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Sample records for qi

  1. [Qi Gong: medicine or enlightenment?].

    Science.gov (United States)

    Sánchez, Viescas Javier

    2005-05-01

    According to Dr. Yang Jwing-Ming, the translation for Qi Gong would be "Whatever practice or study related with Qi which requires a lot of time and effort". Qi Gong is a practice which combines posture exercises, gestures, breathing and a mental attitude destined to make Qi circulate in order to preserve one's health, cure diseases and prolong life.

  2. Qi Baishi’s Descendant

    Institute of Scientific and Technical Information of China (English)

    1998-01-01

    THE former home of Qi Baishi’ stands in Kuache Alley in the Xicheng District of Beijing. Qi Zilai, the granddaughter of Qi Baishi, still lives in the same room in the northwest corner of the courtyard where she was born. One day in 1942, her mother felt birth pangs right after her grandparents and father left, leaving only herself and an aunt at home. A midwife was quickly sent for, and by the time the grandparents had returned, the Qi family had a new granddaughter. The loud cry of the newborn baby brought indescribeable happiness to Qi Baishi, and he named her Zilai ("self-inviting") to express his fondness for this impatient

  3. Dolphin QiQi Is Gone, but Research Will Continue

    Institute of Scientific and Technical Information of China (English)

    Guo Haiyan

    2002-01-01

    @@ The world's only captive Yangtze River dolphin, QiQi,died on July 14 at the Wuhan-based Institute of Hydrobiology (IHB) of the Chinese Academy of Sciences (CAS). At age of about 25, well advanced in years for a freshwater dolphin, his death is considered as a natural one.

  4. Free Flow of Qi in Conception Vessel and Governor Vessel Leading to Longevity

    Institute of Scientific and Technical Information of China (English)

    GUI Liang; CUI Yi-jun

    2003-01-01

    @@ Circle of Qi in human body, is namely Conception Vessel and Governor Vessel. It is divided into Large and Small Circle of qi. Small Circle of qi means that qi flows along the Circle of qi. Large Circle of qi means that vitality flows along the Circle of qi.Health-preserving expert holds that, if someone can achieve the skill of Small Circle of qi, he can return to juvenscence in essence, consolidating the body and achieve longevity.

  5. Tai Chi, Qi Gong and Reiki.

    Science.gov (United States)

    Chu, Dennis A

    2004-11-01

    Tai Chi, Qi Gong, and Reiki are complementary therapies that are gaining popularity with patients. Although these therapies seem simple and attractive in their philosophy and are easy to apply,more objective, well-designed research is needed to prove their efficacy and to gain acceptance from the medical community.

  6. Thermography applied acupuncture and qi-gong

    Science.gov (United States)

    Qin, Yuwen; Ji, Hong-Wei; Chen, Jin-Long; Li, Hong-Qi

    1997-04-01

    Thermographic technique can be used to measure temperature distribution of body surface in real-time, non-contact and full-field, which has been successfully used in medical diagnosis, remote sensing, and NDT, etc. The authors have developed a thermographic experiment that can be applied to inspect the effect of action of acupuncture and qi-gong (a system of deep breathing exercises) by measuring the temperature of hand and arm. The observation is performed respectively by thermography for the dynamic changes of temperature of the arm and hand after acupuncture therapy and qi-gong therapy. Thermographic results show that the temperature on the collateral channels increases markedly. In the meantime, it can be seen that the above therapies of Chinese medicine can stimulate the channel collateral system. This also contributes a new basis to the effect of action of the therapies of Chinese medicine. The work shows that thermographic technique is a powerful tool for research in Chinese medicine. In this paper, some thermal images are obtained from the persons treated with acupuncture and qi- gong.

  7. The sociology of Qi Gong: a qualitative study.

    Science.gov (United States)

    Posadzki, Paul

    2010-04-01

    This paper presents an in-depth, idiographic study of how individuals experience others during Qi Gong practice. Semi-structured interviews were conducted with three Qi Gong groups to collect research data. These data were transcribed verbatim and subjected to content and thematic analysis across and within groups. The analysis indicates extraordinary experiences of Qi Gong practitioners at various levels of their social functioning. Qi Gong influences their social health in complex and \\dimensional ways. The author compares and contrasts his results with those of recent research. Implications for practice are briefly outlined and possible strategies for future research are presented.

  8. 78 FR 43857 - Order Relating to Yaming Nina Qi Hanson

    Science.gov (United States)

    2013-07-22

    ... Province, People's Republic of China (``Qi Hanson''), of its intention to initiate an administrative... old university classmates in China provided her with $75,000 to purchase the autopilots from the... money to finance the entire purchase. In so doing, Qi Hanson committed one violation of section...

  9. [The application of qi-gong therapy to health care].

    Science.gov (United States)

    Li, Tso-Ying; Yeh, Mei-Ling

    2005-06-01

    A great number of clinical studies merging traditional Chinese medicine (TCM) and Western medicine have proved the complementary healing effects of qi-gong in medical science. Traditional Chinese respiration exercises help to regulate our mind, body and breathing and coordinate our internal organs, remove toxins and enhance immunity. Domestic and foreign studies indicate that qi-gong can relieve chronic pain, reduce tension, increase activities of phagocytes in coenocytes, improve cardiopulmonary function, improve eyesight, influence the index of blood biochemistry, etc. Due to the obvious healing effects of qi-qong therapy, through introducing qi-gone concepts and related medical research, this paper aims to inspire health care workers to integrate qi-qong therapy into medical treatments and nursing care, or to carry out further studies in order to make good the shortfall in provision of holistic medicine and nursing in the interests of the quality of patient care.

  10. Qi Baishi: A Legend in Contemporary Art History

    Institute of Scientific and Technical Information of China (English)

    Li Zhen

    2011-01-01

    Qi Baishi has become a legend in the history of world culture.He is an artist with the most outstanding Chinese art spirit and charisma since the 20th century.His art is under the space and time background which has a junction between ancient and modern.Qi Baishi's art roots in his nation,whereas it belongs to the whole world.The whole life of Qi Baishi was full of hardship and adversities.When he was young,Qi Baishi made his living by painting and worked hard on art.He even stopped selling his painting and refused to take the enemy's supply while Beijing was occupied.After the People's Republic of China was founded,he donated his works to the people and stuck to his way of loneliness in his whole life.His diligence and simplicity make him a master of art and life.

  11. Acupuncture De-qi: From Characterization to Underlying Mechanism

    Directory of Open Access Journals (Sweden)

    Shi-Peng Zhu

    2013-01-01

    Full Text Available De-qi refers to the participant’s subjective sensations and objective body responses as well as the acupuncturist’s perceptions while the acupuncturist needles certain acupoints in the participant’s body. In recent years, De-qi is getting increasing attention of the researchers and many efforts have been made to understand its mechanism. By the broad literature survey, this paper explores the subjective De-qi sensation of the patients, its influencing factors, and the resulting physiological responses. The purpose of this paper is expected to find out a possible mechanism of De-qi and to provide certain scientific evidence for acupuncture fundamental research and clinical practice.

  12. La energía vital-Qi

    OpenAIRE

    Coba Carrión, José Luis

    2013-01-01

    La Medicina Tradicional China (MTC en adelante), contempla algo que en la mirada positivista (de algunas comunidades de occidente), ha pasado completamente inadvertido, el Qi (se pronuncia chi). Para la MTC todo cuanto hay en el universo es Qi, tanto la corriente de bioelectricidad que constituye el cuerpo, la estructura material de un hueso o de otros tejidos o las emociones que generan pensamientos/sentimientos.

  13. Cell scientist to watch - Lei Stanley Qi.

    Science.gov (United States)

    Bobrowska, Anna

    2016-01-15

    Originally from China, Lei (Stanley) Qi obtained his first degree in physics and mathematics at the Tsinghua University. He then moved to University of California, Berkeley, where he graduated with an MA in physics and worked in the laboratory of Steven Chu, Noble Laureate in Physics (1997), before switching fields to pursue a PhD in bioengineering in the laboratories of Adam Arkin and Jennifer Doudna. Stanley's work earned him the National Institutes of Health Director's Early Independence Award, which allowed him to start his own laboratory at the University of California, San Francisco, as a Systems Biology Fellow without a postdoctoral training period. In 2014, he moved to Stanford, where he is now Assistant Professor at the Department of Bioengineering and of Chemical and Systems Biology, and is affiliated with Stanford Chemistry, Engineering and Medicine for Human Health (ChEM-H). He invented the use of the CRISPR-dCas9 system for transcriptional modulation and genome imaging. His current research is focused on developing new tools and technologies for genome editing and transcriptional modulation, manipulating molecular networks to understand fundamental principles of biology and engineering cells to exhibit desired behaviors, such as teaching immune cells to recognise and eliminate cancers.

  14. Study on meridians and collaterals through ying-qi and wei-qi%体验营卫论经脉

    Institute of Scientific and Technical Information of China (English)

    卓廉士

    2011-01-01

    Assisted with inference, and approved by the ancient medical classics, it is concluded that meridians and collaterals are often felt in the form of qi through imitation of the methods of life experiencing of the ancient people. Ying-qi is considered as jing-qi (meridian qi), which originates from the experiences of respiration. And wei-qi relates with experiences of sleep. Part of meridian theory originated from the traditional Chinese thought of seeking the internal cause but not the external manifestations, and paying attention to the self-adjustment, accomplishment and comprehension. It is also believed that the theory of ying-qi traveling inside the meridians and wei-qi outside the meridians is based on the theory that needling sensation has close relationship with wei-qi.%效仿古人采用的体验、感受生命的方法,辅以推理,证之以古代医学典籍,结果认为经脉常以气的形式被感受到.营气即经气,它源于对呼吸的体验,而卫气则与感受睡眠有关.经脉理论部分来自于中国传统的求诸内而不求诸外、重视生命修为和感悟的思维形式."营在脉中,卫在脉外"的理论建立在针刺"得气"来自卫气的基础之上.

  15. 朱琪%Zhu Qi

    Institute of Scientific and Technical Information of China (English)

    阳慧

    2014-01-01

    朱琪,1935年生,原卫生部中国健康教育研究所研究员,历任行为教育、疾病预防、性病艾滋病预防教育研究室主任。1980年代后期,因致力于艾滋病预防教育而进入性学研究领域,着重性道德教育研究。曾任卫生部艾滋病专家咨询委员会委员、中国性学会秘书长、副理事长、《中国性科学》杂志主编、北京心理卫生协会副理事长等。现任北大医学部性学研究中心研究员。%Zhu Qi,born in 1935,a researcher at the China Institute of Health Education of the former Min-istry of Health,served as the office director of behavioral education,disease prevention and AIDS prevention educa-tion.Dedicated AIDS prevention education,he set foot in the field of sexology research in the late 1980s,focusing on sexual morality education.He once severed as a committee member of the former Ministry of Health AIDS Expert Advisory Committee,Secretary -General and Vice Chairman of the China Sexology Association and chief editor of the Chinese Journal of Human Sexuality and vice president of Beijing Mental Health Association.He is now a re-search in the Sexology Research Center of Peking University Health Service Center.

  16. Parental use of the term "Hot Qi" to describe symptoms in their children in Hong Kong: a cross sectional survey "Hot Qi" in children

    Directory of Open Access Journals (Sweden)

    Chan Danny

    2006-01-01

    Full Text Available Abstract Background The Chinese term "Hot Qi" is often used by parents to describe symptoms in their children. The current study was carried out to estimate the prevalence of using the Chinese term "Hot Qi" to describe symptoms in children by their parents and the symptomatology of "Hot Qi". Method A cross sectional survey by face-to-face interview with a semi-structured questionnaire was carried out in a public hospital and a private clinic in Hong Kong. The parental use of the term "Hot Qi", the symptoms of "Hot Qi" and the remedies used for "Hot Qi" were asked. Results 1060 pairs of children and parents were interviewed. 903 (85.1% of parents claimed that they had employed the term "Hot Qi" to describe their children's symptoms. Age of children and place of birth of parents were the predictors of parents using the term "Hot Qi". Eye discharge (37.2%, sore throat (33.9%, halitosis(32.8%, constipation(31.0%, and irritable (21.2% were the top five symptoms of "Hot Qi" in children. The top five remedies for "Hot Qi" were the increased consumption of water (86.8%, fruit (72.5%, soup (70.5%, and the use of herbal beverages "five-flower- tea" (a combination of several flowers such as Chrysanthemum morifolii, Lonicera japonica, Bombax malabaricum, Sophora japonica, and Plumeria rubra (57.6% or selfheal fruit spike (Prunella vulgaris (42.4%. Conclusion "Hot Qi" is often used by Chinese parents to describe symptoms in their children in Hong Kong. Place of birth of parents and age of the children are main factors for parents to apply the term "Hot Qi" to describe symptoms of their children. The common symptoms of "Hot Qi" suggest infections or allergy.

  17. Application of Bu Zhong Yi Qi Tang According to TCM Differentiation of Syndromes

    Institute of Scientific and Technical Information of China (English)

    谢甦

    2002-01-01

    @@ Bu Zhong Yi Qi Tang (补中益气汤Decoction for Reinforcing the Middle-jiao and Replenishing Qi) is an effective formulated recipe commonly used for treating a variety of diseases with the manifestations of kidney-qi deficiency. In my opinion, however, it is also very effective for the conditions of which the symptoms of kidney-qi deficiency is not noticeable, but its mechanism lies in dysfunction of the spleen. The following are some examples.

  18. A poetica e a pratica do Qi Gong dos Simbolos

    OpenAIRE

    Milena Machado Figueiredo

    2000-01-01

    Resumo: A criação deum vídeo sobre uma prática corporal chinesa denominada Qi Gong (1) dos Símbolos é o tema deste projeto, no qual se procurou explorar as possíveis relações entre movimentos corporaisdo oriente e o meio vídeo. O conteúdo estético da obraem vídeo resultou da investigação do tempo interno e do conteúdo simbólico da prática corporal, que compuseram uma expressão audiovisual própria baseada na filosofia chinesa e na pesquisa de cada movimento que compõe o Qi Gong dos S...

  19. Zhang Qi's Experience in Treating Chronic Renal Failure

    Institute of Scientific and Technical Information of China (English)

    LIN Qi-zhan; XU Da-ji; MA Yu-peng

    2008-01-01

    @@ Chronic renal failure is a result of the parenchymatous injury of kidney and progressive exacerbation due to many reasons.It is a svstematic clinical syndrome caused by the disturbance in excreting metabolites,adjusting water-electrolyte and acid-base balance as well as production and inactivation of active substances of endocrine.Prof Zhang Qi has rich clinical experience in treating renal failure.A report follows.

  20. Acupuncture phenomenon of the Qi energy complete awakening

    Directory of Open Access Journals (Sweden)

    Viktor N. Skakov

    2013-11-01

    Full Text Available Aims The aim is to study the phenomenon of the Qi energy complete awakening using the acupuncture method and the reactions appearing during this process that lead to recovery of the body and of the cardiovascular system first of all. Materials and methods The study is based on the classical acupuncture method using the unique technique of effecting the points by I-Ching. Results The result is the body recovering the pathologic diseases the patient has been suffering for decades. Conclusion The new method for acupuncture is the Qi energy complete awakening based on structuring the Qi energy in the acupoints according to the figures of gua (trigrams and hexagrams in the Chinese Canon of Changes and can be used for the treatment of almost any kind of the disease including cardiovascular. The given method allows not only balancing the Yin and Yang energy in the human body but also launching the generalized recovery program concentrated in the deepest layers of the human genetic memory. The given method allows treating many diseases considered to be incurable by the official medicine.

  1. Dr.LI Bo-jian's Experience in Treating Dermatoses by Means of Qi-Invigorating

    Institute of Scientific and Technical Information of China (English)

    RONG Xian-hui

    2009-01-01

    @@ Qi-invigorating is a method used for treating qi-deficiency syndromes. Qi-deficiency is mostly related with the internal organs of the hmg and spleen.Qi of the human body originates from the middle energizer and is dominated by the lung. It defends the superficial part of the body exteriorly, connects with the blood vessels interiorly, and keeps circulating in terms of ascending, descending, coming in and going out. Since the lung dominates the skin and hair, and the spleen dominates the four limbs, the lung and spleen are closely related with the skin diseases.

  2. Measuring quality improvement in public health: the development and psychometric testing of a QI Maturity Tool.

    Science.gov (United States)

    Joly, Brenda M; Booth, Maureen; Mittal, Prashant; Shaler, George

    2012-06-01

    There is growing interest and investment in improving the quality of public health services and outcomes. Following the lead of other sectors, efforts are underway to introduce systematic quality improvement (QI) tools and approaches to state and local public health agencies. Little is known, however, about how to describe and reliably measure the level of QI maturity within a public health agency. The authors describe the development of a QI Maturity Tool using research from the fields of organizational design, psychology, health care, and complexity theory. The 37-item assessment tool is based on four quality domains derived from the literature: (a) organizational culture, (b) capacity and competency, (c) practice, and (d) alignment and spread. The tool was designed to identify features of an organization that may be enhancing or impeding QI; monitor the impact of efforts to create a more favorable environment for QI; and define potential cohorts of public health agencies for evaluation purposes. The article presents initial steps in testing and validating the QI Maturity Tool including: (a) developing a theoretical framework, (b) assuring face and content validity, (c) determining the tool's reliability based on estimates of internal consistency, (d) assessing the dimensionality, and (f) determining the construct validity of the instrument. The authors conclude that there is preliminary evidence that the QI Maturity Tool is a promising instrument. Further work is underway to explore whether self-reported survey results align with an agency's actions and the products of their QI efforts.

  3. Two genes conferring resistance to Pythium stalk rot in maize inbred line Qi319.

    Science.gov (United States)

    Song, Feng-Jing; Xiao, Ming-Gang; Duan, Can-Xing; Li, Hong-Jie; Zhu, Zhen-Dong; Liu, Bao-Tao; Sun, Su-Li; Wu, Xiao-Fei; Wang, Xiao-Ming

    2015-08-01

    Stalk rots are destructive diseases in maize around the world, and are most often caused by the pathogen Pythium, Fusarium and other fungi. The most efficient management for controlling stalk rots is to breed resistant cultivars. Pythium stalk rot can cause serious yield loss on maize, and to find the resistance genes from the existing germplasm is the basis to develop Pythium-resistance hybrid lines. In this study, we investigated the genetic resistance to Pythium stalk rot in inbred line Qi319 using F2 and F2:3 population, and found that the resistance to Pythium inflatum in Qi319 was conferred by two independently inherited dominant genes, RpiQI319-1 and RpiQI319-2. Linkage analysis uncovered that the RpiQI319-1 co-segregated with markers bnlg1203, and bnlg2057 on chromosome 1, and that the RpiQI319-2 locus co-segregated with markers umc2069 and bnlg1716 on chromosome 10. The RpiQI319-1 locus was further mapped into a ~500-kb interval flanked by markers SSRZ33 and SSRZ47. These results will facilitate marker-assisted selection of Pythium stalk rot-resistant cultivars in maize breeding. To our knowledge, this is the first report on the resistance to P. inflatum in the inbred line Qi319, and is also the first description of two independently inherited dominant genes conferring the resistance of Pythium stalk rot in maize.

  4. [Professor GAO Yuchun's experience on "sequential acupuncture leads to smooth movement of qi"].

    Science.gov (United States)

    Wang, Yanjun; Xing, Xiao; Cui, Linhua

    2016-01-01

    Professor GAO Yuchun is considered as the key successor of GAO's academic school of acupuncture and moxibustion in Yanzhao region. Professor GAO's clinical experience of, "sequential acupuncture" is introduced in details in this article. In Professor GAO's opinions, appropriate acupuncture sequence is the key to satisfactory clinical effects during treatment. Based on different acupoints, sequential acupuncture can achieve the aim of qi following needles and needles leading qi; based on different symptoms, sequential acupuncture can regulate qi movement; based on different body positions, sequential acupuncture can harmonize qi-blood and reinforcing deficiency and reducing excess. In all, according to the differences of disease condition and constitution, based on the accurate acupoint selection and appropriate manipulation, it is essential to capture the nature of diseases and make the order of acupuncture, which can achieve the aim of regulating qi movement and reinforcing deficiency and reducing excess.

  5. [Brief analysis on Tang Zong-hai's view about qi transformation in channels ].

    Science.gov (United States)

    Li, Su-yun; Zhao, Jing-sheng

    2009-05-01

    This present paper interprets and analyzes the connotation of qi transformation in Tang Zong-hai's idea of channels in the Qing Dynasty. During the middle and late periods of the Qing Dynasty, western medicine was introduced into China on a large scale, starting with "Channels being the qi transformation pathway of viscera" clearly raised in Essence of Medical Classics on the Confluence of Chinese and Western Medicine written by Tang Zong-hai, and in combination with relevant discussion of physicians of successive dynasties on channels, qi information and others, it was revealed that the connotation of channels expounded by Tang Zong-hai with qi transformation view is of a certain rationality, and it was further realized that the concept of "channels" in traditional twelve meridians theory indeed contains some thought source of qi information theory of traditional Chinese medicine.

  6. What Influences Participation in QI? A Randomized Trial of Addiction Treatment Organizations.

    Science.gov (United States)

    Grazier, Kyle L; Quanbeck, Andrew R; Oruongo, John; Robinson, James; Ford, James H; McCarty, Dennis; Pulvermacher, Alice; Johnson, Roberta A; Gustafson, David H

    2015-01-01

    Healthcare providers have increased the use of quality improvement (QI) techniques, but organizational variables that affect QI uptake and implementation warrant further exploration. This study investigates organizational characteristics associated with clinics that enroll and participate over time in QI. The Network for the Improvement of Addiction Treatment (NIATx) conducted a large cluster-randomized trial of outpatient addiction treatment clinics, called NIATx 200, which randomized clinics to one of four QI implementation strategies: (1) interest circle calls, (2) coaching, (3) learning sessions, and (4) the combination of all three components. Data on organizational culture and structure were collected before, after randomization, and during the 18-month intervention. Using univariate descriptive analyses and regression techniques, the study identified two significant differences between clinics that enrolled in the QI study (n = 201) versus those that did not (n = 447). Larger programs were more likely to enroll and clinics serving more African Americans were less likely to enroll. Once enrolled, higher rates of QI participation were associated with clinics' not having a hospital affiliation, being privately owned, and having staff who perceived management support for QI. The study discusses lessons for the field and future research needs.

  7. [Discussion on "removing stasis and regulating qi and blood" in the scraping therapy].

    Science.gov (United States)

    Wu, Song; Liang, Zhong

    2016-04-01

    Stasis is the critical causative factor and pathological production considered in clinic treatment. Promoting the circulation in blood vessel and removing stasis are equally important in treatment. Stasis is interactive with qi and blood. Removing stasis aims to regulating the circulation of qi and blood. Scraping therapy is one of the major approaches to stasis removal in TCM. In clinical practice, the stasis can be removed with scraping, bleeding and cupping, etc. Additionally, removing stasis with scraping should be combined with regulating qi and blood to enhance the therapeutic effect.

  8. [Study on the biofeedback effect and significance of getting qi in acupuncture].

    Science.gov (United States)

    Gu, Zhong-yue; Ma, Tie-ming

    2009-05-01

    In this paper, the basic concept of biofeedback therapy and the relationship between getting qi in acupuncture and biofeedback are introduced. Getting qi in acupuncture as a controllable index of biological information feedback between the physician and the patient, meets the requirement of technique manipulation for biofeedback therapy. Arrival of qi has double regulative effects on the psychological and physiological functions of the patient, and has the effectiveness of the language suggestion and behavior suggestion in correcting the error in cognition of the patient. To take getting qi as an index in treatment of mental disorders conforms to theories of traditional Chinese medicine and is supported by modern medical research achievements, enriching contents and ways of biofeedback therapy and facilitating the development of acupuncture medicine towards biological-psychological-social medicine model.

  9. Tai Chi and Qi Gong for Health and Well-Being

    Medline Plus

    Full Text Available ... Legislation Advisory Council Job Opportunities All About NCCIH Health Topics A-Z # A B C D E ... Y Z Tai Chi and Qi Gong for Health and Well-Being Share: © Mariann Seriff The following ...

  10. [Discussion on needling sensation, arrival of qi and needling response (Deqi)].

    Science.gov (United States)

    Zhang, Fang; Wang, Hong-Du

    2012-12-01

    The current appointed teaching material of Science of Acupuncture and Moxibustion holds that there is no difference among the needling sensation, arrival of qi and needling response. However, the author has a different understanding. Therefore, Neijing (Internal Classic), its annotation, exposition and understandings of ancient and modern famous experts are cited to analyze their meanings. And the result indicates that the needling sensation is subjective feelings and perceived responses of doctors and patients. Arrival of qi is the healing process of the organ through activating the anti-pathogenic qi to expel the pathogens. The needling response is the final aim of acupuncture therapy. Thus, the meaning of needling sensation, arrival of qi, and needling response are different. And an accurate understanding can better guide acupuncture treatment.

  11. Yang/Qi Invigoration: An Herbal Therapy for Chronic Fatigue Syndrome with Yang Deficiency?

    Directory of Open Access Journals (Sweden)

    Pou Kuan Leong

    2015-01-01

    Full Text Available According to traditional Chinese medicine (TCM theory, Yang and Qi are driving forces of biological activities in the human body. Based on the crucial role of the mitochondrion in energy metabolism, we propose an extended view of Yang and Qi in the context of mitochondrion-driven cellular and body function. It is of interest that the clinical manifestations of Yang/Qi deficiencies in TCM resemble those of chronic fatigue syndrome in Western medicine, which is pathologically associated with mitochondrial dysfunction. By virtue of their ability to enhance mitochondrial function and its regulation, Yang- and Qi-invigorating tonic herbs, such as Cistanches Herba and Schisandrae Fructus, may therefore prove to be beneficial in the treatment of chronic fatigue syndrome with Yang deficiency.

  12. Technology for the production of Zero Q.I pitch from coal tar

    Science.gov (United States)

    Karthik, K.; Kumar, K. Rajesh; Rao, C. V. Nageswara; Kumar, B. Vinod; Murty, J. V. S.

    2013-06-01

    Zero Quinoline Insolubles (Q.I) pitch is a special type of pitch obtained from pre-treatment of coal tar, which is converted into pitch. This is used for impregnation of electrodes for improving the strength, electrical properties and also used as a pre-cursor for Mesophase pitch for producing Mesophase pitch based carbon fibers, carbon foam, and Meso carbon micro beads. This paper discusses the technology of Q.I separation from Coal Tar by using decantation of Coal Tar mixed with Heavy Creosote Oil (HC Oil) at different temperatures. By this method we were able to produce the Zero Q.I pitch with a Q.I value of 0.1%.

  13. Tai Chi and Qi Gong for Health and Well-Being

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    Full Text Available ... concentration, and reduce stress. and qi gong A component of traditional Chinese medicine that combines movement, meditation, ... more about tai chi NCCIH has provided this material for your information. It is not intended to ...

  14. Lumbar disc herniation treated with qi pathway intervention and spinal adjustment:a randomized controlled trial

    Institute of Scientific and Technical Information of China (English)

    杨军雄

    2013-01-01

    Objective To compare the efficacy difference in the treatment of lumbar disc herniation(LDH)between the comprehensive therapy of Qi pathway intervention and the spinal adjustment and the conventional therapy of acupuncture and Tuina and explore the analgesic mechanism

  15. [Application of "regulating spirit and conducting qi" therapy in treatment of psychological diseases].

    Science.gov (United States)

    Chen, Li-zhi; Wang, Ling-ling

    2011-11-01

    Taking the clinical curative effects of psychological diseases treated with "regulating spirit and conducting qi" therapy as the starting point, the manipulation and technology method of "regulating spirit and conducting qi" therapy are introduced in the paper. Based on analysis of "conducting qi" therapy of Neijing (Internal Classic), it is summarized that, in "regulating spirit and conducting qi" therapy, tardiness and tenderness are taken as technical core of manipulation, individualization of patients is taken as basis, and regulation on spirit as key issue of technology, so as to rapidly, effectively and safely regulate the functional status of emotion and organism. It is aq effective technology method for treating psychological diseases, especially for insomnia, anxiety and somatic symptoms, with better curative effects.

  16. Tai Chi and Qi Gong for Health and Well-Being

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    Full Text Available ... All Health Information Research Research Results Results by Date Sponsored by NCCIH Division of Extramural Research Conducted ... and Well-Being Video Introduction and Background Warm-up Qi Gong Tai Chi Cool Down This page ...

  17. [Is Qi Gong suitable for the prevention of low back pain?].

    Science.gov (United States)

    Zauner-Dungl, Andrea

    2004-12-01

    Low back pain is one of the main problems of health care, and has many causes. To prevent low back pain daily activities are highly important--static work as well as dynamic movement--carried out in an ergonomic and economical way. Studies have shown that the compliance of patients with regard to exercise training and ergonomic recommendations is not very high. The main posture of Qi Gong training is similar to the recommended posture by low back schools. Qi gong exercises respect basic physiological and ergonomic principles of movement in every way. Qi Gong fulfils the most important criteria for the prevention and therapy of idiopathic low back pain. Qi Gong training requires no special equipment. It is simple and can be undertaken everywhere. A growing number of people have become interested in Qi Gong, and train regularly and effectively. Low back pain rarely occurs in such people, and therefore Qi Gong should be considered as one of the most effective means of prevention.

  18. Feasibility of a virtual learning collaborative to implement an obesity QI project in 29 pediatric practices.

    Science.gov (United States)

    John, Tamara; Morton, Michaela; Weissman, Mark; O'Brien, Ellen; Hamburger, Ellen; Hancock, Yolandra; Moon, Rachel Y

    2014-04-01

    Quality improvement (QI) activities are required to maintain board certification in pediatrics. However, because of lack of training and resources, pediatricians may feel overwhelmed by the need to implement QI activities. Pediatricians also face challenges when caring for overweight and obese children. To create a virtual (online) QI learning collaborative through which pediatric practices could easily develop and implement a continuous QI process. Prospective cohort. Pediatric practices that were part of the Children's National Health Network were invited to participate, with the option to receive continuing medical education and maintenance of certification credits. s) Practices conducted baseline and monthly chart audits, participated in educational webinars and selected monthly practice changes, using Plan-Do-Study-Act cycles. Practices reported activities monthly and periodic feedback was provided to practices about their performance. s) Improvement in (i) body mass index (BMI) percentile documentation, (ii) appropriate nutritional and activity counseling and (iii) follow-up management for high-risk patients. Twenty-nine practices (120 providers) participated, and 24 practices completed all program activities. Monthly chart audits demonstrated continuous improvement in documentation of BMI, abnormal weight diagnosis, nutrition and activity screening and counseling, weight-related health messages and follow-up management of overweight and obese patients. Impact of QI activities on visit duration and practice efficiency was minimal. A virtual learning collaborative was successful in providing a framework for pediatricians to implement a continuous QI process and achieve practice improvements. This format can be utilized to address multiple health issues.

  19. Variety regulation research of the Anthraquinone in San Cheng Qi Tang compound prescribe compatibility of medicines

    Institute of Scientific and Technical Information of China (English)

    SUN Zhao-shu; ZHANG Zhen-qiu; YUAN Chang-lu

    2005-01-01

    The purpose is to research compound prescribe compatibility of medicines have some influence on anthraquinone which is the gentleman medicine CRC's valid composition dissolution rate in San Cheng Qi Tang. The method. Adopting respectively RP - HPLC and colorimetric method, measure the content of liberation3 methylchrysazin and 3 - methylchrysazin and combined 3 - methylchrysazin and 3 - methylchrysazin total liberation anthraquinone and total combined anthraquinone in the different decoction water liquid coming from single CRC the different decoction and compatibility of medicines method of San Cheng Qi Tang. The result: Compared with CRC single flavor decoction water, liberation anthraquinone and combined anthraquinone content show differently in the most decoction water liquid, Combined 3 - methylchrysazin and combined anthraquinone content in decoction prescribe as follows in proper order decrease:Da Cheng Qi Tang > Xiao San Cheng Qi Tang > Tiao Wei Cheng Qi Tang. The conclusion: Because CRC mate with different medicine material . different decoction method, liberation anthraquinone and combined anthraquinone content in San Cheng Qi Tang change. The combined 3 methylchrysazin and combined anthraquinon content variety order in accordance with its decanta bottom function.

  20. What Is the de-qi-Related Pattern of BOLD Responses? A Review of Acupuncture Studies in fMRI

    Directory of Open Access Journals (Sweden)

    Jinbo Sun

    2013-01-01

    Full Text Available de-qi, comprising mostly subjective sensations during acupuncture, is traditionally considered as a very important component for the possible therapeutic effects of acupuncture. However, the neural correlates of de-qi are still unclear. In this paper, we reviewed previous fMRI studies from the viewpoint of the neural responses of de-qi. We searched on Pubmed and identified 111 papers. Fourteen studies distinguishing de-qi and sharp pain and eight studies with the mixed sensations were included in further discussions. We found that the blood oxygenation level-dependent (BOLD responses associated with de-qi were activation dominated, mainly around cortical areas relevant to the processing of somatosensory or pain signals. More intense and extensive activations were shown for the mixed sensations. Specific activations of sharp pain were also shown. Similar BOLD response patterns between de-qi evoked by acupuncture stimulation and de-qi-like sensations evoked by deep pain stimulation were shown. We reckon that a standardized method of qualification and quantification of de-qi, deeper understanding of grouping strategy of de-qi and sharp pain, and making deep pain stimulation as a control, as well as a series of improvements in the statistical method, are crucial factors for revealing the neural correlates of de-qi and neural mechanisms of acupuncture.

  1. The Eruption of the Candidate Young Star ASASSN-15qi

    CERN Document Server

    Herczeg, Gregory J; Shappee, Benjamin J; Chen, Ping; Hillenbrand, Lynne A; Jose, Jessy; Kochanek, Christopher S; Prieto, Jose L; Stanek, K Z; Kaplan, Kyle; Holoein, Thomas W -S; Mairs, Steve; Johnstone, Doug; Gully-Santiago, Michael; Zhu, Zhaohuan; Smith, Martin C; Bersier, David; Mulders, Gijs D; Filippenko, Alexei V; Ayani, Kazuya; Brimacombe, Joseph; Brown, Jonathan S; Connelley, Michael; Harmanen, Jussi; Ito, Ryosuke; Kawabata, Koji S; Maehara, Hiroyuki; Takata, Koji; Yuk, Heechan; Zheng, WeiKang

    2016-01-01

    Outbursts on young stars are usually interpreted as accretion bursts caused by instabilities in the disk or the star-disk connection. However, some protostellar outbursts may not fit into this framework. In this paper, we analyze optical and near-infrared spectra and photometry to characterize the 2015 outburst of the probable young star ASASSN-15qi. The $\\sim 3.5$ mag brightening in the $V$ band was sudden, with an unresolved rise time of less than one day. The outburst decayed exponentially by 1 mag for 6 days and then gradually back to the pre-outburst level after 200 days. The outburst is dominated by emission from $\\sim10,000$ K gas. An explosive release of energy accelerated matter from the star in all directions, seen in a spectacular cool, spherical wind with a maximum velocity of 1000 km/s. The wind and hot gas both disappeared as the outburst faded and the source the source returned to its quiescent F-star spectrum. Nebulosity near the star brightened with a delay of 10-20 days. Fluorescent excitati...

  2. Qing-Qi Rickshaw : A Boon Or Bane For Public Transportation? A Study Of Road Traffic Injury Patterns Involving Qing-Qi Rickshaws In Karachi Pakistan.

    Science.gov (United States)

    Muzzammil, Muhammad; Minhas, Muhammad Saeed; Effendi, Jahanzeb; Jahanzeb, Syed; Mughal, Ayesha; Qadir, Abdul

    2017-01-01

    The three-wheeler Qing-qi and Compressed Natural Gas (CNG) auto-rickshaws were introduced in Karachi to meet the transportation demand of the growing population. These vehicles have directly or indirectly been implicated in a number of road traffic violations as well as road accidents. This study aims to describe the crash characteristics and injury patterns for Qing-qi rickshaw occupants and other road users hit by Qing-qi rickshaw in Karachi, Pakistan. An Observational/ Descriptive study was conducted at Accident & Emergency and Orthopaedic Surgery Department, Jinnah Post Graduate Medical Centre, Karachi Pakistan from July 2014 to June 2015.All patients who came with Qing-qi rickshaw accident in Accident & Emergency (A&E) of JPMC were included. Crash characteristics, details of injuries, injury severity parameters and outcome were documented in detailed interviews. Four hundred and eighty-six rickshaw related injuries were noted in road traffic accidents by Qing-gi rickshaw. Age range was 2-85 (43.5±58.68). 350 injured victims were males and 136 were females. By occupation most victims were laborers and daily wage workers (45%) and students (21%). Overloading of vehicle with more than two passengers was found in (28.5%). The most common cause of injury was collision with a moving vehicle (56%), followed by fall from rickshaw. The most common contributing factor was the overloading of rickshaw and roll over on turning (61%). Injury severity on arrival were mild (49%), moderate were (32%), and severe were (19%). Injuries related to head and neck (26%), face (14%), thorax and abdomen (5%), lower extremity and pelvic girdle (31%) and upper extremity (23%) were observed. Qing-qi rickshaw injuries are common and these vehicles are vulnerable to road traffic accidents. Occupants and road users are both at risk of injuries.

  3. More than DeQi: Spatial Patterns of Acupuncture-Induced Bodily Sensations.

    Science.gov (United States)

    Jung, Won-Mo; Shim, Woosun; Lee, Taehyung; Park, Hi-Joon; Ryu, Yeonhee; Beissner, Florian; Chae, Younbyoung

    2016-01-01

    Acupuncture uses needles to stimulate certain parts of the body, inducing a specific sensation, termed DeQi, which regard as essential for acupuncture's therapeutic effect. Here, we used the newly developed tool, bodily sensation mapping, to investigate the spatial configuration of acupuncture-induced sensations throughout the body. Twenty-five participants randomly received acupuncture stimulation or tactile stimulation using a von Frey filament at four different acupoints (HT7, PC6, ST36, and SP10) on the left side of the body. Subjects evaluated the characteristics of DeQi sensations and marked the areas of induced sensations on a body outline. We compared the psychophysical responses of DeQi sensations and visualized the spatial patterns of these sensations using statistical parametric mapping. We found greater intensity of DeQi sensations following acupuncture stimulation compared with tactile stimulation, with relatively small differences among the four acupoints. The sensation maps exhibited similar spatial patterns for acupuncture and tactile stimulation in the areas close to the stimulated sites. However, acupuncture was associated with additional sensations in areas remote from the stimulated sites. This study demonstrates that acupuncture stimulation produces greater DeQi sensations than tactile stimulation and results in the spreading of sensations to areas remote from the stimulus sites. Investigating the spatial patterns of acupuncture-induced sensations may be crucial for understanding the underlying mechanisms of acupuncture.

  4. More than DeQi: Spatial patterns of acupuncture-induced bodily sensations

    Directory of Open Access Journals (Sweden)

    Won-Mo Jung

    2016-10-01

    Full Text Available Acupuncture uses needles to stimulate certain parts of the body, inducing a specific sensation, termed DeQi, which many regard as essential for acupuncture's therapeutic effect. Here, we used the newly developed tool, bodily sensation mapping, to investigate the spatial configuration of acupuncture-induced sensations throughout the body. Twenty-five participants randomly received acupuncture stimulation or tactile stimulation using a von Frey filament at four different acuoints (HT7, PC6, ST36, and SP10 on the left side of the body. Subjects evaluated the characteristics of DeQi sensations and marked the areas of induced sensations on a body outline. We compared the psychophysical responses of DeQi sensations and visualized the spatial patterns of these sensations using statistical parametric mapping. We found greater intensity of DeQi sensations following acupuncture stimulation compared with tactile stimulation, with relatively small differences among the four acupoints. The sensation maps exhibited similar spatial patterns for acupuncture and tactile stimulation in the areas close to the stimulated sites. However, acupuncture was associated with additional sensations in areas remote from the stimulated sites. This study demonstrates that acupuncture stimulation produces greater DeQi sensations than tactile stimulation and results in the spreading of sensations to areas remote from the stimulus sites. Investigating the spatial patterns of acupuncture-induced sensations may be crucial for understanding the underlying mechanisms of acupuncture.

  5. Evidence of Qi-gong energy and its biological effect on the enhancement of the phagocytic activity of human polymorphonuclear leukocytes.

    Science.gov (United States)

    Fukushima, M; Kataoka, T; Hamada, C; Matsumoto, M

    2001-01-01

    In order to test for an effect of phosphate buffered saline (PBS) treated externally with Qi energy ("Qi-treated" PBS) on the phagocytic activity of human polymorphonuclear leukocytes (PMNs), rigorously controlled experiments employing masking and randomized procedures were carried out under independent monitoring. In all experiments, Qi treatment was externally applied under monitoring to newly purchased unopened 100 ml bottles of PBS, and the PMN phagocytic activity was assayed by one experimenter in masked, randomized and monitored conditions using a highly sensitive chemiluminescence method. Phagocytic activity data were obtained in triplicate for each sample and then statistically analyzed. The PBS samples Qi-treated by the Qi-gong master and by one of the Qi-gong trainees showed clear stimulation of PMN phagocytic activity which was significant statistically, and this phenomenon was highly reproducible. Out of 10 experiments by the Qi-gong master, only twice did Qi-treatment fail to influence the PBS. The activity of Qi-treated PBS decayed over days or weeks. Furthermore, it was found that Qi-treated PBS had decreased phagocytic stimulatory activity after microwave treatment, but not after autoclave treatment. We also demonstrated that microwave irradiation and infrared laser pulse irradiation have similar effects on PBS as Qi-treatment. The results obtained in this experiment provide evidence of the existence of Qi energy, its ability to influence an electrolyte solution and its biological effect. Furthermore, microwave or infrared laser pulse treatment was found to partly mimic the Qi-treatment of PBS.

  6. “气”化太极论%On the"Qi"theory of Taijiquan

    Institute of Scientific and Technical Information of China (English)

    李晓乾; 王凤阳

    2013-01-01

    Taijiquan is a high level of qigong. The qi in it is subtle and variable. Practicing and making good use of this qi can bring great benefit to the exerciserS for their training ,health and wrestling skills. Therefore,qi should be paid great attention to by the shadow-boxers.%  太极拳是一门高层次的气功。太极之气精妙无穷,而练习并运用此气,对太极拳的修炼以及健身、技击作用巨大,应引起广大太极拳爱好者的高度重视。

  7. Qi Gong exercises and Feldenkrais method from the perspective of Gestalt concept and humanistic psychology.

    Science.gov (United States)

    Posadzki, Paul; Stöckl, Andrea; Mucha, Dariusz

    2010-07-01

    This study describes two similar approaches to human movement: Qi Gong exercises and the Feldenkrais method. These systems are investigated in terms of Gestalt concepts and humanistic psychology. Moshe Feldenkrais created the concept known as Awareness Through Movement. This concept assumes that by becoming more aware of one's movements, one functions at a higher level. In similar ways to those using the Feldenkrais method, individuals may become more aware of their own movements by performing Qi Gong exercises: A therapeutic modality that facilitates mind-body integration. Qi Gong exercises commonly lead to increased personal awareness accompained by enhanced quality, fluency and smoothness of movement. These two methods of movement therapies are explored in terms of their relations with Gestalt concept and humanistic psychology. (c) 2008. Published by Elsevier Ltd. All rights reserved.

  8. "Chi-Fang-Qi": Is it the aureole of an ancient supernova?

    Institute of Scientific and Technical Information of China (English)

    ZHAO Fuyuan; JIANG Shiyang

    2005-01-01

    An annotation for the statement about JingXing (Great Star) in the most famous Chinese ancient historical book Shi Ji (Historical Records) authored by Sima Qian reads as follows: "There was a red aureole ("Chi-Fang-Qi") which connected with a deep-color aureole ("Qing-Fang-Qi"). Two yellow stars were in the red aureole,one yellow star was in the deep-color aureole". The author of the annotation was Meng Kang, an officer as well as a scholar of the Wei State in the Three Kingdoms period. The same records are to be found in two other Chinese historical books compiled by the authors of later ages in Tang Dynasty --Jin History and Sui History. The scene illustrated by the record of "Chi-Fang-Qi" is very similar to the pictures of SN1987A taken by the Hubble Space Telescope. Let it be noted that although the ancient authors were often with serious wrong understandings of some astronomical phenomena such as supernovae, their depictions about natural phenomena they witnessed were mostly objective, and it was unlikely that they fictionally made the record of "Chi-Fang-Qi". We infer that the ancient observers might have ever watched a very bright supernova with an aureole structure in its remnant and then left such a record. Meng Kang perhaps was the first to give the record about "Chi-Fang-Qi", and he might have lived in the period from about AD 180 to AD250, very near to AD 185, so, here the supernova the ancient people watched was most likely the one in the year of AD 185. This supposition is consistent with the distance parameter of the most possible remnant of SN185 derived by some modern measurements. If the correlation between the record of "Chi-Fang-Qi" and the supernova remnant can be further proven true, it would be an important verification of the modern theory about stellarevolution.

  9. Discussion About Disease Syndrome of Qi and Blood and Body Fluid from the Viewpoint of Activities of Qi%从气化论气血津液病证

    Institute of Scientific and Technical Information of China (English)

    侯双双; 张瑜; 张美玉; 靳冬慧; 阚振棣; 鞠静; 庄园; 蒋璐; 杜武勋

    2016-01-01

    中医学从生理、病因、病理,到辨证、施治,无一不是以气化论为理论根据的,因此,气化论是中医理论体系的真正核心,中医理论本质是气化论.气化作用激发和协调着气、血、津液有形与无形之间的相互变化,维持着各个脏腑官窍的正常活动和机体的整个生命全过程.人体内气、血、津、液的产生、输布、发挥作用等,亦无不有赖于气化.气化有常,则津液流行,气血充盛,五脏安和,疾病不生;气化失常则津液不行,气血衰少,五脏动摇,变生百病;气体终止,则精气竭绝,阴阳离散.在临床上无论治疗气血病证,亦或是津液病证,调理气机、推动气化都是治疗的关键.%All the aspects from physiology,etiology and pathology to therapy based on syndrome differentiation regard theory of activities of qi as theoretical basis,so theory of activities of qi the real core of TCM theory system,and the essence of traditional Chinese medicine theory is theory of activities of qi.Activities of qi stimulate and coordinate the mutual changes between qi and blood and body fluid,maintain the normal activities of viscera and each office and the the body's whole life process.Production,distribution and function of qi and blood and body fluid all depend on activities of qi.The normal activities of qi can make body fluid move smoothly,qi and blood sufficient,the five zang-organs harmonize each other and healthy;Disorder of activities of qi lead to body fluid move unsmoothly,qi and blood insufficient,the five zang-organs in disharmony,and all kinds of diseases;The no movement of qi leads to exhausted essence,yin and yang to separate from each other.In clinical practice,whether treating syndrome of qi-blood disease or syndrome of body fluid,regulating and promoting qi activities are vital.

  10. Clinical Observation in 102 Cases of Chronic Pelvic Inflammation Treated with Qi Jie Granules

    Institute of Scientific and Technical Information of China (English)

    章勤; 何嘉琳; 何少山; 许萍

    2004-01-01

    Objective: To observe the therapeutic effects of Qi Jie Granule (芪竭颗粒) on chronic pelvic inflammation. Method: The therapeutic effect, T-lymphocytic subgroups and indexes of blood rheology were observed when 102 cases of chronic pelvic inflammation in the treatment group were treated with Qi Jie Granule, and another 70 cases were treated with Qian Jin Pian as the controls. Results: The total effective rate was 96.08% in the treatment group, but 84.29% in the control group with a significant difference between the two groups (P<0.01). Qi Jie Granule was also found effective in improving blood viscosity and regulating T-lymphocytic subgroups, and the difference before and after the treatment was also very significant (P<0.05 or P<0.01). Conclusion: The nature of chronic pelvic inflammation is qi deficiency and blood stasis in accordance with the theory of traditional Chinese medicine (TCM). As a drug that is indicated for chronic pelvic inflammation, its mechanism may be related to the improved blood circulation, accelerated inflammatory absorption and regulated immune function.

  11. Effect of Qi Ming Granule on the choroidal circulation in diabetic patients

    Directory of Open Access Journals (Sweden)

    Ke-Jun Li

    2016-03-01

    Full Text Available AIM:To investigate the effect of a Chinese medicine(Qi Ming granuleon the retinal and choroidal circulation in diabetes patients. METHODS: According to the results of fundus fluorescein angiography(FFA, all the 45 diabetes patients were divided into no diabetic retinopathy(NDRgroup and nonproliferative diabetic retinopathy(NPDRgroup. All subjects were examined by FFA and indocyanine green angiography(ICGAat the same time. After taken Qi Ming granule for 3mo, all subjects were examined by the same method. FFA and ICGA were used to evaluate the retinal and choroidal circulation and their features. The key points were filling time for the retinal and choroidal circulation before and after treatments. The accuracy data was used to evaluate the effect.RESULTS: After taken Qi Ming granule for 3mo, there were significant decrease of the retina and the choroid filling time in NDR and NPDR groups. The occurrence rate of various abnormal angiographic features were significantly decreased. CONCLUSION: Qi Ming granule can accelerate the blood flow of retina and choroid, improve the blood circulation in diabetes patients, and delay the occurrence and development of diabetic retinopathy.

  12. Brain areas involved in acupuncture needling sensation of de qi: a single-photon emission computed tomography (SPECT) study.

    Science.gov (United States)

    Chen, Jia-Rong; Li, Gan-Long; Zhang, Gui-Feng; Huang, Yong; Wang, Shu-Xia; Lu, Na

    2012-12-01

    De qi is a sensory response elicited by acupuncture stimulation. According to traditional Chinese medicine (TCM), de qi is essential for clinical efficacy. However, the understanding of the neurobiological basis of de qi is still limited. To investigate the relationship between brain activation and de qi by taking a single-photon emission computed tomography (SPECT) scan while applying acupuncture at TE5. A total of 24 volunteers were randomly divided into 4 groups, and received verum or sham acupuncture at true acupuncture point TE5 or a nearby sham point according to grouping. All subjects then received a (99m)Tc-ethylcysteinate dimer (ECD) SPECT scan. All six subjects in the verum acupuncture at true acupuncture point group experienced de qi sensation; in contrast, all six subjects in the sham acupuncture at the sham point group responded with nothing other than non-sensation. Compared to the scan results from subjects who experienced non-sensation, SPECT scans from subjects with de qi sensation demonstrated significant activated points mainly located in brodmann areas 6, 8, 19, 21, 28, 33, 35, 37, 47, the parahippocampal gyrus, lentiform nucleus, claustrum and red nucleus; deactivated points were seen in brodmann areas 9 and 25. Verum acupuncture at true acupuncture points is more likely to elicit de qi sensation. De qi sensations mainly resulted in brain area activations, but not deactivations. These brain areas are related to the curative effect of Te5. The acupuncture needle sensations of de qi and sharp pain are associated with different patterns of activations and deactivations in the brain.

  13. The Role of Rumination and Stressful Life Events in the Relationship between the Qi Stagnation Constitution and Depression in Women: A Moderated Mediation Model

    Directory of Open Access Journals (Sweden)

    Mingfan Liu

    2017-01-01

    Full Text Available The qi stagnation constitution is associated with depression in traditional Chinese medicine. It is unclear how rumination and stressful life events affect the relationship between the qi stagnation constitution and depression. The Qi Stagnation Constitution Scale, Ruminative Response Scale, Center for Epidemiologic Studies Depression Scale, and Adolescent Self-Rating Life Events Checklist were used to assess this association in 1200 female college students. The results revealed that the qi stagnation constitution was positively associated with depression. Furthermore, rumination was a partial mediator of the relationship between the qi stagnation constitution and depression. In addition, stressful life events moderated the direct effect and mediating effect of the qi stagnation constitution on depression. These findings indicate that rumination and stressful life events may affect the relationship between the qi stagnation constitution and depression in women.

  14. Quantification of DeQi sensation by visual analog scales in healthy humans after immunostimulating acupuncture treatment.

    Science.gov (United States)

    Kou, Wei; Gareus, Isabel; Bell, John D; Goebel, Marion U; Spahn, Günther; Pacheco-López, Gustavo; Bäcker, Marcus; Schedlowski, Manfred; Dobos, Gustav J

    2007-01-01

    Acupuncture is the most popular component of traditional Chinese medicine in Western countries. However, the mechanisms of its effects remain unclear. The therapeutic effect of acupuncture appears when a sensation of DeQi is achieved. We previously reported that repeated, but not single acupuncture treatment affected leukocyte circulation and blood pressure in healthy young humans. The objective of this study was to quantify DeQi sensation by using visual analog scales (VASs) and, to test whether DeQi induction is an important factor for the therapeutic effects of acupuncture in the same cohort. After either acupuncture or sham-acupuncture (placebo) treatment, a questionnaire containing five individual VASs was given to subjects to evaluate their DeQi sensation, including numbness, pressure, heaviness, warmth, and radiating paraesthesia, respectively. A separate VAS to measure their levels of anxiety during the treatment was also included. Our results showed that acupuncture significantly induced higher VAS values for numbness, pressure, warmth, and radiating paraesthesia, but not for heaviness than the placebo across three treatment sessions. Additionally, acupuncture did not induce higher anxiety levels than the placebo. These data confirm that VAS is an objective and reliable way to quantify DeQi sensation and, indicate that DeQi is unique to verum acupuncture treatment. Furthermore, either acupuncture-induced therapeutic effects or DeQi sensation should not be attributed to the stress-mediated effects. In summary, the induction of DeQi in each treatment session is an important factor for the physiological outcomes of repeated acupuncture treatment, and VASs offer objective, an easy and reliable way to assess it.

  15. More than DeQi: Spatial Patterns of Acupuncture-Induced Bodily Sensations

    OpenAIRE

    Won-Mo Jung; Woosun Shim; Taehyung Lee; Hi-Joon Park; Yeon-Hee Ryu; Florian Beissner; Younbyoung Chae

    2016-01-01

    Acupuncture uses needles to stimulate certain parts of the body, inducing a specific sensation, termed DeQi, which many regard as essential for acupuncture's therapeutic effect. Here, we used the newly developed tool, bodily sensation mapping, to investigate the spatial configuration of acupuncture-induced sensations throughout the body. Twenty-five participants randomly received acupuncture stimulation or tactile stimulation using a von Frey filament at four different acuoints (HT7, PC6, ST3...

  16. Thermographic Diagnosis for Curative Effect of Acupuncture and Qi-gong

    Institute of Scientific and Technical Information of China (English)

    JI Hong-wei; LI Ying; CHEN Jin-long; QIN Yu-wen

    2005-01-01

    Thermographic technique can be used to measure temperature distribution of body surface in real-time, non-contact and full-field, which has been successfully used in medical diagnosis, remote sensing, and NDT, etc. The authors have developed a thermographic experiment that can be applied to inspect the effect of action of acupuncture and qi-gong (a system of deep breathing exercises) by measuring the temperature of hand and arm. The observation is performed respectively by thermography for the dynamic changes of temperature of the arm and hand after acupuncture treatment and qi-gong treatment. Thermographic results show that the temperature on the collateral channels increases significantly. In the meantime, it can be seen that the above therapies of traditional Chinese medicine can stimulate the channel collateral system. This also contributes a new basis to the effect of action of the therapies of traditional Chinese medicine. The work shows that thermographic technique is a powerful tool for research in traditional Chinese medicine. In this paper, some thermal images are obtained from the persons treated with acupuncture and qi-gong.

  17. Effects of Qi therapy (external Qigong) on symptoms of advanced cancer: a single case study.

    Science.gov (United States)

    Lee, M S; Yang, S H; Lee, K K; Moon, S-R

    2005-12-01

    The aim of this study was to examine the effectiveness of Qi therapy (external Qigong) in the management of symptoms of advanced cancer in a man. We used a single case study design to evaluate the effectiveness of Qi therapy (external Qigong) in a 35-year-old man with advanced cancer (Stage IV) involving metastases in the stomach, lung and bone (Karnofsky performance scale: KPS, 40: requires special care and assistance, disabled). Treatment involved six days of pre-assessment, eight treatment sessions on alternate days over 16 days, and a two-week follow-up phase. A visual analogue scale (VAS) was used to assess the patient's self-reported symptoms of cancer over the intervention and follow-up periods. Following treatment, VAS scores' analysis revealed beneficial effects on pain, vomiting, dyspnoea, fatigue, anorexia, insomnia, daily activity and psychological calmness. These improvements were maintained over the two-week follow-up phase. After the first Qi therapy session, the patient discontinued medication and could sit by himself; after the fourth session, the patient was able to walk and use the toilet without assistance (improvement in KPS: 70: care for self, unable to perform normal activity or to do active work). Although limited by the single case study approach, our results support previous studies on this topic and provide reasons to conduct controlled clinical trials.

  18. Effects of warming yang and invigorating qi prescription on renin-angiotensin-aldosterone system in rats with heart failure after myocardial infarction

    Directory of Open Access Journals (Sweden)

    Lihua HAN

    Full Text Available Abstract This study investigated the effects of warming yang and invigorating qi prescription on renin-angiotensin-aldosterone system (RAAS in rats with heart failure after myocardial infarction. 126 rats were randomly divided into model group, sham operation, warming yang, invigorating qi, warming yang+invigorating qi, digoxin and captopril group for respective treatment. After intervention for 6, 8 and 10 weeks, the left ventricular ejection fraction (LVEF was calculated, and the plasma renin, angiotensin II and aldosterone levels were measured. Results showed that, after 6, 8 and 10 weeks, LVEF in warming yang, invigorating qi, warming yang+invigorating qi and captopril group was significantly higher than model group (P < 0.05, and the plasma renin, angiotensin II and aldosterone levels in warming yang, invigorating qi, warming yang+invigorating qi and captopril groups were significantly lower than model group (P < 0.05. Renin angiotensin II and aldosterone levels in invigorating qi, warming yang+invigorating qi and captopril groups after 10 weeks was significantly lower than after 6 weeks (P < 0.05; aldosterone level in captopril groups after 10 weeks was significantly lower than after 6 weeks (P < 0.05. Warming yang and invigorating qi prescription can improve LVEF in rats with heart failure after myocardial infarction, which may be related with the inhibition of RAAS activation.

  19. Discussions of the relationship of lung Qi,lung Yin and lung Yang%肺气肺阴肺阳关系探讨

    Institute of Scientific and Technical Information of China (English)

    邵雨萌; 张伟

    2012-01-01

    Based on the theory of Qi,we discussed the concept and connotation of lung Yin Qi and lung Yang Qi,and clarified the relationship of them. Lung Qi can be divided into lung Yin Qi and lung Yang Qi. Lung Yang is lung Yang Qi.and lung Yang deficiency refers toinsufficiency of lung Yang Qi. Lung Yin contains lung Yin Qi and lung fluid. Lung Yin deficiency contains insufficiency of lung Yin Qi and lung fluid.%从气的理论基础入手,探讨了肺阴气与肺阳气的概念、内涵,明确了肺气、肺阴、肺阳三者间的关系.认为肺气分为肺阴气与肺阳气.肺阳即肺阳气,肺阳虚即肺阳气不足;而肺阴包含肺阴气与肺津液,肺阴虚即肺阴气不足和肺津液亏虚.

  20. Influence of de qi on the immediate analgesic effect of SP6 acupuncture in patients with primary dysmenorrhoea and cold and dampness stagnation: a multicentre randomised controlled trial.

    Science.gov (United States)

    Zhao, Min-Yi; Zhang, Peng; Li, Jing; Wang, Lin-Peng; Zhou, Wei; Wang, Yan-Xia; She, Yan-Fen; Ma, Liang-Xiao; Wang, Pei; Hu, Ni-Juan; Lin, Chi; Hu, Shang-Qin; Wu, Gui-Wen; Wang, Ya-Feng; Sun, Jun-Jun; Jiang, Si-Zhu; Zhu, Jiang

    2017-07-11

    The aim of this multicentre randomised controlled trial was to investigate the contribution of de qi to the immediate analgesic effect of acupuncture in patients with primary dysmenorrhoea and the specific traditional Chinese medicine diagnosis cold and dampness stagnation. Eighty-eight patients with primary dysmenorrhoea and cold and dampness stagnation were randomly assigned to de qi (n=43) or no de qi (n=45) groups and underwent 30 min of SP6 acupuncture. The de qi group received deep needling at SP6 with manipulation using thick needles; the no de qi group received shallow needling with no manipulation using thin needles. In both groups the pain scores and actual de qi sensation were evaluated using a visual analogue scale for pain (VAS-P) and the acupuncture de qi clinical assessment scale (ADCAS), respectively. Both groups showed reductions in VAS-P, with no signficant differences between groups. ADCAS scores showed 43/43 and 25/45 patients in de qi and no de qi groups, respectively, actually experienced de qi sensation. Independent of original group allocation, VAS-P reductions associated with actual de qi (n=68) were greater than those without (28.4±18.19 mm vs 14.6±12.28 mm, p=0.008). This study showed no significant difference in VAS-P scores in patients with primary dysmenorrhoea and cold and dampness stagnation immediately after SP6 acupuncture designed to induce or avoid de qi sensation. Both treatments significantly reduced VAS-P relative to baseline. Irrespective of group allocation, patients experiencing actual de qi sensation demonstrated larger reductions in pain score relative to those without, suggesting greater analgesic effects. Chinese Clinical Trial Registry (ChiCTR-TRC-13003086); Results. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

  1. Pertinent Clinical Analysis of Diabetes and Insufficiency of the Spleen-qi%糖尿病与脾气虚的临床相关分析

    Institute of Scientific and Technical Information of China (English)

    何志明; 丘仁

    2002-01-01

    Objective To discuss and analyse the relationship between diabetes and insufficiency of the spleen- qi.which concerns pressure of cortraction and diastolization with no relationship with age. Course of disease, weight, type ofdiabetes, blood sugur lipid. Conclusion Diabetes is often comphcated with the insufficiency of the spleen - qi. To prevent andtreat diabetes. We should take spleen- strengthening- and- qi - replenishing into account on the basis of overal analysis ofsvmptoms and signs,the cause,nature and location of illness.

  2. Cardioprotection against ischemia/reperfusion injury by QiShenYiQi Pill® via ameliorate of multiple mitochondrial dysfunctions

    Directory of Open Access Journals (Sweden)

    Chen JR

    2015-06-01

    Full Text Available Jing Rui Chen,1–3 Jing Wei,1–3 Ling Yan Wang,1–3 Yan Zhu,1–3 Lan Li,1–3 Mary Akinyi Olunga,1–3 Xiu Mei Gao,1–3 Guan Wei Fan1–31Tianjin State Key Laboratory of Modern Chinese Medicine, Tianjin, People’s Republic of China; 2Key Laboratory of Pharmacology of Traditional Chinese Medicine Formulae, Ministry of Education, 3Institute of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, People’s Republic of ChinaAim: To investigate the potential cardioprotective effects of QiShenYiQi Pill® (QSYQ on myocardial ischemia/reperfusion (I/R injury through antioxidative stress and mitochondrial protection.Methods and results: Sprague Dawley rats were pretreated with QSYQ or saline for 7 days and subjected to ischemia (30 minutes occlusion of the left anterior descending coronary artery and reperfusion (120 minutes. Cardiac functions were evaluated by echocardiogram and hemodynamics. Myocardial mitochondria were obtained to evaluate changes in mitochondrial structure and function, immediately after 120 minutes reperfusion. Pretreatment with QSYQ protected against I/R-induced myocardial structural injury and improved cardiac hemodynamics, as demonstrated by normalized serum creatine kinase and suppressed oxidative stress. Moreover, the impaired myocardial mitochondrial structure and function decreased level of ATP (accompanied by reduction of ATP5D and increase in the expression of cytochrome C. Myocardial fiber rupture, interstitial edema, and infiltrated leukocytes were all significantly ameliorated by pretreatment with QSYQ.Conclusion: Pretreatment of QSYQ in Sprague Dawley rats improves ventricular function and energy metabolism and reduces oxidative stress via ameliorating multiple mitochondrial dysfunctions during I/R injury.Keywords: QSYQ, ischemia/reperfusion injury, energy metabolism, mitochondria

  3. Exploration of Stomach Qi in Treatise on Febrile Diseases%《伤寒论》“胃气”探析

    Institute of Scientific and Technical Information of China (English)

    何新慧

    2011-01-01

    探讨《伤寒论》中胃气的涵义,分析胃气和的生理状态、胃气不和的病理状态,并提出保护胃气的方法和措施.%This paper explores the meaning of stomach qi in Treatise on Febrile Diseases, analyzes the physiological state of stomach qi harmony, and the pathological state, classification, and therapeutical principal and method of stomach qi disorder, and proposes the measures to protect stomach qi.

  4. The effectiveness of a multidisciplinary QI activity for accidental fall prevention: Staff compliance is critical

    Directory of Open Access Journals (Sweden)

    Ohde Sachiko

    2012-07-01

    Full Text Available Abstract Background Accidental falls among inpatients are a substantial cause of hospital injury. A number of successful experimental studies on fall prevention have shown the importance and efficacy of multifactorial intervention, though success rates vary. However, the importance of staff compliance with these effective, but often time-consuming, multifactorial interventions has not been fully investigated in a routine clinical setting. The purpose of this observational study was to describe the effectiveness of a multidisciplinary quality improvement (QI activity for accidental fall prevention, with particular focus on staff compliance in a non-experimental clinical setting. Methods This observational study was conducted from July 2004 through December 2010 at St. Luke’s International Hospital in Tokyo, Japan. The QI activity for in-patient falls prevention consisted of: 1 the fall risk assessment tool, 2 an intervention protocol to prevent in-patient falls, 3 specific environmental safety interventions, 4 staff education, and 5 multidisciplinary healthcare staff compliance monitoring and feedback mechanisms. Results The overall fall rate was 2.13 falls per 1000 patient days (350/164331 in 2004 versus 1.53 falls per 1000 patient days (263/172325 in 2010, representing a significant decrease (p = 0.039. In the first 6 months, compliance with use of the falling risk assessment tool at admission was 91.5% in 2007 (3998/4368, increasing to 97.6% in 2010 (10564/10828. The staff compliance rate of implementing an appropriate intervention plan was 85.9% in 2007, increasing to 95.3% in 2010. Conclusion In our study we observed a substantial decrease in patient fall rates and an increase of staff compliance with a newly implemented falls prevention program. A systematized QI approach that closely involves, encourages, and educates healthcare staff at multiple levels is effective.

  5. About the neurobiological foundations of the De-Qi--stimulus-response relation.

    Science.gov (United States)

    Abad-Alegría, Francisco; Pomarón, Carlos

    2004-01-01

    In acupunctural reflexotherapy, it is usually stated that no appreciable therapeutic effect is obtained under a certain stimulation level, which is determined by the appearance of a particular sensation known as De-Qi. Given that afference control actions of the central nervous system do not work in this way, but rather adapt, with some peculiarities, to a classical schedule of proportionality between stimulus and response, our aim is to evaluate the extent to which acupunctural stimuli of increasing intensity can also increasingly modify neurophysiological parameters, by focusing on quantification of metameric levels, by an F-wave study and by means of somatosensorial evoked potential in the telencephalus. Twenty-one healthy volunteers were studied; values corresponding to the parameters indicated in a basal situation were taken and both a non-acupunctural point and the classical 4IG point were punctured simply, until the De-Qi sensation was obtained, following which, electrical stimulation was applied. Clear progressiveness was observed in the modifications of both the F-value and somesthesic potential values with increasing stimuli. It is true that the main inflexion occurs where obtaining De-Qi, but when overstimulation is applied from that time, greater variations take place, which is particularly patent in the case of somesthesic potential latency. Furthermore, the puncture of an extrachannel point shows that the mere puncturing of the skin does not produce any of the aforementioned effects. Despite the classical postulates, it is observed that, the greater the intensity of the acupunctural stimulus, the greater the modifications in the neurophysiological parameters studied. Control of somesthesic afference by acupuncture has already been demonstrated and quantified; now, however, the direct relation between the intensity of this effect and that of the stimulus used to produce it, which is quite far removed from the classical energetic conceptions, is also

  6. [Investigation of JinKui ShenQi pills by ultraviolet spectra and tandem mass spectrometry].

    Science.gov (United States)

    Li, Wen-lan; Sun, Zhi; Cheng, Bin; Ji, Yu-bin; Bai, Jing

    2008-08-01

    On the base of establishing the fingerprint of JinKui ShenQi pills, the ultraviolet spectra-mass spectrometry/mass spectrometry, method was used to identify the fingerprint. Seperation was performed on the Symmetry Shield RP18 (5 microm, 4. 6 mm X 15 mm) analytical column with mobile phase consisting of 1% acetic acid and acetonitrile with gradient elute at the flow rate of 1.0 mL x min(-1), and the ultraviolet detection wavelength was set at 248 nm. Using the above-mentioned chromatographic condition, the fingerprint of different samples was established and the same fingerprint was defined. The fingerprints of different samples were compared with similarity evaluation software published by Pharmacopeia committee codex (2004A). The mass spectrograph with API-ESI ionization source was used, setting the flow rate at 0.5 mL x min(-1) after splitting stream. The pressure of atomization room was 50 Psi, the flow rate of dry gas was 9.0 L x min(-1), the capillary voltage was 4 kV, and the transmission voltage was 70 V. The negative scanner mode was chosen, scan scope was 100-2000, using ion trap to analyze quasimolecular ion peak and the selected fragment ion, and TIC chromatography and second order mass chromatogram were recorded. The major constituents among in JinKui ShenQi pills from different origins were separated well by HPLC. Although there was difference among different origins, they showed nineteen identical characteristic absorption bands. Three fingerprints chemical compositions such as loganin, cinnamal and paeonol were identified based on the retention time and ultraviolet spectra of standard preparation. According to their ultraviolet spectra, molecular weight and fragmentation information, ten peaks in the fingerprint were identified by ultraviolet spectroscopy-mass, spectrometry/massg spectrometry. They are 1,2,3-tri-O-galloyl-glucose, loganin, paeoniflorin, 1,2,3,6-tetro-O-galloyl-glucose, soya-cerebroside, cornuside, and PGG, benzoyl

  7. A Clinical Study on the Effects of Dong-Qi Acupuncture Treatment for Patents with low back pain and sciatica

    Directory of Open Access Journals (Sweden)

    Lee Kwang-Ho

    2005-12-01

    Full Text Available Objective : The purpose of this study is to observe the effects of Dong-Qi acupuncture treatment for the patients with low back pain and sciatica. Methods : 60 patients were divided into two, Group A of 30 persons and Group B of 30 persons. Only Group A was treated with Dong-Qi acupuncture treatment, Group B was treated with just Dong-Si acupuncture treatment. Results : In VAS, Group A is 6.57±1.91 and Group B is 5.20±2.22(P=0.013. In Improvement index, Group A is 0.2295±0.1036 and Group B is 0.1545±0.0895 (P=0.004. Conclusion : We knew that Dong-Qi acupuncture treatment is more effective.

  8. An intermediate-luminosity-optical-transient (ILOT) model for the young stellar object ASASSN-15qi

    CERN Document Server

    Kashi, Amit

    2016-01-01

    We construct a scenario where the outburst of the young-stellar-object ASASSN-15qi is an intermediate luminosity optical transient (ILOT). In this scenario a sub-Jupiter young planet was tidally destructed on to a young main-sequence star. The system is young, therefore the radius of the planet is larger than its final value, and consequently it has smaller density. The lower density allows the tidal destruction of the young Saturn-like planet on to the main-sequence star of mass $\\approx 2.4 ~M_\\odot$, resulting in a formation of a disc and a gravitationally-powered ILOT. Unlike the case of the more energetic ILOT V838~Mon, the mass of the destroyed planet is too low to inflate a giant envelope, and hence the merger remnant stays hot. If our suggested model holds, this ILOT possesses two interesting properties: (1) its luminosity and total energy are below those of novae, and (2) it is not as red as other ILOTs. The unusual outburst of ASASSN-15qi, if indeed is an ILOT, further increases the diversity of the...

  9. [Study on quality evaluation of Panax ginseng based on effects for replenishing qi and preventing exhaustion].

    Science.gov (United States)

    Wang, Liyan; Tian, Yixin; Li, Haitao; Wang, Li; Lv, Xiaojun

    2012-07-01

    Based on the effect for replenishing Qi and preventing exhaustion, this essay provides a method to rebuild the quality evaluation system of Panax ginseng. As an independent medical system, the traditional Chinese medicine (TCM) science lacks enough credible evidences to support its theory and thereby wants more relevant studies. Current, it is a misunderstanding for experimental studies on TCM to prove TCM drugs from the angle of western medicine. Therefore, following study modes are recommended to researchers focusing on either the theory of the unique importance of class origin or the theory of the unique importance of techniques. Under the guidance of TCM theories, a new TCM assessment mode, consisting of clinical efficacy, pharmacological effect and effective components, is established in line with clinical application of TCMs. Studies on Chemical fingerprint or active ingredient are made on effective components. In-depth studies are worth to the viewpoint to rebuild the TCM quality reassessment system. On the basis of analysis on ancient herbal literatures and experience in clinical application of TCMs, the author proves the irreplaceable effect of P. ginseng. (pure ginseng decoction) is to replenish Qi and prevent exhaustion. Based on the major effect, a pharmacological model is established in combination with modern clinical efficacy to screen effective components of ginseng herbs and make a quality assessment on safety and efficiency of clinical application of P. ginseng, in order to provide theoretical and experimental basis for cultivation, development and utilization of P. ginseng resources on Changbai mountain.

  10. Comparative kinetics of Qi site inhibitors of cytochrome bc1 complex: picomolar antimycin and micromolar cyazofamid.

    Science.gov (United States)

    Li, Hui; Zhu, Xiao-Lei; Yang, Wen-Chao; Yang, Guang-Fu

    2014-01-01

    Antimycin and cyazofamid are specific inhibitors of the mitochondrial respiratory chain and bind to the Qi site of the cytochrome bc1 complex. With the aim to understand the detailed molecular inhibition mechanism of Qi inhibitors, we performed a comparative investigation of the inhibitory kinetics of them against the porcine bc1 complex. The results showed that antimycin is a slow tight-binding inhibitor of succinate-cytochrome c reductase (SCR) with Ki  = 0.033 ± 0.00027 nm and non-competitive inhibition with respect to cytochrome c. Cyazofamid is a classical inhibitor of SCR with Ki  = 12.90 ± 0.91 μm and a non-competitive inhibitor with respect to cytochrome c. Both of them show competitive inhibition with respect to substrate DBH2 . Further molecular docking and quantum mechanics calculations were performed. The results showed that antimycin underwent significant conformational change upon the binding. The energy barrier between the conformations in the crystal and in the binding pocket is ~13.63 kcal/mol. Antimycin formed an H-bond with Asp228 and two water-bridged H-bonds with Lys227 and His201, whereas cyazofamid formed only one H-bond with Asp228. The conformational change and the different hydrogen bonding network might account for why antimycin is a slow tight-binding inhibitor, whereas cyazofamid is a classic inhibitor.

  11. PREFACE: International Conference on Quantum Optics and Quantum Information (icQoQi) 2013

    Science.gov (United States)

    2014-11-01

    Quantum Information can be understood as being naturally derived from a new understanding of information theory when quantum systems become information carriers and quantum effects become non negligible. Experiments and the realization of various interesting phenomena in quantum information within the established field of quantum optics have been reported, which has provided a very convenient framework for the former. Together, quantum optics and quantum information are among the most exciting areas of interdisciplinary research in modern day science which cover a broad spectrum of topics, from the foundations of quantum mechanics and quantum information science to the introduction of new types of quantum technologies and metrology. The International Conference on Quantum Optics and Quantum Information (icQoQi) 2013 was organized by the Faculty of Science, International Islamic University Malaysia with the objective of bringing together leading academic scientists, researchers and scholars in the domain of interest from around the world to share their experiences and research results about all aspects of quantum optics and quantum information. While the event was organized on a somewhat modest scale, it was in fact a rather fruitful meeting for established researchers and students as well, especially for the local scene where the field is relatively new. We would therefore, like to thank the organizing committee, our advisors and all parties for having made this event successful and last but not least would extend our sincerest gratitude to IOP for publishing these selected papers from icQoQi2013 in Journal of Physics: Conference Series.

  12. Treating urinary tract infections from the Qi theory%从气论治尿路感染

    Institute of Scientific and Technical Information of China (English)

    夏良洪

    2016-01-01

    Urinary tract infection is a common disease; This disease should be treated from Qi theory of governance to regulate Qi for the bladder function.%尿路感染是常见病、多发病,笔者认为从调畅气机论治本病,分别为清肺降气启上焦气机、疏肝调理中焦气机,达到调畅膀胱气化功能的目的。

  13. Correlation Study of PtfV1 with Heart-Qi Deficiency Syndrome in Patients with Hypertensive Left Ventricular Hypertrophy

    Institute of Scientific and Technical Information of China (English)

    杨传华; 陆峰

    2002-01-01

    @@ It is generally believed that the change of p-wave terminal force in lead V1 (PtfV1) is associated with the inner diameter of left atrium, left ventricular compliance,and ventricular diastolic function. The increase of negative value of PtfV1 in essential hypertensive (EH) patients with left ventricular hypertrophy (LVH) indicates the cardiac function may be damaged. In order to explore the relationship between Heart-Qi Deficiency Syndrome (HQDS) of TCM and PtfV1 level in hypertensive LVH patients, correlation analysis of scores of Heart-Qi Deficiency Syndrome and negative value of PtfV1 was made by the authors.

  14. A Clinical Study on Treatment of Senile Psoriasis by Replenishing Qi to Activate Blood--A Report of 40 Cases

    Institute of Scientific and Technical Information of China (English)

    刘洪普; 谭奇纹; 刘华昌

    2004-01-01

    40 cases of senile psoriasis were treated by the therapeutic principle of replenishing qi to activate blood,and the changes of T lymphocyte subgroups and indexes of haemorheology were observed. The results showed that CD4 was significantly increased, CDs significantly decreased, and the CD4/CD8 ratio significantly raised; and that the specific viscosity of whole blood at high shearing rate, and at low shearing rate, the specific viscosity of plasma, packed cell volume, and fibrinogen all significantly decreased after treatment. It is therefore concluded that the therapeutic method of replenishing qi to activate blood can exert an effect of improving immunologic function and blood circulation.

  15. Clinical Research into Ke Min Yin for Treatment of Persistent Allergic Rhinitis in Patients with Qi Deficiency and Blood Stasis

    Institute of Scientific and Technical Information of China (English)

    刘巧平; 刘建华; 刘大新

    2003-01-01

    @@ Persistent allergic rhinitis (PAR) is one of the common diseases at ear-nose-throat department. From August 1998 to May 2001, we randomly selected 60 cases of PAR with qi deficiency and blood stasis for a clinical observation. 30 patients in the treatment group were treated with Ke Min Yin (克敏饮), a herbal medicine, to supplement qi, expel wind, nourish blood and promote blood circulation; and the other 30 cases in the control group were treated with cetrine. Through systematic observation and statistical processing, the clinical research is summarized and reported in the following.

  16. Discussion on the Theory of All Diseases Resulting from Qi Disorder in Terms of Spleen%从脾论“百病生于气”

    Institute of Scientific and Technical Information of China (English)

    霍秀红

    2015-01-01

    气学说是重要的中医理论之一,历代医家均相当重视气在人体的作用,更有《黄帝内经》提出“百病生于气”。为了有利于指导临床,笔者试以“百病生于气”立论,从中气为诸气之本、脾气为脾脏之本以及脾气虚为脾病之本等角度,对“百病生于气”作以阐释。%Qi theory is one of the important theories of TCM. Ancient Traditional Chinese doctors attached great importance to the role of qi in the human body. What’ s more, theory of all diseases result from qi disorder was proposed in Huangdi Neijing. In order to guide the clinical practice, based on the argument of all diseases resulting from qi disorder, the author explained this theory from several aspects, such as middle qi being the basis of the whole body’ s qi, spleen qi being the basis of the spleen and qi deficiency in the spleen being the basis of the spleen diseases.

  17. Preliminary molecular basis of Danggui-buxue-tang on Qi deficiency and blood stasis syndrome

    Institute of Scientific and Technical Information of China (English)

    LIU Ya; LI Xiao-hui

    2008-01-01

    Objective To study the molecular biology mechanism of Danggui-buxue-tang on tonifying Qi and controlling blood circulation through modulation the immune functional genes. Methods Rats were randomly divided into control group, model group, and Danggui-buxue-tang group. Effect of Dang-guibuxue-tang on mRNA expressions of IL-1β, TNF-α, HSP-70, NF-kB, p38MAPK and JNK in blood cells of rats with Qi deficiency and blood stasis were measured with real-time fluorescent quantitative-PCR at 5th, 14th and 28th day. And that in artery wall were determined at the 28th day. NF-kB/p65 and p-c-jun protein expressions in rat artery wall were detected by western blotting as well. Results In model group, TNF-α, IL-1β, NF-kB, HSP-70, p38MAPK and JNK mRNA expression in blood cell increased significantly compared with control group. Compared with model group, mRNA expression of IL-1βand JNK decreased significantly; TNF-α decreased at 5th, 14th day;HSP-70, p38MAPK decreased at 14th, 28th day; NF-kB decreased at 28th day. In model group, TNF-α, IL-1β, NF-kB, p38MAPK and JNK mRNA expression in artery increased compared with control group, excluded HSP-70, and that in Danggui-buxue-tang group decreased significantly. In model group, NF-kB/p65 and p-c-jun protein expression in artery increased compared with control group, and that in Danggui-buxue-tang group decreased significantly. Conclusions The effects of Dang-guibuxuetang on Qi deficiency and blood stasis syndrome was brought from the regulating of cytokine network at multi-link and multi-target, NF-kB, p38MAPK and JNK signal transduction pathways included. Through which the immune system and whole body reached to a functional balance status.

  18. [Analysis in pulmonary ventilatory function from 100 patients with ano-rectal diseases caused by deficiency of qi].

    Science.gov (United States)

    Wang, W

    1999-03-01

    To explore the pathogenesis of ano-rectal diseases caused by deficiency of Qi, which is correlated with obstruction of pulmonary ventilation. The pulmonary ventilatory function was measured in 100 patients with the internal piles, the interno-external hemorrhoid and prolapse of rectum, the prolapse of anus was the principal symptom of them. Data from the 100 patients showed that 67% of them were diagnosed with the obstruction of pulmonary ventilation, the ratio was far less in the health control group. FEV 1.0 (mean +/- s) (2011.65 +/- 875) ml, MMF (1.84 +/- 1.24) L/s and PEF (2.34 +/- 1.51) L/s in male patients, (1551.54 +/- 514) ml, (1.57 +/- 0.62) L/s and (1.85 +/- 0.92) L/s in female patients, but those values were higher in the control than in the patients. The statistical analysis was performed and the difference was significant between patients and the control group (P < 0.01). The patients with ano-rectal diseases caused by deficiency of Qi accompanied with obstruction of pulmonary ventilation in different degree and varied sorts, it confirmed that the pathogenesis of ano-rectal diseases caused by deficiency of Qi is related with "sinking of pectoral Qi".

  19. [Analysis on establishment and affecting factors of qi stagnation and blood stasis rat model].

    Science.gov (United States)

    Wang, Tingting; Jia, Cheng; Chen, Yu; Li, Xin; Cheng, Jiayi

    2012-06-01

    To study on the method for establishing the Qi stagnation and blood stasis rat model and analyze the affecting factors. The orthogonal design was adopted to study the influences of joint stimulations including noise, light, electricity, ice water bath, tail-clamping on model rats. The 'flying spot' method was used to dynamically simulate blood flow velocity in microcirculation. the pressure sensing technology of MOTO was adopted to detect hemorheology-related indicators. And the coagulation method was used to detect blood coagulation-related indicators. Compared with the negative control group, all model groups showed significant reduction in the blood flow velocity in mesenteric microcirculation and increase in the whole blood viscosity at high, medium and low shear rate, the plasma viscosity and the fibrinogen content in four blood coagulation indicators. Noise, light, electricity, tail-clamping, bondage and icewater-bath make significant impact on model rats.

  20. 'Reversing' the Flow of the Ancient Chinese Calendrical Subseasonal Phases Jie Qi in Australia: The Construction of a Chinese Medical & Agricultural Lunisolar Calendar (Northern and Southern Hemispheres )( Continued )

    Institute of Scientific and Technical Information of China (English)

    Rey Tiquia

    2008-01-01

    Jie qi(subseasonal phases or solar qi)eonstitutes the solar component of the ancient Chinese lunisolar calendar.It divides the year into twenty-four suhseasonal phases i.e. li chun (beginning of spring) ,chun fen (spring equinox),etc.From the premodern perspective of Traditional Chinese Medicine(TCM ),normal climate change(q/hou b/an q/an)moves inharmony with the temporal flow of the qi(qi yun)and is thus beneficial to human health.However,abnonnal,abrupt weatheror climatic changes like those weather features of being too cold or too hot,too windy,too humid,too dry or a combination oftwo or more of these weather/climatic features which occur out of season can lead to 'seasonal diseases' (shi bing)or'diseases brought about by external influences' (wai gan zhi bing)or by the'six excessive climatic qi etiological factors' (liuBut the temporal flow of the subseasonal qi (qi yun) in Australia is the reverse of that of the northern hemisphericalregions of China,United States and Europe.This situation thus leads to a temporal desynchronisation of TCM practice andsouthern hemisphere.Having this calendrical tool, Chinese medicine practitioners in Australia can 'reverse'their clinical ac-tivities in accordance with the natural rhythm of the seasons here.

  1. Evidence-based medical quality management in dialysis--Part I: Routine implementation of QiN, a German quality management system.

    Science.gov (United States)

    Stoffel, M P; Barth, C; Lauterbach, K W; Baldamus, C A

    2004-09-01

    Increasing medical complexity, centrifugal forces of medical subspecialization and growing economic constraints are the key reasons for the introduction of quality management into routine care processes such as dialysis. Adequate quality assurance and improvement must be implemented in order to supply medical staff, care providers, and patients with the necessary information on critical issues of clinical management of dialysis patients. QiN (Quality in Nephrology), the quality management program of the largest German dialysis provider, is outlined here as a practicable example. The first of 2 parts provides information on the structure, implementation of QiN and achieved clinical improvement in routine care. The second part (quotation) analyzes longitudinal data in order to differentiate whether observed improvements during more than 5 years of QiN can be ascribed to the intervention (application of QiN) or whether they are due to other factors such as generally improved medical knowledge.

