the products developed in Cuban Software Industry, define strategies that will permit it to offer services with a high level of quality. Therefore it is necessary to establish a system of quality management according to NC-ISO/IEC 17025: 2006 to continuously improve the operational capacity and technical competence of the laboratory, with a view to future accreditation of tests performed. This article discusses the process defined in the LIPS for the implementation of a Management System of Quality, from the current standards and trends, as a necessary step to opt for the accreditation of the tests performed.

  4. VHDL IMPLEMENTATION OF TEST ACCESS PORT CONTROLLER

    Directory of Open Access Journals (Sweden)

    MANPREET KAUR

    2012-06-01

    Full Text Available In this paper, an implementation of IEEE 1149.7 standard is used for designing Test Access Port (TAP Controller and testing of interconnects is done using boundary scan. By c-JTAG the pin count gets reduced which increases the performance and simplifies the connection between devices. TAP Controller is a synchronous Moore type finite state machine that is changed when the TMS and TCK signals of the test access port gets change. This controls the sequence operation of the circuitry conveyed by JTAG and c-JTAG. JTAGmainly used four pins with TAP and fifth pin is for optional use in Boundary scan. But c-JTAG uses only two pins with TAP. In this approach TDI and TDO gets multiplexed by using class T4 and T5 of c-JTAG. Various instructions are used for testing interconnects using IEEE 1149.7 standard (std.

  5. Chapter 5: Quality assurance/quality control in stormwater sampling

    Science.gov (United States)

    Sampling the quality of stormwater presents unique challenges because stormwater flow is relatively short-lived with drastic variability. Furthermore, storm events often occur with little advance warning, outside conventional work hours, and under adverse weather conditions. Therefore, most stormwat...

  6. Ground test for vibration control demonstrator

    Science.gov (United States)

    Meyer, C.; Prodigue, J.; Broux, G.; Cantinaud, O.; Poussot-Vassal, C.

    2016-09-01

    In the objective of maximizing comfort in Falcon jets, Dassault Aviation is developing an innovative vibration control technology. Vibrations of the structure are measured at several locations and sent to a dedicated high performance vibration control computer. Control laws are implemented in this computer to analyse the vibrations in real time, and then elaborate orders sent to the existing control surfaces to counteract vibrations. After detailing the technology principles, this paper focuses on the vibration control ground demonstration that was performed by Dassault Aviation in May 2015 on Falcon 7X business jet. The goal of this test was to attenuate vibrations resulting from fixed forced excitation delivered by shakers. The ground test demonstrated the capability to implement an efficient closed-loop vibration control with a significant vibration level reduction and validated the vibration control law design methodology. This successful ground test was a prerequisite before the flight test demonstration that is now being prepared. This study has been partly supported by the JTI CleanSky SFWA-ITD.

  7. Avaliação de recomendações normativas sobre o uso de ensaios no controle de qualidade de fabricação de geossintéticos Evaluation of standard recommendations on the use of tests for manufacturing quality control of geosynthetics

    Directory of Open Access Journals (Sweden)

    Carina M. L. Costa

    2008-06-01

    Full Text Available A utilização de materiais poliméricos designados por geossintéticos tem aumentando significativamente nos últimos anos na Engenharia Civil. Para desempenhar adequadamente a função para a qual foram projetados, os geossintéticos devem ser submetidos a um rigoroso processo de controle de qualidade durante a fabricação. Discussões sobre a freqüência e os principais tipos de ensaios de laboratório utilizados nesse processo de controle para dois tipos de geossintéticos, os geotêxteis e as geomembranas, os materiais mais utilizados da famíla dos geossintéticos, são abordados no presente trabalho. As análises efetuadas com base em normas disponíveis no Brasil, nos EUA e na Europa mostram que no cenário nacional não há recomendações normativas sobre o controle de qualidade para a maioria das aplicações de geotêxteis e geomembranas, sendo o assunto pouco discutido na literatura técnica. No cenário internacional, as normas Européias se destacam como o conjunto de práticas mais completo para ensaios de controle de qualidade de fabricação, considerando os diversos tipos de aplicação dos geossintéticos na Engenharia Civil.The use of polymeric materials known as geosynthetics in Civil Engineering applications has increased significantly in the last few years. In order to perform adequately, geosynthetics need to be manufactured according to rigorous quality control procedures. This paper addresses the frequency and the main types of laboratory tests used for quality control of geotextiles and geomembranes, which are the most largely used materials within the geosynthetic family. Analyses based on technical standards from Brazil, USA and Europe show the need of quality control recommendations for a large number of applications of geotextiles and geomembranes in Brazil. Also, very limited information on this topic is available in Brazilian literature. Conversely, European standards on the subject take into consideration a

  8. 14 CFR 21.147 - Changes in quality control system.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Changes in quality control system. 21.147 Section 21.147 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION... quality control system. After the issue of a production certificate, each change to the quality...

  9. Methods for the Quality Control of Inactivated Poliovirus Vaccines.

    Science.gov (United States)

    Wilton, Thomas

    2016-01-01

    Inactivated poliovirus vaccine (IPV) plays an instrumental role in the Global Poliovirus Eradication Initiative (GPEI). The quality of IPV is controlled by assessment of the potency of vaccine batches. The potency of IPV can be assessed by both in vivo and in vitro methods. In vitro potency assessment is based upon the assessment of the quantity of the D-Antigen (D-Ag) units in an IPV. The D-Ag unit is used as a measure of potency as it is largely expressed on native infectious virions and is the protective immunogen. The most commonly used in vitro test is the indirect ELISA which is used to ensure consistency throughout production.A range of in vivo assays have been developed in monkeys, chicks, guinea pigs, mice, and rats to assess the potency of IPV. All are based on assessment of the neutralizing antibody titer within the sera of the respective animal model. The rat potency test has become the favored in vivo potency test as it shows minimal variation between laboratories and the antibody patterns of rats and humans are similar. With the development of transgenic mice expressing the human poliovirus receptor, immunization-challenge tests have been developed to assess the potency of IPVs. This chapter describes in detail the methodology of these three laboratory tests to assess the quality of IPVs.

  10. US quality control in Italy: present and future

    Science.gov (United States)

    Balbis, S.; Musacchio, C.; Guiot, C.; Spagnolo, R.

    2011-02-01

    US diagnostic equipments are widely diffused in Italy but, in spite of recommendations (e.g. ISPESL-Ministry of Health (1999) and SIRM (Società Italiana di Radiologia Medica, 2004), US quality controls are restricted to only a few public sanitary structure and a national (or even regional) quality assurance program for testing the performances of the US equipments is still missing. A joint Research Centre among the three Piedmontese Universities and INRIM, partially funded by Regione Piemonte, has been established in 2009 as Reference Centre for Medical Ultrasounds (CRUM). In addition to research, development and training tasks, the Centre aims at the local diffusion of the quality assurance in clinical US equipments. According to data from the Ministry of Health (2006), around 7 % of the Italian US diagnostic equipments (946 over 13526) are located in Piedmont: mostly (75.6%) in public hospitals, 9.3 % in conventionated hospitals, 4.3% in public and 10.8% in private territorial structures. The goal is the provision of a regional database, which progressively includes data related to acceptance test, status and QC tests and maintenance, in order to drive equipment turnover and carefully monitoring the overall equipment efficiency. Moreover, facilities are available at CRUM for monitoring both beam geometry and acoustic power and performing quantitative assessment of the delivered energy intensity.

  11. Standards for measurements and testing of wind turbine power quality

    Energy Technology Data Exchange (ETDEWEB)

    Soerensen, P. [Risoe National Lab., Roskilde (Denmark); Gerdes, G.; Klosse, R.; Santjer, F. [DEWI, Wilhelmshaven (Germany); Robertson, N.; Davy, W. [NEL, Glasgow (United Kingdom); Koulouvari, M.; Morfiadakis, E. [CRES, Pikermi (Greece); Larsson, Aa. [Chalmers Univ. of Technology, Goeteborg (Sweden)

    1999-03-01

    The present paper describes the work done in power quality sub-task of the project `European Wind Turbine Testing Procedure Developments` funded by the EU SMT program. The objective of the power quality sub-task has been to make analyses and new recommendation(s) for the standardisation of measurement and verification of wind turbine power quality. The work has been organised in three major activities. The first activity has been to propose measurement procedures and to verify existing and new measurement procedures. This activity has also involved a comparison of the measurements and data processing of the participating partners. The second activity has been to investigate the influence of terrain, grid properties and wind farm summation on the power quality of wind turbines with constant rotor speed. The third activity has been to investigate the influence of terrain, grid properties and wind farm summation on the power quality of wind turbines with variable rotor speed. (au)

  12. Simulation-based Testing of Control Software

    Energy Technology Data Exchange (ETDEWEB)

    Ozmen, Ozgur [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Nutaro, James J. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Sanyal, Jibonananda [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Olama, Mohammed M. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)

    2017-02-10

    It is impossible to adequately test complex software by examining its operation in a physical prototype of the system monitored. Adequate test coverage can require millions of test cases, and the cost of equipment prototypes combined with the real-time constraints of testing with them makes it infeasible to sample more than a small number of these tests. Model based testing seeks to avoid this problem by allowing for large numbers of relatively inexpensive virtual prototypes that operate in simulation time at a speed limited only by the available computing resources. In this report, we describe how a computer system emulator can be used as part of a model based testing environment; specifically, we show that a complete software stack including operating system and application software - can be deployed within a simulated environment, and that these simulations can proceed as fast as possible. To illustrate this approach to model based testing, we describe how it is being used to test several building control systems that act to coordinate air conditioning loads for the purpose of reducing peak demand. These tests involve the use of ADEVS (A Discrete Event System Simulator) and QEMU (Quick Emulator) to host the operational software within the simulation, and a building model developed with the MODELICA programming language using Buildings Library and packaged as an FMU (Functional Mock-up Unit) that serves as the virtual test environment.

  13. Piezoelectric energy harvesting computer controlled test bench.

    Science.gov (United States)

    Vázquez-Rodriguez, M; Jiménez, F J; de Frutos, J; Alonso, D

    2016-09-01

    In this paper a new computer controlled (C.C.) laboratory test bench is presented. The patented test bench is made up of a C.C. road traffic simulator, C.C. electronic hardware involved in automating measurements, and test bench control software interface programmed in LabVIEW™. Our research is focused on characterizing electronic energy harvesting piezoelectric-based elements in road traffic environments to extract (or "harvest") maximum power. In mechanical to electrical energy conversion, mechanical impacts or vibrational behavior are commonly used, and several major problems need to be solved to perform optimal harvesting systems including, but no limited to, primary energy source modeling, energy conversion, and energy storage. It is described a novel C.C. test bench that obtains, in an accurate and automatized process, a generalized linear equivalent electrical model of piezoelectric elements and piezoelectric based energy store harvesting circuits in order to scale energy generation with multiple devices integrated in different topologies.

  14. Piezoelectric energy harvesting computer controlled test bench

    Science.gov (United States)

    Vázquez-Rodriguez, M.; Jiménez, F. J.; de Frutos, J.; Alonso, D.

    2016-09-01

    In this paper a new computer controlled (C.C.) laboratory test bench is presented. The patented test bench is made up of a C.C. road traffic simulator, C.C. electronic hardware involved in automating measurements, and test bench control software interface programmed in LabVIEW™. Our research is focused on characterizing electronic energy harvesting piezoelectric-based elements in road traffic environments to extract (or "harvest") maximum power. In mechanical to electrical energy conversion, mechanical impacts or vibrational behavior are commonly used, and several major problems need to be solved to perform optimal harvesting systems including, but no limited to, primary energy source modeling, energy conversion, and energy storage. It is described a novel C.C. test bench that obtains, in an accurate and automatized process, a generalized linear equivalent electrical model of piezoelectric elements and piezoelectric based energy store harvesting circuits in order to scale energy generation with multiple devices integrated in different topologies.

  15. CR mammography: Design and implementation of a quality control program

    Energy Technology Data Exchange (ETDEWEB)

    Moreno-Ramirez, A.; Brandan, M. E.; Villasenor-Navarro, Y.; Galvan, H. A.; Ruiz-Trejo, C. [Instituto de Fisica, Universidad Nacional Autonoma de Mexico, DF 04510 (Mexico); Departamento de Radiodiagnostico, Instituto Nacional de Cancerologia, DF 14080 (Mexico); Instituto de Fisica, Universidad Nacional Autonoma de Mexico, DF 04510 (Mexico)

    2012-10-23

    Despite the recent acquisition of significant quantities of computed radiography CR equipment for mammography, Mexican regulations do not specify the performance requirements for digital systems such as those of CR type. The design of a quality control program QCP specific for CR mammography systems was thus considered relevant. International protocols were taken as reference to define tests, procedures and acceptance criteria. The designed QCP was applied in three CR mammography facilities. Important deficiencies in spatial resolution, noise, image receptor homogeneity, artifacts and breast thickness compensation were detected.

  16. LHC Magnet Test Benches Controls Renovation

    CERN Document Server

    Andreassen, O O; Page, S; Raimondo, A; Rijllart, A; Zorin, E

    2011-01-01

    The LHC magnet test benches controls were designed in 1996. They were based on VME data acquisition systems, Siemens PLCs control and interlocks systems. After a review of renovation of superconducting laboratories at CERN in 2009, it was decided to replace the VME systems with a PXI based systems and the obsolete Sun/Solaris workstations with Linux PC’s. This paper covers the requirements for the new system and shares the experience of the upgrade of the magnet test benches to these new platforms.

  17. MITOCHONDRIA QUALITY CONTROL AND MUSCLE MASS MAINTENANCE

    Directory of Open Access Journals (Sweden)

    Vanina eRomanello

    2016-01-01

    Full Text Available Loss of muscle mass and force occurs in many diseases such as disuse/inactivity, diabetes, cancer, renal and cardiac failure and in aging-sarcopenia. In these catabolic conditions the mitochondrial content, morphology and function are greatly affected. The changes of mitochondrial network influence the production of reactive oxygen species (ROS that play an important role in muscle function. Moreover, dysfunctional mitochondria trigger catabolic signaling pathways which feed-forward to the nucleus to promote the activation of muscle atrophy. Exercise, on the other hand, improves mitochondrial function by activating mitochondrial biogenesis and mitophagy, possibly playing an important part in the beneficial effects of physical activity in several diseases. Optimised mitochondrial function is strictly maintained by the coordinated activation of different mitochondrial quality control pathways. In this review we outline the current knowledge linking mitochondria-dependent signaling pathways to muscle homeostasis in aging and disease and the resulting implications for the development of novel therapeutic approaches to prevent muscle loss.

  18. Managing Quality in Higher Education Systems via Minimal Quality Requirements: Signaling and Control.

    Science.gov (United States)

    Mizrahi, Shlomo; Mehrez, Abraham

    2002-01-01

    Discusses two versions of a signaling game to set minimal quality requirements for higher education applicants in Israel: one assumes low sensitivity to quality, the other high sensitivity. Concludes that indirect government influence on quality variations in applicant pool is more effective in controlling institutional quality then direct…

  19. Analytical approaches to quality assurance and quality control in rangeland monitoring data

    Science.gov (United States)

    Producing quality data to support land management decisions is the goal of every rangeland monitoring program. However, the results of quality assurance (QA) and quality control (QC) efforts to improve data quality are rarely reported. The purpose of QA and QC is to prevent and describe non-sampling...

  20. Advances in quality control for dioxins monitoring and evaluation of measurement uncertainty from quality control data.

    Science.gov (United States)

    Eppe, Gauthier; De Pauw, Edwin

    2009-08-01

    This paper describes an application of multivariate and multilevel quality control charts with the aim of improving the internal quality control (IQC) procedures for the monitoring of dioxins and dioxin-like PCBs analysis in food. Dioxin analysts have to use the toxic equivalent concept (TEQ) to assess the toxicity potential of a mixture of dioxin-like compounds. The TEQ approach requires quantifying individually 29 dioxin-like compounds. Monitoring the congeners separately on univariate QC charts is misleading owing to the increase of false alarm rate. We propose to subdivide the TEQ value into 3 sub-groups and to control simultaneously the 3 variables in a T(2) chart. When a T(2) exceeds the upper control limit, it acts as a warning to trigger additional investigations on individual congeners. We discuss the minimum number of runs required to reliably estimate the QC chart parameters and we suggest using data from multilevel QC charts to properly characterize the standard deviations and the correlation coefficients. Moreover, the univariate QC chart can be sensitised to detect systematic errors by using exponentially weighted moving average (EWMA) technique. The EWMA chart provides an additional guidance on setting appropriate criteria to control the method bias and to support trend analysis. Finally, we present an estimate of measurement uncertainty by computing the accuracy profile in a retrospective way with the QC data generated and we discuss assessment of compliance with regulatory maximum levels.

  1. Quality assurance standards for purchasing and inventory control.

    Science.gov (United States)

    Soares, D P

    1985-03-01

    A process is described for quality assurance in pharmaceutical purchasing and inventory control. A quality assurance program should ensure that quality drugs are purchased at the lowest price, drug products are available when needed, the system is managed efficiently, internal controls are provided, drug products are stored under appropriate conditions, and laws, regulations, accreditation standards, and procedures are followed. To meet these objectives, product quality, vendor performance, the department's system of internal controls, purchasing data, and storage conditions should be monitored. A checklist for evaluating purchasing and inventory practices and a sample audit form listing quality assurance criteria, standards, procedures, and recommended actions are provided. A quality assurance program for pharmaceutical purchasing and inventory control should define institution-specific criteria and standards and use these standards for continual evaluation of all aspects of the purchasing and inventory control system. Documentation of quality assurance activities should be provided for use by the purchasing department, hospital administration, and regulatory bodies.

