WorldWideScience

Sample records for production opportunities risks

  1. A qualitative risk assessment approach for Swiss dairy products: opportunities and limitations.

    Science.gov (United States)

    Menéndez González, S; Hartnack, S; Berger, T; Doherr, M; Breidenbach, E

    2011-05-01

    Switzerland implemented a risk-based monitoring of Swiss dairy products in 2002 based on a risk assessment (RA) that considered the probability of exceeding a microbiological limit value set by law. A new RA was launched in 2007 to review and further develop the previous assessment, and to make recommendations for future risk-based monitoring according to current risks. The resulting qualitative RA was designed to ascertain the risk to human health from the consumption of Swiss dairy products. The products and microbial hazards to be considered in the RA were determined based on a risk profile. The hazards included Campylobacter spp., Listeria monocytogenes, Salmonella spp., Shiga toxin-producing Escherichia coli, coagulase-positive staphylococci and Staphylococcus aureus enterotoxin. The release assessment considered the prevalence of the hazards in bulk milk samples, the influence of the process parameters on the microorganisms, and the influence of the type of dairy. The exposure assessment was linked to the production volume. An overall probability was estimated combining the probabilities of release and exposure for each combination of hazard, dairy product and type of dairy. This overall probability represents the likelihood of a product from a certain type of dairy exceeding the microbiological limit value and being passed on to the consumer. The consequences could not be fully assessed due to lack of detailed information on the number of disease cases caused by the consumption of dairy products. The results were expressed as a ranking of overall probabilities. Finally, recommendations for the design of the risk-based monitoring programme and for filling the identified data gaps were given. The aims of this work were (i) to present the qualitative RA approach for Swiss dairy products, which could be adapted to other settings and (ii) to discuss the opportunities and limitations of the qualitative method. © 2010 Blackwell Verlag GmbH.

  2. Biochar production and applications in sub-Saharan Africa: opportunities, constraints, risks and uncertainties.

    Science.gov (United States)

    Gwenzi, Willis; Chaukura, Nhamo; Mukome, Fungai N D; Machado, Stephen; Nyamasoka, Blessing

    2015-03-01

    Sub-Saharan Africa (SSA) experiences soil degradation, food and livelihood insecurity, environmental pollution and lack of access to energy. Biochar has gained international research attention, but few studies have investigated the potential of biochar to address the challenges in SSA. This paper seeks to identify and evaluate generic potential opportunities and constraints associated with biochar application in sub-Saharan Africa using Zimbabwe as case study. Specific objectives were to; (1) identify and quantify feedstocks for biochar production; (2) review literature on the biochar properties, and evaluate its potential applications in agriculture, environmental remediation and energy provision, and (3) identify research gaps, risks and constraints associated with biochar technology. Biochar feedstocks in Zimbabwe were estimated to be 9.9 Mton yr(-1), predominantly derived from manure (88%) and firewood (10%). This will yield 3.5, 1.7 and 3.1 Mton yr(-1) of biochar, bio-oil and synthetic gas, respectively. Land application of the 3.5 Mton yr(-1) of biochar (≈63% C) would sequester approximately 2.2 Mton yr(-1) of soil carbon in Zimbabwe alone, while simultaneously minimizing the environmental and public health risks, and greenhouse gas emissions associated with solid organic wastes. Biochar potentially enhances soil and crop productivity through enhanced nutrient and soil moisture availability, amelioration of acidic soils and stimulation of microbial diversity and activity. Due to its excellent adsorption properties, biochar has potential applications in industrial and environmental applications including water and wastewater treatment, remediation and revegetation of contaminated soils and water. Biochar products have energy values comparable or higher than those of traditional biomass fuels; thereby making them ideal alternative sources of energy especially for poor households without access to electricity. Before the benefits of biochar can be

  3. International ROR: risk, opportunity, reward

    International Nuclear Information System (INIS)

    Krentz, D.; Gair, J.

    1996-01-01

    Norcen Energy Resources Limited's pursuit of international oil and gas opportunities since the late 1980s were outlined. By 1994 Norcen had exploration and production concessions in 12 countries stretching from Algeria, Russia, Argentina, Indonesia to offshore Australia. The company had seen its share of risks, opportunities and rewards. Since 1994 international efforts of the Company have been focused on lower risk opportunities with exploration upside in defined core areas of South America, particularly in Venezuela, a country with conventional, heavy and ultra-heavy oil resources exceeding that of Saudi Arabia. These, and other similar foreign investments in the formerly closed national oil industries of South America have been greatly facilitated by the political liberalization, economic reforms and stabilization that have taken place there over the past ten years. The story of Norcen's successful bidding on the Oritupano-Leona production block in 1993 and Delta Centro exploration block in 1996 was the subject of this presentation

  4. OPPORTUNITIES AND RISKS IN THE PRODUCTION AND MARKETING OF GENETICALLY MODIFIED ORGANISMS NUTRITIONAL USES

    Directory of Open Access Journals (Sweden)

    Nica-Badea Delia

    2013-02-01

    Full Text Available This paper presents data and arguments on GMO nutritional purposes, assessingrisks, development and production and marketing stage towards the achievement of foodsafety requirements. Dynamic surface is fast transgenic crops from 1.7 million hectares in1996 to 160 million hectares in 2011. Current culture focuses on tolerance of transgenicplants to herbicides, 75% of the total (glyphosate tolerance, eliminating insect pests of plant.Situation licenses PMG: corn (65, cotton (39, rape (15, potatoes and soybeans (14 each.In our country, soybeans and corn were the only GMP grown commercially cultivated area in2011 was ≤ 50.0000 Ha. In food, genetic engineering techniques are directed at changing theproportion of macro and micro nutrients, elimination or reduction of the compounds withadverse effect on health, introducing or increasing concentrations of substances havingproper behavior. Adoption in 2004, the new EU legislation on GMOs seeks to protect therights of producers, traders and consumers to choose and benefit from tools such astraceability, labeling and post-market monitoring. Modern biotechnology is primarily a veryimportant source of income. GMPs global market was estimated for 2008 at $ 7.5 billion.Analyzing the stakes and implications of trade in GMO products can conclude that: there isno conventional cargo "zero GMO" products "free of GMO" are rare - higher prices by 30-50%. Regardless of why GMOs have been created and marketed not be ignored that presentsa potential risk factor.

  5. Towards sustainable soy : an assessment of opportunities and risks for soybean production based on a case study Brazil

    NARCIS (Netherlands)

    Berkum, van S.; Bindraban, P.S.

    2008-01-01

    This study investigates opportunities for and implications of expanding soybean production in developing countries. Increasing soybean production is expected to take place mainly in Latin America. However the international community is increasingly concerned about managing the natural resources in

  6. Managing Risk and Opportunity

    DEFF Research Database (Denmark)

    Andersen, Torben Juul; Garvey, Maxine; Roggi, Oliviero

    outcomes. This topic is timely and of interest both to the academic community as well as to practicing managers, executives, and directors. The volume focuses on contemporary risk leadership issues based on recent research insights but avoids excessive technical language and mathematical formulas. The book...... is framed around the challenges imposed on executives and directors in dealing with an increasingly complex and unpredictable world. This requires a new risk leadership focus that not only avoids the downside risks but also considers ways to exploit the upside potential offered by a dynamic environment....... The underlying logic is built on the principles of financial economics where benefits derive from reducing bankruptcy costs and increasing future cash inflows. This provides a stringent framework for analyzing the effect of different risk management actions and behaviors in effective risk-taking organizations...

  7. Managing Risk and Opportunity

    DEFF Research Database (Denmark)

    Andersen, Torben Juul; Garvey, Maxine; Roggi, Oliviero

    outcomes. This topic is timely and of interest both to the academic community as well as to practicing managers, executives, and directors. The volume focuses on contemporary risk leadership issues based on recent research insights but avoids excessive technical language and mathematical formulas. The book...... is framed around the challenges imposed on executives and directors in dealing with an increasingly complex and unpredictable world. This requires a new risk leadership focus that not only avoids the downside risks but also considers ways to exploit the upside potential offered by a dynamic environment...

  8. Production of unconventional natural gas. Risks and opportunities of fracking; Foerderung von unkonventionellem Erdgas. Risiken und Chancen des Fracking

    Energy Technology Data Exchange (ETDEWEB)

    Toepfer, Frank-Rainer; Kreutz, Giannina [Baker und McKenzie, Berlin (Germany)

    2013-07-15

    Through its legislation for the promotion of electricity production from renewable resources and the nuclear phase-out the German Federal Republic has taken decisive steps in orienting its energy policy towards the envisioned energy turnaround. Production of natural gas from unconventional natural gas sources could assist in implementing this policy while at the same time improving Germany's energy self-sufficiency. After intensive discussions in the public arena as well as in expert rounds the Federal Ministers of the Environment and of Economic Affairs have agreed on a draft for an ordinance on the exploitation of unconventional gas resources by means of hydraulic fracturing (fracking). On sober analysis of the risks and opportunities involved in this technology one obtains an overall picture which, taking into account the differentiated view it affords on the various aspects involved, ultimately reveals that, on condition of strict compliance with the necessary requirements, for all the risks associated with it fracking is a viable option for Germany.

  9. Contract of Shared Risk. New investment opportunities

    International Nuclear Information System (INIS)

    Carta Petrolera

    1997-01-01

    In order to offering to the private capital, new investment opportunities in exploration and production in Colombia, ECOPETROL settled down since 1996 the Contract of Shared Risk. This is a novel recruiting modality, because the shared risk is applied to the exploratory areas that are assigned for the direct operation of ECOPETROL

  10. Telemedicine: opportunities and risks

    International Nuclear Information System (INIS)

    Vogl, R.

    2002-01-01

    Problem. Due to the rapid progress in the fields of information technology and data networks, telemedicine applications are growing in number. Besides curative telemedicine, the electronic exchange of medical data and the integration of health information systems between health care providers is gaining importance. Through the improved accessibility of electronic patient record information, considerable risks arise.Methods. A project for the interconnection of medical picture archiving and communication systems (PACS) between several hospitals is presented and the possibilities for further developing such networking systems utilizing new software technologies for transparent data access between different locations (GRID) and for decision support (software agents) are considered.Results. The availability of the electronic patient record via the data network and the perspective of semi intelligent software systems automatically preparing the data bears great potential for a boost in treatment quality and efficiency. Systems for unique electronic patient identification and for secure digital signature are a prerequisite, but per se not enough to ensure the protection of data against illegitimate access.Conclusion. Despite quality and efficiency benefits, challenges in the protection of sensible data and in the change of the physicians role result. (orig.) [de

  11. On Risks and Opportunities in Financial Markets

    OpenAIRE

    Lansdorp, Simon

    2012-01-01

    textabstractInvesting in financial securities inevitably involves risks on the one hand and opportunities on the other hand. This thesis bundles four different studies on risks and/or opportunities in financial markets. In one study, we examine the cross-sectional explanatory power of different risk-measures in pricing U.S. stocks and find that investors dislike downside risk. In the second study, we show that conventional short-term reversal strategies exhibit dynamic exposures to systematic...

  12. On Risks and Opportunities in Financial Markets

    NARCIS (Netherlands)

    S.D. Lansdorp (Simon)

    2012-01-01

    textabstractInvesting in financial securities inevitably involves risks on the one hand and opportunities on the other hand. This thesis bundles four different studies on risks and/or opportunities in financial markets. In one study, we examine the cross-sectional explanatory power of different

  13. Medium and Long-term Opportunities and Risks of the Biotechnological Production of Bulk Chemicals from Renewable Resources. The Potential of White Biotechnology. The BREW Project. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Patel, M.; Crank, M.; Dornburg, V.; Hermann, B.; Roes, L. [Department of Science, Technology and Society NWS, Utrecht University, Utrecht (Netherlands); Huesing, B. [Fraunhofer Institute for Systems and Innovation Research FhG-ISl, Karlsruhe (Germany); Overbeek, L. [Plant Research International PRI, Wageningen (Netherlands); Terragni, F.; Recchia, E. [CERISS, Centro per I' Educazione, la Ricerca, I' lnformazione su Scienza e Society, Milan (Italy)

    2006-09-15

    This study investigates the medium and long-term opportunities and risks of the biotechnological production of organic chemicals. The objective is to gain better understanding of the techno-economic and the societal viability of White Biotechnology in the coming decades. The key research questions are which products could be made with White Biotechnology, whether these products can contribute to savings of energy use and greenhouse gas (GHG) emissions, under which conditions the products become economically viable, which risks may originate from the use of genetically modified organisms (GMO) in fermentation and what the public perception is. The main purpose of Chapter 2 is to provide an overview of emerging key White Biotechnology products and to explain which chemicals could be produced on their basis. For a selection of these products, detailed environmental and economic assessments are conducted in Chapter 3 (in specific terms, i.e. per tonne of product). Chapter 3 discusses also the so-called Generic Approach which is the methodology we developed and applied to assess future processes and processes, for which very little information is available. In Chapter 4, three scenario projections are developed for Europe (EU-25), thereby assuming benign, moderate and disadvantageous conditions for bio-based chemicals. The purpose of this chapter is hence to understand to which extent restructuring of the chemical sector might occur under which conditions. In Chapter 5, the risks related to the use of White Biotechnology are addressed. The main purpose of this chapter is to give insight into the main risk components influencing the overall risk and of the knowledge gaps. Both conventional risks (e.g., human toxicity and accidents) and risks related to generic modification (e.g., horizontal gene transfer) are analyzed. Since the public perception may play an important role for the implementation of White Biotechnology on a large scale, these issues are discussed in

  14. Biotechnological opportunities to biopolymers production

    International Nuclear Information System (INIS)

    Ballesteros, M.; Ballesteros, I.; Oliva, J.M.

    1994-01-01

    The increasing garbage mountain is more and more recognized as an ecological threat, Space for landfills is limited and additional Incineration capacities require high capital investments and pose additional environmental problems. This paper discusses the current development and utilization state of new biodegradable polymers. Special attention is focused on microbiological production of poli-D-Beta-hydroxybutyrate acid (PHB), reviewing the metabolic regulation of PHB and the elements to determine its industrial scale production. (Author) 6 refs

  15. Nontimber forest product opportunities in Alaska.

    Science.gov (United States)

    David Pilz; Susan J. Alexander; Jerry Smith; Robert Schroeder; Jim. Freed

    2006-01-01

    Nontimber forest products from southern Alaska (also called special forest products) have been used for millennia as resources vital to the livelihoods and culture of Alaska Natives and, more recently, as subsistence resources for the welfare of all citizens. Many of these products are now being sold, and Alaskans seek additional income opportunities through...

  16. Risk-based regulation: Challenges and opportunities

    International Nuclear Information System (INIS)

    Bari, R.A.

    1995-01-01

    Over the last twenty years, man has witnessed a gradual but steady movement toward increased usage of risk-based methods and results in the regulatory process. The ''risk perspective'' as a supportive view to existing (non-risk-based or deterministic) information used in decision making has a firm foothold now in most countries that regulate nuclear power. Furthermore, in the areas outside the nuclear power field, such as health risk assessment, risk-based information is used increasingly to make decisions on potential impacts of chemical, biological, and radiological exposures. Some of the principal concepts and issues that are pertinent to risk-based regulation are reviewed. There is a growing interest in most countries in the use of risk-based methods and results to facilitate decision-making associated with regulatory processes. A summary is presented of the challenges and opportunities related to expanded use of risk-based regulation

  17. Biorefinery opportunities for the forest products industries

    Science.gov (United States)

    Alan W. Rudie

    2013-01-01

    Wood residues offer biorefinery opportunities for new products in our industries including fuel and chemicals. But industry must have two capabilities to succeed with biorefineries. Most forest products companies already have the first capability: knowing where the resource is, how to get it, and how much it will cost. They will need to integrate the acquisition of...

  18. Opportunities to reduce risk associated with nuclear logging techniques

    International Nuclear Information System (INIS)

    Wraight, P.D.; Robinson, E.; de Fleurieu, R.

    1991-01-01

    Nuclear logging provides petroleum exploration and production companies with data that are critical to their decisions and operations. Because this type data is so important, environmentally conscious well-logging and service companies are constantly reviewing the risks to people and environment associated with nuclear sources with the ALARA (as low as reasonably achievable) principle in mind. Opportunities to additionally reduce risks, which can be accomplished only with the active involvement of oil companies, are proposed in this paper

  19. Opportunities for the forest products industries

    Science.gov (United States)

    Alan W. Rudie

    2011-01-01

    The concept of sustainable harvests is not new to lumber and paper companies—they have been concerned about it and been practicing it for decades, long before it became the headline in a newspaper article. After decades of static products and markets, the industry is offered an opportunity to add products in a new business sector—fuels and chemicals. Although paper...

  20. Analysis of risks and investments’ opportunities in water sector

    Directory of Open Access Journals (Sweden)

    Fjona Zeneli

    2016-01-01

    These opportunities result from the difference between water supply and water demand; an increasingly difference that requires capital investments in production and water treatment technologies. Investments need to be combined with the knowledge on the legislation, regulatory framework and technological developments. This article may serve to clarify type of investments in drinking water sector, known by literature, to identify opportunities of investment in this sector, indicating the theoretical framework of beta and alpha risk ratio coefficient calculation and to suggest how these types of investments can be allocated to the investment portfolios.

  1. Additive manufacturing in production: challenges and opportunities

    Science.gov (United States)

    Ahuja, Bhrigu; Karg, Michael; Schmidt, Michael

    2015-03-01

    Additive manufacturing, characterized by its inherent layer by layer fabrication methodology has been coined by many as the latest revolution in the manufacturing industry. Due to its diversification of Materials, processes, system technology and applications, Additive Manufacturing has been synonymized with terminology such as Rapid prototyping, 3D printing, free-form fabrication, Additive Layer Manufacturing, etc. A huge media and public interest in the technology has led to an innovative attempt of exploring the technology for applications beyond the scope of the traditional engineering industry. Nevertheless, it is believed that a critical factor for the long-term success of Additive Manufacturing would be its ability to fulfill the requirements defined by the traditional manufacturing industry. A parallel development in market trends and product requirements has also lead to a wider scope of opportunities for Additive Manufacturing. The presented paper discusses some of the key challenges which are critical to ensure that Additive Manufacturing is truly accepted as a mainstream production technology in the industry. These challenges would highlight on various aspects of production such as product requirements, process management, data management, intellectual property, work flow management, quality assurance, resource planning, etc. In Addition, changing market trends such as product life cycle, mass customization, sustainability, environmental impact and localized production will form the foundation for the follow up discussion on the current limitations and the corresponding research opportunities. A discussion on ongoing research to address these challenges would include topics like process monitoring, design complexity, process standardization, multi-material and hybrid fabrication, new material development, etc.

  2. Wildfire Risk Management: Challenges and Opportunities

    Science.gov (United States)

    Thompson, M.; Calkin, D. E.; Hand, M. S.; Kreitler, J.

    2014-12-01

    In this presentation we address federal wildfire risk management largely through the lens of economics, targeting questions related to costs, effectiveness, efficiency, and tradeoffs. Beyond risks to resources and assets such as wildlife habitat, watersheds, and homes, wildfires present financial risk and budgetary instability for federal wildfire management agencies due to highly variable annual suppression costs. Despite its variability, the costs of wildfire management have continued to escalate and account for an ever-growing share of overall agency budgets, compromising abilities to attain other objectives related to forest health, recreation, timber management, etc. Trends associated with a changing climate and human expansion into fire-prone areas could lead to additional suppression costs in the future, only further highlighting the need for an ability to evaluate economic tradeoffs in investments across the wildfire management spectrum. Critically, these economic analyses need to accurately capture the complex spatial and stochastic aspects of wildfire, the inherent uncertainty associated with monetizing environmental impacts of wildfire, the costs and effectiveness of alternative management policies, and linkages between pre-fire investments and active incident management. Investing in hazardous fuels reduction and forest restoration in particular is a major policy lever for pre-fire risk mitigation, and will be a primary focus of our presentation. Evaluating alternative fuel management and suppression policies could provide opportunities for significant efficiency improvements in the development of risk-informed management fire management strategies. Better understanding tradeoffs of fire impacts and costs can help inform policy questions such as how much of the landscape to treat and how to balance investments in treating new areas versus maintaining previous investments. We will summarize current data needs, knowledge gaps, and other factors

  3. Radionuclides in the environment: Risks and opportunities

    International Nuclear Information System (INIS)

    Elzerman, A.W.

    1993-01-01

    Environmental chemistry plays a critical role in the open-quotes nuclear ageclose quotes. It makes a vital contribution to understanding of the sources, fate and effects of radionuclides in the environment, both man-made and natural. Risk assessment of radionuclides in the environment relies heavily on the tools of environmental chemistry. On the other hand, radionuclides provide unique opportunities to exploit in environmental chemistry investigations due to their well-defined sources, traceability in environmental processes, analytical sensitivities, and open-quotes built-inclose quotes radioactive decay open-quotes clocksclose quotes. In some cases naturally present radionuclides are utilized, while in others tracers are deliberately added or have already been added by the nuclear fuel cycle or nuclear testing. Several examples in each of these categories are discussed to spotlight the current status of environmental chemistry and radionuclides in the environment as an example application

  4. [Strategies for reducing risks in smoking: opportunity or threat].

    Science.gov (United States)

    Córdoba, Rodrigo; Nerín, Isabel

    2009-12-01

    The smoking control policies recommended by the World Health Organisation have achieved a slight decrease in smoking prevalence in the developed countries, although associated mortality is still very high. The use of tobacco products other than cigarettes and even medicinal nicotine (known as nicotine replacement therapy (NRT)) has been proposed as a risk reduction strategy. Among the tobacco products with less individual risk than cigarettes would be any type of tobacco without smoke (smokeless) with a low content in nitrosamines and modified cigarettes; both forms included under the PREP (Potentially Reduced Exposure Products) concept. The idea would be to promote these products among those who cannot quit smoking or wish to reduce their risk without giving up nicotine intake. The possible effects of risk reduction strategies, including PREP, on the decreased prevalence and morbidity and mortality are reviewed, and the possible implications that this measure could have in our country are analysed. Tobacco control measures in Spain are recent and still insufficient. Therefore, the current priority in Spain is the development of policies of control that have shown to more than effective. The marketing and advertising of new tobacco products, even with reduced potential risk, seems more a serious threat than an opportunity for the development of smoking control policies.

  5. Sustainability of biofuels in Latin America: Risks and opportunities

    Energy Technology Data Exchange (ETDEWEB)

    Janssen, Rainer, E-mail: rainer.janssen@wip-munich.de [WIP Renewable Energies, Sylvensteinstrasse 2, 81369 Munich (Germany); Rutz, Dominik Damian [WIP Renewable Energies, Sylvensteinstrasse 2, 81369 Munich (Germany)

    2011-10-15

    Several Latin American countries are setting up biofuel programmes to establish alternative markets for agricultural commodities. This is mainly triggered by the current success of Brazilian bioethanol production for the domestic market and for export. Furthermore, the global biofuel market is expected to increase due to ambitious biofuel programmes in the EU and in the USA. Colombia, Venezuela, Costa Rica and Guatemala are focusing on bioethanol production from sugarcane whereas biofuel production in Argentina is based on soy biodiesel. Recent developments of the biofuel sector take place extremely rapid especially in Argentina, which became one of the five largest biodiesel producers in the world in 2008. Till date no specific biofuel sustainability certification systems have been implemented in Latin American, as well as on global level. This fact and the predominant use of food crops for biofuel production raise concerns about the sustainability of biofuel production related to environmental and social aspects. This paper provides an overview of the hotspots of conflicts in biofuel production in Latin America. It investigates presently available sustainability tools and initiatives to ensure sustainable biofuel production in Latin America. Finally, it provides an outlook on how to integrate sustainability in the Latin American biofuel sector. - Research Highlights: > This study investigates risks and opportunities of biofuels in Latin America. > Latin American countries are setting up programmes to promote biofuel development. > Strong biofuel sectors provide opportunities for economic development. > Potential negative impact includes deforestation and effects on food security. > Sustainability initiatives exist to minimise negative impact.

  6. Sustainability of biofuels in Latin America: Risks and opportunities

    International Nuclear Information System (INIS)

    Janssen, Rainer; Rutz, Dominik Damian

    2011-01-01

    Several Latin American countries are setting up biofuel programmes to establish alternative markets for agricultural commodities. This is mainly triggered by the current success of Brazilian bioethanol production for the domestic market and for export. Furthermore, the global biofuel market is expected to increase due to ambitious biofuel programmes in the EU and in the USA. Colombia, Venezuela, Costa Rica and Guatemala are focusing on bioethanol production from sugarcane whereas biofuel production in Argentina is based on soy biodiesel. Recent developments of the biofuel sector take place extremely rapid especially in Argentina, which became one of the five largest biodiesel producers in the world in 2008. Till date no specific biofuel sustainability certification systems have been implemented in Latin American, as well as on global level. This fact and the predominant use of food crops for biofuel production raise concerns about the sustainability of biofuel production related to environmental and social aspects. This paper provides an overview of the hotspots of conflicts in biofuel production in Latin America. It investigates presently available sustainability tools and initiatives to ensure sustainable biofuel production in Latin America. Finally, it provides an outlook on how to integrate sustainability in the Latin American biofuel sector. - Research Highlights: → This study investigates risks and opportunities of biofuels in Latin America. → Latin American countries are setting up programmes to promote biofuel development. → Strong biofuel sectors provide opportunities for economic development. → Potential negative impact includes deforestation and effects on food security. → Sustainability initiatives exist to minimise negative impact.