  2. On Chinese-English Translation of Tourist Attraction in Cross-cultural Perspective--Taking Qi Culture as An Example

    Institute of Scientific and Technical Information of China (English)

    张滕龙

    2014-01-01

    Tourist textsfeature vividness and distinctiveness and its translation is a typical cross-cultural activity.By applying cross-cultural consciousness to the tourist material's translation, foreigners can understand the cultural connotation easily. Therefore, cross-cultural consciousness plays an important role in the translation of tourist materials.This thesis, taking Qi culture as an exam-ple, explores some typical tourist attractions from perspectives of historical allusions and legend as well as traditional customs. The analysis of Qi cultural connotation concludes business culture, Pu culture and filial piety culture. So, in order to transmit the cul-tural information to foreign tourists accurately, it is necessary to apply inter-cultural consciousness to the translation of tourist texts.

  3. Investigation into the Qi silk dress cultural characteristics%齐国服饰文化特征探悉

    Institute of Scientific and Technical Information of China (English)

    宋金英; 王婧

    2011-01-01

    Based on persuasive evidences, combined with the theory on history, ancient books and records, the hundred schools of thoughts and their exponents during the period from pre-Qin times to the early years of the Han Dynasty, this article attempts to analyze the basic characteristics of the culture about Qi silk dress features,and seeks to find the shape, character, aesthetic orientation, as well as the deep-seated historical cultural values in "Qi silk dress".%以推理实证为基础,结合史论、典籍及诸子百家的哲学观点,试图分析齐国丝绸服饰文化的基本特征,力求寻找"齐国服饰"的形制、特点、审美取向,以及所包含的深层次的历史性文化价值.

  4. The regulation of method of tonifying Qi and activating blood circulation in the related gene expressions after spinal cord injury

    Institute of Scientific and Technical Information of China (English)

    Xiao Fan; Li Zhang

    2016-01-01

    Spinal cord injury is a disease of high incidence and low cure rate without any ideal treatment. Among the complex pathological reactions, the post-injury abnormal expressions of many genes may be an important one. Method of tonifying Qi and activating blood circulation, which is one of the most important treatments of spinal cord injury in Traditional Chinese Medicine and has been used extensively in clinic, is proved to be effective in the treatment of spinal cord injury. Recently, many scholars have carried out a lot of studies in this filed and acquired notable achievements. The essay concludes mechanisms of the regulation of method of tonifying Qi and activating blood circulation in the related gene expressions after spinal cord injury to provide new thoughts and new methods for the treatment and study of spinal cord injury.

  5. Clinical Significance and Changes of ECG in the Patients with Cardiac Deficiency of the Qi and the Yin

    Institute of Scientific and Technical Information of China (English)

    LIN Qi-Shanxi

    2005-01-01

    In order to explore the changes and clinical significance of ECG in the patients with cardiac deficiency of the Qi and Yin, 124 patients with heart diseases were examined by means of ECG. The results showed that the prevalence of left ventricular hypertrophy in cardiac deficiency of the Qi (CDQ) was obviously higher than that of cardiac deficiency of the Yin (CDY). The higher prevalence of tachycardia occurred in the patients with CDY.The prevalence of the Q - T interval prolongation and abnormalities of ST - T segment in the patients with CDY was also higher than that of CDQ. The difference between two groups suggests that the diagnosis of two syndromes by ECG may be of important value.

  6. Biological basis of “depression with liver-qi stagnation and spleen deficiency syndrome”: A digital gene expression profiling study

    Directory of Open Access Journals (Sweden)

    Junling Li

    2015-07-01

    Conclusions: Hnf4α, Hnf4γ and Cyp1a1 are involved in “depression with liver-qi stagnation and spleen deficiency syndrome”. These findings indicate that depressed rats with liver-qi stagnation and spleen deficiency syndrome are at risk of liver diseases. Furthermore, our results will inform exploration of the etiology of depression and help in the development of effective therapeutic strategies.

  7. Partly Separated Activations in the Spatial Distribution between de-qi and Sharp Pain during Acupuncture Stimulation: An fMRI-Based Study.

    Science.gov (United States)

    Sun, Jinbo; Zhu, Yuanqiang; Jin, Lingmin; Yang, Yang; von Deneen, Karen M; Qin, Wei; Gong, Qiyong; Tian, Jie

    2012-01-01

    Nowadays, functional magnetic resonance imaging (fMRI) has become one of the most important ways to explore the central mechanism of acupuncture. Among these studies, activations around the somatosensory-related brain network had the most robust blood oxygen level-dependent (BOLD) responses. However, due to the insufficient control of the subjective sensations during acupuncture stimulation, whether these robust activations reflected the pattern of de-qi, sharp pain, or mixed (de-qi + sharp pain) sensations was largely unknown. The current study recruited 50 subjects and grouped them into two groups according to whether he/she experienced sharp pain during acupuncture stimulation to give a definite answer to the aforesaid question. Our results indicated that BOLD responses associated with de-qi during acupuncture stimulation at ST36 were activation dominated. Furthermore, both the quantitative and qualitative differences of BOLD responses between de-qi and mixed sensations evoked by acupuncture stimulation were significant. The pattern of BOLD responses of sharp pain might be partly separated from that of de-qi in the spatial distribution. Therefore, we proposed that in order to explore the specific central mechanism of acupuncture, subjects with sharp pain should be excluded from those with only de-qi.

  8. Partly Separated Activations in the Spatial Distribution between de-qi and Sharp Pain during Acupuncture Stimulation: An fMRI-Based Study

    Directory of Open Access Journals (Sweden)

    Jinbo Sun

    2012-01-01

    Full Text Available Nowadays, functional magnetic resonance imaging (fMRI has become one of the most important ways to explore the central mechanism of acupuncture. Among these studies, activations around the somatosensory-related brain network had the most robust blood oxygen level-dependent (BOLD responses. However, due to the insufficient control of the subjective sensations during acupuncture stimulation, whether these robust activations reflected the pattern of de-qi, sharp pain, or mixed (de-qi + sharp pain sensations was largely unknown. The current study recruited 50 subjects and grouped them into two groups according to whether he/she experienced sharp pain during acupuncture stimulation to give a definite answer to the aforesaid question. Our results indicated that BOLD responses associated with de-qi during acupuncture stimulation at ST36 were activation dominated. Furthermore, both the quantitative and qualitative differences of BOLD responses between de-qi and mixed sensations evoked by acupuncture stimulation were significant. The pattern of BOLD responses of sharp pain might be partly separated from that of de-qi in the spatial distribution. Therefore, we proposed that in order to explore the specific central mechanism of acupuncture, subjects with sharp pain should be excluded from those with only de-qi.

  9. The impact of brief quality improvement (QI projects by medical students in primary care in Gauteng or the North West Province, South Africa

    Directory of Open Access Journals (Sweden)

    Claire van Deventer

    2012-08-01

    Full Text Available Background: The Integrated Primary Care (IPC rotation is undertaken over six weeks by final year medical students at the University of Witwatersrand. Students are placed in either rural or urban primary health care centres based in Gauteng or the North West Province. Aspart of the IPC rotation, students undertake short quality improvement (QI projects. The purpose of this study is to evaluate the impact of the QI projects undertaken over the period stretching from 2006 to 2010.Methods: An observational study of QI reports done by students. Project reports assessed and compared to site marks, indicators of learning assessed and individual and group marks compared.Results: Of 274 projects undertaken, 223 (81.4% were available for evaluation. Geographical placements and QI themes were categorised. Management issues were most frequently identified as being problematic followed by chronic illnesses. Understanding and applying the principles of QI was partially achieved and gaps were identified for future projects. The most common intervention was training of personnel and design and distribution of posters or pamphlets.Conclusions: Most QI projects were well thought out and relevant to the chosen setting. In the majority of cases, a great deal of effort and creativity went into the process and skills other than clinical skills were employed such as writing, presentation of data in graphs and tables. Integration of theory and practice was achieved only partially.

  10. The impact of brief quality improvement (QI projects by medical students in primary care in Gauteng or the North West Province, South Africa

    Directory of Open Access Journals (Sweden)

    Claire van Deventer

    2012-02-01

    Full Text Available Background: The Integrated Primary Care (IPC rotation is undertaken over six weeks by final year medical students at the University of Witwatersrand. Students are placed in either rural or urban primary health care centres based in Gauteng or the North West Province. As part of the IPC rotation, students undertake short quality improvement (QI projects. The purpose of this study is to evaluate the impact of the QI projects undertaken over the period stretching from 2006 to 2010. Methods: An observational study of QI reports done by students. Project reports assessed and compared to site marks, indicators of learning assessed and individual and group marks compared.Results: Of 274 projects undertaken, 223 (81.4% were available for evaluation. Geographical placements and QI themes were categorised. Management issues were most frequently identified as being problematic followed by chronic illnesses. Understanding and applying the principles of QI was partially achieved and gaps were identified for future projects. The most common intervention was training of personnel and design and distribution of posters or pamphlets.Conclusions: Most QI projects were well thought out and relevant to the chosen setting. In the majority of cases, a great deal of effort and creativity went into the process and skills other than clinical skills were employed such as writing, presentation of data in graphs and tables. Integration of theory and practice was achieved only partially.

  11. Atomistic determinants of co-enzyme Q reduction at the Qi-site of the cytochrome bc1 complex

    Science.gov (United States)

    Postila, Pekka A.; Kaszuba, Karol; Kuleta, Patryk; Vattulainen, Ilpo; Sarewicz, Marcin; Osyczka, Artur; Róg, Tomasz

    2016-09-01

    The cytochrome (cyt) bc1 complex is an integral component of the respiratory electron transfer chain sustaining the energy needs of organisms ranging from humans to bacteria. Due to its ubiquitous role in the energy metabolism, both the oxidation and reduction of the enzyme’s substrate co-enzyme Q has been studied vigorously. Here, this vast amount of data is reassessed after probing the substrate reduction steps at the Qi-site of the cyt bc1 complex of Rhodobacter capsulatus using atomistic molecular dynamics simulations. The simulations suggest that the Lys251 side chain could rotate into the Qi-site to facilitate binding of half-protonated semiquinone – a reaction intermediate that is potentially formed during substrate reduction. At this bent pose, the Lys251 forms a salt bridge with the Asp252, thus making direct proton transfer possible. In the neutral state, the lysine side chain stays close to the conserved binding location of cardiolipin (CL). This back-and-forth motion between the CL and Asp252 indicates that Lys251 functions as a proton shuttle controlled by pH-dependent negative feedback. The CL/K/D switching, which represents a refinement to the previously described CL/K pathway, fine-tunes the proton transfer process. Lastly, the simulation data was used to formulate a mechanism for reducing the substrate at the Qi-site.

  12. [Health assessment of Qi'ao Island mangrove wetland ecosystem in Pearl River Estuary].

    Science.gov (United States)

    Wang, Shu-Gong; Zheng, Yao-Hui; Peng, Yi-Sheng; Chen, Gui-Zhu

    2010-02-01

    Based on the theories of wetland ecosystem health and by using "Pressure-State-Response" model, a health assessment indicator system for Qi' ao Island mangrove wetland ecosystem in Pearl River Estuary was built, and the assessment indices, assessment criteria, indices weighted values, assessment grades, and assessment methods were established to assess the health state of this ecosystem. In 2008, the overall health index of this ecosystem was 0.6580, health level was of grade II (healthy), and the pressure, state, and response indices were 0.3469, 0.8718, and 0.7754, respectively, suggesting that this ecosystem was good in state and response, but still had definite pressure. As a provincial nature reserve, this ecosystem was to be further improved in its health level. However, the research on the health assessment of mangrove wetland ecosystem was still young. Further studies should be made on the selection of assessment indices, long-term oriented monitoring of these indices, and quantification of the relations between ecosystem health level and ecosystem services.

  13. Overview of Pectoral Qi Theory and Modern Research Progress%宗气理论概述及现代研究进展*

    Institute of Scientific and Technical Information of China (English)

    杨燕; 胡镜清; 彭锦; 陈亦辉

    2014-01-01

    本文通过系统回顾宗气理论相关文献,对宗气的定义沿革、生理功能、虚实变化、宗气亏虚临床表现及宗气理论的现代研究进展等内容进行总结和归纳,以深化对宗气内涵的理解。宗气内涵主要有以下4种观点:宗气是由肺所吸入的自然界的清气结合脾胃化生的水谷之气积于胸中而成;宗气的实质即心肺阳气;宗气是升至胸中之谷气的一种特称;宗气是积于胸中并在左乳下跳动的动气。其生理功能包括走息道以司呼吸,贯心脉以行气血,宗心肺而主燮理,统诸气而安脏腑、布津液,抵御外邪,提携神明、保持神思脑力健旺,职司视、听、声、色、嗅、动,汇元气以全生机。宗气失常主要表现在“虚实”二端,其中虚表现为宗气亏虚、宗气下陷,实表现为宗气痹阻、宗气上逆。宗气亏虚证的常见临床表现主要症状为气短,动则加重,甚则气喘。伴见症状为面色白或晦暗、神疲、乏力、少气懒言、不寐、头晕、目眩、自汗、消瘦、舌淡暗、苔薄白、脉沉、脉细或脉弱。并发症状为心肺气血运行不畅之胸闷、胸痛、心悸、紫绀、咳嗽、咳痰、大便秘结;脾虚不运之纳呆、便溏、腹胀;阳虚气化失利之四肢逆冷、畏寒、浮肿、小便不利、口干。另外,从宗气论治的疾病,以心肺疾病为主,逐渐扩展到其他系统疾病。同时,以宗气理论指导治疗疾病的临床研究多有报道,从现代医学角度对宗气的实质也进行了探讨。总而言之,宗气理论提出很早,但系统研究尚难以满足临床诊疗需要,许多问题有待深入研究和解决。%In this paper, through a systematic review of literatures on pectoral qi theory, we summarized the defini-tion of pectoral qi, physiological function, deficiency-excess changes, clinical manifestations of pectoral qi deficiency and modern research

  14. Huang Qi Decoction Prevents BDL-Induced Liver Fibrosis Through Inhibition of Notch Signaling Activation.

    Science.gov (United States)

    Zhang, Xiao; Xu, Ying; Chen, Jia-Mei; Liu, Cheng; Du, Guang-Li; Zhang, Hua; Chen, Gao-Feng; Jiang, Shi-Li; Liu, Cheng-Hai; Mu, Yong-Ping; Liu, Ping

    2017-01-01

    Notch signaling has been demonstrated to be involved in ductular reactions and fibrosis. Previous studies have shown that Huang Qi Decoction (HQD) can prevent the progression of cholestatic liver fibrosis (CLF). However, whether HQD affects the Notch signaling pathway is unclear. In this study, CLF was established by common bile duct ligation (BDL) in rats. At the end of the first week, the rats were randomly divided into a model group (i.e., BDL), an HQD group, and a sorafenib positive control group (SORA) and were treated for 3 weeks. Bile duct proliferation and liver fibrosis were determined by tissue staining. Activation of the Notch signaling pathway was evaluated by analyzing expressions of Notch-1, -2, -3, and -4, Jagged (JAG) 1, and Delta like (DLL)-1, -3, and -4. The results showed that HQD significantly reduced the deposition of collagen and the Hyp content of liver tissue and inhibited the activation of HSCs compared with the BDL group. In addition, HQD significantly decreased the protein and mRNA expressions of TGF-[Formula: see text]1 and [Formula: see text]-SMA. In contrast, HQD significantly enhanced expression of the Smad 7 protein. HQD also reduced biliary epithelial cell proliferation, and reduced the mRNA levels of CK7, CK8, CK18, SRY-related high mobility group-box gene (SOX) 9, epithelial cell adhesion molecule (EpCAM) and the positive areas of CK19 and OV6. In addition, the mRNA and protein expressions of Notch-3, -4, JAG1, and DLL-1, -3 were significantly reduced in the HQD compared to the BDL group. These results demonstrated that HQD may prevent biliary liver fibrosis through inhibition of the Notch signaling pathway, and it may be a potential treatment for cholestatic liver disease.

  15. Effects of Chai-Qin-Cheng-Qi Decoction on cefotaxime in rats with acute necrotizing pancreatitis

    Institute of Scientific and Technical Information of China (English)

    Li-Hui Deng; Da-Kai Xiang; Ping Xue; Hai-Yan Zhang; Lei Huang; Qing Xia

    2009-01-01

    AIM: To investigate the effect of Chai-Qin-Cheng-Qi Decoction (CQCQD) on cefotaxime (CTX) concentration in pancreas of rats with acute necrotizing pancreatitis (ANP).METHODS: Sixty healthy male Sprague-Dawley rats were divided randomly into an ANP group (ANP model + CTX, n = 20), treatment group (ANP model + CTX + CQCQD, n = 20) and control group (normal rats + CTX, n = 20). ANP models were induced by retrograde intraductal injection of 3.5% sodium taurocholate (1 mL/kg), and the control group was injected intraductally with normal saline. All rats were injected introperitoneally with 0.42 g/kg CTX (at 12-h intervals for a continuous 72 h) at 6 h after intraductal injection. Meanwhile, the treatment group received CQCQD (20 mL/kg) intragastrically at 8-h intervals, and the ANP and control group were treated intragastrically with normal saline. At 15 min after the last CTX injection, blood and pancreas samples were collected for the determination of CTX concentration using validated high-performance liquid chromatography. Pathological changes and wet-to-dry-weight (W/D) ratio of pancreatic tissue were examined.RESULTS: Serum CTX concentrations in three groups were not significantly different. Pancreatic CTXconcentration and penetration ratio were lower in ANP group vs control group (4.4 ±0.6 mg/mL vs 18.6±1.7 mg/mL, P = 0.000; 5% vs 19%, P = 0.000), but significantly higher in treatment group vs ANP group (6.4 ±1.7 mg/mL vs 4.4 ±0.6 mg/mL, P = 0.020; 7% vs 5%, P = 0.048). The histological scores and W/D ratio were significantly decreased in treatment group vs ANP and control group.CONCLUSION: CQCQD might have a promotive effect on CTX concentration in pancreatic tissues of rats with ANP.

  16. 从中医经典探析卫气的生成与功能%Investigation on the Formation and Function of Defensive - qi from TCM Classics

    Institute of Scientific and Technical Information of China (English)

    刘伟; 宋霄霞

    2012-01-01

    Objective;Analyze the generation and transporation of body fluid of defensive - qi in depth. Methods;Explore the formation and function of defensive - qi based on the combination of "Yellow Emperor" and "Treatise on Febrile Diseases " as support. Results: The generation of Defensive - qi is the combined result of the triple energizer association. Defensive - qi has an important role on trans-poration of body fluid. Conclusion:Defensive - qi theory is not very perfect compared with other theory,which has not form a complete system and needs further analysis.%目的:深入探析卫气的生成与输布津液的功能.方法:以《黄帝内经》等中医经典理论为基础,以《伤寒论》的病证为根据,两者相互佐证来探讨卫气的生成与功能.结果:卫气的生成是三焦综合作用的结果,卫气在津液输布方面有重要作用.结论:卫气理论相对于其他理论还不是很完善,尚未形成一个完整的体系,需进一步探析.

  17. Clinical Observation on Insomnia Treated by Wei-Defensive Qi-Regulating and Brain-Strengthening Needling Technique

    Institute of Scientific and Technical Information of China (English)

    GAO Xi-yan; LI Xing-rui; MA Qiao-lin; ZHAO Xin-ji; SHAO Su-ju; WEI Yu-long; SUN Wei-xia; HANG Guo-qi

    2007-01-01

    In order to make a report on 90 cases of insomnia treated by the Wei-defensive qi-regulating and brain-strengthening needling technique,as a clinical subject of the multiple center,for assessing the preliminary standardized indications and operating methods and making an initial summary for writing the draft of the technique operation.Methods:By ratio of 1:1,the patients in conformity with the criteria were randomly divided into the experimental group and control group.In the experimental group,45 cases were treated with the Wei-defensive qi-regulating and brain-strengthening needling technique on Baihui (GV 20),Dazhui(GV 14),Shenmai(BL 62),Zhaohai(KI 6),plus ear points.In the control group,45 cases were treated with routine acupuncture on Sishencong(Ex-HN 1),Shenmen (HT 7),Sanyinjiao(SP 6),etc.The therapeutic effects in the two groups were observed and assessed in comparison.Results:The results showed cure in 15 cases.remarkable effect in 27 cases,effect in 42 cases,failure in 6 cases,and the total eriective rate in 94.4% in 90 cases of insomnia.In the three centers,the statistic management was performed based upon PSQI integral and showed significant difference(P<0.01),and no significant difference among various groups(P>0.01).Conclusion:The therapeutic effect in the treatment of insomnia by Wei-defensive qi-regulating and brain-strengthening needling technique is better than the control group and the therapeutic effect and methods in various centers are stable.without any deviation.

  18. Huang Qi Jian Zhong Pellet Attenuates TNBS-Induced Colitis in Rats via Mechanisms Involving Improvement of Energy Metabolism

    OpenAIRE

    Duan-Yong Liu; Chun-Shui Pan; Yu-Ying Liu; Xiao-Hong Wei; Chang-Man Zhou; Kai Sun; Ke He; Chong Li; Li Yan; Jing-Yu Fan; Chuan-She Wang; Toshifumi Hibi; Hong-Ning Liu; Jing-Yan Han

    2013-01-01

    Huang Qi Jian Zhong Pellet (HQJZ) is a famous Chinese medicine formula for treatment of various gastrointestinal tract diseases. This study investigated the role of HQJZ in 2,4,6-trinitrobenzene sulfonic acid- (TNBS-) induced colitis and its underlying mechanism. Colonic mucosal injury was induced by TNBS in the Sprague-Dawley rats. In the HQJZ treatment group, HQJZ was administered (2 g/kg) for 14 days starting from day 1 after TNBS infusion. Colonic mucosal injury occurred obviously 1 day a...

  19. A new 2-(2-phenylethyl)chromone derivative in Chinese agarwood 'Qi-Nan' from Aquilaria sinensis.

    Science.gov (United States)

    Yang, De-Lan; Wang, Hao; Guo, Zhi-Kai; Dong, Wen-Hua; Mei, Wen-Li; Dai, Hao-Fu

    2014-01-01

    Phytochemical analysis of the high quality Chinese agarwood 'Qi-Nan' originating from Aquilaria sinensis (Lour.) Glig led to the isolation of a new 2-(2-phenylethyl)chromone derivative, qinanones G (1), and four known 2-(2-phenylethyl)chromones (2-5). Their structures were elucidated by spectroscopic techniques (UV, IR, 1D and 2D NMR) and MS analyses. The NMR data of chromones 1-3 were first reported, and chromones 2 and 3 showed weak inhibitory activity against acetylcholinesterase.

  20. A new 2-(2-phenylethyl)chromone glycoside in Chinese agarwood "Qi-Nan" from Aquilaria sinensis.

    Science.gov (United States)

    Shao, Hang; Mei, Wen-Li; Kong, Fan-Dong; Dong, Wen-Hua; Li, Wei; Zhu, Guo-Peng; Dai, Hao-Fu

    2017-01-01

    A new 2-(2-phenylethyl)chromone glycoside, 2-[2-(4-glucosyloxy-3-methoxyphenyl)ethyl]chromone (1), was isolated from the high-quality Chinese agarwood "Qi-Nan" originating from Aquilaria sinensis (Lour.) Glig. The structure including the absolute configuration of the sugar moiety was elucidated by spectroscopic techniques (UV, IR, 1D and 2D NMR), MS analysis, PMP-labeling HPLC analysis methods, as well as comparison with literature data. To the best of our knowledge, it is the first time that chromone glycoside was discovered in agarwood, or even in the whole Aquilaria plants.

  1. JinQi-Jiangtang tablet, a Chinese patent medicine, for pre-diabetes: a randomized controlled trial

    OpenAIRE

    Hu Jing; Wang Xuemei; Li Xiantao; Wang Baohe; Wang Hui; Song Yuzhen; Zhang Junhua; Shang Hongcai; Guo Liping; Ren Ming; Cao Hongbo; Wang Dehui; Chen Jianzong; Li Shuanglei; Chen Liming

    2010-01-01

    Abstract Background Pre-diabetes is a growing health concern where a large percentage of these patients develop full type 2 diabetes. Effective interventions on pre-diabetes can prevent or delay the occurrence or development of diabetes. Pharmaco-dynamics and pre-clinical of JinQi-Jiangtang tablets (JQJT) suggest that it could be benefit for pre-diabetes. Methods/Design Randomized controlled trial (RCT) is implemented in this study. The study term is 24 months (12 months for intervention and ...

  2. "气"概念几个层次意义的分殊%A differentiation of the meaning of "qi" on several levels

    Institute of Scientific and Technical Information of China (English)

    李存山

    2008-01-01

    In Chinese philosophy,although the concept of "qi" has numerous meanings,it is not completely without order or chaotic.Generally speaking,"qi"has several different levels of meanings,such as in philosophy,physics,physiology,psychology,ethics,and so on.On the philosophical level,"qi" is similar to "air," and it is essentially similar to the "matter-energy" or "field" in physics,which refers to the origin or an element of all things in the world.It is from this point that the meanings of "qi" in physiology,psychology,ethics as well as aesthetics are derived.This paper analyzes the meanings of "qi" on five levels and seeks to clarify misunderstandings about "'qi," such as its alleged pan-vitalistic,conscious and pan-ethical characters.%中国哲学的"气"概念虽然含义极广,但并非毫无条理的混沌.大致说来,"气"概念有物理、生理、心理、伦理、哲理等几个层次的含义.哲理意义的"气"是指作为世界万物之本原或元素的"气",它可以化生万物,其本身与物理意义的"气"相通,而生理、心理、伦理乃至文论、美学等意义的"气"都由此衍生而来.这种分析有助于澄清对"气"概念的"泛生命性"、"有知觉"和"泛伦理性"等的误解.

  3. [Analysis and comparison of theories of circulation of blood and qi in both eastern and western ancient medicines].

    Science.gov (United States)

    Wang, Tai

    2014-09-01

    In ancient Egypt, the theory of circulation of blood and qi was preliminarily established on the basis of cadaver dissection, gradually revised and improved following the progress of anatomy and physiology. However, the "Meridian Theory" of circulation of blood and qi in Chinese medicine had never been established on the basis of anatomical and physiological studies. Thus a suspicion was aroused, "whether the meridians really exist, or artificially assumed by imagination"? Therefore, in recent one half of a century, numerous scholars at home and abroad spent countless financial capacities and human power to study the essence of Meridians in order to find their material or substantial evidence, but with no breakthrough obtained. Nevertheless, in the 70th of the last century, studies on mechanisms of acupuncture analgesia and acupuncture anesthesia won an undoubtedly good result. Hence, the therapeutic effect of acupuncture on pain control was admitted by the "Consensus Statement on Acupuncture" at an international meeting held by NIH in Dec. 1997. Then the old Chinese acupuncture won an international acceptance and application. Therefore, the investigation of mechanism of acupuncture analgesia set up a positive model for future scientific researches on acupuncture mechanisms and essence of Meridians, as well as on other Chinese medical theories.

  4. Treatment of Pulmonary Fibrosis from Qi Deficiency%从气虚论治肺纤维化

    Institute of Scientific and Technical Information of China (English)

    郑建; 朱雪; 王丽芹; 杨景青; 李莹莹; 郭俊美; 张伟

    2013-01-01

    肺纤维化是临床的疑难重症之一,中医药在治疗肺纤维化中发挥了其独特的优势.以中医基础理论为依据,从肺纤维化的病机出发,深入剖析气虚与肺纤维化的关系,证明气虚在肺纤维化发生、发展中的重要作用,为临床诊疗提供坚实的理论基础.%Pulmonary fibrosis is one of the difficult and severe diseases in clinic; in recent years,Chinese medicine has played its unique advantages in the treatment of pulmonary fibrosis.Based on the basic theory of traditional Chinese medicine,from the pathogenesis of pulmonary fibrosis,this paper analyzes the relation between qi deficiency and pulmonary fibrosis deeply,and demonstrates the important role of qi deficiency in the development of pulmonary fibrosis,providing a solid theoretical foundation for the clinical diagnosis and treatment.

  5. The influences of Chan-Chuang qi-gong therapy on complete blood cell counts in breast cancer patients treated with chemotherapy.

    Science.gov (United States)

    Yeh, Mei-Ling; Lee, Tsoy-Ing; Chen, Hsing-Hsia; Chao, Tsu-Yi

    2006-01-01

    After surgery, breast cancer patients are offered adjuvant chemotherapy to avoid cancer cell spread. During chemotherapy process, neutrophils could fall relatively, and side effects could spike to the peak. Therefore, the medical care personnel should prevent the progression of the side effects. This study aimed to examine the effects of Chan-Chuang qi-gong therapy on complete blood counts in breast cancer patients treated with chemotherapy. This study used a quasi-experimental design. The experiment group (n = 32) received a 21-day Chan-Chuang qi-gong therapy, whereas the control group (n = 35) did not. White blood cells, platelet, and hemoglobin were measured on the day before chemotherapy and on days 8, 15, and 22 during chemotherapy. According to this study, there were significant differences in white blood cells (F = 115.76, P qi-gong therapy may decrease leukopenia in breast cancer patients treated with chemotherapy. It is recommended conducting more studies on qi-gong and then introducing it in clinical nursing practice at an appropriate time to promote quality of nursing care and quality of patient life.

  6. Effects of San Qi on Gastric Secretion and Protective Factors of Gastric Mucosa in the Rat with Precancerous Lesion of Stomach

    Institute of Scientific and Technical Information of China (English)

    石雪迎; 赵凤志; 戴欣; 董秀云; 方杰; 杨会敏

    2003-01-01

    @@ In the model rat with precancerous lesion of stomach induced by the combined method of insertion of a spring into the pylorus and high salt hot paste, effects of San Qi (三七 Radix Notoginseng) on gastric secretion and protective factors of stomach were investigated.

  7. Danggui Buxue Decoction Being a Prescription of Replenishing Qi%当归补血汤可作为补气之方

    Institute of Scientific and Technical Information of China (English)

    沈耿杨; 黎同明

    2012-01-01

    历版教材均认为当归补血汤具有补气生血的功效而将其作为补血方剂的代表,笔者通过查阅大量文献,从该方的功效入手,探讨“血为气之母”的理论,结合当归补血汤的源流、衍化发展及临床应用现状,提出当归补血汤补血可,补气亦可,血虚、气虚皆可应用,不必拘于补血功效.%All the textbooks of Chinese Medicine consider that Danggui Buxue Decoction can replenish Qi to generate blood and represent it as the blood-replenishing prescription. The author investigates the theory of "blood is mother of qi" from the effect of this prescription by searching many literatures and combines its origin, developing, present situation of clinical application to propose that Danggui Buxue Decoction can be a prescription of replenishing qi. So this prescription can be the treatment of qi deficiency and blood deficiency.

  8. Somatosensory Nerve Fibers Mediated Generation of De-qi in Manual Acupuncture and Local Moxibustion-Like Stimuli-Modulated Gastric Motility in Rats

    Directory of Open Access Journals (Sweden)

    Yang-Shuai Su

    2014-01-01

    Full Text Available The aim of this study was to reveal the somatosensory nerve fibers mediated generation of De-qi in manual acupuncture stimuli (MAS and local moxibustion-like stimuli (LMS. The effects of strong and slight MAS, as well as 41°C, 43°C, and 45°C LMS at ST36 and CV12 on gastric motility were observed in rats. Gastric motility was continuously measured by an intrapyloric balloon, and the average amplitude, integral, and frequency of gastric motility during LMS were compared with those of background activity. Gastric motility was facilitated by MAS and LMS at ST36 and inhibited at CV12. The modulatory effects induced by strong MA with potent De-qi (needle grasp feeling were markedly higher than those by slight MA with mild De-qi sensation (P<0.05. The nociceptive 43°C and 45°C LMS, rather than nonnociceptive 41°C LMS, produced significant regulatory effects on gastric motility. Based on the afferent fibers activated in the present study, these results support the hypothesis that Aδ- and C-afferent fibers were more likely to be involved in the generation of De-qi sensation.

  9. Analysis on the Theoretical Origin of "Kidney Dominating the Reception of Qi"%"肾主纳气"理论源流探析

    Institute of Scientific and Technical Information of China (English)

    李文; 吴承玉

    2011-01-01

    目的:探究"肾主纳气"理论的历史源流.方法:梳理、归纳、整理春秋战国、秦汉、晋唐、宋元、明清几个时期,有关"肾主纳气"理论的发展轨迹.结果和结论:春秋战国时期属于该理论的萌芽阶段,汉代开创了补肾纳气法治疗喘证之先河,宋代明确提出"肾不纳气",明清时期该理论走向成熟.%Objective:To explore the historical origin of "kidney governing reception of qi" theory. Methods: According to several time periods: the Spring, Autumn and Warring States, Qin and Han dynasties, Jin and Tang dynasties, Song and Yuan dynasties, as well as Ming and Qing dynasties, this article explored theoretical development track of" kidney governing reception of qi ". Results and conclusion: The Spring, Autumn and Warring States period was the infancy stage of this theory and the method of treating dyspnea by "tonifying kidney to hold qi" was initiated during Han dynasty. The term "kidney failing to receive qi" was put forward in Song dynasty, and became mature during Ming and Qing dynasties.

  10. 扣子七中人参皂苷的HPLC-MS-MS方法研究%Research of ginsenosides in Kou zi qi using HPLC-MS-MS

    Institute of Scientific and Technical Information of China (English)

    邹坤; 刘朝霞; 朱姝; 蔡少青; 小松かつ子

    2004-01-01

    Aim To analyze the ginsenosides in Kou zi qi (rhizomes of Panax japonicus C.A. Mey. var. major (Burkill) C.Y.Wu et K. M. Feng), and to supply evidences for chemotaxanology of Panax species and clinical uses of Kou zi qi. Methods The ginsenosides were isolated by HPLC, then the positive- and negativeion API-MS/MS of constituents collected from HPLC were measured. Results Eight ginsenosides were identified as ginsenoside Re, ginsenoside Ro, chikuseksusaponins IV, IVa, notoginsenoside R2, ginsenosides Rb1 , Rc and Rd, respectively, based on comparison of retention time with those of standards by HPLC, and analysis on their API-MS/MS data. Ginsenoside Ro and chikuseksusaponin IVa are the major components of Kouzi qi. Conclusion This plant had a close relationship to P. stipuleanatns, P. zinginensis and P .japonicns var major; a relatively remote relationship to P. ginseng and P. quinquefolins, in a view of chemotaxanology. Ginsenoside Ro and chikuseksusaponin IVa might be the anti-inflammatory constituents of Kou zi qi.

  11. Effect of Bu-Zhong-Yi-Qi-Tang on deficiency of N-glycan/nitric oxide and islet damage induced by streptozotocin in diabetic rats

    Institute of Scientific and Technical Information of China (English)

    Xiao-Qiu Liu; Ling Wu; Xue-Jun Guo

    2009-01-01

    AIM: To investigate the effect of Bu-Zhong-Yi-Qi-Tang (Decoction for Reinforcing Middle Jiao and Replenishing Qi) on deficiency of N-glycan/nitric oxide (NO) and islet damage induced by injecting two medium doses of streptozotocin (STZ). METHODS: Diabetes was induced by intraperitoneal injection of STZ at 55 mg/kg on day 1 and day 8. Islet damage was evaluated using a scoring system. Nitrite, nitrate, α-mannosidase and amylase activities were measured by colorimetry. N-glycan patterns of amylase were determined with lectin [ConA, pisum sativum agglutinin (PSA), peanut agglutinin (PNA), and lens culinaris agglutinin (LCA)] affinity precipitation method. RESULTS: Severe islet necrosis and mild islet atrophy were observed in diabetic rats. The number and size of islets, the activities of α-mannosidase, amylase and nitrite were decreased, while the binding of PNA and LCA to amylase was increased. All of which were improved after treatment with Bu-Zhong-Yi-Qi-Tang. Islet damage was significantly correlated with nitrite, nitrate, α-mannosidase, amylase and the binding of LCA, PNA, and PSA to amylase. PNA, and PSA to amylase.CONCLUSION: STZ- induced i s let damage i s related to N-glycan def iciency in proteins by blocking α-mannosidase activity and no deficiency, accumulation of unfolded proteins, and endoplasmic reticulum stress and activation of cellular signals, all of which are improved after treatment with Bu-Zhong-Yi- Qi-Tang.

  12. 张锡纯论治气病的创新之处%Zhang Xi-chun Treatment Based on Syndrome Differentiation of Qi Disease

    Institute of Scientific and Technical Information of China (English)

    沈凌波

    2011-01-01

    Qi disease is a very important part of the clinic theories and experiments of ZHANG Xichun, a famous physician lived by the early years in Republic Of China, which mainly includes Great Qi, Vital Qi, Chong Qi and gynecological diseases etc. He gives many original advices of thories, treatment thoughts and effective prescriptions on these subjects. There are several case records which have made great sense to direct and inspire TCM clinic.%气病是民国初年著名医家张锡纯的临床理论和经验的重要组成部分,主要包括大气论、元气论、冲气论以及从冲脉论治妇科疾病等方面,其中多有创新之处,不落前人案巢,结合自身丰富的临床经验,分别提出了相应的治疗思路和措施,创制或创新了许多行之有效的方剂,并列举了多数医案,对后世临床有较大的指导和启发意义.

  13. Medical Case Literature Analysis of Clinical Characterization on Pectoral Qi Insufficiency Syndrome%宗气不足证临床表征医案文献分析

    Institute of Scientific and Technical Information of China (English)

    杨燕; 彭锦; 胡镜清; 陈亦辉

    2015-01-01

    Objective To identify the common clinical symptoms and signs of pectoral qi insufficiency syndrome;To provide evidence for its clinical treatment.Methods By retrieving 129 medical cases related to pectoral qi insufficiency syndrome in CNKI from January 1954 to October 2013 and Wanfang Database from January 1985 to October 2013, the authors made a statistical analysis of the symptoms and signs in medical cases related to pectoral qi insufficiency syndrome and elementarily generalized the common clinical characterization on pectoral qi insufficiency syndrome under the guidance of the TCM specialists.Results The cardinal syndromes of common clinical manifestation on pectoral qi insufficiency syndrome were shortness of breath and panting on exertion. The concomitant syndromes were pale or dim complexion, lassitude of spirit, lack of strength, shortage of qi and disinclination to talk, inability to sleep, dizziness, dizzy vision, etc. And it commonly superimposed failing to circulation qi-blood of cardiopulmonary as oppression in the chest, chest pain, palpitations, cyanosis, cough, etc, dysfunction of the spleen in transportation and transformation as torpid intake, sloppy stool, abdominal distension, and impairment of qi transformation due to Yang deficiency as cold limbs, fear of cold, edema, inhibited urination, and dry mouth.Conclusion The authors summarized cardinal syndrome, concomitant syndromes and superimposed symptoms on pectoral qi insufficiency syndrome from reported medical cases, which can provide scientific basis for normalizing the clinical diagnosis and treatment and interpreting the scientific connotation of pectoral qi insufficiency syndrome.%目的:了解宗气不足证临床常见症状、体征,为其临床诊治提供依据。方法通过检索中国期刊全文数据库(CNKI)1954年1月-2013年10月及中国学术期刊数据库(万方数据)1985年1月-2013年10月所收录期刊中129则宗气不足医案,将医案中所含有的症

  14. Discussion of Etiology,Syndrome and Treatment of Metrorrhagia and Metrostaxis from Qi and Blood%从气血论崩漏病因证治

    Institute of Scientific and Technical Information of China (English)

    王莉莉; 夏天; 许扬

    2016-01-01

    Metrorrhagia and metrostaxis are common and frequently-occurring disease in blood syndrome of gynecology,whose etiology and pathogenesis are always attributed to deficiency,heat and blood stasis. The deficiency of both Qi and blood leads to inability of controlling and insecurity of the thoroughfare and con-ception vessels,which furthermore leads to Qi collapse and results in bleeding. Fire harasses Xuehai,or causes frenetic movement of blood,or burns veins and collaterals,all of which can lead to insecurity of the thoroughfare and conception vessels and finally result in metrorrhagia and metrostaxis. Blood stasis blocking in uterus can cause blood failing to circulate in the vessels and metrorrhagia and metrostaxis ,which were mainly related to Qi deficiency,blood heat and blood stasis caused by bleeding. The treatment should focus on regulating the Qi flowing to stop bleeding and controlling the thoroughfare and conception vessels. In or-der to stop bleeding,Qi should be tonified for patients with Qi deficiency,Qi should be ascended up for pa-tients with Qi collapse,heat should be cleared for patients with blood heat,stasis should be dispersed for patients with blood stasis. When the bleeding is stopped ,Qi and blood can be nourished through reinforcing Qi to strengthen spleen,nourishing liver and kidney,then the blood will be abundant and the normal period-ic changes of menstrual cycle will recover.%崩漏为妇科“血证”的常见病、多发病,其病因病机多责之虚、热、瘀。气血亏虚,则统摄无力,冲任不固;甚则气虚下陷,血随气下;火扰血海,或破血妄行,或热灼伤脉络,致使冲任不固,发为崩漏;瘀血阻滞冲任胞宫,血不归经,发为崩漏,故其病因多责之气虚、血热、出血致瘀。治疗上应时时不忘调气止血,固护冲任,气虚者补之,气陷者升之,血热者清之,血瘀者化之,以迅速止血为目的;血止后,可通过益气健脾、

  15. Treatment of Motor Neuron Disease with Qi-invigorating Herbs—— A Report of 31 Cases

    Institute of Scientific and Technical Information of China (English)

    覃小兰; 杨志敏; 何德平; 刘旭生; 陈红霞; 黄燕; 张文青

    2002-01-01

    @@ The motor neuron disease (MND) refers to a group of progressive diseases with unknown reasons, which attacks the cells of the anterior horn of the spinal cord, the motor nuclei of the brain stem cranial nerves and the pyramidal cells of the cerebral motor cortex. It is characterized in clinic by atrophy of the muscles, myasthenia and even death due to paralysis of the respiratory muscle. Currently, there is still no any effective cure for this illness. 50-70% of the victims will die in 3 to 5 years, and the survival time for those with brain stem injuries is no more than two years.1 Since 1996, the authors have treated 31 cases of motor neuron disease with large dosage of qi-invigorating drugs in accordance with Prof. Liu Mocai's experience, and obtained certain therapeutic effects. A report follows.

  16. Effect of Reinforcing Qi and Moistening Intestine Oral Liquid on Anorectal Manometry of Asthenia Type Constipation Patients

    Institute of Scientific and Technical Information of China (English)

    2000-01-01

    Objective: To study the change of anorectal manometry in asthenia type constipation patients and effect of reinforcing Qi and moistening intestine oral liquid (RQMI) on it. Methods: The total of 135 cases were divided into healthy group, RQMI treated group, Maren pill (MRP) treated group and prepulsid (PPS) treated group, their anal maximal voluntary squeez pressure, rectoanal contraction reflex, rectoanal inhibitory reflex, defecation reflex, rectal volume sensory threshold and rectal maximal tolerable volume were observed. Results: The rectal sensory function of patients weakened obviously and anal sphincter reactivity reduced as compared with those of healthy person (P<0.01), and both were improved by RQMI treatment (P<0.05). Conclusion: RQMI is superior to MRP and prepulside in improving anorectal dynamic abnormality in constipation patient of asthenia type.

  17. Turo (Qi Dance Training Attenuates Psychological Symptoms and Sympathetic Activation Induced by Mental Stress in Healthy Women

    Directory of Open Access Journals (Sweden)

    Hwa-Jin Lee

    2009-01-01

    Full Text Available Vagal withdrawal and sympathetic overactivity accompany various types of stress. Qi training is reported to reduce sympathetic hyper-reactivity in a stressful situation. Turo, which is a type of dance that uses the Meridian Qi System, may reduce the psychological symptoms induced by an imbalance of the autonomic nervous system (ANS. We observed whether Turo training alters psychopathological and psychological symptoms using the Symptom Checklist 90-Revision (SCL-90-R and examined whether it attenuates the stress response to mental stress in healthy adolescent females using the power spectrum analysis of heart rate variability (HRV. Twenty-one subjects received Turo training and 27 subjects were trained with mimicking movements. The SCL-90-R was measured before and after the 2-month training period. Heart rate (HR, total power (TP and the LF/HF ratio of HRV were compared between the Turo and control groups during and after mental stress. The somatization and hostility subscales of the SCL-90-R of the Turo group were significantly lower than those of the control group after 2 months. The increases in HR and the LF/HF ratio of HRV induced by the stress test were significantly lower in the Turo group than in the control group. The TP of the Turo group was significantly higher than that of the control group. The psychological symptoms and sympathetic activation induced by the artificial stress were significantly reduced by the Turo training. These findings suggest that Turo training can play a critical role in attenuating psychological symptoms and stress-induced sympathetic activation.

  18. JinQi-Jiangtang tablet, a Chinese patent medicine, for pre-diabetes: a randomized controlled trial

    Directory of Open Access Journals (Sweden)

    Hu Jing

    2010-03-01

    Full Text Available Abstract Background Pre-diabetes is a growing health concern where a large percentage of these patients develop full type 2 diabetes. Effective interventions on pre-diabetes can prevent or delay the occurrence or development of diabetes. Pharmaco-dynamics and pre-clinical of JinQi-Jiangtang tablets (JQJT suggest that it could be benefit for pre-diabetes. Methods/Design Randomized controlled trial (RCT is implemented in this study. The study term is 24 months (12 months for intervention and 12 months for follow up. Participants are recruited from four cities of China: Beijing, Tianjin, Xi'an and Nanning. Four hundred participants are randomized to treatment group (JQJT tablets and control group (Placebo; two hundred participants each. People being included in this study must have been diagnosed as pre-diabetes via western medicine criteria and traditional Chinese medicine (TCM criteria. The end-point indexes include: incidence of diabetes mellitus and reversion rate. Primary outcome indexes include: oral glucose tolerance test; insulin releasing test; glycosylated hemoglobin (HA1c. Secondary outcome indexes include: score of the Short Form 36 Health Survey Questionnaire (SF-36; score of TCM symptoms; blood lipid test. Indexes of safety include: general medical examination; blood and urine regular test; electrocardiogram (ECG, liver function (ALT and renal function (BUN, Creatinine test; record of adverse event, such as headache, faint, etc. Qualitative control will be implemented and a number of standard operating processes (SOPs will be formed throughout the study: laboratory quality control measures; compliance control for researchers and participants; researcher training before study; supervision; investigational drug management and others. Discussion The aim of this study is to evaluate the effectiveness and safety of JinQi JiangTang (JQJT tablets for the treatment of patients with pre-diabetes. Trial registration Chinese clinical trials

  19. “大气一转其气乃散”临床应用探析%Clinical Analysis of the Theory about Dissipation of Pathogenic Factor Due to Normal Running of Vital QI

    Institute of Scientific and Technical Information of China (English)

    林玩福; 刘龙

    2011-01-01

    文章根据“大气一转,其气乃散”的原则,指出大气当是气机正常流动的一种状态,并从上焦之宗气、中焦之脾胃中气,下焦之肾中元气,以及阴阳交接的厥阴肝气四方面详细论述,提出运转大气不仅是治疗水气病的重要原则,对于现代临床中多种疾病的治疗也有重要的指导意义.%The paper based on theory of the expound of the theory of dissipation of pathogenic factor due to normal running of vital QI, indicated that the normal running of vital QI can maintain the healthy state of the body, and the paper discussed this theory from four opinions which ZongQi, ZhongQi, KindeyQi and liver-Qi. We draw the conclusion that normal running of vital QI is not only a normal therapeutic rule of water-related disease, but an important guidance for other clinical diseases.

  20. 6 June 2012 - Chinese Nanjing University President J.Chen in the ATLAS visitor centre with Member of the ATLAS Collaboration I. Wingerter and International Relations Office Adviser E. Tsesmelis. M. Qi, Nanjing University and ATLAS Collaboration, accompanies the delegation.

    CERN Multimedia

    Maximilien Brice

    2012-01-01

    6 June 2012 - Chinese Nanjing University President J.Chen in the ATLAS visitor centre with Member of the ATLAS Collaboration I. Wingerter and International Relations Office Adviser E. Tsesmelis. M. Qi, Nanjing University and ATLAS Collaboration, accompanies the delegation.

  1. Analyses of Composition and Structure on the Ancient Bronze Black Mirror“Hei-Qi-Gu”and Search Into the Treating Process of Its Surface Layer

    Institute of Scientific and Technical Information of China (English)

    范崇正; Suzuki Minoru; Inoue Miyoshi; Abe Tadahiro; Muraua Mitsuo; Asashi Ishikawa; 吴佑实; 李志超

    1994-01-01

    The Chinese ancient bronze black mirror"Hei-Qi-Gu"is famous for its black colour,brightsurface and anti-corroding property.In the present work,methods of SEM,IR,EPMA,Memhrane-XRD,and AFM were employed to detect the composition and structure of several pieces of Hei-Qi-Gu fragments.Itwas found that after casting,the surface of the bronze mirror was treated by a special process,and most ofCu was moved away while Sn and Si were rich in the surface layer.The oxides SnO2 and SiO2 on the surfacein a very small particle size are particularly stable and they protect the bronze alloy successfully.The surface layer and the transition layer have been dissected mainly,and some important informa-tion has been obtained.The special treating process of the mirror surface is searched and discussed.

  2. An Analyse of Qi Activity in Medical Treatment---Exploring the Running Laws of Qi Activity from the Ren Zhitang Medical Individuation to Enlightenment%由《任之堂医经心悟记》参究气机运转法

    Institute of Scientific and Technical Information of China (English)

    刘湘云

    2016-01-01

    整理分析《任之堂医经心悟记》一书中与气机运转相关的论述,以法天象地参人和、串起思维的珍珠链及大道至简、要言不烦三大方面为着力点参究中医的气机运转法则,体悟任老对运用气机运转法的广融会贯通与深入浅出,进而探讨气机运转法的涵义及临床运用。%Arranging as well as analysing some massage about qi activity from the book the Ren Zhitang Medical Individuation to Englightenment.And the theory of "observing the environment and the people",“string the pearls of thinking"and “explaining the truth with the simplest language”were expounded to explore the running laws of qi activity.It showed that Mr.Ren used the running laws of qi activity comprehensively,deeply andintricately in a simple way.It can explore the running laws of qi activity of traditional Chinese medicine as well as its clinical treatment.

  3. Therapeutic and recurrence-preventing effects of Qi-Replenishing and Blood-Activating Formula in rats with acetic acid-induced gastric ulcer

    Institute of Scientific and Technical Information of China (English)

    Guo-Rong Jiang; Hui-Nan Ge; Guo-Qiang Liang; Liang Zhou; Lu-Rong Zhang

    2016-01-01

    Objective: To explore the therapeutic and recurrence-preventing effects of Qi-Replenishing and Blood-Activating Formula in rats with acetic acid-induced gastric ulcer. Methods: A total of 138 SD rats were selected to make rat models with gastric ulcer induced by acetic acid (24 rats with sham operation served as sham operation group), and were randomly divided into model group (n=30), western medicine group (n=30), traditional Chinese medicine (TCM) group (n=24) and combination group (combined western medicine and TCM group, n=30). Western medicine group was gavaged with omeprazole in the morning and with iso-volumetric distilled water in the afternoon; TCM group and TCM sham operation group were gavaged with iso-volumetric distilled water in the morning and with Qi-Replenishing and Blood-Activating Formula in the afternoon;combination group was gavaged with omeprazole in the morning and with Qi-Replenishing and Blood-Activating Formula in the afternoon; sham operation group and model group were gavaged with iso-volumetric distilled water both in the morning and afternoon. Ulcer indexes and degree of mucosal degree in rats at different time points after gavage were observed. Twenty-eight days after gavage, interleukin (IL)-1β was given to induce ulcer recurrence so as to observethe recurrent severity and rate of ulcer in each group. Results: Compared with model group and western medicine group, treatment in combination group could prominently reduce the ulcer index of rats with peptic ulcer, and increase the healing rate and inhibition rate of peptic ulcer. After IL-1β-induced ulcer recurrence, combination group was significantly superior to modelgroup and western medicine group in ulcer recurrent rate [50% (3/6) vs. 100% (6/6)] and severity. Conclusions: Basic acid-suppression therapy combined with Qi-Replenishing and Blood-Activating Formula can effectually improve the ulcer healing quality and reduce ulcer recurrence.

  4. Study on the biofeedback effect and significance of getting qi in acupuncture%得气的生物反馈作用及意义的探讨

    Institute of Scientific and Technical Information of China (English)

    谷忠悦; 马铁明

    2009-01-01

    本文介绍了生物反馈疗法的基本概念及针刺得气与生物反馈的关系.针刺得气作为医患之间可控的生物信息反馈的指标,符合生物反馈疗法的技术操作要求.得气对患者的心理和生理功能具有双重调节作用,在纠正患者认知错误方面有语言暗示和行为暗示的治疗效果.以得气为指标治疗心理性疾病既符合中医理论又具有现代医学研究成果支撑,丰富了生物反馈疗法的内容和手段,可促进针灸医学向生理-心理-社会医学模式发展.%In this paper, the basic concept of biofeedback therapy and the relationship between getting qi in acupuncture and biofeedback are introduced. Getting qi in acupuncture as a controllable index of biological information feedback between the physician and the patient, meets the requirement of technique manipulation for biofeedback therapy. Arrival of qi has double regulative effects on the psychological and physiological functions of the patient, and has the effectiveness of the language suggestion and behavior suggestion in correcting the error in cognition of the patient. To take getting qi as an index in treatment of mental disorders conforms to theories of traditional Chinese medicine and is supported by modern medical research achievements, enriching contents and ways of biofeedback therapy and facilitating the development of acupuncture medicine towards biological-psychological-social medicine model.

  5. Assessment of effects of a formula used in the traditional Chinese medicine (Buzhong Yi Qi Wan) on the morphologic and osmotic fragility of red blood cells

    OpenAIRE

    Tania S. Giani; Paoli,Severo de; Presta,Giuseppe A.; Adalgisa I. Maiworm; Santos-Filho, Sebastião D.; Fonseca,Adenilson S.; Bernardo-Filho, Mario

    2007-01-01

    Buzhong Yi Qi Wan (BYQW) is a combination of some medicinal herbs widely used in traditional Chinese medicine to treat blood, spleen and stomach disorders. Morphometric analysis and osmotic fragility assay have been used to evaluate changes on membrane integrity of red blood cells. The aim of this work was to evaluate the effect of an aqueous BYQW extract on the morphology and osmotic fragility of red blood cells. Blood samples were treated with BYQW extract, quantitative/qualitative morpholo...

  6. Discussion on TCM Syndrome Differentiation and Treatment of Interstitial Lung Disease from the Deficiency of Pectoral Qi%从“宗气亏虚”探讨间质性肺疾病的中医辨治

    Institute of Scientific and Technical Information of China (English)

    景海卿; 付义

    2015-01-01

    间质性肺疾病是临床多发病及常见病,其发病机理不明,西医临床缺乏有效的治疗手段。而中医通过临床观察,发现本病与“宗气亏虚”有着密切关系,故可采用升补宗气治疗间质性肺疾病,且临床疗效显著。%Interstitial lung disease is a common disease.Its pathogenic mechanism is unclear, and the clinical Western medicine lacks of effective method.The pectoral qi assembles in chest, and is the pivot of respiratory, which promotes the movement of the lung.Through clinical observation, we found that the interstitial lung disease had a close relationship with the deficiency of pectoral qi, and the deficiency of pectoral qi throughout the disease.We treated interstitial lung disease with promoting and invigorating pectoral qi.Using the modified Shengxian decoction of Zhang Xichun, promoting and invigorating pectoral qi as well as invigorating and ascending yang qi, which can effectively alleviate symptom.The quality of life was improved.

  7. [Effects of Chinese herbs for replenishing qi and resolving stagnation on hypoxia-inducible factor-1alpha and vascular endothelial growth factor in granulation tissue of skin ulcers in rats with diabetes].

    Science.gov (United States)

    Que, Hua-fa; Zhu, Yuan-yin; Wang, Yun-fei; Zhang, Zhen; Xu, Jie-nan; Xing, Jie; Tang, Han-jun

    2007-03-01

    To explore the effects of Chinese herbs for replenishing qi and resolving stagnation on hypoxia-inducible factor-1alpha (HIF-1alpha) and vascular endothelial growth factor (VEGF) in granulation tissue of skin ulcers in rats with syndrome of blood stasis and qi deficiency. Diabetic rats with back full-thickness skin lesion and syndrome of blood stasis and qi deficiency were divided in to five groups: untreated group, basic fibroblast growth factor (bFGF)-treated group, Yiqi Huayu Recipe (a recipe for replenishing qi and resolving stagnation)-treated group, Yiqi Recipe (a recipe for replenishing qi)-treated group and Huayu Recipe (a recipe for resolving stagnation)-treated group, and another eight normal rats served as normal control group. Immunohistochemical method and image analysis were used to test the expressions of HIF-1alpha and VEGF in granulation tissue of skin ulcers in rats with diabetes. In the untreated group, the expression of HIF-1alpha was significantly increased and the expression of VEGF was significantly decreased as compared with those in the normal control group (PChinese herbs for replenishing qi and resolving stagnation can promote the wound healing in rats through reducing the expression of HIF-1alpha, accelerating the expression of VEGF in granulation tissue of skin ulcers in rats with diabetes and ameliorating the status of ischemia and hypoxia.

  8. [Analysis of 'treating different diseases by the same method' from aspect of theoretical research and clinical application of 'replenishing Qi and strengthening Shen'].

    Science.gov (United States)

    Dong, Jing-Cheng; Wu, Jin-Feng; Zhang, Hong-Ying; Gong, Wei-Yi; Liu, Bao-Jun; Xu, Hai-lin

    2013-05-01

    Treating different diseases by the same method is one of the most important characteristics in Chinese medicine, and as the main principle of treatment it has been widely applied in Chinese clinics. Its clinical effect is clear. The integration of 'differentiation of diseases' and 'differentiation of syndrome' should be the prerequisite and basis of 'treating different diseases by the same method'. Only if different diseases have the same syndrome, the same treatment can be used on them. Replenishing qi and strengthening Shen is a widely used method that carries out 'treating different diseases by the same method'. It is indicated that the method of 'replenishing qi and strengthening Shen' has preferable effects on many diseases. Part of its mechanism is associated with the improvement of function of neuro-endocrine-immune network, and therefore, it has the clinical effect of 'adjustment of the whole and improvement of the part' on partial disorders. Asthma, chronic obstructive pulmonary disease (COPD), uterine bleeding in puberty, anovulatory infertility, Kidney syndrome and aging, although they are attributed to different diseases and states, only if they have the syndrome of Shen deficiency, the principle of 'treating different diseases by the same method' and the method of 'replenishing qi 'and strengthening Shen' can be used effectively.

  9. 情志气机升降失调与眼科心身疾病%Qi Movement Disorders due to Emotions and Ophthalmic Psychosomatic Diseases

    Institute of Scientific and Technical Information of China (English)

    钟舒阳

    2013-01-01

    随着现代医学的不断发展,心身医学的概念已深入人心.作者认为各种精神情志因素导致的“气机升降失调”是心身疾病产生的主要病机,故就“气机升降失调”与眼科心身疾病发病中的关系,从几个方面进行了简单的论述.提出调畅情志和气机对于眼科治未病的重要性.%With the continuous development of modern medicine, the concept of psychosomatic medicine has been firmly established. The author believed that Qi movement disorders of the mental emotional factors are the pathogenesis of psychosomatic diseases. Therefore, in this article, the relationship between Qi-lifting disorders and ophthalmic psychosomatic disease was discussed. It is proposed regulating emotions and Qi movement is important for treating ophthalmology diseases.

  10. "Warming yang and invigorating qi" acupuncture alters acetylcholine receptor expression in the neuromuscular junction of rats with experimental autoimmune myasthenia gravis

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    Hai-peng Huang

    2016-01-01

    Full Text Available Myasthenia gravis is an autoimmune disorder in which antibodies have been shown to form against the nicotinic acetylcholine nicotinic postsynaptic receptors located at the neuromuscular junction. "Warming yang and invigorating qi" acupuncture treatment has been shown to reduce serum inflammatory cytokine expression and increase transforming growth factor beta expression in rats with experimental autoimmune myasthenia gravis. However, few studies have addressed the effects of this type of acupuncture on the acetylcholine receptors at the neuromuscular junction. Here, we used confocal laser scanning microscopy to examine the area and density of immunoreactivity for an antibody to the nicotinic acetylcholine receptor at the neuromuscular junction in the phrenic nerve of rats with experimental autoimmune myasthenia gravis following "warming yang and invigorating qi" acupuncture therapy. Needles were inserted at acupressure points Shousanli (LI10, Zusanli (ST36, Pishu (BL20, and Shenshu (BL23 once daily for 7 consecutive days. The treatment was repeated after 1 day of rest. We found that area and the integrated optical density of the immunoreactivity for the acetylcholine receptor at the neuromuscular junction of the phrenic nerve was significantly increased following acupuncture treatment. This outcome of the acupuncture therapy was similar to that of the cholinesterase inhibitor pyridostigmine bromide. These findings suggest that "warming yang and invigorating qi" acupuncture treatment increases acetylcholine receptor expression at the neuromuscular junction in a rat model of autoimmune myasthenia gravis.

  11. YiQiFuMai Powder Injection Ameliorates Cerebral Ischemia by Inhibiting Endoplasmic Reticulum Stress-Mediated Neuronal Apoptosis

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    Guosheng Cao

    2016-01-01

    Full Text Available YiQiFuMai (YQFM powder injection as a modern preparation derived from Sheng Mai San, a traditional Chinese medicine, has been widely used in the treatment of cardiovascular and cerebrovascular diseases. However, its neuroprotective effect and underlying mechanism in cerebral ischemia remain to be explored. The present study was designed to investigate the neuroprotective effect of YQFM on endoplasmic reticulum (ER stress-mediated neuronal apoptosis in the permanent middle cerebral artery occlusion- (MCAO- injured mice and the oxygen-glucose deprivation- (OGD- induced pheochromocytoma (PC12 cells. The results showed that single administration of YQFM (1.342 g/kg, i.p. could reduce the brain infarction and improve the neurological deficits and the cerebral blood flow (CBF after MCAO for 24 h in mice. Moreover, incubation with YQFM (100, 200, and 400 μg/mL could increase the cell viability, decrease the caspase-3 activity, and inhibit the cell apoptosis in OGD-induced PC12 cells for 12 h. In addition, YQFM treatment could significantly modulate cleaved caspase-3 and Bcl-2 expressions and inhibit the expressions of ER stress-related marker proteins and signaling pathways in vivo and in vitro. In conclusion, our findings provide the first evidence that YQFM ameliorates cerebral ischemic injury linked with modulating ER stress-related signaling pathways, which provided some new insights for its prevention and treatment of cerebral ischemia diseases.

  12. Huang Qi Jian Zhong Pellet Attenuates TNBS-Induced Colitis in Rats via Mechanisms Involving Improvement of Energy Metabolism.

    Science.gov (United States)

    Liu, Duan-Yong; Pan, Chun-Shui; Liu, Yu-Ying; Wei, Xiao-Hong; Zhou, Chang-Man; Sun, Kai; He, Ke; Li, Chong; Yan, Li; Fan, Jing-Yu; Wang, Chuan-She; Hibi, Toshifumi; Liu, Hong-Ning; Han, Jing-Yan

    2013-01-01

    Huang Qi Jian Zhong Pellet (HQJZ) is a famous Chinese medicine formula for treatment of various gastrointestinal tract diseases. This study investigated the role of HQJZ in 2,4,6-trinitrobenzene sulfonic acid- (TNBS-) induced colitis and its underlying mechanism. Colonic mucosal injury was induced by TNBS in the Sprague-Dawley rats. In the HQJZ treatment group, HQJZ was administered (2 g/kg) for 14 days starting from day 1 after TNBS infusion. Colonic mucosal injury occurred obviously 1 day after TNBS challenge and did not recover distinctively until day 15, including an increase in macro- and microscopic scores, a colonic weight index, a decrease in colonic length, a number of functional capillaries, and blood flow. Inverted intravital microscopy and ELISA showed colonic microcirculatory disturbances and inflammatory responses after TNBS stimulation, respectively. TNBS decreased occludin, RhoA, and ROCK-I, while increasing Rac-1, PAK-1, and phosphorylated myosin light chain. In addition, ATP content and ATP5D expression in colonic mucosa decreased after TNBS challenge. Impressively, treatment with HQJZ significantly attenuated all of the alterations evoked by TNBS, promoting the recovery of colonic injury. The present study demonstrated HQJZ as a multitargeting management for colonic mucosal injury, which set in motion mechanisms involving improvement of energy metabolism.

  13. Huang Qi Jian Zhong Pellet Attenuates TNBS-Induced Colitis in Rats via Mechanisms Involving Improvement of Energy Metabolism

    Directory of Open Access Journals (Sweden)

    Duan-Yong Liu

    2013-01-01

    Full Text Available Huang Qi Jian Zhong Pellet (HQJZ is a famous Chinese medicine formula for treatment of various gastrointestinal tract diseases. This study investigated the role of HQJZ in 2,4,6-trinitrobenzene sulfonic acid- (TNBS- induced colitis and its underlying mechanism. Colonic mucosal injury was induced by TNBS in the Sprague-Dawley rats. In the HQJZ treatment group, HQJZ was administered (2 g/kg for 14 days starting from day 1 after TNBS infusion. Colonic mucosal injury occurred obviously 1 day after TNBS challenge and did not recover distinctively until day 15, including an increase in macro- and microscopic scores, a colonic weight index, a decrease in colonic length, a number of functional capillaries, and blood flow. Inverted intravital microscopy and ELISA showed colonic microcirculatory disturbances and inflammatory responses after TNBS stimulation, respectively. TNBS decreased occludin, RhoA, and ROCK-I, while increasing Rac-1, PAK-1, and phosphorylated myosin light chain. In addition, ATP content and ATP5D expression in colonic mucosa decreased after TNBS challenge. Impressively, treatment with HQJZ significantly attenuated all of the alterations evoked by TNBS, promoting the recovery of colonic injury. The present study demonstrated HQJZ as a multitargeting management for colonic mucosal injury, which set in motion mechanisms involving improvement of energy metabolism.

  14. Effect of Da-Cheng-Qi Decoction on Pancreatitis-Associated Intestinal Dysmotility in Patients and in Rat Models

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    Jianlei Zhao

    2015-01-01

    Full Text Available The impairment of intestinal motility and related infectious complications are the predominant clinical phenomenon in patients with severe acute pancreatitis (SAP. We aimed to investigate the effects of Da-Cheng-Qi decoction (DCQD on the gastrointestinal injury in SAP patients and the potential mechanism involved in rats. DCQD was enema administered to 70 patients for 7 days in West China Hospital. Mortality and organ failure during admission were observed and blood samples for laboratory analysis were collected. We also experimentally examined plasma inflammatory cytokines in rat serum and carried the morphometric studies of the gut. Intestinal propulsion index and serum and tissue vasoactive intestinal peptide (VIP were also detected. Though DCQD did not affect the overall incidence of organ failure, it shortened the average time of paralytic intestinal obstruction and decreased the morbidity of infectious complications in patients with SAP. Compared with untreated rats, the DCQD lowered the levels of proinflammatory cytokine and decreased the mean pathological intestinal lesion scores. The VIP level in intestinal tissue or serum in DCQD group was obviously lowered and intestinal propulsion index was significantly improved. In conclusion, DCQD has good effect on pancreatitis-associated intestinal dysmotility in patients and in rat models.

  15. Cold and Spleen-Qi Deficiency Patterns in Korean Medicine Are Associated with Low Resting Metabolic Rate

    Science.gov (United States)

    Bae, Kwang-Ho

    2017-01-01

    Background. Korean medicine (KM) patterns such as cold, heat, deficiency, and excess patterns have been associated with alterations of resting metabolic rate (RMR). However, the association of KM patterns with accurately measured body metabolic rate has not been investigated. Methods. Data on cold (CP), heat (HP), spleen-qi deficiency (SQDP), and kidney deficiency (KDP) patterns were extracted by a factor analysis of symptoms experienced by 954 participants. A multiple regression analysis was conducted to determine the association between KM patterns and RMR measured by an indirect calorimeter. Results. The CP and SQDP scores were higher and the HP score was lower in women. The HP and SQDP scores decreased with age, while KDP scores increased with age. A multiple regression analysis revealed that CP and SQDP scores were negatively associated with RMR independently of gender and age, and the CP remained significantly and negatively associated with RMR even after adjustment for fat-free mass. Conclusions. The underlying pathology of CP and SQDP might be associated with the body's metabolic rate. Further studies are needed to investigate the usefulness of RMR measurement in pattern identification and the association of CP and SQDP with metabolic disorders.

  16. Woman Survival in Chinese Feudal Patrilineal Society: An Analysis of Song Lian's Destiny in Qi Qie Chenqun By Su Tong

    Directory of Open Access Journals (Sweden)

    Xuc Lin

    2009-05-01

    Full Text Available Article depicted woman’s difficulties in maintaining her life as well as her aggressiveness in the patrilineal society in Chinese feudal time. Article analyzed Song Lian’s bad fate. She was the main character of qi qie chenqun novel, written by Su Tong. Article analysis consisted of three parts. The first part described Song Lian’s background of life and her becoming a mistress. The second part indicated Song Lian’s attacking behavior to other woman because of defending her life. His third part analyzed some causes that made Song Lian did not survive in life. It can be concluded that the fact, Song Lian is able to be survive but she decides to be a mistress caused by both personal and o social reasons. Song Lian’s attacking other woman is caused by her anger representing her unsuccessful life. Principally, Song Lian’s failure in the feudal life is caused by her unsuccessful in becoming a respected woman. If she had been a respected woman, she would have also competed with other women in achieving a better life.      

  17. The effect of Bu-Zhong-Yi-Qi-Tang on epidermal melanocytes in ultraviolet B-irradiated mice

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Hae June [Korea Institute of Radiological and Medical Science, Seoul (Korea, Republic of); Kim, Hwan Sung; Park, Young Jong; Kim, Joong Sun; Moon, Chang Jong; Kim, Jong Choon; Bae, Chun Sik; Kim, Sung Ho [Chonnam National University, Gwangju (Korea, Republic of); Jo, Sung Kee [KAERI, Daejeon (Korea, Republic of)

    2008-09-15

    We induced the activation of melanocytes in the epidermis of C57BL/6 mice by UltraViolet B (UVB) irradiation and observed the effect of Bu-Zhong-Yi-Qi-Tang (BZYQT) on the formation, and decrease of UVB-induced epidermal melanocytes. C57BL/6 mice were irradiated by UVB 80 mJ/cm{sup 2} (0.5 mW/sec) daily for 7 days, and BZYQT was intraperitoneally or topically applied pre- or post-irradiation. For the estimation of change of epidermal melanocytes, light microscopic observation with dihydroxyphenylalanine (DOPA) stain was performed. Split epidermal sheets prepared from the ear of untreated mice exhibited 11-16 melanocytes/mm{sup 2}, and one week after UV irradiation, the applied areas show an increased number of strongly DOPA-positive melanocytes with stout dendrites. But intraperitoneal or topical treatment with BZYQT before each irradiation interrupted UVB-induced pigmentation and resulted in a marked reduction in the number of epidermal melanocytes as compared to radiation control skin. The number and size of DOPA-positive epidermal melanocytes were also significantly decreased in intraperitoneally injected or topically applicated group after irradiation with BZYQT at 3rd and 6th weeks after irradiation. The present study suggests the BZYQT as inhibitor of UVB-induced pigmentation and depigmenting agent.

  18. Material Base of in vivo Invigorating Qi and Enriching Blood of Bazhen Decoction by HPLC-ESI-MS

    Institute of Scientific and Technical Information of China (English)

    LI Wen-lan; BAI Jing; SUN Zhi; DU Juan; JI Yu-bin

    2012-01-01

    Objective To identify the in vivo metabolized chemical constituents in Bazhen Decoction(BZD)and to study the relationship between Siwu Decoction(SWD)and Sijunzi Decoction(SJZD)with BZD.Methods Analysis and comparison were carried out by HPLC-ESI-MS.Serum samples after ig administration of preparations such as SWD,SJZD,and BZD,with different ingredients were collected for analysis.Results Twenty-two components were detected after ig administration of BZD,and six of them were metabolites and others were original form of the components contained in BZD.The prototype constituents were atractylenolide Ⅰ,5-hydroxymethyl-furoic acid(5-HMFA),oxypaeoniflorin,atractylenolide Ⅲ,albiflorin,paeoniflorin,liquiritin,ferulic acid,ligustilide,and ginsenosides Rg1 and Rb1.The metabolized constituents were paeonimetabolin Ⅰ,glycyrrhetic acid monoglucuronide,glycyrrhetinic acid,and ginsenosides Rh1 and Rd.Conclusion The results also show that 5-HMFA,oxypaeoniflorin,albiflorin,paeoniflorin,ferulic acid,and ligustilide are common components absorbed into blood existing in both BZD and SWD,which are material base of enriching blood;Atractylenolide Ⅰ,atractylenolide Ⅲ,and liquiritin are common ingredients absorbed into blood existing in both BZD and SJZD,and they are material base of invigorating Qi.The results provide basic data for the further studies on the effective components,the effecting mechanism,and the quality control of BZD.

  19. Protective effect of the extract of Yi-Qi-Fu-Mai preparation on hypoxia-induced heart injury in mice

    Institute of Scientific and Technical Information of China (English)

    FENG Ya-Qian; JU Ai-Chun; LIU Chun-Hua; WANG Ting; YU Bo-Yang; QI Jin

    2016-01-01

    Yi-Qi-Fu-Mai (YQFM) is extensively used clinically to treat cardiovascular diseases in China.To explore the anti-hypoxia effect of the extract of YQFM preparation (EYQFM),the EYQFM (1.4,2.8,and 5.5 g·kg-1·d-1) was assessed for its heart-protective effect in a chronic intermittent hypoxia (CIH) animal model (oxygen pressure 7%-8%,20 min per day) for 28 days of treatment.Betaloc (0.151 6 g·kg-1·d-1) was used as a positive control.The histopathological analyses of heart in CIH mice were conducted.Several cardiac state parameters,such as left ventricular ejection fractions (EF),stroke volume (SV),expression of creatine kinase (CK),lactate dehydrogenase (LDH),superoxide dismutase (SOD),and malondialdehyde (MDA) were measured.The results showed that treatment with EYQFM markedly reversed swelling of the endothelial cells and vacuolization in the heart when compared with the model group.Further study demonstrated that EYQFM significantly improved ventricular myocardial contractility by increasing EF and SV.In addition,EYQFM inhibited the activity of CK,LDH,decreased the level of MDA and improved SOD activity.The results demonstrated that EYQFM significantly improved the tolerability of myocardium to hypoxia and ameliorated the cardiac damage in the CIH model.

  20. Effects of Chinese herbs capable of replenishing qi,nourishing yin and activating blood circulation and their compatibility on differentially expressed genes of ischemic myocardium

    Institute of Scientific and Technical Information of China (English)

    YIN HuiJun; GUO ChunYu; SHI DaZhuo

    2009-01-01

    This study was conducted to investigate the effects of Chinese herbs capable of replenishing qi,nourishing yin and activating blood circulation and their compatibility on differentially expressed genes of ischemic myocardium which were selected from differential expression profile we had established before,and to explore the underlying mechanism. The acute myocardial infarction (AMI) model was established by ligating the left anterior descending (LAD) coronary artery,then the model rats were randomly divided into the model group,the Metoprolol group,the replenishing qi nourishing yin (RN)group,the activating blood circulation (AB) group,and the replenishing qi,nourishing yin and activating blood circulation (RA) group. In addition,the normal group and the sham group were set up. The rats of medication groups were administered by intragastric gavage with corresponding drugs on the second day after operations,and the rats of the normal group and the sham group were given normal saline as the same time.Then the ischemic hearts were harvested on the 8th day after operation. The myocardial pathomorphological changes were observed under a light microscope. The mRNA changes of target genes such as COX5a and ATP5e were detected using Real-time fluorescence quantitative PCR (Q-PCR),and the activities of related enzymes were detected by colorimetric assay. The main results were as follows:the histological changes were observed by HE staining,and cardiocyte swelling,inflammatory cell infiltration and cytolysis were showed in regional ischemic myocardium of the model group,while the pathomorphological changes in all medication groups did not show obvious changes.Two genes related to energy metabolism,COX5a and ATP5e,were selected as the target genes which were down-regulated at the mRNA level in the medication groups. The activities of correlative functional enzymes also decreased in the RA group compared to that in the model group accordingly (P<0.05). The results indicated

  1. 极地适冷菌Pseudoalteromonas sp.QI-1产适冷蛋白酶发酵条件的优化%Optimization of cold-active protease production by polar psychrotrophic bacterium Pseudoalteromonas sp.QI-1

    Institute of Scientific and Technical Information of China (English)

    徐国英; 林学政; 王能飞; 朱启忠

    2011-01-01

    The culture conditions of polar psychrotrophic bacterium Pseudoalteromonas sp. QI-1 were optimized for the production of cold-active protease. The optimum fermentation conditions were determined as follows: optimal temperatures for growth and enzyme production were both at 5 ℃, inoculation volume was 1% ,and liquid volume was 10% at pH 5. Culture medium for protease production of strain QI-1 was also studied. Results showed that nitrogen source and carbon source preferred by protease production were bran and sodium acetate. 2% NaC1,10 mmol/L Mg2+ ,0.5% Tween-80 and 0.75% casein were suitable for the enzyme production. The orthogonal experiment design showed that the optimum medium (per liter) consisted of 5 g bran,2.5 g yeast extract,3 g casein,3 g MgCl2 ·6H20 and 1.5 g KCl. Under the optimum condition, the protease activity was up to 166. 20 U/mL and the yield of protease increased about 56%.%对极地适冷菌Pseudoalteromonas sp.QI-1产适冷蛋白酶的发酵条件进行优化.结果表明:菌株QI-1的最适生长和产酶温度均为5℃;最佳接种量为1%;发酵培养基的最适初始pH和最佳装样量分别为5和10%;盐度为2%时对菌株的生长和产酶最为有利;麸皮和醋酸钠分别为最佳N源和C源;添加0.75%酪蛋白时菌株QI-1胞外蛋白酶的活性最高;10 mmol/L Mg2+和0.5%Tween-80有利于产酶.正交试验结果表明:菌株Pseudoalteromonas sp.QI-1产蛋白酶较佳培养基配方(g/L)为麸皮5,酵母粉2.5,酪蛋白3,MgCl2·6H2O3,KCl 1.5;发酵液比酶活为166.20 U/mL,较优化前提高了约56%.

  2. Indicadores de Desenvolvimento em Crianças e Adolescentes com QI Igual ou Inferior a 70

    Directory of Open Access Journals (Sweden)

    Fernanda Santos SOUZA

    Full Text Available RESUMO: este estudo teve o objetivo de buscar indicadores de desenvolvimento em crianças e adolescentes com dificuldades para aprender, com QI igual ou inferior a 70 no teste WISC-IV (compatível com o valor delimitado para o diagnóstico de deficiência intelectual. Fundamentou-se na perspectiva histórico-cultural do desenvolvimento humano proposta por Vygotsky, especialmente no que se refere à distinção entre desenvolvimento real e potencial. Foram relatados estudos de caso com duas crianças. A coleta de dados ocorreu a partir de gravações em áudio de entrevistas semiestruturadas com os pais/responsáveis e com os profissionais da escola em que os participantes estavam matriculados, e gravações em vídeo das sessões de atendimento de um serviço de educação não formal que as crianças participavam regularmente. A análise de dados envolveu transcrição das entrevistas e elaboração de quadros com os modos de participação social e processos mentais superiores relatados, de cada criança/adolescente; exame das filmagens das sessões de atendimento, com transcrição e análise microgenética de episódios significativos. Os dados sugerem que, ao se enfatizar a busca de indicadores de desenvolvimento, pode-se obter uma visão abrangente de cada caso, de forma a contemplar, para além das limitações, as potencialidades das crianças e dos adolescentes.

  3. Modified Da-Cheng-Qi Decoction reduces intra-abdominal hypertension in severe acute pancreatitis: a pilot study

    Institute of Scientific and Technical Information of China (English)

    WAN Mei-hua; LI Juan; HUANG Wei; Rajarshi Mukherjee; GONG Han-lin; XIA Qing; ZHU Lin; CHENG Gui-lan; TANG Wen-fu

    2012-01-01

    Background Intra-abdominal hypertension (IAH) is a recognized prognostic marker for severity of severe acute pancreatitis (SAP) and has a strong impact on the clinical course of SAP.Previous studies indicate that a Da-Cheng-Qi Decoction (DCQD) is beneficial in the treatment of SAP.The purpose of this study was to evaluate the effect of modified DCQD on IAH in patients with SAP.Methods Between January 2008 and December 2008,42 patients from the West China Hospital were randomized into either the DCQD or control group (n=21 in each group).Mortality,intra-abdominal pressure (lAP),Acute Physiology and Chronic Health Evaluation II (APACHE II) score,C-reactive protein (CRP),oxygenation index,Balthazar CT score,rate of renal failure,decompression rate,intensive care unit (ICU) transfer rate,and length of hospital stay (LOS) were compared between the two groups.Results Compared to the control group,the modified DCQD treatment significantly decreased lAP (P <0.05) and APACHE Ⅱ (P <0.05) scores on days 4-8,CRP on day 8 (P <0.01 ),renal failure rate (P <0.05),and LOS (P <0.05).The oxygenation index was significantly improved in the DCQD group compared with the control group (P <0.05).No significant differences in the Balthazar CT score,shock rate,ICU transfer rate,or mortality occurred between the two groups.Conclusions The modified DCQD can effectively relieve IAH and decrease LOS for patients with SAP.Larger clinical trials are needed to confirm these findings.

  4. 张居正与戚继光关系论略%A Brief Study of the Relationship between Zhang Juzheng and Qi Jiguang

    Institute of Scientific and Technical Information of China (English)

    赵毅; 于宝航

    2013-01-01

    Since Longqing period in Ming Dynasty ,Zhang Juzheng ,senior grand secretary of Cabinet kept providing Qi Jiguang ,distinguished general of the times with consistent supports in terms of position ,du-ties and military affairs for 16 years .In early Wanli period ,during his power heyday ,Zhang ,under the name of the court ,continued to support Qi ,because of w hich the latter obtained a series of military victo-ries in Ji Town .Zhang favored Qi ,in one way ,was for Qi’s special talent for assisting his career develop-ment .On the other hand ,he also aimed to cultivate men of abilities for the country instead of seeking his own private purposes .With Zhang’s support ,Qi achieved his great ideals ,which made him venerate Zhang .But by no means did he try to flatter the senior official .In view of the times ,the harmonious rela-tionship between the“wise prime minister” Zhang and the“distinguished general” Qi ,showed that in the crisis of national defense ,some far-sighted persons from the civil service group attempted to share more power with the generals in spite of the atmosphere of “intellectual pursuits above material arts” .As a dis-tinguished general ,Qi happened to meet the opportunity ,thus got appreciated and promoted by Zhang .%张居正对戚继光的支持长达十六年之久,可谓一以贯之。自隆庆时期张居正就在职务、事权、军务等方面对戚继光给予支持。万历初年,张居正权力如日中天,得以用朝廷的名义继续支持戚继光,使其在蓟镇取得很多成绩。张居正重用戚继光,既是看中他的才能有助于自己的“相业”,也是为国家造养人才,并非结党,更不是希图贿赂。戚继光借助张居正的支持实现自己的理想,虽对张居正礼敬有加,但也绝非逢迎大僚、蝇营狗苟之辈。从时代背景来看,张居正与戚继光这对“贤相”与“名将”相得,是因为在国防危机的情况下,文官集团中的

  5. [Effects of Chinese herbs for replenishing qi and resolving stagnation on transforming growth factor-beta1 of skin ulcers in rats with diabetes].

    Science.gov (United States)

    Zhang, Zhen; Que, Hua-fa; Zhu, Yuan-ying; Wang, Yun-fei; Liu, Xiao-dong; Zheng, Pei-yong

    2007-07-01

    To explore the effects of Yiqi Huayu Recipe, a compound traditional Chinese herbal medicine for replenishing qi and resolving stagnation, on transforming growth factor-beta1(TGF-beta1) of skin ulcers in rats with diabetes. Sixty rats were randomly divided into six groups, Yiqi Huayu Recipe-treated group, Yiqi (replenishing qi) Recipe-treated group, Huayu (resolving stagnation) Recipe-treated group, basic fibroblast growth factor (bFGF) treated group, untreated group and normal control group. Diabetes was induced by peritoneal injection of streptozotocin and skin ulcers were made by surgery method in rats except for the normal control group. Then the rats were administered with different drugs respectively, and the expression of TGF-beta1 in granulation tissue of the skin ulcers was detected with the methods of Western blotting, image analysis and immunohistochemistry. The level of TGF-beta1 expression in the untreated group was lower than that in the normal control group (P<0.01); and the level of TGF-beta1 expression in the drug-treated groups was higher than that in the untreated group (P<0.01); and the TGF-beta1 expression in the Yiqi Huayu Recipe-treated group was higher than that in the Yiqi Recipe-treated group, Huayu Recipe-treated group and bFGF-treated group (P<0.05). The replenishing qi and resolving stagnation therapy can control the secretion of TGF-beta1 of the wound in the process of wound healing in the levels of gene and molecule.