  2. Scale Control and Quality Management of Printed Image Parameters

    Science.gov (United States)

    Novoselskaya, O. A.; Kolesnikov, V. L.; Solov'eva, T. V.; Nagornova, I. V.; Babluyk, E. B.; Trapeznikova, O. V.

    2017-06-01

    The article provides a comparison of the main valuation techniques for a regulated parameter of printability of the offset paper by current standards GOST 24356 and ISO 3783: 2006. The results of development and implementation of a complex test scale for management and control the quality of printed production are represented. The estimation scale is introduced. It includes normalized parameters of print optical density, print uniformity, picking out speed, the value of dot gain, print contrast with the added criteria of minimizing microtexts, a paper slip, resolution threshold and effusing ability of paper surface. The results of analysis allow directionally form surface properties of the substrate to facilitate achieving the required quality of the printed image parameters, i. e. optical density of a print at a predetermined level not less than 1.3, the print uniformity with minimal deviation of dot gain about the order of 10 per cents.

  3. Flight Test of an Intelligent Flight-Control System

    Science.gov (United States)

    Davidson, Ron; Bosworth, John T.; Jacobson, Steven R.; Thomson, Michael Pl; Jorgensen, Charles C.

    2003-01-01

    inputs with the outputs provided to instrumentation only. The IFCS was not used to control the airplane. In another stage of the flight test, the Phase I pre-trained neural network was integrated into a Phase III version of the flight control system. The Phase I pretrained neural network provided realtime stability and control derivatives to a Phase III controller that was based on a stochastic optimal feedforward and feedback technique (SOFFT). This combined Phase I/III system was operated together with the research flight-control system (RFCS) of the F-15 ACTIVE during the flight test. The RFCS enables the pilot to switch quickly from the experimental- research flight mode back to the safe conventional mode. These initial IFCS ACP flight tests were completed in April 1999. The Phase I/III flight test milestone was to demonstrate, across a range of subsonic and supersonic flight conditions, that the pre-trained neural network could be used to supply real-time aerodynamic stability and control derivatives to the closed-loop optimal SOFFT flight controller. Additional objectives attained in the flight test included (1) flight qualification of a neural-network-based control system; (2) the use of a combined neural-network/closed-loop optimal flight-control system to obtain level-one handling qualities; and (3) demonstration, through variation of control gains, that different handling qualities can be achieved by setting new target parameters. In addition, data for the Phase-II (on-line-learning) neural network were collected, during the use of stacked-frequency- sweep excitation, for post-flight analysis. Initial analysis of these data showed the potential for future flight tests that will incorporate the real-time identification and on-line learning aspects of the IFCS.

  4. Spaceport Command and Control System Automation Testing

    Science.gov (United States)

    Plano, Tom

    2017-01-01

    The goal of automated testing is to create and maintain a cohesive infrastructure of robust tests that could be run independently on a software package in its entirety. To that end, the Spaceport Command and Control System (SCCS) project at the National Aeronautics and Space Administration's (NASA) Kennedy Space Center (KSC) has brought in a large group of interns to work side-by-side with full time employees to do just this work. Thus, our job is to implement the tests that will put SCCS through its paces.

  5. Improved methodology for generating controlled test atmospheres.

    Science.gov (United States)

    Miller, R R; Letts, R L; Potts, W J; McKenna, M J

    1980-11-01

    Improved methodology has been developed for generating controlled test atmospheres. Vaporization of volatile liquids is accomplished in a 28 mm (O.D.) glass J-tube in conjunction with a compressed air flameless heat torch, a pressure-sensitive switch, and a positive displacement piston pump. The vaporization system has been very reliable with a variety of test materials in studies ranging from a few days to several months. The J-tube vaporization assembly minimizes the possibility of thermal decomposition of the test material and affords a better margin of safety when vaporizing potentially explosive materials.

  6. Proposed quality control protocol of a dual energy bone densitometer from Spanish protocol for quality control of radiology; Propuesta de protocolo de control de calidad de un densitometro oseo de energia dual a partir del protocolo espanol de control de calidad de radiodiagnostico

    Energy Technology Data Exchange (ETDEWEB)

    Saez, F.; Benito, M. A.; Collado, P.; Saez, M.

    2011-07-01

    In this paper we propose additional testing to complete the tests by the Spanish Protocol for Quality Control of Diagnostic Radiology, taking into account the particular characteristics of these units, and including these tests in the estimation of patient dose dose assessment area. There is also the possibility to independently verify the quality control tests that are done automatically.

  7. Quality control with R an ISO standards approach

    CERN Document Server

    Cano, Emilio L; Prieto Corcoba, Mariano

    2015-01-01

    Presenting a practitioner's guide to capabilities and best practices of quality control systems using the R programming language, this volume emphasizes accessibility and ease-of-use through detailed explanations of R code as well as standard statistical methodologies. In the interest of reaching the widest possible audience of quality-control professionals and statisticians, examples throughout are structured to simplify complex equations and data structures, and to demonstrate their applications to quality control processes, such as ISO standards. The volume balances its treatment of key aspects of quality control, statistics, and programming in R, making the text accessible to beginners and expert quality control professionals alike. Several appendices serve as useful references for ISO standards and common tasks performed while applying quality control with R.

  8. High Quality Test Pattern Generation and Boolean Satisfiability

    CERN Document Server

    Eggersglüß, Stephan

    2012-01-01

    This book provides an overview of automatic test pattern generation (ATPG) and introduces novel techniques to complement classical ATPG, based on Boolean Satisfiability (SAT).  A fast and highly fault efficient SAT-based ATPG framework is presented which is also able to generate high-quality delay tests such as robust path delay tests, as well as tests with long propagation paths to detect small delay defects. The aim of the techniques and methodologies presented in this book is to improve SAT-based ATPG, in order to make it applicable in industrial practice. Readers will learn to improve the performance and robustness of the overall test generation process, so that the ATPG algorithm reliably will generate test patterns for most targeted faults in acceptable run time to meet the high fault coverage demands of industry. The techniques and improvements presented in this book provide the following advantages: Provides a comprehensive introduction to test generation and Boolean Satisfiability (SAT); Describes a...

  9. Handling Qualities of Model Reference Adaptive Controllers with Varying Complexity for Pitch-Roll Coupled Failures

    Science.gov (United States)

    Schaefer, Jacob; Hanson, Curt; Johnson, Marcus A.; Nguyen, Nhan

    2011-01-01

    Three model reference adaptive controllers (MRAC) with varying levels of complexity were evaluated on a high performance jet aircraft and compared along with a baseline nonlinear dynamic inversion controller. The handling qualities and performance of the controllers were examined during failure conditions that induce coupling between the pitch and roll axes. Results from flight tests showed with a roll to pitch input coupling failure, the handling qualities went from Level 2 with the baseline controller to Level 1 with the most complex MRAC tested. A failure scenario with the left stabilator frozen also showed improvement with the MRAC. Improvement in performance and handling qualities was generally seen as complexity was incrementally added; however, added complexity usually corresponds to increased verification and validation effort required for certification. The tradeoff between complexity and performance is thus important to a controls system designer when implementing an adaptive controller on an aircraft. This paper investigates this relation through flight testing of several controllers of vary complexity.

  10. 42 CFR 84.256 - Quality control requirements.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Quality control requirements. 84.256 Section 84.256... § 84.256 Quality control requirements. (a) In addition to the construction and performance requirements specified in §§ 84.251, 84.252, 84.253, 84.254, and 84.255, the quality control requirements in...

  11. Quality control in bio-monitoring networks, Spanish Aerobiology Network.

    Science.gov (United States)

    Oteros, Jose; Galán, Carmen; Alcázar, Purificación; Domínguez-Vilches, Eugenio

    2013-01-15

    Several of the airborne biological particles, such as pollen grains and fungal spores, are known to generate human health problems including allergies and infections. A number of aerobiologists have focused their research on these airborne particles. The Spanish Aerobiology Network (REA) was set up in 1992, and since then dozens of research groups have worked on a range of related topics, including the standardization of study methods and the quality control of data generated by this network. In 2010, the REA started work on an inter-laboratory survey for proficiency testing purposes. The main goal of the study reported in the present paper was to determine the performance of technicians in the REA network using an analytical method that could be implemented by other bio-monitoring networks worldwide. The results recorded by each technician were compared with the scores obtained for a bounded mean of all results. The performance of each technician was expressed in terms of the relative error made in counting each of several pollen types. The method developed and implemented here proved appropriate for proficiency testing in interlaboratory studies involving bio-monitoring networks, and enabled the source of data quality problems to be pinpointed. The test revealed a variation coefficient of 10%. The relative error was significant for 3.5% of observations. In overall terms, the REA staff performed well, in accordance with the REA Management and Quality Manual. These findings serve to guarantee the quality of the data obtained, which can reliably be used for research purposes and published in the media in order to help prevent pollen-related health problems.

  12. Does quantity generate quality? Testing the fundamental principle of brainstorming.

    Science.gov (United States)

    Muñoz Adánez, Alfredo

    2005-11-01

    The purpose of this work is to test the chief principle of brainstorming, formulated as "quantity generates quality." The study is included within a broad program whose goal is to detect the strong and weak points of creative techniques. In a sample of 69 groups, containing between 3 and 8 members, the concurrence of two commonly accepted criteria was established as a quality rule: originality and utility or value. The results fully support the quantity-quality relation (r = .893): the more ideas produced to solve a problem, the better quality of the ideas. The importance of this finding, which supports Osborn's theory, is discussed, and the use of brainstorming is recommended to solve the many open problems faced by our society.

  13. MEASURABILITY OF ORAL SPEECH SAMPLE AS A TEST QUALITY

    Directory of Open Access Journals (Sweden)

    Olena Petrashchuk

    2011-03-01

    Full Text Available Abstract. The article deals with the problem of measurability of oral speech sample as a test quality.Provision of this quality is required for reliability of assessment speaking skills. The main focus is on specificnature of speaking skill including its mental, communication and social aspects. Assessment of speakingskills is analyzed through prism of descriptors of rating scales proposed in ICAO documents. Method of oralproficiency interview is applied to obtain an oral speech sample measurable against the scales. Themeasurability of oral speech sample is considered as a Speaking Test quality alongside with other testqualities such as validity and reliability.Keywords: aviation english language proficiency, ICAO rating scale, measurability of oral speechperformance, oral speech sample, speaking skill.

  14. Antimisting kerosene: Base fuel effects, blending and quality control techniques

    Science.gov (United States)

    Yavrouian, A. H.; Ernest, J.; Sarohia, V.

    1984-01-01

    The problems associated with blending of the AMK additive with Jet A, and the base fuel effects on AMK properties are addressed. The results from the evaluation of some of the quality control techniques for AMK are presented. The principal conclusions of this investigation are: significant compositional differences for base fuel (Jet A) within the ASTM specification DI655; higher aromatic content of the base fuel was found to be beneficial for the polymer dissolution at ambient (20 C) temperature; using static mixer technology, the antimisting additive (FM-9) is in-line blended with Jet A, producing AMK which has adequate fire-protection properties 15 to 20 minutes after blending; degradability of freshly blended and equilibrated AMK indicated that maximum degradability is reached after adequate fire protection is obtained; the results of AMK degradability as measured by filter ratio, confirmed previous RAE data that power requirements to decade freshly blended AMK are significantly higher than equilibrated AMK; blending of the additive by using FM-9 concentrate in Jet A produces equilibrated AMK almost instantly; nephelometry offers a simple continuous monitoring capability and is used as a real time quality control device for AMK; and trajectory (jet thurst) and pressure drop tests are useful laboratory techniques for evaluating AMK quality.

  15. QUALITY CONTROL FOR EFFECTIVE BASIC EDUCATION IN

    African Journals Online (AJOL)

    Ghana 's educational system yet the system of monitoring schools is governed by an “evolving” policy. ... that schools are well supervised and that the quality of what ... quality comes from having the best equipment, the best .... performance in the classroom and their career ... the number of teachers employed and the size of.

  16. Tests for evaluating the physiological quality of pitaya seeds

    Directory of Open Access Journals (Sweden)

    Thiago Alberto Ortiz

    2015-12-01

    Full Text Available Germination test is used to assess the physiological quality of seeds; however, since it is carried out under ideal conditions, this test has not been shown sufficient for this purpose. Instead, it is possible to use vigor tests, although the lack of standardized methodologies has reduced their applicability and reproducibility. Thus, this study aimed to develop methodologies for conducting tests of germination, accelerated aging, and electrical conductivity for the evaluation of the physiological quality of pitaya seeds. For this purpose, seeds from ripe Hylocereus undatus fruits were used. A completely randomized experimental design was used with four replications. The physiological quality of the seeds was assessed using germination, accelerated aging, and electrical conductivity tests, and the speed of germination index (SGI and mean germination time (MGT were determined for both the germination test and accelerated aging test. For the statistical analysis, we performed regression model adjustments and calculated the Pearson correlation coefficient (p < 0.05. The germination test for H. undatus seeds can be performed at 25 °C, with the aim of reaching the highest SGI and lowest MGT values. The accelerated aging test can be conducted at 43 °C for 48 h, because combining these factors favors the expression of seed vigor, allowing seeds to achieve the maximum SGI and minimum MGT, while reducing the time of the assay. The electrical conductivity test can be performed using 25 seeds at a temperature of 30 °C and a water volume of 10 mL, since under these conditions there is less interference from external factors on the leachate content of the solution.

  17. Endoplasmic reticulum quality control and apoptosis.

    Science.gov (United States)

    Groenendyk, Jody; Michalak, Marek

    2005-01-01

    The ER is one of the most important folding compartments within the cell, as well as an intracellular Ca(2+) storage organelle and it contains a number of Ca(2+) regulated molecular chaperones responsible for the proper folding of glycosylated as well as non-glycosylated proteins. The luminal environment of the ER contains Ca(2+) which is involved in regulating chaperones such as calnexin and calreticulin, as well as apoptotic proteins caspase-12 and Bap31, which may play an important role in determining cellular sensitivity to ER stress and apoptosis. The ER quality control system consists of several molecular chaperones, including calnexin, that assist in properly folding proteins and transporting them through the ER as well as sensing misfolded proteins, attempting to refold them and if this is not possible, targeting them for degradation. Accumulation of misfolded protein in the ER leads to activation of genes responsible for the expression of ER chaperones. The UPR mechanism involves transcriptional activation of chaperones by the membrane-localized transcription factor ATF6, in conjunction with the ER membrane kinase IRE1, as well as translational repression of protein synthesis by another ER membrane kinase PERK. When accumulation of misfolded protein becomes toxic, apoptosis is triggered, potentially with IRE1 involved in signaling via caspase-12. Both the extrinsic and intrinsic apoptotic pathways appear to culminate in the activation of caspases and this results in the recruitment of mitochondria in an essential amplifying manner. Bap31 may direct pro-apoptotic crosstalk between the ER and the mitochondria via Ca(2+) in conjunction with caspase-12 and calnexin. Accordingly, ER stress and the resultant Ca(2+) release must be very carefully regulated because of their effects in virtually all areas of cell function.

  18. General Quality Control (QC) Guidelines for SAM Methods

    Science.gov (United States)

    Learn more about quality control guidelines and recommendations for the analysis of samples using the methods listed in EPA's Selected Analytical Methods for Environmental Remediation and Recovery (SAM).

  19. Testing the Children Quantity-Quality Trade-Off in India

    OpenAIRE

    Kumar, Santosh; Kugler, Adriana

    2011-01-01

    Using data from a representative sample from India, we test the empirical validity of Quantity-Quality tarde-off model of Becker and Lewis (1973). To address the endogeneity arising from the joint determination of quantity and quality of children by parents, we instrument the family size by sex of the first child. We find a negative relationship between family size and children's educational attainment, even after controlling for parent's characteristics and birth order of children. ...

  20. Assessment Sleep Quality and its Relationship with Test Anxiety among High School Students in Qom- Iran

    Directory of Open Access Journals (Sweden)

    Saman barmeh ziyar

    2016-10-01

    Full Text Available Background Test anxiety is a special case of a general anxiety which is of particular importance in students, because students will be the future of the country and the society activists. On the other hand, sleep quality and sleep disorders, have correlation with ailments, poor performance, decreased quality of life and increase of associated costs; This study aimed to determine the quality of sleep and its relationship with test anxiety among students in Qom city, Iran. Materials and Methods This study was a cross-sectional study, which was performed among 250 students who were going to pass the exam preparation classes. In order to collect data Pittsburgh Sleep Quality Index (PSQI questionnaires and Test Anxiety Inventory (TAI questionnaire were used. Data were analyzed using SPSS-16 with descriptive statistics and statistical methods, independent t-test, ANOVA and Pearson correlation coefficient. Results In this study, 50% of participants were boys (n=125 and 50 percent were girls (n=125. 81.4% of subjects had poor sleep quality and 69.6% had average to high score for test anxiety. Based on the results of anxiety test and sleep quality index there was a significant correlation between anxiety and sleep quality with gender (P=0.003, r=0.447. Conclusion School children had poor sleep quality and high test anxiety, and due to their direct and significant correlation, attention to this category of students, especially for girls, is important. Therefore, anxiety and promoting sleep quality control programs are recommended in this group.

  1. [Official experimental testing of biomedical products. Regulatory frame and importance of for quality, safety and efficacy].