  7. Mastery of risks and operational safety, risks and opportunities

    International Nuclear Information System (INIS)

    2004-01-01

    Creating socially useful richness is certainly the prime reason for companies to exist. Reaching this always moving target leads to seize opportunities and to take risks at the same time. For companies, risks and opportunities are two indissociable factors. Any decision making has to deal with an uncertain environment with random events of technological, economical, biological, human, environmental or natural origin. Because of the fear of uncertainty, risk acts as a brake to initiatives. In front of this problem, companies have to adopt a prevention policy based on a global and systemic approach, by identifying, evaluating, quantifying, sorting, mastering and managing unwanted events and by communicating about the way to treat them. In front of uncertainties, the operational safety, thanks to its methods and tools, supplies an incomparable contribution in the form of an help to any decision made with uncertainties. Operational safety contributes to the evaluation of costs and makes more realistic the economical estimations by taking into account the foreseeable and unforeseeable risks. The mastery of unwanted events, of their stakes and uncertainties, allows companies to carry out their projects in non-determined contexts and in a competitive environment. This colloquium concerns all socio-economical actors: industrialists, investors, decision makers, university and laboratory staffs, etc., who need a better evaluation of risks for a better mastery of their decisions in all sectors of activity. Seventeen papers of this conference, dealing with safety analysis and risk assessment at nuclear facilities and at other energy-related facilities, have been selected for Inis. (J.S.)

  8. Opportunities and Risks in Semiconductor Metrology

    Science.gov (United States)

    Borden, Peter

    2005-09-01

    New metrology opportunities are constantly emerging as the semiconductor industry attempts to meet scaling requirements. The paper summarizes some of the key FEOL and BEOL needs. These must be weighed against a number of considerations to ensure that they are good opportunities for the metrology equipment supplier. The paper discusses some of these considerations.

  9. Risks of Leveraged Products

    NARCIS (Netherlands)

    A. Di Cesare (Antonio)

    2012-01-01

    textabstractLeveraged investments have become a fundamental feature of modern economies. The new financial products allow people to take greater-than-usual exposures to risk factors. This thesis analyzes several different aspects of the risks involved by some frequently used leveraged products:

  10. Chinese M&A,Opportunities & Risks

    Institute of Scientific and Technical Information of China (English)

    Tang Jintao

    2009-01-01

    @@ Recently, the cases of Chinese enterprises' merger and acquisition are emerging in multitude. It is believed that M&A will provide opportunities for China enterprises to go global and act in the global economic environment.

  11. Hibernia production opportunities: A report on business and employment opportunities within the production phase of Hibernia

    International Nuclear Information System (INIS)

    1994-07-01

    The offshore industry in Newfoundland is evolving into a new phase as construction of the Hibernia offshore platform continues and plans are being developed for the operation of the facility to extract oil from deposits on the Grand Banks. A study was conducted to identify the business and employment opportunities available to Newfoundland firms and individuals during Hibernia's production phase. To operate the platform, the Hibernia Management and Development Company (HMDC) and its contractors will employ ca 700-800 people directly. Average annual expenditures will be ca $400 million over the project life of 19 y. Ca 38% of these expenditures represent the operator's own costs, with the rest spent on downhole services, modifications and repairs, logistics and transportation, replacement equipment and materials, and routine maintenance. It is clearly stated that in formulating strategies to pursue production phase opportunities, companies must understand the greenfield characteristics of the Hibernia oil field and the implications that has on the operator's philosophy to procuring goods and services. Paramount to the discussion on procurement is the operator's choice of contracting out and performing services in-house. A number of approaches used by North Sea operators to procure goods and services are reviewed, and a trend is noted toward partnering agreements which are defined as multipurpose, long-term contractual relationships. HMDC is considering entering such agreements. HMDC's employment policies are outlined and business opportunities are described in alphabetical order by sector, giving a description of the opportunity, contracting strategy, and a list of typical companies involved in the sector. 2 figs., 7 tabs

  12. Formal Modeling and Verification of Opportunity-enabled Risk Management

    OpenAIRE

    Aldini, Alessandro; Seigneur, Jean-Marc; Ballester Lafuente, Carlos; Titi, Xavier; Guislain, Jonathan

    2015-01-01

    With the advent of the Bring-Your-Own-Device (BYOD) trend, mobile work is achieving a widespread diffusion that challenges the traditional view of security standard and risk management. A recently proposed model, called opportunity-enabled risk management (OPPRIM), aims at balancing the analysis of the major threats that arise in the BYOD setting with the analysis of the potential increased opportunities emerging in such an environment, by combining mechanisms of risk estimation with trust an...

  13. Productivity improvement opportunities at Navy public works activities

    OpenAIRE

    Dieffenbach, Richard Jacob

    1992-01-01

    Approved for public release; distribution is unlimited This study identifies six principal opportunities for productivity improvement at Navy Public Works in-house maintenance activities: improving work assignment, increasing shop supervisor effectiveness, reducing long lunches and early quits (through understanding of work impediments as demotivational contributors), improving service order management, improving job quality and miscellaneous opportunities. Activity "productivity opportu...

  14. SME's Implementing a Quality Management System- Risks and Opportunities

    Directory of Open Access Journals (Sweden)

    Luise ZEININGER

    2017-12-01

    Full Text Available Part of our daily lives, risk ceased to be just something that managers are desperate to alleviate if not eliminate. It is now rightfully considered a path to explore new opportunities. The last version of the ISO 9001, the 2015 edition, is asking from organization implementing it to determine the risk and opportunities associated with their main processes, the impact over relevant third parties and the context, both internal and external. With this duality as starting point, we have investigated among SME's implementing a quality management system what would they consider to be the risk and opportunities associated to this action. Our paper presents hereinafter the partial results of a wider study on Romanian SME's management, especially the findings related to what managers consider as risk or opportunity when implementing a quality management system.

  15. Risk of energy production

    International Nuclear Information System (INIS)

    Inhaber, Herbert.

    1978-03-01

    Every human activity involves risk of accident or disease. Generation of energy is no exception. Although such risk has been considered for conventional systems (coal, oil and nuclear), a similar analysis for the so-called alternative or non-conventional systems (solar, wind, ocean thermal and methanol) has been lacking. This paper presents an evaluation of the risk, both occupational and to the public, of non-conventional energy systems. They are considered both in absolute terms and in relation to conventional systems. The risk of most non-conventional systems, per unit of energy output, is comparable to, and in some cases much higher than, the risk from coal and oil. This conclusion holds whether we consider deaths or injuries. Nuclear power and natural gas had the lowest overall risk of the ten technologies considered. Ocean thermal energy ranked third. The surprising result is that the other seven technologies considered were found to be up to 100 times less safe. The total risk is calculated by considering six components: material acquisition and construction, emissions caused by material production, operation and maintenance, energy back-up, energy storage, and transportation. In this way the risk of widely different systems can be fairly assessed. This methodology of 'risk accounting' will not tell us which energy technology to use. However, it can be employed to inform society of the risk inherent in competing energy systems. (author)

  16. Big Data and Health Economics: Opportunities, Challenges and Risks

    Directory of Open Access Journals (Sweden)

    Diego Bodas-Sagi

    2018-03-01

    Full Text Available Big Data offers opportunities in many fields. Healthcare is not an exception. In this paper we summarize the possibilities of Big Data and Big Data technologies to offer useful information to policy makers. In a world with tight public budgets and ageing populations we feel necessary to save costs in any production process. The use of outcomes from Big Data could be in the future a way to improve decisions at a lower cost than today. In addition to list the advantages of properly using data and technologies from Big Data, we also show some challenges and risks that analysts could face. We also present an hypothetical example of the use of administrative records with health information both for diagnoses and patients.

  17. China in Mexico: More Opportunity than Risk

    Science.gov (United States)

    2011-10-17

    factory.55 Mexico’s percent of Ford’s U.S. car production went from 11.8 in 2006 to 16 percent in 2008.56 Nissan , Mazda, Volkswagen, Audi, Toyota ... compared to the time lag (and increased cost) of over a week required to transport products from China to the United States. Even in the well...and Honda also produce cars in Mexico, all increasing investment and manufacturing facilities.57 China, in selecting Mexico as a major FDI

  18. LDHI opportunities for offshore European production

    Energy Technology Data Exchange (ETDEWEB)

    Clark, L. W.; Anderson, J.; Frostman, L.; Poynton, N.

    2006-03-15

    Low Dosage Hydrate Inhibitors (LDHIs) are gaining worldwide acceptance as a viable alternative to the more conventional methods of hydrate flow assurance control. Use of this LDHI technology in the European area is becoming more common as operators are beginning to implement and gain from the advantages of LDHIs. This paper will review the basic applicability of the various LDHIs and will review LDHI case histories worldwide in order to show how this technology could be implemented to a greater extent into European production systems. Case histories will illustrate the use and advantages of multifunctional products indicating how operating companies can reduce operating costs and capital expenditure through their implementation. Differing production scenarios will be covered indicating how different LDHIs can be used to cover a range of applications in the field, such as those found in the European region. These will cover both the use of Anti-Agglomerants (AA) and Kinetic Hydrate Inhibitors (KHI). (Author)

  19. Biotechnology for Chemical Production: Challenges and Opportunities.

    Science.gov (United States)

    Burk, Mark J; Van Dien, Stephen

    2016-03-01

    Biotechnology offers a new sustainable approach to manufacturing chemicals, enabling the replacement of petroleum-based raw materials with renewable biobased feedstocks, thereby reducing greenhouse gas (GHG) emissions, toxic byproducts, and the safety risks associated with traditional petrochemical processing. Development of such bioprocesses is enabled by recent advances in genomics, molecular biology, and systems biology, and will continue to accelerate as access to these tools becomes faster and cheaper. Copyright © 2015 Elsevier Ltd. All rights reserved.

  20. The Butterfly House Industry: Conservation Risks and Education Opportunities

    Directory of Open Access Journals (Sweden)

    Michael Boppré

    2012-01-01

    Full Text Available This paper addresses the mass supply and use of butterflies for live exhibits, discusses the risks to biodiversity which this creates, and the educational opportunities it presents. Over the past 30 years a new type of insect zoo has become popular worldwide: the butterfly house. This has given rise to the global Butterfly House Industry (BHI based on the mass production of butterfly pupae as a cash crop. Production is largely carried out by privately-owned butterfly farms in tropical countries, notably Central America and Southeast Asia. Most pupae are exported to North America and Europe, although the number of butterfly houses in tropical countries is growing. The BHI is described with respect to its stakeholders, their diverse interests, and its extent. It is estimated that the global turnover of the BHI is in the order of USD 100 million. From a conservation perspective, there is a tension between risks and benefits. The risks to biodiversity are primarily unsustainable production, potential bastardisation of local faunas and floras, and genetic mixing within and even between butterfly species. This paper discusses general ways of managing these risks. Ethical concerns range from fair trade issues to animal husbandry and the use of wildlife for entertainment. For the risks to biodiversity and unresolved ethical issues to be tolerable, the BHI needs to make a significant contribution to conservation, primarily through effective education about butterfly biology as a means to raise public awareness of basic ecological processes, and conservation and environmental issues. It should also engage with local conservation initiatives. Currently the BHI′s great potential for public good in these respects is rarely realised. The paper concludes by looking at the special nature of the BHI, and its need for effective self-regulation if it is to continue to escape from public scrutiny and the introduction of restrictive regulations. The BHI needs to

  1. Rare earths production and marketing opportunities

    International Nuclear Information System (INIS)

    Falconnet, P.G.

    1988-01-01

    The rare earths (RE) market is relatively small. The total production during 1968 was only 10000 tons (REO) which rose to 27000 tons (REO) during 1985. The three major areas of application, which are volume market for ceric rare earths are catalysts, glass ceramics and metallurgy. Among the other uses of rare earths, the permanent magnets, lamp phosphors and fine ceramics have registered significant growth in RE consumption. Monazite and bastnasite are the main natural source for rare earths and processing of these for one of the rare earths in high demand leads to over production of some others not in demand, thus creating a balance problem. The growth in RE market has always been influenced by the technology shifts and product substitution. For example, the RE consumption during 1974/76 for desulfurization of steel had substantially decreased due to the usage of calcium. Similarly, 1985 had witnessed a drastic cut in the use of REs in fluid cracking due to the introduction of stabilized zeolites which contain less REO. Thus, the overall compound growth rate of demand was only 3.9 % per year during the period 1970-1985. At present, 37 % of the rare earths production goes to the glass/ceramics industry, 33 % for catalyst and 25 % to metallurgy. The price of REs constantly shows a downward trend. This trend coupled with the rapid changes taking place in the various technological fields, demands greater flexibility and high marketing skills from the RE producers. The key factor for future expansion of RE market will be the development of 'high volume' application of ceric rare earths. (author) 2 figs., 8 tabs

  2. Rapport: The Value for Money Discourse: Risks and Opportunities ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    optimisation des ressources exerce également une influence croissante sur ce qui revêt de l'importance pour les bailleurs de fonds. Le rapport The Value for Money Discourse: Risks and Opportunities for R4D a pour but de ...

  3. Processing Challenges and Opportunities of Camel Dairy Products

    DEFF Research Database (Denmark)

    Berhe, Tesfemariam; Seifu, Eyassu; Ipsen, Richard

    2017-01-01

    A review on the challenges and opportunities of processing camel milk into dairy products is provided with an objective of exploring the challenges of processing and assessing the opportunities for developing functional products from camel milk. The gross composition of camel milk is similar...... to bovine milk. Nonetheless, the relative composition, distribution, and the molecular structure of the milk components are reported to be different. Consequently, manufacturing of camel dairy products such as cheese, yoghurt, or butter using the same technology as for dairy products from bovine milk can...... result in processing difficulties and products of inferior quality. However, scientific evidence points to the possibility of transforming camel milk into products by optimization of the processing parameters. Additionally, camel milk has traditionally been used for its medicinal values and recent...

  4. Consumer behaviour and opportunities for new product development

    DEFF Research Database (Denmark)

    Grunert, Klaus G

    and Q-PORKCHAINS and a Danish project, all dealing with new product development in the meat sector, it is shown how the use of consumer insight techniques can a) support the identification of market opportunities, b) make sure that technologies applied are acceptable to consumers, c) aid the selection...

  5. Molecular genetics and livestock selection. Approaches, opportunities and risks

    International Nuclear Information System (INIS)

    Williams, J.L.

    2005-01-01

    Following domestication, livestock were selected both naturally through adaptation to their environments and by man so that they would fulfil a particular use. As selection methods have become more sophisticated, rapid progress has been made in improving those traits that are easily measured. However, selection has also resulted in decreased diversity. In some cases, improved breeds have replaced local breeds, risking the loss of important survival traits. The advent of molecular genetics provides the opportunity to identify the genes that control particular traits by a gene mapping approach. However, as with selection, the early mapping studies focused on traits that are easy to measure. Where molecular genetics can play a valuable role in livestock production is by providing the means to select effectively for traits that are difficult to measure. Identifying the genes underpinning particular traits requires a population in which these traits are segregating. Fortunately, several experimental populations have been created that have allowed a wide range of traits to be studied. Gene mapping work in these populations has shown that the role of particular genes in controlling variation in a given trait can depend on the genetic background. A second finding is that the most favourable alleles for a trait may in fact. be present in animals that perform poorly for the trait. In the long term, knowledge of -the genes controlling particular traits, and the way they interact with the genetic background, will allow introgression between breeds and the assembly of genotypes that are best suited to particular environments, producing animals with the desired characteristics. If used wisely, this approach will maintain genetic diversity while improving performance over a wide range of desired traits. (author)

  6. Biorefinery of microalgae - opportunities and constraints for different production scenarios.

    Science.gov (United States)

    Hariskos, Ioanna; Posten, Clemens

    2014-06-01

    In order to design economically feasible production processes it is necessary, as part of the biorefinery concept, to valorize all constituents of the microalgal biomass. Such an approach requires appropriate biorefinery side-process strategies to be adapted to production of the primary product. These strategies are particularly valid for microalgae, since the composition and amount of residual biomass can vary significantly depending on cell stoichiometry and cultivation techniques. This review investigates opportunities and constraints for biorefinery concepts in production scenarios for four different products from microalgae with different market volumes, including high- and medium-value products, whole cells and biodiesel. Approaches to close material and energy balances, as well as to adapt the biorefinery according to biological potential, process routes, and market needs are presented, which will further contribute to making the biorefinery concept a success. Copyright © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  7. HCl co-production from CFC alternatives: Threat or opportunity?

    International Nuclear Information System (INIS)

    Mikulka, C.J.

    1990-01-01

    CFC production facilities have typically been located near CFC consumers and not necessarily near their feedstock sources. The co-production of HCl from these facilities has in the past been small and manageable by the CFC producers. Production of the CFC replacements, however, will result in larger quantities of HCl co-production at a scrutiny. Since new facilities are likely to be required for the replacements, there may be the opportunity to site facilities next to chlorocarbon suppliers who may be in a better position to take back the HCl co-product for reuse in their production facilities. This paper provides an overview of these issues as well as considers the implications of returning the HCl to the chlorocarbon supplier as well as viability of converting HCl back to chlorine

  8. Processing Challenges and Opportunities of Camel Dairy Products

    Directory of Open Access Journals (Sweden)

    Tesfemariam Berhe

    2017-01-01

    Full Text Available A review on the challenges and opportunities of processing camel milk into dairy products is provided with an objective of exploring the challenges of processing and assessing the opportunities for developing functional products from camel milk. The gross composition of camel milk is similar to bovine milk. Nonetheless, the relative composition, distribution, and the molecular structure of the milk components are reported to be different. Consequently, manufacturing of camel dairy products such as cheese, yoghurt, or butter using the same technology as for dairy products from bovine milk can result in processing difficulties and products of inferior quality. However, scientific evidence points to the possibility of transforming camel milk into products by optimization of the processing parameters. Additionally, camel milk has traditionally been used for its medicinal values and recent scientific studies confirm that it is a rich source of bioactive, antimicrobial, and antioxidant substances. The current literature concerning product design and functional potential of camel milk is fragmented in terms of time, place, and depth of the research. Therefore, it is essential to understand the fundamental features of camel milk and initiate detailed multidisciplinary research to fully explore and utilize its functional and technological properties.

  9. Perception of Product Risks

    NARCIS (Netherlands)

    Fischer, A.R.H.

    2017-01-01

    This chapter provides several explanations for consumer risk perception. For frequently repeated behavior that is seemingly under their own control, consumers tend to be overly optimistic. This occurs in spite of the general tendency of consumers to be risk averse. Specific dimensions of different

  10. Energy conservation opportunities: audit vis-a-vis mine productivity

    Energy Technology Data Exchange (ETDEWEB)

    Iyer, G.H.

    2009-07-01

    Mining operation, whether opencast or underground, with modern equipment is highly energy intensive, needing energy conservation and management to ensure efficiency, cost effectiveness, and overall productivity. Exhaustible primary energy resources such as coal, lignite, oil, and nuclear fuels are being mined out to meet our energy needs. An attempt has been made in this paper to highlight the energy conservation opportunities, energy audit, the relevant Energy Conservation Act 2001 and certain energy saving measures leading to higher productivity followed by a few case study examples. 3 refs.

  11. Opportunities application of cleaner production practices in paint industry

    International Nuclear Information System (INIS)

    Mohammed, Y. S. Y.

    2010-08-01

    There are releases of volatile organic compounds VOC from paint manufacturing process steps and from cleaning operations in El Mohandas Paint Factory. These emission can cause health, safety and productivity problems in the work area. Hence cleaner production application is necessary in this case. Some of the manufacturing processes and equipment used to accomplish these manufacturing are analyzed and generate cleaner production opportunities, implement some of cleaner production solutions of VOC emission control by some of the methods used by paint facilities in reducing emissions. It was found that there is no control available for emissions factors in paints manufacturing process, so that VOC emission based on raw material consumption rather than calculation emission from processes or equipment by alternative method. (Author)

  12. Future opportunities in production of disposable optics and electronics

    Science.gov (United States)

    Korhonen, Raimo

    2001-05-01

    The several production methods of paper processing chain can be used, by analogy, to generate novel ideas for production of optics and electronics. Paper processing is a very fast reel-to-reel process: In the beginning of the paper web production the process is running at the speed of over thousand meters per minute and the web width can be 10 meters, and still at the later stages the speed is several hundreds of meters per minute with the web width of a couple of meters. There are several potential reel-to-reel production methods like embossing, printing, laminating and different kinds of vacuum coating, for example evaporation and sputtering. End products are complex multi-layer composite structures. The benefits from this analogy for optics and electronics would be ideas for ultra fast production, paper-like disposable and recyclable products and the integration of optics and electronics into ordinary things like books, wallpapers, tissue papers and packages. Two experiments are presented to demonstrate the possibilities. In the first experiment optical patterns are embossed directly on paper. In the second one conductive polymers are printed on paper and plastic webs. In future, a wide network of cooperation will be needed to realize all the opportunities.

  13. Fuel cells and electricity companies - new risk management opportunities

    International Nuclear Information System (INIS)

    Whale, M.

    2004-01-01

    'Full text:' Deregulation, distributed generation, combined heat and power, renewables, fuel cells, hydrogen. Power companies are facing a rapidly evolving environment that is testing their ability to effectively deploy capital and earn profits. While recent deregulation trends have shifted the structure of power markets into separating generators from distributors, the improving economic value proposition offered by smaller scale distributed generation technologies - such as fuel cells - would seem to be a conflicting development. In this complex and changing environment, decisions based on the economic reality of the capital markets are likely to prevail. By examining the opportunity to enhance risk management offered by stationary fuel cells, particularly in CHP applications, we provide a context for the issues being discussed in today's sessions focusing on power companies and electric utilities. Our risk management perspective suggests a pathway for implementing fuel cells in combined heat and power applications that large power generators can introduce in increasingly smaller sizes. With capital costs of fuel cells high and risk tolerance of power companies low, the challenge for smaller technology developers will be to reduce the apparently long time horizon that persists for substantial deployment. (author)

  14. Social Media in Surgical Training: Opportunities and Risks.

    Science.gov (United States)

    Ovaere, Sander; Zimmerman, David D E; Brady, Richard R

    2018-05-02

    Surgeon engagement with social media is growing rapidly. Innovative applications in diverse fields of health care are increasingly available. The aim of this review is to explore the current and future applications of social media in surgical training. In addition, risks and barriers of social media engagement are analyzed, and recommendations for professional social media use amongst trainers and trainees are suggested. The published, peer-reviewed literature on social media in medicine, surgery and surgical training was reviewed. MESH terms including "social media", "education", "surgical training" and "web applications" were used. Different social media surgical applications are already widely available but limited in use in the trainee's curriculum. E-learning modalities, podcasts, live surgery platforms and microblogs are used for teaching purposes. Social media enables global research collaboratives and can play a role in patient recruitment for clinical trials. The growing importance of networking is emphasized by the increased use of LinkedIn, Facebook, Sermo and other networking platforms. Risks of social media use, such as lack of peer review and the lack of source confirmation, must be considered. Governing surgeon's and trainee's associations should consider adopting and sharing their guidelines for standards of social media use. Surgical training is changing rapidly and as such, social media presents tremendous opportunities for teaching, training, research and networking. Awareness must be raised on the risks of social media use. Copyright © 2018 Association of Program Directors in Surgery. All rights reserved.

  15. Risks and opportunities of virtual learning: the experience of UOC

    Directory of Open Access Journals (Sweden)

    Adela Ros Híjar

    2001-06-01

    Full Text Available In this article, I have tried to give answers to the question of what the risks and opportunities of virtual learning are. In this sense, the UOC's experience has been of great value to analyse several key issues such as the new ways of accessing quality education, the new ways of participation, the new values of educational processes as well as some of the structural factors on which e-learning is based, but which place its very model in jeopardy. Direct observation of some key processes as well as contact with the main actors (e.g. students, teachers and technicians have provided valuable information about some factors to consider when analysing the social implications of virtual learning.