  6. 疏肝解郁法治疗乳腺癌进展%Progress of Breast Cancer Treatment by Relieving Depression of the Liver-qi

    Institute of Scientific and Technical Information of China (English)

    华琼博; 郭勇

    2015-01-01

    Breast cancer is one of the most common malignant tumor in women.In our country,the incidence of breast cancer shows a rapidly upward trend which has become the female's highest morbidity of malignant tumors.Traditional Chinese medicine( TCM) is one of the important therapeutic method for treating breast cancer.TCM believes that stagnation of liver-qi is closely related to the forma-tion,progression and prognosis of Ru Yan,and it thinks highly of relieving depression of the liver-qi.A large number of ancient physi-cians and modern researches have confirmed the effects of it.In this paper,treating breast cancer by relieving depression of the liver-qi will be preliminarily explored.%乳腺癌是女性最常见的恶性肿瘤之一,在我国,乳腺癌的发病率呈现快速上升的趋势,已然成为女性恶性肿瘤发病率之首。中医药是治疗乳腺癌的重要方法之一,中医认为乳岩的发生、发展、预后与肝气郁结密切相关,中药治以疏肝解郁,疗效显著。大量古代医家和现代研究证实疏肝解郁对于乳腺癌的疗效。本文就疏肝解郁法治疗乳腺癌作初步探讨。

  7. Revisiting the flavor changing neutral current Higgs decays $H\\to q_i q_j$ in the Standard Model

    CERN Document Server

    Benitez-Guzmán, L G; López-Osorio, M A; Martínez-Pascual, E; Toscano, J J

    2015-01-01

    An exact calculation of the Higgs boson decays $H\\to q_i q_j$ mediated by flavor changing neutral currents is presented in the context of the Standard Model. Using up-to-date experimental data, branching ratios of the order of $10^{-7}$, $10^{-8}$, $10^{-8}$, and $10^{-15}$ are found for the $\\bar{b}s+\\bar{s}b$, $\\bar{b}d+\\bar{d}b$, $\\bar{s}d+\\bar{d}s$, and $\\bar{c}u+\\bar{u}c$ decay modes, respectively.

  8. 经气法时中医外治法及其应用探讨%Discussion and Application on the TCM External Treatment of "Meridian Qi Changes with Time"

    Institute of Scientific and Technical Information of China (English)

    谢胜; 张越; 周晓玲; 刘圆圆; 侯秋科

    2013-01-01

    External treatments of Traditional Chinese Medicine have advantages of rapid action and remarkable curative effect, however, to a certain extent, the further development of the treatment has been delayed by the imperfection of the theoretical system. Therefore, the authors put forward the concept of " meridian qi changes with time" on the basis of their years of clinical practice. The authors hold that the change of lunar years trend and the transition of host and guest climatic qi would affect the running of meridian qi in human body. We used this theory to adjust meridian qi, tonify deficiency and reduce excess according to time and qi running regulation to harmonize qi, blood, yin and yang, so as to adjust constitution.%中医外治法具有作用迅速、疗效显著等多种优点,但其理论系统的相对滞后,在一定程度上限制了该疗法的进一步发展.笔者在多年临证实践基础上,提出经气法时中医外治法的概念,认为不同年运及主客气的更替变化,对人体经气运行会产生影响.并根据此理论,针对人体经络所产生的相应气血运行变化及功能偏颇,应时而治,应时辰、运气规律而调经气,补虚泻实,达到和调气血阴阳,调体质之偏颇的目的.

  9. Assessment of Electromagnetic Interference with Active Cardiovascular Implantable Electronic Devices (CIEDs Caused by the Qi A13 Design Wireless Charging Board

    Directory of Open Access Journals (Sweden)

    Tobias Seckler

    2015-05-01

    Full Text Available Electromagnetic interference is a concern for people wearing cardiovascular implantable electronic devices (CIEDs. The aim of this study was to assess the electromagnetic compatibility between CIEDs and the magnetic field of a common wireless charging technology. To do so the voltage induced in CIEDs by Qi A13 design magnetic fields were measured and compared with the performance limits set by ISO 14117. In order to carry this out a measuring circuit was developed which can be connected with unipolar or bipolar pacemaker leads. The measuring system was positioned at the four most common implantation sites in a torso phantom filled with physiological saline solution. The phantom was exposed by using Helmholtz coils from 5 µT to 27 µT with 111 kHz sine‑bursts or by using a Qi A13 design wireless charging board (Qi‑A13‑Board in two operating modes “power transfer” and “pinging”. With the Helmholtz coils the lowest magnetic flux density at which the performance limit was exceeded is 11 µT. With the Qi‑A13‑Board in power transfer mode 10.8% and in pinging mode 45.7% (2.2% at 10 cm distance of the performance limit were reached at maximum. In neither of the scrutinized cases, did the voltage induced by the Qi‑A13‑Board exceed the performance limits.

  10. A Clinical Study on the Treatment of Chronic Pelvic Inflammation of Qi-stagnation with Blood Stasis Syndrome by Penyanqing Capsule (盆炎清胶囊)

    Institute of Scientific and Technical Information of China (English)

    SHEN Bi-qiong; SITU Yi; HUANG Jian-ling; SU Xiao-mei; HE Wei-tang; ZHANG Mao-wei; CHEN Qu-bo

    2005-01-01

    Objective: To observe the clinical efficacy of Penyanqing Capsule (盆炎清胶囊, PYQC) in treating pelvic inflammation of Qi-stagnation with blood stasis syndrome. Methods: The randomized, single blinded, parallel positive drug controlled method was adopted, with 82 patients assigned into two groups by envelop method. The 42 patients in the treated group received PYQC 3 times a day, 4 capsules each time taken orally; the 40 patients in the control group were given orally Fuyankang tablets (妇炎康片, FYKT) 3 times a day, 6 tablets each time. The therapeutic course for both groups was 2 months, and 2 courses of treatment were given successively to observe the comprehensive effect, changes of symptoms and signs before and after treatment. The effects of PYQC on hemorrheological character in part of the patients and on the pathogenetic chlamydia and mycoplasma were also observed. Results: The total effective rate in the treated group was 83.3 %, which was insignificantly different from that in the control group ( 77.5 %, P > 0.05 ).However, PYQC could significantly lower the hemorrheologic indexes in patients and showed definite influence on the pathogenetic chlamydia and mycoplasma. Conclusion: PYQC has good therapeutic effect in treating chronic pelvic inflammation of Qi-stagnation with blood stasis syndrome, and showed definite effect on chlamydia and mycoplasma.

  11. Effect of Chinese Herbs for Activating Blood Circulation,Removing Stasis and Supplementing Qi on the Circulating Endothelial Cells in Patients with Unstable Angina Pectoris

    Institute of Scientific and Technical Information of China (English)

    马丽红; 阮英茆; 焦增绵; 李晓惠

    2004-01-01

    Objective: To observe the effect and clinical significance of circulating endothelial cells (CEC) in the pathogenesis of coronary heart disease with unstable angina pectoris (CHD-UAP), and to explore the protective effect of Chinese herbs for activating blood circulation, removing stasis and supplementing Qi (CH) on CHD-UAP patient's CEC. Methods: Sixty patients with diagnosis of CHD-UAP confirmed and differentiated to be Qi-deficiency and blood stasis by TCM were randomly divided into two groups and treatime, with 1 month as one therapeutic course. The number of CEC in patients' blood circulation was counted before and after treatment. Besides, the number of CEC in 30 healthy persons was also counted for control.Results: The number of CEC in CHD-UAP patients was significantly higher than that in the healthy persons (P<0.01). After the patients were treated with CH, either TXL or HXTM, it significantly decreased (P<0.01)with insignificant difference between the two treated groups. Conclusion: CEC in CHD-UAP patients is severely damaged and endothelial function in disorder, Chinese herbs have protective effect on patients' CEC.

  12. Design of wireless charger based on QI protocol%基于QI协议的无线充电器的设计

    Institute of Scientific and Technical Information of China (English)

    曾维; 秦建波; 邓蕾; 胡男; 张玉竹

    2014-01-01

    通过对无线充电三种方式的研究,选择QI协议作为本设计的设计方式。主芯片选用了TI系列的无线充电芯片,用符合WPC1.1标准的无线电源发送器管理器bq500211a作为发射芯片,用符合Qi (WPC)标准的高度集成的次级侧直充式锂离子充电器bq51050b作为接收部分,完成了无线充电器的设计。%By study of three ways of wireless charger,the design of the application is based on QI protocol.TI's wireless charging chip is Selected as main chip .Using TI's bq500211a as the emission chip to meet the WPC1.1 standard of Wireless power transmitter manager,and Using TI’s bq51050b as the receiving part to meet the standard of lithium ion charger of highly integrated straight type secondary side,completed the wireless charger designs.

  13. 论藏象体系的天人气化和谐%Study on Harmonious Human-Environmental Relation of Visceral Manifestations System by Theory of Qi transformation

    Institute of Scientific and Technical Information of China (English)

    王慧峰; 严世芸

    2011-01-01

    天人相应是藏象体系气化研究的重要组成部分,"和"则是藏象体系天人气化关系的重要思想原则,本文从气化观出发,对藏象体系的天人气化和谐进行了初步的探讨,简要论述了保持天人气化和谐的必要性,以及藏象体系天人气化和谐的状态,并由此提出处理天人关系失和的基本原则,即顺应自然之气化规律,恢复脏腑气化运动本性和旺衰规律.%The theories of human - environmental relation is important part of study on visceral manifestations system. Harmoniousness is important principia of human - environmental relation of visceral manifestations system. Based on theory of Qi transformation, the studies is made about harmonious relation of human - environmental. The conclusion is that keeping harmonious relation of human - environmental is necessary. And the principia of treating unharmonious of human - environmental relation is comply with the rules of Qi transformation of nature.

  14. 壮医气血理论的理论基础与临床应用%Theoretical foundation and clinical application of the qi and blood theory of Zhuang Medicine

    Institute of Scientific and Technical Information of China (English)

    宋宁

    2013-01-01

    壮医认为气和血是构成人体和涵养生命的最基本物质,二者通过三道两路系统而循环流注全身,涵养机体组织,推动人体生理功能协调运行.气血宜动、宜衡,又相互资生,相依为用,气血平衡调畅,则人体健康;气血失衡,则产生疾病.气血理论是壮医核心理论,也是壮医重要的病机理论,对指导临床实践具有重要价值.文章阐述了壮医气血的概念、内涵及其关系,气血的生理功能、病理变化及病机特点,壮医气血理论的内容及其应用,提出平衡气血治则治法,初步建立壮医的理法方药体系.%Zhuang Medicine considered that qi and blood are the most basic elements which constitute human body and nourish life. Qi and blood circulate in the whole human body and nourish life which can promote physiological function by the system of three paths and two passages. Qi and blood should be better to move and keep harmony; both of them rely on each other. If they keep harmony, the body can keep health, or otherwise disharmony may result in some diseases. In this point, Qi and blood theory is the core of Zhuang Medicine which is the important pathogenesis theory and offers a significant guideline to the clinical practice. This paper described the definition, connotation and relationship between qi and blood in Zhuang Medicine. It also illustrated the physiological function, pathological changes and pathogenesis characteristics of qi and blood, as well as the content of Qi and blood theory and its applications. It also puts forward to the therapeutic principle and method of keeping balance between qi and blood, which has a preliminary establishment of the system of Zhuang Medicine in its theory, method, formula and herbs.

  15. Exploration and analysis of chronic urticaria treated with replenishing qi and nourishing blood to expel wind method%益气养血祛风法治疗慢性荨麻疹探析

    Institute of Scientific and Technical Information of China (English)

    闫学文

    2012-01-01

    Chronic urticaria is a common and frequently encountered disease in the department of dermatology. Chronic urticaria is usually induced by deficient qi and blood invasion by pathogenic wind in Traditional Chinese medicine. The curative effect of chronic urticaria with replenishing qi and nourishing blood to expel wind method is satisfactory.%慢性荨麻疹是皮肤科常见病、多发病,中医认为病因是气血虚弱,风邪外邪引起;使用益气活血祛风法治疗取得满意疗效.

  16. Brief Analysis of the Application of Mudanpi (Cortex Moutan) in Kidney Qi Pill%浅析肾气丸中牡丹皮的应用

    Institute of Scientific and Technical Information of China (English)

    杨梅; 陶汉华; 吕翠霞

    2016-01-01

    There are five cases treated with Kidney Qi Pill in Synopsis of Golden Chamber:dermatophytosis,consumptive disease,phlegm and fluid retention,consumptive thirst,impeded urination during late pregnancy.Despite of the many different symptoms,they share the common clinical manifestations of abnormal urination,or difficult urination,frequent and profuse urination.In the formula,Dihuang (Radix Rehmanniae) of 8 liang,Shangzhuyu (Fructus Corni) of 4 liang and Shanyao (Rhizoma Dioscoreae) of 4 liang are used to nourish kidney yin;Guizhi (Ramulus Cinnamomi) of 1 liang and Fuzi (Radix Aconiti Lateralis Praeparata) of 1 liang are used to warm and tonify kidney yang;Fuling (Poria) of 2 liang,Zexie (Rhizoma Alismatis) of 2 liang,Mudanpi (Cortex Moutan) of 2 liang are applied to promote diuresis and activate blood circulation.The pathogenesis of difficult or frequent and profuse urination lies in the deficiency and decline of kidney qi.Difficult urination is due to disorder of qi activity;frequent and profuse urination is due to the dysfunction of the kidney to consolidate;both of the above two are caused by deficiency of kidney qi,mainly due to the declined function in water metabolism dominated by the kidney.For the five diseases treated with Kidney Qi Pill,the one with unobvious symptom of deficient fire,the action of Mudanpi for "clearing and purging ministerial fire" lacks theoretical evidence;for the one with prominent disorder of water metabolism,Zhongjiang started the treatment from the academic idea of "disorder of the blood flow leads to water problem",and the effect of Mudanpi of activating blood and alleviate water retention is self-evident.%《金匮要略》一书中,用肾气丸者共有5处,分别为脚气、虚劳、痰饮、消渴、妇人转胞等,虽病证不一,但都有小便异常的症状表现,或小便不利,或尿频量多,方中重用干地黄为八两,山茱萸、山药各四两,滋补肾阴,配桂枝、附子各一两温补肾阳,又加茯苓、泽

  17. Research on conceptual framework of PRO scale in spleen Qi deficiency syndrome%脾气虚证PRO量表概念框架的探讨

    Institute of Scientific and Technical Information of China (English)

    林建东; 胡镜清; 刘保延

    2013-01-01

    [Objective] To develop a conceptual framework of patient-reported outcomes (PRO) scale in spleen Qi deficiency syndrome for the further development of scale items, the establishment of the item pool and lay a theoretical foundation. [Methods] The work was performed under the guidance of traditional Chinese medicine (TCM) theory and the direction of psychometrics. The formation of the conceptual framework of PRO scale in spleen Qi deficiency syndrome is set up according to the clinical features of spleen Qi deficiency syndrome, the production principles and processes of PRO scale in United States Food and Drug Administration (FDA) and combined with the WHO concept of health, TCM holistic concept and physiological functions of the spleen. [Results] The scale is composed of four domains: physiology domain, psychology domain, independence domain and social domain. The physiology domain is composed of three facets, which are symptoms of spleen deficiency, symptoms of Qi deficiency and symptoms of the five viscera. The psychology domain is composed of negative feelings and positive feelings. The independence domain is composed of three faces of the activities of daily living and work learning ability. The social domain is composed of social support and social relations. [Conclusion] The four domains and nine fields that formed by preliminary study of defmeing and explaining the conception of Spleen Qi Deficiency Syndrome generalize about the connotation and extension of it allsidely.%[目的]构建脾气虚证患者报告结局(PRO)量表的概念框架为进一步发展量表条目、建立条目池和量表的研制奠定理论基础.[方法]在中医传统理论的指导下,参照美国食品药品监督管理局(FDA)所规定的PRO量表的制作原则及流程,根据脾气虚证的临床特点,结合世界卫生组织(WHO)的健康概念、中医整体观念及脾脏的生理功能构建量表的概念框架.[结果]量表分为生理、心理、独立性和社会4

  18. 肝郁脾虚型疲劳性亚健康者疲劳状况、体质体能状态及两者相关性研究%Correlation between Fatigue and Basic Physical Fitness of Sub-health State of Fatigue Type and TCM Syndrome Pattern of Liver-qi Stagnation and Spleen-qi Deficiency

    Institute of Scientific and Technical Information of China (English)

    张雅静; 汤宇; 李真; 王文萍; 薛晓琳; 王天芳; 李冠儒; 王佳佳; 韩萍; 钟燕宇; 李力; 王庆波

    2011-01-01

    目的:探讨肝郁脾虚型疲劳性亚健康人群疲劳状况和体质体能间的相关性.方法:采用主观指标疲劳评定量表FSAS及客观指标GMCS-2型体质检测仪等,分别对符合纳入标准的200例肝郁脾虚型疲劳性亚健康人群的疲劳类型程度及特征、基本体质体能及认知功能(简单反应时)状况进行测评.结果:疲劳性亚健康肝郁脾虚型受试者的FSAS中躯体疲劳分别与体重、简单反应时呈显著正相关;精神疫劳、疲劳后果和疲劳程度总分分别与肺活量、台阶指数呈显著负相关;疲劳对睡眠休息的反应、疲劳的情境性分别与肺活量呈显著负相关;各因子均与简单反应时呈显著正相关.结论:疲劳性亚健康肝郁脾虚型人群的疲劳状况和体质体能间有较为显著的相关性.%Objective: To explore the correlation between the fatigue and the basic physical fitness in cases with sub-health of fatigue type and the TCM syndrome pattern of liver-qi stagnation and spleen-qi deficiency. Methods: 200 cases with sub-health of fatigue type and the TCM syndrome pattern of liver-qi stagnation and spleen-qi deficiency were chose from the three hospitals in Beijing, Henan and Liaoning,and their fatigue and the basic physical fitness and cognitive function were measured with Fatigue Selfassessment Scale ( FSAS ) and GMCS-2 type physical detector separately. Results: The factors of FSAS were positive correlation to height and weight and cognitive function; the mental fatigue, the consequences of fatigue and the fatigue scores were significantly negative correlation to vital capacity and the step test; the fatigue response after sleep / rest and the situations sensitive were significantly negative correlation to vital capacity; all factors were significantly positive correlation to cognitive function. Conclusion: The fatigue state in cases with sub-health of fatigue type and the TCM syndrome pattern of liver-qi stagnation and spleen-qi

  19. 行气活血法治疗2型糖尿病气滞血瘀证的临床研究%Clinical Study on Diabetes Type 2 of Qi Stagnation and Blood Stasis Treated with Promoting Flow of Qi and Blood Circulation Method

    Institute of Scientific and Technical Information of China (English)

    张国梁; 刘海英; 王珏; 姚燕珍; 赵志钧; 於松达; 於孝龙; 李亚平

    2009-01-01

    To observe the effects of promoting flow of qi and blood circulation method on platelet-activating factor, plasma endothelin and nitric oxide of patients with diabetes type 2 of qi stagnation and blood stasis.Meothods: 104 cases were divided into two groups, 53 cases was treatment group, 51 cases was control. Treatment group was given jiawei taohong siwu decoction, control was given taohong siwu decoction. The changes of clinical symptoms, blood viscosity,CD62p, CD63, PAC-1, ET and NO were observed and recorded.Results: To compare with before treated, the changes of clinical symptoms, blood viscosity,CD62p, CD63, PAC-1, ET and NO were improved after treated with jiawei taohong siwu decoction or taohong siwu decoction, there was obvious difference between treatment and control groups.Conclusion: The effects of promoting flow of qi and blood circulation method on diabetes type 2 of qi stagnation and blood stasis were veritable.%目的:观察行气活血法对2型糖尿病气滞血瘀证患者血小板活化因子及血浆内皮素、一氧化氮的影响.方法:104例患者,随机分为治疗组53例,对照组51例;治疗组服用加味桃红四物汤,对照组服用桃红四物汤;观察两组临床疗效、血黏度、CD62p、CD63、PAC-1和ET、NO的变化.结果:两组治疗前后组内比较,血黏度、CD62p、CD63、PAC-1和ET、NO的差异,治疗组有非常显著性意义(P<0.01),对照组有显著性意义(P<0.05);组间比较,差异有显著性意义(P<0.05).结论:行气活血法能降低2型糖尿病患者的血黏度,抑制血小板活化,调节内皮素和一氧化氮的分泌失衡,作用较活血化瘀法显著.

  20. [Effect of supplementing Qi-nourishing Yin-dispersing blood stasis-dredging collateral herbs on p38 MAPK signaling pathway in kidney of early diabetic rats].

    Science.gov (United States)

    Zhao, Wenhong; Chen, Zhiqiang; Zhang, Jianghua; Sun, Yufeng; Wang, Yuehua; Wang, Huiqing

    2010-03-01

    To study the effect of supplementing Qi-nourishing Yin and dispersing blood stasis-dredging collateral herbs on p38 mitogen activated protein kinase (p38 MAPK) signaling pathway in the kidney of early diabetic rats. Dividing SD rats randomly into 6 groups: Simple nephrectomy group, model group, irbesatan group, traditional Chinese medicine (TCM) low dose group, TCM middle dose group and TCM high dose group. Each group of rats was fed with the corresponding dose of medicine. After 6 weeks, detecting 24 h urine protein (UPro) level, renal function, p38 MAPK mRNA and p-p38 MAPK protein level. UPro levels of irbesatan group, TCM low group and TCM middle dose group decreased significantly (P herbs could treat DN rats effectively by inhibiting the expression of p38 MAPK signaling pathway.

  1. Effects of Replenishing Qi, Promoting Blood Circulation and Resolving Phlegm on Vascular Endothelial Function and Blood Coagulation System in Senile Patients with Hyperlipemia

    Institute of Scientific and Technical Information of China (English)

    Yang Huimin; Han Libei; Sheng Tong; He Qiong; Liang Jinpu

    2006-01-01

    Objective: To observe the curative effect of the method of replenishing qi, promoting blood circulation and resolving phlegm on senile hyperlipemia and its effects on vascular endothelial function and blood coagulation system. Method: 96 patients with senile hyperlipemia were randomly divided into a treatment group and a of blood lipid, vascular endothelial function, blood coagulation system and safety. Results: After treatment,the treatment group was obviously superior to the control group (P<0.05) in reducing plasma total cholesterol (TC) and low density lipoprotein cholesterol (LDL-C) as well as in the ratio of thromboxane B2 (TXB2) to 6-keto-prostaglandin F1α (6-keto-PGF1α), D-dimer (D-D) and fibrinogen (FIB). Conclusion: Danshen Jueming Granules have the effect of regulating metabolism of blood lipid, and improving vascular endothelial function and blood coagulation system in senile patients with hyperlipemia.

  2. Qualitative analysis of chemical constituents in traditional Chinese medicine analogous formula cheng-Qi decoctions by liquid chromatography-mass spectrometry.

    Science.gov (United States)

    Wen, Xuexun; Luo, Kedi; Xiao, Shun; Ai, Ni; Wang, Shufang; Fan, Xiaohui

    2016-03-01

    Cheng-Qi decoctions (CQs), a group of analogous formulas, are well-known traditional Chinese preparations used as purgative remedies to treat 'internal heat'-induced symptoms, which manifest as a bloated and painful abdomen, hard stools, fever and other clinical observations. In this study, HPLC-ESI-MS/MS and UPLC-TOF-MS were employed for separation and structural identification of constituents in CQs. As a result, a total of 90 compounds, including seven anthraquinones, 39 flavones, 21 glycosides, 11 stilbene glycosides, six organic acids, five coumarins and one lignans, were detected and tentatively identified in CQs extracts. The characterization results shed some light on the scientific foundation for clinical application of the CQ analogous formulas. Our results also indicate that the HPLC-MS method is useful for the systemic identification of major constituents in traditional Chinese medicine formulas. Copyright © 2015 John Wiley & Sons, Ltd.

  3. The Essence of Treatise on Spleen and Stomach Is the Theory of Fiver Circuits and Six qi%《脾胃论》的精髓是五运六气

    Institute of Scientific and Technical Information of China (English)

    田合禄

    2014-01-01

    本文认为,《脾胃论》的精髓是五运六气,该书是在“脏气法时”和“气运衰旺”指导下写成的,重视四时阴阳升降浮沉,把五运六气理论从外感引入到内伤之中,不但用五运六气理论阐述脾胃病的病因病机,还把五运六气理论扩大到治则及制方遣药方面去了。本文开发了研究脾胃内伤病的最新思路,值得重视。%This paper holds that the essence of Treatise on Spleen and Stomach is the theory of five circuits and six qi. The book is under the guidance of the theory that visceral qi is associated with four seasons and the circuit and qi rise and fall. It attaches importance on the ascending, descending, floating and sinking of four seasons and yin and yang. The book brings the the theory of five circuits and six qi from external contraction field to the internal damage area. It not only uses the theory of five circuits and six qi to explain the cause and pathogen of spleen and stomach diseases, but also expands the theory to the area of treatment principle and drugs and prescription application. This paper explore a newest idea for studying the internal damage diseases of spleen and stomach. It is worth attention.

  4. YiQiFuMai powder injection ameliorates blood–brain barrier dysfunction and brain edema after focal cerebral ischemia–reperfusion injury in mice

    Directory of Open Access Journals (Sweden)

    Cao GS

    2016-01-01

    Full Text Available Guosheng Cao, Xinyi Ye, Yingqiong Xu, Mingzhu Yin, Honglin Chen, Junping Kou, Boyang Yu Jiangsu Key Laboratory of TCM Evaluation and Translational Research, Department of Complex Prescription of TCM, China Pharmaceutical University, Nanjing, People’s Republic of China Abstract: YiQiFuMai powder injection (YQFM is a modern preparation derived from the traditional Chinese medicine Sheng-Mai-San. YQFM is widely used in clinical practice in the People’s Republic of China, mainly for the treatment of microcirculatory disturbance-related diseases. However, little is known about its role in animals with ischemic stroke. The aim of this study was to examine the effect of YQFM on brain edema and blood–brain barrier (BBB dysfunction induced by cerebral ischemia–reperfusion (I/R injury. Male C57BL/6J mice underwent right middle cerebral artery occlusion for 1 hour with a subsequent 24-hour reperfusion to produce I/R injury. YQFM (three doses: 0.336, 0.671, and 1.342 g/kg was then given intraperitoneally (IP. The results demonstrated that YQFM significantly decreased infarct size, improved neurological deficits, reduced brain water content, and increased cerebral blood flow after I/R injury. 18F-fluorodeoxyglucose micro-positron emission tomography imaging and hematoxylin and eosin staining results indicated that YQFM is able to ameliorate brain metabolism and histopathological damage after I/R. Moreover, YQFM administration reduced BBB leakage and upregulated the expression of zona occludens-1 (ZO-1 and occludin, which was confirmed by Evans Blue extravasation, Western blotting, and immunofluorescence assay. Our findings suggest that YQFM provides protection against focal cerebral I/R injury in mice, possibly by improving BBB dysfunction via upregulation of the expression of tight junction proteins. Keywords: YiQiFuMai powder injection, YQFM, ischemic stroke, blood–brain barrier, microvascular permeability, tight junctions

  5. Influence of LPS on the Temperature of Normal and Spleen-qi Deficiency Rat%LPS对正常和脾虚大鼠体温的影响

    Institute of Scientific and Technical Information of China (English)

    刘进娜; 谢鸣; 高秀兰; 赵荣华

    2011-01-01

    目的:比较LPS对不同状态大鼠体温的影响.方法:大鼠随机分为正常对照组、单纯发热组(正常+LPS)、脾虚发热组(脾虚+LPS)共3组,每组10只.脾虚发热组先用饮食失节+过度疲劳法复制脾虚模型,连续21天,每周末称量体重1次,并观察其外观行为表征变化.于造模第22天的上午8:00,脾虚发热组大鼠和单纯发热组大鼠腹腔注射LPS(80μg/kg),正常对照组注射等量生理盐水.分别于注射后30、60、120、180、240、330min测肛温,绘制各组平均体温曲线.结果:与正常对照组和单纯发热组比较,脾虚发热组大鼠在3周末的体重明显降低,差异有非常显著性意义(P<0.01).较之正常对照组和单纯发热组,脾虚发热组大鼠第3周出现动作迟缓、神情倦怠、饮食减少、毛发不泽、倦卧、便溏等变化,外观行为变化积分值明显升高,差异有非常显著性意义(P<0.01).与正常对照组比较,单纯发热组大鼠的体温在60、120、180、240、330min时均明显升高,脾虚发热组的体温在30min时有一过性降低,之后体温显著升高,其中在60、120、180、240min时的差异均具有非常显著或显著性意义(P<0.01或P<0.05);与单纯发热组相比,脾虚发热组大鼠体温在30、60、120、330min的体温降低,其差异均有显著或非常显著性意义(P<0.05或P<0.01).结论:LPS对正常和脾虚大鼠均可引起体温升高,但升高的体温在幅度和持续时间方面均有所不同.提示LPS引起机体发热的反应模式因机体状态而有所不同.%Objective:To compare the influence of LPS on the temperature of different state rat. Methods:The rats were assigned into the normal group, fever group, spleen-deficiency with fever group, 10 rats in every group. The rats of the spleen-qi deficiency with fever group were treated with excess fatigue plus out of constant diet to copy spleen-qi deficiency rat model. The body weight are measured and the change of

  6. Comparison of effect of granules and herbs of Bu-Shen-Yi-Qi-Tang on airway inflammation in asthmatic mice

    Institute of Scientific and Technical Information of China (English)

    Wei Ying; Lyu Yubao; Li Mihui; Luo Qingli; Sun Jing; Liu Feng; Lin Yanhua

    2014-01-01

    Background Bu-Shen-Yi-Qi-Tang (BSYQT),which is prescribed on the basis of clinical experience,is commonly used in clinics of traditional Chinese medicine (TCM) for asthma treatment.The components of BSYQT include Radix Astragali (RA),Herba Epimedii (HE) and Radix Rehmanniae (RR).The aim of this study was to compare the effect of granules and herbs of BSYQT on airway inflammation in asthmatic mice.Methods Sixty female BALB/c mice were randomly divided into the normal control (NC) group,asthmatic group (A),decoction of granules of BSYQT treatment group (GD),decoction of herbs of BSYQT treatment group (HD),and dexamethasone treatment group (DEX).The mouse asthmatic model was induced by ovalbumin (OVA) sensitization and challenge.GD and HD of BSYQT as well as DEX were prepared and administered by intragastric infusion.Airway hyperresponsiveness (AHR) to methacholine (Mch),lung histopathology analysis,inflammatory mediators in serum (IL-4,IL-5,IL-17A,IFN-γ,and eotaxin) and in lung (IL-4,IL-5,IFN-γ,and eotaxin) were selected for investigation and comparison.Results Both GD and HD treatment could decrease airway resistance (RL) and increase dynamic compliance (Cdyn) to Mch compared with the A group (P <0.05).HD treatment was more effective in RL reduction than Mch at doses of 3.125 and 6.25 mg/ml (P <0.05) and in Cdyn increase at Mch doses of 6.25 and 12.5 mg/ml (P <0.05).There were no marked differences in RL reduction and Cdyn improvement between mice in HD and DEX groups (P >0.05).Both GD and HD treatment markedly attenuated lung inflammation (P <0.05),and HD treatment demonstrated more significant therapeutic function in alleviating lung inflammation than that of GD and DEX treatment (P <0.05).Both GD and HD treatment resulted in a significant reduction in IL-4 and IL-17A levels and an increase in the IFN-γ level in serum compared with the A group (P <0.05).The effect of HD in lowering the IL-4 and IL-17A level was significantly greater than that of

  7. Yi-Qi-Zeng-Min-Tang,a Chinese medicine,ameliorates insulin resistance in type 2 diabetic rats

    Institute of Scientific and Technical Information of China (English)

    Zeng Zhang; Hong-Li Xue; Yi Liu; Wen-Jian Wang

    2011-01-01

    AIM:To investigate the effects of the Chinese herbal decoction,Yi-Qi-Zeng-Min-Tang (YQZMT),on insulin resistance in type 2 diabetic rats. METHODS:Sprague-Dawley rats were divided into two dietary regiments by feeding either normal pellet diet (NPD) or high fat diet (HFD).Four weeks later,the HFD-fed rats were injected intraperitoneally with lowdose streptozotocin (STZ).Rats with non-fasting blood glucose level ≥ 16.67 mmol/L were considered type 2 diabetic and further divided into five subgroups:the type 2 diabetes model group,low-dose,medium-dose and high-dose YQZMT groups,and rosiglitazone group. Age-matched NPD-fed rats served as controls.YQZMT or rosiglitazone were administered for 8 wk.Intraperitoneal glucose and insulin tolerance tests were performed before and after the treatment to measure the glucose tolerance and insulin sensitivity.Serum levels of biochemical parameters,adipocytokines,such as tumor necrosis factor-α (TNF-α),interleukin-6 (IL-6),as well as free fatty acids (FFAs),were also analyzed. RESULTS:There was significant elevation of insulin resistance and serum levels of fasting glucose (12.82 ± 1.08 mmol/L vs 3.60 ± 0.31 mmol/L,P < 0.01),insulin (7197.36 ± 253.89 pg/mL vs 4820.49 ± 326.89 pg/mL, P < 0.01),total cholesterol (TC) (8.40 ± 0.49 mmol/L vs 2.14 ± 0.06 mmol/L,P < 0.01),triglyceride (2.24 ± 0.12 mmol/L vs 0.78 ± 0.05 mmol/L,P < 0.01),low-density lipoprotein cholesterol (LDL-c) (7.84 ± 0.51 mmol/L vs 0.72 ± 0.04 mmol/L,P < 0.01) and decrease in high-density lipoprotein cholesterol (HDL-c) (0.57 ± 0.03 mmol/L vs 1.27 ± 0.03 mmol/L,P < 0.01) in the low-dose STZ and high-fat diet induced type 2 diabetic group when compared with the control group. Administration of YQZMT induced dose- and timedependent changes in insulin resistance,glucose and lipid profile,and reduced levels of FFA,TNF-α and IL-6 in the type 2 diabetic rats.After the treatment, compared with the diabetic group,the insulin resistance was ameliorated in the

  8. 画线测试在寒热气机量化的实验初探%Quantification Experiment of Drawing Lines to Analysis "the Qi Dynamic of Cold and Hot"

    Institute of Scientific and Technical Information of China (English)

    王米渠; 余小平; 刘红华; 张志芳; 王洪展; 范怀昌; 薛声波; 夏丽娜; 韩佩王; 张先庚

    2009-01-01

    Objeticive :To draw lines to analysis "the qi dynamic" ,finally ,find new methods and tools to evaluate it.Method:This experimental tests to quantify the use of painted lines on the observation the stimulation of "hot" and "cold "to "the qi dynamic" Using a variety of statistical methods to analysis of People draw lines of points and lines such as 12 Relevant factors by two - group evaluation staff. Quantitative analysis" hot" and "cold" stimulation on the effects of" the qi dynamic". Result: ①Draw a line before and after "hot" and "cold" stimulation test scores have significant differences,which can quantify the "the qi dynamic". ②Draw a line test with a certain degree of reliability and validity, the overall score were no significant differences in the factor with the line with the equivalent effect of assessment. ③In two different stimulations the points and lines have the equivalent effect of assessment. Conclusion : Draw a line test for evaluation of "the qi dynamic" has a certain degree of feasibility and bright prospects for the future. However,it adapted to the specific scope and quantitative method,which also need to be further explored. Diseussion:"The qi dynamic" is a fundamental question of traditonal chinese medicine, hot and cold stimulation to quantify the transmission of cold and heat will help drive changes of "the qi dynamic", which provides a theoretical basis, thereby drawing a line test to establish the methods to evaluate tradional Chinese medicine "qi". Development a new measurement tool of "the qi dynamic" ,it is not only has two potential advantages for catching up with the Rorschach inkblot test,but also opens up a promising new ideas for sci-entific research.%目的:建立一种以画线测试分析"气机"的新方法和新工具.方法:实验采用画线测试量化观察冷热刺激对中医学中"气机"的影响,运用多种统计学方法,采用两组测评人员对人们冷热刺激下前后画出的点以及线条的等12

  9. The Failure of Qi and the Birth of The Art of War--Perspective of the war between Qi and Jin in Zuozhuan%齐国的失败与《孙子兵法》的诞生——从《左传》所记齐、晋之战看《孙子兵法》的产生

    Institute of Scientific and Technical Information of China (English)

    吴名岗

    2011-01-01

    The failure in the war takes a profound and lasting impact on people of the defeated. Since the Battle of Qi Jin An in589 BC, the Battle of Pingyin in 555 BC, being afraid of the invasion of Jin and the Murder of Qi Zhuanggong by CUI Zhu in 548 BC,Qi suffered three successive defeats. Sun Tzu as the offspring of a general had a deeper and painful feeling for this series of failure and humiliation. "It is only one who is thoroughly acquainted with the evils of war that can thoroughly understand the profitable way of carrying it on. " The Art of War is not only full of the wisdom of the people of Qi,but full of pains and lessons from failure. To know the effect of Qi's history of failure on the creation of The Art of War is vital to understand The Art of War correctly and be referential to make decisions facing war Qi failed to understand the history of this creation of Sun Tzu TheArt of War effect,not only for us to correctly understand The Art of War is important,but the reality of our war in the face of choice, there is still an important reference.%战争失败对战败国人民的影响是深远而持久的。自公元前589年的齐晋鞌之战,前555年的齐晋平阴之战,前550年的齐庄公伐晋,到前548年的害怕晋国入侵,齐卿崔杼弑齐庄公,齐国接连遭受三次惨败。身为将门之后的孙武,对这一系列失败和屈辱的感受比常人更深刻,更痛苦。“不尽知用兵之害者,则不能尽知用兵之利也。”《孙子兵法》不仅充满了齐国人民的智慧,也饱含了齐国惨败的痛苦和教训。了解齐国这段失败的历史对孙武创作《孙子兵法》的影响,不仅对正确理解《孙子兵法》是重要的,而且对我们在面对现实的战争选择时,仍有重要的借鉴意义。

  10. Effects of Qi Deficiency and Blood Stasis Syndrome after Percutaneous Coronary Intervention on Antithrombotic Therapy%冠脉介入术后气虚血瘀证对抗栓疗效的影响

    Institute of Scientific and Technical Information of China (English)

    张娅; 陈慧; 李灿东; 吴红霞; 林云钗

    2011-01-01

    Objective: To analyze the effects of qi deficiency and blood stasis syndrome after Percutaneous Coronary Interven tion PCI) on antithrombotic therapy. Methods; We adopted 123 CHD patients after receiving successful PCI. After 7 days of stand ard antithrombotic therapy, Traditional Chinese Medicine (TCM) syndromes were differentiated into qi - deficiency blood - stasis type and non - qi - deficiency blood - stasis type. All patients were detected platelet count ( PLT) , maximum platelet aggregation rate( MPA) , plasma von Willebrand factor(vWF) >platelet membrane glycoproteins II b/II! A ( GP II b/IE a) , prothrombin frag mentl + 2 ( Fl + 2 ) and fibrinogen ( Fg ) . Results; Compared with the non - qi - deficiency blood - stasis group after PCI, the MPA ^ vWF and GP II b/ IH a were obviously higher in qi - deficiency blood - stasis group (P 0.05). Conclusion:Qi deficiency and blood stasis syndrome after PCI affected platelete activation and ndothelial function on standard antithrombotic therapy,whereas the number of blood platelet and coagulation function were not.%目的:探讨经皮冠状动脉介入(PCI)术后气虚血瘀证对抗栓疗效的影响.方法:123例行PCI成功的冠心痛患者进行术后规范抗栓治疗,根据术后1周是否有气虚血瘀证表型分为气虚血瘀组(49例)和非气虚血瘀组(74例),同时采血检测血小板计数(PLT)、最大血小板聚集率(MPA)、血浆遗传性假血友病因子(vWF)、血小板膜糖蛋白Ⅱb/Ⅲa( GPⅡb/Ⅲa)、凝血酶原片段1+2(F1 +2)和纤维蛋白原(Fg).结果:PCI术后气虚血瘀组MPA、vWF、GPⅡb/Ⅲa高于非气虚血瘀组(P<0.05),而PLT、F(1+2)和Fg两组间差异无统计学意义(P>0.05).结论:在PCI术后强化抗栓治疗的基础上,气虚血瘀证仍然存在明显的血小板活化和血管内皮损伤,但不影响血小板数量和凝血功能.

  11. 肝衰竭患者胃气定量评估及其与预后的关系%Gastric qi quantitative assessment and its influence on prognosis in liver failure patients

    Institute of Scientific and Technical Information of China (English)

    茹清静; 叶卫江; 杨丹红; 郑临; 崔景; 章亮; 施维群; 徐珊

    2012-01-01

    Objective: Establishing a quantitative evaluation model of gastric qi damage, examining the reliability and validity of the model, exploring the relativity between gastric qi damage and prognosis in liver failure patients. Methods; ① Studying 136 cases of liver failure with a prospective multicenter cases queue follow-up study. While observing the indexes including gastric qi injurydamage scores, indexes of serum biochemistry, MELD scores and living condition for 1, 3, 6 months from admission. ②The damaged degree of gastric qi is graded according to the 8 indexes including 'degree of the appetite fails' , 'degree of abdominal distension' , 'adverse rising of gastric qi degrees' , 'degree of diarrhoea' . 'degree of weakness ' , 'inspection of spirit, color and skin' , 'nutritional status' , 'observation of tongue fur' , and analysised the reliability; To work out the judgment model of prognosis of liver failure with TCM characteristics, and compare it with MELD model. Results: ①The ' gastric qi' scale has the sablility and concordance. ②The scores of gastric qi damages are positive correlated with the scores of MELD. R=0.323, p<0.01. At the same time, there is remarkable difference of the scores of gastric qi damages and MELD scores between the death group and survive group. ③The area under curve(AUC) of gastric qi model is 0.663, P=0.001. When the score of gastric qi damage is 11, it predicts the sensitivity of the death risk is 62%, the specificity is 60%. Conclusion: The scale of gastric qi injury on liver failure patients is simple and practica, and has stability and consistency by inherent reliability analysis. The score of gastric qi damages has positive correlation with MELD scores; The gastric qi injury score and TCM predictive model could predict the death risk of of liver failure patients in the near future.%目的:建立胃气损伤的量化评分表,进行信度和效度的检验;探讨肝衰竭患者胃气损伤与预后的关系.方法:①

  12. Effect of Chinese Drugs for Supplementing Qi, Nourishing Yin and Activating Blood Circulation on Myocardial Perfusion in Patients with Acute Myocardial Infarction after Revascularization

    Institute of Scientific and Technical Information of China (English)

    LI Yong-qiang; JIN Mei; QIU Sheng-lei; WANG Pei-li; ZHU Tian-gang; WANG Cheng-long; LI Tian-chang; LIU Hong-xu; BIAN Hong; YAO Li-fang; SHI Da-zhuo

    2009-01-01

    Objective: To observe the effects of Chinese drugs for supplementing qi, nourishing yin and activating blood circulation on the myocardial perfusion in acute myocardial infarction (AMI) patients after revascularization. Methods: Eighty patients with anterior or inferior ventricular wall AMI, who had received revascularization by intravenous thrombolysis or coronary bypass, were randomized into the treated group and the control group equally, both treated with conventional Western medical treatment, but combined, respectively, Dobutamine stress echocardiography (DSE) was performed 14 days and 3 months after revascularization, respectively on every patient to observe blood perfusion extent (b value), myocardial perfusion velocity (k value) and local blood flow volume (k × b) in left ventricular infarction-related vascular segments under stressed state. Results: With 5 cases dropping out in the observation pedod (3 in the treated group and 2 in the control group), the tdal was completed in 75 patients in total. The 14-day DSE shows that the b value and k×b value of left anterior ventricular wall mid segment and apex segment, and the k value of apex segment in patients with antedor wall AMI, as well as the b value and k×b of basel segment in patients with infedor wall AMI in the treated group were significantly higher than those in the control group (P<0.05 or P<0.01). The 3-month DSE shows that the b value of apex segment, k×b value of basal segment, mid segment and apex segment of left anterior ventdcular wall in patients with anterior wall AMI as well as the b value and k x b value of basal segment of left infedor ventricular wall in patients with inferior wall AMI were all higher in the treated group than those in the control group, respectively (P<0.05). The comparison between 14-day DSE and 3-month DSE in the treated group showed that the b value of apex segment of left antedor ventdcular wall in patients with antedor wall AMI and the k×b value of apex

  13. Measurements of VOC fluxes by Eddy-covariance with a PTR-Qi-TOF-MS over a mature wheat crop near Paris: Evaluation of data quality and uncertainties.

    Science.gov (United States)

    Buysse, Pauline; Loubet, Benjamin; Ciuraru, Raluca; Lafouge, Florence; Zurfluh, Olivier; Gonzaga-Gomez, Lais; Fanucci, Olivier; Gueudet, Jean-Christophe; Decuq, Céline; Gros, Valérie; Sarda, Roland; Zannoni, Nora

    2017-04-01

    The quantification of volatile organic compounds (VOC) fluxes exchanged by terrestrial ecosystems is of large interest because of their influence on the chemistry and composition of the atmosphere including aerosols and oxidants. Latest developments in the techniques for detecting, identifying and measuring VOC fluxes have considerably improved the abilities to get reliable estimates. Among these, the eddy-covariance (EC) methodology constitutes the most direct approach, and relies on both well-established principles (Aubinet et al. 2000) and a sound continuously worldwide improving experience. The combination of the EC methodology with the latest proton-transfer-reaction mass spectrometer (PTR-MS) device, the PTR-Qi-TOF-MS, which allows the identification and quantification of more than 500 VOC at high frequency, now provides a very powerful and precise tool for an accurate quantification of VOC fluxes on various types of terrestrial ecosystems. The complexity of the whole methodology however demands that several data quality requirements are fulfilled. VOC fluxes were measured by EC with a PTR-Qi-TOF-MS (national instrument within the ANAEE-France framework) for one month and a half over a mature wheat crop near Paris (FR-GRI ICOS site). Most important emissions (by descending order) were observed from detected compounds with mass-over-charge (m/z) ratios of 33.033 (methanol), 45.033 (acetaldehyde), 93.033 (not identified yet), 59.049 (acetone), and 63.026 (dimethyl sulfide or DMS). Emissions from higher-mass compounds, which might be due to pesticide applications at the beginning of our observation period, were also detected. Some compounds were also seen to deposit (e.g. m/z 47.013, 71.085, 75.044, 83.05) while others exhibited bidirectional fluxes (e.g. m/z 57.07, 69.07). Before analyzing VOC flux responses to meteorological and crop development drivers, a data quality check was performed which included (i) uncertainty analysis of mass and concentration

  14. Effect of Qi- benefiting, Qi -promoting and Blood- activating Therapies on CoronaryHeart Disease with Blood -stasis Syndrome%益气、行气活血法在冠心病心血瘀阻证中的治疗作用研究

    Institute of Scientific and Technical Information of China (English)

    冼绍祥; 黄鹂; 刘小虹; 刘亦选

    2001-01-01

    Objective: To study the therapeutic mechanism of qi-promoting with blood activating(QP-BA)therapies for coronary heart disease with blood - stasis syndrome, and provide the evidence for clinical syndrome differentiation and treatment. Methods: 30 cases with qi- stagnation and blood- stasis and 30 cases with qi- deficiency and blood- stasis were randomly treated by QPBA and QB - BA therapies, and the symptoms, signs, platelet agglutination rate, blood rheology and atrial natriuretic factor were observed before and after treatment. Results: Both therapies can alleviate the hyperfunction of platelets and the concentration, viscocity, coagulation and aggregation of blood, but the QB - BA therapy can also enhance the cardiac function and reduce the pressure and dilatation of atrium. The best effect is obtained when the treatment is in accordance with the syndrome differentiation. Conclusion: Treatment according to differentiation may get the greatest efficacy.%目的:探讨行气活血法和益气活血法对冠心病心血瘀阻证的治疗原理,为临床辨证用药提供依据。方法:从冠心病患者中随机抽取气滞心血瘀阻证30例和气虚心血瘀阻证30例,再将它们随机分配到行气活血法组和益气活血法组中治疗,检测治疗前后的症状、体征、血小板聚集率、血液流变学及心钠素的变化。结果:行气活血法和益气活血法都可以改善患者血小板功能亢进、血液的浓、粘、凝、聚状态,而益气活血法还可增强心功能、减轻心房的压力和扩张程度,而且发现2种治法对证治疗时,效果最佳。结论:辨证论治能发挥治疗的最大效应。

  15. Discuss on the Implication of Dispersing Lung Qi to Deal with Depression%试述宣肺开郁法指导治疗抑郁症的意义

    Institute of Scientific and Technical Information of China (English)

    傅丽

    2011-01-01

    The therapy of depression comes in for a great deal of attention.Doctors of Traditional Chinese Medicine are also in search of the pathogenesis and occurrence of the disease.The method of dispersing lung qi may be taken as a guide in treating depression which is mainly caused by the disorder of qi-movement.The theoretical and clinical relations of lung and liver in treating depression ( Yu-syndrome )is summarized.%抑郁症的治疗越来越受重视,中医也在探索并总结其病因病机及证型.以宣肺开郁为指导思想,初步探讨其对治疗由气机失调引起的抑郁症的指导意义,总结肺、肝与郁证理论联系及临床运用关系.

  16. Metallogenetic Prediction Based on an Ore-Prospecting Model:An Application of QI Ⅰ Gold Deposit Prospecting Model%基于找矿模型的成矿预测——以齐Ⅰ金矿为例

    Institute of Scientific and Technical Information of China (English)

    曾祥武; 刘家军; 赖月荣; 刘雪刚

    2012-01-01

    安齐成矿带是新疆重要金成矿带,齐Ⅰ金矿是该成矿带目前发现的最大金矿床.对比齐Ⅰ金矿找矿模型,结合遥感解译成果,在周边地区应用地质、物探、化探、遥感等找矿方法进行成矿预测,圈定出多处找矿靶区,经工程验证,发现工业矿体.利用找矿模型以现有资料为基础,以有效勘查方法组合为手段,设计验证工程,指导找矿勘探工作.%The QI I gold deposit is the biggest gold deposit metallogenic belt in anqi,one of the most important gold deposits in XinJiang.In order to enhance geological research and summarize the results of previous survey to guide the later prospecting work,we make comparison with the QI I gold prospecting model and use the remote sensing information to analyze the conditions of mineral formation in this area. Based on QI I ore-prospecting model,we successfully applied a set of effective working methods which integrate geology,geophysics,geochemistry and remote sensing to locate the target ore area quickly around QI I gold deposit. Located some target ore areas,with Au,Ag,As anomaly.Anomaly inspection led to the discovery of the new ore-body,which shows that target selection was fairly successful.On the basis of the prospecting model and comprehensive analysis of the resource potentials scientific resource prospecting plan is put forward and performed,with the ore body in depth being the main exploratory target.

  17. "Qi-Huang" Culture in the context of anthropological perspective of medicine and health%医药卫生人类学视野语境中的"岐黄"文化

    Institute of Scientific and Technical Information of China (English)

    郑怀林

    2011-01-01

    The survey of the two Chinese characters "岐(qi)黄(huang)" from the perspective of anthropology of medicine and health show that the words represent a variety of meanings. All the TCM related contents, such as physicians, medical works and official position of medicine etc. can be represented by the word. " Qi - huang" culture contained the relevant medical works and the physicians who handed down Chinese medicine, such as Qibo, Bogao, Shaoshi, Leigong, Rongcheng etc. , and the contents are more abundant. Previously, less study concerned the historical relics spread extensively in Xinmi City, Henan Province, such as Qibo Shan, Limu Tai, Fenghou Ding etc. " Qi - huang" culture not only remained in the history, but also are living vividly in the present medical civilization. " Qi - huang" culture is not confined within China, but has been spread to the whole world.%从医药卫生人类学的视角加以审视,可以发现"岐黄"二字代表了多种含义,"岐黄"文化所包含的内容,既有相关医籍,又有中医学传承早期的医家,如岐伯、伯高、少师、雷公、容成等.在以往的研究中,少被人关注的是遍布河南省新密市的各种遗迹,如岐伯山、力牧台、风后顶等."岐黄"文化不仅仅存留在历史中,更体现在当下的活态医药文明中."岐黄"文化也不局限于中国,而是已经传遍了四海五洲.

  18. 煤焦油喹啉不溶物压滤脱除和超净沥青制备%Pressure Filtration Removal of QI and Preparation of Ultra-clean Pitch from Coal Tar

    Institute of Scientific and Technical Information of China (English)

    王芳杰; 王永刚; 任浩华; 马伟光; 陈航; 郭相坤; 许德平

    2011-01-01

    以高温煤焦油为原料,在自制小型压滤装置上脱除喹啉不溶物(QI),并对滤后煤焦油进行超临界流体萃取分馏制备超净沥青.结果表明,当滤布孔径1250目、温度125℃、压力0.5MPa时,煤焦油中的QI质量分数可降低到0.037%.对压滤后的焦油进行超临界萃取,所制沥青的QI和甲苯不溶物质量分数分别达到0.10%和20.31%,可满足制备高性能炭素材料前驱体的要求.%Quinoline insolubles (QI) of high temperature coal tar sampled from a coking plant of Shanxi province was removed by a self-made pressure filtration device. Ultra-clean pitch was prepared from the filtered coal tar by utilizing supercritical fluid extraction and fractionation (SFEF). Results indicated that the QI content of the filtered coal tar decreased to 0.037% at the conditions of 1 250 mesh filter cloth, 125℃ and 0.5MPa. And the QI and toluene insoluble (TI) level of ultra-clean pitch from SFEF reached 0.1% and 20.31%, which indicated that the pitch could be used as a premium precursor for high-performance carbon material, especially the needle-coke.

  19. On Xie Zhangting's "Ci-qi" Theory%词气理论的成熟形态——谢章铤"词气说"的独特内涵

    Institute of Scientific and Technical Information of China (English)

    袁志成; 唐朝晖

    2009-01-01

    "气"是中国传统诗学重要的理论范畴,在构建诗学体系中有其不容忽视的地位和作用.在词学领域,谢章铤在其"性情说"的基础上,发展前人有关词气的理论成果,形成较为完整的"词气说",将词气理论形态推向成熟.其"词气说"有着独特的内涵,包括和永与豪雅的词人之气、词作内容之气以及和而不促的词作行文之气."词气说"与责气、气厚、词量等相关的词学命题联系起来,丰富并拓展了近代词学理论的范畴.%"Qi" is the traditional Chinese Poetics important theoretical areas,while building Poetics system has its important position and role.In the field of"Ci",Xie Zhangting made useful exploration in the"Ci-qi",on the basis of inheriting,developed their predecessors the"Ci gas" theoretical results,and formed relatively complete"Ci-qi"theory, including calm and long and hoya people of gas and the content of the text, and the calm and not hasty language of text,and"Ci-qi" associated with the proposition as Mack,thick air, linked to the volume of the word,enriched and expanded the"Ci"theory in the modern history.

  20. A ginástica terapêutica e preventiva chinesa Lian Gong/Qi Gong como um dos instrumentos na prevenção e reabilitação da LER/DORT

    Directory of Open Access Journals (Sweden)

    Gutembergue Livramento

    Full Text Available Este ensaio traz elementos da medicina ocidental, da medicina tradicional chinesa e da sociologia do trabalho para reflexão sobre o Qi Gong - exercícios terapêuticos, um dos pilares da Medicina Tradicional Chinesa (MTC - como importante meio de prevenção da LER/DORT e recuperação da saúde. Considerando a natureza interdisciplinar e diversos níveis de prevenção, aborda aspectos sociológicos sobre as condições de trabalho frequentemente relacionadas com este tipo de adoecimento e categorias de trabalhadores mais acometidos. Focaliza aspectos médicos sobre a LER/DORT e as Síndromes de Bloqueio na MTC, estabelecendo canais de articulação e contribuição entre esses campos de conhecimento sobre a saúde humana. Ressalta o Qi Gong como importante prática terapêutica e preventiva na MTC e sua adequação à LER/DORT. No âmbito do Qi Gong, focaliza o Lian Gong Shi Ba Fa - Lian Gong em 18 Terapias, já amplamente experimentado na China e divulgado, inclusive no Brasil, para tratar e prevenir síndromes de dor em região cervical, ombros, membros superiores, membros inferiores e região lombar. À guisa de conclusão, são apresentadas algumas reflexões sobre a propriedade e a importância do Qi Gong na reabilitação e na prevenção da LER/DORT.

  1. Survey of Mirrorcasting Workshop-sites of the Han Period in the Qi Princedom Capital Linzi within Shandong%山东临淄齐国故城内汉代铸镜作坊址的调查

    Institute of Scientific and Technical Information of China (English)

    中国社会科学院考古研究所; 山东省文物考古研究所

    2004-01-01

    The ancient city Linzi in Shandong Province was the capital of the Qi State in the Zhou Dynasty, the seat of the Qi and Linzi prefectures in the Qin-Han period, and the capital of the Qi Princedom of the Han Dynasty. In the spring of 2003, a special archaeological survey was carried out to explore mirror-casting workshops of the Han period in the city. The work resulted in the collection of 14 mirror-casting pottery molds and some related objects from the southeast of Shifotang Village and the west of Sujiamiao Village, thus the two localities can be determined to have been Han period mirror-casting workshops. Among the molds are those with herd design or connected arcs pattern, which are the first archaeological finds of this type and have high value to the study into the mirror-casting technology of the Han period. The discovery shows that the city of Linzi in the Han Dynasty was an important mirror-casting center, and that mirror casting was a part of the technology of multifunction foundries.

  2. 益气活血汤对癌症患者生存质量的影响%The impact of decoction for supplementing qi and activating blood circulation on quality of life of cancer patients

    Institute of Scientific and Technical Information of China (English)

    黄智芬; 施智严; 刘祥珍

    2002-01-01

    Objective To investigate effect of decoction for supplementing qi and activating blood circulation on quality of life of cancer patients.Method 64 patients were randomly divided into study group (n=35)and control group(n=29),study group received decoction for supplementing qi and activating blood circulation and control group received strong white cells enhancing tablets.Result Total effective rate for study group and control group was 82.8% and 65.5% ,respectively.For study group,quality of life was improved by 45.7% ,survival rate for 1 year was 88.6% ,median survical period was 16.5 months.For control group, quality of life was improved by 31% ,survival rate for 1 year was 58.6% ,median survival period was 9.6 months.Conclusion Decoction for supplementing qi and activating blood circulation markedly improve immune function,lighten adverse and toxicological reactions,and hence improveing patients quality of life.

  3. Effects of food and gender on the pharmacokinetics of rhein and emodin in rats after oral dosing with Da-Cheng-Qi decoction.

    Science.gov (United States)

    Gong, HanLin; Tang, WenFu; Wang, Hong; Xia, Qing; Huang, Xi

    2011-01-01

    Da-Cheng-Qi decoction (DCQD), a traditional Chinese medicine preparation used to treat digestive diseases, is composed of dahuang (Rheum officinale Baill, Polygonaceae), houpu (Magnolia officinalis Rehd., Magnoliaceae), zhishi (Citrus aurantium L, Rutaceae) and mangxiao (sodium sulphate). Rhein and emodin are the major active components of Rheum officinale Baill. To investigate the effects of food and gender on the plasma concentrations of rhein and emodin after oral administration of DCQD, a rapid high-performance liquid chromatographic method was developed and validated. A reversed phase C(18) column (150 × 4.6 mm) and a mobile phase of methanol and 0.2% acetic acid (78:22, v/v) were employed with ultraviolet detection at 254 nm. Feeding was observed to decrease the absorption of rhein and emodin in rats receiving DCQD orally. No evidence for gender-based differences in the pharmacokinetics of rhein was observed. However, the half-life and area under the concentration-time curve for emodin differed significantly between male and female rats. Because food intake and gender are anticipated to influence the pharmacokinetics of DCQD in human subjects, it is recommended that oral doses of DCQD be reduced in fasting subjects and that female patients receive lower oral doses compared with male patients.

  4. Treatment experience of ZHENG Qi-zhong in pertussis from the liver%郑启仲教授从肝论治百日咳经验

    Institute of Scientific and Technical Information of China (English)

    郑宏; 郑攀

    2011-01-01

    郑启仲教授从事中医儿科临床40余年,对百日咳的治疗有丰富的经验.文章从病因病机、临床见证、治疗经验等方面,结合典型病案,从肝论治百日咳,郑教授提出"木火刑金,风痰相搏"的病机特点,创拟镇肝止咳汤,取得了良好的疗效.%Professor ZHENG Qi-zhong, the nation's third and fourth batches inherit the old Chinese medicine experts,the work of academic experience instructors, and doctoral supervisor, worked 40 years in pediatric clinical medicine, who was expert in the treatment of whooping cough. In this paper, we discussed the treatment of whooping cough from the live on the basis of pathogenesis, clinical testimony, and treatment experiences with typical medical record, and proposed, the characteristics of the pathogenesis that 'wooden stake gold, wind phlegm Competing', and created Zhengan Zhike Tang, which obtained good effect.

  5. 七等生小说的自我认同与自我超越%Self -recognition and Self -transcendence of QI Deng-sheng’s Novels

    Institute of Scientific and Technical Information of China (English)

    刘翔

    2015-01-01

    QI Deng -sheng’s Novels express his personal psychological experiences and the reflection of his philosophy .In his novels ,he examines his own inner world sincerely ,and shows the social unrea‐sonable distortion of human nature and his terrible living conditions .Through his works ,he seeks to find a way to get out of his own trouble ,showing the same trouble for many modern people ,which is exactly the common emotion and demand of mankind and also the fascinating places in his works .%七等生的小说是他个人的心理经历与哲学思索的体现。在他的小说中他真诚地审视自我的内心世界,透过小说的形式表现出社会对人性种种不合理的扭曲及个人所遭遇到的生存困境。他通过作品为个人的生存困境寻求出口,也呈现出现代人所共同遭遇的困境。这正是人类所共通的情感及需求,也是七等生的作品中令人着迷之处。

  6. Qi Biaojia’ s Home Life Recorded inRenwu Calendar%从《壬午日历》看祁彪佳的家居生活

    Institute of Scientific and Technical Information of China (English)

    李庆勇

    2016-01-01

    Renwu Calendar records Qi Biaojia’ s course of life in 1642. The diaries of the first ten months record his life at home which mainly covers his contact with friends, production and operation, disaster and poverty relief, construction of his residence, reading and writing of books. His life at home has distinctive features, reflecting both his own life and social landscapes of his time.%《壬午日历》记载了祁彪佳在1642年的生活轨迹,其中前十个月的日记记载了他在家时的生活情况,通过日记可以看出他的家居生活主要有五项:交友往来;生产经营;赈灾济穷;建造寓园;读书辑书。其家居生活有着鲜明的特点,既反映出个人的生活情况,又折射出当时的社会风貌。

  7. YiQiFuMai powder injection ameliorates blood-brain barrier dysfunction and brain edema after focal cerebral ischemia-reperfusion injury in mice.

    Science.gov (United States)

    Cao, Guosheng; Ye, Xinyi; Xu, Yingqiong; Yin, Mingzhu; Chen, Honglin; Kou, Junping; Yu, Boyang

    2016-01-01

    YiQiFuMai powder injection (YQFM) is a modern preparation derived from the traditional Chinese medicine Sheng-Mai-San. YQFM is widely used in clinical practice in the People's Republic of China, mainly for the treatment of microcirculatory disturbance-related diseases. However, little is known about its role in animals with ischemic stroke. The aim of this study was to examine the effect of YQFM on brain edema and blood-brain barrier (BBB) dysfunction induced by cerebral ischemia-reperfusion (I/R) injury. Male C57BL/6J mice underwent right middle cerebral artery occlusion for 1 hour with a subsequent 24-hour reperfusion to produce I/R injury. YQFM (three doses: 0.336, 0.671, and 1.342 g/kg) was then given intraperitoneally (IP). The results demonstrated that YQFM significantly decreased infarct size, improved neurological deficits, reduced brain water content, and increased cerebral blood flow after I/R injury. 18F-fluorodeoxyglucose micro-positron emission tomography imaging and hematoxylin and eosin staining results indicated that YQFM is able to ameliorate brain metabolism and histopathological damage after I/R. Moreover, YQFM administration reduced BBB leakage and upregulated the expression of zona occludens-1 (ZO-1) and occludin, which was confirmed by Evans Blue extravasation, Western blotting, and immunofluorescence assay. Our findings suggest that YQFM provides protection against focal cerebral I/R injury in mice, possibly by improving BBB dysfunction via upregulation of the expression of tight junction proteins.

  8. Metabonomic phenotype and identification of "heart blood stasis obstruction pattern" and "qi and yin deficiency pattern" of myocardial ischemia rat models

    Institute of Scientific and Technical Information of China (English)

    YAN Bei; GU ShengHua; HUANG Qing; ZHENG YuanTing; A JiYe; HAO HaiPing; WANG GuangJi; ZHU XuanXuan; ZHA WeiBin; LIU LinSheng; GUAN EnZe; ZHANG Ying

    2009-01-01

    The traditional Chinese medicine concepts of "Xinxueyuzuzheng (heart blood stasis obstruction pattern)" and "Qiyinliangxuzheng (qi and yin deficiency pattern)" for myocardial ischemia rat models were constructed in the present study.Endogenous metabolites in rat plasma were analyzed using the GC/TOF-MS-based metabonomic method.Significant metabolic differences were observed between the control and two model groups,and the three groups were distinguished clearly by pattern recognition.Compared with those of the control,the levels of hydroxyproline,threonic acid,glutamine and citric acid were strikingly up-or down-regulated in model rats.The metabolites contributing most to the classification between the two "pattern" rats were identified,such as valine,serine,threonine,ornithine,hydroxyproline,lysine,2-hydroxybutanoic acid,3.hydroxybutanoic acid,galactofuranose and inositol.These compounds were indicated as the potential biomarkers.The results suggested that the two "patterns" are involved in dysfunction in oxidative stress,energy metabolism and amino acid metabolism.These findings also provided the substantial foundation for exploring the scientific connotation of these two "Zhengxing (pattern types)" of myocardial ischemia,and "Bianzheng (pattern identification)".

  9. Metabonomic phenotype and identification of “heart blood stasis obstruction pattern” and “qi and yin deficiency pattern” of myocardial ischemia rat models

    Institute of Scientific and Technical Information of China (English)

    2009-01-01

    The traditional Chinese medicine concepts of "Xinxueyuzuzheng (heart blood stasis obstruction pattern)" and "Qiyinliangxuzheng (qi and yin deficiency pattern)" for myocardial ischemia rat models were constructed in the present study. Endogenous metabolites in rat plasma were analyzed using the GC/TOF-MS-based metabonomic method. Significant metabolic differences were observed between the control and two model groups, and the three groups were distinguished clearly by pattern recognition. Compared with those of the control, the levels of hydroxyproline, threonic acid, glutamine and citric acid were strikingly up or down-regulated in model rats. The metabolites contributing most to the classification between the two "pattern" rats were identified, such as valine, serine, threonine, ornithine, hydroxyproline, lysine, 2-hydroxybutanoic acid, 3-hydroxybutanoic acid, galactofuranose and inositol. These compounds were indicated as the potential biomarkers. The results suggested that the two "patterns" are involved in dysfunction in oxidative stress, energy metabolism and amino acid metabolism. These findings also provided the substantial foundation for exploring the scientific connotation of these two "Zhengxing (pattern types)" of myocardial ischemia, and "Bianzheng (pattern identification)".

  10. 辛弃疾信州山水词初探%A Study of XIN Qi-j i's Landscape-Ci of Xinzhou

    Institute of Scientific and Technical Information of China (English)

    陈晓芸; 刘宇龙

    2016-01-01

    XIN Qi-ji, during his twenty years'stay in Xinzhou, often traveled and enjoyed the beauty of landscape, therefore leaving a lot of masterpieces of chant.According to the statistics, among his Landscape-Ci, there are about 60 Ci-writings about Xinzhou's landscape, in which there are about 40 beauty spots recorded.All these beauty spots were not far from his dwelling place, and XIN himself visited them all and had a lot of perception, so his writings of the landscape are always endowed with his own sense of life experience.%辛弃疾侨寓信州20余年,他时常游历观赏山水之美景,留下许多咏叹的佳作。据统计,辛弃疾山水词中,全词围绕古信州山水风景点叙写的作品有60余首,所记游历的风景大约有40余处。这些景点距离其寓所大都不远,词中所选择的景点都是词人亲身游历过且自身对之颇有感悟的景点,对这些山水风光的叙写,往往寄寓了作者的身世之感。

  11. Bu-Zhong-Yi-Qi Decoction, the Water Extract of Chinese Traditional Herbal Medicine, Enhances Cisplatin Cytotoxicity in A549/DDP Cells through Induction of Apoptosis and Autophagy

    Science.gov (United States)

    Xiong, Ying

    2017-01-01

    Cisplatin is one of the most active cytotoxic agents for non-small cell lung cancer (NSCLC) treatment. However, the development of cisplatin resistance is common. Bu-Zhong-Yi-Qi decoction (BZYQD), a Chinese traditional herbal medicine, is widely used for the enhancement of antitumor effect in other medications. In this study, we evaluated the effect and drug-resistance reversal mechanism of BZYQD combined with cisplatin on cisplatin-resistant A549/DDP cells. Our results showed that BZYQD exhibited direct cytotoxic and chemosensitizing effects. Cotreatment with BZYQD and cisplatin induced intrinsic apoptotic pathways which were measured by condensed nuclear chromatin, Annexin V/PI apoptosis assay, and apoptosis related proteins expression. In addition, cotreatment with BZYQD and cisplatin also activated autophagy, as indicated by an increase in LC3 puncta, classical autophagosomes and/or autolysosomes, and an accumulation of LC3-II and ATG7 protein. Finally, cotreatment with BZYQD and cisplatin resulted in the generation of ROS and scavenging ROS by NAC almost completely suppressing cell death. These results suggest that cotreatment with BZYQD and cisplatin might reverse cisplatin resistance by inducing ROS accumulation, which activates apoptosis and autophagy by oxidative stress. The combination of BZYQD and cisplatin may represent a novel approach in treatment for NSCLC and thus offer a new target for chemotherapy.

  12. The Practice of Mangrove Restoration in Qi'ao Island,Zhuhai%珠海市淇澳岛红树林恢复的实践

    Institute of Scientific and Technical Information of China (English)

    彭辉武; 郑松发; 朱宏伟

    2011-01-01

    红树林是生长在热带、亚热带海岸潮间带的木本植物群落.由于沿海经济的快速发展,中国的红树林面临着很大的威胁.运用人工种植的方法,进行红树林生态系统恢复是非常必要的.阐述了珠海市淇澳岛红树林恢复主要种植树种的选择、种植和抚育以及采取的工程措施.珠海市淇澳岛红树林恢复获得成功,该实践经验旨在为中国红树林恢复提供一些借鉴.%Mangrove is a special kind of forest growing in the intertidal zones of tropical and subtropical coastlines. Due to the fast development of coastal economy, the mangrove faces the destruction threat in China. So it is very urgent to restore the mangrove ecosystem by reforestation. In this paper, the selection of varieties of trees, cultivation and management as well as engineering measures taken in mangrove restoration in Qi'ao Island were represented. The mangrove restoration has succeeded, and the practical experiences deserved to be expanded in China.

  13. An extract of a formula used in the traditional chinese medicine (Buzhong Yi Qi Wan) alters the labeling of blood constituents with technetium-99m

    Energy Technology Data Exchange (ETDEWEB)

    Giani, Tania Santos; Paoli, Severo de; Brandao-Neto, Jose; Medeiros, Aldo da Cunha [Universidade Federal do Rio Grande do Norte (UFRN), Natal, RN (Brazil). Centro de Ciencias da Saude. Programa de Pos-graduacao em Ciencias da Saude]. E-mail: tgiani@gmail.com; Presta, Giuseppe Antonio; Maiworm, Adalgisa Ieda; Santos Filho, Sebastiao David; Fonseca, Adenilson de Souza da [Universidade do Estado do Rio de Janeiro (UERJ), RJ (Brazil). Inst. de Biologia Roberto Alcantara Gomes. Lab. de Radiofarmacia Experimental; Bernardo-Filho, Mario [Instituto Nacional de Cancer (INCa), Rio de Janeiro, RJ (Brazil). Centro de Pesquisa Basica

    2007-09-15

    Buzhong Yi Qi Wan (Buzhong) is a medicinal herb widely used in Traditional Chinese Medicine to treat the digestive and circulatory systems. Red blood cell and plasma proteins labeled with technetium-99m ({sup 99m}Tc) are used in nuclear medicine. The aim of this work was to investigate the effects of an aqueous Buzhong extract on the labeling of blood constituents with {sup 99m}Tc. Heparinized blood (Wistar rats) was incubated in vitro with different Buzhong extract concentrations and {sup 99m}Tc-labeling was performed. Plasma (P) and blood cells (BC) were separated and soluble (SF-P, SF-BC) and insoluble (IF-P, IF-BC) fractions were isolated. The radioactivity on blood constituents was determined and the percentage of incorporated radioactivity (%ATI) was calculated. Buzhong extract at the highest concentrations used altered significantly (p<0.05) the %ATI in blood constituents. Substances present in the Buzhong extract could alter the cellular membrane and/or generation of free radicals that have oxidant properties modifying the labeling of blood constituents with {sup 99}mTc. (author)

  14. Short-time QiBaoMeiRan Formula Treatment Exerts Estrogenic Activities without Side Effects on Reproductive Tissues in Immature Mice.

    Science.gov (United States)

    Xu, Ying; Ma, Xiao-ping; An, Jin-na; Zhang, Zi-jia; Ding, Jie; Qu, Ya-kun; Liu, Zhen-li; Lin, Na

    2015-12-08

    The Chinese herbal preparation QiBaoMeiRan formula (QBMR) displayed estrogenic effects in ovariectomized rats after long-term administration in a previous study. The uterus and vagina are negatively influenced by estrogens in hormone therapy. While QBMR is known to be a phytoestrogen, its estrogenic effects and safety on reproductive tissues after short-term administration and its mechanism via estrogen receptor (ER) pathway haven't been studied. Here, we characterized its estrogenic effects using immature mice together with in vitro studies for further molecular characterization. Immature mice were treated with QBMR at doses of 1.125, 2.25, and 4.5 g/kg for 7 days. 1.125 and 2.25 g/kg QBMR promoted the growth and development of uterus and vagina, and upregulated ERα and ERβ expression in reproductive tissues. QBMR had a stimulatory effect on proliferating cell nuclear antigen in vagina but not in uterus, and was without any influence on ki-67 antigen in uterus and vagina. QBMR significantly induced luciferase expression from the ERα/β-estrogen response element (ERE) luciferase reporter and upregulated ERα and ERβ expressions in MCF-7 cells, which were significantly inhibited by estrogen antagonist ICI182,780. This study demonstrated QBMR exerts estrogenic effects on reproductive tissues without side effects and through ER-ERE-dependent pathway.

  15. [Plasma metabonomic studies on the stable phase chronic obstructive pulmonary disease patients of Fei-qi deficiency syndrome and the Chinese materia medica intervention].

    Science.gov (United States)

    Liu, Zhi-gang; Li, Ze-geng; Peng, Bo

    2011-12-01

    By using the metabonomics method, to study the plasma metabonomics of the stable phase chronic obstructive pulmonary disease (COPD) patients of Fei-qi deficiency syndrome (FQDS), and of Chinese materia medica (CMM) intervention, thus exploring possibly existent biomarkers. Forty stable phase COPD patients of FQDS were recruited as Group A. Liuwei Buqi Capsule (LWBQC) was given to them as intervention. A healthy control group (Group B, 37 cases) was set up. The pulmonary function test was performed on patients in Group B and Group A before and after intervention. The plasma metabolites were detected using high performance liquid chromatography-mass spectrometry (HPLC-MS/MS). Statistical data were analyzed using principal component analysis (PCA) and partial least squares (PLS). The original spectrum and data of plasma metabonomics were compared between the two groups. The whole spectrum amino acid metabonomics tests were performed in the two groups. Compared with Group B, the pulmonary function significantly decreased before intervention in Group A (P plasma metabonomics, and potential markers could be detected. The intervention of the stable phase COPD patients of FQDS by Chinese medicine could brought positive changes in the metabolic profiling and amino acid metabolism.

  16. Mice Exposed to Chronic Intermittent Hypoxia Simulate Clinical Features of Deficiency of both Qi and Yin Syndrome in Traditional Chinese Medicine.

    Science.gov (United States)

    Chai, Chengzhi; Kou, Junping; Zhu, Danni; Yan, Yongqing; Yu, Boyang

    2011-01-01

    Deficiency of both Qi and Yin Syndrome (DQYS) is one of the common syndromes in traditional Chinese medicine (TCM), mainly characterized by tiredness, emaciation, anorexia, fidget, palpitation and rapid pulse, and so forth. Currently, there is no available animal model which can reflect the clinical features of this syndrome. In the present paper, we observed the time-course changes of whole behavior, body weight, food intake, locomotive activity and electrocardiogram in mice exposed to chronic intermittent hypoxia for 6 weeks, and measured bleeding time at last according to the clinical features of DQYS and one key pathological factor. The results showed that the mice exposed to intermittent hypoxia for certain time presented lackluster hair, dull looking hair, resistance, attacking, body weight loss, food intake decline, locomotive activity decrease, heart rate quickening and T wave elevating, which were similar to the major clinical features of DQYS. Meanwhile, bleeding time shortening was also found, which was consistent with the clinical fact that DQYS often accompanied with blood stasis. The possible explanation was also outlined according to the available literature. Such findings suggested chronic intermittent hypoxia could induce similar symptoms and signs in mice accorded with the clinical features of DQYS, which provided a suitable animal model for evaluation of drugs for the treatment of this syndrome and further exploration of pathological process or correlation of the syndrome and related diseases.

  17. 朱广旗教授治疗小儿癫痫病经验%Experience of Professor ZHU Guang-qi for treating children’s epilepsia

    Institute of Scientific and Technical Information of China (English)

    陶奕汐; 朱广旗

    2013-01-01

    Epilepsia is a common disease of children’s systema nervosum, which can cause many kinds of chronic brain diseases and damage brain function if breaks out frequently. Therefore, it becomes the main prevention and cure mental disorder. Professor ZHU Guang-qi has worked as a doctor for more than 30 years, and has abundant experience for treating epilepsia. He summarizes several kinds which has notable efficacy.%  癫痫为小儿神经系统常见疾病之一,是多种病因引起的慢性脑疾病;长期、频繁地发作可损害脑功能,因此该病成为全球重点防治的神经精神疾病。吾师从医30余年,学验颇丰,在治疗小儿癫痫中积累了丰富经验,总结出熄风豁痰、补脾肾等治痫方法,临床疗效显著。

  18. Mice Exposed to Chronic Intermittent Hypoxia Simulate Clinical Features of Deficiency of both Qi and Yin Syndrome in Traditional Chinese Medicine

    Directory of Open Access Journals (Sweden)

    Chengzhi Chai

    2011-01-01

    Full Text Available Deficiency of both Qi and Yin Syndrome (DQYS is one of the common syndromes in traditional Chinese medicine (TCM, mainly characterized by tiredness, emaciation, anorexia, fidget, palpitation and rapid pulse, and so forth. Currently, there is no available animal model which can reflect the clinical features of this syndrome. In the present paper, we observed the time-course changes of whole behavior, body weight, food intake, locomotive activity and electrocardiogram in mice exposed to chronic intermittent hypoxia for 6 weeks, and measured bleeding time at last according to the clinical features of DQYS and one key pathological factor. The results showed that the mice exposed to intermittent hypoxia for certain time presented lackluster hair, dull looking hair, resistance, attacking, body weight loss, food intake decline, locomotive activity decrease, heart rate quickening and T wave elevating, which were similar to the major clinical features of DQYS. Meanwhile, bleeding time shortening was also found, which was consistent with the clinical fact that DQYS often accompanied with blood stasis. The possible explanation was also outlined according to the available literature. Such findings suggested chronic intermittent hypoxia could induce similar symptoms and signs in mice accorded with the clinical features of DQYS, which provided a suitable animal model for evaluation of drugs for the treatment of this syndrome and further exploration of pathological process or correlation of the syndrome and related diseases.

  19. Viabilidade da estimativa de QI a partir dos subtestes Vocabulário e Cubos da WAIS-III Viability of IQ estimates based on Vocabulary and Block Design WAIS-III subtests

    Directory of Open Access Journals (Sweden)

    Flávia Wagner

    2010-08-01

    Full Text Available Objetivou-se avaliar a viabilidade de estimar o Quociente de Inteligência (QI de adultos por meio de duas estratégias que utilizam uma forma curta constituída pelos subtestes Vocabulário e Cubos da Escala Wechsler de Inteligência para Adultos (WAIS-III. Participaram do estudo 77 homens e mulheres, com idade média de 39,1 anos (dp=13,4. Foi aplicada a WAIS-III e questionários para cumprir os critérios de inclusão dos participantes sem prejuízos neurológicos e psiquiátricos. Para avaliar a concordância entre as duas estratégias de estimar o QI, utilizou-se o método estatístico proposto por Bland e Altman. Como resultado, encontrou-se que as estimativas de QI geradas pelas duas estratégias apresentam concordância com a medida do QI realizada pela aplicação da escala completa apenas em alguns dos casos avaliados. Sugere-se cautela na utilização dessas estratégias para estimar o QI de adultos.The aim of this study was to evaluate the feasibility of estimating the Intelligence Quotient (IQ in adults based on two strategies that use Vocabulary and Block Design subtests of Wechsler Adult Intelligence Scale (WAIS-III. Seventy-seven men and women participated of the study, with mean age of 39.1 (sd=13.4. WAIS-III subtests were administered and questionnaires were used to verify inclusion criteria for participants without neurological or psychiatric impairments. A statistical method proposed by Bland and Altman was used to evaluate the agreement between both strategies to estimate IQ. Results suggest that IQ estimates derived from both strategies only agree with the IQ derived from the full battery in a few cases of the sample. Considering these findings, caution is suggested when using these strategies to estimate adults' IQ.

  20. 祁东黄花菜多糖的提取及含量测定%Extraction and Determination of Polysaccharides from Daylily of QiDong

    Institute of Scientific and Technical Information of China (English)

    周纪东; 李余动

    2015-01-01

    The polysaccharides were extracted in hot water and isolated by ethanol from Daylily of QiDong, then determined. The content of polysaccharides was determined by spectrophotometric method with phenol sulfuric acid as coloring reagent. Based on the results of single factor tests, the optimum parameters of polysaccharides extraction were studied by orthogonal tests. The re-sults showed that the optimal extraction temperature, time, the ratio of liquid to solid and extraction times were 80℃, 3h, 20:1 and 2 times, respectively. Under this extraction method, the average rate of polysaccharides extraction was 28.36%, RSD=2.04%, the average content of polysaccharides was 14.92%, RSD=2.85%, and the average recovery rate was 100.65%, RSD=3.28%.%以祁东黄花菜为原料,采用水提醇沉法提取出黄花菜多糖并进行含量测定。多糖含量测定方法为苯酚-硫酸法。在单因素试验的基础上,通过正交试验确定最佳浸提工艺条件。结果表明,黄花菜多糖最佳浸提条件为液固比20:1,80℃保温3h,浸提2次。按此浸提,多糖平均提取率为28.36%,RSD=2.04%;多糖平均含量为14.92%,RSD=2.85%;平均回收率为100.65%,RSD=3.28%。

  1. Summary of 32 Patients with Cardiac Syndrome X Treated by TCM Therapy of Regulating Qi Relieving Chest Stuffiness and Promoting Blood Circulation

    Institute of Scientific and Technical Information of China (English)

    MAO Jing-yuan; ZHAO Gui-feng; WANG Zhan-wu; MA Xue-peng; ZHANG Zhen-peng; LI Ming; SHAO Lei; ZHAO Chun-yan; GE Yong-bin; WANG Heng-he; WANG Qiang; ZHANG Yun; YU Dong-ling; ZHANG Yu; HUANG Qi; ZHAO Zhi-qiang

    2007-01-01

    Objective:To evaluate the clinical effect of Liqi Kuanxiong Huoxue method(理气宽胸活血,LKH,traditional Chinese medicine,TCM therapeutic method for regulating qi,relieving chest stuffiness and promoting blood circulation) in treating patients with cardiac syndrome X (CSX).Methods:The prospective,non-randomized controlled study was conducted on 51 selected patients with CSX,who were non-randomly assigned to 2 groups,the treated group treated with LKH in addition to the conventional treatment(32 patients),and the control group treated with conventional treatment(19 patients)like nitrate,diltiazem hydrochloride,etc.The treatment course was 14 days.The changes of such symptoms as angina pectoris,TCM syndrome and indexes of treadmill exercise test before and after treatment were observed.Results:After treatment,such symptoms as chest pain and stuffy feeling and palpitation in the treated group were improved more than those in the control group(P<0.05);the total effective rate on angina pectoris and TCM syndrome in the treated group was better than that in the control group(P<0.05).The treadmill exercise test showed that the maximal metabolic equivalent(Max MET),the time of angina onset and ST segment depression by 0.1 mV were obviously improved after treatment in both groups,but the improvement in the treated group was better than that in the control group respectively (P<0.05).Conclusion:The LKH method could reduce the frequency of angina attacks and improve the clinical condition of patients with CSX.

  2. 孟安琪教授治疗继发性闭经经验%Professor MENG An-qi Treats the Experience Which the Secondary Stops Menstruating

    Institute of Scientific and Technical Information of China (English)

    张莹

    2011-01-01

    孟安琪教授从医20余载,临床经验丰富,对于继发性闭经的治疗从肾入手,以补肾为根本,调血为其标,善调气血,以调为主,养血为先,补肾为要,灵活运用四物汤,临证中,对于四物汤用之恰到好处,四物汤中之四物有着独到的应用见解,且在保持其调经的前提下,灵活改变各药剂量及增减药味以达到改变其主治作用或者增加兼证的治疗方面,临床中治疗继发性闭经效果显著.%Professor MENG An-qi from the medical 20 space remainings for freight, the clinical rich experience, the treatment which stops menstruating regarding the secondary obtains from the kidney, take invigorates the kidney as the basis, adjusts the blood for its sign, the friendly accent vitality, moves primarily, raises the blood for first, invigorates the kidney to want, utilizes four soup nimbly, near the card, uses regarding four soup just right, fourth the thing in four soup have the original application opinion, and in maintains under the premise which it regulates menstruation, changes various medicament quantity and the fluctuation medicine position nimbly achieves changes it to mainly treat the function or to increase the concurrently card the treatment aspect, clinical treats the sequential menopause effect to be remarkable.

  3. [Effect of medicines for activating blood and reinforcing Qi on angiogenesis in infarcted myocardium edge area of acute myocardial infarction model in rats].