    Science.gov (United States)

    Vieths, S; Seitz, R

    2014-10-01

    The official experimental testing of biomedicinal products provides a very significant contribution to ensuring quality, safety and efficacy of these indispensable medicines. Already in the prelicensing phase or to elucidate clusters of increased adverse effects, official medicinal control laboratories are committed to perform experimental testing. The official batch release can be seen as external quality control of the manufacturer's release testing. For proficient performance in these tasks, scientific research is required, in particular on the development and refinement of test methods, and considering the continuous development of innovative biomedicinal products. This article is aimed at introducing the present thematic issue and in particular the regulatory basis of experimental product testing, and illustrates by means of several examples its great importance for the sake of the patients.

  2. The effect of test specifications review on improving the quality of a test

    Directory of Open Access Journals (Sweden)

    Hamed Zandi

    2014-01-01

    Full Text Available Reviewing the test specifications to improve the quality of language tests may be a routine process in professional testing systems. However, there is a paucity of research about the effect of specifications review on improving the quality of small-scale tests. The purpose of the present study was twofold: how specifications review could help improve the validity of a test in the context of assessment for learning (AFL and to what extent qualitative review of items can identify poor ones. To this end, a group of trained test specifications reviewers (No = 7 provided feedback on the specifications of a test and the quality of the items. Analysis of feedback showed that pedagogical concerns naturally emerged during the specifications review and led to concrete suggestions on how the specifications could be revised so that the resulting test could become more useful in a classroom context. Moreover, the test items were administered to a group of (No = 40 test-takers and a set of quantitative item analyses was carried out. Comparison of the results of qualitative judgment of reviewers with the quantitative analyses showed about 38 % of the items suggested for revision by the reviewers were also identified as poor by the classical test theory (CTT analysis. The findings highlight the potential of specifications review as part of the a priori validation of tests in small-scale assessments where conducting statistical analysis is not usually feasible.

  3. Testing theOdour Quality of Non-Metallic Materials

    Directory of Open Access Journals (Sweden)

    AVIJIT SINGH GANGWAR

    2014-10-01

    Full Text Available This report has been compiled on the completion of 3 week summer training at ICAT. It discusses about a very necessary and least popular part of the Automotive Industry i.e. Testing and Certification. It discusses about one of the government notified Testing body ICAT which is one of just 6 such organisations in India.This report deals with the odour quality testing of non-metallic materials that are used for automobile compartment and parts associated with the compartment.

  4. Quality Control Assessment of Radiology Devices in Kerman Province, Iran

    Directory of Open Access Journals (Sweden)

    Zahra Jomehzadeh

    2016-03-01

    Full Text Available Introduction Application of quality control (QC programs at diagnostic radiology departments is of great significance for optimization of image quality and reduction of patient dose. The main objective of this study was to perform QC tests on stationary radiographic X-ray machines, installed in 14 hospitals of Kerman province, Iran. Materials and Methods In this cross-sectional study, QC tests were performed on 28 conventional radiographic X-ray units in Kerman governmental hospitals, based on the protocols and criteria recommended by the Atomic Energy Organization of Iran (AEOI, using a calibrated Gammex QC kit. Each section of the QC kit incorporated different models. Results Based on the findings, kVp accuracy, kVp reproducibility, timer accuracy, timer reproducibility, exposure reproducibility, mA/timer linearity, and half-value layer were not within the acceptable limits in 25%, 4%, 29%, 18%, 11%, 12%, and 7% of the evaluated units (n=28, respectively. Conclusion As radiographic X-ray equipments in Kerman province are relatively old with a high workload, it is recommended that AEOI modify the current policies by changing the frequency of QC test implementation to at least once a year.

  5. Employee quality, monitoring environment and internal control

    National Research Council Canada - National Science Library

    Chunli Liu Bin Lin Wei Shu

    2017-01-01

    ... quality.We examine the effect of monitoring on this result and find that the effect is more pronounced for firms with strict monitoring environments, especially when the firms implement the Chinese internal...

  6. Global Health Diplomacy, Monitoring & Evaluation, and the Importance of Quality Assurance & Control: Findings from NIMH Project Accept (HPTN 043): A Phase III Randomized Controlled Trial of Community Mobilization, Mobile Testing, Same-Day Results, and Post-Test Support for HIV in Sub-Saharan Africa and Thailand.

    Science.gov (United States)

    Kevany, Sebastian; Khumalo-Sakutukwa, Gertrude; Singh, Basant; Chingono, Alfred; Morin, Stephen

    2016-01-01

    Provision and scale-up of high quality, evidence-based services is essential for successful international HIV prevention interventions in order to generate and maintain intervention uptake, study integrity and participant trust, from both health service delivery and diplomatic perspectives. We developed quality assurance (QAC) procedures to evaluate staff fidelity to a cluster-randomized trial of the NIMH Project Accept (HPTN 043) assessing the effectiveness of a community-based voluntary counseling and testing strategy. The intervention was comprised of three components-Mobile Voluntary Counseling and Testing (MVCT), Community Mobilization (CM) and Post-Test Support Services (PTSS). QAC procedures were based on standardized criteria, and were designed to assess both provider skills and adherence to the intervention protocol. Supervisors observed a random sample of 5% to 10% of sessions each month and evaluated staff against multiple criteria on scales of 1-5. A score of 5 indicated 100% adherence, 4 indicated 95% adherence, and 3 indicated 90% adherence. Scores below 3 were considered unsatisfactory, and protocol deviations were discussed with the respective staff. During the first year of the intervention, the mean scores of MVCT and CM staff across the 5 study sites were 4 (95% adherence) or greater and continued to improve over time. Mean QAC scores for the PTSS component were lower and displayed greater fluctuations. Challenges to PTSS staff were identified as coping with the wide range of activities in the PTSS component and the novelty of the PTSS process. QAC fluctuations for PTSS were also associated with new staff hires or changes in staff responsibilities. Through constant staff monitoring and support, by Year 2, QAC scores for PTSS activities had reached those of MVCT and CM. The implementation of a large-sale, evidence based HIV intervention requires extensive QAC to ensure implementation effectiveness. Ongoing appraisal of study staff across sites

  7. Global Health Diplomacy, Monitoring & Evaluation, and the Importance of Quality Assurance & Control: Findings from NIMH Project Accept (HPTN 043: A Phase III Randomized Controlled Trial of Community Mobilization, Mobile Testing, Same-Day Results, and Post-Test Support for HIV in Sub-Saharan Africa and Thailand.

    Directory of Open Access Journals (Sweden)

    Sebastian Kevany

    Full Text Available Provision and scale-up of high quality, evidence-based services is essential for successful international HIV prevention interventions in order to generate and maintain intervention uptake, study integrity and participant trust, from both health service delivery and diplomatic perspectives.We developed quality assurance (QAC procedures to evaluate staff fidelity to a cluster-randomized trial of the NIMH Project Accept (HPTN 043 assessing the effectiveness of a community-based voluntary counseling and testing strategy. The intervention was comprised of three components-Mobile Voluntary Counseling and Testing (MVCT, Community Mobilization (CM and Post-Test Support Services (PTSS. QAC procedures were based on standardized criteria, and were designed to assess both provider skills and adherence to the intervention protocol. Supervisors observed a random sample of 5% to 10% of sessions each month and evaluated staff against multiple criteria on scales of 1-5. A score of 5 indicated 100% adherence, 4 indicated 95% adherence, and 3 indicated 90% adherence. Scores below 3 were considered unsatisfactory, and protocol deviations were discussed with the respective staff.During the first year of the intervention, the mean scores of MVCT and CM staff across the 5 study sites were 4 (95% adherence or greater and continued to improve over time. Mean QAC scores for the PTSS component were lower and displayed greater fluctuations. Challenges to PTSS staff were identified as coping with the wide range of activities in the PTSS component and the novelty of the PTSS process. QAC fluctuations for PTSS were also associated with new staff hires or changes in staff responsibilities. Through constant staff monitoring and support, by Year 2, QAC scores for PTSS activities had reached those of MVCT and CM.The implementation of a large-sale, evidence based HIV intervention requires extensive QAC to ensure implementation effectiveness. Ongoing appraisal of study staff

  8. Quality Control of Biotechnological Inputs DetectingMycoplasma

    Directory of Open Access Journals (Sweden)

    Cristiane Netto

    2015-04-01

    Full Text Available The aim of this work was to study the Polymerase Chain Reaction (PCR as a tool of quality control of bovine sera and cellular cultures used in the biotechnological industry. A total of 46 samples of bovine sera derived from two slaughterhouses and 33 samples of BHK21 cells derived from two biotechnological industries were evaluated using the primers GPO-3 (sense and MGSO (antisense. The PCR technique sensibility analysis showed that 280 bp were amplified for the quantities of 50 ng to 0.006 ng of Micoplasma DNA. The primers specificity was confirmed in the test using Staphylococcus aureus, Escherichia coli, Bacillus subtilisand Candida albicans; except by the positive control, none of the samples showed amplification. The presence of Mycoplasma in bovine sera and in the cultures of BHK21 cells showed that 56.5 and 15.2%, respectively, were contaminated. Thus, it was possible to conclude that PCR was a fast and confident technique to detect mycoplasma and that it could be used to control the quality of immunobiological products and inputs, such as sera and cultures of BHK21 cells.

  9. Achieving the Health Care Financing Administration limits by quality improvement and quality control. A real-world example.

    Science.gov (United States)

    Engebretson, M J; Cembrowski, G S

    1992-07-01

    With the enactment of the Clinical Laboratory Improvement Amendments of 1988 (CLIA 88), the federal government is now using proficiency testing as the primary indicator of laboratory quality. Laboratories with proficiency test failures are now at risk of a variety of harsh penalties including large monetary fines and suspension of operations. To minimize the risk of failed proficiency testing, we initiated a continuous quality improvement program in our general chemistry laboratory in conjunction with the use of a new survey-validated quality control product. This article describes the quality improvement program and our success in reducing the long-term random error in general chemistry. Despite our improvement program, significant analytical errors (greater than 30% of the CLIA limits) still exist in analytes measured by our chemistry analyzer. These errors are present in nearly the same analytes measured by other common chemistry analyzers indicating the need for improvement in their design and manufacture.

  10. Managing Air Quality - Multi-Pollutant Planning and Control

    Science.gov (United States)

    Describes how planning controls for multiple pollutants at the same time can save money and time and achieve significant benefits, and how control strategies can address both climate change and air quality.

  11. Teaching Quality Control with Chocolate Chip Cookies

    Science.gov (United States)

    Baker, Ardith

    2014-01-01

    Chocolate chip cookies are used to illustrate the importance and effectiveness of control charts in Statistical Process Control. By counting the number of chocolate chips, creating the spreadsheet, calculating the control limits and graphing the control charts, the student becomes actively engaged in the learning process. In addition, examining…

  12. Teaching Quality Control with Chocolate Chip Cookies

    Science.gov (United States)

    Baker, Ardith

    2014-01-01

    Chocolate chip cookies are used to illustrate the importance and effectiveness of control charts in Statistical Process Control. By counting the number of chocolate chips, creating the spreadsheet, calculating the control limits and graphing the control charts, the student becomes actively engaged in the learning process. In addition, examining…

  13. Online Test and Fault Diagnosis of Yarn Quality Using Wavelet Analysis And FFT

    Institute of Scientific and Technical Information of China (English)

    HONG Xi-jun; QiU Hao-bo; LI Yu-ming; LI Cong-xin

    2002-01-01

    A new online system of monitoring yarn quality and fault diagnosis is presented. This system integrates the technologies of sensor, signal process, commuunication,network, computer, control, instrument structure and mass knowledge of expert. Comparing with conventional off. Line yarn test, the new systemcan find the quality defects of yarn online in time and compensate for the lack of expert knowledge in manual analysis. It can save a lot of yarn wasted in off- line test and improve product quality. By using laser sensor to sample the diameter signal of yarn and doing wavelet analysis and FFT to extract fault characteristics, a set of reasoning mechanism is established to aralyze yarn quality and locate the fault origination. The experimental results show that new system can do well in monitoring yarn quality online comparing with conventional off-line yarn test. It can test the quality of yarn in real-time with high efficiency and analyze the fault reason accurately. It is very useful to apply this new system to upgrade yarn quality in cotton textile industry at present.

  14. [On-site quality control of acupuncture randomized controlled trial: design of content and checklist of quality control based on PICOST].

    Science.gov (United States)

    Li, Hong-Jiao; He, Li-Yun; Liu, Zhi-Shun; Sun, Ya-Nan; Yan, Shi-Yan; Liu, Jia; Zhao, Ye; Liu, Bao-Yan

    2014-02-01

    To effectively guarantee quality of randomized controlld trial (RCT) of acupuncture and develop reasonable content and checklist of on-site quality control, influencing factors on quality of acupuncture RCT are analyzed and scientificity of quality control content and feasibility of on-site manipulation are put into overall consideration. Based on content and checklist of on-site quality control in National 11th Five-Year Plan Project Optimization of Comprehensive Treatment Plan for TCM in Prevention and Treatment of Serious Disease and Clinical Assessment on Generic Technology and Quality Control Research, it is proposed that on-site quality control of acupuncture RCT should be conducted with PICOST (patient, intervention, comparison, out come, site and time) as core, especially on quality control of interveners' skills and outcome assessment of blinding, and checklist of on-site quality control is developed to provide references for undertaking groups of the project.

  15. Short communication: A printed image quality test phantom for mammography.

    Science.gov (United States)

    Kotre, C J; Porter, D J T

    2005-08-01

    This communication describes a novel design for a mammographic image quality test phantom, the final design of which was produced as a radiographer weekly quality assurance phantom for breast screening and symptomatic mammography. The phantom is based on low contrast test features which are built up by superimposing sheets of Mylar overhead projector transparency, on which the test features are printed using a standard LaserJet printer. The required radiation contrast at mammographic energies is produced by the approximately 50% by weight component of iron oxide (Fe(3)O(4)) present in the toner. An easily replicated design of mammographic image quality phantom based on LaserJet printed test features is described. Approximately 40 of these phantoms were constructed, and these have been used successfully for 5 years in both breast screening and symptomatic mammography. The phantom design offers a performance similar to much more expensive mammographic contrast-detail phantoms, but suffers from the disadvantage that high contrast resolution bar patterns cannot be produced using the standard printing process.

  16. Quality Control in Laboratory Hemostasis and Thrombosis

    Institute of Scientific and Technical Information of China (English)

    周立红; 刘泽霖

    2010-01-01

    @@ Introdution Laboratory diagnosis in medical practice,the position has been established,hernostasis and thrombosis.expefimental testing is no different.Experimental test of information not only for early diagnosis and guide treatment,prognosis and estimated recurrence.

  17. Quality control system response to stochastic growth of amyloid fibrils

    DEFF Research Database (Denmark)

    Pigolotti, Simone; Lizana, Ludvig; Otzen, Daniel

    2013-01-01

    We introduce a stochastic model describing aggregation of misfolded proteins and degradation by the protein quality control system in a single cell. Aggregate growth is contrasted by the cell quality control system, that attacks them at different stages of the growth process, with an efficiency t...

  18. 75 FR 41874 - Quality Control for Rental Assistance Subsidy Determinations

    Science.gov (United States)

    2010-07-19

    ... URBAN DEVELOPMENT Quality Control for Rental Assistance Subsidy Determinations AGENCY: Office of the.... This notice also lists the following information: Title of Proposal: Quality Control for Rental... agency's estimate of the burden of the proposed collection of information; (3) Enhance the...

  19. Artificial Intelligence Approach to Support Statistical Quality Control Teaching

    Science.gov (United States)

    Reis, Marcelo Menezes; Paladini, Edson Pacheco; Khator, Suresh; Sommer, Willy Arno

    2006-01-01

    Statistical quality control--SQC (consisting of Statistical Process Control, Process Capability Studies, Acceptance Sampling and Design of Experiments) is a very important tool to obtain, maintain and improve the Quality level of goods and services produced by an organization. Despite its importance, and the fact that it is taught in technical and…

  20. Safety of timber: An analysis of quality control options

    NARCIS (Netherlands)

    Kovryga, A.; Stapel, P.; Van de Kuilen, J.W.G.

    2014-01-01

    The quality assurance of timber properties is important for the safety of timber structures. In the current study, the quality control options of timber are analysed under the prism of the different growth regions. Therefore, these options - machine and output control - are simulated in accordance w

  1. Quality control of geological voxel models using experts' gaze

    NARCIS (Netherlands)

    Maanen, van Peter-Paul; Busschers, Freek S.; Brouwer, Anne-Marie; Meulendijk, van der Michiel J.; Erp, van Jan B.F.

    2015-01-01

    Due to an expected increase in geological voxel model data-flow and user demands, the development of improved quality control for such models is crucial. This study explores the potential of a new type of quality control that improves the detection of errors by just using gaze behavior of 12 geologi

  2. Control substances and alcohol use and testing

    Energy Technology Data Exchange (ETDEWEB)

    Przybylski, J.L.

    1994-07-01

    The Omnibus Transportation Employee Testing Act was signed into law in October of 1991. The Omnibus Transportation Employee Testing Act of 1991 required the United States Department of Transportation (DOT) to enact regulations requiring the testing of employees that perform ``safety sensitive functions`` for illegal controlled substance use and alcohol misuse. The Transportation Management Division, Office of Environmental Restoration and Waste Management (TMD/EM-261), United States Department of Energy (DOE), Training Program Manager is committed to promoting the availability of the necessary information to those affected members of the Department of Energy (DOE) community in an effort to attain the highest possible level of regulatory compliance and to enhance the safety of each individual in the workplace.