  16. Agent of opportunity risk mitigation: people, engineering, and security efficacy.

    Science.gov (United States)

    Graham, Margaret E; Tunik, Michael G; Farmer, Brenna M; Bendzans, Carly; McCrillis, Aileen M; Nelson, Lewis S; Portelli, Ian; Smith, Silas; Goldberg, Judith D; Zhang, Meng; Rosenberg, Sheldon D; Goldfrank, Lewis R

    2010-12-01

    Agents of opportunity (AO) are potentially harmful biological, chemical, radiological, and pharmaceutical substances commonly used for health care delivery and research. AOs are present in all academic medical centers (AMC), creating vulnerability in the health care sector; AO attributes and dissemination methods likely predict risk; and AMCs are inadequately secured against a purposeful AO dissemination, with limited budgets and competing priorities. We explored health care workers' perceptions of AMC security and the impact of those perceptions on AO risk. Qualitative methods (survey, interviews, and workshops) were used to collect opinions from staff working in a medical school and 4 AMC-affiliated hospitals concerning AOs and the risk to hospital infrastructure associated with their uncontrolled presence. Secondary to this goal, staff perception concerning security, or opinions about security behaviors of others, were extracted, analyzed, and grouped into themes. We provide a framework for depicting the interaction of staff behavior and access control engineering, including the tendency of staff to "defeat" inconvenient access controls. In addition, 8 security themes emerged: staff security behavior is a significant source of AO risk; the wide range of opinions about "open" front-door policies among AMC staff illustrates a disparity of perceptions about the need for security; interviewees expressed profound skepticism concerning the effectiveness of front-door access controls; an AO risk assessment requires reconsideration of the security levels historically assigned to areas such as the loading dock and central distribution sites, where many AOs are delivered and may remain unattended for substantial periods of time; researchers' view of AMC security is influenced by the ongoing debate within the scientific community about the wisdom of engaging in bioterrorism research; there was no agreement about which areas of the AMC should be subject to stronger access

  17. Options for electricity production, the actual opportunities and regulatory framework

    International Nuclear Information System (INIS)

    Raphals, P.

    2006-01-01

    Thermal power and nuclear power represent the traditional methods of generating electricity. This paper presented opportunities for alternative centralized power production methods that include wind energy, biomass and solar energy. It also discussed decentralized alternatives for power generation, such as geothermal energy and cogeneration, including microturbines. The primary focus was on aspects of competitive market design for residential and small commercial applications as well as commercial and industrial applications. Law 116 of Quebec's Energy Board was reviewed in terms of energy policy and utility regulation. In particular, the framework agreement between Hydro-Quebec Production (HQP) and Hydro-Quebec Distribution (HQD) was discussed with reference to balancing electricity produced from renewable energy sources and energy security. The presentation also addressed issues regarding the role of competition, regulation and environmental implications of electricity trade. refs., tabs., figs

  18. The path to Agenda 2020: Progress, products, and opportunities

    International Nuclear Information System (INIS)

    Robinson, V.; McQueen, S.; Dove, L.

    1999-01-01

    To compete in global markets, the forest products industry must reduce its energy use and capital costs, while increasing its productivity and product quality. The industry must also meet strict environmental regulations governing its processing operations. The Industries of the Future initiative offers US industries like the forest products industry an opportunity to develop and implement innovative technical solutions to meet these various challenges. This paper discusses the basic features of the initiative and describes progress in developing three promising technologies: (1) On-Site, On-Demand Chlorine Dioxide Generation, (2) the Methane DeNOsx Reburner and (3) Multiport Cylinder Dryers. The technologies are expected to have near term positive impacts on the forest products industry's energy efficiency and environmental performance. Moreover, the new technologies may be transferable to other manufacturing sectors where they will have similar advantages. The Industries of the Future initiative, facilitated by the US Department of Energy's Office of Industrial Technologies, encourages energy efficiency and environmental protection nationwide

  19. Climate Variability and Change in Bihar, India: Challenges and Opportunities for Sustainable Crop Production

    Directory of Open Access Journals (Sweden)

    Kindie Tesfaye

    2017-11-01

    Full Text Available Climate change and associated uncertainties have serious direct and indirect consequences for crop production and food security in agriculture-based developing regions. Long-term climate data analysis can identify climate risks and anticipate new ones for planning appropriate adaptation and mitigation options. The aim of this study was to identify near-term (2030 and mid-term (2050 climate risks and/or opportunities in the state of Bihar, one of India’s most populous and poorest states, using weather data for 30 years (1980–2009 as a baseline. Rainfall, maximum and minimum temperatures, and evapotranspiration will all increase in the near- and mid-term periods relative to the baseline period, with the magnitude of the change varying with time, season and location within the state. Bihar’s major climate risks for crop production will be heat stress due to increasing minimum temperatures in the rabi (winter season and high minimum and maximum temperatures in the spring season; and intense rainfall and longer dry spells in the kharif (monsoon season. The increase in annual and seasonal rainfall amounts, and extended crop growing period in the kharif season generally provide opportunities; but increasing temperature across the state will have considerable negative consequences on (staple crops by affecting crop phenology, physiology and plant-water relations. The study helps develop site-specific adaptation and mitigation options that minimize the negative effects of climate change while maximizing the opportunities.

  20. Scorched earth: will environmental risks in China overwhelm its opportunities?

    Science.gov (United States)

    Economy, Elizabeth; Lieberthal, Kenneth

    2007-06-01

    Of all the risks of doing business in China, the greatest is the threat posed by environmental degradation. And yet it's barely discussed in corporate boardrooms. This is a serious mistake. Multinationals may be more concerned with intellectual property rights violations, corruption, and potential political instability, but the Chinese government, NGOs, and the Chinese press have been focused squarely on the country's energy shortages, soil erosion, lack of water, and pollution problems, which are so severe they might constrain GDP growth. What's more, the Chinese expect the international community to take the lead in environmental protection. If that doesn't happen, multinationals face clear risks to their operations, their workers' health, and their reputations. In factoring environmental issues into their China strategies, foreign firms need to be both defensive, taking steps to reduce harm, and proactive, investing in environmental protection efforts. Coca-Cola, for example, installed state-of-the-art bottling plants in China that operate with no net loss of water resources. Mattel increased the safety of its Barbie-manufacturing process to protect workers' health. With its efforts to reduce greenhouse gas emissions, GE is shrinking its environmental footprint in China; more proactively, GE is working closely with the Chinese government and scientists to develop clean coal, water purification, and water reuse technologies. In considering the value of such efforts, companies can not only factor in reduced risk but also increased opportunity, as they use innovations designed for the Chinese market in the rest of the world. The bottom line: How well multinationals address environmental issues in China will affect their fortunes in one of the most important economies in the world.

  1. The opportunity-threat theory of decision-making under risk

    OpenAIRE

    Mohan Pandey

    2018-01-01

    A new theory of decision-making under risk, the Opportunity-Threat Theory is proposed. Analysis of risk into opportunity and threat components allows description of behavior as a combination of opportunity seeking and threat aversion. Expected utility is a special case of this model. The final evaluation is an integration of the impacts of opportunity and threat with this expectation. The model can account for basic results as well as several ``new paradoxes'' that refuted c...

  2. Assessment of herbal medicinal products: Challenges, and opportunities to increase the knowledge base for safety assessment

    International Nuclear Information System (INIS)

    Jordan, Scott A.; Cunningham, David G.; Marles, Robin J.

    2010-01-01

    Although herbal medicinal products (HMP) have been perceived by the public as relatively low risk, there has been more recognition of the potential risks associated with this type of product as the use of HMPs increases. Potential harm can occur via inherent toxicity of herbs, as well as from contamination, adulteration, plant misidentification, and interactions with other herbal products or pharmaceutical drugs. Regulatory safety assessment for HMPs relies on both the assessment of cases of adverse reactions and the review of published toxicity information. However, the conduct of such an integrated investigation has many challenges in terms of the quantity and quality of information. Adverse reactions are under-reported, product quality may be less than ideal, herbs have a complex composition and there is lack of information on the toxicity of medicinal herbs or their constituents. Nevertheless, opportunities exist to capitalise on newer information to increase the current body of scientific evidence. Novel sources of information are reviewed, such as the use of poison control data to augment adverse reaction information from national pharmacovigilance databases, and the use of more recent toxicological assessment techniques such as predictive toxicology and omics. The integration of all available information can reduce the uncertainty in decision making with respect to herbal medicinal products. The example of Aristolochia and aristolochic acids is used to highlight the challenges related to safety assessment, and the opportunities that exist to more accurately elucidate the toxicity of herbal medicines.

  3. Private Animal Welfare Standards-Opportunities and Risks.

    Science.gov (United States)

    Lundmark, Frida; Berg, Charlotte; Röcklinsberg, Helena

    2018-01-02

    The current shift moves the governance of animal welfare away from the government towards the private market and the consumers. We have studied the intentions, content, and on-farm inspection results from different sets of animal welfare legislation and private standards with an aim to highlight the most important opportunities and risks identified in relation to the trend of increasingly relying on private standards for safeguarding or improving farm animal welfare. Our results show that different focuses, intentions, animal welfare requirements, inspection methods (i.e., methods for measuring and evaluating the compliance with a regulation), and inspection results, together with the use of vague wordings and a drive towards more flexible regulations does certainly not facilitate the interpretation and implementation of animal welfare regulations, especially not in relation to each other. Since farmers today often have to comply with several animal welfare regulations, including private standards, it is important to stress that a given regulation should never be seen as a single, stand-alone phenomenon, and the policymakers must hence consider the bigger picture, and apply the standards in relation to other existing regulations. This is especially relevant in relation to the legislation, a level that a private standard can never ignore.

  4. Cross-Strait Economic Relations: Opportunities Outweigh Risks

    National Research Council Canada - National Science Library

    Roy, Denny

    2004-01-01

    ...." Taiwan finds the economic opportunities on the mainland irresistible. Yet Taiwan recognizes that trading with China supports the strategy of the country representing Taiwan's chief security threat...

  5. Private Animal Welfare Standards—Opportunities and Risks

    Science.gov (United States)

    Röcklinsberg, Helena

    2018-01-01

    Simple Summary In all European countries, farmers keeping animals must comply with European and national animal welfare legislation. Each government has a responsibility to make sure that the legislation is complied with by the farmers. However, during the last decades it has become increasingly common that private organisations, such as the industry, farmers’ organisations, or animal welfare organisations, develop additional animal welfare regulations (‘private standards’) that the farmers also need to comply with. These private standards have the opportunity to improve animal welfare above the legislative level, however, in our study we have shown that this is not always the case and that all of these different private standards, in addition to the legislation, makes it difficult to get an overview of the animal welfare regulation and control arena. For the sake of the farmers, the animal welfare inspectors, the consumers, and the animals we conclude that it is important that policymakers consider this arena as a whole and not their own regulation as a single phenomenon. Abstract The current shift moves the governance of animal welfare away from the government towards the private market and the consumers. We have studied the intentions, content, and on-farm inspection results from different sets of animal welfare legislation and private standards with an aim to highlight the most important opportunities and risks identified in relation to the trend of increasingly relying on private standards for safeguarding or improving farm animal welfare. Our results show that different focuses, intentions, animal welfare requirements, inspection methods (i.e., methods for measuring and evaluating the compliance with a regulation), and inspection results, together with the use of vague wordings and a drive towards more flexible regulations does certainly not facilitate the interpretation and implementation of animal welfare regulations, especially not in relation to

  6. Scientific Opportunities to Reduce Risk in Nuclear Process Science

    International Nuclear Information System (INIS)

    Bredt, Paul R.; Felmy, Andrew R.; Gauglitz, Phillip A.; Poloski, Adam P.; Vienna, John D.; Moyer, Bruce A.; Hobbs, David; Wilmarth, B.; Mcilwain, Michael; Subramanian, K.; Krahn, Steve; Machara, N.

    2009-01-01

    overall intent of this paper is to foster a dialogue on how basic scientific research can assist DOE in executing its cleanup and environmental management mission. In this paper, we propose that such scientific investments not be focused solely on what may be viewed as current DOE needs, but also be based upon longer-term investments in specific areas of science that underpin technologies presently in use. In the latter regard, we propose four science theme areas: (1) the structure and dynamics of materials and interfaces, (2) coupled chemical and physical processes, (3) complex solution phase phenomena, and (4) chemical recognition phenomena. The proposed scientific focus for each of these theme areas and the scientific opportunities are identified, along with links to major risks within the initiative areas identified in EM's Engineering and Technology Roadmap.

  7. Nanopesticides and nanofertilizers: emerging contaminants or opportunities for risk mitigation?

    Directory of Open Access Journals (Sweden)

    Melanie eKah

    2015-11-01

    Full Text Available Research into nanotechnology applications for use in agriculture has become increasingly popular over the past decade, with a particular interest in developing novel nanoagrochemicals in the form of so-called nanopesticides and nanofertilizers. In view of the extensive body of scientific literature available on the topic, many authors have foreseen a revolution in current agricultural practices.This perspective integrates scientific, regulatory, public and commercial viewpoints, and aims at critically evaluating progress made over the last decade. A number of key (and sometimes controversial questions are addressed with the aim of identifying the products that will soon emerge on the market and analyzing how they can fit into current regulatory and commercial frameworks. Issues related to the differences in definitions and perceptions within different sectors are discussed, as well as our current ability to assess new risks and benefits relative to conventional products. Many nanoagrochemicals resemble products used currently, which raises the question whether the effect of formulation has been sufficiently taken into account when evaluating agrochemicals. This analysis identifies directions for future research and regulatory needs in order to encourage intelligent design and promote the development of more sustainable agrochemicals.

  8. From Risk to Opportunity. How Insurers Can Proactively and Profitably Manage Climate Change

    International Nuclear Information System (INIS)

    Mills, E.; Lecomte, E.

    2006-08-01

    Last year's USD 45 billion of insured losses from Hurricane Katrina was only the latest reminder of why investors and consumers are concerned about the impacts of climate change on the insurance industry. Twelve months after the devastating storm hit New Orleans, insurers and their shareholders are still feeling the ripples. Record insured losses, rating downgrades, coverage pullbacks and class-action lawsuits are just a few of the reverberations that have been felt across the industry. Meanwhile, consumers are feeling the combined sting of price shocks and reduced availability. So serious is the issue that 20 leading investors, representing over $800 billion in assets, called on the nation's largest insurance companies to disclose their financial exposure from climate change and steps they are taking to reduce those financial impacts. But, while most of the attention is focused on the growing risks, climate change also creates vast business opportunities to be part of the solution to global warming. Just as the industry has historically asserted its leadership to minimize risks from building fires and earthquakes, insurers have a huge opportunity today to develop creative loss-prevention products and services that will reduce climate-related losses for consumers, governments and insurers, while trimming the emissions causing global warming. This report focuses on the encouraging progress made by insurers to develop these new products and services. It identifies more than 190 concrete examples available, or soon-to-be-available, from dozens of insurance providers in 16 countries. In addition to benefiting insurers' core business and investment activities, these programs afford insurers the opportunity to differentiate their products from their competitors, while also enhancing their reputation with customers who are increasingly looking for all sectors of the industry to come forward with effective responses to the threats caused by climate change. More than half

  9. Risk management in product innovation projects

    NARCIS (Netherlands)

    Halman, J.I.M.; Keizer, J.A.

    1993-01-01

    In product innovation projects risk management has become increasingly important. Technological and commercial developments ask for effective and efficient product innovation. Systematic diagnosing and management of risks can help to make product innovation projects successful. In this paper a

  10. Nanotechnology in agriculture: Opportunities, toxicological implications, and occupational risks.

    Science.gov (United States)

    Iavicoli, Ivo; Leso, Veruscka; Beezhold, Donald H; Shvedova, Anna A

    2017-08-15

    Nanotechnology has the potential to make a beneficial impact on several agricultural, forestry, and environmental challenges, such as urbanization, energy constraints, and sustainable use of resources. However, new environmental and human health hazards may emerge from nano-enhanced applications. This raises concerns for agricultural workers who may become primarily exposed to such xenobiotics during their job tasks. The aim of this review is to discuss promising solutions that nanotechnology may provide in agricultural activities, with a specific focus on critical aspects, challenging issues, and research needs for occupational risk assessment and management in this emerging field. Eco-toxicological aspects were not the focus of the review. Nano-fertilizers, (nano-sized nutrients, nano-coated fertilizers, or engineered metal-oxide or carbon-based nanomaterials per se), and nano-pesticides, (nano-formulations of traditional active ingredients or inorganic nanomaterials), may provide a targeted/controlled release of agrochemicals, aimed to obtain their fullest biological efficacy without over-dosage. Nano-sensors and nano-remediation methods may detect and remove environmental contaminants. However, limited knowledge concerning nanomaterial biosafety, adverse effects, fate, and acquired biological reactivity once dispersed into the environment, requires further scientific efforts to assess possible nano-agricultural risks. In this perspective, toxicological research should be aimed to define nanomaterial hazards and levels of exposure along the life-cycle of nano-enabled products, and to assess those physico-chemical features affecting nanomaterial toxicity, possible interactions with agro-system co-formulants, and stressors. Overall, this review highlights the importance to define adequate risk management strategies for workers, occupational safety practices and policies, as well as to develop a responsible regulatory consensus on nanotechnology in agriculture

  11. Scientific Opportunities to Reduce Risk in Nuclear Process Science

    International Nuclear Information System (INIS)

    Bredt, P.R.; Felmy, A.R.; Gauglitz, P.A.; Poloski, A.P.; Vienna, J.D.; Moyer, B.A.; Hobbs, D.; Wilmarth, B.; McIlwain, M.; Subramanian, K.; Krahn, S.; Machara, N.

    2009-01-01

    intent of this paper is to foster a dialogue on how basic scientific research can assist DOE in executing its cleanup and environmental management mission. In this document, we propose that such scientific investments should not be focused solely on what may be viewed as current DOE needs, but also upon longer-term investments in specific areas of science that underpin technologies presently in use. In the latter regard, we propose four science theme areas: 1) the structure and dynamics of materials and interfaces, 2) coupled chemical and physical processes, 3) complex solution phase phenomena, and 4) chemical recognition phenomena. The proposed scientific focus for each of these theme areas and the scientific opportunities are identified, along with links to major risks within the initiative areas identified in EM's Engineering and Technology Road-map. The authors encourage feedback from our colleagues in the nuclear waste and related fields. (authors)

  12. Analysis of benefits, opportunities, costs, and risks (BOCR) with the AHP+ANP : A critical validation

    NARCIS (Netherlands)

    Wijnmalen, D.J.D.

    2007-01-01

    This paper shows that the usual multiplicative synthesis of alternative priorities for benefits, opportunities, costs and risks, obtained from separate Analytic Hierarchy or Network models, can be ambiguous. The ratio of benefit and opportunity priorities to cost and risk priorities can be

  13. Opportunities, perspectives and limits in lactic acid production from waste and industrial by-products

    Directory of Open Access Journals (Sweden)

    Mladenović Dragana D.

    2016-01-01

    Full Text Available In line with the goals of sustainable development and environmental protection today great attention is directed towards new technologies for waste and industrial by-products utilization. Waste products represent potentially good raw material for production other valuable products, such as bioethanol, biogas, biodiesel, organic acids, enzymes, microbial biomass, etc. Since the first industrial production to the present, lactic acid has found wide application in food, cosmetic, pharmaceutical and chemical industries. In recent years, the demand for lactic acid has been increasing considerably owing to its potential use as a monomer for the production of poly-lactic acid (PLA polymers which are biodegradable and biocompatible with wide applications. Waste and industrial by-products such are whey, molasses, stillage, waste starch and lignocellulosic materials are a good source of fermentable sugars and many other substances of great importance for the growth of microorganisms, such as proteins, minerals and vitamins. Utilization of waste products for production of lactic acid could help to reduce the total cost of lactic acid production and except the economic viability of the process offers a solution of their disposal. Fermentation process depends on chemical and physical nature of feedstocks and the lactic acid producer. This review describes the characteristics, abilities and limits of microorganisms involved in lactic acid production, as well as the characteristics and types of waste products for lactic acid production. The fermentation methods that have been recently reported to improve lactic acid production are summarized and compared. In order to improve processes and productivity, fed-batch fermentation, fermentation with immobilized cell systems and mixed cultures and opportunities of open (non-sterilized fermentation have been investigated.

  14. IPRs in biobanking- risks and opportunities for translational research

    DEFF Research Database (Denmark)

    Minssen, Timo; Verlinden, Michiel; Huys, Isabelle

    2015-01-01

    The gradual shift from traditional closed innovation systems to more “open” and “transparent” innovation models, rapid technological advances and bio-pharmaceutical innovation gaps have highlighted the importance of an effective governance and use of biobanks. This raises important legal questions...... such as how to deal with intellectual property rights (‘IPRs’) that might arise out of the collection and use of samples and data in research. Only a few projects highlighted the opportunities and potential benefits of user-generated solutions and proper governance of IPRs. This paper aims to provide...... an overview and analysis of the most relevant IPRs in biobanking and to discuss the challenges and opportunities associated with an effective use of biobanks in translational research and innovation. Section 1 specifies challenges in finding a balance between an open and a close collaboration model. Section 2...

  15. Panel data nonparametric estimation of production risk and risk preferences

    DEFF Research Database (Denmark)

    Czekaj, Tomasz Gerard; Henningsen, Arne

    approaches for obtaining firm-specific measures of risk attitudes. We found that Polish dairy farmers are risk averse regarding production risk and price uncertainty. According to our results, Polish dairy farmers perceive the production risk as being more significant than the risk related to output price......We apply nonparametric panel data kernel regression to investigate production risk, out-put price uncertainty, and risk attitudes of Polish dairy farms based on a firm-level unbalanced panel data set that covers the period 2004–2010. We compare different model specifications and different...

  16. Accountability in an information age : opportunities and risks for records management

    NARCIS (Netherlands)

    Meijer, A.J.

    2001-01-01

    Electronic records of government organizations are becoming increasingly important for accountability. Managing electronic records, however, proves to be difficult since information and communication technologies confront organizations with various opportunities and risks. In this paper the findings

  17. Market Opportunities for Cellulose Products From Combined Renewable Resources

    Science.gov (United States)

    Zihare, Lauma; Blumberga, Dagnija

    2017-05-01

    This study investigates available resources that has not been used or is used with low added value, such as woody crops, forest residues and invasive species possibilities in case of cellulosic products. Main aspect is this study is market outlook, to see if the products can have positive market sales if produced. Resource have been selected by availability and current usage and properties they contain. Products have been chosen the most basic, to see is there possibility to enter an existing cellulose product markets. GE/McKinsey matrix have been used for clear visual decision making. The results show that only two out of seven products has a potential in international market.

  18. Current Situation and Development Opportunities of Apple Production inThe Province Konya

    OpenAIRE

    BAYRAMOĞLU, Zeki; ÇELİK, Yusuf; OĞUZ, Cennet

    2009-01-01

    In this study sectoral analysis of apple production activity in Konya was made. Within this scope at first apple production amount in Turkey and in the world and developments in cultivation areas were examined, development opportunities of apple production in the province were discussed. The data about this issue was collected from secondary sources (Food and Agriculture Organization, Turkish Statistical Institute etc.) In line with this data strong, weak sides of this sector, opportunities a...

  19. Leveraging Enterprise Risk Management: Opportunity for Greater Relevance

    Science.gov (United States)

    Abraham, Janice M.; Baird, Robert; Neugebauer, Frank

    2013-01-01

    Enterprise Risk Management (ERM) gained a foothold in higher education during the first decade of the 21st century. College and university governing board members came to their board service with the perspective and experience of having served on corporate boards and in corporate leadership positions where ERM was in active use. Trustees asked…

  20. Processing Challenges and Opportunities of Camel Dairy Products

    DEFF Research Database (Denmark)

    Berhe, Tesfemariam; Seifu, Eyassu; Ipsen, Richard

    2017-01-01

    to bovine milk. Nonetheless, the relative composition, distribution, and the molecular structure of the milk components are reported to be different. Consequently, manufacturing of camel dairy products such as cheese, yoghurt, or butter using the same technology as for dairy products from bovine milk can...

  1. Identifying and Researching Market Opportunities for New High Technology Products.

    Science.gov (United States)

    Dunstan, Peter

    Using a product called the synchro-pulse welder as a case study example, this paper discusses the activities of CSIRO (Commonwealth Scientific and Industrial Research Organisation) in identifying and marketing new high-technology products. A general discussion of CSIRO's market research plans includes two goals to be attained within the next 5…

  2. Opportunity parameters in the development of Product/Service-Systems

    DEFF Research Database (Denmark)

    Matzen, Detlef; Andreasen, Mogens Myrup

    2006-01-01

    In the light of the current focus on innovative business development throughout industry and society, the concept of product/service-systems (PSS) is a promising approach to product development, which may yield product offers that benefit the company, customer and society alike. Only recently...... while maintaining a high level of need satisfaction [Mont 2004]. The enhancement of goods with the provision of services has been practised in some industrial sectors for decades, mainly based on maintenance deliveries to capital investments in B2B settings. Researchers working with these business....../service-oriented strategy we believe companies can deliver superior value solutions and ensure more optimal utilisation of resources by aligning operations with their customers compared to traditional product-oriented offers. The corresponding integration is not reflected in existing models and processes of product...