    Science.gov (United States)

    Zang, Wen-Hua; Yin, Shen-Hua; Tang, De-Cai; Li, Bing-Bing

    2014-03-01

    To study the effect of medicines for activating blood and reinforcing Qi on the number of new micro-vessels and the protein expressions of VEGF and bFGF in the infarcted myocardium edge area of acute myocardial infarction (AMI) model in rats. The AMI model of rats was established. After the successful model establishment, rats were randomly divided into the sham-operated group, the model group, the Danshen-Huangqi (1 : 2) group, the Danshen-Huangqi (1 : 1) group, the Chuanxiong-Huangqi (1 : 2) group, the Danshen group, the Chuanxiong group, the Chishao group and the Shexiang Baoxin pill group, with five rats in each group. Rats in each medicated group were orally administered with drugs as per 13.5 g x kg(-1) x d(-1) once everyday for three weeks. The immunohistochemical SP method was adopted to detect the expression of vWF in myocardial tissues, and count the number of micro-vessels (MVC). The protein expression of VEGF and bFGF in myocardial tissues were determined by Western blot. The new micro-vessels stained by vWF factor could be found in the infarcted myocardium edge area of the sham-operated group, the model group and all of medicated groups. The sham-operated group show unobvious new micro-vessels in myocardial tissues. A small amount of new micro-vessels could be seen in the infarcted myocardium edge area of the model group. Whereas a larger number of micro-vessels could be seen in the infarcted myocardium edge area of all of medicated groups. The differences between the sham-operated group and the model group had statistical significance (P effect in promoting angiogenesis. Their mechanism for promoting angiogenesis may be related to the improvement of the protein expressions of VEGF and bFGF, so as to increase the contents of VEGF and bFGF and promote the angiogenesis of new vessels.

  4. QI em pacientes com hidrocefalia e mielomeningocele: implicações do tratamento cirúrgico IQ in hydrocephalus and myelomeningoceles: implications of surgical treatment

    Directory of Open Access Journals (Sweden)

    JEAN-LUC FOBE

    1999-03-01

    Full Text Available Mieloningocele ocorre em frequência aproximada de 0,4 por 1000 nascidos vivos e está associada a hidrocefalia em 85% a 90%, sendo as avaliações sobre cognição esparsas na literatura. Quarenta e cinco crianças com hidrocefalia derivada e mielomeningocele foram analisadas quanto ao QI, que foi estatisticamente correlacionado com o nível motor, idade da primeira derivação, número de revisões, infecção e perímetro cefálico. A idade média foi 7,5 anos (3 a 15 anos, 16 eram do sexo masculino e 29 eram do sexo feminino. Três (6,6% obtiveram escore de QI >110, 11 (24,5% entre 100-110, 8 (17,7% entre 85-100, 16 (35,5% entre 70-85 e 7 (15,5% entre 50-70. O QI correlacionou-se diretamente com o nível motor, sendo o resultado cognitivo melhor, em ordem decrescente, nos níveis sacral (t 0,0055, lombar baixo (t 0,0119 e lombar alto (t 0,0226. Houve melhor desempenho cognitivo nas crianças operadas até 7 dias de vida (t 0,0099, decrescendo progressivamente o resultado a partir do primeiro mês, não existindo diferença significativa entre 7 a 31 dias (t 0,1013. Houve pior resultado no grupo que apresentou infecção do sistema de derivação (t 0,0146. O prognóstico foi progressivamente pior de acordo com o número de revisões. O melhor resultado foi encontrado nas crianças com perímetro cefálico na média (t 0,0115; resultado intermediário entre --1 DP (desvio padrão e a média (t 0,0130 e entre a média e +1DP (t 0,0256. Os piores resultados cognitivos foram encontrados nos extremos >1DP (t 0,0269 e Myelomeningocele occurs in 0.4 for 1000 neonates and is associated with hydrocephalus in 85-90%, and reports on cognition are sparsely found in literature. Forty five children with treated hydrocephalus and myelomeningocele were studied in regard of IQ, and statistically correlated to functional motor level, age of the first shunt, number of revisions of shunt, infection of the shunt and circumference of the head. The medium age was

  5. Effect of Electroacupuncture at Gan Shu, Qi Men on Changes of Behaviors and Related Hormones of Hypothalamus - Pituitary - Adrenal Axis in Rats with Syndrome of Stagnation of Liver - Qi%电针肝俞、期门对肝气郁结模型大鼠行为学及HPA轴相关激素的影响

    Institute of Scientific and Technical Information of China (English)

    刘子旺; 赵海滨; 张秀静; 单保慈; 刘华; 贺立娟

    2011-01-01

    目的:探讨电针对肝气郁结模型大鼠行为学影响及下丘脑-垂体-肾上腺(HPA)轴相关激素的调节作用.方法:将Wistar大鼠30只随机分为正常对照组、肝郁模型组、电针治疗组,通过开野实验( Open - Field Test)及蔗糖水消耗实验进行大鼠行为学检测,运用ELISA法检测大鼠血清促肾上腺皮质激素释放激素(CRH)、皮质酮(CORT)含量,3组之间进行比较.结果:与正常组相比,模型组Open -Field Test水平运动得分和垂直运动得分明显减少,蔗糖水偏嗜度明显减少,血清CORT、CRH的含量明显升高,而电针明显增加模型大鼠的水平得分、垂直得分及蔗糖水偏嗜度,并可阻抑血清CRH、CORT的过度分泌.结论:肝气郁结大鼠存在活动度降低、探究行为减少、快感缺失和HPA轴亢进,电针肝俞、期门可抑制CRH、CORT的过度分泌,缓解HPA轴亢进,外在体现为对模型大鼠行为学的改善.%Objective:To investigate the effect of electroacupuncture (EA) on changes of behaviors and some related hormones of the hypothalamus - pituitary - adrenal ( HPA) axis in rats with stagnation of liver - qi syndrome. Methods:The rats were randomly divided into three groups; normal group, model group, EA group, n = 10. We judged the behavioral changes of model rats and the behavioral action of EA in treating the stagnation of liver - qi syndrome through Open - Field Test and partial addicted to sugar water test. The content of ad-renocorticotropic hormone - releasing hormone ( CRH ) and serum corticosterone ( CORT) were measured by ELJSA method. Results:The horizontal movement scores and vertical movement scores of rats in model group both significantly reduced compared with the normal group (P <0.01) ,as well as the degree of partial addicted to sugar water of model group rats decreased significantly ( P <0.01) . The content of CRH and CORT in serum of model group rats were significantly higher(P <0. 01). The horizontal movement

  6. Assessment of effects of a formula used in the traditional Chinese medicine (Buzhong Yi Qi Wan on the morphologic and osmotic fragility of red blood cells Determinação dos efeitos de uma fórmula usada na medicina tradicional chinesa (Buzhong Yi Qi Wan na morfologia a fragilidade osmótica de hemácias

    Directory of Open Access Journals (Sweden)

    Tania S. Giani

    2007-12-01

    Full Text Available Buzhong Yi Qi Wan (BYQW is a combination of some medicinal herbs widely used in traditional Chinese medicine to treat blood, spleen and stomach disorders. Morphometric analysis and osmotic fragility assay have been used to evaluate changes on membrane integrity of red blood cells. The aim of this work was to evaluate the effect of an aqueous BYQW extract on the morphology and osmotic fragility of red blood cells. Blood samples were treated with BYQW extract, quantitative/qualitative morphological analysis and osmotic fragility assay were carried out against control groups treated with saline. The data obtained indicated no modification on morphology but osmotic fragility assay suggested a significant (pBuzhong Yi Qi Wan (BYQW é uma combinação de algumas ervas medicinais amplamente usada na medicina tradicional chinesa para tratar o sangue, baço e desordens do estômago. A análise morfométrica e o ensaio de fragilidade osmótica têm sido usados para avaliar alterações na integridade da membrana de hemácias. O objetivo deste trabalho foi avaliar os efeitos de um extrato aquoso de BYQW na morfologia e na fragilidade osmótica de hemácias. Amostras sangüíneas foram tratadas com o extrato de BYQW, análise morfológica quantitativa/qualitativa e o ensaio de fragilidade osmótica foram realizados e comparados com grupo controle tratado com salina. Os dados obtidos indicaram ausência de modificações na morfologia, mas o ensaio de fragilidade osmótica sugeriu um aumento significativo (p<0,05 da hemólise em hemácias isoladas de sangue tratado com extrato aquoso de BYQW. Em conclusão, o extrato aquoso de BYQW poderia afetar a integridade da membrana diminuindo a resistência osmótica sem alterar a forma das hemácias.

  7. Zhang Huadong's Experiences in the Treatment of Sjogren Syndrome Based on the Theory of Liver and Lung Qi Activity%张华东从肝肺气机论治干燥综合征经验

    Institute of Scientific and Technical Information of China (English)

    桑永兵; 刘颖; 鲁构峰; 赵瑞英; 邓俊花; 张华东

    2016-01-01

    Sjogren syndrome( SS)results from the dysfunction of body fluids transformation and dis-tribution and is classified into the categories of“dryness syndrome”,“dryness toxin”and“dryness Bi syn-drome”in traditional Chinese medicine. Prof. Zhang Huadong accumulated rich clinical experiences in the treatment of SS and the treating theory of liver and lung qi activity is one of the characteristics. Prof. Zhang believed that the treatment of SS should focus on regulating liver and lung qi activity. Dysfunction of liver and lung qi in ascending and descending leads to deficiency of qi,blood and body fluids and distribution impair-ment,which is one of the key causative factors of the disease. Hence,the principles of treatment are regulating liver and lung qi ascending and descending and normalizing the distribution of qi,blood and body fluids. Based on the pattern/syndrome differentiation in clinic,the disease is differentiated as the mental hyperactivi-ty restricting the wood,the wood fire restricting the mental,the failure of metal to restrict the wood,the mental dryness burning up the wood,the wood dryness disturbing the mental,the steaming up of the mental and wood,etc. The treatment methods are modified in accordance with the symptoms. This therapy is widely used in clinical practice and has achieved the significant efficacy.%干燥综合征在中医看来,是津液化生与运行敷布失常,根据其临床表现当属“燥证”“燥毒”“燥痹”等范畴。张华东教授在治疗干燥综合征多年临床经验中,从肝肺气机论治是其特色之一,认为论治干燥综合征可从调理肝肺气机入手,肝肺气机升降失调引起气血津液盈亏、输布失常是本病发病的关键之一,治疗上应调理肝肺气机升降,平和气血津液输布。具体在临床辨证的分型中,有金亢制木、木火刑金、金不制木、金涸燎木、木枯扰金、金蒸木焖等等,实际中随证而治,广泛应用,疗效卓著。

  8. 温针灸治疗脾胃气虚型功能性消化不良疗效评价%The Therapeutic Evaluation of Warm Needling Method for Spleen Stomach Qi Deifciency Type of Functional Dyspepsia

    Institute of Scientific and Technical Information of China (English)

    赵莉; 赵欲晓

    2016-01-01

    Objective To study the effect of warm needling treatment for spleen stomach qi deficiency type of functional dyspepsia.Methods58 patients with spleen and stomach qi deifciency type of functional dyspepsia in our hospital, were randomly divided into two groups, each 29 cases. Giving oral administration of domperidone tablets for the control group, the treatment group used the warm needling method based on the above treatment, to compare the treatment effect of them.Results The total effective rate of the treatment group was higher than the control group. There was statistical significance (P<0.05).Conclusion The warm needling treatment for spleen stomach qi deifciency type of functional dyspepsia is able to increase the total effective rate of treatment and improve the living standard of patients.%目的:研究温针灸治疗脾胃气虚型功能性消化不良的效果。方法选择来我院治疗脾胃气虚型功能性消化不良的患者58例,随机将其分成两组,每组29例。对照组口服多潘立酮片,实验组在上述治疗基础上实施温灸治疗。对比两组治疗效果。结果实验组总有效率高于对照组,差异有统计学意义(P<0.05)。结论采用针灸治疗脾胃气虚型功能性消化不良可以提高治疗的总有效率,改善患者生活水平。

  9. 重构中医学气-阴阳-五行结构图%Reconstructing the Structural Drawing of Qi-Yin and Yang-Five Elements in TCM

    Institute of Scientific and Technical Information of China (English)

    贾春华; 郭瑨; 朱丽颖; 侯星宇

    2014-01-01

    Objective:Trying to explain the constitution,physiology and pathology of human beings according to the newly reconstructed structural drawing of Qi-Yin and Yang-Five Elements in TCM.Methods:The structural drawing was created by integrating the meaning contained within the article of The Explanation for the Tai Ji Diagram written by Dunyi Zhou with the structure of DNA double helix.Re-sults:Reconstructed a structural model of Qi-Yin and Yang-the Five Elements double helix.Conclusion:A new and intuitive structural drawing was reconstructed by integrating all the Qi,Yin and Yang and the Five Elements.And it can be used to explain the constitution, physiology and pathology of human beings.%目的:重构中医学气-阴阳-五行结构图,预期以此图解释人体体质与生理病理。方法:取周敦颐的《太极图说》太极、阴阳、五行宇宙演化进程之意,以 DNA 双螺旋结构的分子模型之形,将两者结合进行构建。结果:构建出一个具有双螺旋结构的中医学气-阴阳-五行结构模型。结论:整合了以往的阴阳、五行图,提供了一幅直观的气-阴阳-五行融合后的结构图,此模型图可以对人体质、生理病理等方面做出结构上的解释。

  10. Lipidomics study of plasma phospholipid metabolism in early type 2 diabetes rats with ancient prescription Huang-Qi-San intervention by UPLC/Q-TOF-MS and correlation coefficient.

    Science.gov (United States)

    Wu, Xia; Zhu, Jian-Cheng; Zhang, Yu; Li, Wei-Min; Rong, Xiang-Lu; Feng, Yi-Fan

    2016-08-25

    Potential impact of lipid research has been increasingly realized both in disease treatment and prevention. An effective metabolomics approach based on ultra-performance liquid chromatography/quadrupole-time-of-flight mass spectrometry (UPLC/Q-TOF-MS) along with multivariate statistic analysis has been applied for investigating the dynamic change of plasma phospholipids compositions in early type 2 diabetic rats after the treatment of an ancient prescription of Chinese Medicine Huang-Qi-San. The exported UPLC/Q-TOF-MS data of plasma samples were subjected to SIMCA-P and processed by bioMark, mixOmics, Rcomdr packages with R software. A clear score plots of plasma sample groups, including normal control group (NC), model group (MC), positive medicine control group (Flu) and Huang-Qi-San group (HQS), were achieved by principal-components analysis (PCA), partial least-squares discriminant analysis (PLS-DA) and orthogonal partial least-squares discriminant analysis (OPLS-DA). Biomarkers were screened out using student T test, principal component regression (PCR), partial least-squares regression (PLS) and important variable method (variable influence on projection, VIP). Structures of metabolites were identified and metabolic pathways were deduced by correlation coefficient. The relationship between compounds was explained by the correlation coefficient diagram, and the metabolic differences between similar compounds were illustrated. Based on KEGG database, the biological significances of identified biomarkers were described. The correlation coefficient was firstly applied to identify the structure and deduce the metabolic pathways of phospholipids metabolites, and the study provided a new methodological cue for further understanding the molecular mechanisms of metabolites in the process of regulating Huang-Qi-San for treating early type 2 diabetes.

  11. Clinical Observation on Replenishing Spleen Qi and Nourishing Yin Method of Gastric Precancerous Lesions%益气健脾养阴法治疗胃癌前病变临床观察

    Institute of Scientific and Technical Information of China (English)

    谢晶日; 李柏

    2013-01-01

    目的:观察研究益气健脾养阴法治疗胃癌前病变的临床疗效.方法:将48例患者随机分为治疗组24例和对照组24例.治疗组给予益气健脾养阴方,每日1剂;对照组给予胃复春片,每日3次,每次4片,饭前空腹服用.3个月为1个疗程,均治疗2个疗程.结果:治疗后治疗组的临床症状、胃镜及病理学表现均明显好于对照组(P<0.05).结论:益气健脾养阴法治疗胃癌前病变有显著疗效.%Objective:To observe and study the curative effect of replenishing spleen qi and nourishing Yin method of gastric precancerous lesions.Methods:48 patients were randomly divided into treatment group (24 cases) and control group (24 cases).The treatment group was given the replenishing spleen qi and nourishing Yin therapy once a day.The control group was given Weifuchun Tablet three times a day and four tables for once.Three months was for a period of treatment.There were two treatment courses.Results:After treatment,the clinical symptoms,gastroscope and pathology performance of treatment group were significantly better than those of the control group (P < 0.05).Conclusion:The replenishing spleen qi and nourishing Yin method treatment of gastric precancerous lesion has remarkable curative effect.

  12. A ginástica terapêutica e preventiva chinesa Lian Gong/Qi Gong como um dos instrumentos na prevenção e reabilitação da LER/DORT

    OpenAIRE

    Gutembergue Livramento; Tânia Franco; Alaíde Livramento

    2010-01-01

    Este ensaio traz elementos da medicina ocidental, da medicina tradicional chinesa e da sociologia do trabalho para reflexão sobre o Qi Gong - exercícios terapêuticos, um dos pilares da Medicina Tradicional Chinesa (MTC) - como importante meio de prevenção da LER/DORT e recuperação da saúde. Considerando a natureza interdisciplinar e diversos níveis de prevenção, aborda aspectos sociológicos sobre as condições de trabalho frequentemente relacionadas com este tipo de adoecimento e categorias de...

  13. Research of DNA Damage Induced by Free Radicals in Syndrome of Spleen Qi Deficiency%脾气虚证自由基导致DNA损伤变化探析

    Institute of Scientific and Technical Information of China (English)

    丛培玮; 尚冰; 许南阳; 史冰洁; 王蕊芳

    2013-01-01

    Objective: This research was to explore the changing rule of DNA attacked hy free radicals and oxidative damage in rats with spleen qi deficiency, understanding the role of spleen qi deficiency in the development process of spleen disease and providing experimental evidence for further research. Methods: Fatty diet plus over fatigue method was used to establish the model for 14 days, and the last 24 h urine samples were taken to measure the content of 8-OHdG, and the SOD, GSH-Px, T-AOC and MDA contents were measured in brain cortex and serum. Results: In serum and cerebral cortex, the contents of SOD, GSH-Px, T-AOC and MDA in the model group showed a significant difference ( P<0.05 ) .The 8-OHdG in the urine samples of the model group was increased significantly ( P<0.05 ) .Conclusion : There is a clear reduction of antioxidant enzyme activities and free radical damage in spleen qi deficiency model, but the spleen qi deficiency state in which stage of the spleen diseases is needed to be understood in-depth studies.%目的:探讨脾气虚状态下模型大鼠体内DNA受到自由基攻击和氧化损伤的程度,了解脾气虚在中医脾病发展过程中的地位,进一步为脾气虚证提供实验学依据.方法:采用“饮食不节+疲劳过度”复合方法造模14天后,取大鼠最后24 h尿样测定8-OHdG的含量,取脑皮质和血清测定SOD、GSH-Px、T-AOC、MDA的含量.结果:脾气虚模型组大鼠血清和脑皮质中SOD、GSH-Px、T-AOC和MDA含量与正常组相比均有显著差异(P<0.05).模型组尿样中8-OHdG含量也有明显上调趋势(P<0.05)结论:脾气虚模型大鼠体内存在着明显的自由基损伤和抗氧化酶活性的降低,但脾气虚状态处于脾病全程的何种阶段尚需深入研究了解.

  14. The clinical study of QiRen anti-wrinkle cream geting rid of wrinkles%芪人抗皱霜祛皱作用的临床研究

    Institute of Scientific and Technical Information of China (English)

    唐志铭; 翟晓翔; 张翠侠; 陈向辉; 李敬果; 陈苏; 曹广法

    2011-01-01

    Objective To investigate the clinical efficacy of QiRen anti-wrinkle cream getting rid of wrinkles. Methods the 90 subjects met the inclusion criteria were randomly divided into experimental and control groups. On the skin test sites, the two group Separately coated with QiRen anti-wrinkle cream and ordinary wrinkle cream twice a day morning and evening, for the period of 40 days.Before and after testing, the subjects were pictured for evaluating the skin wrinkle grade and points.and copy skin wrinkles model with the silicone rubber for analysis and processing by the image analysis software. Results Clinical observations show that the QiRen anti-wrinkle cream can reduce the wrinkles credits, the wrinkle depth and the skin roughness, and better than the control group (P<0.01). Conclusion QiRen anti-wrinkle cream who has a good wrinkle cosmetic effect is a safe and effective beauty product and did not find any adverse reaction.%目的:探讨芪人抗皱霜祛除皮肤皱纹的临床疗效.方法:将90例符合纳入标准的受试对象随机分为试验组和对照组.试验组使用芪人抗皱霜,对照组使用普通祛皱霜,分别于皮肤皱纹测试部位外涂,每日早晚各涂一次,使用周期为40天.试验前后均拍照进行皮肤皱纹等级及积分评价,同时用硅橡胶复制皮肤皱纹模型,应用图象分析软件对其进行分析处理.结果:临床观察结果表明,芪人抗皱霜能够降低受试对象的皱纹积分,降低皮肤皱纹深度及皮肤皱纹粗糙度,并优于对照组(P<0.01).结论:芪人抗皱霜有较好的祛皱美容作用,未发现任何不良反应,不失为一种安全有效的美容产品.

  15. Understanding the substance of the disturbance of Qi activity from the aspect of brain-gut interaction%从脑肠关系认识气机紊乱的实质

    Institute of Scientific and Technical Information of China (English)

    岳妍

    2012-01-01

    The body's Qi's circular motion is based on the ascending of the kidney water and the descending of the heart fire. The liver and spleen help the ascending of the kidney water to nourish the heart Yin,and the lung and stomach help the descending of the heart fire to replenish and warm the kidney Yang. The spleen and the stomach are the key of the ascending and descending of Qi movement. The relationship between the liver and spleen are based on the modern biology brain-gut axis. The neuroen-dncrine-imiminity regulatory network is the core of the brain-gut axis. In this network a variety of neuro-transmitters, neuropeptides, hormones and immunity factors are interacting and regulating to keep the constitution of the network on the whole and to maintain the balance and stability of the body's internal environment and physiological functions. It can be reckoned that the Qi in TCM may have a relationship with the neuroen-docrine-immunity network and that the nature of the disorder of the Qi movement is the disorder of the network's function.%人体气机圆运动是以“肾水升、心火降”为根本,肝脾助肾水以温升,上济心阴,肺胃助心火以凉降,下温肾阳,中焦脾胃是气机升降的枢纽.肝脾相关的现代生物学基础为脑-肠轴失衡.脑-肠轴是以神经-内分泌-免疫调节网络为核心,在这个网络中多种神经递质、神经肽、激素以及免疫因子所介导的相互作用与调节,保持着该网络在整体水平上构成和维持机体内环境及生理功能的平衡和稳定.由此推测中医学的“气”可能与神经-内分泌-免疫调节网络功能有关,气机紊乱的实质即该网络功能失调.

  16. 《黄帝内经》气血经络概念解析%Analysis on the concepts of qi, blood and meridians in Huangdi Neijing (Yellow Emperor's Canon of Internal Classic

    Institute of Scientific and Technical Information of China (English)

    张维波

    2013-01-01

    对《黄帝内经》中涉及气血经络的一系列概念进行解析,通过分析《黄帝内经》描述的各概念之间的关系,结合后人的注释和现代科学知识,逐步用已知的概念阐明未知概念.指出经络是对血脉、分肉、筋等概念的分级概念,营卫是气血的部位层次概念,气在不同的位置和条件下有着不同的名称,是人体体液的不同表现形式,将气血经络概念用列表和图示的形式表示出来,成为层次分明的概念体系,为理解《黄帝内经》的思想提供了帮助.%Concepts of qi,blood,meridians and collaterals in Huangdi Neijing (Yellow Emperor's Canon of Internal Classic) were analyzed systematically based on their relationships described in the classic.With the assistant of the annotation of the later generations and the modern scientific knowledge,the unknown concepts were gradually replaced by the known concepts.It is found that meridians and collaterals are the grading concepts for vessels,boundaries between muscles,tendons,etc.Ying (nutrient) and Wei (defensive) are the concepts of site and level description of qi and blood.And qi has different names at different positions and conditions which is held as various states of body fluid.In this article,the concepts of meridians,qi and blood were demonstrated in the forms of tables and figures.It developed gradually into a conceptual system with clear levers which benefits people to understand Huangdi Neijing (Yellow Emperor's Canon of Internal Classic).

  17. 益气清热活血法辨治慢性萎缩性胃炎初探%Preliminary Discussion on Therapy of Benefiting Qi and Clearing Heat for Promoting Blood Circulation in Treating Chronic Atrophic Gastritis

    Institute of Scientific and Technical Information of China (English)

    张征波

    2016-01-01

    Objective To explore mechanism and clinical experience on therapy of benefiting qi and clearing heat for promoting blood circulation in treating chronic atrophic gastritis .Methods Through the study of literature and clinical practice , the pathological factors of CAG include exogenous, diet, emotion and fatigue.The key pathogenesis is insufficiency of the spleen , blood stasis caused by deficiency , then deficiency , heat and blood stasis were coexisted .The therapy of benefiting qi and clearing heat for promoting blood circulation is used .Result The therapy of benefiting qi and clearing heat for promoting blood circulation in treating chronic atrophic gastritis has obtained better therapeutic effect .Conclusion The therapy of benefiting qi and clearing heat for promoting blood circulation can effectively reduce the risk of the disease to the development of gastric cancer , and provide new ideas for the clinical treatment of CAG and the prevention of gastric cancer .%目的:探索健脾益气清热活血通络法(以下简称益气清热活血法)治疗慢性萎缩性胃炎的机理及临床经验。方法通过研读文献及临床实践,总结慢性萎缩性胃炎的病理因素多是外感、饮食、情志、劳倦,病机关键以脾虚为本,瘀热为标,因虚致瘀,虚、热、瘀并存。以此为理论指导,采用益气清热活血法治疗本病。结果临床采用益气清热活血法治疗本病取得良好疗效。结论益气清热活血法可有效降低本病向胃癌发展的风险。为临床治疗慢性萎缩性胃炎及预防胃癌的发生提供新思路。

  18. To compare the efficacy of two kinds of Zhizhu pills in the treatment of functional dyspepsia of spleen-deficiency and qi-stagnation syndrome:a randomized group sequential comparative trial

    Directory of Open Access Journals (Sweden)

    Huang Luqi

    2011-07-01

    Full Text Available Abstract Background In Traditional Chinese Medicine (TCM theory, functional dyspepsia (FD can be divided into different syndromes according to different clinical symptoms and signs, and the most common one is spleen-deficiency and qi-stagnation syndrome that can be treated by Chinese traditional patent medicine ---- two kinds of Zhizhu pills, between which the primary difference in ingredients is that one contains immature orange fruit of Citrus aurantium L.(IFCA and the other contains that of Citrus sinensis Osbeck (IFCS. The trial's objective was to compare the efficacy of two kinds of Zhizhu pills on symptom changes in patients with FD of spleen-deficiency and qi-stagnation syndrome. Methods A randomized, group sequential, double-blinded, multicenter trial was conducted in patients with FD of spleen-deficiency and qi-stagnation syndrome at 3 hospitals in Beijing between June 2003 and May 2005. Participants were randomly allocated into two groups (IFCA group and IFCS group in a 1:1 ratio, and respectively took one of the two kinds of Zhizhu pills orally, 6 g each time, 3 times a day, for 4 weeks. Statistical analysis was performed with use of a group sequential method, the triangular test (TT. Results A total of 163 patients were randomized, and 3 patients were excluded from analysis because of early dropouts, leaving 160 patients (IFCA group: n = 82; IFCS group: n = 78 for statistical analysis. Three interim analyses were done after 62, 116, and 160 patients had completed their 4-week treatment, respectively. At the third interim analysis, the sample path crossed the upper boundary and the trial was stopped, the cure-markedly effective rates were 45% for IFCS group and 67% for IFCA group, respectively, the one-sided p-value was 0.0036, the median unbiased estimate of the odds ratio (OR for the benefit of IFCA relative to IFCS was 2.91 with 95%CI: 1.40 to 6.06. No adverse events were observed in the two groups. Conclusions Zhizhu pills

  19. Shen-Qi-Jie-Yu-Fang exerts effects on a rat model of postpartum depression by regulating inflammatory cytokines and CD4+CD25+ regulatory T cells

    Directory of Open Access Journals (Sweden)

    Li JY

    2016-04-01

    Full Text Available Jingya Li,1,* Ruizhen Zhao,1,* Xiaoli Li,1 Wenjun Sun,1 Miao Qu,1 Qisheng Tang,1 Xinke Yang,1 Shujing Zhang2 1Third Affiliated Hospital, 2School of Basic Medical Sciences, Beijing University of Chinese Medicine, Beijing, People’s Republic of China *These authors contributed equally to this work Background: Shen-Qi-Jie-Yu-Fang (SJF is composed of eight Chinese medicinal herbs. It is widely used in traditional Chinese medicine for treating postpartum depression (PPD. Previous studies have shown that SJF treats PPD through the neuroendocrine mechanism. Aim: To further investigate the effect of SJF on the immune system, including the inflammatory response system and CD4+CD25+ regulatory T (Treg cells. Materials and methods: Sprague Dawley rats were used to create an animal model of PPD by inducing hormone-simulated pregnancy followed by hormone withdrawal. After hormone withdrawal, the PPD rats were treated with SJF or fluoxetine for 1, 2, and 4 weeks. Levels of Treg cells in peripheral blood were measured by flow cytometry analysis. Serum interleukin (IL-1β and IL-6 were evaluated by enzyme-linked immunosorbent assay, and gene and protein expressions of IL-1RI, IL-6Rα, and gp130 in the hippocampus were observed by reverse-transcription polymerase chain reaction and Western blot. Results: Serum IL-1β in PPD rats increased at 2 weeks and declined from then on, while serum IL-6 increased at 1, 2, and 4 weeks. Both IL-1β and IL-6 were downregulated by SJF and fluoxetine. Changes in gene and protein expressions of IL-1RI and gp130 in PPD rats were consistent with changes in serum IL-1β, and were able to be regulated by SJF and fluoxetine. The levels of Treg cells were negatively correlated with serum IL-1β and IL-6, and were decreased in PPD rats. The levels of Treg cells were increased by SJF and fluoxetine. Conclusion: Dysfunction of proinflammatory cytokines and Tregs in different stages of PPD was attenuated by SJF and fluoxetine through

  20. 论梁启超的兴女学思想%On LIANG Qi-chao's Thought of Promotion Schools for Women

    Institute of Scientific and Technical Information of China (English)

    李斯

    2014-01-01

    In situation of the domestic trouble and foreign invasion ,Liang Qi-chao trumpeted his theory of promotion schools for women to save and rich the nation and attempted to put it into practice .He thought that schools for women are not only necessary ,but possible .It can not only train the new types of wife ,good mother and profit person ,but also can open their wisdom ,culture the new people and make contributions to save and enforcing the nation .Although there are limits in his schools for women theory ,but his theory and practice has an important historical position in the history of China's women edu-cation ,ideology and modern history .His theory not only has profound influence on the history of China's education moderniza-tion process ,but will serve as a reference for the current construction of socialism with Chinese characteristics .%在内忧外患的形势下,为挽救国家危亡并实现强国富民的理想,梁启超大力宣扬其兴女学思想并力行兴女学实践。他认为兴女学不仅是必要的,而且是可能的,不仅可培养新型贤妻、良母、生利者,而且能开民智、培养新民,为当时的救国以及强国富民做出贡献。尽管其兴女学思想存在着种种局限,但在中国的女子教育史、思想史和近代化史上仍占重要的历史地位,不仅对中国教育现代化的历史进程产生深刻影响,而且可为当前中国特色社会主义建设提供借鉴。

  1. Comparison of the Two Modeling Methonds for Qi Stagnation and Blood Stasis%两种气滞血瘀证造模方法的比较

    Institute of Scientific and Technical Information of China (English)

    王婷婷; 贾乘; 宁天一; 姜静; 程嘉艺

    2013-01-01

    To compare methods of rat modeling for Qi stagnation and blood stasis for serving the experimental of etiological factors and pathogenesis. Methods; Apply various stimulations such as noise, light, electricity, tail - clamping, icewater - bath,bondage and adrenaline injection to establish the rat mode. Adopt the pressure sensing technology of MOTO to detect hemorheology - related indicators, use the coagulation method to detect coagulation - related indicators. Results: In hemorheology, compared with the negative control group, the viscosity of whole blood of high, medium, low shear and plasma viscosity increased in the multi - factor stimulation group (P < 0. 05). The viscosity of whole blood of high shear and plasma viscosity increased in the adrenaline injection group (P <0. 05). The fibrinogen content in blood coagulation indicated significant increase in both group(P <0. 05). Conclusion; Both multi -factor stimulation and adrenaline injection can lead to blood stasis. Adrenaline injection method can be convenient and easy. Multi - factor stimulation group relatively conform the theory of etiology and pathogenesis.%目的:比较两种大鼠气滞血瘀证模型的建立方法,为研究气滞血瘀病因病机提供实验基础.方法:分别采用声光电、夹尾、束缚、冰水浴多种刺激联合应用及肾上腺素注射的方法造模.采用MOTO压力传感技术检测血液流变学相关指标,采用凝固法检测凝血四项相关指标.结果:与空白对照组相比,多因素刺激组大鼠血液流变学指标中全血高、中、低切粘度与血浆黏度均显著升高(P<0.05),肾上腺素组大鼠全血高切粘度与血浆黏度显著升高(P<0.05);两组大鼠凝血四项指标中纤维蛋白原含量均显著升高(P<0.01).结论:多因素刺激与肾上腺素注射法均能导致动物出现血瘀状态,肾上腺素注射法方便易行,多因素刺激组较符合中医病因病机理论.

  2. Qi and removing blood stasis in treating early stage cirrhosis%益气化瘀法治疗早期肝硬化

    Institute of Scientific and Technical Information of China (English)

    叶思文

    2012-01-01

      目的:就益气化瘀法治疗早期肝硬化进行探讨。方法:选取三个案例进行分析,将益气健脾,活血化瘀辨证治疗肝硬化。结果:案例1:服上方治疗3个月后病愈。随访至今未见再发。案例2诸症悉除,复查肝功能,肝胆脾彩超均属正常范围。后用上方加减研末冲服月余,以巩固疗效,随访1年未见再发。案例3诸症悉除,复查肝功能及肝胆脾彩超,其中彩超示:脾脏肿大,余项均属正常范围。后用上方加减蜜丸服药月余,病告痊愈,随访2年未见再发。结论:臌胀为临床四大疑难重症之一,其病机为肝脾肾三脏功能失调,气、血、水停于腹中,本虚标实,虚实夹杂的病理过程。%  Objective:Yiqi Huayu method treatment early time liver cirrhosis of. Methods:a total of three cases were analyzed, the Qi of the spleen, promoting blood circulation to remove blood stasis syndrome differentiation and treatment of liver cirrhosis. Results:the case of 1: served 3 months after the treatment was over. Up to now no longer hair. 2 cases are in addition to all disease, the liver function, liver spleen ultrasound within the normal range. After using the above addition and subtraction grind end each month, in order to consolidate the curative effect, follow-up of 1 years again. 3 cases are in addition to all disease, the liver function and liver spleen ultrasound, including ultrasonography indicated: enlargement of spleen, the remainder were within normal range. After taking over addition and subtraction pill month, disease to cure, follow-up of 2 years showed no recurrence. Conclusion:swelling for clinical four severe problems, its pathogenesis is spleen kidney three dirty function disorders, gas, blood, water stop in the abdomen, the superficial, inclusion of actual pathological process.

  3. Evaluation of an on-line methodology for measuring volatile organic compounds (VOC) fluxes by eddy-covariance with a PTR-TOF-Qi-MS

    Science.gov (United States)

    Loubet, Benjamin; Buysse, Pauline; Lafouge, Florence; Ciuraru, Raluca; Decuq, Céline; Zurfluh, Olivier

    2017-04-01

    Field scale flux measurements of volatile organic compounds (VOC) are essential for improving our knowledge of VOC emissions from ecosystems. Many VOCs are emitted from and deposited to ecosystems. Especially less known, are crops which represent more than 50% of French terrestrial surfaces. In this study, we evaluate a new on-line methodology for measuring VOC fluxes by Eddy Covariance with a PTR-Qi-TOF-MS. Measurements were performed at the ICOS FR-GRI site over a crop using a 30 m long high flow rate sampling line and an ultrasonic anemometer. A Labview program was specially designed for acquisition and on-line covariance calculation: Whole mass spectra ( 240000 channels) were acquired on-line at 10 Hz and stored in a temporary memory. Every 5 minutes, the spectra were mass-calibrated and normalized by the primary ion peak integral at 10 Hz. The mass spectra peaks were then retrieved from the 5-min averaged spectra by withdrawing the baseline, determining the resolution and using a multiple-peak detection algorithm. In order to optimize the peak detection algorithm for the covariance, we determined the covariances as the integrals of the peaks of the vertical-air-velocity-fluctuation weighed-averaged-spectra. In other terms, we calculate , were w is the vertical component of the air velocity, Sp is the spectra, t is time, lag is the decorrelation lag time and denotes an average. The lag time was determined as the decorrelation time between w and the primary ion (at mass 21.022) which integrates the contribution of all reactions of VOC and water with the primary ion. Our algorithm was evaluated by comparing the exchange velocity of water vapor measured by an open path absorption spectroscopy instrument and the water cluster measured with the PTRQi-TOF-MS. The influence of the algorithm parameters and lag determination is discussed. This study was supported by the ADEME-CORTEA COV3ER project (http://www6.inra.fr/cov3er).

  4. Tai Chi and Qi Gong

    Science.gov (United States)

    ... improved their functioning. For Mental Health and Cognitive Function While a range of research has suggested that ... 279. Saeed SA, Antonacci DJ, Bloch RM. Exercise, yoga, and meditation for depressive and anxiety disorders. American ...

  5. 辛弃疾的“事功派”思想及在稼轩词中的体现%Xin Qi-ji’s Utilitarianism Ethics Thought And influence on Jiaxuan Ci-poems

    Institute of Scientific and Technical Information of China (English)

    宋学达

    2013-01-01

    事功派哲学家陈亮与辛弃疾私交甚厚,其哲学思想必然会对辛弃疾产生影响,而历来对辛弃疾的研究中,似乎很少关注其思想哲学的相关问题。本文旨在论证辛弃疾的哲学思想乃是以陈亮为代表的事功派哲学一脉,并探讨事功派哲学对稼轩词艺术特质及词史地位所产生的深刻影响。%Chen Liang, the philosopher of Utilitarianism Ethics Thought, has a good relationship with Xin Qi-ji. So his philosophical thoughts certainly would have an influence on Xin Qiji. But in the past, on the study of Xin Qi-ji, we can seldom found researches concerning his thought of philosophy. This dissertation is aimed to argue that Xin's philosophical thoughts is a brunch of Chen’s Utilitarianism Ethics Thought and the latter had great influence on Jiaxuan Ci-Poems, including its artistic particularities and the status in Ci-poetry history.

  6. Clinical Research of Lamivudine Combined Liver Yin Qi Treatment of Chronic Hepatitis B Complex%拉米夫定合茵芪肝复汤治疗慢性乙型肝炎的临床研究

    Institute of Scientific and Technical Information of China (English)

    蓝青

    2013-01-01

    目的:观察拉米夫定合茵芪肝复汤治疗慢性乙型肝炎的疗效。方法在拉米夫定治疗基础上加用中药茵芪肝复汤治疗本病96例。结果患者临床症状缓解率、肝功能、HBeAg和HBV-DNA的阴转率较治疗前改善明显。结论本方对治疗慢性乙型肝炎疗效确切,值得临床使用。%Objective: To observe the curative Effect of lamivudine combined Yin Qi liver recovery decoction in the treatment of chronic hepatitis B. Methods: in the lamivudine treatment combined with traditionallChinese medicine Yin Qi of liver in 96 cases of the disease complex soup. Results: the clinicallsymptoms of patients in remission rate, liver function, HBeAg and HBV-DNA negative conversion rate was significantly improved than before treatment. Conclusion: the curative Effect on treatment of chronic hepatitis B is exact, it is worthy of clinicalluse.

  7. Research on Month Rhythm Change of Plasma Metabolic Markers of Rat with Wei Qi Deficiency%卫气虚模型大鼠血浆代谢标志物月节律变化的研究

    Institute of Scientific and Technical Information of China (English)

    李博林; 王亚利; 张明泉; 王鑫国; 贾琳; 闫翠环; 曹文利; 师旭亮

    2016-01-01

    目的:运用代谢组学方法研究卫气虚证月周期性变化的物质基础,寻找其潜在标志物,为卫气虚证实质研究提供新的途径。方法以秋分日所在的农历月,确定月初(农历八月初一)、月中(八月十五)及月末(八月三十)3次实验的取材时间。取材日前2周将20只大鼠随机分为正常组与模型组,每组10只。模型组采用疲劳联合寒热交替法制备卫气虚模型,正常组常规喂养。3次实验均在其相应取材日正午12:00断头取血,采用高效液相色谱-质谱联用仪检测血浆代谢物,利用偏最小二乘法对数据进行统计分析,组间进行比较,探索卫气虚证差异性代谢标志物,进而推测寻找卫气虚证月周期变化的潜在标志物。结果油酸酰胺、磷脂酰甘油、皮质醇、脯氨酸、富马酸二甲酯、二十碳五烯酸6种差异代谢物可能为月初卫气虚证潜在证候标志物;1-磷酸鞘氨醇、苹果酸、皮质醇、油酸酰胺、肉毒碱、二十碳五烯酸、富马酸二甲酯7种差异代谢物可能为月中卫气虚证潜在证候标志物;胆固醇乙酸酯、苏氨酸、皮质醇、富马酸二甲酯、油酸酰胺、二十碳五烯酸、焦谷氨酸7种差异代谢物可能为月末卫气虚证潜在证候标志物。结论卫气虚证月周期性变化可能受油酸酰胺、皮质醇、二十碳五烯酸、富马酸二甲酯影响,其周期性变化可能与能量代谢密切相关,同时还伴随着细胞、激素及神经调节。%Objective To use metabonomics method to study the change of the basic materials of month rhythm of wei qi deficiency syndrome; To find the potential markers so as to provides a new way for the essence of the wei qi deficiency syndrome research.Methods Based on the autumnal equinox in lunar calendar month, the beginning of a month (the first day of lunar August), the middle of a month (the 15th day of lunar August), and the end of a

  8. Contribution of Fragmentary Argumentation of Qi Min Yao Shu to the Construction of Accounting Culture%《齐民要术・杂说》对会计文化建设的贡献

    Institute of Scientific and Technical Information of China (English)

    2013-01-01

      贾思勰《齐民要术・杂说》对会计文化的贡献很多,包括提高利用固定资产效率、预测决策、实地考察、区别对待、调节市场、提高效益等思想,其对中国会计文化建设的核心贡献就在于合理有效运用“资产”。%Qi Min Yao Shu written by Jia Sixie has made great contributions to accounting culture , including:improving the efficiency of using fixed assets , decision predicting, taking field trips, dealing with different lands in different ways, adjusting the market, improving effectiveness and so on.The contribution of Qi Min Yao Shu to the construction of Chinese accounting culture lies in that it teaches a lesson of how to make use of "assets"reasonably and effectively.

  9. 新邵湘语的补语标记助词“倒”和“起”%On the Complement -Marking Auxiliary Words Dao and Qi in Xinshao Dialect

    Institute of Scientific and Technical Information of China (English)

    朱玲君

    2012-01-01

    新邵湘语的补语标记助词“倒”和“起”都可连接述语和情状补语,“倒”使用频率最高,“起”最低。它们都是从结果补语语法化而来。比较发现,当补语是光杆性质形容词或单音节词时,由补语标记助词“得”引导。%The complement- marking auxiliary words Dao and Qi in Xinshao dialect in Hunan can connect the predicate to the state complement or degree complement. As to the frequency of use, Dao is the highest while Qi is the lowest. Both of them were deprived from the grammaticalization of result complements. Through compari- son, it is found that when the complement is just a qualitative adjective or a monosyllable adjective, then it must be connected by another complement -marking auxiliary word De to the predicate.

  10. Study on the relationship between Stagnation of Liver-QI and pathogenesis of recurrent depressive disorder%复发性抑郁障碍发病机制及与肝郁关系探讨

    Institute of Scientific and Technical Information of China (English)

    李涛; 赵阳; 汪卫东; 洪兰; 林颖娜; 王芳; 闫雪

    2012-01-01

    Pathogeny of first depression is different with its recurrence.Past studies on depressive disorder suggest that its pathological loop may adjust, End. Present dynamic changes during long-term disease course. However, we still could not lully un- destand its nerval changes of biochemistry structure during first onset period, paracmasis, and recurrence, stagnation of liver-QI is relation with psychological stress. Depression relapse was constructed by stress to imitate the form of stagnation of liver-QI.%抑郁症初发与复发的机理有所不同,以往研究提示抑郁症的病理环路在长期病程中可能会有所调试,呈现动态改变,但目前无法清楚了解其初次发作期、缓解期及复发期的神经生化结构改变情况.中医肝郁证与心理应激有关,通过应激诱发抑郁状态可以很好地模拟情志异常引发肝郁证的过程.

  11. Volatile organic compounds sources and sinks in a wheat canopy. Analysis based on combined eddy-covariance fluxes, in-canopy profiles and chamber measurements with a PTR-TOF-Qi-MS

    Science.gov (United States)

    Loubet, Benjamin; Gonzaga, Lais; Buysse, Pauline; Ciuraru, Raluca; Lafouge, Florence; Decuq, Céline; Zurfluh, Olivier; Fortineau, Alain; Fanucci, Olivier; Sarda-Esteve, Roland; Zannoni, Nora; Truong, Francois; Boissard, Christophe; Gros, Valérie

    2017-04-01

    Volatile organic compounds (VOC) are essential drivers of atmospheric chemistry. Many VOCs are emitted from and deposited to ecosystems. While forests and grasslands have already been substantially studied, exchanges of VOCs with crops are less known, although these ecosystems represent more than 50% of the surface in France. In this study, we analyze sources and sinks of VOCs in a wheat field (at the ICOS FR-GRI site near Paris) at anthesis based on measurements of fluxes, concentration profiles and branch chambers. The VOCs were measured using a PTR-TOF-Qi-MS (where Qi stands for Quad Ion guide). Air was successively sampled through lines located at different heights within and above the canopy, of which one was used for Eddy Covariance and located near a sonic anemometer. Additional measurements included the standard ICOS meteorological data as well as leaf area index profiles and photosynthesis curves at several heights in the canopy. We report fluxes and profiles for more than 500 VOCs. The deposition velocities of depositing compounds are compared to the maximum exchange velocity and the ozone deposition velocity. The sources and sinks location and magnitude are evaluated by inverse Lagrangian modelling assuming no reaction and simple reaction schemes in the canopy. The sources and sinks of VOC in the canopy are interpreted in terms crop phenology and the potential for reaction with ozone and NOx is evaluated. This study takes place in the ADEME CORTEA COV3ER French project (http://www6.inra.fr/cov3er).

  12. The Comparative Study of Qi -Liang Dynasties Poetry and Folk Songs in Southern Dynasty%齐梁宫体诗与南朝民歌比较研究

    Institute of Scientific and Technical Information of China (English)

    汪毓梓

    2015-01-01

    Qi-Liang Dynasties Poetry and folk songs in Southern Dynasty are produced in roughly the same time , and it has certain feasibility and research value for the comparison of the different literary genres under the same back -ground .This paper compares and demonstrates similarities and differences between Qi -Liang Dynasties Poetry form poetry and folk songs in southern dynasty through concrete analysis of such aspects as the generation and development conditions , the subject matter and content , the form, the style and the description methods and so on .%齐梁宫体诗与南朝民歌产生于大致相同的时代,对产生于相似背景下的不同文学体裁进行比较,有一定的可行性和研究价值。本文通过具体分析,主要对齐梁宫体诗与南朝民歌在产生与发展的条件、题材内容、表现形式、风格、描写手法等方面的异同进行比较研究与论证。

  13. Theory of protecting stomach qi in Treatise on Cold Pathogenic Diseases and its clinical significance%论《伤寒论》的保胃气思想及其临床意义

    Institute of Scientific and Technical Information of China (English)

    郝迎旭

    2015-01-01

    The theory of protecting stomach qi throughout Treatise on Cold Pathogenic Diseases- the original book of Chinese medicine syndrome differentiation, in which the function of spleen and stomach are emphasized in morbidity and treatment based on syndrome differentiation. Therefore, the theory of protecting spleen and stomach can be seen throughout syndrome differentiation according to six channel and miscellaneous diseases treatment according to syndrome differentiation in Treatise on Cold Pathogenic Diseases. This article analyses the theory in terms of 10 aspects, that is, emphasizing spleen and stomach according to serve as a link between past and future, six channel disease focus on spleen and stomach, spleen and stomach are the junction during six channel transmission, no invading stomach qi in treatment, attaching importance to spleen and stomach in prescription, regulating the cold, heat, deficiency and excessive of spleen and stomach, treating contraindication based on protection of spleen and stomach, taking care of spleen and stomach when boiling and taking medicine, good or ill luck prognosis due to stomach qi, adjusting after revovery in order to cultivate acquired foundation.%中医辨证论治之鼻祖的《伤寒论》始终贯穿着保胃气的思想,十分重视脾胃在人体发病和辨证论治中的作用,顾护脾胃的思想和保胃气之秘旨贯穿于《伤寒论》六经辨证论治体系和杂病辨证论治体系通篇。从承前启后重视脾胃,六经发病重在脾胃,六经传变脾胃为枢,治疗原则无犯胃气,立法处方法重脾胃,调理脾胃寒热虚实,提出治禁源于护胃,煎服调护顾护脾胃,预后吉凶胃气为本,病瘥调理继培后天等10个方面进行论述。

  14. Analysis on the Treatment of Non-alcoholic Fatty Liver of Qi Stagnation due to Spleen Deficiency%脾虚气滞型非酒精性脂肪肝的治疗分析

    Institute of Scientific and Technical Information of China (English)

    张辉凯; 孟祥林; 李海雷

    2016-01-01

    Objective To analyze the therapeutic effect of Zhishi Xiaopi pill in the treatment of non-alcoholic fatty liver of qi stagnation due to spleen deficiency .Methods Clinical data of 110 cases of patients with non-alcoholic fatty liver of qi stagnation due to spleen deficiency from March 2014 to March 2015 was retrospectively selected .According to the treatment program , the control group of 50 cases used Zhibituo tablets, and the study group of 60 cases used Zhishi Xiaopi pill .The data were compared and analyzed .Results The TC, TG and ALT indicators of the study group were better than those of the control group , the total effective rate of the study group was 96.67% which was higher than 44.00%of the control group , and the difference was statistically significant ( P<0.05) .Conclusion Zhishi Xiaopi pill in the treatment of non-alcoholic fatty liver of qi stagnation due to spleen deficiency has significant effect .%目的:分析脾虚气滞型非酒精性脂肪肝采用枳实消痞丸治疗效果。方法选择2014年3月—2015年3月本院110例脾虚气滞型非酒精性脂肪肝患者临床资料,根据治疗时所用方案分组,对照组50例行脂必妥片治疗,研究组60例行枳实消痞丸治疗,对资料进行对比和分析。结果研究组TC、TG、ALT指标优于对照组,研究组总有效率96.67%高于对照组44.00%,两组均具统计学意义(P<0.05)。结论脾虚气滞型非酒精性脂肪肝采用枳实消痞丸治疗效果显著。

  15. Clinical Observation of Qi and Yin Deficiency Diabetes of Traditional Chinese Medical Dietary Therapeutic Schedule%气阴两虚型消渴病中医饮食治疗方案的临床观察

    Institute of Scientific and Technical Information of China (English)

    唐铁梅

    2015-01-01

    目的 研究气阴两虚型消渴病患者制定中医饮食治疗方法 的临床效果.方法 选择120例气阴两虚型消渴病患者分为两组,对照组实施常规饮食方案,观察组实施中医饮食干预,比较两组患者的血糖、糖化血红蛋白以及生存质量变化.结果 观察组空腹血糖,餐后2 h血糖、糖化血红蛋白以及生存质量优于对照组,P<0.05,差异具有统计学意义.结论 气阴两虚型消渴病患者通过中医饮食治疗方案能够有效的降低患者的空腹血糖、餐后血糖以及糖化血红蛋白水平,提升患者的治疗效果,改善糖尿病患者的生存质量.%Objective Clinical observation of qi and yin deficiency diabetes of traditional Chinese medical dietary therapeutic schedule. Methods Selected 120 cases of type of deficiency of both qi and Yin of diabetes patients who had diagnosis and treatment, were divided into two groups, the control group underwent routine diet plan, implementation of TCM diet intervention of patients in the observation group, compared two groups of patients with blood glucose, glycosylated hemoglobin and quality of life changes.Results The observation group, the fasting blood glucose, postprandial 2 hours blood glucose, glycosylated hemoglobin, and quality of life were better than the control group,P<0.05, was difference had statistically significance.Conclusion Patients with deficiency of both qi and yin type diabetes by TCM diet therapy can effectively reduce patients with fasting blood glucose, postprandial blood glucose and glycated hemoglobin levels, improve therapeutic effect of patients and the quality of life.

  16. Efficacy Observation on Comprehensive Therapy for Cervical Spondylotic Radiculopathy of Qi Stagnation and Blood Stasis Type%综合治疗气滞血瘀型神经根型颈椎病疗效观察

    Institute of Scientific and Technical Information of China (English)

    蒋芳华; 陈进城; 陈水金; 陈少清; 王诗忠

    2014-01-01

    Objective:To observe the efficacy of comprehensive therapy for cervical spondylotic radiculopathy of qi stagnation and blood stasis type. Methods:68 cases of patients with cervical spondylotic radiculopathy of qi stagnation and blood stasis type were randomly divided into treatment group (34 cases) and control group (34 cases), the treatment group treated by comprehensive therapy which included cervical immobilization, mas-sage, acupuncture, Chinese herbs and physiotherapy, while control group only by acupuncture and massage, then evaluated the efficacy after 2 course of treatment. Results:The total effective rate of treatment group was higher than that of control group (P<0.05), the VAS score was lower than that of control group (P<0.05), and the maximum strength of right and left lateral flexion, anteflexion, extension were all better than those of control group (P<0.05). Conclusion:Comprehensive therapy has significant curative effect on cervical spondylotic radiculopathy of qi stagnation and blood stasis type, deserves clinical promotion and application.%目的:观察综合治疗气滞血瘀型神经根型颈椎病的疗效。方法:将68例气滞血瘀型神经根型颈椎病患者随机分为治疗组(34例)和对照组(34例),治疗组采用颈部制动、推拿、针灸、中药、物理治疗等综合治疗,对照组则仅给予针灸、推拿治疗,2个疗程后评定疗效。结果:治疗组总有效率高于对照组(P<0.05),VAS评分低于对照组(P<0.05),颈椎左右侧屈、前屈和后伸最大肌力均优于对照组(P<0.05)。结论:综合治疗气滞血瘀型神经根型颈椎病疗效显著,值得临床推广应用。

  17. 健脾行气法治疗功能性消化不良临床观察%Clinical Observation of Using Spleen Invigorating and Qi Promoting Method to Treat Functional Dyspepsia

    Institute of Scientific and Technical Information of China (English)

    张庆; 梁超

    2011-01-01

    Objective: To observe the clinical curative effect using spleen invorating and Promoting Qi method to threat functional dyspepsia, and approach the superiority in the Traditional Chinese Medicine to treat chronic appetite systemic disease.Methods: To utilize the method of invigorating spleen and promoting Qi to differentiate symptoms and signs and add or to decrease according of clinical symptom to treat thirty examples of the type of splenic asthenia and gas-sluggish of functional dyspepsia, and thirty examples of control group. The treatment group was given prescription according to the method of invigorating spleen and Qi promoting to add or to decrease; the control group was treated by means of domperidone. The average course of treatment was four weeks. Contrasting the index of two sets, such as the total effective rate, total accumulated points of symptom, the improve of major clinical symptom and so on, as well as to make out the judgement. Results: The total effective rate of curity group was 90%, and the control group was 67.9%, there was significant difference between the two groups, P<0. 05,to hint that the total curative effect of curity group surpass the control group to use the method of invigorate spleen and invigorating spleen and promoting Qi to cure the type of splenic asthenia and gas sluggish of functional cyspepsia. Conclusion: The curative effect is indeed that according to the method of respiration technique and respiration technique to treat the type of splenic asthenia and gas sluggish of functional dyspepsia, and it also is one of effective method to treat functional dyspepsia.%目的:观察健脾行气法治疗脾虚气滞型功能性消化不良的临床疗效,并探讨中医药在治疗慢性脾胃系统疾病中的优势.方法:将确诊为脾虚气滞型功能性消化不良患者58例随机分为治疗组30例,对照组28例.治疗组予以根据健脾行气法拟定的运脾行气汤加减治疗;对照组予以多

  18. 滋肾疏肝法治疗围绝经期妇女不寐48例的临床观察%Observe 80 Cases Insomnia of Menopausal Women by Nourishing Yin and Regulating Liver Qi

    Institute of Scientific and Technical Information of China (English)

    闫凤乐; 周岳君

    2013-01-01

    Objective] To discuss the pathogenesis of the menopausal women with insomnia and observe the clinical curative effect of the method which is nourishing Yin and regulating liver Qi.[Method] Col ect 80 patients in the clinic which were randomly divided into two groups.48 cases in the treating group were treated by the method of nourishing Yin and regulating liver Qi ,and 32 patients in the control group were given 1mg estazolam .The period of treatment lasted for 1 course.To observe the curative effects and the total effective rates of the two groups. [Results] After the treatment, the total effective rate was 91.67%in treatment group by nourishing Yin and regulating liver Qi. The total effective rate was 90.62%in the control groups, there no statistical significance etween them. For the treatment to the accompanying symptoms of perimenopausal, hot flash and sweating were improved significantly better than the control group; improving the night dream frequency multiple, long-term constipation, sad to cry and other symptoms of the treatment group was significantly better than the control group. [Conclusion]It is indicated that the method of nourishing Yin and regulating liver Qi has a significant therapeutic effect on insomnia of the menopausal women .%  [目的]探讨围绝经期妇女不寐的中医病机,观察滋肾疏肝法治疗的临床疗效。[方法]收集门诊围绝经期妇女不寐病患80例,随机分为中药治疗组(简称治疗组)和西药对照组(简称对照组),治疗组给予滋阴疏肝法治疗,对照组给予1mg舒乐安定治疗,4周为1个疗程。1个疗程结束后观察两组总有效率、临床症状及伴随症状的改善情况。[结果]滋阴疏肝法治疗围绝经期妇女不寐的总有效率为91.67%,舒乐安定的总有效率为90.62%,差异无统计学意义(P>0.05)。在治疗伴随症状方面,潮热症状改善治疗组优于对照组,差异有显著统计学意义(P<0.01),夜梦频多、长期便

  19. 脾气虚证大鼠回肠组织蛋白质差异性表达的实验研究%Experimental Study on the lieum Tissue Proteins Differentially Expressed in Pi-qi Deficiency Syndrome Rats

    Institute of Scientific and Technical Information of China (English)

    吕凌; 贾连群; 马巍; 宋雪娇; 崔永霞; 王彩霞

    2012-01-01

    Objective To identify the ileum tissue proteins differentially expressed in Pi-qi deficiency syndrome rats using proteomic approach. Methods Thirty-seven rats were randomly divided into 3 groups, i. e., the normal control group (Group 1), the Pi-qi deficiency syndrome model group (Group 2), and the reserpine group (Group 3). The Pi-qi deficiency syndrome model was established using excessive exerting combined with irregu-. lar diet, and peritoneally injecting Reserpine Injection (1 mg/mL) respectively. The ileum tissues were separated after identified fuzzy method. The differentially expressed proteins were separated with two dimensional electro-phoresis (2-DE), analyzed by Mass Spectrometry, and identified by MASCOT Software. Results Three proteins were differentially expressed in Group 2 and nine proteins were differentially expressed in Group 3 (P < 0. 05). Conclusion Pi-qi deficiency syndrome was closely related with decreased expression of albumin as well as increased expressions of trypsin and glucose-regulated protein 78.%目的 采用蛋白质组学技术研究脾气虚证大鼠回肠组织蛋白的差异性表达.方法 37只大鼠随机分成3组,即正常对照组、脾气虚证模型组和利血平组.分别采用劳倦过度结合饮食不节和利血平注射液(1 mg/mL)腹腔注射的方法建立脾气虚证动物模型,通过模糊数学方法鉴定后分离回肠组织,后采用双向电泳法分离差异表达的蛋白,凝胶银染后经选点、酶切和质谱分析,用MASCOT软件在蛋白质数据库中搜索肽质量指纹谱数据并确定蛋白质.结果 脾气虚证模型组回肠组织蛋白质图谱中有3个蛋白点表达异常(P<0.05),利血平组回肠组织蛋白质图谱中有9个蛋白点表达异常(P<0.05).结论 脾气虚证的发生与白蛋白表达下调、胰蛋白酶和葡萄糖调节蛋白78表达上调有密切关系.

  20. 气虚血瘀型Corti器毛细胞损伤动物模型的建立%Establishing hair cell damage model in the animal Corti organ with Qi deficiency and blood stasis

    Institute of Scientific and Technical Information of China (English)

    彭桂原; 李松键; 杨黎; 杨朝杰; 谭串

    2016-01-01

    背景:随着中医药对耳鸣耳聋的疗效越来越受到重视,但对其机制尚缺乏系统深入的研究,利用动物模型进行中医药治疗耳鸣耳聋的机制探索是非常有意义的研究方向。  目的:建立一种气虚血瘀证型的Corti器毛细胞损伤动物(豚鼠)模型并评价其效果。  方法:12只成年豚鼠按随机数字表法分为正常对照组和造模组。造模组首先采用改良耗气破气加饥饱失常法处理15 d进行气虚造模,之后以光化学反应法复制血瘀Corti器毛细胞损伤模型;正常对照组不干预。造模后检测两组豚鼠血清的D-木糖浓度,行耳声发射DPOAE测试,并观察光镜下耳蜗组织形态。  结果与结论:①与正常对照组相比,造模组血清D-木糖浓度较低(P OBJECTIVE:To establish hair cel damage model in the Corti organ with Qi deficiency and blood stasis in guinea pigs, and to assess its effects. METHODS:Twelve adult guinea pigs were randomly divided into normal control and model groups by random number table method. Guinea pigs in the model group were firstly treated with the modified relieving stagnated Qi and abnormal starvation for 15 days to model Qi deficiency, and then stimulated hair cel damage with blood stasis by photochemical induction. The controls received no intervention. Subsequently, the detection of serum D-xylose content and DPOAE test were performed, and the cochlea morphology was observed under light microscope. RESULTS AND CONCLUSION:(1) The serum D-xylose content in the model group was significantly lower than that in the normal control group (P<0.01). (2) DPOAE test revealed that the amplitudes of 1 560 and 3 125 Hz in the model group were lower than those in the normal control group and before modeling (P<0.01). (3) In the model group, hemangiectasis and microthrombosis appeared in the spiral ligament, microvascular basement membrane and modiolus capil aries, and stria vascularis

  1. 沉重的祭品——曹七巧悲剧内涵再探%A Somber Sacrifice —— A Review of the Implication of Cao Qi-qiao' Tragedy

    Institute of Scientific and Technical Information of China (English)

    陈俐

    2011-01-01

    从社会体制、性别文化及人的恶魔性因素对曹七巧这一让人可怖又深感可怜的“变态人格”的悲剧内涵进行探析,进而揭示传统封建宗法制度下女性在男权社会中的生存状态,唤取人们对女性命运的关注和思考。%Through re-studying the social system, the culture of gender and the vicious human nature, this paper is in- tended to reveal the implication of Cao Qi-qiao's horrible,wretched and perverted personality as well as the living condi- tions of the women in a patriarchal society within the traditional feudal patriarchal system and call the readers to focus on and think about the women's destiny.

  2. 疏肝补肾法对疲劳大鼠的学习和记忆力之影响%Effects of Regulating Liver Qi and Tonifying Kidney on Learning and Memory of Fatigue Rats

    Institute of Scientific and Technical Information of China (English)

    马佳美; 李峰; 宋月晗; 范新六; 王丽晔; 刘燕; 刘晓兰

    2011-01-01

    目的:探讨疏肝补肾法对疲劳大鼠学习和记忆力及对海马CA1区神经颗粒素(Neurogranin,Ng)的mRNA表达变化的影响.方法:成年雄性Spargue-Dawley大鼠36只,随机分为模型组(MG)、对照组(CG)、和疏肝补肾组(LK).采用复合模型:运动疲劳模型与睡眠剥夺法造疲劳大鼠模型.运用Y迷宫进行学习和记忆力的测试.以Real-timePCR技术分析海马CA1区神经颗粒素的mRNA表达.结果:Y迷宫实验显示用药后大鼠的学习和记忆能力优于模型组,而疏肝补肾组大鼠在正确反应率、错误反应次数、达标所需训练次数和总反应时间皆与模型组有差异(分别为P<0.01、P<0.01、P<0.05和P<0.05),其NgmRNA在海马CA1区的表达也显着高于模型组(P<0.01).结论:复合模型会造成大鼠学习和记忆能力受损.疏肝补肾法能显着影响疲劳大鼠的学习记忆能力及海马CA1区Ng的mRNA表达.%Objective: To study the effects of regulating liver Qi and tonifying kidney on learning and memory of fatigue rats, and on the mRNA level of neurogranin in the CA1 region of rats hippocampus. Methods: Thirty-six male adult Spargue-Dawley rats were randomly separate into three groups, model group (MG, n=12), control group (CG, n=12) and regulate liver Qi and tonify kidney group (LK, n=12). By using combined models: exercise fatigue model and sleep deprivation as our fatigue model. Y maze has been used to test the memory and learning of rats and the mRNA level of Neurogranin was tested by using Real-time PCR. Results: The results from Y maze test showed that the ability of memory and leaning of rats that took regulating liver Qi and tonifying kidney formula performed better than model group, as the results of correct response rate, times of error reaction, standard required training times and total reaction time were all significant between LK group and model group (P<0.01, P<0.01, P<0.05 and P<0.05). The neurogranin mRNA level in CA1 region

  3. 自拟眩晕定方治疗气虚血瘀型眩晕30例疗效观察%Self-Treatment of vertigo Qi and Blood given 30 cases of vertigo

    Institute of Scientific and Technical Information of China (English)

    田丽君; 王净净; 肖磊

    2011-01-01

    目的:观察自拟眩晕定方治疗气虚血瘀型眩晕的临床疗效.方法:将57例患者随机分为两组,其中对照组27例,给予盐酸氟桂利嗪治疗;治疗组30例,给予自拟眩晕定方治疗,两组均以7 d为1个疗程,治疗2个疗程后统计疗效.结果:总有效率治疗组为96.7%,对照组为70.4%,治疗组优于对照组,差异有统计学意义(P<0.05).结论:自拟眩晕定方治疗气虚血瘀型眩晕有较好疗效.%Objective: To observe the self vertigo set Qi and Blood Treatment of the clinical efficacy of vertigo. Methods: 57 patients were randomly divided into two groups, one control group of 27 patients received treatment flunarizine hydrochloride; treatment group, 30 patients received treatment from the party determined to be vertigo, two groups were 7 d as a course of treatment, Statistical treatment effect after 2 courses. Results: The total effective rate of treatment group was 96.7%, 70.4% of the control group, the treatment group than the control group, the difference was statistically significant (P<0.05). Conclusion: Treatment of self vertigo set Qi and Blood vertigo has a good effect.

  4. Northern Qi King Leling’ s and His Spouse’ s Epitaphs and Prince Bainian’ s Death%北齊樂陵王及王妃斛律氏墓誌與百年太子命案本末

    Institute of Scientific and Technical Information of China (English)

    辛德勇

    2012-01-01

    Gao Bainian (高百年) ,known as Prince Bainian (百年太子) ,was the son of Emperor Gao Yan (高演) in the Northern Qi period. When Emperor Gao Yan was dying , he succeeded his throne to his brother Gao Zhan (高湛) . Prince Bainian was dismissed as King Leling (樂陵王) by his uncle Gao Zhan. According to History of the Northern Dvnasties (《北史》) , Prince Bainian was murdered by Gao Zhan in June at the third year of Heqing (河清) , which was widely regarded as a reliable record. During the early years of Republic of China, Gao Baini-an’ s and his spouse Hulü’ s (斛律氏) epitaphs, which were inscribed on stone tab-lets within their tombs, was discovered in Hebei Province. In the epitaphs, however, the time of Prince Bainian’ s death is different from that in History of the Northern Dy-nasties. Scholars, such as Luo Zhenyu (羅振玉) ,began to reconsider Prince Baini-an’ s death based on the two epitaphs. The paper is attempting to analyze the homicide case from a broader point of view. When Emperor Gao Zhan was threatened by a number of unusual celestial phe-nomena, he believed that the only way to protect his throne as well as his life was to kill Prince Bainian. In Gao Zhan’ s time, it was accepted that magic arts of yinyang (陰陽) was a decisive force in one’ s life. The epitaphs disguised the truth to cover up for the Emperor. Given the social and cultural background in Northern Qi, the time of Prince Bainian’ s death should not conform to the epitaphs.

  5. 王琦教授从湿热体质论治痤疮的理论探析%Theoretical investigation of professer WANG Qi treating acne based on the damp-heat constitution

    Institute of Scientific and Technical Information of China (English)

    俞若熙; 倪诚; 王琦

    2012-01-01

    Based on the theory of "constitution can be divided","body disease-related"and"physical adjustable" of Professor WANG Qi, the pathogenesis of acne and damp-heat constitution closely related, the clinical manifestations of acne accord with damp-heat constitution features ,the pathogenesis of acne based on hot-humid constitution and manifested by poison,stasis and phlegm together, and claims the point of view that treating acne should be from the damp-heat constitution. This paper based on the clinical characteristics, etiloogy and pathogenesis of acne, take the clinical case of professor WANG Qi in treating acne by clearing heat and exerting dampness intervention for damp-heat constitution type, for example, to show the superiority of treating acne based on body constitution and the guiding significance to clinical.%基于王琦教授“体质可分”、“体病相关”、“体质可调”的体质理论,痤疮的发病与湿热体质密切相关,痤疮的临床表现符合湿热体质特征,痤疮的病机要点以湿热体质为本,毒瘀痰结为标,主张从湿热体质论治痤疮.文章在分析痤疮的临床特征、发病的病因病机与湿热体质相关性的基础上,佐以王琦教授从清热利湿干预湿热体质论治痤疮的病例加以说明,从而显示出辨体论治在治疗痤疮中的临床优越性和指导意义.

  6. Effect of Chinese Medical Prescription of Strengthening Spleen and Replenishing Qi on Neurogranin and LTP of Hypothyroidism Rats Hippocampus CA1 Region%益气健脾方对甲状腺功能减退大鼠海马CA1区神经颗粒素及LTP的影响

    Institute of Scientific and Technical Information of China (English)

    郭建中; 韩颖萍

    2016-01-01

    Objective:To observe the effects of Chinese medical prescription of strengthening spleen and replenishing Qi on neurogranin and LTP of hypothyroidism rats hippocampus CA1 region.Method:To give SPF level adult rats antithyroid drugs (ATD) and produce hypothyroidism models.Drug administration:Tapazole suspension 2.7 mg · kg-1 per day for 45 days.On day 46,randomly group rats into 6 groups,the control group,the model group,the levothyroxine sodium tablets group,the small dosage strengthening spleen and replenishing Qi prescription group,the large dosage strengthening spleen and replenishing Qi prescription group,strengthening spleen and replenishing Qi prescription and thyroxine combination group.Given the control group and model group 10 mL · kg-1 deionized water every day,and given other groups different drugs,once per day for 15 days,and observed the effects on neurogranin and LTP of hypothyroidism rats hippocampus CA1 region.Results:The protein expression level of hypothyroidism rats CA1 region of every group was dramatically improved,and there was a significant difference between that of the model group (P < 0.01),meanwhile,there was no significant difference among the levothyroxine sodium tablets group,the large dosage strengthening spleen and replenishing Qi prescription group,and strengthening spleen and replenishing Qi prescription and the thyroxine combination group (P > 0.05);the effects of the levothyroxine sodium tablets group,the large dosage strengthening spleen and replenishing Qi prescription group,and strengthening spleen and replenishing Qi prescription and the thyroxine combination group was better than that of the small dosage strengthening spleen and replenishing Qi prescription group,there was a significant difference(P < 0.01).After the treatment of levothyroxine sodium tablets and strengthening spleen and replenishing Qi prescription,the LTP of pothyroidism rats was observably higher than that of the model group (P < 0.01),but LTP of

  7. Effects analyzing of reinforcing the Primordial Qi in the process of prevention and treatment to patients with AIDS-related diarrhea%试析培补元气在艾滋病相关性腹泻防治中的作用

    Institute of Scientific and Technical Information of China (English)

    张亚萍; 梁健; 邓鑫; 李永亮

    2011-01-01

    艾滋病相关性腹泻的发生主要责之于脾虚湿盛,与肺脾肾等脏腑功能失调密切相关.元气是人体生命活动的原动力,具有推动和调节人体脏腑生理活动之功;同时,元气也是正气的重要组成部分,对维持人体的免疫功能有着重要的作用.脾胃水谷精气对元气有滋养之功,两者相互为用,密切相关.从培补元气人手防治艾滋病相关性腹泻,是中医学“治病求本”思想的体现.培补元气,不仅对推动和激发艾滋病患者脏腑功能活动、改善机体虚弱的状态、提高其免疫功能有重要作用,而且对减轻患者腹泻的症状、减少腹泻发生的次数、提高患者的生活质量都有积极的影响.%The main cause of the onset of AIDS-related diarrhea is damp abundance due to spleen asthenia syndrome and the function situation of lung, spleen, and kidney has a lot to do with it. Primordial Qi is the primitive active power of human actions and can promote and regulate the physiological activities of human being. Meanwhile, Primordial Qi which is the major components of vital Qi has a lot to do with the maintenance of immune function of human being. The nutrients grown and transformed in the spleen and stomach moisten the vital Qi. These two has a close relationship and react to each other. To prevent and treat AIDS-related diarrhea by cultivating and promote Primordial Qi embodies the thoughts of TCM which goes treating a disease by removing its cause. Reinforcing the Primordial Qi can not only stimulate the functional activities of Zang-Fu, better the general condition of body and improve the immune function of the patients with AIDS, but also has positive effects in eliminating the symptoms of diarrhea, decreasing the frequency of the occurrence of diarrhea and improving the quality of life.

  8. 柴疏四君汤对肝郁、脾虚和肝郁脾虚模型大鼠性腺轴的影响%Effect of Chaishu Sijun Decoction on the Gonad Axis of Gan-qi Stagnation, Pi Deficiency, and Gan-qi Stagnation Pi Deficiency Model Rats

    Institute of Scientific and Technical Information of China (English)

    李聪; 谢鸣; 赵荣华; 王帮众; 么元超

    2014-01-01

    Objective To observe changes of gonad functions of Gan-qi stagnation (GS),Pi deficiency (PD),Gan-qi stagnation Pi deficiency (GSPD) model rats,and the effect of Chaishu Sijun Decoction (CSD) on them.Methods Rats were randomly divided into 7 groups according to romdom digit table,i.e.,the normal control group,the GS model group,the GS medication group,the PD model group,the PD medication group,the GSPD model group,and the GSPD medication group,10 in each group.Rats in the GS model group,the PD model group,and the GSPD model group were treated with chronic restraint,improper diet + excessive fatigue,chronic restraint + improper diet + excessive fatigue.The model was established for 4 successive weeks.Starting from the 15th day of modeling,CSD at the daily dose of 3.57 g/kg was given by gastrogavage to them for 14 successive days.Equal volume of distilled water was given by gastrogavage to rats in each model group and the normal control group for 14 successive days.The blood contents of gonadotrophin releasing hormone (GnRH),follicular stimulating hormone (FSH),luteinizing hormone (LH),estradiol (E2),and testosterone (T) were detected in rats of each group.Results Compared with the normal control group,there was statistical difference in GnRH,T,E2,and FSH in the GS,PD,and GSPD model groups (P <0.05,P <0.01).The content of LH was elevated in the GS model group (P <0.05) and declined in the GSPD model group (P <0.01).Compared with the GS model group,the contents of FSH,LH,and T decreased and E2 increased in the PD model group (all P <0.05) ; the contents of FSH and LH also declined in the GSPD model group (P<0.05).Compared with the PD model group,the T content increased and FSH decreased in the GSPD model group (all P <0.05).Compared with each corresponding model group,the FSH content decreased (P <0.01) and LH increased in the GS medication group; the T content increased,E2 and LH decreased (P <0.05,P <0.01) in the PD medication group; the T content

  9. Clinical Study on Chronic Gastritis Treated by Methods of Replenishing qi,Activating Spleen and Eliminating Blood Stasis%益气健脾化瘀法治疗慢性胃炎临床研究

    Institute of Scientific and Technical Information of China (English)

    刘俊峰; 何高潮

    2012-01-01

    目的:探讨益气健脾化瘀法治疗慢性胃炎的疗效.方法:将90例患者随机分为两组.治疗组60例采用益气健脾化瘀法治疗,药用丹参、檀香、砂仁、党参、白术、茯苓、枳壳、厚朴、黄连、吴茱萸、百合、乌药、甘草治疗.对照组30例采用法莫替丁片合果胶铋胶囊治疗.结果:治疗组痊愈28例,显效12例,有效17例,无效3例,有效率95.00%;对照组痊愈8例,显效11例,有效6例,无效5例,有效率83.00%;两组有效率比较差异有显著性意义(P<0.05),治疗组疗效优于对照组.结论:益气健脾化瘀法治疗慢性胃炎疗效满意.%Objective:To discuss the therapeutic effects of the method of replenishing qi, activating spleen and eliminating blood stasis on the treatment of chronic gastritis. Methods:90 cases were randomly divided into two groups. The treatment group(60 cases) was treated by methods of replenishing qi,activating spleen and eliminating blood stasis,and the Chinese herbs were Danshen( Radix Salvia Miltior-rhiza) ,Tanxiang(Sandalwood) ,Sharen( Fructus amomi) ,Dangshen(Codonopsis pilosula) , Baizhu( White Atractylodes Rhizome) , Ful-ing(Poria) ,Zhiqiao(Fructus aurantii immaturus ) , Houpo ( Mangnolia officinalis ), Huanglian ( Goldthread ), Wuzhuyu ( Fructus evodi-ae) ,Baihe(Lily) ,Wuyao( Radix Linderae) , Gancao(liquorice). The control group(30 cases) was treated by Famotidine Tablets and Colloidal Bismuth Pectin Capsules. Results:In the treatment group,28 cases were cured, 12 achieved excellent effects, 18 were effective, 3 were ineffective and the effective rate was 95% ;in the control group,8 cases were cured, 11 achieved excellent effects,6 were effective,5 were ineffective and the effective rate was 83%. Comparison of the total effective rates between two groups showed that the difference had notable significance(P <0.05) ,and the curative effects of the treatment group was superior to the control group. Conclusion: The methods of

  10. Efficacy of Nourishing Yin and Lowering Adverse Qi Therapy in Treating COPD%中医滋阴降逆法治疗慢性阻塞性肺疾病的疗效观察

    Institute of Scientific and Technical Information of China (English)

    宿芳

    2013-01-01

    Objective:Under the guidance of TCM theory of evidence-based medicine , explore clinical efficacy of Yin-nourishing , qi-re-versing method in patients with chronic obstructive pulmonary disease .Methods:A total of 106 patients of chronic obstructive pulmonary disease were divided into the control group ( treated with conventional western medications such as oxygen , anti-infection meds , anti-spasmolysis and anti-asthma meds , meds for reduce cough phlegm and dilate bronchi );treatment group were treated with TCM decoction of Yin-nourishing, qi-reversing effect, in addition to conventional western medicine treatment .After a treatment course of 14 days, clini-cal efficacy was evaluated.Results:Symptoms (cough, sputum color and breathing, chest tightness,heart function change, white blood cells and neutrophils) improved significantly in treatment group than the control group (P<0.05).Conclusion:The clinical observa-tion showed that Yin-nourishing , qi-reversing method can promote improvement of clinical symptoms of chronic obstructive pulmonary disease, therefore provide new method and thoughts for COPD treatment .%目的:在中医辨证论治理论指导下,结合临床疗效,为滋阴降逆法在慢性阻塞性肺疾病患者的临床应用提供依据。方法:对106例慢性阻塞性肺疾病患者依据其意愿,分为对照组(用西医疗法)采用吸氧、抗感染、解痉平喘、止咳化痰、扩张支气管等西医常规治疗措施:治疗组(加用中医药疗法)在西医常规治疗措施基础上,加用滋阴降逆法中药汤剂治疗。14 d为1疗程,观察1个疗程结束后就临床疗效作出评价。结果:两组症状体征比较:治疗组在咳嗽、咳痰色、喘息、胸闷、心功能转归、白细胞及中性粒细胞的转归改善明显好于对照组症状改善。两组疗效比较,治疗组疗效优于对照组( P<0.05)。结论:本次临床观察结果表明,滋阴降逆法可以促进

  11. Study on Insulin Secretion's Characteristic of Stagnation of Liver Qi and Stomach Heat of Obesity Type 2 Diabetes%肥胖T2DM肝胃郁热证患者胰岛素分泌特点研究

    Institute of Scientific and Technical Information of China (English)

    赵昱; 陈良; 董柳; 毕桂芝; 仝小林

    2012-01-01

    Objective: Study on the insulin secretion's characteristic of stagnation of liver Qi and stomach heat of obesity type 2 diabetes was made to reveal pathological mechanism of TCM syndrome. Methods: We selected the patients of obese T2DM as subjects, observe the features of insulin - secretion through insulin tolerable test by contrast with normal person and obese person, observe the change of IRI,TI,PI in zero point? 30 minute points 120 minute point. Results-.The patients of stagnation of liver Qi and stomach heat of obesity type 2 diabetes' s insulin - secretion is low and delayed and especially in early - phase of insulin secretion, fasting PI of subjects is double than normal contrast groups , and subjects insulin secretion index and insulin sensitivity index are poor. Conclusion: Distinctive difference exists in the quality and quantity of insulin - secretion between the patients of stagnation of liver Qi and stomach heat of obesity type 2 diabetes and normal contrast group, it is the true reason that insulin resistance (IR) and impaired B - cell function makes subjects blood sugar very high, and it' s feasible to evaluate B - cell function by true insulin.%目的:研究肥胖T2DM的主要证型肝胃郁热证患者的胰岛素分泌特点,为探讨肝胃郁热证的科学内涵做一粗浅尝试.方法:通过胰岛素耐量实验,将肥胖T2DM肝胃郁热患者与正常组和肥胖组比较,检测0点、30min、120min免疫反应性胰岛素(IRI)、真胰岛素(TI)和胰岛素原(PI).结果:同对照组相比,肥胖2型糖尿痛肝胃郁热证患者胰岛素分泌低钝,延迟,平时相分泌远低于正常者;Homa -β细胞功能指教、胰岛素抵抗指数存在显著差异.结论:肥胖2型糖尿病肝胃郁热证患者胰岛素分泌的数量、质量及胰岛素分泌的时相性都存在明显的病理改变,证实胰岛β细胞功能减退及胰岛素抵抗双重因素导致该患者群血糖居高不下.同时本研究提示采用真胰岛素评

  12. 维生素E联合三七治疗早期糖尿病视网膜病变的临床观察%Clinical Observation on Vitamin E Capsule and SanQi in Treating Early Diabetic Retinopathy

    Institute of Scientific and Technical Information of China (English)

    邓洪; 谢青; 郑云燕; 王庆开

    2014-01-01

    Objective:To observe clinical effects of Vitamin E capsule and SanQi (Panax pseudo-ginseng) powder in treating early diabetic retinopathy (DR). Methods:Ninety patients (including 179 eyes) were randomized into three groups. 30 cases of the treatment group (60 eyes), who took Vitamin E capsule and SanQi powder;30 cas-es of the control group (60 eyes), who were administered with calcium dobesilate dispersible tablets;and 30 cases of routine treatment group (59 eyes). All the patients were treated for 120 days. Fundus examination, fluorescence fun-dus angiography, the examinations of sight and visual field of the patients were preformed before and after treating;at the same time, the functions of liver and kidney, blood rheology and others were detected. Results:Microvascular disease of the fundus and blood viscosity in both groups were improved, fundus edema and microaneurysm were re-lieved, the difference was significant when the treatment group was compared with the control group (P<0.05). Conclusion:Vitamin E capsule and SanQi powder could improve the state of ischemia and hypoxia in the patients with early DR, promote the absorption of retinal edema and microaneurysm and delay the loss of vision.%目的:观察维生素E胶囊联合三七粉治疗早期糖尿病视网膜病变的临床疗效。方法:将90例(179只眼)早期糖尿病视网膜病变患者随机分为3组。治疗组30例(60只眼),口服维生素E胶丸加三七粉;对照组30例(60只眼),口服羟苯磺酸钙分散片;常规治疗组30例(59只眼),仅对基础疾病进行治疗。用药时间120天。治疗前后对所有患者进行眼底检查及荧光素眼底血管造影、视力、视野检查,同时检测肝肾功能、血液流变学等指标。结果:治疗组和对照组的眼底微血管病变和血液黏度均得到一定程度的改善,眼底水肿减退,微血管瘤减少,与常规治疗组比较差异显著(P<0.05)。结论:维生素E加三

  13. Systematic Review on Treatment of Chronic Atrophic Gastritis by Reinforcing qi, Promoting Blood Circulation and Replenishing Yin%益气活血养阴法治疗慢性萎缩性胃炎的系统评价

    Institute of Scientific and Technical Information of China (English)

    刘婷; 刘福生; 张寅; 杜娜; 苏泽琦; 丁霞

    2015-01-01

    Objective:To systematically evaluate the efficacy of reinforcing qi ,promoting blood circulation and replenishing yin on treating chronic atrophic gastritis. Methods:Relevant Chinese and English literature of randomized clinical trials(RCTs) were reviewed via database. Trials were adopted if the Jadad scale score was 1 or more. Statistical heterogeneity between trials was evaluated by Revman 5.2. Heterogeneity of the in-cluded articles was tested to select proper effect models for calculation. Publication bias was investigated through visual inspection of funnel plots and Egger ’s regression model. Results:Nine RCTs including 846 patients were analyzed. The quality of RCTs are generally low. Compared with western medical treatment , reinforcing qi,promoting blood circulation and replenishing yin was better in improving the total effective rate of chronic gastritis. OR=4.57,95%CI (3.09~6.77). The difference was statistically significant (P<0.00001). Conclusion:Reinforcing qi,promoting blood circulation and replenishing yin may be superior to western medicines in improving total effective rate of patients with chronic atrophic gastritis. But more high quality research is needed to increase the strength of the evidence.%目的:系统评价中医益气活血养阴法治疗慢性萎缩性胃炎的疗效。方法:通过数据库检索中英文随机对照试验(RCT)文献,将Jadad积分≥1分的文章纳入研究,并提取纳入研究的特征信息。采用Revman 5.2软件进行Meta-分析,检验异质性,并根据异质性结果选择相应的效应模型,最后绘制漏斗图及Egger回归方程评定有无发表偏倚。结果:最终有9项RCT,共846例患者入选,文献质量普遍较低。益气活血养阴法治疗慢性萎缩性胃炎的总体疗效优于单纯的西医治疗,其汇总OR=4.57,95%CI(3.09~6.77),差异均具有统计学意义(P<0.00001)。结论:益气活血养阴法治疗慢性萎缩

  14. Brief Explanation of"Shi"of Bone in Qi Xiao Liang Fang(《奇效良方》Prescriptions of Wonderful Efficacy)%《奇效良方》骨之“势”浅解

    Institute of Scientific and Technical Information of China (English)

    郭玉晶; 陈居伟; 刘更生

    2012-01-01

    《奇效良方·正骨兼金镞门》是古代伤科文献中的重要资料,其所记载的人身“三百六十五骨节”中包括对于骨内物质“势、液、髓”的论述.这一论述在现存古代文献记载中较为少见,但它也清楚的表明古人对于人体构造是有过系统研究的,且观察比较仔细.文章对《奇效良方·正骨兼金镞门》所载“势、液、髓”中“势”进行了研究,通过“势”字的含义演变结合现代人体解剖中骨骼构造的研究进行系统分析,认为“势、液、髓”中“势”所指代相当于现代骨骼构造中骨小梁及部分骨密质结构.综上,文章意在引起中医学界对于中医学人体解剖生理的重视.%Volume 56 of Qi Xiao Liang Fang () Prescriptions of Wonderful Efficacy) ( ) is the essential material among the ancient literatures of traumatology. It records "three hundred and sixty - five joints"of the human body and discusses"Shi,Ye,Sui" ,the substances of bone. The statement is seldom seen in the present existing ancient documents, but it clearly indicates the systematic study of the human body structure and the intensive observation by the ancients. This paper focuses on the study on the understanding of" Shi" recorded in" Shi, Ye, Sui "of the Volume 56 of Qi Xiao Liang Fang (Prescriptions of Wonderful Efficacy) (). A systematic analysis was conducted through the study on the evolution on the meaning of" Shi" in combination with the skeleton structure in modern human body anatomy. It was viewed that" Shi"recorded in" Shi, Ye, Sui" implied the bone trabecula and a part of compact bone structure. In summary,the paper aims to draw the attention of the field of traditional Chinese medicine to the human anatomy and physiology of traditional Chinese medicine.

