WorldWideScience

Sample records for project xl preliminary

  1. 77 FR 9231 - Lock+ Hydro Friends Fund XL; FFP Project 56, LLC; Notice Announcing Preliminary Permit Drawing

    Science.gov (United States)

    2012-02-16

    ...+ Hydro Friends Fund XL; FFP Project 56, LLC; Notice Announcing Preliminary Permit Drawing The Commission..., or her designee, will conduct a random drawing to determine the filing priority of the applicants... section 4.37 of its regulations.\\2\\ The priority established by this drawing will be used to determine...

  2. 40 CFR 258.41 - Project XL Bioreactor Landfill Projects.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Project XL Bioreactor Landfill... WASTES CRITERIA FOR MUNICIPAL SOLID WASTE LANDFILLS Design Criteria § 258.41 Project XL Bioreactor Landfill Projects. (a) Buncombe County, North Carolina Project XL Bioreactor Landfill Requirements...

  3. 40 CFR 262.90 - Project XL for Public Utilities in New York State.

    Science.gov (United States)

    2010-07-01

    ... compliance history or other appropriate factors. (f) At any time, a Utility may add or remove UCCF... following information: (i) A brief description of the XL project, the intended new use of the facility, and... compliance history or other appropriate factors, the acknowledgment may impose conditions in addition to...

  4. 3XL

    DEFF Research Database (Denmark)

    Xiufeng, Liu; Thomsen, Christian; Pedersen, Torben Bach

    2012-01-01

    This paper demonstrates the use of 3XL, a DBMS-based triple-store for OWL Lite data. 3XL is characterized by its use of a database schema specialized for the data to represent. The specialized database schema uses object-relational features -- particularly inheritance -- and partitions the data...

  5. 75 FR 22890 - Notice of Extension of Public Comment Period for the Proposed Keystone XL Pipeline Project Draft...

    Science.gov (United States)

    2010-04-30

    ... notice that listed the public comment meetings and additional information on the DEIS was published in.... By mail addressed to: Elizabeth Orlando, Keystone XL Project Manager, U.S. Department of State, OES... screening. Fax to: (202) 647-1052, attention Elizabeth Orlando. FOR FURTHER INFORMATION CONTACT: For...

  6. XL-100S microprogrammable processor

    International Nuclear Information System (INIS)

    Gorbunov, N.V.; Guzik, Z.; Sutulin, V.A.; Forytski, A.

    1983-01-01

    The XL-100S microprogrammable processor providing the multiprocessor operation mode in the XL system crate is described. The processor meets the EUR 6500 CAMAC standards, address up to 4 Mbyte memory, and interacts with 7 CAMAC branchas. Eight external requests initiate operations preset by a sequence of microcommands in a memory of the capacity up to 64 kwords of 32-Git. The microprocessor architecture allows one to emulate commands of the majority of mini- or micro-computers, including floating point operations. The XL-100S processor may be used in various branches of experimental physics: for physical experiment apparatus control, fast selection of useful physical events, organization of the of input/output operations, organization of direct assess to memory included, etc. The Am2900 microprocessor set is used as an elementary base. The device is made in the form of a single width CAMAC module

  7. Bupropion XL-induced motor and vocal tics.

    Science.gov (United States)

    Kayhan, Fatih; Uguz, Faruk; Kayhan, Ayşegül; Toktaş, Fikriye Ilay

    2014-01-01

    Tics are stereotypical repetitive involuntary movements (motor tics) or sounds (vocal tics). Although the emergence of tics were reported in a few cases with the use of selective serotonin reuptake inhibitors, there was no case with bupropion extended-release (Bupropion XL). The current case report presents a male patient developing motor and vocal tics with the use of bupropion XL.

  8. New Meteorlogical Data for Ventsar XL

    Energy Technology Data Exchange (ETDEWEB)

    T. Foley; Jannik, T.

    2010-06-13

    Every five years Savannah River National Laboratory (SRNL) generates an updated meteorological database to facilitate dosimetric calculations of accident and routine release scenarios for onsite and offsite populations. This information becomes the input of various environmental dosimetry codes run by the Environmental Dosimetry Group (EDG) at SRNL. The three most recent databases prior to the current one were completed for the time periods 1987-1991, 1992-1996, and 1997-2001. The current database covers the period 2002-2006. This study represents a portion of a larger study to compare the meteorological data among these four five-year periods and focuses on updating VENTSAR XL{copyright} for the current meteorological database. The updated meteorological data are also applied in other dosimetry models approved for risk and dose assessment at Savannah River Site (SRS). VENTSAR XL{copyright} is a Gaussian Plume model that includes building effects and plume rise. The typical input involves the location of the release, building dimensions, distance to the building, release height, vent diameter, vent gas temperature, gas molecular weight, ambient air temperature, breathing rate, meteorological conditions, radionuclides and their amount released. The output is easily converted into tables and graphs for further analysis and shows the concentrations and pathway doses for each of the incremental downwind distances. VENTSAR XL{copyright} has been used at SRS to investigate building effects such as reactor cooling towers in support of safety analyses. VENTSAR XL{copyright} has also been applied to Good Engineering Practice (GEP) stack height evaluations for various projects at SRS. In accordance with the Clean Air Act Amendments of 1977, GEP must be used in determining the height of any stack that will be used to disperse routine emissions. With respect to stack heights, the GEP height is 'the height necessary to ensure that emissions from the stack do not result in

  9. Atomic structure calculations of Mo XV-XL

    International Nuclear Information System (INIS)

    Kubo, Hirotaka; Sugie, Tatsuo; Shiho, Makoto; Suzuki, Yasuo; Ishii, Keishi; Maeda, Hikosuke.

    1986-06-01

    Energy levels and oscillator strengths were calculated for Mo XV - Mo XL. The computer program for atomic structure calculation, developed by Dr. Robert D. Cowan, Los Alamos National Laboratory, was used in the present work. The scaled energy parameters were empirically determined from the observed spectral data. We present wavelengths and transition probabilities of Mo XV-XL. Energy levels and spectral patterns are presented in figures that are useful for the identification of spectral lines. (author)

  10. 3XL

    DEFF Research Database (Denmark)

    Liu, Xiufeng; Thomsen, Christian; Pedersen, Torben Bach

    2011-01-01

    An increasing number of (semantic) web applications store a very large number of (subject, predicate, object) triples in specialized storage engines called triple-stores. Often, triple-stores are used mainly as plain data stores, i.e., for inserting and retrieving large amounts of triples, but no....../or predicate is known. Extensive experiments with a PostgreSQL-based implementation show that 3XL performs very well for such operations and that the performance is comparable to state-of-the-art triple-stores....

  11. Preliminary engineering cost trends for highway projects.

    Science.gov (United States)

    2011-10-21

    Preliminary engineering (PE) for a highway project encompasses two efforts: planning to minimize the physical, social, and human environmental impacts of projects and engineering design to deliver the best alternative. PE efforts begin years in advan...

  12. Penerapan Balanced Scorecard untuk Menilai Kinerja PT XL Axiata Tbk dalam Mencapai Strateginya

    Directory of Open Access Journals (Sweden)

    Kartika Dewi

    2015-08-01

    Full Text Available This research is conducted to evaluate performance of PT XL Axiata Tbk using Balanced Score Card. The writer made design and implemented BSC in PT XL Axiata Tbk to convince its vision, mision and strategies are alligned. The method of this research is qualitative descriptive. Primary data were teken through questioners and interviewed with employees and customers.Secondary data were taken from annual report published at company website.The result of this research for Financial Perspective is PT XL Axiata Tbk needs to improve its financial ratio, The result of this research for Customer Perspective is PT XL Axiata Tbk needs to improve its customer satisfaction, The result of this research for Internal Business Process Perspective is PT XL Axiata Tbk needs to maintenance its good result, The result of this research for Learning and Growth is PT XL Axiata Tbk needs to maintenance good working environment. The final conclusion from this research at PT XL Axiata Tbk proved the company performance works toward its strategy, make a continous improvement and make a stable profit through the years taken as a sample.

  13. Eliminating Legionella by inhibiting BCL-XL to induce macrophage apoptosis.

    Science.gov (United States)

    Speir, Mary; Lawlor, Kate E; Glaser, Stefan P; Abraham, Gilu; Chow, Seong; Vogrin, Adam; Schulze, Keith E; Schuelein, Ralf; O'Reilly, Lorraine A; Mason, Kylie; Hartland, Elizabeth L; Lithgow, Trevor; Strasser, Andreas; Lessene, Guillaume; Huang, David C S; Vince, James E; Naderer, Thomas

    2016-02-24

    Human pathogenic Legionella replicate in alveolar macrophages and cause a potentially lethal form of pneumonia known as Legionnaires' disease(1). Here, we have identified a host-directed therapeutic approach to eliminate intracellular Legionella infections. We demonstrate that the genetic deletion, or pharmacological inhibition, of the host cell pro-survival protein BCL-XL induces intrinsic apoptosis of macrophages infected with virulent Legionella strains, thereby abrogating Legionella replication. BCL-XL is essential for the survival of Legionella-infected macrophages due to bacterial inhibition of host-cell protein synthesis, resulting in reduced levels of the short-lived, related BCL-2 pro-survival family member, MCL-1. Consequently, a single dose of a BCL-XL-targeted BH3-mimetic therapy, or myeloid cell-restricted deletion of BCL-XL, limits Legionella replication and prevents lethal lung infections in mice. These results indicate that repurposing BH3-mimetic compounds, originally developed to induce cancer cell apoptosis, may have efficacy in treating Legionnaires' and other diseases caused by intracellular microbes.

  14. A Synthesis of Hybrid RANS/LES CFD Results for F-16XL Aircraft Aerodynamics

    Science.gov (United States)

    Luckring, James M.; Park, Michael A.; Hitzel, Stephan M.; Jirasek, Adam; Lofthouse, Andrew J.; Morton, Scott A.; McDaniel, David R.; Rizzi, Arthur M.

    2015-01-01

    A synthesis is presented of recent numerical predictions for the F-16XL aircraft flow fields and aerodynamics. The computational results were all performed with hybrid RANS/LES formulations, with an emphasis on unsteady flows and subsequent aerodynamics, and results from five computational methods are included. The work was focused on one particular low-speed, high angle-of-attack flight test condition, and comparisons against flight-test data are included. This work represents the third coordinated effort using the F-16XL aircraft, and a unique flight-test data set, to advance our knowledge of slender airframe aerodynamics as well as our capability for predicting these aerodynamics with advanced CFD formulations. The prior efforts were identified as Cranked Arrow Wing Aerodynamics Project International, with the acronyms CAWAPI and CAWAPI-2. All information in this paper is in the public domain.

  15. S, M, L, XL: SEBUAH PANDANGAN PERALIHAN MODERN URBANISME MENUJU POSTMODERN URBANISME

    Directory of Open Access Journals (Sweden)

    , Affrilyno

    2015-01-01

    Full Text Available Teori Bigness yang digulirkan Rem Koolhaas merupakan teori yang menurut Rem Koolhaas mampu menghasilkan logika sendiri. Sekalipun teori ini dianggap sebagai bentuk yang berbeda dalam wacana arsitektur, namun keberadaannya memiliki pertumbuhan tersendiri. Ihwal teori ini berakar pada tatanan program Manhattanism yang ditulis Rem Koolhaas pada bukunya, Delirious New York (1978. Pada buku selanjutnya, S, M, L, XL (1995, Rem Koolhaas secara lebih terperinci memberikan implementasi aktual dari Manhattanism melalui berbagai proyek yang terealisasi maupun tidak terealisasi beserta tulisan-tulisan yang melingkupinya. Melalui karya tekstualnya, Rem Koolhaas telah mengembangkan pendekatan yang spesifik terhadap urbanisme dan arsitektur. Terkait problematika dalam arsitektur dan urbanisme yang menggulirkan permasalahan terhadap penolakan kompleksitas, kurangnya kontrol, oposisi, kontradiksi, dan skala yang besar, Rem Koolhaas justru merangkul kondisi ini dan menyatakannya sebagai titik awal untuk proyek-proyek mereka. Dalam konteks urban secara spesifik, Rem Koolhaas menyatakan permasalahan urban tidak lagi dapat dikendalikan dengan cara 'klasik' Modernisme. Permasalahan yang ada selanjutnya berfungsi sebagai sarana struktural untuk mengakomodasi permasalahan yang tidak dapat dikontrol. Isu-isu ini selanjutnya berperan sebagai instrumen baru dalam tatanan urbanisme dan arsitektur   Theory of Bigness as Koolhaas refers to it generates its own logic. Although the concept suffers from neglect in architectural discourse, it has prospered on its own. The program for Manhattanism has been established in 'Delirious New York' (1978. Furthermore, in the next book, S, M, L, XL (1995, Rem Koolhaas gives a record of the actual implementation of Manhattanism throughout the various (unrealized projects and texts. Through his books, Rem Koolhaas has developed a very specific approach towards urbanism and architecture. Related to the scope of the problems in

  16. 75 FR 20265 - Airworthiness Directives; Liberty Aerospace Incorporated Model XL-2 Airplanes

    Science.gov (United States)

    2010-04-19

    ... Office, 1701 Columbia Avenue, College Park, Georgia 30337; telephone: (404) 474-5524; facsimile: (404... Airworthiness Directives; Liberty Aerospace Incorporated Model XL-2 Airplanes AGENCY: Federal Aviation...-08- 05, which applies to certain Liberty Aerospace Incorporated Model XL-2 airplanes. AD 2009-08-05...

  17. Pan-Cancer Analysis Links PARK2 to BCL-XL-Dependent Control of Apoptosis

    Directory of Open Access Journals (Sweden)

    Yongxing Gong

    2017-02-01

    Full Text Available Mutation of the PARK2 gene can promote both Parkinson's Disease and cancer, yet the underlying mechanisms of how PARK2 controls cellular physiology is incompletely understood. Here, we show that the PARK2 tumor suppressor controls the apoptotic regulator BCL-XL and modulates programmed cell death. Analysis of approximately 10,000 tumor genomes uncovers a striking pattern of mutual exclusivity between PARK2 genetic loss and amplification of BCL2L1, implicating these genes in a common pathway. PARK2 directly binds to and ubiquitinates BCL-XL. Inactivation of PARK2 leads to aberrant accumulation of BCL-XL both in vitro and in vivo, and cancer-specific mutations in PARK2 abrogate the ability of the ubiquitin E3 ligase to target BCL-XL for degradation. Furthermore, PARK2 modulates mitochondrial depolarization and apoptosis in a BCL-XL-dependent manner. Thus, like genes at the nodal points of growth arrest pathways such as p53, the PARK2 tumor suppressor is able to exert its antiproliferative effects by regulating both cell cycle progression and programmed cell death.

  18. Politics, proximity and the pipeline: Mapping public attitudes toward Keystone XL

    International Nuclear Information System (INIS)

    Gravelle, Timothy B.; Lachapelle, Erick

    2015-01-01

    The politics of oil pipelines have become increasingly salient in American politics in recent years. In particular, debates about economic benefits, energy security and environmental impact have been provoked by the proposed Keystone XL pipeline expansion intended to take bitumen from northern Alberta in Canada to refineries on the Gulf Coast in Texas. Drawing on data from recent surveys conducted by the Pew Research Center, this article asks a series of questions. What levels of support for (and opposition to) the pipeline exist among the American public? What are the roles of political factors (such as party identification and ideology), economic attitudes, environmental attitudes and proximity to the proposed pipeline route in shaping attitudes toward the pipeline? And how do political factors and proximity to the pipeline interact? We find that partisanship and ideology drive attitudes toward the Keystone XL pipeline, and that the effect of ideology is attenuated by proximity to the proposed route. The policy implications of these findings for energy infrastructure siting controversies are discussed. -- Highlights: •Americans are divided on the Keystone XL energy pipeline. •Attitudes toward Keystone XL are driven by political party identification and ideology. •Attitudes toward the pipeline are also shaped by attitudes toward the economy and global warming. •The effect of proximity on attitudes toward Keystone XL is non-linear. •Spatial proximity to the pipeline attenuates the effect of ideology

  19. Next Generation Nuclear Plant Project Preliminary Project Management Plan

    International Nuclear Information System (INIS)

    Dennis J. Harrell

    2006-01-01

    This draft preliminary project management plan presents the conceptual framework for the Next Generation Nuclear Plant (NGNP) Project, consistent with the authorization in the Energy Policy Act of 2005. In developing this plan, the Idaho National Laboratory has considered three fundamental project planning options that are summarized in the following section. Each of these planning options is literally compliant with the Energy Policy Act of 2005, but each emphasizes different approaches to technology development risks, design, licensing and construction risks, and to the extent of commercialization support provided to the industry. The primary focus of this draft preliminary project management plan is to identify those activities important to Critical Decision-1, at which point a decision on proceeding with the NGNP Project can be made. The conceptual project framework described herein is necessary to establish the scope and priorities for the technology development activities. The framework includes: A reference NGNP prototype concept based on what is judged to be the lowest risk technology development that would achieve the needed commercial functional requirements to provide an economically competitive nuclear heat source and hydrogen production capability. A high-level schedule logic for design, construction, licensing, and acceptance testing. This schedule logic also includes an operational shakedown period that provides proof-of-principle to establish the basis for commercialization decisions by end-users. An assessment of current technology development plans to support Critical Decision-1 and overall project progress. The most important technical and programmatic uncertainties (risks) are evaluated, and potential mitigation strategies are identified so that the technology development plans may be modified as required to support ongoing project development. A rough-order-of-magnitude cost evaluation that provides an initial basis for budget planning. This

  20. Implementing national nuclear safety plan at the preliminary stage of nuclear power project development

    International Nuclear Information System (INIS)

    Xue Yabin; Cui Shaozhang; Pan Fengguo; Zhang Lizhen; Shi Yonggang

    2014-01-01

    This study discusses the importance of nuclear power project design and engineering methods at the preliminary stage of its development on nuclear power plant's operational safety from the professional view. Specifically, we share our understanding of national nuclear safety plan's requirement on new reactor accident probability, technology, site selection, as well as building and improving nuclear safety culture and strengthening public participation, with a focus on plan's implications on preliminary stage of nuclear power project development. Last, we introduce China Huaneng Group's work on nuclear power project preliminary development and the experience accumulated during the process. By analyzing the siting philosophy of nuclear power plant and the necessity of building nuclear safety culture at the preliminary stage of nuclear power project development, this study explicates how to fully implement the nuclear safety plan's requirements at the preliminary stage of nuclear power project development. (authors)

  1. Business System Planning Project, Preliminary System Design

    International Nuclear Information System (INIS)

    EVOSEVICH, S.

    2000-01-01

    CH2M HILL Hanford Group, Inc. (CHG) is currently performing many core business functions including, but not limited to, work control, planning, scheduling, cost estimating, procurement, training, and human resources. Other core business functions are managed by or dependent on Project Hanford Management Contractors including, but not limited to, payroll, benefits and pension administration, inventory control, accounts payable, and records management. In addition, CHG has business relationships with its parent company CH2M HILL, U.S. Department of Energy, Office of River Protection and other River Protection Project contractors, government agencies, and vendors. The Business Systems Planning (BSP) Project, under the sponsorship of the CH2M HILL Hanford Group, Inc. Chief Information Officer (CIO), have recommended information system solutions that will support CHG business areas. The Preliminary System Design was developed using the recommendations from the Alternatives Analysis, RPP-6499, Rev 0 and will become the design base for any follow-on implementation projects. The Preliminary System Design will present a high-level system design, providing a high-level overview of the Commercial-Off-The-Shelf (COTS) modules and identify internal and external relationships. This document will not define data structures, user interface components (screens, reports, menus, etc.), business rules or processes. These in-depth activities will be accomplished at implementation planning time

  2. Preliminary Project Execution Plan for the Remote-Handled Low-Level Waste Disposal Project

    Energy Technology Data Exchange (ETDEWEB)

    David Duncan

    2011-05-01

    This preliminary project execution plan (PEP) defines U.S. Department of Energy (DOE) project objectives, roles and responsibilities of project participants, project organization, and controls to effectively manage acquisition of capital funds for construction of a proposed remote-handled low-level waste (LLW) disposal facility at the Idaho National Laboratory (INL). The plan addresses the policies, requirements, and critical decision (CD) responsibilities identified in DOE Order 413.3B, 'Program and Project Management for the Acquisition of Capital Assets.' This plan is intended to be a 'living document' that will be periodically updated as the project progresses through the CD process to construction and turnover for operation.

  3. Preliminary Project Execution Plan for the Remote-Handled Low-Level Waste Disposal Project

    International Nuclear Information System (INIS)

    Duncan, David

    2011-01-01

    This preliminary project execution plan (PEP) defines U.S. Department of Energy (DOE) project objectives, roles and responsibilities of project participants, project organization, and controls to effectively manage acquisition of capital funds for construction of a proposed remote-handled low-level waste (LLW) disposal facility at the Idaho National Laboratory (INL). The plan addresses the policies, requirements, and critical decision (CD) responsibilities identified in DOE Order 413.3B, 'Program and Project Management for the Acquisition of Capital Assets.' This plan is intended to be a 'living document' that will be periodically updated as the project progresses through the CD process to construction and turnover for operation.

  4. Flight Test Results for the F-16XL With a Digital Flight Control System

    Science.gov (United States)

    Stachowiak, Susan J.; Bosworth, John T.

    2004-01-01

    In the early 1980s, two F-16 airplanes were modified to extend the fuselage length and incorporate a large area delta wing planform. These two airplanes, designated the F-16XL, were designed by the General Dynamics Corporation (now Lockheed Martin Tactical Aircraft Systems) (Fort Worth, Texas) and were prototypes for a derivative fighter evaluation program conducted by the United States Air Force. Although the concept was never put into production, the F-16XL prototypes provided a unique planform for testing concepts in support of future high-speed supersonic transport aircraft. To extend the capabilities of this testbed vehicle the F-16XL ship 1 aircraft was upgraded with a digital flight control system. The added flexibility of a digital flight control system increases the versatility of this airplane as a testbed for aerodynamic research and investigation of advanced technologies. This report presents the handling qualities flight test results covering the envelope expansion of the F-16XL with the digital flight control system.

  5. Characterization of steel 70XL used in the manufacture of balls for the clinker's milling

    Directory of Open Access Journals (Sweden)

    Eider Gresesqui-Lobaina

    2017-10-01

    Full Text Available The present article deals with the wear of the balls used for the grinding of the clinker in the processes of obtaining cement. Three specimens of different steel were made: one of steel AISI 4140, with which balls are forged for the milling process; another 70XL steel (70 XL with normalized, tempered and tempered thermal treatments; and the third, of equal material that the second but without treatment. For the metallographic observation the samples were made with dimensions of 10 mm in diameter and 8 mm in thickness, revealing for AISI 4140 steel a structure of martensitic type with some presence of acicular ferrite. For the 70XL steel without heat treatment the presence of ferrite and cementite was observed, while the steel 70XL with heat treatment showed in the limits of free cementite grain in a pearly matrix, which resulted in a higher hardness (up to HRC 59 , 8 and lower gravimetric wear compared to other materials. Therefore it is recommended as the most suitable for the manufacture of balls for grinding minerals 70XL steel with heat treatment.

  6. Steady-state pharmacokinetics of fluvastatin in healthy subjects following a new extended release fluvastatin tablet, Lescol XL.

    Science.gov (United States)

    Barilla, Denise; Prasad, Pratapa; Hubert, Martine; Gumbhir-Shah, Kavita

    2004-03-01

    This was an open-label, randomized, three-period, three-treatment, multiple dose, crossover study in 12 healthy male and female subjects. This study evaluated single dose and steady-state pharmacokinetics of fluvastatin following single and multiple dose administrations of a new extended release fluvastatin 8 h matrix tablet, Lescol XL 80 mg and 160 mg doses once a day. The study also included a twice a day administration of an immediate release (IR) form of fluvastatin capsule, Lescol, for comparative purposes. All doses were administered for 7 days. The safety and tolerability were also assessed. The pharmacokinetics of fluvastatin were evaluated on days 1 and 7 following each treatment. Fluvastatin systemic exposure was 50% less when administered as Lescol XL 80 mg qd compared with Lescol IR 40 mg bid. Conversely, fluvastatin systemic exposure was 22% higher when administered as Lescol XL 160 mg qd compared with Lescol IR 40 mg bid. Single doses of Lescol XL 80 mg and 160 mg were dose proportional but, deviation (30%) from dose proportionality was observed for the Lescol XL 160 mg at steady-state. There appeared to be moderate (20%-40%) accumulation of serum fluvastatin maximal concentrations and exposure after multiple doses of Lescol XL tablets. Both Lescol XL 80 mg and 160 mg showed delayed absorption and longer apparent elimination half-life compared with fluvastatin IR capsule. Single and multiple doses of fluvastatin were generally well tolerated in this healthy volunteer population. Adverse event profiles were consistent with the published safety profile of the marketed formulations. Aside from one incidence of creatine phosphokinase (CPK) elevation (following Lescol XL 160 mg qd treatment), there were no safety concerns with any of the treatments when administered acutely (7 days). Copyright 2004 John Wiley & Sons, Ltd.

  7. Bcl-XL represents a druggable molecular vulnerability during aurora B inhibitor-mediated polyploidization.

    Science.gov (United States)

    Shah, O Jameel; Lin, Xiaoyu; Li, Leiming; Huang, Xiaoli; Li, Junling; Anderson, Mark G; Tang, Hua; Rodriguez, Luis E; Warder, Scott E; McLoughlin, Shaun; Chen, Jun; Palma, Joann; Glaser, Keith B; Donawho, Cherrie K; Fesik, Stephen W; Shen, Yu

    2010-07-13

    Aurora kinase B inhibitors induce apoptosis secondary to polyploidization and have entered clinical trials as an emerging class of neocytotoxic chemotherapeutics. We demonstrate here that polyploidization neutralizes Mcl-1 function, rendering cancer cells exquisitely dependent on Bcl-XL/-2. This "addiction" can be exploited therapeutically by combining aurora kinase inhibitors and the orally bioavailable BH3 mimetic, ABT-263, which inhibits Bcl-XL, Bcl-2, and Bcl-w. The combination of ABT-263 with aurora B inhibitors produces a synergistic loss of viability in a range of cell lines of divergent tumor origin and exhibits more sustained tumor growth inhibition in vivo compared with aurora B inhibitor monotherapy. These data demonstrate that Bcl-XL/-2 is necessary to support viability during polyploidization in a variety of tumor models and represents a druggable molecular vulnerability with potential therapeutic utility.

  8. Analyzing Social Media Networks with NodeXL Insights from a Connected World

    CERN Document Server

    Hansen, Derek; Smith, Marc A

    2010-01-01

    Businesses, entrepreneurs, individuals, and government agencies alike are looking to social network analysis (SNA) tools for insight into trends, connections, and fluctuations in social media. Microsoft's NodeXL is a free, open-source SNA plug-in for use with Excel. It provides instant graphical representation of relationships of complex networked data. But it goes further than other SNA tools -- NodeXL was developed by a multidisciplinary team of experts that bring together information studies, computer science, sociology, human-computer interaction, and over 20 years of visual analytic theor

  9. Improvement of exercise capacity and left ventricular diastolic function with metoprolol XL after acute myocardial infarction

    DEFF Research Database (Denmark)

    Poulsen, S H; Jensen, S E; Egstrup, K

    2000-01-01

    dysfunction after acute myocardial infarction were given metoprolol XL (n = 29) or placebo (n = 30). The effects of metoprolol XL on exercise capacity in relation to effects on LV diastolic filling were studied. Two-dimensional Doppler echocardiography and maximal symptom limited bicycle test were performed...

  10. Preliminary Study on Management of Agricultural Scientific Research Projects in the New Situation

    Institute of Scientific and Technical Information of China (English)

    Haiyan LUO; Qingqun YAO; Lizhen CHEN; Yu ZHENG

    2015-01-01

    Project management of agricultural scientific research institutions is an important section of agricultural scientific research plan management. It is of great significance for sustainable development of scientific research work of scientific research institutions. According to a series of opinions and notices about scientific and technological system reform issued by the state,and combining current situations of management of scientific research projects in scientific research institutions,this paper made a preliminary study on management of agricultural scientific research projects in the new trend. Finally,on the basis of the current situations of management of agricultural scientific research projects,it came up with pertinent recommendations,including strengthening communication and cooperation and actively declaring projects,strengthening preliminary planning of projects and establishing project information database,reinforcing project process management,ensuring on-time and high quality completion of projects,and strengthening learning and improving quality of management personnel.

  11. F-16XL ship #1 (#849) during first flight of the Digital Flight Control System (DFCS)

    Science.gov (United States)

    1997-01-01

    After completing its first flight with the Digital Flight Control System on December 16, 1997, the F-16XL #1 aircraft began a series of envelope expansion flights. On January 27 and 29, 1998, it successfully completed structural clearance tests, as well as most of the load testing Only flights at Mach 1.05 at 10,000 feet, Mach 1.1 at 15,000 feet, and Mach 1.2 at 20,000 feet remained. During the next flight, on February 4, an instrumentation problem cut short the planned envelope expansion tests. After the problem was corrected, the F-16XL returned to flight status, and on February 18 and 20, flight control and evaluation flights were made. Two more research flights were planned for the following week, but another problem appeared. During the ground start up, project personnel noticed that the leading edge flap moved without being commanded. The Digital Flight Control Computer was sent to the Lockheed-Martin facility at Fort Worth, where the problem was traced to a defective chip in the computer. After it was replaced, the F-16XL #1 flew a highly successful flight controls and handling qualities evaluation flight on March 26, clearing the way for the final tests. The final limited loads expansion flight occurred on March 31, and was fully successful. As a result, the on-site Lockheed-Martin loads engineer cleared the aircraft to Mach 1.8. The remaining two handling qualities and flight control evaluation flights were both made on April 3, 1998. These three flights concluded the flight test portion of the DFCS upgrade.

  12. 76 FR 73616 - Lock 12 Hydro Partners; FFP Project 107 LLC; Notice of Competing Preliminary Permit Applications...

    Science.gov (United States)

    2011-11-29

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Project Nos. 13214-002; 14274-000] Lock 12 Hydro Partners; FFP Project 107 LLC; Notice of Competing Preliminary Permit Applications Accepted..., 2011, Lock 12 Hydro Partners (Lock 12), and FFP Project 107 LLC (FFP 107) filed preliminary permit...

  13. 76 FR 73614 - Lock 14 Hydro Partners; FFP Project 106 LLC; Notice of Competing Preliminary Permit Applications...

    Science.gov (United States)

    2011-11-29

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Project Nos. 13213-002; 14271-000] Lock 14 Hydro Partners; FFP Project 106 LLC; Notice of Competing Preliminary Permit Applications Accepted..., 2011, Lock 14 Hydro Partners (Lock 14), and FFP Project 106 LLC (FFP 106) filed preliminary permit...

  14. Epithelium-on photorefractive intrastromal cross-linking (PiXL for reduction of low myopia

    Directory of Open Access Journals (Sweden)

    Lim WK

    2017-06-01

    Full Text Available Wee Kiak Lim,1,2 Zhi Da Soh,1 Harold Kah Yen Choi,1 Julian Thiam Siew Theng1,3 1Eagle Eye Centre, Mount Alvernia Hospital, 2Department of Ophthalmology, Tan Tock Seng Hospital, 3Department of Ophthalmology, Khoo Teck Puat Hospital, Singapore Purpose: To report the 9–12-month outcomes of a novel procedure for reduction of low myopia through epithelium-on photorefractive intrastromal cross-linking (PiXL with customized control of topographic distribution of ultraviolet (UV-fluence. Method: Myopic patients with normal (non-ectatic corneas underwent the PiXL procedure for reduction of low myopia. PiXL treatments were delivered through selective application of UVA light based on the refractive error of each patient. Clinical evaluation included safety (corrected distance visual acuity, endothelial cell count, central corneal thickness, anterior ocular health and efficacy (uncorrected distance visual acuity, manifest refraction, K-mean examinations. In addition, a patient satisfaction survey was conducted at 9 months post-procedure to evaluate patients’ subjective experience with the procedure. Results: Fourteen myopic eyes (mean manifest refraction spherical equivalent –1.62±0.6D; range –0.75 to –2.65D of 8 subjects (mean age 30 years old; range 24–51 years old were enrolled in the study. At 12 months post-procedure, a mean manifest refraction spherical equivalent reduction of 0.72±0.43D (P<0.001 was observed, with a corresponding gain in uncorrected visual acuity of 0.25 logMAR and mean K-mean flattening of 0.47±0.46D. All patients achieved best corrected visual acuity of 20/20 or better from 1 month onward. There were no cases of ocular infection or secondary changes to the crystalline lens and retina due to UV exposure, while transient corneal haze subsided gradually. Conclusion: The epithelium-on PiXL procedure was safe and effective in reducing myopic refractive error in this study with up to 12 months follow-up. Early results of

  15. Characterization of X-linked Hypohidrotic Ectodermal Dysplasia (XL-HED) Hair and Sweat Gland Phenotypes Using Phototrichogram Analysis and Live Confocal Imaging

    Science.gov (United States)

    Jones, Kyle B.; Goodwin, Alice F.; Landan, Maya; Seidel, Kerstin; Tran, Dong-Kha; Hogue, Jacob; Chavez, Miquella; Fete, Mary; Yu, Wenli; Hussein, Tarek; Johnson, Ramsey; Huttner, Kenneth; Jheon, Andrew H.; Klein, Ophir D.

    2015-01-01

    Hypohidrotic ectodermal dysplasia (HED) is the most common type of ectodermal dysplasia (ED), which encompasses a large group of syndromes that share several phenotypic features such as missing or malformed ectodermal structures, including skin, hair, sweat glands, and teeth. X-linked hypohidrotic ectodermal dysplasia (XL-HED) is associated with mutations in ectodysplasin (EDA1). Hypohidrosis due to hypoplastic sweat glands and thin, sparse hair are phenotypic features that significantly affect the daily lives of XL-HED individuals and therefore require systematic analysis. We sought to determine the quality of life of individuals with XL-HED and to quantify sweat duct and hair phenotypes using confocal imaging, pilocarpine iontophoresis, and phototrichogram analysis. Using these highly sensitive and non-invasive techniques, we demonstrated that 11/12 XL-HED individuals presented with a complete absence of sweat ducts and that none produced sweat. We determined that the thin hair phenotype observed in XL-HED was due to multiple factors, such as fewer terminal hairs with decreased thickness and slower growth rate, as well as fewer follicular units and fewer hairs per unit. The precise characterization of XL-HED phenotypes using sensitive and non-invasive techniques presented in our study will improve upon larger genotype-phenotype studies and in the assessment of future therapies in XL-HED. PMID:23687000

  16. Hellsgate Winter Range : Wildlife Mitigation Project. Preliminary Environmental Assessment.

    Energy Technology Data Exchange (ETDEWEB)

    United States. Bonneville Power Administration.

    1995-01-01

    The Bonneville Power Administration proposes funding the Hellsgate Winter Range Wildlife Mitigation Project in cooperation with the Colville Convederated Tribes and Bureau of Indian Affairs. This Preliminary Environmental Assessment examines the potential environmental effects of acquiring and managing property for wildlife and wildlife habitat within a large project area. The Propose action is intended to meet the need for mitigation of wildlife and wild life habitat that was adversely affected by the construction of Grand Coulee and Chief Joseph Dams and their reservoirs.

  17. CDF-XL: computing cumulative distribution functions of reaction time data in Excel.

    Science.gov (United States)

    Houghton, George; Grange, James A

    2011-12-01

    In experimental psychology, central tendencies of reaction time (RT) distributions are used to compare different experimental conditions. This emphasis on the central tendency ignores additional information that may be derived from the RT distribution itself. One method for analysing RT distributions is to construct cumulative distribution frequency plots (CDFs; Ratcliff, Psychological Bulletin 86:446-461, 1979). However, this method is difficult to implement in widely available software, severely restricting its use. In this report, we present an Excel-based program, CDF-XL, for constructing and analysing CDFs, with the aim of making such techniques more readily accessible to researchers, including students (CDF-XL can be downloaded free of charge from the Psychonomic Society's online archive). CDF-XL functions as an Excel workbook and starts from the raw experimental data, organised into three columns (Subject, Condition, and RT) on an Input Data worksheet (a point-and-click utility is provided for achieving this format from a broader data set). No further preprocessing or sorting of the data is required. With one click of a button, CDF-XL will generate two forms of cumulative analysis: (1) "standard" CDFs, based on percentiles of participant RT distributions (by condition), and (2) a related analysis employing the participant means of rank-ordered RT bins. Both analyses involve partitioning the data in similar ways, but the first uses a "median"-type measure at the participant level, while the latter uses the mean. The results are presented in three formats: (i) by participants, suitable for entry into further statistical analysis; (ii) grand means by condition; and (iii) completed CDF plots in Excel charts.

  18. [Comparison of the M and XL FibroScan(®) probes to estimate liver stiffness by transient elastography].

    Science.gov (United States)

    Herrero, José Ignacio; Iñarrairaegui, Mercedes; D'Avola, Delia; Sangro, Bruno; Prieto, Jesús; Quiroga, Jorge

    2014-04-01

    The FibroScan(®) XL probe has been specifically designed for obese patients to measure liver stiffness by transient elastography, but it has not been well tested in non-obese patients. The aim of this study was to compare the M and XL FibroScan(®) probes in a series of unselected obese (body mass index above 30 kg/m(2)) and non-obese patients with chronic liver disease. Two hundred and fifty-four patients underwent a transient elastography examination with both the M and XL probes. The results obtained with the two probes were compared in the whole series and in obese (n=82) and non-obese (n=167) patients separately. The reliability of the examinations was assessed using the criteria defined by Castéra et al. The proportion of reliable exams was significantly higher when the XL probe was used (83% versus 73%; P=.001). This significance was maintained in the group of obese patients (82% versus 55%; P<.001), but not in the non-obese patients (84% versus 83%). Despite a high correlation between the stiffness values obtained with the two probes (R=.897; P<.001), and a high concordance in the estimation of fibrosis obtained with the two probes (Cronbach's alpha value: 0.932), the liver stiffness values obtained with the XL probe were significantly lower than those obtained with the M probe, both in the whole series (9.5 ± 9.1 kPa versus 11.3 ± 12.6 kPa; P<0.001) and in the obese and non-obese groups. In conclusion, transient elastography with the XL probe allows a higher proportion of reliable examinations in obese patients but not in non-obese patients. Stiffness values were lower with the XL probe than with the M probe. Copyright © 2013 Elsevier España, S.L. and AEEH y AEG. All rights reserved.

  19. 76 FR 76153 - Grand Coulee Project Hydroelectric Authority; Notice of Preliminary Permit Application Accepted...

    Science.gov (United States)

    2011-12-06

    ... Project Hydroelectric Authority; Notice of Preliminary Permit Application Accepted for Filing and... Hydroelectric Project (Scooteney Inlet Project or project) to be located on the Potholes East Canal, which is an..., Grand Coulee Project Hydroelectric Authority, P.O. Box 219, Ephrata, WA 98823; phone: (509) 754-2227...

  20. Pengaruh e-CRM dan Service Quality terhadap Customer Satisfaction dan Dampaknya terhadap Customer Loyalty pada PT XL

    Directory of Open Access Journals (Sweden)

    Marshellina Marshellina

    2013-11-01

    Full Text Available This study aims to look at the influence and how much the influence of e-CRM (X1 and Quality of Service (X2 for Customer Satisfaction (Y that impact on Customer Loyalty (Z at PT XL. Data collection techniques were with questionnaires, the number of population in this study was approximately three millionrespondents, ie customers who use the product XL in West Jakarta, because the area most widely uses XL provider. Total sample was 100 respondents and the technique used was simple random sampling. The method used in this study was Pearson correlation and path analysis. Based on the results of data analysis, structural equation is Y = 0.310 + 0.330 X1 + X2 0.874 and Z = 0.005 X1 + X2 + 0.449 -0.070 + 0.903 Y, which Electronic Customer Relationship Management and the quality of service have yet to be effective in providing a positive influence for customer loyalty directly, but it must go through prior customer satisfaction as an intervening variable. Therefore, more companies should make improvements to the new way of communicating with customers via electronic media because it gives quite effective results for customer satisfaction in PT XL. Inaddition, PT XL should provide training and better development for the employees working in the company to improve the quality of service that can create customer loyalty.

  1. A systematic review on the safety of Prostar XL versus ProGlide after TAVR and EVAR

    Energy Technology Data Exchange (ETDEWEB)

    Maniotis, Christos [2nd Cardiology Department, Hellenic Red Cross Hospital of Athens, Athens (Greece); Andreou, Constantinos; Karalis, Ioannis [Interventional Cardiology Department, University Hospital of Leiden, Leiden (Netherlands); Koutouzi, Giasemi [Interventional Radiology Department, Sahlgrenska University Hospital, Gothenburg (Sweden); Agelaki, Maria [2nd Cardiology Department, Hellenic Red Cross Hospital of Athens, Athens (Greece); Koutouzis, Michael, E-mail: koutouzismike@yahoo.gr [2nd Cardiology Department, Hellenic Red Cross Hospital of Athens, Athens (Greece)

    2017-03-15

    Background: Endovascular aortic aneurysm repair (EVAR) and transfemoral transcatheter aortic valve replacement (TAVR) are widely spreading minimally invasive procedures performed mainly through the femoral artery. Prostar XL and ProGlide vascular closure devices are used in clinical practice for the hemostasis in these procedures and they have been shown to be safe and effective. Purpose: The aim of our systematic review is to compare the safety of these two devices for percutaneous closure of large arteriotomies in patients undergoing TAVR and EVAR. Methods: We searched PubMed, EMBASE, Google Scholar and the Cochrane Central Register of Controlled Trials for all randomized and observational published studies that compared Prostar XL vs. ProGlide. Relative risk was calculated by random-effects model. Review Manager 5.1 was used for statistical analysis. Results: A total number of 2909 patients were included in our analysis. The rate of overall vascular complications did not differ between Prostar XL and ProGlide {RR 1.35 (0.80–2.29), p = 0.27}. In contrary, the risk ratio of all bleeding complications with Prostar XL compared to ProGlide was 1.82 (1.47–2.24, p < 0.001) and for major and life-threatening bleeding complications was 2.48 (1.65–3.73, p < 0001, suggesting a lower bleeding risk with ProGlide). No statistical difference was found between groups for end-stage acute kidney injury (AKI), with a risk ratio of 2.14 (0.81–5.66), p = 0.05. Finally, there were no differences in in-hospital and 30-days mortality rate between the two groups (1.41, 0.56–3.54, p = 0.46 and 1.43, 0.55–3.73, p = 0.47, respectively). Conclusions: Prostar XL is associated with greater risk of any bleeding as well as life threatening bleeding compared to the ProGlide device. However, no significant differences were observed in the rate of overall vascular complications, end stage AKI and in-hospital and 30-days mortality. - Highlights: • We present a systematic review

  2. A systematic review on the safety of Prostar XL versus ProGlide after TAVR and EVAR

    International Nuclear Information System (INIS)

    Maniotis, Christos; Andreou, Constantinos; Karalis, Ioannis; Koutouzi, Giasemi; Agelaki, Maria; Koutouzis, Michael

    2017-01-01

    Background: Endovascular aortic aneurysm repair (EVAR) and transfemoral transcatheter aortic valve replacement (TAVR) are widely spreading minimally invasive procedures performed mainly through the femoral artery. Prostar XL and ProGlide vascular closure devices are used in clinical practice for the hemostasis in these procedures and they have been shown to be safe and effective. Purpose: The aim of our systematic review is to compare the safety of these two devices for percutaneous closure of large arteriotomies in patients undergoing TAVR and EVAR. Methods: We searched PubMed, EMBASE, Google Scholar and the Cochrane Central Register of Controlled Trials for all randomized and observational published studies that compared Prostar XL vs. ProGlide. Relative risk was calculated by random-effects model. Review Manager 5.1 was used for statistical analysis. Results: A total number of 2909 patients were included in our analysis. The rate of overall vascular complications did not differ between Prostar XL and ProGlide {RR 1.35 (0.80–2.29), p = 0.27}. In contrary, the risk ratio of all bleeding complications with Prostar XL compared to ProGlide was 1.82 (1.47–2.24, p < 0.001) and for major and life-threatening bleeding complications was 2.48 (1.65–3.73, p < 0001, suggesting a lower bleeding risk with ProGlide). No statistical difference was found between groups for end-stage acute kidney injury (AKI), with a risk ratio of 2.14 (0.81–5.66), p = 0.05. Finally, there were no differences in in-hospital and 30-days mortality rate between the two groups (1.41, 0.56–3.54, p = 0.46 and 1.43, 0.55–3.73, p = 0.47, respectively). Conclusions: Prostar XL is associated with greater risk of any bleeding as well as life threatening bleeding compared to the ProGlide device. However, no significant differences were observed in the rate of overall vascular complications, end stage AKI and in-hospital and 30-days mortality. - Highlights: • We present a systematic review

  3. In vitro and in vivo evaluation of the probiotic attributes of Lactobacillus kefiranofaciens XL10 isolated from Tibetan kefir grain.

    Science.gov (United States)

    Xing, Zhuqing; Tang, Wei; Geng, Weitao; Zheng, Yongna; Wang, Yanping

    2017-03-01

    Lactobacillus kefiranofaciens XL10, with a high yield of extracellular polysaccharide (EPS), is isolated from Tibetan kefir grain and benefits the health of human beings and has been considered to exhibit probiotic potential in vitro and in vivo. The probiotic function of the strain was studied extensively, viz., acid and bile salt tolerances, cell surface hydrophobicity and autoaggregation, the modulation of gut microbiota, and the distribution and colonization of XL10 in the mouse intestinal tract after oral administration. XL10 could survive 3-h incubation at pH 3.5 and exhibited cell surface hydrophobicity of ∼79.9% and autoaggregation of ∼27.8%. After continuous oral administration of XL10 for 2 weeks, the Bifidobacteriaceae family increased, accompanied by an observable decline in Proteobacteria phyla in the tested mice. Butyrivibrio and Pseudobutyrivibrio, recognized as butyric acid-producing bacteria, could also be detected at day 7 and day 14, respectively. The most abundant community in the mouse gut had formed by day 14. Additionally, we found that XL10 successfully adhered to the mucous tissue and colonized the ileum of the mice based on fluorescence imaging, flow cytometry, and qPCR. Our results suggested that XL10 has excellent probiotic properties and represents an alternative for exploitation in the development of novel functional foods.

  4. King County Metro Battery Electric Bus Demonstration: Preliminary Project Results

    Energy Technology Data Exchange (ETDEWEB)

    2017-05-22

    The U.S. Federal Transit Administration (FTA) funds a variety of research projects that support the commercialization of zero-emission bus technology. To evaluate projects funded through these programs, FTA has enlisted the help of the National Renewable Energy Laboratory (NREL) to conduct third-party evaluations of the technologies deployed under the FTA programs. NREL works with the selected agencies to evaluate the performance of the zero-emission buses compared to baseline conventional buses in similar service. The evaluation effort will advance the knowledge base of zero-emission technologies in transit bus applications and provide 'lessons learned' to aid other fleets in incrementally introducing next generation zero-emission buses into their operations. This report provides preliminary performance evaluation results from a demonstration of three zero-emission battery electric buses at King County Metro in King County, Washington. NREL developed this preliminary results report to quickly disseminate evaluation results to stakeholders. Detailed evaluation results will be published in future reports.

  5. 77 FR 7574 - Grand Coulee Project Hydroelectric Authority; Notice of Preliminary Permit Application Accepted...

    Science.gov (United States)

    2012-02-13

    ... Project Hydroelectric Authority; Notice of Preliminary Permit Application Accepted for Filing and Soliciting Comments and Motions To Intervene On January 13, 2012, the Grand Coulee Project Hydroelectric... study the feasibility of the P.E. Scooteney Wasteway Hydroelectric Project, to be located on the P.E...

  6. 77 FR 7143 - Grand Coulee Project Hydroelectric Authority; Notice of Preliminary Permit Application Accepted...

    Science.gov (United States)

    2012-02-10

    ... Project Hydroelectric Authority; Notice of Preliminary Permit Application Accepted for Filing and Soliciting Comments and Motions To Intervene On January 13, 2012, the Grand Coulee Project Hydroelectric... study the feasibility of the P.E. 46A Wasteway Hydroelectric Project, to be located on the P.E. 46A...

  7. Induction of Apoptosis by the Severe Acute Respiratory Syndrome Coronavirus 7a Protein Is Dependent on Its Interaction with the Bcl-XL Protein▿

    Science.gov (United States)

    Tan, Ying-Xim; Tan, Timothy H. P.; Lee, Marvin J.-R.; Tham, Puay-Yoke; Gunalan, Vithiagaran; Druce, Julian; Birch, Chris; Catton, Mike; Fu, Nai Yang; Yu, Victor C.; Tan, Yee-Joo

    2007-01-01

    The severe acute respiratory syndrome coronavirus (SARS-CoV) 7a protein, which is not expressed by other known coronaviruses, can induce apoptosis in various cell lines. In this study, we show that the overexpression of Bcl-XL, a prosurvival member of the Bcl-2 family, blocks 7a-induced apoptosis, suggesting that the mechanism for apoptosis induction by 7a is at the level of or upstream from the Bcl-2 family. Coimmunoprecipitation experiments showed that 7a interacts with Bcl-XL and other prosurvival proteins (Bcl-2, Bcl-w, Mcl-1, and A1) but not with the proapoptotic proteins (Bax, Bak, Bad, and Bid). A good correlation between the abilities of 7a deletion mutants to induce apoptosis and to interact with Bcl-XL was observed, suggesting that 7a triggers apoptosis by interfering directly with the prosurvival function of Bcl-XL. Interestingly, amino acids 224 and 225 within the C-terminal transmembrane domain of Bcl-XL are essential for the interaction with the 7a protein, although the BH3 domain of Bcl-XL also contributes to this interaction. In addition, fractionation experiments showed that 7a colocalized with Bcl-XL at the endoplasmic reticulum as well as the mitochondria, suggesting that they may form complexes in different membranous compartments. PMID:17428862

  8. Preliminary project of installation for separation tubes tests-ITTS

    International Nuclear Information System (INIS)

    Rocha, Z.

    1984-01-01

    A consolidation of actual ideas about installation, entitled ''Installation to separation tubes tests-ITTS'', expected to CDTN is presented. The project bases, the testing to be realized, the procedures to be obeyed during the operation, the components and the space required by installation and auxiliary equipments, the presumable origin of components (nacional and international), including a preliminary list of building and operation costs are described. (author) [pt

  9. 76 FR 75542 - Porcupine Dam Hydropower Project; Notice of Preliminary Permit Application Accepted for Filing...

    Science.gov (United States)

    2011-12-02

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Project No. 14290-000] Porcupine Dam Hydropower Project; Notice of Preliminary Permit Application Accepted for Filing and Soliciting Comments...), proposing to study the feasibility of the Porcupine Dam Hydropower Project to be located on the East Fork of...

  10. Solid Waste Operations Complex W-113: Project cost estimate. Preliminary design report. Volume IV

    International Nuclear Information System (INIS)

    1995-01-01

    This document contains Volume IV of the Preliminary Design Report for the Solid Waste Operations Complex W-113 which is the Project Cost Estimate and construction schedule. The estimate was developed based upon Title 1 material take-offs, budgetary equipment quotes and Raytheon historical in-house data. The W-113 project cost estimate and project construction schedule were integrated together to provide a resource loaded project network

  11. 76 FR 76156 - Grand Coulee Project Hydroelectric Authority; Notice of Preliminary Permit Application Accepted...

    Science.gov (United States)

    2011-12-06

    ... Project Hydroelectric Authority; Notice of Preliminary Permit Application Accepted for Filing and... Federal Power Act (FPA), proposing to study the feasibility of the Scooteney Outlet Drop Hydroelectric..., Grand Coulee Project Hydroelectric Authority, P.O. Box 219, Ephrata, WA 98823; phone: (509) 754-2227...

  12. Preliminary project of s Thomson scattering system for the ETE tokamak

    International Nuclear Information System (INIS)

    Berni, Luiz Angelo

    1997-01-01

    This report presents the preliminary project of the injection and laser light block system for the Thomson (ET) scattering diagnostic to be implanted at the ETE spheric tokamak of the Instituto Nacional de Pesquisas Espaciais (INPE/LAP). Also, a scanning system for the optics of scattered light

  13. 78 FR 34092 - Lock+ Hydro Friends Fund XXX, LLC; FFP Project 121, LLC; Notice of Competing Preliminary Permit...

    Science.gov (United States)

    2013-06-06

    .... 14504-000] Lock+ Hydro Friends Fund XXX, LLC; FFP Project 121, LLC; Notice of Competing Preliminary... Applications Lock+ Hydro Friends Fund XXX, LLC and FFP Project 121, LLC filed preliminary permit applications... regular business day. See id. at 385.2001(a)(2). Lock+ Hydro Friends Fund XXX, LLC's application is for a...

  14. Modelled and Observed Diurnal SST Signals: "SSTDV:R.EX.-IM.A.M." Project Preliminary Results

    DEFF Research Database (Denmark)

    Karagali, Ioanna; Høyer, Jacob; LeBorgne, Pierre

    2013-01-01

    This study presents some of the preliminary results from the ESA Support To Science Element (STSE) funded project on the Diurnal Variability of the Sea Surface Temperature, regarding its Regional Extend and Implications in Atmospheric Modelling (SSTDV:R.EX.–IM.A.M.). During this phase of the proj......This study presents some of the preliminary results from the ESA Support To Science Element (STSE) funded project on the Diurnal Variability of the Sea Surface Temperature, regarding its Regional Extend and Implications in Atmospheric Modelling (SSTDV:R.EX.–IM.A.M.). During this phase...

  15. 77 FR 4290 - Conway Ranch Hydropower Project; Notice of Preliminary Permit Application Accepted for Filing and...

    Science.gov (United States)

    2012-01-27

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Project No. 13089-002] Conway Ranch Hydropower Project; Notice of Preliminary Permit Application Accepted for Filing and Soliciting Comments... study the feasibility of the Conway Ranch Hydropower Project to be located on Virginia Creek, near the...

  16. 76 FR 9340 - Mill Town Power Project; Notice of Preliminary Permit Application Accepted for Filing and...

    Science.gov (United States)

    2011-02-17

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Project No. 13995-000] Mill Town Power Project; Notice of Preliminary Permit Application Accepted for Filing and Soliciting Comments, Motions To Intervene, and Competing Applications On January 4, 2011, Mill Town Power Project filed an application for a...

  17. 76 FR 75543 - Castle Creek Hydroelectric Project; Notice of Preliminary Permit Application Accepted for Filing...

    Science.gov (United States)

    2011-12-02

    ... Hydroelectric Project; Notice of Preliminary Permit Application Accepted for Filing and Soliciting Comments... (FPA), proposing to study the feasibility of the Castle Creek Hydroelectric Project to be located on... be located adjacent to the original hydroelectric plant, with a single shaft Pelton turbine...

  18. 75 FR 61479 - Kendall Head Tidal Energy Project; Notice of Preliminary Permit Application Accepted for Filing...

    Science.gov (United States)

    2010-10-05

    ... Tidal Energy Project; Notice of Preliminary Permit Application Accepted for Filing and Soliciting... Federal Power Act, proposing to study the feasibility of the Kendall Head Tidal Energy Project, located in.... The proposed project would consist of: (1) 4 OCGen\\TM\\ hydrokinetic tidal devices each consisting of...

  19. Interaction between Na-K-ATPase and Bcl-2 proteins BclXL and Bak.

    Science.gov (United States)

    Lauf, Peter K; Alqahtani, Tariq; Flues, Karin; Meller, Jaroslaw; Adragna, Norma C

    2015-01-01

    In silico analysis predicts interaction between Na-K-ATPase (NKA) and Bcl-2 protein canonical BH3- and BH1-like motifs, consistent with NKA inhibition by the benzo-phenanthridine alkaloid chelerythrine, a BH3 mimetic, in fetal human lens epithelial cells (FHLCs) (Lauf PK, Heiny J, Meller J, Lepera MA, Koikov L, Alter GM, Brown TL, Adragna NC. Cell Physiol Biochem 31: 257-276, 2013). This report establishes proof of concept: coimmunoprecipitation and immunocolocalization showed unequivocal and direct physical interaction between NKA and Bcl-2 proteins. Specifically, NKA antibodies (ABs) coimmunoprecipitated BclXL (B-cell lymphoma extra large) and BAK (Bcl-2 antagonist killer) proteins in FHLCs and A549 lung cancer cells. In contrast, both anti-Bcl-2 ABs failed to pull down NKA. Notably, the molecular mass of BAK1 proteins pulled down by NKA and BclXL ABs appeared to be some 4-kDa larger than found in input monomers. In silico analysis predicts these higher molecular mass BAK1 proteins as alternative splicing variants, encoding 42 amino acid (aa) larger proteins than the known 211-aa long canonical BAK1 protein. These BAK1 variants may constitute a pool separate from that forming mitochondrial pores by specifically interacting with NKA and BclXL proteins. We propose a NKA-Bcl-2 protein ternary complex supporting our hypothesis for a special sensor role of NKA in Bcl-2 protein control of cell survival and apoptosis. Copyright © 2015 the American Physiological Society.

  20. Mountaineer Commercial Scale Carbon Capture and Storage Project Topical Report: Preliminary Public Design Report

    Energy Technology Data Exchange (ETDEWEB)

    Guy Cerimele

    2011-09-30

    This Preliminary Public Design Report consolidates for public use nonproprietary design information on the Mountaineer Commercial Scale Carbon Capture & Storage project. The report is based on the preliminary design information developed during the Phase I - Project Definition Phase, spanning the time period of February 1, 2010 through September 30, 2011. The report includes descriptions and/or discussions for: (1) DOE's Clean Coal Power Initiative, overall project & Phase I objectives, and the historical evolution of DOE and American Electric Power (AEP) sponsored projects leading to the current project; (2) Alstom's Chilled Ammonia Process (CAP) carbon capture retrofit technology and the carbon storage and monitoring system; (3) AEP's retrofit approach in terms of plant operational and integration philosophy; (4) The process island equipment and balance of plant systems for the CAP technology; (5) The carbon storage system, addressing injection wells, monitoring wells, system monitoring and controls logic philosophy; (6) Overall project estimate that includes the overnight cost estimate, cost escalation for future year expenditures, and major project risks that factored into the development of the risk based contingency; and (7) AEP's decision to suspend further work on the project at the end of Phase I, notwithstanding its assessment that the Alstom CAP technology is ready for commercial demonstration at the intended scale.

  1. What history tells us XL. The success story of the expression ...

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences; Volume 41; Issue 1. What history tells us XL. The success story of the expression 'genome editing'. Michel Morange. Series Volume 41 Issue 1 March 2016 pp 9-11. Fulltext. Click here to view fulltext PDF. Permanent link: https://www.ias.ac.in/article/fulltext/jbsc/041/01/0009-0011 ...

  2. LANSCE Beam Current Limiter (XL)

    International Nuclear Information System (INIS)

    Gallegos, F.R.; Hall, M.J.

    1997-01-01

    The Radiation Security System (RSS) at the Los Alamos Neutron Science Center (LANSCE) is an engineered safety system that provides personnel protection from prompt radiation due to accelerated proton beams. The Beam Current Limiter (XL), as an active component of the RSS, limits the maximum average current in a beamline, thus the current available for a beam spill accident. Exceeding the pre-set limit initiates action by the RSS to mitigate the hazard (insertion of beam stoppers in the low energy beam transport). The beam limiter is an electrically isolated, toroidal transformer and associated electronics. The device was designed to continuously monitor beamline currents independent of any external timing. Fail-safe operation was a prime consideration in its development. Fail-safe operation is defined as functioning as intended (due to redundant circuitry), functioning with a more sensitive fault threshold, or generating a fault condition. This report describes the design philosophy, hardware, implementation, operation, and limitations of the device

  3. Point Climat no. 30 'Seeing the forest from the trees: Infrastructure Investment and 'systemic' GHG impacts - Lessons from the Keystone XL'

    International Nuclear Information System (INIS)

    Cochran, Ian; Morel, Romain

    2013-01-01

    Among the publications of CDC Climat Research, 'Climate Briefs' presents, in a few pages, hot topics in climate change policy. This issue addresses the following points: - Achieving the 'energy transition', it is necessary to ask how individual investments support or hinder progress towards a low-carbon, energy-efficient future. This requires a a systemic approach - or 'scope 4' analysis. - As demonstrated by the Keystone XL Oil pipeline project in North America, even when individual pieces of infrastructure emit relatively low levels of direct greenhouse gases, they can foster the continuation of system that will continue to favor, and financially reward, investments supporting a fossil fuel-based economy. - Effectively addressing greenhouse gas emissions and fully understanding the impact of individual projects - both as individual elements and lynch pins of a larger system - will require a wider scope of integration into both project development and financial decision making than currently occurs

  4. 78 FR 49509 - Lock+ Hydro Friends Fund XXX, LLC; FFP Project 121, LLC; Notice Announcing Preliminary Permit...