  3. Scientific Opportunities to Reduce Risk in Nuclear Process Science

    International Nuclear Information System (INIS)

    Bredt, Paul R.; Felmy, Andrew R.; Gauglitz, Phillip A.; Hobbs, David T.; Krahn, Steve; Machara, N.; Mcilwain, Michael; Moyer, Bruce A.; Poloski, Adam P.; Subramanian, K.; Vienna, John D.; Wilmarth, B.

    2008-01-01

    Cleaning up the nation's nuclear weapons complex remains as one of the most technologically challenging and financially costly problems facing the U.S. Department of Energy (DOE). Safety, cost, and technological challenges have often delayed progress in retrieval, processing, and final disposition of high-level waste, spent nuclear fuel, and challenging materials. Some of the issues result from the difficulty and complexity of the technological issues; others have programmatic bases, such as contracting strategies that may provide undue focus on near-term, specific clean-up goals or difficulty in developing and maintaining stakeholder confidence in the proposed solutions. We propose that independent basic fundamental science research focused on the full cleanup life-cycle offers an opportunity to help address these challenges by providing (1) scientific insight into the fundamental mechanisms involved in currently selected processing and disposal options, (2) a rational path to the development of alternative technologies should the primary options fail, (3) confidence that models that predict long-term performance of different disposal options are based upon the best available science, (4) fundamental science discovery that enables transformational solutions to revolutionize the current baseline processes.

  4. Child Development in a Changing World : Risks and Opportunities

    OpenAIRE

    Boyden, Jo; Dercon, Stefan; Singh, Abhijeet

    2015-01-01

    This review explores current understandings of child development and the consequences for children of risk exposure in low- and middle-income countries by integrating empirical evidence from development economics with insights from allied social science disciplines. It provides a holistic perspective that highlights the synergies between children's developmental domains, drawing particular attention to dimensions such as self-efficacy, self-esteem and aspirations, which have had only limited ...

  5. [Combine fats products: methodic opportunities of it identification].

    Science.gov (United States)

    Viktorova, E V; Kulakova, S N; Mikhaĭlov, N A

    2006-01-01

    At present time very topical problem is falsification of milk fat. The number of methods was considered to detection of milk fat authention and possibilities his difference from combined fat products. The analysis of modern approaches to valuation of milk fat authention has showed that the main method for detection of fat nature is gas chromatography analysis. The computer method of express identification of fat products is proposed for quick getting of information about accessory of examine fat to nature milk or combined fat product.

  6. Nano-enabled environmental products and technologies - opportunities and drawbacks

    DEFF Research Database (Denmark)

    Møller Christensen, Frans; Brinch, Anna; Kjølholt, Jesper

    The project aims to investigate the benefits for health and environment that the use of nanomaterials in products and technologies may have. More specifically, the project provides an overview of the most relevant nano-enabled environmental technologies, different types of products and technologies...... on the (Danish) market, as well as products and technologies, which are still in R&D and it will provide a qualitative overview of health and environmental pros and cons of these technologies. The project has focused on technologies applied in: 1) purification of water and wastewater, 2) remediation of soil...

  7. Students' Reactions to Climate Change Adaptation Risks and Opportunities

    Science.gov (United States)

    Thiel, M.; Grant, J. H.

    2015-12-01

    Objectives/Scope How undergraduate (UG) business students at a major public university in the Rocky Mountain region develop appreciation, and some understanding of physical and natural sciences causing climate change (CC) and their implications for society through examples drawn from the students' immediate and meaningful physical environments. Methods, Procedures, Process Three regional examples of ways in which CC impacts the lives of students on the local campus will provide practical approaches for students' environmentally responsible actions beyond the classroom. The cases from different industries will help UG students learn how they play critical roles in preventing and managing natural hazards, disaster management, ecology, development, famine, and secure livelihoods. Observations, Results, Conclusions Classroom discussions of "businesses' ecological responsibilities" in some remote location often fail to "connect" with students who have spent most of their lives within 300 miles of campus. However, when businesses in Asia are adding particulate to the atmosphere in the jet stream over the Pacific, and subsequently graying the local ski slopes, causing early melting and delaying the start of ski seasons, that is a different matter! However, more summer activities offer economic opportunities! A second example is found among the local entrepreneurial woodworkers who take "beetle kill" pine trees that are wildfire hazards and convert them into beautiful, creatively described "blue pine" furniture, interior beams, wall panels and table-top decorations. The "industrial scale" anaerobic digesters used in the "circular economy" of giant cheese factories, dairy farms and packing plants offer a third example for linking business to chemistry, engineering, and aesthetics (odor reduction).

  8. Scientific Opportunity to Reduce Risk in Groundwater and Soil Remediation

    Energy Technology Data Exchange (ETDEWEB)

    Pierce, Eric M.; Freshley, Mark D.; Hubbard, Susan S.; Looney, Brian B.; Zachara, John M.; Liang, Liyuan; Lesmes, D.; Chamberlain, G. M.; Skubal, Karen L.; Adams, V.; Denham, Miles E.; Wellman, Dawn M.

    2009-08-25

    In this report, we start by examining previous efforts at linking science and DOE EM research with cleanup activities. Many of these efforts were initiated by creating science and technology roadmaps. A recurring feature of successfully implementing these roadmaps into EM applied research efforts and successful cleanup is the focus on integration. Such integration takes many forms, ranging from combining information generated by various scientific disciplines, to providing technical expertise to facilitate successful application of novel technology, to bringing the resources and creativity of many to address the common goal of moving EM cleanup forward. Successful projects identify and focus research efforts on addressing the problems and challenges that are causing “failure” in actual cleanup activities. In this way, basic and applied science resources are used strategically to address the particular unknowns that are barriers to cleanup. The brief descriptions of the Office of Science basic (Environmental Remediation Science Program [ERSP]) and EM’s applied (Groundwater and Soil Remediation Program) research programs in subsurface science provide context to the five “crosscutting” themes that have been developed in this strategic planning effort. To address these challenges and opportunities, a tiered systematic approach is proposed that leverages basic science investments with new applied research investments from the DOE Office of Engineering and Technology within the framework of the identified basic science and applied research crosscutting themes. These themes are evident in the initial portfolio of initiatives in the EM groundwater and soil cleanup multi-year program plan. As stated in a companion document for tank waste processing (Bredt et al. 2008), in addition to achieving its mission, DOE EM is experiencing a fundamental shift in philosophy from driving to closure to enabling the long-term needs of DOE and the nation.

  9. Review of Residential Comfort Control Products and Opportunities

    Energy Technology Data Exchange (ETDEWEB)

    Metzger, Cheryn E. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Goyal, Siddharth [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Baechler, Michael C. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States)

    2017-12-15

    This paper begins by discussing the interaction of each major component in advanced sensor and control applications related to HVAC equipment. The paper also looks at the applications of these components to commissioning, maintenance and operations of the HVAC equipment in residential buildings. A summary of state-of-the-art product features is also provided. These products are categorized through their primary application type (commissioning/maintenance or operation) and the features are categorized by component type (sensors, data storage, human-in-the-loop, communication, and controls). A common theme that emerges from this study is the importance of the ability for various product categories to be connected to each other. There are many manufacturers of sensors and many manufacturers of controls, but the power to automate any commissioning, maintenance or operation application, requires connectivity.

  10. New paradigms in cervical cancer prevention: opportunities and risks

    Directory of Open Access Journals (Sweden)

    Giorgi Rossi Paolo

    2008-12-01

    Full Text Available Testing for the DNA of high-risk types of papilloma virus (HPV is more sensitive than cytology in detecting pre-cancerous lesions. One of the main advantages will be the possibility of applying prolonged screening intervals. However adequate screening protocols (age of start and stop, screening intervals, management of HPV positive women need to be applied in order to avoid over-referral to colposcopy and over-treatment and to maintain sustainable costs. Further follow-up of running trials and research on molecular markers will better define these parameters. The new situation will require organised screening programmes with rigorous protocols and monitoring. This will be even more needed when women vaccinated for HPV 16 and 18 will be screened. Research on how to best screen vaccinated women is a priority. This paper proposes an overview of the plausible impact of new technologies in cervical cancer screening in the near future and in the vaccinated cohorts.

  11. Power production at minimum risk

    International Nuclear Information System (INIS)

    Fremlin, J.H.

    1983-01-01

    A summary, including extensive quotations, is given of the main themes of a lecture by Prof. Fremlin in which he assessed the risks inherent in the use of various power systems. Considering only hazards which affect members of the public, the methods used to quantify such risks are examined. Both so-called inconspicuous hazards from radiation effects and conspicuous risks from accidents which could arise from nuclear power stations are compared to those from other types of power generation. The small risk arising from nuclear wastes is stressed. The lecturer concluded that he would not let 'tiny differences of risk' affect his decisions on energy planning. (U.K.)

  12. Nanotechnology development in Denmark - Environmental opportunities and risk

    DEFF Research Database (Denmark)

    Andersen, M.M.; Rasmussen, B.

    2006-01-01

    The present report represents the nanostudy part of a larger study entitled “Green Technology Foresight about Environmentally Friendly Products and Materials – Challenges from Nanotechnology, Biotechnology and ICT” (Jørgensen et al. 2006). The study wasmade for the Danish Environmental Protection...... (forthcoming in summer 2006). The analysis focuses not only on the environmental impact but even more on the dynamics involved in nanotechnology development ofwhich we currently know very little. Applying an innovation economic perspective focus is placed on analysing the direction of the nano search...... and technology development processes and how environmental issues enter into these. Hereby, the futuretrajectories of nanotechnology development is sought captured, indicating likely long-term perspectives of the Danish nanotechnology development. The content of the report is as follows: What is nanotechnology...

  13. Direct-to-consumer testing: more risks than opportunities.

    Science.gov (United States)

    Lippi, G; Favaloro, E J; Plebani, M

    2011-12-01

    As a result of incessant genetic discoveries and remarkable technological advancements, the availability and the consequent consumer's request for genetic testing are growing exponentially, leading to the development of a 'parallel' market, i.e. the direct-to-consumer (DTC) testing, also known as 'direct access testing' (DAT). Analogous to the traditional laboratory diagnostics, drawbacks of DTC testing might arise from any step characterising the total testing process, and include poor control of both appropriateness and preanalytical requirements, potential operation outside national or international regulation for in vitro diagnostic testing, little evidence of quality as well as the risk of transfer of genetic materials from the companies to other entities. Another important issue is the test panels offered to consumers, which are often based on preliminary, speculative or unsupported scientific information. Finally, the potential of this type of testing to generate anxiety or false reassurance should also be carefully considered. Although DTC testing carries some theoretical advantages (e.g. greater consumer autonomy and empowerment), solid clinical studies and costs vs. benefit analyses are needed to definitely establish whether DTC testing might be effective for decreasing the burden of diseases, delay their onset or modify their progression and therefore the clinical outcome. © 2011 Blackwell Publishing Ltd.

  14. Computer integration of engineering design and production: A national opportunity

    Science.gov (United States)

    1984-01-01

    The National Aeronautics and Space Administration (NASA), as a purchaser of a variety of manufactured products, including complex space vehicles and systems, clearly has a stake in the advantages of computer-integrated manufacturing (CIM). Two major NASA objectives are to launch a Manned Space Station by 1992 with a budget of $8 billion, and to be a leader in the development and application of productivity-enhancing technology. At the request of NASA, a National Research Council committee visited five companies that have been leaders in using CIM. Based on these case studies, technical, organizational, and financial issues that influence computer integration are described, guidelines for its implementation in industry are offered, and the use of CIM to manage the space station program is recommended.

  15. Opportunities to improve oil productivity in unstructured deltaic reservoirs

    Energy Technology Data Exchange (ETDEWEB)

    1991-01-01

    This report contains presentations presented at a technical symposium on oil production. Chapter 1 contains summaries of the presentations given at the Department of Energy (DOE)-sponsored symposium and key points of the discussions that followed. Chapter 2 characterizes the light oil resource from fluvial-dominated deltaic reservoirs in the Tertiary Oil Recovery Information System (TORIS). An analysis of enhanced oil recovery (EOR) and advanced secondary recovery (ASR) potential for fluvial-dominated deltaic reservoirs based on recovery performance and economic modeling as well as the potential resource loss due to well abandonments is presented. Chapter 3 provides a summary of the general reservoir characteristics and properties within deltaic deposits. It is not exhaustive treatise, rather it is intended to provide some basic information about geologic, reservoir, and production characteristics of deltaic reservoirs, and the resulting recovery problems.

  16. Opportunities and risks in Turkmenistan’s quest for diversification of its gas export routes

    International Nuclear Information System (INIS)

    Lee, Yusin

    2014-01-01

    This paper applies two hypotheses regarding weak state foreign policy to analyze the opportunities and risks in Turkmenistan’s quest to diversify its gas export routes, especially since 2006. The first hypothesis, related to opportunities, is that competition among major powers over the allegiance of weak states strengthens their bargaining power. The second hypothesis, related to risks, is that the diversification policies of weak states in times of decreasing competition among great powers incur the danger of simply replacing an old master with a new one. I argue that while the first hypothesis is useful in explaining the opportunities of Turkmenistan’s diversification policies, especially before early 2009, the second hypothesis is helpful in accounting for the risks of these policies after early 2009. In other words, competition among four major powers, Russia, China, the EU, and India, over Turkmenistan’s gas pipeline system before early 2009 strengthened the country’s bargaining power. In contrast, Turkmenistan’s diversification policies in times of fading competition after early 2009 have left it increasingly exposed to the potential risk of replacing its old master, Russia, with a new one, China. - Highlights: • This paper examines Turkmenistan’s policies of diversifying its gas export routes. • Turkmenistan’s diversification policies carry both opportunities and risks. • Turkmenistan has the opportunity to enhance its bargaining power. • Turkmenistan faces the risk of replacing an old master, Russia, with a new one, China. • This opportunity and risk have varying implications for Turkmenistan’s security of demand

  17. Russian food products marke: New CEFTA export opportunity

    Directory of Open Access Journals (Sweden)

    Stanojević Nataša

    2016-01-01

    Full Text Available This study aims to point out the unexploited export potential of CEFTA economies to the Russian market, using both quantitative and qualitative methods. More precisely, the Russian food market is examined, because of its size, the lack of domestic supply and actual changes of trading partners due to political and security antagonisms. The competitiveness of CEFTA food production on the Russian food market was analyzed by using two classical instruments of competitiveness - coefficient of conformity (CC and real effective exchange rate (RER.CC is applied first to the CEFTA export and Russian import of food in total, and then to the six main Russian import food products. The results indicate the highest degree of matching between Russian import and all CEFTA country export of fruits, vegetable and its processed commodities. RER is calculated to show competitiveness in terms of prices in bilateral trade, and result shows a very favorable ratio of currency, except in the case of Montenegro and Bosnia because their fixation to euro. Due to the small size of CEFTA production and non-proportional large Russian market, the interconnection, e.g. forming the value chain made of CEFTAs agriculture and food industry companies is suggested as the basis of new CEFTA export strategy.

  18. Navigating the new deregulated landscape: Opportunities and risks for wind energy

    Energy Technology Data Exchange (ETDEWEB)

    Fossum, D.J.; Hill, D.R. [Wiley, Rein & Fielding, Washington, DC (United States)

    1997-12-31

    Major changes in the law governing the electric industry are underway, fundamentally altering how the generation and sale of electric power is regulated and how electric power is marketed in the United States. Legislative and regulatory initiatives promoting competition will create a variety of opportunities, and commensurate risks, for power generators, marketers, brokers, sellers, and purchasers. To succeed in the new marketplace, suppliers of renewable energy must understand the changes occurring on the state and federal levels, and position themselves to take advantage of the opportunities available. In this environment, monitoring and participating in state and federal legislative and regulatory efforts will be crucial for maximizing opportunities for wind energy.

  19. Innovation in English Gothic Architecture: Risks, Impediments, and Opportunities

    Directory of Open Access Journals (Sweden)

    Paul Binski

    2017-06-01

    Full Text Available Medieval invention is considered first in relation to the powers of the rational and the irrational: the outcome of an artefact may have particular persuasive (more rarely supernatural force which casts light on the makers of the artefact themselves. Was especially remarkable art necessarily the product of virtue? The answer in Antiquity and the medieval world was clearly “no”. The rational and rhetorical idea of persuasion touched and blurred with the idea of seduction, and the agency in the making of an artefact might appear supernatural, free of human agency. But exceptional effects are not norms, and the concern of this paper is with the everyday, the social, rather than the exceptional and unique. This is explored in the second half by thinking about rules and conventions that are agreed socially, and in regard to which the aesthetic and the ethical once more touch and blur. Stress is laid on the medieval pleasures of taking conventions and playing with them in the process of art realization, a social process which could ultimately reaffirm the authority of traditional starting points.

  20. Telemedicine: opportunities and risks; Telemedizin: Chancen und Risiken

    Energy Technology Data Exchange (ETDEWEB)

    Vogl, R. [IT-Abteilung, Tiroler Landeskrankenanstalten GmbH, Innsbruck (Austria)

    2002-05-01

    Problem. Due to the rapid progress in the fields of information technology and data networks, telemedicine applications are growing in number. Besides curative telemedicine, the electronic exchange of medical data and the integration of health information systems between health care providers is gaining importance. Through the improved accessibility of electronic patient record information, considerable risks arise.Methods. A project for the interconnection of medical picture archiving and communication systems (PACS) between several hospitals is presented and the possibilities for further developing such networking systems utilizing new software technologies for transparent data access between different locations (GRID) and for decision support (software agents) are considered.Results. The availability of the electronic patient record via the data network and the perspective of semi intelligent software systems automatically preparing the data bears great potential for a boost in treatment quality and efficiency. Systems for unique electronic patient identification and for secure digital signature are a prerequisite, but per se not enough to ensure the protection of data against illegitimate access.Conclusion. Despite quality and efficiency benefits, challenges in the protection of sensible data and in the change of the physicians role result. (orig.) [German] Fragestellung. Durch die rasante Entwicklung der Informationstechnologie und der Datennetzwerke werden auch telemedizinische Applikationen immer zahlreicher eingesetzt. Neben der kurativen Telemedizin, die medienwirksame Erfolge verbuchen kann, gewinnen der elektronische Datenaustausch und die Gesundheitseinrichtungen uebergreifende Informationssystemintegration wachsende Bedeutung. Aus der besseren Zugaenglichkeit der elektronischen Krankengeschichtsinformation ergeben sich neben Chancen auch Risiken.Methodik. Ein Beispielprojekt fuer die Vernetzung von medizinischen Bildarchivierungssystemen (PACS

  1. Minimum Risk Pesticide: Definition and Product Confirmation

    Science.gov (United States)

    Minimum risk pesticides pose little to no risk to human health or the environment and therefore are not subject to regulation under FIFRA. EPA does not do any pre-market review for such products or labels, but violative products are subject to enforcement.

  2. Diagnosing risks in product-innovation projects

    NARCIS (Netherlands)

    Halman, Johannes I.M.; Keizer, J.A.

    A new method of diagnosing risks in product-innovation projects is introduced in the paper. The method is an improvement on existing risk methods used on product-innovation projects, such as potential problem analysis and failure mode and effects analysis. Technological, organizational and

  3. Diagnosing risks in product-innovation projects

    NARCIS (Netherlands)

    Halman, J.I.M.; Keizer, J.A.

    1994-01-01

    A new method of diagnosing risks in product-innovation projects is introduced in the paper. The method is an improvement on existing risk methods used on product-innovation projects, such as potential problem analysis and failure mode and effects analysis. Technological, organizational and

  4. ARIES Oxide Production Program Assessment of Risk to Long-term Sustainable Production Rate

    Energy Technology Data Exchange (ETDEWEB)

    Whitworth, Julia [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Lloyd, Jane Alexandria [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Majors, Harry W. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2017-05-04

    This report describes an assessment of risks and the development of a risk watch list for the ARIES Oxide Production Program conducted in the Plutonium Facility at LANL. The watch list is an active list of potential risks and opportunities that the management team periodically considers to maximize the likelihood of program success. The initial assessments were made in FY 16. The initial watch list was reviewed in September 2016. The initial report was not issued. Revision 1 has been developed based on management review of the original watch list and includes changes that occurred during FY-16.

  5. OPPORTUNITIES AND RISKS IN A CONTROL SYSTEM OF INNOVATIVE PROJECTS OF ORGANIZATIONAL DEVELOPMENT

    Directory of Open Access Journals (Sweden)

    A.V. Grebenkin

    2008-06-01

    Full Text Available The definition of the organizational development innovative project and the technique of its estimation is in this article offered. The distinctive special feature of this method is comparison of opportunities and risks by means of essentially new system of the parameters. These parameters allow to receive a complex estimation of a condition of organizational development innovative projects. Approbation of the offered estimated technique has been lead on set of organizational development innovative projects which were realized at the enterprises of a various branch accessory. The hypothesis about necessity of definition of a condition of the project by means of an estimation of opportunities and their comparisons to risks is confirmed.

  6. Bigger opportunities of oil investment in Colombia, exploration and production

    International Nuclear Information System (INIS)

    Arenas, Ismael Enrique

    1997-01-01

    In accordance with that philosophy are occurring new and important steps to reinforce the oil sector: the amplification of the exploratory frontier by means of the incorporation of a bigger number of sedimentary areas, and the adoption of novel recruiting instruments. It is aware of the competition that exists in the attainment of fresh capitals of risk for the developments of the sector, but, equally optimistic of Colombia offers; the author explains the reach of the change that is giving to the system of oil recruiting, with the purpose of to incentive the exploratory investment and to guarantee to the country the self-sufficiency and the generation of surpluses exportable, bigger economic incentives for exploration of new areas with the purpose of enlarging the exploratory frontier. Stimuli to the exploration with areas that have projection for small fields, and more favorable conditions for the search of natural gas projects in front of the established terms for the petroleum by the govern, among other topics treaties

  7. Arch Venture Partners' investment considerations for CBRNE products and opportunities

    Science.gov (United States)

    Crandell, K.; Lazarus, S.; Gardner, P. J.

    2008-04-01

    ARCH is interested in building leading, highly-valued companies from leading research. Toward that end we value innovations created by the leading researchers in the world, many of which are funded to solve critical scientific challenges including those in the instrumentation and CBRNE area. The most important CBRNE innovations we have seen at ARCH are breakthroughs involving significant unaddressed technology risk and have the potential for broad proprietary intellectual property as a result. The model ARCH has evolved in instrumentation is to look for a breakthrough innovation, with strong intellectual property and continue to strengthen the patent estate through the life of the company. ARCH looks to build companies around leading interdisciplinary scientific and engineering teams, and we favor platform technology that can be applied to multiple market applications both commercial and government. As part of a strategy to build a great company, addressing important CBRNE challenges can help a company strengthen its technical team and its IP estate. This supports a focus on early low volume markets on the way toward addressing a fuller portfolio of applications. Experienced Venture Capitalists can help this process by identifying important executive talent, partners and applications, offering financial syndication strength, and helping shape the company's strategy to maximize the ultimate value realized.

  8. Products of steel slags an opportunity to save natural resources.

    Science.gov (United States)

    Motz, H; Geiseler, J

    2001-01-01

    already accepted as a CEN standard and are used for a continuous quality control. Usually the suitability of steel slags is stated by fulfilling the requirements of national and/or international standards and regulations. Based on these standards and regulations in Germany in 1998 about 97% of the produced steel slags have been used as aggregates for road construction (e.g. as surface layer, road base and sub base for high trafficked roads), ways, earthworks, and armourstones for hydraulic structures. Consistent to the successful long-term experience not only products of steel slags but also products of blast furnace slags have been eliminated from the European Waste Catalogue and the European Shipment of Waste Regulation of the European Community, as well as from the lists of OECD for transfrontier movements by the decision of the OECD-Council from 21 September, 1995.

  9. Risk Of Loss Of Productivity In Workplaces

    Directory of Open Access Journals (Sweden)

    Wafi Assiri

    2015-08-01

    Full Text Available In every organization there exist some unavoidable cost when running any business. However these costs can be minimized by managing the factors that contribute to increased business cost and finding ways to prevent risks before they occur. This paper examines one of these factors which is loss of productivity in the workplace. The paper examines the risks of loss of productivity what causes these risks and in what ways will the business be affected by them. This paper also present the various ways a business can manage the risks by providing ways on how the business can prepare for any incidents with regards to the risks. And because its impossible to manage anything that you cant measure ways in which productivity can be measured have been addressed. Finally the paper addresses ways in which the business can improve its workplace productivity to achieve the business goals and ensure continuity of the business.