  15. Sedimentary facies of the Middle-Lower Devonian Niqiuhe Formation in East Ujimqin Qi of Inner Mongolia%内蒙古东乌旗地区中下泥盆统泥鳅河组沉积相研究

    Institute of Scientific and Technical Information of China (English)

    杜叶龙; 程银行; 李艳锋; 李敏; 胡晓佳; 张永; 张天福; 牛文超

    2015-01-01

    发育于内蒙古东乌旗地区的泥鳅河组,属于早中泥盆世沉积,厚度约1000,m,主要发育泥岩、粉砂岩和灰岩沉积,粉砂岩中常常发育大量腕足类和珊瑚生物化石。首次在本区发现风暴沉积和 Beaconites 遗迹化石:风暴沉积由下至上包括粒序层理段、平行层理段、丘状交错层理段和浪成波纹层理段4个层段;Beaconites遗迹化石具管壁和内部水平“V”字型的回填纹构造。通过对岩相、生物化石、风暴沉积和 Beaconites 遗迹化石的研究显示,东乌旗地区泥鳅河组为浅海相沉积。%The Middle-Lower Devonian Niqiuhe Formation,with about 1 000,m thick,developed at the East Ujimqin Qi of Inner Mongolia.It mainly consists of mudstone,siltstone and limestone.A great deal of brachiopoda and coral fossils are often found in the siltstone.Storm deposit and the trace fossil of Beaconites were found for the first time.The storm deposits consist from the bottom to the top of four seg_ments,namely graded bedding,parallel bedding,hummocky cross_bedding and wavy bedding.Beaco-nites is characterized by pipe wall and horizontal “V” back_packing structure.The research of petrofacies, fossils,storm deposits and Beaconites shows that the Niqiuhe Formation in East Ujimqin Qi area belongs to shallow sea facies.

  16. 益精汤治疗气滞血瘀型少弱精症疗效观察%Curative Effect Observation on Yijing Decoction in Treatment of Qi Stagnation and Blood Stasis Type of Oligoasthenotspermia

    Institute of Scientific and Technical Information of China (English)

    王旭初; 郑加涛

    2013-01-01

    目的:探讨益精汤治疗少弱精症(气滞血瘀型)的机理,为中医药治疗少弱精症提供理论依据.方法:将60例少弱精患者随机分成两组.治疗组30例,予益精汤口服,每日1剂,早晚分服.对照组30例,予左卡尼汀口服液10mL,口服,2次/d.两组均以4周为1个疗程,观察3个疗程.观察患者在治疗前后的精液量、精液密度及活动力等指标.结果:治疗后两组精子参数各项指标中精液量、密度、成活率和活力均有改善,与治疗前比较,差异有显著性意义.结论:益精汤对于少弱精症(气滞血瘀型)患者精液参数的各项指标均有较好的改善,总有效率及各项精液参数均优于左卡尼汀口服液组.%Objective:To study the mechanism of Yijing Decoction in the treatment of asthenospermia (Qi stagnation and blood stasis type) and TCM Oligoasthenotspermia and provide a theoretical basis.Methods:60 cases of small weak sperm were randomly divided into two groups.The treatment group with 30 cases,was treated with Yijing Decoction orally,1 agent a day in the moming and evening.30 cases of the control group were given 10 mL levocarnitine oral liquid,twice a day.4 weeks was 1 course,and there were 3 courses.Patients were observed before and after the treatment in the semen volume,density and activity index.Results:After treatment,sperm parameters indicators in the semen volume,density,survival rate and activity of both were improved,compared with those before treatment,there were significant differences.Conclusions:Yijing Decoction for asthenozoospermia (Qi stagnation and blood stasis type) can improve semen parameters.The total efficiency and the semen parameters were superior to those of levocarnitine oral liquid group.

  17. The Cultural Characteristics of Yi Medicine from the Medical Literature:Qi Gushu%从贵州彝族医学文献《启谷署》看彝族“医药”文化特色

    Institute of Scientific and Technical Information of China (English)

    朱国祥; 徐俊飞

    2015-01-01

    Yi nationality is one of the seventeen native ethnic minorities in Guizhou.The population, language and culture of the Yi nationality in Guizhou are introduced briefly.The Yi literature of the Qi Gushu , whose version, content and other relevant are described.This paper mainly analyzes the charac-teristics of the Qi Gushu from five different angles:the Yi medicine"Five Body"theory, the curing effect of prescription, the maturity of a prescription, the simple characteristics of Yi Medicine, the theory origin between the Yi medicine and traditional Chinese medicine.Yi medicine is not only an important part of the Chinese medical treasures, also has made outstanding contributions to the health of the Yi people.In the development of national medicine industry, the question how to make use of the national medical re-sources should be paid much attention to.%彝族是贵州十七个世居少数民族之一,文中首先就贵州彝族的人口、语言文化略作介绍,并就彝医学文献的《启谷署》版本、内容等相关情况作了说明。论文重点就彝医学文献《启谷署》的特色作了分析,即从彝医学中“五体”理论、方剂的治愈效果、方剂的成熟性、彝医药简单性、彝医学理论与中医学理论的渊源关系等五个方面来分析。彝族医药文献不仅是中华医药文化宝库中重要组成部分,也为彝族人民健康事业作出了卓越的贡献。在开发民族医药过程中,如何利用民族医药文献资源是我们值得注意的问题。

  18. 基于治疗便秘方剂的频次分析探讨便秘从气津论治理论%Prescription of treating constipation-based frequency analysis to explore constipation from qi theory

    Institute of Scientific and Technical Information of China (English)

    颜帅; 钱海华; 陈映辉; 乐音子; 孙明明; 王晓鹏

    2016-01-01

    目的:通过运用频次分析方法对治疗便秘的中药复方进行研究,为临床治疗便秘提供参考。方法以南京中医药大学图书馆中医药在线中国方剂数据库为检索对象,对相关中药复方,分析后统计有效方药。结果数据库中共纳入方剂中含有“大便秘涩”463首,单味中药总计248味。(制)大黄、(制)甘草、当归、黄芩、火麻仁、枳实等在单味药中频次较高。结论中药复方以滋阴增液、补气养血类中药为主,推测调畅气机(气),生津润燥(津)为治疗便秘的关键治法,以此为基础加减化裁在中医临床上效果显著。%Objective To observe the general studies on Chinese medicine and prescription for prevention and treatment of constipation from and provide reference for the clinical treatment of constipation. Methods Taking the li-brary of Nanjing University of Chinese Medicine of Chinese medicine online Chinese prescription database,traditional Chinese medicine compound,analysis of statistical effective prescription. Results The database included prescription contains“constipation”463,single herb total 248. Rhubarb,licorice,angelica sinensis,baikal skullcap root,fructus cannabis,Zhishi in single medicine intermediate times higher. Conclusion Ziyin liquid,Qi nourishing increasing herbs,speculated that regulating qi shengjin runzao as the key treatment of constipation,on the basis of addition and subtraction cut effect in Chinese medicine clinical significant.

  19. The Research Methodology of Qi Xia's History Research Methodology%从《历史研究法》看漆侠先生的治学之路——纪念漆侠先生逝世10周年

    Institute of Scientific and Technical Information of China (English)

    申慧青

    2011-01-01

    History Research Methodology,which was finished by Qi Xia in his later years,embodied his ideas and methods in history research.In this book,Mr.Qi Xia discussed the scientific properties and methodology of history,its development in China,etc.History Research Methodology is based on Qi Xia's practical experience in years of industrious historical research.The historical cases provide answers to the common questions.Therefore,this book is worth reading for historical researchers.%《历史研究法》是漆侠先生晚年的重要著作,是他治史思想与方法的集中体现。在书中,漆侠先生就历史的科学属性、历史学的研究方法、中国史学发展历程等几个问题,作了深入浅出的分析和总结。《历史研究法》是漆侠先生基于几十年来兢兢业业研究历史的实际经验而撰写的著作,书中所举每一处实例,都是针对历史研究中常见问题的解答。这本书,值得每一位历史研究者细细品读。

  20. 经络刮痧联合刺络放血治疗气滞血瘀型颈椎病疗效观察%Efficacy Observation on Scraping Combined with Blood-letting Therapy for Cervical Spondylosis of Qi Stagnation and Blood Stasis

    Institute of Scientific and Technical Information of China (English)

    何宏伟

    2014-01-01

    目的:观察经络刮痧联合刺络放血治疗气滞血瘀型颈椎病的疗效。方法:47例气滞血瘀型颈椎病患者均行经络刮痧联合刺络放血治疗,观察其临床疗效。结果:治愈9例,好转36例,无效2例,总有效率为95.7%。结论:经络刮痧联合刺络放血治疗气滞血瘀型颈椎病疗效显著。%To observe the efficacy of scraping combined with blood-letting therapy for cervical spondylosis of qi stagnation and blood sta-sis. Methods:47 cases of patients with cervical spondylosis of qi stagnation and blood stasis were all treated by scraping combined with blood-letting therapy, and observed their efficacy. Results:9 cases were cured, 36 cases had turned better, and 2 cases invalid, the total effective rate was 95.7%. Conclusion:The treatment of scraping combined with blood-letting therapy has significant curative effect on cervical spondylosis of qi stagnation and blood stasis.

  1. 益气活血温阳通痹法治疗胸痹临床体会%Chest Discomfort Treated with Method of Notifying Qi Activating Blood Warming Yang and Tongbi

    Institute of Scientific and Technical Information of China (English)

    宁永滨

    2011-01-01

    [目的]观察益气活血温阳通痹法治疗胸痹的疗效.[方法]以益气活血温阳通痹为治疗大法加减治疗我院2005年3月至2009年10月62例胸痹患者,并进行临床观察.[结果]治愈36例,好转22例,2例无愈,总有效率为92%.[结论]益气活血、温阳通痹法治疗胸痹疗效显著.%[Objective] To observe the cure effect of the method of notifying Qi activating blood wanning Yang and Tongbi on chest discomfort.[Method] Apply the said method to 62 cases, then make clinical observation. [Result] 36 cases were cured, 22 better, total effective rate was 92%,and 2 cases failed. [Conclusion] The method has marked cure effect on chest discomfort.

  2. A Comparison of Man-of-letters Style in Ceramic Paintings between Wang Yeting and Wang Qi%汪野亭与王琦瓷绘文人画风格异同寻绎

    Institute of Scientific and Technical Information of China (English)

    林文贤

    2015-01-01

    汪野亭和王琦同为民国时期景德镇著名的瓷艺团体——“珠山八友”的成员,而且他们的作品具有同工异曲之妙,一方面他们有着共同的文人画艺术追求,另一方面又因创作题材、个人气质的不同而各自在诗韵、书味、画意、印趣等方面形成了不同的审美旨趣。%Wang Yeting and Wang Qi are both the members of the “Eight Friends of Zhushan”, a famous group of ceramic painting in the Republic of China Period. Their works made the same achievements by different methods and they have common artistic pursuit of man-of-letters painting style. However,because of the different subject matters and personal temperament they showed distinct aesthetic taste in the field of poem, calligraphy, painting and seal taste.

  3. Restricted views on Methodology of Composition above Middle School written by Liang Qi-chao%梁启超《中学以上作文教学法》管窥

    Institute of Scientific and Technical Information of China (English)

    夏梦薇

    2014-01-01

    The Methodology of Composition above Middle School written by Liang Qi-chao basically discussed the basic principles of writing、writing methods of various articles and writing didactics. The realistic meaning is to guiding the composi-tion teaching:avoid idealizing、widespread writing knowledge、focus on practicality of writing;The writing training needs to be put quality before quantity,seek for greater perfection;In the composition evaluation,we should remember student-oriented, pay attention to pluralism and democracy.%梁启超《中学以上作文教学法》主要论述了写作的基本原则、各类文章的写作方法、作文教授法三方面的内容。其现实意义在于指导当下的作文教学:切忌理想化,要普及写作知识,注重写作的实用性;对于写作训练应做到宁缺毋滥,精益求精;在作文评价方面,要以学生为本,重多元,讲民主。

  4. Simultaneous Qualitative and Quantitative Analysis of Multiple Chemical Constituents in YiQiFuMai Injection by Ultra-Fast Liquid Chromatography Coupled with Ion Trap Time-of-Flight Mass Spectrometry.

    Science.gov (United States)

    Liu, Chunhua; Ju, Aichun; Zhou, Dazheng; Li, Dekun; Kou, Junping; Yu, Boyang; Qi, Jin

    2016-05-18

    YiQiFuMai injection (YQFM) is a modern lyophilized powder preparation derived from the traditional Chinese medicine Sheng-mai san (SMS) used for treating cardiovascular diseases, such as chronic heart failure. However, its chemical composition has not been fully elucidated, particularly for the preparation derived from Ophiopogon japonicus. This study aimed to establish a systematic and reliable method to quickly and simultaneously analyze the chemical constituents in YQFM by ultra-fast liquid chromatography coupled with ion trap time-of-flight mass spectrometry (UFLC-IT-TOF/MS). Sixty-five compounds in YQFM were tentatively identified by comparison with reference substances or literature data. Furthermore, twenty-one compounds, including three ophiopogonins, fifteen ginsenosides and three lignans were quantified by UFLC-IT-TOF/MS. Notably, this is the first determination of steroidal saponins from O. japonicus in YQFM. The relative standard deviations (RSDs) of intra- and inter-day precision, reproducibility and stability were analysis of ten batches of YQFM. The developed approach can provide useful and comprehensive information for quality control, further mechanistic studies in vivo and clinical application of YQFM.

  5. Identification of schisandrin as a vascular endothelium protective component in YiQiFuMai Powder Injection using HUVECs binding and HPLC-DAD-Q-TOF-MS/MS analysis.

    Science.gov (United States)

    Li, Fang; Tan, Yi-Sha; Chen, Hong-Lin; Yan, Yan; Zhai, Ke-Feng; Li, Da-Peng; Kou, Jun-Ping; Yu, Bo-Yang

    2015-09-01

    YiQiFuMai Powder Injection (YQFM) is a re-developed preparation based on the well-known traditional Chinese medicine formula Sheng-mai-san. It has been widely used for the treatment of cardiovascular disease with definite clinical efficacy in China, but its bioactive molecules remain obscure. In this study, an effective method has been employed as a tool for screening active components in YQFM, using human umbilical vein endothelial cells (HUVECs) extraction and liquid chromatography coupled with electrospray ionization quadrupole time-of-flight tandem mass spectrometry (Q-TOF MS/MS). Nine compounds, which could interact with HUVECs, were identified as ginsenosides Rb1, Rc, Rb2, Rd, 20(S)-Rg3, 20(R)-Rg3, Rk1/Rg5 and schisandrin by comparing with reference substances or literature. In vitro assays showed that schisandrin at concentrations of 10-100 μM protected HUVECs from hypoxia/reoxygenation (H/R) injury, increased cell viability, nitric oxide (NO) content and decreased lactate dehydrogenase (LDH) leakage, malonaldehyde (MDA) content and ROS generation. Moreover, schisandrin pretreatment inhibited cell apoptosis, as evidenced by inhibiting activation of caspase-3 and increasing the Bcl-2/Bax ratio. These data indicate that HUVECs biospecific extraction coupled with HPLC-ESI-Q-TOF-MS/MS analysis is a reliable method for screening potential bioactive components from traditional Chinese medicines. Meanwhile, the vascular endothelium protective property of schisandrin might be beneficial for the treatment of cardiovascular disease.

  6. Effect of Da-Cheng-Qi Decoction on the Repair of the Injured Enteric Nerve-Interstitial Cells of Cajal-Smooth Muscle Cells Network in Multiple Organ Dysfunction Syndrome

    Science.gov (United States)

    Liu, Mu-Cang; Xie, Ming-Zheng; Ma, Bin; Qi, Qing-Hui

    2014-01-01

    Wistar rats were randomly divided into control group, multiple organ dysfunction syndrome (MODS) group, and Da-Cheng-Qi decoction (DCQD) group. The network of enteric nerves-interstitial cells of Cajal- (ICC-) smooth muscle cells (SMC) in small intestine was observed using confocal laser scanning microscopy and transmission electron microscopy. The results showed that the numbers of cholinergic/nitriergic nerves, and the deep muscular plexus of ICC (ICC-DMP) and connexin43 (Cx43) in small intestine with MODS were significantly decreased. The network integrity of enteric nerves-ICC-SMC was disrupted. The ultrastructures of ICC-DMP, enteric nerves, and SMC were severely damaged. After treatment with DCQD, the damages were repaired and the network integrity of enteric nerves ICC-SMC was significantly recovered. In conclusion, the pathogenesis of gastrointestinal motility dysfunction in MODS in part may be due to the damages to enteric nerves-ICC-SMC network and gap junctions. The therapeutic mechanism of DCQD in part may be that it could repair the damages and maintain the integrity of enteric nerves ICC-SMC network. PMID:25477993

  7. Xiang-Qi-Tang and its active components exhibit anti-inflammatory and anticoagulant properties by inhibiting MAPK and NF-κB signaling pathways in LPS-treated rat cardiac microvascular endothelial cells.

    Science.gov (United States)

    He, Chang-Liang; Yi, Peng-Fei; Fan, Qiao-Jia; Shen, Hai-Qing; Jiang, Xiao-Lin; Qin, Qian-Qian; Song, Zhou; Zhang, Cui; Wu, Shuai-Cheng; Wei, Xu-Bin; Li, Ying-Lun; Fu, Ben-Dong

    2013-04-01

    Xiang-Qi-Tang (XQT) is a Chinese herbal formula containing Cyperus rotundus, Astragalus membranaceus and Andrographis paniculata. Alpha-Cyperone (CYP), astragaloside IV (AS-IV) and andrographolide (AND) are the three major active components in this formula. XQT may modulate the inflammatory or coagulant responses. We therefore assessed the effects of XQT on lipopolysaccharide (LPS)-induced inflammatory model of rat cardiac microvascular endothelial cells (RCMECs). XQT, CYP, AS-IV and AND inhibited the production of tumor necrosis factor alpha (TNF-α), intercellular cell adhesion molecule-1 (ICAM-1) and plasminogen activator inhibitor-1 (PAI-1), and up-regulated the mRNA expression of Kruppel-like factor 2 (KLF2). XQT and CYP inhibited the secretion of tissue factor (TF). To further explore the mechanism, we found that XQT, or its active components CYP, AS-IV and AND significantly inhibited extracellular signal-regulated kinase (ERK), c-jun NH2-terminal kinase (JNK) and p38 phosphorylation protein expression as well as decreased the phosphorylation levels of nuclear factor κB (NF-κB) p65 proteins in LPS-stimulated RCMECs. These results suggested that XQT and its active components inhibited the expression of inflammatory and coagulant mediators via mitogen-activated protein kinase (MAPKs) and NF-κB signaling pathways. These findings may contribute to future research on the action mechanisms of this formula, as well as therapy for inflammation- or coagulation-related diseases.

  8. Effect of Shugan Jianpi Granule(舒肝健脾颗粒) on Gut Mucosal Serotonin-positive Cells in Patients with Irritable Bowel Syndrome of Stagnated Gan-qi Attacking Pi Syndrome Type

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    Objective:To evaluate the effect of Shugan Jianpi Granule (舒肝健脾颗粒,SJG) on the number of gut mucosal serotonin-positive cells (5-HT+C) in patients with irritable bowel syndrome (IBS) of stagnated Gan-qi attacking Pi (SGAP) syndrome type.Methods:Twenty-four patients were randomized equally into three groups.All were treated with the basic conventional treatment by cognition-behavior therapy with assistance of lactein 3 tablets thrice a day.Additionally,24 g of SJG was given three times a day to group A,and the same dosage of SJG and Smecta 15 g thrice a day was given to group B,while no additional treatment was given to the control group.The number of 5-HT+C was measured respectively before and two weeks after treatment by immunohistochemical method.Results:The number of 5-HT+C decreased after treatment in all the three groups (P<0.05),but the decrement was more significant in the two test groups than in the control group (P<0.05 and P<0.01,respectively),while comparison of 5-HI+C between the two test groups showed insignificant difference (P>0.05).Conclusion:SJG can reduce the number of 5-HT+C in IBS patients of SGAP syndrome type,and its effect is enhanced when used in combination with Smecta.

  9. Simultaneous Qualitative and Quantitative Analysis of Multiple Chemical Constituents in YiQiFuMai Injection by Ultra-Fast Liquid Chromatography Coupled with Ion Trap Time-of-Flight Mass Spectrometry

    Directory of Open Access Journals (Sweden)

    Chunhua Liu

    2016-05-01

    Full Text Available YiQiFuMai injection (YQFM is a modern lyophilized powder preparation derived from the traditional Chinese medicine Sheng-mai san (SMS used for treating cardiovascular diseases, such as chronic heart failure. However, its chemical composition has not been fully elucidated, particularly for the preparation derived from Ophiopogon japonicus. This study aimed to establish a systematic and reliable method to quickly and simultaneously analyze the chemical constituents in YQFM by ultra-fast liquid chromatography coupled with ion trap time-of-flight mass spectrometry (UFLC-IT-TOF/MS. Sixty-five compounds in YQFM were tentatively identified by comparison with reference substances or literature data. Furthermore, twenty-one compounds, including three ophiopogonins, fifteen ginsenosides and three lignans were quantified by UFLC-IT-TOF/MS. Notably, this is the first determination of steroidal saponins from O. japonicus in YQFM. The relative standard deviations (RSDs of intra- and inter-day precision, reproducibility and stability were <4.9% and all analytes showed good linearity (R2 ≥ 0.9952 and acceptable recovery of 91.8%–104.2% (RSD ≤ 5.4%, indicating that the methods were reliable. These methods were successfully applied to quantitative analysis of ten batches of YQFM. The developed approach can provide useful and comprehensive information for quality control, further mechanistic studies in vivo and clinical application of YQFM.

  10. 《齐东野语》中的亲属称谓语研究%The Study of Relative Appellation Terms inQi Dong Ye Yu(齐东野语)

    Institute of Scientific and Technical Information of China (English)

    吕玲娣

    2016-01-01

    The relative appellation terms are the tags of the relationship between the family and relatives. These relative appellation terms can distinguish old and young, superior and inferior, close and distant. As one of the classic during The Notes of Song Dynasty, the relative appellation terms inQi Dong Ye Yuare numerous. They are not only the calling sign, but also reflect the mutual relationship between families and members of the same clan in the Song Dynasty. And these relative appellation terms can help us understand the social culture of Song Dynasty.%亲属称谓是人们在家庭内部和亲属往来中相互关系的标记,用以别长幼、分尊卑和辨亲疏。《齐东野语》作为宋人笔记名著之一,其亲属称谓语数量众多,这些亲属称谓语不仅仅是简单的称呼符号,也从一个侧面反映了宋代家庭、亲族中人与人的相互关系,有助于我们了解宋代的社会风貌。

  11. Ecological Restoration Oriented Planning for Plant Landscape of Daying Section of Qi River%以生态恢复为导向的郪江流域大英段植物景观规划

    Institute of Scientific and Technical Information of China (English)

    冯美文; 牟江

    2014-01-01

    River plants as the basic nature elements , plays an important role in building and maintaining the river ecological system stability .By taking river plants as research subjects , the definition of ecologi-cal restoration , restoration models and its characteristics are made .Then, taking the Daying section of Qi river as the carrier , a study on the plant landscape planning of the river has been carried out , and the plant evaluation and planning guided by overall strategy also been introduced in this paper .%流域植被作为基础的自然“本底”,在构建和维护河流生态系统稳定方面有着重要作用。通过对生态恢复定义及模式的探析,以流域植物为主要分析对象,浅析其界定与特征。以郪江流域大英段生态恢复项目为载体,展开流域植物景观规划研究,阐述总体策略引导下的植物评价及规划。

  12. 益气养阴方抗肿瘤转移及对肿瘤细胞VEGF表达的影响%Effect of reinforcing Qi and nourishing Yin prescription on anti-tumor metastasis and VEGF expression in tumor cells

    Institute of Scientific and Technical Information of China (English)

    孙静

    2009-01-01

    Objective: To study the role of reinforcing Qi and nourishing Yin prescription on anti-tumor metastasis and vascuhr endothelial growth factor(VEGF) in tumor colls. Methods:Cervical carcinoma U14 spontaneous metastasis models were adopted. The effect of tumor metastasis was observed in reinforcing Qi and nourishing Yin prescription group,compared with model group and western medicine group. The expression of VEGF in cervical carcinoma was investigated by immunohistochemical and morphological analytics methods. Results: Reinforcing Qi and nourishing Yin preseriptian group has no strong positive and 11 medium positive(22%) in the expression of VEGF. The expression of VEGF in reinforcing Qi and nourishing Yin prescription group was lower than that in control group,there was statistical difference(P<0.01). Conclusion: Reinforcing Qi and nourishing Yin prescription has significant inhibitory effects on angiogenesis induced by tumor cells. The down-regulation of VEGF expression may be one of its mechanisms for inhibiting tumor angiogenesis.%目的:研究益气养阴方抗肿瘤转移及对肿瘤细胞血管内皮生长因子(VEGF)表达的效应.方法:复制小鼠子宫颈癌U14自发性转移模型,观察益气养阴方对肿瘤转移的影响并与造模组和西药组比较,采用免疫组织化学法及其组织形态学定量分析方法研究VEGF在子宫颈癌中的表达.结果:益气养阴方组VEGF表达无强阳性者,中阳性11个(22%),益气养阴方组VEGF的表达明显低于对照组,有显著性差异(P<0.01).结论:益气养阴方对肿瘤血管形成有明显抑制作用,降低VEGF的表达可能是其抑制肿瘤血管形成的主要机制之一.

  13. An Investigation on Tang Junyi’ s Article Chuanshan’ s Respect for Life, for Qi, and for Affection%唐君毅先生之船山人性论浅释(下)①--探《船山之尊生尊气与尊情才义》

    Institute of Scientific and Technical Information of China (English)

    蔡家和

    2015-01-01

    唐先生认为,船山的两端一致说,肯定气禀,认为恶的来源不在于欲求,而在欲求的不中节,以情才之交的不当位而下流。耳目口鼻与欲求,不是吾人当该舍弃的对象,而是当吾人把情才之交,流荡而为机械式,下委而不能中节所造成的。故唐先生对船山论气质与恶的关系所作诠释发挥了船山重气的义理,视气是可以保住的,重点在于别低贱气,独尊性,因性为孤立,如此则否定世间气化,而且情才也要依于性善的引导,才能不流于恶。%This study intends to explain the relationship between temperament and evil in Chuanshan’ s ar-guments, and mainly uses the interpretation of Tang Junyi’s.Tang Junyi suggested that, Chuanshan’s theo-ry of consistency at both ends could confirm the existence of Qi in human body, and argued that the origin of evil is not the pursuit of desire, but the lack of morality in the pursuit of desire.Those who inappropriately use other people ’ s affection and talent are scurrilous.What people should give up are not ears, eyes, mouth, nose, and desire, but the misuse or mechanical use of other people’ s affection and talent, as well as the lack of morality.Therefore, Tang Junyi and Chuanshan both attached importance to the philosophy of Qi, and suggested that Qi can be preserved.However, one should not belittle Qi, and overestimate nature to isolate nature.If so, the flow of Qi in the world will be denied.Moreover, affection and talent should also be guided by goodness of nature.In this way, they will not become evil.

  14. 芪柴煎剂对变应性鼻炎大鼠血清IL-4,IFN-γ影响的实验研究%Effect of Qi Chai decoction on serum IL-4, IFN-γlevel in allergic rhinitis rats

    Institute of Scientific and Technical Information of China (English)

    胥彪; 胡文健

    2015-01-01

    Objective: To study the influence of Qi Chai decoction on serum IL-4, IFN-γ level of allergic rhinitis model of rats so as to explore its role and efficacy in treating allergic rhinitis. Methods:Rats with allergic rhinitis were made by ovalbumin as sensitizing agent. 40 healthy adult SD rats were randomly divided into five groups(8 rats each):normal control group low-dose and high dose Qi Chai decoction groups,loratadine group, and model control group. Corresponding mjodel control given for 14 consecutive days in each group. Then the serum IL-4 and IFN-γ contents were tested by ELISA. Results: Compared with model control group,the serum IL-4 levels of low dose and high dose Qi Chai decoction groups and desloratadine group were significantly lower, and there were significant differences (P<0.05), and IL-4 level of low dose Qi Chai decoction group was higher than that of high dose group (P< 0.05). Compared with model control group, the serum IFN-γ level of low dose and high dose Qi Chai decoction groups, and the desloratadine group were significantly higher (P< 0.05). Compared with high dose group, the serum IFN-γ level of low dose Qi Chai decoction group and loratadine group were significantly lower (P< 0.05). Conclusion: The Qi Chai decoction can down-regulate the serum IL-4 levels and up-regulate the serum IFN-γlevels of the rats with allergic rhinitis.%目的::研究芪柴煎剂(自拟方)对变应性鼻炎大鼠模型血清IL-4、IFN-γ的影响,探讨其对变应性鼻炎大鼠的作用疗效。方法:应用卵清蛋白将实验大鼠制作成变应性鼻炎模型,随机分为正常对照组(A组)、芪柴煎剂低剂量组(B组)、高剂量组(C组)、地氯雷他定组(D组)、模型对照组(E组)各8只。连续14 d分别给予对应的药物,A组、E组以蒸馏水替代。用双抗体夹心ELISA法检测血清IL-4、IFN-γ的含量。结果:各实验组血清IL-4含量较模型对照组明显偏低,差异均有统计学意义(P<0.05)

  15. 益气通阳方治疗病态窦房结综合征临床观察%Clinical Observation on Prescription of Supplementing Qi and Activating Yang in Treating Sick Sinus Syndrome

    Institute of Scientific and Technical Information of China (English)

    刘金凤; 汪艳丽; 徐利亚; 展慧慧; 刘如秀; 刘志明

    2014-01-01

    Objective To observe the clinical therapeutic efficacy of prescription of supplementing qi and activating yang on sick sinus syndrome. Methods According to the random number table, 231 patients with sick sinus syndrome were randomly divided into treatment group and control group. One hundred and fifty patients in the treatment group were given the Chinese herbal medicine while the other 81 patients in the control group were given atropine. The therapeutic course was four weeks in each group. The changes of clinical manifestations and electrocardiogram (24 h Holter monitoring ECG) of two groups were compared. Results The total effectiveness of treatment group was 98.67% (148/150), the control group was 41.98% (34/81), there was a significant difference in the clinical curative efficacy (P<0.01). The total effective rate of the treatment group was 87.3%(131/150) and that of the control group was 35.9%(29/81), and the average increases of heart rates in 24 hours were 9/min and 4/min, respectively. There was significant difference between the two groups (P <0.05). Conclusion The prescription of supplementing qi and activating yang was effective in improving the clinical symptoms and heart rates of patients with sick sinus syndrome.%目的:观察益气通阳方治疗病态窦房结综合征的临床疗效。方法将231例病态窦房结综合征患者采用随机数字表法随机分为治疗组和对照组。治疗组150例,予益气通阳方,每日2次口服;对照组81例,予阿托品,0.3 mg/次,每日3次口服。2组疗程均为4周。比较2组临床症状及24 h动态心电图变化。结果治疗组总有效率为98.67%(148/150),对照组为41.98%(34/81),2组临床疗效比较差异有统计学意义(P<0.01);24 h动态心电图显示,治疗组和对照组心率提高总有效率分别为87.3%(131/150)和35.9%(29/81),其24 h平均心率分别增加9次/min和4次/min,2组比较差异有统计学意义(P<0.05)。结论益气通阳方可改善病态窦

  16. 东乌旗中铁陨石硅酸盐地球化学特征及对成因的启示%GEOCHEMISTRY OF SILICATES IN THE DONG UJIMQIN QI MESOSIDERITE AND THE IMPLICATIONS FOR ITS ORIGIN

    Institute of Scientific and Technical Information of China (English)

    聂喜柯; 孔屏

    2013-01-01

    东乌旗中铁陨石是1995年在内蒙发现的、为数不多的降落型中铁陨石,由金属-硫化物和硅酸盐相紧密混合而成。硅酸盐相由角砾部分(主要为角砾状橄榄石和辉长岩岩屑)和非角砾部分组成。岩相学特征、主量元素成分及REE地球化学特征表明角砾状橄榄石、非角砾橄榄石和辉长质硅酸盐(辉长岩岩屑和除橄榄石外的非角砾部分)三者可能分别结晶自不同的岩浆源区。进一步的分析表明Mg含量非常高的角砾状橄榄石可能来自一个分异小行星的橄榄岩质地幔,非角砾橄榄石和辉长质硅酸盐可能和HED陨石具有相同的母体Vesta小行星。冲击碰撞导致两个小行星的物质发生了混合。冲击作用产生的高温(约1200-1450℃)使得被撞击小行星表壳玄武质和辉长质岩石发生混合重熔,熔体结晶后形成中铁陨石的辉长质硅酸盐。该温度下非角砾橄榄石和角砾状橄榄石均未发生重熔。该模型较好地解释了角砾状橄榄石、非角砾橄榄石和辉长质硅酸盐三者之间的不平衡现象。%The Dong Ujimqin Qi meteorite is a rare mesosiderite that fell in Inner Mongolia , China in 1995.It consists of intimately mixed metal-sulfide and silicates .Silicates in the mesosiderite are composed of clasts ( mainly olivine and gabbro ) with a gabbroic matrix .Petrographic and REE characteristics and major element compositions show that the olivine clasts , matrix olivine and gabbroic rocks ( including gabbro clasts and gabbroic matrix ) may have crystal-lized from different magmas .Olivine clasts, with high Mg contents, may be derived from the dunite mantle of a dif-ferentiated asteroid , whereas matrix olivine and gabbroic rocks may be from the same parental asteroid , e.g, the Vesta asteroid .An impact event may have led to the mixture of materials from these two asteroids .During the bom-bardment , temperature rose to 1 200-1 450℃and the

  17. Correlation between incidence of typhoid fever and climate changes in Beijing from the perspective of Six-qi%从六气角度探讨北京地区伤寒与气象变动的相关性

    Institute of Scientific and Technical Information of China (English)

    黄羚; 刘柳青; 宋娜; 吕智燚; 刘张博方; 贺娟

    2014-01-01

    Objective To investigate the correlation between incidence of typhoid fever and climate changes in Beijing from the perspective of Six -qi.Methods Meteorological data and clinical data were collected in Beijing from 1985 to 2004 including:average temperature , water-vapor pressure , relative humidity , precipitation and wind speed.Each year was divided into six stages from the perspective of Six -qi theory.Correlation between incidence of typhoid fever and climate changes was analyzed with SPSS 19.0 in method of one-factor ANOVA and multiple linear regression.Results The outcome number of typhoid fever in the third stage was larger than other stages .The inci-dence of typhoid fever was positively correlated with average temperature , relative humidity, water-vapor pressure andprecipitation,thecorrelationwasstatisticallysignificant(P<0.05).Conclusion :Theincidenceoftyphoid fever in Beijing was correlated with climate changes .Different meteorological factors inordinately influenced the inci-dence of typhoid fever .It is feasible to predict the prevalence of typhoid fever by using the meteorological data in pre -vious year .%目的:根据中医运气学说理论,从六气角度探讨伤寒发病与气象变动的相关性,讨论各气象因素对伤寒发病的影响。方法回顾北京市1985-2004年907例伤寒发病人数及相应的气象资料,包括平均气温、平均降水量、平均湿度、平均水汽压及平均风速。将各气象因子与伤寒发病数据按六气分段进行相关性分析。分别将前一年和当年的气象资料与伤寒发病人数进行单因素相关分析,将相关性较高的气象因子纳入多元逐步回归方程,建立回归模型,比较二者的关联性。结果终之气、初之气为伤寒低发时期,三之气和四之气期间为高发时期,三之气最高。伤寒的发病与前一年平均气温、平均降水量、平均湿度、平均水汽压呈正相关,与

  18. To Meet on the Way to Language---Analyze the Linguistic of Heidegger and "Qi Wu Lun"%语言路上的相遇--海德格尔和庄子《齐物论》研究

    Institute of Scientific and Technical Information of China (English)

    连悦

    2015-01-01

    In the view of the language issue,Zhuangzi and Heidegger have the high degree of identity.In their view,the start-ing point of all languages is not people,but language itself.People are able to understand Tao and existence in the language. By means of analysis of the language of Heidegger,Zhuangzi's "Qi Wu Lun"is discussed.And expound the correspond of their language ways in many aspects.Their language is not one description of things,but the communication of mind and matter.A-bandon paranoid and make it a natural appearance.%在语言问题的看法上,庄子与海德格尔存在着高度的同一性。在他们看来,一切语言的出发点并不是人,而是语言本身,人们能够在语言中去体悟道、体悟存在。这里借助海德格尔对语言的分析对庄子《齐物论》之言进行了探讨,从多方面阐述出二者在语言道路上的契合。他们的语言不是人对事物的描述,而是心与物的交流,放弃偏执,使其自然显现。

  19. 从《歧路灯》看清中叶开封的商业活动%See the Business Activities of Kaifeng in the Mid-Qing Dynasty from Qi Lu Deng

    Institute of Scientific and Technical Information of China (English)

    李俊锋

    2015-01-01

    In the Mid-Qing dynasty,the commodity trade in Kaifeng is highly prosperous. There are many descriptions of social e-conomy in the Henan local novel Qi Lu Deng. It shows the panorama of Kaifeng trade at that time. And it has in-depth descriptions of the commercial development,commercial transportation route, and businessmen operating in the industry. In the novel, foreign busi-nessmen in Henan commercial development occupy the main position. They are mainly engaged in silk trade, pawnshop. Local busi-nessmen mainly engaged in medicine and food operations. Guildhall is an important stage for foreign guest businessman social. It plays a important role of the carrier and the media in economic activity.%清中叶,开封的商品贸易高度繁荣。河南本土小说《歧路灯》中有大量关于清中叶社会经济风貌的描写,展现了当时开封贸易的全貌,诸如商业的发展、商业交通路线、商人经营行业等都有深入描写。小说中的客商在当时河南商业发展中占据主体地位,主要从事丝绸、当铺等贸易。本土商人实力较弱,主要从事药材和粮食贸易。会馆是客居异乡的商人进行社交的重要舞台,在经济活动中起到了重要的载体和媒介作用。

  20. External Qi of Yan Xin Qigong Inhibits Activation of Akt, Erk1/2 and NF-ĸB and Induces Cell Cycle Arrest and Apoptosis in Colorectal Cancer Cells

    Directory of Open Access Journals (Sweden)

    Xin Yan

    2013-01-01

    Full Text Available Background/Aims: Colorectal cancer (CRC is the second leading cause of cancer death in the Western countries. Novel approaches of treatment are needed for CRC. The purpose of the present study was to investigate cytotoxic effect of external Qi of Yan Xin Qigong (YXQ-EQ on human colorectal cancer cells. Methods: The effect of YXQ-EQ on viability, cell cycle progression and apoptosis in colorectal cancer HT-29 cells was investigated. Phosphorylation of Akt and Erk1/2, activation of NF-ĸB and the expression of proteins involved in regulation of cell cycle and apoptosis were examined by Western blot analysis. Results: YXQ-EQ markedly decreased viability and blocked colony formation of HT-29 cells. YXQ-EQ downregulated cyclin D1 expression and increased accumulation of cyclin-dependent kinase inhibitors p21Cip1 and p27Kip1, resulting in G1 cell cycle arrest. YXQ-EQ induced apoptosis in HT-29 cells in association with decreased expression of antiapoptotic proteins Bcl-xL, XIAP, survivin and Mcl-1 and elevated expression of proapoptotic protein Bax. YXQ-EQ significantly repressed phosphorylation of Akt and Erk1/2 and NF-ĸB activation in HT-29 cells, suggesting that YXQ-EQ may exert cytotoxic effect through regulating signaling pathways critical for cell proliferation and survival. Furthermore, YXQ-EQ treated PBS and an YXQ-EQ treated plant extract induced apoptosis in HT-29 cells. Conclusion: These findings show that YXQ-EQ has potent cytotoxic effect on HT-29 cells and suggest that YXQ-EQ could be potentially used for colorectal cancer treatment either directly or indirectly via carriers.

  1. Optimization Design of Xin Jiang QiTai 2×350MW Power Plant Control System%新疆奇台2×350MW电厂控制系统设计优化

    Institute of Scientific and Technical Information of China (English)

    朱孟强

    2016-01-01

    Set in control system of QiTai 2×350MW power plant, this paper introduce the network structure, hardware configuration and control range of the main and BOP system integrated DCS control system. In order to ensure the safety and stability of control system, the unit DCS network and BOP network divided into two separate network. The whole plant DCS main and BOP system integrated achieve a seamless connection in the hardware, to avoid the DCS interface with variety of hardware device, improve the reliability of the control system ,reducing the maintenance and spare parts, and greatly reducing the maintenance cost.%以新疆奇台2×350MW工程全厂控制系统为背景,介绍DCS主辅机一体化控制系统的结构、硬件配置及控制范围。主机DCS网络与全厂辅助控制网络分为两个独立的网络,确保系统的稳定性和安全性。全厂DCS主辅机一体化方式在硬件上实现了无缝连接,避免了DCS与多种硬件设备的接口,提高了控制系统的可靠性,减少了备品备件种类和控制系统维护工作量,大大节约了维护成本。

  2. 特发性室早气阴两虚证患者自主神经功能的变化%Changes of Autonomic Nerve Function in Premature Ventricular Contraction Beats Patients with Deficiency of both Qi and Yin

    Institute of Scientific and Technical Information of China (English)

    阮小芬; 王肖龙; 张一乐; 徐燕; 龚菊芬; 吴昉怡

    2013-01-01

    目的 探讨气阴两虚证室早患者自主神经功能变化的特点.方法 与30例健康对照组相比较,分析41例室早患者自主神经功能各项指标变化,及室早、中医证候与自主神经功能的相关性.结果 室早组患者的SDANN、rMSSD、PNN50显著降低,室早患者中医证候积分与rMSSD、PNN50显著负相关.结论 气阴两虚证室早患者存在迷走神经功能显著降低及交感神经功能亢进,室早临床症状产生与迷走神经功能低下相关.%Objective: To observe the characteristics of autonomic nerve function in premature ventricular contraction beats(PVC) patients. Methods: Compared with 30 healthy controls,the autonomic nervous function of 41 cases PVC patients and the relationship between ventricular premature, the clinical symptoms and autonomic nervous function were analysed. Results: SDANN, rMSSD, and PNN50 were significantly lower in patients with PVC. TCM syndrome and rMSSD, PNN50 was significantly negative correlation. Conclusions: The vagus nerve function are decreased and the sympathetic nerve functionin is hyperthyroidism in PVC patients of both deficiency qi and Yin. clinical symptoms have associated with the vagus nerve function.

  3. Desire World and Game Psychology of Qi -style Fu Works in the Han Dynasty%汉代七体赋的欲望世界与游戏心态

    Institute of Scientific and Technical Information of China (English)

    冯小禄; 张欢

    2012-01-01

    对包含《七发》在内的汉代七体赋,我们从不断模拟翻写的文学事实出发,讨论其创作动机和由此彰显出来的汉人欲望世界和游戏心态。他们把本是人类最基本的物质需要和现实追求推衍到极致,对美食、美色和宫室娱乐作了帝王般的穷奢极欲描绘。而七事内容的随意安排和被劝主人的被动处理,又可见汉人的游戏为文心理,以及对世俗享受的沉溺、向往和与不同时期的现政权所发生的离合态势。%Qi - style Fu works in the Han dynasty, including Qifa (七发, Seven Ways to Enlighten the Prince on His Behaviors) were continuously imitated in that period of time. From this fact, the authors discussed the crea- tion motivation and further the desire world and game psychology of Han people. In this type of Fu works, the authors advanced the most essential living demands, such exaggerated peak, as if they had been the Kings. From as fine food, woman' s beauty and palace recreation to an and the passive reaction of the leading actor, we can see worldly desires and the pendulous situation between the the text arrangement about the content of seven programs recreational writing psychology, the wistful longing for scholars and the imperial court in two Han Dynasties.

  4. 齐地兵家文化视角下的现代企业团队管理%Reaseach on the Mordern Enterprise Team Management in the Perspective of Qi Military Strategist Culture

    Institute of Scientific and Technical Information of China (English)

    李文明

    2012-01-01

    企业团队管理的研究由来已久,研究成果日渐丰富,但是基于传统文化视角的团队整合研究还处于探索阶段,适用的研究成果还不多。鉴于此,从齐地兵家文化的视角研究现代企业高绩效团队的构建理念与方法,力争从孙子兵法、六韬思想以及管仲的军事管理学说中梳理出可以适用于现代企业团队管理发展的指导思想与管理技巧,是一种有益的尝试。这种研究,对于丰富现代企业团队管理的理论与方法,指导现代企业创建高绩效的团队具有重要的现实意义。%Enterprise team management for a long time, research is increasingly abundant, but still at the exploratory stage concerning team integration of traditional culture - based perspective, and the applicable finding is not much. For this reason, the article introduces the concept and method of constructing modern en- terprise high -performance team from Qi military strategist culture perspective, and strives for getting guiding ideology and management skills that can be applied in the modern enterprise team management from Sun Tzu's "The Art of War", idea of "Six Volumes of Stratagem and Tactic" and Guan Zhong's military management the- ory. The study attempting to enrich the modern enterprise team management theory and methods and guide the modern enterprise to build high -performance team has important practical significance.

  5. 肝郁气滞证视神经炎大鼠模型的建立%The establishment of the rat model with liver qi stagnation syndrom of optic neuritis

    Institute of Scientific and Technical Information of China (English)

    高芳; 柴金苗

    2015-01-01

    目的:建立肝郁气滞证视神经炎大鼠模型。方法:利用EAE动物模型和肝郁证大鼠模型的组合方法,对40只Wistar大鼠进行造模,观察大鼠的行为学变化、糖水偏好值、血浆促肾上腺皮质激素(ACTH)水平、肝脏及视网膜的病理改变。结果:与正常组比较,模型组的EAE神经功能评分、ACTH水平增加,1%蔗糖水摄入量降低(P<0.05,P<0.01)。结论:利用EAE动物模型结合肝郁证大鼠模型的方法,通过各指标显示,肝郁气滞证视神经炎组动物模型具备了视神经炎病肝郁气滞证的特点,与正常组相比模型制备成功。%Objective:To built the rat models with liver qi stagnation syndrom of optic neuritis. Method:Models were built through injection of immune antigen,chronic stimulation and solitary feeding. Then the behavioral changes,1%sucrose in-take,pathology changes of liver as well as retinal tissue were observed,and adrenocorticotropic hormone (ACTH)level in plasma was detected. Results:Compared with the normal group,the EAE score and ACTH concentration of rats in model group were increased,but the 1% sucrose intake was decreased (P<0.05,P<0.01). Conclusion:This modeling method is feasible.

  6. HPLC Determination of logganin in Qi Chrysanthemum rehmanrha pill(concentrated pill)%HPLC法测定杞菊地黄丸(浓缩丸)中马钱苷的含量

    Institute of Scientific and Technical Information of China (English)

    郑风敏; 刘会艳

    2015-01-01

    Objective:To estabilish a method for the determination of of loganin in Qi Chrysanthemum rehmanrha pill (concentrated pill) Method:HPLC C18(4.6mm×250mm,5μm) ,column was used with methanol—acetonitrile—phosphate(0.1%)(5:9:86). The flow rate was 1.0mL/min. The detection wave length was 236nm. The column temperature was at 30℃, and the inject volume was 10μL. Results:The calibration curves showed good linearity in the range of 2μg~0.8416μg (loganin)(r=0.9998).The average recoveries were 99.0%,RSD were1.2%(n=6).Conclusion:This Method is simple, accurate, and could be adopted for the quality control of this durg .%目的:建立测定杞菊地黄丸(浓缩丸)中马钱苷的含量测定方法.方法:HPLC法;C18柱(4.6mm×250mm,5μm),流动相为甲醇-乙腈-0.1%磷酸溶液(5:9:86),流速为1.0mL/min;检测波长236nm;柱温30℃;进样量10μL. 结果:马钱苷的线性范围为2μg~0.8416μg,相关系数为0.9998;平均加样回收率为99.0%,RSD为1.2%(n=6). 结论:该法简单,准确度高,重复性好,可用于控制杞菊地黄丸(浓缩丸)的质量.

  7. [Simultaneous determination and quantitation of anthraquinones, lignans and flavonoids in Xiao-Cheng-Qi Tang, Hou-Po-San-Wu Tang and Hou-Po-Da-Huang Tang by HPLC].

    Science.gov (United States)

    Chen, Li; Li, Tao; Wang, Yan-li; Dong, Yu; Zhuang, Shuai-xing; Wang, Dun-fang; Yang, Wei-peng

    2015-07-01

    A simple and selective HPLC method for simultaneous determination and quantification of anthraquinones, lignans and flavonoids in Xiao-Cheng-Qi Tang (XCQT), Hou-Po-San-Wu Tang (HPSWT) and Hou-Po-Da-Huang Tang (HPDHT) was developed and validated. An Agilent Zorbax SB-C 18 (4.6 mm x 250 mm, 5 µm) column with the mobile phase of acetonitrile and 0.5% acetic acid aqueous solution in gradient elution mode was used. The flow rate was 1.0 mL · min(-1) at 30 °C, and injection volume was 10 µL. The detection wavelength was set at 254 nm and 294 nm simultaneously for the quantitative analysis. The current HPLC assay was validated for linearity, intra-day and inter-day precisions, accuracy, recovery and stability. The method was applied to the content comparison of the gallic acid, cinnamic acid, sennoside A, sennoside B, rhein, emodin, aloe-emodin, chrysophanol, physcion, magnolol, honokiol, narirutin, naringin, hesperidin, neohesperidin, hesperetin, naringenin and nobiletin in XCQT, HPSWT and HPDHT. The good linear equations of eighteen constituents were obtained within the investigated ranges (r > 0.998). The recovery of the method was 94.28%-99.89% and the precision was less than 5%. The sample was stable within 16 h. There were some differences between the contents of anthraquinones, lignans and flavonoids in analogous formulae about XCQT. XCQT contained the greatest abundance of anthraquinones and flavonoid, HPSWT contained the greatest abundance lignans. In conclusion, the methods are simple, low-cost, precise, accurate and reliable for the determination of eighteen constituents in analogous formulae about XCQT, and these results provide methodological support for its quality control.

  8. 益气健脾法用于危重症患者营养障碍的临床研究%The method of replenishing Qi to invigorate spleen treats the patients of severe cases with malnutrition

    Institute of Scientific and Technical Information of China (English)

    张珍方; 朱晓岩; 侯荣耀; 王玉春; 许宏伟; 张正寿; 唐明; 吴军; 李倩

    2013-01-01

    Objective To explore the method of replenishing qi to invigorate spleen combined with enteral nutrition therapy in the treatment of patients with severe cases and malnutrition.Methods Reviewed 100cases of critically patients with severe cases who came from the intensive care unit(ICU) of Qingdao Hiser Hospital from January of 2010 to November of 2011.According to the unified criteria of patients selection,we randomly divided them into two groups,namely,a control group,who received enteral nutrition only,and an experiment group,who received enteral nutrition combined with the traditional Chinese medicine to replenish qi and invigorate spleen.Detecting the nutritional markers as follows in two groups on the first day before the nourishment therapy,on the fifth day and the tenth day after treatment,which were Total protein(TP),Albumin (ALB),Preabumin (PA),Hemoglobin (HB).Results No matter five days or ten days after the treatment,the nutrition markers such as PA,TP and ALB of the control group had the tendency to increase,but no statistically significance (P>0.05).The experiment group had improved such markers as ALB and TP after five days [(58.20±3.62) g,(30.42± 3.06) g] and ten days [(65.04± 3.74) g,(34.26± 3.07) g] significantly(P<0.05).The experiment group had improved significantly such markers as PA after ten days (268.50±54.3) g,(P<0.05).Conclusion We consider using enteral nutrition only is not clear to improve malnutrition,however,using the Chinese medicine of replenishing qi to invigorate spleen therapy combined with enteral nutrition can improve malnutrition.%目的 观察益气健脾法(四君子汤)联合肠内营养剂治疗危重症患者营养障碍的疗效.方法 回顾性分析2010年1月至2011年11月青岛市海慈医疗集团重症医学科收治的100例危重症患者,按病例尾号随机分为两组各50例.对照组采用能全力以肠内营养泵匀速滴注治疗,试验组在对照组治疗基础上加用四君子汤治疗.

  9. 眩晕灵治疗气虚血瘀型后循环缺血性眩晕的临床观察%Xuanyunling in the treatment of ischemic vertigo due to Qi deficiency and blood stasis syndrome

    Institute of Scientific and Technical Information of China (English)

    张选国

    2016-01-01

    目的:观察眩晕灵治疗气虚血瘀型后循环缺血性眩晕的临床疗效。方法:将入选的90例病例随机分为对照组、治疗组和西药组,每组均30例,对照组口服阿司匹林肠溶片,100 m g/d ,并予灯盏细辛注射液静滴,治疗组在对照组基础上服用眩晕灵(黄芪、当归、川芎、赤芍、天麻、白术、半夏、川牛膝等),西药组对照组基础上服用盐酸氟桂利嗪胶囊,每次1粒,1 d1次。结果:治疗前3组之间西医体征量表积分、中医症状分级量化积分、Barthel Index积分、眼震电图积分之间比较均无差异。治疗后,对照组西医体征量表积分、中医症状分级量化积分、Barthel Index积分、眼震电图积分均值较治疗前好转,但无差异(P>0.05)。治疗组、西药组治疗后西医体征量表积分、中医症状分级量化积分、Barthel Index积分、眼震电图积分均值较治疗前好转,有差异(P<0.05)。治疗组、西药组治疗后上述各指标较对照组治疗后有差异(P<0.05),治疗组、西药组治疗后各指标之间无差异(P>0.05)。结论:本方法治疗本病安全、有效。%Objective:To evaluate Xuanyunling in the treatment of Qi deficiency and blood stasis of the effectiveness and safety of posterior circulation ischemia vertigo .Methods:According to the (random) sequence random grouping principle the diagnostic criteria ,included 90 patients with Qi deficiency and iblood stasis type ,excluded stand‐ard ,excluded standard ,Chinese Constitution selected posterior circulationischemic vertigo patients ,randomly divided into control group of 30 cases ,30 cases in the treatment group ,the western medicine group of 30 cases .All selected patients taking preventive dose Aspirin Enteric‐coated tablets 100mg/d ,and salvia injection intravenous drip ,on the basis of the treatment group taking vertigo Ling ,5 capsules each time ,3 times a day

  10. 肺癌痰湿蕴肺证、气阴两虚证患者呼出气冷凝液的代谢组学研究%Metabonomic Study on Exhaled Breath Condensate(EBC)of Lung Cancer with Syndrome of Turbid Phlegm Obstructing Lung and Syndrome of Deficiency of Both Qi and Yin

    Institute of Scientific and Technical Information of China (English)

    周贤梅; 尤寅骏

    2012-01-01

    目的:通过分析肺癌痰湿蕴肺证和气阴两虚证患者的呼出气冷凝液(EBC)代谢产物,探讨肺癌中医证型科学客观化的可行性.方法:选择肺癌痰湿蕴肺证患者(痰湿蕴肺组)21例、气阴两虚证患者(气阴两虚组)21例及健康志愿者(健康对照组)20例,采集受试者EBC,利用气相色谱-质谱(GC-MS)技术分析EBC代谢产物.结果:痰湿蕴肺组和气阴两虚组均能够与健康对照组区分,发现9种潜在的肿瘤标志物,其中3种为痰湿蕴肺组和气阴两虚组特有化合物,6种为痰湿蕴肺组和气阴两虚组与对照组共有化合物;痰湿蕴肺组能够与气阴两虚组区分,3-氨基-2-苯甲酰基-4,5,6,7-四氢苯并[b]噻吩为痰湿蕴肺组特有化合物,1-(苯基磺酰基)吡咯为气阴两虚组特有化合物.结论:EBC的代谢组学研究方法具有用于肺癌的诊断及肺癌不同中医证型的临床客观化指标的研究的可能性.%Objective: To analyze the exhaled breath condensate ( EBC) of the patients with lung cancer of syndrome of turbid phlegm obstructing lung and syndrome of deficiency of both Qi and Yin. To explore the results of metabonomics and connotation of modem science on syndrome of turbid phlegm obstructing lung and syndrome of deficiency of both Qi and Yin in lung cancer,and try to discover biomarkers. Methods: The study included 21 patients with lung cancer of syndrome of turbid phlegm obstructing lung,21 patients with lung eancer of syndrome of deficiency of both Qi and Yin,and 20 healthy volunteers. After collection of EBC , the EBC samples were analyzed with GC - MS. Results ;The patients of syndrome of turbid phlegm obstructing lung and syndrome of deficiency of both Qi and Yin were clearly distinguished from healthy persons. 9 potential tumor biomarkers were discovered ,including 3 molecules existed in most patient group samples,and 6 in all groups, while the-quantities of the 6 molecules in patient groups were significantly

  11. Efficacy of Gualouniebaibanxia Decoction and Danshen Decoction in Treatment of Phlegm and Blood Stasis of Obstruction of Qi in the Chest%瓜蒌薤白半夏汤配合丹参饮对痰瘀互阻型胸痹的治疗效果观察

    Institute of Scientific and Technical Information of China (English)

    张春光

    2015-01-01

    ObjectiveTo investigate the clinical therapeutic effect of gualouxiebaibanxia decoction combined with danshen decoction in treatment of phlegm and blood stasis of obstruction of qi in the chest.Methods40 cases of phlegm stasis mutual resistance type of obstruction of qi in the chest patients were divided into study group(gualou xiebai banxia decoction combined with danshen decoction)and control group(routine),comparative analysis the clinical efficacy of the two groups of patients. ResultsThe total effective rate of the study group and the improvement rate of ECG were significantly higher than those in the control group,the difference between the two groups was significant(P<0.05).Conclusion Gualouxiebaibanxia decoction combined with danshen decoction on phlegm and blood stasis obstruction of qi in the chest has a good clinical effect.%目的:探讨瓜蒌薤白半夏汤配合丹参饮对痰瘀互阻型胸痹的临床治疗效果。方法将40例痰瘀互阻型胸痹患者分为研究组(瓜蒌薤白半夏汤联合丹参饮)和对照组(常规西医),对比两组临床疗效。结果研究组治疗总有效率、心电图改善率高于对照组,二者差异有统计学意义(P<0.05)。结论瓜蒌薤白半夏汤配合丹参饮对痰瘀互阻型胸痹有较好临床效果。

  12. 从经典选择到不同思路之辩——简论朱子理气观的形成%A Defense for Classic Selection and Different Thinkings——A Concise Discussion on the Formation of Zhu Xi's Theory of Qi

    Institute of Scientific and Technical Information of China (English)

    丁为祥

    2012-01-01

    理气关系是朱子哲学的核心,也是宋明理学的核心论题。但朱子理气观的形成却是一个颇为复杂的过程,也几乎伴随了朱子的一生。大体说来,这一过程是从受教于李延平起始的,而以对《中庸》与《大学》之不同经典的选择展开的;至于从"中和"旧说到"中和"新说,则表明朱子宇宙论视野的初步形成;到了与张栻的"仁说"之辩,则既标志着其思想谱系的奠基,同时也代表着其理气双重视角的定型。%The relationship between ration and Qi is the core of Zhu Xi's philosophy and also the key subject of Neo-Confucianism in the Song and the Ming Dynasty.However,Zhu Xi experienced a rather complicated process to form his theory of ration and Qi,which cost nearly the whole of his life.Roughly speaking,this process started from Li Yanping's instructions he received,and went on by selecting from different classics of The Great Learning and The Golden Mean of the Confucian School.The transition from the old vision to the new vision of "neutralization" indicated the preliminary formation of Zhu's vision of cosmology.His debate with Zhang Shi on "the theory of benevolence" signaled both a foundation laid for the system of his theory and the finalization of his double perspective of ration and Qi.

  13. Benefiting Qi and moistening lung for arresting cough combined with Western medicine in the treatment of 56 children with bronchial asthma in remission stage%益气润肺止咳法结合西药治疗儿童支气管哮喘缓解期56例疗效观察

    Institute of Scientific and Technical Information of China (English)

    陈定锋

    2012-01-01

    Objective To observe the clinical effect ofarresting cough therapy by benefiting Qi and moistening lung combined with Western medicine in the treatment of bronchial asthma in children. Methods 56 children of bronchial asthma were randomly divided into two groups. The study group (n=30) received arresting cough therapy by benefiting Qi and moistening lung combined with routine Western medicine therapy. The control group (n=26) were treated with conventional treatment of Western medicine, for two weeks. Results The effective rate was 95% in the study group and 80% in the control group, with statistically significant difference between the two groups (P<0.05). Conclusion Benefiting Qi and moistening lung for arresting cough combined with Western medicine is quite effective for treating bronchial asthma.%目的 观察益气润肺止咳法结合西药治疗支气管哮喘的临床疗效.方法 将56例支气管哮喘患者随机分为两组.治疗组30例,予益润肺止咳法结合西药常规治疗;对照组26例,予西药常规治疗,疗程为两周.结果 治疗组有效率为95%,对照组为80%,两组总有效率比较,差异有统计学意义(P<0.05).结论 益气润肺止咳法结合西药治疗支气管哮喘疗效确切.

  14. Clinical observation on the hypnotic therapy combined with Xiaoyao pill in the treatment of qi stagnation type of liver depression%催眠疗法联合逍遥丸治疗肝郁气滞型郁证的临床观察

    Institute of Scientific and Technical Information of China (English)

    张焕芝; 朱向东; 张静霞

    2015-01-01

    Objective:To investigate the clinical efficacy of hypnotic therapy combined with Xiaoyao pill in the treatment of qi stagnation type of liver depression.Methods:60 patients with qi stagnation type of liver depression were randomly divided into two groups according to medical order,with 30 cases in each group.Patients in the treatment group were given the hypnotic treatment combination with Xiaoyao pill,while the control group were treated with Xiaoyao pill.Results:The effective rate of the treatment group was 83.33%,while the control group was 60%,and the difference was statistically significant between the two groups(P<0.05).Conclusion:The clinical efficacy of hypnotherapy combined with Xiaoyao pill has significantly effect in the treatment of qi stagnation type of liver depression.%目的:探讨催眠疗法联合逍遥丸治疗肝郁气滞型郁证的临床疗效。方法:将60例郁证(肝郁气滞型)患者按就诊顺序随机分为两组各30例。治疗组给予催眠疗法联合逍遥丸治疗,对照组给予逍遥丸口服治疗。结果:治疗组有效率83.33%,对照组有效率60.00%,差异有统计学意义(P<0.05)。结论:催眠疗法联合逍遥丸治疗肝郁气滞型郁证的疗效显著。

  15. "曾"、"烝"考论——兼论远古蒸食工艺及先民对"气"的哲学思辨%A Textual Research into "Zeng" and"Zheng":on Ancient Technology in Steamed Food and Philosophical Thoughts of the Ancient s on"Qi"

    Institute of Scientific and Technical Information of China (English)

    马健鹰; 嵇娟娟

    2015-01-01

    蒸始于"曾". "曾"字为远古先民所造蒸器之象形,在以甑熟食的过程中,先民又感悟出蒸气腾升、以气化熟的气化形式,其古汉字的初形就是"烝".先民在蒸食工艺的实践中认知了蒸气的神奇作用,并引发了对"气"从物象渐渐地转入精神层面的思考. 这可从两个方面得以体现,一是"曾"、" 烝"、"蒸"等字的本义转化;二是先哲对"气"的哲学思辨. 先民蒸食烹饪所产生的气成为后世哲学意义上的"气"之概念的源头.%Chinese character"蒸"——steaming, originates from"曾", a pictograph representing the steam-ing utensil made by the ancients.When cooking with "甑"——an earthen utensil used for steaming rice by our ancestors, they realized vaporized steam cooked food and created the ancient Chinese pictogram "烝", meaning "to rise as steam".The realization of the magic function of steam in cooking practice led the ancients gradually to speculate on "Qi"not from its physical image any more but from its spiritual dimensions.Two manifestations for the above inference:meaning shifts of Chinese characters as"曾","烝", and"蒸";phil-osophical thoughts of the great thinkers on "Qi" ( the vital energy ) .Qi——steam produced when ancients cooked by steaming became the origin of"Qi" in late philosophy.

  16. Qi Jiguang Look at the Development of Wushu Practical Ideas and Countermeasures From the "Ji Xiao Xin Shu"%从《纪效新书》看戚继光发展武术实用性思想与对策

    Institute of Scientific and Technical Information of China (English)

    马斌; 马兰

    2015-01-01

    Qi Jiguang is a heavyweight Chinese military history,life Ge immediately,exploits numerous,his"Ji Xiao Xin Shu"system shows the genius of his military thought,to have the time to the theory of sublimation,in Chinese Wushu history has left a heavy color ink pen.This article uses the literature material law practical martial arts guide of Qi Jiguang's thinking of doing the objective description,illustrates the improved attention weapon is play Wushu practical preconditions,and describe the embodiment of practical Wushu thought with from the technical aspect.When we now face a variety of debate about the use of martial arts,martial arts have a look back of Qi Jiguang thought,perhaps it will get more enlightenment.Therefore,summing up martial arts guide thought of Qi Jiguang,refining the development of Wushu viewpoint of far-reaching significance in our research of wushu.%戚继光是中国军事史中的一个重量级人物,一生持戈马上,战功无数,他所著的《纪效新书》系统的展现了他天才的军事思想,达到了有时间到理论的升华,在中国武术史上留下了浓墨重彩的一笔.该文采用文献资料法对戚继光的实用性的武术指导思想做了客观论述,阐明了重视兵器的改良是发挥武术实用性的先决条件,并从技术方面详细描述武术实用性思想的体现.当我们现在面临关于武术使用性的种种争论时,回头看看戚继光的武术思想,或许从中会得到更多启迪.因此总结戚继光的武术指导思想,提炼其发展武术的观点对于我们今天研究武术具有深远意义.

  17. Study on the Protection of Historical Cultural District in City Renewal Process-- Taking Qi Ning Street Xiuning County as an Example%城市更新过程中的历史文化街区保护研究--以休宁县齐宁街为例

    Institute of Scientific and Technical Information of China (English)

    钱坤

    2014-01-01

    This paper, aiming at the misconceptions and ex- isting problems about the development activities of historic district, taking the protection of historical cultural district of Qi Ning street in Xiuning County as example, put forward some thoughts and countermeasures on the protection of the histo- rical block.%本文就浅议历史街区开发活动中的误区和存在问题,以休宁县齐宁街历史文化街区保护情况为例,对历史街区的保护对策方面提出了一些思考。

  18. 活血益气法对气滞血瘀证2型糖尿病大鼠治疗的实验研究%The Experiment Research on Qi Stasis Plus Blood Stasis Diabetic Rat Models with Active-blood Soup and yiqi-vein's Method

    Institute of Scientific and Technical Information of China (English)

    陈嘉斌; 柴可夫; 张副兴; 吕帅洁; 郑杨

    2011-01-01

    目的:研究活血益气法对于气滞血瘀证型2型糖尿病大鼠模型的治疗作用.方法:对大鼠用针刺激~[1]及高脂高糖饮食~[2]建立气滞血瘀证型.后给予大鼠日照并灌胃脂肪乳10日后尾静脉一次性注射四氧嘧啶(80m/kg)建立2型糖尿病模型.采用血府逐瘀汤加生黄芪怀山药进行治疗并检测指标.结果:通过血液流变学指标,血糖等客观指标分析,模型建立可靠,气滞血瘀证型2型糖尿病大鼠各指标明显好转.结论:使用针刺及高脂喂食建立模型可为将来2型糖尿病中医研究提供实验基础,活血益气法治疗气滞血瘀证2型糖尿病具有较好的疗效,但用药需谨慎配伍.%Objective: To study the effect on Qi stasis plus blood stasis diabetic rat models by Active - blood soup and yiqi - veins method. Methods:The Qi stasis plus blood stasis diabetic rat models were made by electroacupuncture stimulation and high - sugar - fat - diet. Then give them Fat Emulsion and sunlight for 10 days before injecting one - off Al-loxan monohydrate on the vein of tail. Give the treatment with Active - blood soup and yiqi - veins method and record the index. Results; According to the analysis of hemorheology indices and glucose objective index, it turns out that the models are reliable. The rats indexes improve. Conclusion Setting Qi stasis plus blood stasis diabetic rat models up will offer new experimental basis for the studies in the future. The treatment, Qi stasis plus blood stasis diabetic mellitus with Active -blood soup and yiqi -veins method,has good effectiveness,we should be careful with the traditional Medicine compatibility.

  19. [Efficacy of Chinese Herbs for Supplementing Qi and Activating Blood Circulation on Patients with Acute Coronary Syndrome and Type 2 Diabetes Mellitus after Percutaneous Coronary Intervention: a Clinical Observation].

    Science.gov (United States)

    Du, Jian-peng; Wang, Cheng-long; Wang, Pei-li; Wang, Shao-li; Gao, Zhu-ye; Zhang, Da-wu; Xu, Hao; Shi, Da-zhuo

    2015-05-01

    To observe the efficacy of Chinese herbs for supplementing qi and activating blood circulation (CHSQABC) on patients with acute coronary syndrome (ACS) and type 2 diabetes mellitus (DM) after successful percutaneous coronary intervention (PCI). In this ChiCTR-TRC-00000021, a total of 281 ACS patients complicated with type 2 DM after successful PCI were randomly assigned to the Western medicine treatment group (the control group, treated by routine Western medicine treatment) and the combined treatment group (the treatment group, treated by CHSQABC + routine Western medicine treatment). Patients in the combined treatment group took Xinyue Capsule (2 pills each time, 3 times per day) and Compound Chuanxiong Capsule (2 pills each time, 3 times per day for half a year and 1-year follow-ups). Primary endpoints covered incidence of death, nonfatal myocardial infarction (MI), ischemia-driven revascularization, and secondary endpoints included stroke, heart failure, and rehospitalization for ACS. At the same time scores for blood stasis syndrome (BSS) and the incidence of angina pectoris were evaluated before treatment, at month 1, 3, 6, 9, and 12 after treatment. The incidence of ischemia-driven revascularization was obviously less in the treatment group than in the control group (P 0.05). Four patients readmitted to hospital in the treatment group, while 12 patients readmitted. There existed obvious tendency in the treatment group, but with no statistical difference when compared with that in the control group (P > 0.05). The incidence of angina was significantly lower in the treatment group at month 6, 9, and 12 than that at month 1 , but it was lower in the control group at 9 months (P < 0.05). The incidence of angina was 15. 4% in the treatment group, obviously lower than that in the control group (26.2%, P < 0.05). Compared with before treatment, scores for BSS were obviously lowered in the treatment group at 1, 3, 6, 9, and 12 months of treatment and in the control

  20. 疏肝理气消瘿法治疗早期桥本甲状腺炎的临床研究%Clinical research of soothing the liver regulating qi and xiaoying method on chronic early hashimoto thyroiditis

    Institute of Scientific and Technical Information of China (English)

    吴晓青; 张有涛; 郝立鹏; 秦泗关; 阳其娟; 管雯雯; 石超

    2012-01-01

    [Objective] To evaluate the clinical curative effect of the method of soothing the liver, regulating qi and xiaoying(SLRQXYM) on chronic early hashimoto thyroiditis. [Methods] The 60 patients with chronic early hashimoto thyroiditis were randomly divided into SLRLXYM-treated group(n=30)and control group(n=30). The patients of the SLRLXYM-treated group received treatment of SLRLXYM combined with levothyroxine while the others in the control group received treatment of levothyroxine and prednisone for 12 weeks. The serum levels of thyroid hormones and the titres of serum antithyroglobulin antibody (anti-TG Ab) and antithyroid microsomal antibody (anti-TM Ab)were all examined before and after treatment. The total response rates of the two groups were evaluated after treatment of 12 weeks. [Results] The total effective rate of the SLRQXYM-treated group was 93.3%, while that of the control group had no obvious changes. There was significant difference between SLRQXYM-treated group and control group. [Conclusion] The SLRLXYM can shrink and soften the enlarged thyroid gland and thyroid nodules, improve the immune function of human body, alleviate thyroid autoimmune response , has good clinical effect.%[目的]观察疏肝理气消瘿法治疗早期桥本甲状腺炎的临床疗效.[方法]60例早期桥本甲状腺炎患者,随机分为疏肝理气消瘿法治疗组和对照组,每组30例.治疗12周后,检测两组患者甲状腺功能及血清抗甲状腺自身抗体滴度水平,并进行临床疗效评价.[结果]疏肝理气消瘿法治疗组总有效率93.3%,对照组未见明显变化,两组比较差异有统计学意义.[结论]疏肝理气消瘿法治疗早期桥本甲状腺炎,可以提高机体的免疫功能、减轻甲状腺的自身免疫反应,有利于控制病情发展,具有良好的临床疗效.

  1. Brief academic experience introduction of professor XIONG Man-qi in treatment of diabetes%熊曼琪教授治疗糖尿病学术经验述略

    Institute of Scientific and Technical Information of China (English)

    邓烨; 李赛美; 朱章志

    2012-01-01

    Chinese Medicine is a subject with its unique process of development and characteristics. It was promoted by academic thoughts and clinical experience accumulated famous Chinese medicine doctors in the past dynasties, in every aspect of basic theory, clinic, education and research. Professor XIONG Man-qi is one of the famous experts on treatise of febrile disease in the South of the five ridges, as well as an educator and clinician. She learned from the famous Chinese medicine expert professor LIU Chi-xuan and keep working on teaching, studing, and clinical application of Shanghan Urn for more than 30 years. She has accumulated rich experience and fonded original academic thoughts especially in diagnosis and treatment of diabetes and its complications. Sanhuang Jiangtang Pian, Sanhuang Tang Shen an Pian, Qitao Pian which were originated from classic prescriptions like Taohe Chengqi Decoction, Huangqi Guizhi Wuwu Decoction, showing great clinical effect and had been deeply studied both on theory and experiment, which became precious treasure in Chinese medicine of the south of the five ridges.%熊曼琪教授是我国当代著名的伤寒学家.她从师于著名中医学家刘赤选教授,从事《伤寒论》教学、科研以及内科临床工作40余年,形成了丰富而独到的临床经验和学术思想.尤其在糖尿病及其并发症的诊治上,根据经方中的桃核承气汤、黄芪桂枝五物汤所创的三黄降糖片、三黄糖肾安片、芪桃片等专方专药在临床取得良效,理论和实验研究也丰富而深入,是当代岭南中医学的宝贵财富.

  2. Clinical efficacy of the treatment of liver cirrhosis ascites by the method of Supplementing Qi and warming Yang%益气温阳法治疗肝硬化腹水的临床疗效分析

    Institute of Scientific and Technical Information of China (English)

    王庆成

    2015-01-01

    Objective:To analyze the clinical effect of the treatment of liver cirrhosis ascites by the method of Supplementing Qi and warming yang .Methods 38 pa-tients with liver cirrhosis ascites were selected as the research object ,76 cases treated with conventional western medicine as the control group ,cases treated by conven-tional western medicine treatment,the observation group was treated with conventional western medicine treatment,38 cases treated by western medicine treatment,and the clinical effect of the two groups were statistically compared .Results The effective rate of the observation group was 73.68%,the difference was statistically significant (P<0.05).Conclusion The clinical effect of the treatment of liver cirrhosis with ascites in the treatment of conventional western medicine is significant ,and it is worth to be popularized.%目的 分析益气温阳法治疗肝硬化腹水的临床效果. 方法 选取2013年2月——2014年2月期间收治的肝硬化腹水患者76例作为研究对象,按治疗方法的不同,将行常规西医治疗的38例患者作为对照组,将行常规西医治疗联合益气温阳汤治疗的38 例患者作为观察组,治疗结束后,对两组患者的临床效果进行统计对比. 结果 观察组有效率为94 .74%,对照组有效率为73 .68%,差异有统计学意义( P<0 .05 );观察组腹水消退时间及住院费用均优于较对照组,差异有统计学意义(P<0.05). 结论 肝硬化腹水在常规西医治疗基础上联合益气温阳法治疗的临床效果显著,改善患者的症状,值得临床推广应用.

  3. Measurements of VOC fluxes by dynamic plant and soil chambers in wheat and maize crop near Paris with a PTR-Qi-TOF-MS: Quantification and response to environmental and physiological drivers.

    Science.gov (United States)

    Gonzaga-Gomez, Lais; Boissard, Christophe; Ciuraru, Raluca; Lafouge, Florence; Zurfluh, Olivier; Buysse, Pauline; Decuq, Céline; Fanucci, Olivier; Gueudet, Jean-Christophe; Gros, Valérie; Sarda, Roland; Zannoni, Nora; Loubet, Benjamin

    2017-04-01

    Volatile organic compounds (VOC) play an important role in the chemistry of the atmosphere as precursors of secondary pollutants such as ozone and organic aerosols. A large variety of VOC are exchanged between plants (BVOC) and the atmosphere. Their fluxes are strongly dependent on environmental factors (temperature, light, biotic and abiotic stress) and vary greatly among plant species. Only few studies focused on BVOC emissions by agricultural plants and were mostly carried in North America. However, agricultural lands occupy 51% of the total country area in France, with wheat being one of the most important crop. We used a PTR-Qi-TOF-MS (national instrument within the ANAEE-France framework) and dynamic chambers to measure BVOC emissions from plant and soil compartments of a wheat and a maize crop near Paris (FR-GRI ICOS site). More than 700 masses were detected thanks to the resolution and sensitivity of this new instrument. We analyze the emission response to light, temperature and stomatal aperture in order to explain the mechanisms of BVOC exchanges by wheat plants. We investigate the emission differences between soil and plant compartment, and between wheat and maize crops. Acetone (m/z 59.049) was the predominant volatile compound in the emissions from wheat. Both methanol (m/z 33.033) and acetaldehyde (m/z 45.033) were also quite abundantly emitted but were less than half the acetone emissions. Other masses detected in relative importance in this study were m/z 63.026 (possible DMS), m/z 93.033 (not identified), m/z 69.069 (isoprene), m/z 57.069 (not identified), m/z 83.085 (possible green leaf volatiles), m/z 73.064 (methyl ethyl ketone). Their emissions were around 7 times smaller than the emissions of acetone. On the other hand we observed a deposition for, mainly, m/z 75.044 (hydroxyacetone) and m/z 61.028 (acetic acid). Methanol presented both positive and negative fluxes witch could indicate either emission or absorption of this compound by the

  4. Shen-Qi-Jie-Yu-Fang has antidepressant effects in a rodent model of postpartum depression by regulating the immune organs and subsets of T lymphocytes

    Directory of Open Access Journals (Sweden)

    Qu M

    2015-06-01

    Full Text Available Miao Qu,1 Qisheng Tang,1 Xiaoli Li,1 Ruizhen Zhao,1 Jingya Li,1 Hong Xu,2 Yushan Gao,2 Yingqiu Mao31Third Affiliated Hospital, 2School of Basic Medical Sciences, 3Center of Scientific Research, Beijing University of Chinese Medicine, Beijing, People’s Republic of China Background: Shen-Qi-Jie-Yu-Fang (SJ Fang is a herbal preparation used in traditional Chinese medicine, and is a potentially important new therapeutic agent in postpartum depression (PPD. Previously, we have elucidated the effects of SJ Fang on hormone receptors and monoamine neurotransmitters involved in the hypothalamic-pituitary-adrenal and hypothalamic-pituitary-gonadal axes in PPD rats. However, the immune-modulating effects of SJ Fang in PPD are still unknown. In this study, we explored the effects of SJ Fang on the immune organs and subsets of T lymphocytes in PPD rats.Methods: PPD was created in Sprague-Dawley rats by inducing hormone-simulated pregnancy followed by hormone withdrawal. After hormone withdrawal, the PPD rats were then treated with fluoxetine at 1, 2, and 4 weeks, and the SJ Fang rats were also treated at 1, 2, and 4 weeks. Depressive behavior in the rats was evaluated by the forced swim test, sucrose consumption test, and open field test. The thymus index and spleen index were calculated. Hematoxylin-eosin staining was used to identify pathological features in the thymus and spleen. CD3, CD4, and CD8 lymphocyte subsets were analyzed by flow cytometry.Results: Both fluoxetine and SJ Fang increased immobility time, sucrose consumption, an horizontal and vertical movements. After 4 weeks of treatment with fluoxetine or SJ Fang, the thymus index and spleen index were significantly higher than at baseline, and the morphology of the thymus and spleen were returning to normal. Two weeks after hormone withdrawal, subsets of T lymphocytes indicated a shift from immune activation to immune suppression, which was reversed by 4 weeks of treatment with fluoxetine or SJ

  5. Resource Letter QI-1: Quantum Information

    Science.gov (United States)

    Strauch, Frederick W.

    2016-07-01

    This Resource Letter surveys the history and modern developments in the field of quantum information. It is written to guide advanced undergraduates, beginning graduate students, and other new researchers to the theoretical and experimental aspects of this field. The topics covered include quantum states and processes, quantum coding and cryptography, quantum computation, the experimental implementation of quantum information processing, and the role of quantum information in the fundamental properties and foundations of physical theories.

  6. A winning game plan for QI.

    Science.gov (United States)

    Boyle, R L; Shaw, J G; Stewart, D

    1994-01-01

    Authors Robert L. Boyle, Jr., M.P.H., FACMPE, James G. Shaw, M.B.A., and Diane Stewart describe how to put a quality improvement program into practice by identifying key internal processes, selecting an improvement program, identifying what to improve and developing a review method. They also present results from the first year of their quality improvement process.