    Science.gov (United States)

    2013-08-14

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [ Project No. 13625-003; Project No. 14504-000] Lock+ Hydro Friends Fund XXX, LLC; FFP Project 121, LLC; Notice Announcing Preliminary Permit... and Jefferson County, Ohio. The applications were filed by Lock+ Hydro Friends Fund XXX, LLC for...

  5. 77 FR 60424 - FFP Project 73 LLC; Notice of Preliminary Permit Application Accepted for Filing and Soliciting...

    Science.gov (United States)

    2012-10-03

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Project No. 13484-001] FFP Project 73 LLC; Notice of Preliminary Permit Application Accepted for Filing and Soliciting Comments, Motions To Intervene, and Competing Applications On September 4, 2012, FFP Project 73, LLC filed an application for a...

  6. Removal of copper (II) from aqueous solutions by flotation using polyaluminum chloride silicate (PAX-XL60 S) as coagulant and carbonate ion as activator.

    Science.gov (United States)

    Ghazy, S E; Mahmoud, I A; Ragab, A H

    2006-01-01

    Flotation is a separation technology for removing toxic heavy metal ions from aqueous solutions. Here a simple and rapid flotation procedure is presented for the removal of copper(II) from aqueous solutions. It is based on the use of polyaluminum chloride silicate (PAX-XL60 S) as coagulant and flocculent, carbonate ion as activator and oleic acid (HOL) as surfactant. Both ion and precipitate flotation are included depending on the solution pH. Ion and precipitate flotation in the aqueous HOL-PAX-XL60 S-Cu2+-CO3(2-) system gave powerful preferential removal of Cu2+ (F -100%) over the HOL-PAX-XL60 S-Cu2+ system containing no CO3(2+) ion (F approximately 86%). The role of CO3(2-) ion is also evident from decreasing the dose of PAX-XL60 S from 700 mg l(-1) to 200 mg l(-1). The other parameters, influencing the flotation process, namely: metal ion, surfactant and PAX-XL60 S concentrations, ionic strength, temperature and foreign ions were examined. Moreover, the procedure was successfully applied to recover Cu2+ ions from different volumes up to 11 and from natural water samples.

  7. Ambient Assisted Living and ageing: preliminary results of RITA project.

    Science.gov (United States)

    Aquilano, Michela; Cavallo, Filippo; Bonaccorsi, Manuele; Esposito, Raffaele; Rovini, Erika; Filippi, Massimo; Esposito, Dario; Dario, Paolo; Carrozza, Maria Chiara

    2012-01-01

    The ageing of population is a social phenomenon that most of worldwide countries are facing. They are, and will be even more in the future, indeed trying to find solutions for improving quality of life of their elderly citizens. The project RITA wants to demonstrate that an update of the current socio-medical services with an Ambient Assisted Living (AAL) approach could improve the service efficiency and the quality of life of both elderly and caregiver. This paper presents the preliminary results obtained in RITA.

  8. Project Rulison: A preliminary report

    Energy Technology Data Exchange (ETDEWEB)

    Reynolds, Miles Jr [Austral Oil Company Incorporated, Houston, TX (United States); Bray, Bruce G; Mann, Robert L [CER Geonuclear Corporation, Las Vegas, NV (United States)

    1970-05-01

    Project Rulison was designed to use underground nuclear technology to determine the potential of this technique for commercial development of the deep, thick, lenticular, low permeability, Mesaverde Formation of the Rulison Field in Garfield County, Colorado. Since discovery in 1952, this reservoir has been tested by nine widely-spaced conventionally completed wells. A method of stimulation, far greater in magnitude and efficiency than conventional hydraulic fracturing, is needed to recover this gas at economic rates. A feasibility study completed in July 1966 indicated that nuclear explosives were a potentially economic method of stimulating recovery of natural gas from the reservoir. The gas-in-place, estimated to be between 90-125 billion cubic feet per 640 acres from earlier wells, was confirmed from information obtained on two conventional wells completed in 1966. The Project Rulison exploratory well, R-EX, was completed in May 1968. Detailed testing of this well provided data on geology, hydrology and reservoir characteristics. The data obtained from the testing have been used to determine the flow capacity of the Mesaverde reservoir. The reservoir characteristics were then used as input data to make predictions of post-shot reservoir performance in the nuclear stimulated well, using a radial, unsteady state gas flow computer model. A nuclear explosive with a design yield of 40 kilotons was emplaced in a 10-3/4 inch hole at a depth of 8426 feet below ground surface and detonated on September 10, 1969. A preliminary appraisal of the data taken at shot time indicate that the explosive behaved as predicted. The explosion was completely contained underground as predicted and no major seismic damage occurred. The post-shot drilling program, to reenter the chimney, will congruence in March 1970, approximately six months after detonation. A test program will be initiated at that time to determine the degree of reservoir stimulation achieved. (author)

  9. Preliminary corrosion models for BWIP [Basalt Waste Isolation Project] canister materials

    International Nuclear Information System (INIS)

    Fish, R.L.; Anantatmula, R.P.

    1983-01-01

    Waste package development for the Basalt Waste Isolation Project (BWIP) requires the generation of materials degradation data under repository relevant conditions. These data are used to develop predictive models for the behavior of each component of waste package. The component models are exercised in performance analyses to optimize the waste package design. This document presents all repository relevant canister materials corrosion data that the BWIP and others have developed to date, describes the methodology used to develop preliminary corrosion models and provides the mathematical description of the models for both low carbon steel and Fe9Cr1Mo steel. Example environment/temperature history and model application calculations are presented to aid in understanding the models. The models are preliminary in nature and will be updated as additional corrosion data become available. 6 refs., 5 tabs

  10. Whole Module Offgas Test Report: Space-Xl Dragon Module

    Science.gov (United States)

    James, John T.

    2012-01-01

    On September 26 and September 28,2012 a chemist from the JSC Toxicology Group acquired samples of air in 500 m1 evacuated canisters from the sealed Space-Xl Dragon Module. One sample was also acquired from Space-X Facility near the module at the start of the test. Samples of the module air were taken in triplicate once the module had been sealed, and then taken again in triplicate 1.98 days later. Ofthe triplicate samples, the first served as a line purge, and the last two were analyzed. The results of 5 samples are reported.

  11. Preliminary design report: Prototypical Spent Fuel Consolidation Equipment Demonstration Project: Phase 1

    International Nuclear Information System (INIS)

    Blissell, W.H.; Ciez, A.P.; Mitchell, J.L.; Winkler, C.J.

    1986-12-01

    This document describes the Westinghouse Preliminary Design for the Prototypical Consolidation Demonstration Project per Department of Energy (DOE) Contract No. DE-AC07-86ID12649 and under direction of the DOE Idaho Operations Office. The preliminary design is the first step to providing the Department of Energy with a fully qualified, licensable, cost-effective spent fuel rod consolidation system. The design was developed using proven technologies and equipment to create an innovative approach to previous rod consolidation concepts. These innovations will better enable the Westinghouse system to: consolidate fuel rods in a precise, fully-controlled, accountable manner; package all rods from two PWR fuel assemblies or from four BWR fuel assemblies in one 8.5 inch square consolidated rods canister; meet all functional requirements; operate with all fuel types common to the US commercial nuclear industry with minimal tooling changeouts; and meet consolidation production process rates, while maintaining operator and public health and safety. This Preliminary Design Report provides both detailed descriptions of the equipment required to perform the rod consolidation process and the supporting analyses to validate the design

  12. [A comparison of rebound tonometry (ICare) with TonoPenXL and Goldmann applanation tonometry].

    Science.gov (United States)

    Schreiber, W; Vorwerk, C K; Langenbucher, A; Behrens-Baumann, W; Viestenz, A

    2007-04-01

    Goldmann applanation tonometry and dynamic contour tonometry (PASCAL) are two well established slit lamp mounted tonometric methods. Intraocular pressure measurement in bedridden patients and children is often only possible using hand held tonometers (TonoPenXL, Perkins tonometer, Draeger tonometer). This study was performed to evaluate the hand held ICare tonometer, which is based on the rebound method. A total of 102 eyes were examined by two highly experienced ophthalmologists for: 1) ophthalmological status, 2) central corneal power (Zeiss IOL-Master), 3) central corneal thickness (Tomey ultrasound pachymetry, five successive measurements, SDr=0.592-0.642; p<0.001). There was a great intra-individual variability of up to 17 mmHg between the GAT, TonoPenXL and ICare methods. The ICare tonometer is easy to handle and high reliability. The data are comparable with those from the Goldmann tonometer. A tonography effect of 0.6 mmHg in the successive measurement series was found.

  13. Measurements of intraocular pressure by Goldmann tonometry, Tonopen XL, and the transpalpebral tonometer, TGDc-01, after penetrating keratoplasty: a comparativye study.

    Science.gov (United States)

    Shemesh, Gabi; Waisbourd, Michael; Varssano, David; Michaeli, Adi; Lazar, Moshe; Kurtz, Shimon

    2009-08-01

    The aim of this study was to compare intraocular pressure (IOP) measurements obtained by Goldmann tonometry (GT), the Tonopen XL, and a new transpalpebral tonometer, TGDc-01, in eyes that had undergone penetrating keratoplasty (PKP). IOP was measured in post-PKP eyes by means of GT, Tonopen XL, and TGDc-01. Central corneal thickness measurements were also obtained for all eyes. Forty-five eyes of 43 patients were enrolled in the study. The mean IOP difference (+/-SD) was -0.42 +/- 5.83 mm Hg between GT and Tonopen and 3.20 +/- 7.55 mm Hg between GT and TGDc-01. The correlation coefficient was 0.84 between GT and Tonopen XL (P tonometer is simply inaccurate or whether avoiding contact with the corneal graft by measuring IOP through the eyelid enables it to provide more accurate IOP readings than those obtained by transcorneal techniques.

  14. Suggestions and comments about preliminary plans of ABNT 20:04.002-001 standard 'Seismic actions for nuclear facilities project'

    International Nuclear Information System (INIS)

    Soares, W.A.

    1984-01-01

    This paper presents an analysis of preliminary plans of standard 'seismic actions for nuclear facilities project'. This document presents since seismic event characterization up to details of structural project of nuclear facilities construction. (C.M.)

  15. Clinical significance of proliferation, apoptosis and senescence of nasopharyngeal cells by the simultaneously blocking EGF, IGF-1 receptors and Bcl-xl genes

    International Nuclear Information System (INIS)

    Dai, Guodong; Peng, Tao; Zhou, Xuhong; Zhu, Jun; Kong, Zhihua; Ma, Li; Xiong, Zhi; Yuan, Yulin

    2013-01-01

    Highlight: •Construction of shRNA segments expression vectors is valid by the investigation of RT-PCR for IGF1R, EGFR and Bcl-xl mRNA and protein expression. •Studies have suggested that the vectors in blocking these genes of the growth factor receptors and anti- apoptosis is capable of breaking the balance of tumor growth so that tumor trend apoptosis and senescence. •Simultaneously blocking multiple genes that are abnormally expressed may be more effective in treating cancer cells than silencing a single gene. -- Abstract: Background: In previous work, we constructed short hairpin RNA (shRNA) expression plasmids that targeted human EGF and IGF-1 receptors messenger RNA, respectively, and demonstrated that these vectors could induce apoptosis of human nasopharyngeal cell lines (CNE2) and inhibit ligand-induced pAkt and pErk activation. Method: We have constructed multiple shRNA expression vectors of targeting EGFR, IGF1R and Bcl-xl, which were transfected to the CNE2 cells. The mRNA expression was assessed by RT-PCR. The growth of the cells, cell cycle progression, apoptosis of the cells, senescent tumor cells and the proteins of EGFR, IGF1R and Bcl-xl were analyzed by MTT, flow cytometry, cytochemical therapy or Western blot. Results: In group of simultaneously blocking EGFR, IGF1R and Bcl-xl genes, the mRNA of EGFR, IGF1R and Bcl-xl expression was decreased by (66.66 ± 3.42)%, (73.97 ± 2.83)% and (64.79 ± 2.83)%, and the protein expressions was diminished to (67.69 ± 4.02)%, (74.32 ± 2.30)%, and (60.00 ± 3.34)%, respectively. Meanwhile, the cell apoptosis increased by 65.32 ± 0.18%, 65.16 ± 0.25% and 55.47 ± 0.45%, and senescent cells increased by 1.42 ± 0.15%, 2.26 ± 0.15% and 3.22 ± 0.15% in the second, third and fourth day cultures, respectively. Conclusions: Simultaneously blocking EGFR, IGF1R and Bcl-xl genes is capable of altering the balance between proliferating versus apoptotic and senescent cells in the favor of both of apoptosis and

  16. Clinical significance of proliferation, apoptosis and senescence of nasopharyngeal cells by the simultaneously blocking EGF, IGF-1 receptors and Bcl-xl genes

    Energy Technology Data Exchange (ETDEWEB)

    Dai, Guodong [Anatomy and Embryology, Wuhan University School of Medicine, Wuhan, Hubei 430071 (China); Peng, Tao; Zhou, Xuhong [Department of Otolaryngology-Head and Neck Surgery, Zhongnan Hospital of Wuhan University, Wuhan 430071 (China); Zhu, Jun; Kong, Zhihua; Ma, Li; Xiong, Zhi [Anatomy and Embryology, Wuhan University School of Medicine, Wuhan, Hubei 430071 (China); Yuan, Yulin, E-mail: yuanyulin19620120@126.com [Anatomy and Embryology, Wuhan University School of Medicine, Wuhan, Hubei 430071 (China)

    2013-11-01

    Highlight: •Construction of shRNA segments expression vectors is valid by the investigation of RT-PCR for IGF1R, EGFR and Bcl-xl mRNA and protein expression. •Studies have suggested that the vectors in blocking these genes of the growth factor receptors and anti- apoptosis is capable of breaking the balance of tumor growth so that tumor trend apoptosis and senescence. •Simultaneously blocking multiple genes that are abnormally expressed may be more effective in treating cancer cells than silencing a single gene. -- Abstract: Background: In previous work, we constructed short hairpin RNA (shRNA) expression plasmids that targeted human EGF and IGF-1 receptors messenger RNA, respectively, and demonstrated that these vectors could induce apoptosis of human nasopharyngeal cell lines (CNE2) and inhibit ligand-induced pAkt and pErk activation. Method: We have constructed multiple shRNA expression vectors of targeting EGFR, IGF1R and Bcl-xl, which were transfected to the CNE2 cells. The mRNA expression was assessed by RT-PCR. The growth of the cells, cell cycle progression, apoptosis of the cells, senescent tumor cells and the proteins of EGFR, IGF1R and Bcl-xl were analyzed by MTT, flow cytometry, cytochemical therapy or Western blot. Results: In group of simultaneously blocking EGFR, IGF1R and Bcl-xl genes, the mRNA of EGFR, IGF1R and Bcl-xl expression was decreased by (66.66 ± 3.42)%, (73.97 ± 2.83)% and (64.79 ± 2.83)%, and the protein expressions was diminished to (67.69 ± 4.02)%, (74.32 ± 2.30)%, and (60.00 ± 3.34)%, respectively. Meanwhile, the cell apoptosis increased by 65.32 ± 0.18%, 65.16 ± 0.25% and 55.47 ± 0.45%, and senescent cells increased by 1.42 ± 0.15%, 2.26 ± 0.15% and 3.22 ± 0.15% in the second, third and fourth day cultures, respectively. Conclusions: Simultaneously blocking EGFR, IGF1R and Bcl-xl genes is capable of altering the balance between proliferating versus apoptotic and senescent cells in the favor of both of apoptosis and

  17. 4MOST: the 4-metre Multi-Object Spectroscopic Telescope project at preliminary design review

    NARCIS (Netherlands)

    de Jong, Roelof S.; Barden, Samuel C.; Bellido-Tirado, Olga; Brynnel, Joar G.; Frey, Steffen; Giannone, Domenico; Haynes, Roger; Johl, Diana; Phillips, Daniel; Schnurr, Olivier; Walcher, Jakob C.; Winkler, Roland; Ansorge, Wolfgang R.; Feltzing, Sofia; McMahon, Richard G.; Baker, Gabriella; Caillier, Patrick; Dwelly, Tom; Gaessler, Wolfgang; Iwert, Olaf; Mandel, Holger G.; Piskunov, Nikolai A.; Pragt, Johan H.; Walton, Nicholas A.; Bensby, Thomas; Bergemann, Maria; Chiappini, Cristina; Christlieb, Norbert; Cioni, Maria-Rosa L.; Driver, Simon; Finoguenov, Alexis; Helmi, Amina; Irwin, Michael J.; Kitaura, Francisco-Shu; Kneib, Jean-Paul; Liske, Jochen; Merloni, Andrea; Minchev, Ivan; Richard, Johan; Starkenburg, Else

    2016-01-01

    We present an overview of the 4MOST project at the Preliminary Design Review. 4MOST is a major new wide-field, high-multiplex spectroscopic survey facility under development for the VISTA telescope of ESO. 4MOST has a broad range of science goals ranging from Galactic Archaeology and stellar physics

  18. A Microsoft-Excel-based tool for running and critically appraising network meta-analyses--an overview and application of NetMetaXL.

    Science.gov (United States)

    Brown, Stephen; Hutton, Brian; Clifford, Tammy; Coyle, Doug; Grima, Daniel; Wells, George; Cameron, Chris

    2014-09-29

    The use of network meta-analysis has increased dramatically in recent years. WinBUGS, a freely available Bayesian software package, has been the most widely used software package to conduct network meta-analyses. However, the learning curve for WinBUGS can be daunting, especially for new users. Furthermore, critical appraisal of network meta-analyses conducted in WinBUGS can be challenging given its limited data manipulation capabilities and the fact that generation of graphical output from network meta-analyses often relies on different software packages than the analyses themselves. We developed a freely available Microsoft-Excel-based tool called NetMetaXL, programmed in Visual Basic for Applications, which provides an interface for conducting a Bayesian network meta-analysis using WinBUGS from within Microsoft Excel. . This tool allows the user to easily prepare and enter data, set model assumptions, and run the network meta-analysis, with results being automatically displayed in an Excel spreadsheet. It also contains macros that use NetMetaXL's interface to generate evidence network diagrams, forest plots, league tables of pairwise comparisons, probability plots (rankograms), and inconsistency plots within Microsoft Excel. All figures generated are publication quality, thereby increasing the efficiency of knowledge transfer and manuscript preparation. We demonstrate the application of NetMetaXL using data from a network meta-analysis published previously which compares combined resynchronization and implantable defibrillator therapy in left ventricular dysfunction. We replicate results from the previous publication while demonstrating result summaries generated by the software. Use of the freely available NetMetaXL successfully demonstrated its ability to make running network meta-analyses more accessible to novice WinBUGS users by allowing analyses to be conducted entirely within Microsoft Excel. NetMetaXL also allows for more efficient and transparent

  19. Direct comparison of the FibroScan XL and M probes for assessment of liver fibrosis in obese and nonobese patients

    Directory of Open Access Journals (Sweden)

    Durango E

    2013-07-01

    Full Text Available Esteban Durango,1,* Christian Dietrich,1,* Helmut Karl Seitz,1 Cornelia Ursula Kunz,2 Gilles T Pomier-Layrargues,3 Andres Duarte-Rojo,4 Melanie Beaton,5 Magdy Elkhashab,6 Robert P Myers,7 Sebastian Mueller1,3 1Department of Medicine and Center for Alcohol Research, Liver Disease and Nutrition, Salem Medical Center, 2Institute of Medical Biometry and Informatics, University of Heidelberg, Heidelberg, Germany; 3Liver Unit, Centre Hospitalier de l'Université de Montréal, Hôpital Saint-Luc, Montréal, Quebec, 4Toronto Western Hospital Liver Centre, Toronto, Ontario; 5Multi-Organ Transplant Unit, University of Western Ontario, London, Ontario; 6The Toronto Liver Centre, Toronto, Ontario; 7Liver Unit, Division of Gastroenterology and Hepatology, Department of Medicine, University of Calgary, Calgary, Alberta, Canada *These authors contributed equally to this researchBackground: A novel Fibroscan XL probe has recently been introduced and validated for obese patients, and has a diagnostic accuracy comparable with that of the standard M probe. The aim of this study was to analyze and understand the differences between these two probes in nonobese patients, to identify underlying causes for these differences, and to develop a practical algorithm to translate results for the XL probe to those for the M probe.Methods and results: Both probes were directly compared first in copolymer phantoms of varying stiffness (4.8, 11, and 40 kPa and then in 371 obese and nonobese patients (body mass index, range 17.2–72.4 from German (n = 129 and Canadian (n = 242 centers. Liver stiffness values for both probes correlated better in phantoms than in patients (r = 0.98 versus 0.82, P 10 kPa for F0, F1–2, F3, and F4 fibrosis, respectively significantly improved agreement between the two probes from r = 0.655 to 0.679.Conclusion: Liver stiffness can be measured in significantly more obese and nonobese patients using the XL probe than the M probe. However, the XL

  20. Preliminary results on the cryogenic target for FIREX project

    International Nuclear Information System (INIS)

    Iwamoto, A.; Maekawa, R.; Mito, T.; Okamoto, M.; Motojima, O.; Nakai, M.; Norimatsu, T.; Nagai, K.

    2006-01-01

    Preliminary tests on the cryogenic target for the fast ignition realization experiment (FIREX) project has been conducted. A foam shell method is proposed to realize its target design. A foam target consists of three parts: a foam shell, a conical laser guide and a liquid or gas feeder made of glass. The shell is a hollow sphere (500 μm in diameter) with a uniform and thin foam layer (about 20 μm in thickness). Epoxy resin is utilized to assemble the parts into the target. Liquid fuel is fed into the shell by the feeder and is soaked up by the foam material through capillarity. The fuel is then solidified. Regarding target fabrication, one of the concerns is the influence on various thermal contractions from the different materials when it is cooled down to cryogenic environment. This paper describes the result on the validity check at cryogenic environment and the demonstration of H 2 liquefaction using a dummy target instead of the foam target. Judging from these results, the target assembled in the same process as the dummy target is sure to be practicable for the FIREX project. (authors)

  1. Can Bcl-XL expression predict the radio sensitivity of Bilharzial-related squamous bladder carcinoma? a prospective comparative study

    Directory of Open Access Journals (Sweden)

    Kamel Nermen A

    2011-01-01

    Full Text Available Abstract Background Local pelvic recurrence after radical cystectomy for muscle invasive bilharzial related squamous cell carcinoma accounts for 75% of treatment failures even in organ confined tumors. Despite the proven value of lymphadenectomy, up to 60% of patients undergoing cystectomy do not have it. These factors are in favor of adjuvant radiotherapy reevaluation. objectives: to evaluate the effect of adjuvant radiotherapy on disease free survival in muscle invasive bilharzial related squamous cell carcinoma of the urinary bladder and to test the predictability of radio-sensitivity using the anti apoptotic protein Bcl-XL. Methods The study prospectively included 71 patients, (47 males, 24 females with muscle invasive bilharzial related squamous cell carcinoma of the bladder (Stage pT2a-T3N0-N3M0 who underwent radical cystectomy in Assiut university hospitals between January 2005 and December 2006. Thirty eight patients received adjuvant radiotherapy to the pelvis in the dose of 50Gy/25 fractions/5 weeks (Group 1, while 33 patients did not receive adjuvant radiotherapy (group 2. Immunohistochemical characterization for bcl-xL expression was done. Follow up was done every 3 months for 12 to 36 months with a mean of 16 ± 10 months. All data were analyzed using SPSS version 16. Three years cumulative disease free survival was calculated and adjusted to Bcl-XL expression and side effects of the treatment were recorded. Results The disease free cumulative survival was 48% for group 1 and 29% for group 2 (log rank p value 0.03. The multivariate predictors of tumor recurrence were the positive Bcl-XL expression (odd ratio 41.1, 95% CI 8.4 - 102.3, p Conclusions Adjuvant radiotherapy for muscle invasive bilharzial related squamous cell carcinoma of the urinary bladder has potential effectiveness and minor side effects. Moreover, Bcl-XL expression is a valuable tool for predicting those who might not respond to this adjuvant treatment.

  2. Butyrate down regulates BCL-XL and sensitizes human fibroblasts to radiation and chemotherapy induced apoptosis

    International Nuclear Information System (INIS)

    Chung, Diana H.; Ljungman, Mats; Zhang Fenfen; Chen Feng; McLaughlin, William P.

    1997-01-01

    Purpose/Objective: Butyrate is a short chain fatty acid that has been implicated in the induction of cell cycle arrest, cell differentiation and apoptosis. The purpose of this study was to determine if butyrate treatment sensitizes cells to radiation or chemotherapy induced apoptosis. Materials and Methods: Normal neonatal human diploid fibroblasts were used throughout this study. Apoptosis was scored and quantified using three different methods. First, cell morphology using propidium iodide and fluorescence microscopy was used to qualitatively determine apoptosis and to quantify the percentage of cells undergoing apoptosis. Second, apoptosis induced DNA degradation was scored by quantifying the amount of cells appearing in a sub-G1 peak using fixed and PI-stained cells and flow cytometry. Third, apoptosis-induced DNA degradation was examined by using an assay involving direct lysis of cells in the wells of agarose gels followed by conventional gel electrophoresis. Western blotting was used to quantify the cellular levels of the apoptosis regulators, Bcl-2, Bcl-XL and Bax. Results: Human diploid fibroblasts, which were resistant to radiation induced apoptosis, were found to undergo massive apoptosis when radiation was combined with butyrate treatment. Sensitization was obtained when butyrate was added before or after radiation although the combination of both pre and post-treatment was the most effective. Butyrate was also found to enhance UV light and cisplatin-induced apoptosis. These findings correlated with a reduction of the apoptosis antagonist Bcl-XL. Bcl-XL levels significantly dropped in a time and dose dependent manner. In addition, butyrate effectively blocked UV-induced accumulation of p53. Conclusion: Our results suggest that butyrate may be an attractive agent to use in combination with radiation or chemotherapy to lower the apoptotic threshold of tumor cells, regardless of the p53 status of the tumor cells

  3. Indications for MARS-MRI in Patients Treated With Articular Surface Replacement XL Total Hip Arthroplasty.

    Science.gov (United States)

    Connelly, James W; Galea, Vincent P; Laaksonen, Inari; Matuszak, Sean J; Madanat, Rami; Muratoglu, Orhun; Malchau, Henrik

    2018-04-19

    The purpose of this study was to identify which patient and clinical factors are predictive of adverse local tissue reaction (ALTR) and to use these factors to create a highly sensitive algorithm for indicating metal artifact reduction sequence magnetic resonance imaging (MARS-MRI) in Articular Surface Replacement (ASR) XL total hip arthroplasty patients. Our secondary aim was to compare our algorithm to existing national guidelines on when to take MARS-MRI in metal-on-metal total hip arthroplasty patients. The study consisted of 137 patients treated with unilateral ASR XL implants from a prospective, multicenter study. Patients underwent MARS-MRI regardless of clinical presentation at a mean of 6.2 (range, 3.3-10.4) years from surgery. Univariate and multivariate analyses were conducted to determine which variables were predictive of ALTR. Predictors were used to create an algorithm to indicate MARS-MRI. Finally, we compared our algorithm's ability to detect ALTR to existing guidelines. We found a visual analog scale pain score ≥2 (odds ratio [OR] = 2.53; P = .023), high blood cobalt (OR = 1.05; P = .023), and male gender (OR = 2.37; P = .034) to be significant predictors of ALTR presence in our cohort. The resultant algorithm achieved 86.4% sensitivity and 60.2% specificity in detecting ALTR within our cohort. Our algorithm had the highest area under the curve and was the only guideline that was significantly predictive of ALTR (P = .014). Our algorithm including patient-reported pain and sex-specific cutoffs for blood cobalt levels could predict ALTR and indicate MARS-MRI in our cohort of ASR XL metal-on-metal patients with high sensitivity. Level II, diagnostic study. Copyright © 2018 Elsevier Inc. All rights reserved.

  4. A preliminary social and economic assessment of the Basalt Waste Isolation Project

    International Nuclear Information System (INIS)

    Cluett, C.; Bolton, P.; York, K.; Wood, M.; Radford, L.

    1981-07-01

    This report provides a preliminary assessment of the social and economic impacts that could be caused by the construction and operation of a nuclear waste repository on the Hanford Site near Richland, Washington. This assessment involved assembling a comprehensive data base for the local Tri-Cities impact area and the surrounding region, establishing a network of local and regional contacts, making preliminary judgments about potential social impacts caused by the proposed repository, and recommending further research. This report concludes that growth effects under the anticipated work force scenario are expected to be relatively minor. With a strong public involvement program on the part of the project developers, including an ongoing dialogue with local and regional planners, potential socio-economic impacts can be anticipated and managed effectively. Specific recommendations are made for filling gaps in the available data, exploring key issues in more detail, and improving the analysis of social impacts. The report was prepared by the Battelle-Human Affairs Research Center in 1980 and 1981

  5. A New and Versatile Adjustable Rigidity Actuator with Add-on Locking Mechanism (ARES-XL

    Directory of Open Access Journals (Sweden)

    Manuel Cestari

    2018-01-01

    Full Text Available Adjustable compliant actuators are being designed and implemented in robotic devices because of their ability to minimize large forces due to impacts, to safely interact with the user, and to store and release energy in passive elastic elements. Conceived as a new force-controlled compliant actuator, an adjustable rigidity with embedded sensor and locking mechanism actuator (ARES-XL is presented in this paper. This compliant system is intended to be implemented in a gait exoskeleton for children with neuro muscular diseases (NMDs to exploit the intrinsic dynamics during locomotion. This paper describes the mechanics and initial evaluation of the ARES-XL, a novel variable impedance actuator (VIA that allows the implementation of an add-on locking mechanism to this system, and in combination with its zero stiffness capability and large deflection range, provides this novel joint with improved properties when compared to previous prototypes developed by the authors and other state-of-the-art (SoA devices. The evaluation of the system proves how this design exceeds the main capabilities of a previous prototype as well as providing versatile actuation that could lead to its implementation in multiple joints.

  6. Drinking-water hydropower installation at Schattdorf - Preliminary project; Trinkwasserkraftwerk Oberfeld Haldi bei Schattdorf. Programm Kleinwasserkraftwerke. Vorprojekt 2009

    Energy Technology Data Exchange (ETDEWEB)

    Gasser, M.

    2009-09-15

    This preliminary project report for the Swiss Federal Office of Energy (SFOE) describes the project for the construction of a small hydropower installation near Schattdorf, Switzerland. The location of the Faetsch springs and the ownership of the various land parcels involved are described. The general water supply project for Oberfeld-Haldi and the various springs and reservoirs involved are also discussed. The works necessary for the realisation of the hydropower project are described and discussed. Cost estimates are presented and the application for cost-covering remuneration of the scheme is noted. Estimates of energy production are presented and discussed, as is the economic viability of the project. Environmental aspects of the project are also discussed.

  7. Controlled attenuation parameter using the FibroScan® XL probe for quantification of hepatic steatosis for non-alcoholic fatty liver disease in an Asian population.

    Science.gov (United States)

    Chan, Wah-Kheong; Nik Mustapha, Nik Raihan; Wong, Grace Lai-Hung; Wong, Vincent Wai-Sun; Mahadeva, Sanjiv

    2017-02-01

    The FibroScan® XL probe reduces failure of liver stiffness measurement (LSM) and unreliable results in obese patients. The objective of this article is to evaluate the accuracy of controlled attenuation parameter (CAP) obtained using the XL probe for the estimation of hepatic steatosis in patients with non-alcoholic fatty liver disease (NAFLD). Adult NAFLD patients with a liver biopsy within six months were included and were examined with the FibroScan® M and XL probes. Histopathological findings were reported according to the Non-Alcoholic Steatohepatitis Clinical Research Network Scoring System. Participants who did not have fatty liver on ultrasonography were recruited as controls. A total of 57 NAFLD patients and 22 controls were included. The mean age of the NAFLD patients and controls was 50.1 ± 10.4 years and 20.2 ± 1.3 years, respectively ( p  = 0.000). The mean body mass index was 30.2 ± 5.0 kg per m 2 and 20.5 ± 2.4 kg per m 2 , respectively ( p  = 0.000). The distribution of steatosis grades were: S0, 29%; S1, 17%; S2, 35%; S3, 19%. The AUROC for estimation of steatosis grade ≥ S1, S2 and S3 was 0.94, 0.80 and 0.69, respectively, using the M probe, and 0.97, 0.81 and 0.67, respectively, using the XL probe. CAP obtained using the XL probe had similar accuracy as the M probe for the estimation of hepatic steatosis in NAFLD patients.

  8. Preliminary safety evaluation for 241-C-106 waste retrieval, project W-320

    International Nuclear Information System (INIS)

    Conner, J.C.

    1994-01-01

    This document presents the Preliminary Safety Evaluation for Project W-320, Tank 241-C-106 Waste Retrieval Sluicing System (WRSS). The US DOE has been mandated to develop plans for response to safety issues associated with the waste storage tanks at the Hanford Site, and to report the progress of implementing those plans to Congress. The objectives of Project W-230 are to design, fabricate, develop, test, and operate a new retrieval system capable of removing a minimum of about 75% of the high-heat waste contained in C-106. It is anticipated that sluicing operations can remove enough waste to reduce the remaining radiogenic heat load to levels low enough to resolve the high-heat safety issue as well as allow closure of the tank safety issue

  9. New construction of the Kelchbach hydropower installation - Preliminary project; Vorprojekt Neubau Kraftwerk Kelchbach. Programm Kleinwasserkraftwerke - Schlussbericht

    Energy Technology Data Exchange (ETDEWEB)

    Kalbermatten, J.

    2009-09-15

    This final report for the Swiss Federal Office of Energy (SFOE) describes the preliminary project for the new construction of a small hydropower installation on the Kelchbach stream in Naters, Switzerland. After a pressure-pipe rupture, the old, over 100 year-old installation was closed down. The replacement installation is planned to increase power production. The works necessary for the realisation of this hydropower project are described and discussed. Several older studies on the replacement of the installation are listed. Three variants are presented and discussed as are hydrological data on the project. Cost estimates are presented and discussed. Estimates of energy production are also presented and discussed, as is the economic viability of the project. Environmental aspects of the project are also examined.

  10. Behavior of solvent-exposed hydrophobic groove in the anti-apoptotic Bcl-XL protein: clues for its ability to bind diverse BH3 ligands from MD simulations.

    Directory of Open Access Journals (Sweden)

    Dilraj Lama

    Full Text Available Bcl-XL is a member of Bcl-2 family of proteins involved in the regulation of intrinsic pathway of apoptosis. Its overexpression in many human cancers makes it an important target for anti-cancer drugs. Bcl-XL interacts with the BH3 domain of several pro-apoptotic Bcl-2 partners. This helical bundle protein has a pronounced hydrophobic groove which acts as a binding region for the BH3 domains. Eight independent molecular dynamics simulations of the apo/holo forms of Bcl-XL were carried out to investigate the behavior of solvent-exposed hydrophobic groove. The simulations used either a twin-range cut-off or particle mesh Ewald (PME scheme to treat long-range interactions. Destabilization of the BH3 domain-containing helix H2 was observed in all four twin-range cut-off simulations. Most of the other major helices remained stable. The unwinding of H2 can be related to the ability of Bcl-XL to bind diverse BH3 ligands. The loss of helical character can also be linked to the formation of homo- or hetero-dimers in Bcl-2 proteins. Several experimental studies have suggested that exposure of BH3 domain is a crucial event before they form dimers. Thus unwinding of H2 seems to be functionally very important. The four PME simulations, however, revealed a stable helix H2. It is possible that the H2 unfolding might occur in PME simulations at longer time scales. Hydrophobic residues in the hydrophobic groove are involved in stable interactions among themselves. The solvent accessible surface areas of bulky hydrophobic residues in the groove are significantly buried by the loop LB connecting the helix H2 and subsequent helix. These observations help to understand how the hydrophobic patch in Bcl-XL remains stable in the solvent-exposed state. We suggest that both the destabilization of helix H2 and the conformational heterogeneity of loop LB are important factors for binding of diverse ligands in the hydrophobic groove of Bcl-XL.

  11. EUBerry: Competitiveness and marketing strategies of sustainable berries validated for improved health benefits - Introduction to the project and preliminary results

    NARCIS (Netherlands)

    Groot, M.J.; Roelofs, P.F.M.M.; Kaim, E.; Sijtsema, S.J.; Zimmermann, K.L.; Zmarlicki, K.

    2014-01-01

    The EUBerry project is not only building on technical research but also studies berry production and consumption from a social sciences perspective. This paper aims to describe the approach used in the EUBerry project about business economics as well as marketing. In addition some preliminary

  12. Comparison of the cardiovascular effects of tamsulosin oral controlled absorption system (OCAS) and alfuzosin prolonged release (XL)

    NARCIS (Netherlands)

    Michel, Martin C.; Chapple, Christopher R.

    2006-01-01

    OBJECTIVE: The cardiovascular (CV) effects of tamsulosin oral controlled absorption system (OCAS) 0.4 mg were compared with those of alfuzosin prolonged release (XL) 10 mg. METHODS: Two single-dose, crossover studies were performed. In study 1, CV alpha1-adrenoceptor antagonism was assessed by

  13. [Behavior in the forced-swimming test and expression of BDNF and Bcl-xl genes in the rat brain].

    Science.gov (United States)

    Berezova, I V; Shishkina, G T; Kalinina, T S; Dygalo, N N

    2011-01-01

    A single exposure of rats to the forced-swimming stress decreased BDNF mRNA levels in the cortex and increased Bcl-xl gene expression in the hippocampus and amygdala 24 h after the stress. The animals demonstrated a depressive-like behavior and elevated blood corticosterone level. There was a significant negative correlation between BDNF mRNA level in the cortex and immobility time during swimming. Repeated exposure to swimming stress caused the elevation of the hippocampal BDNF mRNA level assessed 24 h after the second swimming session. The data suggest that stress-induced down-regulation of cortical BDNF gene expression and behavioral despair in the forced-swimming test may be interrelated. The increase in the BDNF and Bcl-xl mRNA levels may contribute to the mechanisms protecting the brain against negative effects of stress.

  14. F-16XL Ship #2 Laminar Flow Glove mounting

    Science.gov (United States)

    1995-01-01

    NASA's two-seat F-16XL research aircraft is shown in the modification hangar at NASA's Dryden Flight Research Center, Edwards, California, during installation of a titanium 'glove' on the upper surface of its modified left wing. The aircraft subsequently carried out a 13-month-long, 45-flight research program which investigated drawing off a small part of the boundary-layer air in order to provide laminar--or smooth--flow over a major portion of a wing flying at supersonic speeds. A turbo-compressor in the aircraft's fuselage provided suction to draw air through more than 10 million tiny laser-drilled holes in the glove via a manifold system employing 20 valves. Data obtained during the program could assist designers of future aircraft in developing a more efficient high-speed civil transport.

  15. Site 300 hazardous-waste-assessment project. Interim report: December 1981. Preliminary site reconnaissance and project work plan

    International Nuclear Information System (INIS)

    Raber, E.; Helm, D.; Carpenter, D.; Peifer, D.; Sweeney, J.

    1982-01-01

    This document was prepared to outline the scope and objectives of the Hazardous Waste Assessment Project (HWAP) at Site 300. This project was initiated in October, 1981, to investigate the existing solid waste landfills in an effort to satisfy regulatory guidelines and assess the potential for ground-water contamination. This involves a site-specific investigation (utilizing geology, hydrology, geophysics and geochemistry) with the goal of developing an effective ground-water quality monitoring network. Initial site reconnaissance work has begun and we report the results, to date, of our geologic hydrogeologic studies. All known solid waste disposal locations are underlain by rocks of either the Late Miocene Neroly Formation or the Cierbo Formation, both of which are dominantly sandstones interbedded with shale and claystone. The existence of a regional confined (artesian) aquifer, as well as a regional water-table aquifer is postulated for Site 300. Preliminary analysis has led to an understanding of directions and depths of regional ground-water flow

  16. Preliminary sensitivity analyses of corrosion models for BWIP [Basalt Waste Isolation Project] container materials

    International Nuclear Information System (INIS)

    Anantatmula, R.P.

    1984-01-01

    A preliminary sensitivity analysis was performed for the corrosion models developed for Basalt Waste Isolation Project container materials. The models describe corrosion behavior of the candidate container materials (low carbon steel and Fe9Cr1Mo), in various environments that are expected in the vicinity of the waste package, by separate equations. The present sensitivity analysis yields an uncertainty in total uniform corrosion on the basis of assumed uncertainties in the parameters comprising the corrosion equations. Based on the sample scenario and the preliminary corrosion models, the uncertainty in total uniform corrosion of low carbon steel and Fe9Cr1Mo for the 1000 yr containment period are 20% and 15%, respectively. For containment periods ≥ 1000 yr, the uncertainty in corrosion during the post-closure aqueous periods controls the uncertainty in total uniform corrosion for both low carbon steel and Fe9Cr1Mo. The key parameters controlling the corrosion behavior of candidate container materials are temperature, radiation, groundwater species, etc. Tests are planned in the Basalt Waste Isolation Project containment materials test program to determine in detail the sensitivity of corrosion to these parameters. We also plan to expand the sensitivity analysis to include sensitivity coefficients and other parameters in future studies. 6 refs., 3 figs., 9 tabs

  17. De vis wordt duur(zaam) vervoerd : Openbare eindrapportage AKK-project ACD-03.032

    NARCIS (Netherlands)

    Snels, J.C.M.A.

    2005-01-01

    The project `De vis wordt duur(zaam) vervoerd` focuses on the reduction of the amount of driven kilometres in de supply from producers (i.e. Prime Meat and Seafood Partners) to the wholesaler and the distribution routes of the wholesaler (i.e. Deli XL).The reduction can be reached through (1)

  18. Preliminary selection criteria for the Yucca Mountain Project waste package container material

    International Nuclear Information System (INIS)

    Halsey, W.G.

    1991-01-01

    The Department of Energy's Yucca Mountain Project (YMP) is evaluating a site at Yucca Mountain in Nevada for construction of a geologic repository for the storage of high-level nuclear waste. Lawrence Livermore National Laboratory's (LLNL) Nuclear Waste Management Project (NWMP) has the responsibility for design, testing, and performance analysis of the waste packages. The design is performed in an iterative manner in three sequential phases (conceptual design, advanced conceptual design, and license application design). An important input to the start of the advanced conceptual design is the selection of the material for the waste containers. The container material is referred to as the 'metal barrier' portion of the waste package, and is the responsibility of the Metal Barrier Selection and Testing task at LLNL. The selection will consist of several steps. First, preliminary, material-independent selection criteria will be established based on the performance goals for the container. Second, a variety of engineering materials will be evaluated against these criteria in a screening process to identify candidate materials. Third, information will be obtained on the performance of the candidate materials, and final selection criteria and quantitative weighting factors will be established based on the waste package design requirements. Finally, the candidate materials will be ranked against these criteria to determine whether they meet the mandated performance requirements, and to provide a comparative score to choose the material for advanced conceptual design activities. This document sets forth the preliminary container material selection criteria to be used in screening candidate materials. 5 refs

  19. 77 FR 10740 - Riverbank Hydro No. 22, LLC; FFP Project 93, LLC; Notice Announcing Preliminary Permit Drawing

    Science.gov (United States)

    2012-02-23

    ...] Riverbank Hydro No. 22, LLC; FFP Project 93, LLC; Notice Announcing Preliminary Permit Drawing The..., will conduct a random drawing to determine the filing priority of the applicants identified in this... regulations.\\2\\ The priority established by this drawing will be used to determine which applicant, among...

  20. Sludge Treatment Project Engineered Container Retrieval And Transfer System Preliminary Design Hazard Analysis Supplement 1

    International Nuclear Information System (INIS)

    Franz, G.R.; Meichle, R.H.

    2011-01-01

    This 'What/If' Hazards Analysis addresses hazards affecting the Sludge Treatment Project Engineered Container Retrieval and Transfer System (ECRTS) NPH and external events at the preliminary design stage. In addition, the hazards of the operation sequence steps for the mechanical handling operations in preparation of Sludge Transport and Storage Container (STSC), disconnect STSC and prepare STSC and Sludge Transport System (STS) for shipping are addressed.

  1. 77 FR 9231 - Lock+ Hydro Friends Fund XXVIII; FFP Project 59, LLC; Notice Announcing Preliminary Permit Drawing

    Science.gov (United States)

    2012-02-16

    ...+ Hydro Friends Fund XXVIII; FFP Project 59, LLC; Notice Announcing Preliminary Permit Drawing The... of the Commission, or her designee, will conduct a random drawing to determine the filing priority of... applications as provided in section 4.37 of its regulations.\\2\\ The priority established by this drawing will...

  2. 77 FR 9230 - Lock+ Hydro Friends Fund XLV; FFP Project 2, LLC; Notice Announcing Preliminary Permit Drawing

    Science.gov (United States)

    2012-02-16

    ...+ Hydro Friends Fund XLV; FFP Project 2, LLC; Notice Announcing Preliminary Permit Drawing The Commission... her designee, will conduct a random drawing to determine the filing priority of the applicants... section 4.37 of its regulations.\\2\\ The priority established by this drawing will be used to determine...

  3. 77 FR 9230 - Lock+ Hydro Friends Fund XLIII; FFP Project 53, LLC; Notice Announcing Preliminary Permit Drawing

    Science.gov (United States)

    2012-02-16

    ...+ Hydro Friends Fund XLIII; FFP Project 53, LLC; Notice Announcing Preliminary Permit Drawing The... Commission, or her designee, will conduct a random drawing to determine the filing priority of the applicants... section 4.37 of its regulations.\\2\\ The priority established by this drawing will be used to determine...

  4. 77 FR 9232 - Lock+ Hydro Friends Fund XXXVIII; FFP Project 1, LLC; Notice Announcing Preliminary Permit Drawing

    Science.gov (United States)

    2012-02-16

    ...+ Hydro Friends Fund XXXVIII; FFP Project 1, LLC; Notice Announcing Preliminary Permit Drawing The..., or her designee, will conduct a random drawing to determine the filing priority of the applicants... section 4.37 of its regulations.\\2\\ The priority established by this drawing will be used to determine...

  5. 76 FR 55155 - Final Environmental Impact Statement for the Proposed Keystone XL Project

    Science.gov (United States)

    2011-09-06

    ... border of the U.S. and Canada for the transport of crude oil across the U.S./Canada international... proposed Project that is designed to transport crude oil produced from oil sands in the Western Canadian... security; environmental, cultural, and economic impacts. Before making a decision on the proposed Project...

  6. ACCI38 XL 2: a useful tool for dose assessment in case of accidental atmospheric releases of radionuclides

    International Nuclear Information System (INIS)

    Thomassin, A.; Merle-Szeremeta, A.

    2002-01-01

    In the scope of its assignments in the field of nuclear risks, the French Institute for Radiation protection and Nuclear Safety (IRSN) develops tools to assess the impact of nuclear facilities on their environment and surrounding populations. The code ACCI38 XL 2 is a tool dedicated to the assessment of integrated concentrations in the environment and of dosimetric consequences on man, in case of accidental atmospheric releases of radionuclides (up to 170 radionuclides). This code is widely used by IRSN for studies on accidents, mainly for the analysis of regulatory documents from nuclear operators. The aim of this communication is to present the main features of the model used in the code ACCI38 XL 2, and to give details about the code. After a general presentation of the model, a detailed description of atmospheric dispersion, transfer in the environment and radiological impact is given. Then, some information on parameters and limitations of the model and the code are presented

  7. 77 FR 9231 - Lock+ Hydro Friends Fund IV; FFP Project 55, LLC; Notice Announcing Preliminary Permit Drawing

    Science.gov (United States)

    2012-02-16

    ...+ Hydro Friends Fund IV; FFP Project 55, LLC; Notice Announcing Preliminary Permit Drawing The Commission... of the Commission, or her designee, will conduct a random drawing to determine the filing priority of... applications as provided in section 4.37 of its regulations.\\2\\ The priority established by this drawing will...

  8. Landscape ecological impact of climatic change some preliminary findings of the LICC Project

    International Nuclear Information System (INIS)

    Boer, M.M.

    1991-01-01

    The main objectives of the LICC project are to address the potential effects of a future climatic change on (semi-) natural terrestrial ecosystems and landscapes in Europe; six case studies are covered: alpine regions, boreal and subartic regions, Mediterranean region, fluvial systems, wetlands and coastal dunes. Preliminary findings showed a serious lack in fundamental ecological knowledge. Assessment of potential effects involved changes in water and sediment fluxes, changes in the vegetation cover, species response, dispersal and migration in a fragmented landscape and modification of climate impacts by man

  9. A Microsoft-Excel-based tool for running and critically appraising network meta-analyses—an overview and application of NetMetaXL

    Science.gov (United States)

    2014-01-01

    Background The use of network meta-analysis has increased dramatically in recent years. WinBUGS, a freely available Bayesian software package, has been the most widely used software package to conduct network meta-analyses. However, the learning curve for WinBUGS can be daunting, especially for new users. Furthermore, critical appraisal of network meta-analyses conducted in WinBUGS can be challenging given its limited data manipulation capabilities and the fact that generation of graphical output from network meta-analyses often relies on different software packages than the analyses themselves. Methods We developed a freely available Microsoft-Excel-based tool called NetMetaXL, programmed in Visual Basic for Applications, which provides an interface for conducting a Bayesian network meta-analysis using WinBUGS from within Microsoft Excel. . This tool allows the user to easily prepare and enter data, set model assumptions, and run the network meta-analysis, with results being automatically displayed in an Excel spreadsheet. It also contains macros that use NetMetaXL’s interface to generate evidence network diagrams, forest plots, league tables of pairwise comparisons, probability plots (rankograms), and inconsistency plots within Microsoft Excel. All figures generated are publication quality, thereby increasing the efficiency of knowledge transfer and manuscript preparation. Results We demonstrate the application of NetMetaXL using data from a network meta-analysis published previously which compares combined resynchronization and implantable defibrillator therapy in left ventricular dysfunction. We replicate results from the previous publication while demonstrating result summaries generated by the software. Conclusions Use of the freely available NetMetaXL successfully demonstrated its ability to make running network meta-analyses more accessible to novice WinBUGS users by allowing analyses to be conducted entirely within Microsoft Excel. NetMetaXL also allows

  10. The Geographic Climate Information System Project (GEOCLIMA): Overview and preliminary results

    Science.gov (United States)

    Feidas, H.; Zanis, P.; Melas, D.; Vaitis, M.; Anadranistakis, E.; Symeonidis, P.; Pantelopoulos, S.

    2012-04-01

    The project GEOCLIMA aims at developing an integrated Geographic Information System (GIS) allowing the user to manage, analyze and visualize the information which is directly or indirectly related to climate and its future projections in Greece. The main components of the project are: a) collection and homogenization of climate and environmental related information, b) estimation of future climate change based on existing regional climate model (RCM) simulations as well as a supplementary high resolution (10 km x 10 km) simulation over the period 1961-2100 using RegCM3, c) compilation of an integrated uniform geographic database, and d) mapping of climate data, creation of digital thematic maps, and development of the integrated web GIS application. This paper provides an overview of the ongoing research efforts and preliminary results of the project. First, the trends in the annual and seasonal time series of precipitation and air temperature observations for all available stations in Greece are assessed. Then the set-up of the high resolution RCM simulation (10 km x 10 km) is discussed with respect to the selected convective scheme. Finally, the relationship of climatic variables with geophysical features over Greece such as altitude, location, distance from the sea, slope, aspect, distance from climatic barriers, land cover etc) is investigated, to support climate mapping. The research has been co-financed by the European Union (European Regional Development Fund) and Greek national funds through the Operational Program "Competitiveness and Entrepreneurship" of the National Strategic Reference Framework (NSRF) - Research Funding Program COOPERATION 2009.

  11. Desempenho do modelo AcquaNetXL na alocação de água em sistemas de recursos hídricos complexos Performance of the model called AcquaNetXL in the allocation of water in complex water resource systems

    Directory of Open Access Journals (Sweden)

    André Schardong

    2009-01-01

    Full Text Available Este artigo apresenta uma ferramenta para análise de sistemas complexos de recursos hídricos denominada AcquaNetXL, que foi desenvolvida no formato de planilha eletrônica, na qual foram incorporados dois modelos de otimização, um linear e outro não linear. Essa ferramenta mantém os conceitos e os atributos de um sistema de suporte a decisão, ou seja, possui as características de estreitar a comunicação entre o usuário e o computador, de facilitar o entendimento, a formulação do problema, a interpretação dos resultados de análise e auxiliar no processo de tomada de decisão, tornando-o mais ordenado, objetivo e transparente. O desempenho do algoritmo utilizado na solução dos problemas de alocação de água foi satisfatório, especialmente para o modelo linear.This article presents a tool for the allocation analysis of complex systems of water resources, called AcquaNetXL, developed in the form of spreadsheet in which a model of linear optimization and another nonlinear were incorporated. The AcquaNetXL keeps the concepts and attributes of a decision support system. In other words, it straightens out the communication between the user and the computer, facilitates the understanding and the formulation of the problem, the interpretation of the results and it also gives a support in the process of decision making, turning it into a clear and organized process. The performance of the algorithms used for solving the problems of water allocation was satisfactory especially for the linear model.

  12. Inzicht in de netwerken op Facebook : Fanpages Analyse van Facebook Fanpages met behulp van de netwerkanalysetool NodeXL

    NARCIS (Netherlands)

    Sanne Gaastra; Sonja Utz

    2013-01-01

    Hoe analyseer je het netwerk van fans op je Facebookpagina? En wat zegt dat over de kracht van posts en actoren. In dit whitepaper zetten we uiteen hoe je het gratis programma NodeXL een visuele analyse van je pagina kunt maken. Interessant voor organisaties. Met deze kennis kun je immers gericht

  13. DHT inhibits the Aβ25-35-induced apoptosis by regulation of seladin-1, survivin, XIAP, bax, and bcl-xl expression through a rapid PI3-K/Akt signaling in C6 glial cell lines.

    Science.gov (United States)

    Bing, Lelin; Wu, Junfeng; Zhang, Jianfeng; Chen, Yinghui; Hong, Zhen; Zu, Hengbing

    2015-01-01

    Previous evidences indicate that androgen is neuroprotective in the brain. However, the underling mechanisms remain to be fully elucidated. Moreover, it is controversial whether dihydrotestosterone (DHT) modulates the expression of apoptosis-related effectors, such as survivin, XIAP, bax, and bcl-xl proteins mediated by the PI3-K/Akt pathway, which contributes to androgen neuroprotection. In this study using a C6 glial cell model, apoptotic cells were detected by flow cytometry. Akt, seladin-1, survivin, XIAP, bcl-xl, and bax protein expression is investigated by Western blot. After amyloid β-protein fragment (Aβ25-35) treatment, apoptotic cells at early (annexin V+, PI-) and late (annexin V+, PI+) stages were significantly increased. Apoptosis at early and late was obviously inhibited in the presence of DHT. The effect of DHT was markedly blocked by PI3-K inhibitor LY294002.To elicit the mechanism of DHT protection, the expression of seladin-1, survivin, XIAP, bax, and bcl-xl protein was determined in C6 cells treated with Aβ25-35, DHT, or LY294002. Aβ25-35 significantly downregulated the expression of seladin-1, survivin, XIAP, bcl-xl protein and upregulated the expression of bax protein. DHT significantly inhibited the expression of bax, seladin-1, survivin, XIAP, and bcl-xl protein induced by Aβ25-35. Further, we found the effect of DHT was significantly inhibited by LY294002. Collectively, in a C6 glial cell model, we firstly found that DHT inhibits Aβ25-35-induced apoptosis by a rapid nongenic PI-3K/Akt activation as well as regulation of seladin-1, survivin, XIAP, bcl-xl, and bax proteins.

  14. Unjuk Kerja Jaringan Seluler 2G dan 3G PT. XL Axiata di Area Jawa Tengah Bagian Utara setelah Proyek Swap dan Modernisasi

    Directory of Open Access Journals (Sweden)

    Eva Yovita Dwi Utami

    2015-04-01

    Full Text Available The increasing number of customers and the need for reliable communication require the availability of coverage, sufficient capacity and good quality of mobile communications networks. New BTS implementation is required to cover a wider area with good network quality. However, it often requires high cost and long time to get permission from the government and local residents. Swap and Modernization Project is a project that swap the previous 3G equipment using BTS 3900 Huawei with Ericsson RBS 6000 and modernize the 2G RBS 2000 to RBS 6000 and then carry out parameter settings to optimize the network. In this paper, we report the results of mobile network performance after Swap and Modernization projects had been done in terms of the signal strength improvements, which are showed by Rx Level, RSCP and CDD Dump parameters. The study was conducted in PT XL Axiata Northern Areas of Central Java with D5 cluster as a sample. The results show improvement of Rx Level that increased by 89.93 %, and RSCP value increased by 58.36 %. The swap and modernization of the BTS and parameter settings are able to improve CDD Dump parameters. These improvements are able to expand the coverage area of cluster D5 sites.

  15. Greenridge Multi-Pollutant Control Project Preliminary Public Design Report

    Energy Technology Data Exchange (ETDEWEB)

    Connell, Daniel P

    2009-01-12

    the commercial readiness of an emissions control system that is specifically designed to meet the environmental compliance requirements of these smaller coal-fired EGUs. The multi-pollutant control system is being installed and tested on the AES Greenidge Unit 4 (Boiler 6) by a team including CONSOL Energy Inc. as prime contractor, AES Greenidge LLC as host site owner, and Babcock Power Environmental Inc. as engineering, procurement, and construction contractor. All funding for the project is being provided by the U.S. Department of Energy, through its National Energy Technology Laboratory, and by AES Greenidge. AES Greenidge Unit 4 is a 107 MW{sub e} (net), 1950s vintage, tangentially-fired, reheat unit that is representative of many of the 440 smaller coal-fired units identified above. Following design and construction, the multi-pollutant control system will be demonstrated over an approximately 20-month period while the unit fires 2-4% sulfur eastern U.S. bituminous coal and co-fires up to 10% biomass. This Preliminary Public Design Report is the first in a series of two reports describing the design of the multi-pollutant control facility that is being demonstrated at AES Greenidge. Its purpose is to consolidate for public use all available nonproprietary design information on the Greenidge Multi-Pollutant Control Project. As such, the report includes a discussion of the process concept, design objectives, design considerations, and uncertainties associated with the multi-pollutant control system and also summarizes the design of major process components and balance of plant considerations for the AES Greenidge Unit 4 installation. The Final Public Design Report, the second report in the series, will update this Preliminary Public Design Report to reflect the final, as-built design of the facility and to incorporate data on capital costs and projected operating costs.

  16. Preliminary waste acceptance requirements - Konrad repository project

    International Nuclear Information System (INIS)

    Brennecke, P.W.; Warnecke, E.H.

    1991-01-01

    In Germany, the planned Konrad repository is proposed for the disposal of all types of radioactive wastes whose thermal influence upon the host rock is negligible. The Bundesamt fuer Strahlenschutz has established Preliminary Waste Acceptance Requirements (as of April 1990) for this facility. The respective requirements were developed on the basis of the results of site-specific safety assessments. They include general requirements on the waste packages to be disposed of as well as more specific requirements on the waste forms, the packaging and the radionuclide inventory per waste package. In addition, the delivery of waste packages was regulated. An outline of the structure and the elements of the Preliminary Waste Acceptance Requirements of April 1990 is given including comments on their legal status. (Author)

  17. Application of Boosting Regression Trees to Preliminary Cost Estimation in Building Construction Projects

    Directory of Open Access Journals (Sweden)

    Yoonseok Shin

    2015-01-01

    Full Text Available Among the recent data mining techniques available, the boosting approach has attracted a great deal of attention because of its effective learning algorithm and strong boundaries in terms of its generalization performance. However, the boosting approach has yet to be used in regression problems within the construction domain, including cost estimations, but has been actively utilized in other domains. Therefore, a boosting regression tree (BRT is applied to cost estimations at the early stage of a construction project to examine the applicability of the boosting approach to a regression problem within the construction domain. To evaluate the performance of the BRT model, its performance was compared with that of a neural network (NN model, which has been proven to have a high performance in cost estimation domains. The BRT model has shown results similar to those of NN model using 234 actual cost datasets of a building construction project. In addition, the BRT model can provide additional information such as the importance plot and structure model, which can support estimators in comprehending the decision making process. Consequently, the boosting approach has potential applicability in preliminary cost estimations in a building construction project.