  10. PROVIDING AGRICULTURAL RISKS IN THE REPUBLIC OF MOLDOVA: TRENDS, PROBLEMS AND OPPORTUNITIES

    Directory of Open Access Journals (Sweden)

    Iulia CAPRIAN

    2015-01-01

    Full Text Available In this paper, the author presents results of scientific researches on the problems which farmers of the Republic of Moldova are facing in the field of risk management and insurance. In conclusion, the author formulates recommendations on farm managers’ opportunities to benefit from subsidized insurance, but also some recommendations resulting from the research of the experience of other countries from the European Union aimed to ensure the entrepreneurial risks in agricultural entities.

  11. Online communication among adolescents: An integrated model on its attraction, opportunities, and risks.

    NARCIS (Netherlands)

    Valkenburg, P.M.; Peter, J.

    2011-01-01

    Adolescents far outnumber adults in their use of e-communication technologies, such as instant messaging and social network sites. In this article, we present an integrative model that helps us to understand both the appeal of these technologies and their risks and opportunities for the psychosocial

  12. Studies of necessity and opportunity in the field of industrial risk

    International Nuclear Information System (INIS)

    Stefanescu, I.; Cristescu, I.

    1995-01-01

    This paper presents a study of necessity and opportunity of risk analyses in industrial installations with potential dangerous activity. The input data for this study were provided from a large number of industrial units all over the country. The obtained results point to the importance of such studies especially in case of nuclear facilities

  13. Proposal of a classification system for opportunities to innovate in skin care products.

    Science.gov (United States)

    Souza, I D da S; Almeida, T L; Takahashi, V P

    2015-10-01

    What are the opportunities to innovate in a skin care product? There are certainly many opportunities and many technologies involved. In this work, we assumed the role of identifying and categorizing these opportunities to develop a comprehensive and intelligible classification system, which could be used as a tool to support decision-making in different professional contexts. Initially, we employed the Delphi method to identify, discuss and standardize the opportunities to innovate in a skin care product. Finally, we used the classification system obtained in the previous phase to label patent applications, therefore, testing the suitability and utility of the system. At the end of the process, we achieved a 10-category classification system for opportunities to innovate in skin care products, and we also illustrated how this system could be used. The resultant classification system offers a normalized terminology for cosmetic scientists interested in dealing with the particularities of incremental and radical innovations in skin care products. © 2015 Society of Cosmetic Scientists and the Société Française de Cosmétologie.

  14. Risks and opportunities management on laser Megajoule project: the development of a new knowledge

    International Nuclear Information System (INIS)

    Delafosse-Le Ber, H.; Deysson, St.; Briault, S.

    2004-01-01

    The interest of these six years spent to build the management through the Risks and the Opportunities (R and O) approach on the project Megajoule Laser as well did not hold with the practical application of a method as to the installation of a formal culture and to its evolution in time. This culture, it had to be progressively founded within a mainly technical project team. More qualitative with most quantitative aspects, the putting into practice of the R and O approach on project LMJ knew all the degrees of evolution and precision. The starting of the project saw being born the first analysis of its 'Project Risk' with a series of interviews, carried out by the Quality Manager at the time. This analysis took the shape of a technical item lists, which are identified in an empirical way. Then, some brainstorming meeting were led under the responsibility of the Technical Coordinator (which is the Project Manager assistant) in order to identify and to evaluate the 'Project Risk' on a qualitative way, but always keeping a strong technical connotation. The methodological reference of the 'Project Risk' was outlined taking into account the DGA AQ 923 without directly interaction with the other project processes (for example, the cost, the deadlines and the performance management). Initially, the project developed an Access database, which allows the storing of the risk files. Unfortunately, this database is isolated from the other project management data processing tools. In the second time, the project decided to obtain a dedicated organisation, hierarchically independent from the technical managers but however integrated into the project and attached to the assistant of the Control Project Manager. This organisation being called 'Risks and Opportunities Team', when the management of the opportunities supplemented the R and O approach. This team combines today the individual interviews and the Working Groups in order to identify and to evaluate the effects of the R

  15. How to manage project opportunity and risk why uncertainty management can be a much better approach than risk management

    CERN Document Server

    Ward, Stephen

    2011-01-01

    Since I wrote the Foreword for the second edition of this book, risk management processes have become much more widely used, but controversy about what should be done and how best to do it has grown. Managing risk is a risky business. Chapman and Ward provide an in-depth explanation of why it is important to understand and manage underlying uncertainty in all its forms, in order to realise opportunities more fully and enhance corporate performance. They show what best practice should look like. The implications go well beyond the conventional wisdom of project risk management, providing an enl

  16. The Opportunities Map at Cornell University: finding direction in dairy production medicine.

    Science.gov (United States)

    Mitchell, Hilda M; Nydam, Daryl V; Reyher, Kristen; Gilbert, Robert O

    2004-01-01

    Discussion between faculty and interested students revealed the existence of a multitude of opportunities in dairy production medicine at the College of Veterinary Medicine at Cornell University. Many of these were not well known to students, or even to some of the faculty, and the means of accessing specific learning experiences were sometimes obscure. Together, an informal group of faculty, students, and alumni set about cataloging available educational opportunities, resulting in a 31-page publication referred to as the "Opportunities Map." Essentially a student handbook for production medicine students, the Opportunities Map at Cornell helps guide the travel of food animal-interested students through the curriculum without missing the important highlights along the way. The map was originally developed to chronicle the opportunities and resources available to students, but it has also been used to foster face-to-face communications between students and faculty, to welcome incoming students with production animal interests, and to provide a baseline description for further discussion about the curriculum.

  17. Risk management in facility transition and management decision making: Needs and opportunities

    International Nuclear Information System (INIS)

    Stillwell, W.; Seaver, D.; Keller, J.; Smith, D.; Weaver, D.; Sanders, T.; Thullen, P.

    1993-02-01

    An overall approach to risk management is described in this paper. Many of these concepts have been developed and applied as part of Hanford Mission Planning (HMP) (Hanford Mission Plan, 1992). At Hanford, HMP provides a mechanism for integrating planning across all the missions and programs of the site. This paper discusses the decision context within which EM must make and defend decisions, the types of decisions that are being and will need to be made in order to progress with the cleanup of the DOE complex, and the resulting need for risk management. Risk management, in turn, requires quality health and ecological risk information to make these decisions. Other types of information are also needed, but the risk information is typically the most important and the most difficult to obtain. The paper then describes a general technical approach to risk management, including particular methods for developing the high quality of human health and ecological risk information that will be needed to support risk management. We next turn to several special issues that make risk management more complex than many other decisions. We discuss these issues and offer some practical suggestions with respect to addressing them in the risk management framework. Finally, we conclude with some discussion of other opportunities for applying risk management

  18. Liberalising European electricity markets: opportunities and risks for a sustainable power sector

    International Nuclear Information System (INIS)

    Ringel, M.

    2003-01-01

    The process of liberalising European electricity markets, encompassing a wide range of restructuring activities, has mainly been spurred by the attempt to increase the economic efficiency of the whole sector. This process might be used to trigger a development towards a sustainable power sector by increasing the use of renewable energy sources and enhancing energy efficiency on the supply and demand side. However, by taking a closer look at the current trends of the European electricity markets, it becomes obvious that the liberalisation not only implies opportunities but also risks for the creation of a sustainable power sector. Many of these risks are due to market distortions and imperfections caused by the delay in creating a fully functional single European market. Thus, in the short-term, the market liberalisation tends to constitute more risks than opportunities without government actions to prevent these risks. In the long run, though, the efficiency gains of the sector and the appearance of new market factors are likely to bring forth the opportunities of liberalisation and actively foster a transformation towards a sustainable electricity sector. (author)

  19. The opportunity cost of family labor in the economy of the dairy production in Michoacan, Mexico

    Directory of Open Access Journals (Sweden)

    Randy Alexis Jiménez Jiménez

    2014-05-01

    Full Text Available The objective of this research is to analyze associated factors with the variation of the profit margin and the influence of the opportunity cost of family labor in the economic profit of the family dairy in the municipality of Maravatio, Michoacan. Productive economic information was obtained through the use of questionnaires, semi-structured interviews and direct observation, using the methodology of Participatory Action Research. The opportunity cost of workforce was established on the basis of the work options for the family members involved in the activity; the options were classified into three types: local, regional, and foreign, according to the location of the job opportunities. In order to determine the influence of family labor in earning, it was used a multiple regression model with inclusion of step-by-step variables. The livestock feed represented the highest index of determination of the profit margin variation with the 68 %. Family labor is one of the variables that have an adverse impact on the profitability of the production units, it represented 26% of the variation of economic gain, with a negative linear relation of -1.05 (P ≤0.001. The best labor alternatives for producers, when emigrating, show that family labor is not the productive factor allowing them to have earnings; however, the dairy activity provides productive and economic sustenance for people with a local and regional opportunity cost.

  20. Engaged scholarship for designing product service system innovation opportunities in an industrial design course

    NARCIS (Netherlands)

    Lu, Y.; Baha, S.E.; Hsieh, P.H.

    2013-01-01

    This paper explores a design case study in an industrial design classroom in which actors with diverse expertise were involved for the creation of Product Service System (PSS) innovation opportunities in societal contexts. By engaging diverse experts from different fields, the classroom was turned

  1. 76 FR 41178 - Pesticides; Policies Concerning Products Containing Nanoscale Materials; Opportunity for Public...

    Science.gov (United States)

    2011-07-13

    ... Pesticides; Policies Concerning Products Containing Nanoscale Materials; Opportunity for Public Comment; Extension of Comment Period AGENCY: Environmental Protection Agency (EPA). ACTION: Proposed policy statement; extension of comment period. SUMMARY: EPA issued a proposed policy statement in the Federal Register of June...

  2. Exploring opportunities for enhancing innovation in agriculture: The case of oil palm production in Ghana

    NARCIS (Netherlands)

    Adjei-Nsiah, S.; Sakyi-Dawson, O.; Kuyper, T.W.

    2012-01-01

    We carried out a study using key informant interviews, focus group discussions and individual interviews to explore opportunities to enhance innovation in the oil palm sector in Ghana. Current technical innovations at the farm level are insufficient to promote sustainable oil palm production and to

  3. Guide to resource conservation and cost savings opportunities in the soap, detergents and related products sector

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-03-01

    The soaps, detergents and related products sector is an important component of the chemical industry within Ontario, as these products are used for cleaning purposes in industrial, institutional and domestic consumer applications. This guide was prepared to assist the sector with cost savings and resource conservation. The guide highlights opportunities for resource conservation through energy and water efficiency improvements, more efficient utilisation of raw materials, and reduction of environmental releases at source. 54 figs.

  4. [Health risks from pest control products].

    Science.gov (United States)

    Pieper, C; Holthenrich, D; Schneider, H

    2014-05-01

    According to European biocide legislation, pest control products require assessment and authorization by the responsible national or European authorities. Biocidal products can only be authorized if they have no unacceptable effects on human health. The health risk assessment performed for authorization comprises (a) the derivation of reference values for the active substances and substances of concern contained in the biocidal product and (b) an exposure assessment. These parameters are required for risk characterization. No unacceptable health risks are expected if the determined exposure is less than the relevant reference value. In addition, the toxicological information is used for classification of the biocidal product. The assessment may, where necessary, result in specific conditions for use or other restrictions aimed at minimizing risk. The risk to human health from pest control products is mainly based on the toxicological properties of their active substances. Commonly, the coformulants used in pest control products are of less concern than the active substances (e.g., food ingredients and animal feed products). For example, most rodenticides belong to the group of anticoagulants, which are also effective in humans. Regarding intoxications through insecticides, the group of pyrethroids is of particular importance. Fumigants containing metal phosphides, hydrogen cyanide, or sulfuryl difluoride are particularly toxic. This toxicity is linked to the high acute inhalation toxicity of the gaseous active substances themselves or, in the case of phosphides, of the released gas phosphane. The aim of health risk assessment for the authorization of biocidal products is to ensure their safe application for users and all other persons involved, assuming an adequate and label-compliant use.

  5. 'Happy Onlife' - A video game to support mediation on internet risks and opportunities

    OpenAIRE

    CHAUDRON STEPHANE; DI GIOIA Rosanna; GEMO Monica; LAGAE KAAT

    2015-01-01

    Children and young people are very active users of digital technology from an early age. Recent research shows that children learn quickly from mirroring the behaviour of parents, of older siblings and peers. On one hand, children have acquired independency and skills within the digital world; on the other, they lack reflective and critical thinking as well as awareness about opportunities and risks such as cyber-bullying or digital identity theft. Active adult’s mediation would allow for the...

  6. Organic livestock production: an emerging opportunity with new challenges for producers in tropical countries.

    Science.gov (United States)

    Chander, M; Subrahmanyeswari, B; Mukherjee, R; Kumar, S

    2011-12-01

    Agrochemicals, veterinary drugs, antibiotics and improved feeds can increase the food supply while minimising production costs in various livestock production systems around the world. However, these days, quality-conscious consumers are increasingly seeking environmentally safe, chemical-residue-free healthy foods, along with product traceability and a high standard of animal welfare, which organic production methods are said to ensure. Organic production is not only a challenge for producers in developing countries, it offers new export opportunities as well. Organic agriculture is practised by 1.8 million producers in 160 countries, and production of organically grown food continues to increase steadily by 15% per year. Most tropical countries are now exporting organic agricultural products but, apart from organic beef from Brazil and Argentina, organic livestock products are yetto take off. Most trade in organic livestock products is restricted to the European Union and other developed nations. Nevertheless, tropical countries cannot afford to neglect this emerging system of animal production. Organic production is knowledge- and management-intensive. Producers must be well versed in organic production standards, principles and practices, which require a high degree of knowledge and skill. In organic production, it is not simply the final product but the whole production process that must be inspected and approved by the accredited certification bodies. Organic livestock farming is still evolving, and further research is needed to make it sustainable. In this paper, the authors review the prospects of organic animal husbandry and its possible constraints in developing and tropical countries.

  7. Peri-urban dairy production systems in developing countries: Characteristics, potential and opportunities for improvement

    International Nuclear Information System (INIS)

    Devendra, C.

    2002-01-01

    Full text: Peri-urban dairy production systems in developing countries are discussed with reference to type of systems, their characteristics, potential, and opportunities for improvement. Three types of dairy systems are identified and described: smallholder systems, smallholder co-perative dairy production systems, and intensive dairy production systems. The first two systems are by far the most important, and are associated with increasing intensification. Buffaloes are especially important in South Asia, but elsewhere dairy production mainly involves Holstein-Friesian cross-bred cattle. Dairy goats are important in some countries, but are generally neglected in development programmes. The expansion and intensification of peri-urban dairy production is fuelled by increased demand for milk with associated problems of milk handling and distribution, hygiene and environmental pollution. The major constraints to production are inter alia, choice of species, breeds and availability of animals; feed resources and improved feeding systems; improved breeding, reproduction, and animal health care; management of animal manure, and organised marketing, and market outlets. These constraints provide major opportunities and challenges for research and development to increase dairy production, efficient management of natural resources, and improved livelihoods of poor farmers. Specific areas for research are identified, as also the need of a holistic focus involving interdisciplinary research and integrated natural resource management, in a shared partnership between farmers and scientists that can demonstrate increased productivity and sustainable production systems. Suggestions for performance indicators for such systems are indicated. (author)

  8. Use of new scientific developments in regulatory risk assessments: challenges and opportunities.

    Science.gov (United States)

    Tarazona, Jose V

    2013-07-01

    Since the 1990s, science based ecological risk assessments constitute an essential tool for supporting decision making in the regulatory context. Using the European REACH Regulation as example, this article presents the challenges and opportunities for new scientific developments within the area of chemical control and environmental protection. These challenges can be sorted out in 3 main related topics (sets). In the short term, the challenges are directly associated with the regulatory requirements, required for facilitating a scientifically sound implementation of the different obligations for industry and authorities. It is important to mention that although the actual tools are different due to the regulatory requirements, the basic needs are still the same as those addressed in the early 1990s: understanding the ecological relevance of the predicted effects, including the uncertainty, and facilitating the link with the socio-economic assessment. The second set of challenges covers the opportunities for getting an added value from the regulatory efforts. The information compiled through REACH registration and notification processes is analyzed as source for new integrative developments for assessing the combined chemical risk at the regional level. Finally, the article discusses the challenge of inverting the process and developing risk assessment methods focusing on the receptor, the individual or ecosystem, instead of on the stressor or source. These approaches were limited in the past due to the lack of information, but the identification and dissemination of standard information, including uses, manufacturing sites, physical-chemical, environmental, ecotoxicological, and toxicological properties as well as operational conditions and risk management measures for thousands of chemicals, combined by the knowledge gathered through large scale monitoring programs and spatial information systems is generating new opportunities. The challenge is liking

  9. Failures of knowledge production in nuclear power risk management

    International Nuclear Information System (INIS)

    Sanne, Johan M.

    2008-09-01

    Risks are ascribed in processes of knowledge production, where risk objects are defined and measures taken. This knowledge is also the basis for regulatory action. Thus, uncertainties in knowledge production, based upon choices of assumptions, methods, calculations and evidence criteria for reliable data create vulnerabilities for risk management and risk regulation. A recent incident in Swedish nuclear power plant provides an opportunity to develop theories of knowledge production in complex organizations. Knowledge modes within nuclear power can be characterized as either calculated logics where evidence claims need numbers, real time logics based upon subtle signals and tacit knowledge or as policy logics, navigating between internal and external demands for safety, trustworthiness and profit. The plant had neither foreseen the triggering event nor designed the plant to withstand it. I analyze how the plant and the regulator have interpreted the event, its significance and the measures taken to prevent similar events. I also discuss alternative interpretations, lack of knowledge and the generic deficiencies in knowledge production that the event indicates. First, the plant was not as robustly designed as expected. Deficiencies in diversification may have been caused by overconfidence in the reliability of its design. Second, inadequate design was ascribed to various deficient knowledge production processes: original design of the plant, reconstruction or caused by inadequate learning from previous events. The failures in knowledge production were probably caused by insufficient integration of different knowledge processes and limitations in engineering analysis. Knowledge about risks from nuclear power operations is mainly based upon calculations and simulations, not upon real events. But knowledge and design could be improved also without accidents. Control room operators and maintenance staff can provide invaluable knowledge and methods; to improve causal

  10. Failures of knowledge production in nuclear power risk management

    Energy Technology Data Exchange (ETDEWEB)

    Sanne, Johan M.

    2008-09-15

    Risks are ascribed in processes of knowledge production, where risk objects are defined and measures taken. This knowledge is also the basis for regulatory action. Thus, uncertainties in knowledge production, based upon choices of assumptions, methods, calculations and evidence criteria for reliable data create vulnerabilities for risk management and risk regulation. A recent incident in Swedish nuclear power plant provides an opportunity to develop theories of knowledge production in complex organizations. Knowledge modes within nuclear power can be characterized as either calculated logics where evidence claims need numbers, real time logics based upon subtle signals and tacit knowledge or as policy logics, navigating between internal and external demands for safety, trustworthiness and profit. The plant had neither foreseen the triggering event nor designed the plant to withstand it. I analyze how the plant and the regulator have interpreted the event, its significance and the measures taken to prevent similar events. I also discuss alternative interpretations, lack of knowledge and the generic deficiencies in knowledge production that the event indicates. First, the plant was not as robustly designed as expected. Deficiencies in diversification may have been caused by overconfidence in the reliability of its design. Second, inadequate design was ascribed to various deficient knowledge production processes: original design of the plant, reconstruction or caused by inadequate learning from previous events. The failures in knowledge production were probably caused by insufficient integration of different knowledge processes and limitations in engineering analysis. Knowledge about risks from nuclear power operations is mainly based upon calculations and simulations, not upon real events. But knowledge and design could be improved also without accidents. Control room operators and maintenance staff can provide invaluable knowledge and methods; to improve causal

  11. Online communication among adolescents: an integrated model of its attraction, opportunities, and risks.

    Science.gov (United States)

    Valkenburg, Patti M; Peter, Jochen

    2011-02-01

    Adolescents far outnumber adults in their use of e-communication technologies, such as instant messaging and social network sites. In this article, we present an integrative model that helps us to understand both the appeal of these technologies and their risks and opportunities for the psychosocial development of adolescents. We first outline how the three features (anonymity, asynchronicity, and accessibility) of online communication stimulate controllability of online self-presentation and self-disclosure among adolescents. We then review research on the risks and opportunities of online self-presentation and self-disclosure for the three components of adolescents' psychosocial development, including identity (self-unity, self-esteem), intimacy (relationship formation, friendship quality, cyberbullying), and sexuality (sexual self-exploration, unwanted sexual solicitation). Existing research suggests several opportunities of online communication, such as enhanced self-esteem, relationship formation, friendship quality, and sexual self-exploration. It also yields evidence of several risks, including cyberbullying and unwanted sexual solicitation. We discuss the shortcomings of existing research, the possibilities for future research, and the implications for educators and health care professionals. Copyright © 2011 Society for Adolescent Health and Medicine. Published by Elsevier Inc. All rights reserved.

  12. RISK ANALYSIS APPLIED IN OIL EXPLORATION AND PRODUCTION

    African Journals Online (AJOL)

    ES Obe

    aDepartment of Civil Engineering, University of Nigeria, Nsukka, Enugu State, Nigeria. ... The analysis in this work is ... risk analysis, oil field, risk management, projects, investment opportunity. 1. .... own merit but since the company has limited.

  13. Sustainable Product Service Systems in Small and Medium Enterprises (SMEs: Opportunities in the Leather Manufacturing Industry

    Directory of Open Access Journals (Sweden)

    Ricardo J. Hernández Pardo

    2012-01-01

    Full Text Available This paper presents an approach to identify opportunities to develop sustainable Product Service Systems (PSS involving Small and Medium Enterprises (SMEs. The purpose of the research is to build understanding of how the integration of product and service design and the use of Information and Communication Technologies (ICT can contribute to identify opportunities to develop sustainable PSS involving SMEs. In order to develop the approach, research with 16 Colombian Manufacturing SMEs was carried out. A reference model and four generic types of PSS according to the relationships between product and service design and ICT are used to analyse the data. Finally, the possibility of extending the approach into a general framework to work with other industries is discussed.

  14. Exploring barriers and opportunities in adopting crowdsourcing based new product development in manufacturing SMEs

    Science.gov (United States)

    Qin, Shengfeng; Van der Velde, David; Chatzakis, Emmanouil; McStea, Terry; Smith, Neil

    2016-10-01

    Crowdsourcing is an innovative business practice of obtaining needed services, ideas, or content or even funds by soliciting contributions from a large group of people (the `Crowd'). The potential benefits of utilizing crowdsourcing in product design are well-documented, but little research exists on what are the barriers and opportunities in adopting crowdsourcing in new product development (NPD) of manufacturing SMEs. In order to answer the above questions, a Proof of Market study is carried out on crowdsourcing-based product design under an Innovate UK funded Smart project, which aims at identifying the needs, challenges and future development opportunities associated with adopting crowdsourcing strategies for NPD. The research findings from this study are reported here and can be used to guide future development of crowdsourcing-based collaborative design methods and tools and provide some practical references for industry to adopt this new and emerging collaborative design method in their business.

  15. Prepayment risk, impact on credit products

    Directory of Open Access Journals (Sweden)

    Dan Costin NIŢESCU

    2012-08-01

    Full Text Available Credit pricing is always an important aspect of operations of banks, as loans are generally two thirds of bank assets. Therefore, the study of factors influencing a bank customer behavior and their impact on early repayment of loans may have a significant influence in reducing the risk assumed by such unexpected operations.Objective analysis of prepayment risk is to estimate the probability of repayment to better manage its manifestation. The existence of potential customers that use this option exposes the bank to a number of risks, such as interest rate risk, the maturity mismatch risk and liquidity risk.Proper evaluation and forecasting the evolution of this risk can bring great benefits for a credit institution in the management of loan products and customer relationship: lower risk of over-ensure against fixed rate mortgage, a better management of short-term and long term liquidity needs (thus reducing the risk of over-financing can offer customers more competitive pricing (achieved by reducing funding costs due to better assessment and management of risks involved early repayment.