  7. The method of replenishing qi to invigorate spleen for treatment of senior patients with severe malnutrition%益气健脾法对重症老年患者营养不良的影响

    Institute of Scientific and Technical Information of China (English)

    朱晓岩; 侯荣耀; 许宏伟; 王玉春; 张正寿; 唐明; 吴军; 李倩

    2013-01-01

    Objective To explore the efficacy and safety of the method of replenishing qi to invigorate spleen combined with enteral nutrition therapy for treatment of senior patients with severe malnutrition. Methods A prospective randomized controlled study was conducted. There were 100 senior cases of critically severe malnutrition who came to the intensive care unit(ICU)of Qingdao Hiser Hospital from January 2010 to November 2011. According to the unified criteria of patients selection with the method of random number table,they were divided into control and experiment groups(each,50 cases). Both groups received enteral nutrition,and the experiment group additionally received Decoction of Four Mild Drugs(100 ml/d). The nutritional markers of blood total protein(TP),albumin (Alb),preabumin(PA)and hemoglobin(Hb)were detected in the two groups before and on the 5th and 10th day after treatment. The liver and renal functions were observed to estimate the therapeutic safety. Results On the 5th and 10th day after treatment,the nutrition markers of TP,Alb and PA in both groups had a tendency to increase. In the control group,there were no statistical significances in the comparisons of the above indexes before and after treatment(all P>0.05),while in the experiment group,TP and Alb on the 5th day after treatment had significant improvement and PA on the 10th day showed the same in the comparisons statistically(all P0.05). The liver and renal functions had no significant changes. Conclusion From the experiment,it is shown that using enteral nutrition only to improve malnutrition is not significant,however,the combination of Chinese medicine of replenishing qi to invigorate spleen therapy and enteral nutrition can improve the status of malnutrition in senior patients.%  目的探讨益气健脾中药四君子汤联合肠内营养剂治疗重症老年患者营养不良的有效性和安全性.方法采用前瞻性随机对照研究方法,将青岛市海慈医疗集团所

  8. 蠲痹胶囊对兔膝骨性关节炎模型的预防作用%The preventive effect of Chinese medicine with Replenishing kidney and invigorating Qi on rabbits osteoarthritis

    Institute of Scientific and Technical Information of China (English)

    袁普卫; 杨镇源; 史亚军; 周海哲; 朱超; 屈强

    2010-01-01

    目的 探讨补肾益气药预防家兔膝骨性关节炎的机制.方法 将72只4月龄健康日本长耳大白兔,随机分为空白组(A组)、模型组(B组)、中药高剂量组(C组)、中药中剂量组(D组)、中药小剂量组(E组)、盐酸氨基葡萄糖胶囊对照组(F组)6组各12只.除A组外,均采用石膏管形固定膝关节6周,制作兔膝骨性关节炎模型.在造模同时C、D、E、F组分别给予不同剂量中药、盐酸氨基葡萄糖胶囊灌胃4周.模型组给予用药组等容的生理盐水灌胃;空白组不灌胃.造模6周后抽取关节液,应用ELISA法测定关节液中肿瘤坏死因子(TNF-α)的变化.同时取关节软骨行大体及光镜检查.结果 组织学显示,C、D、E、F组膝关节软骨有不同程度的色泽变化,骨赘、骨囊肿形成,软骨关节面出现浅表性糜烂,部分标本软骨缺损深达软骨中层,出现软骨剥脱,但程度轻于B组.与A组比较,B组关节液中TNF-α含量明显升高(P<0.05),表明造模成功;C、D、E、F组的TNF-α含量均低于B组,差异有统计学意义(P均<0.05).C、D、E不同剂量组间比较,差异有统计学意义,即随用药剂量增大,兔关节液中TNF-α含量越低.结论 补肾益气药可能通过降低兔关节液中TNF-α含量预防骨性关节炎.%Objective To explore the mechanism of preventive effect of Chinese medicine with Replenishing kidney and invigorating Qi on osteoarthritis. Methods 72 male Long-eared white rabbits aged 4 months were randomly divided into six groups, A group (blank control group), B group (model group), C group (traditional Chinese medicine high-dose prevention group), D group (Chinese herbal medicine with medium-dose prevention group), E group (Chinese herbal medicine with low-dose prevention group), F group (glucose-amino acid hydrochloride capsules prevention group).All the animals apart from A group were established osteoarthritis model by immobilizing knee joint with plaster cast for 6 weeks

  9. 毛泽东心目中的理想社会——从《学生之工作》到《五七指示》%Mao Zedong's Ideal Society——From "Students Work" to "WuQi Instructions"

    Institute of Scientific and Technical Information of China (English)

    谢昌余

    2011-01-01

    "Students Work" and "WuQi Instructions" were written on December 1,1919 and May 7,1966.Biliteracy crossing long time and huge space,we can see that there is still a logical connection between them through serious study and repeated comparisons.It is not difficult to find old age and young Mao Zedong's pursuit of his ideal society with continuity,consistency and uniformity.The difference is that "critical bourgeois" task was added to "WuQi Instructions".%《学生之工作》和《五七指示》分别写于1919年12月1日和1966年5月7日。两文跨越的时空很大,但认真研读,反复比较,就能看到其中仍有一种合乎逻辑的联系,从中不难发现晚年毛泽东和青年毛泽东对他心目中理想社会的追求有着连续性、一贯性和统一性。所不同的是,和《学生之工作》相比,《五七指示》增加了"批判资产阶级"的任务。

  10. 卫分证、气分证、营分证Th1/Th2漂移变化规律研究%Study on the law of drifting of Th1/Th2 in wei phase syndrome, qi phase syndrome, ying phase syndrome of acute suppurative tonsillitis

    Institute of Scientific and Technical Information of China (English)

    刘旺华; 刘建新; 周小青; 谢静

    2013-01-01

    Objective To discuss the law of drifting of Th1/Th2 in wei phase syndrome, qi phase syndrome, ying phase syndrome of acute suppurative tonsillitis. Methods 50 patients were divided into wei phase syndrome group (20), qi phase syndrome group (15), ying phase syndrome group(15) according to differentiating symptoms of TCM, and 16 healthy people were selected as the normal control. The expressions of IL-2, TNF-β, IFN-γ, IL-4, IL-5, IL-6 and IL-10 were detected by ELISA. Results Compared with normal group, the levels of IL-2 and IFN-γ of wei phase syndrome group, qi phase syndrome, ying phase syndrome group increased significantly (P<0.05 or P<0.01), and the contain of TNF-β, IL-4, IL-5, IL-6 and IL-10 of qi phase syndrome, ying phase syndrome group improved markedly (P<0.01). Compared with wei phase syndrome group, the levels of IL-2, TNF-β, IFN-γ, IL-4, IL-5, IL-6 and IL-10 of qi phase syndrome increased instinctly (P<0.05 or P<0.01), and the levels of TNF-β, IL-4, IL-5, IL-6 and IL-10 increased markedly in ying phase syndrome group (P<0.01). Compared with qi phase syndrome group,the levels of IL-2, TNF-β and IFN-γ were tending downwards, and the level of IFN-γ decreased instinctly in ying phase syndrome group (P<0.01), while the levels of IL-4, IL-6 and IL-10 increased constantly. Conclusion Pathologic developing process from wei phase syndrome to qi phase syndrome and then to ying phase syndrome is correlated closely to the drifting of Th1/Th2 and the dynamic changes of IL-2, TNF-β, IFN-γ, IL-4, IL-5, IL-6 and IL-10 can be used as one of the objective indicators in differentiation of Wei-Qi-Ying-Xue.%目的 探讨卫分证、气分证、营分证Th1/Th2漂移变化规律,为卫气营血辨证提供客观的实验指标.方法 将50例患者按中医辨证分为卫分证组20例,气分证组15例,营分证组15例.另选择体检健康者16例为健康对照组.用ELISA法检测不同阶段患者血清Th1和Th2细胞因子白细胞介素(IL-2)、

  11. 益气活血法对脑出血大鼠脑内凝血酶敏感蛋白-1及其受体CD36表达的影响%Effects of Replenishing Qi and Promoting Blood Circulation Treatment on the Expression of Thrombospondin-1 and Receptor CD36 of lntracerebral Hemorrhagic Rats

    Institute of Scientific and Technical Information of China (English)

    陈柏林; 邢之华; 唐涛; 刘宜峰; 阳鹤鹏; 刘清娥; 吴汉军

    2011-01-01

    OBJECTIVE To make a primary study of the mechanism of replenishing qi and promoting blood circulation treatment for curing intracerebral hemorrhage (ICH) rats by observing the expression of thrombospondin-1 (TSP-1) and its receptor CD36. METHODS 155 SD rats were randomly divided into six groups, namely normal group, sham operated group, ICH model group, replenishing qi and promoting blood circulation treatment group, replenishing qi group and promoting blood circulation treatment group. ICH model was established by injecting collagenase type Ⅶ, while replenishing qi group, promoting blood circulation treatment group and replenishing qi and promoting blood circulation treatment group were respectively administered with replenishing qi decoction, promoting blood circulation treatment decoction and Buyang Huanwu Decoction. Afterwards, brain tissue was extracted different and the expression of TSP-1 and CD36 were detected by western blotting. RESULTS There was no significant changes in the expression of TSP-1 and CD36 between normal group and sham operated group at different time. In ICH model group, TSP-1 reached peak on the fourth day,CD36 on the 4th and 28th day. In replenishing qi and promoting blood circulation treatment group, the expression of TSP-1 was lower than that in model group on the 1st day(P<0.01); the expression of TSP-1 and CD36 was both lower than that in model group on the 4th day(P<0.01); the expression of CD36 was higher than that in model group on the 28th day(P<0.01).CONCLUSION Replenishing qi and promoting blood circulation treatment may regulate the expression of TSP-1 and its receptor CD36 in ICH rat, thus it can lower the inhibiting effect on angiogenesis and promote the shaping and maturity of new blood vessels as well as the recovery of brain tissue injury.%目的 通过观察益气活血法对脑出血大鼠脑内损伤区凝血酶敏感蛋白-1(thrombospondin-1,TSP-1)及其受体CD36表达的影响,初步探讨益气活血法

  12. Overview of Therapy on Qi-stagnancy and Blood Stasis Type of Angina Pectoris Based on Prescription Formulations of TCM%基于处方剂型的中医药治疗气滞血瘀型冠心病心绞痛概况

    Institute of Scientific and Technical Information of China (English)

    郭炜; 韩涛; 董文亮; 黄海量; 贾一青

    2011-01-01

    对气滞血瘀型冠心病心绞痛的中医治疗近况进行综述.从处方剂型角度出发,总结中医药治疗气滞血瘀型冠心病心绞痛的临床疗效;结合实验研究阐述该病证的病理生理特点,揭示中医对该病证的治疗机制,为今后临床治疗提供思路和方法.%To Snmnmrize TCM treatnent of reviewed recent developnents on Qi-stagnancy and Blood Stasis type of coronary heart disease. From the perspective of prescription formulations,summarized clinical efficacy of coronary heart disease in TCM treatment of Qi-stagnanancy and Blood Stasis type, pe of coronary heart disease; described the pathophysiology characteristics of disease with experimental evidence to discover therapeutic mechannism, and provide ideas and methods for future clinical treatment.

  13. Disappointment and Anxiety --Compare Tang poetry "chuzhou xi jian" and Modem Poetry "qi fu" in Symbol%失望与焦虑——比较唐诗《滁州西涧》和现代诗《弃妇》的“象征”运用

    Institute of Scientific and Technical Information of China (English)

    王四四

    2012-01-01

    "象征"是中国和欧洲都有的诗歌手法。唐诗《滁州西涧》和1920年代模仿法国象征派的新诗《弃妇》均采用"象征"来传达一种失望与焦虑之情绪。《滁州西涧》意象相接自然,因而意境浑圆,虽传达失望之情绪复又归于和谐。《弃妇》过度追求意象奇特,联结古怪,脱离了民族审美心理,诗里诗外都阴霾不散。%The symbol of Tang poetry "chuzhou xi jian" and modem poetry "qi fu" convey a disappointment and anxiety emotions. The "chuzhou xi jian "connect natural images, and artistic conception and round, although convey emotion to the complex and disappoint- ment ,finally harmonious. "qi fu" is image strange,so,Away from the national aesthetie psychology.

  14. Effect on Distribution and Expression ofμ-opioid Receptor in Hippocampus of Premenstrual Syndrome Liver-qi Stagnation Rat Model by Shu-Yu Capsule%舒郁胶囊对PMS肝气郁证模型大鼠海马μ阿片受体分布表达的影响

    Institute of Scientific and Technical Information of China (English)

    王美艳; 宋春红; 薛玲

    2015-01-01

    目的:探讨经前期综合征(PMS)肝气郁证模型大鼠海马脑区μ阿片受体(MOR)分布形态、蛋白水平表达,初步揭示PMS肝气郁证的发生机理及舒郁胶囊对该病证的干预作用.方法:采用慢性束缚应激法复制PMS肝气郁证模型大鼠,分别予以调肝方药舒郁胶囊进行干预.采用免疫荧光标记(IF)和蛋白免疫印迹(WB)技术对各组大鼠海马CA1、CA3脑区MOR进行检测.结果:与正常组大鼠相比,模型组大鼠海马脑区MOR分布排列杂乱且蛋白含量增多(P<0.01),给予药物干预后,MOR蛋白含量基本恢复至正常水平.结论:PMS肝气郁证的发病机理可能与大鼠海马中CA1、CA3区 MOR高表达有关;舒郁胶囊可以有效纠正其恢复近正常水平,这可能是舒郁胶囊治疗PMS肝气郁证的中枢机制之一.%This study was aimed to discuss the distribution and protein expression level ofμ-opioid receptor (MOR) in hippocampus of premenstrual syndrome (PMS) liver-qi stagnation rat model, in order to initially reveal the action mechanism of PMS liver-qi stagnation and intervention effect ofShu-Yu (SY) capsule. Chronic restraint stress method was used to copy PMS liver-qi stagnation rat model.SY capsule ofTiao-Gan prescription was given as intervention. Immunofluorescence (IF) and western blot (WB) technique were used to detect MOR in hippocampal CA1 and CA3 brain area of rats from each group. The results showed that compared with the normal group, the hippocampus MOR distribution arrangement was messy with increased protein concentration in the model group (P< 0.01). After drug intervention, the MOR protein level returned to normal level. It was concluded that the pathogenesis of PMS liver-qi stagnation may be associated with high expression of MOR in hippocampus CA1 and CA3 region of rats. SY capsule can effectively correct and restore it to nearly normal level. It may be one of the central mechanisms in SY capsule treatment of PMS liver-qi stagnation.

  15. The relationship between the stress-related psychosocial factors and the psychosomatic adjustment after surgery(II):The effect of Qi-Gong relaxation training%心理社会因素与手术康复(二):气功的干预作用

    Institute of Scientific and Technical Information of China (English)

    沈晓红; 姜乾金; 叶圣雅

    2001-01-01

    Objective To study the effect of Qi-Gong relaxation training on the operation-related psychological stress and the post-operative psychosomatic adjustment in upper-abdominal surgery patients. Methods Forty-two patients undergoing upper-abdominal surgery in intervention group were instructed to do Qi-Gong relaxation training, and forty patients matched were controls without Qi-Gong relaxation training. On the day before surgery, a self-developed patients' pre-operative appraisal questionnaire, a self-developed patients' pre-operative behavior rating questionnaire for completion by medical workers, and State Anxiety Inventory (SAI) of State -Trait Anxiety Inventory (STAI) were used in two groups. In an hour before operation,the shift of the mean value of pulse and systolic pressure of every case compared with the base line measured at his (or her) admission was also recorded. After surgery, patients were assessed with a self-developed patients' post-operative appraisal questionnaire, a self-developed patients' post-operative behavior rating questionnaire for completion by medical workers and SAI of STAI. Besides, the indexes of physical rehabilitation, including intestinal aerofluxus, total dosage of analgesia and so on, were recorded. Data were analysed in t-test with SPSS. Results Compared with controls, the patients in intervention group had more positive anticipation about the following operation, lower pre- and post-operative anxiety, and lighter post-operative pain experience. There was no difference in the indexes of physical rehabilitation between two groups. Conclusions Qi-Gong relaxation training could lead patients to better psychological adjustment both before and after operation. This finding suggests that Qi-Gong relaxation training could be used as an effective psycho-behavior intervention in abdominal surgery patients.%目的探索气功放松训练在外科心理应激及术后心身康复中的干预作用。方法随机选

  16. Effects of supplementing qi and activating blood circulation on piamatral microcirculation in gerbils with cerebral ischemic reperfusion%益气活血对脑缺血再灌注沙土鼠脑膜微循环的作用

    Institute of Scientific and Technical Information of China (English)

    俞国平; 戴良珏; 方敏; 谢荭

    2006-01-01

    通,红细胞中度聚集,白细胞数多,有时可见白色微小血栓,微血管周围渗出现象无明显改观.药物组经腹腔注射益气活血药后,细动、静脉开放,血液速度加快,血流量明显增加,细静脉沉积物开始减少,血栓凝块逐渐疏松,栓塞处疏通,红细胞呈轻度聚集或正常,缺血区血供较再灌流后进一步改善,微血管周围渗出现象逐渐减轻甚至消退.对照组未见明显改变.②药物组动物细动脉流速1.04~1.50 mm/s,明显高于对照组,差异有显著性意义(P<0.05~0.01).③药物组动物细静脉流速0.96~1.12 mm/s,明显高于对照组,差异有显著性意义(P<0.05~0.01).结论:益气活血法对沙土鼠脑缺血再灌注后脑膜微循环的作用确切,其直接作用与加快血流速度,扩张细动脉、细静脉管径,改善大脑血供等有关.%BACKGROUND: The key point in the treatment of acute cerebral infarction lies in inproving the blood supply of brain effectively as soon as possible as well as rescue ischemic and half diazonal nerve cells, so as to contract the local of infarction as great as possible.OBJECTIVE: To observe the effect of traditional treatment of cerebral piamatral microcirculation in gerbil with cerebral ischemic reperfusion injury by supplementing qi and activating blood circulation.DESIGN: Contrast animal experiment at random.SETTING: Zhabei Branch of Shanghai Changzheng Hospital.MATERIALS: The experiment was performed in the Institute of Naval Medicine (key laboratory of the whole army). Twenty-two healthy Monglian gerbils of clean grade (six months old) were selected and randomly divided into medicine group and control group with 11 gerbils in each group.METHODS: Animals were routinely anaesthetized and fixed in prone position to open the cranium window in median line and expose the pia mater. The cranium window was protected by being covered with a cotton ball containing artificial cerebrospinal fluid (ACSF) after operation. Gerbils were fixed in dorsal

  17. Clinical observation of massage on the community children with anorexia of spleen-stomach qi deficiency type%推拿治疗社区儿童脾胃气虚型厌食症的临床研究

    Institute of Scientific and Technical Information of China (English)

    罗汀

    2015-01-01

    目的:探讨医务人员指导下的家庭推拿治疗社区儿童脾胃气虚型厌食症的疗效。方法将60例脾胃气虚型厌食症患儿随机分为推拿1组和推拿2组各30例,在行为干预和膳食指导的基础上,推拿1组由社区医师采用健脾益气法选取穴位推拿治疗,推拿2组由医务人员指导患儿家长推拿。8周为一个疗程。比较两组治疗前后中医症状积分及临床疗效,记录治疗过程中的不良反应。结果治疗后,两组患儿食欲、食量、面色、神疲、口气、腹胀、大便等症候评分均显著降低,与治疗前比较,差异有统计学意义( P<0.05)。推拿1组痊愈12例,显效8例,有效9例,无效1例;推拿2组痊愈9例,显效6例,有效13例,无效2例,两组疗效差异无统计学意义( P>0.05)。结论推拿治疗儿童脾胃气虚型厌食症安全有效且简便,在医务人员指导下的患儿家长的推拿也可达到相同的效果。%Objective To explore the clinical effects of medical staff guided-home massage on the communi-ty children with anorexia of spleen-stomach qi deficiency type.Methods Sixty cases were randomly divided into the massage group 1(n=30) and the massage group 2(n=30).Besides the behavioral intervention and dietary guid-ance, the children in the massage group 1 received acupoint selected massage by community medical staff;the chil-dren in the massage group 2 received massage by parents under the guidance of community medical staff.All patients were treated for 8 weeks.The clinical symptom scores and clinical efficiency were compared before and after the treat-ment in both of the two groups and their adverse reactions were recorded.Results After the treatment, the clinical symptom scores of appetite, colour of face, mental weariness, halitosis, abdominal distension and stools in the two groups decreased greatly(P0.05) .Conclusion Massage is a safe, effective, convenient and simple treatment

  18. Research on Pre-reproduction behavior of White-napped in Qi xinghe Wetland%七星河湿地白枕鹤繁殖前期行为研究

    Institute of Scientific and Technical Information of China (English)

    赵国辉; 李晓民

    2012-01-01

      2012年4月15日~25日在七星河湿地对白枕鹤的繁殖前期行为规律进行了观察.繁殖前期的时间分配中觅食行为43.55%,警戒行为15.18%,游走行为13.79%,理羽行为12.20%,静栖行为11.81%,求偶行为2.48%,其余行为比较少;日节律显示:觅食行为在一天中出现三次高峰,即6:00~7:00、11:00~13:00和14:00~16:00;警戒行为和静栖行为则有一定程度的相似,分别在13:00和14:00左右,达到峰值;游走行为在下午达到低谷,在其他时间趋于稳定;理羽行为在一天中基本趋于稳定.求偶行为只出现在早晨和傍晚之间有两个间断峰值,无规律性.雌雄白枕鹤在理羽行为(p=0.018)和求偶行为(p=0.001)时间分配上存在显著性差异.其余行为时间分配上不存在显著性差异.%  The rhythm of behaviors of White-napped Crane in pre-reproductive period was observed at April 15~25, 2012 in Qi xinghe Wetland. The time budget of various behaviors in pre-re-productive stage was feeding (43.55%), alert (15.18%), walking (13.79%), preening (12.20%), resting (11.81% ), courtship (2.48%), and the else behaviors was rare. The behavior rhythm of White-napped Crane showed that feeding in one day appeared three peaks at 6:00~7:00, 11:00~13:00 and 14:00~16:00. Alert and resting were similar in the certain degree, respectively reached the peak at 13:00 and 14:00. Walking reached the trough at pm and then kept steady in other times. Preening tended to keep steady in a day. Courtship only had two discontinuous peaks and non-regularity. Significant difference was found for female and male between preening (p=0.018) and courtship (p=0.001). There was no significant difference in else behaviors.

  19. Centered on Strengthening Body Resistance and Nourishing Qi and Warming Yang%扶正为主,益气温阳为先——沈敏鹤诊治肿瘤的经验探究

    Institute of Scientific and Technical Information of China (English)

    张波; 沈敏鹤; 阮善明; 单飞瑜; 徐叶峰

    2012-01-01

    [Objective] To sum up director Shen Minhe's feature in recognizing tumor causa morbi and mechanism and clinical different treatment, thoughts, characteristics and rules from others; with clinical cases, it further proves his academic thought on treating tumor and science of clinical experience, for better guiding clinically diagnosing and treating tumor. [Method] The author clears up Mr. Shen's medical cases, recipes and collects his lecture data, individual notes, special interview, thesis and works, analysis on his medication, formulae, differentiation thoughts and experience; by retrieving ancient TCM books and analyzing famous TCM doctors's academic thoughts, he finishes the summary on doctor Shen Minhe's academic thought and clinical experience. [Result] Shen's thought mainly originates from classical works, such as "Internal Classics", " Treatise on Febrile Diseases" and "Synopsis on Golden Chamber", his main treatment rule is centered on strengthening the body resistance and nourishing Qi and warming Yang. [Conclusion] To take Shen's experience for treating tumor from essence, deficiency, congealing cold, and apply his rule can markedly relieve tumor patients' clinical symptoms, reduce its re-occurrence and metastasis and obviously improve patients' life quality.%[目的]总结沈敏鹤主任中医师对肿瘤病因病机的认识及临床不同于其他医家的治疗特色、用方思想、用药特色和规律;通过临床实证进一步验证沈师治疗肿瘤的学术思想和临床经验的科学性,以便更好的指导肿瘤的临床诊治.[方法]笔者随沈师出诊,整理其医案、验方并收集沈师讲课资料、个人笔记、专题访谈、论文和著作,分析其用药、用方和辨证思路与经验;通过中医古籍的检索以及对导师影响较大的名老中医学术思想的分析,完成沈敏鹤主任中医师学术思想和临床经验的整理与总结.[结果]沈师的思想渊源主要来源于《内经》、《伤

  20. Treating 52 cases of gynecological chronic pelvic pain (qi stagnation and blood stasis type) by herbal penetration therapy%中药外治法治疗妇科慢性盆腔痛(气滞血瘀型)52例

    Institute of Scientific and Technical Information of China (English)

    陈琰; 王赛莉; 赵燕宁

    2012-01-01

      Objective: To observe the clinical curative effects of herbal enema and herbal penetration therapy in treating gynecological chronic pelvic pains and investigate the mechanism of relieving pains. Methods: 52 cases of patients with gynecological chronic pelvic pains were selected and treated with herbal enema and herbal penetration therapy. The variation of pain scores before and after treatment was observed to evaluate the improvement of chronic pelvic pains by herbal enema and herbal penetration therapy, while the TCM syndromes scores and Hamilton depression scores (24 items) were observed to evaluate the improvement of TCM syndromes of chronic pelvic pain and the affection of depressed emotion by herbal enema and herbal penetration therapy. Results: Syndromes of chronic pelvic pain improved obviously after treatment. The total effective rate was 88.46%. There was a significant difference between the pain scores before and after treatment (P<0.01). The depressed emotion of patients improved a lot along with the relieving of pains. There was a significant difference between the Hamilton depressed scores before and after treatment (P<0.01). Conclusion: The herbal enema and herbal penetration therapy had an obvious effect in dispersing the depressed liver-energy, promoting Qi, warming meridians, activating blood circulation, removing blood stasis and pains. It was worthy of wide application because it could relieve the syndromes of chronic pelvic pain and improve the depressed emotion of patients, and in addition it was convenient, effective and with little side effects.%  目的:观察中药灌肠、中药外敷治疗气滞血瘀型妇科慢性盆腔痛的临床疗效,探讨其缓解疼痛的作用机理.方法:选择妇科慢性盆腔痛(气滞血瘀型)患者52例,予中药保留灌肠、中药外敷治疗两个疗程,通过观察治疗前后数字疼痛评分(NRS)的变化,评价中药灌肠、外敷对妇科慢性盆腔疼痛的改善情

  1. Effect of Qi Hong San on BNP and ET-1 in chronic heart failure rats%芪红散对慢性心衰大鼠BNP及ET-1水平的影响

    Institute of Scientific and Technical Information of China (English)

    王东; 刘江; 王晓峰

    2016-01-01

    significantly lower than that in model group (P <0.01~0.05).Conclusion Qi Hong San can reduce the level of BNP and ET-1 in serum,improve heart function and reduce the symptoms of heart failure.

  2. Mitochondrial Reactive Oxygen Species Scavenging Investigations of Astragalus Membranaceus/Codonopsis Pilosula Qi-invigorating Herbal Tea%芪参补气药茶清除线粒体活性氧研究

    Institute of Scientific and Technical Information of China (English)

    李兴太; 韦豪华; 张红玲; 孙海波; 苏亚茹

    2015-01-01

    Astragalus membranaceus/Codonopsis pilosula Qi-invigorating herbal tea ( ACT) was prepared from Astragalus membranaceus and Codonopsis pilosula according to traditional Chinese medicine principle. Mitochondrial reactive oxygen species scavenging activity of ACT and the underlying health - promoting mechanism were investigated. Total flavonoids, total carbohy-drates and total polysaccharides, which are the functional factors of ACT, were determined by AlCl3 colorimetry, and sulfuric acid and phenol method respectively. The scavenging activities of ACT on superoxide anion ( O2 ·-) and hydroxyl radical ( ·OH) , which were produced by re-duced nicotinamide adenine dinucleotide ( NADH )/N - Methylphenazonium methyl sulfate ( PMS) and hydrogen peroxide ( H2 O2 )/Fe2+ system respectively, were measured by NBT re-duction and Fenton reaction colorimetry. The Na2 S2 O3 titration method was used to measure the scavenging activities of ACT on H2 O2 . The contents of total carbohydrates, total polysaccharides and total flavonoids of ACT were 26 ± 1. 3 mg/mL, 12. 5 ± 0. 8 mg/mL and 121 ± 8. 5 μg/mL, respectively. ACT could scavenge O2·-, ·OH and H2O2. According to the research, ACT has mild antioxidation, therefore, the balance of oxidation and antioxidant ( redox balance) was maintained, and this maybe the underlying mechanism of the health benefits for ACT.%以黄芪和党参为原料,根据中医学原理组方制成芪参补气药茶(ACT),探索ACT清除线粒体活性氧作用及促进健康的机制. 分别用AlCl3 比色法和硫酸苯酚法测定ACT的功能因子总黄酮、总糖及总多糖含量. 以还原型辅酶Ⅰ/吩嗪硫酸甲酯( NADH/PMS)为超氧阴离子( O2 ·-)生成系统,过氧化氢( H2 O2 )/Fe2+体系为羟自由基( ·OH)生成系统,分别用氮蓝四唑( NBT)还原法和Fenton反应显色法测定ACT清除O2 ·-及·OH的能力;用Na2 S2 O3 滴定法测定ACT清除H2 O2 的能力. ACT总糖质量分数为(26 ±1.3) mg·mL-1,

  3. Logistic regression analysis on syndrome factors of viral myocarditis in children with syndrome of qi and yin deficiency%儿童病毒性心肌炎气阴两虚证证候要素的Logistic回归分析

    Institute of Scientific and Technical Information of China (English)

    徐曼曼; 任光明

    2016-01-01

    目的:探讨儿童病毒性心肌炎气阴两虚证证候要素的分布规律。方法将200例病毒性心肌炎患儿分为气阴两虚证组、风热犯心证组、湿热侵心证组、心阳虚弱证组,进行证候要素分布调查,采用因子分析,二项分类、多因素非条件Logistic回归分析等方法进行分析。结果因子分析结果提示儿童病毒性心肌炎气阴两虚证并非单纯的心系的气阴两虚,其病机涉及多个脏腑,是一个综合的脏腑病机演变过程。二项分类回归分析显示,气阴两虚证组与非气阴两虚证组(包括风热犯心证组、湿热侵心证组、心阳虚弱证组)证候要素比较,在胸闷或胸痛、面色苍白、心律改变、心音低钝、心烦、寐差、乏力、头晕、纳差、完谷不化、善太息、默默不语、手足热方面比较差异有统计学意义(P<0.05)。多因素非条件Logistic回归分析结果提示心律改变、心音低钝、头晕、完谷不化、善太息、默默不语等6项证候要素对儿童病毒性心肌炎气阴两虚证具有诊断意义。结论儿童病毒性心肌炎气阴两虚证的病机演变过程中,肝脾两脏起重要作用。%Objective To explore the distribution rule of syndrome factors of viral myocarditis ( VM) in children with syndrome of qi and yin deficiency. Methods Total200 children with VM were designated into deficiency of qi and yin group, invasion of the heart by wind-heat group, invasion of the heart by damp-heat group, deficiency of heart yang group. Then the distribution of syndrome factors were studied by using the method of factor analysis, binary logistic regression analysis and multinomial logistic regression analysis. Results By using the method of factor analysis, syndrome of qi and yin deficiency was more than syndrome of deficiency of heart qi and yin , which was a comprehensive procedure of pathogenesis development of zang-fu organs. The results of binary

  4. 益气涤痰化瘀方对哮喘小鼠气道炎症及Th1/Th2平衡的影响%Effects of YiQi DiTan HuaYu Formula on Th1/Th2 Balance and Airway Inflammation of Mice with Asthma

    Institute of Scientific and Technical Information of China (English)

    赵文娟; 袁嘉丽; 陈静; 邢海晶; 韩妮萍

    2015-01-01

    目的:探讨益气涤痰化瘀方对哮喘小鼠气道炎症及Th1/Th2平衡的调节作用。方法:将SPF级BALB/c雌性小鼠50只随机分为正常对照组、哮喘模型组,益气涤痰化瘀方低、中、高剂量组。采用卵清白蛋白(OVA)腹腔注射及雾化激发法构建哮喘模型,益气涤痰化瘀方干预治疗。观察各组小鼠行为学改变;制作肺组织病理切片行镜下观察;收集肺泡灌洗液(BALF)进行白细胞总数及分类计数;取小鼠血清以ELISA法检测IFN-γ、IL-4的变化。结果:1)与哮喘模型组比较,药物干预组哮喘症状有所减轻,肺组织炎性细胞浸润减轻;2)益气涤痰化瘀方中剂量组小鼠BALF中白细胞总数和嗜酸性粒细胞(EOS)、中性粒细胞(NEU)、淋巴细胞(LYM)分类计数较哮喘模型组减少(P<0.05);3)与哮喘模型组比较,益气涤痰化瘀方高、中剂量组小鼠血清IFN-γ浓度升高(P<0.05),IL-4浓度降低(P<0.05)。结论:益气涤痰化瘀方可对免疫细胞Th2优势所致的免疫失衡状态进行调节,恢复Th1/Th2平衡;益气涤痰化瘀方可能通过调节机体平衡而减轻哮喘急性气道炎性病变,从而起到防治哮喘的作用。%Objective:To observe the adjustment of YiQi DiTan HuaYu formula to Th1/Th2 balance and air-way inflammation of mice with asthma. Methods:Fifty SPF BALB/c female mice were randomized into normal con-trol group, asthma model group, high, moderate and low dosages groups of YiQi DiTan HuaYu formula. The mice models were established through peritoneal injection of ovalbumin (OVA) and atomization-excited method, and they were intervened by YiQi DiTan HuaYu formula. To observe behavioral changes of the mice in different groups;to prepare pathological section of the lung and observe the section under the microscope; to count total white blood cells and classifications after collecting broncho-alveolar lavage fluid (BALF);to draw the serum from the mice and to

  5. 应用fMRI技术探查静息态经前期综合征肝气郁证患者中枢脑区定位%Application of fMRI Technology in Exploration of Central Brain Localization among Premenstrual Syndrome Patients with Liver-qi Depression in Resting-state

    Institute of Scientific and Technical Information of China (English)

    高冬梅; 于艳红; 侯艳娇; 刘晓琴; 乔明琦

    2015-01-01

    This study was aimed to explore brain regions which were closely related to the disease onset of premenstrual syndrome (PMS) with liver-qi depression. The BOLD-functional magnetic resonance imaging (fMRI) was used in the study. The processing of imaging data was based on the SPM 8 software and the REST software of the matlab platform. Each cluster was more than 389 continuous voxel. The brain region with single voxel of P < 0.05 (corrected) was defined as region with statistical significance. The 2 Sample T-Test was applied in the case group and the control group. The results showed that compared with the normal control group, the frontal lobe, occipital lobe, insula, limbic lobe, basal nuclei, and cingulate gyrus were activated in the PMS with liver-qi depression cases. It was concluded that the disease onset of PMS with liver-qi depression cases was related to brain regions such as frontal lobe, occipital lobe, insula, limbic lobe, basal nuclei, and cingulate gyrus.%目的:探寻与经前期综合征肝气郁证发病密切相关的脑区.方法:采用BOLD-功能磁共振成像技术,影像学数据基于matlab平台的SPM 8软件以及rest软件进行图片处理,每个簇块体积阈值(Cluster)大于389个连续体素,单体素阈值P<0.05(校正后)的脑区定义为差异有统计学意义的区域,病例组和对照组采用双样本t检验.结果:PMS肝气郁证患者与正常对照相比,额叶、枕叶、岛叶、边缘叶、基底核、扣带回等脑区激活增强.结论:PMS肝气郁证患者发病与额叶、枕叶、岛叶、边缘叶、基底核、扣带回等脑区有关.

  6. Clinical Study on Abdominal Acupuncture plus Herbal Medicine for Chronic Pelvic Pain Due to Qi Stagnation and Blood Stasis%腹针配合中药治疗气滞血瘀型慢性盆腔痛的临床研究

    Institute of Scientific and Technical Information of China (English)

    宋玉娟; 张殿全; 苏丹萍

    2015-01-01

    Objective To observe the clinical efficacy of abdominal acupuncture plus herbal medicine in treating chronic pelvic pain due to qi stagnation and blood stasis after pelvic inflammatory diseases.Method Sixty patients with chronic pelvic pain due to qi stagnation and blood stasis after pelvic inflammatory diseases were randomized into a treatment group and a control group, 30 in each group. The treatment group was intervened by abdominal acupuncture plus herbal medicine, while the control group was by herbal medicine alone. After 3 menstrual cycles, the Visual Analogue Scale (VAS) for abdominal pain and McCormack scale were observed.Result After intervention, the abdominal VAS score and McCormack score were changed significantly in both groups (P<0.01,P<0.05). After intervention, there were significant differences in comparing the VAS score and McCormack score between the two groups (P<0.01).Conclusion Abdominal acupuncture plus herbal medicine can reduce chronic pelvic pain due to qi stagnation and blood stasis after pelvic inflammatory diseases.%目的:观察腹针配合中药治疗盆腔炎性疾病后气滞血瘀型慢性盆腔痛的临床疗效。方法将60例盆腔炎性疾病后气滞血瘀型慢性盆腔痛患者随机分为治疗组和对照组,每组30例。治疗组采用腹针配合中药治疗,对照组采用单纯中药治疗。治疗3个月经周期后,观察两组治疗前后腹痛VAS评分及McCormack量表评分变化。结果两组治疗后腹痛VAS评分及McCormack量表评分与同组治疗前比较,差异均具有统计学意义(P<0.01,P<0.05)。治疗组治疗后腹痛VAS评分及McCormack量表评分与对照组比较,差异均具有统计学意义(P<0.01)。结论腹针配合中药能够减轻盆腔炎性疾病后气滞血瘀型慢性盆腔痛。

  7. 补中益气汤加减联合司来吉兰治疗帕金森病伴功能性便秘的疗效观察%Clinical Observation on Bu-zhong Yi-qi Decoction Combined with Selegiline for Parkinson's Constipation

    Institute of Scientific and Technical Information of China (English)

    毕树立; 刘斌; 高海英

    2014-01-01

    目的:探讨补中益气汤加减联合司来吉兰治疗帕金森病伴功能性便秘的临床疗效及安全性。方法:选择本病患者124例,根据治疗方式不同分成治疗组和对照组,两组均常规应用复方多巴和司来吉兰治疗帕金森病,治疗组在此基础上加用补中益气汤加减治疗便秘,对照组给予酚酞片,对比分析两组患者治疗的临床疗效和不良反应。结果:治疗组的总有效率86.4%,明显高于对照组70.7%,差异有统计学意义(P<0.05)。治疗组总不良反应发生率6.1%,明显小于对照组32.8%,差异有统计学意义(P<0.01)。结论:补中益气汤加减联合司来吉兰治疗帕金森病伴功能性便秘有较好的临床疗效。%Objective: To study the clinical curative effect and safety for the Bu-zhong Yi-qi decoction combined with selegiline on Parkinson's constipation. Methods: The 124 cases of Parkinson constipation patients were selected; According to different treatment, the patients were divided into treatment and control groups. Besides compound dopamine and selegiline to treat Parkinson's disease in two groups; patients were treated with Bu -zhong Yi -qi decoction in treatment group, and phenolphthalein pills in control group. The clinical efficacy and adverse reactions were compared in two groups. Results: The total effective rate was 86.4% in treatment group, which was obviously higher than the control group with 70.7% , with statistically significant difference (P<0.05). The total incidence of adverse reaction was 6.1% in treatment group, which was lower than the control group with 32.8% , with statistically significant difference (P <0.01). Conclusion:Bu -zhong Yi -qi decoction combined with selegiline can provide good clinical curative effect on Parkinson's constipation.

  8. Compaea tine Experimental Research among Three Methods for Building Diabetes "Qi Stagnation and Blood Stasis" Syndrome Animal Model%三种方法建立糖尿病气滞血瘀证型大鼠模型的对比实验研究

    Institute of Scientific and Technical Information of China (English)

    陈嘉斌; 柴可夫; 郑杨; 许斌斌; 季也民; 何贤松; 陈聿恒

    2013-01-01

    [Objective]To evaluate the three experimental methods of building the diabetes Qi stagnation and blood stasis syndrome animal model. [Method] 60 SD rats were divided into two groups: 10 in blank group and 50 in experimental group randomlwas. Experimental group was established the diabetes animal model with high fat and sugar feeding+STZ injection duplex method, there were three groups after sifting, which were separately put in the methods of lavage of traditional Chinese medicine, stimulation of electro acapuncture and insection of adrenaline to establish diabetes Qi stagnation and Blood stasis syndrome animal model. Observing the condition of model's symptoms and signs, index changes. [Results] Compared with Electro -acupuncture group and Adrenaline group, Lavage of traditional Chinese medicine group showed great statistical differences in BG, plasma viscosity, whole blood high and low cut, HGB,WBC, RBC, ALB Cr projects, little ordinary in symptoms and signs. [Conclusion] High fat and sugar feeding+STZ injection duplex with Lavage of traditional Chinese medicine is a relatively better method for establishing diabetes Qi stagnation and Blood stasis syndrome animal model in comparison.%[目的]评价三种建立糖尿病气滞血瘀证型大鼠模型的方法.[方法]60只SD大鼠随机分为空白组10只与实验组50只.实验组运用高脂高糖饲料+STZ注射二联法建立糖尿病动物模型,筛选后随机分3组,分别运用中药灌胃、电针刺激与肾上腺素注射的方法建立气滞血瘀证型糖尿病动物模型,观察症状体征、血液指标的变化情况.[结果]与电针刺激组、肾上腺素组比较,中药灌胃组在血糖、血浆粘度、全血高低切、HGB、WBC、RBC、ALB Cr项上表现出显著统计学差异(P<0.05),症状体征方面稍不及其他两组.[结论]相比较下运用二联法联合中药灌胃建立糖尿病气滞血瘀证型动物模型是一种较好的建模方法.

  9. Diagnosis principles and treatment steps of thoracic obstruction in Synopsis of Golden Chamber based on concept of physique and qi%基于“形气”观的《金匮要略》胸痹病分证及诊治步骤分析

    Institute of Scientific and Technical Information of China (English)

    徐慧颖; 李成卫

    2015-01-01

    To better understanding of the concept system and recipe idea in the Synopsis of the Golden Chamber ,based on the concept of physique and qi ,validates diagnostic principles and treatment steps in Synopsis of the Golden Chamber thoracic obstruction by way of illustration .Utilizing the concept system and recipe idea in Synopsis of the Golden Chamber to compre-hend the book is closer to the original meaning of the book by using the modern theory to explain the book .In the diagnosis and treatment system from Synopsis of the Golden Chamber ,the concept of physique and qi is not only adopted to cure the thoracic obstruction ,but also form treatment steps which should remove the visible pathological products firstly and regulate stagnant qi secondly .This conclusion contributes to deepen the understanding the original of the book ,which is also a good way to explore the original diagnosis and treatment system .It makes contribution to enrich and develop the miscellaneous dis-eases diagnosis and treatment system .At the same time it promotes the development of modern theory about the treatment ac-cording to syndrome differentiation .%为更好地理解《金匮要略》原著的诊疗体系及组方思路,基于原著中形气概念,以胸痹为例分析验证原著疾病分证原则、治疗处方的步骤方法,此方法较现代运用后世理论阐释原著更能揭示其本义。在《金匮要略》中对胸痹的治疗不仅应用了形气分证原则,还包含了“一祛有形实邪,二理无形病气”的形气处方思路与步骤。此结论加深了对《金匮要略》原文的理解,从另一个角度探索了《金匮要略》诊疗体系,同时为丰富和发展《金匮要略》杂病诊治体系,推动现代中医诊疗体系提供借鉴。

  10. Effect of Soothing Liver and Invigorating Spleen Recipes on Exterior Signs, ET and NO in Liver-qi Stagnation Syndrome of Chronic Gastritis Rats%疏肝健脾方药对慢性胃炎肝郁证模型大鼠外在表征及NO、ET的影响

    Institute of Scientific and Technical Information of China (English)

    任健; 陈宇

    2012-01-01

    目的:研究疏肝健脾方药对慢性胃炎肝郁证模型大鼠外在表征及血清一氧化氮(NO)和内皮素(ET)的影响,探讨其疗效机制.方法:采用氨水加慢性束缚法复制慢性胃炎肝郁证模型,设正常组、模型组(病证组)、疏肝健脾方药高剂量组、疏肝健脾方药低剂量组.测定NO含量(硝酸还原酶法)及ET含量(ELISA法).结果:病证组大鼠外在表征发生明显改变.各给药组大鼠的在给药后外在表征发生好转.病证组大鼠ET、NO逐渐升高,而给药组ET水平均低于病证组(P<0.05),NO未见明显变化.结论:疏肝健脾方药可通过调节ET水平,改善慢性胃炎肝郁证的外在表征以及胃血管血流,从而发挥较好的慢性胃炎防治作用.%Objective o To explore the effect and mechanisms of soothing liver and invigorating spleen recipes on the exterior signs, ET and NO in liver - qi stagnation syndrome of chronic gastritis rats. Methods: The model of liver - qi stagnation syndrome of chronic gastritis was established in accordance with the previous experience of combined ammonia water and Chronic astricting in rats. The rats were randomly divided into 4 groups:normal group, model group (liver -qi stagnation of chronic gastritis group) ,low - dose and high - dose group. The level of NO was detected by nitrate reductase test and that of ET by ELISA method. Results: The exterior signs of model group were changed significantly and every dose of rats group getted better after being given soothing liver and invigorating spleen recipes. The level of NO and ET of model group were increased. The level of ET of every dose group were lower than model group and the level of NO was not statistically significant. Conclusion; Soothing liver and invigorating spleen recipes can regulate the level of ET and improve the exterior signs and gastric blood flow,which plays a a preferable role in prevention and treatment of chronic gastritis.

  11. 丹七川故饮合深部热疗治疗良性前列腺增生伴膀胱过度活动症的临床观察%Clinical observation on treating BPH concomitant with OAB in Dan-qi-chuan-gu-yin plus deep-part thermotherapy

    Institute of Scientific and Technical Information of China (English)

    田亚伟; 夏阳; 王文杰

    2015-01-01

    目的:探讨丹七川故饮合深部热疗治疗良性前列腺增生伴膀胱过度活动症的临床疗效和安全性。方法:选择BPH伴OAB患者23例,口服自拟中药方丹七川故饮和进行深部热疗12周,治疗前后分别评价IPSS、OABSS、Qmax、尿急次数、日间排尿、夜尿等指标。结果:治疗后IPSS评分、OABSS评分、Qmax、尿急次数、日间排尿次数、夜尿次数等指标均较治疗前有改善,有统计学意义(P<0.01)。23例患者均未出现尿储留及不良反应。结论:丹七川故饮合深部热疗治疗良性前列腺增生伴膀胱过度活动症患者疗效满意,安全性高。%Objective: To observe the clinical effect and safety of treating BPH concomitant with OAB in Dan-qi-chuan-gu-yin plus deep-part thermotherapy. Methods:23cases were treated with Dan-qi-chuan-gu-yin plus deep-part thermotherapy 12 weeks. IPSS, OABSS, Qmax, urgency, urination in the day and night urination respectively were evaluated before and after treatment. Results: The above indexes are better in pretreatment than that of posttreatment (P<0.01).Urinary retention and adverse reactions do not appear in all 23 cases. Conclusion: Dan-qi-chuan-gu-yin plus deep-part thermotherapy has positive curative effect and safety on treating BPH concomitant with OAB.

  12. 气血瘀滞型原发性痛经中医身心同治的临床疗效观察与分析%Observation on and Analysis of the Clinical Efficacy of Mental and Physical Therapy in Patients with Qi or Blood Stagnation Type of Primary Dysmenorrhea

    Institute of Scientific and Technical Information of China (English)

    柴华; 王嘉梅

    2015-01-01

    Objective:To observe the clinical efficacy of mental and physical therapy on patients with Qi or blood stagnation type of primary dysmenorrhea.Methods:A total of 1 20 patients with Qi or blood stagnation type of primary dysmenorrhea were random-ly divided into the intervention group and the control group with 60 cases in each.Chinese medicine were given to both the inter-vention group and the control group,and additional psychological intervention was given to the control group.Comparison was made on the effective rate between the two groups after three courses of treatment.Results:The total effect rate of the intervention group was 93.33% and that of the control group was 80.00%,which means that the intervention group had a higher effective rate than the control group.The results are of statistical difference (P <0.05).Conclusion:Mental and physical therapy can effec-tively relieved the symptoms of Qi or blood stagnation type of primary dysmenorrhea.%目的:观察基于中医理论的身心同治方法对气血瘀滞型原发性痛经的临床疗效。方法:将120例气血瘀滞型原发性痛经的门诊患者随机分为治疗组和对照组各60例,2组均给予中药治疗,治疗组在中药治疗的基础上进行心理干预,3个月后观察2组有效率。结果:治疗组总有效率为93.33%,对照组总有效率为80.00%,治疗组总有效率高于对照组,且具有统计学意义(P <0.05)。结论:采用身心同治的综合干预方法治疗气血瘀滞型原发性痛经临床效果显著。

  13. 益气健脾补肾方在中晚期恶性肿瘤化疗中的疗效观察%Efficacy Observation of Qi Enriching, Invigorating Spleen and Kidney Tonifying Prescription during Chemotherapy of Patients with Moderate and Advanced Malignant Tumor

    Institute of Scientific and Technical Information of China (English)

    寿辉; 宣志红

    2013-01-01

    OBJECTIVE: To observe therapeutic efficacy of Qi enriching, invigorating spleen and kidney tonifying prescription during chemotherapy of patients with moderate and advanced malignant tumor. METHODS: 80 patients with moderate and advanced malignant tumor were randomly divided into 2 groups. Control group was given chemotherapy alone, and experimental group was addtionaly given Qi entiching, invigorating spleen and kidney tonifying prescription (one dose each day) on the basis of chemotherapy for 21 days. Therapeutic efficacy, adverse drug reaction and survival quality of 2 groups were observed. RESULTS: Compared with control group, clinical efficacy of trial group was improved significantly, and adverse drug reactions like bone marrow suppression and renal function impairment were lessened obviously and the life quality of patients was improved (P< 0.05). CONCLUSION: Qi enriching, invigorating spleen and kidney tonifying prescription can enhance the curative effect of chemotherapy for patients with moderate and advanced malignant tumor, improve the life quality of patients and reduce adverse drug reactions.%目的:观察益气健脾补肾方在中晚期恶性肿瘤化疗中的疗效.方法:将80例中晚期恶性肿瘤患者随机均分为两组,对照组单纯化疗,试验组单纯化疗结合益气健脾补肾方(每日1剂),疗程均为21d.观察两组患者疗效、不良反应与生存质量.结果:与对照组比较,试验组临床疗效显著增强,骨髓抑制与肾功能损伤等不良反应显著减轻,患者生存质量显著改善(P<0.05).结论:益气健脾补肾方可以提高中晚期恶性肿瘤化疗效果,减轻不良反应,提高患者生存质量.

  14. 益气透脓解毒法治疗急性化脓性扁桃体炎60例%Treating 60 Patients Suffering from Acute Suppurative Tonsillitis by YiQi TouNong JieDu Method

    Institute of Scientific and Technical Information of China (English)

    赵文; 孟凡琳

    2015-01-01

    Objective: To observe clinical effects of YiQi TouNong JieDu method in treating acute suppurative tonsillitis. Methods: All 120 patients were randomly allocated to two groups in the ratio of 1:1, the control group re-ceived anti-inflammation therapy, the treatment group TouNong powder, PuJi XiaoDu drink, TianHuaFeng(Trichosan-this Radix) and YiYiRen (Semen Coicis) to invigorate Qi, draw out pus and detoxifying. The score improvements of the symptoms including fever, sore throat, secreta and others were observed in both groups. Results: The treatment group was superior to the control group in the score improvements of the symptoms including fever, sore throat and secreta(P<0.05). Conclusion: YiQi TouNong JieDu method is effective in treating acute suppurative tonsillitis, it could improve the symptoms and body signs such as sore throat, secreta and fever.%目的:观察益气透脓解毒法治疗急性化脓性扁桃体炎的临床疗效。方法:将120例患者按1∶1比例随机分为2组,对照组给予抗感染治疗,治疗组给予益气透脓解毒法之透脓散合普济消毒饮加天花粉、薏苡仁治疗。观察2组患者治疗后发热、咽痛、分泌物等症状积分改善情况。结果:治疗后发热、咽痛、分泌物等症状积分改善治疗组优于对照组(P<0.05)。结论:益气透脓解毒法治疗急性化脓性扁桃体炎临床疗效肯定,可改善咽部疼痛、发热等症状,减少分泌物。

  15. 央芪膏外敷配合高频热疗治疗原发性肝癌的临床研究%Clinical Study on Treatment of Primary Hepatic Carcinoma with External Application of Yang Qi Gao Plus High Frequency Thermotherapy

    Institute of Scientific and Technical Information of China (English)

    唐万和; 孙易娜; 蔡昂; 余智勇; 吴迪; 王熙

    2011-01-01

    目的:观察央芪膏外敷配合高频热疗对原发性肝癌患者的临床疗效.方法:36例确诊为原发性肝癌患者随机分为对照组(单纯高频热疗组)18例、治疗组(央芪膏外敷配合高频热疗组)18例,连续治疗30天后,观察两组患者的近期疗效、生活质量、疼痛、甲胎蛋白(AFP)的变化等.结果:央芪膏外敷配合高频热疗较单纯高频热疗能显著提高患者的近期疗效、生活质量、明显减轻疼痛、降低肿瘤标志物AFP的水平.结论:央芪膏配合高频热疗产生了协同增敏的作用,疗效确切,可作为一种新治疗方案为原发性肝癌患者所应用.%Objective: to observe the effect of Yang Qi Gao plus high frequency thermotherapy in treating patients with Primary hepatic carcinoma. Methods :36 patients with confirmed diagnosis of Primary hepatic carcinoma were selected and randomly divided into two groups :18 patients in the control group with high frequency thermotherapy alone, 18 patients in the treated group were administered with Yang Qi Gao plus high frequency thermotherapy. After 30 days, two groups were observed with short - term effect、quality of life、pain、changes in AFP and other projects. Results:The effective rates and the disease control rates in the treated group were superior to those in the control group. As well as improved the QOL、decreased pain and levels of tumor marks (AFP). Conclusion: Yang Qi Gao plus high frequency thermotherapy plays a synergistic role and can be used as a new treatment to patients with Primary hepatic carcinoma.

  16. Positron emission tomography of cerebral function during electroacupuncture in Ganshu (BL18) and Qimen (LR14) in rat model of liver-qi depression syndrome%电针肝俞、期门对肝气郁结模型大鼠正电子发射脑功能成像研究

    Institute of Scientific and Technical Information of China (English)

    刘子旺; 赵海滨; 张秀静; 单保慈; 刘华; 贺立娟

    2012-01-01

    Objective To obtain the visible evidence of electroacupuncture regulating injured cerebral function in liver-qi depression syndrome by applying positron emission tomography ( PET) of cerebral function, and explore the mechanism of its effect on nerve center. Methods Wistar rats ( n = 20) were divided into model group of liver-qi depression syndrome ( model group) and treatment group of electroacupuncture ( treatment group) according to body weight. The two groups were given 18F fluorodeoxyglucose (18F-FDG) PET imaging scanning respectively before and after modeling. The data of two groups before and after modeling were treated with two-sample t-test (P < 0. 001) by using SPM2 imagine analysis software, and the regions with brain glucose metabolism changes in bver-qi depression syndrome regulated by electroacupuncture were obtained. Results The visible evidence of electroacupuncture regulating injured cerebral function in liver-qi depression syndrome has been obtained initially. Compared with model group, the cerebral regions with decreased glucose metabolism in treatment group included left frontal lobe, parietal lobe, paracentral lobule, supracallosal gyrus, thalamus and hypothalamus, and the regions with increased glucose metabolism included left basal ganglion, temporal lobe, right frontal lobe and subthalamus besides left frontal lobe and parietal lobe. Conclusion The glucose metabolism in different cerebral regions can be influenced after electroacupuncture in Ganshu (BL18) and Qimen (LR14).%目的 采用正电子发射计算机断层显像(PET)脑功能成像技术,获取电针调控肝气郁结证脑功能受损客观可视性依据,探讨其中枢作用机制.方法 将Wistar大鼠20只按体重随机分为肝郁模型组、电针治疗组,分别于造模前后进行氟18脱氧葡萄糖(18F-FDG) PET脑功能成像扫描,应用SPM2图像分析软件对模型组和电针组造模前后数据进行双样本t检验(P<0.001),获得电针调控肝气郁结证

  17. 经前期综合征肝气郁证大鼠血清对海马神经元5-HT1AR信号转导通路的影响%Effects of the Serum from Rats with Premenstrual Syndrome Liver-qi Depression on 5-HT1AR Signal Transduction Pathway of Hippocampal Neurons

    Institute of Scientific and Technical Information of China (English)

    金航; 张惠云

    2012-01-01

    OBJECTIVE: To study the effects of serum from rat with premenstrual syndrome (PMS) depression liver-qi on the expression of SERT, MAO-A.MAO-B related to 5-HT1A receptor signal transduction pathway of rat primary cultured hippocampal neurons. METHODS: Rat model of PMS depression liver-qi was prepared by chronic restraint stress; HPLC method was adopted to detect the content of 5-HT in serum; Then we applied semi-quantitative RT-PCR and Western blot to detect the effect of rat serum on the expression of 5-HT1AR, SERT, MAO-A,MAO-B in primary hippocampal neurons. RESULTS: The MAO-A expression in primary cultured hippocampal neurons of model rat serum were significantly increased(P<0.05), 5-HT1AR and SERT expression was significantly decreased(P<0.05) , while MAO-B expression was not significantly different. 5-HT1AR, SERT,MAO-A expression in primary cultured hippocampal neurons was tended to be normal in rats treated with Jingqianshu. CONCLUSION: The occurrence of liver-qi depression syndrome is related to the abnormal expression of MAO-A, SERT and 5-HT1AR in hippocampal neurons , which may be the micro-mechanism of PMS liver-qi depression syndrome onset.%目的:研究经前期综合征(PMS)肝气郁证大鼠血清对大鼠原代海马神经元的5-羟色胺1A受体(5-HT1AR)信号转导通路相关基因5-羟色胺转运蛋白(SERT)、单胺氧化酶(MAO) -A、MAO-B表达的影响.方法:采用慢性束缚应激法复制PMS肝气郁证大鼠模型;高效液相色谱(HPLC)法检测血清中5-HT的含量;运用RT-PCR半定量和Western blot法检测正常、模型、经前舒干预大鼠的血清对海马神经元中5-HT1AR、SERT、MAO-A、MAO-B表达的影响.结果:加入模型大鼠血清的大鼠海马原代神经细胞中MAO-A表达较正常大鼠显著升高(P<0.05),5-HT1AR、SERT表达显著降低(P<0.05),MAO-B表达无显著性差异.而加入经前舒干预大鼠血清后,5-HT1AR、SERT、MAO-A表达均趋于正常.结论:PMS肝气郁证的发生

  18. 河北临漳县邺城遗址东魏北齐佛寺塔基的发现与发掘%Discovery and Excavation of the Pagoda Foundation Vestiges in the Buddhist Temple of the Eastern Qi and Northern Wei period on the Yecheng City-site in Linzhang County, Hebei

    Institute of Scientific and Technical Information of China (English)

    中国社会科学院考古研究所邺城考古队; 河北省文物研究所邺城考古队

    2003-01-01

    The pagoda-foundation vestiges of the Buddhist temple on the southern Yecheng city-site were discovered about 200m southwest of Zhaopengcheng village in Xiwen Township, Linzhang County. They lie some 1300m to the south of the southern wall of southern Yecheng City and to the east of the line extended from thecentral axis of the southern Yecheng City and Zhumingmen-gate Road. Judging from the stratigraphical evidence and objects unearthed, the rammed earth of the pagoda foundations goes back to the Eastern Wei and Northern Qiperiod. The vestiges revealed include remains of the pagoda body above the ground and those of the foundation ex-cavations under the ground. The pagoda body can be inferred to be square, with the sides measuring about 30m.This is the only ruined square wooden Buddhist pagoda of the Eastern Wei and Northern Qi period discovered so far in China.

  19. 基于“体质-疾病谱-主症”模式的黄芪桂枝五物汤方证规范化文献研究%Formula Syndrome Standardization Study of Classical Formula of Huang-Qi-Gui-Zhi-Wu-Wu Decoction Based on Mode of "Constitution-Spectrum of Disease-Main Symptom" on Document Data

    Institute of Scientific and Technical Information of China (English)

    刘晓丽; 周美启; 李锋刚; 郜峦; 陆翔; 李净; 吴元洁

    2013-01-01

    Objective:It is to study the formula syndrome rule of Classical formula of Huang-qi-gui-zhi-wu-wu decoction on relative document data based on the mode of constitution-spectrum of disease-main symptom.Methods:By collecting,sorting out the individual clinical cases,then analysis and data mining of them.Results:Constitution and appearance of its formula syndrome are lack of vitality and fatigue,chills,lack of energy even to speak,lusterless or sallow complexion.Diseases mainly treated are neuritis,postpartum disease,Raynaud's disease,cervical vertebra disease,urticaria.Differentiation syndromes are syndrome of meridian obstruction and defense-qi and nutrient blood deficiency,Qi deficiency and blood stasis syndrome owing to yang deficiency,blood stasis syndrome complicated cold coagulation.Main symptoms include pain,numbness,swelling,sweating,dizziness,etc.Pulses mostly are sinking and thin or thin and weak or sinking and weak.Tongue color is pale white or pink and tongue coats are thin white or white mainly.Among this formula,common dosage of Astragalus is higher than other medicinal,and maximum dosage of stragalus and jujube are significantly higher than other medicinal.Chinese angelica,licorice,spatholobus stem,Rhizoma ligustici wallichii are frequently be added.Conclusion:Formula syndrome of Huang-qi-gui-zhi-wu-wu decoction includes the constitution and appearance and main symptom characteristics attending to the diseases above mentioned.Based on the original formula,other medicinal are added accordingly promoting blood circulation to remove blood staais,tonifying deficiency,releasing the exterior,dispelling wind and dampness,calming the liver to stop the wind.%在“体质-疾病谱-主症”模式下,通过对黄芪桂枝五物汤个案的搜集整理分析与数据挖掘,从文献角度探讨该方的方证规律.结果显示该方证体质及体貌特征为神疲乏力、畏寒、少气懒言、面色无华或萎黄等;所治疾病以神经炎、产后病

  20. Research on Urine Metabolomics of HIV/AIDS Patients with Spleen-lung Qi-deifciency Based on H-NMR Technique%基于氢核磁共振技术HIV/AIDS肺脾气虚证患者尿液代谢组学研究

    Institute of Scientific and Technical Information of China (English)

    许前磊; 温冠晓; 王娟; 谢世平; 马素娜; 张宁; 刘伟; 崔永霞

    2015-01-01

    This study was aimed to explore the characteristics of urine metabolomics among HIV/AIDS patients with spleen-lung qi-deficiency. H-NMR technique was combined with principal component analysis and cluster analysis in the comparison of urine metabolic products among 24 HIV/AIDS cases with spleen-lung qi-deficiency and 20 healthy control cases. The results showed that urine metabolic products of HIV/AIDS patients with spleen-lung qi-deficiency and healthy people by H-NMR technique detection and PLS-DA analysis can classify the outline of urine metabolites. There were about 20 variables in the difference between two groups. The speculated substances contained glycyl-L-leucine, L-valine, α-aminobutyric acid, methyl succinic acid, glycine propionyl, and etc. It was concluded that H-NMR technique was able to classify the outline of urine metabolites between HIV/AIDS cases with spleen-lung qi-deficiency and healthy people. Part of the potential existed characteristic markers contributed to the clinical diagnosis of traditional Chinese medicine (TCM) syndrome differentiation of AIDS. It had certain effect in its quantitative analysis.%目的:探讨HIV/AIDS肺脾气虚证尿液的代谢组学特征。方法:采用氢核磁共振技术结合主成分分析、聚类分析方法比较24 例HIV/AIDS 肺脾气虚证和20 例健康对照组的尿液代谢产物的差异。结果:氢核磁共振技术检测的HIV/AIDS 肺脾气虚证患者与健康人尿液代谢物经PLS-DA 分析后,代谢物轮廓可以分开;两组间差异性的变量约20 个,大概推测为以下物质:甘氨酰-L- 亮氨酸、L- 缬氨酸、α- 氨基丁酸、甲基丁二酸、丙酰甘氨酸等。结论:运用氢核磁共振技术可以将HIV/AIDS 肺脾气虚证和健康人尿液代谢产物轮廓进行区分。部分可能存在的潜在特征性标志物有助于艾滋病中医证候的临床诊断,对其量化分析有一定的作用。

  1. 梁启超的人格思想对塑造大学生健全人格的启示%ENLIGHTENMENT ON THE FORMING OF COLLEGE STUDENT'S SOUND PERSONALITY BASED ON LIANG QI-CI-IAO'S PERSONALITY THOUGHT

    Institute of Scientific and Technical Information of China (English)

    冯慧娟

    2012-01-01

    人格教育是高等学校进行素质教育的一个重要组成部分。近代启蒙思想家梁启超明确提出了人格完善的三要素,指出知、情、意三件具备才能成为一个人,他的人格思想对于当代大学生健全人格的塑造具有重要的启示。%Personality education is a major part of quality education at university. LIANG Qi - chao, as a pioneer in modern China en- lightenment movement, proposed that three factors: intelligence, emotion and willpower may contribute to a complete personality, and a man with them may become a true person. His personality thought exerts great inspirations on the forming of the complete personality of college students.

  2. 5-HTR1A 基因在经前期综合征肝气郁证模型大鼠下丘脑区的表达%Expression of 5-HTR1A in Hypothalamus of Pre-Menstrual Syndrome Liver-qi Depression Model Rats

    Institute of Scientific and Technical Information of China (English)

    徐凯勇; 高杰; 宋春红; 李自发; 魏盛; 张惠云

    2012-01-01

    Objective To investigate the pathogenesis and drug target through the study about expression of 5-HTR1A in the hypothalamus of Pre-Menstrual Syndrome (PMS) Liver-qi Depression Model Rats. Methods The PMS Liver-qi Depression model was established by bounding the rat's feet, Then it was divided into control group, model group and treated group which were treated with Jingqianshu pellet. The mRNA and protein expressions of 5-HTR1A in the hypothalamus of the model Rats were detected by RT-PCR and Western Blotting separately. The data were analyzed by the one-way ANOVA and LSD with the software SPSS 16.0. Results The mRNA and protein expressions of 5-HTR1A in the hypothalamus of model group were decreased significantly compared with the control group. And the expressions of the treated group with Jingqianshu pellet were increased significantly compared with the model group. But there were no significant difference between the treated and the control groups. Conclusion The expressions of 5-HTR1A in the hypothalamus of PMS Liver-qi Depression Model Rats were decreased significantly compared with the control rats, and then the expressions level could recovered to the control level after treated with Jingqianshu pellet. Therefore, it was demonstrated that the expression of 5-HTR1A and PMS Liver-qi Depression may related, and the gene could be the drug target of Jingqianshu granule.%目的 通过研究5-羟色胺受体1A (5-HTR1A)基因在经前期综合征(PMS)肝气郁证模型大鼠下丘脑区的表达,探讨该证的发病机制及药物作用靶点.方法 束缚法制备PMS肝气郁证模型大鼠,经前舒颗粒干预,获得正常组、造模组、给药组;运用RT-PCR和Western Blotting方法检测大鼠下丘脑区5-HTR1A mRNA及其蛋白表达;应用软件SPSS 16.0,通过单因素方差分析及LSD法统计数据.结果 PMS肝气郁证模型组大鼠与正常组相比,下丘脑5-HTR1A mRNA及蛋白表达均显著降低;经前舒颗粒给药后与造模组相比,

  3. 益气法对老年呼吸衰竭患者撤机影响的临床研究%Clinical Study of the Effect of Supplementing Qi Method on Weaning from Mechanical Ventilation in Elderly Patients with Respiratory Failure

    Institute of Scientific and Technical Information of China (English)

    聂卫群; 俞兴群; 洪峰; 高志凌; 王龙梅; 李远思

    2013-01-01

    Objective :To observe the effect of Supplementing Qi combined with conventional weaning from mechanical ventilation in elderly patients with respiratory failure .Methods :32 elderly patients with respiratory failure who meeting the conditions of weaning from mechanical ventilation were chosen ,and randomly divided into the treatment group (16 cases) and the control group (16 cases) .The control group were given by the conventional weaning from mechanical ventilation ,while the treatment group were given by Supplementing Qi on the basis of conventional weaning from me-chanical ventilation .The patients with deficiency of both Qi and Yin ,who were treated with Shenmai injection ,while Yang deficiency patients were treated with Shenfu injection ,50ml injection by intravenous drip ,two times a day (bid) , 7~10 days for a course of treatment .The clinical effects were compared between the two groups .the weaning time of success cases were compared ,and arterial blood gas analysis were observed before and after weaning from mechanical ventilation .Results:In the treatment group ,the success rate of weaning was higher than that of the control group ,me-chanical ventilation rate again in 48h and the mortality rate were lower than those of the control group (P<0 .05);for the two groups of weaning success cases ,arterial partial pressure of oxygen in the treatment group after weaning was higher than that of the control group ,and the weaning time shorter than the control group (P<0 .05) .Conclusion:Sup-plementing Qi combined with conventional weaning from mechanical ventilation could improve arterial partial pressure of oxygen and oxygenation ,could shorten the weaning time in elderly patients with respiratory failure ,improve the suc-cess rate of weaning ,and reduce the mortality rate .%目的:观察益气法联合常规撤机方式对老年呼吸衰竭患者撤机的影响。方法:选择符合撤机条件的老年呼吸衰竭患者32例,随机分为治疗组与对

  4. The effect of sVEGF of Huang-qi injection combined with TEC chemotherapy in treatment of breast cancer%黄芪注射液联合TEC化疗方案对乳腺癌患者血清VEGF的影响

    Institute of Scientific and Technical Information of China (English)

    王周权; 王学良

    2011-01-01

    目的:观察黄芪注射液配合TEC方案(多西紫杉醇、表阿霉素、环磷酰胺)治疗对乳腺癌患者血清血管内皮生长因子(sVEGF)水平及全身不良反应的影响.方法:将59例原发性乳腺癌随机分为单纯TEC方案组(Ⅰ组 29例)和黄芪注射液+TEC方案组(Ⅱ组,30例),对两组患者的sVEGF表达情况及全身不良反应进行比较.结果:Ⅱ组治疗后患者sVEGF水平,不仅低于治疗前,而且低于Ⅰ组,有显著性差异(P<0.05);Ⅱ组患者生活质量明显提高,两组比较有显著性差异(P<0.05);Ⅱ组化疗不良反应低于Ⅰ组,两组比较有显著性差异(P<0.05).结论:黄芪注射液联合TEC化疗方案治疗乳腺癌,能明显降低患者血清中VEGF的浓度,减轻化疗不良反应,从而使患者的生活质量得到改善.%Objective:To observe the effect of Huang - qi injection and TEC chemo - therapy on sVEGF in treatment of breast cancer. Methods: Total of 59 patients with breast cancer were divided into 2 groups: Group Ⅰ( TEC chemotherapy group,29 ),Group II( Huang - qi + TEC chemotherapy group,30 ). Serum vascular endothelial growth factor ( sVEGF )level was detected by sandwich ABC enzyme linked immunosorbant assay before and after treatment. Results: There was no significant difference between Group I and Group Ⅱ ( P >0. 05 ) before treatment in sVEGF levels. After treatment the sVEGF level was significant lower than pre - treatment in group Ⅱ ( P = 0. 046 ). The level of sVEGF was slightly lower than pretreatment but no statistic difference( P >0. 05 ). Furthermore, the level of sVEGF in group Ⅱ was significantly lower than that of group Ⅰ ( P =0. 034 ). The effective rates of leucopenia suppression in Group I was 100% and in Group II was 93. 3% . The effective rates of Ⅲ +Ⅳ leucopenia suppression in group I and group Ⅱ were 62. 1% and 36. 6% ,P <0. 05,the effective rates of Ⅲ+ Ⅳ gastrointestinal reaction in Group I and Group Ⅱ were 51.7% and 16. 7% ,P

  5. Clinical experience on 72 cases with Qi-blood deficiency type osteoporosis in the treatment of self-made Yi Xue Qiang Gu decoction%自拟益血强骨汤治疗气血亏虚型骨质疏松症72例临床体会

    Institute of Scientific and Technical Information of China (English)

    宋雪; 杨大伟; 万家兴

    2015-01-01

    目的:探讨自拟益血强骨汤治疗气血亏虚型骨质疏松症的临床疗效.方法:2010年1月-2012年6月采用自拟益血强骨汤结合阿仑膦酸钠治疗气血亏虚型骨质疏松症患者 72 例,观察疗效、中医证候及骨密度的变化.结果:疗效评定有效率93.1%,中医证候评定有效率90%,骨密度评定有效率87.5%.结论:自拟益血强骨汤能显著改善气血亏虚型骨质疏松症患者的症状,增强患者骨质,值得临床推广.%Objective:To investigate the clinical effect of self-made Yi Xue Qiang Gu decoction in the treatment of blood deficiency type of osteoporosis.Methods:72 patients with Qi-blood deficiency type osteoporosis were selected from January 2010 to June 2012,and all of them were treated with self-made Yi Xue Qiang Gu decoction combined with alendronate sodium.Then we observed the curative effect,the changes on TCM syndromes and bone mineral density.Results:The efficacy evaluation of efficiency was 93.1% ;evaluation efficiency of TCM syndrome was 90% ;the bone density assessment efficiency was 87.5% . Conclusion:Self-made Yi Xue Qiang Gu decoction in the treatment of Qi-blood deficiency type osteoporosis can improve the patient's symptoms and enhance the patient's bone,so it is a good treatment method,and worthy of clinical application.

  6. 槐杞黄干预小鼠IgA肾病模型的疗效观察以及机制探讨%Clinical Observation on Immunity Nephritis Model Mouse Treated by Huai Qi Huang and Related Analysis of Mechanism

    Institute of Scientific and Technical Information of China (English)

    王紫; 陈瑜; 罗军; 周建华

    2011-01-01

    Objective: Clinical observation on immunity nephritis model mouse treated by Huai Qi Huang and related analysis of mechanism. Methods: Female BABL/c mouse were divided into three groups: normal control group, IgA nephropathy model group and Huai Qi Huang treatment group. The number of every group was equal ( n = 10 ). The mouse from model group and Huai Qi Huang treated group were treated with bovine serum albumin by gastric - perfusion, injected with bovine serum albumin and staphylo-coccal enterotoxin Through the tail wein in order to establish IgA nephropathy model,normal control group were treated with acidified water by gastric - perfusion, injected with phosphate buffer Through the tail wein as control. Huai Qi Huang treated group were treated with Huai Qi Huang ( 4 g/kg ) by gastric - perfusion every day after eight weeks, normal control group and IgA nephropathy group were treated with equal volume of saline by gastric - perfusion every day as control. Twenty - four hours urinary protein excretion, serum biochemical value such as albumin, urea nitrogen, creatinine and pathological changes of kidney, were examined. All mouse were harvested at the 12 th week, The splenic lymphocytes were prepared by aseptic technique. The cell suspention were inoculated in 24 - well flat - bottom plates unde37 °C ,50 ml/L C02 , 2. 5 |Jig/L COnA fter 51 h, and the supernatants were harvested for the detection of IL -2^IL -4^INF - 7 by ELISA,compare the ratio of INF - y/ IL -4 among every group. With ELISA method to detect the total IgA concentration in serum among every group. Results: 1 ) The twenty - four hours urinary protein exceretion was higher in model and Huai Qi Huang treatment group than that in control group from 8th week to 12th week( P 0. 05 ),four weeks after treatment, the twenty - four hours urinary protein exceretion in huai er group was lower than in model group( P 0.05),治疗4周后,槐杞黄治疗组24 h尿蛋白较模型组明显降低(P<0.05);2)实验

  7. STUDY ON COORDINATION DEVELOPMENT OF BETWEEN REGIONAL DEVELOPMENT AND ECO-ENVIRONMENT IN HA-DA-QI INDUSTRIAL CORRIDOR%哈大齐工业走廊区域开发与生态环境协调发展研究

    Institute of Scientific and Technical Information of China (English)

    万鲁河; 张茜; 陈晓红

    2011-01-01

    The research area of this paper is Ha-Da-Qi Industrial Corridor, which is a typical point-axis development area. By the supporting of the evaluation index system and fuzzy mathematics, this paper establishes coordination degree model, and analyzing the coordination degree between soci-economy and eco-environment in Ha-Da-Qi Industrial Corridor. To explore the impact factors of the coordination degree between soci-economy and eco-environment, and disassembling the relationship between indicators of soci-economy and eco-environment. Through a series of analyses, this study illustrates that, the coordination degree of Ha-Da-Qi Industrial Corridor shows phase change characteristics, the coordination degree of Harbin and Daqing has undergone threes stages, namely the up-down-up, and Qiqihar undergone only a first upward then downward two stages; except the coordination degree between soci-economy and coo-environment of Harbin is belonging to endangered disharmony in 2006, the other is belong to coordination type; the effect of soci-economy index to eco-environment development level of Ha-Da-Qi is different, which are the most effected indexes of Ha-Da-Qi in order: the actual utilization of foreign capital, the retail total of social consumption goods growth rates and the large industrial enterprises consumption of crude oil, and the effect of eco-environment index to soci-economy development level is also different, which are the most effected indexes in order: industrial exhaust gas emissions, traffic noise average and industrial waste water quantity of emission standard, consequently, in order to coordinately develop the soci-economy and eco-environment in Ha-Da-Qi Industrial Corridor, that should pertinently adjust these aspects.%将点轴开发的典型地区——哈大齐工业走廊作为研究区域,在指标体系构建和模糊数学理论的支持下,建立协调度模型,深入分析哈大齐工业走廊社会经济与生态环

  8. 六君丹参颗粒治疗气虚痰瘀型高血压合并颈动脉硬化临床研究%Clinical Study of Liujun Danshen Granules in Treating Hypertension Combined with Carotid Atherosclerosis of Qi-deficiency and Phlegm-blood Stasis Syndrome

    Institute of Scientific and Technical Information of China (English)

    黄琳; 吴永刚; 李博; 张珍珍; 黄汉超

    2012-01-01

    Objective To observe the intervention effect of Liujun Danshen Granules on clinical symptoms, carotid intima, blood lipid and related factors of patients with hypertension combined with carotid atherosclerosis of qi-deficiency and phlegm-blood stasis syndrome. Methods With randomized controlled method, 124 patients of hypertension combined with carotid atherosclerosis of qi-deficiency and phlegm-blood stasis syndrome were divided into the treatment group (64 cases) and the control group (60 cases). The control group was given the conventional treatments of lowering blood pressure and cholesterol, the treatment group was given Liujun Danshen Granules additionally. The treatment course was six months. By observing the changes of clinical symptoms integral, carotid intima-media thickness (IMT), plaques number, blood lipid, blood fibrinogen and other laboratory indexes of the two groups before and after treatment, the clinical effect of Liujun Danshen Granules was evaluated. Results Compared with the control group, the effects on clinical symptoms such as weakness, IMT of left common carotid artery, left common carotid artery bifurcation and left internal carotid artery, the whole blood viscosity and plasma viscosity, and TC of the treatment group were significant. Conclusion For patients of hypertension combined with carotid atherosclerosis of qi-deficiency and phlegm-blood stasis syndrome, Liujun Danshen Granules can improve the clinical symptoms, reduce the carotid intima thickness to treat carotid atherosclerosis, and lower blood lipid.%目的 采用中药六君丹参颗粒治疗高血压合并颈动脉硬化属气虚痰瘀型患者,观察其对临床症状、颈动脉内膜及血脂等相关因子的干预效果.方法 采取随机对照的方法,将124例临床辨证为气虚痰瘀型高血压合并颈动脉硬化患者分为治疗组64例、对照组60例.对照组采用常规降压和降脂治疗,治疗组在对照组基础上加用六君丹参颗粒治疗,2

  9. Effect of QiHe Quzhi prescription on leptin and sex hormone in non-alcoholic fatty liver disease patients%杞荷祛脂方对非酒精性脂肪性肝病患者血清瘦素及性激素影响的研究

    Institute of Scientific and Technical Information of China (English)

    沈震; 费新应; 刘文涛; 邵志林; 陈炎生

    2014-01-01

    目的:研究血清瘦素( LEP)、性激素与非酒精性脂肪性肝病( NAFLD)相关指标的关系,探讨杞荷祛脂方的疗效作用机制。方法:80例NAFLD患者随机分为A、 B两组,每组各40例,另40例健康志愿者作为对照组(C组)。 A组患者予杞荷祛脂方, B组患者口服水飞蓟宾胶囊,比较3组人员的临床、生化指标及瘦素、性激素水平。结果:①与C组比较, A、 B两组患者的LEP、雌二醇水平较高,总睾酮水平较低。血清LEP、雌二醇水平与NAFLD相关指标呈正相关,总睾酮与之呈负相关( P<0.01或P<0.05)。②与治疗前比较,治疗后A、 B两组患者血清瘦素水平降低,差异有显著性意义(P<0.05);与B组比较, A组患者治疗后血清LEP更低(P<0.01)。无论是治疗前和治疗后, A、 B两组患者雌二醇及总睾酮无明显改变(P>0.05)。结论:杞荷祛脂方对NAFLD患者高血清瘦素水平有明显的调节作用,而对血清性激素无明显影响。%Objective: To evaluate the relationship between serum leptin ( LEP) and sex hormone related indexes of nonal-coholic fatty liver disease ( NAFLD) , and observe the effect of Qi He Quzhi prescription on serum LEP and sex hormone levels in patients with NAFLD.Methods: Eighty cases of NAFLD patients were randomly divided into group A and group B, another 40 healthy volunteers as control group ( group C) .Group A was treated by Qi He Quzhi prescription, group B was given silibinin capsules, recording all of clinical and biochemical indexes.Results: ①Compared with group C, the LEP and estradiol levels of group A and B were more higher, total testosterone level was more lower.The high serum LEP, estradiol levels were positive re-lated to the NAFLD relationship indexs, but total testosterone no negative related to it (P0.05) .Conclusion: Qi He Quzhi prescription has obvious regulating effect on serum LEP but sex hormone in NAFLD

  10. 308例骨密度结果及与"肾虚、气虚、血瘀证"相关性的分析%The correlation analysis between bone mineral density and the syndromes of kidney deficiency, qi deficiency, and blood stasis in 308 cases

    Institute of Scientific and Technical Information of China (English)

    王国栋; 莫文

    2011-01-01

    Objective To explore the relationship between the T score of bone mineral density (BMD) and the syndromes of kidney deficiency, qi deficiency, and blood stasis; and to provide scientific basis for the treatment of osteoporosis with traditional Chinese medicine.Methods Patients were collected from BMD examiners at the Shanghai University of Traditional Chinese Medicine, Longhua Hospital, from August 2010 to February 2011.The objects were screened.BMD was measured and recorded.The collected data were analyzed statistically.Results 1 ) T-Score continuously decreased with age growing, and the T-Scores in different age groups were significantly different ( P < 0.01 ).2 ) The linear correlation analysis showed that the T-Score was positively correlated with the height, weight, and BMI (P < 0.01 ).3) The bone mass in patients with or without kidney deficiency, qi deficiency, or blood stasis was significantly different (P <0.01).Conclusion T-Score is correlated with age, height, weight, BMI, kidney deficiency, qi deficiency, and blood stasis.The results obtained in this study provide reference for clinical and epidemiological study for osteoporosis treatment with Chinese medicine.%目的 探讨肾虚证、气虚证、血瘀证与骨密度T值的关系,为骨质疏松症的中医诊治提供科学依据.方法 收集2010年8月~2011年2月期间在上海中医药大学附属龙华医院骨密度室检查者,筛选符合条件的对象,测量其骨密度,并填写骨密度记录表,对收集的数据进行统计分析.结果 1.随着年龄的增长,T值不断降低,且不同年龄组T值有显著差异(P<0.01);2.根据直线相关分析显示.T值与身高、体重、BMI均呈正相关(P<0.01);3.有肾虚证表现者与无肾虚证表现者、有气虚证表现者与无气虚证表现者、有血瘀证表现者与无血瘀证表现者的骨量情况差异有统计学意义(P<0.01).结论 T值与年龄、身高、体重、BMI、肾虚证、气虚证、血瘀证有相

  11. 奇正青鹏膏外敷配合推拿手法治疗30例肱骨外上髁炎临床疗效观察%Efficacy of QI ZHENG QING Peng Plaster and Massage Manipulation in Treating 30 Patients with Humeral Epicondylitis

    Institute of Scientific and Technical Information of China (English)

    刘红艳

    2013-01-01

    目的观察奇正青鹏膏配合推拿手法治疗肱骨外上髁炎治疗效果。方法将30例36肘随机分为两组,治疗组15例18肘,取2g左右青鹏膏涂于外侧髁压痛点区域,点按曲池、手三里、合谷,然后自肱骨外侧髁沿桡侧腕伸肌和指总伸肌腱走向反复推揉弹拨3min,放松肌肉直至药剂透皮吸收(不粘手为准),每天早晚2次治疗4w。对照组15例18肘,选用醋酸曲安奈德针20mg溶于2%利多卡因2.5ml,注射点选择外上髁前下方痛点周围区域,1次/w,共4w。4w后评定VAS评分及疗效。结果两组治疗结果经统计学检验P<0.05,治疗组疗效优于对照组,VAS评分降低更多,有显著性差异。结论奇正青鹏膏剂外敷配合推拿手法治疗肱骨外上髁炎方法简单,疗效显著,不良作用小,患者依从性好,值得临床推广使用。%Objective To observe the ef ect of QI ZHENG Qing Peng paste and massage manipulation treatment of humeral epicondylitis. Methods 30 patients (36 elbows) with humeral epicondylitis were randomized into two groups,15 patients (18 elbows) treated with QI ZHENG Qing Peng paste and massage manipulation, take 2 grams Qing Peng cream applied to the region of the lateral condyle of tender points, tap Qu CHI, SHOU SANLI, Hegu, Ashi xue,then from the lateral humeral condyle along the radial side of the wrist extensor and refers to the total extensor tendon towards repeated push, rub, fingerstyle and toggle for 3 minutes, relax the muscles until the pharmaceutical transdermal absorption (sticky prevail),twice a day (morning and evening) , for four weeks. 15 patients (18 elbows)in the control group,treated with triamcinolone acetonide needle 20mg dissolved in 2% lidocaine 2.5ml external condyle pain points below the area around the injection point selection, once a week for 4 weeks. The dif erence between VAS score and ef icacy were for statistical analysis after 4 weeks. Results Compared with control

  12. 长春西汀联合益气聪明汤治疗TCD异常突发性聋的疗效观察%Analysis on the effectiveness of vinpocetine combined with Qi-Replenishing Sharp and Bright Decoction in treating sudden deafness with abnormal transcranial Doppler (TCD)

    Institute of Scientific and Technical Information of China (English)