  18. 77 FR 66580 - Notice of Availability of the Record of Decision (ROD) for the Gulf Coast Pipeline Project

    Science.gov (United States)

    2012-11-06

    ... subordinate its rights, acquired under the Wetland Reserve Program, to allow the Gulf Coast Segment (Gulf.... Department of State (DOS) to build and operate the Keystone XL Project. In the original application, Trans... built in three segments: The approximately 850-mile long ``Steele City'' segment from the U.S. border to...

  19. Characterization of radiochromic films EBT3 by means of the scanner Vidar dosimetry Pro Red and Epson 10000-XL use; Caracterizacion de films radiocromicos EBT3 mediante el uso de scanner Vidar dosimetry Pro Red y Epson 10000-XL

    Energy Technology Data Exchange (ETDEWEB)

    Medina, L.; Garrigo, E.; Venencia, D.; Adrada, A.; Filipuzzi, M., E-mail: fisicamedina11@gmail.com [Instituto Privado de Radioterapia, Obispo Oro 423, X5000BFI Cordoba (Argentina)

    2014-08-15

    The Radiochromic film have become an attractive tool for verification of dose distributions in IMRT because these have high spatial resolution film, are near water equivalent and not require revealed, A critical aspect of the use of these film is used for digitizing scanner The purpose of this paper is to characterize EBT3 using two types of scanner. Were employed The Radiochromic film EBT3, was used photon beam 6 MV generated by a linear accelerator Siemens Primus, he films were irradiated at a dose range between 0 Gy a 9 Gy. The stabilization time after irradiation was 24 hours. The films were digitized with a scanner Epson 10000-XL y el VIDAR Dosimetry Pro Red. We used the software for construction of the calibration curve. The resolution of each dosimetry system was analyzed through the results of the spatial response function by analyzing a step pattern. The Epson scanner is most sensitive to the red channel. This is less than that obtained with the Vidar. The Vidar scanner spatial response profiles disturbs not opposed to Epson analyzed. The calibration curves for both dosimetry systems can be employed. However, the sensitivity and repeatability of the system is better than Red Vidar Epson 10000-XL. (author)

  20. PRELIMINARY PROJECT PLAN FOR LANSCE INTEGRATED FLIGHT PATHS 11A, 11B, 12, and 13

    International Nuclear Information System (INIS)

    Bultman, D. H.; Weinacht, D.

    2000-01-01

    This Preliminary Project Plan Summarizes the Technical, Cost, and Schedule baselines for an integrated approach to developing several flight paths at the Manual Lujan Jr. Neutron Scattering Center at the Los Alamos Neutron Science Center. For example, the cost estimate is intended to serve only as a rough order of magnitude assessment of the cost that might be incurred as the flight paths are developed. Further refinement of the requirements and interfaces for each beamline will permit additional refinement and confidence in the accuracy of all three baselines (Technical, Cost, Schedule)

  1. Small-scale hydro power in the Anniviers Valley. Project Ayer-Nava. Variants and preliminary project; Forces Motrices de la Gougra SA. Mini-hydraulique en Anniviers. Projet Ayer-Nava. Etude de variantes et avant-projet

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2008-04-15

    This report for the Swiss Federal Office of Energy (SFOE) reports on the preliminary project for a small hydropower plant near Ayer, a village in the Anniviers Valley (Swiss Alps). Water from the Nava, a steep mountain river, should be lead into a hydraulic scheme for power generation. A hydraulic head of 400 to 550 m is available, depending on the variant considered. The corresponding expected mechanical power is 0.9 to 1.1 MW. For the most promising variant a preliminary project is described (peak electric power: 0.91 MW, annual electrical energy production: 3.1 GWh). The local geology and hydrogeology are presented. The water collection points, conduits and the power station are described. Technical details on water quantities and energy production are presented. Financial aspects including construction and operating costs are presented and the economic viability of the project is discussed. Environmental aspects are reviewed. Further steps to be taken in the realisation of this hydropower installation are listed.

  2. Validation and optimization of the Ion Torrent S5 XL sequencer and Oncomine workflow for BRCA1 and BRCA2 genetic testing.

    Science.gov (United States)

    Shin, Saeam; Kim, Yoonjung; Chul Oh, Seoung; Yu, Nae; Lee, Seung-Tae; Rak Choi, Jong; Lee, Kyung-A

    2017-05-23

    In this study, we validated the analytical performance of BRCA1/2 sequencing using Ion Torrent's new bench-top sequencer with amplicon panel with optimized bioinformatics pipelines. Using 43 samples that were previously validated by Illumina's MiSeq platform and/or by Sanger sequencing/multiplex ligation-dependent probe amplification, we amplified the target with the Oncomine™ BRCA Research Assay and sequenced on Ion Torrent S5 XL (Thermo Fisher Scientific, Waltham, MA, USA). We compared two bioinformatics pipelines for optimal processing of S5 XL sequence data: the Torrent Suite with a plug-in Torrent Variant Caller (Thermo Fisher Scientific), and commercial NextGENe software (Softgenetics, State College, PA, USA). All expected 681 single nucleotide variants, 15 small indels, and three copy number variants were correctly called, except one common variant adjacent to a rare variant on the primer-binding site. The sensitivity, specificity, false positive rate, and accuracy for detection of single nucleotide variant and small indels of S5 XL sequencing were 99.85%, 100%, 0%, and 99.99% for the Torrent Variant Caller and 99.85%, 99.99%, 0.14%, and 99.99% for NextGENe, respectively. The reproducibility of variant calling was 100%, and the precision of variant frequency also showed good performance with coefficients of variation between 0.32 and 5.29%. We obtained highly accurate data through uniform and sufficient coverage depth over all target regions and through optimization of the bioinformatics pipeline. We confirmed that our platform is accurate and practical for diagnostic BRCA1/2 testing in a clinical laboratory.

  3. Fort Hood Solar Total Energy Project. Volume II. Preliminary design. Part 1. System criteria and design description. Final report

    Energy Technology Data Exchange (ETDEWEB)

    None,

    1979-01-01

    This volume documents the preliminary design developed for the Solar Total Energy System to be installed at Fort Hood, Texas. Current system, subsystem, and component designs are described and additional studies which support selection among significant design alternatives are presented. Overall system requirements which form the system design basis are presented. These include program objectives; performance and output load requirements; industrial, statutory, and regulatory standards; and site interface requirements. Material in this section will continue to be issued separately in the Systems Requirements Document and maintained current through revision throughout future phases of the project. Overall system design and detailed subsystem design descriptions are provided. Consideration of operation and maintenance is reflected in discussion of each subsystem design as well as in an integrated overall discussion. Included are the solar collector subsystem; the thermal storage subsystem, the power conversion sybsystem (including electrical generation and distribution); the heating/cooling and domestic hot water subsystems; overall instrumentation and control; and the STES building and physical plant. The design of several subsystems has progressed beyond the preliminary stage; descriptions for such subsystems are therefore provided in more detail than others to provide complete documentation of the work performed. In some cases, preliminary design parameters require specific verificaton in the definitive design phase and are identified in the text. Subsystem descriptions will continue to be issued and revised separately to maintain accuracy during future phases of the project. (WHK)

  4. Denmark's greenhouse gas projections until 2012, an update including a preliminary projection until 2017

    International Nuclear Information System (INIS)

    Fenham, J.

    2003-01-01

    This report presents the results of a project financed by the Danish Energy Agency. The purpose of the project is to make 'with measures' projections of the emissions from Danish sources of the greenhouse gases, CO 2 , CH 4 , N 2 O, HFCs, PFCs and SF 6 . The 'with measures' projection encompasses currently implemented and adopted policies and measures. The time period covered is from 1972, the first year detailed Danish energy statistics were produced, until the first commitment period (2008-2012) under the Kyoto Protocol to the Climate Convention. A preliminary projection is also made for the second commitment period (2013-2017), but here no projections are available for the agricultural sector and the emissions from this sector has therefore been kept equal to the emissions in the first commitment period. Estimations of HFCs, PFCs and SF 6 -emissions and projections cover the period from 1993 until 2020. Only emissions caused by human activities are included in the calculations. However, it can sometimes be difficult to draw the borderline between emissions from nature and anthropogenic emissions. Due to small differences between the methodology used in this project and the methodology (CORINAIR) used by the National Environmental Research Institute for the purpose of annual reporting the estimated emissions presented for the period 1990-2000 may deviate from the official emission estimates report to the EU and the Climate Convention (UNFCCC). Therefore the GHG emission estimates presented in this report for the period until 2000 should only be seen as an illustration of the order of magnitude. This is also the case for the parts of the trend analyses, which are based on the historic data coming from this project. The description of the emissions in the report is structured according to the IPCC sectors: 1) Energy. 2) Industrial processes. 3) Agriculture. 4) Land use change and forestry. 5) Waste. The NMVOC emission from solvent use and other sources is included

  5. The MACHO Project: Preliminary Results from 4 years of SMC observations.

    Science.gov (United States)

    Vandehei, T.; Griest, K.; Lehner, M.; Alcock, C.; Alves, D.; Cook, K.; Marshall, S.; Minniti, D.; Allsman, R.; Axelrod, T.; Freeman, K.; Peterson, B.; Rodgers, A.; Pratt, M.; Becker, A.; Stubbs, C.; Tomaney, A.; Bennett, D.; Quinn, P.; Sutherland, W.; Welch, D.

    1997-12-01

    The MACHO project is a search for dark matter in the form of massive compact halo objects(MACHOs). The project has photometrically monitored tens of millions of stars in the Large Magellanic Cloud (LMC), Small Magellanic Cloud (SMC), and Galactic bulge in search of rare gravitational microlensing events caused by these otherwise invisible objects. Microlensing toward the LMC has allowed powerful statements to be made about the dark population in the halo of our Galaxy, indicating that the MACHO halo fraction could be as high as f=0.5 with a most probable MACHO mass being ~ 0.5Msun. However, to date the LMC has been the only line of sight out of our Galaxy's halo. Clearly, another line of sight would provide a consistency check on these results, as well as another contraint on models of the halo, in particular on halo flattening. The SMC affords us this second line of sight. Here we give a status report on our upcoming 4 year results toward the SMC. We present the results of a preliminary analysis on over 2.2 million stars from 3 square degrees and discuss the implications for the dark matter in the halo of our Galaxy. A detailed analysis of the microlensing candidates toward the SMC, with blending and parallax fits, will be shown. This work is dedicated to the memory of Alex Rodgers.

  6. Stress analysis of HLW containers. Preliminary ring test exercise Compas project

    International Nuclear Information System (INIS)

    1989-01-01

    This document describes the series of experiments and associated calculations performed as the Compas preliminary ring test exercise. A number of mild steel rings, representative of sections through HLW containers, some notched and pre-cracked, were tested in compression right up to and beyond their ultimate load. The Compas project partners independently modelled the behaviour of these rings using their finite element codes. Four different ring types were tested, and each test was repeated three times. For three of the ring types, the three test repetitions gave identical results. The fourth ring, which was not modelled by the partners, had a 4 mm thick layer of weld metal deposited on its surface. The three tests on this ring did not give identical results and suggested that the effect of welding methods should be addressed at a later stage of the project. Fracture was not found to be a significant cause of ring failure. The results of the ring tests were compared with the partners predictions, and additionally some time was spent assessing where the use of the codes could be improved. This exercise showed that the partners codes have the ability to produce results within acceptable limits. Most codes were unable to model stable crack growth. There were indications that some codes would not be able to cope with a significantly more complex three-dimensional analysis

  7. Pengaruh Tukul Arwana Sebagai Celebrity Endorser Terhadap Brand Awareness Masyarakat (Studi Kasus Iklan Xl Versi Tukul Arwana)

    OpenAIRE

    khoiruman, muhammad

    2015-01-01

    Considerations to be made by marketers in selecting endoser a product other products form the basis of this study. This study aims to determine the effect attributes (performance) endorser of the brand awareness Tukul Arwana in advertising XL. This research is a survey with a sample of the overall amount to 120 respondents. The sampling technique used was purposive sampling. Data collection instruments such as questionnaires and analysis tools used multiple linear regression. Based on the res...

  8. F-16XL Ship #2 in hangar for Laminar Flow Glove mounting

    Science.gov (United States)

    1995-01-01

    NASA's two-seat F-16XL research aircraft is shown in the modification hangar at the Dryden Flight Research Center, Edwards, California, during installation of a titanium 'glove' on the upper surface of its modified left wing. The aircraft subsequently concluded a 13 month-long, 45-flight research program which investigated drawing off a small portion of the boundary-layer air in order to provide laminar -- or smooth -- flow over a major portion of a wing flying at supersonic speeds. A turbo-compressor in the aircraft's fuselage provided suction to draw air through more than 10 million tiny laser-drilled holes in the glove via a manifold system employing 20 valves. Data obtained during the program could assist designers of future high-speed aircraft in developing a more efficient civil transport.

  9. Scope and purpose of the preliminary planning work

    International Nuclear Information System (INIS)

    Kalas, P.

    1976-01-01

    The results of preliminary planning work are usually expressed in a number of recommendations covering mainly: long-term national policy in the field of energy resources and selection of projects to be further studied at the feasibility level. Moreover, recommendations on further actions are made including: inventory of generation and transmission facilities recommended for the implementation in order to meet the load forecasted for medium-term period, preparation of a preliminary calender of decisions to be taken for the implementation of the projects recommended, preparation of a preliminary construction schedule, preparation of a preliminary investment program, preparation of a program of necessary engineering works, and performance of study on electricity rates which would adjust existing tariffs to proposed development program of the utility. (HP) [de

  10. 32 CFR 644.30 - Preliminary real estate work.

    Science.gov (United States)

    2010-07-01

    ... 32 National Defense 4 2010-07-01 2010-07-01 true Preliminary real estate work. 644.30 Section 644... PROPERTY REAL ESTATE HANDBOOK Project Planning Military (army and Air Force) and Other Federal Agencies § 644.30 Preliminary real estate work. (a) Preliminary real estate work is defined as that action taken...

  11. Trevino Project: a fast-track approach for a small construction project

    International Nuclear Information System (INIS)

    Schick, C.J.; Lynn, N.S.

    1982-01-01

    The approach to a construction project can vary according to the size, location, and degree of difficulty associated with the project. This paper deals with one approach that can be taken to a small construction project, the fast-track approach. A small construction project can be defined as a project having less than $20 million capital cost or a project with a low degree of difficulty. This approach is very applicable to in-situ leaching uranium projects, small precious metal operations, etc. The approach to the small project is that of fast-tracking the project in order to minimize the time over which capital expenditure occurs and also to reduce the indirect costs of field expense, construction supplies, construction equipment, etc. In order to fast-track a project it is necessary to do a very precise job on the preliminary phases of the project such as preliminary engineering, plant site location, environmental permits, etc. 2 figures, 2 tables

  12. The influence of central corneal thickness and age on intraocular pressure measured by pneumotonometry, non-contact tonometry, the Tono-Pen XL, and Goldmann applanation tonometry

    OpenAIRE

    Tonnu, P-A; Ho, T; Newson, T; El Sheikh, A; Sharma, K; White, E; Bunce, C; Garway-Heath, D

    2005-01-01

    Aims: To evaluate the influence of central corneal thickness (CCT) on intraocular pressure (IOP) measurements made with the Goldmann applanation tonometer (GAT), Tono-Pen XL, ocular blood flow tonograph (OBF), and Canon TX-10 non-contact tonometer (NCT).

  13. Determination of the performance characteristics of a method for the measurement of total phosphorus in groundwater with the PE Optima 3000 XL ICP-AES

    NARCIS (Netherlands)

    Kohlmeyer U; Breugem PM; Boer JLM de; LAC

    1996-01-01

    Dit rapport behandelt de prestatiekenmerken van een methode voor de bepaling van totaal-fosfor in grondwater met behulp van ICP-AES met een axiaal plasma (Perkin-Elmer Optima 3000 XL). Met de reeds bestaande methode 'TotP' werden de volgende prestatiekenmerken vastgesteld:

  14. Preliminary identification of problem soils for infrastructure projects

    CSIR Research Space (South Africa)

    Paige-Green, P

    2008-11-01

    Full Text Available soils are those within the top 1.0m or 1.5m of the soil profile, a mechanism for evaluating these materials without preliminary filed work and testing would be invaluable. Since 1971, the Department of Agriculture has systematically mapped the soils...

  15. The BH3 α-Helical Mimic BH3-M6 Disrupts Bcl-XL, Bcl-2, and MCL-1 Protein-Protein Interactions with Bax, Bak, Bad, or Bim and Induces Apoptosis in a Bax- and Bim-dependent Manner*

    Science.gov (United States)

    Kazi, Aslamuzzaman; Sun, Jiazhi; Doi, Kenichiro; Sung, Shen-Shu; Takahashi, Yoshinori; Yin, Hang; Rodriguez, Johanna M.; Becerril, Jorge; Berndt, Norbert; Hamilton, Andrew D.; Wang, Hong-Gang; Sebti, Saïd M.

    2011-01-01

    A critical hallmark of cancer cell survival is evasion of apoptosis. This is commonly due to overexpression of anti-apoptotic proteins such as Bcl-2, Bcl-XL, and Mcl-1, which bind to the BH3 α-helical domain of pro-apoptotic proteins such as Bax, Bak, Bad, and Bim, and inhibit their function. We designed a BH3 α-helical mimetic BH3-M6 that binds to Bcl-XL and Mcl-1 and prevents their binding to fluorescently labeled Bak- or Bim-BH3 peptides in vitro. Using several approaches, we demonstrate that BH3-M6 is a pan-Bcl-2 antagonist that inhibits the binding of Bcl-XL, Bcl-2, and Mcl-1 to multi-domain Bax or Bak, or BH3-only Bim or Bad in cell-free systems and in intact human cancer cells, freeing up pro-apoptotic proteins to induce apoptosis. BH3-M6 disruption of these protein-protein interactions is associated with cytochrome c release from mitochondria, caspase-3 activation and PARP cleavage. Using caspase inhibitors and Bax and Bak siRNAs, we demonstrate that BH3-M6-induced apoptosis is caspase- and Bax-, but not Bak-dependent. Furthermore, BH3-M6 disrupts Bcl-XL/Bim, Bcl-2/Bim, and Mcl-1/Bim protein-protein interactions and frees up Bim to induce apoptosis in human cancer cells that depend for tumor survival on the neutralization of Bim with Bcl-XL, Bcl-2, or Mcl-1. Finally, BH3-M6 sensitizes cells to apoptosis induced by the proteasome inhibitor CEP-1612. PMID:21148306

  16. Optimisation of small-scale hydropower using quality assurance methods - Preliminary project; Vorprojekt: Optimierung von Kleinwasserkraftwerken durch Qualitaetssicherung. Programm Kleinwasserkraftwerke

    Energy Technology Data Exchange (ETDEWEB)

    Hofer, S.; Staubli, T.

    2006-11-15

    This comprehensive final report for the Swiss Federal Office of Energy (SFOE) presents the results of a preliminary project that examined how quality assurance methods can be used in the optimisation of small-scale hydropower projects. The aim of the project, to use existing know-how, experience and synergies, is examined. Discrepancies in quality and their effects on production prices were determined in interviews. The paper describes best-practice guidelines for the quality assurance of small-scale hydro schemes. A flow chart describes the various steps that have to be taken in the project and realisation work. Information collected from planners and from interviews made with them are presented along with further information obtained from literature. The results of interviews concerning planning work, putting to tender and the construction stages of these hydro schemes are presented and commented on. Similarly, the operational phase of such power plant is also examined, including questions on operation and guarantees. The aims of the follow-up main project - the definition of a tool and guidelines for ensuring quality - are briefly reviewed.

  17. A preliminary examination of audience-related communications issues for the Hanford Environmental Dose Reconstruction Project

    Energy Technology Data Exchange (ETDEWEB)

    Holmes, C.W.

    1991-04-01

    The Hanford Environmental Dose Reconstruction (HEDR) Project will estimate radiation doses people may have received from exposure to radioactive materials released during past operations at the US Department of Energy's (DOE) Hanford Site near Richland, Washington. The HEDR Project was initiated in response to public concerns about possible health impacts from past releases of radioactive materials from Hanford. The TSP recognized early in the project that special mechanisms would be required to effectively communicate to the many different concerned audiences. Accordingly, the TSP directed PNL to examine methods for communicating causes and effects of uncertainties in the dose estimates. After considering the directive and discussing it with the Communications Subcommittee of the TSP, PNL undertook a broad investigation of communications methods to consider for inclusion in the TSP's current communications program. As part of this investigation, a literature review was conducted regarding risk communications. A key finding was that, in order to successfully communicate risk-related information, a thorough understanding of the knowledge level, concerns and information needs of the intended recipients (i.e., the audience) is necessary. Hence, a preliminary audience analysis was conducted as part of the present research. This report summarizes the results of this analysis. 1 ref., 9 tabs.

  18. Characterization of radiochromic films EBT3 by means of the scanner Vidar dosimetry Pro Red and Epson 10000-XL use

    International Nuclear Information System (INIS)

    Medina, L.; Garrigo, E.; Venencia, D.; Adrada, A.; Filipuzzi, M.

    2014-08-01

    The Radiochromic film have become an attractive tool for verification of dose distributions in IMRT because these have high spatial resolution film, are near water equivalent and not require revealed, A critical aspect of the use of these film is used for digitizing scanner The purpose of this paper is to characterize EBT3 using two types of scanner. Were employed The Radiochromic film EBT3, was used photon beam 6 MV generated by a linear accelerator Siemens Primus, he films were irradiated at a dose range between 0 Gy a 9 Gy. The stabilization time after irradiation was 24 hours. The films were digitized with a scanner Epson 10000-XL y el VIDAR Dosimetry Pro Red. We used the software for construction of the calibration curve. The resolution of each dosimetry system was analyzed through the results of the spatial response function by analyzing a step pattern. The Epson scanner is most sensitive to the red channel. This is less than that obtained with the Vidar. The Vidar scanner spatial response profiles disturbs not opposed to Epson analyzed. The calibration curves for both dosimetry systems can be employed. However, the sensitivity and repeatability of the system is better than Red Vidar Epson 10000-XL. (author)

  19. Activity of selenium on cell proliferation, cytotoxicity, and apoptosis and on the expression of CASP9, BCL-XL and APC in intestinal adenocarcinoma cells

    Energy Technology Data Exchange (ETDEWEB)

    Mauro, M.O., E-mail: mari.mauro@hotmail.com [Graduate Program in Biological Sciences (Cell and Molecular Biology), Institute of Biosciences, UNESP, Rio Claro (SP) (Brazil); Sartori, Daniele [General Biology Department, State University of Londrina (UEL), Londrina (Brazil); Oliveira, Rodrigo Juliano [Coordination of Open and Distance Education, Graduate Program in Animal Science, Federal University of Mato Grosso do Sul (UFMS), Campo Grande (MS) (Brazil); Ishii, Priscila Lumi [Graduate Program in Biological Sciences (Cell and Molecular Biology), Institute of Biosciences, UNESP, Rio Claro (SP) (Brazil); Mantovani, Mario Sergio [General Biology Department, State University of Londrina (UEL), Londrina (Brazil); Ribeiro, Lucia Regina [Graduate Program in Biological Sciences (Cell and Molecular Biology), Institute of Biosciences, UNESP, Rio Claro (SP) (Brazil)

    2011-10-01

    Intestinal cancers are correlated with diet. Thus, determining and understanding nutrient-genome interactions is important. The present work assessed the action of the oligoelement selenium on cell proliferation, cytotoxicity, and in situ apoptosis induction and on the expression CASP9, BCL-XL and APC genes in intestinal adenocarcinoma cells (HT29). HT29 cells were cultured and treated with selenium at concentrations of 5, 50 and 500 ng/mL with or without the damage-inducing agent doxorubicin. These cells were then evaluated for cytotoxicity (MTT), cell proliferation and in situ apoptosis induction. To evaluate gene expression, only the cells treated with 500 ng/mL of selenium were used. RNA was extracted from these cells, and the expressions of CASP9, BCL-XL and APC were analyzed by the RT-PCR method. The GAPDH gene was used as a reference gene. The MTT assay showed that selenium was not cytotoxic at any of the concentrations tested. The cell proliferation assay showed that selenium did not interfere with cell proliferation at the three concentrations tested. In contrast, when the three concentrations were combined with doxorubicin, a significant decrease in the proliferation rate was observed. The apoptosis rate was significantly increased in the selenium (500 ng/mL) and doxorubicin group. CASP9 expression was increased and BCL-XL expression decreased in the selenium (500 ng/mL) and doxorubicin group. APC was significantly increased in the selenium group alone. These results show that selenium increases apoptosis, especially when it is associated with a damage-inducing agent. Also, selenium has an important role in the expression of the APC gene, which is related to cell cycle regulation.

  20. Activity of selenium on cell proliferation, cytotoxicity, and apoptosis and on the expression of CASP9, BCL-XL and APC in intestinal adenocarcinoma cells

    International Nuclear Information System (INIS)

    Mauro, M.O.; Sartori, Daniele; Oliveira, Rodrigo Juliano; Ishii, Priscila Lumi; Mantovani, Mario Sergio; Ribeiro, Lucia Regina

    2011-01-01

    Intestinal cancers are correlated with diet. Thus, determining and understanding nutrient-genome interactions is important. The present work assessed the action of the oligoelement selenium on cell proliferation, cytotoxicity, and in situ apoptosis induction and on the expression CASP9, BCL-XL and APC genes in intestinal adenocarcinoma cells (HT29). HT29 cells were cultured and treated with selenium at concentrations of 5, 50 and 500 ng/mL with or without the damage-inducing agent doxorubicin. These cells were then evaluated for cytotoxicity (MTT), cell proliferation and in situ apoptosis induction. To evaluate gene expression, only the cells treated with 500 ng/mL of selenium were used. RNA was extracted from these cells, and the expressions of CASP9, BCL-XL and APC were analyzed by the RT-PCR method. The GAPDH gene was used as a reference gene. The MTT assay showed that selenium was not cytotoxic at any of the concentrations tested. The cell proliferation assay showed that selenium did not interfere with cell proliferation at the three concentrations tested. In contrast, when the three concentrations were combined with doxorubicin, a significant decrease in the proliferation rate was observed. The apoptosis rate was significantly increased in the selenium (500 ng/mL) and doxorubicin group. CASP9 expression was increased and BCL-XL expression decreased in the selenium (500 ng/mL) and doxorubicin group. APC was significantly increased in the selenium group alone. These results show that selenium increases apoptosis, especially when it is associated with a damage-inducing agent. Also, selenium has an important role in the expression of the APC gene, which is related to cell cycle regulation.

  1. Denmark's greenhouse gas projections until 2012, an update including a preliminary projection until 2017

    Energy Technology Data Exchange (ETDEWEB)

    Fenham, J. [Risoe National Lab., Roskilde (Denmark)

    2003-07-01

    This report presents the results of a project financed by the Danish Energy Agency. The purpose of the project is to make 'with measures' projections of the emissions from Danish sources of the greenhouse gases, CO{sub 2}, CH{sub 4}, N{sub 2}O, HFCs, PFCs and SF{sub 6}. The 'with measures' projection encompasses currently implemented and adopted policies and measures. The time period covered is from 1972, the first year detailed Danish energy statistics were produced, until the first commitment period (2008-2012) under the Kyoto Protocol to the Climate Convention. A preliminary projection is also made for the second commitment period (2013-2017), but here no projections are available for the agricultural sector and the emissions from this sector has therefore been kept equal to the emissions in the first commitment period. Estimations of HFCs, PFCs and SF{sub 6}-emissions and projections cover the period from 1993 until 2020. Only emissions caused by human activities are included in the calculations. However, it can sometimes be difficult to draw the borderline between emissions from nature and anthropogenic emissions. Due to small differences between the methodology used in this project and the methodology (CORINAIR) used by the National Environmental Research Institute for the purpose of annual reporting the estimated emissions presented for the period 1990-2000 may deviate from the official emission estimates report to the EU and the Climate Convention (UNFCCC). Therefore the GHG emission estimates presented in this report for the period until 2000 should only be seen as an illustration of the order of magnitude. This is also the case for the parts of the trend analyses, which are based on the historic data coming from this project. The description of the emissions in the report is structured according to the IPCC sectors: 1) Energy. 2) Industrial processes. 3) Agriculture. 4) Land use change and forestry. 5) Waste. The NMVOC emission from

  2. 77 FR 74845 - AJT Mining Properties, Inc.; Notice of Surrender of Preliminary Permit

    Science.gov (United States)

    2012-12-18

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Project No. 14115-001] AJT Mining Properties, Inc.; Notice of Surrender of Preliminary Permit Take notice that AJT Mining Properties, Inc., permittee for the proposed Yeldagalga Creek Hydroelectric Project, has requested that its preliminary permit...

  3. Comparison of three methods of tonometry in normal subjects: Goldmann applanation tonometer, non-contact airpuff tonometer, and Tono-Pen XL

    OpenAIRE

    Yilmaz, Ihsan; Altan,Cigdem; Aygit,Ebru Demet; Alagoz,Cengiz; Baz,Okkes; Ahmet,Sibel; Urvasizoglu,Semih; Yaşa,Dilek; Demirok,Ahmet

    2014-01-01

    Ihsan Yilmaz, Cigdem Altan, Ebru Demet Aygit, Cengiz Alagoz, Okkes Baz, Sibel Ahmet, Semih Urvasizoglu, Dilek Yasa, Ahmet DemirokBeyoglu Eye Training and Research Hospital, Istanbul, TurkeyObjective: We aimed to compare intraocular pressure (IOP) measurements via three different tonometers: the Goldmann applanation tonometer (GAT), the Tono-Pen® XL (TPXL), and a non-contact airpuff tonometer (NCT).Methods: This was a cross-sectional study of 200 eyes from 20...

  4. Preliminary report on the Northern California Power Agency's Notice of Intention to seek certification for NCPA Geothermal Project No. 2

    Energy Technology Data Exchange (ETDEWEB)

    1978-01-01

    This preliminary report on the Northern California Power Agency (NCPA) geothermal power plant proposal has been prepared pursuant to California Public Resources Code Sections 25510, 25512, and 25540. It presents the preliminary Findings of fact and Conclusions adopted by the Commission Committee assigned to conduct proceedings on the Notice. In addition, the report contains a description of the proposed project, a summary of the proceedings to date, and local, state, and Federal government agency comments on the proposal. Finally, the report presents the Committee's view of those issues that require further consideration in future proceedings on the Notice. Pursuant to Public Resources Code Sections 25512 and 25540, the report presents preliminary Findings and Conclusions on: (1) conformity to the forecast of statewide and service area electric power demands; (2) the degree to which the proposed site and facility conform with applicable local, regional, state and Federal standards, ordinances, and laws; and (3) the safety and reliability of the facility.

  5. The Agricultural Model Intercomparison and Improvement Project (AgMIP): Progress and Preliminary Results

    Science.gov (United States)

    Rosenzweig, C.

    2011-12-01

    The Agricultural Model Intercomparison and Improvement Project (AgMIP) is a distributed climate-scenario simulation exercise for historical model intercomparison and future climate change conditions with participation of multiple crop and agricultural trade modeling groups around the world. The goals of AgMIP are to improve substantially the characterization of risk of hunger and world food security due to climate change and to enhance adaptation capacity in both developing and developed countries. Recent progress and the current status of AgMIP will be presented, highlighting three areas of activity: preliminary results from crop pilot studies, outcomes from regional workshops, and emerging scientific challenges. AgMIP crop modeling efforts are being led by pilot studies, which have been established for wheat, maize, rice, and sugarcane. These crop-specific initiatives have proven instrumental in testing and contributing to AgMIP protocols, as well as creating preliminary results for aggregation and input to agricultural trade models. Regional workshops are being held to encourage collaborations and set research activities in motion for key agricultural areas. The first of these workshops was hosted by Embrapa and UNICAMP and held in Campinas, Brazil. Outcomes from this meeting have informed crop modeling research activities within South America, AgMIP protocols, and future regional workshops. Several scientific challenges have emerged and are currently being addressed by AgMIP researchers. Areas of particular interest include geospatial weather generation, ensemble methods for climate scenarios and crop models, spatial aggregation of field-scale yields to regional and global production, and characterization of future changes in climate variability.

  6. The CUORE/CUORICINO project: preliminary studies

    International Nuclear Information System (INIS)

    Brofferio, C.

    2000-01-01

    A 1-t bolometer detector, aiming at the search for neutrinoless double-beta decay, cold dark matter, and solar axions with extremely high sensitivity, has been proposed (CUORE project). At the moment, the construction of a 420 kg array of 56 TeO 2 bolometers (CUORICINO project) has been approved and is financed. CUORICINO will be a feasibility test for CUORE, while increasing the present sensitivity on 0νββ half-life of 130 Te (1 x 10 23 yr, 90% C.L.) The scale of the art of CUORICINO, together with the physical motivations and the technical feasibility of the CUORE project are briefly discussed [ru

  7. The CUORE/CUORICINO project: Preliminary studies

    International Nuclear Information System (INIS)

    Brofferio, C.

    2000-01-01

    A 1-t bolometer detector, aiming at the search for neutrinoless double-beta decay, cold dark matter, and solar axions with extremely high sensitivity, has been proposed (CUORE project). At the moment, the construction of a 42-kg array of 56 TeO 2 bolometers (CUORICINO project) has been approved and is financed. CUORICINO will be a feasibility test for CUORE, while increasing the present sensitivity on 0νββ half-life of 130 Te (1 x 10 23 yr, 90% C.L.). The state of the art of CUORICINO, together with the physical motivations and the technical feasibility of the CUORE project, is briefly discussed

  8. AXAOTHER XL -- A spreadsheet for determining doses for incidents caused by tornadoes or high-velocity straight winds

    International Nuclear Information System (INIS)

    Simpkins, A.A.

    1996-09-01

    AXAOTHER XL is an Excel Spreadsheet used to determine dose to the maximally exposed offsite individual during high-velocity straight winds or tornado conditions. Both individual and population doses may be considered. Potential exposure pathways are inhalation and plume shine. For high-velocity straight winds the spreadsheet has the capability to determine the downwind relative air concentration, however for the tornado conditions, the user must enter the relative air concentration. Theoretical models are discussed and hand calculations are performed to ensure proper application of methodologies. A section has also been included that contains user instructions for the spreadsheet

  9. Preliminary project of s Thomson scattering system for the ETE tokamak; Projeto preliminar de um sistema de espalhamento Thomson para o Tokamak ETE

    Energy Technology Data Exchange (ETDEWEB)

    Berni, Luiz Angelo

    1997-12-31

    This report presents the preliminary project of the injection and laser light block system for the Thomson (ET) scattering diagnostic to be implanted at the ETE spheric tokamak of the Instituto Nacional de Pesquisas Espaciais (INPE/LAP). Also, a scanning system for the optics of scattered light 4 refs., 26 figs.

  10. Preliminary results of the PREFER FP7 Project

    Science.gov (United States)

    Fusilli, Lorenzo; Laneve, Giovanni; De Bonis, Roberto; Sebastian, Ana; Ferrucci, Fabrizio; Oliveira, Sandra

    2014-05-01

    The need to improve the information and intelligence support for forest fire prevention is widely recognized. Fire prevention is still the most cost-effective strategy when compared to firefighting and extinguishing that are costly, local, and triggered only in response to already ongoing crises. PREFER project, funded under the EU FP7 (G.A. 312931), intends to contribute at responding to such a pragmatic need of southern Europe's forests by: providing timely information products based on the exploitation of all available spacecraft sensors, offering a portfolio of products focused on pre- and post-crisis forest fire emergency, suitable for the users in the different countries of the European Mediterranean area. The PREFER Service portfolio consists of two main services: 1. Information Support to Fire Preparedness/Prevention Phase" (ISP) Service 2. Information Support to Fire Recovery/Reconstruction Phase" (ISR) Service This service is already at an advanced stage having completed the first year of activity. During this time several products have been consolidated: seasonal fuel maps; daily and seasonal fire hazard maps; seasonal risk maps; prescribed fire maps. This paper aims at presenting the preliminary results of the research activity carried out in the framework of the PREFER project, focusing, in particular, on these recalled above. As for Fire Risk and Hazard assessment, many indexes have been developed in the last years. Hardly any of them uses data derived from satellite images. The FPI index is an exception to this rule which, in addition, makes use of meteorological data. In spite of being a very complete index, the FPI still allows room for improvement which justify the interest of PREFER in it. PREFER's innovative approach to FPI will allow taking into account the effect of solar illumination conditions in determining the humidity present in the dead vegetation, and therefore its proneness to burn. PREFER innovation also focus in allowing the index to

  11. Agreement among Goldmann applanation tonometer, iCare, and Icare PRO rebound tonometers; non-contact tonometer; and Tonopen XL in healthy elderly subjects.

    Science.gov (United States)

    Kato, Yoshitake; Nakakura, Shunsuke; Matsuo, Naoko; Yoshitomi, Kayo; Handa, Marina; Tabuchi, Hitoshi; Kiuchi, Yoshiaki

    2018-04-01

    To evaluate the inter-device agreement among the Goldmann applanation tonometer (GAT), iCare and Icare PRO rebound tonometers, non-contact tonometer (NCT), and Tonopen XL tonometer. Sixty healthy elderly subjects were enrolled. The intraocular pressure (IOP) in each subject's right eye was measured thrice using each of the five tonometers. Intra-device agreement was evaluated by calculating intraclass correlation coefficients (ICCs). Inter-device agreement was evaluated by ICC and Bland-Altman analyses. ICCs for intra-device agreement for each tonometer were >0.8. IOP as measured by iCare (mean ± SD, 11.6 ± 2.5 mmHg) was significantly lower (p tonometers (all ICCs tonometers ranged from 14.94 to 16.47 mmHg. Among the other tonometers, however, the widths of 95% limits of agreement ranged from 7.91 to 9.24 mmHg. There was good inter-device agreement among GAT, rebound tonometers, and NCT. Tonopen XL shows the worst agreement with the other tonometers; therefore, we should pay attention to its' respective IOP. Japan Clinical Trials Register; number: UMIN000011544.

  12. Pre-contract project scoping processes : synthesis of practices.

    Science.gov (United States)

    2016-02-01

    Scoping is the process of developing a projects objectives, need, preliminary cost estimate, and preliminary schedule based on a : recognized need that the project is intended to address. This study (INDOT/JTRP SPR-3944) was launched by the Indian...

  13. Transient elastography with the XL probe rapidly identifies patients with nonhepatic ascites

    Directory of Open Access Journals (Sweden)

    Mueller S

    2012-05-01

    Full Text Available Anna Kohlhaas1, Esteban Durango1, Gunda Millonig1, Cecile Bastard2, Laurent Sandrin2, Mohammad Golriz3, Arianeb Mehrabi3, Markus W Büchler3, Helmut Karl Seitz1, Sebastian Mueller11Department of Medicine and Center for Alcohol Research, Liver Disease and Nutrition, Salem Medical Center, University of Heidelberg, Heidelberg, Germany; 2Department of Research and Development, Echosens, Paris, France; 3Department of General, Visceral and Transplantation Surgery, University of Heidelberg, Heidelberg, GermanyBackground: In contrast with other elastographic techniques, ascites is considered an exclusion criterion for assessment of fibrosis stage by transient elastography. However, a normal liver stiffness could rule out hepatic causes of ascites at an early stage. The aim of the present study was to determine whether liver stiffness can be generally determined by transient elastography through an ascites layer, to determine whether the ascites-mediated increase in intra-abdominal pressure affects liver stiffness, and to provide initial data from a pilot cohort of patients with various causes of ascites.Methods and results: Using the XL probe in an artificial ascites model, we demonstrated (copolymer phantoms surrounded by water that a transient elastography-generated shear wave allows accurate determination of phantom stiffness up to a water lamella of 20 mm. We next showed in an animal ascites model that increased intra-abdominal pressure does not affect liver stiffness. Liver stiffness was then determined in 24 consecutive patients with ascites due to hepatic (n = 18 or nonhepatic (n = 6 causes. The cause of ascites was eventually clarified using routine clinical, imaging, laboratory, and other tools. Valid (75% or acceptable (25% liver stiffness data could be obtained in 23 patients (95.8% with ascites up to an ascites lamella of 39 mm. The six patients (25% with nonhepatic causes of ascites (eg, pancreatitis, peritoneal carcinomatosis had a

  14. Social movement heterogeneity in public policy framing: A multi-stakeholder analysis of the Keystone XL pipeline

    Science.gov (United States)

    Wesley, David T. A.

    In 2011, stakeholders with differing objectives formed an alliance to oppose the Keystone XL heavy oil pipeline. The alliance, which came to be known as "Tar Sands Action," implemented various strategies, some of which were more successful than others. Tar Sands Action was a largely heterogeneous alliance that included indigenous tribes, environmentalists, ranchers, landowners, and trade unions, making it one of the more diverse social movement organizations in history. Each of these stakeholder categories had distinct demographic structures, representing an array of racial, ethnic, educational, occupational, and political backgrounds. Participants also had differing policy objectives that included combating climate change and protecting jobs, agricultural interests, water resources, wildlife, and human health. The current dissertation examines the Tar Sands Action movement to understand how heterogeneous social movement organizations mobilize supporters, maintain alliances, and create effective frames to achieve policy objectives. A multi-stakeholder analysis of the development, evolution and communication of frames concerning the Keystone XL controversy provides insight into the role of alliances, direct action, and the news media in challenging hegemonic frames. Previous research has ignored the potential value that SMO heterogeneity provides by treating social movements as culturally homogenous. However, diversity has been shown to affect performance in business organizations. The current study demonstrates that under some circumstances, diversity can also improve policy outcomes. Moreover, policy frames are shown to be more effective in sustaining news media and public interest through a process the author calls dynamic frame sequencing (DFS). DFS refers to a process implementing different stakeholder frames at strategically opportune moments. Finally, Tar Sands Action was one of the first SMOs to rely heavily on social media to build alliances, disseminate

  15. Preliminary results of BRAVO project: brain computer interfaces for Robotic enhanced Action in Visuo-motOr tasks.

    Science.gov (United States)

    Bergamasco, Massimo; Frisoli, Antonio; Fontana, Marco; Loconsole, Claudio; Leonardis, Daniele; Troncossi, Marco; Foumashi, Mohammad Mozaffari; Parenti-Castelli, Vincenzo

    2011-01-01

    This paper presents the preliminary results of the project BRAVO (Brain computer interfaces for Robotic enhanced Action in Visuo-motOr tasks). The objective of this project is to define a new approach to the development of assistive and rehabilitative robots for motor impaired users to perform complex visuomotor tasks that require a sequence of reaches, grasps and manipulations of objects. BRAVO aims at developing new robotic interfaces and HW/SW architectures for rehabilitation and regain/restoration of motor function in patients with upper limb sensorimotor impairment through extensive rehabilitation therapy and active assistance in the execution of Activities of Daily Living. The final system developed within this project will include a robotic arm exoskeleton and a hand orthosis that will be integrated together for providing force assistance. The main novelty that BRAVO introduces is the control of the robotic assistive device through the active prediction of intention/action. The system will actually integrate the information about the movement carried out by the user with a prediction of the performed action through an interpretation of current gaze of the user (measured through eye-tracking), brain activation (measured through BCI) and force sensor measurements. © 2011 IEEE

  16. Preliminary assessments the shortcut to remediation (category III-surplus facility assessments)

    International Nuclear Information System (INIS)

    Byars, L.L.

    1995-01-01

    This report presents the details of the preliminary assessments for the shortcut of decontamination of surplus nuclear facilities. Topics discussed include: environment, health and safety concerns; economic considerations; reduction of transition time; preliminary characterization reports; preliminary project plan; health and safety plan; quality assurance plan; surveillance and maintenance plan; and waste management plan

  17. LFQProfiler and RNP(xl): Open-Source Tools for Label-Free Quantification and Protein-RNA Cross-Linking Integrated into Proteome Discoverer.

    Science.gov (United States)

    Veit, Johannes; Sachsenberg, Timo; Chernev, Aleksandar; Aicheler, Fabian; Urlaub, Henning; Kohlbacher, Oliver

    2016-09-02

    Modern mass spectrometry setups used in today's proteomics studies generate vast amounts of raw data, calling for highly efficient data processing and analysis tools. Software for analyzing these data is either monolithic (easy to use, but sometimes too rigid) or workflow-driven (easy to customize, but sometimes complex). Thermo Proteome Discoverer (PD) is a powerful software for workflow-driven data analysis in proteomics which, in our eyes, achieves a good trade-off between flexibility and usability. Here, we present two open-source plugins for PD providing additional functionality: LFQProfiler for label-free quantification of peptides and proteins, and RNP(xl) for UV-induced peptide-RNA cross-linking data analysis. LFQProfiler interacts with existing PD nodes for peptide identification and validation and takes care of the entire quantitative part of the workflow. We show that it performs at least on par with other state-of-the-art software solutions for label-free quantification in a recently published benchmark ( Ramus, C.; J. Proteomics 2016 , 132 , 51 - 62 ). The second workflow, RNP(xl), represents the first software solution to date for identification of peptide-RNA cross-links including automatic localization of the cross-links at amino acid resolution and localization scoring. It comes with a customized integrated cross-link fragment spectrum viewer for convenient manual inspection and validation of the results.

  18. Corrosion of API XL 52 steel in presence of Clostridium celerecrescens

    Energy Technology Data Exchange (ETDEWEB)

    Monroy, O.A. Ramos; Ordaz, N. Ruiz; Ramirez, C. Juarez [Escuela Nacional de Ciencias Biologicas, Instituto Politecnico Nacional, Prolongacion de Carpio y Plan de Ayala, Mexico D. F., C. P. 11340 (Mexico); Gayosso, M.J. Hernandez; Olivares, G. Zavala [Instituto Mexicano del Petroleo, Grupo Corrosion, Eje Central Lazaro Cardenas 152, Col. San Bartolo Atepehuacan, Mexico D. F., C. P. 07730 (Mexico)

    2011-09-15

    During the characterization of sediments formed in pipelines transporting hydrocarbons, the knowledge of the microbiological diversity becomes very interesting, especially when it is related to microbiologically influenced corrosion (MIC). The presence of microorganisms is considered as one of the factors that affect the corrosion processes occurring at the pipeline; therefore, their corrosiveness must be determined. In this way, the identification of new species affecting the MIC processes is still considered relevant. In this work, the effect of Clostridium celerecrescens upon the corrosion of API KL 52 steel was evaluated. This microorganism was isolated and identified from the sediments collected during the inner cleaning procedures of a gas pipeline. The polarization resistance (PR) and electrochemical impedance spectroscopy (EIS) techniques were considered to estimate the microorganism behavior during the corrosion process. The results were complemented with a metal surface analysis, using a scanning electron microscope (SEM). The resistance values induced by the presence of the microorganisms clearly indicated that C. celerecrescens has an effect on the corrosion process occurring at the API XL 52 steel surface. (Copyright copyright 2011 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim)

  19. NEOLITHIC PLANT USE IN THE WESTERN MEDITERRANEAN REGION: PRELIMINARY RESULTS FROM THE AGRIWESTMED PROJECT

    Directory of Open Access Journals (Sweden)

    L. Peña-Chocarro

    2013-04-01

    Full Text Available This contribution focuses on the preliminary results of the AGRIWESTMED project which focuses on the archaeobotanical analyses of early Neolithic sites in the western Mediterranean region (both in Iberia and in northern Morocco. A large number of sites has been studied producing an interesting dataset of plant remains which places the earliest examples of domesticated plants in the second half of the 6th millennium cal BC. Plant diversity is high as it is shown by the large number of species represented: hulled and naked wheats, barley, peas, fava beans, vetches, lentils and grass peas. To more crops, poppy and flax, are also part of the first agricultural crops of the area. Although agriculture seems to occupy a first place in the production of food, gathering is well represented in the Moroccan sites where a large number of species has been identified. 

  20. Preliminary Analysis and Selection of Mooring Solution Candidates

    DEFF Research Database (Denmark)

    Thomsen, Jonas Bjerg; Delaney, Martin

    This report covers a preliminary analysis of mooring solutions candidates for four large floating wave energy converters. The work is part of the EUDP project “Mooring Solutions for Large Wave Energy Converters” and is the outcome of "Work Package 3: Preliminary Analysis". The report further...... compose the "Milestone 4: Report on results of preliminary analysis and selection of final candidates. The report is produced by Aalborg University with input from the partner WECs Floating Power Plant, KNSwing, LEANCON and Wave Dragon. Tension Technology International (TTI) has provided a significant...

  1. Preliminary safety evaluation for the spent nuclear fuel project`s cold vacuum drying system

    Energy Technology Data Exchange (ETDEWEB)

    Garvin, L.J., Westinghouse Hanford

    1996-07-01

    This preliminary safety evaluation (PSE) considers only the Cold Vacuum Drying System (CVDS) facility and its mission as it relates to the integrated process strategy (WHC 1995). The purpose of the PSE is to identify those CBDS design functions that may require safety- class and safety-significant accident prevention and mitigation features.

  2. Preliminary results from the ESA STSE project on SST diurnal variability, its regional extent and implications in atmospheric modelling (SSTDV:R.EX.–IM.A.M.)

    DEFF Research Database (Denmark)

    Karagali, Ioanna; Hasager, Charlotte Bay; Høyer, Jacob L.

    2013-01-01

    This study presents some preliminary results of the ESA Support To Science Element (STSE) funded project on the Diurnal Variability of the Sea Surface Temperature, regarding its Regional Extend and Implications in Atmospheric Modelling (SSTDV:R.EX.–IM.A.M.). Comparisons of SEVIRI SST with AATSR...

  3. Small hydro project in Wohlen, Bern - Preliminary study; Programm Kleinwasserkraftwerke. KWKW Hofenmuehle, Wohlen BE - Vorstudie

    Energy Technology Data Exchange (ETDEWEB)

    Fritschi, M.; Spescha, P.

    2008-11-15

    This report for the Swiss Federal Office of Energy (SFOE) presents the preliminary project study for the refurbishment of an existing small hydropower installation in Wohlen, Bern, Switzerland. The installation is in the Hofenmuehle, a listed mill complex dating from the first half of the nineteenth century. The headrace channel has already been refurbished by a community service group. The high level of financial effort and the idealism of the owner families are noted. The existing installations are described in detail. The refurbishment of the technical equipment and the associated work such as water-flow measurements are discussed. Cost estimates and environmental aspects are presented and discussed as are the financing of the refurbishment work and the cost-covering remuneration for the power produced. A possible increase in the power produced and the associated water-usage concession are discussed.

  4. Project Rulison: a preliminary report

    Energy Technology Data Exchange (ETDEWEB)

    Reynolds, M Jr; Bray, B G; Mann, R L

    1970-01-01

    Project Rulison was designed to use underground nuclear technology to determine the potential of this technique for commercial development of the deep, thick, lenticular, low permeability, Mesaverde Formation of the Tuli Rulison field in Garfield County, Colorado. A feasibility study completed in July 1966 indicated that nuclear explosives were a potentially economic method of stimulating recovery of natural gas from the reservoir. The gas-in-place, estimated to be between 90 to 125 billion cu ft per 640 acres from earlier wells, was confirmed from information obtained on 2 conventional wells completed in 1966. The Project Rulison exploratory well, R-EX, was completed in May 1968. Detailed testing of this well provided data on geology, hydrology and reservoir characteristics. The data obtained from the testing have been used to determine the flow capacity of the Mesaverde reservoir. The reservoir characteristics were then used as input data to make predictions of post-shot reservoir performance in the nuclear stimulated well, using a radial, unsteady state gas-flow computer model. (20 refs.)

  5. Malawi faith communities responding to HIV/AIDS: preliminary ...

    African Journals Online (AJOL)

    This paper reports on the preliminary findings (year one) of a four-year intervention and participatory-action research (PAR) project in Malawi. Project goals are to enhance the response capacity and effectiveness of faith community (FC) leaders to the problem of HIV/AIDS. Ethnographic interviews with FC leaders were ...

  6. 75 FR 77862 - FFP Missouri 16, LLC, Solia 9 Hydroelectric, LLC; Notice of Competing Preliminary Permit...

    Science.gov (United States)

    2010-12-14

    ... Missouri 16, LLC, Solia 9 Hydroelectric, LLC; Notice of Competing Preliminary Permit Applications Accepted.... On August 6, 2010, FFP Missouri 16, LLC (FFP) and Solia 9 Hydroelectric, LLC filed preliminary permit...-2822. Solia 9 Hydroelectric's proposed Lock and Dam 15 Hydropower Project (Project No. 13827-000) would...

  7. Cloning and expression analysis of genes encoding lytic endopeptidases L1 and L5 from Lysobacter sp. strain XL1.

    Science.gov (United States)

    Lapteva, Y S; Zolova, O E; Shlyapnikov, M G; Tsfasman, I M; Muranova, T A; Stepnaya, O A; Kulaev, I S; Granovsky, I E

    2012-10-01

    Lytic enzymes are the group of hydrolases that break down structural polymers of the cell walls of various microorganisms. In this work, we determined the nucleotide sequences of the Lysobacter sp. strain XL1 alpA and alpB genes, which code for, respectively, secreted lytic endopeptidases L1 (AlpA) and L5 (AlpB). In silico analysis of their amino acid sequences showed these endopeptidases to be homologous proteins synthesized as precursors similar in structural organization: the mature enzyme sequence is preceded by an N-terminal signal peptide and a pro region. On the basis of phylogenetic analysis, endopeptidases AlpA and AlpB were assigned to the S1E family [clan PA(S)] of serine peptidases. Expression of the alpA and alpB open reading frames (ORFs) in Escherichia coli confirmed that they code for functionally active lytic enzymes. Each ORF was predicted to have the Shine-Dalgarno sequence located at a canonical distance from the start codon and a potential Rho-independent transcription terminator immediately after the stop codon. The alpA and alpB mRNAs were experimentally found to be monocistronic; transcription start points were determined for both mRNAs. The synthesis of the alpA and alpB mRNAs was shown to occur predominantly in the late logarithmic growth phase. The amount of alpA mRNA in cells of Lysobacter sp. strain XL1 was much higher, which correlates with greater production of endopeptidase L1 than of L5.

  8. Performance of 2000CA/LL and 2260XL liquid scintillation spectrometers for low-level tritium and carbon-14 analyses

    International Nuclear Information System (INIS)

    Rozanski, K.; Stichler, W.; Schwarz, P.

    1991-01-01

    The performance of two commercially available liquid scintillation spectrometers for low-level counting of 3 H and 14 C has been investigated. Two models of new technology Tri-Carb spectrometers from the Packard Instrument Company were tested: the 2000CA/LL and 2260XL. The measurements revealed a superior 3 H performance of the 2000CA/LL equipment owing to its substantially higher counting efficiency. Results for 14 C are less conclusive and depend on the configuration of the counting parameters selected. A comparison of three commercially available scintillation cocktails for tritium assay in water samples revealed a superior performance for PicoFluor LLT. (Author)

  9. Preliminary results of radiation monitoring near uranium mines in Namibia EJOLT Project (DRAFT version)

    International Nuclear Information System (INIS)

    Chareyron, Bruno

    2012-01-01

    As a part of the EJOLT (Environmental Justice Organizations Liability and Trade) project, EARTHLIFE Namibia and CRIIRAD (Commission for Independent Research and Information about Radiation) have organised visits in areas located in the vicinity of uranium mines in Namibia In the course of an on site mission carried out between September 22 and October 2 2011, scientists from the CRIIRAD laboratory took radiation measurements in situ, and collected 14 samples of top soil, 13 samples of surface sediments of the Swakop, Gawib and Khan rivers, 11 underground water samples in the alluvium of Swakop, and Khan rivers and tap water from Arandis city, and one sample of asparagus. Solid samples have been analysed at the CRIIRAD laboratory in France (measurements performed by HpGe gamma spectrometry) and water samples have been monitored for main chemicals by LDA 26 laboratory in France and for radium 226 and radon 222 at the CRIIRAD laboratory. Some of the preliminary findings are summarised in this report: 1 - The dose rate measured by CRIIRAD on the parking of Roessing mine is about 6 times above natural background value (0.9 μSv/h compared to 0.15 μSv/h); 2 - The management of waste rock dumps needs to be improved: Some waste rocks are dumped on the banks of Khan river (at the intersection with Dome Gorge) without fencing and confinement. The radiological impact of this activity has to be studied in detail but preliminary measurements show various impacts on the environment; 3 - The finest fraction of the radioactive tailings dumped on Roessing tailings dam is blown away by the wind and contaminates the surrounding environment; 4 - The high uranium concentration in underground water collected downstream Roessing uranium mine in the Khan river and Swakop river alluvium raises the question of the origin of this uranium

  10. Preliminary results of radiation monitoring near uranium mines in Namibia EJOLT Project (DRAFT version)

    Energy Technology Data Exchange (ETDEWEB)

    Chareyron, Bruno

    2012-04-05

    As a part of the EJOLT (Environmental Justice Organizations Liability and Trade) project, EARTHLIFE Namibia and CRIIRAD (Commission for Independent Research and Information about Radiation) have organised visits in areas located in the vicinity of uranium mines in Namibia In the course of an on site mission carried out between September 22 and October 2 2011, scientists from the CRIIRAD laboratory took radiation measurements in situ, and collected 14 samples of top soil, 13 samples of surface sediments of the Swakop, Gawib and Khan rivers, 11 underground water samples in the alluvium of Swakop, and Khan rivers and tap water from Arandis city, and one sample of asparagus. Solid samples have been analysed at the CRIIRAD laboratory in France (measurements performed by HpGe gamma spectrometry) and water samples have been monitored for main chemicals by LDA 26 laboratory in France and for radium 226 and radon 222 at the CRIIRAD laboratory. Some of the preliminary findings are summarised in this report: 1 - The dose rate measured by CRIIRAD on the parking of Roessing mine is about 6 times above natural background value (0.9 {mu}Sv/h compared to 0.15 {mu}Sv/h); 2 - The management of waste rock dumps needs to be improved: Some waste rocks are dumped on the banks of Khan river (at the intersection with Dome Gorge) without fencing and confinement. The radiological impact of this activity has to be studied in detail but preliminary measurements show various impacts on the environment; 3 - The finest fraction of the radioactive tailings dumped on Roessing tailings dam is blown away by the wind and contaminates the surrounding environment; 4 - The high uranium concentration in underground water collected downstream Roessing uranium mine in the Khan river and Swakop river alluvium raises the question of the origin of this uranium

  11. Preliminary radiation shielding design for BOOMERANG

    International Nuclear Information System (INIS)

    Donahue, Richard J.

    2002-01-01

    Preliminary radiation shielding specifications are presented here for the 3 GeV BOOMERANG Australian synchrotron light source project. At this time the bulk shield walls for the storage ring and injection system (100 MeV Linac and 3 GeV Booster) are considered for siting purposes

  12. 49 CFR 611.13 - Overall project ratings.

    Science.gov (United States)

    2010-10-01

    ... Transportation Other Regulations Relating to Transportation (Continued) FEDERAL TRANSIT ADMINISTRATION... to enter into preliminary engineering, final design, or FFGAs. (c) These ratings will be used to: (1) approve advancement of a proposed project into preliminary engineering and final design; (2) Approve...

  13. Energy levels, radiative rates, and lifetimes for transitions in W XL

    International Nuclear Information System (INIS)

    Aggarwal, Kanti M.; Keenan, Francis P.

    2014-01-01

    Energy levels and radiative rates are reported for transitions in Br-like tungsten, W XL, calculated with the general-purpose relativistic atomic structure package (GRASP). Configuration interaction (CI) has been included among 46 configurations (generating 4215 levels) over a wide energy range up to 213 Ryd. However, for conciseness results are only listed for the lowest 360 levels (with energies up to ∼43 Ryd), which mainly belong to the 4s 2 4p 5 ,4s 2 4p 4 4d,4s 2 4p 4 4f,4s4p 6 ,4p 6 4d,4s4p 5 4d,4s 2 4p 3 4d 2 , and 4s 2 4p 3 4d4f configurations, and provided for four types of transitions, E1, E2, M1, and M2. Comparisons are made with existing (but limited) results. However, to fully assess the accuracy of our data, analogous calculations have been performed with the flexible atomic code, including an even larger CI than in GRASP. Our energy levels are estimated to be accurate to better than 0.02 Ryd, whereas results for radiative rates (and lifetimes) should be accurate to better than 20% for a majority of the strong transitions

  14. Preliminary project concerning the straw-fueled combined power-heat plant to be constructed at Glamsbjerg

    International Nuclear Information System (INIS)

    Gabriel, S.; Koch, T.