  3. Laboratory tests of sludge-control additives

    Energy Technology Data Exchange (ETDEWEB)

    Tatnall, R.E. [MIC Associates, Inc., Chadds Ford, PA (United States)

    1996-07-01

    Laboratory {open_quotes}jar{close_quotes} tests compared eleven different fuel oil and diesel fuel sludge-control additives. Factors studied included (1) ability to disperse and prevent buildup of sludge deposits on surfaces, (2) ability to protect steel from corrosion, (3) ability to inhibit growth and proliferation of bacteria, and (4) ability to disperse water. Results varied greatly, and it was found that many commercial products do not do what they claim. It is concluded that fuel retailers should not believe manufacturers` claims for their additive products, but rather should test such products themselves to be sure that the benefits of treatment are real. A simplified form of the procedure used here is proposed as one way for dealers to do such testing.

  4. Controlling acquiescence bias in measurement invariance tests

    Directory of Open Access Journals (Sweden)

    Aichholzer Julian

    2015-01-01

    Full Text Available Assessing measurement invariance (MI is an important cornerstone in establishing equivalence of instruments and comparability of constructs. However, a common concern is that respondent differences in acquiescence response style (ARS behavior could entail a lack of MI for the measured constructs. This study investigates if and how ARS impacts MI and the level of MI achieved. Data from two representative samples and two popular short Big Five personality scales were analyzed to study hypothesized ARS differences among educational groups. Multiple-group factor analysis and the random intercept method for controlling ARS are used to investigate MI with and without controlling for ARS. Results suggest that, contrary to expectations, controlling for ARS had little impact on conclusions regarding the level of MI of the instruments. Thus, the results suggest that testing MI is not an appropriate means for detecting ARS differences per se. Implications and further research areas are discussed.

  5. 西夏陵夯补支顶加固工艺质量控制研究%Quality Control Research on Reinforcement Technology Tests Using Rammed Earth to Fill Unsupported Walls in a Western Xia Imperial Tomb

    Institute of Scientific and Technical Information of China (English)

    张博; 王旭东; 郭青林; 裴强强; 杨善龙; 李凤洁

    2016-01-01

    土坯砌补与夯补支顶是西北干旱环境下加固土遗址悬空区常用的两种技术措施,对于夯筑类土遗址而言,夯补相较于砌补有明显的优势,既能保持遗址本体的原有工艺,避免土坯砌补表面处理层脱落露出砌补层影响观感,同时夯补体本身具有较强的稳定性和较强的抗风蚀、雨蚀能力。但是不同遗址夯土的建筑工艺、土的物理力学性质不同,施工过程中夯补质量无法准确控制。本文针对西夏陵遗址本体根部夯筑砌补,采用与原遗址相近的当地土,以固定质量夯锤为夯筑工具、并以传统人工夯实方法进行夯筑,分析研究夯土密度随铺土厚度和夯筑次数的变化规律,探索最佳铺土厚度和夯筑次数。试验结果表明,当使用2kg夯锤进行夯筑时,铺土厚度为12cm,垂直夯筑4次,即可得到密度较大且密度均匀的最佳夯筑效果。%There are two construction techniques frequently used in reinforcing unsupported regions of earthen structures in arid areas of northwest China:using adobe brick as a masonry complement, and filling the unsupported wall with rammed earth. For archaeological sites made of rammed earth, using soil to fill the top of a structure is better than using adobe brick because this technique is adopted from the original technology of the region and does not affect the physical appearance of the building. In addition, the rammed earth itself has strong stability and resistance to erosion caused by wind and rain. However, the quality of rammed earth cannot be controlled in the construction process precisely due to the different building techniques of the sites and the dif-ferent physical and mechanical properties of the soil. Focusing on the reinforcement of the foot of a wall of a Western Xia imperial tomb with rammed earth, this study utilizes local soil with the same properties of that used at the time, a pounding tool of fixed mass, and the

  6. Contributions of CCLM to advances in quality control.

    Science.gov (United States)

    Kazmierczak, Steven C

    2013-01-01

    Abstract The discipline of laboratory medicine is relatively young when considered in the context of the history of medicine itself. The history of quality control, within the context of laboratory medicine, also enjoys a relatively brief, but rich history. Laboratory quality control continues to evolve along with advances in automation, measurement techniques and information technology. Clinical Chemistry and Laboratory Medicine (CCLM) has played a key role in helping disseminate information about the proper use and utility of quality control. Publication of important advances in quality control techniques and dissemination of guidelines concerned with laboratory quality control has undoubtedly helped readers of this journal keep up to date on the most recent developments in this field.

  7. How to set up and manage quality control and quality assurance

    NARCIS (Netherlands)

    Visschedijk, M.; Hendriks, R.; Nuyts, K.

    2005-01-01

    This document provides a general introduction to clarify the differences between quality control (QC) and quality assurance (QA). In addition it serves as a starting point for implementing a quality system approach within an organization. The paper offers practical guidance to the implementation of

  8. How to set up and manage quality control and quality assurance

    NARCIS (Netherlands)

    Visschedijk, M.; Hendriks, R.; Nuyts, K.

    2005-01-01

    This document provides a general introduction to clarify the differences between quality control (QC) and quality assurance (QA). In addition it serves as a starting point for implementing a quality system approach within an organization. The paper offers practical guidance to the implementation of

  9. Pharmaceutical quality by design: product and process development, understanding, and control.

    Science.gov (United States)

    Yu, Lawrence X

    2008-04-01

    The purpose of this paper is to discuss the pharmaceutical Quality by Design (QbD) and describe how it can be used to ensure pharmaceutical quality. The QbD was described and some of its elements identified. Process parameters and quality attributes were identified for each unit operation during manufacture of solid oral dosage forms. The use of QbD was contrasted with the evaluation of product quality by testing alone. The QbD is a systemic approach to pharmaceutical development. It means designing and developing formulations and manufacturing processes to ensure predefined product quality. Some of the QbD elements include: Defining target product quality profile; Designing product and manufacturing processes; Identifying critical quality attributes, process parameters, and sources of variability; Controlling manufacturing processes to produce consistent quality over time. Using QbD, pharmaceutical quality is assured by understanding and controlling formulation and manufacturing variables. Product testing confirms the product quality. Implementation of QbD will enable transformation of the chemistry, manufacturing, and controls (CMC) review of abbreviated new drug applications (ANDAs) into a science-based pharmaceutical quality assessment.

  10. Technological options to control quality of fish burgers.

    Science.gov (United States)

    Danza, A; Conte, A; Del Nobile, M A

    2017-06-01

    This research was focused on preservation strategies applied to develop fish burgers enriched with tomato flour and extra-virgin olive oil. The effects of three different gas mixtures (5:95 O2/CO2; 10:60:30 O2/CO2/N2 and 5:50:45 O2/CO2/N2) on burger quality were analyzed by monitoring microbial cell load of main spoilage microorganisms, pH and sensory properties. As expected, modified atmosphere packaging significantly affected mesophilic bacteria with a reduction of about 2 log cycles for samples under 5% O2 and 95% CO2. Afterward, the best gas mixture was used in combination with various natural antimicrobial compounds (thymol, grape fruit seed extract and biocitrus). The biocitrus showed the strike balance between microbial and sensory quality, thus suggesting to be adopted for dipping treatment of the entire fish fillet before the mincing process. Later all the strategies tested individually were combined and samples were monitored for microbiological and sensory quality. Results obtained showed that dipping treatment of fillet in biocitrus solution (20,000 ppm) under modified conditions extended the shelf life by 8 days compared to the control sample, without affecting the sensory acceptability.

  11. Videoregistration of surgery should be used as a quality control.

    Science.gov (United States)

    Koninckx, Philippe R

    2008-01-01

    Quality control of medical treatment is strictly organized and supervised. Efficacy and safety have to be proven in large randomized controlled trials, which need ethical review board approval. Content and quality of marketed drugs is controlled by industry and government. After market introduction, postmarketing surveillance is organized. This quality control is necessary to obtain reliable and predictable results and to detect even rare adverse events. Quality control of surgical treatments is close to nonexistent for individual surgical procedures and, therefore, rare adverse events cannot be detected by the sheer number of interventions analyzed. An ethical review board is rarely consulted before a new procedure is attempted or introduced. Although the outcome of surgery is surgeon and environment dependent, the only estimation of quality is results and complication rates. These, however, reflect publications by dedicated groups or data from surveys that do not necessarily reflect reality accurately. Complications are known to be under-reported whereas surveys reflect mean quality only. For most complication rates, it remains unknown which were preventable mistakes and which were unavoidable, random accidents. This huge discrepancy in quality control of medical and surgical therapies can be understood by specifics of each type of therapy. Strict quality control in surgery is, moreover, difficult to organize given that the outcome varies with the surgeon and surgical environment. Systematic videotaping of entire interventions has the potential of providing a quality control of surgery. This, moreover, has become technically feasible at low cost. In conclusion, we need to reflect and organize quality control in surgery. Systematic videotaping of entire procedures seems to be an inexpensive and easy way to organize this control.

  12. [Study on seed quality test and quality standard of Pesudostellaria heterophylla].

    Science.gov (United States)

    Xiao, Cheng-Hong; Zhou, Tao; Jiang, Wei-Ke; Chen, Min; Xiong, Hou-Xi; Liao, Ming-Wu

    2014-08-01

    Referring to the rules for agricultural seed testing (GB /T 3543-1995) issued by China, the test of sampling, seed purity, weight per 1 000 seeds, seed moisture, seed viability and germination rate had been studied for screening seed quality test methods of Pesudostellaria heterophylla. The seed quality from different collection areas was measured. The results showed that at least 6.5 g seeds should be sampled and passed through 10-mesh sieve for purity analysis. The weight of 1 000 seeds was determined by using the 500-seed method. The phenotypic observation and size measurement were used for authenticity testing. The seed moisture was determined under the higher temperature (130 ± 2) degrees C for 5 hours. The seeds were dipped into 0.2% TTC sustaining 1 hour at 40 degrees C, then the viability could be determined. The break dormancy seeds were cultured on sand at 10 degrees C. K cluster analysis was applied for the data analysis, the seed quality from different collection areas grading of P. Heterophylla was described as three grades. The seed quality of each grade should reach following requirements: for first grade seeds, germination rate ≥ 86%, 1 000-grain weight ≥ 2.59 g, purity ≥ 87%, moisture ≤ 13.1%; for second grade seeds, germination rate ≥ 70%, 1 000-grain weight ≥ 2.40 g, purity ≥ 77%, moisture ≤ 14.3%; for third grade seeds, germination rate ≥ 41%, 1 000-grain weight ≥ 2.29 g, purity ≥ 76%, moisture ≤ 15.8%. The seed testing methods for quality items of P. heterophylla had been initially established, as well as the primary P. heterophylla seed quality classification standard.

  13. Development of energy-efficient comfort ventilation plants with air quality controlled volume flow rate and continuous detection of the status of the windows aperture. Part 3. Final report with documentation of the field test; Entwicklung energieeffizienter Komfortlueftungsanlagen mit luftqualitaetsgefuehrter Volumenstromregelung und kontinuierlicher Erfassung des Fensteroeffnungszustandes. Teilbericht 3. Endbericht mit Dokumentation des Feldtests

    Energy Technology Data Exchange (ETDEWEB)

    Grossklos, Marc; Hacke, Ulrike [Institut Wohnen und Umwelt GmbH, Darmstadt (Germany)

    2012-10-25

    Residential ventilation systems with a heat recovery contribute to the improvement of the air quality and to the reduction of heat losses caused by ventilation. An additional opening of the windows in residential buildings results in a clearly increasing consumption of thermal heat because the thermal heat of the out coming air cannot be utilized furthermore. Continuous information on the energetic effects of the opening of windows is helpful. Under this aspect, the authors of the contribution under consideration report on the development of energy efficient comfort ventilation systems with an air quality controlled volume flow rate and continuous detection of the status of the windows aperture. The contribution under consideration is the third part of a project concerning to this theme. This part encompasses a field test with four single-family houses in which the air quality control as well as the detection of the status of the windows aperture is tested and optimized for a long period. This contribution also contains the results of the second part of the project. The second project investigate the technical implementation of a air quality regulation at prototypes and test facilities.

  14. Greenhouse climate control affects postharvest tomato quality

    NARCIS (Netherlands)

    Farneti, B.; Schouten, R.E.; Qian, T.; Dieleman, J.A.; Tijskens, L.M.M.; Woltering, E.J.

    2013-01-01

    In this study, important quality properties such as firmness, sugar and acid levels were measured and analysed in tomatoes harvested from three greenhouses during a five month period and stored at 16 degrees C for over 20 days. Tomatoes were harvested from three identical, neighbouring, greenhouses

  15. PROCESS VARIABILITY REDUCTION THROUGH STATISTICAL PROCESS CONTROL FOR QUALITY IMPROVEMENT

    Directory of Open Access Journals (Sweden)

    B.P. Mahesh

    2010-09-01

    Full Text Available Quality has become one of the most important customer decision factors in the selection among the competing product and services. Consequently, understanding and improving quality is a key factor leading to business success, growth and an enhanced competitive position. Hence quality improvement program should be an integral part of the overall business strategy. According to TQM, the effective way to improve the Quality of the product or service is to improve the process used to build the product. Hence, TQM focuses on process, rather than results as the results are driven by the processes. Many techniques are available for quality improvement. Statistical Process Control (SPC is one such TQM technique which is widely accepted for analyzing quality problems and improving the performance of the production process. This article illustrates the step by step procedure adopted at a soap manufacturing company to improve the Quality by reducing process variability using Statistical Process Control.

  16. Methodical Grounds of Managing the Product Quality Control

    Directory of Open Access Journals (Sweden)

    Shapoval Olena A.

    2014-01-01

    Full Text Available The article analyses the modern state of products quality control management. It justifies a necessity of organisation of the quality control system under conditions of uninterrupted flow line production. It reveals problems connected with a low level of the products quality control management. It forms a set of factors of internal and external environments, which should be taken into account in the process of selection of a type of managerial actions by the products quality control. It considers specific features of identification of the most important factors at an enterprise on the basis of use of the matrix of strategic SWOT analysis. It offers a procedure of identification of a general assessment of factors of influence. It analyses a mechanism of use of main conceptual models, which reflect the system nature of quality management in an organisation – quality pyramids and quality loops. It proves a necessity of application of a principally new scheme of relations between the customer and enterprise, which envisages that requirements of the quality management system focus not on control and screening of semi-finished products, but on creation of conditions that exclude rejects. It considers the role of ISO 9000 in the system of quality management, which recommend the customers to make a preliminary assessment of activity of the producing enterprise.

  17. A task-based quality control metric for digital mammography

    Science.gov (United States)

    Maki Bloomquist, A. K.; Mainprize, J. G.; Mawdsley, G. E.; Yaffe, M. J.

    2014-11-01

    A reader study was conducted to tune the parameters of an observer model used to predict the detectability index (dʹ ) of test objects as a task-based quality control (QC) metric for digital mammography. A simple test phantom was imaged to measure the model parameters, namely, noise power spectrum, modulation transfer function and test-object contrast. These are then used in a non-prewhitening observer model, incorporating an eye-filter and internal noise, to predict dʹ. The model was tuned by measuring dʹ of discs in a four-alternative forced choice reader study. For each disc diameter, dʹ was used to estimate the threshold thicknesses for detectability. Data were obtained for six types of digital mammography systems using varying detector technologies and x-ray spectra. A strong correlation was found between measured and modeled values of dʹ, with Pearson correlation coefficient of 0.96. Repeated measurements from separate images of the test phantom show an average coefficient of variation in dʹ for different systems between 0.07 and 0.10. Standard deviations in the threshold thickness ranged between 0.001 and 0.017 mm. The model is robust and the results are relatively system independent, suggesting that observer model dʹ shows promise as a cross platform QC metric for digital mammography.

  18. New regulatory framework for wastewater quality control in Mexico.

    Science.gov (United States)

    Saade Hazin, L

    2000-01-01

    This paper analyses the new regulatory framework for wastewater quality control developed in Mexico. It provides a description of the Mexican government strategies for water pollution control. The discussion focuses on the policy instruments used, their evolution and the main difficulties encountered in their implementation. The new regulatory framework is discussed highlighting some of the economic implications of the reforms. The paper concludes that proper institutional development and monitoring are essential factors for the success of any policy instrument for wastewater quality control.

  19. Establishing a quality management system for unit-use testing based on NCCLS proposed guideline (EP18-P).

    Science.gov (United States)

    Whitley, R J; Santrach, P J; Phillips, D L

    2001-05-01

    Point of care tests often employ unit-use test devices. By their very nature (single use, disposable, self-contained) such devices present unique challenges for quality assurance (QA) and quality control (QC). The proposed NCCLS guideline (EP18-P) recommends a quality management system for unit-use testing. The document addresses regulatory considerations, proposes the development of a partnership between users and manufacturers, provides a source of error matrix, and suggests practical approaches to quality monitoring, identification and management of these potential problems. The key to the success of this guideline is cooperation and open exchange of information among manufacturers, users, regulators, and accrediting agencies.

  20. Totally Carrying out Zero Defects Quality Control

    Institute of Scientific and Technical Information of China (English)

    ZhangQingwei; CASCPresident

    2004-01-01

    Editorial note: On March 22,1992 the launch of LM-2E launch vehicle with an Australian satellite was terminated. A piece of 0.15 milligram aluminum redundance led to the malfunction of the program distributor, which caused the emergency cutoff after 7 seconds of the ignition of the rocket. To bear in mind the painful lesson, China Aerospace Corporation set out March 22 to be “Space Quality Day” in 1994.