    陈玉卿; 孙宣东; 邹嘉平

    2013-01-01

    Objective To evaluate the efficacy of vinpocetine combined with Qi-Replenishing Sharp and Bright Decoction in treating sudden deafness with abnormal transcranial Doppler(TCD).Methods 100 cases of sudden deafness were randomly selected and divided into two groups.Both groups were given the treatment of adenosin e disodiun,hormones,hyperbaric oxygen,B group vitamins and other treatment.One group received intravenous drop of vinpocetine (control group) and the other received vinpocetine combined with Qi-Replenishing Sharp and Bright Decoction (observation group).The therapeutic efficacies of the two groups were evaluated by the changes of frequency of hearing threshold and TCD.Results The total effective rate of hearing improvement in sudden deafness was higher (88%) in observation group compared with control group (72%)(P<0.05).The change of average flow velocity of vertebral basilar artery in TCD proved that observation group had better effects than control group,which had statistical difference.Conclusion The study reveals a good effectiveness of vinpocetine combined with QiReplenishing Sharp and Bright Decoction in treating sudden deafness with abnormal TCD,its wide use should be clinically recommended.%目的 探讨长春西汀联合益气聪明汤治疗对经颅多普勒(TCD)检测异常的突发性聋的疗效.方法 将100例TCD异常的突发性聋患者随机分成联合治疗组和长春西汀组,两组均常规行能量合剂、激素、高压氧、R族维生素等治疗,联合冶疗组给予长春西汀静脉滴注以及益气聪明汤口服,长春西汀组给予长春西汀静脉滴注,观察对耳聋的疗效及TCD用药前后变化情况,评价长春西汀联合益气聪明汤治疗TCD异常突发性聋的疗效.结果 电测听结果显示,治疗后联合治疗组有效率88%,长春西汀组有效率72%,两组疗效比较,差异有统计学意义(P<0.05).TCD结果显示联合治疗组在治疗后椎-基底动脉平均血流流速较

  13. 健身“六字诀”结合益气活血法促进COPD稳定期患者肺康复的临床研究%Clinical Research of the Effects of "Six-Character Formula" of Physical Exercise Combined with Method of Benefiting Qi and Activating Blood on the Lung Rehabilitation in COPD in Stable Phase

    Institute of Scientific and Technical Information of China (English)

    陈红英; 彭磊; 范毕辉; 陆剑豪

    2016-01-01

    目的:观察健身“六字诀”结合益气活血法促进慢性阻塞性肺疾病(chronic obstructive pulmonary disease,COPD)稳定期患者肺康复的临床疗效.方法:选取2014年1月-2015年1月于本院就诊的COPD稳定期患者67例,随机分为对照组34例和治疗组33例,对照组采用常规治疗及康复方法,治疗组在对照组治疗的基础上采用健身“六字诀”结合益气活血法肺康复锻炼,两组疗程均为6个月,观察两组患者临床疗效.结果:两组患者AECOPD发作次数均有所减少,治疗组减少幅度明显大于对照组,差异具有显著性(P<0.05);治疗组在治疗后FVC、FEV1 pred%均较治疗前升高,差异有统计学意义(P<0.05),但FEV1/FVC与对照组比较无显著统计学差异(P>0.05).治疗组治疗后CAT、mMRC评分以及焦虑抑郁状态评分均明显下降,差异具有统计学意义(P<0.05).结论:“六字诀”结合益气活血法能减少COPD的急性发作次数、改善肺通气功能水平、改善心理状态和生活质量,从而为COPD的社区康复治疗提供更为广阔的思路.%Objective:To observe the clinical effects of " Six-Character Formula" of physical exercise combined with method of benefiting qi and activating blood on the lung rehabilitation in COPD in stable phase.Methods:Totally 67 patients with COPD in stable phase hospitalized between January,2014 and January,2015 were randomized into control group and treatment group,with 34 cases in each group.Control group were given conventional treatment and rehabilitation therapy while treatment group were additionally performed "Six-Character Formula" of physical exercise combined with method of benefiting qi and activating blood.The treatment course for both groups was 6 months.The clinical effects of both groups were observed.Results:The occurrence times of AECOPD in both groups declined and the decline in treatment group was greatly greater than that in control group;the difference had

  14. Herniation Surgery and the Change of Infrared Thermal Image Therapeutic Observation of Qi-guiding Needling plus Electroacupuncture for Intractable Low Back Pain after Lumbar Disc%导气针法配合电针治疗腰突症术后顽固性腰痛疗效观察及红外热像变化

    Institute of Scientific and Technical Information of China (English)

    竺永达; 张峻峰; 吴耀持

    2016-01-01

    Objective To observe the clinical efficacy of qi-guiding needling plus electroacupuncture in treating intractable low back pain after lumbar disc herniation surgery and the change of infrared thermal image.Method Totally 172 patients with intractable low back pain after lumbar disc herniation surgery were randomized into a treatment group and a control group, 86 cases in each group. The treatment group was intervened by qi-guiding needling plus electroacupuncture, while the control group was by electroacupuncture alone. The infrared thermal image of the affected low back area was observed before and after intervention, and the clinical efficacies were compared between the two groups.Result The change of infrared thermal image of the affected low back area in the treatment group after intervention was significantly different from that in the control group (P<0.01). The total effective rate and the recovery-markedly-effective rate were respectively 87.2% and 66.3% in the treatment group, versus 74.4% and 37.2% in the control group, and the differences were statistically significant (P<0.05,P<0.01).Conclusion Qi-guiding needling plus electroacupuncture can mitigate the intractable low back pain after lumbar disc herniation surgery.%目的:观察导气针法配合电针治疗腰椎间盘突出症术后顽固性腰痛的临床疗效及红外热像变化。方法将172例腰椎间盘突出症术后出现顽固性腰痛患者随机分为治疗组和对照组,每组86例。治疗组采用导气针法配合电针治疗,对照组采用单纯电针治疗。观察两组治疗前后腰痛部位红外热像变化情况,比较两组临床疗效。结果治疗组治疗前后腰痛部位红外热像图温度差值与对照组比较,差异具有统计学意义(P<0.01)。治疗组总有效率和愈显率分别为87.2%和66.3%,对照组分别为74.4%和37.2%,两组比较差异均具有统计学意义(P<0.05,P<0.01)。结论导气针法配合电针能缓解

  15. Clinical Efficacy of Strong Stimulation of Acupuncture in the Treatment of Tinnitus of Liver Qi Stagnation Pattern/Syndrome%强刺激针刺手法治疗肝气郁结型耳鸣的临床疗效研究

    Institute of Scientific and Technical Information of China (English)

    石磊; 冷辉; 李媛; 孙海波; 郭庆革

    2016-01-01

    Objective To observe the clinical efficacy of the strong stimulation of acupuncture on tinnitus of liver qi stagnation pattern/ syndrome. Methods Three hundred and eighty - four patients of tinni-tus of liver qi stagnation pattern/ syndrome were randomized into a treatment group(192 cases)and a control group(192 cases). In the treatment group,the strong acupuncture stimulation was used. In the control group, the conventional acupuncture was applied. Before and after treatment,the scores of tinnitus handicap assess-ment table(THI)and the Hamilton depression scale(HAMA)were observed in the two groups. Results The degree of tinnitus and THI and HAMA scores in the treatment group were lower apparently than those in the control group,indicating the significant difference(P ﹤ 0. 05). After treatment,the emotion score and function score in the treatment group were apparently better than those in the control group,indicating the significant difference(P ﹤ 0. 05). The difference in the severity score was not significant after treatment in the two groups(P ﹥ 0. 05). The total remarkably effective rate in the treatment group was apparently higher than that in the control group,indicating the significant difference(P ﹤ 0. 05). Conclusion The strong acupuncture stimulation achieves the good clinical effect on tinnitus of liver qi stagnation pattern/ syndrome. This acupunc-ture technique relieves anxiety,and improves sleep quality and this technique is worthy to be promoted in ac-upuncture treatment.%目的:观察强刺激针刺手法治疗肝气郁结型耳鸣的临床疗效。方法选取384例肝气郁结型耳鸣患者,将其随机分为治疗组(192例)、对照组(192例),治疗组患者针刺疗法采取强刺激行针手法,对照组采用常规针刺方法,观察两组治疗前后耳鸣残疾评估量表( THI)及汉密尔顿焦虑量表积分变化。结果治疗组患者的耳鸣程度、THI 及汉密尔顿焦虑量表评分均均明显

  16. Effect of kidney tonifying prescription intervention the level of sex hormones related regulating factors of elderly hypertension kidney-qi deficiency syndrome%补肾方药对老年高血压病肾气亏虚证患者性激素相关调控因子的干预作用

    Institute of Scientific and Technical Information of China (English)

    于杰; 张磊; 郭伟星

    2015-01-01

    目的:对老年高血压病肾气亏虚证患者经益肾降压方干预前后性激素相关调控因素水平进行比较。方法根据高血压病诊断与分级标准,老年高血压病肾气亏虚证量化诊断标准,选择老年高血压病肾气亏虚证患者60例,男女各半,给予益肾降压方治疗4周,采用酶联免疫吸附法检测白介素-2(IL-2)、瘦素(Leptin )、促性腺激素释放激素(GnRH)和硫酸脱氢表雄酮(DHEA-S )的水平。结果经益肾降压方干预后男性老年高血压病肾气亏虚证患者的血清Leptin和GnRH的水平有所回落,DHEA-S的水平有所回升,女性老年高血压病肾气亏虚证患者血清GnRH的水平有所回落。结论补肾方药在男性性激素相关调控因素水平上的作用靶点可能为瘦素、促性腺激素释放激素和硫酸脱氢表雄酮,女性可能为促性腺激素释放激素。%Objective This paper studies the effect of kidney tonifying prescription intervention the level of sex hormones re-lated regulating factors of elderly hypertension kidney-qi deficiency syndrome .Methods According to hypertension diagno-sis and classification standard ,TCM differentiation standard chose elder hypertension of kidney deficiency syndrome (60 cas-es ) ,half of men and women ,give kidney tonifying prescription for 4 weeks .The Elisa method was used to detect IL-2 ,Lep-tin ,GnRH and DHEA-S levels .Results After kidney tonifying prescription intervention ,the levels of Leptin and GnRH of elderly male patients with hypertension of kidney-qi deficiency syndrome declined ,the levels of DHEA-S increased .The lev-els of GnRH of elderly female patients with hypertension of kidney-qi deficiency syndrome declined .Conclusion The target of kidney tonifying prescription on sex hormones related regulating factors of elderly male patients may be Leptin ,GnRH and DHEA-S .The target of kidney tonifying prescription on sex hormones related regulating

  17. 益气养阴祛瘀中药对干燥综合征自发性模型非肥胖糖尿病小鼠的治疗作用及机制%Effects of Notifying Qi Nourish Yin and Remove Stasis Herbs on Spontaneous Models of Sjogrens Syndrome in the Non-obese Diabetic

    Institute of Scientific and Technical Information of China (English)

    王新昌; 范永升; 冯健; 曹灵勇; 谢志军; 黄继勇

    2012-01-01

    [Objective]To investigate the effects of Notifying Qi Nourish Yin and Remove Stasis herbs on Spontaneous Models of Sjogrens Syndrome in the non-obese diabetic(NOD) mice and its pharmacological mechanism.[Methods]45 female NOD mice (8-week-old) were randomly divided into three groups:Chinese medicine, hydroxychloroquine(HCQ)and normal saline(NS)group. One week later,they were administered intragastrically in Notifying Qi Nourish Yin and Remove Stasis herbs,HCQ and NS respectively, and were orally administered for 12 weeks. Three mice from each group were sacrificed at the age of 9,15 and 20 weeks.The saliva flow,serum and submandibular glands were collected at these time points.Histological changes of submandibular glands were examined by HE staining. The levels of serum IgA, IgG and C3 were detected. The expression of BAFF and NF -kB mRNA in the salivas were also detected by PT-PCR. [Results]At the end of the study, the salivary flow was significantly increased, the autoantibodies in serum, the expression of BAFF mRNA and histologjcal grading of salivary tissue were significantly lower in the Chinese medicine treatment groups(P<0.05 or 0.01). Compared with the HCQ group,the Chinese medicine group was better.[ConclusionJNotifying Qi Nourish Yin and Remove Stasis herbs can relieve the dry mouth symptom and change the pathological of salivary tissue of Sjogrens Syndrome in the NOD mice. Its mechanism may be associated with inhibition of mRNA expression of BAFF.%[目的]探讨益气养阴祛瘀中药对非肥胖糖尿病( NOD)自发性干燥综合征(SS)样小鼠的疗效及作用机制.[方法]将45只8周龄NOD自发性SS样小鼠随机分为对照组、中药组和西药组灌胃治疗12周,分别检测各组治疗前、后小鼠不同时间点(9、15和20wk)的唾液分泌量,检测各组小鼠血清的IgG、IgA、C3,比较各组小鼠颌下腺、胸腺和脾脏指数情况,并观察各组颌下腺组织病理学改变;同时采用RT-PCR法检测各

  18. 2型糖尿病气阴两虚证血清气相色谱-质谱代谢组学特点分析%Gas Chromatography-mass Spectrometry Metabolomics Features of Serum in Type 2 Diabetes Qi and Yin Deficiency

    Institute of Scientific and Technical Information of China (English)

    吴小秋; 刘志龙; 黎莉; 陈威妮; 张凰; 丁萍; 罗玉韵; 徐进华

    2014-01-01

    Through detection serum metabolomics Qi and Yin deficiency Syndrome patients of type 2 diabetes,Observe chan-ges in serum metabolites and differences with healthy group of metabolites before and after early intensive insulin therapy. Methods:The Qi and Yin deficiency in patients with type 2 diabetes will be included in the study 20 cases using intensive insulin therapy,using gas chromatography-mass spectrometry methods for treatment after metabolomics testing conducted,using principal component analysis and partial least squares discriminant analysis analysis. Results:Before and after treatment,the plasma metabolite identification,and com-pared with the healthy group,its main potential biomarkers lysophosphatidic acid,phosphatidylethanolamine,gangliosides,phosphatidyl-choline,diglycerides,cardiolipin,triglycerides,lysophosphatidy lethanolamine,phosphatidylinositol phosphate,cholesteryl decanoate,di-hydrobiopterin,Ureidosuccinic acid,and by the biological matter content and contrast logo,P < 0. 05,the difference was statistically sig-nificant. Conclusion:Qi and Yin deficiency type 2 diabetes have specific metabolic markers and have different endogenous metabolites compared with healthy controls.%目的:通过对2型糖尿病气阴两虚证患者血清进行代谢组学检测,观察早期胰岛素强化治疗前后血清代谢产物的变化及与健康组代谢产物的差别。方法:将纳入研究的2型糖尿病气阴两虚证患者20例采用胰岛素强化治疗,同时采用气相色谱-质谱联用方法进行治疗前后代谢组学检测,应用主成分分析法和偏最小二乘判别分析法进行分析。结果:治疗前后血浆代谢产物鉴定,并与健康组比较,其潜在生物标志物主要有溶血磷脂酸、磷脂酰乙醇胺、神经节苷脂、卵磷脂、二酰甘油、心磷脂、三酰甘油、溶血磷脂、磷脂酰肌醇磷酸、胆甾烯基癸酸酯、二氢生物蝶呤、脲基琥珀酸,并且经生物标志物

  19. Effective Estimation Research on Cervical Vertigo Patients with Qi Deficiency and Sputum Silting up Which were Treated by Yiqi Congming Decoction of YAN's%颜氏益气聪明汤对于颈性眩晕的疗效评价研究

    Institute of Scientific and Technical Information of China (English)

    覃小兰; 王进忠; 杨时鸿; 卢爱丽

    2012-01-01

    objective: Exploring the mechanism and application prospects of Yiqi Congming Decoction through observing its efficacy to treat cervical vertigo with Qi deficency and sputum silting up. Methods: 254cervical vertigo patients who were diagnosed by TCM of Qi deficiency and sputum silting up, and randomly divided into three groups: one group was cured with Meris-lon, the other was cured with " Yiqi Congming Decoction" , another was cured with integrate medicine. Evaluating the curative effective in nerve function score, vertigo degree, live quality and symptom scores over 14days and 3 months in three groups. Results: There were obvious differences among three groups in nerve function score, Vertigo degree, live quality and symptom scores over 14days, the integrate medicine group was superior to the western medicine group and Traditional Chinese Medicine group (P0.05). There were obvious differences among the three groups in nerve function score, vertigo degree, live quality and symptom scores over 3months. Traditional Chinese Medicine group and the integrate medicine group were superior to the western medicine group ( P0.05 ). Conclusion: It has positive effect to cervical vertigo patients with Qi deficiecy and sputum silting up which were cured with "Yiqi Congming Decoction" and Merislon, and is worth researching furthermore.%目的:通过观察颜氏益气聪明汤治疗气虚疫瘀型颈性眩晕的疗效,初步探讨该方作用机制及应用前景.方法:将254例气虚痰瘀颈性眩晕患者随机分为三组,西药组采用敏使朗治疗,中药组采用颜氏益气聪明汤治疗,中西药组在西药组治疗基础上采用颜氏益气聪明汤治疗.三组分别治疗14天,随访3个月,从神经功能评分、眩晕程度、生活质量及中医证候积分等多方面综合评价颜氏益气聪明汤疗效.结果:三组患者治疗14天后神经功能评分、眩晕程度、生活质量及中医证候积分改善比较,中西医组优于中药组、西

  20. 加味复元通气散治疗腰椎间盘突出症84例疗效观察%Clinical Observation on Treatment of 84 Cases with Lumbar Disc Herniation by Modified FuYuan TongQi Powder

    Institute of Scientific and Technical Information of China (English)

    严文有; 殷秀萍; 李有成; 张晶; 严银芳

    2015-01-01

    Objective:To observe the VAS and JOA scores for symptoms of patients with lumbar disc hernia-tion after treating with modified FuYuan TongQi powder. Methods: Totally 84 patients of lumbar disc herniation were randomized into treatment group and control group with 42 cases in each. The cases of treatment group were administered modified FuYuan TongQi powder while those of control group given delayed release capsules di-clofenac sodium. The VAS and JOA scores and therapentic effect of patients in both groups after and before treat-ment were recorded. Results:In treatment group, the cases of clinical control were 29, marked effectiveness 6, effec-tiveness 5 and no effectiveness 2, the total effective rate of treatment was 95.24%;while in control group, those of clinical control were 26, marked effectiveness 8, effectiveness 5 and no effectiveness 3, the total effective rate of treatment was 85.71%, and differences of therapeutic effect in treatment group were significantly better than that in control group;the differences of VAS and JOA scores between two groups had no statistical meaning (P>0.05) be-fore treatment, while after treatment those differences are significant (P<0.01). Conclusion:The modified FuYuan TongQi powder can effectively improve the signs of lumbar disc herniation, relieve lumbago and limbs pain.%目的:观察加味复元通气散治疗腰椎间盘突出症VAS评分及JOA评分变化。方法:将腰椎间盘突出症患者84例随机分为2组,治疗组42例口服加味复元通气散,对照组42例口服双氯芬酸钠缓释胶囊。2组均在用药前后观察患者VAS、JOA评分及临床疗效。结果:治疗组临床控制29例,显效6例,有效5例,无效2例,总有效率95.24%;对照组临床控制26例,有效8例,显效5例,无效3例,总有效率85.71%,治疗组临床疗效优于对照组;2组治疗前VAS及JOA评分比较差异无统计学意义(P>0.05),治疗后VAS及JOA评分比

  1. 补脾益气方药对哮喘大鼠嗜酸性粒细胞趋化因子表达的影响%Effect of traditional Chinese medicine prescription for Reinfocing Pi Qi on the expression of eotaxin in asthmatic rat model

    Institute of Scientific and Technical Information of China (English)

    许珂玉; 王艳杰; 赵丹玉; 柳春

    2012-01-01

    Objective To observe the intervention influence of traditional Chinese medicine (TCM) prescription for Reinfocing Pi Qi on the expression of eotaxin in asthmatic rat, and to explore its possible mechanism. Methods SPF male SD rats were randomly divided into normal control group (A group) . Asthmatic group (B group), normal saline group (C group) , therapeutic group of Dexamethasone (D group), therapaeutic group of TCM prescription for Reinforcing Pi Oi (E group). The asthmatic models were established by the classic way of OVA sensilization and excitation. Dexamethasone and normal saline were used as positive and negative control medicine. TCM prescription for Reinforcing Pi Qi were taken once a day in 1 mL/100 g for 14 days after seting up model in the rats of E group. The number of total cells, percentages of eo-sinophil (EOS), lymphocyte, neutrophil in bronchoaleolar lavage ( BALF) fluid were calculated. Pathological change of lung tissue were observed. The expression of eotaxin on level of mRNA and protein in lung tissue were detected by RT-PCR and Western blot assay. Results EOS number of BALF and expression of eotaxin in B group and C group were higher than those in A group (P 0.05). Conclusion TCM prescription for Reinforcing Pi Qi can decrease the level of eotaxin in asthmatic rats, and alleviate inflammatory cells infiltration in lung, then inhibit airway inflamation.%目的 观察补脾益气方药对哮喘大鼠肺组织嗜酸性粒细胞趋化因子(eotaxin)表达的干预作用.方法 SPF级雄性SD大鼠随机分为对照组(A组)、哮喘组(B组)、生理盐水治疗组(C组)、地塞米松组(D组)和补脾益气方药治疗组(E组).哮喘组通过卵蛋白(OVA)致敏、激发建立大鼠哮喘模型,以生理盐水和地塞米松分别做对照治疗.E组大鼠在复制哮喘模型后,按照1 mL/100 g体质量给予补脾方药1次/d,共14 d.计数肺泡灌洗液细胞总数、嗜酸性粒细胞(EOS)、巨噬细胞、淋巴细胞和中性粒细

  2. 人参归脾汤对气血亏虚型老年颤证患者情绪障碍和疲劳感的影响%Effect of Renshen Guipi Decoction on Emotional Disorder Caused by Parkinson Disease in the Aged with Syndrome of Qi and Blood Deficiency

    Institute of Scientific and Technical Information of China (English)

    呙登俊; 王浩; 胡智伟; 江霞

    2013-01-01

    目的:探讨人参归脾汤能否改善气血亏虚型老年颤证患者的焦虑、抑郁和疲劳感,并提高生活质量.方法:109例气血亏虚型老年颤证患者,随机分为治疗组和对照组,对照组给予美多巴治疗,治疗组给予美多巴加人参归脾汤治疗,疗程均为1个月.参照《中医老年颤证诊断和疗效评定标准》进行中医疗效评定.并在治疗前后分别采用Hamilton焦虑量表(HAMA)、Hamilton抑郁量表(HAMD)、39项帕金森病问卷(PDQ39)和帕金森病疲劳量表(PFS)对两组患者进行评分.结果:治疗1个月后,治疗组中医疗效评定总有效率为60%,高于对照组的37.04% (P <0.05).治疗组HAMA、HAMD、PDQ39和PFS评分均低于治疗前及对照组(P <0.001).结论:人参归脾汤能改善气血亏虚型老年颤证患者的焦虑、抑郁和疲劳感,提高患者生活质量.%Objective: To evaluate the effect of Renshen Guipi decoction on emotional disorder caused by Parkinson disease in patients with syndrome of qi and blood deficiency in TCM. Methods: A total of 109 Parkinson patients with syndrome of qi and blood dificiency were divided into the treatment group and control group. The control group was treated with medopa tablets. The treatment group received Renshen Guipi decoction in addition to medopa. The therapy course was one month. Hamilton Anxiety Scale, Hamilton Depression Scale, the 39 - item Parkinsons disease questionnaire and PD Fatigue Scale were used to evaluate the status of the patients before and after treatment, as well as referring to Standards of Diagnosis and Evaluation of the Elderly's Tremor Symptoms of TCM. Results:After 1 -month treatment, the total response rate was 60% in the treatment group, significantly higher than that of the control group (37. 04% , P <0. 05) . The treatment group had lower scores in PDQ39, HAMA, HAMD and PFS, compared with those before the treatment and those in the control group (P <0. 001). Conclusion: Renshen Guipi

  3. 益气养阴方减轻肺癌放射治疗毒副反应疗效观察%Clinical effects of supplementing Qi and nourishing Yin fomula on reducing the side-effects of radiotherapy in lung cancer patients

    Institute of Scientific and Technical Information of China (English)

    屠洪斌

    2013-01-01

    目的 观察益气养阴方对肺癌放射治疗的减毒作用.方法 将60例肺癌患者随机分为治疗组及对照组各30例,两组患者均进行常规分割放疗,治疗组在放疗第1天开始服用益气养阴方,对照组服用利可君片,2周后对其口干、咽痛、低热等症状及外周血液毒性和一般生活状况进行综合评价.结果 两组患者的口干、咽痛、低热等症状及总分值比较差异有统计学意义(P<0.05).外周血中WBC、RBC、Hb和PLT治疗前后比较均无明显的下降,两组间差异无统计学意义(P>0.05).Karnofsky评分的显效率,益气养阴方组为78.3%,明显高于西药对照组的40.0%(P<0.05).结论 益气养阴方能明显改善肺癌患者的口干、咽痛、低热等症状,提高患者的一般生活状况,对肺癌放疗具有很好的减毒作用,值得在临床推广应用.%Objective To study the effects of Qi-supplementing and Yin-nourishing formula on reducing the side effects of radiotherapy in lung cancer patients.Methods 60 patients were randomly divided into 2 groups:30 patients in treatment group treated with Qi-supplementing and Yin-nourishing formula and 30 patients in control group treated with Leucogen tablets.Both groups were also treated with the conventional fraction radiotherapy.Patients took the drugs from the first day of radiotherapy and after 2 weeks they were evaluated comprehensively on their peripheral hematological toxicity,the scores of Karnofsky performance status and their symptoms,such as thirsty,throat sore,low fever,etc.Results There were significant differences of symptom scores including thirsty,sore throat,low fever between 2 groups (P<0.05).There were no significant differences of the counts of white blood cell,red blood cell,hemoglobin and platelet in peripheral blood before and after treatment and between 2 groups (P<0.05).The effective ratio of Karnofsky performance status in treatment group was 78.26%,which was obviously

  4. Clinical Observation on TP Chemotherapy Combined with ShenQi FuZheng Injection in Treating Advanced Ovarian Cancer%TP 化疗方案联合参芪扶正注射液治疗晚期卵巢癌的临床观察

    Institute of Scientific and Technical Information of China (English)

    狄晓鸿; 吕瑞

    2015-01-01

    目的:观察紫杉醇类+铂类(TP)化疗方案联合参芪扶正注射液治疗晚期卵巢癌患者的临床疗效、不良反应。方法:将111例晚期卵巢癌患者随机分为治疗组(57例)和对照组(54例)。对照组单用 TP 方案化疗,治疗组在此基础上加用参芪扶正注射液。观察2组临床疗效、化不良反应及治疗前后患者生活质量的变化情况。结果:2组治疗后 KPS 评分改善情况比较差异具有统计学意义(P<0.05)。治疗组在改善患者神疲乏力、纳差、恶心呕吐、失眠等方面优于对照组,差异具有统计学意义(P<0.05)。治疗组骨髓抑制、恶心呕吐、肝脏损害、肾脏损害、心脏毒性等不良反应发生率低于对照组,2组比较差异具有统计学意义(P<0.05)。总有效率治疗组为87.82%,对照组为57.41%,2组比较差异具有统计学意义(P<0.05)。复发率治疗组为12.28%,对照组为29.63%,2组比较差异有统计学意义(P<0.05)。1年生存率对照组为19.30%;治疗组为25.93%,治疗组略高于对照组,但差异无统计学意义(P>0.05)。结论:TP 化疗方案联合参芪扶正注射液治疗晚期卵巢癌疗效确切,可降低化疗的毒副反应,改善临床症状。%Objective: To observe clinical effects and adverse drug reaction (ADR) of TP chemotherapy and ShenQi FuZheng injection in the treatment for advanced ovarian cancer. Methods: All 120 patients were randomized into the treatment group and the control group, 60 cases each group, the control group accepted TP chemotherapy;while the treatment group ShenQi FuZheng injection on the foundation of TP chemotherapy. Clinical effects, adverse reaction of the chemotherapy and life quality before and after treating were observed in both groups. Results: There was significant difference in the improvements of KPS scores after treating between both groups (P0.05). Conclusion: TP chemotherapy and ShenQi Fu

  5. 补肾益气中药辅助用于缓解期肺源性心脏病的疗效研究%Effect of Chinese Medicine of Tonifying Kidney and Qi on Relieving Pulmonary Heart Disease in the Remission Stage

    Institute of Scientific and Technical Information of China (English)

    侯立强; 马端鑫; 张良; 陈静

    2015-01-01

    Objective:To explore the effect of Chinese medicine of tonifying kidney and Qi in the treatment of pulmonary heart disease in the remission stage.Methods:75 cases with pulmonary heart disease in the remis-sion stage in our hospital from September 2013 to September 2014 were selected,and were divided into a con-trol group (37 cases) and an observation group (38 cases) ,and were given conventional therapy and routine therapy combined with traditional Chinese medicine of tonifying kidney and Qi.The St George's respiratory dis-ease questionnaire ( SGRQ) score and treatment effect and brain natriuretic peptide ( BNP) concentration and heart three-dimensional color Doppler detection results in two groups were observed.Results:The total effec-tive rate in the observation group was significantly higher than that in the control group,and in the observation group after treatment the SGRQ score and the concentration of BNP and the heart of three dimensional color Doppler detection results were significantly better than those in the control group,and the difference was statis-tically significant (P<0.05).Conclusion:On the basis of routine western medicine Chinese medicine of toni-fying kidney and Qi for patients with pulmonary heart disease in the remission stage can obtain a good clinical effect.%目的:探讨补肾益气中药辅助治疗缓解期肺源性心脏病的临床效果。方法:符合纳入标准的缓解期肺源性心脏病患者75例随机分为对照组(37例)和观察组(38例),分别给予常规治疗和常规治疗联合补肾益气中药治疗。观察两组的圣乔治呼吸疾病问卷( SGRQ)评分和治疗效果以及脑纳肽( BNP)浓度和心脏三维彩超检测结果。结果:观察组治疗总有效率显著高于对照组,观察组治疗后的SGRQ评分和BNP浓度以及心脏三维彩超检测结果均显著优于对照组,差异均有统计学意义( P均<0.05)。结论:在常规西药治疗的基础上联

  6. Effect of Electroacupuncture of Acupoint Ganshu and Qimen on Behavior Changes in Rats with Stagnation of Liver-qi%电针肝俞、期门对肝气郁结模型大鼠行为学的影响

    Institute of Scientific and Technical Information of China (English)

    赵海滨; 刘子旺; 张秀静

    2012-01-01

    [目的]探讨电针肝俞、期门穴对肝气郁结模型大鼠行为学的影响.[方法]将30只Wistar大鼠随机分为正常组、模型组、电针组(电针肝俞、期门穴),采用慢性不可预知温和应激结合孤养方法复制肝气郁结证大鼠模型,分别于实验前后进行开野实验( Open-Field Test)、蔗糖水偏嗜实验,同时于实验前1d及实验第4、8、12、16、20、24、28天测量各组大鼠体质量及24h摄食量.[结果]实验14 d后,模型组大鼠体质量增加缓慢,摄食量下降,与正常组比较差异有统计学意义(P<0.05或P<0.01),实验20d后,电针组大鼠体质量、摄食量显著高于模型组(P<0.05).在实验28 d发现,与正常组比较,模型组Open-Field Test水平运动得分和垂直运动得分、蔗糖水绝对消耗及偏嗜度均显著减少,电针组上述指标水平升高,与模型组比较差异均有统计学意义(P<0.05或P<0.01).[结论]电针肝俞、期门穴对肝气郁结大鼠行为学改变具有一定防治作用.%Objective To investigate the effect of electroacupuncture (EA) on behavior changes in rats with liver-qi stagnation syndrome. Methods Thirty Wistar rats were equally randomized into normal group, model group, and EA group ( EA on acupoints of Ganshu and Qimen). Rat models with liver-qi stagnation syndrome were established by chronic unpredicted mild stress and solitary feeding. Open-Field Test and sucrose water addiction test were carried out before and after experiment. Body weight and 24-hour food intake volume were measured one day before experiment, and 4, 8, 12, 16, 20, 24, and 28 days after experiment. Results After experiment for 14 days, the body weight was increased slowly, and 24-hour food intake volume was decreased in the model group (P < 0. 05 or P <0. 01 compared with those in the normal group). After experiment for 20 days, the body weight and 24-hour food intake volume were increased in EA group ( P < 0. 05 compared with those in the

  7. Clinical Observation of Self-made Yi Qi Huoxue Qingshen Decoction on Treatment of Diabetic Dyslipidemia%益气活血轻身汤治疗2型糖尿病脂代谢紊乱临床观察

    Institute of Scientific and Technical Information of China (English)

    赵方宏

    2012-01-01

    目的:观察益气活血轻身汤对2型糖尿病脂代谢紊乱患者中医临床疗效及体重、BMI 、空腹血糖、餐后2小时血糖、HbA1c 及血脂指标的影响.方法:将60 例患者随机分为治疗组与对照组,均予糖尿病饮食、运动及西药降血糖治疗,对照组加服辛伐他汀,治疗组加服益气活血轻身汤;两组疗程均为60d.比较两组中医临床疗效及体重、BMI 、空腹血糖、餐后2小时血糖、HbA1c 及血脂指标的变化.结果:治疗组总有效率高于对照组(P<0.05),其空腹血糖、餐后2小时血糖、HbA1c 及血脂指标改善亦优于对照组(P<0.01).结论:益气活血轻身汤能明显改善2型糖尿病脂代谢紊乱患者中医临床症状及体重、BMI 、空腹血糖、餐后2小时血糖、HbA1c 及血脂代谢.%Objective: To study the therapeutic effect of Yi Qi Huoxue Qingshen decoction to Diabetes with dyslipidemia ,and its effect to weight,BMI(Body Mass Index),FBG(Fasting plasma glucose),P2HBG(Postprandial 2 hour glucose), HbAlc and blood fat. Methods:60 patients diagnosed of Diabetes with dyslipidemia were randomly divided into controlgroup and treatmentgroup (30 patients each). On the basis of conventional therapy in Westernmedicine, in eluding Diabetes Exercise and diet Therapy,Anti-diabetic drugs,use simvastatin on the concrogroup,while the patients in treatmentgroup had the added self-made Yi Qi Huoxue Qingshen decoction -1 devided into 2 times each day for everyone and for 60d. All the patients in two groupswere treated one course of treatment (60d), and the therapeutic effect before and after treatment and related detection indicator in biochemistrywere compared,as desbribed above.Results:The totaleffective rate in treatmentgroup is higher than that in controlgroup (P<0.05); and FBG,P2HBG, HbAlc and blood fat improve also better than the control group (P<0. 01). Conclusion:Yi Qi Huoxue Qingshen decoction can significantly improve the type 2 diabetic lipid

  8. Systematic Review of the Effectiveness and Safety of HuangQi Injection in Treating Diabetic Nephropathy%黄芪注射液治疗糖尿病肾病有效性及安全性的系统评价

    Institute of Scientific and Technical Information of China (English)

    任芳; 徐厚谦

    2014-01-01

    Objective: To assess the effectiveness and safety of HuangQi injection in treating diabetic nephropathy (DN) systematically. Methods: The papers about randomized or semi-randomized controlled trials (RCT) of HuangQi injection in treating DN were collected and searched in Cochrane library clinical controlled trials database, MEDLINE, EMBASE, CNKI, CBM, WangFang database, as well as related conference papers, dissertations and the reference in the obtained literature. Two investigators chose the trials and drew the informations indenpedently, the quality of the included studies was evaluated with modified Jadad rating scale, Meta analysis was performed with software Rev Man 4.2.2. Results:Altogether 16 RCTs were included and there were 1058 patients. Most of trial methodologies were of lower quality and with small sample size.“Funnel plots” were not equally distributed, which suggested that publication bias might be existed (it showed that trial with negative results might not be published) and the qualities of trial methodologies were lower. The results of Meta analysis showed:①compared with blank control group, HuangQi injection could reduce 24 hours urinary protein, blood urea nitrogen (BUN) and glycerin trilaurate (TG) of DN patients, and improve total effective rates of body signs and symptom of DN patients; ②compared with blank control group,HuangQi injection could decrease 24 hours urine albumin excretion rate (UAER), 24 hours urinary protein, serum creatinine(Scr), BUN, TG and total cholesterol(TC) of DN patients at early stage,but it couldn’t lower Scr and TC of DN patients at clinical stage and advanced stage;③HuangQi injection presented similar effects to captopril in decreasing 24 hours UAER, Scr and BUN of DN patients at early stage;it also was similar to sodium ozagrel injection in lowering 24 hours UAER and BUN of DN patients at early stage, but it showed less effects in decreasing Scr of DN patients at early stage as sodium ozagrel

  9. 牵引体位变化对气滞血瘀型腰椎间盘突出症患者临床疗效的影响%The Effect of Traction Position Change on Clinical Efficacy in Patients with Lumbar Disc Herniation of Qi stagnancy and Blood Stasis Type

    Institute of Scientific and Technical Information of China (English)

    佟德民; 孙凤杰; 孙利群

    2016-01-01

    目的:探讨不同牵引体位对气滞血瘀型腰椎间盘突出症患者短期临床疗效的影响。方法将120例符合纳入标准的气滞血瘀型腰椎间盘突出症患者随机分为治疗组和对照组,每组60例。两组均口服龙血竭片,4粒/次,每日3次,连续服用14 d,治疗组采取 Flower 位腰椎牵引,对照组采取传统仰卧位牵引,每次牵引20 min,连续牵引14 d。观察两组患者治疗前后视觉模拟疼痛评分(VAS)、日本骨科协会(JOA)腰椎功能评分及中医疗效。结果两组患者治疗后 VAS、JOA 评分较治疗前均明显降低,差异均有统计学意义( P 0.05)。结论牵引前腰痛缓解体位是决定腰椎间盘突出症患者牵引治疗体位和临床疗效的重要因素。%Objective To explore the effect of different traction positon on short clinical efficacy in patients with lumbar disc herniation of qi stagnancy and blood stasis type. Methods 120 Patients with qi stagnancy and blood stasis type of lumbar disc herniation were randomly divided into two groups,respectively 60 per group. All had been taken Long Xuejie Tablet,four tablets per time,three times per day for fourteen days. Flower position traction had been used for treatment group and traditional traction for control group to observe VAS、JOA scores and Chinese medicine efficacy changes after treatment. Results VAS and JOA scores in two groups obviously significantly reduced and there were significant differences in VAS and JOA scores of two groups after treatment. The effective rate of treatment group was percent 96. 67 and control group was percent 83. 33. Conclusion The positon to alleviate lumbago before traction is an important factor to de-termine traction position and efficacy.

  10. Clinical Research of Shengmai Yin in Treating Pulmonary Tuberculosis with Hyperhidrosis of Type of Deficiency of Both QI and YIN%生脉饮治疗气阴两虚型肺结核并多汗症临床研究

    Institute of Scientific and Technical Information of China (English)

    石广灿

    2014-01-01

    Objective:To observe the clinical efficacy of Shengmai Yin in treating pulmonary tuberculosis with hyperhidrosis of type of deficiency of both QI and YIN. Methods:40 cases of pulmonary tuberculosis patients were randomly divided into treatment group and treatment group,20 cases in each group. The treatment group was given routine anti-tuberculosis treatment combined with Shengmai Yin,10 mL each time,three times a day. The control group was given routine anti-tuberculosis treatment combined with Oryzanol,30 mg each time,3 times a day. 30 days as a period of treatment,then observe the curative effect after 1 course. Results:Compared the clinical curative effect of two groups,the cure rate was 60. 0% in treatment group and 30. 0% in control group. Compared the cure rate of two groups,the difference was statistically significant(P0. 05). Conclusion:Shengmai Yin in treating pulmonary tuberculosis with hyperhidrosis of type of deficiency of both QI and YIN has better clinical curative effect.%目的:观察生脉饮治疗气阴两虚型肺结核并多汗症的临床疗效。方法:40例肺结核患者随机平均分为两组。治疗组20例,在常规抗结核治疗基础上给予生脉饮口服液,每次10 mL,每日3次,口服。对照组20例,在常规抗结核治疗基础上给予谷维素,每次30 mg,每日3次,口服。30 d为1个疗程,1个疗程后统计疗效。结果:两组临床疗效比较:治疗组治愈率为60.0%,对照组治愈率为30.0%,两组比较,差异有统计学意义( P0.05)。结论:生脉饮治疗气阴两虚型肺结核并多汗症临床疗效较好。

  11. 从“革命排满”到“大、小民族主义”——试论梁启超近代民族主义的形成%From "Revolution and Exclude Manchuria" to "Large and Small Nationalism"——Comment on the Formation of LIANG Qi-chao's Modern Nationalism

    Institute of Scientific and Technical Information of China (English)

    张文涛

    2011-01-01

    1903年梁启超"大、小民族主义"概念的提出是近代中国民族主义形成的标志。从东渡日本之初不时声言"革命排满"到游历美洲后提出"大、小民族主义",梁启超这一近代民族主义的形成过程伴随着中国传统"夷夏之辨"、"天下观"等思想与西方近代民族主义的对接与调适。其中,梁氏本人对瑞士政治学家伯伦知理国家主义思想的借鉴至关重要,它促使中国传统主要以文化取向为主的"夷夏之辨"、"天下"思想最终转化为以国家取向为特征的"大、小民族主义",进而衍化出了"中华民族"的概念。%In 1903,LIANG Qi-chao put forward "large and small nationalism",it is a symbol of Chinese modern nationalism.Form sometimes advocate "revolution and exclude Manchuria" in Japan early to maintain "large and small nationalism" in American,along with Chinese traditional "Yi Xia Distinction" dock and adjust to modern Western nationalism.LIANG Qi-chao draw lessons from Bluntchl's National ideology is essential,it is promote Chinese traditional "Yi Xia Distinction" "world" ideology ultimately into the "large and small nationalism",and then derived the concept of "Chinese nation".

  12. 高丽后期“海左七贤”宗宋诗风论析%The Analysis of a Style of the Song Poetry of HaiZuoQiXian in the Second Half of KoryǒDynasty

    Institute of Scientific and Technical Information of China (English)

    杨会敏

    2014-01-01

    高丽后期的“海左七贤”不仅从理论上明确倡导宋诗,在创作上也有宗宋倾向。其汉诗的主题意蕴深受宋诗人影响:伤时悯乱的政治诗体现了忧国忧民的宋诗情韵;咏怀诗蕴含了源于宋诗经世致用的思想内核;写景、咏物诗具有宋诗的尚意倾向。另外,其诗歌的题材内容还具有生活化、谐谑化的宗宋倾向,在艺术风格、技巧上,体现了重学问、擅用典,重个性、求创新的宋诗因子。“海左七贤”对宋诗着力创新、自成一家的创作精神的继承是其与宋诗本质上的最契合之处。%HaiZuoQiXian in the second half of KoryǒDynasty not only theoretically and Clearly advocates Song poems but it has the tendency of learning from Song poems in their Chinese Poetry creation.The theme and connotation of their Chinese Poetry is deeply influenced by song poets,the Political Poem of grieving over time and showing sympathy for war demonstrates their concern about his country and his people which is similar to Song poems,the core ideology of poem of expressing is knowledge is useful to the country,the poem of describing the scenery and singing of goods has a tendency of admiring meaning similar to Song poems,in addition,its subj ect matter is closely connected with people’s daily life and pleasantry similar to Song poems.In artistic style and skills,it embodies attaching importance to knowledge and individual character,using allusions and striving for breakthrough.HaiZuoQiXian’s the succession of creative spirit of striving for breakthrough and being unique in their own style most agree with Song poems in nature.

  13. Discussion on the Treatment of Children with Asthma in Remission Stage from Healthy Qi Deficiency and Pathogenic Factor Excess%从正虚邪实探讨中医药对小儿哮喘缓解期的治疗

    Institute of Scientific and Technical Information of China (English)

    邢琼琼; 赵霞

    2016-01-01

    Objective] The treatment of pediatric asthma in remission period is summarized from the positive and negative aspects, in order to provide new ideas and methods for clinical treatment. [Methods] By consulting the related literatures on the traditional Chinese medicine treatment of children with asthma in remission phase, the paper mainly summarized the different physicians' understanding of pathogenesis and approaches to the treatment of pediatric asthma in remission stage. [Results]The treatment of physicians for pediatric asthma in remission phase can be divided into asthenia healthy qi and sthenia pathogenic factor syndrome.The treatment of healthy qi deficiency mainly includes treating lung,spleen,kidney seperately;curing lung-spleen,lung- kidney, spleen-kidney ;treating three viscera meanwhile.The therapy of pathogenic excess contains treating wind,phlegm,stasis respectively;curing phlegm-stasis. [Conclusion]The treatment of traditional Chinese medicine for pediatric asthma has a unique advantage in improving children's physique, reducing the frequency of asthma attacks, and improve children's life quality which has significant clinical effect.%[目的]从正虚和邪实两方面对小儿哮喘缓解期的治疗方法进行总结,以期能为临床治疗提供新的思路与方法。[方法]将近年关于中医药治疗小儿哮喘缓解期的文献进行检索,整理、归纳各医家对小儿哮喘缓解期的病机认识和治疗方法。[结果]各医家对小儿哮喘缓解期的治疗从正虚和邪实两方面论治,从正虚治疗主要包括单独从肺、从脾、从肾论治,从肺脾、肺肾、脾肾治疗以及从肺脾肾三脏综合论治;而从邪实治疗则包括单独从风、从痰、从瘀论治以及痰瘀综合治疗。[结论]中医药对小儿哮喘缓解期的治疗有着独特的优势即在改善患儿体质、减少哮喘发作次数、以及提高患儿生存质量等方面临床疗效显著。

  14. Establishment of syndrome of stagnation of liver Qi model in rats and primary study on related hormones of hypothalamus-pituitary-adrenal axis%肝气郁结证动物模型的建立及HPA轴相关激素的初步研究

    Institute of Scientific and Technical Information of China (English)

    赵海滨; 刘子旺; 张秀静

    2011-01-01

    [目的]建立并验证“肝气郁结证”大鼠模型,在此基础上研究“肝气郁结证”下丘脑-垂体-肾上腺(HPA)轴相关激素的改变.[方法]20只Wistar大鼠随机分为对照组、模型组.采用慢性应激+孤养方法制备“肝气郁结证”大鼠模型,通过行为学观察、蔗糖水偏嗜实验、开野实验评价模型.运用酶联免疫吸附试验( ELISA)技术对两组大鼠血清进行HPA轴相关激素分析.[结果]肝气郁结模型大鼠表现为躲避、活动减少、大便松散、皮色失去光泽,造模第2周开始生长较对照组缓慢,摄食量减少(P<0.05);28 d造模后,水平得分、垂直得分较正常组均明显降低(P<0.01,P<0.05),血清皮质酮(CORT)、促肾上腺皮质激素释放激素(CRH)的含量明显升高(P<0.01).[结论]从病因学、行为学和症状表现上成功构建了肝郁证大鼠模型,并进一步证实模型大鼠呈HPA轴亢进状态,有助于阐释肝郁证病理改变的本质.%[Objective] To establish and validate the syndrome of stagnation of liver Qi model in rats. The change of hormones related to hypothalamus-pituitary-adrenal (HPA) axis was investigated. [Methods] Twenty rats were randomly divided into two groups: control group and model group. We adopted the method of chronic stress combining with isolated breeding to prepare the model in rats with the stagnation of liver-Qi syndrome. Open-Field test and partial addicted to sugar water test were carried out one the day before experiments and after experiments. The rat's body weight and food intake in 24 h were recorded on the day before experiments, and on the 4th , 8th, 12th, 16th, 20th, 24th and 28th day during experiments respectively. The content of adrenocorticotropic hormone-releasing hormone (CRH) and serum corticosterone (CORT) were measured by ELISA method. [Results] There were some appearance of abnormal behaviors, such as decrease of elusion, slackness, looser stools, and matte fur among model

  15. Manifestations of Healthy Qi-strengthening and Pathogen-eliminating Function of YinQiao Powder in Treating Infectious Diseases of Pediatrics Department%“扶正祛邪”在银翘散治疗儿科感染性疾病中的运用

    Institute of Scientific and Technical Information of China (English)

    王继芳; 史正刚

    2015-01-01

    YinQiao power can have such healthy Qi-strengthening functions as enhancing the adjustment of the central nerve, the improvement of cell and humor immunity and the excretion of sweat gland and have the pathogen-eliminating advantages of dilating the peripheral capillary to eliminate pathogens and fight against bacteria, virus and the allergy, so that the modified prescriptions can be widely used to treat infant infectious diseases, such as upper respiratory tract infection, influenza, pneumonia, herpes, epidemic parotiditis, to name list.%银翘散具有加强中枢神经调控、增强细胞及体液免疫、促进汗腺分泌等独特的“扶正”作用和扩张周围毛细血管以透邪及抗菌、抗病毒、抗过敏等“祛邪”优势,加减变化可广泛应用于小儿感染性疾病。

  16. 家国史诗 人生悲歌——评齐邦媛文学回忆录《巨流河》%Epic of Home and Country and Tragedies of Life: On Qi Bangyuan's Juliu River

    Institute of Scientific and Technical Information of China (English)

    廖斌

    2011-01-01

    介绍了台湾著名作家齐邦媛的回忆录《巨流河》,认为其是恢弘的家国史诗与沧桑的人生悲歌。指出,《巨流河》写尽了中华民族饱受异族凌辱、战乱与分离之苦;写尽了家的颠沛流离与生离死别;写尽了人世沧桑与人生感怀。%Juliu River, the memoirs of famous Taiwanese writer Qi Bangyuan, is described, which is considered a grand epic of home and country and elegy of the vicissitudes of life. In this book, the author wrote the Chinese nation suffered from alien abuse, war and the pain of separation; wrote the homeless and miserable of people and separation between loved ones in life or death; and wrote the vicissitudes and recollections of life.

  17. Effect of supplementing qi, blood- activating and kidney- nourishing therapy on postoperative recovery in patients with lumber disc herniation%益气活血补肾法对腰椎间盘突出症术后恢复的影响

    Institute of Scientific and Technical Information of China (English)

    郑少伟; Shaikh Atik Badshah; 王健; 蒋晖; 李敏; 陈国奋

    2015-01-01

    Objective To investigate the effect of supplementing qi, activating blood circulation and tonifying kidney therapy on the postoperative outcomes of patients undergoing lumber intervertebral disc herniation. Methods From January 2010 to May 2012, 120 patients with lumbar intervertebral disc herniation undergoing surgical treatment in Nanfang hospital were randomized into two equal groups to receive routine therapy (control group) and additional treatment with Yiqi Houxue Bushen Decoction (treatment group). The effect of the interventions was evaluated by assessing the Visual Analogue Scale (VAS), Japanese Orthopedic Association Scores (JOA), WHO Quality of Life-BREF (WHOQOL-BREF), length of hospital stay and adverse event. Results All the 120 patients were followed up and analyzed. Significant differences were found between the treatment and control groups in VAS, JOA Scores, and WHOQOL-BREF (P0.01)。但在JOA评分方面,观察组要优于对照组,差异有统计学意义(P<0.01)。结论益气活血补肾法对腰椎间盘突出症患者术后恢复,改善术后主要症状体征及减少不良事件方面存在优势。

  18. On the Acceptance of Chinese Literature in Nihon Ryolkl---Based on an Interpretation of the Confucian Allusion “Meng Chang Qi Shan”%《日本灵异记》对中国文学的接受研究--以儒学典故“孟尝七善”考释为例

    Institute of Scientific and Technical Information of China (English)

    刘九令

    2014-01-01

    As the first collection of Buddhism stories in its literature history of Japan,NihonRy-oiki not only absorbs some elements of Buddhist literature but also cites some Confucius allusions of China.Some Confucius allusions are altered into Buddhist stories by using “Bi Fu”to spread Buddhism doctrines.By taking the Confucian allusion “Meng Chang Qi Shan”and the significance of choosing this allusion as examples,this paper mainly attempts to do some research on the ac-ceptance of Chinese literature in NihonRyoiki.%日本文学史上第一部佛教说话集《日本灵异记》在编撰的过程中,不仅袭取了中国佛教文学,而且对中国的儒学典故也加以了利用,并通过比附的手法,将儒学典故这一文学元素改造成为佛教的内容,为宣扬佛教教义服务。文章以“孟尝七善”这一典故的出典及其使用意义为考察对象,揭示《日本灵异记》对中国文学的接受情况。

  19. Therapy with "Replenishing Qi, Nourishing Yin and Dredging Collaterals" Prevents the Progression of Diabetic Nephropathy by Up-regulating SIRT1%"益气养阴通络法"通过调控SIRT1延缓糖尿病肾病进展的研究

    Institute of Scientific and Technical Information of China (English)

    刘伟敬; 梁碧婵; 胡海滢; 刘玉宁; 陈秋华; 王永恒; 郑媛媛; 刘华锋

    2013-01-01

    目的:观察SIRT1在"益气养阴通络法"治疗糖尿病肾病(diabetic nephropathy,DN)中的作用.方法:将179例确诊为Ⅲ期和Ⅳ期DN患者随机分为基础治疗对照组(76例)和"益气养阴通络法"综合治疗组(103例),评价两组患者临床症状疗效、尿微量白蛋白 (Alb)及肌酐清除率(Ccr);并通过免疫组化和免疫荧光法分析SIRT1在人肾组织中的表达情况及在DN患者中的变化情况;进一步通过逆转录病毒沉默原代大鼠肾小管上皮细胞(TEC) SIRT1后,观察TEC在AGE-BAS刺激后的凋亡情况.结果:经过6个月治疗,"益气养阴通络法"综合治疗组中医症状积分改善、微量白蛋白排泄率降低及肌酐清除率升高的患者比率明显高于基础治疗对照组(P<0.01);停药6个月后进行随访,"益气养阴通络法"综合治疗组的远期疗效也优于基础治疗对照组(P<0.01).免疫组化和免疫荧光显示,SIRT1在人肾组织的足细胞、内皮细胞及小管上皮细胞等均有表达,并且上述表达在DN患者中明显降低;而经"益气养阴通络法"治疗后SIRT1表达明显增强.进一步通过体外实验证实,沉默SIRT1后,cleaved caspase3蛋白表达在AGE-BSA刺激的TEC中明显升高.结论:"益气养阴通络法"在治疗DN过程中有着显著作用,而上述疗效可能是通过上调肾脏固有细胞中SIRT1实现的.%Objective:To observe the effect of SIRT1 during the treatment of on the therapy for diabetic nephropathy( DN ) through Replenishing qi, nourishing yin and dredging collaterals . Methods: 179 Ⅲ and Ⅳ DN patients were randomly divided into control group with basic treatment ( 76 cases ) and investigation group with the combination of basic treatment and " replenishing qi, nourishing yin and dredging collaterals" therapy ( 103 cases ). Clinical symptoms, albumin excretion and creatinine clearance rate were evaluated. The expression of SIRT1 in human renal tissue and the change of SIRT1 expression in DN patients

  20. View of Sima Qian' s Profound Criticism of Dark Feudal Regime Tyranny from Biography of Marquis Wei Qi and Wu An in Historical Records%司马迁对封建黑暗专制制度的批判——解读《史记·魏其武安侯列传》

    Institute of Scientific and Technical Information of China (English)

    周虹云

    2011-01-01

    Biography of marquis Wei Qi and Wu An in Historical Records is a famous works about dark feudal regime tyranny of the Western Han Dynasty, written by Sima Qian. This book exposed the darkness of feudal regime tyranny and the brutal essence of ruling class by Wai Wei' s despicable acts, feudal aristocracy' s power struggles, bureaucratic snobbish, inconstancy of human and so on. It expressed Sima Qian' s profound criticism of reality.%《史记·魏其武安侯列传》是揭露西汉黑暗的封建专制制度的力作,司马迁从外戚的卑劣行径,封建贵族之间的争权夺利以及当时官场的势利、世态炎凉等不同侧面,有力揭示了封建专制制度的黑暗和统治阶级残酷暴虐的本质,表达了司马迁对现实的深刻批判。

  1. Under Role Conflict's Tragedy Life --On the Cao Qi-qiao in "Golden Lock"%角色冲突下的悲剧人生——试论《金锁记》中曹七巧

    Institute of Scientific and Technical Information of China (English)

    宋小梅

    2011-01-01

    《金锁记》中的曹七巧是一个性格复杂变态的人物形象,从社会学角色理论的角度解读文本,用角色冲突理论分析曹七巧的心理,并试着证明形成这个人物的变态心理及行为的主要原因是人物所担任的社会角色及其角色冲突。%Cao Qi-qiao in "Golden Lock" is a disposition complex abnormal character image. The author interprets the text from a sociological perspective of role theory,, analyzes the role psychology of Cao Qiqiao with the role conflict theory, and tries to prove that the main reason of this character" s abnormal psychology and the behavior is the character of the social role and its role as a conflict.

  2. Clinical observation on Zhigankang Wan treating 60 cases with fatty liver of dampness retention and Qi-stagnation and blood stasis%脂肝康丸治疗湿浊凝结、气滞血瘀型脂肪肝60例临床观察

    Institute of Scientific and Technical Information of China (English)

    姜爱华

    2014-01-01

    60 cases of damp reten tion and Qi-stagnation and blood stasis were divided randomly into treatment group and control group,each 30 cases. The treatment group we re given Zhigankang Wan and the con trol group were given C ompound dichloroacetat e diisopropylamine tablets,both fo r 12 weeks , wi th clin ical efficiency of 83 .3%and 60% respectively,which show ed significant dif ferences (P<0.05).%将60例湿浊凝结、气滞血瘀型脂肪肝患者随机分为治疗组及对照组各30例,治疗组用脂肝康丸、对照组用复方二氯醋酸二异丙胺片治疗12周,治疗组临床总有效率83.3%、对照组总有效率60%,两组相比差异有统计学意义(P<0.05)。

  3. 补脾益气中药对哮喘大鼠BALF中IL-5及GM-CSF含量的影响%Effect of Prescription and Medicine of Strengthening Spleen and Benefiting Vital Qi on Content of IL-5 and GM-CSF in BALF of Asthma Rat

    Institute of Scientific and Technical Information of China (English)

    杨玲; 朱晓明; 王磊; 薛丹; 魏庆宇

    2011-01-01

    Objective: To explore the role of IL -5 and GM - CSF in the course of asthmatic incidence, and the effect of the prescription and medicine of strengthening spleen and benefiting Vital Qi on content of both of them. Methods: Twenty - four male rats were randomly divided into three groups: normal control group; model group; Chinese Herbal group. Every group has eight rats. A sensitized asthmatic rat model was obtained by intraperitoneal injection egg albumin,inactivated Bordetella pertussis vaccine and aluminum hydroxide dry flour of prepared solution,and provocation by atomization breathe in egg albumin. Normal control group was supplied with paries aequales physiological saline to substitute antigen liquid; Chinese Herbal group was given prescription and medicine of strengthening spleen and benefiting Vital Qi( Add Ingredients Jade Screen Powder. The change of content of IL - 5 and GM - CSF in broncho - alveolar lavage fluid ( BALF) were observed. Results: Compared with normal control group, Model group BALF has dramatic growth of the content of IL-5 and GM-CSF( P<0.05 in all or P<0.01) .especially the IL-5. Correlation analysis showed that GM -CSF and IL-5 were significantly direct correlated (r1 =0.519,r2 =0.521 ,P<0.05 in all). The prescription and medicine of strengthening spleen and benefiting Vital Qi can decrease the contents of IL - 5 and GM -CSF in BALF( P<0.05 or P<0.01). Conclusion:IL -5 and GM - CSF play an important role in the course of the asthmatic rat fe air way inflammatory cell infiltration. They may accelerate the emergence and development of the nonspecific airway inflammation of asthma. There exists close link between IL-5 and GM - CSF, and it is expected that this has synergistic action on the aggregation , migration, activation and adherence of the eosinophil (EOS). The prescription and medicine of strengthening spleen and benefiting Vital Qi( Add Ingredients Jade Screen Powder) can improve the airway' s inflammation state through

  4. Analysis on the Misuse and Causes of “chu qi bu yi ”in Romance of the Three Kingdoms and Other Works%《三国演义》等作品中“出其不意”的误用及其成因

    Institute of Scientific and Technical Information of China (English)

    蔡亚玲

    2015-01-01

    成语是长期以来形成的固定词组,在使用中都有其固定的用法,但近来考察语料发现《三国演义》等古代作品中成语“出其不意”却有少量与众不同的用法。这一特殊用法数量有限,且主要分布在通俗文学作品中。它的出现应与说、写者的“误用”有关,而不能将其看作是独立的义项。%The idioms are fixed phrases for a long time. It has fixed usage in using, but we find the idiom“chu qi bu yi ” which has a few different usage through the study of the corpus such as Romance of the Three Kingdoms and other ancient works recently. The quantity of special usage not only is limited, but also it distributes mainly in the popular literary works. Its appearance should be told the misuse of the writer, and it can not be regarded as independent sense.

  5. 齐鸿按动疗法治疗骶髂关节半脱位引发梨状肌疼痛经验%QI Hong’s Experience in Treating Piriformis Pain Caused by Subluxation of Sacroiliac Joint by Using Pressing Therapy

    Institute of Scientific and Technical Information of China (English)

    洪流

    2017-01-01

    本文旨在系统总结北京按摩医院齐鸿主任医师治疗骶髂关节半脱位引发梨状肌疼痛的特色手法——按动疗法。分别从“以按治痛”和“以动治动”两方面介绍了其操作手法,并从按动疗法、骶髂关节半脱位与梨状肌疼痛的相关性、骶髂关节的“微动”与“易动”等方面进行了讨论。%This article aims to conclude the pressing therapy of QI Hong, chief physician in Beijing Massage Hospital. It introduced the therapy from the two aspects of “treating pain with pressing” and “treating dislocation with moving”. It also discussed pressing therapy, the correlation of subluxation of sacroiliac joint and piriformis pain, and “micro” and “mobile” of sacroiliac joints.

  6. 基于“方证相应”理论验证慢性间歇性缺氧模型气阴两虚证候属性的初步研究%Primary study on verifying the Deficiency of both Qi and Yin Syndrome attribute of chronic intermittent hypoxia mice model based on the theory of "Syndrome Differentiation through Formula Effect Assessment"

    Institute of Scientific and Technical Information of China (English)

    王文萍; 柴程芝; 寇俊萍; 朱丹妮; 严永清; 余伯阳

    2012-01-01

    Objective: To confirm the Deficiency of both Qi and Yin Syndrome ( DQYS) attribute of the chronic intermittent hypoxia animal model; Methods; Sheng-mai-San ( SMS) , one of the typical formulae of benefiting qi and nourishing yin was chosen to observe it' s influence on the index simulating the clinical features of DQYS. Results: SMS can significantly improve the abnormal changes including body weight, food intake, locomotive activity and electrocardiogram, etc induced by chronic intermittent hypoxia, it can increase the body weight and food intake, make the locomotive activity and heart rate stable, prevent T wave elevating and prolong the bleeding time. Conclusion; The typical formula of benefiting qi and nourishing yin can improve the abnormal changes induced by chronic intermittent hypoxia, the study primarily confirmed the DQYS attribute of chronic intermittent hypoxia mice model from the point view " Syndrome Differentiation through Formula Effect Assessment".%目的:验证慢性间歇性缺氧模型的气阴两虚证候属性.方法:选择益气养阴的代表方生脉散干预模型,考察其对模拟气阴两虚证的各项指标的影响.结果:生脉散能够显著改善慢性间歇性缺氧诱导的小鼠体重,摄食量,自发活动,心电图等各项指标的异常改变,使小鼠体重及摄食量增加,自发活动和心率趋于稳定,T波随缺氧时间的延长无显著增高;断尾出血时间与模型组比较明显延长.结论:益气养阴的代表方生脉散能显著改善模拟气阴两虚证的慢性间歇性缺氧小鼠各项指标的异常改变,从“以方测证”的角度初步证实了模型的气阴两虚证候属性.

  7. 益气解毒法不同组方对鼻咽癌细胞迁徙运动潜能及细胞伪足的影响%Effects of the original and modified Qi-Boosting Toxin-Resolving Formulae on moving potentiality and cellular pseudopod of NPC cell line CNE2Z

    Institute of Scientific and Technical Information of China (English)

    尚云峰; 田道法

    2011-01-01

    目的 研究益气解毒法不同组方对鼻咽癌细胞迁徙运动潜能及其细胞伪足的影响.方法 以正常大鼠血浆为对照,分别应用益气解毒方原方及其改方大鼠药物血浆对CNE2Z细胞进行干预,采用划痕实验法评价不同组方药物对靶细胞迁徙运动潜能的影响,以扫描电镜观察细胞伪足形态特征,分析靶细胞的反应特性.结果 益气解毒原方对CNE2Z细胞的迁徙运动潜能显示抑制效应,细胞迁徙能力较差,伪足伸展不明显;益气解毒改方则对靶细胞迁徙运动潜能显示为促进效应,细胞伪足伸展长度较长.结论 同为益气解毒法的组方,由于剂量构成比不同,各方对鼻咽癌细胞迁徙运动潜能的药效学差异巨大.这样的药理效应特点,对中药复方的合理组方提出了严格要求.%Objective To investigate the effects of original and modified Qi-Boosting Toxin-Resolving Formulae (QBTRF) on moving potentiality and cellular pseudopod of nasopharyngeal carcinoma cell line CNE2Z based on an experimental study. Methods Investigated were the effects of two herbal medicinal formulae, the original and modified QBTRF, on moving potentiality and cellular pseudopod of NPC cell line CNE2Z by medicinal blood plasma assaying procedures, with healthy rat plasma as the control in a routine way. Here, scratch test was taken to determine the moving potentiality with their changes in morphologic characteristics of cells CNE2Z under light microscope, and electron microscopy was utilized to observe pseudopod features of these cells to evaluate their changes in potential motility in the response to the intervening reagents. Results It was shown that the original QBTRF brought about an inhibitory effect on the moving potentiality of CNE2Z cells showing a much shortened moving distance with looser growing status and silkiness-like pseudopod expanding not so obvious as that in controlling cells, while the modified OBTRF brought about a promoting

  8. Influence of medicinals with actions of clearing heat and tonifying qi on insulin sensitivity in KKay mice with early type 2 diabetes%清热益气中药对初发2型糖尿病KKay小鼠胰岛素敏感性的影响

    Institute of Scientific and Technical Information of China (English)

    胡照娟; 柳红芳; 张艳红; 聂波; 张冬梅; 娄丽霞; 郭会霞

    2012-01-01

    目的 观察清热益气中药干预初发2型糖尿病KKay小鼠血糖水平、胰岛素敏感指数的效果及肝脏病理形态变化,探讨中药治疗初发2型糖尿病的作用机制.方法 10周龄雄性初发2型糖尿病KKay小鼠27只按血糖值随机分为模型组、罗格列酮组[0.67g/(kg·d)]、中药组[8.3 g/(kg·d)].正常对照组选10周龄雄性C57BL/6J小鼠9只.各组连续灌胃给药4周后取材,测定其随机血糖、空腹血糖、胰岛素,肝脏切片HE染色观察组织学改变.结果 给药4周后,与正常组相比,模型组胰岛素敏感指数明显降低(P<0.01),空腹血糖、随机血糖明显升高(P<0.01),肝脏组织明显脂肪变性.中药组与模型组相比,胰岛素敏感指数高于模型组(P<0.01);空腹血糖值低于模型组(P<0.01);中药组随机血糖值较模型组有下降,但无统计学意义(P>0.05);中药组肝脏结构明显好于模型组.结论 清热益气中药可改善初发2型糖尿病KKay小鼠的胰岛素抵抗,增加胰岛素的敏感性从而改善血糖水平,并能有效保护肝脏组织形态结构.%Objective To observe the influence of medicinals with actions of clearing heat and tonifying qi on the level of plasma glucose, insulin sensitive index (ISI) and pathomorphology of liver in KKay mice with early type 2 diabetes. Methods Male KKay mice with early type 2 diabetes ( 10 weeks old, n= 27) were divided into model group, rosiglitazone group (0.67 g/kg · d) and Chinese medicinal group (8. 3 g/kg · d) according to the value of plasma glucose. Other male C57BL/6J mice ( 10 weeks old, n= 9) were selected as normal group. All groups were intragastrically given corresponding medicinals for 4 weeks and then the levels of random blood sugar (RBS) , fasting plasma glucose (FPG) and isuline were detected. The histomorphologic changes of liver were observed by using HE staining of liver section. Results Compared with normal group, ISI decreased significantly (P 0. 05 ) in

  9. Phase Ⅲ clinical trial of Yiqitongluo granule in the treatment of stroke with qi-deficiency and blood-stasis syndrome%益气通络颗粒治疗中风病(气虚血瘀证)Ⅲ期临床试验

    Institute of Scientific and Technical Information of China (English)

    张纲; 张华健; 刘军锋; 艾长山

    2012-01-01

    目的 评价益气通络颗粒治疗中风病(气虚血瘀证)的有效性和安全性.方法 随机、双盲、阳性药平行对照、多中心临床试验设计,将440例入组病例分成试验组330例,对照组110例,分别口服益气通络颗粒(每袋4 g+每袋8 g,共2袋),消栓颗粒(每袋4 g)加空白模拟剂(每袋8 g),每日3次,疗程4周.治疗结束后对患者的症状、体征以及实验室指标进行评估.结果 试验组和对照组的中医证候疗效总有效率为80.1%和68.8%,有显著性差异(P<0.05);神经功能综合疗效总有效率分别为83.4%和72.5%,有显著性差异(P<0.05).研究期间2组均无严重不良事件,无因不良事件而退出的病例.结论 益气通络颗粒治疗中风病(气虚血瘀证)用药安全,疗效确切.%Objective To evaluate the efficacy and safety of Yiqitongluo granule in the treatment of stroke with qi - deficiency and blood - stasis. Methods Four hundred and forty patients were enrolled in a randomized , double - blind, active - controlled, multicenter trial. The patients were randomized to orally receive Yiqitongluo granule 12 g(trial group, n - 330) or Xiaoshuan granule 4 g plus placebo 8 g ( control group , n = 110) each time,3 times daily for 4 weeks. The symptom score scale and the laboratory index were used to evaluate clinical efficacy and safety of the two groups. Results The total efficiency based on TCM syndrome of the trial group and control group were 80. 1% and 68. 8% (P < 0. 05) , and the total efficiency based on nervous function of the two groups were 83. 4% and 72. 5% ( P < 0. 05 ) , respectively. During the study, there was no serious adverse effect in two groups, and no one didn' t complete the clinical trial because of adverse effect. Conclusion Yiqitongluo granule was safe and effective in the treatment of stroke with qi - deficiency and blood - stasis syndrome.

  10. 四物汤合失笑散加味联合吲哚美辛治疗气滞血瘀型原发性痛经40例%Modified SiWuTang and ShiXiaoSan Combined with Indomatacin in Treating 40 Cases of Primary Dysmenorrhea of Qi Stagnation and Blood Stasis Pattern

    Institute of Scientific and Technical Information of China (English)

    刘丽萍

    2013-01-01

    目的:观察四物汤合失笑散加味联合吲哚美辛治疗气滞血瘀型原发性痛经的临床疗效.方法:将80例患者随机分为观察组和对照组各40 例.2 组患者均给予吲哚美辛治疗,25 mg/ 次,4 次/d,口服.观察组同时在月经来潮前5 天给予四物汤合失笑散加减,水煎分服,1 剂/d,经后2 天停药.2 组均以1 个月经周期为1 个治疗周期,连续治疗3个周期后观察疗效.结果:全血高切黏度(200/s)、低切黏度(3/s)、血浆黏度2组治疗后均较治疗前明显改善(P<0.05),且治疗后观察组与对照组相比差异显著(P<0.05).观察组治愈率为52.50%,总有效率为92.50%;对照组治愈率为35.00%,总有效率为77.50%,2 组相比差异显著(P<0.05).结论:四物汤合失笑散加味联合吲哚美辛治疗气滞血瘀型原发性痛经疗效显著.%Objective: To observe curative effects of modified SiWuTang and ShiXiaoSan combined with indomatacin in the treatment for primary dysmenorrhea of Qi stagnation and blood stasis pattern. Method: Eighty patients were randomly divided into the observation group and the control group. Both groups received oral indomatacin, 25 mg each time, 4 times each day. The observation group took modified SiWuTang and ShiXiaoSan in the five days of the periods, decocted with water, one dose each day, till the 2nd day when the period finished. One menstrual cycle was one course of treatment. Curative effects were explored after three consecutive courses of treatment. Result: Whole blood high shear viscosity (200/s), low shear viscosity (3/s) and plasma viscosity of both groups were improved after treating than before treating significantly (P<0.05), and the observation groups showed significant difference compared with the control group after treating (P<0.05). Cure rate and total effective rate of the observation group were 52.50% and 92.50% , superior to 35.00% and 77.50% of the control group with significant difference (P<0.05). Conclusion

  11. The Clinical Observation of Naoxinkang Capsule in the Treatment of Qi Deficiency,Blood and Phlegm Stagnation Syndrome of Ischemic Stroke Recovery Period of 56 Cases%脑欣康胶囊治疗气虚血瘀痰阻型缺血性中风恢复期56例疗效观察

    Institute of Scientific and Technical Information of China (English)

    孙玉勇

    2014-01-01

    Objective:To observe the clinical effect of Naoxinkang Capsule in the treatment of qi deficiency,blood and phlegm stagnation syndrome of ischemic stroke recovery period.Method:107 stroke patients with condition tends to be stable in our hospital from January 2011 to December 2012 were selected,using randomized,double-blind,double-dummy,parallel control study method,they were divided into the experimental group for 56 cases and the control group for 51 cases.The experimental group was given Naoxinkang Capsule for treatment,the control group was given Xuesaitong Tablets for treatment.The clinical efficacy and the changes of hemodynamics before and after treatment between the two groups were observed and compared.Result:After treatment,the total effective rate of experimental group was 87.50%(49/56),it was significantly higher than 70.59%(36/51) of control group,the difference was statistically significant(χ2=4.674,P=0.031).The hemodynamic indexes of the two groups after treatment were significantly lower than before treatment,and the hemodynamic indexes of experimental group after treatment were significantly lower than control group,the differences were statistically significant(P<0.05). Conclusion:Naoxinkang Capsule in the treatment of qi deficiency,blood and phlegm stagnation syndrome of ischemic stroke recovery period has the remarkable curative effect,safety and effectiveness,easy to use,is worthy of clinical promotion.%目的:观察脑欣康胶囊治疗气虚血瘀痰阻型缺血性中风恢复期的临床疗效。方法:选取2011年1月-2012年12月笔者所在医院收治的107例病情趋于稳定的中风患者作为研究对象,采用随机双盲、双模拟、平行对照研究方法将其分为试验组56例和对照组51例。试验组给予脑欣康胶囊治疗,对照组给予血塞通片治疗,观察比较两组患者的中医症候疗效及治疗前后血液动力学变化情况。结果:经治疗后,试验组的治疗总有效率87

  12. Clinical observation on constipation of qi-deficiency type by Buzhong Yiqi pills combined with biofeedback%补中益气丸联合生物反馈技术治疗气虚型便秘的临床研究

    Institute of Scientific and Technical Information of China (English)

    徐伟健; 吴建忠; 胡国金; 陈慧芳; 汤海红; 曾金明; 金方

    2012-01-01

    Objective To observe the clinical therapeutic effect of Buzhong Yiqi pills combined with biofeedback on constipation of qi-deficiency type. Methods 160 patients were randomized into four groups with 40 cases in each. The treatment group received Buzhong Yiqi pills combined with biofeedback therapy, and the control groups received Buzhong Yiqi pills, biofeedback, mosapride pills respectively. The Traditional Chinese Medicine(TCM) symptoms, the daily actions and the maximum surface electromyography (SEMG) of pelvic floor muscles were observed. Results Scores on TCM symptoms, daily actions and the SEMC of pelvic flour muscles of the four groups were different before and after the treatments (P < 0.05). The imforovement rates of the treatment group were higher than those of the control groups (P < 0.05). Conclusions Buzhong Yiqi pills combined with biofeedback therapy is effective in improving the TCM symptoms, daily actions and SEMG of pelvic floor muscles on constipation patients of qi-deficiency type.%目的 观察补中益气丸联合生物反馈技术治疗气虚型便秘的临床疗效. 方法 将160例患者随机分为4组,每组40例.治疗组予以补中益气丸联合生物反馈技术治疗,对照组分别予以补中益气丸、生物反馈技术、莫沙比利治疗,观测患者治疗前后的中医症状积分、行为方式积分及盆底肌表面肌电峰值,并评价疗效.结果 4组治疗前后的中医症状积分、行为方式积分、盆底肌表面肌电峰值比较的差异均有统计学意义(P<0.05).治疗组与对照组相比差异有统计学意义(P<0.05).改善盆底肌表面肌电方面,治疗组峰值提高率最高,且与其他组相比有明显差异. 结论 补中益气丸联合生物反馈技术可改善老年气虚型便秘患者中医症状、行为方式及盆底肌表面肌电峰值,临床疗效确切.

  13. Clinical observation of Pelvic floor electrical stimulation and biofeedback combined with buzhongyiqi decoction in the treatment of Qi -blood deficiency type uterine prolapse%盆底电刺激+生物反馈结合补中益气汤治疗气血虚弱型子宫脱垂的临床观察

    Institute of Scientific and Technical Information of China (English)

    谭快玲

    2014-01-01

    Objective To investigate the clinical effect of pelvic electric stimulation plus biofeedback combined with buzhongyiqi decoction in the treatment of Qi -blood deficiency type uterine prolapse .Methods 150 cases of Qi-blood deficiency type uterine prolapse patients , got therapy in our hospital during March 2010 and March 2013, were randomly divided into A, B and C group, 50 cases in each group.They were treated with three different methods respectively: buzhongyiqi decoction and Pelvic floor Kegel exercises , biofeedback and pelvic floor stimulation and Pelvic floor Kegel exercises , pelvic electric stimulation and biofeedback combined with buzhongyiqi decoction .Compared the total efficacy and vaginal muscle voltage .Results Total effective rate of group C (88%) was significantly higher than those of group A (52%) and group B (56%), the differences were statistically significant ( P 0.05 ).Compared with the vaginal muscle voltage before the treatment , differences were statistically significant ( P <0.01), and the differences between group C and group A/B were statistically significant (P<0.05).Conclusions The application of pelvic electric stimulation plus biofeedback combined with buzhongyiqi decoction achieved significant efficacy in the treatment of uterine prolapse , and vaginal muscle voltage changes significantly , it's worth of popularized and applied in clinic .%目的:探讨盆底电刺激+生物反馈结合补中益气汤治疗气血虚弱型子宫脱垂的临床效果。方法将2010年3月至2013年3月在我院门诊就医的150例气血虚弱型轻中度子宫脱垂患者随机分为A、B、C三组,各为50例,分别给予补中益气汤+盆底凯格尔运动、盆底电刺激+生物反馈+盆底凯格尔运动、盆底电刺激+生物反馈结合补中益气汤对其进行治疗,比较三组临床治疗总有效率及治疗前后阴道肌电压。结果 A、B、C三组治疗总有效率分别为52.00%、56.00%、88.00

  14. 针刺疗法配合琥珀散加减治疗气滞血瘀型卵巢巧克力样囊肿30例%Acupuncture Combined with Amber Powder in the Treatment of 30 Cases of Ovarian Chocolate Cyst with Qi Stagnation and Blood Stasis Type

    Institute of Scientific and Technical Information of China (English)

    韩凤娟; 盛霄燕; 田苗; 周扬; 王秀霞

    2015-01-01

    目的:探究针药结合治疗气滞血瘀型卵巢巧克力样囊肿的临床疗效。方法:60例符合诊断标准的气滞血瘀型卵巢巧克力样囊肿患者随机分为治疗组和对照组。对照组30例给予中药琥珀散加减治疗,治疗组30例在对照组的基础上加针刺治疗,连续用药3个月,经期停止治疗。观察两组治疗前后临床疗效、症状改善情况。结果:两组均可明显缓解患者的临床症状,治疗组和对照组总有效率分别为86.7%和76.7%,治疗组的临床疗效、症状改善情况优于对照组,且复发率和副反应的发生率低于对照组( P<0.05)。结论:针刺疗法配合琥珀散加减治疗气滞血瘀型卵巢巧克力样囊肿,症状明显改善,临床疗效满意。%Objective:To investigate the clinical efficacy of acupuncture combined with Amber powder on ovari-an chocolate cyst with Qi stagnation and blood stasis type.Methods:60 patients met the diagnostic criteria were randomly divided into treatment and control groups.The control group including 30 patients was given medicine Amber powder treatment,and the treatment group including 30 patients was on the basis of treatment in the con-trol group plus acupuncture,with continuous medication for 3 months and menstruation to stop treatment.Ob-serve the clinical efficacy, improvement of symptoms before and after treatment.Results:The two groups could significantly alleviate the clinical symptoms,and in the treatment group and the control group the total effective rates were 86.7%and 76.7%respectively.The clinical efficacy in the treatment group was better than that in the control group, and the relapse rate and incidence of side effects were lower than those in the control group ( P<0 .05 ) .Conclusion:Acupuncture with Amber powder for ovarian chocolate cyst with Qi stagnation and blood stasis type has a satisfactory efficacy,which can improve the symptoms obviously.