    1994-06-01

    Power and heat generation based on biomass gasification is of great importance due to its beneficial environmental effects and good economy. This report concerns a preliminary project on feasibility and problems of implementing a dual-purpose power plant, supplying both power and district heating to several schools, swimming pools and other public facilities at Glamsbjerg (Funen). The plant is to be based on thermal gasification (pyrolysis) of straw and use of the gas in a diesel engine. The diesels operate the power generator, and their waste heat should be utilized in the local district heating network. In order to establish a stable and flexible straw supply to the plant an evaluation of resources in the area has been carried out. Apart from straw-derived fuel the plant is planned to use natural gas for start and maintenance of the process. The prices of the combined plant and of the fuel processing are estimated in the report. (EG)

  15. Federal subsidies for preliminary studies for small-scale hydropower installations: degree of implementation of preliminary study projects 1993-2001 - Short evaluation of the effect of federal subsidies; Bundesbeitraege an Vorstudien fuer Kleinwasserkraftwerke. Realisierungsstand der Vorstudienprojekte 1993 bis 2001. Kurzevaluation der Auswirkungen der Bundesbeitraege (1996)

    Energy Technology Data Exchange (ETDEWEB)

    Kuster, J.; Suter, Ph.

    2002-07-01

    This final report for the Swiss Federal Office of Energy (SFOE) presents the results of a short survey of 70 projects that received support from the Swiss Federation during their preliminary study phases. Projects are reviewed for the period between 1993 and 2001. The results obtained from the survey are presented; these are considered by the authors to be well-founded as a result of the high questionnaire return rate of 84%. The report analyses the projects as far as their degree of realisation is concerned and discusses the results. The survey also provides information on the power produced by those installations that have already been realised. For those projects that were not realised, the reasons for the negative investment decision are noted. Projects that are in the process of being implemented are discussed.

  16. Binding and preclusive effect of part-construction permits and preliminary licenses

    International Nuclear Information System (INIS)

    Jarass, H.D.

    1983-01-01

    This contribution discusses the binding and preclusive effect of part-construction permits and preliminary licenses granted in accordance with the laws on air pollution abatement and the Atomic Energy Act. The author states that the granting of a part-construction permit must be based on a final decision over the entire project and must include a preliminary judgement and evaluation of the entire project, also covering site selection and design concept approval. The binding effort and preclusive effect of part-permits are examined in great detail, namely their definition, basic principles, extent, coming into force and term of validity and, (for the preclusive effect), its prerequisites, consequences, considerations regarding immediate execution). The author concludes by stating that there is no difference in regard to binding or preclusive effect between part-construction permits and a preliminary licence. (HP) [de

  17. SNF sludge treatment system preliminary project execution plan

    International Nuclear Information System (INIS)

    Flament, T.A.

    1998-01-01

    The Fluor Daniel Hanford, Inc. (FDH) Project Director for the Spent Nuclear Fuel (SNF) Project has requested Numatec Hanford Company (NHC) to define how Hanford would manage a new subproject to provide a process system to receive and chemically treat radioactive sludge currently stored in the 100 K Area fuel retention basins. The subproject, named the Sludge Treatment System (STS) Subproject, provides and operates facilities and equipment to chemically process K Basin sludge to meet Tank Waste Remediation System (TWRS) requirements. This document sets forth the NHC management approach for the STS Subproject and will comply with the requirements of the SNF Project Management Plan (HNF-SD-SNFPMP-011). This version of this document is intended to apply to the initial phase of the subproject and to evolve through subsequent revision to include all design, fabrication, and construction conducted on the project and the necessary management and engineering functions within the scope of the subproject. As Project Manager, NHC will perform those activities necessary to complete the STS Subproject within approved cost and schedule baselines and turn over to FDH facilities, systems, and documentation necessary for operation of the STS

  18. Review of the Environmental Protection Agency’s Common Sense Initiative (The National Shipbuilding Research Program)

    Science.gov (United States)

    1996-03-01

    desired end product of this Work would be a “customer-oriented” research and development strategy for the industy Description of Project: The workgroup is...EPA as they implement EPA programs that have been delegated to them. EPA is taking a decentralized or “ franchising ” approach to the implementation of XL...PROJECT XL FEDERAL REGISTER NOTICE PUBLISHED MAY 22,1995 proposal; reviewing the proposal through respondent management; and consulting in some fashion

  19. FULL SCALE BIOREACTOR LANDFILL FOR CARBON SEQUESTRATION AND GREENHOUSE EMISSION CONTROL

    International Nuclear Information System (INIS)

    Ramin Yazdani; Jeff Kieffer; Heather Akau

    2002-01-01

    The Yolo County Department of Planning and Public Works is constructing a full-scale bioreactor landfill as a part of the Environmental Protection Agency's (EPA) Project XL program to develop innovative approaches while providing superior environmental protection. The overall objective is to manage landfill solid waste for rapid waste decomposition, maximum landfill gas generation and capture, and minimum long-term environmental consequences. Waste decomposition is accelerated by improving conditions for either the aerobic or anaerobic biological processes and involves circulating controlled quantities of liquid (leachate, groundwater, gray water, etc.), and, in the aerobic process, large volumes of air. The first phase of the project entails the construction of a 12-acre module that contains a 6-acre anaerobic cell, a 3.5-acre anaerobic cell, and a 2.5-acre aerobic cell at the Yolo County Central Landfill near Davis, California. The cells are highly instrumented to monitor bioreactor performance. The current project status and preliminary monitoring results are summarized in this report

  20. Preliminary safety analysis report for the TFTR

    International Nuclear Information System (INIS)

    Lind, K.E.; Levine, J.D.; Howe, H.J.

    A Preliminary Safety Analysis Report has been prepared for the Tokamak Fusion Test Reactor. No accident scenarios have been identified which would result in exposures to on-site personnel or the general public in excess of the guidelines defined for the project by DOE

  1. The IAHR project CCHE-Climate Change impact on the Hydrological cycle, water management and Engineering: an overview and preliminary results

    Science.gov (United States)

    Ranzi, Roberto; Kojiri, T.; Mynett, A.; Barontini, S.; van de Giesen, N.; Kolokytha, E.; Ngo, L. A.; Oreamuno, R.; Renard, B.; Sighomnou, D.; Vizina, A.

    2010-05-01

    IAHR, the International Association for Hydro-Environment Engineering and Research launched a research Project called Climate Change impact on the Hydrological cycle, water management and Engineering (IAHR CCHE Project). It was motivated by the fact that, although it is now well accepted that, in the light of the recent IPCC reports the vast majority of members of the scientific community are convinced that the climate is changing or at least will experience a significant fluctuation already during the current century, it is perceived that some hydrologists, water experts and hydraulic engineers are not yet ready to incorporate climate change scenarios in their designs for such projects as: - flood protection and river training, - dam rehabilitation, - water resources management under water scarcity and changes in the hydrological regimes. The objective of the project is to encourage a close co-operation between the scientific and engineering communities in taking appropriate and timely action in response to the impact of climate change on the hydrological regime and on water resource projects. The project aims at reporting on (a) the current state of knowledge as regards the impact of projected climate change on the hydrological regime in different regions of the world, where these regions are defined not just in geographic terms but also on the basis of their level of economic and water resources development; (b) the extent to which these impacts are recognized and taken into account by national water authorities, engineering organizations and other regulating bodies in setting their standard practices and procedures for the planning, design and operation of water works. These adaptation measures will include both "hard" responses, such as the construction or enlargement of engineering structures, and "soft" responses, such as changes in legislation or the operating rules of existing structures. An overview of the project and preliminary results extracted from of

  2. Infrastructure Joint Venture Projects in Malaysia: A Preliminary Study

    Science.gov (United States)

    Romeli, Norsyakilah; Muhamad Halil, Faridah; Ismail, Faridah; Sufian Hasim, Muhammad

    2018-03-01

    As many developed country practise, the function of the infrastructure is to connect the each region of Malaysia holistically and infrastructure is an investment network projects such as transportation water and sewerage, power, communication and irrigations system. Hence, a billions allocations of government income reserved for the sake of the infrastructure development. Towards a successful infrastructure development, a joint venture approach has been promotes by 2016 in one of the government thrust in Construction Industry Transformation Plan which encourage the internationalisation among contractors. However, there is depletion in information on the actual practise of the infrastructure joint venture projects in Malaysia. Therefore, this study attempt to explore the real application of the joint venture in Malaysian infrastructure projects. Using the questionnaire survey, a set of survey question distributed to the targeted respondents. The survey contained three section which the sections are respondent details, organizations background and project capital in infrastructure joint venture project. The results recorded and analyse using SPSS software. The contractors stated that they have implemented the joint venture practice with mostly the client with the usual construction period of the infrastructure project are more than 5 years. Other than that, the study indicates that there are problems in the joint venture project in the perspective of the project capital and the railway infrastructure should be given a highlights in future study due to its high significant in term of cost and technical issues.

  3. Infrastructure Joint Venture Projects in Malaysia: A Preliminary Study

    Directory of Open Access Journals (Sweden)

    Romeli Norsyakilah

    2018-01-01

    Full Text Available As many developed country practise, the function of the infrastructure is to connect the each region of Malaysia holistically and infrastructure is an investment network projects such as transportation water and sewerage, power, communication and irrigations system. Hence, a billions allocations of government income reserved for the sake of the infrastructure development. Towards a successful infrastructure development, a joint venture approach has been promotes by 2016 in one of the government thrust in Construction Industry Transformation Plan which encourage the internationalisation among contractors. However, there is depletion in information on the actual practise of the infrastructure joint venture projects in Malaysia. Therefore, this study attempt to explore the real application of the joint venture in Malaysian infrastructure projects. Using the questionnaire survey, a set of survey question distributed to the targeted respondents. The survey contained three section which the sections are respondent details, organizations background and project capital in infrastructure joint venture project. The results recorded and analyse using SPSS software. The contractors stated that they have implemented the joint venture practice with mostly the client with the usual construction period of the infrastructure project are more than 5 years. Other than that, the study indicates that there are problems in the joint venture project in the perspective of the project capital and the railway infrastructure should be given a highlights in future study due to its high significant in term of cost and technical issues.

  4. Meeting of the ITER CTA Project Board

    International Nuclear Information System (INIS)

    Vlasenkov, V.

    2001-01-01

    The meeting of the ITER CTA Project Board took place in Toronto, Canada on 7 November 2001, on the occasion of the first Negotiations Meeting. Twelve participants, representing PB members and experts from Canada, the EU, Japan, the RF and the international Team (IT), attended the meeting chaired by Acad. E. Velikhov. Discussions on the preliminary work programme for the CTA and organizational arrangements for the IT and PT took most of the time of the meeting. The Project Board approved the preliminary work programme as presented by the IT leader

  5. Structural variations and dielectric properties of (Bi1-xL ax ) 2Si O5 (0 ≤x ≤0.1 ): Polycrystallines synthesized by crystallization of Bi-Si-O and Bi-La-Si-O glasses

    Science.gov (United States)

    Taniguchi, Hiroki; Tatewaki, Shingo; Yasui, Shintaro; Fujii, Yasuhiro; Yamaura, Jun-ichi; Terasaki, Ichiro

    2018-04-01

    This paper focuses on effects of isovalent La substitution on the crystal structure and dielectric properties of ferroelectric B i2Si O5 . Polycrystalline samples of (Bi1-xL ax ) 2Si O5 are synthesized by crystallization of Bi-Si-O and Bi-La-Si-O glasses with a composition range of 0 ≤x ≤0.1 . The crystal structure changes from monoclinic to tetragonal with increasing La-substitution rate x at room temperature. This structural variation stems from the change in orientation of Si O4 tetrahedra that form one-dimensional chains when they are in the ordered configuration, thus suggesting that lone-pair electrons play an important role in sustaining one-dimensional chains of Si O4 tetrahedra. Synchronizing with the disordering of Si O4 chains, ferroelectric phase transition temperature of (Bi1-xL ax ) 2Si O5 sharply decreases as x increases, and ferroelectricity finally vanishes at around x =0.03 . The present results demonstrate that lone-pair electrons of Bi play an important role in the ferroelectricity of B i2Si O5 through propping the ordered structure of one-dimensional Si O4 chains with stereochemical activity. Furthermore, an additional phase transition has been first discovered in the low-temperature region of (Bi1-xL ax ) 2Si O5 with x ≤0.01 , where the ordered one-dimensional Si O4 chains remain.

  6. Permitted Marine Hydrokinetic Projects

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This data represents pending or issued preliminary permits or issued licenses for marine hydrokinetic projects that produce energy from waves or directly from the...

  7. Preliminary assessment of potential CDM early start projects in Brazil

    Energy Technology Data Exchange (ETDEWEB)

    Meyers, S.; Sathaye, J.; Lehman, B.; Schumacher, K.; van Vliet, O.; Moreira, J.R.

    2000-11-01

    The Brazil/US Aspen Global Forum on Climate Change Policies and Programs has facilitated a dialogue between key Brazil and US public and private sector leaders on the subject of the Clean Development Mechanism (CDM). With support from the US government, a cooperative effort between Lawrence Berkeley National Laboratory and the University of Sao Paulo conducted an assessment of a number of projects put forth by Brazilian sponsors. Initially, we gathered information and conducted a screening assessment for ten projects in the energy sector and six projects in the forestry sector. Some of the projects appeared to offer greater potential to be attractive for CDM, or had better information available. We then conducted a more detailed assessment of 12 of these projects, and two other projects that were submitted after the initial screening. An important goal was to assess the potential impact of Certified Emission Reductions (CERs) on the financial performance of projects. With the exception of the two forestry-based fuel displacement projects, the impact of CERs on the internal rate of return (IRR) is fairly small. This is true for both the projects that displace grid electricity and those that displace local (diesel-based) electricity production. The relative effect of CERs is greater for projects whose IRR without CERs is low. CERs have a substantial effect on the IRR of the two short-rotation forestry energy substitution projects. One reason is that the biofuel displaces coke and oil, both of which are carbon-intensive. Another factor is that the product of these projects (charcoal and woodfuel, respectively) is relatively low value, so the revenue from carbon credits has a strong relative impact. CERs also have a substantial effect on the NPV of the carbon sequestration projects. Financial and other barriers pose a challenge for implementation of most of the projects. In most cases, the sponsor lacks sufficient capital, and loans are available only at high interest

  8. Cathodic protection of XL 52 steel under the influence of sulfate reducing bacteria

    Energy Technology Data Exchange (ETDEWEB)

    Esquivel, R. Garcia [Instituto Mexicano del Petroleo, Eje Central Lazaro Cardenas No. 152, Col. San Bartolo Atepehuacan, Mexico, D.F. 07730 (Mexico); Departamento de lngenieria Metalurgica, Facultad de Quimica, Universidad Nacional Autonoma de Mexico, Ciudad Universitaria, 04510 Mexico, D.F. (Mexico); Olivares, G. Zavala; Gayosso, M.J. Hernandez; Trejo, A. Gayosso [Instituto Mexicano del Petroleo, Eje Central Lazaro Cardenas No. 152, Col. San Bartolo Atepehuacan, Mexico, D.F. 07730 (Mexico)

    2011-01-15

    The effect of sulfate reducing bacteria (SRB) upon the cathodic protection of XL 52 steel was determined, in order to identify if the potential value of -0.950 V versus copper/copper sulfate electrode is good enough to protect the metal surface. During the experiments, different operational parameters were monitored: hydrogen sulfide production, iron concentration, electrolyte alkalinity, microorganisms' population, as well as the metal surface damage. At the same time, the corrosion rate was determined using two electrochemical techniques: polarization resistance (PR) and electrochemical impedance spectroscopy (EIS). According to the results, it was observed that the protection potential of -0.950 V versus copper/copper sulfate electrode is not enough to control the microbiologically induced corrosion. This situation is reinforced by the fact that significant iron concentration was found in the electrolyte. The microbiological activity is not affected by the protection potential. On the contrary, the population growth is slightly strengthened. The alkalinity generated by the applied potential did not stop the SRB growth. A type of localized corrosion was developed during the experiments with microorganisms, even when the protection potential was applied to the system. (Copyright copyright 2011 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim)

  9. Halonium Ions as Halogen Bond Donors in the Solid State [XL2]Y Complexes.

    Science.gov (United States)

    Rissanen, Kari; Haukka, Matti

    2015-01-01

    The utilization of halogen bonding interactions is one of the most rapidly developing areas of supramolecular chemistry. While the other weak non-covalent interactions and their influence on the structure and chemistry of various molecules, complexes, and materials have been investigated extensively, the understanding, utilizations, and true nature of halogen bonding are still relatively unexplored. Thus its final impact in chemistry in general and in materials science has not yet been fully established. Because of the polarized nature of a Z-X bond (Z=electron-withdrawing atom or moiety and X=halogen atom), such a moiety can act as halogen bond donor when the halogen is polarized enough by the atom/moiety Z. The most studied and utilized halogen bond donor molecules are the perfluorohalocarbons, where Z is a perfluorinated aryl or alkyl moiety and X is either iodine or bromine. Complementing the contemporary halogen bonding research, this chapter reviews the solid state structural chemistry of the most extremely polarized halogen atoms, viz. halonium ions, X+, and discussed them as halogen bond donors in the solid state [XL2]Y complexes (X=halonium ion, Y=any anion).

  10. 76 FR 6459 - Mahoning Hydropower, LLC; Notice of Preliminary Permit Application Accepted for Filing and...

    Science.gov (United States)

    2011-02-04

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Project No. 13954-000] Mahoning Hydropower, LLC; Notice of Preliminary Permit Application Accepted for Filing and Soliciting Comments... Hydropower, LLC filed an application for a preliminary permit, pursuant to section 4(f) of the Federal Power...

  11. 76 FR 7838 - Mahoning Hydropower, LLC; Notice of Preliminary Permit Application Accepted for Filing and...

    Science.gov (United States)

    2011-02-11

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Project No. 13953-000] Mahoning Hydropower, LLC; Notice of Preliminary Permit Application Accepted for Filing and Soliciting Comments... Hydropower, LLC filed an application for a preliminary permit, pursuant to section 4(f) of the Federal Power...

  12. Preliminary Development of a Work Breakdown Structure (WBS) for Small Modular Reactors (SMRs)

    Energy Technology Data Exchange (ETDEWEB)

    Harrison, Thomas J [ORNL; Moses, Rebecca J [ORNL; Flanagan, George F [ORNL

    2014-10-01

    In summary, this preliminary WBS serves as an initial basis for the capital cost component of the economic analysis of SMRs. This preliminary WBS comes from the known WBS for existing, large nuclear power plants and develops the methodology for accounting for the anticipated differences between the current large plants and the projected SMR designs.

  13. The Mixed Waste Management Facility. Preliminary design review

    International Nuclear Information System (INIS)

    1995-01-01

    This document presents information about the Mixed Waste Management Facility. Topics discussed include: cost and schedule baseline for the completion of the project; evaluation of alternative options; transportation of radioactive wastes to the facility; capital risk associated with incineration; radioactive waste processing; scaling of the pilot-scale system; waste streams to be processed; molten salt oxidation; feed preparation; initial operation to demonstrate selected technologies; floorplans; baseline revisions; preliminary design baseline; cost reduction; and project mission and milestones

  14. 75 FR 59706 - Coastal Hydropower, LLC; Notice of Preliminary Permit Application Accepted for Filing and...

    Science.gov (United States)

    2010-09-28

    ... Hydropower, LLC; Notice of Preliminary Permit Application Accepted for Filing and Soliciting Comments... on July 16, 2010, Coastal Hydropower, LLC filed an application for a preliminary permit, pursuant to... generation of the project would be 7.9 gigawatt-hours. Applicant Contact: Neil Anderson, Coastal Hydropower...

  15. Space Elevators Preliminary Architectural View

    Science.gov (United States)

    Pullum, L.; Swan, P. A.

    Space Systems Architecture has been expanded into a process by the US Department of Defense for their large scale systems of systems development programs. This paper uses the steps in the process to establishes a framework for Space Elevator systems to be developed and provides a methodology to manage complexity. This new approach to developing a family of systems is based upon three architectural views: Operational View OV), Systems View (SV), and Technical Standards View (TV). The top level view of the process establishes the stages for the development of the first Space Elevator and is called Architectural View - 1, Overview and Summary. This paper will show the guidelines and steps of the process while focusing upon components of the Space Elevator Preliminary Architecture View. This Preliminary Architecture View is presented as a draft starting point for the Space Elevator Project.

  16. Preliminary design report for the prototypical fuel rod consolidation system

    International Nuclear Information System (INIS)

    Rosa, J.M.

    1986-01-01

    This report documents NUTECH's preliminary design of a dry, spent fuel rod consolidation system. This preliminary design is the result of Phase I of a planned four phase project. The present report on this project provides a considerable amount of detail for a preliminary design effort. The design and all of its details are described in this Preliminary Design Report (PDR). The NUTECH dry rod consolidation system described herein is remotely operated. It provides for automatic operation, but with operator hold points between key steps in the process. The operator has the ability to switch to a manual operation mode at any point in the process. The system is directed by the operator using an executive computer which controls and coordinates the operation of the in-cell equipment. The operator monitors the process using an in-cell closed circuit television (CCTV) system with audio output and equipment status displays on the computer monitor. The in-cell mechanical equipment consists of the following: (1) two overhead cranes with manipulators; (2) a multi-degree of freedom fuel handling table and its clamping equipment; (3) a fuel assembly end fitting removal station and its tools; (4) a consolidator (which pulls rods, assembles the consolidated bundle and loads the canister); (5) a canister end cap welder and weld inspection system; (6) decontamination systems; and (7) the CCTV and microphone systems

  17. Preliminary design of a coffee harvester

    Directory of Open Access Journals (Sweden)

    Raphael Magalhães Gomes Moreira

    2016-10-01

    Full Text Available Design of an agricultural machine is a highly complex process due to interactions between the operator, machine, and environment. Mountain coffee plantations constitute an economic sector that requires huge investments for the development of agricultural machinery to improve the harvesting and post-harvesting processes and to overcome the scarcity of work forces in the fields. The aim of this study was to develop a preliminary design for a virtual prototype of a coffee fruit harvester. In this study, a project methodology was applied and adapted for the development of the following steps: project planning, informational design, conceptual design, and preliminary design. The construction of a morphological matrix made it possible to obtain a list of different mechanisms with specific functions. The union between these mechanisms resulted in variants, which were weighed to attribute scores for each selected criterion. From each designated proposal, two variants with the best scores were selected and this permitted the preparation of the preliminary design of both variants. The archetype was divided in two parts, namely the hydraulically articulated arms and the harvesting system that consisted of the vibration mechanism and the detachment mechanism. The proposed innovation involves the use of parallel rods, which were fixed in a plane and rectangular metal sheet. In this step, dimensions including a maximum length of 4.7 m, a minimum length of 3.3 m, and a total height of 2.15 m were identified based on the functioning of the harvester in relation to the coupling point of the tractor.

  18. Analisis Pengaruh Stres Kerja, Beban Kerja dan Lingkungan Kerja terhadap Turnover Intention Karyawan pada PT XL Axiata Tbk Jakarta

    Directory of Open Access Journals (Sweden)

    Laksmi Sito Dwi Irvianti

    2015-05-01

    Full Text Available This study aims to determine the effect of job stress, workload and work environment to employee turnover intention PT XL Axiata Tbk Jakarta. This study used survey research and data collection technique used are observation, interviews, literature studies and questionnaires distributed through 81 employees as respondents. The collected data was analyzed by using simple and multiple regression. From the research, it is known variables X1 (job stress partially influence on the variable Y (turnover intention. The X2 variable (workload partially influence variable Y (turnover intention. While the X3 variable (work environment partially influence variable Y (turnover intention And unknown variables X1 (job stress, X2 (workload and X3 (work environment influences variable Y (turnover intention simultaneously.

  19. Yucca Mountain transportation routes: Preliminary characterization and risk analysis

    International Nuclear Information System (INIS)

    Souleyrette, R.R. II; Sathisan, S.K.; di Bartolo, R.

    1991-01-01

    This report presents appendices related to the preliminary assessment and risk analysis for high-level radioactive waste transportation routes to the proposed Yucca Mountain Project repository. Information includes data on population density, traffic volume, ecologically sensitive areas, and accident history

  20. Preliminary design review report for K Basin Dose Reduction Project

    International Nuclear Information System (INIS)

    Blackburn, L.D.

    1996-01-01

    The strategy for reducing radiation dose, originating from radionuclides absorbed in the K East Basin concrete, is to raise the pool water level to provide additional shielding. This report documents a preliminary design review conducted to ensure that design approaches for cleaning/coating basin walls and modifying other basin components were appropriate. The conclusion of this review was that design documents presently conclusion of this review was that design documents presently completed or in process of modification are and acceptable basis for proceeding to complete the design

  1. OSU TOMF Program Site Selection and Preliminary Concept Design Report

    Energy Technology Data Exchange (ETDEWEB)

    Spadling, Steve [Oklahoma State Univ., Stillwater, OK (United States)

    2012-05-10

    The purpose of this report is to confirm the programmatic requirements for the new facilities, identify the most appropriate project site, and develop preliminary site and building concepts that successfully address the overall project goals and site issues. These new facilities will be designed to accommodate the staff, drivers and maintenance requirements for the future mixed fleet of passenger vehicles, Transit Style Buses and School Buses.

  2. Utility of Social Modeling for Proliferation Assessment - Preliminary Assessment

    Energy Technology Data Exchange (ETDEWEB)

    Coles, Garill A.; Gastelum, Zoe N.; Brothers, Alan J.; Thompson, Sandra E.

    2009-06-01

    This Preliminary Assessment draft report will present the results of a literature search and preliminary assessment of the body of research, analysis methods, models and data deemed to be relevant to the Utility of Social Modeling for Proliferation Assessment research. This report will provide: 1) a description of the problem space and the kinds of information pertinent to the problem space, 2) a discussion of key relevant or representative literature, 3) a discussion of models and modeling approaches judged to be potentially useful to the research, and 4) the next steps of this research that will be pursued based on this preliminary assessment. This draft report represents a technical deliverable for the NA-22 Simulations, Algorithms, and Modeling (SAM) program. Specifically this draft report is the Task 1 deliverable for project PL09-UtilSocial-PD06, Utility of Social Modeling for Proliferation Assessment. This project investigates non-traditional use of social and cultural information to improve nuclear proliferation assessment, including nonproliferation assessment, proliferation resistance assessments, safeguards assessments and other related studies. These assessments often use and create technical information about the State’s posture towards proliferation, the vulnerability of a nuclear energy system to an undesired event, and the effectiveness of safeguards. This project will find and fuse social and technical information by explicitly considering the role of cultural, social and behavioral factors relevant to proliferation. The aim of this research is to describe and demonstrate if and how social science modeling has utility in proliferation assessment.

  3. 78 FR 5798 - Ceresco Hydroelectric Dam, LLC; Notice of Preliminary Permit Application Accepted for Filing and...

    Science.gov (United States)

    2013-01-28

    ... Hydroelectric Dam, LLC; Notice of Preliminary Permit Application Accepted for Filing and Soliciting Comments, Motions To Intervene, and Competing Applications On October 19, 2012, Ceresco Hydroelectric Dam, LLC...), proposing to study the feasibility of the Ceresco Hydroelectric Project (Ceresco Project or project) to be...

  4. Social construction and physical nihilation of the Keystone XL pipeline: Lessons from international relations theory

    International Nuclear Information System (INIS)

    Shum, Robert Y.

    2013-01-01

    If a prime goal of energy policy is to achieve energy security, why is there a controversy over the proposed Keystone XL pipeline, designed to deliver new supplies of oil from within North America? This Viewpoint seeks answers in the debate over the underlying purposes of energy policy: how does one answers the question “what do we want from energy policy?” Perceptions of feasible answers and policy options change over time, as witnessed in the 1970s. Analogous shifts in opinion are changing today's policy debates and widening the contradictions in policy purposes. Attention to the existence of these contradictions, without illusions, is necessary to meet the policy challenges of the future effectively. - Highlights: • We apply international relations theory to explain the persistence of the Keystone controversy. • Key question relates to policy purposes: “what do we want from energy policy?” • Alternative purposes: maximizing economic growth or ensuring environmental sustainability. • 1970s US cases show how perceptions of each purpose's relative feasibility shift. • Different purposes generate different attitudes to policies that result in higher oil prices

  5. 77 FR 10739 - SV Hydro, LLC, Coffeeville, LLC, FFP Project 99, LLC; Notice Announcing Preliminary Permit Drawing

    Science.gov (United States)

    2012-02-23

    ... Announcing Preliminary Permit Drawing . The Commission has received three preliminary permit applications... Commission, or her designee, will conduct a random drawing to determine the filing priority of the applicants... section 4.37 of its regulations.\\3\\ The priority established by this drawing will be used to determine...

  6. Teletandem between French and Brazilian students: Some preliminary remarks

    Directory of Open Access Journals (Sweden)

    Liliane SANTOS

    2015-12-01

    Full Text Available ABSTRACT In its French-Brazilian version, the Teletandem Brazil project enables students from the University of Lille 3 (France and from the State University of São Paulo (Unesp, Brazil, to take part in online exchanges, based on the principles of autonomy and reciprocity. In this work, we will present some preliminary remarks on the construction of cultural identity representations by the students who took part in the project, from 2006 to 2012, the specificity of the exchanges we analyze being that most of the French students involved in them are third generation Portuguese. We will examine the consequences of the introduction of a third culture within exchanges which, linguistically speaking, are bilateral. The French students are often experiencing conflicting feelings toward Brazil and, similarly, the Brazilian students may have conflicting feelings towards Portugal and France. Our preliminary results show that the most successful linguistic exchanges occur when students face their own cultural identity with no feeling of superiority or inferiority.

  7. An Overview of the International H2O Project (IHOP_2002) and Some Preliminary Highlights.

    Science.gov (United States)

    Weckwerth, Tammy M.; Parsons, David B.; Koch, Steven E.; Moore, James A.; Lemone, Margaret A.; Demoz, Belay B.; Flamant, Cyrille; Geerts, Bart; Wang, Junhong; Feltz, Wayne F.

    2004-02-01

    The International H2O Project (IHOP_2002) is one of the largest North American meteorological field experiments in history. From 13 May to 25 June 2002, over 250 researchers and technical staff from the United States, Germany, France, and Canada converged on the Southern Great Plains to measure water vapor and other atmospheric variables. The principal objective of IHOP_2002 is to obtain an improved characterization of the time-varying three-dimensional water vapor field and evaluate its utility in improving the understanding and prediction of convective processes. The motivation for this objective is the combination of extremely low forecast skill for warm-season rainfall and the relatively large loss of life and property from flash floods and other warm-season weather hazards. Many prior studies on convective storm forecasting have shown that water vapor is a key atmospheric variable that is insufficiently measured. Toward this goal, IHOP_2002 brought together many of the existing operational and new state-of-the-art research water vapor sensors and numerical models.The IHOP_2002 experiment comprised numerous unique aspects. These included several instruments fielded for the first time (e.g., reference radiosonde); numerous upgraded instruments (e.g., Wyo-ming Cloud Radar); the first ever horizontal-pointing water vapor differential absorption lidar (DIAL; i.e., Leandre II on the Naval Research Laboratory P-3), which required the first onboard aircraft avoidance radar; several unique combinations of sensors (e.g., multiple profiling instruments at one field site and the German water vapor DIAL and NOAA/Environmental Technology Laboratory Doppler lidar on board the German Falcon aircraft); and many logistical challenges. This article presents a summary of the motivation, goals, and experimental design of the project, illustrates some preliminary data collected, and includes discussion on some potential operational and research implications of the experiment.

  8. Kemper County IGCC (tm) Project Preliminary Public Design Report

    Energy Technology Data Exchange (ETDEWEB)

    Nelson, Matt; Rush, Randall; Madden, Diane; Pinkston, Tim; Lunsford, Landon

    2012-07-01

    The Kemper County IGCC Project is an advanced coal technology project that is being developed by Mississippi Power Company (MPC). The project is a lignite-fueled 2-on-1 Integrated Gasification Combined-Cycle (IGCC) facility incorporating the air-blown Transport Integrated Gasification (TRIG™) technology jointly developed by Southern Company; Kellogg, Brown, and Root (KBR); and the United States Department of Energy (DOE) at the Power Systems Development Facility (PSDF) in Wilsonville, Alabama. The estimated nameplate capacity of the plant will be 830 MW with a peak net output capability of 582 MW. As a result of advanced emissions control equipment, the facility will produce marketable byproducts of ammonia, sulfuric acid, and carbon dioxide. 65 percent of the carbon dioxide (CO{sub 2}) will be captured and used for enhanced oil recovery (EOR), making the Kemper County facility’s carbon emissions comparable to those of a natural-gas-fired combined cycle power plant. The commercial operation date (COD) of the Kemper County IGCC plant will be May 2014. This report describes the basic design and function of the plant as determined at the end of the Front End Engineering Design (FEED) phase of the project.

  9. Small-scale hydro power in the Anniviers Valley. Project Chippis-Ricard. Variants and preliminary project; Forces Motrices de la Gougra SA. Mini-hydraulique en Anniviers. Projet Chippis-Ricard. Etude de variantes et avant-projet

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2008-04-15

    This report for the Swiss Federal Office of Energy (SFOE) reports on the preliminary project for a small hydropower plant in Chippis, Switzerland. The project takes advantage of an existing irrigation scheme that deviates water from the Navisence River into two successive tunnels (total 1.8 km) and a following channel built on steep mountain sides. The basic idea of the project is to increase the flow rate entering the tunnels from 265 l/s to 1265 l/s and to lead the additional 1000 l/s to a new penstock connected to the second tunnel's outlet. In this way, a hydraulic head of 130 m could be used for power generation for over 600 households (mechanical power: 0.8 to 1.1 MW, annual electrical energy production: 2.5 to 3.6 GWh, depending on the variant considered). The report reviews the history of water use at this location and its present use as well as a feasibility study previously made. The project is described, including water collection points, conduits, the power station and the particular aspects of the joint use of water for power generation and irrigation from mid April to mid September. Technical details on water quantities and energy production are presented. Financial aspects including construction and operating costs are presented and the economic viability of the project is discussed. Environmental aspects are reviewed. Further steps to be taken in the realisation of this hydropower installation are listed.

  10. Knowledge Model: Project Knowledge Management

    DEFF Research Database (Denmark)

    Durao, Frederico; Dolog, Peter; Grolin, Daniel

    2009-01-01

    The Knowledge model for project management serves several goals:Introducing relevant concepts of project management area for software development (Section 1). Reviewing and understanding the real case requirements from the industrial perspective. (Section 2). Giving some preliminary suggestions...... for usage in KIWI system (Sections 3). This document is intended for technological partners to understand how for example the software development concepts can be applied to a semantic wiki framework....

  11. 77 FR 5506 - ORPC Maine, LLC; Notice of Preliminary Permit Application Accepted for Filing and Soliciting...

    Science.gov (United States)

    2012-02-03

    ... preliminary permit, pursuant to section 4(f) of the Federal Power Act (FPA), proposing to study the feasibility of the Treat Island Tidal Energy Project to be located in Passamaquoddy Bay, between the Town of Eastport and Treat Island, Washington County, Maine. The sole purpose of a preliminary permit, if issued...

  12. High-performance instruments in neutron arena of JHP. Preliminary version

    International Nuclear Information System (INIS)

    Furusaka, M.; Itoh, S.; Otomo, T.; Arai, M.

    1996-05-01

    This report is a preliminary report of high-performance instruments in neutron arena of JHP (Japan Hadron Project). This report consists of as follows; neutron intensity of neutron arena, development of neutron sources in neutron arena, experimental devices and instrumentation. (J.P.N.)

  13. El Paso County Geothermal Project at Fort Bliss. Final Project Report

    Energy Technology Data Exchange (ETDEWEB)

    Lear, Jon [Ruby Mountain Inc., Salt Lake City, UT (United State); Bennett, Carlon [Ruby Mountain Inc., Salt Lake City, UT (United State); Lear, Dan [Ruby Mountain Inc., Salt Lake City, UT (United State); Jones, Phil L. [Ruby Mountain Inc., Salt Lake City, UT (United State); Burdge, Mark [Evergreen Clean Energy Management, Provo, UT (United States); Barker, Ben [Evergreen Clean Energy Management, Provo, UT (United States); Segall, Marylin [Univ. of Utah, Salt Lake City, UT (United States). Energy and Geoscience Inst.; Moore, Joseph [Univ. of Utah, Salt Lake City, UT (United States). Energy and Geoscience Inst.; Nash, Gregory [Univ. of Utah, Salt Lake City, UT (United States). Energy and Geoscience Inst.; Jones, Clay [Univ. of Utah, Salt Lake City, UT (United States). Energy and Geoscience Inst.; Simmons, Stuart [Univ. of Utah, Salt Lake City, UT (United States). Energy and Geoscience Inst.; Taylor, Nancy [Univ. of Utah, Salt Lake City, UT (United States). Energy and Geoscience Inst.

    2016-02-01

    The El Paso County Geothermal Project at Fort Bliss was an effort to determine the scale and scope of geothermal resources previously identified on Fort Bliss’ McGregor Range in southern Otero County, New Mexico. The project was funded with a $5,000,000 grant to El Paso County from the U.S. Department of Energy (DOE) as part of the American Recovery and Reinvestment Act of 2009 and a $4,812,500 match provided by private sector partners. The project was administered through the DOE Golden Field Office to awardee El Paso County. The primary subcontractor to El Paso County and project Principal Investigator - Ruby Mountain Inc. (RMI) of Salt Lake City, Utah - assembled the project team consisting of Evergreen Clean Energy Management (ECEM) of Provo, Utah, and the Energy & Geoscience Institute at the University of Utah (EGI) in Salt Lake City, UT to complete the final phases of the project. The project formally began in May of 2010 and consisted of two preliminary phases of data collection and evaluation which culminated in the identification of a drilling site for a Resource Confirmation Well on McGregor Range. Well RMI 56-5 was drilled May and June 2013 to a depth of 3,030 ft. below ground level. A string of slotted 7 inch casing was set in 8.75 inch hole on bottom fill at 3,017 ft. to complete the well. The well was drilled using a technique called flooded reverse circulation, which is most common in mineral exploration. This technique produced an exceptionally large and complete cuttings record. An exciting development at the conclusion of drilling was the suspected discovery of a formation that has proven to be of exceptionally high permeability in three desalinization wells six miles to the south. Following drilling and preliminary testing and analysis, the project team has determined that the McGregor Range thermal anomaly is large and can probably support development in the tens of megawatts.

  14. Research reactor job analysis - A project description

    International Nuclear Information System (INIS)

    Yoder, John; Bessler, Nancy J.

    1988-01-01

    Addressing the need of the improved training in nuclear industry, nuclear utilities established training program guidelines based on Performance-Based Training (PBT) concepts. The comparison of commercial nuclear power facilities with research and test reactors owned by the U.S. Department of Energy (DOE), made in an independent review of personnel selection, training, and qualification requirements for DOE-owned reactors pointed out that the complexity of the most critical tasks in research reactors is less than that in power reactors. The U.S. Department of Energy (DOE) started a project by commissioning Oak Ridge Associated Universities (ORAU) to conduct a job analysis survey of representative research reactor facilities. The output of the project consists of two publications: Volume 1 - Research Reactor Job Analysis: Overview, which contains an Introduction, Project Description, Project Methodology,, and. An Overview of Performance-Based Training (PBT); and Volume 2 - Research Reactor Job Analysis: Implementation, which contains Guidelines for Application of Preliminary Task Lists and Preliminary Task Lists for Reactor Operators and Supervisory Reactor Operators

  15. 78 FR 37217 - Ted P. Sorenson; Notice of Preliminary Permit Application Accepted for Filing and Soliciting...

    Science.gov (United States)

    2013-06-20

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Project No. 14519-000] Ted P. Sorenson; Notice of Preliminary Permit Application Accepted for Filing and Soliciting Comments, Motions To Intervene, and Competing Applications On May 1, 2013, Ted P. Sorenson filed an application for a preliminary permit, pursuant to section 4(f) of the...

  16. 77 FR 12280 - FFP Missouri 17, LLC BOST2 Hydroelectric, LLC; Notice Announcing Filing Priority for Preliminary...

    Science.gov (United States)

    2012-02-29

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Project Nos. 13824-000, 13826-000] FFP Missouri 17, LLC BOST2 Hydroelectric, LLC; Notice Announcing Filing Priority for Preliminary Permit... Hydroelectric, LLC, Project No. 13826-000. 2. FFP Missouri 17, LLC, Project No. 13824-000. Dated: February 22...

  17. Students' Entrepreneurial Inclination at a Malaysian Polytechnic: A Preliminary Investigation

    Science.gov (United States)

    Yasin, Ahmad Yasruddin Md; Mahmood, Nik Abdul Aziz Nik; Jaafar, Nik Azyyati Nik

    2011-01-01

    This paper reports preliminary results of an ongoing project to examine students' inclination towards entrepreneurship at a Malaysian polytechnic. The study used a self-administered questionnaire to explore the influence of entrepreneurial intent, perceived behavioral control, self-efficacy, perceived barriers, perceived support factors and…

  18. Preliminary results from NOAMP deep drifting floats

    International Nuclear Information System (INIS)

    Ollitrault, M.

    1989-01-01

    This paper is a very brief and preliminary outline of first results obtained with deep SOFAR floats in the NOAMP area. The work is now going toward more precise statistical estimations of mean and variable currents, together with better tracking to resolve submesoscales and estimate diffusivities due to mesoscale and smaller scale motions. However the preliminary results confirm that the NOAMP region (and surroundings) has a deep mesoscale eddy field that is considerably more energetic that the mean field (r.m.s. velocities are of order 5 cm s -1 ), although both values are diminished compared to the western basin. A data report containing trajectories and statistics is scheduled to be published by IFREMER in the near future. The project main task is to especially study the dispersion of radioactive substances

  19. Preliminary site characterization radiological monitoring plan for the Nevada Nuclear Waste Storage Investigations Project, Yucca Mountain Site

    International Nuclear Information System (INIS)

    1987-03-01

    The activities described in this plan occur in the early phases of site characterization. This document presents the Preliminary Site Characterization Radiological Monitoring Plan (PSCRMP) for collecting and evaluating data in support of the NNWSI Project. The PSCRMP defines and identifies control procedures for the monitoring activities. The PSCRMP activity will utilize integrating radon monitoring devices, a continuous radon monitor, and a particulate air sampler. These instruments will be used to establish the baseline radioactivity and/or radioactivity released due to early site characterization activities. The sections that follow provide a general project description, the specifics of the monitoring program, and the practices that will be employed to ensure the validity of the collected data by integrating quality assurance into all activities. Section 2 of this document describes the regulatory base of this document. Section 3 describes the site characterization activities which may lead to release of radioactivity. Section 4 provides a description of the potential sources of radioactivity that site characterization could generate. Section 5 summarizes the sampling and monitoring methodology, which will be used to monitor the potential sources of radioactivity. The network of sampling and monitoring equipment is described in Section 6, and Section 7 summarizes the systems operation activities. The data reporting activities are described in Section 8. Finally, a description of the Quality Assurance (QA) and Quality Control (QC) activities is provided in Section 9. Appendix A contains a summary of the procedures to be used in this program, and Appendix B contains technical specification on equipment and services. 20 refs., 11 figs., 2 tabs

  20. Understanding the costs and schedule of hydroelectric projects

    International Nuclear Information System (INIS)

    Merrow, E.W.; Schroeder, B.R.

    1991-01-01

    This paper is based on a study conducted for the World Bank which evaluated the feasibility of developing an empirically based ex ante project analysis system for hydroelectric projects. The system would be used to assess: the reasonableness of engineering-based cost and schedule estimates used for project appraisal and preliminary estimates used to select projects for appraisal; and the potential for cost growth and schedule slip. The system would help identify projects early in the project appraisal process that harbor significantly higher than normal risks of overrunning cost and schedule estimates

  1. Conceptual Design Plan SM-43 Replacement Project

    Energy Technology Data Exchange (ETDEWEB)

    University of California, Los Alamos National Laboratory, SCC Project Office

    2000-11-01

    The Los Alamos National Laboratory Conceptual Design Plan for the SM-43 Replacement Project outlines plans for replacing the SM-43 Administration Building. Topics include the reasons that replacement is considered a necessity; the roles of the various project sponsors; and descriptions of the proposed site and facilities. Also covered in this proposal is preliminary information on the project schedule, cost estimates, acquisition strategy, risk assessment, NEPA strategy, safety strategy, and safeguards and security. Spreadsheets provide further detail on space requirements, project schedules, and cost estimates.

  2. 77 FR 31843 - Swan Lake North Hydro, LLC; Notice of Preliminary Permit Application Accepted For Filing and...

    Science.gov (United States)

    2012-05-30

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Project No. 13318-002] Swan Lake North Hydro, LLC; Notice of Preliminary Permit Application Accepted For Filing and Soliciting Comments, Motions to Intervene, and Competing Applications On April 3, 2012, Swan Lake North Hydro, LLC, filed an application for a successive preliminary permit...

  3. Independent management and financial review, Yucca Mountain Project, Nevada. Final report, Appendix

    International Nuclear Information System (INIS)

    1995-01-01

    The Nuclear Waste Policy Act of 1982 (Public Law 97-425), as amended by Public Law 100-203, December 22, 1987, established the Office of Civilian Radioactive Waste Management (OCRWM) within the Department of Energy (DOE), and directed the Office to investigate a site at Yucca Mountain, Nevada, to determine if this site is suitable for the construction of a repository for the disposal of high level nuclear waste. Work on site characterization has been under way for several years. Thus far, about $1.47 billion have been spent on Yucca Mountain programs. This work has been funded by Congressional appropriations from a Nuclear Waste Fund to which contributions have been made by electric utility ratepayers through electric utilities generating power from nuclear power stations. The Secretary of Energy and the Governor of the State of Nevada have appointed one person each to a panel to oversee an objective, independent financial and management evaluation of the Yucca Mountain Project. The Requirements for the work will include an analysis of (1) the Yucca Mountain financial and, contract management techniques and controls; (2) Project schedules and credibility of the proposed milestones; (3) Project organizational effectiveness and internal planning processes, and (4) adequacy of funding levels and funding priorities, including the cost of infrastructure and scientific studies. The recipient will provide monthly progress report and the following reports/documents will be presented as deliverables under the contract: (1) Financial and Contract Management Preliminary Report; (2) Project Scheduling Preliminary Report; (3)Project Organizational Effectiveness Preliminary Report; (4) Project Funding Levels and Funding Priorities Preliminary Report; and (5) Final Report

  4. Independent management and financial review, Yucca Mountain Project, Nevada. Final report, Appendix

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-07-15

    The Nuclear Waste Policy Act of 1982 (Public Law 97-425), as amended by Public Law 100-203, December 22, 1987, established the Office of Civilian Radioactive Waste Management (OCRWM) within the Department of Energy (DOE), and directed the Office to investigate a site at Yucca Mountain, Nevada, to determine if this site is suitable for the construction of a repository for the disposal of high level nuclear waste. Work on site characterization has been under way for several years. Thus far, about $1.47 billion have been spent on Yucca Mountain programs. This work has been funded by Congressional appropriations from a Nuclear Waste Fund to which contributions have been made by electric utility ratepayers through electric utilities generating power from nuclear power stations. The Secretary of Energy and the Governor of the State of Nevada have appointed one person each to a panel to oversee an objective, independent financial and management evaluation of the Yucca Mountain Project. The Requirements for the work will include an analysis of (1) the Yucca Mountain financial and, contract management techniques and controls; (2) Project schedules and credibility of the proposed milestones; (3) Project organizational effectiveness and internal planning processes, and (4) adequacy of funding levels and funding priorities, including the cost of infrastructure and scientific studies. The recipient will provide monthly progress report and the following reports/documents will be presented as deliverables under the contract: (1) Financial and Contract Management Preliminary Report; (2) Project Scheduling Preliminary Report; (3)Project Organizational Effectiveness Preliminary Report; (4) Project Funding Levels and Funding Priorities Preliminary Report; and (5) Final Report.

  5. 76 FR 50726 - Riverbank Hydro No. 14, LLC; Notice of Preliminary Permit Application Accepted for Filing and...

    Science.gov (United States)

    2011-08-16

    ... (FPA), proposing to study the feasibility of the Tuttle Creek Hydroelectric Project (Tuttle Creek Project or project) to be located at the U.S. Army Corps of Engineers' (Corps) Tuttle Creek Dam, on Big Blue River, near Manhattan, Riley County, Kansas. The sole purpose of a preliminary permit, if issued...

  6. Renewable energy projects in the Dominican Republic

    Energy Technology Data Exchange (ETDEWEB)

    Viani, B.

    1997-12-01

    This paper describes a US/Dominican Republic program to develop renewable energy projects in the country. The objective is to demonstrate the commercial viability of renewable energy generation projects, primarily small-scale wind and hydropower. Preliminary studies are completed for three micro-hydro projects with a total capacity of 262 kWe, and two small wind power projects for water pumping. In addition wind resource assessment is ongoing, and professional training and technical assistance to potential investors is ongoing. Projects goals include not less than ten small firms actively involved in installation of such systems by September 1998.

  7. Managing a big ground-based astronomy project: the Thirty Meter Telescope (TMT) project

    Science.gov (United States)

    Sanders, Gary H.

    2008-07-01

    TMT is a big science project and its scale is greater than previous ground-based optical/infrared telescope projects. This paper will describe the ideal "linear" project and how the TMT project departs from that ideal. The paper will describe the needed adaptations to successfully manage real world complexities. The progression from science requirements to a reference design, the development of a product-oriented Work Breakdown Structure (WBS) and an organization that parallels the WBS, the implementation of system engineering, requirements definition and the progression through Conceptual Design to Preliminary Design will be summarized. The development of a detailed cost estimate structured by the WBS, and the methodology of risk analysis to estimate contingency fund requirements will be summarized. Designing the project schedule defines the construction plan and, together with the cost model, provides the basis for executing the project guided by an earned value performance measurement system.

  8. Agile Project Portfolio Management

    DEFF Research Database (Denmark)

    Andersen, Jesper Rank; Riis, Jens Ove; Mikkelsen, Hans

    2005-01-01

    This paper will provide a preliminary introduction to the application of Agile Thinking in management of project portfolio and company development. At any point in time, companies have a crowd of development initiatives spread around the organisation and managed at different levels...... in the managerial hierarchy. They compete for resources and managerial attention, and they often take too long time - and some do not survive in the rapid changing context. Top man¬agers ask for speed, flexibility and effectiveness in the portfolio of development activities (projects). But which competencies...

  9. Permitting of Landfill Bioreactor Operations: Ten Years after the RD&D Rule

    Science.gov (United States)

    Prior to promulgation of the Rule, there were approximately 20 full-scale bioreactor projects in North America, including one in Canada. Of these, six were permitted by EPA (four Project XL sites and two projects listed separately under a cooperative research agreement at the Ou...

  10. FY 1991 project plan for the Hanford Environmental Dose Reconstruction Project, Phase 2

    International Nuclear Information System (INIS)

    1991-02-01

    Phase 1 of the Hanford Environmental Dose Reconstruction Project was designed to develop and demonstrate a method for estimating radiation doses people may have received from Hanford Site operations since 1944. The method researchers developed relied on a variety of measured and reconstructed data as input to a modular computer model that generates dose estimates and their uncertainties. As part of Phase 1, researchers used the reconstructed data and computer model to calculate preliminary dose estimates for populations in a limited geographical area and time period. Phase 2, now under way, is designed to evaluate the Phase 1 data and model and improve them to calculate more accurate and precise dose estimates. Phase 2 will also be used to obtain preliminary estimates of two categories of doses: for Native American tribes and for individuals included in the pilot phase of the Hanford Thyroid Disease Study (HTDS). TSP Directive 90-1 required HEDR staff to develop Phase 2 task plans for TSP approval. Draft task plans for Phase 2 were submitted to the TSP at the October 11--12, 1990 public meeting, and, after discussions of each activity and associated budget needs, the TSP directed HEDR staff to proceed with a slate of specific project activities for FY 1991 of Phase 2. This project plan contains detailed information about those activities. Phase 2 is expected to last 15--18 months. In mid-FY 1991, project activities and budget will be reevaluated to determine whether technical needs or priorities have changed. Separate from, but related to, this project plan, will be an integrated plan for the remainder of the project. HEDR staff will work with the TSP to map out a strategy that clearly describes ''end products'' for the project and the work necessary to complete them. This level of planning will provide a framework within which project decisions in Phases 2, 3, and 4 can be made

  11. SolarOil Project, Phase I preliminary design report. [Solar Thermal Enhanced Oil Recovery project

    Energy Technology Data Exchange (ETDEWEB)

    Baccaglini, G.; Bass, J.; Neill, J.; Nicolayeff, V.; Openshaw, F.

    1980-03-01

    The preliminary design of the Solar Thermal Enhanced Oil Recovery (SolarOil) Plant is described in this document. This plant is designed to demonstrate that using solar thermal energy is technically feasible and economically viable in enhanced oil recovery (EOR). The SolarOil Plant uses the fixed mirror solar concentrator (FMSC) to heat high thermal capacity oil (MCS-2046) to 322/sup 0/C (611/sup 0/F). The hot fluid is pumped from a hot oil storage tank (20 min capacity) through a once-through steam generator which produces 4.8 MPa (700 psi) steam at 80% quality. The plant net output, averaged over 24 hr/day for 365 days/yr, is equivalent to that of a 2.4 MW (8.33 x 10/sup 6/ Btu/hr) oil-fired steam generator having an 86% availability. The net plant efficiency is 57.3% at equinox noon, a 30%/yr average. The plant will be demonstrated at an oilfield site near Oildale, California.

  12. Preliminary Assessment of JERS-1 SAR to Discriminating Boreal Landscape Features for the Boreal Forest Mapping Project

    Science.gov (United States)

    McDonald, Kyle; Williams, Cynthia; Podest, Erika; Chapman, Bruce

    1999-01-01

    This paper presents an overview of the JERS-1 North American Boreal Forest Mapping Project and a preliminary assessment of JERS-1 SAR imagery for application to discriminating features applicable to boreal landscape processes. The present focus of the JERS-1 North American Boreal Forest Mapping Project is the production of continental scale wintertime and summertime SAR mosaics of the North American boreal forest for distribution to the science community. As part of this effort, JERS-1 imagery has been collected over much of Alaska and Canada during the 1997-98 winter and 1998 summer seasons. To complete the mosaics, these data will be augmented with data collected during previous years. These data will be made available to the scientific community via CD ROM containing these and similar data sets compiled from companion studies of Asia and Europe. Regional landscape classification with SAR is important for the baseline information it will provide about distribution of woodlands, positions of treeline, current forest biomass, distribution of wetlands, and extent of major rivercourses. As well as setting the stage for longer term change detection, comparisons across several years provides additional baseline information about short-term landscape change. Rapid changes, including those driven by fire, permafrost heat balance, flooding, and insect outbreaks can dominate boreal systems. We examine JERS-1 imagery covering selected sites in Alaska and Canada to assess quality and applicability to such relevant ecological and hydrological issues. The data are generally of high quality and illustrate many potential applications. A texture-based classification scheme is applied to selected regions to assess the applicability of these data for distinguishing distribution of such landcover types as wetland, tundra, woodland and forested landscapes.

  13. Assessing the potential of wind energy projects. Notes for developers

    International Nuclear Information System (INIS)

    1999-11-01

    The objective of this publication is to provide some initial guidance for people who may be considering installing a wind power project. It sets out some key points which should be considered in a preliminary feasibility study and economic assessment of a project. (author)

  14. Integrated monitoring and surveillance system demonstration project: Phase I accomplishments

    International Nuclear Information System (INIS)

    Aumeier, S.E.; Walters, B.G.; Crawford, D.C.

    1997-01-01

    The authors present the results of the Integrated Monitoring and Surveillance System (IMSS) demonstration project Phase I efforts. The rationale behind IMSS development is reviewed and progress in each of the 5 basic tasks is detailed. Significant results include decisions to use Echelon LonWorks networking protocol and Microsoft Access for the data system needs, a preliminary design for the plutonium canning system glovebox, identification of facilities and materials available for the demonstration, determination of possibly affected facility documentation, and a preliminary list of available sensor technologies. Recently imposed changes in the overall project schedule and scope are also discussed and budgetary requirements for competition of Phase II presented. The results show that the IMSS demonstration project team has met and in many cases exceeded the commitments made for Phase I deliverables

  15. Simplified methods and application to preliminary design of piping for elevated temperature service

    International Nuclear Information System (INIS)

    Severud, L.K.

    1975-01-01

    A number of simplified stress analysis methods and procedures that have been used on the FFTF project for preliminary design of piping operating at elevated temperatures are described. The rationale and considerations involved in developing the procedures and preliminary design guidelines are given. Applications of the simplified methods to a few FFTF pipelines are described and the success of these guidelines are measured by means of comparisons to pipeline designs that have had detailed Code type stress analyses. (U.S.)

  16. [Efficiency of computer-based documentation in long-term care--preliminary project].

    Science.gov (United States)

    Lüngen, Markus; Gerber, Andreas; Rupprecht, Christoph; Lauterbach, Karl W

    2008-06-01

    In Germany the documentation of processes in long-term care is mainly paper-based. Planning, realization and evaluation are not supported in an optimal way. In a preliminary study we evaluated the consequences of the introduction of a computer-based documentation system using handheld devices. We interviewed 16 persons before and after introducing the computer-based documentation and assessed costs for the documentation process and administration. The results show that reducing costs is likely. The job satisfaction of the personnel increased, more time could be spent for caring for the residents. We suggest further research to reach conclusive results.

  17. Heat recovery and seed recovery development project: preliminary design report (PDR)

    Energy Technology Data Exchange (ETDEWEB)

    Arkett, A. H.; Alexander, K. C.; Bolek, A. D.; Blackman, B. K.; Kurrle, P. E.; Tram, S. V.; Warren, A. M.; Ziobrowski, A. J.

    1981-06-01

    The preliminary design and performance characteristics are described of the 20 MWt heat recovery and seed recovery (HRSR) system to be fabricated, installed, and evaluated to provide a technological basis for the design of commercial size HRSR systems for coal-fired open-cycle MHD power plants. The system description and heat and material balances, equipment description and functional requirements, controls, interfacing systems, and operation and maintenance are detailed. Appendices include: (1) recommended environmental requirements for compliance with federal and state of Tennessee regulations, (2) channel and diffuser simulator, (3) equipment arrangement drawings, and (4) channel and diffuser simulator barrel drawings. (WHK)

  18. Trade-off results and preliminary designs of Near-Term Hybrid Vehicles

    Science.gov (United States)

    Sandberg, J. J.

    1980-01-01

    Phase I of the Near-Term Hybrid Vehicle Program involved the development of preliminary designs of electric/heat engine hybrid passenger vehicles. The preliminary designs were developed on the basis of mission analysis, performance specification, and design trade-off studies conducted independently by four contractors. THe resulting designs involve parallel hybrid (heat engine/electric) propulsion systems with significant variation in component selection, power train layout, and control strategy. Each of the four designs is projected by its developer as having the potential to substitute electrical energy for 40% to 70% of the petroleum fuel consumed annually by its conventional counterpart.

  19. Current Mooring Design in Partner WECs and Candidates for Preliminary Analysis

    DEFF Research Database (Denmark)

    Thomsen, Jonas Bjerg; Ferri, Francesco; Kofoed, Jens Peter

    This report is the combined report of Commercial Milestone "CM1: Design and Cost of Current Mooring Solutions of Partner WECs" and Milestone "M3: Mooring Solutions for Preliminary Analysis" of the EUDP project "Mooring Solutions for Large Wave Energy Converters". The report covers a description o...