  1. TL dosimetry for quality control of CR mammography imaging systems

    Science.gov (United States)

    Gaona, E.; Nieto, J. A.; Góngora, J. A. I. D.; Arreola, M.; Enríquez, J. G. F.

    The aim of this work is to estimate the average glandular dose with thermoluminescent (TL) dosimetry and comparison with quality imaging in computed radiography (CR) mammography. For a measuring dose, the Food and Drug Administration (FDA) and the American College of Radiology (ACR) use a phantom, so that dose and image quality are assessed with the same test object. The mammography is a radiological image to visualize early biological manifestations of breast cancer. Digital systems have two types of image-capturing devices, full field digital mammography (FFDM) and CR mammography. In Mexico, there are several CR mammography systems in clinical use, but only one system has been approved for use by the FDA. Mammography CR uses a photostimulable phosphor detector (PSP) system. Most CR plates are made of 85% BaFBr and 15% BaFI doped with europium (Eu) commonly called barium flourohalideE We carry out an exploratory survey of six CR mammography units from three different manufacturers and six dedicated X-ray mammography units with fully automatic exposure. The results show three CR mammography units (50%) have a dose greater than 3.0 mGy without demonstrating improved image quality. The differences between doses averages from TLD system and dosimeter with ionization chamber are less than 10%. TLD system is a good option for average glandular dose measurement for X-rays with a HVL (0.35-0.38 mmAl) and kVp (24-26) used in quality control procedures with ACR Mammography Accreditation Phantom.

  2. Results of the quality assurance testing program for radiopharmaceuticals 1995

    Energy Technology Data Exchange (ETDEWEB)

    Baldas, J.; Binnyman, J.; Ivanov, Z.; Lauder, R.

    1996-07-01

    The results of the quality assurance testing conducted by the Australian Radiation Laboratory is summarised. Overall 111 batches of 27 different types of radiopharmaceuticals were tested on samples obtained through normal commercial channels. Failure to meet full specifications was observed in 10 of the 111 batches. All technetium-99m cold kits were reconstituted according to the directions in the package insert using sodium pertechnetate ( {sup 99m}Tc) injection. Radionuclidic purity has been determined at the calibration time, except for Thallous [{sup 201}Tl] Chloride injection where the highest impurity level up to product expiry is quoted. Non-compliance of the vial label was observed in one of the ten batches failing specification and was the sole cause of product failure for this batch. Vial label non-compliance consisted of, absence of volume in the vial. Six batches failed the biodistribution test but in no case did this involve failure of the distribution for the target organs. tabs.

  3. Combined Control Scheme for Monitoring Quality Characteristics

    Directory of Open Access Journals (Sweden)

    Adekeye K.S.

    2014-07-01

    Full Text Available In the literature, the Exponentially Weighted Moving Average (EWMA and Exponentially Weighted Moving Variance (EMWV control schemes have been used separately to monitor the process average and process variability respectively. Here the two are combined and applied on simulated process with different level of variation. The control limit interval (CLI and the average run length (ARL were evaluated for the combined chart. The combined chart performed better than the two independently. Furthermore, an algorithm was developed for the two control charts and implemented on visual basic VB6.0. The obtained results show that the combined EWMA and EWMV control chart is very sensitive in detecting shift in production process and every shift in the process mean is always preceded by shift in the process variability.

  4. Three Rs Approaches in the Production and Quality Control of Fish Vaccines.

    Science.gov (United States)

    Midtlyng, Paul J; Hendriksen, Coenraad; Balks, Elisabeth; Bruckner, Lukas; Elsken, Lawrence; Evensen, Oystein; Fyrand, Kjetil; Guy, Allison; Halder, Marlies; Hawkins, Penny; Kisen, Gunn; Romstad, Anne Berit; Salonius, Kira; Smith, Patrick; Sneddon, Lynne U

    2011-03-01

    The workshop on Three Rs Approaches in the Production and Quality Control of Fish Vaccines aimed a) to identify animal tests currently stipulated for the production and quality control of fish vaccines and to highlight animal welfare concerns associated with these tests; b) to identify viable options to replace, reduce, and refine animal use for fish vaccine testing; and c) to discuss the way forward and set out how the Three Rs may be implemented without jeopardizing the quality of the vaccines. The workshop participants - experts from academia, regulatory authorities, a scientific animal welfare organization, and the fish vaccine industry - agreed that efforts should be undertaken to replace the vaccination-challenge batch potency testing with tests based on antigen quantification or antibody response tests. Regulatory requirements of questionable scientific value and relevance for the quality of fish vaccines, such as the re-testing of batches produced outside Europe, or the double-dose batch safety test, should be re-considered. As an immediate measure the design of the current animal tests should be evaluated and modified in the light of refinement and reduction, for example, the number of unprotected control fish in vaccination-challenge tests should be reduced to the minimum.

  5. Web quality control for lectures: Supercourse and Amazon.com.

    Science.gov (United States)

    Linkov, Faina; LaPorte, Ronald; Lovalekar, Mita; Dodani, Sunita

    2005-12-01

    Peer review has been at the corner stone of quality control of the biomedical journals in the past 300 years. With the emergency of the Internet, new models of quality control and peer review are emerging. However, such models are poorly investigated. We would argue that the popular system of quality control used in Amazon.com offers a way to ensure continuous quality improvement in the area of research communications on the Internet. Such system is providing an interesting alternative to the traditional peer review approaches used in the biomedical journals and challenges the traditional paradigms of scientific publishing. This idea is being explored in the context of Supercourse, a library of 2,350 prevention lectures, shared for free by faculty members from over 150 countries. Supercourse is successfully utilizing quality control approaches that are similar to Amazon.com model. Clearly, the existing approaches and emerging alternatives for quality control in scientific communications needs to be assessed scientifically. Rapid explosion of internet technologies could be leveraged to produce better, more cost effective systems for quality control in the biomedical publications and across all sciences.

  6. Standard Practice for Quality Management Systems for Nondestructive Testing Agencies

    CERN Document Server

    American Society for Testing and Materials. Philadelphia

    2009-01-01

    1.1 This practice covers general requirements for the establishment and maintenance of a quality management system for agencies engaged in nondestructive testing (NDT). 1.2 This practice utilizes criteria contained in Practice E 543. 1.3 This practice utilizes criteria contained in American National Standard ANSI/ISO/ASQ Q9001–2000, Quality management systems—Requirements. 1.4 This practice recognizes the importance of establishing minimum safety criteria. 1.5 The use of SI or inch-pound units, or combinations thereof, will be the responsibility of the technical committee whose standards are referred to in this standard. 1.6 This practice does not purport to address all of the safety concerns, if any, associated with its use. It is the responsibility of the user of this practice to establish appropriate safety and health practices and determine the applicability of regulatory limitations prior to use.

  7. An adaptive toolkit for image quality evaluation in system performance test of digital breast tomosynthesis

    Science.gov (United States)

    Zhang, Guozhi; Petrov, Dimitar; Marshall, Nicholas; Bosmans, Hilde

    2017-03-01

    Digital breast tomosynthesis (DBT) is a relatively new diagnostic imaging modality for women. Currently, various models of DBT systems are available on the market and the number of installations is rapidly increasing. EUREF, the European Reference Organization for Quality Assured Breast Screening and Diagnostic Services, has proposed a preliminary Guideline - protocol for the quality control of the physical and technical aspects of digital breast tomosynthesis systems, with an ultimate aim of providing limiting values guaranteeing proper performance for different applications of DBT. In this work, we introduce an adaptive toolkit developed in accordance with this guideline to facilitate the process of image quality evaluation in DBT performance test. This toolkit implements robust algorithms to quantify various technical parameters of DBT images and provides a convenient user interface in practice. Each test is built into a separate module with configurations set corresponding to the European guideline, which can be easily adapted to different settings and extended with additional tests. This toolkit largely improves the efficiency for image quality evaluation of DBT. It is also going to evolve with the development of protocols in quality control of DBT systems.

  8. Equivalence versus classical statistical tests in water quality assessments.

    Science.gov (United States)

    Ngatia, Murage; Gonzalez, David; San Julian, Steve; Conner, Arin

    2010-01-01

    To evaluate whether two unattended field organic carbon instruments could provide data comparable to laboratory-generated data, we needed a practical assessment. Null hypothesis statistical testing (NHST) is commonly utilized for such evaluations in environmental assessments, but researchers in other disciplines have identified weaknesses that may limit NHST's usefulness. For example, in NHST, large sample sizes change p-values and a statistically significant result can be obtained by merely increasing the sample size. In addition, p-values can indicate that observed results are statistically significantly different, but in reality the differences could be trivial in magnitude. Equivalence tests, on the other hand, allow the investigator to incorporate decision criteria that have practical relevance to the study. In this paper, we demonstrate the potential use of equivalence tests as an alternative to NHST. We first compare data between the two field instruments, and then compare the field instruments' data to laboratory-generated data using both NHST and equivalence tests. NHST indicated that the data between the two field instruments and the data between the field instruments and the laboratory were significantly different. Equivalence tests showed that the data were equivalent because they fell within a pre-determined equivalence interval based on our knowledge of laboratory precision. We conclude that equivalence tests provide more useful comparisons and interpretation of water quality data than NHST and should be more widely used in similar environmental assessments.

  9. VPLS Based Quality and Cost Control for Tennessee Eastman Process

    Institute of Scientific and Technical Information of China (English)

    宋凯; 王海清; 李平

    2005-01-01

    Product quality and operation cost control obtain increasing emphases in modern chemical system engineering. To improve the fault detection power of the partial least square (PLS) method for quality control, a new QRPV statistic is proposed in terms of the VP (variable importance in projection) indices of monitored process variables, which is significantly advanced over and different from the conventional Q statistic. QRPV is calculated only by the residuals of the remarkable process variables (RPVs). Therefore, it is the dominant relation between quality and RPV not all process variables (as in the case of the conventional PLS) that is monitored by this new VP-PLS (VPLS) method. The combination of QRPV and T2 statistics is applied to the quality and cost control of the Tennessee Eastman (TE) process, and weak faults can be detected as quickly as possible. Consequently, the product quality of TE process is guaranteed and operation costs are reduced.

  10. Quality control of 5mg diazepam suppositories manipulated in the city of Campos Goytacazes – RJ

    Directory of Open Access Journals (Sweden)

    Renata Aparecida Venturi Canzian

    2012-10-01

    Full Text Available Diazepam suppositories are widely used by children and elderly, and require close attention to quality control because it is a controlled prescription drug. The objective of the study was to analyze diazepam suppositories manipulated in Campos dos Goytacazes, RJ, to verify if they are within the required quality standards, and offer safety and efficiency to patients. We analyzed samples of 5mg diazepam suppositories acquired in five randomly selected pharmacies, identified as Pharmacy A, Pharmacy B, Pharmacy C, Pharmacy D, and Pharmacy E. We ran tests on average weight, organoleptic control, hardness, melting point, and dissolution. Data was analyzed and compared with the requirements of the Brazilian Pharmacopoeia. This analysis was made over a table in Excel. We conclude that only C Pharmacy was approved in all tests, and this is the only laboratory that has analyzed the quality of the product warranty. Laboratories A, B, D and E have been approved in some tests, and failed one or more tests. To ensure quality control, suppositories needed to pass in all tests, which was not the case of these labs. Therefore, we recommended the following procedures to the investigated laboratories: changes in packaging, greater precision in handling, quality control prior to dispensing the product, and efficient pharmaceutical care service.

  11. Advancement in modern approaches to mineral production quality control

    Science.gov (United States)

    Freidina, EV; Botvinnik, AA; Dvornikova, AN

    2017-02-01

    The natural resource potential of mineral deposits is represented by three categories: upside, attainable and investment. A modern methodology is proposed in this paper for production quality control, and its tools aimed at ensuring agreement between the product quality and the market requirements are described. The definitions of the costs of the product quality compliance and incompliance with the consumer requirements are introduced; the latter is suggested to use in evaluating resource potential of mineral deposits at a certain degree of probability.

  12. K-type geomagnetic index nowcast with data quality control

    Directory of Open Access Journals (Sweden)

    René Warnant

    2011-07-01

    Full Text Available

    A nowcast system for operational estimation of a proxy K-type geomagnetic index is presented. The system is based on a fully automated computer procedure for real-time digital magnetogram data acquisition that includes screening of the dataset and removal of the outliers, estimation of the solar regular variation (SR of the geomagnetic field, calculation of the index, and issuing of an alert if storm-level activity is indicated. This is a time-controlled (rather than event-driven system that delivers the regular output of: the index value, the estimated quality flag, and eventually, an alert. The novel features provided are first, the strict control of the data input and processing, and second, the increased frequency of production of the index (every 1 h. Such quality control and increased time resolution have been found to be of crucial importance for various applications, e.g. ionospheric monitoring, that are of particular interest to us and to users of our service. The nowcast system operability, accuracy and precision have been tested with instantaneous measurements from recent years. A statistical comparison between the nowcast and the definitive index values shows that the average root-mean-square error is smaller than 1 KU. The system is now operational at the site of the Geophysical Centre of the Royal Meteorological Institute in Dourbes (50.1ºN, 4.6ºE, and it is being used for alerting users when geomagnetic storms take place.

  13. Electronic Quality of Life Assessment Using Computer-Adaptive Testing

    Science.gov (United States)

    2016-01-01

    Background Quality of life (QoL) questionnaires are desirable for clinical practice but can be time-consuming to administer and interpret, making their widespread adoption difficult. Objective Our aim was to assess the performance of the World Health Organization Quality of Life (WHOQOL)-100 questionnaire as four item banks to facilitate adaptive testing using simulated computer adaptive tests (CATs) for physical, psychological, social, and environmental QoL. Methods We used data from the UK WHOQOL-100 questionnaire (N=320) to calibrate item banks using item response theory, which included psychometric assessments of differential item functioning, local dependency, unidimensionality, and reliability. We simulated CATs to assess the number of items administered before prespecified levels of reliability was met. Results The item banks (40 items) all displayed good model fit (P>.01) and were unidimensional (fewer than 5% of t tests significant), reliable (Person Separation Index>.70), and free from differential item functioning (no significant analysis of variance interaction) or local dependency (residual correlations banks were between 45% and 75% shorter than paper-based WHOQOL measures. Across the four domains, a high standard of reliability (alpha>.90) could be gained with a median of 9 items. Conclusions Using CAT, simulated assessments were as reliable as paper-based forms of the WHOQOL with a fraction of the number of items. These properties suggest that these item banks are suitable for computerized adaptive assessment. These item banks have the potential for international development using existing alternative language versions of the WHOQOL items. PMID:27694100

  14. Electronic Quality of Life Assessment Using Computer-Adaptive Testing.

    Science.gov (United States)

    Gibbons, Chris; Bower, Peter; Lovell, Karina; Valderas, Jose; Skevington, Suzanne

    2016-09-30

    Quality of life (QoL) questionnaires are desirable for clinical practice but can be time-consuming to administer and interpret, making their widespread adoption difficult. Our aim was to assess the performance of the World Health Organization Quality of Life (WHOQOL)-100 questionnaire as four item banks to facilitate adaptive testing using simulated computer adaptive tests (CATs) for physical, psychological, social, and environmental QoL. We used data from the UK WHOQOL-100 questionnaire (N=320) to calibrate item banks using item response theory, which included psychometric assessments of differential item functioning, local dependency, unidimensionality, and reliability. We simulated CATs to assess the number of items administered before prespecified levels of reliability was met. The item banks (40 items) all displayed good model fit (P>.01) and were unidimensional (fewer than 5% of t tests significant), reliable (Person Separation Index>.70), and free from differential item functioning (no significant analysis of variance interaction) or local dependency (residual correlations .90) could be gained with a median of 9 items. Using CAT, simulated assessments were as reliable as paper-based forms of the WHOQOL with a fraction of the number of items. These properties suggest that these item banks are suitable for computerized adaptive assessment. These item banks have the potential for international development using existing alternative language versions of the WHOQOL items.

  15. Testing a Personal Narrative for Persuading People to Value and Use Comparative Physician Quality of Care Information: An Experimental Study.

    Science.gov (United States)

    Greene, Jessica; Hibbard, Judith H; Sacks, Rebecca M

    2017-09-01

    This study tests whether a personal narrative can persuade people to value comparative data on physician quality. We conducted an online experiment with 850 adults. One group viewed a cartoon narrative on physician quality variation, another saw text on physician quality variation, and there was a control group. Study participants hypothetically selected a physician from a display of four physicians. The top-quality physician was furthest away and most expensive. We conducted multivariate models examining the relationship between experimental group and choice of the top-quality physician. There was no overall relationship between narrative or text information and choice of the highest quality physician. Among higher numerate participants, however, those who viewed the narrative had odds 2.7 times higher of selecting the top-quality physician compared with the control group. Personal narratives can persuade higher numerate people to consider quality when selecting physicians.

  16. Academic Quality Control in Nigerian Universities: Exploring Lecturers' Perceptions

    Science.gov (United States)

    Obiekezie, E. O.; Ejemot-Nwadiaro, R. I.; Essien, M. I.; Timothy, A. Essien

    2014-01-01

    The level of job performance, international comparability and competitiveness of Nigerian university graduates are burning issues. Consequently, the academic quality of Nigerian universities has come under severe criticism. Since university lecturers are key players in quality control in universities, this study explored their perceptions of…

  17. Academic Quality Control in Nigerian Universities: Exploring Lecturers' Perceptions

    Science.gov (United States)

    Obiekezie, E. O.; Ejemot-Nwadiaro, R. I.; Essien, M. I.; Timothy, A. Essien

    2014-01-01

    The level of job performance, international comparability and competitiveness of Nigerian university graduates are burning issues. Consequently, the academic quality of Nigerian universities has come under severe criticism. Since university lecturers are key players in quality control in universities, this study explored their perceptions of…

  18. Quality control for diagnostic oral microbiology laboratories in European countries

    NARCIS (Netherlands)

    Rautemaa-Richardson, R.; van der Reijden, W.A.; Dahlen, G.; Smith, A.J.