  15. Clinical Research of Supplementing Qi and Nourishing Yin,Removing Toxin and Activating Blood Circulation Method in Treating Acute Coronary Syndrome%益气养阴、解毒活血法治疗急性冠脉综合征临床研究

    Institute of Scientific and Technical Information of China (English)

    陈曦

    2015-01-01

    目的:观察益气养阴、解毒活血法治疗急性冠脉综合征的临床疗效。方法:将120例急性冠脉综合征患者随机分为治疗组和对照组,每组各60例,对照组采用西医常规治疗,治疗组在对照组基础上加服自拟中药方,治疗4周后观察两组临床疗效,两组患者心电图疗效、两组患者中医证候积分、血清基质金属蛋白酶-7、热休克蛋白60水平的变化。结果:两组患者临床疗效比较,治疗组有效率为95.0%,对照组有效率为86.7%,差异有统计学意义(P <0.05)。治疗组在提高心电图疗效,降低中医证候积分、降低血清基质金属蛋白酶-7和热休克蛋白60水平方面显著优于对照组,具有统计学意义(P <0.01或 P <0.05)。结论:益气养阴、解毒活血法疗在改善患者临床症状和心电图表现,减轻急性冠脉综合征发病的炎性反应、降低斑块的不稳定性方面疗效显著。%Objective:To observe the effect of supplementing Qi and nourishing Yin,removing toxin and activating blood circulation method in treating acute coronary syndrome.Methods:1 20 cases of acute coronary syndrome patients were randomly divided into treat-ment group and control group,60 cases in each group.The control group was treated with routine western medicine and treatment group was given Chinese herbal medicine based on control group.After 4 weeks of treatment,observe the clinical efficacy of the two groups, ECG curative effect of two groups of patients,two groups of patients with TCMsymptoms integral,serum levels of matrix metalloprotein-ase-7 and heat shock protein 60 levels.Results:The clinical efficacy was 95.0% in treatment group and 86.7% in control group,the difference was statistically significant(P <0.05).Combined with traditional Chinese medicine treatment group in improving the effect of electrocardiogram(ECG),reduce TCMsyndrome integral,reduce serum matrix metalloproteinase

  16. Effect of Regulating Liver-Qi and Tonifying Kidney Formula on CaMKⅡ in CA1 Region of Hippocampus in Fatigue Rats%疲劳大鼠经疏肝补肾方用药后海马CaMK Ⅱ水平的变化

    Institute of Scientific and Technical Information of China (English)

    马佳美; 李峰; 宋月晗; 范新六; 王丽晔; 许展嘉; 郭思媛

    2011-01-01

    Objective To study effect of regulating liver-Qi and tonifying kidney formula(RLTKF) on Ca/calmodulin dependent protein kinases Ⅱ (CaMK Ⅱ ) level in the CA1 region of hippocampus in fatigue rats.Methods Thirty - six male adult Spargue - Dawley rats were randomly divided into three groups:Model group (n= 12), control group (n = 12) and RLTKF group (n = 12).Fatigue models were established by exercise fatigue and sleep deprivation.Y maze was used to test the memory and learning of the rats.The CaMK Ⅱ expression in CA1 region of hippocampus was tested by western blot and real - time PCR.Results The ability of memory and learning in rats in RLTKF group was better than that in model group.The correct response rate, times of error reaction were significant difference between RLTKF group and model group(P<0.01).The expression of phosphorylated CaMK Ⅱ was lower in model group than that in control group (P<0.01).It was higher in RLTKF group than that in model group (P<0.01).There are also significant difference on CaMK Ⅱ mRNA expression in model group and RLTKF group with control group (P<0.05).Conclusion Fatigue could decrease the level of CaMK Ⅱ in the CA1 region of hippocampus,which could be ameliorated by RLTKF.The damage of learning and memory caused by fatigue could be antagonized through regulating liver - Qi and tonifying kidney therapy.%目的 研究疏肝补肾方药对于疲劳大鼠海马CA1区钙/钙调蛋白依赖性激酶Ⅱ(CaMK Ⅱ)水平的变化.方法 成年雄性Spargue-Dawley大鼠36只,随机分为模型组、对照组、疏肝补肾组.应用大鼠游泳运动结合睡眠剥夺建立疲劳大鼠复合模型,以Y迷宫实验评定其学习记忆能力.取大鼠海马CA1区以Western Blot定量检测,并以Real-time PCR技术分析海马CA1区CaMK Ⅱ的mRNA表达.结果 Y迷宫实验显示用药后大鼠的学习和记忆能力优于模型组,而疏肝补肾组大鼠在正确反应率和错误反应次数皆与模型

  17. Effect of Keyu Shushen Granule on Brain-derived Neurotrophic Factor in Hippovampus in Rats with Experimental Dysthymia and Stagnation of Liver-qi Syndrome%克郁舒神颗粒对实验性恶劣心境肝气郁结证大鼠海马BDNF的影响

    Institute of Scientific and Technical Information of China (English)

    衣春光; 李方莲; 张茂云; 王健

    2011-01-01

    Objective:To observe the effect of Keyu Shushen granule on the brain-derived neurotrophic factor(BDNF) in the hippocampus for experimental dysthymia and stagnation of liver-qi syndrome in rat. Method:Sixty male rats were randomly divided into six groups: control, model, Keyu Shushen granule ( 1.50,0. 75,0. 375 g·kg-1) ,fluoxetine( 10 in each group). The rats were put under chronic unpredictable mild stress and separately raised,in order to induce the model of dysthymia. Immunohistochemical method was used to examine the expression of BDNF in the hippocampus of rat. Result: Compared with those in control group, BDNF positive neurons in the hippocampus of rat were decreased obviously in the model group. After treatment, the area ratio of BDNF positive neurons in The Keyu Shushen granule (low dose, middle dose)on experimental dysthymia stagnation of liver-qi syndrome rat was improved. It was exceeded that of the fluoxetine group ( P < 0.01 ). Difference between middle dose and low dose had no statistical significance. Conclusion:Decrease of the BDNF positive neurons in hippocampus in rat is one of the mechanisms responsible for the dysthymia stagnation disease Keyu Shushen granule can increase the content of BDNF in hippocampus with better efficacy compared to fluoxetine.%目的:研究克郁舒神颗粒对实验性恶劣心境肝气郁结证大鼠海马脑源性神经营养因子(BDNF)的影响.方法:选择60只雄性Wistar大鼠,随机分为空白组、模型组、克郁舒神颗粒高、中、低(1.50,0.75,0.375 g·kg-1)剂量组和氟西汀组,每组10只.采用慢性不可预见的温和性应激和孤养方法制备实验性恶劣心境肝气郁结证大鼠模型.应用免疫组织化学法检测大鼠海马BDNF蛋白表达水平.结果:与空白组比较,模型组大鼠大脑海马BDNF阳性神经元细胞明显减少,克郁舒神颗粒中、低剂量可以提高BDNF阳性神经元的面积比,优于高剂量组及氟西汀组(P<0.01);中、低剂量组

  18. The influence of replenishing qi to nourish yin method on the quality of life of gastric car-cinoma postoperation and chemoradiotherapy patients%益气养阴法对胃癌术后同步放化疗患者生活质量的影响

    Institute of Scientific and Technical Information of China (English)

    刘瑜; 袁媛; 张蕊; 李毅; 庞宏涛; 王蓓莉

    2015-01-01

    Objective:To investigate the influence of replenishing qi to nourish yin method on the quality of life, the gastrointestinal toxicity and hematological toxicity on gastric carcinoma postoperation and chemoradiotherapy pa-tients.Methods:All 62 gastric carcinoma postoperation patients accepted chemoradiotherapy were randomly divided into two groups.The treated group (chemoradiotherapy +traditional Chinese medicine group)were 34 patients and 28 patients in the control group (chemoradiotherapy group).The quality of life was scored before and after treatment and all levels of the gastrointestinal toxicity and hematological toxicity was calculated.Results:QLQ C30 evaluation:After treatment ,the score of AP,FA and SL of the treated group was lower than the the control group,the PF and QL score was higher than the control group,P <0.05.The Ⅲ/Ⅳ incidence of hematological and gastrointestinal toxicity of the treated group was lower than the the control group,P <0.05.Conclusion:Compared with the control group,replenis-hing qi to nourish yin method on gastric carcinoma patients postoperation who accepted chemoradiotherapy can im-prove the the symptoms of appetite loss,fatigue and sleep,improve the physical function and quality of life,reduce moderate -severe occurrence rate of the gastrointestinal and hematological toxicity.There was certain curative effect on prevention and control of side effects of the chemoradiotherapy.%目的:观察益气养阴法对胃癌术后进行同步放化疗患者骨髓毒性、消化道毒性及生活质量的影响。方法:将62例胃癌术后进行同步放化疗的患者随机分为治疗组(同步放化+中药组)34例,对照组(同步放化疗组)28例,治疗前后进行肿瘤患者生活质量评分,治疗后计算各级骨髓毒性、消化道毒性患者比例。结果:QLQ -C30评定:治疗后治疗组食欲下降、疲倦、失眠评分低于对照组,P <0.05。肿瘤患者躯体症状、总体健康

  19. Clinical Study on the Treatment of Hyperlipoidemia of Qi Stagnation and Blood Stasis Type by Liqi Huoxue Huazhuo Decoction%理气活血化浊汤治疗气血瘀滞型高脂血症临床研究

    Institute of Scientific and Technical Information of China (English)

    张太

    2012-01-01

    目的:探讨理气活血化浊汤治疗气血瘀滞型高脂血症的临床疗效.方法:将115例患者按照就诊先后顺序,用随机数字表法,分为两组.治疗组70例,采用理气活血化浊汤(方药组成:当归10 g,赤芍15 g,川芎10 g,桃仁10 g,红花15 g,水蛭6 g,酒大黄10 g,泽泻12 g,山楂30 g,决明子30 g,陈皮10 g,何首乌30 g,茯苓15 g,丹参15 g),每日1剂;对照组45例,采用脂必妥片,每日3次,1次3片,口服.所有患者均8周为1个疗程,疗程结束后统计疗效.结果:治疗组有效率为90.00%,对照组有效率为68.89%,两组比较:x2=8.179,v=1,P=0.004<0.05,差异有统计学意义,治疗组显著优于对照组;患者均按时完成研究,显示出药物良好的依从性,观察中未发现药物有明显不良反应.结论:理气活血化浊汤治疗气血瘀滞型高脂血症有较好的临床疗效.%Objective:To study the clinical effects of Liqi Huoxue Huazhuo Decoction on the treatment of hyperlipoidemia of qi stagnation and blood stasis type. Methods: 115 patients were divided into two groups by the method of random number table according to the sequence of treatment. The treatment(70 cases) was treated by Liqi Huoxue Huazhuo Decoction (Prescription components: angelica 10 g, red peony root 15 g,Chuanxiong 10 g,peach kernel 10 g,the Safflower 15 g,leech 6 g,wined rhubarb 10 g,Alisma 12 g,the haw 30 g, cassia seed 30 g,dried tangerine peel 10 g,fleece -flower root 30 g,Poria 15 g,Salvia 15 g) ,one dosage per day;the control group(45 cases ) was given Zhibituo tablet, three times one day with three tablets each time. All patients in both groups were treated for one course of 8 weeks and therapeutic effects were analyzed after one course of treatment. Results: Effective rate of the treatment group was 90. 00% .while the control group was 68. 89% . Comparison between both groups showed their difference had statistical significance,and the treatment group was superior to the control group (x2 =8

  20. Effect of Yi Qi Fu Mai (YQFM) (Lyophilized) on the Activity of Hepatic CYP1 A2 and CYP3A in Rats%Cocktail法评价注射用益气复脉(冻干)对大鼠肝微粒体CYP1A2、CYP3A的诱导作用

    Institute of Scientific and Technical Information of China (English)

    胡冰; 岳洁皓; 段超慧; 叶正良; 周大铮; 李德坤; 马英丽

    2012-01-01

    Objective: To investigate the effect of Yi Qi Fu Mai Injection (YQFM) (Lyophilized) on the activity of cyto-chrome P450 (CYP1A2, CYP3A) in rats. Method: Healthy wistar rats raised ethically were pretreated with YOFM(Lo-phhilized) via the caudal vein once daily for consecutive seven days, and then hepatic microsomes were prepared. A cocktail selective substrates consisting of the phenacetin (PN,CYP1A2) and testosterone (TS,CYP3A) was incubated with rat livermicrosomes. Determined by HPLC method, the formation rates of acetaminophen and 6β-OH testosterone, the metabolites of the probe drugs were used as an indicator to estimate the activity of CYP1A2 and CYP3A. Result: The formation rates of acetaminophen were(18.04 ± 1.00) ,(43. 07 ±2.90) , (27. 6 ±4. 5) ng o ( mg protein)-1 min-1 ,The formation rates of 6β -OH testosterone were(15.79 ± 1.43 ) , (40. 86 ± 3. 32) , (32. 8 ± 3. 67 ) ng o ( mg protein) -1 o min-1. Conclusion; YQFM has an induced effect on the activity of CYP1A2 and CYP3A.%目的:研究注射用益气复脉(冻干)Yi Qi Fu Mai Injection( YQFM) (Lyophilized)对大鼠肝微粒体CYP1A2、CYP3A的诱导作用.方法:将wistar大鼠分为生理盐水对照组,苯巴比妥钠诱导组,YQFM组,连续给药7天后处死,制备肝微粒体.采用Cocktail法,将特异性探针底物非那西丁(CYP1A2)、睾酮(CYP3A)与肝微粒体共孵育,采用高效液相色谱测定孵育所得代谢产物对乙酰氨基酚和6β一羟基睾酮的生成速率,来评价YQFM对CYP1A2、CYP3A的诱导作用.结果:空白对照组、诱导组和YQFM组的对乙酰氨基酚的生成速率分别为(18.04±1.00)、(43.07±2.90)、(27.6±4.5) ng·(mg protein)-1·min-1,6β-羟基睾酮的生成速率分别为(15.79±1.43)、(40.86±3.32)、(32.8±3.67 )ng·(mg protein) -1·min -1.结论:YQFM对大鼠肝微粒体CYP1A2、CYP3A有诱导作用.

  1. Consideration between “Tao” and “Qi ” Recording the Thoughts of the Longquan Celadon Museum Design%斟酌于“道”、“器”之间——龙泉青瓷博物馆方案设计中的思考

    Institute of Scientific and Technical Information of China (English)

    刘鹏飞; 殷建栋

    2012-01-01

    该文通过对程泰宁院士及其创作团队的设计作品龙泉青瓷博物馆方案的创作过程的记叙,探讨中国传统“道”“器”哲学思想,作为一种可依循的设计思考途径在当代建筑设计中的应用.笔者从中国传统哲学谈起,以阐释建筑本源作为思维的主线,将发掘建筑的精神意义作为目标,以记叙设计中方案推敲的过程为方法,将程院士在建筑设计中和设计外的一些思索揭示出来.借此设计案例的分析,展示了中国哲学在建筑设计领域中的发展与魅力.%This article describes the generation process of the Longquan celadon museum scheme which is designed by Cheng Taining academician and his teams. In that case, we could try to probe the possibility of using the Chinese traditional "Tao and Qi" philosophy as the thinking approach in the modern architecture design. The article starts from the Chinese traditional philosophy, explains the fontal architecture as the thinking line, explores the spiritual significance of architecture as the target, narrating process of scrutiny by the design program for the method, all above is the way to reveal Mr. Cheng1 thoughts of the process of design. This design case analysis shows the development and charm of the Chinese philosophy in the field of architecture design.

  2. On Prescription of Warming Yang and Invigorating Qi Combined with Levocarnitine in Improving Phlegm-dampness Pattern during Fasting Period%温阳补气联合左卡尼汀改善禁食期间痰湿证初探

    Institute of Scientific and Technical Information of China (English)

    张俊杰; 孟君; 柯斌; 杨玉彬; 石兰英; 邱超平; 秦鉴

    2014-01-01

    通过典型案例指出禁食疗法具有减轻体重、改善胰岛素抵抗及降低炎症反应等作用,能够有效治疗超重/肥胖相关的代谢性疾病,但禁食期间人体易出现饥饿、乏力、头晕及反应迟钝等不适反应,限制了禁食疗法的临床应用,但根据禁食期间中医证型表现,结合禁食下能量代谢改变,使用温阳补气方联合左卡尼汀干预禁食,结果发现饥饿、倦怠乏力、头晕及反应迟钝等不适反应发生率显著下降,饥饿耐受性显著提高。%Fasting therapy could reduce the weight, improve insulin resistance and alleviate inflammations, which could be applied to the treatment for overweight/obesity related metabolic diseases. Its clinical application was restricted due to the patients' side effects including hunger, fatigue, vertigo and slow response, the prescription of warming Yang and invigorating Qi and levocarnitine were used to intervene fasting according to the manifestations of TCM pattern and the changes of energy metabolism in fasting period, it's found that the incidence of side effect such as hunger, fatigue, vertigo and slow response was lowered and hunger tolerance was raised remarkably.

  3. 清热利湿、益气养血法治疗皮肤变性皮损型糖尿病足的理论与临床(附1例报告)%Theory and clinical of clearing heat and promoting diuresis and Yi Qi Yang Xue method in the treatment of skin degeneration skin lesions type diabetic foot

    Institute of Scientific and Technical Information of China (English)

    高玉魁

    2015-01-01

    糖尿病是一种目前无法治愈的慢性疾病,具有庞大的“患者群”和“后备军”,同时有心、脑、肾、血管、视网膜、足部等并发症。因此,要加强糖尿病治疗的“三早”措施,即早发现、早诊断、早治疗。运用中西医结合的清热利湿、益气养血的治法效果良好。科学地治疗、积极改善生活方式,对糖尿病一级、二级预防都有很大现实意义,不仅要控制血糖,更重要的是对患者进行全面的人文关怀,才能为患者提供科学的指导和治疗。%Diabetes is a incurable chronic diseases at present,the incidence has the huge “patient group” and “reserve army”,at the same time it has the heart,brain,kidney,blood vessels,retinal,foot and other complications.Therefore,it should strengthen“three early”measures in the treatment of diabetes,namely the early discovery,early diagnosis,early treatment.The use of traditional Chinese and western medicine combination of clearing heat and promoting diuresis and Yi Qi Yang Xue method have good effect.Scientific treatment,actively improving the lifestyle have great practical significance on the primary and secondary prevention of diabetes.Not only to control blood sugar,it is more important to comprehensive humanistic care for patients to provide scientific guidance and treatment for patients.

  4. Pro.Yang Huimin's Experience in Treating Spontaneous Perspiration with Method of Tonifying Qi Nourishing Yin to Consolidate Surface and Arrest Sweating%杨惠民教授益气滋阴固表敛汗法治疗自汗经验浅谈

    Institute of Scientific and Technical Information of China (English)

    冯一; 杨惠民

    2013-01-01

    [Objective] To sum up Pro. Yang Huimin's academic ideas and clinical experience in treating spontaneous perspiration. [Method] It respectively expounds his academic ideas and clinical experience from clinical demonstrations, causa morbi and treatment based on differentiation of signs, meanwhile, and summarizes his unique points of medication on symptoms and telling patients to work and rest abiding by Yin Yang rule. [Result] The disease mechanism is stressed on weak lung function, esp. misbalanced Yinyang and loose flesh texture; thereby Pro. Yang Huimin sums up the treatment rule of tonifying Qi nourishing Yin to consolidate surface and arrest sweating. [Conclusion] Pro. Yang Huimin's method has good clinical efficacy, with value of promotion for application.%[目的]总结杨惠民教授治疗自汗的学术观点和临床经验.[方法]分别从临床表现、病因病机、辩证施治方面论述杨惠民教授治疗自汗的学术观点和临床经验,同时总结杨惠民教授因症用药及嘱患者顺应阴阳安排作息等独特之处.[结果]本病发病病因偏重于肺卫薄弱,病机突出于阴阳失调、腠理不固,以”肺卫不固”多见,根据以上病因病机,杨惠民教授总结出益气滋阴固表敛汗的治则.[结论]杨惠民教授益气滋阴固表敛汗法在自汗的临床治疗效果显著,具有推广应用价值.

  5. Clinical study on treatment of rheumatoid arthritis of cold dampness obstruction and kidney yang qi deficiency with Juanbi granulae%蠲痹颗粒用于寒湿痹阻和肾气虚寒型类风湿关节炎的临床疗效观察

    Institute of Scientific and Technical Information of China (English)

    崔世奎

    2012-01-01

    Objective To observe the effect of Juanbi granulae on rheumatoid arthritis belonging to cold dampness obstruction and kidney yang qi deficiency syndrome.Methods All 120 RA patients in accordance with the inclusion criteria were divided into a 80 cases of study group,and a 40 cases of control group,by random table method.Methotrexate,10mg once a week,was given orally,as a basis for treatment.The treatment group given Juanbi granulae,15g for each time,3 times a day; while the control group was Zhenqingfengtongning sustained-release tablets,60mg for each time,twice daily.Both groups have adopted a one-month course of treatment.Statistics effect was evaluated after 4-week course of treatment.Results ①There was significant difference between the two group in terms of therapeutic effects and symptom effects after the treatment (the total effective rate of study group and control group was 100.0%,86.7%,U value was-4.071,-3.232 respectively,P<0.05).② The treatment effects and the symptom effect of the cold dampness syndrome and the kidney yang qi deficiency syndrome in the same group showed statistical difference after the treatment (the total effective rate of study group and control group was 88.0%,80.0%,The U value of treatment effect was-5.50,-3.67 respectively,P<0.01 or P<0.05).(U value of syndrome effect was-2.909,-3.992 respectively,P<0.05).③ Study group of after treatment ESR (17.05±7.15) mm/h,RF (32.46± 14.22) U/L,compared with the control group of after treatment,the difference was statistically significant (P<0.05).Conclusion Juanbi granulae was effective in treating rheumatoid arthritis of both kidney yang qi deficiency syndrome and cold dampness obstruction syndrome,the effects were especially better for cold dampness obstruction syndrome.%目的 初步评价蠲痹颗粒对寒湿痹阻和肾气虚寒型类风湿关节炎(rheumatoid arthritis,RA)的临床疗效.方法 采用随机数字表法将全部RA患者随机分为治疗组80

  6. 益气活血中药对放射性肺损伤大鼠NOS3、MTHFR表达的影响%Effect of Supplementing Qi and Activating Blood Circulation of Traditional Chinese Drugs on Expressions of NOS3 and MTHFR in Rats with Radiation Induced Lung Injury

    Institute of Scientific and Technical Information of China (English)

    焦静; 王炳胜; 刘斌; 张海; 刘秀芳; 赵增虎

    2016-01-01

    目的:探讨益气活血方防治放射性肺损伤的分子生物学机制和相关敏感因子。方法将108只雌性SD大鼠采用随机数字表法分为中药组(A组)、单纯照射组(B组)及健康对照组(C组),每组36只。应用6MV-X直线加速器对前2组大鼠右肺进行照射(5 Gy/次,2次/周,累积剂量为30 Gy),A组于受照射当天开始用益气活血方1 ml灌胃、2/d,B组及C组用蒸馏水1 ml灌胃、2/d,停止时间为照射结束后2周。各组于照射开始第2、4、8、12、16、20周末随机抽取6只大鼠处死,取其肺组织,用反转录-聚合酶链反应( RT-PCR)及免疫组化方法检测大鼠肺组织内皮型一氧化氮合酶(NOS3)、亚甲基四氢叶酸还原酶(MTHFR)mRNA及蛋白表达。结果 A组与B组NOS3、MTHFR的mRNA及蛋白表达于照射后第2周开始增高,第8周达高峰,第12周开始下降,16周后降低明显,与C组相比,差异均有统计学意义(P<0.01);A组与B组相比,NOS3、MTHFR mRNA及蛋白表达趋势类似,A组表达水平在12周之前均高于B组,差异有统计学意义(P<0.05,P<0.01)。结论 NOS3、MTHFR可能为放射性肺损伤的敏感因子。益气活血方可通过上调NOS3、MTHFR的表达起到减轻放射性肺损伤的作用。临床放射性肺损伤治疗时间应延长2~3个月,各时间段治疗重点应有所侧重。%Objective To investigate the molecular biological mechanisms and related sensitive factors of sup-plementing Qi and activating blood circulation of traditional Chinese drug in prevention and treatment of radiation induced lung injury ( RILI) . Methods A total of 108 SD male rats were divided into traditional Chinese drugs group ( group A, n=36), only irradiation group (group B, n=36) and healthy control group (group C, n=36) with random digits ta-ble. Group A and B were irradiated by 6MV-X linear accelerator on right lung with 30 Gy accumulated dose (5 Gy/time, 2 times/week). On the 1st d of radiation, group A was gavaged with 1

  7. Therapeutic Effect of Huazhuo Detoxification Fumigation for Qi Stagnation and Blood Stasis Type Chloasma and Its Influence on the Levels of Serum Estradiol%化浊解毒熏蒸法治疗气滞血瘀型黄褐斑的效果及对血清雌二醇水平的影响

    Institute of Scientific and Technical Information of China (English)

    王丽丽; 张金虎; 朱胜君

    2013-01-01

    目的 探讨化浊解毒熏蒸法对气滞血瘀型黄褐斑的治疗效果及其对血清雌二醇(E2)水平的影响.方法 选取2008年6月-2012年6月我院康复科收治的黄褐斑患者104例,中医辨证均属气滞血瘀型.按随机数字表法将患者随机分为对照组和治疗组,各52例.治疗组:采用自拟化浊解毒方,浓煎取汁500 ml,放到中药汽疗仪的蒸锅中加热,产生雾气后,嘱患者穿短袖衣裤进入汽疗舱,温度设定在38 ℃,每次熏蒸30 min,1次/d,10 d为1个疗程,连续2个疗程,每个疗程间隔5 d.对照组:将蒸馏水加入到汽疗仪的蒸锅中加热,熏蒸方法、疗程同治疗组.同时两组患者口服排毒养颜胶囊,0.8 g/次,2次/d,30 d为1个疗程.治疗后,对两组的临床疗效及治疗前后空腹静脉血E2水平进行比较.等级资料比较采用秩和检验,计量资料比较采用t检验.结果 治疗后,对照组基本治愈5例,显效9例,好转13例,无效25例;治疗组基本治愈27例,显效13例,好转8例,无效4例,两组疗效比较差异有统计学意义(u=993.5,P=0.017).治疗前对照组、治疗组患者血清E2水平分别为(91.3±2.1)ng/L和(92.6±2.2)ng/L,组间比较差异无统计学意义(P>0.05);而治疗后治疗组患者血清E2水平(62.1±1.7)ng/L低于对照组的(71.2±2.0)ng/L,组间比较差异有统计学意义(P<0.05).结论 化浊解毒熏蒸法治疗能明显降低气滞血瘀型黄褐斑患者血清E2水平,有较好的临床疗效,适合临床推广.%Objective To explore the therapeutic effect of Huazhuo Jiedu fumigation for qi stagnation and blood stasis type chloasma and its influence on the levels of serum estradiol ( E2 ) . Methods A total of 104 patients with qi stagnation and blood stasis type chloasma TCM in the rehabilitation of our hospital from June 2008 to June 2012 were analyzed. According to the random number table, these patients were randomly and evenly divided into control group and treatment group. The treatment

  8. 降香舒心胶囊对气滞血瘀型不稳定型心绞痛患者血管内皮功能的影响%Effects of Jiangxiang Shuxin Capsules on Endothelial Function in Patients with Unstable Angina Pectoris of Qi Stagnation and Blood Stasis Type

    Institute of Scientific and Technical Information of China (English)

    常智玲; 何江; 李溥; 管慧; 周锦勇; 李世红; 廖沙; 阳淑芳

    2012-01-01

    目的:探讨降香舒心胶囊对气滞血瘀型不稳定型心绞痛的临床疗效及血管内皮功能的影响.方法:采用随机双盲安慰剂对照试验设计方法,选择158例气滞血瘀型不稳定型心绞痛患者随机分为治疗组81例和对照组77例,两组均采用最佳西医治疗方案,治疗组在西医治疗基础上口服降香舒心胶囊(4粒/次,3次/d),对照组口服安慰剂胶囊(4粒/次,3次/d).治疗疗程均为8周.并观察两组患者治疗前后心绞痛发作、中医证候以及检测血清一氧化氮(NO)、内皮素(ET)、血管性血友病因子(vWF)、超氧化物歧化酶(SOD)、丙二醛(MDA)水平及肱动脉血流介导的血管扩张变化率(FMD).结果:治疗组与对照组心绞痛缓解总有效率分别为93.82%,68.83%,中医症状疗效总有效率分别为98.76%,66.23%;两组患者胸痛、胸闷、气短、心悸等各单项评分及总分与治疗前比较均降低(P<0.01).治疗组与对照组比较,差异有统计学意义(P<0.05);与治疗前比较,治疗后两组患者血清ET,vWF降低,NO,FMD均升高(P<0.01)).治疗组血清SOD水平明显升高,MDA水平显著下降(P<0.01),而对照组SOD和MDA水平无变化.结论:降香舒心胶囊能改善气滞血瘀型不稳定型心绞痛患者临床症状和血管内皮功能,是安全有效的辅助治疗药物.其机制可能与抗脂质过氧化作用有关.%Objective: To investigate the effect of Jiangxiang Shuxin capsules on vascular endothelium in patients with unstable angina pectoris ( UAP) of Qi stagnation and blood stasis type. Method; A design of randomized, placebo-controlled, double-blind trial was adopted; 158 cases of UAP of Qi stagnation and blood stasis type were selected and randomly divided into treatment group and control group, with 81 cases in treatment group and 77 in control group. The best western medical therapy solution was applied to both groups, on which basis Jiangxiang Shuxin capsules and placebo capsules

  9. 舒肝解郁胶囊对肝气郁滞型经行乳房胀痛临床症状的改善及疗效观察%Observation of the symptom improvements of Shugan - jieyu capsules on breast distending pain during men-struation with liverˊs qi stasis type and its curative effect

    Institute of Scientific and Technical Information of China (English)

    吴欢

    2016-01-01

    Objective To observe the clinical effects of Shugan - jieyu capsules on the treatment of breast distending pain during menstruation with liverˊs qi stasis type. Methods 60 breast distending pain during menstrua-tion patients with liverˊs qi stasis type were randomly divided into two groups. 30 subjects in control group were treated by Xiaoyao pills. 30 subjects in treatment group were treated by Shugan - jieyu capsules. The curative effect was e-valuated 2 months after treatment in two groups. The quantized integrations of breast distending pain and out of sorts before and 1,2 months after treatment were compared in two groups. Results After treatment for 1 month,the total effective rate in treatment group and control group was 51. 85% and 30. 77% respectively,with no statistical signifi-cance(P ﹥ 0. 05). After treatment for 2 months,the total effective rate in treatment group(81. 48% )was superior to that in control group(50. 00% ,P ﹤ 0. 05). The scores of breast distending pain and out of sorts 1 and 2 months after treatment in treatment group were obviously decreased as compared with those in before treatment(P ﹤ 0. 05), and the decrease in 2 months after treatment was more significantly(P ﹤ 0. 05). The out of sorts scores 1 and 2 months after treatment in control group were obviously decreased as compared with those in before treatment(P ﹤0. 05),and the decrease in 2 months after treatment was more significantly(P ﹤ 0. 05). The score of breast disten-ding pain after treatment in control group was decreased,but with no statistical significance(P ﹥ 0. 05). The scores of breast distending pain and out of sorts before and 1,2 months after treatment in treatment were lower than those in control group at the same period(P ﹤ 0. 05). Conclusion Shugan - jieyu capsules has exact effect on the treatment of breast distending pain during menstruation with liverˊs qi stasis type,can obviously improve the symptoms of breast distending pain and out of sorts

  10. Analysis on the application of self-made detoxication, tonifying Qi and removing dampness prescription in chronic cervicitis combined with human papillomavirus infection after LEEP%自拟解毒补气利湿方在慢性宫颈炎并发人乳头状瘤病毒感染LEEP术后的应用分析

    Institute of Scientific and Technical Information of China (English)

    郭秀云

    2016-01-01

    Objective To explore the clinical efficacy of self-made detoxication,tonifying Qi and removing dampness prescription in treatment of chronic cervicitis combined with human papillomavirus (HPV) infection after loop electrosurgical excision procedure (LEEP).Methods Eighty-four patients with chronic cervicitis combined with HPV infection were selected from the hospital from January to December in 2014,then the patients were randomly divided into group A and group B,42 patients in each group.The patients in the two groups were treated by LEEP,and the patients in group A were treated by self-made detoxication,tonifying Qi and removing dampness prescription after LEEP.The clinical effects,high-risk HPV loads,changes of tumor necrosis factor-α (TNF-α) and interleukin-6 (IL-6),the incidence rates of adverse reactions in the two groups were compared.Results The total clinical effective rates in group A and group B were 80.95% and 54.76%,respectively,there was statistically significant difference between the two groups (P<0.05).The incidence rates of adverse reactions in group A and group B were 7.1% and 23.8%,respectively,there was statistically significant difference between the two groups (P<0.05).Before treatment,there was no statistically significant difference in high-risk HPV load,TNF-α and IL-6 levels between the two groups (P>0.05);at 15 days after treatment,high-risk HPV loads,TNF-α and IL-6 levels in the two groups decreased significantly (P<0.05),especially in group A (P<0.05).Conclusion Self-made detoxication,tonifying Qi and removing dampness prescription can significantly reduce high-risk HPV load and TNF-α,IL-6 levels of patients with chronic cervicitis combined with HPV infection after LEEP,the clinical efficacy is good,the incidence rates of adverse reactions are low,so the clinical application value is high.%目的 探讨自拟解毒补气利湿方治疗慢性宫颈炎并发人乳头状瘤病毒(HPV)感染超高频电波刀(LEEP

  11. 益气清瘟解毒颗粒剂治疗流行性感冒的临床疗效评价%Clinical Effect of Granules for Qi-Refreshing and Pestilence-Eliminating-Detoxifying in Treatment of Influenza

    Institute of Scientific and Technical Information of China (English)

    徐红日; 程淼; 殷人易; 徐丽丽; 于会勇; 王明哲; 姜良铎; 周平安; 王成祥; 刘清泉; 王兰; 张立山; 寇兰俊; 李雁; 刘涓; 苗青; 郭楠

    2012-01-01

    目的 评价益气清瘟解毒颗粒剂治疗流行性感冒的有效性和安全性.方法 将临床收集的123例表寒里热型流行性感冒患者随机分为中药治疗组与西药对照组,中药治疗组口服益气清瘟解毒颗粒剂,西药对照组服用抗病毒药治疗.结果 益气清瘟解毒颗粒剂的退热效果优于西药对照组,中药治疗组改善流感患者的症状积分优于西药抗病毒药物,其疾病疗效、中医证候疗效及主要症状疗效均优于西药对照组,且具有抑制免疫炎性损伤的趋势.结论 益气清瘟解毒颗粒剂治疗表寒里热型流行性感冒疗效显著,安全可靠.%Objective To estimate the effect and safety of Granules for Qi - Refreshing and Pestilence - Eliminating -Detoxifying ( GQPD ) in treatment of influenza Methods Totally 123 influenza patients with the syndrome of Exterior - Cold and Interior - Heat in traditional Chinese medicine ( TCM ) were randomly divided as TCM group receiving QRPE and control group receiving antiviral drug. Results Compared with the antiviral drug, GQPD was better in antipyretic effect and improvement of influenza symptom scores, being better in effects for disease, TCM syndrome, and cardinal symptoms of influenza. And it showed a tendency to inhibit the immune - inflammatory injury. Conclusion The GQPD is effective and safe in treatment of influenza with TCM syndrome of Exterior - Cold and Interior - Heat.

  12. 体育课程与教学的理论和实践--北京师范大学贾齐教授访谈录%Theory and Practice of Physical Education Curriculum and Teaching---Interview with Professor Jia Qi,from College of Beijing Normal University

    Institute of Scientific and Technical Information of China (English)

    王涛

    2014-01-01

    As Professor Jia Qi said ,physical curriculum and teaching reform in recent decades has deviated from the essential prob-lems .It has not guided the practice effectively ,nor solved the practical problems .Physical curriculum and teaching should extract the essence of pedagogy .The aims of physical education are not to enable students achieve sports standards ,but to cultivate them with sports culture by learning some sports skills ,in order that they can understand the world better .As a part of teaching content , physical education has no difference with other subjects .Physical education has a character to build the students'"mind"by their "body".In physical education ,teachers have to take the students'physique into consideration and treat them individually .Thus , physical education can actually be geared to the needs of all the students .%贾齐教授认为,近十几年的体育课程与教学改革没有抓住问题的实质,堆积了一些漂亮词汇,既不能指导教学实践,也不能有效诠释教学中发生的实际问题;体育课程与教学论要从教育学里面提取精华,体育教学不是要学生达到某种身体运动能力的标准,而是让学生通过动作技术学习,在运动文化传承中陶冶,掌握认识世界的方法;作为教育内容的体育,与其他学科没有本质上的区别,体育的特殊性在于通过学生的“体”育学生的“心”;具体的体育教学过程中充分尊重学生的身体能力,区别对待,真正做到面向全体学生。

  13. 内蒙古扎赉特旗中二叠统岩石地层、生物地层特征及沉积环境分析%THE MIDDLE PERMIAN LITHOSTRATIGRAPHY,BIOSTRATIGRAPHY AND SEDIMENTARY ENVIRONMENTS OF THE JLAID QI,INNER MONGOLIA

    Institute of Scientific and Technical Information of China (English)

    王俊涛; 张永生; 宋天锐; 牛绍武; 曹洁; 田树刚

    2011-01-01

    Survey and systematic sampling were conducted for the Sijiashan and Liutiaogou formations at the Tabenmaodu and Chaganculu section in Jlaid Qi,Inner Mongolia.On the basis of paleontological data,three biostratigraphic zones can be recognized: namely the Monodiexodina-Parafusulina and Codonofusiella-Pseudodoliolina fusulinid assemblages and Waagenophyllum-Wentzelella coral assemblage.The age of the Sijiashan and Liutiaogou formations is is considered to be the Xiangboan Stage to the Lengwuan Stage of the Middle Permian.On the basis of lithostratigraphic features,beds 1~6 at the Tabenmaodu section and beds 1~11 at the Chaganculu section are considered to be the Sijiashan Formation,whereas beds 7~15 at the Tabenmaodu section and beds 12~20 at the Chaganculu section represent the Liutiaogou Formation.According to the analysis of the sedimentary facies in this area,four sedimentary facies and five microfacies are recognized.The middle Permain in this area is dominated by carbonate platformfacies,and a complete carbonate platform depositional cycle consisting of different facies can be recognized.%对扎赉特旗地区塔本毛都和查干楚鲁一带出露的四甲山组、柳条沟组进行了实测和系统采样。根据生物化石组合的特征将其划分为3个生物组合带,即Monodiexodina-Parafusulina,Codonofusiella-Pseudodoliolina组合带,Waagenophyllum-Wentzelella珊瑚组合带。它们产于中二叠统祥播阶至冷坞阶的地层。结合岩性特征及层位对比,塔本毛都剖面的1~6层、7~15层与查干楚鲁剖面1~11层及12~20层分别划归为四甲山组与柳条沟组。沉积相分析表明,剖面可识别出4种沉积相和5种沉积微相。沉积环境为稳定的碳酸盐台地环境,不同沉积相组成一个完整的碳酸盐台地的发育旋回。

  14. Clinical Therapeutic Effect of Traditional Chinese Medicine Therapy on Treating Liver Qi Stagnation and Blood Stasis Patients with Melasma%中医药内外合治肝郁血滞型黄褐斑的临床疗效观察

    Institute of Scientific and Technical Information of China (English)

    田凤艳; 姚春海; 赵一丁; 佘远遥; 迟慧彦; 黄尧洲

    2012-01-01

    目的 观察中药内服、外用及耳穴压豆治疗肝郁血滞型黄褐斑的临床疗效.方法 中医辨证分型为肝郁血滞型的黄褐斑患者,采用随机数字表进行分组,结果完成84例.治疗组46例,中药消斑1号方口服及中药祛斑膜1号方外用配合耳穴压豆治疗;对照组38例,维生素C片和维生素E胶丸口服,0.1%维A酸乳膏外用治疗,治疗12周后进行疗效判定.结果 治疗组有效率为80.43%;对照组有效率为63.16%,2组疗效对比差异有统计学意义(P<0.05).结论 中医药内外合治肝郁血滞型黄褐斑疗效好,安全性高.%Objective To observe the clinical therapeutic effects of traditional Chinese medicine therapy on treating melasma. Methods 84 Patients with raelasma of syndrome of liver Qi stagnation and blood stasis were randomly divided into two groups. 46 patients in the experimental group were treated with the Xiaoban 1 Hao Fang orally and Quban Mo1 Hao Fang externally, and they were treated with the ear pressure beans at the same time. 38 patients in the control group took tablet of vitamin C and soft capsule of vitamin E orally, and they were treated with 0.1 dimensional A emulsifiable paste externally at the same time. Efficacy was evaluated at the baseline and at the end of 12 week's treatment. Results The total effective rate was 80.43% in the experimental group and 63.16% in the control group, respectively. There was a statistically significant difference between these two groups (Ρ<0.05). Conclusion Treatment of melasma by using internal and external Chinese medicine is effective and safe.

  15. 传统中成药治疗气滞血瘀型急性软组织损伤疗效观察%Observation of therapeutic effect of traditional Chinese medicine in treatment of Qi stagnation blood stasis-type acute soft tissue injury

    Institute of Scientific and Technical Information of China (English)

    梁高峰; 乔景泉; 张向阳; 陆琴

    2014-01-01

    Objective:To evaluate the effectiveness and safety of traditional Chinese medicine in treatment of Qi stagnation and blood stasis-type acute soft tissue injury. Methods:82 patients with acute soft tissue injury were randomly divided into treatment group (42 patients) and control group (40 patients). Based on the routine nursing care, the patients in treatment group were given Dahuoluo capsules while those in control group were treated with Xuefu Zhuyu tablets. The treatment of both groups continued for 7days, and then patients'clinical symptoms and physical signs were observed. Results: After the treatment, the scores of pain, swelling and ecchy-mosis of treatment group were lower than those of control group, and the differences had the statistical significance (P<0. 05). Conclu-sions: Traditional Chinese Medicine is effective and safe for the treatment of acute soft tissue injury, and it is worthy of clinical use.%目的:评价传统中药治疗气滞血瘀型急性软组织损伤的疗效及安全性。方法:按入院顺序,将82例气滞血瘀型急性软组织损伤患者随机分为治疗组42例和对照组40例,按损伤程度给予常规护理的基础上分别给予大活络胶囊和血府逐瘀片治疗,7d 后观察患者治疗前、后的临床症状、体征变化情况。结果:治疗后患者的疼痛、肿胀、瘀斑积分等明显下降,治疗组明显优于对照组,总疗效对比有统计学意义(P<0.05)。结论:中医治疗活动期风湿性关节炎疗效明显、安全,值得临床推广使用。

  16. Metallogenic Prognosis and Evaluation of Non-ferrous Metal Deposits Based on GIS and Weights of Evidence Modeling in Keshiketeng Qi of Inner Mongolia%基于GIS和证据权模型的克什克腾旗有色金属成矿预测与评价

    Institute of Scientific and Technical Information of China (English)

    吕鹏; 朱鹏飞; 毕志伟; 陈建平

    2011-01-01

    以地质、地球物理勘探、地球化学勘探、遥感等手段获取的多源数据,经过发现、提取、转换和关联,并利用信息综合技术建立区域综合信息矿产预测模型,进行矿产资源定量评价,是当前矿产资源勘查领域信息找矿的重要途径。本文在对内蒙古赤峰市克什克腾旗地质背景与成矿规律进行研究的基础上,利用GIS技术进行区域成矿专题信息分析与提取,建立评价证据指标模型,使用证据权重法对该区有色金属进行了成矿预测,实践证明利用GIS对研究区开展多源地学信息综合管理,并使用证据权法对区域控矿因素进行统计计算,可以实现综合致矿信息的集成,是区域成矿预测与评价的重要技术和方法手段,同时指出研究区具有进一步找矿的潜力。%Recently,an important approach for mineral resources prospecting and exploration has emerged.It includes obtaining multi-source data by methods of geological,geophysics,geochemistry,and remote sensing;discovery,extraction,conversion and correlation of the multi-source data;and development of a metallogenic prediction model integrated with comprehensive information techniques.Taking the Keshenketeng Qi area in Inner Mongolia as an example,based on its geological setting and metallogenic regularities,this paper analyzes and extracts the comprehensive metallogenic information by GIS technique,and develops a weighted evidence model.Then we perform metallogenic prognosis in the study area.The practice proves its metallogenic significance as an important technique and method.Meanwhile we point out a prospecting potential in the investigated area.

  17. Effect of Reinforcing Kidney Replenishing qi and Promoting Blood Circulation Recipe on the Expression of IGF-1, IGFBP-1 and IGFBP-3 in liver of the Fetal Rat with FGR%补肾益气活血方对胎儿生长受限胎鼠IGF-1、IGFBP-1及IGFBP-3表达的影响

    Institute of Scientific and Technical Information of China (English)

    王琪; 熊丽萍; 陶秀良

    2011-01-01

    Objective To investigate the effect of Bushen Yiqi Huoxue (Reinforcing Kidney Replenishing qi and Promoting Blood Circulation) Decoction on the expression of IGF - 1, IGFBP - 1 and IGFBP - 3 proteins in fetal liver of Fetal growth restriction ( FGR) rat. Methods The smoke inhalation rat model was created. Thirty two pregnant Sprague - Dawley rats were randomly dividedly into four groups: control group, FGR group, group of FGR treated with Bushen Yiqi Huoxue Decoction (Chinese medicine group), group of FGR treated with arginine ( arginine group). The expression of IGF - 1, IGFBP - 1 and IGFBP - 3 proteins in fetal liver were analyzed by immunohistochemis-try. Result Compared with FGR group, the expression of IGF - 1 and IGFBP -3 in fetal liver of Chinese medicine group increased significantly (P 0. 05). Conclusion The effect of Bushen Yiqi Huoxue Decoction on preventing and treating FGR may be attributed to regulating the expression of IGF - 1, IGFBP -1 and IGFBP -3.%目的 观察补肾益气活血方对胎儿生长受限胎鼠肝脏IGF-1、IGFBP-1、IGFBP-3表达的影响,探讨补肾益气活血方治疗FGR的作用机制.方法 采用被动吸烟法建立SD大鼠FGR模型,分为正常组、FGR组、补肾益气活血方治疗组(中药组)、精氨酸治疗组(精氨酸组).采用免疫组织化学方法检测胎鼠肝脏IGF-1、IGFBP-1、IGFBP-3的表达.结果 与FGR组比较,中药组胎鼠肝脏IGF-1、IGFBP-3的表达均明显升高(P<0.05),而IGFBP-1的表达明显降低(P<0.05),并且IGF-1的表达强度高于精氨酸组(P<0.05),各项指标与正常组比较差异无统计学意义(P>0.05).结论 补肾益气活血方可能通过调节IGF-Ⅰ、IGFBP-1、IGFBP-3的表达,从而促进胎儿在宫内的生长发育.

  18. Effects of Shenqi Bufei Tang Decoction on the Expression of HDAC2 and NF-κB p65 in Airway Smooth Muscle Tissues of COPD Rats with Lung-Qi Deficiency Syndrome%参芪补肺汤对COP D肺气虚证大鼠气道平滑肌HDAC2与NF-κB p65表达的影响∗

    Institute of Scientific and Technical Information of China (English)

    吴桂英; 张葵; 闫萍; 张湘燕; 罗莎; 沈力立; 杨柱

    2016-01-01

    Objective To examine the effects of Shenqi Bufei Tang decoction on the expression of histone deacetylase-2 ( HDAC2) and nuclear factor-κB p65 ( NF-κB p65) in the airway smooth muscle tissues of COPD rats with lung-qi deficiency syndrome. Methods A total of 40 male rats were randomly divided into normal control group,model control group,Shenqi Bufei Tang decoction group,and aminophylline group.The COPD rat model with lung-qi deficiency syndrome was established by intra-tracheal instillation of lipopolysaccharide (LPS) and passive smoking for 28 days.Pathological changes of lung tissues were ob-served under the light microscope and the thickness of the small airway wall and airway smooth muscle ( ASM) layer analyzed by the image analysis.Immunohistochemistry,real-time PCR and Western blotting were used to detect the expressions of NF-κB p65 and HDAC2 in ASM. Results The thickness of the airway wall and ASM,and the expression levels of NF-κB p65 mRNA and protein were significantly increased in the model control group when compared with those in the normal control group ( P0.05). Conclu-sion Shenqi Bufei Tang decoction can inhibit the proliferation of ASM in COPD rats with lung-qi deficiency syndrome,which may be associated with the increased expression of HDAC2 and decreased expression of NF-κB p65.%目的:观察参芪补肺汤对慢性阻塞性肺疾病(COPD)肺气虚证大鼠支气管平滑肌(ASM)增殖中组蛋白去乙酰化酶-2( HDAC2)和核因子κB( NF-κB) p65表达的影响。方法将40只SD雄性大鼠随机分为正常对照组、模型对照组、参芪补肺汤组、氨茶碱组,每组各10只。采用气管内滴注脂多糖加烟熏28 d的方法建立COPD肺气虚证模型。光镜下观察肺组织病理形态学变化,图像分析法测量小气道管壁和ASM厚度,采用免疫组化、实时荧光定量PCR和Wester blot方法检测大鼠ASM中HDAC2和NF-κB p65表达。结果与正常对照组比较,模型对照组大

  19. Effect of Reinforcing Kidney Replenishing Qi and Promoting Blood Circulation Recipe on the Expression of IGF-Ⅰ and IGFBP-3 in Brain of the Fetal Rat with FGR%补肾益气活血方对胎儿生长受限胎鼠脑胰岛素样生长因子-Ⅰ与胰岛素样生长因子结合蛋白-3表达的影响

    Institute of Scientific and Technical Information of China (English)

    王琪; 熊丽萍; 屠庆年

    2011-01-01

    Objective To investigate the effect and mechanism of reinforcing kidney, replenishing qi and promoting blood circulation recipe on the protein expression of IGF- Ⅰ and IGFBP-3 in the brains of rat fetal growth restriction ( FGR ). Methods The FGR model was created by passive smoking in SD rats . Thirty-two pregnant SD rats were randomly divided into four groups: control group, FGR group, FGR rats treated with reinforcing kidney, replenishing qi and promoting blood circulation recipe ( Chinese medicine group ), FGR rats treated with L-arginine ( L-arginine group ). The protein expression of IGF-Ⅰ and IGFBP-3 in the fetal brain was analyzed by immunohistochemistry. Results Compared with the FGR model controls [ ( 0. 148 3±0. 015 6 ) and ( 0. 168 9±0.021 4 ) ], the expression of IGF-Ⅰ and IGFBP-3 in fetal brains of Chinese medicine treated group [ ( 0. 191 3 ± 0.017 8) and(0. 187 5±0.023 3 )] increased significantly( P<0.05 ); in addition, the expression of IGF-Ⅰ was higher than that of L-arginine treated group [ ( 0. 193 3±0.020 3 ) ] as well ( P<0.05 ). The difference between the Chinese medicine treated group and the model control one was insignificant ( P>0.05 ). Conclusion The recipe of reinforcing kidney, replenishing qi and promoting blood circulation recipe promotes fetal growth in uterus by regulating the expression of IGF-Ⅰ and IGFBP-3.%目的 观察补肾益气活血方对胎儿生长受限(fetal growth restriction,FGR)胎鼠脑胰岛素样生长因子Ⅰ(insulin-like growth factors Ⅰ,IGF-Ⅰ)、胰岛素样生长因子结合蛋白-3(IGF-binding proteins,IGFBP-3)表达的影响,探讨补肾益气活血方治疗FGR的作用机制.方法 采用被动吸烟法建立SD大鼠FGR模型,分为正常组、FGR组、补肾益气活血方治疗组(中药组)、精氨酸治疗组(精氨酸组).采用免疫组织化学方法 检测胎鼠脑IGF-Ⅰ、IGFBP-3的表达.结果 与FGR组[IGF-Ⅰ、IGFBP-3吸度度值分别为(0.148 3±0.015 6)(0.168 9

  20. Article by LTG Qi Jianguo on International Security Affairs

    Science.gov (United States)

    2013-04-01

    parLisanship, objecliviLy, and empiricism Lhal is the hallmark of CNA research. Our program is built upon a foundation of analytic products and hosted... psychological control.” This is a greater, more long-term danger. Second is to be alert 9 to and guard against Japanese political rightism

  1. Long Term Effect of the Treatment Method of Strengthening Vital Qi, Transforming Phlegm and Clearing Heat for 46 Cases of Bronchiectasis%扶正化痰清热法治疗支气管扩张症46例远期疗效观察

    Institute of Scientific and Technical Information of China (English)

    黄海茵; 彭晓敏; 宋花玲; 吴银根; 杨佩兰; 汤杰; 郎莹莹; 张谊; 宋文宝; 姚亮; 王振伟; 潘夏萍

    2012-01-01

    目的 观察扶正化痰清热法对支气管扩张稳定期(支扩)的远期疗效.方法 将来自3个中心的100例支扩患者随机分为对照组和中药组各50例,对照组予西医常规治疗(主要为胸部体位引流法,若遇急性加重可短期应用抗生素),中药组予西医常规治疗加中药支扩稳定方辨证加减.观察两组患者治疗前及治疗开始1年后急性加重次数、肺功能[包括用力肺活量(FVC)、第一秒用力呼气容积(FEV1)],并根据圣乔治问卷(SGRQ)进行生活质量评分.结果 治疗后中药组患者急性加重次数较前明显减少(P<0.01),而对照组患者急性加重次数无明显变化(P>0.05),两组急性加重次数变化率差异有统计学意义(P<0.01).治疗后,中药组SGRQ症状、活动、心理及总分较治疗前均明显减少(P<0.05或P<0.01),而对照组治疗后各项评分改善均不明显(P>0.05);治疗后中药组与对照组比较,除症状评分外,其他3项评分差异均有统计学意义(P<0.01);治疗前后评分差值比较,两组活动评分、症状、心理及总分差异均有统计学意义(P<0.05或P<0.01).治疗后,对照组FVC、FVC%、FEV1、FEV1%均明显降低(P<0.05),中药组FVC%下降(P<0.05).中药组治疗后FEV1值趋于稳定,与对照组比较差异有统计学意义(P<0.05),中药组治疗前后FEV1、FEV1%变化率与对照组比较差异有统计学意义(P<0.01).结论 根据扶正化痰清热法辨证施治,能减少支扩患者年急性加重次数,提高生活质量,减缓肺功能FEV1的下降,提高远期疗效,且安全性良好.%Objective To observe the long term effect of strengthening vital qi, transforming phlegm and clearing heat for stable bronchiectasis. Methods One hundred cases of stable bronchiectasis from three clinical centers were randomized into the control group and Chinese medication group, with 50 in each. The control group was treated with conventional western medication

  2. Study on compound donkey-hide gelatin syrup in reducing adverse reactions of Qi-blood deficiency patients caused by clozapine%复方阿胶浆对气血两虚型精神病患者氯氮平治疗后不良反应的影响

    Institute of Scientific and Technical Information of China (English)

    杨俊伟; 罗诚; 张超; 王延军; 王忠; 任继平

    2013-01-01

    Objective To investigate the compound donkey-hide gelatin syrup in reducing adverse reactions of qi-blood weakness patients caused by clozapine.Methods 132 patients from Psychiatric Hospital of Yunnan Province between January 2010 and June 2010 were randomly divided into a treatment group and a control group.Both groups were taken clozapine orally.On this basis,the treatment group was taken compound donkey-hide gelatin syrup and the control group was taken placebo syrup.After 8 weeks treatment for both groups,the PANSS,TESS,physical examination and experiment examination were observed to evaluate the clinical efficacy and safety.Results ① the total curative effect:the treatment group was 73.53%,the control group was 65.63%,showing statistical difference (x2=2.543,P<0.05).② PANSS scores changes before and after the treatment:PANSS score at 2,4,6,8 weeks after the treatment of both groups were [(72.51 ±27.55),(60.54±24.03),(53.12± 15.27),(48.15± 11.88) in treatment group respectively,and (70.71 ±23.90),(58.89± 18.95),(53.06± 14.38),(48.98 ± 9.78) in the control group,respectively],both showing significant difference than the same group before the treatment [(103.99±39.12) in the treatment group,(99.78±34.35) in the control group] (P<0.05).But there was no statistical significance between two groups (F=2.413,P>0.05).③ adverse reactions:during the treatment liver function,blood cell analysis,dystonia,Parkinson's obstacle,akathisia,abnormal gastrointestinal reaction,heart rate,heart rate variability and blood pressure in the treatment group was significantly lower than the control group (x2=4.562,P<0.05).Conclusion Compound donkey-hide gelatin syrup can effectively relieve adverse reactions in qi-blood weak psychosis patients after clozapine treatment and improve their drug tolerance.%目的 探讨复方阿胶浆对气血两虚型精神病患者氯氮平治疗后不良反应的疗效观察.方法 收集2010年1月至2011年6月云南

  3. 补肾健脾益气法对酒精性骨质疏松大鼠骨密度(BMD)、骨矿含量(BMC)影响的研究%Influence of the Method of Tonifying Kidney, Strengthening Spleen and Supporting Qi on Bone Mineral Density(BMD) and Bone Mineral Content(BMC)with Alcoholic Osteoporosis(AOP) in Rats

    Institute of Scientific and Technical Information of China (English)

    任树军; 邢国利; 姜益常; 葛明富; 毕旭伟

    2013-01-01

    Objective: To observe the influence of the method of tonifying kidney, strengthening spleen and supporting Qi on bone mineral density (BMD) and bone mineral content (BMD) with Alcoholic osteoporosis (AOP) in rats, and to investigate the mechanism of herbs for strengthening kidney and spleen on AOP. Method: 40 adult male SD rats of pathogen - free were randomly divided into four groups on average: model group, western medicine control group, Chinese medicine intervention group and normal control group. The animal model of AOP was induced by irrigation stomach with the Red Start ( Hongxing) Erguotou ( rats in normal control group received saline) , simultaneously, saline, Calcium Carbonate alpha D3, JianGuLing capsule and saline were given to four groups, respectively. Sixteen weeks later, BMD and BMC of thighbone were measured by dual energy X - ray absorptiometry. Results: BMD and BMC in model group were remarkablely decreased compared with normal control group, the difference was significant(P <0. 01) , which suggested that rats receiving high concentrations of liguor for 16 weeks really resulted in decrease of BMD and BMC. Furthermore, BMD and BMC in Chinese medicine intervention group(P < 0.01) and western medicine control group (P < 0.05) were remarkablely increased compared with model group. In addition, BMD and BMC in Chinese medicine intervention group were higher than those in Western medicine control group(P < 0.05) , suggesting that Chinese medicine intervention group was superior to western medicine control group. Conclusion: Rats with AOP possess bone metabolism disorder, bone formation decreasing, bone loss reducing and finally induced osteoporosis. The method of tonifying kidney, strengthening spleen and supporting Qi can enhance BMD and BMC, and inhibit loss of bone mineral in rats with AOP, thereby it can effectively improve bone metabolism of rats with AOP.%目的:观察补肾健脾益气法对酒精性骨质疏松(AOP)大鼠骨密度影

  4. Effect of Recipe of Supplementing Qi and Activating Blood (RSA) on NO3-、ONOO-、MDA、GLU、AMY in Faeces of High Fat Diet Rats%补气活血法对高脂饮食大鼠粪便NO-3 、ONOO- 、MDA、GLU、AMY的影响

    Institute of Scientific and Technical Information of China (English)

    马月梅; 刘晓秋; 张永斌

    2011-01-01

    Objective To investigate the effect of high fat diet on NO3-、 ONOO - ,MDA,glucose,amylase activity. PNA,PSA binding rates af amylase, amylase isoenzyme profile in rat faeces and the effect of recipe of supplementing Qi and activating blood ( RSA )Methods Male rats were randomly divided into four groups: normal group( feeding ordinary diet) ; model group( feeding high fat diet) ;RSA Ⅰ ( feeding RSAI ( S: A =2: 1) by gastrogavage) ; RSA 2 ( feeding RSA2 ( S: A = 1 : 2) by gastrogavage) . N03- , ONOO- , MDA , glucose and amylase activity in rat faeces were determined by colorimetric method. N -glycan patterns of amylase were determined with lectin ( PSA and PNA) affinity precipitation method, and faeces amylase isoenzyme profile was separated by electrophoresis on polyacrylamide gels electrophoresis ( PAGE). Results High fat diet rats showed the symptoms of polyuria, polydipsia, polyphagia and weight loss. These abnormal signs were improved after treatment with RSA. In high fat diet rats, amylase activity, N03 - , P - Amy.S - Amy in faeces were decreased, while PSA, PNA binding rates of amylase, glucose, ONOO - in faeces were increased. After treatment with RSA, all of these indicators were improved. There was difference between RSA1 action and RSA 2 action. Conclusion Supplementing Qi and activating blood method can improve N - glycan deficiency in faeces amylase and up - regulate faeces amylase activity , and increase N03- , also decrease glucose, ONOO- in faeces, thus can regulate the digestion/absorption and glucose metabolism, can reduce oxygen free radicalinduced intestinal damage. This study also showed the different impacts of two different RSA.%目的 研究高脂饮食对大鼠粪便NO3-、ONOO-、MDA、GLU、AMY活性、AMY PSA、PNA结合率、AMY谱的影响,同时研究补气活血中药的作用.方法 雄性SD大鼠随机分为正常组,喂饲普通饲料;模型组,喂饲高脂饲料;补气活血1组(RSA 1),2∶ 1补气

  5. Effects of Chinese herbal medicines for regulating liver qi on expression of 5-hydroxytryptamine 3B receptor in hypothalamic tissues of rats with anger emotion%调肝方药对愤怒和郁怒情绪模型大鼠下丘脑5-羟色胺3B受体表达的影响

    Institute of Scientific and Technical Information of China (English)

    葛庆芳; 张惠云

    2011-01-01

    Objective: To explore the central mechanisms of anger emotion and the effects of Chinese herbal medicines for regulating liver qi on the anger emotion and the expression level of 5-hydroxytryptamine 3B receptor (5-HT3BR) in rat hypothalamus.Methods: Rat models of anger-in or anger-out emotions were prepared by the methods of resident intruder paradigm. There were five groups in this study: control, anger-in model, Jingqianshu Granule-treated anger-in, anger-out model and Jingqianping Granule-treated anger-out groups. The treatment groups were orally given Jingqianshu granules and Jingqianping granules respectively, and the model groups and the normal control group were given sterile water. Open-field test and sucrose preference test were used to evaluate behavioristics of the rats. Semi-quantitative reverse transcription-polymerase chain reaction and Western blot methods were used to detect the expression levels of 5-HT3BR mRNA and protein in the rat hypothalamus. Results; The expression of 5-HT3BR in hypothalamus of anger-in model rats increased obviously (P<0.01) and that of anger-out model rats decreased obviously (P<0.01) compared with the normal control group. Compared with the model group, the expressions of 5-HT3BR in the treatment groups were significantly improved (P<0.01) after treatment, and recovered to normal level.Conclusion: The anger-in stimulation obviously increases hypothalamic 5-HT3BR expression and the anger-out emotion can obviously reduce its expression. Chinese herbal medicines for regulating liver qi may treat anger emotion in rats by improving the hypothalamic 5-HT3BR protein and gene expression levels.%目的:观察大鼠下丘脑5-羟色胺3B受体(5-hydroxytryptamine 3B receptor,5-HT3BR)表达的变化,探讨大鼠下丘脑5-HT3BR在愤怒和郁怒反应情绪发生机制中的作用,研究中药复方经前平颗粒和经前舒颗粒改善愤怒和郁怒情绪的中枢作用靶点.方法:采用居住入侵结合社会隔离的方法

  6. 黄芪注射液治疗糖尿病肾病随机对照试验报告质量评价%Quality Evaluation of the Report for Randomized Controlled Trials of HuangQi Injection in Treating Diabetic Nephropathy

    Institute of Scientific and Technical Information of China (English)

    任芳; 徐厚谦

    2013-01-01

    Objective:To evaluate the quality of randomized controlled trial (RCT) report about HuangQi in-jection in treating diabetic nephropathy (DN) with Jadad scales≥three points by CONSORT standard. Method:All the papers of randomized and semi-randomized controlled clinical trials about HuangQi injection in treating DN were searched before January, 2013, quality of RCT report with Jadad scales≥three points was assessed comprehen-sively by CONSORT statement and some TCM indexes. Data extraction and quality evaluation of literature method-ology were performed by two judges independently. If there was the dispute, it should be solved through discussion or main investigators. Result:Altogether 480 articles were detected, and only 16 pieces met the standard. Among 16 included articles, there were 16 articles with diagnostic criteria, which accounted for 100.0%;14 ones with detailed medication plan and the course of the treatment, which reached 87.5%;11 ones with right demonstration of random-ized distribution method, and 68.75%;15 with the presentation of statistical method, and 93.75%;12 pieces with the description of the included objects and 75.0%; 14 ones describing baseline information in different groups and 87.5%;five pieces referring to the number of the cases quit or dropped, and 31.25%;nine articles talking about ad-verse reactions and 56.25%;only one piece discussing TCM patterns and 6.25%. There was no article mentioning the estimate of samples contents, the hide and implementation of distribution plan, flowchart of the objects, inten-tion-to-treat analysis and observation of endpoint indexes. Conclusion:Since methodology and results for most of the RCT are not reported in detail, we suggest that RCT should be reported according to CONSORT standard to improve the quality and the authenticity of RCT.%目的:应用CONSORT标准评价Jadad评分≥3分的有关黄芪注射液治疗糖尿病肾病的RCT报告质量。方法:按照Cochrane协作网制

  7. 益气滋肾合剂对牙周炎大鼠外周血TNF-α、IL-1β含量及牙槽骨微观形态的影响%Effect of Tonifying Qi Nourishing Kidney Mixture on peripheral levels of TNF-α and IL-1 β and morphological changes of alveolar bone in periodontitis rats

    Institute of Scientific and Technical Information of China (English)

    杨霞; 向学熔; 李丛华; 黄孝庆

    2011-01-01

    Objectives To determine the effect of Tonifying Qi Nourishing Kidney Mixture on the level of tumor necrosis factor-α(TNF-α)and cytokine interleukin-1β (IL-1 β ) in the peripheral blood and on morphological changes of alveolar bone during experimental periodontitis. Methods Eighty 5-months-old Wistar rats were divided into 5 groups at random. The rats of Group N was killed at the beginning of the experiment and used as the normal control. And the animals of Group A, B1, B2 and B3 were inflicted to be periodontitis models by ligating dental cervix with steel wire, high-glucose feeding and topical hormone treatemnt. The rats in group A were killed at the end of periodontitis establishment to assess the features of the model. The rats fo Group B1, B2 and B3 received an intragastrical injection of the mixture at 20, 10 and 5 g/(kg · d) respectively for 12 weeks and then were killed after general evaluation and blood sampling. The levels of TNF-α and IL-1 β in the peripheral blood were measured with enzyme-linked immunosorbent assay. Morphological changes of alveolar bone was observed by microcomputed tomography (micro-CT). Results The levels of TNF-α and IL-1β in treated group B1 (4.909 ±0.505 and 0.318 ±0.086) and group B2(4.085 ±0.374 and 0. 266 ±0. 062) were significantly lower than those in the control group A (4.909 ±0.505 and 0. 318 ±0.086, P < 0. 01 ). At the same time, trabecular number and trabecular separateion in the experimental group B1 ( 1.95 ± 0.34 and 362.3 ± 62.7) and group B2 ( 1.88 ± 0. 39 and 396.2 ± 58.2 ) were significantly better than those in the control group A ( 1.24 ± 0. 22 and 789.3 ± 157. 0, P < 0.01 ). Conclusion Tonifying Qi Nourishing Kidney Mixture reduces the levels of TNF-α and IL-1β in the peripheral blood, and enhances the density of alveolar bone, thus exerting therapeutic effect on periodontitis.%目的 观察益气滋肾合剂对牙周炎大鼠外周血TNF-α和IL-1β水平的影响,探讨其

  8. 益气解毒法不同组方对鼻咽癌CNE2Z细胞迁徙运动潜能及相关基因表达活性的影响*%Effects of different formulae composed from the therapeutic principle of Qi-boosting toxin-resolving on migrating potentiality and associated gene expressive activities of CNE2Z NPC cells

    Institute of Scientific and Technical Information of China (English)

    2013-01-01

    Objective To investigate the effect of different formulae composed from the therapeutic principle of Qi-boosting toxin-resolving on the migrating potentiality and associated gene expressive activities of nasopharyngeal carcinoma (NPC) cell line CNE2Z cells. Methods Firstly, different formulae derived from the same therapeutic principle of Qi-boosting toxin-resolving were composed only with their dosages changed but not with their composing kinds of herbs, i.e. the original formula (OF) and the modified one (MF). Herbal medicines-containing plasma (HMCP) were prepared routinely from rats by feeding method with these two formulae. Then, HMCP of these two formulae were cultured with CNE2Z cells in different concentrations respectively to detect their effects on migrating potentiality of these cells by scratching test. Immunohistochemical SABC assay was used to determine the expressive levels of nm23-H1 and c-myc in different groups of cells, and RT-PCR techniques were taken to confirm the transcribing activities of nm23-H1 mRNA and c-myc mRNA. Their interaction was evaluated by careful analysis on these data at last. Results TIt was shown from the experiment of scratching that the motility ability of targeting cells was significantly inhibited by the effect of OF and promoted by the effect of MF, inhibit potentiality of motility of CNE2, modified QBTRF promote potentiality of motility of CNE2. However, their effects on the expression of nm23-H1 and c-myc genes were rather complicated. OF showed no obvious effect on the expression of c-myc but giving rise a promoting effect on that of nm23-H1 protein (P0.05). In contraction, MF produced a promoting effect on the expressive activity of c-myc mRNA at higher dosage, significantly higher than that of controlling group(P0.05). Conclusion The original Qi-Boosting Toxin-Resolving formula gives rise an inhibitory effect on migrating potentiality of CNE2Z cells, while the modified Qi-Boosting Toxin-Resolving formula induces a

  9. Development of China's Thoughts of Constitutional Government and the Revolution of 1911——Investigation on the Objects of Qing Government,LIANG Qi-chao and SUN Yat-sen%中国宪政理念的发展与辛亥革命——以清政府、梁启超和孙中山为考察对象

    Institute of Scientific and Technical Information of China (English)

    梁文生

    2011-01-01

    清末民初,宪政改革是主流共识。清政府把宪政视为工具,维护其君主专制。梁启超的宪政理念是支持民权、反对专制,但是他与现实妥协,提倡"开明专制"。孙中山的宪政理念以民为本,主张共和宪制,更符合宪政的内在价值。辛亥革命的成功与宪政理念的发展密切相关。%In the late of Qing dynasty and the early of Republic of China,the reform of constitutional government is social consensus.Qing government regarded the constitutional government as a tool to maintain the autocratic monarchy.LIANG Qi-chao's thoughts of constitutional government supported the civil rights and were against the autocratic monarchy,but he compromised of the reality to advocate the enlightened autocratic.SUN Yat-sen's thoughts of constitutional government supported the civil rights and advocated a constitutional republic,which conformed to the inner values of constitutional government.The success of the revolution of 1911 was relevant of the Development of China's thoughts of constitutional government.

  10. Comparative study of immunosuppression of HuangQi glycoprotein, triptolide, rapamycin and hydrocortisone in vitro%黄芪糖蛋白、雷公藤甲素、雷帕霉素和氢化考的松体外免疫抑制作用的比较研究

    Institute of Scientific and Technical Information of China (English)

    杨向竹; 赵俊云; 崔向青; 胡秀华; 冯前进; 刘亚明

    2011-01-01

    目的:比较黄芪糖蛋白与雷公藤甲素、雷帕霉素、氢化考的松的体外免疫抑制作用.方法:不同浓度黄芪糖蛋白、雷公藤甲素、雷帕霉素、氢化考的松作用于小鼠脾细胞,MTT法测定4种药物对ConA、LPS诱导的淋巴细胞增殖的影响,流式细胞仪测定4种药物对脾细胞培养上清液中细胞因子IFN-γ、IL-6含量的影响.结果:4种药物对体外培养的脾细胞增殖均表现出显著的抑制活性(P<0.05),药效强度依次为雷公藤甲素、雷帕霉素、氢化考的松、黄芪糖蛋白.但黄芪糖蛋白主要表现为对T细胞的抑制作用.黄芪糖蛋白促进淋巴细胞分泌IFN-γ、IL-6,而其它3种药物却抑制IFN-γ、IL-6的分泌(P<0.05).结论:黄芪糖蛋白对于淋巴细胞体外增殖的抑制作用不同于雷公藤甲素、雷帕霉素、氢化考的松,推测其具有独特的作用机制.%Objective: To compare the difference between immunosuppressants of HuangQi glycoprotein(HQGP), Triptolide(Tri), Rapamycin(RAPA) and Hydrocortisone (HC) in vitro. Methods: The effects of different immunosuppressants on the lymphocytes proliferation treated by mitogens were measured with MTT. Having been cultured for 48 hours, supematants were collected and tested for cytokine production by flow cytometry. Results: HQGP could notably inhibit the proliferation of lymphocytes induced by mitogens in dose-dependent fashion, as well as Tri, RAPA and HC. The order of Pharmacodynamic strength is Tri, RAPA, HC and HQGP. After measured the cytokines production in splenic cell supematants, it is observed that production of IFN- γ, IL-6 is increased when lymphocytes are treated by HQGP and that of them is suppressed when treated by Tri, RAPA and HC. Conclusion: The effects of HQGP on T and B cells in vitro are different from those of Tri, RAPA, and HC, so it is speculated that HQGP has unique function mechanism.

  11. Study of the Anti-tumor Effect and Mechanism of Strengthening Healthy Qi and Eliminating Pathogenic Factors on Mice Model with Lewis Lung Cancer%扶正法、祛邪法对Lewis肺癌小鼠的抑瘤作用及机制研究

    Institute of Scientific and Technical Information of China (English)

    齐元富; 张盈盈; 李慧杰; 郑祎; 刘寨东

    2016-01-01

    Objective:To study of the anti-tumor effect and mechanism of strengthening healthy Qi and elimi-nating pathogenic factors on mice model with Lewis lung cancer. Method:The Lewis lung cancer mouse model was established,the mic were divided into different groups and given intervention. The anti-tumor rate of each group was calculated,the expression of BCL-2 in tumor cells was measured with immunohistochem-istry,the expressions of caspase-3 mRNA,surviving mRNA were detected with real-time PCR. Results:Qizhen guben formula and Qinlian zhengji formula all had certain anti-tumor effect,with the anti-rate 18.42% and 29.24% respectively,and there were no significant differences between two groups(P>0.05). When compared to the control group,they all could significantly promote the expression of caspase mRNA and down-regulate the expression of BCL-2 survivin mRNA,but the their effect was not better than cisplatin. Conclusion:Qizhen guben formula and Qinlian zhengji formula did possess anti-tumor effect and this effect of Qinlian Zhengji formual was stronger. Their mechanism of action may be related to promoting the expression of caspase mR-NA and down-regulating the expression of BCL-2 and survivin mRNA.%目的:研究扶正法、祛邪法对Lewis肺癌小鼠的抑瘤作用并探讨其作用机制.方法:建立Lewis肺癌小鼠移植瘤模型,按实验分组干预,计算各组抑瘤率,免疫组化法检测BCL-2表达情况,RT-PCR法检测Caspase-3 mRNA、Survivin mRNA表达情况. 结果:芪贞固本方、芩莲正积方均有不同程度的抑瘤作用,其抑瘤率分别为18.42%、29.24%,两组比较差异无统计学意义(P>0.05);二方均可促进Caspase-3 mRNA的表达,抑制BCL-2、Survivin mRNA 的表达,与对照组比较有显著统计学意义(P<0.05),但均不及DDP组. 结论:芪贞固本方和芩莲正积方确有抗肿瘤作用,芩莲正积方作用略强,其机制可能为促进Caspase-3 mRNA的表达,抑制BCL-2、Survivin mRNA的表达.

  12. 2种慢性间歇性缺氧小鼠模型模拟气阴两虚证临床指征的比较研究%Comparison of Clinical Indications Simulating Deficiency of Both Qi and Yin Syndrome Induced by Two Types of Chronic Intermittent Hypoxia in Mice

    Institute of Scientific and Technical Information of China (English)

    王文萍; 柴程芝; 寇俊萍; 余伯阳

    2011-01-01

    目的:比较钠石灰和低压氧仪2种不同缺氧方式诱导的慢性间歇性缺氧小鼠模型的整体行为变化,为进一步构建气阴两虚证动物模型奠定基础.方法:分别采用氧分压从21%逐渐降至6%,平均下降速度为0.5%/min ~ 1%/min的钠石灰缺氧法和氧分压在短时间内骤降后维持在7% ~8%的低压氧仪缺氧法,考察2种缺氧模式对小鼠体重,摄食量,自发活动以及心率、T波等气阴两虚临床相关指标变化的影响.结果:钠石灰和低压氧仪2种不同的缺氧方式均能够导致小鼠体重下降;摄食量减少;行走格数减少,直立次数增加等自发活动改变;心率加快,T波持续抬高等心电图变化,二者对各项指标的影响呈基本一致的趋势,其结果具有显著相关性.结论:钠石灰和低压氧仪2种缺氧方式诱导的慢性间歇性缺氧小鼠模型均能够模拟形体消瘦,食欲不振,体倦乏力,烦躁,心悸,脉细数等气阴两虚证的主要临床特征.%Objective: To establish foundation for constructing a suitable animal model of deficiency of both Qi and Yin syndrome (DQYS) induced by two types of chronic intermittent hypoxia (soda lime and low-pressureoxygen controller) by comparison the whole behavior in mice. Method: The two modes of oxygen scarcity,including oxygen pressure declining continuously from 21% to 7%-8% with the average speed of 0. 5%/min-l% per minute in airtight wide-mouthed bottle and oxygen pressure falling abruptly within short period and then keeping in the level of 7% -8% ,were adopted respectively to observe the time-course changes in body weight, food intake, locomotive activity and electrocardiogram respectively. The experiments were designed for mimicing clinical features of DQYS. Result; The mice exposed to two different modes of chronic intermittent hypoxia for certain duration showed body weight loss, food intake decline, locomotive activity change of ambulation decrease and rearing increase

  13. 加味生脉散对气虚型鼻咽癌大鼠的放射增敏作用及相关机制%Radiosensitization and Mechanisms of Jiawei Shengmai San on Nasopharyngeal Carcinoma in Rat with Qi Deficient Status

    Institute of Scientific and Technical Information of China (English)

    魏辉; 王启瑞; 刘英; 王志远; 蔡红兵; 孙学刚; 刁建新; 刘远亮; 范钦

    2012-01-01

    目的:探讨加味生脉散对气虚型鼻咽癌大鼠放疗增敏作用及相关机制.方法:SD大鼠于玻璃水缸中游泳,每天10 min,共30 d.同时在大鼠腋部皮下注射二亚硝基哌嗪(DNP),剂量为0.5 mg/只/次,每3d注射1次,共注射30次,于90 d内完成,构建鼻咽癌大鼠模型.实验分为对照组、药物组、放疗组、药物+放疗组,通过测量肿瘤体积及计算抑瘤率,观察药物加味生脉散的放疗增敏作用;荧光定量PCR及Western-blot检测瘤组织多药耐药基因-1(MDR1)基因的表达差异.结果:肿瘤质量,对照组(1230.0±106.8)mg,放疗组为(447.2±121.9) mg,与对照组比较,P<0.05,抑瘤率53.25%;药物加放疗组为(259.9±64.7)mg,与放疗组比较,P<0.05,抑瘤率72.81%;相对表达倍数,药物组为1.21,放疗组为1.85,药物加放疗组为1.34.结论:加味生脉散对鼻咽癌的放疗具有增敏作用,其增敏机制可能与抑制MDR1基因的表达相关.%Objective: To investigate radiosensitization and mechanism of Chinese medicine Jiawei Shengmai San on nasopharyngeal carcinoma. Method; The SD rats swimed in Class tank for 10 minute in 30 days, at the same time, subcutaneous injection of dinitrosopiperazine (DNP) was performed, the dose was 0.5 mg every time, every 3 days the injection was carried out once for 90 days. Then, nasopharyngeal carcinoma models with Qi deficient status was produced. The samples were divided into control group, drug group, radiotherapy group, drug + radiotherapy group. The radiosensitization effect was measured by measuring tumor volume and weight, and multidrug resistance 1 gene (MDR1) expression was detected by quantitative PCR and western-blot. Result; In the control group tumor weight was (1 230. 0 ± 106. 8) mg, in the radiotherapy group being (447. 2 ± 121. 9) mg. Compared with the control group, the ratio of tumor inhibition was 53. 25% , there was a significant difference (P < 0. 05 ). In the drug + radiotherapy group tumor

  14. Dongwei Granule in treatment of chronic gastritis with cold obstruction causing qi stagnation and cold obstruction causing blood stasis:a randomized parallel controlled clinical trial%冬胃颗粒治疗寒凝气滞与寒凝血瘀型慢性胃炎疗效观察

    Institute of Scientific and Technical Information of China (English)

    于丽; 李昊燃; 雷春红; 陈晶; 林一帆; 赵明宏; 陆宇平; 高文艳; 巩阳; 刘杨; 季芳

    2012-01-01

    [Objective]To evaluate the clinical efficacy and safety of Dongwei Granule on chronic gastritis with cold obstruction causing qi stagnation (COCQS) and cold obstruction causing blood stasis(COCBS). [Methods]Eighty-six patients of chronic gastritis with COCQS and COCBS were selected for a randomized parallel controlled trial. The 43 cases in the study group were treated with Dongwei Granule 8g tid for seven days, while another 43 in the control group were given hydrotalcite 0. 5g tid, and then the clinical efficacy and safety were investigated. [Results]Both groups have some curative effect, however, the evaluation of curative effect of Dongwei Granule in abdominal pain,belching,anorexia at day 1,3,7,14 gained an advantage over that of hydrotalcite (P<0. 01). Although the effect of hydrotalcite in water brash was slightly superior to that of Dongwei Granule at day 1 and 3, there was no statistical significance(P=0. 5359,0. 7318),and the latter had better effect than the former at day 7 and day 14(P<0. 01). The evaluation of curative effect of Dongwei Granule in water brash gained an advantage over that of hydrotalcite(P<0. 01) by the analytical method of logistic model duplicate measurement,no obvious side effects were found. [Conclusion]Dongwei Granule could effectively prevent and cure chronic gastritis with COCQS and COCBS and quickly relieve the symptoms.%[目的]观察冬胃颗粒治疗寒凝气滞与寒凝血瘀型慢性胃炎的临床疗效及安全性.[方法]86例寒凝气滞与寒凝血瘀型慢性胃炎患者随机分为2组,试验组(43例)给予冬胃颗粒8 g,3次/d,对照组(43例)给予铝碳酸镁片0.5g,3次/d,2药均于两餐间及睡前服用,疗程为2周,观察各组第1、3、7、14天腹痛腹胀、泛酸、嗳气与纳差症状缓解情况,同时观察其安全性.[结果]2组患者均有一定疗效,但冬胃颗粒治疗后第1、3、7、14天患者腹痛腹胀、嗳气、纳差症状疗效指标的评价均优于铝碳酸镁(P<0.01),

  15. 益气养阴、活血化瘀中药对糖尿病大鼠脂代谢紊乱及蛋白质非酶糖基化的影响%Effect of Chinese herb for benefiting qi, nourishing yin, activating blood circulation and resolving stasis on lipid metabolic disturbance and protein nonenzyme glycosylation in diabetic rats

    Institute of Scientific and Technical Information of China (English)

    戴红

    2005-01-01

    benefiting qi, nourishing yin, activating blood circulation and resolving stasis at the same time of controlling blood glucose.OBJECTIVE: To observe the effect of huaxiaoyin (HXY), the Chinese herb for reinforcing qi, nourishing yin, promoting blood circulation and re solving stasis on blood lipid, collagen content and fluorescence degree of collagen-protein advanced glycation end products(AGEs) in thoracic aorta in diabetic rats.DESIGN: Complete randomized group division and control experiment were designed.SETTING: Traditional Chinese Medicine Department of Diagnostics,Hubei College of Traditional Chinese Medicine MATERIALS: The experiment was performed in Center Experimental Room of Hubei College of Traditional Chinese Medicine from May 2001 to August 2002, in which, 90 Wistar pedigree rats of clean grade were employed.METHODS: ① 12 rats were randomized in normal control. For the rest 78 rats, after 12-hour fasting, streptozotocin (STZ) was intravenously injected from tail at 50 mg/kg for one time. 72 hours later, it was assayed that 16.65 mmoL/L < fasting blood sugar < 33.3 mmol/L indicated successful modeling. Totally 76 rats had been modeled successfully. Diabetic rats were randomized into 5 groups, named model group (n=16), insulin group (n=15), HXY low-dose group (n=15), HXY middle-dose group (n=15) and HXY high-dose group (n=15). ② In normal control group and model group, gastric perfusion was prescribed with normal saline 4 mL. In insulin group, protamine zinc insulin 1-2U was injected subcutaneously. In HXY low, middle and high-dose groups, besides, subcutaneous injection of protamine zinc insulin 1.0-2.0U, HXY was administered [composed of shanyao (Rhizoma Dioscoreae), shengdi (Radix Rehanniae), huafen (Radix Trichosanthis), danshen (Radix Salviae Miltiorrhizae), huangqi (Radix Astragali), zhimu (Rhizoma Anemarrhenae), totally 12 herbs, the content of raw herbs was 2 g/mL] at 0.75, 1.5, 2.0 kg/L, 4 mL for each respectively. Gastric perfusion was

  16. 益气健脾中药对脾气虚大鼠神经肽Y、血管活性肠肽和丝裂原活化蛋白激酶14基因表达的影响%Effect of Yiqi Jianpi Herb on Content of NPY, VIP and Expression of Mapk14 mRNA of Rats with Spleen-qi Deficiency

    Institute of Scientific and Technical Information of China (English)

    段永强; 程卫东; 杜娟; 杨晓轶; 刘靓; 巩子汉; 朱立鸣; 成映霞; 李兰珍

    2014-01-01

    目的:观察脾气虚大鼠血清、小肠神经肽Y (NPY)和血管活性肠肽(VIP)含量,小肠组织丝裂原活化蛋白激酶14(Mapk14)mRNA表达的变化及益气健脾中药的干预效应,以揭示脾气虚证发生的内在机制。方法受试动物随机分为空白组、模型组(7、14、21 d组)、益气健脾组,每组10只。除空白组外,其余各组采用大黄法、力竭法及饥饿法复合法建立脾气虚证大鼠模型,造模同时益气健脾组每日给予四君子汤20 g/kg干预21 d,各组大鼠分时段采用放免法测定小肠、血清NPY和VIP含量,采用实时荧光定量PCR检测小肠组织Mapk14 mRNA表达水平。结果与空白组比较,模型组大鼠血清及小肠组织 NPY 含量降低(P<0.05),VIP 含量升高(P<0.05),小肠组织Mapk14 mRNA相对表达量升高(P<0.05),且以模型21 d组显著;与模型21 d组比较,益气健脾组大鼠血清及小肠组织NPY含量升高(P<0.05),VIP含量降低(P<0.05),小肠组织Mapk14 mRNA相对表达量降低(P<0.05)。结论益气健脾中药具有调节脑肠肽NPY、VIP分泌及抑制小肠组织Mapk14 mRNA异常表达的作用。%Objective To investigate the effect of Yiqi Jianpi herb on content of NPY, VIP and expression of Mapk14 mRNA of rats with spleen-qi deficiency. Methods Rats were randomly divided into normal groups, model group (observed on 7 d, 14 d and 21 d), treatment group of Yiqi Jianpi herb, 10 rats in each group. The spleen-qi deficient model rats were made by rhubarb, exhaustive and hungry method, and treatment group was treated with Sijunzi decoction (20 g/kg) for 21 d, then the content of NPY, VIP in serum and small intestine were evaluated with radioimmunoassay, and expression of Mapk14 mRNA in small intestine tissue was evaluated with real time fluorescent quantitative PCR. Results In model group, content of NPY was much lower than that of normal group (P<0.05), content of VIP and relative expression of Mapk14 mRNA in small intestine

  17. Effects of combined Ginkgo biloba extraction with edaravone on brain cell apoptosis and bcl-2/bax expression in rats with Qi deficiency and blood stasis after cerebral ischemia reperfusion injury%银杏叶提取物联合依达拉奉对气虚血瘀型脑缺血再灌注大鼠细胞凋亡及bcl-2/bax表达的影响

    Institute of Scientific and Technical Information of China (English)

    侯晞; 梁枫; 李爱剑; 王灿; 戴体俊; 桂常青

    2011-01-01

    Objective:To observe the effects of combined extraction of Ginkgo biloba leaves ( EGb ) with edaravone (ED) on brain cell apoptosis and bcl-2/bax expression in rat models with deficiency of Qi and blood stasis after cerebral ischemia reperfusion injury. Methods: Rat models with Qi deficiency and blood stasis were initially developed by starvation,fatigue and intake of high-fat diet, followed by temporary middle cerebral artery occlusion for 2 hours for cerebral ischemic reperfusion injury. After 72-hour therapy of the injury, we observed the effects of single use of EGb and ED as well as combined both agents, respectively, on the brain cell apoptosis and bcl-2/bax expression in the animal models. Results:Simple EGb and ED as well as combined use of the both agents could delay the cell apoptosis, down-regulate the expression of bax but increase bcl-2 except for reduction of the nerve cell injury as compared with the model group( P <0. 01 ). Importantly, the effects appeared prominent by combination of the two agents. Conclusion: Combined use of EGb and ED can decrease the expression of bax gene, yet increase bcl-2 expression to inhibit the nerve cell apoptosis and quicken the neurofunctional recovery, suggesting that the two agents play synergistic roles in protecting the brain from cerebral ischemic reperfusion injury.%目的:观察银杏叶提取物(EGb)与依达拉奉(ED)联合应用对气虚血瘀型脑缺血再灌注大鼠脑组织细胞凋亡率及bcl-2/bax表达的影响.方法:采用饥饿、疲劳、高脂饮食等复制大鼠气虚血瘀模型,再用线栓法阻断大脑中动脉2 h,再灌注治疗72 h后,观察EGb、ED及EGb+ED组对气虚血瘀型脑缺血再灌注损伤大鼠脑组织细胞凋亡率及bcl-2/bax表达的影响.结果:与模型组比较,EGb、ED及EGb+ED组均能降低气虚血瘀型脑缺血再灌注损伤大鼠脑组织凋亡细胞数(P<0.01),下调bax基因表达,上调bcl-2基因表达,减轻神经细胞损伤(P<0.01),两药联用

  18. On Standard Nomenclature of Basic Chinese Medical Terms (VB)

    Institute of Scientific and Technical Information of China (English)

    谢竹藩

    2004-01-01

    The common disorders of qi includes diminished functions of qi and disturbances in qi movement. The former usually originate from qi deficiency (气虚[qi xu]), and the latter may be further divided into qi depression (气郁[qi yu]),