  20. Tri-State Synfuels Project Review: Volume 12. Fluor project status. [Proposed Henderson, Kentucky coal to gasoline plant; engineering

    Energy Technology Data Exchange (ETDEWEB)

    1982-06-01

    The purpose of this report is to document and summarize activities associated with Fluor's efforts on the Tri-State Synfuels Project. The proposed facility was to be coal-to-transport fuels facility located in Henderson, Kentucky. Tri-State Synfuels Company was participating in the project as a partner of the US Department of Energy per terms of a Cooperative Agreement resulting from DOE's synfuel's program solicitation. Fluor's initial work plan called for preliminary engineering and procurement services to the point of commitment for construction for a Sasol Fischer-Tropsch plant. Work proceeded as planned until October 1981 when results of alternative coal-to-methanol studies revealed the economic disadvantage of the Synthol design for US markets. A number of alternative process studies followed to determine the best process configuration. In January 1982 Tri-State officially announced a change from Synthol to a Methanol to Gasoline (MTG) design basis. Further evaluation and cost estimates for the MTG facility eventually led to the conclusion that, given the depressed economic outlook for alternative fuels development, the project should be terminated. Official announcement of cancellation was made on April 13, 1982. At the time of project cancellation, Fluor had completed significant portions of the preliminary engineering effort. Included in this report are descriptions and summaries of Fluor's work during this project. In addition location of key project data and materials is identified and status reports for each operation are presented.

  1. Licensing support system preliminary needs analysis: Volume 1

    International Nuclear Information System (INIS)

    1989-01-01

    This Preliminary Needs Analysis, together with the Preliminary Data Scope Analysis (next in this series of reports), is a first effort under the LSS Design and Implementation Contract toward developing a sound requirements foundation for subsequent design work. Further refinements must be made before requirements can be specified in sufficient detail to provide a basis for suitably specific system specifications. This preliminary analysis of the LSS requirements has been divided into a ''needs'' and a ''data scope'' portion only for project management and scheduling reasons. The Preliminary Data Scope Analysis will address all issues concerning the content and size of the LSS data base; providing the requirements basis for data acquisition, cataloging and storage sizing specifications. This report addresses all other requirements for the LSS. The LSS consists of both computer subsystems and non-computer archives. This study addresses only the computer subsystems, focusing on the Access Subsystems. After providing background on previous LSS-related work, this report summarizes the findings from previous examinations of needs and describes a number of other requirements that have an impact on the LSS. The results of interviews conducted for this report are then described and analyzed. The final section of the report brings all of the key findings together and describes how these needs analyses will continue to be refined and utilized in on-going design activities. 14 refs., 2 figs., 1 tab

  2. Liberalism, Communitarianism and the Project of Self | van der ...

    African Journals Online (AJOL)

    In this article the authors seek to conceptualize a dynamic and inclusive understanding of personal identity within multicultural democracies such as South Africa, which will draw on both the liberal and communitarian traditions' respect for the project of self. A preliminary lay out for such a project emerges from a literature ...

  3. U.S. LCI Database Project--Final Phase I Report

    Energy Technology Data Exchange (ETDEWEB)

    2003-08-01

    This Phase I final report reviews the process and provides a plan for the execution of subsequent phases of the database project, including recommended data development priorities and a preliminary cost estimate. The ultimate goal of the project is to develop publicly available LCI Data modules for commonly used materials, products, and processes.

  4. 75 FR 2127 - Basin Farm Renewable, LLC; Notice of Preliminary Permit Application Accepted for Filing and...

    Science.gov (United States)

    2010-01-14

    ... Renewable, LLC; Notice of Preliminary Permit Application Accepted for Filing and Soliciting Comments... Renewable, LLC filed an application, pursuant to section 4(f) of the Federal Power Act, proposing to study the feasibility of the Basin Farm Renewable Energy Project Project, to be located on Saxtons River, in...

  5. Revisiting EOR Projects in Indonesia through Integrated Study: EOR Screening, Predictive Model, and Optimisation

    KAUST Repository

    Hartono, A. D.; Hakiki, Farizal; Syihab, Z.; Ambia, F.; Yasutra, A.; Sutopo, S.; Efendi, M.; Sitompul, V.; Primasari, I.; Apriandi, R.

    2017-01-01

    EOR preliminary analysis is pivotal to be performed at early stage of assessment in order to elucidate EOR feasibility. This study proposes an in-depth analysis toolkit for EOR preliminary evaluation. The toolkit incorporates EOR screening, predictive, economic, risk analysis and optimisation modules. The screening module introduces algorithms which assimilates statistical and engineering notions into consideration. The United States Department of Energy (U.S. DOE) predictive models were implemented in the predictive module. The economic module is available to assess project attractiveness, while Monte Carlo Simulation is applied to quantify risk and uncertainty of the evaluated project. Optimization scenario of EOR practice can be evaluated using the optimisation module, in which stochastic methods of Genetic Algorithms (GA), Particle Swarm Optimization (PSO) and Evolutionary Strategy (ES) were applied in the algorithms. The modules were combined into an integrated package of EOR preliminary assessment. Finally, we utilised the toolkit to evaluate several Indonesian oil fields for EOR evaluation (past projects) and feasibility (future projects). The attempt was able to update the previous consideration regarding EOR attractiveness and open new opportunity for EOR implementation in Indonesia.

  6. Revisiting EOR Projects in Indonesia through Integrated Study: EOR Screening, Predictive Model, and Optimisation

    KAUST Repository

    Hartono, A. D.

    2017-10-17

    EOR preliminary analysis is pivotal to be performed at early stage of assessment in order to elucidate EOR feasibility. This study proposes an in-depth analysis toolkit for EOR preliminary evaluation. The toolkit incorporates EOR screening, predictive, economic, risk analysis and optimisation modules. The screening module introduces algorithms which assimilates statistical and engineering notions into consideration. The United States Department of Energy (U.S. DOE) predictive models were implemented in the predictive module. The economic module is available to assess project attractiveness, while Monte Carlo Simulation is applied to quantify risk and uncertainty of the evaluated project. Optimization scenario of EOR practice can be evaluated using the optimisation module, in which stochastic methods of Genetic Algorithms (GA), Particle Swarm Optimization (PSO) and Evolutionary Strategy (ES) were applied in the algorithms. The modules were combined into an integrated package of EOR preliminary assessment. Finally, we utilised the toolkit to evaluate several Indonesian oil fields for EOR evaluation (past projects) and feasibility (future projects). The attempt was able to update the previous consideration regarding EOR attractiveness and open new opportunity for EOR implementation in Indonesia.

  7. Notification: Preliminary Research on EPA's Design for the Environment Product Labeling Program OIG

    Science.gov (United States)

    Project #OPE-FY14-4012, November 06, 2013. The Office of Inspector General (OIG) is starting preliminary research on the U.S. Environmental Protection Agency’s (EPA’s) Design for the Environment (DfE) Product Labeling Program.

  8. Central Arkansas Energy Project. Coal to medium-Btu gas

    Science.gov (United States)

    1982-05-01

    The Central Arkansas Energy Project has as its objective the conversion of coal in a central location to a more readily usable energy source, medium Btu gas (MBG), for use at dispersed locations as fuel for power production and steam generation, or as a feedstock for chemical processing. The project elements consist of a gasification facility to produce MBG from coal, a pipeline to supply the MBG to the dispersed sites. The end of line users investigated were the repowering or refueling of an existing Arkansas Power and Light Co. Generating station, an ammonia plant, and a combined cycle cogeneration facility for the production of steam and electricity. Preliminary design of the gasification plant including process engineering design bases, process flow diagrams, utility requirements, system description, project engineering design, equipment specifications, plot plan and section plot plans, preliminary piping and instrument diagrams, and facilities requirements. Financial analyses and sensitivities are determined. Design and construction schedules and manpower loadings are developed. It is concluded that the project is technically feasible, but the financial soundness is difficult to project due to uncertainty in energy markets of competing fuels.

  9. Preliminary reports on fiscal 2000 results of project for subsidizing international joint research; 2000 nendo kokusai kyodo kenkyu josei jigyo seika hokoku kai yokoshu

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-12-01

    This paper presents preliminary reports on fiscal 2000 results of project for subsidizing international joint research sponsored by NEDO. For international joint research teams doing excellent studies, their research expenses are subsidized, thereby promoting international research exchange, enhancing international level of industrial technology and contributing to the formation of basis for innovative industrial technology. The projects relating to the global environmental field are implemented jointly with RITE. The contents of the report to be published are, in the global environmental field (practicability study), development of oil substitute resources, reproducible resources, and technologies for producing polymeric and plastic materials benign to the earth by microorganism using carbon dioxide. In the substance/material field, the contents of the report are innovative production and device application of tunable photonic crystals using electronic penetration network; development of new synthesis process of innovative nitride, creation and theoretical calculation of electromagnetic function; studies on quantum transportation in superconductor and semiconductor bonding structures; and studies on quantum liquid and solid, and application to materials science and technology. (NEDO)

  10. Valproic acid inhibits neural progenitor cell death by activation of NF-κB signaling pathway and up-regulation of Bcl-XL

    Directory of Open Access Journals (Sweden)

    Han Seol

    2011-07-01

    Full Text Available Abstract Background At the beginning of neurogenesis, massive brain cell death occurs and more than 50% of cells are eliminated by apoptosis along with neuronal differentiation. However, few studies were conducted so far regarding the regulation of neural progenitor cells (NPCs death during development. Because of the physiological role of cell death during development, aberration of normal apoptotic cell death is detrimental to normal organogenesis. Apoptosis occurs in not only neuron but also in NPCs and neuroblast. When growth and survival signals such as EGF or LIF are removed, apoptosis is activated as well as the induction of differentiation. To investigate the regulation of cell death during developmental stage, it is essential to investigate the regulation of apoptosis of NPCs. Methods Neural progenitor cells were cultured from E14 embryonic brains of Sprague-Dawley rats. For in vivo VPA animal model, pregnant rats were treated with VPA (400 mg/kg S.C. diluted with normal saline at E12. To analyze the cell death, we performed PI staining and PARP and caspase-3 cleavage assay. Expression level of proteins was investigated by Western blot and immunocytochemical assays. The level of mRNA expression was investigated by RT-PCR. Interaction of Bcl-XL gene promoter and NF-κB p65 was investigated by ChIP assay. Results In this study, FACS analysis, PI staining and PARP and caspase-3 cleavage assay showed that VPA protects cultured NPCs from cell death after growth factor withdrawal both in basal and staurosporine- or hydrogen peroxide-stimulated conditions. The protective effect of prenatally injected VPA was also observed in E16 embryonic brain. Treatment of VPA decreased the level of IκBα and increased the nuclear translocation of NF-κB, which subsequently enhanced expression of anti-apoptotic protein Bcl-XL. Conclusion To the best of our knowledge, this is the first report to indicate the reduced death of NPCs by VPA at developmentally

  11. Possibilities and prospects of investigation of irradiated structural and fuel materials using scanning electron microscope PHILLIPS XL 30 ESEM-TMP installed in the hot cell

    International Nuclear Information System (INIS)

    Golovanov, V. N.; Novoselov, A.E.; Kuzmin, S.V.; Yakovlev, V. V.

    2005-01-01

    Scanning electron microscope Philips XL 30 ESEM - TMP with X-ray microanalysis system INCA has been installed at SSC RF RIAR. The microscope is placed in the hot cell. Monitoring and control system is installed in the operator's room. Irradiated specimens are supplied to the hot cell through the transport terminal and installed into the microscope by manipulators. Direct contact of the personnel with radioactive materials is impossible. In addition it is developed the system of remote placement of the irradiated specimens into the specimen chamber of microscope. The system includes a stage with three seats, holders for different types of specimens and equipment for their remote loading in the holders. (Author)

  12. Full Scale Bioreactor Landfill for Carbon Sequestration and Greenhouse Emission Control

    Energy Technology Data Exchange (ETDEWEB)

    Ramin Yazdani; Jeff Kieffer; Kathy Sananikone; Don Augenstein

    2005-03-30

    The Yolo County Department of Planning and Public Works constructed a full-scale bioreactor landfill as a part of the Environmental Protection Agency's (EPA) Project XL program to develop innovative approaches for carbon sequestration and greenhouse emission control. The overall objective was to manage landfill solid waste for rapid waste decomposition and maximum landfill gas generation and capture for carbon sequestration and greenhouse emission control. Waste decomposition is accelerated by improving conditions for either the aerobic or anaerobic biological processes and involves circulating controlled quantities of liquid (leachate, groundwater, gray water, etc.), and, in the aerobic process, large volumes of air. The first phase of the project entailed the construction of a 12-acre module that contained a 6-acre anaerobic cell, a 3.5-acre anaerobic cell, and a 2.5-acre aerobic cell at the Yolo County Central Landfill near Davis, California. The cells were highly instrumented to monitor bioreactor performance. Liquid addition commenced in the 3.5-acre anaerobic cell and the 6-acre anaerobic cell. Construction of the 2.5-acre aerobic cell and biofilter has been completed. The current project status and preliminary monitoring results are summarized in this report.

  13. Preliminary design and thermal analysis of device for finish cooling Jaffa biscuits in a.d. 'Jaffa'- Crvenka

    Directory of Open Access Journals (Sweden)

    Salemović Duško R.

    2015-01-01

    Full Text Available In this paper preliminary design of device for finish cooling chocolate topping of biscuits in A.D. 'Jaffa'- Crvenka was done. The proposed preliminary design followed by the required technological process of finish cooling biscuits and required parameters of process which was supposed to get and which represented part of project task. Thermal analysis was made and obtained percentage error between surface contact of the air and chocolate topping, obtained from heat balance and geometrical over proposed preliminary design, wasn't more than 0.67%. This is a preliminary design completely justified because using required length of belt conveyor receive required temperature of chocolate topping at the end of the cooling process.

  14. Direct visualization of in vitro drug mobilization from Lescol XL tablets using two-dimensional (19)F and (1)H magnetic resonance imaging.

    Science.gov (United States)

    Chen, Chen; Gladden, Lynn F; Mantle, Michael D

    2014-02-03

    This article reports the application of in vitro multinuclear ((19)F and (1)H) two-dimensional magnetic resonance imaging (MRI) to study both dissolution media ingress and drug egress from a commercial Lescol XL extended release tablet in a United States Pharmacopeia Type IV (USP-IV) dissolution cell under pharmacopoeial conditions. Noninvasive spatial maps of tablet swelling and dissolution, as well as the mobilization and distribution of the drug are quantified and visualized. Two-dimensional active pharmaceutical ingredient (API) mobilization and distribution maps were obtained via (19)F MRI. (19)F API maps were coregistered with (1)H T2-relaxation time maps enabling the simultaneous visualization of drug distribution and gel layer dynamics within the swollen tablet. The behavior of the MRI data is also discussed in terms of its relationship to the UV drug release behavior.

  15. High School Geography Project. Legacy for the Seventies. An Analysis of the High School Geography Project in Relation to New Developments in Geographic Education Worldwide.

    Science.gov (United States)

    Gunn, Angus M., Ed.

    Nine articles by geographers and educators analyze the High School Geography Project (HSGP). A project overview by Angus Gunn presents essential ideas and content of six units and several preliminary reactions. The question of "HSGP exportability" to France and Germany is examined in articles by Maurice Saint-Yves and Robert Geipel…

  16. Solar electricity power station building. A preliminary project investigation for “PIRIN TEX LTD.” – Gotze Delchgev using

    International Nuclear Information System (INIS)

    Kolev, Boyko; Todorieva, Vanja

    2009-01-01

    The total solar energy absorbed by Earth's atmosphere, oceans and land masses is approximately 3,850,000 exa joules (EJ=1018 J) per year. In 2005, this was more energy in one hour than the world used in one year. Photosynthesis captures approximately 3,000 EJ per year in biomass. The amount of solar energy reaching the surface of the planet is so vast that in one year it is about twice as much as will ever be obtained from all of the Earth's non-renewable resources of coal, oil, natural gas, and mined uranium combined. Natural gas crisis such as this from January 2009 in Bulgaria turn into the best investments the development of technology for renewable energy sources using especially solar energy using for electricity production and water heating. The aims of this article are: To develop a preliminary project for solar electricity power station build-ing; To estimate the profits of solar energy used for electricity production and water heating. Keywords: renewable energy sources, solar energy accumulation, solar electricity power station, natural gas crisis

  17. AVLIS Production Plant Preliminary Quality Assurance Plan and Assessment

    International Nuclear Information System (INIS)

    1984-01-01

    This preliminary Quality Assurance Plan and Assessment establishes the Quality Assurance requirements for the AVLIS Production Plant Project. The Quality Assurance Plan defines the management approach, organization, interfaces, and controls that will be used in order to provide adequate confidence that the AVLIS Production Plant design, procurement, construction, fabrication, installation, start-up, and operation are accomplished within established goals and objectives. The Quality Assurance Program defined in this document includes a system for assessing those elements of the project whose failure would have a significant impact on safety, environment, schedule, cost, or overall plant objectives. As elements of the project are assessed, classifications are provided to establish and assure that special actions are defined which will eliminate or reduce the probability of occurrence or control the consequences of failure. 8 figures, 18 tables

  18. Preliminary Design Requirements Document for Project W-314

    Energy Technology Data Exchange (ETDEWEB)

    MCGREW, D.L.

    2000-04-27

    This document sets forth functional requirements, performance requirements, and design constraints for the tank farm systems elements identified in Section 3.1 of this document. These requirements shall be used to develop the Design Requirements Baseline for those system elements. System Overview--The tank farm system at Hanford Site currently consists of 149 single shell tanks and 28 double shell tanks with associated facilities and equipment, located in 18 separate groupings. Each grouping is known as a tank farm. They are located in the areas designated as 200 West and 200 East. Table 1-1 shows the number of tanks in each farm. The farms are connected together through a transfer system consisting of piping, diversion boxes, Double Contained Receiver Tanks (DCRT) and other miscellaneous facilities and elements. The tank farm system also connects to a series of processing plants which generate radioactive and hazardous wastes. The primary functions of the tank farm system are to store, transfer, concentrate, and characterize radioactive and hazardous waste generated at Hanford, until the waste can be safely retrieved, processed and dispositioned. The systems provided by Project W-314 support the store and transfer waste functions. The system elements to be upgraded by Project W-314 are identified in Section 3.1.

  19. Preliminary Design Requirements Document for Project W-314

    International Nuclear Information System (INIS)

    MCGREW, D.L.

    2000-01-01

    This document sets forth functional requirements, performance requirements, and design constraints for the tank farm systems elements identified in Section 3.1 of this document. These requirements shall be used to develop the Design Requirements Baseline for those system elements. System Overview--The tank farm system at Hanford Site currently consists of 149 single shell tanks and 28 double shell tanks with associated facilities and equipment, located in 18 separate groupings. Each grouping is known as a tank farm. They are located in the areas designated as 200 West and 200 East. Table 1-1 shows the number of tanks in each farm. The farms are connected together through a transfer system consisting of piping, diversion boxes, Double Contained Receiver Tanks (DCRT) and other miscellaneous facilities and elements. The tank farm system also connects to a series of processing plants which generate radioactive and hazardous wastes. The primary functions of the tank farm system are to store, transfer, concentrate, and characterize radioactive and hazardous waste generated at Hanford, until the waste can be safely retrieved, processed and dispositioned. The systems provided by Project W-314 support the store and transfer waste functions. The system elements to be upgraded by Project W-314 are identified in Section 3.1

  20. 75 FR 66083 - Iron Mask Hydro, LLC; Notice of Preliminary Permit Application Accepted for Filing and Soliciting...

    Science.gov (United States)

    2010-10-27

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Project No. 13723-000] Iron Mask Hydro..., Iron Mask Hydro, LLC filed an application for a preliminary permit, pursuant to section 4(f) of the Federal Power Act (FPA), proposing to study the feasibility of the Iron Mask Pumped Storage Project to be...

  1. Effect of fabrication pressure on the fatigue performance of Cemex XL acrylic bone cement.

    Science.gov (United States)

    Lewis, Gladius; Janna, S I

    2004-01-01

    During a cemented arthroplasty, the prepared polymerizing dough of acrylic bone cement is subjected to pressurization in a number of ways; first, during delivery into the freshly prepared bone bed, second, during packing in that bed (either digitally or with the aid of a mechanical device), and, third, during the insertion of the prosthesis. Only a few studies have reported on the influence of the level of pressurization experienced during these events (which, depending on the cementing technique used, has been put at between 8 and 273 kPa) on various properties of the cement. That was the focus of the present study, in which the fully reversed tension-compression (+/-15 MPa; 5 Hz) fatigue lives (expressed as number of cycles to fracture, N(f)) of rectangular cross-sectioned "dog-bone" specimens (Type V, per ASTM D 638) fabricated from Cemex XL cement, at pressure applied continuously to the cement dough during curing in the specimen mold, p=75,150, and 300 kPa, were determined. The N(f) results were analyzed using the linearized transformation of the three-parameter Weibull relationship to obtain estimates of the Weibull mean, N(WM), which was taken to be the index of fatigue performance of the specimen set. Over the range of p studied, N(WM) increased as p increased (for example, from 329,118 cycles when p was 75 kPa to 388,496 cycles when p was 300 kPa); however, the increase was not significant over any pair of p increment steps (Mann-Whitney U-test; alpha<0.05).

  2. Innovative approach for restoring coastal wetlands using treated drill cuttings

    International Nuclear Information System (INIS)

    Veil, J. A.; Hocking, E. K.

    1999-01-01

    The leading environmental problem facing coastal Louisiana regions is the loss of wetlands. Oil and gas exploration and production activities have contributed to wetland damage through erosion at numerous sites where canals have been cut through the marsh to access drilling sites. An independent oil and gas producer, working with Southeastern Louisiana University and two oil field service companies, developed a process to stabilize drill cuttings so that they could be used as a substrate to grow wetlands vegetation. The U.S. Department of Energy (DOE) funded a project under which the process would be validated through laboratory studies and field demonstrations. The laboratory studies demonstrated that treated drill cuttings support the growth of wetlands vegetation. However, neither the Army Corps of Engineers (COE) nor the U.S. Environmental Protection Agency (EPA) would grant regulatory approval for afield trial of the process. Argonne National Laboratory was asked to join the project team to try to find alternative mechanisms for gaining regulatory approval. Argonne worked with EPA's Office of Reinvention and learned that EPA's Project XL would be the only regulatory program under which the proposed field trial could be done. One of the main criteria for an acceptable Project XL proposal is to have a formal project sponsor assume the responsibility and liability for the project. Because the proposed project involved access to private land areas, the team felt that an oil and gas company with coastal Louisiana land holdings would need to serve as sponsor. Despite extensive communication with oil and gas companies and industry associations, the project team was unable to find any organization willing to serve as sponsor. In September 1999, the Project XL proposal was withdrawn and the project was canceled

  3. ICT and UD: Preliminary Study for Recommendations to Design Accessible University Courses.

    Science.gov (United States)

    Pagliara, Silvio Marcello; Sánchez Utgé, Marta; De Anna, Lucia

    2017-01-01

    Starting from the Universal Design in the educational context principles, the experiences gained during the FIRB project "Net@ccessibility" and the high-education courses for teachers' specialization on special education, this research will focus on preliminary studies in order to define the recommendations for designing accessible university courses.

  4. Examining engineering costs for development of highway projects.

    Science.gov (United States)

    2012-12-01

    The Texas Department of Transportation (TxDOT) commissioned a research team at Texas State University-San Marcos Department of Accounting to analyze the cost of projects by determining the cost of a preliminary engineering hour necessary to develop h...

  5. Gene Expression of Lytic Endopeptidases AlpA and AlpB from Lysobacter sp. XL1 in Pseudomonads.

    Science.gov (United States)

    Tsfasman, Irina M; Lapteva, Yulia S; Krasovskaya, Ludmila A; Kudryakova, Irina V; Vasilyeva, Natalia V; Granovsky, Igor E; Stepnaya, Olga A

    2015-01-01

    Development of an efficient expression system for (especially secreted) bacterial lytic enzymes is a complicated task due to the specificity of their action. The substrate for such enzymes is peptidoglycan, the main structural component of bacterial cell walls. For this reason, expression of recombinant lytic proteins is often accompanied with lysis of the producing bacterium. This paper presents data on the construction of an inducible system for expression of the lytic peptidases AlpA and AlpB from Lysobacter sp. XL1 in Pseudomonas fluorescens Q2-87, which provides for the successful secretion of these proteins into the culture liquid. In this system, the endopeptidase gene under control of the T7lac promoter was integrated into the bacterial chromosome, as well as the Escherichia coli lactose operon repressor protein gene. The T7 pol gene under lac promoter control, which encodes the phage T7 RNA polymerase, is maintained in Pseudomonas cells on the plasmids. Media and cultivation conditions for the recombinant strains were selected to enable the production of AlpA and AlpB by a simple purification protocol. Production of recombinant lytic enzymes should contribute to the development of new-generation antimicrobial drugs whose application will not be accompanied by selection of resistant microorganisms. © 2015 S. Karger AG, Basel.

  6. Preliminary Examination of the Supply and Demand Balance for Renewable Electricity

    Energy Technology Data Exchange (ETDEWEB)

    Swezey, B.; Aabakken, J.; Bird, L.

    2007-10-01

    In recent years, the demand for renewable electricity has accelerated as a consequence of state and federal policies and the growth of voluntary green power purchase markets, along with the generally improving economics of renewable energy development. This paper reports on a preliminary examination of the supply and demand balance for renewable electricity in the United States, with a focus on renewable energy projects that meet the generally accepted definition of "new" for voluntary market purposes, i.e., projects installed on or after January 1, 1997. After estimating current supply and demand, this paper presents projections of the supply and demand balance out to 2010 and describe a number of key market uncertainties.

  7. Cost Finding Principles and Procedures. Preliminary Field Review Edition. Technical Report 26.

    Science.gov (United States)

    Ziemer, Gordon; And Others

    This report is part of the Larger Cost Finding Principles Project designed to develop a uniform set of standards, definitions, and alternative procedures that will use accounting and statistical data to find the full cost of resources utilized in the process of producing institutional outputs. This technical report describes preliminary procedures…

  8. Cost analysis of small hydroelectric power plants components and preliminary estimation of global cost

    International Nuclear Information System (INIS)

    Basta, C.; Olive, W.J.; Antunes, J.S.

    1990-01-01

    An analysis of cost for each components of Small Hydroelectric Power Plant, taking into account the real costs of these projects is shown. It also presents a global equation which allows a preliminary estimation of cost for each construction. (author)

  9. Sniffer project development

    CERN Document Server

    Grau, S; CERN. Geneva. ST Division

    2002-01-01

    To ensure the safety of the personnel, and prevent major damage to the equipment in the LHC experiments, a combined fire and gas detection system is being developed in conjunction with the industry. This system named SNIFFER, shall detect fire, flammable gas leaks and oxygen deficiency. In addition it shall interface with the Experiments' Control System and the CERN Safety Alarm Monitoring system. The SNIFFER project is currently at the end of the prototyping phase, and the technical specification is being written for the outsourcing of the system. The purpose of this document is to describe the main functions, constraints and interfaces of the system, to present the status report and planning of the project, and to explain the preliminary conclusions of the prototyping phase.

  10. NCSS Peace Studies Project: An Interim Report.

    Science.gov (United States)

    Ferber, Michael

    This preliminary report of a National Council for the Social Studies (NCSS) project briefly assesses teaching materials related to peace and nuclear warfare. Covering elementary, secondary, and higher education, the materials discussed present a variety of activities, decision-making approaches, and analytical assessments of policies of many…

  11. Characterization of the Human Proteomic Response to Hydrocodone: A Preliminary Study

    Science.gov (United States)

    2014-05-01

    Bjork, S.J. Grant , Does traumatic brain injury increase risk for substance abuse?, J Neurotrauma (2009). [13] D.P. Graham, A.L. Cardon , An update on...Preliminary Study” 5a. CONTRACT NUMBER 5b. GRANT NUMBER W81XWH-11-2-0126 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) Lt Col Vikhyat Bebarta, MD 5d. PROJECT

  12. Student design projects in applied acoustics.

    Science.gov (United States)

    Bös, Joachim; Moritz, Karsten; Skowronek, Adam; Thyes, Christian; Tschesche, Johannes; Hanselka, Holger

    2012-03-01

    This paper describes a series of student projects which are intended to complement theoretical education in acoustics and engineering noise control with practical experience. The projects are also intended to enhance the students' ability to work in a team, to manage a project, and to present their results. The projects are carried out in close cooperation with industrial partners so that the students can get a taste of the professional life of noise control engineers. The organization of such a project, its execution, and some of the results from the most recent student project are presented as a demonstrative example. This latest project involved the creation of noise maps of a production hall, the acoustic analysis of a packaging machine, and the acoustic analysis of a spiral vibratory conveyor. Upon completion of the analysis, students then designed, applied, and verified some simple preliminary noise reduction measures to demonstrate the potential of these techniques. © 2012 Acoustical Society of America

  13. Mid-Columbia coho reintroduction feasibility project. Preliminary environmental assessment

    International Nuclear Information System (INIS)

    1999-01-01

    Before the Bonneville Power Administration (BPA) decides whether to fund a program to reintroduce coho salmon to mid-Columbia River basin tributaries, research is needed to determine the ecological risks and biological feasibility of such an effort. Since the early 1900s, the native stock of coho has been decimated in the tributaries of the middle reach of the Columbia River. The four Columbia River Treaty Tribes identified coho reintroduction in the mid-Columbia as a priority in the Tribal Restoration Plan. It is a comprehensive plan put forward by the Tribes to restore the Columbia River fisheries. In 1996, the Northwest Power Planning Council (NPPC) recommended the tribal mid-Columbia reintroduction project for funding by BPA. It was identified as one of fifteen high-priority supplementation projects for the Columbia River basin, and was incorporated into the NPPC's Fish and Wildlife Program. The release of coho from lower Columbia hatcheries into mid-Columbia tributaries is also recognized in the Columbia River Fish Management Plan

  14. Baseline comparison report for Project W-058, Replacement of the cross-site transfer system. Revision 1

    International Nuclear Information System (INIS)

    Mendoza, D.P.

    1995-01-01

    This BCR compares the Project W-058 Functional Design Criteria with the Project W-058 Preliminary Design Requirements Document, and identifies the differences between the two documents in the mission definition, project requirements, system functions, and interfaces. Impacts these differences have on current project design are also discussed

  15. Critical path analysis in early stage of nuclear power project

    International Nuclear Information System (INIS)

    Xie Ahai

    2009-01-01

    The technical program and contract model as well as project management system and preliminary design defined in the early stage of nuclear power project are the key condition impact on the quality, schedule and cost of the nuclear power project. This paper, taking the CPR1000 coastal nuclear power station as an example, analyzes the critical path in the early stage of nuclear power project for five fields, i.e. licensing, design and procurement, site preparation, tender of construction contracts and construction preparation, and organization. (authors)

  16. Carbon stocks in Norwegian forested systems. Preliminary data

    Directory of Open Access Journals (Sweden)

    Oyen BH.

    2000-01-01

    Full Text Available Between 1990 and 2010 the projected emissions of greenhouse gases in Norway is assumed to increase 24%. As a signatory to the Kyoto Protocol, Norway is supposed to limit the greenhouse gas emissions in the period 2008–2012 to 1% above the 1990 level. Potentially, forestry activities may contribute as a means to achieve the set target of emission reductions. The initial Norwegian views and proposals for definitions and accounting framework for activities under Articles 3.3 and 3.4 of the Kyoto Protocol was reported to the UNFCCC August 1 2000 by the Norwegian Ministry of Environment. There was also an annex to the submission with preliminary data and information on Articles 3.3 and 3.4 of the Kyoto Protocol. This paper is based on this annex, and focuses mainly on data for forests and other woodlands. Preliminary data indicate that approximately 85% of the carbon (C pool of forested systems is found in the soil. The major part of the annual C sequestration takes place in living biomass and soil, while sequestration in wood products and landfills etc. has been found to be of minor importance. It must be noted that the reported data are preliminary and contain large uncertainties.

  17. Preliminary High-Throughput Metagenome Assembly

    Energy Technology Data Exchange (ETDEWEB)

    Dusheyko, Serge; Furman, Craig; Pangilinan, Jasmyn; Shapiro, Harris; Tu, Hank

    2007-03-26

    Metagenome data sets present a qualitatively different assembly problem than traditional single-organism whole-genome shotgun (WGS) assembly. The unique aspects of such projects include the presence of a potentially large number of distinct organisms and their representation in the data set at widely different fractions. In addition, multiple closely related strains could be present, which would be difficult to assemble separately. Failure to take these issues into account can result in poor assemblies that either jumble together different strains or which fail to yield useful results. The DOE Joint Genome Institute has sequenced a number of metagenomic projects and plans to considerably increase this number in the coming year. As a result, the JGI has a need for high-throughput tools and techniques for handling metagenome projects. We present the techniques developed to handle metagenome assemblies in a high-throughput environment. This includes a streamlined assembly wrapper, based on the JGI?s in-house WGS assembler, Jazz. It also includes the selection of sensible defaults targeted for metagenome data sets, as well as quality control automation for cleaning up the raw results. While analysis is ongoing, we will discuss preliminary assessments of the quality of the assembly results (http://fames.jgi-psf.org).

  18. Ecological economics - a special perspective? Preliminary reflections

    DEFF Research Database (Denmark)

    Røpke, Inge

    2002-01-01

    This paper reports on some preliminary reflections from a research project concerning ecological economics as a special perspective. As Clive Spash noted in a presentation at the ESEE conference in Cambridge, July 2001, ecological economics has reached the age of puberty, looks into the glass...... and searches its own identity. The identity seeking processes are visible in the large number of publications discussing the characteristics of ecological economics as well as the similarities to and differences from environmental economics. The present paper is a part of this stream. The paper is work...

  19. Preliminary AD-Horn Thermomechanical and Electrodynamic Simulations

    CERN Document Server

    AUTHOR|(CDS)2095747; Horvath, David; Calviani, Marco

    2016-01-01

    As part of the Antiproton Decelerator (AD) target area consolidation activities planned for LS2, it has been necessary to perform a comprehensive study of the thermo-structural behaviour of the AD magnetic horn during operation, in order to detail specific requirements for the upgrade projects and testing procedures. The present work illustrates the preliminary results of the finite element analysis carried out to evaluate the thermal and structural behaviour of the device, as well as the methodology used to model and solve the thermomechanical and electrodynamic simulations performed in the AD magnetic horn.

  20. Towards understanding household-level forest reliance in Cambodia - study sites, methods, and preliminary findings

    DEFF Research Database (Denmark)

    Ra, Koy; Pichdara, Lonn; Dararath, Yem

    There is growing international interest in the role of forests in poverty prevention and reduction. In consequence, this broad area of investigation has been subject to increased research; one major international research project is that facilitated by the Poverty Environment Network (PEN). This ......). This project covers a large number of sites in 26 countries throughout the tropics. The present report contains contextual details, methodological information and preliminary findings for the PEN sites in Cambodia....

  1. Phase 1 of the Hanford Environmental Dose Reconstruction Project

    International Nuclear Information System (INIS)

    1991-08-01

    The work described in this report was prompted by the public's concern about potential effect from the radioactive materials released from the Hanford Site. The Hanford Environmental Dose Reconstruction (HEDR) Project was established to estimate radiation dose the public might have received from the Hanford Site since 1944, when facilities began operating. Phase 1 of the HEDR Project is a ''pilot'' or ''demonstration'' phase. The objectives of this initial phase were to determine whether enough historical information could be found or reconstructed to be used for dose estimation and develop and test conceptual and computational models for calculating credible dose estimates. Preliminary estimates of radiation doses were produced in Phase 1 because they are needed to achieve these objectives. The reader is cautioned that the dose estimates provided in this and other Phase 1 HEDR reports are preliminary. As the HEDR Project continues, the dose estimates will change for at least three reasons: more complete input information for models will be developed; the models themselves will be refined; and the size and shape of the geographic study area will change. This is one of three draft reports that summarize the first phase of the four-phased HEDR Project. This, the Summary Report, is directed to readers who want a general understanding of the Phase 1 work and preliminary dose estimates. The two other reports -- the Air Pathway Report and the Columbia River Pathway Report -- are for readers who understand the radiation dose assessment process and want to see more technical detail. Detailed descriptions of the dose reconstruction process are available in more than 20 supporting reports listed in Appendix A. 32 refs., 46 figs

  2. Demonstration of Autonomous Rendezvous Technology (DART) Project Summary

    Science.gov (United States)

    Rumford, TImothy E.

    2003-01-01

    Since the 1960's, NASA has performed numerous rendezvous and docking missions. The common element of all US rendezvous and docking is that the spacecraft has always been piloted by astronauts. Only the Russian Space Program has developed and demonstrated an autonomous capability. The Demonstration of Autonomous Rendezvous Technology (DART) project currently funded under NASA's Space Launch Initiative (SLI) Cycle I, provides a key step in establishing an autonomous rendezvous capability for the United States. DART's objective is to demonstrate, in space, the hardware and software necessary for autonomous rendezvous. Orbital Sciences Corporation intends to integrate an Advanced Video Guidance Sensor and Autonomous Rendezvous and Proximity Operations algorithms into a Pegasus upper stage in order to demonstrate the capability to autonomously rendezvous with a target currently in orbit. The DART mission will occur in April 2004. The launch site will be Vandenburg AFB and the launch vehicle will be a Pegasus XL equipped with a Hydrazine Auxiliary Propulsion System 4th stage. All mission objectives will be completed within a 24 hour period. The paper provides a summary of mission objectives, mission overview and a discussion on the design features of the chase and target vehicles.

  3. ADS project in the Vinca Institute

    International Nuclear Information System (INIS)

    Pesic, M.; Neskovic, N.; Plecas, I.

    1999-01-01

    Among the six scientific programmes proposed for future research in the Vinca Institute, the nuclear one is connected to the nuclear reactors and waste management activities. One of the projects within the nuclear programme is associated to a proposal for designing a small modern subcritical research reactor driven by an accelerator beam. The idea of this Project is based on the facts that the construction of the Tesla accelerator installation is in the final phase and that a rich experience is gained in design, construction, operation and maintenance of both research reactors in the Institute in the last 40 years. Preliminary scope of the ADS project in the Vinca Institute, including some details and options, are given (author)

  4. Transport Infrastructure Surveillance and Monitoring by Electromagnetic Sensing: The ISTIMES Project

    Directory of Open Access Journals (Sweden)

    Marie Bost

    2010-11-01

    Full Text Available The ISTIMES project, funded by the European Commission in the frame of a joint Call “ICT and Security” of the Seventh Framework Programme, is presented and preliminary research results are discussed. The main objective of the ISTIMES project is to design, assess and promote an Information and Communication Technologies (ICT-based system, exploiting distributed and local sensors, for non-destructive electromagnetic monitoring of critical transport infrastructures. The integration of electromagnetic technologies with new ICT information and telecommunications systems enables remotely controlled monitoring and surveillance and real time data imaging of the critical transport infrastructures. The project exploits different non-invasive imaging technologies based on electromagnetic sensing (optic fiber sensors, Synthetic Aperture Radar satellite platform based, hyperspectral spectroscopy, Infrared thermography, Ground Penetrating Radar-, low-frequency geophysical techniques, Ground based systems for displacement monitoring. In this paper, we show the preliminary results arising from the GPR and infrared thermographic measurements carried out on the Musmeci bridge in Potenza, located in a highly seismic area of the Apennine chain (Southern Italy and representing one of the test beds of the project.

  5. Northern California CO2 Reduction Project

    Energy Technology Data Exchange (ETDEWEB)

    Hymes, Edward [C6 Resources LLC, Houston, TX (United States)

    2010-06-16

    forth in California's Climate Change law, presents a major opportunity for both the environment as well as the region. C6 Resources is conducting the Project in collaboration with federally-funded research centers, such as Lawrence Berkeley National Lab and Lawrence Livermore National Lab. C6 Resources and Shell have identified CCS as one of the critical pathways toward a worldwide goal of providing cleaner energy. C6 Resources, in conjunction with the West Coast Regional Carbon Sequestration Partnership (WESTCARB), has conducted an extensive and ongoing public outreach and CCS education program for local, regional and state-wide stakeholders. As part of a long term relationship, C6 Resources will continue to engage directly with community leaders and residents to ensure public input and transparency. This topical report summarizes the technical work from Phase 1 of the Project in the following areas; Surface Facility Preliminary Engineering: summarizes the preliminary engineering work performed for CO2 capture, CO2 compression and dehydration at the refinery, and surface facilities at the sequestration site; Pipeline Preliminary Engineering: summarizes the pipeline routing study and preliminary engineering design; Geologic Sequestration: summarizes the work to characterize, model and evaluate the sequestration site; and Monitoring, Verification and Accounting (MVA): summarizes the MVA plan to assure long-term containment of the sequestered CO2.

  6. 76 FR 52656 - Rhode Island Department of Environmental Management; Notice of Preliminary Permit Application...

    Science.gov (United States)

    2011-08-23

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Project No. 14211-000] Rhode Island Department of Environmental Management; Notice of Preliminary Permit Application Accepted for Filing and Soliciting Comments, Motions To Intervene, and Competing Applications On June 10, 2011, the Rhode Island Department of Environmental Management...

  7. FY 1980 Report on results of research and development project, commissioned by Sunshine Project. Researches on R and D of management procedures; 1980 nendo kenkyu kaihatsu kanri shuho no kenkyu seika hokokusho

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1981-03-01

    The strategic system planning procedures have been developed and applied for drafting R and D targets and subsequent medium-term plans, in order to help promote the Sunshine Project smoothly, based on the long-term prospects. This project compares the developed procedures with the current promotion systems and R and D management supporting procedures, to establish the strategic system planning procedures. These newly developed procedures are expected to accelerate the Sunshine Project, when applied in the standard manner. They are also partly applied to coal liquefaction techniques for (system demand analysis), the results of which are used to propose the ideal R and D targets of these techniques. The milestone planning procedures are preliminary applied to (establishing the project plans), to draw systematic long-, medium- and short-term plans. The preliminary application of these prediction/analysis and supporting procedures has verified effectiveness of the strategic system planning procedures. (NEDO)

  8. Preliminary prediction of inflow into the D-holes at the Stripa Mine

    International Nuclear Information System (INIS)

    Long, J.C.S.; Karasaki, K.; Davey, A.; Peterson, J.; Landsfeld, M.; Kemeny, J.; Martel, S.

    1990-02-01

    Lawrence Berkeley Laboratory (LBL) is contracted by the US Department of Energy to provide an auxiliary modeling effort for the Stripa Project. Within this effort, we are making calculations of inflow to the Simulated Drift Experiment (SDE), i.e. inflow to six parallel, closely spaced D-holes, using a preliminary set of data collected in five other holes, the N- and W-holes during Stages 1 and 2 of the Site Characterization and Validation (SCV) project. Our approach has been to focus on the fracture zones rather than the general set of ubiquitous fractures. Approximately 90% of all the water flowing in the rock is flowing in fracture zones which are neither uniformly conductive nor are they infinitely extensive. Our approach has been to adopt the fracture zone locations as they have been identified with geophysics. We use geologic sense and the original geophysical data to add one zone where significant water inflow has been observed that can not be explained with the other geophysical zones. This report covers LBL's preliminary prediction of flow into the D-holes. Care should be taken in interpreting the results given in this report. As explained below, the approach that LBL has designed for developing a fracture hydrology model requires cross-hole hydrologic data. Cross-hole tests are planned for Stage 3 but were unavailable in Stage 1. As such, we have inferred from available data what a cross-hole test might show and used this synthetic data to make a preliminary calculation of the inflow into the D-holes. Then using all the Stage 3 data we will calculate flow into the Validation Drift itself. The report mainly demonstrates the use of our methodology and the simulated results should be considered preliminary

  9. 75 FR 8320 - Coastal Hydropower LLC; Notice of Preliminary Permit Application Accepted for Filing and...

    Science.gov (United States)

    2010-02-24

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Project No. 13621-000] Coastal Hydropower LLC; Notice of Preliminary Permit Application Accepted for Filing and Soliciting Comments, Motions To Intervene, and Competing Applications February 18, 2010. On November 5, 2009, Coastal Hydropower...

  10. 76 FR 1613 - Mahoning Hydropower, LLC; Notice of Preliminary Permit Application Accepted for Filing and...

    Science.gov (United States)

    2011-01-11

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Project No. 13877-000] Mahoning Hydropower, LLC; Notice of Preliminary Permit Application Accepted for Filing and Soliciting Comments, Motions To Intervene, and Competing Applications January 4, 2011. On November 4, 2010, Mahoning Hydro, LLC...

  11. Traditional Games and Children of Today. Belgrade-OMEP Traditional Games Project.

    Science.gov (United States)

    Ivic, Ivan, Ed.; Marjanovic, Aleksandra, Ed.

    Collected in this volume are preliminary materials related to the Belgrade-OMEP Project whose purpose is to make a record of those traditional children's games which are a part of the folk culture of various countries. The purpose of this publication is two-fold: (1) to serve as a handbook for the present collaborators on the Project in their…

  12. Marine Hydrokinetic Projects for US Waters as of January 2016

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Pending or issued preliminary permits or issued licenses for marine hydrokinetic projects that produce energy from waves or directly from the flow of water in ocean...

  13. The Hel Peninsula – Smart Grid Pilot Project

    Directory of Open Access Journals (Sweden)

    Sławomir Noske

    2014-12-01

    Full Text Available The paper presents the scope and results of engineering, and the scope of Smart Grid deployment in the Hel Peninsula. The following functionalities will be described: Fault Detection, Isolation & Recovery – FDIR function, Integrated Volt/Var Control (IVVC function, advanced supervision of LV grid, including distributed energy resources. The paper contains implementation results and research findings, as well as preliminary cost-benefit analysis of the project. Moreover, since Smart Metering and Smart Grid projects are being deployed in the same region – the Hel Peninisula – the benefit achieved by merging the two projects will be explained.

  14. Collective effects and impedance issues for the SOLEIL project

    Energy Technology Data Exchange (ETDEWEB)

    Flynn, G [Paris-11 Univ., 91 - Orsay (France). Lab. pour l` Utilisation du Rayonnement Electromagnetique (LURE)

    1996-08-01

    Various issues related to collective effects in the SOLEIL project are addressed. Particular attention is paid to the effects of longitudinal oscillations on undulator brilliance. Preliminary estimates of turbulent bunch lengthening and of the transverse mode coupling threshold are presented. (author)

  15. Preliminary studies of consolidation of wall paintings: synthesis and characterisation of nanolime

    Directory of Open Access Journals (Sweden)

    Penka I. Girginova

    2016-01-01

    Full Text Available In this publication, we report the synthesis and characterization of calcium and magnesium hydroxides nanoparticles for consolidation of mural paintings. Some preliminary results are discussed. This research is the initial part of our ongoing project which aims to develop new synthetic strategies towards novel and innovative materials for preservation and restoration of old renders.

  16. Hemorrhagic Stroke in a Young Healthy Male Following Use of Pre-Workout Supplement Animal Rage XL.

    Science.gov (United States)

    Harris, Brandon F; Winn, Coty; Ableman, Thomas B

    2017-09-01

    So-called "pre-workout" supplements are substances marketed as natural dietary supplements with claims of helping athletes achieve more focused and intense workouts. The use of such products remains popular among American youth as a whole, but is especially high among active duty service members. Supplements are minimally regulated by the Food and Drug Administration (FDA), and unlike pharmaceuticals, supplements are often brought to market without any testing to show neither efficacy nor safety. Several case reports have documented serious adverse events and raise the question of whether supplement use was a causative factor. Reported events occurring after use of pre-workout supplements include, among others, ischemic stroke, hemorrhagic stroke, myocardial infarction, hepatitis, and death. Here, we present the case of a healthy 25-year-old active duty male who experienced a bilateral cerebellar hemorrhagic stroke occurring shortly after taking a supplement named Animal Rage XL. Hemorrhagic stroke occurring in a healthy 25-year-old male with no risk factors is exceedingly rare. This is the first known case of stroke temporally associated with this particular supplement, which is currently available for purchase at military exchanges. Additionally, several of the active ingredients in this supplement have been shown to cause hypertension, tachycardia, and vasospasm. All of these effects could increase the likelihood and severity of a hemorrhagic stroke. The investigated ingredients in this abstract include β-phenethylamine, creatine-monophosphate, and caffeine. Reprint & Copyright © 2017 Association of Military Surgeons of the U.S.

  17. Two Stage Fuzzy Methodology to Evaluate the Credit Risks of Investment Projects

    OpenAIRE

    O. Badagadze; G. Sirbiladze; I. Khutsishvili

    2014-01-01

    The work proposes a decision support methodology for the credit risk minimization in selection of investment projects. The methodology provides two stages of projects’ evaluation. Preliminary selection of projects with minor credit risks is made using the Expertons Method. The second stage makes ranking of chosen projects using the Possibilistic Discrimination Analysis Method. The latter is a new modification of a well-known Method of Fuzzy Discrimination Analysis.

  18. 75 FR 8321 - Coastal Hydropower LLC; Notice of Preliminary Permit Application Accepted for Filing and...

    Science.gov (United States)

    2010-02-24

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission Project No. 13619-000 Coastal Hydropower LLC; Notice of Preliminary Permit Application Accepted for Filing and Soliciting Comments, Motions to Intervene, and Competing Applications February 18, 2010. On November 5, 2009, Coastal Hydropower LLC filed...

  19. Project schedule and cost estimate report

    International Nuclear Information System (INIS)

    1988-03-01

    All cost tables represent obligation dollars, at both a constant FY 1987 level and an estimated escalation level, and are based on the FY 1989 DOE Congressional Budget submittal of December 1987. The cost tables display the total UMTRA Project estimated costs, which include both Federal and state funding. The Total Estimated Cost (TEC) for the UMTRA Project is approximately $992.5 million (in 1987 escalated dollars). Project schedules have been developed that provide for Project completion by September 1994, subject to Congressional approval extending DOE's authorization under Public Law 95-604. The report contains site-specific demographic data, conceptual design assumptions, preliminary cost estimates, and site schedules. A general project overview is also presented, which includes a discussion of the basis for the schedule and cost estimates, contingency assumptions, work breakdown structure, and potential project risks. The schedules and cost estimates will be revised as necessary to reflect appropriate decisions relating to relocation of certain tailings piles, or other special design considerations or circumstances (such as revised EPA groundwater standards), and changes in the Project mission. 27 figs', 97 tabs

  20. Radioactive materials in construction projects

    International Nuclear Information System (INIS)

    Herrmann, Ralf; Ohlendorf, Frank; Kaltz, Andrea Christine

    2014-01-01

    Till 1990 residues often of the former uranium mining were partly used as building material for road construction, terrain compensation and house construction in Saxony. These recommendations for action are addressed to applicants, planners and building constructors in the engineering and construction sector. It provides information for planning, preliminary investigations, applications, construction supervision related to radiation protection measures and documentation of construction projects where radioactive materials are expected.

  1. Novel and recurrent NDP gene mutations in familial cases of Norrie disease and X-linked exudative vitreoretinopathy.

    Science.gov (United States)

    Pelcastre, Erika L; Villanueva-Mendoza, Cristina; Zenteno, Juan C

    2010-05-01

    To present the results of molecular analysis of the NDP gene in Mexican families with Norrie disease (ND) and X-linked familial exudative vitreoretinopathy (XL-FEVR). Two unrelated families with ND and two with XL-FEVR were studied. Clinical diagnosis was suspected on the basis of a complete ophthalmologic examination. Molecular methods included DNA isolation from peripheral blood leucocytes, polymerase chain reaction amplification and direct nucleotide sequencing analysis of the complete coding region and exon-intron junctions of NDP. Haplotype analysis using NDP-linked microsatellites markers was performed in both ND families. A novel Norrin missense mutation, p.Arg41Thr, was identified in two apparently unrelated families with ND. Haplotype analysis demonstrated that affected males in these two families shared the same ND-linked haplotype, suggesting a common origin for this novel mutation. The previously reported p.Arg121Trp and p.Arg121Gln Norrin mutations were identified in the two families with XL-FEVR. Our results expand the mutational spectrum in ND. This is the first report of ND resulting from mutation at arginine position 41 of Norrin. Interestingly, mutations at the same residue but resulting in a different missense change were previously described in subjects with XL-FEVR (p.Arg41Lys) or persistent fetal vasculature syndrome (p.Arg41Ser), indicating that the novel p.Arg41Thr change causes a more severe retinal phenotype. Preliminary data suggest a founder effect for the ND p.Arg41Thr mutation in these two Mexican families.

  2. Coordination in contractual relations: Some preliminary findings from the Malaysian housing industry

    Directory of Open Access Journals (Sweden)

    Suraya Ismail

    2008-12-01

    Full Text Available The traditional general procurement route found in many housing projects in Malaysia is conceptualized as a governance structure following the transaction cost economics (TCE approach. This approach has been used to examine governance structures in different economic sectors in several countries but evidence of its use in the context of developing countries is limited. This lack of evidence has prompted the authors to conduct a preliminary study to ascertain whether a TCE approach can explain construction governance structures in developing countries. This research does not discuss the trade-off that governs the choice of hybrids, market or hierarchies for organizing transactions. Rather, it takes advantage of existing research to substantiate the specific properties of hybrid organizations as governance structures. The main focus is coordination. Coordination is specified at two levels. At Level 1 is the coordination of specialization (i.e. the formation of the project team members and at Level 2 is the coordination mode of the contracting parties (client and contractor and the agents involved (the lead designer and project manage r. A case survey method was adopted. Preliminary findings seem to suggest that clients have used hierarchical themes in the contracts and high powered incentives to coordinate with in the contracting parties. The research findings suggest that all participants involved in the sample studied used governance structures symptomatic of a hybrid organization.

  3. Report of preliminary investigations on the next-generation large-scale synchrotron radiation facility projects

    International Nuclear Information System (INIS)

    1990-01-01

    The Special Committee for Future Project of the Japanese Society for Synchrotron Radiation Research investigated the construction-projects of the large-scaled synchrotron radiation facilities which are presently in progress in Japan. As a result, the following both projects are considered the very valuable research-project which will carry the development of Japan's next-generation synchrotron radiation science: 1. the 8 GeV synchrotron radiation facilities (SPring-8) projected to be constructed by Japan Atomic Energy Research Institute and the Institute of Physical and Chemical Research under the sponsorship of Science Technology Agency at Harima Science Park City, Hyogo Pref., Japan. 2. The project to utilize the Tristan Main Ring (MR) of the National Laboratory for High Energy Physics as the radiation source. Both projects are unique in research theme and technological approach, and complemental each other. Therefore it has been concluded that both projects should be aided and ratified by the Society. (M.T.)

  4. QUEST2: Project plan for preliminary analysis/system architecture phase (PA/SA)

    International Nuclear Information System (INIS)

    Braaten, F.D.

    1995-01-01

    This Project Management Plan combines the project management deliverables from the P+ methodology that are applicable to this part of the QUEST2 work. This consolidation reflects discussions with WHC QA regarding an appropriate method for ensuring that P+ deliverables fulfill the intent of WHC-CM-3-10 and QR-19

  5. Preliminary performance assessment for the Waste Isolation Pilot Plant, December 1992. Volume 3, Model parameters: Sandia WIPP Project

    Energy Technology Data Exchange (ETDEWEB)

    1992-12-29

    This volume documents model parameters chosen as of July 1992 that were used by the Performance Assessment Department of Sandia National Laboratories in its 1992 preliminary performance assessment of the Waste Isolation Pilot Plant (WIPP). Ranges and distributions for about 300 modeling parameters in the current secondary data base are presented in tables for the geologic and engineered barriers, global materials (e.g., fluid properties), and agents that act upon the WIPP disposal system such as climate variability and human-intrusion boreholes. The 49 parameters sampled in the 1992 Preliminary Performance Assessment are given special emphasis with tables and graphics that provide insight and sources of data for each parameter.

  6. Lessons learned from decommissioning projects at Los Alamos National Laboratory

    International Nuclear Information System (INIS)

    Salazar, M.

    1995-01-01

    This paper describes lessons learned over the last 20 years from 12 decommissioning projects at Los Alamos National Laboratory. These lessons relate both to overall program management and to management of specific projects during the planning and operations phases. The issues include waste management; the National Environmental Policy Act (NEPA); the Resource Conservation and Recovery Act (RCRA); the Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA); contracting; public involvement; client/customer interface; and funding. Key elements of our approach are to be proactive; follow the observation method; perform field activities concurrently; develop strategies to keep reportable incidents from delaying work; seek and use programs, methods, etc., in existence to shorten learning curves; network to help develop solutions; and avoid overstudying and overcharacterizing. This approach results in preliminary plans that require very little revision before implementation, reasonable costs and schedules, early acquisition of permits and NEPA documents, preliminary characterization reports, and contracting documents. Our track record is good -- the last four projects (uranium and plutonium-processing facility and three research reactors) have been on budget and on schedule

  7. F-16XL Hybrid Reynolds-Averaged Navier-Stokes/Large Eddy Simulation on Unstructured Grids

    Science.gov (United States)

    Park, Michael A.; Abdol-Hamid, Khaled S.; Elmiligui, Alaa

    2015-01-01

    This study continues the Cranked Arrow Wing Aerodynamics Program, International (CAWAPI) investigation with the FUN3D and USM3D flow solvers. CAWAPI was established to study the F-16XL, because it provides a unique opportunity to fuse fight test, wind tunnel test, and simulation to understand the aerodynamic features of swept wings. The high-lift performance of the cranked-arrow wing planform is critical for recent and past supersonic transport design concepts. Simulations of the low speed high angle of attack Flight Condition 25 are compared: Detached Eddy Simulation (DES), Modi ed Delayed Detached Eddy Simulation (MDDES), and the Spalart-Allmaras (SA) RANS model. Iso- surfaces of Q criterion show the development of coherent primary and secondary vortices on the upper surface of the wing that spiral, burst, and commingle. SA produces higher pressure peaks nearer to the leading-edge of the wing than flight test measurements. Mean DES and MDDES pressures better predict the flight test measurements, especially on the outer wing section. Vorticies and vortex-vortex interaction impact unsteady surface pressures. USM3D showed many sharp tones in volume points spectra near the wing apex with low broadband noise and FUN3D showed more broadband noise with weaker tones. Spectra of the volume points near the outer wing leading-edge was primarily broadband for both codes. Without unsteady flight measurements, the flight pressure environment can not be used to validate the simulations containing tonal or broadband spectra. Mean forces and moment are very similar between FUN3D models and between USM3D models. Spectra of the unsteady forces and moment are broadband with a few sharp peaks for USM3D.

  8. 77 FR 58375 - Inglis Hydropower, LLC; Notice of Preliminary Permit Application Accepted for Filing and...

    Science.gov (United States)

    2012-09-20

    ... Hydropower, LLC; Notice of Preliminary Permit Application Accepted for Filing and Soliciting Comments, Motions To Intervene, and Competing Applications On May 18, 2012, Inglis Hydropower, LLC filed an... study the feasibility of a hydropower project located at the Inglis Bypass Channel, located on the...

  9. Integration of models for the Hanford Environmental Dose Reconstruction Project

    International Nuclear Information System (INIS)

    Napier, B.A.

    1991-01-01

    The objective of the Hanford Environmental Dose Reconstruction Project is to estimate the radiation dose that individuals could have received as a result of emissions from nuclear operations at Hanford since 1944. The objective of phase 1 of the project was to demonstrate through calculations that adequate models and support data exist or could be developed to allow realistic estimations of doses to individuals from releases of radionuclides to the environment that occurred as long as 45 years ago. Much of the data used in phase 1 was preliminary; therefore, the doses calculated must be considered preliminary approximations. This paper describes the integration of various models that was implemented for initial computer calculations. Models were required for estimating the quantity of radioactive material released, for evaluating its transport through the environment, for estimating human exposure, and for evaluating resultant doses

  10. Q-Sync Motors in Commercial Refrigeration. Preliminary Test Results and Projected Benefits

    Energy Technology Data Exchange (ETDEWEB)

    Fricke, Brian A. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Becker, Bryan R. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)

    2015-09-01

    This report provides background information on various fractional-horsepower electric motor technologies, summarizes initial data from a DOE-sponsored Q-Sync motor demonstration project, and extrapolates that data to project the potential economic and environmental benefits resulting from upgrading the current installed base of 9–12 W evaporator fan motors to Q-Sync motors.

  11. Frictional sliding in layered rock model: Preliminary experiments. Yucca Mountain Site Characterization Project

    International Nuclear Information System (INIS)

    Perry, K.E. Jr.; Buescher, B.J.; Anderson, D.; Epstein, J.S.