  16. Microbiological risk assessment for personal care products.

    Science.gov (United States)

    Stewart, S E; Parker, M D; Amézquita, A; Pitt, T L

    2016-12-01

    Regulatory decisions regarding microbiological safety of cosmetics and personal care products are primarily hazard-based, where the presence of a potential pathogen determines decision-making. This contrasts with the Food industry where it is a commonplace to use a risk-based approach for ensuring microbiological safety. A risk-based approach allows consideration of the degree of exposure to assess unacceptable health risks. As there can be a number of advantages in using a risk-based approach to safety, this study explores the Codex Alimentarius (Codex) four-step Microbiological Risk Assessment (MRA) framework frequently used in the Food industry and examines how it can be applied to the safety assessment of personal care products. The hazard identification and hazard characterization steps (one and two) of the Codex MRA framework consider the main microorganisms of concern. These are addressed by reviewing the current industry guidelines for objectionable organisms and analysing reports of contaminated products notified by government agencies over a recent 5-year period, together with examples of reported outbreaks. Data related to estimation of exposure (step three) are discussed, and examples of possible calculations and references are included. The fourth step, performed by the risk assessor (risk characterization), is specific to each assessment and brings together the information from the first three steps to assess the risk. Although there are very few documented uses of the MRA approach for personal care products, this study illustrates that it is a practicable and sound approach for producing products that are safe by design. It can be helpful in the context of designing products and processes going to market and with setting of microbiological specifications. Additionally, it can be applied reactively to facilitate decision-making when contaminated products are released on to the marketplace. Currently, the knowledge available may only allow a

  17. Provider-based Medicare risk contracting and subcontracting: opportunities and risks for provider sponsored organizations.

    Science.gov (United States)

    Levin, H A; Zenner, P A; Kipp, R A; Whitney, E L

    1997-01-01

    Provider sponsored organizations (PSOs) are increasingly acquiring the risk for the management of Medicare Risk patients by accepting capitation directly from the Health Care Financing Administration (HCFA) or through contracts with HMOs or other organizations contracting with HCFA. The Medicare population and the requirements that the federal administration has put into place with respect to risk contracting are unique and demand specific responses on the part of the PSO for a contract to be successful. The PSO is cautioned to understand the actuarial risk, the clinical uniqueness of the Medicare beneficiary, Medicare reimbursement regulatory requirements, utilization management needs, and necessary reporting before entering into a contractual arrangement. This article attempts to describe some of the more common issues a provider organization must consider.

  18. Managing Risk, Reducing Vulnerability and Enhancing Productivity ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Managing Risk, Reducing Vulnerability and Enhancing Productivity under a Changing Climate. The countries of the Greater Horn of Africa are particularly vulnerable to drought, exacerbated by widespread poverty and dependence on rainfed agriculture. Even with normal rainfall, the region does not produce enough food to ...

  19. On risk assessment of energy production

    International Nuclear Information System (INIS)

    Kunii, Katsuhiko

    2005-07-01

    Today we cannot ignore the risk of health and/or environment by energy production such as power generation since the risk has been made large enough. In this report an information survey has been done in order to know the outline and points of risk assessment. Based on the information of reports and literature about risk assessment, have been surveyed mainly the external cost assessment of power generation (in which quantification of health and/or environment risk has been done), in addition, risks of disasters, accidents, investments, finance etc. and impacts of those risks on social activities. The remarks obtained by the survey are as follows: 1) Some of external cost assessment of power generation show different results even if the assessment conditions of technology, site, etc. are mostly the same. It is necessary to remark on the information such as basic data, model, background, application limit of assessment considering the reliability. 2) Especially it is considered that the reliability of risk assessment is not enough at present because of the lack of basic data. (author)

  20. BARRIERS AND OPPORTUNITIES IN DEVELOPING 'DO-IT-YOURSELF' (DIY PRODUCTS FOR LOW-INCOME HOUSING

    Directory of Open Access Journals (Sweden)

    Priscilla Lepre

    2010-06-01

    Full Text Available Direct involvement of the user in the assembling process of his/her own products or even entire house is a reality among low-income populations in developing countries. Nevertheless, there are a limited number of products that have actually been designed from a do-it-yourself (DIY perspective, which results in several problems, such as poor user safety while the product is being assembled or inadequate results from an improvised assembling. Hence, the main goal of this paper is to analyse barriers to and opportunities for developing DIY products for low-income housing in developing countries. The research method utilises a case study of a DIY product consisting of a hybrid solution that acted as both a partition wall and a wardrobe. The identified opportunities included more systematic use of existing craft competencies among low-income families and the possibility of cost reduction through DIY concepts. Major barriers included the perception of the DIY product as inferior and the difficulty of communicating the DIY assembly process to users who quite often are illiterate.

  1. How to succeed in the digital age? Monitor the organizational context, identify risks and opportunities, and manage change effectively

    Directory of Open Access Journals (Sweden)

    Fonseca Luis Miguel

    2017-09-01

    Full Text Available Due to the dynamic and inter-connected internal and external environments of the present digital age, organizations are faced with increased challenges to achieve enduring success. After reviewing the major management theories with an organizational focus, and the changes brought with the new ISO 9001:2015 Quality Management Systems International Standard Edition, the hypotheses that to succeed in the digital age organizations must monitor the organizational context, identify risks and opportunities, and manage change effectively, are presented. A worldwide survey was carried out among IRCA registered auditors concerning ISO 9001:2015 certified organizations, and by using a quantitative methodology (sample normality was confirmed through Kolmogorov-Smirnov test and the hypothesis were tested by using Pearson correlation coefficient. The results of this research highlight the need to properly monitor the organizational (internal and external context and identify the key issues that affect the organizations ability to deliver quality products and satisfy their customers and key stakeholders, and to plan, design, implement and control change in an effective and timely manner. These results support the notion that organizations should adopt appropriate organizational models for the present digital age, with emphasis on knowledge management and horizontal customer perspectives, willing to scan the environment, identify risk and opportunities and take timely and suitable actions.

  2. Marine Sponge Derived Natural Products between 2001 and 2010: Trends and Opportunities for Discovery of Bioactives

    Science.gov (United States)

    Mehbub, Mohammad Ferdous; Lei, Jie; Franco, Christopher; Zhang, Wei

    2014-01-01

    Marine sponges belonging to the phylum Porifera (Metazoa), evolutionarily the oldest animals are the single best source of marine natural products. The present review presents a comprehensive overview of the source, taxonomy, country of origin or geographical position, chemical class, and biological activity of sponge-derived new natural products discovered between 2001 and 2010. The data has been analyzed with a view to gaining an outlook on the future trends and opportunities in the search for new compounds and their sources from marine sponges. PMID:25196730

  3. Evaluation of pig production practices, constraints and opportunities for improvement in smallholder production systems in Kenya.

    Science.gov (United States)

    Mbuthia, Jackson Mwenda; Rewe, Thomas Odiwuor; Kahi, Alexander Kigunzu

    2015-02-01

    This study evaluated pig production practices by smallholder farmers in two distinct production systems geared towards addressing their constraints and prospects for improvement. The production systems evaluated were semi-intensive and extensive and differed in remoteness, market access, resource availability and pig production intensity. Data were collected using structured questionnaires where a total of 102 pig farmers were interviewed. Qualitative and quantitative research methods were employed to define the socioeconomic characteristics of the production systems, understanding the different roles that pigs play, marketing systems and constraints to production. In both systems, regular cash income and insurance against emergencies were ranked as the main reasons for rearing pigs. Marketing of pigs was mainly driven by the type of production operation. Finances, feeds and housing were identified as the major constraints to production. The study provides important parameters and identifies constraints important for consideration in design of sustainable production improvement strategies. Feeding challenges can be improved through understanding the composition and proper utilization of local feed resources. Provision of adequate housing would improve the stocking rates and control mating.

  4. Stakeholder dialogues. Opportunities and risks of climate change; Stakeholder-Dialoge. Chancen und Risiken des Klimawandels

    Energy Technology Data Exchange (ETDEWEB)

    Hoffman, Esther; Gebauer, Jana; Dunkelberg, Elisa; Hirschfeld, Jesko; Hirschl, Bernd; Rotter, Maja; Stegnitz, Antje; Wurbs, Sven [Institut fuer oekologische Wirtschaftsforschung (IOeW), Berlin (Germany); Lotz, Wiebke; Welp, Martin [Hochschule fuer nachhaltige Entwicklung Eberswalde (F.H.) (Germany)

    2011-02-15

    Climate change as a global problem has specific local effects, which in addition to natural areas also affect social and technical systems. The consequences of climate change will differ concerning the different sectors and regions and can be associated with both risks and opportunities to be. To effectively protect against risks, but to also use opportunities, appropriate adaptation measures are needed. In this context, the Competence Centre on Climate Impacts and Adaptation in the Federal Environmental Agency (KomPass) introduced in 2009 and 2010 a series of stakeholder dialogues that culminated in a cross-thematic and cross-sectoral national conference ''Already adapted?''. The events were part of the research project ''Stakeholder Dialogues: Opportunities and Risks of Climate Change'', conducted by the Institute for Ecological Economy Research (IOeW) in cooperation with the University of Applied Sciences Eberswalde. Some dialogues were held in cooperation with partners from respective associations or authorities. The National Dialogue took place in cooperation with the agency compass orange. The aim of the dialogues was one hand to capture the need for action resulting from climate change, and analyze and develop approaches to adaptation strategies.The different sectors and industries were represented by associations and companies, ministries and authorities and by civil society and academia. On the other hand adaptation needs, demands on the political framework, and research and cooperation needs should be be assessed and analyzed in an interdisciplinary process. From this, KomPass will derive recommendations for the design of the national Action Plan Adaptation and feed into the ongoing process. (orig.)

  5. Stakeholder dialogues. Opportunities and risks of climate change; Stakeholder-Dialoge. Chancen und Risiken des Klimawandels

    Energy Technology Data Exchange (ETDEWEB)

    Hoffman, Esther; Gebauer, Jana; Dunkelberg, Elisa; Hirschfeld, Jesko; Hirschl, Bernd; Rotter, Maja; Stegnitz, Antje; Wurbs, Sven [Institut fuer oekologische Wirtschaftsforschung (IOeW), Berlin (Germany); Lotz, Wiebke; Welp, Martin [Hochschule fuer nachhaltige Entwicklung Eberswalde (F.H.) (Germany)

    2011-02-15

    Climate change as a global problem has specific local effects, which in addition to natural areas also affect social and technical systems. The consequences of climate change will differ concerning the different sectors and regions and can be associated with both risks and opportunities to be. To effectively protect against risks, but to also use opportunities, appropriate adaptation measures are needed. In this context, the Competence Centre on Climate Impacts and Adaptation in the Federal Environmental Agency (KomPass) introduced in 2009 and 2010 a series of stakeholder dialogues that culminated in a cross-thematic and cross-sectoral national conference ''Already adapted?''. The events were part of the research project ''Stakeholder Dialogues: Opportunities and Risks of Climate Change'', conducted by the Institute for Ecological Economy Research (IOeW) in cooperation with the University of Applied Sciences Eberswalde. Some dialogues were held in cooperation with partners from respective associations or authorities. The National Dialogue took place in cooperation with the agency compass orange. The aim of the dialogues was one hand to capture the need for action resulting from climate change, and analyze and develop approaches to adaptation strategies.The different sectors and industries were represented by associations and companies, ministries and authorities and by civil society and academia. On the other hand adaptation needs, demands on the political framework, and research and cooperation needs should be be assessed and analyzed in an interdisciplinary process. From this, KomPass will derive recommendations for the design of the national Action Plan Adaptation and feed into the ongoing process. (orig.)

  6. Respiratory risks in broiler production workers

    Directory of Open Access Journals (Sweden)

    M do CB de Alencar

    2004-03-01

    Full Text Available There are many situations that involve health risks to the Brazilian rural worker, and animal production is just one of them. Inhalation of organic dust, which has many microorganisms, leads in general to respiratory allergic reactions in some individuals, "asthma-like syndrome", and mucous membrane inflammation syndrome, that is a complex of nasal, eye, and throat complaints. Furthermore, workers might have farmer's hypersensitivity pneumonia, that is a respiratory health risk along the years. The objective of this study was to evaluate the potential pulmonary health risks in poultry production workers in the region of Curitiba, PR, Brazil. Interviews using a pre-elaborated questionnaire with 40 questions were made with 37 broiler production workers, which were submitted to a pulmonary function test. Results of restrictive function with lower FEV1 (the maximum respiratory potential, the forced expiratory volume in the first second of exhalation and FVC (forced vital capacity represented 24.32% of the total of workers, and severe obstruction represented 2.70%. Other symptoms were found in 67.57% of the workers as well. The results showed that those who work more than 4 years and within more than one poultry house, exceeding 5 hours per day of work, presented higher pulmonary health risks. It is concluded that the activities within broiler houses may induce allergic respiratory reaction in workers. The use of IPE (individual protection equipment besides special attention to the air quality inside the housing may be advised in a preventive way.

  7. OPPORTUNITIES AND RISKS OF GLOBALIZATION IN RURAL AREAS. CASE STUDY: BOTOSANI COUNTY

    Directory of Open Access Journals (Sweden)

    Maria-Simona Cuciureanu

    2014-04-01

    Full Text Available The global economy plays an important role in the development of a region or a county/district as it promotes the exploitation of resources and space in a logical and rational manner. The trend of global economic uniformity allows opportunities and risks to Botoșani County since globalization involves economic development and rising living standards, but loss of cultural values, traditions and customs. The area of study currently confronts with socio-economic and demographic changes that may be addressed by globalization, but at the same time spatial development according to global standards will cause the loss of Botoșani County’s authenticity.

  8. Strategic Management Accounting and Feed-forward Management: with Reference to the Unified Management of Profit Opportunity and Risk

    OpenAIRE

    西村, 明

    2015-01-01

    This paper aims toreexamine strategic management accouning in relation to profit opportunity and risk from the viewpoint of feed-forward management , as few studies to date have discuued the relations between management accounting and the unified management of profit opportunity and risk.Many studies have been conducted that emphasize non-fine information and feedback organizational management in an attept to make traditional management accounting relevant to practical strategic needs. As lon...

  9. Intent, Capability and Opportunity: A Holistic Approach to Addressing Proliferation as a Risk Management Issue

    Energy Technology Data Exchange (ETDEWEB)

    Amanda Rynes; Trond Bjornard

    2011-07-01

    Currently, proliferation risk assessment models are designed to evaluate only a portion of the overall risk, focusing exclusively on either technological or social factors to determine the extent of a threat. Many of these models are intended to act as a means of predicting proliferation potential rather than assessing the system as a whole, ignoring the ability to enhance mitigating factors and manage, rather just establish the presence of, the threat. While the information garnered through these forms of analysis is necessary, it remains incomplete. By incorporating political, social, economic and technical capabilities as well as human factors such as intent into a single, multi-faceted risk management model, proliferation risk can be evaluated more effectively. Framing this information around how to improve and expand the Regime already in place and establishing where there are gaps in the system allows for a more complete approach to risk management, mitigation and resource allocation. The research conducted here seeks to combine all three elements (intent, capability and opportunity) in a comprehensive evaluation which incorporates an assessment of state-level variables, possible proliferation pathways and technical capability. Each portion of the analysis is carried out independently then combined to illustrate the full scope of a State's nuclear infrastructure while showing areas of weakness in the institutional framework.

  10. Intent, Capability and Opportunity: A Holistic Approach to Addressing Proliferation as a Risk Management Issue

    International Nuclear Information System (INIS)

    Rynes, Amanda; Bjornard, Trond

    2011-01-01

    Currently, proliferation risk assessment models are designed to evaluate only a portion of the overall risk, focusing exclusively on either technological or social factors to determine the extent of a threat. Many of these models are intended to act as a means of predicting proliferation potential rather than assessing the system as a whole, ignoring the ability to enhance mitigating factors and manage, rather just establish the presence of, the threat. While the information garnered through these forms of analysis is necessary, it remains incomplete. By incorporating political, social, economic and technical capabilities as well as human factors such as intent into a single, multi-faceted risk management model, proliferation risk can be evaluated more effectively. Framing this information around how to improve and expand the Regime already in place and establishing where there are gaps in the system allows for a more complete approach to risk management, mitigation and resource allocation. The research conducted here seeks to combine all three elements (intent, capability and opportunity) in a comprehensive evaluation which incorporates an assessment of state-level variables, possible proliferation pathways and technical capability. Each portion of the analysis is carried out independently then combined to illustrate the full scope of a State's nuclear infrastructure while showing areas of weakness in the institutional framework.

  11. Analysis of pastoralists' perception on challenges and opportunities for sheep and goat production in Northern Kenya.

    Science.gov (United States)

    Abdilatif, Mohamed Haji; Onono, Joshua Orungo; Mutua, Florence Kanini

    2018-05-16

    Small ruminants' production contributes to livelihood of pastoral communities, but this faces myriad constraints. This study aimed at identifying challenges facing producers of small ruminants, prioritizing diseases and their control measures and documenting opportunities for improvement. Sixteen focus group discussions with livestock owners and 13 key informant interviews were done in selected areas in Mandera County, Northern Kenya, and both quantitative and qualitative data collected using a questionnaire guide. Occurrences of diseases (27.4%) and drought (25%) were consistently ranked high in all groups. Other production challenges included increased predation of livestock, inadequate delivery of veterinary services, and increased livestock mortalities. Peste des Petit ruminants was ranked high with a median rank of 21.5%, while contagious caprine pleuropneumonia and sheep and goat pox were ranked second and third, respectively. Other diseases included tick-borne diseases, helminthosis, and pneumonia. Vaccination was ranked as the most effective control strategy for infectious diseases. Other control measures included recitation of Quran and cauterization. However, several opportunities exist for support of small ruminants' production: increased budgetary allocation for disease control by government, initiation of projects that enhance livestock production in the region by government and its development partners. These findings are useful for policy makers for disease control and organizations that are working on projects that focuses on enhancement of pastoralists' resilience, while future research could also identify appropriate technologies that reduces these impacts.

  12. Analysis of near-term production and market opportunities for hydrogen and related activities

    Energy Technology Data Exchange (ETDEWEB)

    Mauro, R.; Leach, S. [National Hydrogen Association, Washington, DC (United States)

    1995-09-01

    This paper summarizes current and planned activities in the areas of hydrogen production and use, near-term venture opportunities, and codes and standards. The rationale for these efforts is to assess industry interest and engage in activities that move hydrogen technologies down the path to commercialization. Some of the work presented in this document is a condensed, preliminary version of reports being prepared under the DOE/NREL contract. In addition, the NHA work funded by Westinghouse Savannah River Corporation (WSRC) to explore the opportunities and industry interest in a Hydrogen Research Center is briefly described. Finally, the planned support of and industry input to the Hydrogen Technical Advisory Panel (HTAP) on hydrogen demonstration projects is discussed.

  13. Managerial Opportunism: Monitoring Financial Risk of Malaysian Shariah-compliant Companies

    Directory of Open Access Journals (Sweden)

    Aziatul Waznah Ghazali

    2018-01-01

    Full Text Available Managerial opportunism, such as earnings management, is a rampant, but often discreet, among certain managers. Agency theory and the notion of conflict of interest are used as bases to assume that managers would resolve to engage with inappropriate activities for their personal benefits. Distortion of earnings would erode investor confidence and is detrimental to the capital market. The Islamic capital market with Shariah-compliant firms is expected not to engage in activities that go against the religion code of conduct. The main purpose of this study is to investigate managerial opportunism among Shariah-compliant companies, specifically the relationship between real earnings management and the risk of financial distress, leverage, and free cash flow. This study employs 4,115 data from 694 sample companies for five years (2009–2013. Findings conclude that the risk of financial distress, leverage, and free cash flow have a significant relationship with earnings management among Shariah-compliant companies. This study provides evidence that further improvements on corporate governance are necessary to ensure that Shariah-compliant companies adhere with the Shariah requirement.

  14. Prehospital Blood Product Administration Opportunities in Ground Transport ALS EMS - A Descriptive Study.

    Science.gov (United States)

    Mix, Felicia M; Zielinski, Martin D; Myers, Lucas A; Berns, Kathy S; Luke, Anurahda; Stubbs, James R; Zietlow, Scott P; Jenkins, Donald H; Sztajnkrycer, Matthew D

    2018-06-01

    IntroductionHemorrhage remains the major cause of preventable death after trauma. Recent data suggest that earlier blood product administration may improve outcomes. The purpose of this study was to determine whether opportunities exist for blood product transfusion by ground Emergency Medical Services (EMS). This was a single EMS agency retrospective study of ground and helicopter responses from January 1, 2011 through December 31, 2015 for adult trauma patients transported from the scene of injury who met predetermined hemodynamic (HD) parameters for potential transfusion (heart rate [HR]≥120 and/or systolic blood pressure [SBP]≤90). A total of 7,900 scene trauma ground transports occurred during the study period. Of 420 patients meeting HD criteria for transfusion, 53 (12.6%) had a significant mechanism of injury (MOI). Outcome data were available for 51 patients; 17 received blood products during their emergency department (ED) resuscitation. The percentage of patients receiving blood products based upon HD criteria ranged from 1.0% (HR) to 5.9% (SBP) to 38.1% (HR+SBP). In all, 74 Helicopter EMS (HEMS) transports met HD criteria for blood transfusion, of which, 28 patients received prehospital blood transfusion. Statistically significant total patient care time differences were noted for both the HR and the SBP cohorts, with HEMS having longer time intervals; no statistically significant difference in mean total patient care time was noted in the HR+SBP cohort. In this study population, HD parameters alone did not predict need for ED blood product administration. Despite longer transport times, only one-third of HEMS patients meeting HD criteria for blood administration received prehospital transfusion. While one-third of ground Advanced Life Support (ALS) transport patients manifesting HD compromise received blood products in the ED, this represented 0.2% of total trauma transports over the study period. Given complex logistical issues involved in

  15. Grain production trends in Russia, Ukraine and Kazakhstan: New opportunities in an increasingly unstable world?

    Science.gov (United States)

    Lioubimtseva, Elena; Henebry, Geoffrey M.

    2012-06-01

    Grain production in the countries of the former USSR sharply declined during the past two decades and has only recently started to recover. In the context of the current economic and food-price crisis, Russia, Ukraine, and Kazakhstan might be presented with a window of opportunity to reemerge on the global agricultural market, if they succeed in increasing their productivity. The future of their agriculture, however, is highly sensitive to a combination of internal and external factors, such as institutional changes, land-use changes, climate variability and change, and global economic trends. The future of this region's grain production is likely to have a significant impact on the global and regional food security over the next decades.

  16. 76 FR 34639 - Funding Opportunity Title: Risk Management Education and Outreach Partnerships Program...

    Science.gov (United States)

    2011-06-14

    ... Succession Planning; Marketing: Marketing Strategies; Farm Products Branding; Farmers Markets; Financial: Financial Tools and Planning; Farm Management Strategies; Human: Farm Labor; Farm Safety; Food Safety, Risk... plans and strategies; and 4. Assist producers, farmers and ranchers in deciding on and implementing a...

  17. The risk of recurrent thromboembolic disorders in patients with unprovoked venous thromboembolism: new scenarios and opportunities.

    Science.gov (United States)

    Prandoni, Paolo; Barbar, Sofia; Milan, Marta; Vedovetto, Valentina; Pesavento, Raffaele

    2014-01-01

    The risk of recurrent thromboembolic disorders in the 10-year period following an episode of unprovoked venous thromboembolism (VTE) ranges between 30 and 50%, the rate being higher in patients with primary deep venous thrombosis (DVT) than in those with primary pulmonary embolism (PE). The clinical presentation with primary PE increases by more than three times the risk of a new PE episode over that with isolated DVT. Baseline parameters that increase this risk are the proximal location of DVT, obesity, old age and male sex, whereas the role of thrombophilia is controversial. An increasing role is played by post-baseline parameters such as the ultrasound assessment of residual vein thrombosis and the determination of D-dimer. While the latest international guidelines suggest indefinite anticoagulation for most patients with the first episode of unprovoked VTE, new scenarios are being offered by the identification of risk stratification models and by strategies that have the potential to help identify patients in whom anticoagulation can be safely discontinued, such as those that incorporate the assessment of D-dimer and residual vein thrombosis. New opportunities are being offered by low-dose aspirin, which has recently been reported to decrease by more than 30% the risk of recurrent events without increasing the bleeding risk; and especially by a few emerging anti-Xa and anti-IIa oral compounds, which are likely to induce fewer haemorrhagic complications than vitamin K antagonists while preserving at least the same effectiveness, do not require laboratory monitoring, and can be used immediately after the thrombotic episode. © 2013.