    2011-01-01

    Participation in diagnostic microbiology internal and external quality control (QC) processes is good laboratory practice and an essential component of a quality management system. However, no QC scheme for diagnostic oral microbiology existed until 2009 when the Clinical Oral Microbiology (COMB)

  19. Quality Changes of Frozen Meat During Storage and Control Measures

    Institute of Scientific and Technical Information of China (English)

    DU Jiangping

    2010-01-01

    The frozen is a common method of meat storage, generally applications in meat industrial. However, the quality of meat still have taken place changes even in the low temperature, This article discussion on the changes of frozen meat quality during freezing storage, and give the corresponding control measures.

  20. Quality Control Review of the Defense Logistics Agency Audit Organization

    Science.gov (United States)

    2014-12-19

    all auditors are required to follow, and established an internal quality assurance division that performs ongoing, periodic assessments of work...audit organization performing audits or attestation engagements or both have an appropriate internal quality control system in place and undergo an...2010, the DLA OIG addressed our recommendation to implement official policies and procedures, which all auditors are required to follow. The DLA

  1. Modeling of the CIGRE Low Voltage Test Distribution Network and the Development of Appropriate Controllers

    DEFF Research Database (Denmark)

    Mustafa, Ghullam; Bak-Jensen, Birgitte; Mahat, Pukar

    2013-01-01

    controller. The control system is tested in the distribution test network set up by CIGRE. The new approach of the PV controller is done in such a way that it can control AC and DC voltage of the PV converter during dynamic conditions. The battery controller is also developed in such a way that it can...... quality issues. The main focus of this paper is on development of controllers for a distribution system with different DG’s and especially development of a Photovoltaic (PV) controller using a Static Compensator (STATCOM) controller and on modeling of a Battery Storage System (BSS) also based on a STATCOM...

  2. Development of Quality Control Procedures for Lepidoptera

    Science.gov (United States)

    Lepidopteran species are among the most destructive insect pests throughout the world. The sterile insect technique (SIT), within an area-wide integrated pest management (AW-IPM) approach, has proven to be a valuable tactic for controlling and eradicating important moth pests. Improving laboratory...

  3. Cold plasma: Quality control and regulatory considerations

    Science.gov (United States)

    In recent years, cold plasma has emerged as a promising antimicrobial treatment for fresh and fresh-cut produce, nuts, spices, seeds, and other foods. Research has demonstrated effective control of human pathogens such as Salmonella, Listeria monocytogenes, Escherichia coli O157:H7, norovirus, and o...

  4. 7 CFR 58.138 - Quality testing of milk from new producers.

    Science.gov (United States)

    2010-01-01

    ... Service 1 Quality Specifications for Raw Milk § 58.138 Quality testing of milk from new producers. A quality examination and tests shall be made on the first shipment of milk from a producer shipping milk to... 7 Agriculture 3 2010-01-01 2010-01-01 false Quality testing of milk from new producers....

  5. NOAA Ship Fairweather Underway Meteorological Data, Quality Controlled

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — NOAA Ship Fairweather Underway Meteorological Data (delayed ~10 days for quality control) are from the Shipboard Automated Meteorological and Oceanographic System...

  6. Research Ship Healy Underway Meteorological Data, Quality Controlled

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Research Ship Healy Underway Meteorological Data (delayed ~10 days for quality control) are from the Shipboard Automated Meteorological and Oceanographic System...

  7. Research Ship Atlantis Underway Meteorological Data, Quality Controlled

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Research Ship Atlantis Underway Meteorological Data (delayed ~10 days for quality control) are from the Shipboard Automated Meteorological and Oceanographic System...

  8. NOAA Ship David Starr Jordan Underway Meteorological Data, Quality Controlled

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — NOAA Ship David Starr Jordan Underway Meteorological Data (delayed ~10 days for quality control) are from the Shipboard Automated Meteorological and Oceanographic...

  9. NOAA Ship Henry B. Bigelow Underway Meteorological Data, Quality Controlled

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — NOAA Ship Henry B. Bigelow Underway Meteorological Data (delayed ~10 days for quality control) are from the Shipboard Automated Meteorological and Oceanographic...

  10. NOAA Ship Delaware II Underway Meteorological Data, Quality Controlled

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — NOAA Ship Delaware II Underway Meteorological Data (delayed ~10 days for quality control) are from the Shipboard Automated Meteorological and Oceanographic System...

  11. NOAA Ship Ka'imimoana Underway Meteorological Data, Quality Controlled

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — NOAA Ship Ka'imimoana Underway Meteorological Data (delayed ~10 days for quality control) are from the Shipboard Automated Meteorological and Oceanographic System...

  12. Research Ship Laurence M. Gould Underway Meteorological Data, Quality Controlled

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Research Ship Laurence M. Gould Underway Meteorological Data (delayed ~10 days for quality control) are from the Shipboard Automated Meteorological and Oceanographic...

  13. NOAA Ship Oregon II Underway Meteorological Data, Quality Controlled

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — NOAA Ship Oregon II Underway Meteorological Data (delayed ~10 days for quality control) are from the Shipboard Automated Meteorological and Oceanographic System...

  14. NOAA Ship Miller Freeman Underway Meteorological Data, Quality Controlled

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — NOAA Ship Miller Freeman Underway Meteorological Data (delayed ~10 days for quality control) are from the Shipboard Automated Meteorological and Oceanographic System...

  15. NOAA Ship Pisces Underway Meteorological Data, Quality Controlled

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — NOAA Ship Pisces Underway Meteorological Data (delayed ~10 days for quality control) are from the Shipboard Automated Meteorological and Oceanographic System (SAMOS)...

  16. Research Ship Roger Revelle Underway Meteorological Data, Quality Controlled

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Research Ship Roger Revelle Underway Meteorological Data (delayed ~10 days for quality control) are from the Shipboard Automated Meteorological and Oceanographic...

  17. Research Ship T. G. Thompson Underway Meteorological Data, Quality Controlled

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Research Ship T. G. Thompson Underway Meteorological Data (delayed ~10 days for quality control) are from the Shipboard Automated Meteorological and Oceanographic...

  18. Research Ship Kilo Moana Underway Meteorological Data, Quality Controlled

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Research Ship Kilo Moana Underway Meteorological Data (delayed ~10 days for quality control) are from the Shipboard Automated Meteorological and Oceanographic System...

  19. Research Ship Southern Surveyor Underway Meteorological Data, Quality Controlled

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Research Ship Southern Surveyor Underway Meteorological Data (delayed ~10 days for quality control) are from the Shipboard Automated Meteorological and Oceanographic...

  20. Research Ship New Horizon Underway Meteorological Data, Quality Controlled

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Research Ship New Horizon Underway Meteorological Data (delayed ~10 days for quality control) are from the Shipboard Automated Meteorological and Oceanographic...

  1. NOAA Ship Okeanos Explorer Underway Meteorological Data, Quality Controlled

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — NOAA Ship Okeanos Explorer Underway Meteorological Data (delayed ~10 days for quality control) are from the Shipboard Automated Meteorological and Oceanographic...

  2. Research Ship Nathaniel B. Palmer Underway Meteorological Data, Quality Controlled

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Research Ship Nathaniel B. Palmer Underway Meteorological Data (delayed ~10 days for quality control) are from the Shipboard Automated Meteorological and...

  3. Research Ship Aurora Australis Underway Meteorological Data, Quality Controlled

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Research Ship Aurora Australis Underway Meteorological Data (delayed ~10 days for quality control) are from the Shipboard Automated Meteorological and Oceanographic...

  4. NOAA Ship Ronald Brown Underway Meteorological Data, Quality Controlled

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — NOAA Ship Ronald Brown Underway Meteorological Data (delayed ~10 days for quality control) are from the Shipboard Automated Meteorological and Oceanographic System...

  5. NOAA Ship Nancy Foster Underway Meteorological Data, Quality Controlled

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — NOAA Ship Nancy Foster Underway Meteorological Data (delayed ~10 days for quality control) are from the Shipboard Automated Meteorological and Oceanographic System...

  6. Research Ship Tangaroa Underway Meteorological Data, Quality Controlled

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Research Ship Tangaroa Underway Meteorological Data (delayed ~10 days for quality control) are from the Shipboard Automated Meteorological and Oceanographic System...

  7. Research Ship Melville Underway Meteorological Data, Quality Controlled

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Research Ship Melville Underway Meteorological Data (delayed ~10 days for quality control) are from the Shipboard Automated Meteorological and Oceanographic System...

  8. Research Ship Atlantis Underway Meteorological Data, Quality Controlled

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Research Ship Atlantis Underway Meteorological Data (delayed ~10 days for quality control) are from the Shipboard Automated Meteorological and Oceanographic System...

  9. NOAA Ship Bell M. Shimada Underway Meteorological Data, Quality Controlled

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — NOAA Ship Bell M. Shimada Underway Meteorological Data (delayed ~10 days for quality control) are from the Shipboard Automated Meteorological and Oceanographic...

  10. NOAA Ship Rainier Underway Meteorological Data, Quality Controlled

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — NOAA Ship Rainier Underway Meteorological Data (delayed ~10 days for quality control) are from the Shipboard Automated Meteorological and Oceanographic System...

  11. NOAA Ship Hi'ialakai Underway Meteorological Data, Quality Controlled

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — NOAA Ship Hi'ialakai Underway Meteorological Data (delayed ~10 days for quality control) are from the Shipboard Automated Meteorological and Oceanographic System...

  12. sampling plans for monitoring quality control process at a plastic ...

    African Journals Online (AJOL)

    Dr Obe

    managing these -activities in an intercultural environment will be of increasing ... adoption of new managerial concepts and .techniques among ... sample for both monitoring and quality control purposes. Prybrutok, et al. 7 observed that the.

  13. Research Ship Robert Gordon Sproul Underway Meteorological Data, Quality Controlled

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Research Ship Robert Gordon Sproul Underway Meteorological Data (delayed ~10 days for quality control) are from the Shipboard Automated Meteorological and...

  14. NOAA Ship Oscar Dyson Underway Meteorological Data, Quality Controlled

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — NOAA Ship Oscar Dyson Underway Meteorological Data (delayed ~10 days for quality control) are from the Shipboard Automated Meteorological and Oceanographic System...

  15. Research Ship Atlantic Explorer Underway Meteorological Data, Quality Controlled

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Research Ship Atlantic Explorer Underway Meteorological Data (delayed ~10 days for quality control) are from the Shipboard Automated Meteorological and Oceanographic...

  16. NOAA Ship Oscar Elton Sette Underway Meteorological Data, Quality Controlled

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — NOAA Ship Oscar Elton Sette Underway Meteorological Data (delayed ~10 days for quality control) are from the Shipboard Automated Meteorological and Oceanographic...

  17. NOAA Ship Gordon Gunter Underway Meteorological Data, Quality Controlled

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — NOAA Ship Gordon Gunter Underway Meteorological Data (delayed ~10 days for quality control) are from the Shipboard Automated Meteorological and Oceanographic System...

  18. Research Ship Knorr Underway Meteorological Data, Quality Controlled

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Research Ship Knorr Underway Meteorological Data (delayed ~10 days for quality control) are from the Shipboard Automated Meteorological and Oceanographic System...

  19. Ensuring quality control of forensic accounting for efficient and ...

    African Journals Online (AJOL)

    Ensuring quality control of forensic accounting for efficient and effective ... has taken the center stage in every discussion whether in business or social. ... To ensure a valid conclusion of the study the ex-post facto research design was applied.

  20. Research Ship Oceanus Underway Meteorological Data, Quality Controlled

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Research Ship Oceanus Underway Meteorological Data (delayed ~10 days for quality control) are from the Shipboard Automated Meteorological and Oceanographic System...

  1. 微生物检验标本不合格原因分析及质控对策%Disqualification Cause of Microbiological Testing and Quality Control Samples Strategies

    Institute of Scientific and Technical Information of China (English)

    吴波

    2015-01-01

    Objective To analyze samples for microbiological examination failed to present valid reasons for countermea-sures; Methods A retrospective analysis of microbial specimens testing samples of the CDC in January 2014 to January 2015 carried out a total of 450 parts, microbiological testing of unqualified specimen copies statistics, and analyze the rea-sons for the emergence of the problem, in order to provide the basis for the proposed targeted countermeasures. Results In total 450 samples for microbiological examination, a total of 99 unsatisfactory samples, 22.00% of the total number of copies. In this part of the unsatisfactory samples, the water quality test specimen 34, accounting for 34.34%; 32 samples failed public health supplies, accounting for 32.32%; disposable tableware disinfection specimen 11, accounting for 11.11 percent; the remaining 22 parts of air test specimens,accounting for 22.22%. Conclusion This study concluded that for prone to problems of microbiological testing specimens should further increase the inspection efforts, at the same time, it should strengthen the coordination to make the submission process by doing all norms between the various departments, so that it can effectively reduce microbiological test specimen failure probability. Worthy of clinical application.%目的:通过分析微生物检验标本不合格的原因来提出有效的解决对策。方法回顾性分析该疾控中心于2014年1月-2015年1月所进行的微生物标本检验样本共计450份,对不合格的微生物检验标本份数进行统计,并分析出现问题的原因所在,以便于为具有针对性对策的提供依据。结果在共计450份微生物检验标本中,共有99份不合格样本,占总份数的22.00%。在这部分不合格样本中,水质检验标本34份,占34.34%;公共卫生用品不合格标本32份,占32.32%;一次性消毒餐具标本11份,占11.11%;其余22份为空气检验标本,占22.22%。结论通

  2. Mechanisms for quality control of misfolded transmembrane proteins

    OpenAIRE

    Houck, Scott A.; Cyr, Douglas M.

    2011-01-01

    To prevent the accumulation of misfolded and aggregated proteins, the cell has developed a complex network of cellular quality control (QC) systems to recognize misfolded proteins and facilitate their refolding or degradation. The cell faces numerous obstacles when performing quality control on transmembrane proteins. Transmembrane proteins have domains on both sides of a membrane and QC systems in distinct compartments must coordinate to monitor the folding status of the protein. Additionall...

  3. Analysis of Information Quality in event triggered Smart Grid Control

    DEFF Research Database (Denmark)

    Kristensen, Thomas le Fevre; Olsen, Rasmus Løvenstein; Rasmussen, Jakob Gulddahl

    2015-01-01

    dependability of existing networks. We develop models for network delays and information dynamics, and uses these to model information quality for three given information access schemes in an event triggered control scenario. We analyse the impact of model parameters, and show how optimal choice of information...... access scheme depends on network conditions as well as trade-offs between information quality, network resources and control reactivity....

  4. Quality control of injection moulded micro mechanical parts

    DEFF Research Database (Denmark)

    Gasparin, Stefania; Tosello, Guido; Hansen, Hans Nørgaard

    2009-01-01

    Quality control of micro components is an increasing challenge. Smaller mechanical parts are characterized by smaller tolerance to be verified. This paper focuses on the dimensional verification of micro injection moulded components selected from an industrial application. These parts are measured...... using an Optical Coordinate Measuring Machine (OCMM), which guarantees fast surface scans suitable for in line quality control. The uncertainty assessment of the measurements is calculated following the substitution method. To investigate the influence parameters in optical coordinate metrology two...

  5. Acceptance, commissioning and quality control in radiosurgery; Aceite, comissionamento e controle de qualidade em radiocirurgia

    Energy Technology Data Exchange (ETDEWEB)

    Toreti, Dalila Luzia

    2009-07-01

    Stereotactic Radiosurgery is a treatment technique that uses narrow beams of radiation focused with great accuracy in a small lesion. The introduction of micro multi leaf collimators (mMLC) allows this technique to reach a higher degree of dose conformation of the target lesion allowing a smaller irradiation of critical structures and normal tissues. This paper presents the results of the acceptance tests and commissioning of a Varian 6EX linear accelerator dedicated to radiosurgery associated with the BrainLab micro multi leaf collimator installed in the Hospital das Clinicas da Faculdade de Medicina da USP (HC-FMUSP) and establish feasible quality assurance program for the services that employ this special technique. The results of the acceptance tests were satisfactory and are willing with the specifications provided by the manufacturer and the commissioning tests were within the international recommendations. The tests and measures that are part of quality control process should be specific to each treatment unit, and the need, frequency and levels of tolerance.