    1995-09-01

    An important aspect of determining the suitability of Yucca Mountain as a possible nuclear waste repository requires understanding the mechanical behavior of jointed rock-masses. To this end we have studied the frictional sliding between simulated rock joints in the laboratory using the technique of phase shifting moire interferometry. The models were made from stacks of Lexan plates and contained a central hole to induce slip between the plates when the models were loaded in compression. These preliminary results confirm the feasibility of the approach and show a clear evolution of slip as function of load

  12. School Improvement Plans and Student Achievement: Preliminary Evidence from the Quality and Merit Project in Italy

    Science.gov (United States)

    Caputo, Andrea; Rastelli, Valentina

    2014-01-01

    This study provides preliminary evidence from an Italian in-service training program addressed to lower secondary school teachers which supports school improvement plans (SIPs). It aims at exploring the association between characteristics/contents of SIPs and student improvement in math achievement. Pre-post standardized tests and text analysis of…

  13. Preliminary design studies for the DESCARTES and CIDER codes

    International Nuclear Information System (INIS)

    Eslinger, P.W.; Miley, T.B.; Ouderkirk, S.J.; Nichols, W.E.

    1992-12-01

    The Hanford Environmental Dose Reconstruction (HEDR) project is developing several computer codes to model the release and transport of radionuclides into the environment. This preliminary design addresses two of these codes: Dynamic Estimates of Concentrations and Radionuclides in Terrestrial Environments (DESCARTES) and Calculation of Individual Doses from Environmental Radionuclides (CIDER). The DESCARTES code will be used to estimate the concentration of radionuclides in environmental pathways, given the output of the air transport code HATCHET. The CIDER code will use information provided by DESCARTES to estimate the dose received by an individual. This document reports on preliminary design work performed by the code development team to determine if the requirements could be met for Descartes and CIDER. The document contains three major sections: (i) a data flow diagram and discussion for DESCARTES, (ii) a data flow diagram and discussion for CIDER, and (iii) a series of brief statements regarding the design approach required to address each code requirement

  14. Preliminary geologic map of the Lathrop Wells volcanic center

    International Nuclear Information System (INIS)

    Crowe, B.; Harrington, C.; McFadden, L.; Perry, F.; Wells, S.; Turrin, B.; Champion, D.

    1988-12-01

    A preliminary geologic map has been compiled for the bedrock geology of the Lathrop Wells volcanic center. The map was completed through use of a combination of stereo photographic interpretation and field mapping on color aerial photographs. These photographs (scale 1:4000) were obtained from American Aerial Surveys, Inc. They were flown on August 18, 1987, at the request of the Yucca Mountain Project (then Nevada Nuclear Waste Storage Investigations). The photographs are the Lathrop Wells VC-Area 25 series, numbers 1--32. The original negatives for these photographs are on file with American Aerial Surveys, Inc. Copies of the negatives have been archived at the Los Alamos National Laboratory, Group N-5. The preliminary geologic map is a bedrock geologic map. It does not show alluvial deposits, eolian sands, or scoria fall deposits from the youngest eruptive events. The units will be compiled on separate maps when the geomorphic and soils studies are more advanced

  15. Effective e-learning for health professionals and students--barriers and their solutions. A systematic review of the literature--findings from the HeXL project.

    Science.gov (United States)

    Childs, Sue; Blenkinsopp, Elizabeth; Hall, Amanda; Walton, Graham

    2005-12-01

    In 2003/4 the Information Management Research Institute, Northumbria University, conducted a research project to identify the barriers to e-learning for health professionals and students. The project also established possible ways to overcome these barriers. The North of England Workforce Development Confederation funded the project. The project comprised a systematic review of the literature on barriers to and solutions/critical success factors for e-learning in the health field. Fifty-seven references were suitable for analysis. This review was supplemented by a questionnaire survey of learners and an interview study of learning providers to ensure that data identified from the literature were grounded in reality. The main barriers are: requirement for change; costs; poorly designed packages; inadequate technology; lack of skills; need for a component of face-to-face teaching; time intensive nature of e-learning; computer anxiety. A range of solutions can solve these barriers. The main solutions are: standardization; strategies; funding; integration of e-learning into the curriculum; blended teaching; user friendly packages; access to technology; skills training; support; employers paying e-learning costs; dedicated work time for e-learning. The authors argue that librarians can play an important role in e-learning: providing support and support materials; teaching information skills; managing and providing access to online information resources; producing their own e-learning packages; assisting in the development of other packages.

  16. High Luminosity LHC Project Description

    CERN Document Server

    Apollinari, Giorgio; Rossi, Lucio

    2014-01-01

    The High Luminosity LHC (HL-LHC) is a novel configuration of the Large Hadron Collider, aiming at increasing the luminosity by a factor five or more above the nominal LHC design, to allow increasing the integrated luminosity, in the high luminosity experiments ATLAS and CMS, from the 300 fb-1 of the LHC original design up to 3000 fb-1 or more. This paper contains a short description of the main machine parameters and of the main equipment that need to be developed and installed. The preliminary cost evaluation and the time plan are presented, too. Finally, the international collaboration that is supporting the project, the governance and the project structure are discussed, too.

  17. Preliminary mapping of surficial geology of Midway Valley Yucca Mountain Project, Nye County, Nevada

    International Nuclear Information System (INIS)

    Wesling, J.R.; Bullard, T.F.; Swan, F.H.; Perman, R.C.; Angell, M.M.; Gibson, J.D.

    1992-04-01

    The tectonics program for the proposed high-level nuclear waste repository at Yucca Mountain in southwestern Nevada must evaluate the potential for surface faulting beneath the prospective surface facilities. To help meet this goal, Quaternary surficial mapping studies and photolineament analyses were conducted to provide data for evaluating the location, recency, and style of faulting with Midway Valley at the eastern base of Yucca Mountain, the preferred location of these surface facilities. This interim report presents the preliminary results of this work

  18. New shipyard layout design for the preliminary phase & case study for the green field project

    Science.gov (United States)

    Song, Young Joo; Woo, Jong Hun

    2013-03-01

    For several decades, Asian nations such as Korea, Japan and China have been leading the shipbuilding industry since the decline in Europe and America. However, several developing countries such as India, Brazil, etc. are going to make an entrance into the shipbuilding industry. These developing countries are finding technical partners or information providers because they are in situation of little experiences and technologies. Now, the shipbuilding engineering companies of shipbuilding advanced countries are getting a chance of engineering business against those developing countries. The starting point of this business model is green field project for the construction of new shipyard. This business model is started with a design of the shipyard layout. For the conducting of the shipyard layout design, four kinds of engineering parts are required. Those are civil engineering, building engineering, utility engineering and production layout engineering. Among these parts, production layout engineering is most important because its result is the foundation of the other engineering parts and it determines the shipyard capacity during the shipyard operation lifecycle. Previous researches about the shipyard layout design are out of the range from the business requirements because most research cases are in the tower of ivory, which means that there are little consideration of real ship and shipbuilding operation. In this paper, a shipyard layout design for preliminary phase is conducted for the target of newly planned shipyard at Venezuela of South America with an integrated method that is capable of dealing with actual master data from the shipyard. The layout design method of this paper is differentiated from the previous researches in that the actual product data from the target ship and the actual shipbuilding operation data are used for the required area estimation.

  19. New shipyard layout design for the preliminary phase & case study for the green field project

    Directory of Open Access Journals (Sweden)

    Young Joo Song

    2013-03-01

    Full Text Available For several decades, Asian nations such as Korea, Japan and China have been leading the shipbuilding industry since the decline in Europe and America. However, several developing countries such as India, Brazil, etc. are going to make an entrance into the shipbuilding industry. These developing countries are finding technical partners or information providers because they are in situation of little experiences and technologies. Now, the shipbuilding engineering companies of shipbuilding advanced countries are getting a chance of engineering business against those developing countries. The starting point of this business model is green field project for the construction of new shipyard. This business model is started with a design of the shipyard layout. For the conducting of the shipyard layout design, four kinds of engineering parts are required. Those are civil engineering, building engineering, utility engineering and production layout engineering. Among these parts, production layout engineering is most important because its result is the foundation of the other engineering parts and it determines the shipyard capacity during the shipyard operation lifecycle. Previous researches about the shipyard layout design are out of the range from the business requirements because most research cases are in the tower of ivory, which means that there are little consideration of real ship and shipbuilding operation. In this paper, a shipyard layout design for preliminary phase is conducted for the target of newly planned shipyard at Venezuela of South America with an integrated method that is capable of dealing with actual master data from the shipyard. The layout design method of this paper is differentiated from the previous researches in that the actual product data from the target ship and the actual shipbuilding operation data are used for the required area estimation.

  20. 76 FR 25322 - Oklahoma Rose Water LLC; Notice of Preliminary Permit Application Accepted for Filing and...

    Science.gov (United States)

    2011-05-04

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Project No. 13854-000] Oklahoma Rose Water LLC; Notice of Preliminary Permit Application Accepted for Filing and Soliciting Comments, Motions To Intervene, and Competing Applications On September 30, 2010, Oklahoma Rose Water LLC filed an...

  1. 75 FR 78235 - Dodge Mill Realty, LLC; Notice of Preliminary Permit Application Accepted for Filing and...

    Science.gov (United States)

    2010-12-15

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Project No. 13890-000] Dodge Mill Realty, LLC; Notice of Preliminary Permit Application Accepted for Filing and Soliciting Comments, Motions To Intervene, and Competing Applications December 8, 2010. On December 3, 2010, Dodge Mill Realty...

  2. 78 FR 71601 - KC Small Hydro LLC; Advanced Hydropower, Inc.; Notice of Preliminary Permit Application Accepted...

    Science.gov (United States)

    2013-11-29

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Project Nos. 14521-001, 14561-000] KC Small Hydro LLC; Advanced Hydropower, Inc.; Notice of Preliminary Permit Application Accepted for Filing and Soliciting Comments, Motions To Intervene, and Competing Applications On May 13, 2013, KC Scoby...

  3. A Preliminary Review of U.S. Forest Service Business Practices To Authorize Special Uses, Including Energy Infrastructure Projects, on National Forest System Lands

    Energy Technology Data Exchange (ETDEWEB)

    Wescott, K. L. [Argonne National Lab. (ANL), Argonne, IL (United States); May, J. E. [Argonne National Lab. (ANL), Argonne, IL (United States); Moore, H. R. [Argonne National Lab. (ANL), Argonne, IL (United States); Brunner, D. L. [Argonne National Lab. (ANL), Argonne, IL (United States)

    2014-09-01

    The U.S. Forest Service (USFS) Special Uses-Lands Program is in jeopardy. Although this program, authorized in Title 36, Part 251, of the U.S. Code of Federal Regulations (36 CFR Part 251), ranks among the top four revenue-generating programs for use of National Forest System (NFS) lands, along with the Timber, Minerals, and Special Uses-Recreation Programs, the Special Uses-Lands Program is in a state of neglect. Repeated cuts in funding (a decrease of 26% from fiscal years 2010 to 2014) are adversely affecting staffing and training, which in turn is affecting timely permit processing and ultimately the public’s ability to use and benefit from NFS lands. In addition, highly experienced staff with valuable institutional knowledge of the program have begun to retire. The ability of the program to function under these dire circumstances can be attributed to the dedication of Special Uses staff to the program and their commitment to the public. The initial focus of this report was to identify opportunities for improving performance of permitting and review for large energy infrastructure-related projects. However, it became clear during this analysis that these projects are generally adequately staffed and managed. This is due in large part to the availability of cost-recovery dollars and the high-profile nature of these projects. However, it also became apparent that larger issues affecting the bulk of the work of the Special Uses-Lands Program need to be addressed immediately. This report is a preliminary examination of the state of the Special Uses-Lands Program and focuses on a few key items requiring immediate attention. Further investigation through case studies is recommended to dig deeper into the Special Uses-Lands Program business process to determine the most costeffective strategies for streamlining the overall process and the metrics by which performance can be evaluated, including for the permitting and tracking of energy infrastructure projects.

  4. Chapter F: Preliminary Bibliography of Lacustrine Diatomite Deposits in the Western United States and Related Topics

    Science.gov (United States)

    Bolm, Karen S.; Wallace, Alan R.; Moyle, Phillip R.; Bliss, James D.; Orris, Greta J.

    2003-01-01

    Introduction As part of the assessment of lacustrine diatomite resources in the Western United States (fig. 1), U.S. Geological Survey (USGS) project members conducted a review of literature relating to the formation, location, and nature of deposits in the study area. This preliminary bibliography consists of selected publications to identify, locate, and describe the deposits to be studied, to characterize common geologic factors about the deposits, and to better understand the factors that control their formation, preservation, or destruction. The bibliography also serves as a resource for other workers to research the topic. References included in the preliminary bibliography were gathered by searching existing bibliographic data bases and library collections. Project researchers also contributed references that they found during the course of their work. This bibliography should be considered a working document that will grow as research and literature searches continue. Clearly, many significant publications may be missing from this preliminary list; therefore, USGS staff members intend to issue a revised bibliography as project work progresses. To assure completeness, input from other researchers and industry is welcome. Although the focus of this bibliography is lacustrine diatomite deposits of the Western United States, additional references that provide a foundation of knowledge for the study of diatomites, diatoms, and diatom-related processes (ecology, geology, geochemistry) and for the uses and behavior of diatomite have also been included. An index of keywords has been added to this bibliography, designed to help the user locate reports by topic or by geographic location. The letter 'A' following a number indicates that the report referenced is an abstract.

  5. 75 FR 78236 - Pennamaquan Tidal Power, LLC; Notice of Preliminary Permit Application Accepted for Filing and...

    Science.gov (United States)

    2010-12-15

    ... Tidal Power, LLC; Notice of Preliminary Permit Application Accepted for Filing and Soliciting Comments, Motions To Intervene, and Competing Applications December 8, 2010. On November 22, 2010, Pennamaquan Tidal... Act (FPA), proposing to study the feasibility of the Pennamaquan Tidal Power Plant Project to be...

  6. 75 FR 18190 - New Jersey Water Supply Authority; Notice of Preliminary Permit Application Accepted for Filing...

    Science.gov (United States)

    2010-04-09

    ... Contact: Edward Buss, P.E., New Jersey Water Supply Authority, 1851 State Hwy. 31, Clinton, NJ 08800, (908... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Project No. 13399-000] New Jersey Water Supply Authority; Notice of Preliminary Permit Application Accepted for Filing and Soliciting Comments...

  7. 75 FR 11153 - Main Mill Street Investments, LLC; Notice of Preliminary Permit Application Accepted for Filing...

    Science.gov (United States)

    2010-03-10

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Project No. 13631-000] Main Mill Street..., Motions To Intervene, and Competing Applications March 1, 2010. On November 16, Main Mill Street Investments, LLC (Main Mill Street Investments) filed an application for a preliminary permit, pursuant to...

  8. Yucca Mountain transportation routes: Preliminary characterization and risk analysis; Volume 2, Figures [and] Volume 3, Technical Appendices

    Energy Technology Data Exchange (ETDEWEB)

    Souleyrette, R.R. II; Sathisan, S.K.; di Bartolo, R. [Nevada Univ., Las Vegas, NV (United States). Transportation Research Center

    1991-05-31

    This report presents appendices related to the preliminary assessment and risk analysis for high-level radioactive waste transportation routes to the proposed Yucca Mountain Project repository. Information includes data on population density, traffic volume, ecologically sensitive areas, and accident history.

  9. Project management approach for the Waste Area Grouping 6 Closure/Remediation Project at Oak Ridge National Laboratory, Oak Ridge, Tennessee

    International Nuclear Information System (INIS)

    1992-07-01

    This document has been developed as a preliminary definition of the Waste Area Grouping (WAG) 6 Closure Project Management Approach. The purpose of this document is to identify the roles and responsibilities of the various project team members and to identify the project scope, schedule and budget. This document is intended to be a living document. As information develops, this document will be revised to create a WAG 6 Project Management Plan (PMP). The PMP will provide additional focus to the information contained in this document. The information required will be available as the selected alternative for remediation of WAG 6 is approved and Remedial Action Plans are conceptualized. This document has been reviewed against, and is intended to be consistent with, the Environmental Restoration Program Management Plan

  10. PACTEL OECD project planning (PACO). PACTEL OECD project planning

    Energy Technology Data Exchange (ETDEWEB)

    Kouhia, V.; Purhonen, H. [Lappeenranta University of Technology (Finland)

    2004-07-01

    OECD launched the SETH project to investigate issues relevant for accident prevention and management and to ensure the existence of integral thermal hydraulic test facilities. The facilities included in the SETH project are PKL from Germany and PANDA from Switzerland. At the early stages of the SETH project an idea was raised to exploit the PACTEL facility in a similar OECD project. Without any external funding the analytical work in the required extent would not be possible within Lappeenranta University of Technology, the party responsible of operating PACTEL. This fact directed the PACO project proposal to be conducted for the SAFIR programme. The aim of the PACO project is to prepare a project proposal to OECD of a PACTEL related project. To attain this objective some preliminary analyses have to be performed to ensure the relevancy of the proposed topic. The low power situation, i.e. midloop state was chosen to be the topic in the PACO studies and project planning basis. The plan is to use PACTEL to examine vertical steam generator behaviour during the midloop operation and the following loss of residual heat removal system transient. Such a possibility is acknowledged with special alterations to PACTEL. The APROS code version 5.04.07 was selected as a tool for the preanalyses. The virtual simulation of the chosen experimental situation would give a preconception on the phenomena to be expected and the progression of the transient. Originally the PACO project was planned to continue only for a few months, ending up with the project proposal to OECD during the summer time 2004. During the pre-calculation process it became obvious that the time expected was not enough to establish good pre-calculation results. The reasons for this relates to time used to learn and adapt the use of the chosen code, improvements and corrections in modelling as well as the code ability to manage the special conditions defined for the project topic. Another aspect on completing a

  11. Rural telemedicine project in northern New Mexico

    Energy Technology Data Exchange (ETDEWEB)

    Zink, S.; Hahn, H.; Rudnick, J.; Snell, J.; Forslund, D. [Los Alamos National Lab., NM (United States); Martinez, P. [Northern New Mexico Community Coll., Espanola, NM (United States)

    1998-12-31

    A virtual electronic medical record system is being deployed over the Internet with security in northern New Mexico using TeleMed, a multimedia medical records management system that uses CORBA-based client-server technology and distributed database architecture. The goal of the NNM Rural Telemedicine Project is to implement TeleMed into fifteen rural clinics and two hospitals within a 25,000 square mile area of northern New Mexico. Evaluation of the project consists of three components: job task analysis, audit of immunized children, and time motion studies. Preliminary results of the evaluation components are presented.

  12. A Preliminary Study on Time Projection Chamber Simulation for Fission Cross Section Measurements with Geant4

    International Nuclear Information System (INIS)

    Kim, Jong Woon; Lee, Youngouk; Kim, Jae Cheon

    2014-01-01

    We present the details of the TPC simulation with Geant4 and show the results. TPC can provide more information than a fission chamber in that it is possible to distinguish different particle types. Simulations are conducted for uranium and plutonium targets with 20MeV neutrons. The simulation results are compared with the reference and show reasonable results. This is the first phase of study for realizing a TPC in the NFS at RAON, and we have more work to do, such as applying an electric field, signal processing in the simulation, and manufacturing of a TPC. The standard in fission cross section measurement is a fission chamber. It is basically just two parallel plates separated by a few centimeters of gas. A power supply connected to the plates sets up a moderate electric field. The target is deposited onto one of the plates. When fission occurs, the fragments ionize the gas, and the electric field causes the produced electrons to drift to the opposite plate, which records the total energy deposited in the chamber. A Time Projection Chamber (TPC) is a gas ionization detector similar to a fission chamber. However, it can measure the charged particle trajectories in the active volume in three dimensions by adding several readouts on the pad plane (fission chamber has only one readout one a pad plane). The specific ionization for each particle track enables the TPC to distinguish different particle types. A TPC will be used for fission cross section measurements in the Neutron Science Facility (NSF) at RAON. As a preliminary study, we present details of TPC simulation with Geant4 and discuss the results

  13. Hanford Waste Vitrification Plant: Preliminary description of waste form and canister

    International Nuclear Information System (INIS)

    Mitchell, D.E.

    1986-01-01

    In July 1985, the US Department of Energy's Office of Civilian Radioactive Waste Management established the Waste Acceptance Process as the means by which defense high-level waste producers, such as the Hanford Waste Vitrification Plant, will develop waste acceptance requirements with the candidate geologic repositories. A complete description of the Waste Acceptance Process is contained in the Preliminary Hanford Waste Vitrification Plant Waste Form Qualification Plan. The Waste Acceptance Process defines three documents that high-level waste producers must prepare as a part of the process of assuming that a high-level waste product will be acceptable for disposal in a geologic repository. These documents are the Description of Waste Form and Canister, Waste Compliance Plan, and Waste Qualification Report. This document is the Hanford Waste Vitrification Plant Preliminary Description of Waste Form and Canister for disposal of Neutralized Current Acid Waste. The Waste Acceptance Specifications for the Hanford Waste Vitrification Plant have not yet been developed, therefore, this document has been structured to corresponds to the Waste Acceptance Preliminary Specifications for the Defense Waste Processing Facility High-Level Waste Form. Not all of the information required by these specifications is appropriate for inclusion in this Preliminary Description of Waste Form and Canister. Rather, this description is limited to information that describes the physical and chemical characteristics of the expected high-level waste form. The content of the document covers three major areas: waste form characteristics, canister characteristics, and canistered waste form characteristics. This information will be used by the candidate geologic repository projects as the basis for preliminary repository design activities and waste form testing. Periodic revisions are expected as the Waste Acceptance Process progresses

  14. The SNS target station preliminary Title I shielding analyses

    International Nuclear Information System (INIS)

    Johnson, J.O.; Santoro, R.T.; Lillie, R.A.; Barnes, J.M.; McNeilly, G.S.

    2000-01-01

    The Department of Energy (DOE) has given the Spallation Neutron Source (SNS) project approval to begin Title I design of the proposed facility to be built at Oak Ridge National Laboratory (ORNL). During the conceptual design phase of the SNS project, the target station bulk-biological shield was characterized and the activation of the major targets station components was calculated. Shielding requirements were assessed with respect to weight, space, and dose-rate constraints for operating, shut-down, and accident conditions utilizing the SNS shield design criteria, DOE Order 5480.25, and requirements specified in 10 CFR 835. Since completion of the conceptual design phase, there have been major design changes to the target station as a result of the initial shielding and activation analyses, modifications brought about due to engineering concerns, and feedback from numerous external review committees. These design changes have impacted the results of the conceptual design analyses, and consequently, have required a re-investigation of the new design. Furthermore, the conceptual design shielding analysis did not address many of the details associated with the engineering design of the target station. In this paper, some of the proposed SNS target station preliminary Title I shielding design analyses will be presented. The SNS facility (with emphasis on the target station), shielding design requirements, calculational strategy, and source terms used in the analyses will be described. Preliminary results and conclusions, along with recommendations for additional analyses, will also be presented. (author)

  15. Preliminary benefit-cost analysis of the Fast Flux Test Facility (FFTF) power addition

    International Nuclear Information System (INIS)

    Callaway, J.M.; Lezberg, A.J.; Scott, M.J.; Tawil, J.J.

    1984-07-01

    The primary objective of this report is to conduct a preliminary benefit-cost study for the proposed power addition to FFTF to determine whether the project is cost-effective. If the project is authorized, construction will begin in 1986 and end in 1991. Full power operation is scheduled to begin in 1991 and a project life of 20 years is assumed. The undiscounted cost during the construction period of the FFTF power addition is estimated to be approximately $117 million over the construction period (1984 dollars). An additional $3 million is estimated as the opportunity cost - or value of these resources in their most favorable alternative use - of surplus FFTF equipment and unused CRBR equipment, including materials for steam generator fabrication. The annual operating and maintenance cost of the project is estimated to be about $2.1 million in 1984 dollars. 20 references

  16. 75 FR 2128 - Basin Farm Renewable, LLC; Notice of Preliminary Permit Application Accepted for Filing and...

    Science.gov (United States)

    2010-01-14

    ... Renewable, LLC; Notice of Preliminary Permit Application Accepted for Filing and Soliciting Comments... Renewable, LLC filed an application, pursuant to section 4(f) of the Federal Power Act, proposing to study the feasibility of the Basin Farm Renewable Energy Project, to be located on Saxtons River, in...

  17. 75 FR 21289 - Oregon Wave Energy Partners I, LLC; Notice of Preliminary Permit Application Accepted for Filing...

    Science.gov (United States)

    2010-04-23

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Project No. 12749-002] Oregon Wave Energy Partners I, LLC; Notice of Preliminary Permit Application Accepted for Filing and Soliciting.... Charles F. Dunleavy, Oregon Wave Energy Partners I, LLC, 1590 Reed Road, Pennington, NJ 08534. FERC...

  18. DECOVALEX-THMC Project. Task A. Influence of near field coupled THM phenomena on the performance of a spent fuel repository. Report of Task A1: Preliminary scoping calculations

    Energy Technology Data Exchange (ETDEWEB)

    Nguyen, Son (ed.) [Canadian Nuclear Safety Commission (Canada); Lanru Jing (ed.) [Royal Institute of Technology, Stockholm (Sweden); Boergesson, Lennart [Clay Technology AB, Lund (Sweden); Chijimatzu, Masakazu [Hazama Corporation (Japan); Jussila, Petri [Helsinki Univ. of Technology, Helsinki (Finland); Rutqvist, Jonny [Lawrence Berkeley National Laboratory CA (United States)

    2007-02-15

    The DECOVALEX-THMC project is an ongoing international co-operative project that was stared in 2004 to support the development of mathematical models of coupled Thermal (T), Hydrological (H), Mechanical (M) and Chemical (C) processes in geological media for siting potential nuclear fuel waste repositories. The general objective is to characterise and evaluate the coupled THMC processes in the near field and far field of a geological repository and to assess their impact on performance assessment: - during the three phases of repository development: excavation phase, operation phase and post-closure phase; - for three different rocks types: crystalline, argillaceous and tuff; - with specific focus on the issues of: Excavation Damaged Zone (EDZ), permanent property changes of rock masses, and glaciation and permafrost phenomena. The project involves a large number of research teams supported by radioactive waste management agencies or governmental regulatory bodies in Canada, China, Finland, France, Germany, Japan, Sweden and USA, who conducted advanced studies and numerical modelling of coupled THMC processes under five tasks. This report presents the definition of the first phase, Task A-1, of the Task A of the project. The task is a working example of how interaction between THMC modelling and SA analysis could be performed. Starting with the technical definition of the Task A, the report presents the results of preliminary THM calculations with a purpose of an initial appreciation of the phenomena and material properties that must be better understood in subsequent phases. Many simplifications and assumptions were introduced and the results should be considered under these assumptions. Based on the evaluation of the multiple teams' results, a few points of concern were identified that may guide the successive phases of Task A studies: 1. The predicted maximum total stress in the MX-80 bentonite could slightly exceed the 15 MPa design pressure for the

  19. DECOVALEX-THMC Project. Task A. Influence of near field coupled THM phenomena on the performance of a spent fuel repository. Report of Task A1: Preliminary scoping calculations

    International Nuclear Information System (INIS)

    Nguyen, Son; Lanru Jing; Boergesson, Lennart; Chijimatzu, Masakazu; Jussila, Petri; Rutqvist, Jonny

    2007-02-01

    The DECOVALEX-THMC project is an ongoing international co-operative project that was stared in 2004 to support the development of mathematical models of coupled Thermal (T), Hydrological (H), Mechanical (M) and Chemical (C) processes in geological media for siting potential nuclear fuel waste repositories. The general objective is to characterise and evaluate the coupled THMC processes in the near field and far field of a geological repository and to assess their impact on performance assessment: - during the three phases of repository development: excavation phase, operation phase and post-closure phase; - for three different rocks types: crystalline, argillaceous and tuff; - with specific focus on the issues of: Excavation Damaged Zone (EDZ), permanent property changes of rock masses, and glaciation and permafrost phenomena. The project involves a large number of research teams supported by radioactive waste management agencies or governmental regulatory bodies in Canada, China, Finland, France, Germany, Japan, Sweden and USA, who conducted advanced studies and numerical modelling of coupled THMC processes under five tasks. This report presents the definition of the first phase, Task A-1, of the Task A of the project. The task is a working example of how interaction between THMC modelling and SA analysis could be performed. Starting with the technical definition of the Task A, the report presents the results of preliminary THM calculations with a purpose of an initial appreciation of the phenomena and material properties that must be better understood in subsequent phases. Many simplifications and assumptions were introduced and the results should be considered under these assumptions. Based on the evaluation of the multiple teams' results, a few points of concern were identified that may guide the successive phases of Task A studies: 1. The predicted maximum total stress in the MX-80 bentonite could slightly exceed the 15 MPa design pressure for the container

  20. Preliminary study of a flux converter for experimental reactor

    International Nuclear Information System (INIS)

    Malouch, M.F.

    1998-01-01

    The purpose of this project is to define the characteristics of a flux converter dedicated to increase the fast neutron flux in irradiation devices placed in the core of Osiris experimental reactor. This preliminary work has dealt with the neutronic and thermal-hydraulic aspects of this problem. The synthesis of the results produced by the codes APOLLO2, DAIXY, MERCURE5.3 and FLICA-3M shows that a cylindrical converter equipped with 5 fissile rings can enhance the fast flux by a 35% factor in an experimental device set in its center. (A.C.)

  1. Failure mode analysis of preliminary design of ITER divertor impurity monitor

    International Nuclear Information System (INIS)

    Kitazawa, Sin-iti; Ogawa, Hiroaki

    2016-01-01

    Highlights: • Divertor impurity influx monitor for ITER (DIM) is procured by JADA. • DIM is designed to observe light from nuclear fusion plasma directly. • DIM is under preliminary design phase. • Failure mode of DIM was prepared for RAMI analysis. • RAMI analysis on DIM was performed to reduce technical risks. - Abstract: The objective of the divertor impurity influx monitor (DIM) for ITER is to measure the parameters of impurities and hydrogen isotopes (tritium, deuterium, and hydrogen) in divertor plasma using visible and UV spectroscopic techniques in the 200–1000 nm wavelength range. In ITER, special provisions are required to ensure accuracy and full functionality of the diagnostic components under harsh conditions (high temperature, high magnetic field, high vacuum condition, and high radiation field). Japan Domestic Agency is preparing the preliminary design of the ITER DIM system, which will be installed in the upper, equatorial and lower ports. The optical and mechanical designs of the DIM are conducted to fit ITER’s requirements. The optical and mechanical designs meet the requirements of spatial resolution. Some auxiliary systems were examined via prototyping. The preliminary design of the ITER DIM system was evaluated by RAMI analysis. The availability of the designed system is adequately high to satisfy the project requirements. However, some equipment does not have certain designs, and this may cause potential technical risks. The preliminary design should be modified to reduce technical risks and to prepare the final design.

  2. Reference terms for the capitalisation study of Mali domestic biogas (BFM) and Climate and Energy in Western Africa (CEnAO) projects. Projects financed by the FISONG arrangement of the French Agency for Development (AFD)

    International Nuclear Information System (INIS)

    2014-01-01

    The BFM project (or domestic biogas project in Mali) project concerns the installation of 100 bio-digesters in Mali, and the CenAO one concerns the building up of wood-energy sector in Bamako. This report first presents these both projects, and then presents the capitalisation study, its objectives (global and specific objectives). It presents the study organisation: method and approach (preliminary phase, realisation, conclusion and recommendation), required abilities for the assessment, duration, documents to be produced

  3. Development of human factors engineering guide for nuclear power project

    International Nuclear Information System (INIS)

    Wu Dangshi; Sheng Jufang

    1997-01-01

    'THE PRACTICAL GUIDE FOR APPLICATION OF HUMAN FACTORS ENGINEERING TO NUCLEAR POWER PROJECT (First Draft, in Chinese)', which was developed under a research program sponsored by National Nuclear Safety Administration (NNSA) is described briefly. It is hoped that more conscious, more systematical and more comprehensive application of Human Factors Engineering to the nuclear power projects from the preliminary feasibility studies up to the commercial operation will benefit the safe, efficient and economical operations of nuclear power plants in China

  4. The Wiluna Uranium Project, Western Australia: Bringing a new project to the market

    International Nuclear Information System (INIS)

    Guthrie, V.

    2014-01-01

    The Wiluna Uranium Project is the first uranium mine in Western Australia to receive Government environmental approval since government policy was changed in 2008 to allow uranium mining in Western Australia. Located 960 km northeast of Perth in remote central Western Australia, the Wiluna Project comprises 76.5 million pounds U_3O_8 [~29,000 tU] in six shallow, calcrete-hosted carnotite uranium deposits. Mining is planned at a rate of 1.3 million tonnes annually to produce 2 million pounds U_3O_8 [~770 tU] production using an alkali leach process. The Project requires initial capital investment of AUD$315M and has an operating cost of US$29-31 per pound [~75-~80 USD/kgU]. During the four years it has taken to gain environmental approval, Toro also progressed technical studies to validate the economic and technical viability of the Project. These included the initial Preliminary Feasibility (PFS) to define the processing train; mining optimisation studies, a Resource Evaluation Pit (REP) and a commercial scale Pilot Plant to verify the mining and processing technologies; and finally, Phase 1 of the Definitive Feasibility Study (DFS) which focussed on the processing plant design. (author)

  5. WSSRAP [Weldon Spring Site Remedial Action Project] quarry preliminary engineering report

    International Nuclear Information System (INIS)

    1990-01-01

    The removal, transport, and temporary storage of radiologically and chemically contaminated bulk waste from the Weldon Spring Quarry will be accomplished by dividing the work into three subcontract packages. The major portion of the work will come under the bulk waste excavation package; construction of a temporary storage area (TSA) at the Weldon Spring Chemical Plant and of a haul road between the quarry and the TSA comprise the other two packages. Cost estimates to complete the removal range from $5 million to $9.4 million due to a high degree of uncertainty regarding both the productivity of the excavating equipment and the effectiveness of planned dewatering efforts. Quarry wastes will be substantially dewatered and the water treated before discharge. Waste will be excavated in three phases, using conventional construction equipment, with preliminary sorting of waste at the quarry before transport to the TSA. Special attention will be given to controlling the spread of contamination by careful monitoring and control of surface and groundwater drainage and of particulate and radiological contamination of the air. 6 refs., 21 figs., 8 tabs

  6. Expansive Learning in Construction Projects - a Contradiction in terms?

    DEFF Research Database (Denmark)

    Klitgaard, Anne; Nissen, Søren Bülow; Beck, Frederikke

    2016-01-01

    This research is a preliminary study performed as part of a primary research into expansive learning in interorganizational network set up to solve a construction project. The construction industry has long had issues about productivity, which can be an indication of lack of learning. A case study...... acquisition and participation but not by expansive learning. The construction industry needs to accept that the learning generated from projects will be limited to learning by acquisition and participation. The interorganizational network cannot facilitate expansive learning while working on object......-fixed projects. Research in construction management fails to generate and document knowledge because of the limitations of case studies....

  7. 40 CFR 262.103 - What is the scope of the laboratory environmental management standard?

    Science.gov (United States)

    2010-07-01

    ... environmental management standard? 262.103 Section 262.103 Protection of Environment ENVIRONMENTAL PROTECTION... University Laboratories XL Project-Laboratory Environmental Management Standard § 262.103 What is the scope of the laboratory environmental management standard? The Laboratory Environmental Management Standard...

  8. 40 CFR 265.1080 - Applicability.

    Science.gov (United States)

    2010-07-01

    ... requirements of § 265.1090(c). (f) This section applies only to the facility commonly referred to as the OSi... Water 8 model or other model agreed to by the Sistersville Plant, EPA and WVDEP) under Project XL with...

  9. Radiology workstation for mammography: preliminary observations, eyetracker studies, and design

    Science.gov (United States)

    Beard, David V.; Johnston, Richard E.; Pisano, Etta D.; Hemminger, Bradley M.; Pizer, Stephen M.

    1991-07-01

    For the last four years, the UNC FilmPlane project has focused on constructing a radiology workstation facilitating CT interpretations equivalent to those with film and viewbox. Interpretation of multiple CT studies was originally chosen because handling such large numbers of images was considered to be one of the most difficult tasks that could be performed with a workstation. The authors extend the FilmPlane design to address mammography. The high resolution and contrast demands coupled with the number of images often cross- compared make mammography a difficult challenge for the workstation designer. This paper presents the results of preliminary work with workstation interpretation of mammography. Background material is presented to justify why the authors believe electronic mammographic workstations could improve health care delivery. The results of several observation sessions and a preliminary eyetracker study of multiple-study mammography interpretations are described. Finally, tentative conclusions of what a mammographic workstation might look like and how it would meet clinical demand to be effective are presented.

  10. Preliminary study of synthesis gas production from water electrolysis, using the ELECTROFUEL® concept

    International Nuclear Information System (INIS)

    Guerra, L.; Gomes, J.; Puna, J.; Rodrigues, J.

    2015-01-01

    This paper describes preliminary work on the generation of synthesis gas from water electrolysis using graphite electrodes without the separation of the generated gases. This is an innovative process, that has no similar work been done earlier. Preliminary tests allowed to establish correlations between the applied current to the electrolyser and flow rate and composition of the generated syngas, as well as a characterisation of generated carbon nanoparticles. The obtained syngas can further be used to produce synthetic liquid fuels, for example, methane, methanol or DME (dimethyl ether) in a catalytic reactor, in further stages of a present ongoing project, using the ELECTROFUEL ® concept. The main competitive advantage of this project lies in the built-in of an innovative technology product, from RE (renewable energy) power in remote locations, for example, islands, villages in mountains as an alternative for energy storage for mobility constraints. - Highlights: • Generation of synthesis gas from water electrolysis without separation of gases. • Obtained syngas: 7.7% CO; 10.3% O 2 and 2.0% CO 2 . • Syngas can further be used to produce synthetic liquid fuels

  11. ANALISIS ELEMEN-ELEMEN BRAND EQUITY PADA PRODUK KARTU SELULER PRABAYAR SIMPATI, IM3, DAN XL DI KALANGAN MAHASISWA S1 UNIVERSITAS DIPONEGORO

    Directory of Open Access Journals (Sweden)

    Arfan Bakhtiar

    2015-11-01

    Full Text Available Era globalisasi menjanjikan suatu peluang dan tantangan bisnis baru bagi perusahaan yang beroperasi di Indonesia. Salah satu industri yang sangat ketat persaingannya adalah industri telekomunikasi. Di Indonesia saat ini terdapat tiga perusahaan GSM yang menguasai pasar yang bergerak dalam industri ini, perusahaan itu adalah IM3 yang dikeluarkan oleh PT. Indosat TBK, XL yang dikeluarkan PT. Excelcomindo Pratama dan Simpati yang dikeluarkan oleh PT. Telekomunikasi Seluler. Penelitian ini bertujuan untuk meneliti elemen-elemen ekuitas merek dari ketiga merek kartu telepon tersebut. Manfaat yang diperoleh dari penelitian ini adalah memberikan informasi kepada para pembaca mengenai produk kartu telepon apa yang paling diingat konsumen asosiasi-asosiasi apa saja yang melekat pada kartu-kartu telepon tersebut, produk kartu telepon apa yang memiliki tingkat loyalitas paling tinggi, serta bagaimana persepsi kualitas konsumen terhadap kartu-kartu tersebut. Pengujian hipotesis dalam penelitian ini akan menggunakan Uji Cohran. Dari hasil penelitian yang dilakukan pada tiap elemen-elemennya, didapat bahwa produk kartu Simpati adalah produk yang memiliki tingkat brand awareness paling tinggi, asosiasi produk yang paling banyak adalah Simpati dengan 7 asosiasi, tingkat loyalitas konsumen pengguna kartu telepon yang paling tinggi adalah kartu Simpati, serta kartu telepon yang memiliki brand perceived quality yang diukur berdasarkan performance dan importancenya adalah kartu Simpati.   Kata kunci: brand association; brand awareness; brand equity;brand loyalty; perceived quality Abstract The globalization era provides new business opportunities and challenges for industries operating in Indonesia. One of the industries that has tight competition is telecommunications industry. In Indonesia, there are currently three GSM industries that dominate the market that engaged in the industry. They are IM3, owned by Indosat TBK Ltd., XL, owned by Excelcomindo Pratama Ltd

  12. 76 FR 34975 - U.S. Farmers, LLC; Notice of Preliminary Permit Application Accepted for Filing and Soliciting...

    Science.gov (United States)

    2011-06-15

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Project No. 14102-000] U.S. Farmers, LLC; Notice of Preliminary Permit Application Accepted for Filing and Soliciting Comments, Motions To Intervene, and Competing Applications On February 22, 2011, U.S. Farmers, LLC filed an application for a...

  13. Medical microbiological analysis of Apollo-Soyuz test project crewmembers

    Science.gov (United States)

    Taylor, G. R.; Zaloguev, S. N.

    1976-01-01

    The procedures and results of the Microbial Exchange Experiment (AR-002) of the Apollo-Soyuz Test Project are described. Included in the discussion of procedural aspects are methods and materials, in-flight microbial specimen collection, and preliminary analysis of microbial specimens. Medically important microorganisms recovered from both Apollo and Soyuz crewmen are evaluated.

  14. KALIMER preliminary conceptual design report

    Energy Technology Data Exchange (ETDEWEB)

    Hahn, Do Hee; Kim, Y. J.; Kim, Y. G. and others

    2000-08-01

    This report, which summarizes the result of preliminary conceptual design activities during Phase 1, follows the format of safety analysis report. The purpose of publishing this report is to gather all of the design information developed so far in a systematic way so that KALIMER designers have a common source of the consistent design information necessary for their future design activities. This report will be revised and updated as design changes occur and more detailed design specification is developed during Phase 2. Chapter 1 describes the KALIMER Project. Chapter 2 includes the top level design requirements of KALIMER and general plant description. Chapter 3 summarizes the design of structures, components, equipment and systems. Specific systems and safety analysis results are described in the remaining chapters. Appendix on the HCDA evaluation is attached at the end of this report.

  15. KALIMER preliminary conceptual design report

    International Nuclear Information System (INIS)

    Hahn, Do Hee; Kim, Y. J.; Kim, Y. G. and others

    2000-08-01

    This report, which summarizes the result of preliminary conceptual design activities during Phase 1, follows the format of safety analysis report. The purpose of publishing this report is to gather all of the design information developed so far in a systematic way so that KALIMER designers have a common source of the consistent design information necessary for their future design activities. This report will be revised and updated as design changes occur and more detailed design specification is developed during Phase 2. Chapter 1 describes the KALIMER Project. Chapter 2 includes the top level design requirements of KALIMER and general plant description. Chapter 3 summarizes the design of structures, components, equipment and systems. Specific systems and safety analysis results are described in the remaining chapters. Appendix on the HCDA evaluation is attached at the end of this report

  16. Barkhausen Effect and Acoustic Emission in a Metallic Glass - Preliminary Results

    International Nuclear Information System (INIS)

    Lopez Sanchez, R.; Lopez Pumarega, M.I.; Armeite, M.; Piotrkowski, R.; Ruzzante, J.E.

    2004-01-01

    Magneto Acoustic Emission, which is Barkhausen Noise (BN) and Acoustic Emission (AE), depends on microstructure and existing residual stresses in magnetic materials. Preliminary results obtained by magnetization along two perpendicular directions on a metal glass foil are presented. Signals were analyzed with Statistic, Fast Fourier and Wavelet methods. Results are part of a Joint Research Project of the Faculty of Science, Cantabria University, Spain, and the Elastic Waves Group of the National Atomic Energy Commission, Argentina

  17. Preliminary Monthly Climatological Summaries

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Preliminary Local Climatological Data, recorded since 1970 on Weather Burean Form 1030 and then National Weather Service Form F-6. The preliminary climate data pages...

  18. On Best Practices for Risk Management in Complex Projects

    Directory of Open Access Journals (Sweden)

    Dan BENTA

    2011-01-01

    Full Text Available Risk management shall be proactive. This is one of the key preliminaries to cope with the challenges of complex projects. An overarching and consistent view on project risks and uncertainties is necessary to follow a holistic approach in project risk management. Uncertainty is inevitable since projects are unique and temporary undertakings based on assumptions and constraints, delivering project results to multiple stakeholders with different requirements. Project management can be seen as an attempt to control this uncertain environment, through the use of structured and disciplined techniques such as estimating, planning, cost control, task allocation, earned value analysis, monitoring, and review meetings. Each of these elements of project management has a role in defining or controlling inherent variability in projects. Project risk management provides approaches by which uncertainty can be understood, assessed, and managed within projects. A number of associations (e.g., Project Management Institute – PMI®, International Project Management Association – IPMA,or Network of Nordic Project Management Associations - NORDNET work constantly in acquiring, improving, and standardizing best practices in project management.Based on the industrial practice, this paper outlines strategies to identify, prioritize, and mitigate risks for achievement of project’ or organizational objectives.

  19. Preliminary design concepts for the advanced neutron source reactor systems

    International Nuclear Information System (INIS)

    Peretz, F.J.

    1988-01-01

    This paper describes the initial design work to develop the reactor systems hardware concepts for the advanced neutron source (ANS) reactor. This project has not yet entered the conceptual design phase; thus, design efforts are quite preliminary. This paper presents the collective work of members of the Oak Ridge National Laboratory, Martin Marietta Energy Systems, Inc., Engineering Division, and other participating organizations. The primary purpose of this effort is to show that the ANS reactor concept is realistic from a hardware standpoint and to show that project objectives can be met. It also serves to generate physical models for use in neutronic and thermal-hydraulic core design efforts and defines the constraints and objectives for the design. Finally, this effort will develop the criteria for use in the conceptual design of the reactor

  20. Managing uncertainty for sustainability of complex projects

    DEFF Research Database (Denmark)

    Brink, Tove

    2017-01-01

    Purpose – The purpose of this paper is to reveal how management of uncertainty can enable sustainability of complex projects. Design/methodology/approach – The research was conducted from June 2014 to May 2015 using a qualitative deductive approach among operation and maintenance actors in offshore...... wind farms. The research contains a focus group interview with 11 companies, 20 individual interviews and a seminar presenting preliminary findings with 60 participants. Findings – The findings reveal the need for management of uncertainty through two different paths. First, project management needs...... to join efforts. Research limitations/implications – Further research is needed to reveal the generalisability of the findings in other complex project contexts containing “unknown unknowns”. Practical implications – The research leads to the development of a tool for uncertainty management...

  1. Learning from participatory design projects across industries

    DEFF Research Database (Denmark)

    Broberg, Ole; Souza da Conceição, Carolina

    2017-01-01

    Summative Statement: A preliminary framework for participatory design projects (PDP) was developed based on a retrospective analysis of five PDPs across different industries. The framework may serve as a guidance for planning and conducting PDPs. Problem statement: A growing number of experiences...... with participatory design or participatory ergonomics projects have been gained within the field of macro-ergonomics. It is suggested that the Participatory Ergonomics Framework (PEF) validated by Haines et al. (2002) needs to be updated based on these experiences and hence more focussed on design activities....... Research Objective / Question: The objective of this study was to update and design-orient the PEF based on experiences with PDPs within the last ten years. Methodology: Five participatory design projects across different industries were systematically analyzed and compared in order to develop a framework...

  2. The SOAR Telescope Project Southern Observatory for Astronomical Research (SOAR)

    Science.gov (United States)

    2003-03-21

    completed SOAR dome and facility. 2. Dome The preliminary design of the dome was handled by M3 (US). A Brazilian firm, Equatorial Sistemas led the...for the Gemini Telescope during construction, now Project Manager at the National Solar Observatory • Robert Shelton, Provost of the University on

  3. Spatial conditions - the 3. supervisor in project organized teaching?

    DEFF Research Database (Denmark)

    Bering Keiding, Tina

    through reflection of its own border: is this new issue inside or outside the project. Individual rooms make it easier for the project to stabilize around its eigenvalues, but also enhance the risk of cognitive jog-trot. The challenge in this case becomes to seek out disturbances which can initiate new......The contribution presents a pilot study on project work situated in different spatial contexts. The main question for the study is if and how spatial conditions influence the interaction within and between projects. Possible answers to the question are sought through observations, informal...... interviews and questionnaires. The empirical findings are reflected in a Luhmann-based re-description of project organized group based teaching (Keiding 2008). Preliminary conclusions indicate that one big difference between open-space studio and individual group rooms is related to the immediate public...

  4. Preliminary evaluation of the physical impacts of a nearshore sand extraction project

    International Nuclear Information System (INIS)

    Anctil, F.; Ouellet, Y.

    1991-01-01

    A review is presented of the potential physical impacts of a nearshore sand extraction project in the Gulf of St. Lawrence. In Canada, sand extraction is mainly limited to the Beaufort Sea area, where in 1982 alone 15 million tonnes of aggregate was dredged to satisfy the requirements of offshore petroleum exploration; but there is much experience in nearshore dredging in Europe. Criteria related to impacts, developed for conditions prevailing in the North Sea (England) and the Gulf of Gascogne (France) are adapted to meet the more moderate hydrodynamic impacts of an extraction project in the Gulf of St. Lawrence. Potential impacts of extraction projects include destruction of sand bars or dunes, direct erosion resulting from beach drawdown or sedimentation interference, and impacts on littoral drift due to modified wave refraction patterns. Three schemes for the sand extraction are considered, and from the results, a fourth scheme is elaborated in such a way as to limit the negative impacts to the minor category. 17 refs., 5 figs., 4 tabs

  5. Astronomy Legacy Project - Pisgah Astronomical Research Institute

    Science.gov (United States)

    Barker, Thurburn; Castelaz, Michael W.; Rottler, Lee; Cline, J. Donald

    2016-01-01

    Pisgah Astronomical Research Institute (PARI) is a not-for-profit public foundation in North Carolina dedicated to providing hands-on educational and research opportunities for a broad cross-section of users in science, technology, engineering and math (STEM) disciplines. In November 2007 a Workshop on a National Plan for Preserving Astronomical Photographic Data (2009ASPC,410,33O, Osborn, W. & Robbins, L) was held at PARI. The result was the establishment of the Astronomical Photographic Data Archive (APDA) at PARI. In late 2013 PARI began ALP (Astronomy Legacy Project). ALP's purpose is to digitize an extensive set of twentieth century photographic astronomical data housed in APDA. Because of the wide range of types of plates, plate dimensions and emulsions found among the 40+ collections, plate digitization will require a versatile set of scanners and digitizing instruments. Internet crowdfunding was used to assist in the purchase of additional digitization equipment that were described at AstroPlate2014 Plate Preservation Workshop (www.astroplate.cz) held in Prague, CZ, March, 2014. Equipment purchased included an Epson Expression 11000XL scanner and two Nikon D800E cameras. These digital instruments will compliment a STScI GAMMA scanner now located in APDA. GAMMA will be adapted to use an electroluminescence light source and a digital camera with a telecentric lens to achieve high-speed high-resolution scanning. The 1μm precision XY stage of GAMMA will allow very precise positioning of the plate stage. Multiple overlapping CCD images of small sections of each plate, tiles, will be combined using a photo-mosaic process similar to one used in Harvard's DASCH project. Implementation of a software pipeline for the creation of a SQL database containing plate images and metadata will be based upon APPLAUSE as described by Tuvikene at AstroPlate2014 (www.astroplate.cz/programs/).

  6. Informatics in radiology: web-based preliminary reporting system for radiology residents with PACS integration.

    Science.gov (United States)

    O'Connell, Timothy; Chang, Debra

    2012-01-01

    While on call, radiology residents review imaging studies and issue preliminary reports to referring clinicians. In the absence of an integrated reporting system at the training sites of the authors' institution, residents were typing and faxing preliminary reports. To partially automate the on-call resident workflow, a Web-based system for resident reporting was developed by using the free open-source xAMP Web application framework and an open-source DICOM (Digital Imaging and Communications in Medicine) software toolkit, with the goals of reducing errors and lowering barriers to education. This reporting system integrates with the picture archiving and communication system to display a worklist of studies. Patient data are automatically entered in the preliminary report to prevent identification errors and simplify the report creation process. When the final report for a resident's on-call study is available, the reporting system queries the report broker for the final report, and then displays the preliminary report side by side with the final report, thus simplifying the review process and encouraging review of all of the resident's reports. The xAMP Web application framework should be considered for development of radiology department informatics projects owing to its zero cost, minimal hardware requirements, ease of programming, and large support community.

  7. Technical project for a new water purification solution

    Directory of Open Access Journals (Sweden)

    Toma Adina

    2018-01-01

    Full Text Available This research is part of the RO-BG Cross-Border Cooperation Program, project “CLEANDANUBE”, MIS-ETC 653, which has finalised by providing a common strategy to prevent the Danube’s pollution technological risks with oil and oil products. This paper presents a new sustainable water purification solution. A short introduction will be offered and an overview regarding the research and new methods to greening the waste is provided. The theoretical aspects of the centrifugal separation phenomenon are studied and the preliminary project bases were established. The paper conveys the possible constructive variations and the technological implications of those. Ultimately, the technical project for a new water purification solution and conclusions with critical points encountered during the designing phase are presented.

  8. 77 FR 9230 - Lock+ Hydro Friends Fund XLVII; FFP Project 52, LLC; Notice Announcing Preliminary Permit Drawing

    Science.gov (United States)

    2012-02-16

    ... Drawing The Commission has received two preliminary permit applications deemed filed on May 3, 2011, at 8... Secretary of the Commission, or her designee, will conduct a random drawing to determine the filing priority... applications as provided in section 4.37 of its regulations.\\2\\ The priority established by this drawing will...

  9. 77 FR 9232 - Lock+ Hydro Friends Fund XXXIV; FFP Project 58, LLC; Notice Announcing Preliminary Permit Drawing

    Science.gov (United States)

    2012-02-16

    ... Drawing The Commission has received two preliminary permit applications deemed filed on May 3, 2011, at 8... Secretary of the Commission, or her designee, will conduct a random drawing to determine the filing priority... applications as provided in section 4.37 of its regulations.\\2\\ The priority established by this drawing will...

  10. 77 FR 9915 - Lock+ Hydro Friends Fund XLIV; FFP Project 51, LLC; Notice Announcing Preliminary Permit Drawing

    Science.gov (United States)

    2012-02-21

    ... Drawing The Commission has received two preliminary permit applications deemed filed on May 3, 2011, at 8... of the Commission, or her designee, will conduct a random drawing to determine the filing priority of... applications as provided in section 4.37 of its regulations.\\2\\ The priority established by this drawing will...

  11. 77 FR 12281 - Lock+ Hydro Friends Fund IV; FFP Project 55, LLC; Notice Announcing Preliminary Permit Drawing

    Science.gov (United States)

    2012-02-29

    ... Drawing The Commission has received two preliminary permit applications deemed filed on May 3, 2011, at 8... Secretary of the Commission, or her designee, will conduct a random drawing to determine the filing priority... applications as provided in section 4.37 of its regulations.\\3\\ The priority established by this drawing will...

  12. 77 FR 9232 - Lock+ Hydro Friends Fund XXXV; FFP Project 57, LLC; Notice Announcing Preliminary Permit Drawing

    Science.gov (United States)

    2012-02-16

    ... Drawing The Commission has received two preliminary permit applications deemed filed on May 3, 2011, at 8... of the Commission, or her designee, will conduct a random drawing to determine the filing priority of... applications as provided in section 4.37 of its regulations.\\2\\ The priority established by this drawing will...

  13. EGNOS Monitoring Prepared in Space Research Centre P.A.S. for SPMS Project

    Science.gov (United States)

    Swiatek, Anna; Jaworski, Leszek; Tomasik, Lukasz

    2017-12-01

    The European Geostationary Overlay Service (EGNOS) augments Global Positioning System (GPS) by providing correction data and integrity information for improving positioning over Europe. EGNOS Service Performance Monitoring Support (SPMS) project has assumed establishment, maintenance and implementation of an EGNOS performance monitoring network. The paper presents preliminary results of analyses prepared in Space Research Centre, Polish Academy of Sciences (Warsaw), as one of partners in SPMS project.

  14. Preliminary Results on Uncertainty Quantification for Pattern Analytics

    Energy Technology Data Exchange (ETDEWEB)

    Stracuzzi, David John [Sandia National Laboratories (SNL-NM), Albuquerque, NM (United States); Brost, Randolph [Sandia National Laboratories (SNL-NM), Albuquerque, NM (United States); Chen, Maximillian Gene [Sandia National Laboratories (SNL-NM), Albuquerque, NM (United States); Malinas, Rebecca [Sandia National Laboratories (SNL-NM), Albuquerque, NM (United States); Peterson, Matthew Gregor [Sandia National Laboratories (SNL-NM), Albuquerque, NM (United States); Phillips, Cynthia A. [Sandia National Laboratories (SNL-NM), Albuquerque, NM (United States); Robinson, David G. [Sandia National Laboratories (SNL-NM), Albuquerque, NM (United States); Woodbridge, Diane [Sandia National Laboratories (SNL-NM), Albuquerque, NM (United States)

    2015-09-01

    This report summarizes preliminary research into uncertainty quantification for pattern ana- lytics within the context of the Pattern Analytics to Support High-Performance Exploitation and Reasoning (PANTHER) project. The primary focus of PANTHER was to make large quantities of remote sensing data searchable by analysts. The work described in this re- port adds nuance to both the initial data preparation steps and the search process. Search queries are transformed from does the specified pattern exist in the data? to how certain is the system that the returned results match the query? We show example results for both data processing and search, and discuss a number of possible improvements for each.

  15. Oxygen Consumption of Tilapia and Preliminary Mass Flows through a Prototype Closed Aquaculture System

    Science.gov (United States)

    Muller, Matthew S.; Bauer, Clarence F.

    1994-01-01

    Performance of NASA's prototype CELSS Breadboard Project Closed Aquaculture System was evaluated by estimating gas exchange quantification and preliminary carbon and nitrogen balances. The total system oxygen consumption rate was 535 mg/hr kg/fish (cv = 30%) when stocked with Tilapia aurea populations (fresh weights of 97 +/- 19 to 147 +/- 36 g/fish for various trials). Oxygen consumption by T. aurea (260 mg/hr kg/fish) contributed to approximately one-half of total system demand. Continuous carbon dioxide quantification methods were analyzed using the,relation of carbon dioxide to oxygen consumption. Overall food conversion rates averaged 18.2 +/- 3.2%. Major pathways for nitrogen and carbon in the system were described with preliminary mass closure of 60-80% and 60% for nitrogen and carbon.

  16. Preliminary seismicity and focal mechanisms for the southern Great Basin of Nevada and California: January 1992 through September 1992

    International Nuclear Information System (INIS)

    Harmsen, S.C.

    1994-01-01

    The telemetered southern Great Basin seismic network (SGBSN) is operated for the Department of Energy's Yucca Mountain Project (YMP). The US Geological Survey, Branch of Earthquake and Landslide Hazards, maintained this network until September 30, 1992, at which time all operational and analysis responsibilities were transferred to the University of Nevada at Reno Seismological Laboratory (UNRSL). This report contains preliminary earthquake and chemical explosion hypocenter listings and preliminary earthquake focal mechanism solutions for USGS/SGBSN data for the period January 1, 1992 through September 30, 1992, 15:00 UTC

  17. Student Attitudes Towards and Impressions of Project Citizen

    Directory of Open Access Journals (Sweden)

    Sara Winstead FRY

    2013-05-01

    Full Text Available Project Citizen is a civic education curriculum used across the United States and internationally, yet research about its impact on students is lacking in the literature. This article reports the results of a preliminary study designed to answer the following questions: What are students’ attitudes toward and perceptions of Project Citizen? How do their attitudes and perceptions compare to those of students who completed senior projects? Tenhigh school students and 23 first-year college students completed a questionnaire designed for this study. Our findings indicate that the high school students had positive perceptions of Project Citizen, and they self-reported anunderstanding and high levels of efficacy regarding civic responsibility. In contrast, the first-year college students had lower levels of efficacy regarding civic responsibility. Our findings suggest the importance of specific learning experiences to help students develop civic knowledge, skills, and dispositions, and indicate the need for further research into civic programs such as Project Citizen

  18. Advanced Engineering Environment FY09/10 pilot project.

    Energy Technology Data Exchange (ETDEWEB)

    Lamph, Jane Ann; Kiba, Grant W.; Pomplun, Alan R.; Dutra, Edward G.; Sego, Abraham L.

    2010-06-01

    The Advanced Engineering Environment (AEE) project identifies emerging engineering environment tools and assesses their value to Sandia National Laboratories and our partners in the Nuclear Security Enterprise (NSE) by testing them in our design environment. This project accomplished several pilot activities, including: the preliminary definition of an engineering bill of materials (BOM) based product structure in the Windchill PDMLink 9.0 application; an evaluation of Mentor Graphics Data Management System (DMS) application for electrical computer-aided design (ECAD) library administration; and implementation and documentation of a Windchill 9.1 application upgrade. The project also supported the migration of legacy data from existing corporate product lifecycle management systems into new classified and unclassified Windchill PDMLink 9.0 systems. The project included two infrastructure modernization efforts: the replacement of two aging AEE development servers for reliable platforms for ongoing AEE project work; and the replacement of four critical application and license servers that support design and engineering work at the Sandia National Laboratories/California site.