  18. Opportunities for Local for Local Food Production: A Case in the Dutch Fruit and Vegetables

    Directory of Open Access Journals (Sweden)

    Jurriaan Visser

    2013-03-01

    Full Text Available This paper investigates the opportunities for farmers to produce for local consumers, based on a case study in the Dutch horticulture sector. Main requirements for the set-up of a local chain of supply chain actors are investigated. Producer requirements are added value, availability of time, infrastructure and training. Retailer requirements are quality of food, purchasing volumes, food safety, communication to consumers and traceability of products. For consumers taste/freshness, sustainability, health benefits and authenticity are important attributes of local foods. Based on literature review and interviews with stakeholders four possible strategies for local food chains are defined. The ‘keep it local’ strategy means that the local food supply chains will not make use of the current infrastructure of the marketing coop that acts as chain coordinator. Deliveries are directly between farmer and retail outlet. The local products - conventional supply chain strategy implies that current (non-local supply chains are used to distribute local products. The supply chain planning will be more complex since products need to be separated per grower and distributed to several local supermarkets. In the ‘enabling producers’ strategy the marketing coop/chain coordinator is going to enable its member producers to sell their products locally. The marketing coop can support producers in for instance, billing and payments, marketing, logistics. The fourth strategy aims at strengthening current consumer communication strategies. It is argued that connecting producers and consumers, regardless of where they live is advantageous.Conclusion is that strategy 3; ‘Enabling producers’, in combination with strategy 4; ‘Strengthening current consumer communication strategies’ are the most promising options in setting up local food supply chains. Strategies 1 and 2, where the marketing coop/chain coordinator itself takes on the challenge of setting up

  19. Characterising agrometeorological climate risks and uncertainties: Crop production in Uganda

    DEFF Research Database (Denmark)

    Mubiru, Drake N.; Komutunga, Everline; Agona, Ambrose

    2012-01-01

    , the number of rainy days during this critical period of crop growth is decreasing, which possibly means that crops grown in this season are prone to climatic risks and therefore in need of appropriate adaptation measures. A time-series analysis of the maximum daily temperature clearly revealed an increase......Uganda is vulnerable to climate change as most of its agriculture is rain-fed; agriculture is also the backbone of the economy, and the livelihoods of many people depend upon it. Variability in rainfall may be reflected in the productivity of agricultural systems and pronounced variability may...... in temperature, with the lower limits of the ranges of daily maximums increasing faster than the upper limits. Finally, this study has generated information on seasonal rainfall characteristics that will be vital in exploiting the possibilities offered by climatic variability and also offers opportunities...

  20. Neurosurgery and Telemedicine in the United States: Assessment of the Risks and Opportunities.

    Science.gov (United States)

    Kahn, Elyne N; La Marca, Frank; Mazzola, Catherine A

    2016-05-01

    Telemedicine has seen substantial growth in the past 20 years, related to technologic advancements and evolving reimbursement policies. The risks and opportunities of neurosurgical telemedicine are nuanced. We reviewed general and peer-reviewed literature as it relates to telemedicine and neurosurgery, with particular attention to best practices, relevant state and federal policy conditions, economic evaluations, and prospective clinical studies. Despite technologic development, growing interest, and increasing reimbursement opportunities, telemedicine's utilization remains limited because of concerns regarding an apparent lack of need for telemedicine services, lack of widespread reimbursement, lack of interstate licensure reciprocity, lack of universal access to necessary technology, concerns about maintaining patient confidentiality, and concerns and limited precedent regarding liability issues. The Veterans Health Administration, a component of the U.S. Department of Veterans Affairs, represents a setting in which these concerns can be largely obviated and is a model for telemedicine best practices. Results from the VA demonstrate substantial cost savings and patient satisfaction with remote care for chronic neurologic conditions. Overall, the economic and clinical benefits of telemedicine will likely come from 1) diminished travel times and lost work time for patients; 2) remote consultation of subspecialty experts, such as neurosurgeons; and 3) remote consultation to assist with triage and care in time-sensitive scenarios, including acute stroke care and "teletrauma." Telemedicine is effective in many health care scenarios and will become more relevant to neurosurgical patient care. We favor proceeding with legislation to reduce barriers to telemedicine's growth. Copyright © 2016 Elsevier Inc. All rights reserved.

  1. An opportunity to combat obesity lies in the at-risk college population.

    Science.gov (United States)

    Swanson, Wendi Mortimer

    2016-04-01

    Approximately 70% of United States [or U.S.] adults are either overweight or obese. Obesity increases the risk of chronic disease and strains healthcare access, quality, and cost. Weight gain occurs in college students threatening optimal weight maintenance. Physical activity is fundamental to preventing disease. College students incur multiple challenges in weight management. The purpose of the article is to describe the opportunity for Advanced Practice Registered Nurses (APRNs) to intentionally become wellness promoters. The literature was reviewed and interventions developed. Guided by Bandura's Social Cognitive Theory, focus was concentrated on environmental influences through a proposed Staying Active Campaign (SAC). College students are a vulnerable population at risk for unhealthful practices. Young adulthood is a critical period of weight gain that carries risk for later adulthood. College students desire and require assistance for successful weight management. Interventions can be directed by APRNs to achieve healthful weight management and create a campus-wide culture that reinforces healthful practices. Obesity in the college population is a twofold circumstance. Action by APRNs is needed to address obesity and advocate for the prevention of future obesity. The SAC decreases the confounding college environment and supports the students' ability to be physically active while establishing personal lifelong behaviors to emulate and share with others. ©2016 American Association of Nurse Practitioners.

  2. Biodiesel biorefinery: opportunities and challenges for microbial production of fuels and chemicals from glycerol waste.

    Science.gov (United States)

    Almeida, João R M; Fávaro, Léia C L; Quirino, Betania F

    2012-07-18

    The considerable increase in biodiesel production worldwide in the last 5 years resulted in a stoichiometric increased coproduction of crude glycerol. As an excess of crude glycerol has been produced, its value on market was reduced and it is becoming a "waste-stream" instead of a valuable "coproduct". The development of biorefineries, i.e. production of chemicals and power integrated with conversion processes of biomass into biofuels, has been singled out as a way to achieve economically viable production chains, valorize residues and coproducts, and reduce industrial waste disposal. In this sense, several alternatives aimed at the use of crude glycerol to produce fuels and chemicals by microbial fermentation have been evaluated. This review summarizes different strategies employed to produce biofuels and chemicals (1,3-propanediol, 2,3-butanediol, ethanol, n-butanol, organic acids, polyols and others) by microbial fermentation of glycerol. Initially, the industrial use of each chemical is briefly presented; then we systematically summarize and discuss the different strategies to produce each chemical, including selection and genetic engineering of producers, and optimization of process conditions to improve yield and productivity. Finally, the impact of the developments obtained until now are placed in perspective and opportunities and challenges for using crude glycerol to the development of biodiesel-based biorefineries are considered. In conclusion, the microbial fermentation of glycerol represents a remarkable alternative to add value to the biodiesel production chain helping the development of biorefineries, which will allow this biofuel to be more competitive.

  3. BUSINESS OPPORTUNITIES OF CITRIC ACID PRODUCTION BY FERMENTATION FROM SUGAR SUBSTRATES IN CUBA

    Directory of Open Access Journals (Sweden)

    Omar Pérez Navarro

    2016-04-01

    Full Text Available A proposal for opportunities of citric acid production in Cuba, using sources of sugar substrates such as refined sugar, molasses and whey, by submerged fermentation with Aspergillus niger, where a technology is established from the selected substrate which is provided and the microorganism used. This is a demanding process in terms of investment costs and operation where the best combinations of productivity and cost are achieved with molasses followed by refined sugar and whey. For the selected substrate, the mass and energy balance in each of the steps in the process of obtaining citric acid for different productive capacities of citric acid was made and the minimum economic size of 2.5 t / day was determined. A production capacity of 8 t / day of granulated acid (2 640 t / a, with estimated total investment of $ 9,068,713, NPV = $ 1,401,561, IRR = 27% and DPP = 3 years was selected. The project is resistant to the rising price of raw materials and the cost of electricity and is favored when the process is integrated into a sugar mill cogeneration, while it is sensitive to a reduction in the selling price of the product.

  4. Accounting for forest carbon pool dynamics in product carbon footprints: Challenges and opportunities

    International Nuclear Information System (INIS)

    Newell, Joshua P.; Vos, Robert O.

    2012-01-01

    Modification and loss of forests due to natural and anthropogenic disturbance contribute an estimated 20% of annual greenhouse gas (GHG) emissions worldwide. Although forest carbon pool modeling rarely suggests a ‘carbon neutral’ flux profile, the life cycle assessment community and associated product carbon footprint protocols have struggled to account for the GHG emissions associated with forestry, specifically, and land use generally. Principally, this is due to underdeveloped linkages between life cycle inventory (LCI) modeling for wood and forest carbon modeling for a full range of forest types and harvest practices, as well as a lack of transparency in globalized forest supply chains. In this paper, through a comparative study of U.S. and Chinese coated freesheet paper, we develop the initial foundations for a methodology that rescales IPCC methods from the national to the product level, with reference to the approaches in three international product carbon footprint protocols. Due to differences in geographic origin of the wood fiber, the results for two scenarios are highly divergent. This suggests that both wood LCI models and the protocols need further development to capture the range of spatial and temporal dimensions for supply chains (and the associated land use change and modification) for specific product systems. The paper concludes by outlining opportunities to measure and reduce uncertainty in accounting for net emissions of biogenic carbon from forestland, where timber is harvested for consumer products. - Highlights: ► Typical life cycle assessment practice for consumer products often excludes significant land use change emissions when estimating carbon footprints. ► The article provides a methodology to rescale IPCC guidelines for product-level carbon footprints. ► Life cycle inventories and product carbon footprint protocols need more comprehensive land use-related accounting. ► Interdisciplinary collaboration linking the LCA and

  5. [Solar protection products: efficacy and risks].

    Science.gov (United States)

    Beani, J-C

    2012-04-01

    Solar protection products (SPP) containing chemical filters and/or mineral filters are extensively used today in photoprotection; however, concerns continue to be voiced about their efficacy and about their possible dangers. A rapid review of photoprotection strategies shows that SPP owe their photoprotective effect to the absence of other photoprotection methods having clearly established efficacy in healthy subjects; in addition, they exhibit real protective efficacy against the majority of harmful effects of solar radiation, provided they have been devised in keeping with the specifications clearly set out in the recommendations of the French Medicines Agency (Afssaps). Such efficacy is dependent on their correct usage, recently reiterated by Afssaps in its recommendations to end-users concerning the good use of solar products: application of adequate quantities of such products, selection of the appropriate photoprotection class based on phototype and conditions of exposure, and regular renewal of applications in the event of prolonged exposure and after bathing or profuse sweating. Solar filters have long been known to cause contact allergic dermatitis, irritative dermatitis and photosensitisation, and a particular risk has appeared with the use of octocrylene. However, debate has centred primarily on the risk of endocrine disturbance potentially induced by chemical filters, certain of which exhibit established transcutaneous penetration. The risk of mimicry of an effect of oestradiol has been raised on the basis of a series of studies, almost all of which were carried out by the same team, and which mainly concerned 4-methylbenzylidene-camphor (4-MBC) following oral absorption in the rat. The risk of this type of effect with SPPs under normal conditions of use seems fairly remote according to the current state of knowledge; in any event, within the context of the "National Fertility Action Plan", Afssaps has been formally requested to analyse the risk

  6. Bio-based fuels: an analysis of potential, conditions, market, instruments and risks. Opportunities and risks - the BIODRIV project. Final Report; Biobaserade drivmedel: analys av potential, foerutsaettningar, marknad, styrmedel och risker. Moejligheter och risker - projektet BIODRIV. Slutrapport

    Energy Technology Data Exchange (ETDEWEB)

    Rydberg, Tomas (IVL Svenska Miljoeinstitutet, Stockholm (Sweden)); Gaardfeldt, Katarina; Ahlbaeck, Anders (Goeteborgs Miljoevetenskapliga Centrum, Chalmers Tekniska Hoegskola och Goeteborgs Universitet (Sweden)) (and others)

    2010-12-15

    The BIODRIV project is a study of the conditions, opportunities, constraints and risks in the short and long term for the Swedish production of biofuels, with specific focus on the production opportunities offered by the Swedish refineries. The study was conducted at Chalmers Univ. of Technology and IVL Swedish Environmental Research Inst. with support from Preem Environment Foundation and the Foundation of IVL. Researchers in the disciplines of environmental economics, chemical engineering and environmental system analysis have been working collectively to illustrate various technology tracks for bio-based fuel production. A total of six technology tracks for biofuel production have been identified in the long run, in whole or in part, which can replace today's fossil-based fuels in the transport sector. The six technology tracks are: methane from gas networks, decentralized pyrolysis/gasification, different resource bases to fat, hydrogen, methanol, electricity

  7. Phage Therapy Approaches to Reducing Pathogen Persistence and Transmission in Animal Production Environments: Opportunities and Challenges.

    Science.gov (United States)

    Colavecchio, Anna; Goodridge, Lawrence D

    2017-06-01

    The era of genomics has allowed for characterization of phages for use as antimicrobials to treat animal infections with a level of precision never before realized. As more research in phage therapy has been conducted, several advantages of phage therapy have been realized, including the ubiquitous nature, specificity, prevalence in the biosphere, and low inherent toxicity of phages, which makes them a safe and sustainable technology for control of animal diseases. These unique qualities of phages have led to several opportunities with respect to emerging trends in infectious disease treatment. However, the opportunities are tempered by several challenges to the successful implementation of phage therapy, such as the fact that an individual phage can only infect one or a few bacterial strains, meaning that large numbers of different phages will likely be needed to treat infections caused by multiple species of bacteria. In addition, phages are only effective if enough of them can reach the site of bacterial colonization, but clearance by the immune system upon introduction to the animal is a reality that must be overcome. Finally, bacterial resistance to the phages may develop, resulting in treatment failure. Even a successful phage infection and lysis of its host has consequences, because large amounts of endotoxin are released upon lysis of Gram-negative bacteria, which can lead to local and systemic complications. Overcoming these challenges will require careful design and development of phage cocktails, including comprehensive characterization of phage host range and assessment of immunological risks associated with phage treatment.

  8. Bookending the Opportunity to Lower Wind’s LCOE by Reducing the Uncertainty Surrounding Annual Energy Production

    Energy Technology Data Exchange (ETDEWEB)

    Bolinger, Mark [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States). Energy Analysis and Environmental Impacts Div.

    2017-06-01

    Reducing the performance risk surrounding a wind project can potentially lead to a lower weighted-average cost of capital (WACC), and hence a lower levelized cost of energy (LCOE), through an advantageous shift in capital structure, and possibly also a reduction in the cost of capital. Specifically, a reduction in performance risk will move the 1-year P99 annual energy production (AEP) estimate closer to the P50 AEP estimate, which in turn reduces the minimum debt service coverage ratio (DSCR) required by lenders, thereby allowing the project to be financed with a greater proportion of low-cost debt. In addition, a reduction in performance risk might also reduce the cost of one or more of the three sources of capital that are commonly used to finance wind projects: sponsor or cash equity, tax equity, and/or debt. Preliminary internal LBNL analysis of the maximum possible LCOE reduction attainable from reducing the performance risk of a wind project found a potentially significant opportunity for LCOE reduction of ~$10/MWh, by reducing the P50 DSCR to its theoretical minimum value of 1.0 (Bolinger 2015b, 2014) and by reducing the cost of sponsor equity and debt by one-third to one-half each (Bolinger 2015a, 2015b). However, with FY17 funding from the U.S. Department of Energy’s Atmosphere to Electrons (A2e) Performance Risk, Uncertainty, and Finance (PRUF) initiative, LBNL has been revisiting this “bookending” exercise in more depth, and now believes that its earlier preliminary assessment of the LCOE reduction opportunity was overstated. This reassessment is based on two new-found understandings: (1) Due to ever-present and largely irreducible inter-annual variability (IAV) in the wind resource, the minimum required DSCR cannot possibly fall to 1.0 (on a P50 basis), and (2) A reduction in AEP uncertainty will not necessarily lead to a reduction in the cost of capital, meaning that a shift in capital structure is perhaps the best that can be expected (perhaps

  9. Industrial-strength ecology: trade-offs and opportunities in algal biofuel production.

    Science.gov (United States)

    Shurin, Jonathan B; Abbott, Rachel L; Deal, Michael S; Kwan, Garfield T; Litchman, Elena; McBride, Robert C; Mandal, Shovon; Smith, Val H

    2013-11-01

    Microalgae represent one of the most promising groups of candidate organisms for replacing fossil fuels with contemporary primary production as a renewable source of energy. Algae can produce many times more biomass per unit area than terrestrial crop plants, easing the competing demands for land with food crops and native ecosystems. However, several aspects of algal biology present unique challenges to the industrial-scale aquaculture of photosynthetic microorganisms. These include high susceptibility to invading aquatic consumers and weeds, as well as prodigious requirements for nutrients that may compete with the fertiliser demands of other crops. Most research on algal biofuel technologies approaches these problems from a cellular or genetic perspective, attempting either to engineer or select algal strains with particular traits. However, inherent functional trade-offs may limit the capacity of genetic selection or synthetic biology to simultaneously optimise multiple functional traits for biofuel productivity and resilience. We argue that a community engineering approach that manages microalgal diversity, species composition and environmental conditions may lead to more robust and productive biofuel ecosystems. We review evidence for trade-offs, challenges and opportunities in algal biofuel cultivation with a goal of guiding research towards intensifying bioenergy production using established principles of community and ecosystem ecology. © 2013 John Wiley & Sons Ltd/CNRS.

  10. "Omics" of maize stress response for sustainable food production: opportunities and challenges.

    Science.gov (United States)

    Gong, Fangping; Yang, Le; Tai, Fuju; Hu, Xiuli; Wang, Wei

    2014-12-01

    Maize originated in the highlands of Mexico approximately 8700 years ago and is one of the most commonly grown cereal crops worldwide, followed by wheat and rice. Abiotic stresses (primarily drought, salinity, and high and low temperatures), together with biotic stresses (primarily fungi, viruses, and pests), negatively affect maize growth, development, and eventually production. To understand the response of maize to abiotic and biotic stresses and its mechanism of stress tolerance, high-throughput omics approaches have been used in maize stress studies. Integrated omics approaches are crucial for dissecting the temporal and spatial system-level changes that occur in maize under various stresses. In this comprehensive analysis, we review the primary types of stresses that threaten sustainable maize production; underscore the recent advances in maize stress omics, especially proteomics; and discuss the opportunities, challenges, and future directions of maize stress omics, with a view to sustainable food production. The knowledge gained from studying maize stress omics is instrumental for improving maize to cope with various stresses and to meet the food demands of the exponentially growing global population. Omics systems science offers actionable potential solutions for sustainable food production, and we present maize as a notable case study.

  11. Opportunities for multivariate analysis of open spatial datasets to characterize urban flooding risks

    Directory of Open Access Journals (Sweden)

    S. Gaitan

    2015-06-01

    Full Text Available Cities worldwide are challenged by increasing urban flood risks. Precise and realistic measures are required to reduce flooding impacts. However, currently implemented sewer and topographic models do not provide realistic predictions of local flooding occurrence during heavy rain events. Assessing other factors such as spatially distributed rainfall, socioeconomic characteristics, and social sensing, may help to explain probability and impacts of urban flooding. Several spatial datasets have been recently made available in the Netherlands, including rainfall-related incident reports made by citizens, spatially distributed rain depths, semidistributed socioeconomic information, and buildings age. Inspecting the potential of this data to explain the occurrence of rainfall related incidents has not been done yet. Multivariate analysis tools for describing communities and environmental patterns have been previously developed and used in the field of study of ecology. The objective of this paper is to outline opportunities for these tools to explore urban flooding risks patterns in the mentioned datasets. To that end, a cluster analysis is performed. Results indicate that incidence of rainfall-related impacts is higher in areas characterized by older infrastructure and higher population density.

  12. Opportunities for multivariate analysis of open spatial datasets to characterize urban flooding risks

    Science.gov (United States)

    Gaitan, S.; ten Veldhuis, J. A. E.

    2015-06-01

    Cities worldwide are challenged by increasing urban flood risks. Precise and realistic measures are required to reduce flooding impacts. However, currently implemented sewer and topographic models do not provide realistic predictions of local flooding occurrence during heavy rain events. Assessing other factors such as spatially distributed rainfall, socioeconomic characteristics, and social sensing, may help to explain probability and impacts of urban flooding. Several spatial datasets have been recently made available in the Netherlands, including rainfall-related incident reports made by citizens, spatially distributed rain depths, semidistributed socioeconomic information, and buildings age. Inspecting the potential of this data to explain the occurrence of rainfall related incidents has not been done yet. Multivariate analysis tools for describing communities and environmental patterns have been previously developed and used in the field of study of ecology. The objective of this paper is to outline opportunities for these tools to explore urban flooding risks patterns in the mentioned datasets. To that end, a cluster analysis is performed. Results indicate that incidence of rainfall-related impacts is higher in areas characterized by older infrastructure and higher population density.

  13. A Study on Correlation of Risk-Taking and the Oral Production of English Majors in China

    Science.gov (United States)

    Wang, Yang; Lin, Yuewu

    2015-01-01

    Risk-taking refers to the tendency to engage in behaviors that have the potential to be harmful or dangerous, yet at the same time provides the opportunity for some kinds of outcome that can be perceived as positive. Ely (1986) and Bang (1999) have mentioned the relationship between risk-taking and oral production in the process of English…

  14. Integration of microalgae cultivation with industrial waste remediation for biofuel and bioenergy production: opportunities and limitations.

    Science.gov (United States)

    McGinn, Patrick J; Dickinson, Kathryn E; Bhatti, Shabana; Frigon, Jean-Claude; Guiot, Serge R; O'Leary, Stephen J B

    2011-09-01

    There is currently a renewed interest in developing microalgae as a source of renewable energy and fuel. Microalgae hold great potential as a source of biomass for the production of energy and fungible liquid transportation fuels. However, the technologies required for large-scale cultivation, processing, and conversion of microalgal biomass to energy products are underdeveloped. Microalgae offer several advantages over traditional 'first-generation' biofuels crops like corn: these include superior biomass productivity, the ability to grow on poor-quality land unsuitable for agriculture, and the potential for sustainable growth by extracting macro- and micronutrients from wastewater and industrial flue-stack emissions. Integrating microalgal cultivation with municipal wastewater treatment and industrial CO(2) emissions from coal-fired power plants is a potential strategy to produce large quantities of biomass, and represents an opportunity to develop, test, and optimize the necessary technologies to make microalgal biofuels more cost-effective and efficient. However, many constraints on the eventual deployment of this technology must be taken into consideration and mitigating strategies developed before large scale microalgal cultivation can become a reality. As a strategy for CO(2) biomitigation from industrial point source emitters, microalgal cultivation can be limited by the availability of land, light, and other nutrients like N and P. Effective removal of N and P from municipal wastewater is limited by the processing capacity of available microalgal cultivation systems. Strategies to mitigate against the constraints are discussed.

  15. Production and processing of fuel by the forest industry - opportunities and conditions

    International Nuclear Information System (INIS)

    Magnusson, L.

    1991-01-01

    The purpose of this study was to illustrate the opportunities for the forest industry to establish a system of handling and processing biofuels in conjunction with their existing activities, and which would supply a future market for biofuels in, for example, electricity generation. The sawmills report that it is difficult today to find a market for fuel products, especially for sawmills at greater distances from larger biofuel-consuming plants. The sawmills show great interest in cogeneration in their own plants, but report difficulties in achieving profitability. The main problem is reported to be that the price of the surplus electricity delivered to the grid is too low, but also that the electricity prices today are so low that it is difficult to justify even generating electricity for the mill's own use. There is an interest in the paper and pulp industry for integrated methods and production of biofuels since the part-tree methods used, at least in some parts of Sweden, are considered to contribute also to an increase in the availability of pulp wood to the industry. A fundamental viewpoint is, however, that the plants are built for the primary purpose of producing pulp or paper. It is unlikely that the industry would give priority to investments for production of a new secondary product in the form of fuel products, particularly when the conditions today imply that there are few possibilities to achieve any particular profitability. The most probable solution is that the fuel is processed outside the industry by other parties, e.g., the forest divisions. In the long term, increased efficiency in the processes may lead to a primary heat surplus which could be used to produce processed fuels

  16. Biodiesel biorefinery: opportunities and challenges for microbial production of fuels and chemicals from glycerol waste

    Directory of Open Access Journals (Sweden)

    Almeida João R M

    2012-07-01

    Full Text Available Abstract The considerable increase in biodiesel production worldwide in the last 5 years resulted in a stoichiometric increased coproduction of crude glycerol. As an excess of crude glycerol has been produced, its value on market was reduced and it is becoming a “waste-stream” instead of a valuable “coproduct”. The development of biorefineries, i.e. production of chemicals and power integrated with conversion processes of biomass into biofuels, has been singled out as a way to achieve economically viable production chains, valorize residues and coproducts, and reduce industrial waste disposal. In this sense, several alternatives aimed at the use of crude glycerol to produce fuels and chemicals by microbial fermentation have been evaluated. This review summarizes different strategies employed to produce biofuels and chemicals (1,3-propanediol, 2,3-butanediol, ethanol, n-butanol, organic acids, polyols and others by microbial fermentation of glycerol. Initially, the industrial use of each chemical is briefly presented; then we systematically summarize and discuss the different strategies to produce each chemical, including selection and genetic engineering of producers, and optimization of process conditions to improve yield and productivity. Finally, the impact of the developments obtained until now are placed in perspective and opportunities and challenges for using crude glycerol to the development of biodiesel-based biorefineries are considered. In conclusion, the microbial fermentation of glycerol represents a remarkable alternative to add value to the biodiesel production chain helping the development of biorefineries, which will allow this biofuel to be more competitive.