  6. Production control system specified quality sausage products

    Directory of Open Access Journals (Sweden)

    A. V. Tokarev

    2016-01-01

    Full Text Available The problem of management of production target in technological system of production of sausages of the set quality is considered in article. Decomposition of technological system is considered. Functions of management are allocated: formation of an optimum compounding of forcemeat, expert analysis of a compounding, laboratory analysis of a compounding and its statement. Information technology of interaction of these functions is offered. The mathematical problem definition of finding of an optimum compounding meat product with use of possible substitutes of ingredients is presented. This mathematical problem is a classical linear programming problem whose solution has the standard program. Since the manufacture of the finished product are various nonlinear effects are taken into account at the present time it is practically impossible, the methodology provided in this operation "Expert analysis of the formulation" and "Laboratory analysis of the finished product." An example of calculating the optimum alternative base recipe "Sausages “Viennese with cheese”" TS 9213-010-40155161-2002. For an alternative formulation demands were made at a cost of meat, the ingredient composition, as well as the final product organoleptic and physic-chemical indicators should comply with regulatory requirements "Sausages “Viennese with cheese”" TS 9213-010-40155161-2002. Indicator acid activity (pH calculated stuffing formulation should be in the range 6.0-6.3. As a partial replacement for the main raw material have been proposed acceptable substitutes. It was necessary to calculate on the basis of the formulation "Sausages “Viennese with cheese”" TS 9213-010-40155161-2002 optimal price and quality alternative formulation. As a result of depreciation of the value of alternative stuffing recipe was 14,5 % when all of the restrictions on the consumer properties. The proposed information technology implemented in the software package "Multi

  7. Quality control based on electrical resistivity measurements

    OpenAIRE

    Ferreira, Rui Miguel; Jalali, Said

    2006-01-01

    The electrical resistivity of concrete is one of the main parameters controlling the initiation and propagation of reinforcement corrosion. It is common knowledge that concrete electrical resistivity is mainly dependent on the w/c ratio (pore connectivity), volume and type of cement, temperature and the moisture. This research work studies the effect of specimen shape and temperature of measurement on electrical resistivity measurements of concrete using the four-point Werner electrode. In ad...

  8. Role of Protein Quality Control Failure in Alcoholic Hepatitis Pathogenesis

    Directory of Open Access Journals (Sweden)

    Samuel W. French

    2017-02-01

    Full Text Available The mechanisms of protein quality control in hepatocytes in cases of alcoholic hepatitis (AH including ufmylation, FAT10ylation, metacaspase 1 (Mca1, ERAD (endoplasmic reticulum-associated degradation, JUNQ (juxta nuclear quality control, IPOD (insoluble protein deposit autophagocytosis, and ER stress are reviewed. The Mallory–Denk body (MDB formation develops in the hepatocytes in alcoholic hepatitis as a consequence of the failure of these protein quality control mechanisms to remove misfolded and damaged proteins and to prevent MDB aggresome formation within the cytoplasm of hepatocytes. The proteins involved in the quality control pathways are identified, quantitated, and visualized by immunofluorescent antibody staining of liver biopsies from patients with AH. Quantification of the proteins are achieved by measuring the fluorescent intensity using a morphometric system. Ufmylation and FAT10ylation pathways were downregulated, Mca1 pathways were upregulated, autophagocytosis was upregulated, and ER stress PERK (protein kinase RNA-like endoplasmic reticulum kinase and CHOP (CCAAT/enhancer-binding protein homologous protein mechanisms were upregulated. In conclusion: Despite the upregulation of several pathways of protein quality control, aggresomes (MDBs still formed in the hepatocytes in AH. The pathogenesis of AH is due to the failure of protein quality control, which causes balloon-cell change with MDB formation and ER stress.

  9. [Analysis of the results of the SEIMC External Quality Control Program. Year 2008].

    Science.gov (United States)

    Serrano, María del Remedio Guna; Mira, Nieves Orta; de Gopegui, Enrique Ruiz; Ovies, María Rosario; Cardona, Concepción Gimeno; Pérez, José L

    2010-01-01

    The External Quality Control Program of the Spanish Society of Infectious Diseases and Clinical Microbiology (SEIMC) include controls for bacteriology, serology, mycology, parasitology, mycobacteria and virology. This article present the most relevant conclusions and lessons from the 2008 controls. As a whole, the results obtained in 2008 confirm the excellent skill and good technical standards of the microbiology laboratories in Spain found in previous editions. However, a few deviations can be obtained in any laboratory, even in clinically relevant determinations. Once again, the results of this program highlighted the need to implement both internal an external controls in order to assure the maximal quality of the microbiological tests.

  10. [Analysis of the results of the SEIMC External Quality Control Program. Year 2012].

    Science.gov (United States)

    de Gopegui Bordes, Enrique Ruiz; Guna Serrano, M del Remedio; Orta Mira, Nieves; Ovies, María Rosario; Poveda, Marta; Gimeno Cardona, Concepción

    2014-02-01

    The External Quality Control Program of the Spanish Society of Infectious Diseases and Clinical Microbiology (SEIMC) include controls for bacteriology, serology, mycology, parasitology, mycobacteria, virology and molecular microbiology. This article presents the most relevant conclusions and lessons from the 2012 controls. As a whole, the results obtained in 2012 confirm the excellent skill and good technical standards found in previous editions. However, erroneous results can be obtained in any laboratory and in clinically relevant determinations. Once again, the results of this program highlighted the need to implement both internal and external controls in order to assure the maximal quality of the microbiological tests.

  11. [Analysis of the results of the SEIMC External Quality Control Program. Year 2014].

    Science.gov (United States)

    Gopegui Bordes, Enrique Ruiz de; Guna Serrano, M Del Remedio; Orta Mira, Nieves; Medina González, Rafael; Rosario Ovies, María; Poveda, Marta; Gimeno Cardona, Concepción

    2016-07-01

    The External Quality Control Program of the Spanish Society of Infectious Diseases and Clinical Microbiology (SEIMC) include controls for bacteriology, serology, mycology, parasitology, mycobacteria, virology and molecular microbiology. This article presents the most relevant conclusions and lessons from the 2014 controls. As a whole, the results obtained in 2014 confirm the excellent skill and good technical standards found in previous editions. However, erroneous results can be obtained in any laboratory and in clinically relevant determinations. Once again, the results of the SEIMC program highlighted the need to implement both internal and external controls in order to assure the maximal quality of the microbiological tests.

  12. Quick Test for Evaluating Processed Food Quality (Short Communication

    Directory of Open Access Journals (Sweden)

    C. R. Vasudish

    2007-07-01

    Full Text Available Quick test for quality check of processed food will be handy for Defence Forces.  Aciditybeing one of the most important quality parameters, as per the ASC, BIS, PFA specifications,limits have been laid down as not to exceed 2 per cent in meat and fish products, 0.1 per centin cereal products, 1.25 per cent in ice cream powder, 1.5 per cent in milk powder, 0.3 per centin sweetened condensed milk, and 0.15 per cent in butter.  In the present study, a simple, quick,semi-quantitative test has been developed for checking acidity in processed foods to ascertaintheir quality.  The test is based on a colour reaction with the sample. The test solution givesblue to green to yellow colour depending on the concentration of acid in the sample.  Greencolour is the cut-off point for non-acceptance.  The large number of samples of meat (155, fishproducts (48, cereal products (222, ice cream powder (200, butter (200, milk powder (200 andsweetened condensed milk (202 were analysed by the quick test method and the results werecompared with those from the standard titrimetric method.  Acidity ranged form 0.68 per centto 2.40 per cent in meat products, 0.70 per cent to 2.50 per cent in fish products, 0.06 per centto 1.25 per cent in butter, 0.60 per cent to 1.91 per cent in milk powder, 0.05 per cent to 0.54 percent in ice cream powder, 0.32 per cent to 0.60 per cent in sweatened condensed milk, 0.05 percent to 1.10 per cent in cereal products. Some samples were found to be unacceptable havingacidity more than the specified limits.  The data were analysed statistically and the quick testwas found to correlate very well with the standard titrimetric method.

  13. Methane Lunar Surface Thermal Control Test

    Science.gov (United States)

    Plachta, David W.; Sutherlin, Steven G.; Johnson, Wesley L.; Feller, Jeffrey R.; Jurns, John M.

    2012-01-01

    NASA is considering propulsion system concepts for future missions including human return to the lunar surface. Studies have identified cryogenic methane (LCH4) and oxygen (LO2) as a desirable propellant combination for the lunar surface ascent propulsion system, and they point to a surface stay requirement of 180 days. To meet this requirement, a test article was prepared with state-of-the-art insulation and tested in simulated lunar mission environments at NASA GRC. The primary goals were to validate design and models of the key thermal control technologies to store unvented methane for long durations, with a low-density high-performing Multi-layer Insulation (MLI) system to protect the propellant tanks from the environmental heat of low Earth orbit (LEO), Earth to Moon transit, lunar surface, and with the LCH4 initially densified. The data and accompanying analysis shows this storage design would have fallen well short of the unvented 180 day storage requirement, due to the MLI density being much higher than intended, its substructure collapse, and blanket separation during depressurization. Despite the performance issue, insight into analytical models and MLI construction was gained. Such modeling is important for the effective design of flight vehicle concepts, such as in-space cryogenic depots or in-space cryogenic propulsion stages.

  14. Experience with ISO quality control in assisted reproductive technology.

    Science.gov (United States)

    Alper, Michael M

    2013-12-01

    Assisted reproductive technology (ART) programs are complex organizations requiring the integration of multiple disciplines. ISO 9001:2008 is a quality management system that is readily adaptable to an ART program. The value that ISO brings to the entire organization includes control of documents, clear delineation of responsibilities of staff members, documentation of the numerous processes and procedures, improvement in tracking and reducing errors, and overall better control of systems. A quality ART program sets quality objectives and monitors their progress. ISO provides a sense of transparency within the organization and clearer understanding of how service is provided to patients. Most importantly, ISO provides the framework to allow for continual improvement.

  15. Can water quality of tubewells be assessed without chemical testing?

    Science.gov (United States)

    Hoque, Mohammad A.; Butler, Adrian P.

    2016-04-01

    Arsenic is one of the major pollutants found in aquifers on a global scale. The screening of tubewells for arsenic has helped many people to avoid drinking from highly polluted wells in the Bengal Delta (West Bengal and Bangladesh). However, there are still many millions of tubewells in Bangladesh yet to be tested, and a substantial proportion of these are likely to contain excessive arsenic. Due to the level of poverty and lack of infrastructure, it is unlikely that the rest of the tubewells will be tested quickly. However, water quality assessment without needing a chemical testing may be helpful in this case. Studies have found that qualitative factors, such as staining in the tubewell basement and/or on utensils, can indicate subsurface geology and water quality. The science behind this staining is well established, red staining is associated with iron reduction leading to release of arsenic whilst black staining is associated with manganese reduction (any release of arsenic due to manganese reduction is sorbed back on the, yet to be reduced, iron), whereas mixed staining may indicate overlapping manganese and iron reduction at the tubewell screen. Reduction is not uniform everywhere and hence chemical water quality including dissolved arsenic varies from place to place. This is why coupling existing tubewell arsenic information with user derived staining data could be useful in predicting the arsenic status at a particular site. Using well location, depth, along with colour of staining, an assessment of both good (nutrients) and bad (toxins and pathogens) substances in the tubewell could be provided. Social-network technology, combined with increasing use of smartphones, provides a powerful opportunity for both sharing and providing feedback to the user. Here we outline how a simple digital application can couple the reception both qualitative and quantitative tubewell data into a centralised interactive database and provide manipulated feedback to an

  16. Using a tandem ionization chamber for quality control of X-ray beams

    Energy Technology Data Exchange (ETDEWEB)

    Yoshizumi, Maira T.; Caldas, Linda V.E., E-mail: mairaty@ipen.br [Instituto de Pesquisas Energeticas e Nucleares (IPEN/CNEN-SP), Sao Paulo, SP (Brazil)

    2011-07-01

    X-ray beam qualities are defined by both the mean energies and by the half-value layers (HVL). Many international protocols use the half-value layer and the beam voltage to characterize the X-ray beam quality. A quality control program for X-ray equipment includes the constancy check of beam qualities, i.e., the periodical verification of the half-value layer, which can be a time consumable procedure. A tandem ionization chamber, developed at Instituto de Pesquisas Energeticas e Nucleares, was used to determine the HVL and its constancy for five radiotherapy standard beam qualities. This ionization chamber is composed by two sensitive volumes with inner electrodes made of different materials: aluminum and graphite. The beam quality constancy check test was performed during two months and the maximum variation obtained was 1.24% for the radiation beam quality T-10. This result is very satisfactory according to national recommendations. (author)

  17. Quality control throughout the production process of infant food.

    Science.gov (United States)

    Hamrin, Pia; Hoeft, Birgit

    2012-01-01

    The manufacture of infant food is a highly complex process and needs an effective quality control beyond classical in-process parameters and a final microbiological analysis. To ensure a safe end -product, various tools, such as the Hazard Analysis Critical Control Points (HACCP), have been developed to facilitate the management of food safety. Every single infant formula ingredient must have an excellent quality and safety approach because even if an ingredient is used in very small quantities in a single product, serious consequences may arise if the quality and product safety are not taken seriously by the ingredient manufacturer. The purpose of this article was twofold: firstly, to briefly describe existing Quality Management Systems and, secondly, to highlight the consequences of non-quality.

  18. Flying qualities - A costly lapse in flight-control design

    Science.gov (United States)

    Berry, D. T.

    1982-01-01

    Generic problems in advanced aircraft with advanced control systems which suffer from control sensitivity, sluggish response, and pilot-induced oscillation tendencies are examined, with a view to improving techniques for eliminating the problems in the design phase. Results of two NASA and NASA/AIAA workshops reached a consensus that flying qualities criteria do not match control system development, control system designers are not relying on past experience in their field, ground-based simulation is relied on too heavily, and communications between flying qualities and control systems engineers need improvement. A summation is offered in that hardware and software have outstripped the pilot's capacity to use the capabilities which new aircraft offer. The flying qualities data base is stressed to be dynamic, and continually redefining the man/machine relationships.

  19. Quality control of cemented waste forms

    Energy Technology Data Exchange (ETDEWEB)

    Slate, L.J.

    1994-12-31

    To insure that cemented radwaste remains immobilized after disposal, certain standards have been set in Europe by the Commission of the European Communities. One such standard is compressive strength. If the compressive strength can be predicted during the early curing stages, time and money can be saved and the quality of the final waste form guaranteed. It was determined that the 7- and 28-day compressive strength from radwaste cementation can be predicted during the mixing and early curing stages by at least three methods. The three that were studied were maturity, rheology, and impedance. Maturity is a temperature-to-time measurement, rheology is a shear stress-to-shear rate measurement, and impedance is the opposition offered to the flow of alternating current. These three methods were employed on five different cemented radwaste concentrations with three different water-to-cement ratios; thus, a total of 15 different mix designs were considered. The results showed that the impedance was the easiest to employ for an on-line process. The results of the impedance method showed a very good relationship between impedance and water-to-cement ratio; therefore, an accurate prediction of compressive strength of cemented radwaste can be drawn from this method. The results of the theology method were very good. The method showed that concrete conforms to the Bingham plastic rheologic model, and the theology method can be used to predict the compressive strength of cemented radwaste, but may be too cumbersome. The results of the maturity method were shown to be limited in accuracy for determining compressive strength.

  20. Quality control of cast brake discs

    Directory of Open Access Journals (Sweden)

    M. Stawarz

    2008-04-01

    Full Text Available The largest industrial application so far have the gray cast irons which are characterized by low tensile and bending strength, while at the same time they have good ultimate comprehensive strength. Additionally, the fatigue strength of gray cast irons is comparatively low and they are only to some extend sensitive for the surface waters effects. Cast iron is the material, which is comparatively easy to be processed, and for this reason – it is not expensive. Brake discs are exploited in particularly hard conditions. They must be resistant both against the thermal fatigue and abrasion wearing (at dry friction as well as against seizing, corrosion and mechanical load [1-3]. The gray cast iron, better than other materials, fulfills all the requirements necessary for making the material for the casts resistant against such tough conditions. This work reflects the researches aiming to define the quality of cast brake discs (ventilated and non-ventilated ones upon a period of their exploitation in real conditions. The following researches were performed: evaluations of the disc surface condition, measurement of disc thickness, examination of run – out flank and metallographic analysis. In order to more detailed recognition of mechanisms and reasons of brake discs wearing in real conditions, one should conduct additional examinations: computer analysis of the microstructure, chemical composition analysis, etc., as well as study of the technology of their production in foundries, where they are manufactured [4]. By obtaining the full set of the mentioned above data one can draw final conclusions and remove causes of possible defects.

  1. Quality control and quality assurance of micromegas readout boards for the ATLAS New Small Wheel

    CERN Document Server

    Nanda, Amit

    2016-01-01

    The resistive anode boards of the Micromegas detectors for ATLAS NSW upgrade, will be produced in industries. The anode boards will be thoroughly evaluated at CERN following a detailed quality control and quality assurance (QA/QC) procedure. The report describes thoroughly the procedures and the design of a small QC tool for easier measurements of electrical properties of the readout boards.

  2. Spatial regression test for ensuring temperature data quality in southern Spain

    Science.gov (United States)

    Estévez, J.; Gavilán, P.; García-Marín, A. P.

    2016-10-01

    Quality assurance of meteorological data is crucial for ensuring the reliability of applications and models that use such data as input variables, especially in the field of environmental sciences. Spatial validation of meteorological data is based on the application of quality control procedures using data from neighbouring stations to assess the validity of data from a candidate station (the station of interest). These kinds of tests, which are referred to in the literature as spatial consistency tests, take data from neighbouring stations in order to estimate the corresponding measurement at the candidate station. These estimations can be made by weighting values according to the distance between the stations or to the coefficient of correlation, among other methods. The test applied in this study relies on statistical decision-making and uses a weighting based on the standard error of the estimate. This paper summarizes the results of the application of this test to maximum, minimum and mean temperature data from the Agroclimatic Information Network of Andalusia (southern Spain). This quality control procedure includes a decision based on a factor f, the fraction of potential outliers for each station across the region. Using GIS techniques, the geographic distribution of the errors detected has been also analysed. Finally, the performance of the test was assessed by evaluating its effectiveness in detecting known errors.