  19. Work plan for the Hanford Environmental Dose Reconstruction Project

    Energy Technology Data Exchange (ETDEWEB)

    1989-12-01

    The primary objective of the Hanford Environmental Dose Reconstruction (HEDR) Project is to estimate the radiation doses that populations could have received from nuclear operations at the Hanford Site since 1944, with descriptions of uncertainties inherent in such estimates. The secondary objective is to make project records--information that HEDR staff members used to estimate radiation doses--available to the public. Preliminary dose estimates for a limited geographic area and time period, certain radionuclides, and certain populations are planned to be available in 1990; complete results are planned to be reported in 1993. Project reports and references used in the reports are available to the public in the DOE Public Reading Room in Richland, Washington. Project progress is documented in monthly reports, which are also available to the public in the DOE Public Reading Room.

  20. Deep Underground Science and Engineering Laboratory - Preliminary Design Report

    CERN Document Server

    Lesko, Kevin T; Alonso, Jose; Bauer, Paul; Chan, Yuen-Dat; Chinowsky, William; Dangermond, Steve; Detwiler, Jason A; De Vries, Syd; DiGennaro, Richard; Exter, Elizabeth; Fernandez, Felix B; Freer, Elizabeth L; Gilchriese, Murdock G D; Goldschmidt, Azriel; Grammann, Ben; Griffing, William; Harlan, Bill; Haxton, Wick C; Headley, Michael; Heise, Jaret; Hladysz, Zbigniew; Jacobs, Dianna; Johnson, Michael; Kadel, Richard; Kaufman, Robert; King, Greg; Lanou, Robert; Lemut, Alberto; Ligeti, Zoltan; Marks, Steve; Martin, Ryan D; Matthesen, John; Matthew, Brendan; Matthews, Warren; McConnell, Randall; McElroy, William; Meyer, Deborah; Norris, Margaret; Plate, David; Robinson, Kem E; Roggenthen, William; Salve, Rohit; Sayler, Ben; Scheetz, John; Tarpinian, Jim; Taylor, David; Vardiman, David; Wheeler, Ron; Willhite, Joshua; Yeck, James

    2011-01-01

    The DUSEL Project has produced the Preliminary Design of the Deep Underground Science and Engineering Laboratory (DUSEL) at the rehabilitated former Homestake mine in South Dakota. The Facility design calls for, on the surface, two new buildings - one a visitor and education center, the other an experiment assembly hall - and multiple repurposed existing buildings. To support underground research activities, the design includes two laboratory modules and additional spaces at a level 4,850 feet underground for physics, biology, engineering, and Earth science experiments. On the same level, the design includes a Department of Energy-shepherded Large Cavity supporting the Long Baseline Neutrino Experiment. At the 7,400-feet level, the design incorporates one laboratory module and additional spaces for physics and Earth science efforts. With input from some 25 science and engineering collaborations, the Project has designed critical experimental space and infrastructure needs, including space for a suite of multi...

  1. 76 FR 30936 - West Maui Pumped Storage Water Supply, LLC; Notice of Preliminary Permit Application Accepted for...

    Science.gov (United States)

    2011-05-27

    ... Storage Water Supply, LLC; Notice of Preliminary Permit Application Accepted for Filing and Soliciting...-acre reservoir; (4) a turnout to supply project effluent water to an existing irrigation system; (5) a...,000 megawatt-hours. Applicant Contact: Bart M. O'Keeffe, West Maui Pumped Storage Water Supply, LLC, P...

  2. Preliminary Study on the High Efficiency Supercritical Pressure Water-Cooled Reactor for Electricity Generation

    Energy Technology Data Exchange (ETDEWEB)

    Bae, Yoon Yeong; Park, Jong Kyun; Cho, Bong Hyun and others

    2006-01-15

    This research has been performed to introduce a concept of supercritical pressure water cooled reactor(SCWR) in Korea The area of research includes core conceptual design, evaluation of candidate fuel, fluid systems conceptual design with mechanical consideration, preparation of safety analysis code, and construction of supercritical pressure heat transfer test facility, SPHINX, and preliminary test. As a result of the research, a set of tools for the reactor core design has been developed and the conceptual core design with solid moderator was proposed. The direct thermodynamic cycle has been studied to find a optimum design. The safety analysis code has also been adapted to supercritical pressure condition. A supercritical pressure CO2 heat transfer test facility has been constructed and preliminary test proved the facility works as expected. The result of this project will be good basis for the participation in the international collaboration under GIF GEN-IV program and next 5-year mid and long term nuclear research program of MOST. The heat transfer test loop, SPHINX, completed as a result of this project may be used for the power cycle study as well as further heat transfer study for the various geometries.

  3. Synchrotron radiation sources and condensers for projection x-ray lithography

    International Nuclear Information System (INIS)

    Murphy, J.B.; MacDowell, A.A.; White, D.L.; Wood, O.R. II

    1992-01-01

    The design requirements for a compact electron storage ring that could be used as a soft x-ray source for projection lithography are discussed. The design concepts of the x-ray optics that are required to collect and condition the radiation in divergence, uniformity and direction to properly illuminate the mask and the particular x-ray projection camera used are discussed. Preliminary designs for an entire soft x-ray projection lithography system using an electron storage ring as a soft X-ray source are presented. It is shown that by combining the existing technology of storage rings with large collection angle condensers, a powerful and reliable source of 130 Angstrom photons for production line projection x-ray lithography is possible

  4. Integrated Project Control and Technical Support

    International Nuclear Information System (INIS)

    Kim, Jun Yeon; Kim, Jun Yeon; Joo, Po Kook and others

    2005-08-01

    First, Since PEFP puts it's aim on technology innovation through collaboration and technological fusion among the sub-projects from the various fields. It has been tried to make the sub-projects consist with the goal of the whole project through building and running the integrated project control system. Also, adopting CPM(Critical Process Management), intensive process management framework has been founded. Secondly, for the every procedure, including purchase, building, installation and a trial running, license, quality control, etc., could be efficiently executed, every related task has been carried out. And, the tasks involved in international cooperative relationship and host site selection are carried out as well, so that PEFP could be firmly supported. Finally, Strategic management procedures including TRM(Technology Road Map), economic evaluation on PEFP, preliminary evaluation on company-involved R and D and TRESIS(Technology, Resources, Economic Evaluation System) are made up not only for the purpose of managing efficiency and effectiveness on the investment, but also for the purpose of life cycle management from developing stage to commercializing stage

  5. Integrated Project Control and Technical Support

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Jun Yeon; Kim, Jun Yeon; Joo, Po Kook and others

    2005-08-15

    First, Since PEFP puts it's aim on technology innovation through collaboration and technological fusion among the sub-projects from the various fields. It has been tried to make the sub-projects consist with the goal of the whole project through building and running the integrated project control system. Also, adopting CPM(Critical Process Management), intensive process management framework has been founded. Secondly, for the every procedure, including purchase, building, installation and a trial running, license, quality control, etc., could be efficiently executed, every related task has been carried out. And, the tasks involved in international cooperative relationship and host site selection are carried out as well, so that PEFP could be firmly supported. Finally, Strategic management procedures including TRM(Technology Road Map), economic evaluation on PEFP, preliminary evaluation on company-involved R and D and TRESIS(Technology, Resources, Economic Evaluation System) are made up not only for the purpose of managing efficiency and effectiveness on the investment, but also for the purpose of life cycle management from developing stage to commercializing stage.

  6. Ocean thermal energy conversion (OTEC) power system development. Preliminary design report, Appendices, Part 1 (Final)

    Energy Technology Data Exchange (ETDEWEB)

    1978-12-04

    The objective of this project is the development of a preliminary design for a full-sized, closed cycle, ammonia power system module for the 100 MWe OTEC demonstration plant. In turn, this demonstration plant is to demonstrate, by 1984, the operation and performance of an Ocean Thermal Power Plant having sufficiently advanced heat exchanger design to project economic viability for commercial utilization in the late 1980's and beyond. Included in this power system development are the preliminary designs for a proof-of-concept pilot plant and test article heat exchangers which are scaled in such a manner as to support a logically sequential, relatively low-cost development of the full-scale power system module. The conceptual designs are presented for the demonstration plant power module, the proof-of-concept pilot plant, and for a pair of test article heat exchangers. Costs associated with the design, development, fabrication, checkout, delivery, installation, and operation are included. The accompanying design and producibilty studies on the full-scale power system module project the performance/economics for the commercial plant. This section of the report contains appendices on the developed computer models, water system dynamic studies, miscellaneous performance analysis, materials and processes, detailed equipment lists, turbine design studies, tube cleaner design, ammonia leak detection, and heat exchanger design supporting data. (WHK)

  7. Rock stress measurements. Preparatory stage of the equipment development project

    International Nuclear Information System (INIS)

    Mononen, S.; Hakala, M.; Mikkola, P.

    2002-01-01

    In recent years the rock stress measurement methods used in Finland have been overcoring and hydraulic fracturing. There have been mainly two companies involved in these measurements, namely Suomen Malmi Oy (Smoy) and SwedPower AB. Smoy has done measurements for mines and for rock engineering projects, whereas SwedPower AB has mainly been involved in nuclear waste disposal investigations and conducted hydraulic fracturing measurements in deep boreholes. Smoy together with its partners started in February 2001 a project named JTM, which was a preliminary stage for a future project, which aims to develop a device most suitable for rock stress measurements in Finland. The partners in the project were HUT Rock Engineering, Posiva Oy, Saanio and Riekkola Oy, Gridpoint Finland Oy and Geopros Oy. Tekes, the National Technology Agency, provided almost half of the project funding. In the management group of the project were Pekka Mikkola (chairman) and Tero Laurila from Smoy, Pekka Saerkkae and Sakari Mononen (full-time researcher) from HUT, Aimo Hautojaervi (Posiva Oy), Erik Johansson (Saanio and Riekkola Oy), Matti Hakala (Gridpoint Finland Oy) and Heikki Haemaelaeinen (Geopros Oy). The aim of the JTM-project was to find out the needs for the development of a device most suitable for rock stress measurements in Finnish mines and rock engineering projects. During the project work was done to find out the range of rock stress measurement devices available, to find out the needs for measurements, and to get acquainted to the measurements done in Scandinavia. Also a report of the most suitable methods for Finnish rock conditions was done based on literature and on interviews of rock stress experts. Based on all the information collected during the project a clear picture of the needs for rock stress measurements in Finland could be formed and a preliminary plan of a future project was done. The aim of the suggested project is to build a device based on hydraulic fracturing

  8. Preliminary detection of explosive standard components with Laser Raman Technique

    International Nuclear Information System (INIS)

    Botti, S.; Ciardi, R.

    2008-01-01

    Presently, our section is leader of the ISOTREX project (Integrated System for On-line TRace EXplosives detection in solid, liquid and vapour state), funded in the frame of the PASR 2006 action (Preparatory Action on the enhancement of the European industrial potential in the field of Security Research Preparatory Action) of the 6. EC framework. ISOTREX project will exploit the capabilities of different laser techniques as LIBS (Laser Induced Breakdown Spectroscopy), LPA (Laser Photo Acustic) and CRDS (Cavity Ring Down Spectroscopy) to monitor explosive traces. In this frame, we extended our investigation also to the laser induced Raman effect spectroscopy, in order to investigate its capabilities and possible future integration. We analysed explosive samples in bulk solid phase, diluted liquid phase and as evaporated films over suitable substrate. In the following, we present the main results obtained, outlining preliminary conclusions [it

  9. Project of compact accelerator for cancer proton therapy

    International Nuclear Information System (INIS)

    Picardi, L.; Ronsivalle, C.; Vignati, A.

    1995-04-01

    The status of the sub-projetc 'Compact Accelerator' in the framework of the Hadrontherapy Project leaded by Prof. Amaldi is described. Emphasis is given to the reasons of the use of protons for radiotherapy applications, to the results of the preliminary design studies of four types of accelerators as possible radiotherapy dedicated 'Compact Accelerator' and to the scenario of the fonts of financial resources

  10. 76 FR 28025 - East Maui Pumped Storage Water Supply LCC; Notice of Preliminary Permit Application Accepted for...

    Science.gov (United States)

    2011-05-13

    ... Storage Water Supply LCC; Notice of Preliminary Permit Application Accepted for Filing and Soliciting... Act (FPA), proposing to study the feasibility of the East Maui Pumped Storage Water Supply Project to.... Bart M. O'Keeffe, East Maui Pumped Storage Water Supply LLC; P.O. Box 1916; Discovery Bay, CA 94505...

  11. The Azimuth Project: an Open-Access Educational Resource

    Science.gov (United States)

    Baez, J. C.

    2012-12-01

    The Azimuth Project is an online collaboration of scientists, engineers and programmers who are volunteering their time to do something about a wide range of environmental problems. The project has several aspects: 1) a wiki designed to make reliable, sourced information easy to find and accessible to a technically literate nonexperts, 2) a blog featuring expository articles and news items, 3) a project to write programs that explain basic concepts of climate physics and illustrate principles of good open-source software design, and 4) a project to develop mathematical tools for studying complex networked systems. We discuss the progress so far and some preliminary lessons. For example, enlisting the help of experts outside academia highlights the problems with pay-walled journals and the benefits of open access, as well as differences between how software development is done commercially, in the free software community, and in academe.

  12. 77 FR 790 - Grant Lake Hydroelectric Project; Notice of Preliminary Permit Application Accepted for Filing...

    Science.gov (United States)

    2012-01-06

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Project No. 13212-002] Grant Lake.... The proposed project would consist of: (1) Either (a) a 2-foot-high by 120-foot-long, concrete gravity... project reservoir, with a total storage capacity of 15,900 acre-feet and a water surface area of 1,790...

  13. Small hydropower station in Lavin - Preliminary study

    International Nuclear Information System (INIS)

    Merz, F.

    2008-05-01

    This illustrated final report for the Swiss Federal Office of Energy (SFOE) presents the results of a preliminary study regarding a proposed small hydropower installation on the alpine river Lavinuoz in Lavin, Switzerland. The geographical situation with mountains and glaciers in the catchment area of the proposed hydropower installation is discussed as are the appropriate water catchment installations. Possible dangers caused by avalanches and rock fall are examined. The power to be produced - 5,500,000 kWh/y - by the turbine which is nominally rated at 1350 kW is discussed, as are estimates of production costs. Figures on the investments required and the economic feasibility of the project are discussed, as are environmental factors that are to be taken into account.

  14. Key concepts of the INCAS multicomputer project

    Energy Technology Data Exchange (ETDEWEB)

    Nehmer, J.; Haban, D.; Mattern, F.; Wybranietz, D.; Rombach, H.D.

    1987-08-01

    This paper gives an overview of the INCAS (INCremental Architecture for distributed Systems) multicomputer project, which aims at the development of a comprehensive methodology for the design and implementation of locally distributed systems. A structuring concept for distributed operating systems has been developed and integrated into the system implementation language LADY. The concurrent high-level programming language CSSA, based on the actor model, has been designed for the implementation of distributed applications. A substantial effort in the INCAS project is directed towards the development of a distributed test methodology. An experimental system has been implemented on a network of ten MC68000 microcomputers. Preliminary experience with the methodology has been gained from a small number of prototype applications.

  15. BIPS-FS preliminary design, miscellaneous notes

    International Nuclear Information System (INIS)

    1976-01-01

    A compendium of flight system preliminary design internal memos and progress report extracts for the Brayton Isotope Power System Preliminary Design Review to be held July 20, 21, and 22, 1975 is presented. The purpose is to bring together those published items which relate only to the preliminary design of the Flight System, Task 2 of Phase I. This preliminary design effort was required to ensure that the Ground Demonstration System will represent the Flight System as closely as possible

  16. BEHAVIOR OF SURFACTANT MIXTURE AT SOLID/LIQUID AND OIL/LIQUID INTERFACE IN CHEMICAL FLOODING SYSTEMS

    Energy Technology Data Exchange (ETDEWEB)

    Prof. P. Somasundaran

    2002-03-01

    The aim of the project is to develop and evaluate efficient novel surfactant mixtures for enhanced oil recovery. Preliminary ultra-filtration tests suggest that two kinds of micelles may exist in binary surfactant mixtures at different concentrations. Due to the important role played in interfacial processes by micelles as determined by their structures, focus of the current work is on the delineation of the relationship between such aggregate structures and chemical compositions of the surfactants. A novel analytical centrifuge application is explored to generate information on structures of different surfactants aggregates. In this report, optical systems, typical output of the analytical ultracentrifuge results and four basic experiments are discussed. Initial sedimentation velocity investigations were conducted using nonyl phenol ethoxylated decyl ether (NP-10) to choose the best analytical protocol, calculate the partial specific volume and obtain information on sedimentation coefficient, aggregation mass of micelles. The partial specific volume was calculated to be 0.920. Four softwares: Optima{trademark} XL-A/XL-I data analysis software, DCDT+, Svedberg and SEDFIT, were compared for the analysis of sedimentation velocity experimental data. The sedimentation coefficient and aggregation number of NP-10 micelles obtained using the first three softwares at 25 C are 209, 127, and 111, respectively. The last one is closest to the result from Light Scattering. The reason for the differences in numbers obtained using the three softwares is discussed. Based on these tests, Svedberg and SEDFIT analysis are chosen for further studies. This approach using the analytical ultracentrifugation offers an unprecedented opportunity now to obtain important information on mixed micelles and their role in interfacial processes.

  17. 45 CFR 150.217 - Preliminary determination.

    Science.gov (United States)

    2010-10-01

    ... 45 Public Welfare 1 2010-10-01 2010-10-01 false Preliminary determination. 150.217 Section 150.217... Are Failing To Substantially Enforce HIPAA Requirements § 150.217 Preliminary determination. If, at... designees). (b) Notifies the State of CMS's preliminary determination that the State has failed to...

  18. Preliminary fiscal evaluation of Alberta oil sands terms

    International Nuclear Information System (INIS)

    Van Meurs, P.

    2007-01-01

    The cost of oil sands projects varies significantly. While costs have escalated considerably over the past few years, oil prices have gone significantly higher. This report provided an economic evaluation of the current fiscal terms applicable to Alberta oil sands. The analysis was done to evaluate the profitability of oil sand projects to investors under current conditions based on the generic royalty regime based on bitumen values. The objective of the royalty review was to determine whether Albertans received a fair share from their oil and gas resources. It discussed the wide variety of oil sands projects in Alberta using five case studies as examples. Cases involving steam assisted gravity drainage (SAGD) operations were assessed for both the Athabasca Mine and Cold Lake. The report provided a discussion of the economic assumptions including economic cases as well as production, costs and price data. It then provided the preliminary results of the economic-fiscal evaluation from the investor perspective including profitability indicators; international comparisons; internal rate of return; and net present value. The government perspective was also discussed with reference to attractiveness indicators; royalties as a percentage of bitumen values; and non-discounted and discounted government take. A royalty and tax feature analysis was also provided. Several issues for possible further review were also presented. tabs

  19. Preliminary Hazards Analysis Plasma Hearth Process

    International Nuclear Information System (INIS)

    Aycock, M.; Coordes, D.; Russell, J.; TenBrook, W.; Yimbo, P.

    1993-11-01

    This Preliminary Hazards Analysis (PHA) for the Plasma Hearth Process (PHP) follows the requirements of United States Department of Energy (DOE) Order 5480.23 (DOE, 1992a), DOE Order 5480.21 (DOE, 1991d), DOE Order 5480.22 (DOE, 1992c), DOE Order 5481.1B (DOE, 1986), and the guidance provided in DOE Standards DOE-STD-1027-92 (DOE, 1992b). Consideration is given to ft proposed regulations published as 10 CFR 830 (DOE, 1993) and DOE Safety Guide SG 830.110 (DOE, 1992b). The purpose of performing a PRA is to establish an initial hazard categorization for a DOE nuclear facility and to identify those processes and structures which may have an impact on or be important to safety. The PHA is typically performed during and provides input to project conceptual design. The PRA then is followed by a Preliminary Safety Analysis Report (PSAR) performed during Title I and II design. This PSAR then leads to performance of the Final Safety Analysis Report performed during construction, testing, and acceptance and completed before routine operation. Radiological assessments indicate that a PHP facility, depending on the radioactive material inventory, may be an exempt, Category 3, or Category 2 facility. The calculated impacts would result in no significant impact to offsite personnel or the environment. Hazardous material assessments indicate that a PHP facility will be a Low Hazard facility having no significant impacts either onsite or offsite to personnel and the environment

  20. Project W-314 phase I environmental permits and approvals plan

    International Nuclear Information System (INIS)

    TOLLEFSON, K.S.

    1999-01-01

    This document describes the range of environmental actions, including required permits and other agency approvals, for Project W-314 activities in the Hanford Site's Tank Waste Remediation System. This document outlines alternative approaches to satisfying applicable environmental standards, and describes selected strategies for acquiring permits and other approvals needed for waste feed delivery to proceed. This document also includes estimated costs and schedule to obtain the required permits and approvals based on the selected strategy. It also provides estimated costs for environmental support during design and construction based on the preliminary project schedule provided

  1. Statistical Analysis of the Skaion Network Security Dataset

    Science.gov (United States)

    2012-09-01

    DataType :=xlDelimited, _ TextQualifier:=xlDoubleQuote, ConsecutiveDelimiter:=True, Tab:=False, _ Semicolon:=False, Comma:=False, Space...Selection.TextToColumns Destination:=Range(“E1”), DataType :=xlDelimited, _ TextQualifier:=xlDoubleQuote, ConsecutiveDelimiter:=True, Tab:=False...True Columns(“F:F”).Select Selection.TextToColumns Destination:=Range(“F1”), DataType :=xlDelimited, _ TextQualifier:=xlDoubleQuote

  2. Learning Word Subsumption Projections for the Russian Language

    Directory of Open Access Journals (Sweden)

    Ustalov Dmitry

    2016-01-01

    Full Text Available The semantic relations of hypernymy and hyponymy are widely used in various natural language processing tasks for modelling the subsumptions in common sense reasoning. Since the popularisation of the distributional semantics, a significant attention is paid to applying word embeddings for inducing the relations between words. In this paper, we show our preliminary results on adopting the projection learning technique for computing hypernyms from hyponyms using word embeddings. We also conduct a series of experiments on the Russian language and release the open source software for learning hyponym-hypernym projections using both CPUs and GPUs, implemented with the TensorFlow machine learning framework.

  3. A collaborative archaeological research and conservation project for Moriori carved trees (rakau momori), Rekohu (Chatham Island)

    International Nuclear Information System (INIS)

    Barber, I.; Maxwell, J.

    2011-01-01

    In January-February 2010 a conservation and site-recording project began on Rekohu (Chatham Island) to locate, assess and digitally scan archaeological carved trees known as rakau momori ('dendroglyphs'). This paper briefly considers earlier work on carved trees before reporting preliminary and anticipated outcomes from our recent collaborative rakau momori archaeological project. 14 refs., 9 figs., 2 tabs.

  4. Application of the ALARP principle to a major refurbishment project at Sellafield

    International Nuclear Information System (INIS)

    Hendrickson, W.R.; Coates, R.

    1989-01-01

    A formalised structured approach to the ALARP principle has been developed and is being applied to occupational radiation exposure on a major refurbishment project at Sellafield. The processes consider the conceptual and subsequent detailed design stages, planning and operational control and incorporates a dose feedback and review system. The approach has led to significant dose savings so far on the project, with recorded doses being significantly less than the doses estimated at the preliminary assessment stage. (author)

  5. Transport project evaluation: feasibility risk assessment and scenario forecasting

    DEFF Research Database (Denmark)

    Salling, Kim Bang; Leleur, Steen

    2017-01-01

    This paper presents a new approach to transport project assessment in terms of feasibility risk assessment and reference class forecasting. Conventionally, transport project assessment is based upon a Cost-Benefit Analysis (CBA) where evaluation criteria such as Benefit Cost Ratios (BCR...... on the preliminary construction cost estimates. Hereafter, a quantitative risk analysis is provided making use of Monte Carlo simulation. This approach facilitates random input parameters based upon reference class forecasting, hence, a parameter data fit has been performed in order to obtain validated probability...... Scenario Forecasting (RSF) frame. The RSF is anchored in the cost-benefit analysis; thus, it provides decision-makers with a quantitative mean of assessing the transport infrastructure project. First, the RSF method introduces uncertainties within the CBA by applying Optimism Bias uplifts...

  6. Comparison of three methods of tonometry in normal subjects: Goldmann applanation tonometer, non-contact airpuff tonometer, and Tono-Pen XL.

    Science.gov (United States)

    Yilmaz, Ihsan; Altan, Cigdem; Aygit, Ebru Demet; Alagoz, Cengiz; Baz, Okkes; Ahmet, Sibel; Urvasizoglu, Semih; Yasa, Dilek; Demirok, Ahmet

    2014-01-01

    WE AIMED TO COMPARE INTRAOCULAR PRESSURE (IOP) MEASUREMENTS VIA THREE DIFFERENT TONOMETERS: the Goldmann applanation tonometer (GAT), the Tono-Pen(®) XL (TPXL), and a non-contact airpuff tonometer (NCT). This was a cross-sectional study of 200 eyes from 200 patients. Right eyes of all patients were included in this study. IOP was measured via GAT, NCT, and TPXL by three physicians. Each physician used one of the tonometers. Measurements via the three devices were compared. The mean IOP was 15.5±2.2 mmHg (range 10-22) with the GAT, 16.1±3.0 (range 9-25) with the TPXL, and 16.1±2.8 (range 10-26) with the NCT. Bland-Altman analysis showed that the mean difference between measurements from the NCT and the GAT was 0.6±2.3 mmHg. The mean difference between the TPXL and GAT measurements was 0.7±2.5 mmHg. The mean difference between the NCT and TPXL measurements was -0.02±3.0 mmHg. There was no significant difference between the groups according to a one-way analysis of variance (ANOVA) test. P-values were 0.998 for NCT-TPXL, 0.067 for NCT-GAT, and 0.059 for TPXL-GAT. The NCT and TPXL provide IOP measurements comparable to those of the gold standard GAT in normotensive eyes.

  7. The HCV Synthesis Project: Scope, methodology, and preliminary results

    Directory of Open Access Journals (Sweden)

    Scheinmann Roberta

    2008-09-01

    Full Text Available Abstract Background The hepatitis C virus (HCV is hyper-endemic in injecting drug users. There is also excess HCV among non-injection drug users who smoke, snort, or sniff heroin, cocaine, crack, or methamphetamine. Methods To summarize the research literature on HCV in drug users and identify gaps in knowledge, we conducted a synthesis of the relevant research carried out between 1989 and 2006. Using rigorous search methods, we identified and extracted data from published and unpublished reports of HCV among drug users. We designed a quality assurance system to ensure accuracy and consistency in all phases of the project. We also created a set of items to assess study design quality in each of the reports we included. Results We identified 629 reports containing HCV prevalence rates, incidence rates and/or genotype distribution among injecting or non-injecting drug user populations published between January 1989 and December 2006. The majority of reports were from Western Europe (41%, North America (26%, Asia (11% and Australia/New Zealand (10%. We also identified reports from Eastern Europe, South America, the Middle East, and the Caribbean. The number of publications reporting HCV rates in drug users increased dramatically between 1989 and 2006 to 27–52 reports per year after 1998. Conclusion The data collection and quality assurance phases of the HCV Synthesis Project have been completed. Recommendations for future research on HCV in drug users have come out of our data collection phase. Future research reports can enhance their contributions to our understanding of HCV etiology by clearly defining their drug user participants with respect to type of drug and route of administration. Further, the use of standard reporting methods for risk factors would enable data to be combined across a larger set of studies; this is especially important for HCV seroconversion studies which suffer from small sample sizes and low power to examine risk

  8. Exploratory shaft facility preliminary designs - Permian Basin

    International Nuclear Information System (INIS)

    1983-09-01

    The purpose of the Preliminary Design Report, Permian Basin, is to provide a description of the preliminary design for an Exploratory Shaft Facility in the Permian Basin, Texas. This issue of the report describes the preliminary design for constructing the exploratory shaft using the Large Hole Drilling method of construction and outlines the preliminary design and estimates of probable construction cost. The Preliminary Design Report is prepared to complement and summarize other documents that comprise the design at the preliminary stage of completion, December 1982. Other design documents include drawings, cost estimates and schedules. The preliminary design drawing package, which includes the construction schedule drawing, depicts the descriptions in this report. For reference, a list of the drawing titles and corresponding numbers are included in the Appendix. The report is divided into three principal sections: Design Basis, Facility Description, and Construction Cost Estimate. 30 references, 13 tables

  9. Cost benchmarking of railway projects in Europe – can it help to reduce costs?

    DEFF Research Database (Denmark)

    Trabo, Inara; Landex, Alex; Nielsen, Otto Anker

    a certain overview of the range of costs in various budget disciplines. The Copenhagen-Ringsted project is shown to be right in the middle of the range in terms of total costs per kilometre, and its values in the discipline comparisons do not significantly differ from the values of the less expensive...... projects. Deeper analysis of project unit costs is still continuing, but the preliminary results show that the cost values for projects located in the same geographical zone are similar. For example, this can be explained by their use of the same construction companies. However, unit prices in southern...

  10. Hydrological and geological preliminary studies in the scope of the RMB project

    International Nuclear Information System (INIS)

    Ferreira, Vinicius V.M.; Barreto, Alberto A.; Aleixo, Bruna L.

    2011-01-01

    The RMB - Brazilian Multipurpose Reactor is a project that will contribute decisively in order to develop the science and the technology of the country. However, the licensing process of this facility is not a simple task, since it involves nuclear and environmental questions. The utilization of geoprocessing tools became in the last years an important technique to aid the development of several studies, and will be necessary also in this project. The objective of this work is to present the first hydrological and geological geoprocessing studies done in order to support the future environmental licensing process of the facility. The results show that further efforts should be done since there is a lack of many data needed for the next steps. (author)

  11. Preliminary draft: environmental impact statement for Hot Engineering Test Project at Oak Ridge National Laboratory

    International Nuclear Information System (INIS)

    Boyle, J.W.; Baxter, B.J.; Carpenter, J.A.

    1978-08-01

    The project considered is the Hot Engineering Test Project (HETP), which is to be located in largely existing facilities at Oak Ridge National Laboratory (ORNL). The project is a part of the National High Temperature Gas-Cooled Reactor Fuel Recycle Program, which seeks to demonstrate the technological feasibility of the recycle processes. The HETP will attempt to confirm the operability of the processes (proven feasible in cold or nonradioactive, benchtop experimentation) under the more realistic radioactive condition. As such, the operation will involve the reprocessing and refabrication of spent HTGR fuel rods obtained from the Fort St. Vrain reactor. The reference fuel is highly enriched uranium. No significant radiological impacts are expected from routine operation of the facility to any biota or ecosystem. Concentrations of one or more radionuclides in Whiteoak Lake will increase as a result of the combination of HETP wastes with other ORNL wastes. Nonradiological effects from construction activities and routine operation should be insignificant on land and water use and on terrestrial and aquatic ecosystems. No significant socioeconomic impacts should occur from either construction or operation of the facility. Some conservative accident scenarios depict significant releases of radioactivity. Effects should be localized and would not be severe for all but the most unlikely of such incidents. No significant long-term commitment of resources is expected to be required for the project. Nor are any large quantities of scarce or critical resources likely to be irreversibly or irretrievably committed to the project. Principal alternatives considered were: relocation of the project site, postponement of the project schedule, project cancellation, and chemical process variations

  12. Process, cost modeling and simulations for integrated project development of biomass for fuel and protein

    International Nuclear Information System (INIS)

    Pannir Selvam, P.V.; Wolff, D.M.B.; Souza Melo, H.N.

    1998-01-01

    The construction of the models for biomass project development are described. These models, first constructed using QPRO electronic spread sheet for Windows, are now being developed with the aid of visual and object oriented program as tools using DELPHI V.1 for windows and process simulator SUPERPRO, V.2.7 Intelligent Inc. These models render the process development problems with economic objectives to be solved very rapidly. The preliminary analysis of cost and investments of biomass utilisation projects which are included for this study are: steam, ammonia, carbon dioxide and alkali pretreatment process, methane gas production using anaerobic digestion process, aerobic composting, ethanol fermentation and distillation, effluent treatments using high rate algae production as well as cogeneration of energy for drying. The main project under developments are the biomass valuation projects with the elephant (Napier) grass, sugar cane bagasse and microalgae, using models for mass balance, equipment and production cost. The sensibility analyses are carried out to account for stochastic variation of the process yield, production volume, price variations, using Monte Carlo method. These models allow the identification of economical and scale up problems of the technology. The results obtained with few preliminary project development with few case studies are reported for integrated project development for fuel and protein using process and cost simulation models. (author)

  13. Conceptual design statement of work for the immobilized low-activity waste disposal facility, project W-520

    International Nuclear Information System (INIS)

    Pickett, W.W.

    1998-01-01

    This Statement of Work outlines the deliverables and schedule for preparation of the Project W-520 Conceptual Design Report, including, work plans, site development plan, preliminary safety evaluation, and conceptual design

  14. MEGAPIE-TEST: A European Project on Spallation Target Testing

    International Nuclear Information System (INIS)

    Knebel, Joachim U.; Klein, Jean-Christophe; Gorse, Dominique; Agostini, Pietro; Groeschel, Friedrich; Kupschus, Peter; Kirchner, Thomas; Vogt, Jean-Bernard

    2002-01-01

    Within the Euratom 5. Framework Programme (5FP) the European Commission is funding the MEGAPIE-TEST Project (Megawatt Pilot Experiment - Testing) over a period of three years, starting in September 2001. The project is combining the efforts of 8 main associations. MEGAPIE is a liquid metal spallation target of 1 MW of beam power. The main results of the MEGAPIE-TEST project will be: Development and comprehensive testing of a liquid metal spallation target both under beam-off and beam-on conditions, and the set up of a handbook on the design of a neutron spallation source in general. The operation of MEGAPIE within the accelerator complex SINQ at Paul Scherrer Institute (PSI), Switzerland, is envisaged in 2004. MEGAPIE is a first decisive step to realize a liquid metal spallation target in Europe. This report is giving an overview of the MEGAPIE-TEST Project, the overall work plan, and preliminary results from the design support and validation, which form an important basis for the project. (authors)

  15. Reproduction of the Yucca Mountain Project TSPA-LA Uncertainty and Sensitivity Analyses and Preliminary Upgrade of Models

    Energy Technology Data Exchange (ETDEWEB)

    Hadgu, Teklu [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States). Nuclear Waste Disposal Research and Analysis; Appel, Gordon John [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States). Nuclear Waste Disposal Research and Analysis

    2016-09-01

    Sandia National Laboratories (SNL) continued evaluation of total system performance assessment (TSPA) computing systems for the previously considered Yucca Mountain Project (YMP). This was done to maintain the operational readiness of the computing infrastructure (computer hardware and software) and knowledge capability for total system performance assessment (TSPA) type analysis, as directed by the National Nuclear Security Administration (NNSA), DOE 2010. This work is a continuation of the ongoing readiness evaluation reported in Lee and Hadgu (2014) and Hadgu et al. (2015). The TSPA computing hardware (CL2014) and storage system described in Hadgu et al. (2015) were used for the current analysis. One floating license of GoldSim with Versions 9.60.300, 10.5 and 11.1.6 was installed on the cluster head node, and its distributed processing capability was mapped on the cluster processors. Other supporting software were tested and installed to support the TSPA-type analysis on the server cluster. The current tasks included verification of the TSPA-LA uncertainty and sensitivity analyses, and preliminary upgrade of the TSPA-LA from Version 9.60.300 to the latest version 11.1. All the TSPA-LA uncertainty and sensitivity analyses modeling cases were successfully tested and verified for the model reproducibility on the upgraded 2014 server cluster (CL2014). The uncertainty and sensitivity analyses used TSPA-LA modeling cases output generated in FY15 based on GoldSim Version 9.60.300 documented in Hadgu et al. (2015). The model upgrade task successfully converted the Nominal Modeling case to GoldSim Version 11.1. Upgrade of the remaining of the modeling cases and distributed processing tasks will continue. The 2014 server cluster and supporting software systems are fully operational to support TSPA-LA type analysis.

  16. Project Execution Plan for Project W-211 Initial Tank Retrieval Systems (ITRS)

    International Nuclear Information System (INIS)

    VAN BEEK, J.E.

    2000-01-01

    This Project Execution Plan documents the methodology for managing Project W-211. Project W-211, Initial Tank Retrieval Systems (ITRS), is a fiscal year 1994 Major Systems Acquisition that will provide systems for retrieval of radioactive wastes from selected double-shell tanks (DST). The contents of these tanks are a combination of supernatant liquids and settled solids. To retrieve waste from the tanks, it is first necessary to mix the liquid and solids prior to transferring the slurry to alternative storage or treatment facilities. The ITRS will provide systems to mobilize the settled solids and transfer the wastes out of the tanks. In so doing, ITRS provides feed for the future waste treatment plant, allows for consolidation of tank solids to manage space within existing DST storage capacity, and supports continued safe storage of tank waste. The ITRS scope has been revised to include waste retrieval systems for tanks AP-102, AP-104, AN-102, AN-103, AN-104, AN-105, AY-102, AZ-102, and SY-102. This current tank selection and sequence provides retrieval systems supporting the River Protection Project (RF'P) Waste Treatment Facility and sustains the ability to provide final remediation of several watch list DSTs via treatment. The ITRS is configured to support changing program needs, as constrained by available budget, by maintaining the flexibility for exchanging tanks requiring mixer pump-based retrieval systems and shifting the retrieval sequence. Preliminary design was configured such that an adequate basis exists for initiating Title II design of a mixer pump-based retrieval system for any DST. This Project Execution Plan (PEP), derived from the predecessor Project Management Plan, documents the methodology for managing the ITRS, formalizes organizational responsibilities and interfaces, and identifies project requirements such as change control, design verification, systems engineering, and human factors engineering

  17. Quality Indicators in Laboratory Medicine: from theory to practice. Preliminary data from the IFCC Working Group Project "Laboratory Errors and Patient Safety".

    Science.gov (United States)

    Sciacovelli, Laura; O'Kane, Maurice; Skaik, Younis Abdelwahab; Caciagli, Patrizio; Pellegrini, Cristina; Da Rin, Giorgio; Ivanov, Agnes; Ghys, Timothy; Plebani, Mario

    2011-05-01

    The adoption of Quality Indicators (QIs) has prompted the development of tools to measure and evaluate the quality and effectiveness of laboratory testing, first in the hospital setting and subsequently in ambulatory and other care settings. While Laboratory Medicine has an important role in the delivery of high-quality care, no consensus exists as yet on the use of QIs focussing on all steps of the laboratory total testing process (TTP), and further research in this area is required. In order to reduce errors in laboratory testing, the IFCC Working Group on "Laboratory Errors and Patient Safety" (WG-LEPS) developed a series of Quality Indicators, specifically designed for clinical laboratories. In the first phase of the project, specific QIs for key processes of the TTP were identified, including all the pre-, intra- and post-analytic steps. The overall aim of the project is to create a common reporting system for clinical laboratories based on standardized data collection, and to define state-of-the-art and Quality Specifications (QSs) for each QI independent of: a) the size of organization and type of activities; b) the complexity of processes undertaken; and c) different degree of knowledge and ability of the staff. The aim of the present paper is to report the results collected from participating laboratories from February 2008 to December 2009 and to identify preliminary QSs. The results demonstrate that a Model of Quality Indicators managed as an External Quality Assurance Program can serve as a tool to monitor and control the pre-, intra- and post-analytical activities. It might also allow clinical laboratories to identify risks that lead to errors resulting in patient harm: identification and design of practices that eliminate medical errors; the sharing of information and education of clinical and laboratory teams on practices that reduce or prevent errors; the monitoring and evaluation of improvement activities.

  18. Lower Red River Meadow Stream Restoration Project

    International Nuclear Information System (INIS)

    1996-05-01

    As part of a continuing effort to restore anadromous fish populations in the South Fork Clearwater River basin of Idaho, Bonneville Power Administration (BPA) proposes to fund the Lower Red River Meadow Restoration Project (Project). The Project is a cooperative effort with the Idaho Soil and Water Conservation District, Nez Perce National Forest, Idaho Department of Fish and Game (IDFG), and the Nez Perce Tribe of Idaho. The proposed action would allow the sponsors to perform stream bank stabilization, aquatic and riparian habitat improvement activities on IDFG's Red River Management Area and to secure long-term conservation contracts or agreements for conducting streambank and habitat improvement activities with participating private landowners located in the Idaho County, Idaho, study area. This preliminary Environmental Assessment (EA) examines the potential environmental effects of stabilizing the stream channel, restoring juvenile fish rearing habitat and reestablishing a riparian shrub community along the stream

  19. A preliminary investigation on the effects of characteristics and contractual behaviour on civil engineering project performance

    Science.gov (United States)

    Ismail, W. N. W.; Adnan, H.; Yusuwan, N.; Maisham, M.; Hassan, A. A.

    2018-02-01

    The significant role of civil engineering project is not only to make the lives of people easier and secure but also to trigger the economic growth by providing infrastructure facilities as well as job opportunities. As it is dominantly initiated by government sectors, performance of the civil engineering projects is always observed. This study aims to investigate the characteristics of civil engineering project and the contractual behavior of the key participants and how do these two factors affect civil engineering projects performance. Literature reviews, content analysis and questionnaires survey were conducted to undertake the research. A total of 50 questionnaires were distributed and 10 questionnaires were returned, resulting in a 20% response rate. The research unveiled that performance of civil engineering projects are influenced greatly by the ability to handle the unpredictable character of the civil engineering projects and adequate behavioral management. Apart from that, balancing the factors with high quality of workmanship, avoidance or well managed conflicts and high satisfaction level will ensure performance in projects.

  20. Preliminary on-surface experiments for backfilling a HLW repository: the ESDRED project

    International Nuclear Information System (INIS)

    Bastiaens, W.

    2007-01-01

    ESDRED is a technological integrated project within the context of the Sixth Framework Program of EURATOM. The project aims to demonstrate the technical feasibility at an industrial scale of specific technologies related to the construction, operation and closure of a deep geological repository for spent fuel and long-lived radioactive waste. The Belgian design for high level waste disposal is based on the so-called Supercontainer concept. Within this concept, the waste is encased in a carbon steel overpack, which is consequently fitted into a 70 cm thick concrete shell, in its turn enveloped by a stainless steel liner. A Supercontainer measures about 2 m in diameter. In the design of the repository, the Supercontainers will be emplaced, one after the other, in disposal galleries. The space between the Supercontainers and the gallery lining needs to be filled up with a solid material. The most essential function of this component, referred to as backfill, is to prevent a collapse of the gallery. A secondary function is to limit the presence of free oxygen, to limit corrosion. In the ESDRED project EIG EURIDICE, together with SCK-CEN and ONDRAF/NIRAS, investigates technologies to apply the backfill. Two options to apply the backfill were investigated within the ESDRED project: fill the gap with a granular material and backfill the gap with a grout. The prime operational target will be to achieve a 100 percent filling of the gap. A wide variety of materials was tested. A number of considerations regarding long-term safety and operational feasibility impose constraints on the backfill component:it should preserve the corrosion-protective environment established by the Supercontainer; it should not act as a thermal isolator; it should not introduce organic materials that can give rise to the formation of migration-enhancing complexes between radionuclides and soluble organic compounds; it should be feasible to construct at a sufficiently high rate; the strength of the

  1. Preliminary mini experiments on leaching of glass. A report of the situation 1979-03-15

    International Nuclear Information System (INIS)

    Blomqvist, G.

    1979-04-01

    The work performed within a project concerning preliminary mini experiments on the leaching of glass up to 1979-03-15 is summarized. It is shown that steady states are not obtained during one month for the investigated elements (Na, Cs, Sr, B) while the concentration of Ca in the leachate decreases to almost zero. The solubility of glass seems to be dependent on the volume. (E.R.)

  2. Preliminary hazards analysis -- vitrification process

    International Nuclear Information System (INIS)

    Coordes, D.; Ruggieri, M.; Russell, J.; TenBrook, W.; Yimbo, P.

    1994-06-01

    This paper presents a Preliminary Hazards Analysis (PHA) for mixed waste vitrification by joule heating. The purpose of performing a PHA is to establish an initial hazard categorization for a DOE nuclear facility and to identify those processes and structures which may have an impact on or be important to safety. The PHA is typically performed during and provides input to project conceptual design. The PHA is then followed by a Preliminary Safety Analysis Report (PSAR) performed during Title 1 and 2 design. The PSAR then leads to performance of the Final Safety Analysis Report performed during the facility's construction and testing. It should be completed before routine operation of the facility commences. This PHA addresses the first four chapters of the safety analysis process, in accordance with the requirements of DOE Safety Guidelines in SG 830.110. The hazards associated with vitrification processes are evaluated using standard safety analysis methods which include: identification of credible potential hazardous energy sources; identification of preventative features of the facility or system; identification of mitigative features; and analyses of credible hazards. Maximal facility inventories of radioactive and hazardous materials are postulated to evaluate worst case accident consequences. These inventories were based on DOE-STD-1027-92 guidance and the surrogate waste streams defined by Mayberry, et al. Radiological assessments indicate that a facility, depending on the radioactive material inventory, may be an exempt, Category 3, or Category 2 facility. The calculated impacts would result in no significant impact to offsite personnel or the environment. Hazardous materials assessment indicates that a Mixed Waste Vitrification facility will be a Low Hazard facility having minimal impacts to offsite personnel and the environment

  3. Preliminary hazards analysis -- vitrification process

    Energy Technology Data Exchange (ETDEWEB)

    Coordes, D.; Ruggieri, M.; Russell, J.; TenBrook, W.; Yimbo, P. [Science Applications International Corp., Pleasanton, CA (United States)

    1994-06-01

    This paper presents a Preliminary Hazards Analysis (PHA) for mixed waste vitrification by joule heating. The purpose of performing a PHA is to establish an initial hazard categorization for a DOE nuclear facility and to identify those processes and structures which may have an impact on or be important to safety. The PHA is typically performed during and provides input to project conceptual design. The PHA is then followed by a Preliminary Safety Analysis Report (PSAR) performed during Title 1 and 2 design. The PSAR then leads to performance of the Final Safety Analysis Report performed during the facility`s construction and testing. It should be completed before routine operation of the facility commences. This PHA addresses the first four chapters of the safety analysis process, in accordance with the requirements of DOE Safety Guidelines in SG 830.110. The hazards associated with vitrification processes are evaluated using standard safety analysis methods which include: identification of credible potential hazardous energy sources; identification of preventative features of the facility or system; identification of mitigative features; and analyses of credible hazards. Maximal facility inventories of radioactive and hazardous materials are postulated to evaluate worst case accident consequences. These inventories were based on DOE-STD-1027-92 guidance and the surrogate waste streams defined by Mayberry, et al. Radiological assessments indicate that a facility, depending on the radioactive material inventory, may be an exempt, Category 3, or Category 2 facility. The calculated impacts would result in no significant impact to offsite personnel or the environment. Hazardous materials assessment indicates that a Mixed Waste Vitrification facility will be a Low Hazard facility having minimal impacts to offsite personnel and the environment.

  4. Development of the Qattara Project, Egypt

    International Nuclear Information System (INIS)

    1978-01-01

    The River Nile, as a huge source of cheap hydroelectric energy, was fully exploited in Egypt upstream of Aswan in 1968 by the construction of the famous Aswan and High Dam Hydroelectric Complex. The growth of demand for electrical power is such that an additional large source of energy is required. The Qattara Project would offer not only an ideal source of low cost power production, but a vital boost for Egypt's national economy. The fundamental idea of the scheme is to channel Mediterranean Sea water into the Qattara Depression, using the difference in levels to produce hydroelectric power. The rate of discharge of sea water into the depression should be equivalent to the rate of evaporation from the lake surface. This situation will arise ten years after starting to fill the lake, when the water has reached a level of 60 m below sea level. The possibility of using PNE to excavate a Mediterranean Sea - Qattara Depression canal was first postulated by the Egyptian Atomic Energy Establishment in 1971. In 1973 a pre-feasibility study was prepared, based on preliminary site investigations performed during the period 1964-1965, namely geological and cartographic surveys, as well as on comparative economic evaluation of various solutions. The study showed clearly that the project including both base-load and peak-load hydroelectric power stations and using nuclear excavation of a canal between the sea and the depression offers a competitive solution for cheap power production. A subsequent feasibility study, which was started in 1975, investigates alternative ways of constructing the canal/tunnel system, using conventional tunnelling and PNE. For the nuclear solution, two cases are considered, one using unlimited yields and another with 150 kt maximum yield. A preliminary assessment of the effects of the explosion and costs of the nuclear component of the project are given. (author)

  5. The Bahrain Burial Mound Project

    DEFF Research Database (Denmark)

    Laursen, Steffen; Johansen, Kasper Lambert

    2007-01-01

    the majority of burial mounds have been removed to make way for roads and housing, and in this process about 8000 mounds have been excavated; of these only c. 265 have been published. In 2006 the Bahrain Directorate for Culture & National Heritage and Moesgaard Museum decided on a collaborative project...... process of linking relevant information to the mounds have been initiated in the course of which excavation data of individual monument is being fed into a relational database. Our preliminary study of the digital maps of the mound cemeteries has revealed an abundance of interesting patterns...... that immediately gave rise to puzzling new questions that will direct the future explorations of the project. Of particular interest is a distinctive new type of elite monuments situated to the south of the so-called Royal Mounds in the centre of the island. The newly discovered type of mounds apparently reflect...

  6. Registered report: Tumour micro-environment elicits innate resistance to RAF inhibitors through HGF secretion

    OpenAIRE

    sprotocols

    2015-01-01

    Authors: David Blum, Samuel LaBarge, The Reproducibility Project: Cancer Biology†* ### Abstract The [Reproducibility Project: Cancer Biology](https://osf.io/e81xl/wiki/home/) seeks to address growing concerns about reproducibility in scientific research by conducting replications of 50 papers in the field of cancer biology published between 2010 and 2012. This Registered Report describes the proposed replication plan of key experiments from “Tumour micro-environment elicits innate res...

  7. Registered report: Widespread potential for growth-factor-driven resistance to anticancer kinase inhibitors2

    OpenAIRE

    sprotocols

    2015-01-01

    Authors: Edward Greenfield, Erin Griner, The Reproducibility Project: Cancer Biology† ### Abstract The [Reproducibility Project: Cancer Biology](https://osf.io/e81xl/wiki/home/) seeks to address growing concerns about reproducibility in scientific research by conducting replications of 50 papers in the field of cancer biology published between 2010 and 2012. This Registered Report describes the proposed replication plan of key experiments from “Widespread potential for growth-factor-d...

  8. Preliminary publications book 2 from project on mineral resources, metallogenesis, and tectonics of northeast Asia

    Science.gov (United States)

    Nokleberg, Warren J.; Miller, Robert J.; Naumova, Vera V.; Khanchuk, Alexander I.; Parfenov, Leonid M.; Kuzmin, Mikhail I.; Bounaeva, Tatiana M.; Obolenskiy, Alexander A.; Rodionov, Sergey M.; Seminskiy, Zhan V.; Diggles, Michael F.

    2003-01-01

    This is the Web version of a CD-ROM publication. This report consists of summary major compilations and syntheses accomplished in the six-year project through April 2003 for the study on the Mineral Resources, Metallogenesis, and Tectonics of Northeast Asia (Eastern and Southern Siberia, Mongolia, Northeastern China, South Korea, and Japan). The major scientific goals and benefits of the project are to: (1) provide a comprehensive international data base on the mineral resources of the region that is the first, extensive knowledge available in English; (2) provide major new interpretations of the origin and crustal evolution of mineralizing systems and their host rocks, thereby enabling enhanced, broad-scale tectonic reconstructions and interpretations; and (3) promote trade and scientific and technical exchanges between the North America and Northeast Asia. Data from the project are providing sound scientific data and interpretations for commercial firms, governmental agencies, universities, and individuals that are developing new ventures and studies in the project area, and for land-use planning studies that deal with both mineral potential issues. Northeast Asia has vast potential for known and undiscovered mineral deposits; however, little information existed in English in the West until publication of products from this project. Consequently, data and interpretations from the project are providing basic knowledge for major scientific, commercial, national, and international endeavors by other interested individuals and groups.

  9. 78 FR 35961 - Pilot Project for Tribal Jurisdiction Over Crimes of Domestic Violence

    Science.gov (United States)

    2013-06-14

    ...This notice proposes procedures for an Indian tribe to request designation as a participating tribe under section 204 of the Indian Civil Rights Act of 1968, as amended, on an accelerated basis, pursuant to the voluntary pilot project described in section 908(b)(2) of the Violence Against Women Reauthorization Act of 2013 (``the Pilot Project''), and also proposes procedures for the Attorney General to act on such a request. This notice also invites public comment on the proposed procedures and solicits preliminary expressions of interest from tribes that may wish to participate in the Pilot Project.

  10. A Vision in Aeronautics: The K-12 Wind Tunnel Project

    Science.gov (United States)

    1997-01-01

    A Vision in Aeronautics, a project within the NASA Lewis Research Center's Information Infrastructure Technologies and Applications (IITA) K-12 Program, employs small-scale, subsonic wind tunnels to inspire students to explore the world of aeronautics and computers. Recently, two educational K-12 wind tunnels were built in the Cleveland area. During the 1995-1996 school year, preliminary testing occurred in both tunnels.

  11. New large solar photocatalytic plant: set-up and preliminary results.

    Science.gov (United States)

    Malato, S; Blanco, J; Vidal, A; Fernández, P; Cáceres, J; Trincado, P; Oliveira, J C; Vincent, M

    2002-04-01

    A European industrial consortium called SOLARDETOX has been created as the result of an EC-DGXII BRITE-EURAM-III-financed project on solar photocatalytic detoxification of water. The project objective was to develop a simple, efficient and commercially competitive water-treatment technology, based on compound parabolic collectors (CPCs) solar collectors and TiO2 photocatalysis, to make possible easy design and installation. The design, set-up and preliminary results of the main project deliverable, the first European industrial solar detoxification treatment plant, is presented. This plant has been designed for the batch treatment of 2 m3 of water with a 100 m2 collector-aperture area and aqueous aerated suspensions of polycrystalline TiO2 irradiated by sunlight. Fully automatic control reduces operation and maintenance manpower. Plant behaviour has been compared (using dichloroacetic acid and cyanide at 50 mg l(-1) initial concentration as model compounds) with the small CPC pilot plants installed at the Plataforma Solar de Almería several years ago. The first results with high-content cyanide (1 g l(-1)) waste water are presented and plant treatment capacity is calculated.

  12. Low-Cost Mapping and Publishing Methods for Landscape Architectural Analysis and Design in Slum-Upgrading Projects

    Directory of Open Access Journals (Sweden)

    Jörg Rekittke

    2011-10-01

    Full Text Available The research project “Grassroots GIS” focuses on the development of low-cost mapping and publishing methods for slums and slum-upgrading projects in Manila. In this project smartphones, collaborative mapping and 3D visualization applications are systematically employed to support landscape architectural analysis and design work in the context of urban poverty and urban informal settlements. In this paper we focus on the description of the developed methods and present preliminary results of this work-in-progress.

  13. Modulation-free bismuth-lead cuprate superconductors: BiPbSr1+xL1-xCuO6 and BiPbSr2Y1-xCaxCu2O8

    International Nuclear Information System (INIS)

    Manivannan, V.; Gopalakrishnan, J.; Rao, C.N.R.

    1991-01-01

    Modulation-free BiPbSrLCuO 6 (L=La, Pr, Nd) and BiPbSr 2 YCu 2 O 8 , which are isotypic with the n=1 and 2 members of the Bi 2 Sr 2 Ca n-1 Cu n O 2n+4 family, have been prepared and characterized. These parent compounds are nonsuperconducting, but when doped with holes by substitution chemistry give modulation-free superconducting cuprates of the general formulas BiPbSr 1+xL1-x CuO 6 and BiPbSr 2 Y 1-x Ca x Cu 2 O 8 , exhibiting maximum T c 's of 24 and 85 K, respectively. Significantly, the hole concentration at the maximum T c is 0.12 in the cuprate family with a single Cu-O layer and 0.22 in that with two Cu-O layers

  14. Sugarcane straw harvest effects on soil quality and plant growth: preliminary data synthesis of a multi-local project running in Brazil

    Science.gov (United States)

    Cherubin, Maurício; Cerri, Carlos E. P.; Feigl, Brigitte J.; Cerri, Carlos C.

    2017-04-01

    Brazil is the largest sugarcane producer in the world, and consequently, it is one of major players in the bioenergy production sector. Despite that, growing demands for bioenergies have raised the interest of Brazilian sugarcane industry to harvest the sugarcane straw left on the field for cellulosic ethanol production and/or bioelectricity cogeneration. However, crop residues have a key role in the soil, affecting directly or indirectly multiple soil functions and related ecosystem services. Therefore, indiscriminate straw harvest could jeopardize soil quality, decreasing its capacity to sustain plant productivity over time. In order to evaluate the potential impacts of sugarcane straw harvest on soil quality and plant growth, we are conducting since 2014 a multi-local project across central-southern Brazil, the main core of sugarcane production in the world. A wide range of soil chemical, physical and biological parameters, as well as, plant biomass production has been quantified under increasing straw harvest intensities. Our preliminary findings have showed that short-term straw harvest management did not affect total organic C stocks; however, high straw harvest led to significant reduction in labile C forms (e.g., microbial biomass C and N), and abundance of microbial communities as well. Sugarcane straw harvest affects soil nutrient cycling, since significant amount of nutrients are removed annually by straw, especially in top (green) leaves. In addition, our data show that straw acts as a thermal insulator, decreasing soil temperature amplitude and keeping soil moisture for a longer time. Straw harvest management did not affect sugarcane yields in the first two crop seasons. Based on this first synthesis of the project, we conclude that short-term sugarcane straw harvest led to soil changes, especially in more sensitive and dynamic properties, which did not affect the plant yield. However, long-term impacts should be monitored towards a better

  15. Status of ITER Cryodistribution and Cryoline project

    Science.gov (United States)

    Sarkar, B.; Vaghela, H.; Shah, N.; Bhattacharya, R.; Choukekar, K.; Patel, P.; Kapoor, H.; Srinivasa, M.; Chang, H. S.; Badgujar, S.; Monneret, E.

    2017-02-01

    The system of ITER Cryodistribution (CD) and Cryolines (CLs) is an integral interface between the Cryoplant systems and the superconducting (SC) magnets as well as Cryopumps (CPs). The project has progressed from the conceptual stage to the industrial stage. The subsystems are at various stages of design as defined by the project, namely, preliminary design, final design and formal reviews. Significant progresses have been made in the prototypes studies and design validations, such as the CL and cold circulators. While one of the prototype CL is already tested, the other one is in manufacturing phase. Performance test of two cold circulators have been completed. Design requirements are unique due the complexity arising from load specifications, layout constraints, regulatory compliance, operating conditions as well as several hundred interfaces. The present status of the project in terms of technical achievements, implications of the changes and the technical management as well as the risk assessment and its mitigation including path forward towards realization is described.

  16. Preliminary design of the advanced quantum beam source

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Byung Cheol; Lee, Jong Min; Jeong, Young Uk; Cho, Sung Oh; Yoo, Jae Gwon; Park, Seong Hee

    2000-07-01

    The preliminary design of the advanced quantum beam source based on a superconducting electron accelerator is presented. The advanced quantum beams include: high power free electron lasers, monochromatic X-rays and {gamma}-rays, high-power medium-energy electrons, high-flux pulsed neutrons, and high-flux monochromatic slow positron beam. The AQBS system is being re-designed, assuming that the SPS superconducting RF cavities used for LEP at CERN will revived as a main accelerator of the AQBS system at KAERI, after the decommissioning of LEP at the end of 2000. Technical issues of using the SPS superconducting RF cavities for the AQBS project are discussed in this report. The advanced quantum beams will be used for advanced researches in science and industries.

  17. Preliminary design of the advanced quantum beam source

    International Nuclear Information System (INIS)

    Lee, Byung Cheol; Lee, Jong Min; Jeong, Young Uk; Cho, Sung Oh; Yoo, Jae Gwon; Park, Seong Hee

    2000-07-01

    The preliminary design of the advanced quantum beam source based on a superconducting electron accelerator is presented. The advanced quantum beams include: high power free electron lasers, monochromatic X-rays and γ-rays, high-power medium-energy electrons, high-flux pulsed neutrons, and high-flux monochromatic slow positron beam. The AQBS system is being re-designed, assuming that the SPS superconducting RF cavities used for LEP at CERN will revived as a main accelerator of the AQBS system at KAERI, after the decommissioning of LEP at the end of 2000. Technical issues of using the SPS superconducting RF cavities for the AQBS project are discussed in this report. The advanced quantum beams will be used for advanced researches in science and industries

  18. Development of a Preliminary Decommissioning Plan Following the International Structure for Decommissioning Costing (ISDC) of Nuclear Installations - 13361

    International Nuclear Information System (INIS)

    Moshonas Cole, Katherine; Dinner, Julia; Grey, Mike; Daniska, Vladimir

    2013-01-01

    The International Structure for Decommissioning Costing (ISDC) of Nuclear Installations, published by OECD/NEA, IAEA and EC is intended to provide a uniform list of cost items for decommissioning projects and provides a standard format that permits international cost estimates to be compared. Candesco and DECOM have used the ISDC format along with two costing codes, OMEGA and ISDCEX, developed from the ISDC by DECOM, in three projects: the development of a preliminary decommissioning plan for a multi-unit CANDU nuclear power station, updating the preliminary decommissioning cost estimates for a prototype CANDU nuclear power station and benchmarking the cost estimates for CANDU against the cost estimates for other reactor types. It was found that the ISDC format provides a well defined and transparent basis for decommissioning planning and cost estimating that assists in identifying gaps and weaknesses and facilitates the benchmarking against international experience. The use of the ISDC can also help build stakeholder confidence in the reliability of the plans and estimates and the adequacy of decommissioning funding. (authors)

  19. Status of the RA research reactor decommissioning project

    International Nuclear Information System (INIS)

    Ljubenov, V.; Nikolic, D.; Pesic, M.; Milosevic, M.; Kostic, Lj.; Steljic, M.; Sotic, O.; Antic, D. . E-mail address of corresponding author: vladan@vin.bg.ac.yu; Ljubenov, V.)

    2005-01-01

    The 6.5 MW heavy water RA research reactor at the VINCA Institute of Nuclear Sciences operated from 1959 to 1984. After 18 years of extended shutdown in 2002 it was decided that the reactor shutdown should be final. Preliminary decommissioning activities have been initiated by the end of 2002 under the Technical Co-operation Programme of the International Atomic Energy Agency. The objective of the project is to implement safe, timely and cost-effective decommissioning of the RA reactor up to unrestricted use of the site. Decommissioning project is closely related to two other projects: Safe Removal of the RA Reactor Spent Nuclear Fuel and Radioactive Waste Management in VINCA Institute. The main phases of the project include preparation of the detailed decommissioning plan, radiological characterization of the reactor site, dismantling and removal of the reactor components and structures, decontamination, final radiological site survey and the documentation of all the activities in order to obtain the approval for unrestricted use of the facility site. In this paper a review of the activities related to the preparation and realization of the RA reactor decommissioning project is given. Status of the project's organizational and technical aspects as for July 2004 are presented and plans for the forthcoming phases of the project realization are outlined. (author)

  20. The outlook for natural gas markets in the GRI baseline projection

    International Nuclear Information System (INIS)

    Holtberg, P.D.

    1990-01-01

    Gas Research Institute is an independent, not-for-profit organization that plans, manages, and develops financing for a cooperative research and development program for the mutual benefit of the natural gas industry and its customers. The research program consists of over 500 active research projects in natural gas supply and end use, and in gas industry operations, as well as related basic research. This paper summarizes the U.S. natural gas demand and supply outlook projected in a preliminary version of the 191 edition of the GRI Baseline Projection of U.S. Energy Supply and Demand. The projection used for this paper is from an early run of the GRI modeling structure. As such, it is subject to substantial revision before the Baseline Projection is finalized. The paper presents a projection of natural gas demand in the major end-use sectors and the slate of supply sources expected to meet that demand over the period from 1989 to 2010

  1. Search for hidden high-Z materials inside containers with the Muon Portal Project

    International Nuclear Information System (INIS)

    Rocca, P La; Bandieramonte, M; Blancato, A A; Bonanno, D; Indelicato, V; Presti, D Lo; Petta, C; Antonuccio, V; Becciani, U; Belluso, M; Billotta, S; Bonanno, G; Costa, A; Garozzo, S; Massimino, P; Belluomo, F; Fallica, G; Leonora, E; Longhitano, F; Longo, S

    2014-01-01

    The Muon Portal is a recently born project that plans to build a large area muon detector for a noninvasive inspection of shipping containers in the ports, searching for the presence of potential fissile (U, Pu) threats. The technique employed by the project is the well-known muon tomography, based on cosmic muon scattering from high-Z materials. The design and operational parameters of the muon portal under construction will be described in this paper, together with preliminary simulation and test results

  2. Search for hidden high-Z materials inside containers with the Muon Portal Project

    Science.gov (United States)

    La Rocca, P.; Antonuccio, V.; Bandieramonte, M.; Becciani, U.; Belluomo, F.; Belluso, M.; Billotta, S.; Blancato, A. A.; Bonanno, D.; Bonanno, G.; Costa, A.; Fallica, G.; Garozzo, S.; Indelicato, V.; Leonora, E.; Longhitano, F.; Longo, S.; Lo Presti, D.; Massimino, P.; Petta, C.; Pistagna, C.; Pugliatti, C.; Puglisi, M.; Randazzo, N.; Riggi, F.; Riggi, S.; Romeo, G.; Russo, G. V.; Santagati, G.; Valvo, G.; Vitello, F.; Zaia, A.; Zappalà, G.

    2014-01-01

    The Muon Portal is a recently born project that plans to build a large area muon detector for a noninvasive inspection of shipping containers in the ports, searching for the presence of potential fissile (U, Pu) threats. The technique employed by the project is the well-known muon tomography, based on cosmic muon scattering from high-Z materials. The design and operational parameters of the muon portal under construction will be described in this paper, together with preliminary simulation and test results.

  3. EPR project construction cost control

    International Nuclear Information System (INIS)

    Duflo, D.; Pouget-Abadie, X.; Dufour, A.; Kauffmann, G.

    2001-01-01

    The EPR project is now managed by EDF in cooperation with the German Utilities. The main engineering activities for this period are related to the preparation of construction project management, deepening of some safety issues, definition of the project technical reference. The EPR project concerns the so-called reference unit, that is an isolated first-off unit, with unit electrical power of about 1500 MW. The construction costs evaluated are those of the nuclear island, the conventional island, site facilities, installation work and the administrative buildings. The EPR project construction cost evaluation method applies to all the equipment installed and commissioned. It requires the availability of a preliminary project detailed enough to identify the bill of quantities. To these quantities are then assigned updated unit prices that are based either on cost bases for similar and recent facilities or taken from request for quotation for similar equipment or result from gains due to contractual conditions benefiting from simplifications in the functional and technical specifications. The input and output data are managed in a model that respects the breakdown on which the evaluation method is based. The structural organization of this method reflects a functional breakdown on the one hand (nuclear island, conventional island, common site elements) and on the other hand a breakdown according to equipment or activity (civil engineering, mechanics, electricity, instrumentation and control). This paper discusses the principle and the method of construction cost evaluation carried out, the cost data base and input and output parameters as well as results and oncoming cost analysis tasks. (author)

  4. The preliminary planning for decommissioning nuclear facilities in Taiwan

    International Nuclear Information System (INIS)

    Li, K.K.

    1993-01-01

    During the congressional hearing in 1992 for a $7 billion project for approval of the fourth nuclear power plant, the public was concerned about the decommissioning of the operating plants. In order to facilitate the public acceptance of nuclear energy and to secure the local capability for appropriate nuclear backend management, both technologically and financially, it is important to have preliminary planning for decommissioning the nuclear facilities. This paper attempted to investigate the possible scope of decommissioning activities and addressed the important regulatory, financial, and technological aspects. More research and development works regarding the issue of decommissioning are needed to carry out the government's will of decent management of nuclear energy from the cradle to the grave

  5. Preliminary results on the Arecibo Pisces-Perseus Supercluster Survey

    Science.gov (United States)

    Cortes, Rosemary; Lebron, Mayra; Jones, Michael G.; Koopmann, Rebecca A.; Haynes, Martha P.; APPSS Team, Undergraduate ALFALFA Team, and the ALFALFA Team

    2018-01-01

    The Arecibo Pisces-Perseus Supercluster Survey (APPSS) aims to exploit the Baryonic Tully-Fisher Relation to derive distances and peculiar velocities of galaxies in and near the main ridge of the Pisces-Perseus Supercluster (PPS), one of the most prominent features of the Cosmic Web in the nearby Universe. The sample of galaxies contains ~ 600 sources in the low-mass range (8 Team institutions in which each group contributes to the analysis of a subset of the HI PPS data. In this poster, we will present the contributions of the U.P.R. team to the APPSS project. We will show the procedure used for the Arecibo HI data analysis, including some examples, and will show our preliminary results.

  6. Ocean surface waves and winds over the north Indian Ocean from satellite altimeter - preliminary results of SAC-NIO joint project

    Digital Repository Service at National Institute of Oceanography (India)

    Sarkar, A.; Rajkumar, R.; Gairola, R.M.; Gohil, B.S.; Vethamony, P.; Rao, L.V.G.

    the respective correlation coefficients. Preliminary results with limited processed data showed that the correlation coefficients are approximately 0.6. Sample maps of wave and wind (satellite derived) in 2.5 degrees x 2.5 degrees grids have been prepared...

  7. 28 CFR 2.48 - Revocation: Preliminary interview.

    Science.gov (United States)

    2010-07-01

    ... 28 Judicial Administration 1 2010-07-01 2010-07-01 false Revocation: Preliminary interview. 2.48....48 Revocation: Preliminary interview. (a) Interviewing officer. A parolee who is retaken on a warrant issued by a Commissioner shall be given a preliminary interview by an official designated by the Regional...

  8. Was Project Management Life Really Better in Apollo?

    Science.gov (United States)

    2010-01-01

    This slide presentation discusses the question of "Was Project Management Life Really Better in Apollo?" Was money really flowing freely all through Apollo? Are we wallowing in nostalgia and comparing current circumstances to a managerial time which did not exist? This talk discusses these and other questions as background for you as today s project managers. There are slides showing the timelines from before the speech that Kennedy gave promising to land a man on the moon, to the early 60's, when the manned space center prepared the preliminary lunar landing mission design, an NASA organization chart from 1970, various photos of the rockets, and the astronauts are presented. The next slides discuss the budgets from the 1960's to the early 1970's. Also the results of a survey of 62 managers, who were asked "What problems pose the greatest obstacles to successful project performance?"

  9. Project organization for automating an industrial power plant

    International Nuclear Information System (INIS)

    Williams, D.R.; McCowen, R.R.

    1988-01-01

    This paper reports on the controls for three boilers and three turbine generators at the power plant at the John Deere Waterloo Works that have been retrofit with a microprocessor based monitoring, control, and optimization system. The factors driving the project in the 15 mW, 500,000 lb/hr, 35 year old plant were reduced electricity costs due to peak shaving, energy conservation, labor savings, reduced maintenance costs and improved reliability. A turnkey design/build arrangement was sought after a preliminary study indicated an attractive return on investment Control system vendors and design/build contractors were evaluated using a group decision making method. A design/build contractor was chosen to do an in-depth study and write specifications for the control system were negotiated with the contractor The project was managed by the Power Plant and Energy Management Department, rather than by the staff department normally responsible for capital projects

  10. Preliminary study on enhancing waste management best practice model in Malaysia construction industry

    Science.gov (United States)

    Jamaludin, Amril Hadri; Karim, Nurulzatushima Abdul; Noor, Raja Nor Husna Raja Mohd; Othman, Nurulhidayah; Malik, Sulaiman Abdul

    2017-08-01

    Construction waste management (CWM) is the practice of minimizing and diverting construction waste, demolition debris, and land-clearing debris from disposal and redirecting recyclable resources back into the construction process. Best practice model means best choice from the collection of other practices that was built for purpose of construction waste management. The practice model can help the contractors in minimizing waste before the construction activities will be started. The importance of minimizing wastage will have direct impact on time, cost and quality of a construction project. This paper is focusing on the preliminary study to determine the factors of waste generation in the construction sites and identify the effectiveness of existing construction waste management practice conducted in Malaysia. The paper will also include the preliminary works of planned research location, data collection method, and analysis to be done by using the Analytical Hierarchy Process (AHP) to help in developing suitable waste management best practice model that can be used in the country.

  11. A digital phantom of the axilla based on the Visible Human Project data set

    Science.gov (United States)

    McCallum, S. J.; Welch, A. E.; Baker, L.

    2001-08-01

    In this paper, we describe the development of a new digital phantom designed for Monte Carlo simulations of breast cancer and particularly positron emission tomography (PET) imaging of the axillary lymph nodes. The phantom was based on data from the Visible Human Project female data set. The phantom covers the head-to-diaphragm regions; 17 major tissue types were segmented and 66 individual lymph nodes were identified. The authors have used the phantom in Monte Carlo simulations to model a reduced field-of-view PET imager based on two flat plate arrays placed on either side of the shoulder. Images used a simple single angle set of projections. The authors have conducted two preliminary studies: one modeling a single-frame PET acquisition 60 min after FDG injection and the other modeling a dynamic PET acquisition simulating four time frames after FDG injection. The dynamic results were processed into parametric images using the Patlak method and show the advantage to be gained by including the temporal information for legion detection. The authors' preliminary results indicate that the performance of such an imager forming projection images is not sufficient for axillary node PET imaging.

  12. The Preliminary Decommissioning Plan of the Dalat Nuclear Research Reactor

    Energy Technology Data Exchange (ETDEWEB)

    Lam, Pham Van; Vien, Luong Ba; Vinh, Le Vinh; Nghiem, Huynh Ton; Tuan, Nguyen Minh; Phuong, Pham Hoai [Nuclear Research Institute, Da Lat (Viet Nam)

    2013-08-15

    Recently, after 25 years of operation, a preliminary decommissioning plan for the Dalat Nuclear Research Reactor (DNRR) has been produced but as yet it has not been implemented due to the continued operations of the reactor. However, from the early phases of facility design and construction and during operation, the aspects that facilitate decommissioning process have been considered. This paper outlines the DNRR general description, the organization that manages the facility, the decommissioning strategy and associated project management, and the expected decommissioning activities. The paper also considers associated cost and funding, safety and environmental issues and waste management aspects amongst other considerations associated with decommissioning a nuclear research reactor. (author)

  13. National plan project of quotas allocation. Reference period

    International Nuclear Information System (INIS)

    2004-06-01

    This document described the national plan project of greenhouse gases quotas allocation, in application of the directive 2003/87/CE. It is a preliminary document providing hypothesis, data and results which could well be modified. It presents in seven chapters the determination of the final quotas quantity, the determination of the final quotas quantity per each activity sectors and per installation, the technical aspects, the community policy and legislation, the public consultation and other criteria analysis. (A.L.B.)

  14. Preliminary Modelling of Radiation Levels at the Fermilab PIP-II Linac

    Energy Technology Data Exchange (ETDEWEB)

    Lari, L. [CERN; Cerutti, F. [CERN; Esposito, L. S. [CERN; Baffes, C. [Fermilab; Dixon, S. J. [Fermilab; Mokhov, N. V. [Fermilab; Rakhno, I. [Fermilab; Tropin, I. S. [Fermilab

    2018-04-01

    PIP-II is the Fermilab's flagship project for providing powerful, high-intensity proton beams to the laboratory's experiments. The heart of PIP-II is an 800-MeV superconducting linac accelerator. It will be located in a new tunnel with new service buildings and connected to the present Booster through a new transfer line. To support the design of civil engineering and mechanical integration, this paper provides preliminary estimation of radiation level in the gallery at an operational beam loss limit of 0.1 W/m, by means of Monte Carlo calculations with FLUKA and MARS15 codes.

  15. The NASA Bed Rest Project

    Science.gov (United States)

    Rhodes, Bradley; Meck, Janice

    2005-01-01

    NASA s National Vision for Space Exploration includes human travel beyond low earth orbit and the ultimate safe return of the crews. Crucial to fulfilling the vision is the successful and timely development of countermeasures for the adverse physiological effects on human systems caused by long term exposure to the microgravity environment. Limited access to in-flight resources for the foreseeable future increases NASA s reliance on ground-based analogs to simulate these effects of microgravity. The primary analog for human based research will be head-down bed rest. By this approach NASA will be able to evaluate countermeasures in large sample sizes, perform preliminary evaluations of proposed in-flight protocols and assess the utility of individual or combined strategies before flight resources are requested. In response to this critical need, NASA has created the Bed Rest Project at the Johnson Space Center. The Project establishes the infrastructure and processes to provide a long term capability for standardized domestic bed rest studies and countermeasure development. The Bed Rest Project design takes a comprehensive, interdisciplinary, integrated approach that reduces the resource overhead of one investigator for one campaign. In addition to integrating studies operationally relevant for exploration, the Project addresses other new Vision objectives, namely: 1) interagency cooperation with the NIH allows for Clinical Research Center (CRC) facility sharing to the benefit of both agencies, 2) collaboration with our International Partners expands countermeasure development opportunities for foreign and domestic investigators as well as promotes consistency in approach and results, 3) to the greatest degree possible, the Project also advances research by clinicians and academia alike to encourage return to earth benefits. This paper will describe the Project s top level goals, organization and relationship to other Exploration Vision Projects, implementation

  16. Advertising Citizen Science: A Trailer for the Citizen Sky Project

    Science.gov (United States)

    Wyatt, Ryan; Price, A.

    2012-01-01

    Citizen Sky is a multi-year, NSF funded citizen science project involving the bright and mysterious variable star epsilon Aurigae. The project was conceived by the IYA 2009 working group on Research Experiences for Students, Teachers, and Citizen-Scientists. Citizen Sky goes beyond simple observing to include a major data analysis component, introducing participants to the full scientific process from background research to paper writing for a peer-reviewed journal. As a means of generating interest in the project, the California Academy of Sciences produced a six-minute "trailer” formatted for both traditional and fulldome planetariums as well as HD and web applications. This talk will review the production process for the trailer as well as the methods of distribution via planetariums, social media, and other venues_along with an update on the Citizen Sky Project as a whole. We will show how to use a small, professionally-produced planetarium trailer to help spread word on a citizen science project. We will also show preliminary results on a study about how participation level/type in the project affects science learning.

  17. The Manhattan Project and its Effects on American Women Scientists

    Science.gov (United States)

    Fletcher, Samuel

    2008-04-01

    There have been many detailed historical accounts of the Manhattan Project, but few have recognized the technical role women scientists and engineers crucially played in the Project's success. Despite their absence from these prominent accounts, recent studies have revealed that, in fact, women participated in every non-combat operation associated with the Manhattan Project. With such extensive participation of women and such a former lack of historical attention upon them, little analysis has been done on how the Manhattan Project might have influenced the prospectus of women scientists after the war. This talk has two aims: 1) to recount some of the technical and scientific contributions of women to the Manhattan Project, and 2) to examine what effects these contributions had on the women's careers as scientists. In other words, I intend offer a preliminary explanation of the extent to which the Manhattan Project acted both as a boon and as a detriment to American women scientists. And finally, I will address what this historical analysis could imply about the effects of current efforts to recruit women into science.

  18. Benchmarking and validation activities within JEFF project

    Directory of Open Access Journals (Sweden)

    Cabellos O.

    2017-01-01

    Full Text Available The challenge for any nuclear data evaluation project is to periodically release a revised, fully consistent and complete library, with all needed data and covariances, and ensure that it is robust and reliable for a variety of applications. Within an evaluation effort, benchmarking activities play an important role in validating proposed libraries. The Joint Evaluated Fission and Fusion (JEFF Project aims to provide such a nuclear data library, and thus, requires a coherent and efficient benchmarking process. The aim of this paper is to present the activities carried out by the new JEFF Benchmarking and Validation Working Group, and to describe the role of the NEA Data Bank in this context. The paper will also review the status of preliminary benchmarking for the next JEFF-3.3 candidate cross-section files.

  19. Benchmarking and validation activities within JEFF project

    Science.gov (United States)

    Cabellos, O.; Alvarez-Velarde, F.; Angelone, M.; Diez, C. J.; Dyrda, J.; Fiorito, L.; Fischer, U.; Fleming, M.; Haeck, W.; Hill, I.; Ichou, R.; Kim, D. H.; Klix, A.; Kodeli, I.; Leconte, P.; Michel-Sendis, F.; Nunnenmann, E.; Pecchia, M.; Peneliau, Y.; Plompen, A.; Rochman, D.; Romojaro, P.; Stankovskiy, A.; Sublet, J. Ch.; Tamagno, P.; Marck, S. van der

    2017-09-01

    The challenge for any nuclear data evaluation project is to periodically release a revised, fully consistent and complete library, with all needed data and covariances, and ensure that it is robust and reliable for a variety of applications. Within an evaluation effort, benchmarking activities play an important role in validating proposed libraries. The Joint Evaluated Fission and Fusion (JEFF) Project aims to provide such a nuclear data library, and thus, requires a coherent and efficient benchmarking process. The aim of this paper is to present the activities carried out by the new JEFF Benchmarking and Validation Working Group, and to describe the role of the NEA Data Bank in this context. The paper will also review the status of preliminary benchmarking for the next JEFF-3.3 candidate cross-section files.

  20. The international STRIPA project. Experimental research on the underground disposal of radioactive waste

    International Nuclear Information System (INIS)

    1983-03-01

    The International Stripa Project is a joint undertaking by a number of countries, carried out under the sponsorship of the OECD Nuclear Energy Agency. It concerns research into the feasibility and safety of disposal of highly radioactive wastes from nuclear power generation, deep underground in crystalline rock. The Project is managed by the Division KBS of the Swedish Nuclear Fuel Supply Company (SKBF), under the direction of representatives from each participating country. This report summarizes the objectives and preliminary results of experimental work performed within the framework of the Stripa Project and that undertaken prior to the establishment of the Project at the Stripa Mine in Sweden. It also describes the part played by the Project in the development of national policies for the safe disposal of radioactive wastes

  1. Project W-320, 241-C-106 sluicing: Civil/structural calculations. Volume 6

    Energy Technology Data Exchange (ETDEWEB)

    Bailey, J.W.

    1998-07-24

    This supporting document has been prepared to make the FDNW calculations for Project W-320 readily retrievable. The purpose of this calculation is to conservatively estimate the weight of equipment and structures being added over Tank 241-C-106 as a result of Project W-320 and combine these weights with the estimated weights of existing structures and equipment as calculated in Attachment 1. The combined weights will be compared to the allowable live load limit to provide a preliminary assessment of loading conditions above Tank 241-C-106.

  2. On Preliminary Test Estimator for Median

    OpenAIRE

    Okazaki, Takeo; 岡崎, 威生

    1990-01-01

    The purpose of the present paper is to discuss about estimation of median with a preliminary test. Two procedures are presented, one uses Median test and the other uses Wilcoxon two-sample test for the preliminary test. Sections 3 and 4 give mathematical formulations of such properties, including mean square errors with one specified case. Section 5 discusses their optimal significance levels of the preliminary test and proposes their numerical values by Monte Carlo method. In addition to mea...

  3. The Lipopolysaccharide Lipid A Long-Chain Fatty Acid Is Important for Rhizobium leguminosarum Growth and Stress Adaptation in Free-Living and Nodule Environments.

    Science.gov (United States)

    Bourassa, Dianna V; Kannenberg, Elmar L; Sherrier, D Janine; Buhr, R Jeffrey; Carlson, Russell W

    2017-02-01

    Rhizobium bacteria live in soil and plant environments, are capable of inducing symbiotic nodules on legumes, invade these nodules, and develop into bacteroids that fix atmospheric nitrogen into ammonia. Rhizobial lipopolysaccharide (LPS) is anchored in the bacterial outer membrane through a specialized lipid A containing a very long-chain fatty acid (VLCFA). VLCFA function for rhizobial growth in soil and plant environments is not well understood. Two genes, acpXL and lpxXL, encoding acyl carrier protein and acyltransferase, are among the six genes required for biosynthesis and transfer of VLCFA to lipid A. Rhizobium leguminosarum mutant strains acpXL, acpXL - /lpxXL - , and lpxXL - were examined for LPS structure, viability, and symbiosis. Mutations in acpXL and lpxXL abolished VLCFA attachment to lipid A. The acpXL mutant transferred a shorter acyl chain instead of VLCFA. Strains without lpxXL neither added VLCFA nor a shorter acyl chain. In all strains isolated from nodule bacteria, lipid A had longer acyl chains compared with laboratory-cultured bacteria, whereas mutant strains displayed altered membrane properties, modified cationic peptide sensitivity, and diminished levels of cyclic β-glucans. In pea nodules, mutant bacteroids were atypically formed and nitrogen fixation and senescence were affected. The role of VLCFA for rhizobial environmental fitness is discussed.

  4. Contrasting the crospovidones functionality as excipients for direct compression

    Directory of Open Access Journals (Sweden)

    Daniel García Ramírez

    2015-03-01

    Full Text Available Specific values of technological properties of excipients allow the establishment of numerical parameters to define and compare their functionality. This study investigates the functionality of Polyplasdones XL and XL10. Parameters studied included tablet disintegration profiles, compactibility profiles and powder flow. The results allowed the establishment of quantitative surrogate functionalities of technological performance, such as absolute number, and as a value relative to the known microcrystalline cellulose type 102. Moreover, the establishment of an explicit functionality to improve the technological performance of two diluents and a model drug was investigated, as was setting up of these functionalities, as quantitative values, to determine the input variables of each material and its probable functionality in a drug product. Disintegration times of pure Polyplasdone XL and its admixtures were around half that of Polyplasdone XL10. The improvement in tablet compactibility was 25-50% greater for Polyplasdone XL10 than Polyplasdone XL. Crospovidones proportions of up to 10% have little effect on the flow properties of other powders, although pure Polyplasdone XL10 and its admixtures display compressibility indexes about 20% greater than Polyplasdone XL. The observed results are in line with a smaller particle size of Polyplasdone XL10 compared to Polyplasdone XL.

  5. WEC3: Wave Energy Converter Code Comparison Project: Preprint

    Energy Technology Data Exchange (ETDEWEB)

    Combourieu, Adrien; Lawson, Michael; Babarit, Aurelien; Ruehl, Kelley; Roy, Andre; Costello, Ronan; Laporte Weywada, Pauline; Bailey, Helen

    2017-01-01

    This paper describes the recently launched Wave Energy Converter Code Comparison (WEC3) project and present preliminary results from this effort. The objectives of WEC3 are to verify and validate numerical modelling tools that have been developed specifically to simulate wave energy conversion devices and to inform the upcoming IEA OES Annex VI Ocean Energy Modelling Verification and Validation project. WEC3 is divided into two phases. Phase 1 consists of a code-to-code verification and Phase II entails code-to-experiment validation. WEC3 focuses on mid-fidelity codes that simulate WECs using time-domain multibody dynamics methods to model device motions and hydrodynamic coefficients to model hydrodynamic forces. Consequently, high-fidelity numerical modelling tools, such as Navier-Stokes computational fluid dynamics simulation, and simple frequency domain modelling tools were not included in the WEC3 project.

  6. SkyMine Carbon Mineralization Pilot Project

    Energy Technology Data Exchange (ETDEWEB)

    Joe Jones; Clive Barton; Mark Clayton; Al Yablonsky; David Legere

    2010-09-30

    This Topical Report addresses accomplishments achieved during Phase 1 of the SkyMine{reg_sign} Carbon Mineralization Pilot Project. The primary objectives of this project are to design, construct, and operate a system to capture CO{sub 2} from a slipstream of flue gas from a commercial coal-fired cement kiln, convert that CO{sub 2} to products having commercial value (i.e., beneficial use), show the economic viability of the CO{sub 2} capture and conversion process, and thereby advance the technology to a point of readiness for commercial scale demonstration and proliferation. The project will also substantiate market opportunities for the technology by sales of chemicals into existing markets, and identify opportunities to improve technology performance and reduce costs at commercial scale. The primary objectives of Phase 1 of the project were to elaborate proven SkyMine{reg_sign} process chemistry to commercial pilot-scale operation and complete the preliminary design ('Reference Plant Design') for the pilot plant to be built and operated in Phase 2. Additionally, during Phase 1, information necessary to inform a DOE determination regarding NEPA requirements for the project was developed, and a comprehensive carbon lifecycle analysis was completed. These items were included in the formal application for funding under Phase 2. All Phase 1 objectives were successfully met on schedule and within budget.

  7. A study on the development of the “Taiwan project management competence scale”

    Directory of Open Access Journals (Sweden)

    Kao I-Chan

    2017-01-01

    Full Text Available On the basis of the 46 competence elements in the International Project Management Association (IPMA ICB Version 3.0 and the PMP competence guidelines in PMBOK® Guide -- Fifth Edition by the Project Management Institute, this study formulates a “Preliminary Draft of the Taiwan Project Management Competence Scale”. After expert review, a pretest was developed for the Taiwan Project Management Competence Scale. With adult students in adult education institutions as the respondents, a pretest was conducted in order to collect data. Confirmatory factor analysis, and reliability analysis were then conducted to construct the “Taiwan Project Management Competence Scale”, which covers the four dimensions of project management of cognitive and conceptual competences, behavioral and technical competences, contextual competences, and moral and ethical competences. It is intended that this scale could be used as reference in future investigations into and measurement of project management competence in Taiwan, thus, facilitating the diagnosis, improvement, and refinement of performance in terms of project management competence.

  8. Preliminary Test for Constitutive Models of CAP

    Energy Technology Data Exchange (ETDEWEB)

    Choo, Yeon Joon; Hong, Soon Joon; Hwang, Su Hyun; Lee, Keo Hyung; Kim, Min Ki; Lee, Byung Chul [FNC Tech., Seoul (Korea, Republic of); Ha, Sang Jun; Choi, Hoon [Korea Electric Power Research Institute, Daejeon (Korea, Republic of)

    2010-05-15

    The development project for the domestic design code was launched to be used for the safety and performance analysis of pressurized light water reactors. As a part of this project, CAP (Containment Analysis Package) code has been developing for the containment safety and performance analysis side by side with SPACE. The CAP code treats three fields (vapor, continuous liquid and dispersed drop) for the assessment of containment specific phenomena, and is featured by assessment capabilities in multi-dimensional and lumped parameter thermal hydraulic cell. Thermal hydraulics solver was developed and has a significant progress now. Implementation of the well proven constitutive models and correlations are essential in other for a containment code to be used with the generalized or optimized purposes. Generally, constitutive equations are composed of interfacial and wall transport models and correlations. These equations are included in the source terms of the governing field equations. In order to develop the best model and correlation package of the CAP code, various models currently used in major containment analysis codes, such as GOTHIC, CONTAIN2.0 and CONTEMPT-LT are reviewed. Several models and correlations were incorporated for the preliminary test of CAP's performance and test results and future plans to improve the level of execution besides will be discussed in this paper

  9. Preliminary Test for Constitutive Models of CAP

    International Nuclear Information System (INIS)

    Choo, Yeon Joon; Hong, Soon Joon; Hwang, Su Hyun; Lee, Keo Hyung; Kim, Min Ki; Lee, Byung Chul; Ha, Sang Jun; Choi, Hoon

    2010-01-01

    The development project for the domestic design code was launched to be used for the safety and performance analysis of pressurized light water reactors. As a part of this project, CAP (Containment Analysis Package) code has been developing for the containment safety and performance analysis side by side with SPACE. The CAP code treats three fields (vapor, continuous liquid and dispersed drop) for the assessment of containment specific phenomena, and is featured by assessment capabilities in multi-dimensional and lumped parameter thermal hydraulic cell. Thermal hydraulics solver was developed and has a significant progress now. Implementation of the well proven constitutive models and correlations are essential in other for a containment code to be used with the generalized or optimized purposes. Generally, constitutive equations are composed of interfacial and wall transport models and correlations. These equations are included in the source terms of the governing field equations. In order to develop the best model and correlation package of the CAP code, various models currently used in major containment analysis codes, such as GOTHIC, CONTAIN2.0 and CONTEMPT-LT are reviewed. Several models and correlations were incorporated for the preliminary test of CAP's performance and test results and future plans to improve the level of execution besides will be discussed in this paper

  10. The central Iowa project.

    Science.gov (United States)

    Allen, H M

    1994-10-01

    This project developed and tested a population-based survey, the HS Form, to examine health and health care in the Central Iowa community. Data from this new collection of proven sets of items were used to compare competing health plans, doctor offices, hospitals, and to develop preliminary norms of the community's insured, in two areas: system performance and health burden. The results showed that the survey: (1) was both feasible and efficient in delivering a comprehensive and generic assessment of consumers and patients; (2) revealed consistent, noteworthy differences between plans and between providers across both sets of criteria; and (3) indicated that there is substantial room for improvement in Central Iowa's health care delivery system from the public's perspective. Recommendations for next steps include: (1) following through on the June 1993 community forum (held to discuss the project's methods and results with local decision makers); (2) broadening the evaluation design to increase sample representativeness; and (3) implementing a pre/post approach to measure changes in plan and provider performance.

  11. Rapid Response Risk Assessment in New Project Development

    Science.gov (United States)

    Graber, Robert R.

    2010-01-01

    A capability for rapidly performing quantitative risk assessments has been developed by JSC Safety and Mission Assurance for use on project design trade studies early in the project life cycle, i.e., concept development through preliminary design phases. A risk assessment tool set has been developed consisting of interactive and integrated software modules that allow a user/project designer to assess the impact of alternative design or programmatic options on the probability of mission success or other risk metrics. The risk and design trade space includes interactive options for selecting parameters and/or metrics for numerous design characteristics including component reliability characteristics, functional redundancy levels, item or system technology readiness levels, and mission event characteristics. This capability is intended for use on any project or system development with a defined mission, and an example project will used for demonstration and descriptive purposes, e.g., landing a robot on the moon. The effects of various alternative design considerations and their impact of these decisions on mission success (or failure) can be measured in real time on a personal computer. This capability provides a high degree of efficiency for quickly providing information in NASA s evolving risk-based decision environment

  12. Green technology foresight of products and materials - some reflections and results from an ongoing Danish project

    DEFF Research Database (Denmark)

    Jørgensen, Michael Søgaard; Pedersen, Thomas Thoning; Falch, Morten

    2005-01-01

    The article presents some methodological and theoretical reflections and some preliminary results from a Danish Green Technology Foresight project about environmental friendly products and materials, where the environmental potentials and risks from three technology areas are analysed: nano- bio...

  13. Modelling lung cancer due to radon and smoking in WISMUT miners: Preliminary results

    International Nuclear Information System (INIS)

    Bijwaard, H.; Dekkers, F.; Van Dillen, T.

    2011-01-01

    A mechanistic two-stage carcinogenesis model has been applied to model lung-cancer mortality in the largest uranium-miner cohort available. Models with and without smoking action both fit the data well. As smoking information is largely missing from the cohort data, a method has been devised to project this information from a case-control study onto the cohort. Model calculations using 256 projections show that the method works well. Preliminary results show that if an explicit smoking action is absent in the model, this is compensated by the values of the baseline parameters. This indicates that in earlier studies performed without smoking information, the results obtained for the radiation parameters are still valid. More importantly, the inclusion of smoking-related parameters shows that these mainly influence the later stages of lung-cancer development. (authors)

  14. The CARIPANDA project: Climate change and water resources in the Adamello Natural Park of Italy

    Science.gov (United States)

    Bocchiola, D.

    2009-04-01

    The three years (2007-2009) CARIPANDA project funded by the Cariplo Foundation of Italy is aimed to evaluate scenarios for water resources in the Adamello natural Park of Italy in a window of 50 years or so (until 2050). The project is led by Ente Parco Adamello and involves Politecnico di Milano, Università Statale di Milano, Università di Brescia, and ARPA Lombardia as scientific partners, while ENEL hydropower Company of Italy joins the project as stake holder. The Adamello Natural Park is a noteworthy resource in the Italian Alps. The Adamello Group is made of several glacierized areas (c. 24 km2), of both debris covered and free ice types, including the widest Italian Glacier, named Adamello, spreading on an area of about c. 18 km2. Also the Adamello Natural Reserve, covering 217 km2 inside the Adamello Park and including the Adamello glaciers, hosts a number of high altitude safeguarded vegetal and animal species, the safety of which is a primary task of the Reserve. Project's activity involves analysis of local climate trend, field campaigns on glaciers, hydrological modelling and remote sensing of snow and ice covered areas, aimed to build a consistent model of the present hydrological conditions and of the areas. Then, properly tailored climate change projections for the area, obtained using local data driven downscaling of climate change projections from GCMs model, are used to infer the likely response to expected climate change conditions. With two years in the project now some preliminary findings can be highlighted and some preliminary trend analysis carried out. The proposed poster provides a resume of the main results of the project insofar, of interest as a benchmark for similar ongoing and foregoing projects about climate change impact on European mountainous natural areas.

  15. Safety analysis and hazard classification for the 100-B/C Site Remediation Project, Phase 1. Revision 1

    International Nuclear Information System (INIS)

    Adam, W.J.; Lehrschall, R.R.; Oestreich, D.K.

    1996-07-01

    The purpose of this report is to document the preliminary hazard classification (PHC) for the initial group of sites to be remediated by the 100-B/C Site Remediation Project. The project is targeted at excavation of contaminated solid from seven waste sites, and the transportation and disposal of these wastes at the Environmental Restoration Disposal Facility. The PHC for these remediation activities is rated as radiological

  16. Preliminary Economics Evaluation and Impact Assessment of The Agribusiness Development Project at RRC Perkerra

    International Nuclear Information System (INIS)

    Cheng'ole, J.M.

    2002-01-01

    The attainment of sustainable food security in the drought-stricken sub-Saharan Africa requires farmer participatory research into the development and adaptation of agricultural technologies and their dissemination for adoption by the farmers. The Agribusiness Development Support Project (ADSP) was initiated in the Arid and semi-arid areas (ASALs) of and surrounding Baringo District to acquire test and disseminate improved vegetable varieties, with significant farmer involvement. The project aims at commercializing horticulture and seed technologies. Three superior onion varieties have been tested on-farm and found to be higher yielding than the traditional varieties. More than 9000 improved fruit tree seedlings have been sold, and their popularity is such that, in favourable weather conditions, the Centre's nurseries cannot effectively meet the demand by farmers and groups. As a result, mechanisms to enlarge the scope of the project to cover more districts and to encourage adoption in current operational area should be affected

  17. Airborne pollutant concentrations and health risks in selected Apulia region (IT) areas: preliminary results from the Jonico-Salentino project

    Science.gov (United States)

    Buccolieri, Riccardo; Genga, Alessandra; De Donno, Antonella; Siciliano, Tiziana; Siciliano, Maria; Serio, Francesca; Grassi, Tiziana; Rispoli, Gennaro; Cavaiola, Mattia; Lionello, Piero

    2017-04-01

    The Jonico-Salentino project (PJS) is a multidisciplinary study funded by Apulia Region (Det. N. 188_RU - 10/11/2015) aiming to assess health risk of people living in the cities of Lecce, Brindisi and Taranto. Citizens are exposed to emissions from industrial sources, biomass burning, vehicular, naval and air traffic, as well as from natural radioactive sources (radon). In this context, this work presents some preliminary results obtained by the Unit of University of Salento (Lecce) during an experimental campaign carried out in the study areas. The campaign is devoted to (i) sample particulate matter (PM), (ii) measure micro-meteorological variables and (iii) evaluate exposure levels of residents to main pollutants. Specifically, PM is sampled using a low volume sampler, while meteorological variables (wind speed components and direction temperature, relative humidity, precipitation and global solar radiation) are measured by advanced instrumentation such as ultrasonic anemometers which allows for the estimation of turbulence fluxes. The early effects of exposure to air pollutants is evaluated by the frequency of micronucleus (a biomarker of DNA damage) in exfoliated buccal cells collected using a soft-bristled toothbrush from oral mucosa of primary school children enrolled in the study. PM concentration data collected during the campaign are characterised from a chemical and morphological point of view; the analysis of different groups of particles allows identifying different natural and anthropogenic emission sources. This is done in conjunction to the investigation of the influence of local meteorology to elucidate the contribution of specific types of sources on final concentration levels. Finally, all data are used to assess the health risk of people living in the study areas as consequence of exposure to airborne pollutants.

  18. Jules Horowitz reactor - presentation of the project and progress report

    International Nuclear Information System (INIS)

    Ballagny, A.; Frachet, S.; Rommens, M.; Guigon, B.; Minguet, J.L.; Dupuy, J.P.; Leydier, C.

    2001-01-01

    The RJH project was launched by CEA some years ago, with the objective to replace, after 2010, the material testing reactors of the previous generation. The objectives are also: to realise a significant step in term of performances, to ensure a high flexibility of the design, in order to host in the future new experiments, which are not completely defined at the project stage, to reach a high level of safety, according to the best current practice. After a summary of the main experimental objectives of the facility, the present paper deals with a detailed technical presentation of the project, resulting from preliminary design studies. The following topics are covered successively: the main functionalities, the resulting design options and technical solutions, the layout of the nuclear facility. (orig.)

  19. Reference Scenario Forecasting: A New Approach to Transport Project Assessment

    DEFF Research Database (Denmark)

    Salling, Kim Bang; Leleur, Steen; Skougaard, Britt Zoëga

    2010-01-01

    This paper presents a new approach to transport project assessment in terms of feasibility risk assessment and reference class forecasting. Normally, transport project assessment is based upon a cost-benefit approach where evaluation criteria such as net present values are obtained. Recent research...... construction cost estimates. Hereafter, a quantitative risk analysis is provided making use of Monte Carlo simulation. This stochastic approach facilitates random input parameters based upon reference class forecasting, hence, a parameter data fit has been performed in order to obtain validated probability...... forecasting (RSF) frame. The RSF is anchored in the cost-benefit analysis (CBA), thus, it provides decision-makers with a quantitative mean of assessing the transport infrastructure project. First, the RSF method introduces uncertainties within the CBA by applying Optimism Bias uplifts on the preliminary...

  20. Preliminary conceptual studies of REX 2000

    International Nuclear Information System (INIS)

    Merchie, F.; Baas, C.; Ballagny, A.; Chagrot, M.; Farny, G.; Barnier, M.; Pattou, A.

    1993-01-01

    Nuclear R and D programs are, to some extent, completely dependent on research reactors availability. In France and others european countries, the major materials testings reactors were built in the sixties and are consequently ageing and reaching the end of their life, some of them having already been shut down. A situation with not a single large research reactor available in first half of next century cannot be imagined, given all the benefits drawn from the use of research reactors. The CEA has therefore started to evaluate the needs for neutron sources in the next four or five decades so as to design the most suitable new facilities to take over from the existing ones. REX 2000 is a new dedicated reactor project intended to meet the needs for fuels and materials testings after the year 2000. The preliminary conceptual studies which have been carried out along the last 18 months are presented and commented. (author)

  1. High Temperature Gas-Cooled Reactor Projected Markets and Preliminary Economics

    Energy Technology Data Exchange (ETDEWEB)

    Larry Demick

    2011-08-01

    This paper summarizes the potential market for process heat produced by a high temperature gas-cooled reactor (HTGR), the environmental benefits reduced CO2 emissions will have on these markets, and the typical economics of projects using these applications. It gives examples of HTGR technological applications to industrial processes in the typical co-generation supply of process heat and electricity, the conversion of coal to transportation fuels and chemical process feedstock, and the production of ammonia as a feedstock for the production of ammonia derivatives, including fertilizer. It also demonstrates how uncertainties in capital costs and financial factors affect the economics of HTGR technology by analyzing the use of HTGR technology in the application of HTGR and high temperature steam electrolysis processes to produce hydrogen.

  2. Light ion production for a future radiobiological facility at CERN: preliminary studies.

    Science.gov (United States)

    Stafford-Haworth, Joshua; Bellodi, Giulia; Küchler, Detlef; Lombardi, Alessandra; Röhrich, Jörg; Scrivens, Richard

    2014-02-01

    Recent medical applications of ions such as carbon and helium have proved extremely effective for the treatment of human patients. However, before now a comprehensive study of the effects of different light ions on organic targets has not been completed. There is a strong desire for a dedicated facility which can produce ions in the range of protons to neon in order to perform this study. This paper will present the proposal and preliminary investigations into the production of light ions, and the development of a radiobiological research facility at CERN. The aims of this project will be presented along with the modifications required to the existing linear accelerator (Linac3), and the foreseen facility, including the requirements for an ion source in terms of some of the specification parameters and the flexibility of operation for different ion types. Preliminary results from beam transport simulations will be presented, in addition to some planned tests required to produce some of the required light ions (lithium, boron) to be conducted in collaboration with the Helmholtz-Zentrum für Materialien und Energie, Berlin.

  3. A preliminary economic feasibility assessment of nuclear desalination in Madura Island

    International Nuclear Information System (INIS)

    Kim, S.-H.; Hwang, Y.-D.; Konishi, T.; Hudi Hastowo

    2005-01-01

    A joint study between KAERI and BATAN, which is entitled 'A preliminary economic feasibility assessment of nuclear desalination in Madura Island', is being conducted under the framework of the Interregional Technical Cooperation Project of IAEA, signed on Oct. 10, 2001 at IAEA. The duration of the project is January 2002 to December 2004. An economic feasibility of nuclear desalination using system-integrated modular advanced reactor (SMART), which will provide Madura Island with electricity and potable water and also support industrialisation and tourism, will be assessed during the project. The scope of this joint study includes the analyses for the short- and long-term energy and water demand as well as the supply plan for Madura Island, evaluation of the site characteristics, environmental impacts and health aspects, technical and economic evaluation of SMART and its desalination system, including the feasibility of its being identified on the Madura Island. KAERI and BATAN are cooperating in conducting a joint study, and IAEA provides technical support and a review of the study products. This paper presents the interim results of the joint study by focussing on the technical and economic aspects of nuclear desalination using SMART in Madura Island. (author)

  4. Recent Results from the SAFIR Project

    Directory of Open Access Journals (Sweden)

    M. Sánchez-Portal

    2014-12-01

    Full Text Available The "Seyfert and star formation Activity in the Far-Infrared" (SAFIR project is aimed at studying the physical nature of the nuclear IR emission and star formation properties of a small sample of nearby Seyfert galaxies observed with the PACS and SPIRE instruments on board the Herschel space observatory. In this paper, we review the achieved results, that reveal the importance of the far-IR range to improve the quality and reliability of the estimates of basic AGN torus parameters, and describe some preliminary outcome from the on-going work on the dust properties of resolved AGN host galaxies.

  5. 76 FR 59578 - List of Nonconforming Vehicles Decided To Be Eligible for Importation

    Science.gov (United States)

    2011-09-27

    ... Carrocerias Cimarron trailer........ 2006-2007 37 Chevrolet 400SS 1995 150 Chevrolet Astro Van 1997 298... Davidson (MC) FX, FL, XL Series....... 1998 253 Harley Davidson (MC) FX, FL, XL Series....... 1999 281 Harley Davidson (MC) FX, FL, XL Series....... 2000 321 Harley Davidson (MC) FX, FL, XL Series....... 2001...

  6. Unobtrusive Multimodal Biometric Authentication: The HUMABIO Project Concept

    Directory of Open Access Journals (Sweden)

    Evangelos Bekiaris

    2008-03-01

    Full Text Available Human Monitoring and Authentication using Biodynamic Indicators and Behavioural Analysis (HUMABIO (2007 is an EU Specific Targeted Research Project (STREP where new types of biometrics are combined with state of the art sensorial technologies in order to enhance security in a wide spectrum of applications. The project aims to develop a modular, robust, multimodal biometrics security authentication and monitoring system which utilizes a biodynamic physiological profile, unique for each individual, and advancements of the state-of-the art in behavioural and other biometrics, such as face, speech, gait recognition, and seat-based anthropometrics. Several shortcomings in biometric authentication will be addressed in the course of HUMABIO which will provide the basis for improving existing sensors, develop new algorithms, and design applications, towards creating new, unobtrusive biometric authentication procedures in security sensitive, controlled environments. This paper presents the concept of this project, describes its unobtrusive authentication demonstrator, and reports some preliminary results.

  7. Quality control and data-handling in multicentre studies: the case of the Multicentre Project for Tuberculosis Research

    Directory of Open Access Journals (Sweden)

    Caloto Teresa

    2001-12-01

    Full Text Available Abstract Background The Multicentre Project for Tuberculosis Research (MPTR was a clinical-epidemiological study on tuberculosis carried out in Spain from 1996 to 1998. In total, 96 centres scattered all over the country participated in the project, 19935 "possible cases" of tuberculosis were examined and 10053 finally included. Data-handling and quality control procedures implemented in the MPTR are described. Methods The study was divided in three phases: 1 preliminary phase, 2 field work 3 final phase. Quality control procedures during the three phases are described. Results: Preliminary phase: a organisation of the research team; b design of epidemiological tools; training of researchers. Field work: a data collection; b data computerisation; c data transmission; d data cleaning; e quality control audits; f confidentiality. Final phase: a final data cleaning; b final analysis. Conclusion The undertaking of a multicentre project implies the need to work with a heterogeneous research team and yet at the same time attain a common goal by following a homogeneous methodology. This demands an additional effort on quality control.

  8. Two Project Methods: Preliminary Observations on the Similarities and Differences between William Heard Kilpatrick's Project Method and John Dewey's Problem-Solving Method

    Science.gov (United States)

    Sutinen, Ari

    2013-01-01

    The project method became a famous teaching method when William Heard Kilpatrick published his article "Project Method" in 1918. The key idea in Kilpatrick's project method is to try to explain how pupils learn things when they work in projects toward different common objects. The same idea of pupils learning by work or action in an…

  9. Preliminary Hazard Classification of the 1714-N, Lead Storage

    International Nuclear Information System (INIS)

    Kerr, N. R.

    1999-01-01

    The 1714-N, -NA and -NB is a building segment that was deactivated under the N Area Deactivation Project. During the deactivation the building was designated as an area to store recycled or reused lead products. This document presents the Preliminary Hazard Classification (PHC) for the continued storage of lead products by Bechtel Hanford, Inc. (BHI). Two types of hazardous substances are the focus of this PHC: lead and residual radiological contamination. An evaluation contained in this PHC concludes that there is little risk from the remaining hazardous substances. It was further concluded that standard institutional controls that are implemented under the BHI contract provide adequate protection to people and the environment. No further safety analysis documentation is required for the continued lead storage

  10. Pim kinases phosphorylate multiple sites on Bad and promote 14-3-3 binding and dissociation from Bcl-XL

    Directory of Open Access Journals (Sweden)

    Hastie C James

    2006-01-01

    Full Text Available Abstract Background Pim-1, 2 and 3 are a group of enzymes related to the calcium calmodulin family of protein kinases. Over-expression of Pim-1 and Pim-2 in mice promotes the development of lymphomas, and up-regulation of Pim expression has been observed in several human cancers. Results Here we show that the pim kinases are constitutively active when expressed in HEK-293 cells and are able to phosphorylate the Bcl-2 family member Bad on three residues, Ser112, Ser136 and Ser155 in vitro and in cells. In vitro mapping showed that Pim-2 predominantly phosphorylated Ser112, while Pim-1 phosphorylated Ser112, but also Ser136 and Ser155 at a reduced rate compared to Ser112. Pim-3 was found to be the least specific for Ser112, and the most effective at phosphorylating Ser136 and Ser155. Pim-3 was also able to phosphorylate other sites in Bad in vitro, including Ser170, another potential in vivo site. Mutation of Ser136 to alanine prevented the phosphorylation of Ser112 and Ser155 by Pim kinases in HEK-293 cells, suggesting that this site must be phosphorylated first in order to make the other sites accessible. Pim phosphorylation of Bad was also found to promote the 14-3-3 binding of Bad and block its association with Bcl-XL. Conclusion All three Pim kinase family members predominantly phosphorylate Bad on Ser112 and in addition are capable of phosphorylating Bad on multiple sites associated with the inhibition of the pro-apoptotic function of Bad in HEK-293 cells. This would be consistent with the proposed function of Pim kinases in promoting cell proliferation and preventing cell death.

  11. Designing Your Community-Based Learning Project: Five Questions To Ask about Your Pedagogical and Participatory Goals.

    Science.gov (United States)

    Carter, Marion; Cadge, Wendy; Rivero, Estela; Curran, Sara

    2002-01-01

    Presents a set of five questions to be considered in the preliminary planning of a community-based learning (CBL) project. Discusses each question and outlines advantages and disadvantages of decisions, focusing on competing interests of students, instructors, and partner organizations. (Author/KDR)

  12. 23 CFR 645.109 - Preliminary engineering.

    Science.gov (United States)

    2010-04-01

    ... 23 Highways 1 2010-04-01 2010-04-01 false Preliminary engineering. 645.109 Section 645.109 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION ENGINEERING AND TRAFFIC OPERATIONS UTILITIES Utility Relocations, Adjustments, and Reimbursement § 645.109 Preliminary engineering. (a) As...

  13. Macroalgae for CO2 Capture and Renewable Energy - A Pilot Project

    Energy Technology Data Exchange (ETDEWEB)

    Wiley, Kristine [Gas Technology Inst., Des Plaines, IL (United States)

    2011-01-31

    The objective of this project was to demonstrate, at a pilot scale, the beneficial use of carbon dioxide (CO2) through a technology designed to capture CO2 from fossil-fuel fired power plant stack gas, generating macroalgae and converting the macroalgae at high efficiency to renewable methane that can be utilized in the power plant or introduced into a natural gas pipeline. The proposed pilot plant would demonstrate the cost-effectiveness and CO2/ NOx flue-gas removal efficiency of an innovative algal scrubber technology where seaweeds are grown out of water on specially-designed supporting structures contained within greenhouses where the plants are constantly bathed by recycled nutrient sprays enriched by flue gas constituents. The work described in this document addresses Phase 1 of the project only. The scope of work for Phase 1 includes the completion of a preliminary design package; the collection of additional experimental data to support the preliminary and detailed design for a pilot scale utilization of CO2 to cultivate macroalage and to process that algae to produce methane; and a technological and economic analysis to evaluate the potential of the system. Selection criteria for macroalgae that could survive the elevated temperatures and potential periodic desiccation of near desert project sites were identified. Samples of the selected macroalgae species were obtained and then subjected to anaerobic digestion to determine conversions and potential methane yields. A Process Design Package (PDP) was assembled that included process design, process flow diagram, material balance, instrumentation, and equipment list, sizes, and cost for the Phase 2 pilot plant. Preliminary economic assessments were performed under the various assumptions made, which are purposely conservative. Based on the results, additional development work should be conducted to delineate the areas for improving efficiency, reducing

  14. Project of compact accelerator for cancer proton therapy; Progetto di acceleratore compatto per terapia oncologica con protoni (TOP)

    Energy Technology Data Exchange (ETDEWEB)

    Picardi, L; Ronsivalle, C; Vignati, A [ENEA, Cntro Ricerche Frascati, Rome (Italy). Dip. Innovazione

    1995-04-01

    The status of the sub-project `Compact Accelerator` in the framework of the Hadrontherapy Project leaded by Prof. Amaldi is described. Emphasis is given to the reasons of the use of protons for radiotherapy applications, to the results of the preliminary design studies of four types of accelerators as possible radiotherapy dedicated `Compact Accelerator` and to the scenario of the fonts of financial resources.

  15. Mining-metallurgical projects for the production of uranium concentrates

    International Nuclear Information System (INIS)

    Ajuria-Garza, S.

    1983-01-01

    This report presents an overall view of a complete project for a mining-metallurgical complex for the production of uranium concentrates. Relevant aspects of each important topic are discussed as parts of an integrated methodology. The principal project activities are analyzed and the relationships among the various factors affecting the design are indicated. A list of 96 principal activities is proposed as an example. These activities are distributed in eight groups: initial evaluations preliminary feasibility studies, project engineering, construction, industrial operation, decommissioning and post-decommissioning activities. The environmental impact and the radiological risks due to the construction and operation of the mining metallurgical complex are analyzed. The principles of radiological protection and the regulations, standards and recommendations for radiological protection in uranium mines and mills are discussed. This report is also a guide to the specialized literature: a bibliography with 765 references is included. (author)

  16. Preliminary design county plan Zeeland

    International Nuclear Information System (INIS)

    1987-01-01

    The preliminary design 'Streekplan Zeeland' (Country plan Zeeland, with regard to the location of additional nuclear power plants in Zeeland, the Netherlands) has passed through a consultation and participation round. Thereupon 132 reactions have been received. These have been incorporated and answered in two notes. This proposal deals with the principal points of the preliminary design and treats also the remarks of the committees Environmental (town and country) Planning (RO), Provincial (town and country) Planning Committee (PPC) and Association of Communities of Zeeland (VZG), on the reply notes. The preliminary design with the modifications, collected in appendix 3, is proposed to be the starting point in the drawing-up of the design-country-plan. This design subsequently will pass the formal country-plan procedure. (author). 1 fig

  17. The influence of client brief and change order in construction project

    Science.gov (United States)

    Mahat, N. A. A.; Adnan, H.

    2018-02-01

    Construction briefing is a statement of needs about intentions and projects objectives. Briefing process is the preliminary stage in the design process and successful briefing can achieve project delivery right on target time, cost and quality of project confidently. Although there are many efforts to approach client’s requirement and needs for a project, it is still not collected adequately to make proper solutions in design. Thus, these may lead the client to include change orders during the construction phase. This paper is concerned toward the influence of client’s briefing of a construction project that impact on the change order on the construction works. The research objective is to identify the influence of client’s brief on change orders, therefore, the aims of the research is to reduce change orders in project delivery. This research adopted both qualitative and quantitative data collection methods which are content analysis and semi structure interview. The findings highlight factors contributing to change orders and the essential attributes of clients during the briefing stage that may help minimise them.

  18. Project planning of Gen-IV sodium cooled fast reactor technology

    Energy Technology Data Exchange (ETDEWEB)

    Yoo, Jaewoon; Joo, H. K.; Cho, C. H.; Kim, Y. G.; Lee, D. U.; Jin, M. W.

    2013-05-15

    The project program will be established to shorten the design schedule by sharing the design man power and experimental facility, and by introducing the proven technology through international collaboration and the project plan including preliminary specific design, technology validation and fuel design validation plan will be more detail by reviewing the plan at the International Technical Review Meeting (ITRM). Periodic project progress review meeting will be held to find the technical issues and to resolve them. The results of the progress review meeting will be reflected into the final assessment of research project. The project progress review meeting will be held every quarter and external expert will also participate in the meeting. In parallel with the PGSFR development, innovative small modular SFR will be developed aiming to the international nuclear market. The system and component technologies of both system can be shared but innovative concept will be implemented into the design. Ultra long life core design concept and supercritical CO{sub 2} Brayton cycle will be considered as the innovative concept for enhancing the plant economy and safety.

  19. Project planning of Gen-IV sodium cooled fast reactor technology

    International Nuclear Information System (INIS)

    Yoo, Jaewoon; Joo, H. K.; Cho, C. H.; Kim, Y. G.; Lee, D. U.; Jin, M. W.

    2013-05-01

    The project program will be established to shorten the design schedule by sharing the design man power and experimental facility, and by introducing the proven technology through international collaboration and the project plan including preliminary specific design, technology validation and fuel design validation plan will be more detail by reviewing the plan at the International Technical Review Meeting (ITRM). Periodic project progress review meeting will be held to find the technical issues and to resolve them. The results of the progress review meeting will be reflected into the final assessment of research project. The project progress review meeting will be held every quarter and external expert will also participate in the meeting. In parallel with the PGSFR development, innovative small modular SFR will be developed aiming to the international nuclear market. The system and component technologies of both system can be shared but innovative concept will be implemented into the design. Ultra long life core design concept and supercritical CO 2 Brayton cycle will be considered as the innovative concept for enhancing the plant economy and safety

  20. Data Management Plan: HarassMap

    OpenAIRE

    Reem Wael

    2017-01-01

    HarassMap is an Egyptian organisation that works to create an environment where sexual harassment is not tolerated, and where individuals and institutions take action against it. For the purpose of this project, the project team cleaned up, organised, and made openly available for the public to access and use through a web portal, three main types of data: Crowdsourced reports of sexual harassment incidents (reports on HarassMap’s online reporting and mapping system) - CSV and XL...