  3. Quality control for diagnostic oral microbiology laboratories in European countries

    Directory of Open Access Journals (Sweden)

    Andrew J. Smith

    2011-11-01

    Full Text Available Participation in diagnostic microbiology internal and external quality control (QC processes is good laboratory practice and an essential component of a quality management system. However, no QC scheme for diagnostic oral microbiology existed until 2009 when the Clinical Oral Microbiology (COMB Network was created. At the European Oral Microbiology Workshop in 2008, 12 laboratories processing clinical oral microbiological samples were identified. All these were recruited to participate into the study and six laboratories from six European countries completed both the online survey and the first QC round. Three additional laboratories participated in the second round. Based on the survey, European oral microbiology laboratories process a significant (mean per laboratory 4,135 number of diagnostic samples from the oral cavity annually. A majority of the laboratories did not participate in any internal or external QC programme and nearly half of the laboratories did not have standard operating procedures for the tests they performed. In both QC rounds, there was a large variation in the results, interpretation and reporting of antibiotic susceptibility testing among the laboratories. In conclusion, the results of this study demonstrate the need for harmonisation of laboratory processing methods and interpretation of results for oral microbiology specimens. The QC rounds highlighted the value of external QC in evaluating the efficacy and safety of processes, materials and methods used in the laboratory. The use of standardised methods is also a prerequisite for multi-centre epidemiological studies that can provide important information on emerging microbes and trends in anti-microbial susceptibility for empirical prescribing in oro-facial infections.

  4. Results of the quality assurance testing program for radiopharmaceuticals, 1994

    Energy Technology Data Exchange (ETDEWEB)

    Baldas, J.; Bonnyman, J.; Ivanov, Z.; Lauder, R

    1995-08-01

    The Australian Radiation Laboratory conducts a Radiopharmaceutical Quality Assurance Test Program in which radiopharmaceuticals used in nuclear medicine in Australia are tested for compliance with specifications. Where the radiopharmaceutical is the subject of a monograph in the British Pharmacopoeia or the European Pharmacopoeia, then the specifications given in the Pharmacopoeia are adopted. In other cases the specifications quoted have been adopted by this Laboratory and have no legal status. It should be noted that unless stated otherwise, the specifications listed apply at all times up to product expiry. Radionuclidic purity has been determined at the calibration time, except for Thallous [{sup 201}Tl] Chloride injection where the highest impurity level up to product expiry is quoted. Samples for testing were obtained through commercial channels. All technetium-99m cold kits were reconstituted according to the directions in the package insert using Sodium Pertechnetate[{sup 99m}Tc] Injection. Methods used for testing are described in the report ARL/TR093 24 tabs.

  5. Production Quality Control Of Microfluidic Chip Designs

    DEFF Research Database (Denmark)

    Calaon, Matteo; Hansen, Hans Nørgaard; Tosello, Guido

    2012-01-01

    process chain, test geometries were designed and produced on the side of the functional features. The so called “Finger Print” of the lithography and molding processes was qualitatively and quantitatively evaluated through scanning electron microscopy and atomic force microscopy respectively. The entire......The challenge of fabricating geometries with critical dimensions ranging from few microns down to 10 nanometers with high production rate is delaying the development of nanotechnology based products. Diverse research works have shown the capability of technologies such as UV lithography, nano...... imprint lithography and e-beam lithography to produce micro and nano features. However, their application for tooling purposes is relatively new and the potential to produce nanometer features with high volume low cost production is enormous. Considering possible implementation in a mass production...

  6. Quality control of the documentation process in electronic economic activities

    Directory of Open Access Journals (Sweden)

    Krutova A.S.

    2017-06-01

    Full Text Available It is proved that the main tool that will provide adequate information resources e economic activities of social and economic relations are documenting quality control processes as the basis of global information space. Directions problems as formation evaluation information resources in the process of documentation, namely development tools assess the efficiency of the system components – qualitative assessment; development of mathematical modeling tools – quantitative evaluation. A qualitative assessment of electronic documentation of economic activity through exercise performance, efficiency of communication; document management efficiency; effectiveness of flow control operations; relationship management effectiveness. The concept of quality control process documents electronically economic activity to components which include: the level of workflow; forms adequacy of information; consumer quality documents; quality attributes; type of income data; condition monitoring systems; organizational level process documentation; attributes of quality, performance quality consumer; type of management system; type of income data; condition monitoring systems. Grounded components of the control system electronic document subjects of economic activity. Detected components IT-audit management system economic activity: compliance audit; audit of internal control; detailed multilevel analysis; corporate risk assessment methodology. The stages and methods of processing electronic transactions economic activity during condition monitoring of electronic economic activity.

  7. [Pharmaceutical product quality control and good manufacturing practices].

    Science.gov (United States)

    Hiyama, Yukio

    2010-01-01

    This report describes the roles of Good Manufacturing Practices (GMP) in pharmaceutical product quality control. There are three keys to pharmaceutical product quality control. They are specifications, thorough product characterization during development, and adherence to GMP as the ICH Q6A guideline on specifications provides the most important principles in its background section. Impacts of the revised Pharmaceutical Affairs Law (rPAL) which became effective in 2005 on product quality control are discussed. Progress of ICH discussion for Pharmaceutical Development (Q8), Quality Risk Management (Q9) and Pharmaceutical Quality System (Q10) are reviewed. In order to reconstruct GMP guidelines and GMP inspection system in the regulatory agencies under the new paradigm by rPAL and the ICH, a series of Health Science studies were conducted. For GMP guidelines, product GMP guideline, technology transfer guideline, laboratory control guideline and change control system guideline were written. For the GMP inspection system, inspection check list, inspection memo and inspection scenario were proposed also by the Health Science study groups. Because pharmaceutical products and their raw materials are manufactured and distributed internationally, collaborations with other national authorities are highly desired. In order to enhance the international collaborations, consistent establishment of GMP inspection quality system throughout Japan will be essential.

  8. Aplicabilidade do Teste de Ativação de Monócitos (MAT no Brasil: importância da sua utilização como teste para detecção de pirogênios no controle da qualidade de produtos injetáveis | Applicability of the Monocyte Activation Test (MAT in Brazil: the importance of its use as a test for the detection of pyrogens in the quality control of injectable products

    Directory of Open Access Journals (Sweden)

    Cristiane Caldeira da Silva

    2015-08-01

    Full Text Available O MAT (sigla do inglês Monocyte Activation Test é considerado um potencial substituto do Teste de Pirogênios, entretanto: i. não foi avaliado para um número suficiente de produtos; ii. faltam dados que possam garantir sua capacidade em detectar pirogênios não endotoxinas; e iii. deve ser realizada a validação do método para cada classe de produtos. O objetivo foi identificar as monografias que requerem testes de pirogenicidade e propor os produtos que têm por base somente o teste de pirogênios como um ponto de partida para futuros estudos. As monografias específicas nas Farmacopeias Americana, Europeia e Brasileira que recomendam o Teste de Pirogênios ou Teste de Endotoxina Bacteriana ou LAL (sigla do inglês Limulus Amebocyte Lysate foram: Teste de Pirogênios: 20 monografias na Americana, 37 na Europeia e 28 na Brasileira. LAL: 619 monografias na Americana, 157 na Europeia e 41 na Brasileira. Somente quatro produtos requerem testes de pirogenicidade nas três farmacopeias analisadas. O Teste de Pirogênios e LAL são recomendados em seis monografias na Brasileira e 15 na Europeia. Na Brasileira, a maior parte dessas monografias é referente a produtos biológicos, sugerindo, assim, que estes devam ser os primeiros a ser testados, uma vez que são ensaiados em animais. ----------------------------------------------------------------------------------------------- Monocyte Activation Test (MAT is thought to be a good replacement for rabbit pyrogen test (RPT; however, MAT remains controversial. MAT was not adequately evaluated in a sufficient number of products, and there is no sufficient data that support the ability of MAT to detect non-endotoxin pyrogens. Furthermore, MAT was used subject to validation for each specific product. The aim of this study was to identify in main pharmacopoeias, whose monographs require pyrogenicity tests, and propose those products for which only the rabbit pyrogen test is required to be used as a

  9. 40 CFR 81.112 - Charleston Intrastate Air Quality Control Region.

    Science.gov (United States)

    2010-07-01

    ... Quality Control Regions § 81.112 Charleston Intrastate Air Quality Control Region. The Charleston Intrastate Air Quality Control Region (South Carolina) consists of the territorial area encompassed by the... Quality Control Region: Region 1. 81.107Greenwood Intrastate Air Quality Control Region: Region 2....

  10. 40 CFR 81.88 - Billings Intrastate Air Quality Control Region.

    Science.gov (United States)

    2010-07-01

    ... Quality Control Regions § 81.88 Billings Intrastate Air Quality Control Region. The Metropolitan Billings Intrastate Air Quality Control Region (Montana) has been renamed the Billings Intrastate Air Quality Control... to by Montana authorities as follows: Sec. 481.168Great Falls Intrastate Air Quality Control...

  11. Performance evaluation by means of quality control of MRI system and comparison of institutions

    Energy Technology Data Exchange (ETDEWEB)

    Ogura, Akio [Kyoto City Hospital (Japan); Higashida, Mitsuji; Yamazaki, Masaru; Inoue, Hiroshi; Ishiguro, Akihiro

    2000-06-01

    To evaluate the performance of clinical magnetic resonance imaging systems, standard test procedures have been recommended by the NEMA, AAPM task group, EEC concerted research project, and others. The purpose of these standard tests is to determine system performance specifications, reference procedures for test acceptance, and periodic examination of quality control. However, the recommended measurements are very complicated when used for periodic quality control checks or comparisons with other systems. Therefore, we determined new standard test procedures that serve these purposes. Eleven clinical MRI systems in nine clinical facilities were evaluated using these new standard test sets. Results indicated that the measurement time was too short using the new test sets. However, through comparison with various MRI systems, the specificity of each system could be determined. (author)

  12. Experience in quality control of PET with source of germanium; Experiencia en control de calidad de PET con fuente de germanio

    Energy Technology Data Exchange (ETDEWEB)

    Minambres Moro, A.; Fernandez Leton, P.; Garcia Ruiz-Zorrilla, J.; Perez Moreno, J. M.; Zucca Aparicio, D.

    2013-07-01

    In our hospital, the quality guarantee program in Nuclear Medicine was implemented in 2007. In the section on control quality figure, along with monthly measures, daily tests of sensitivity and uniformity of a Siemens PET-CT Bio graph 6 with a cylindrical Ge68 source. In this work the results of these monthly tests between 2010 and 2012. (Author)

  13. Agricultural biological reference materials for analytical quality control

    Energy Technology Data Exchange (ETDEWEB)

    Ihnat, M.

    1986-01-01

    Cooperative work is under way at Agriculture Canada, US Department of Agriculture, and US National Bureau of Standards in an attempt to fill some of the gaps in the world repertoire of reference materials and to provide much needed control materials for laboratories' day to day operations. This undertaking involves the preparation and characterization of a number of agricultural and food materials for data quality control for inorganic constituents. Parameters considered in the development of these materials were material selection based on importance in commerce and analysis; techniques of preparation, processing, and packaging; physical and chemical characterization; homogeneity testing and quantitation (certification). A large number of agricultural/food products have been selected to represent a wide range of not only levels of sought-for constituents (elements) but also a wide range of matrix components such as protein, carbohydrate, dietary fiber, fat, and ash. Elements whose concentrations are being certified cover some two dozen major, minor, and trace elements of nutritional, toxicological, and environmental significance.

  14. Direct product quality control for energy efficient climate controlled transport of agro-material

    NARCIS (Netherlands)

    Verdijck, G.J.C.; Preisig, H.A.; Straten, van G.

    2005-01-01

    A (model-based) Product Quality Controller is presented for climate controlled operations involving agro-material, such as storage and transport. This controller belongs to the class of Model Predictive Controllers and fits in a previously developed hierarchical control structure. The new Product

  15. Application of indices Cp and Cpk to improve quality control capability in clinical biochemistry laboratories.

    Science.gov (United States)

    Chen, Ming-Shu; Wu, Ming-Hsun; Lin, Chih-Ming

    2014-04-30

    The traditional criteria for acceptability of analytic quality may not be objective in clinical laboratories. To establish quality control procedures intended to enhance Westgard multi-rules for improving the quality of clinical biochemistry tests, we applied the Cp and Cpk quality-control indices to monitor tolerance fitting and systematic variation of clinical biochemistry test results. Daily quality-control data of a large Taiwanese hospital in 2009 were analyzed. The test items were selected based on an Olympus biochemistry machine and included serum albumin, aspartate aminotransferase, cholesterol, glucose and potassium levels. Cp and Cpk values were calculated for normal and abnormal levels, respectively. The tolerance range was estimated with data from 50 laboratories using the same instruments and reagents. The results showed a monthly trend of variation for the five items under investigation. The index values of glucose were lower than those of the other items, and their values were usually <2. In contrast to the Cp value for cholesterol, Cpk of cholesterol was lower than 2, indicating a systematic error that should be further investigated. This finding suggests a degree of variation or failure to meet specifications that should be corrected. The study indicated that Cp and Cpk could be applied not only for monitoring variations in quality control, but also for revealing inter-laboratory qualitycontrol capability differences.

  16. Design and implementation of the STKOS quality-control system

    Institute of Scientific and Technical Information of China (English)

    Haixia; SUN; Danya; LI; Junlian; LI; Sizhu; WU; Tiejun; HU; Qing; QIAN

    2015-01-01

    Purpose: The aim of this study is to develop and implement a quality-control system to ensure authority control of the different knowledge units for the Scientific & Technological Knowledge Organization Systems(STKOS).Design/methodology/approach: First, we analyzed quality-control requirements based on the construction of the STKOS Metathesaurus. Then we designed a quality-control framework, the task management and transfer mechanism, and a service model. Afterwards, we carried out the experiments to check the rules and algorithms used in the system. Finally, the system was developed, and gradually optimized during its service.Findings: The quality-control system supports collaborative knowledge construction, as well as consistency checks of knowledge units with different granularity levels, including terminologies, relationships, and concepts. The system can be flexibly configured.Research limitations: The system is oriented to an English-language knowledge organization system, and may not perform well with Chinese-language systems and ontologies.Practical implications: The system can be used to support the construction of a single knowledge organization system, as well as data warehousing and interoperable knowledge organization systems. Originality/value: The STKOS quality-control system not only focuses on content building for the knowledge system, but also supports collaborative task management.

  17. Controlled release fertilizer improves quality of container longleaf pine seedlings

    Science.gov (United States)

    R. Kasten Dumroese; Jeff Parkhurst; James P. Barnett

    2005-01-01

    In an operational trial, increasing the amount of nitrogen (N) applied to container longleaf pine seedlings by incorporating controlled release fertilizer (CRF) into the media improved seedling growth and quality. Compared with control seedlings that received 40 mg N, seedlings receiving 66 mg N through CRF supplemented with liquid fertilizer had needles that were 4 in...

  18. Analytical techniques and quality control in biomedical trace element research

    DEFF Research Database (Denmark)

    Heydorn, K.

    1994-01-01

    The small number of analytical results in trace element research calls for special methods of quality control. It is shown that when the analytical methods are in statistical control, only small numbers of duplicate or replicate results are needed to ascertain the absence of systematic errors cau...

  19. Importance of critical evaluation in quality control of scintillation cameras;Importancia da avaliacao criteriosa no controle de qualidade de camaras de cintilacao

    Energy Technology Data Exchange (ETDEWEB)

    Menezes, V.O.; Machado, M.A.D.; Sampaio, L.J.L.; Silva, D.C. [Hospital Sao Rafael, Salvador, BR (Brazil)

    2009-07-01

    The evaluation of quality control results in nuclear medicine must be performed with a critical view over the conditions the tests are executed. This paper is a result of observations in the routine quality control where we set up didactic 'findings' to show the importance of evaluating critical situations while executing the procedures. (author)

  20. 食品卫生微生物质控定量检测样品的制备及结果评价分析%Preparation of food hygiene and microbiological quality control samples and analysis of the test results

    Institute of Scientific and Technical Information of China (English)

    炊慧霞; 张丁; 裴晓燕; 张秀丽

    2012-01-01

    目的:制备食品卫生微生物定量质控样品,并对检测结果进行分析和评价,为微生物质控定量检测工作的开展提供依据.方法:以奶粉为基质,滴加一定量的菌液后制成定量检测用的质控样品,低温保存运输,并应用同步试验的方法进行质控,完成对大肠菌群平板法计数、金黄色葡萄球菌平板法计数和阪崎肠杆菌MPN法计数的考核.利用复现性临界差值(CD)和复现性限(R)对实验室内和实验室间的数据分别进行评价.结果:室内计数结果80%~100%在控制范围内,室间计数结果83.33%~ 94.44%在控制范围内.结论:此次研究结果显示制备的质控样品对于大肠菌群及金黄色葡萄球菌平板法计数效果比较好,对于阪崎肠杆菌MPN法计数效果稍差.%Objective: Food hygiene and microbiological quality control samples were prepared, and the test results were evaluated and analyzed to provide the quantitative basis for microbiological quality control of food hygiene inspection. Methods: Quality control samples were prepared with milk powder as matrix and addition of a amount of broth composed of coliforms, staphylococcus and E. sakazakii, then preserved and transported in low temperature, and carried out quality control by synchronic test for quantitative detection of the three bacteria. Inter - laboratory and intra - laboratory data were evaluated by reproducibility critical difference ( CD) and reproducibility limits (R). Results: 80% ~ 100% of the intra - laboratory count result and 83. 33% ~ 94. 44% of the inter - laboratory count result were in the control range. Conclusion: The results show that the quality control samples are better for coliforms and Staphylococcus aureus count plate method but less effective for the MPN method of E. sakazakii count.