  17. Domestic market opportunities for Alaska lumber-species preferences by secondary wood products manufacturers in the continental United States.

    Science.gov (United States)

    Joseph Roos; David L. Nicholls

    2006-01-01

    New equipment, technology, and marketing efforts have allowed Alaska’s wood products producers to consider opportunities previously unavailable to them. Until recently, the primary product produced by Alaska firms was rough, unseasoned lumber sold primarily within local markets. Given the purchase and installation of new drying and planing equipment, Alaska producers...

  18. Excipient Usage Technical Risk Assessment for Generic Solid Dose Products

    Directory of Open Access Journals (Sweden)

    Ajay Babu Pazhayattil

    2017-09-01

    Full Text Available This paper proposes an assessment methodology for solid dose generic small molecule drug products. It addresses the ‘usage of the excipient’ portion of the trinomial by utilizing the systematic approach of Risk Identification, Risk Analysis and Risk Evaluation as per ICH Q9 Quality Risk Management outlined for developing risk control strategies. The assessment and maintenance of excipient risk profile is essential to minimize any potential risk associated to excipients impacting patients.

  19. Assessment of weather risk on chestnut production

    Science.gov (United States)

    Pereira, M. G.; Gomes-Laranjo, J.; Caramelo, L.

    2009-04-01

    to March) precipitation, the number of days with maximum temperature between 24°C and 28°C and the number of days of May with minimum temperature below 0°C is able to model the chestnut productivity with r2 equal to 0.79. It should be pointed out that the relation between weather/climate and chestnut productivity may change over time. Finally, it is important to express objectively the effects of temperature and precipitation extremes on the chestnut productivity since temperature is one of the global circulation models predicted variables with less uncertainty. With these tools will be possible to assess the weather related risk on chestnut production as well as infer about evolution of the adequate conditions to the chestnut trees in the actual plantations and about the expansion of this specie. Bounous, G. (2002) "Il castagno" [Chestnut.] - Edagricole, Bologna. [In Ital.] Gomes-Laranjo, J., Coutinho, J.P., Ferreira-Cardoso, J., Pimentel-Pereira, M., Ramos, C., Torres-Pereira, J.(2005) "Assessment to a new concept of chestnut orchard management in vegetative wall.". Acta Hort. 693: 707-712. Gomes-Laranjo, J.C.E., Peixoto, F., Wong Fong Sang, H.W., Torres-Pereira, J.M.G.(2006) "Study of the temperature effect in three chestnut (Castanea sativa Mill.) cultivars' behavior". J. Plant Physiol. 163: 945-955.

  20. Attention-Deficit/Hyperactivity Disorder and Risk of Substance Use Disorder: Developmental Considerations, Potential Pathways, and Opportunities for Research

    Science.gov (United States)

    Molina, Brooke S.G.; Pelham, William E.

    2014-01-01

    Many opportunities to explain ADHD-related risk of substance use/disorder (SUD) remain available for study. We detail these opportunities by considering characteristics of children with ADHD and factors affecting their outcomes side-by-side with overlapping variables in the developmental literature on SUD etiology. Although serious conduct problems are a known contributor to ADHD-related risk of SUD, few studies have considered their emergence developmentally and in relation to other candidate mediators and moderators that could also explain risk and be intervention targets. Common ADHD-related impairments, such as school difficulties, are in need of research. Heterogeneous social impairments have the potential for predisposing, and buffering, influences. Research on neurocognitive domains should move beyond standard executive function batteries to measure deficits in the interface between cognitive control, reward, and motivation. Ultimately, maximizing prediction will depend, as it has in the SUD literature, on simultaneous consideration of multiple risk factors. PMID:24437435

  1. Invited review: Enteric methane in dairy cattle production: quantifying the opportunities and impact of reducing emissions.

    Science.gov (United States)

    Knapp, J R; Laur, G L; Vadas, P A; Weiss, W P; Tricarico, J M

    2014-01-01

    Many opportunities exist to reduce enteric methane (CH4) and other greenhouse gas (GHG) emissions per unit of product from ruminant livestock. Research over the past century in genetics, animal health, microbiology, nutrition, and physiology has led to improvements in dairy production where intensively managed farms have GHG emissions as low as 1 kg of CO2 equivalents (CO2e)/kg of energy-corrected milk (ECM), compared with >7 kg of CO2 e/kg of ECM in extensive systems. The objectives of this review are to evaluate options that have been demonstrated to mitigate enteric CH4 emissions per unit of ECM (CH4/ECM) from dairy cattle on a quantitative basis and in a sustained manner and to integrate approaches in genetics, feeding and nutrition, physiology, and health to emphasize why herd productivity, not individual animal productivity, is important to environmental sustainability. A nutrition model based on carbohydrate digestion was used to evaluate the effect of feeding and nutrition strategies on CH4/ECM, and a meta-analysis was conducted to quantify the effects of lipid supplementation on CH4/ECM. A second model combining herd structure dynamics and production level was used to estimate the effect of genetic and management strategies that increase milk yield and reduce culling on CH4/ECM. Some of these approaches discussed require further research, but many could be implemented now. Past efforts in CH4 mitigation have largely focused on identifying and evaluating CH4 mitigation approaches based on nutrition, feeding, and modifications of rumen function. Nutrition and feeding approaches may be able to reduce CH4/ECM by 2.5 to 15%, whereas rumen modifiers have had very little success in terms of sustained CH4 reductions without compromising milk production. More significant reductions of 15 to 30% CH4/ECM can be achieved by combinations of genetic and management approaches, including improvements in heat abatement, disease and fertility management, performance

  2. The role of cocoa as a cigarette additive: opportunities for product regulation.

    Science.gov (United States)

    Sokol, Natasha A; Kennedy, Ryan David; Connolly, Gregory N

    2014-07-01

    The 2009 Family Smoking Prevention and Tobacco Control Act prohibited the use of characterizing flavors in cigarettes; however, some of these flavors are still used in cigarettes at varying levels. We reviewed tobacco industry internal documents to investigate the role of one of these flavors, cocoa, with the objective of understanding its relationship to sensory and risk perception, promotion of dependence, and enhancement of attractiveness and acceptability. We used the Legacy Tobacco Documents Library to identify documents relevant to our research questions. Initial search terms were generated following an examination of published literature on cocoa, other cigarette additives, and sensory and risk perception. Further research questions and search terms were generated based on review of documents generated from the initial search terms. Cocoa is widely applied to cigarettes and has been used by the tobacco industry as an additive since the early 20th century. Cocoa can alter the sensory properties of cigarette smoke, including by providing a more appealing taste and decreasing its harshness. The tobacco industry has experimented with manipulating cocoa levels as a means of achieving sensory properties that appeal to women and youth. Although cocoa is identified as a flavor on tobacco industry Web sites, it may serve other sensory purposes in cigarettes as well. Eliminating cocoa as an additive from tobacco products may affect tobacco product abuse liability by altering smokers' perceptions of product risk, and decreasing product appeal, especially among vulnerable populations. © The Author 2014. Published by Oxford University Press on behalf of the Society for Research on Nicotine and Tobacco. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  3. The mitigation of volcanic risk as opportunity for an ecological and resilient city

    Directory of Open Access Journals (Sweden)

    Giulio Zuccaro

    2014-05-01

    Full Text Available The paper outlines some of the results of SPeeD project, funded by EU, Campania Region and National Department of Civil Protection. The research is aimed at the definition of impact scenarios resulting from the eruption of Vesuvius and Campi Flegrei and the development of strategies to reduce the damage on the built environment. The issues related to the identification of technical solutions for mitigating the impact on buildings and infrastructure, to the socio-economic benefits arising from widespread interventions on the territory, as well as to the drafting of preparatory guidelines for the implementation of regional regulations and local building codes for volcanic risk-prone areas, have been developed at PLINIVS Study Centre of University of Naples Federico II. The methodological approach for the definition of appropriate technologies aimed at reducing the impact in relation to eruptive phenomena and construction types in the area is based on PLINIVS Volcanic Impact Simulation Model, a unique tool to define impact scenarios consequent to a volcanic eruption in the region, able to evaluate the cumulative effects given by the action of volcanic phenomena, such as earthquake, ash fall, pyroclastic flows and landslides. The study aims to demonstrate how the application of appropriate technologies for retrofit interventions or new constructions, aimed at reducing the vulnerability of building components, represents at the same time an opportunity to encourage a diffuse redevelopment of the territory driven by energy and environmental efficiency issues.

  4. Prenatal Stress as a Risk-and an Opportunity-Factor.

    Science.gov (United States)

    Hartman, Sarah; Freeman, Sara M; Bales, Karen L; Belsky, Jay

    2018-04-01

    Two separate lines of research indicate (a) that prenatal stress is associated with heightened behavioral and physiological reactivity and (b) that these postnatal phenotypes are associated with increased susceptibility to both positive and negative developmental experiences. Therefore, prenatal stress may increase sensitivity to the rearing environment. We tested this hypothesis by manipulating prenatal stress and rearing-environment quality, using a cross-fostering paradigm, in prairie voles. Results showed that prenatally stressed voles, as adults, displayed the highest behavioral and physiological reactivity when cross-fostered to low-contact (i.e., low-quality) rearing but the lowest behavioral and physiological reactivity when cross-fostered to high-contact (i.e., high-quality) rearing; non-prenatally stressed voles showed no effect of rearing condition. Additionally, while neither prenatal stress nor rearing condition affected oxytocin receptor binding, prenatally stressed voles cross-fostered to high-contact rearing showed the highest vasopressin-1a receptor binding in the amygdala. Results indicate that prenatal stress induces greater environmental sensitivity, making it both a risk and an opportunity factor.

  5. Child Sexual Abuse Prevention Opportunities: Parenting, Programs, and the Reduction of Risk.

    Science.gov (United States)

    Rudolph, Julia; Zimmer-Gembeck, Melanie J; Shanley, Dianne C; Hawkins, Russell

    2018-02-01

    To date, child sexual abuse (CSA) prevention has relied largely on child-focused education, teaching children how to identify, avoid, and disclose sexual abuse. The purpose of this article is to explore how prevention opportunities can include parents in new and innovative ways. We propose that parents can play a significant role as protectors of their children via two pathways: (i) directly, through the strong external barriers afforded by parent supervision, monitoring, and involvement; and (ii) indirectly, by promoting their children's self-efficacy, competence, well-being, and self-esteem, which the balance of evidence suggests will help them become less likely targets for abuse and more able to respond appropriately and disclose abuse if it occurs. In this article, we first describe why teaching young children about CSA protective behaviors might not be sufficient for prevention. We then narratively review the existing research on parents and prevention and the parenting and family circumstances that may increase a child's risk of experiencing sexual abuse. Finally, we make a number of recommendations for future approaches to prevention that may better inform and involve parents and other adult protectors in preventing CSA.

  6. Relay cropping as a sustainable approach: problems and opportunities for sustainable crop production.

    Science.gov (United States)

    Tanveer, Mohsin; Anjum, Shakeel Ahmad; Hussain, Saddam; Cerdà, Artemi; Ashraf, Umair

    2017-03-01

    Climate change, soil degradation, and depletion of natural resources are becoming the most prominent challenges for crop productivity and environmental sustainability in modern agriculture. In the scenario of conventional farming system, limited chances are available to cope with these issues. Relay cropping is a method of multiple cropping where one crop is seeded into standing second crop well before harvesting of second crop. Relay cropping may solve a number of conflicts such as inefficient use of available resources, controversies in sowing time, fertilizer application, and soil degradation. Relay cropping is a complex suite of different resource-efficient technologies, which possesses the capability to improve soil quality, to increase net return, to increase land equivalent ratio, and to control the weeds and pest infestation. The current review emphasized relay cropping as a tool for crop diversification and environmental sustainability with special focus on soil. Briefly, benefits, constraints, and opportunities of relay cropping keeping the goals of higher crop productivity and sustainability have also been discussed in this review. The research and knowledge gap in relay cropping was also highlighted in order to guide the further studies in future.

  7. Essential Drugs Production in Brazil, Russia, India, China and South Africa (BRICS: Opportunities and Challenges

    Directory of Open Access Journals (Sweden)

    Zoheir Ezziane

    2014-12-01

    Full Text Available The objective of this work is to elucidate various essential drugs in the Brazil, Russia, India, China and South Africa (BRICS countries. It discusses the opportunities and challenges of the existing biotech infrastructure and the production of drugs and vaccines in member states of the BRICS. This research is based on a systematic literature review between the years 2000 and 2014 of documents retrieved from the databases Embase, PubMed/Medline, Global Health, and Google Scholar, and the websites of relevant international organizations, research institutions and philanthropic organizations. Findings vary from one member state to another. These include useful comparison between the BRICS countries in terms of pharmaceuticals expenditure versus total health expenditure, local manufacturing of drugs/vaccines using technology and know-how transferred from developed countries, and biotech entrepreneurial collaborations under the umbrella of the BRICS region. This study concludes by providing recommendations to support more of inter collaborations among the BRICS countries as well as between BRICS and many developing countries to shrink drug production costs. In addition, this collaboration would also culminate in reaching out to poor countries that are not able to provide their communities and patients with cost-effective essential medicines.

  8. Fair opportunities, social productivity and wellbeing in disability: Towards a theoretical foundation.

    Science.gov (United States)

    Siegrist, Johannes; Fekete, Christine

    2016-06-13

    Theory-based approaches provide explanations of the impact of components of the International Classification of Functioning, Disability and Health (ICF) classification on outcomes such as health and wellbeing. Here, one such approach is proposed, focusing on social participation and its association with wellbeing. In addition to elaborating a theoretical approach, a narrative review of research on labour market participation of persons with severe disability, spinal cord injury, is conducted to illustrate the utility of the proposed approach. Availability and good quality of productive activities, in particular paid work, are expected to improve wellbeing by strengthening favourable experiences of personal control and social recognition. As these opportunities are restricted among persons with disabilities, conditions that enable full social participation need to be strengthened. Research identified several such conditions at the individual (e.g. coping, social support, educational skills) and the contextual socio-political level (e.g. quality of care, medical and vocational rehabilitation), although their potential of improving wellbeing has not yet been sufficiently explored. In conclusion, supplementing the established ICF classification by theory-based approaches may advance explanations of adverse effects of reduced functioning and wellbeing in disability. This new knowledge can guide the development of interventions to improve participation in general and social productivity in particular.

  9. Essential drugs production in Brazil, Russia, India, China and South Africa (BRICS): opportunities and challenges.

    Science.gov (United States)

    Ezziane, Zoheir

    2014-12-01

    The objective of this work is to elucidate various essential drugs in the Brazil, Russia, India, China and South Africa (BRICS) countries. It discusses the opportunities and challenges of the existing biotech infrastructure and the production of drugs and vaccines in member states of the BRICS. This research is based on a systematic literature review between the years 2000 and 2014 of documents retrieved from the databases Embase, PubMed/Medline, Global Health, and Google Scholar, and the websites of relevant international organizations, research institutions and philanthropic organizations. Findings vary from one member state to another. These include useful comparison between the BRICS countries in terms of pharmaceuticals expenditure versus total health expenditure, local manufacturing of drugs/vaccines using technology and know-how transferred from developed countries, and biotech entrepreneurial collaborations under the umbrella of the BRICS region. This study concludes by providing recommendations to support more of inter collaborations among the BRICS countries as well as between BRICS and many developing countries to shrink drug production costs. In addition, this collaboration would also culminate in reaching out to poor countries that are not able to provide their communities and patients with cost-effective essential medicines.

  10. Health claims on food products in Southeast Asia: regulatory frameworks, barriers, and opportunities.

    Science.gov (United States)

    Tan, Karin Y M; van der Beek, Eline M; Chan, M Y; Zhao, Xuejun; Stevenson, Leo

    2015-09-01

    The Association of Southeast Asian Nations aims to act as a single market and allow free movement of goods, services, and manpower. The purpose of this article is to present an overview of the current regulatory framework for health claims in Southeast Asia and to highlight the current barriers and opportunities in the regulatory frameworks in the Association of Southeast Asian Nations. To date, 5 countries in Southeast Asia, i.e., Indonesia, Malaysia, the Philippines, Singapore, and Thailand, have regulations and guidelines to permit the use of health claims on food products. There are inconsistencies in the regulations and the types of evidence required for health claim applications in these countries. A clear understanding of the regulatory frameworks in these countries may help to increase trade in this fast-growing region and to provide direction for the food industry and the regulatory community to develop and market food products with better nutritional quality tailored to the needs of Southeast Asian consumers. © The Author(s) 2015. Published by Oxford University Press on behalf of the International Life Sciences Institute. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.

  11. Managing multiple facets of risk in new product alliances

    NARCIS (Netherlands)

    Lee, R.P.; Johnson, J.L.

    2010-01-01

    The trend of forming alliances to develop new products continues; however, many of these new product alliances fail. As such we explore how key risk types intrinsic in new product alliances, performance, relational, and knowledge appropriation risks, influence alliance success. Further, we theorize

  12. Pan-European management of electricity portfolios: Risks and opportunities of contract bundling

    International Nuclear Information System (INIS)

    Gampert, Markus; Madlener, Reinhard

    2011-01-01

    Due to the liberalization of energy markets in the European Union, today's European utilities not only focus on electricity supply, but also offer exchange-traded 'structured products' or portfolio management for unbundling financial and physical risk positions. Many utilities are only able to provide these services in their domestic markets. In a globalized economy, the need for a centrally organized pan-European portfolio management has arisen, as it allows a simplified commodity sourcing in combination with an optimized risk management. In this paper, we examine the challenges to be overcome for establishing a European-wide bundling of electricity contracts. For this purpose, a case study based on the business perspective of RWE Supply and Trading in Central and Eastern Europe is carried out. In a first step, we analyze general requirements for a pan-European bundling of electricity contracts. Then, RWE's situation in Europe is examined, based on which we finally propose a concept to meet customer demands in Central and Eastern Europe. - Research highlights: → Analysis of electricity market liberalization in Central and Eastern Europe. → Identification of requirements and problems for pan-European bundling of contracts. → Case study based on RWE Supply and Trading perspective in Central and Eastern Europe. → Model development for pan-European unbundling of financial/physical risk positions.

  13. Summaries of important areas for mineral investment and production opportunities of nonfuel minerals in Afghanistan

    Science.gov (United States)

    Peters, Stephen G.; King, Trude V.V.; Mack, Thomas J.; Chornack, Michael P.

    2011-01-01

    The U.S. Geological Survey (USGS) and the U.S. Department of Defense Task Force for Business and Stability Operations (TFBSO) entered into an agreement with the Afghanistan Geological Survey to study and assess the fuel and nonfuel mineral resources of Afghanistan from October 2009 to September 2011 so that these resources could be economically extracted to expand the economy of Afghanistan. This report summarizes the results of joint studies on 24 important areas of interest (AOIs) of nonfuel mineral resources that were identified for mineral investment and production opportunities in Afghanistan. This report is supported by digital data and archival and non-USGS reports on each AOI, and these data are available from the Afghanistan Geological Survey Data Center in Kabul (http://mom.gov.af/en/ and http://www.bgs.ac.uk/afghanminerals/) and for viewing and download on the USGS public Web site and in a separate viewer at http://mapdss2.er.usgs.gov/.

  14. Genetic opportunities to enhance sustainability of pork production in developing countries: A model for food animals

    International Nuclear Information System (INIS)

    Forsberg, C.W.; Golovan, S.P.; Ajakaiye, A.; Fan, M.Z.; Hacker, R.R.; Phillips, J.P.; Meidinger, R.G.; Kelly, J.M.

    2005-01-01

    Currently there is a shortage of food and potable water in many developing countries. Superimposed upon this critical situation, because of the increasing urban wealth in these countries, there is a strong trend of increased consumption of meat, and pork in particular. The consequence of this trend will be increased agricultural pollution, resulting not only from greater use of chemical fertilizer, but also from manure spread on land as fertilizer that may enter freshwater and marine ecosystems causing extensive eutrophication and decreased water quality. The application of transgenic technologies to improve the digestive efficiency and survival of food animals, and simultaneously decreasing their environmental impact is seen as an opportunity to enhance sustainability of animal agriculture without continued capital inputs. Transgenes expressed in pigs that have potential include, for example, genes coding for phytase, lactalbumin and lactoferrin. At the University of Guelph, Escherichia coli phytase has been expressed in the salivary glands of the pig. Selected lines of these pigs utilize plant phytate phosphorus efficiently as a source of phosphorus and excrete faecal material with more than a 60 percent reduction in phosphorus content. Because of their capacity to utilize plant phytate phosphorus and to produce less polluting manure they have a valuable trait that will contribute to enhanced sustainability of pork production in developing countries, where there is less access to either high quality phosphate supplement or phytase enzyme to include in the diet. Issues that require continued consideration as a prelude to the introduction of transgenic animals into developing countries include food and environmental safety, and consumer acceptance of meat products from genetically modified animals. (author)

  15. Constraints and opportunities for sustainable crop production in rainfed areas of pothwar plateau

    International Nuclear Information System (INIS)

    Ghafoor, A.; Shafiq, M.; Aslam, M.

    2006-01-01

    The rainfed areas, commonly known as barani tract, accounts for about 25% of the total cropped area in the Punjab. The Pothwar plateau comprising 1.82 million hectare, is the largest contiguous block of rainfed areas in Punjab. Low and erratic rainfall, water-erosion hazard, inadequate depth of soil and poor soil-fertility are the main limitations affecting the production-potential of these areas. To ensure that farmers readily adopt the agricultural technologies developed by the research-system, these should be based on real-life problems, appropriate to the natural and socio-economic environments in which farmers make decisions. The present study was undertaken in tehsils Fatehjang and Gujar Khan of Pothwar plateau, to broadly understand farmers perceptions and approaches for rainwater-harvesting and soil-fertility management. It was observed that farm size was relatively bigger in Fatehjang than Gujar Khan. About 86% and 63% of respondents in Gujar Khan and Fatehjang cultivated their own lands. Nearly 40% of respondents in both the tehsils had their lands in 3 to 6 parcels, which hindered the farm-operation and soil and water conservation activities. The uses of fertilizers are sub-optimal and imbalanced. The soil-fertility is going down. The rainwater-conservation practices are not being adopted, due to high cost of machinery and disinterest of farmers in agriculture. The farming is going to be come un- economical. The analysis of strengths, weaknesses, opportunities and threats (SWOT) was carried out and the results are discussed. Some recommendations have been proposed to control soil-erosion, moisture-stress and fertility-degradation and to sustain agricultural production in these areas. (author)

  16. DETERMINATION OF POTENTIAL OPPORTUNITIES FOR THE FOOD PROVISION WITH GRAIN PRODUCTION: A UKRAINIAN AND EUROPEAN VIEWPOINT

    Directory of Open Access Journals (Sweden)

    Valentina Mushtay

    2017-12-01

    Full Text Available The purpose of the paper is to determine the potential of the food provision of the Sumy region. The agricultural production in the region is not just a complex of the industries, developing independently from each other, but the rational and systematic combination of all elements and factors of production under certain specific natural and economic conditions, the interrelated development of various branches of agriculture, first and foremost, the rational combination of scientifically grounded systems of farming and livestock, the optimal combination of which lies in their rational interconnection. What is important to notice is that between the volumes of agricultural production and food consumption in the agro-industrial countries, there is a direct relationship with the total amount of consumption, because the manufacturers of this production and most of its consumers are the same individuals. Along with this, the main problems, which may occur in the growth of production volume in the agrifood complex of the transition economy, could be: the low purchasing power of the population and insufficient level of the development of product promotion infrastructure. Having regard to the principles of agricultural location, and in view of a range of the above problems, in our opinion, it stands to reason that the issue of the region selfprovision with the main types of production, which should be affordable to the average consumer, i.e. be solvent in effective demand, is the most pressing. It is essential to put emphasis on the fact that the theoretical and practical aspects of the formation of the regional food policy and the market strategy of their development, the motivational potential of their existence in the market economy environment require further research. The methodology of the study. When conducting this research, we used the statistical records of Sumy Region for the last 3 years and the statistical records of EU-28 for the last year

  17. A Study of Contract Broiler Production in Lombok, NTB: An Opportunity of Introducing Syariah Partnership

    Directory of Open Access Journals (Sweden)

    B. Indarsih

    2010-08-01

    Full Text Available A study to evaluate the implementation of integrated poultry production through contract farming system in Lombok, NTB was carried out from June to November 2009. The descriptive methods were used whilst the data was collected using survey methods. Fifty contract farmers were selected to measure the business performance with references on management, performance production index, FCR, and percentage of mortality. The results of this study indicated that the contract broiler production was chosen due to: (1 risk sharing (27.6%, financial credits (25.8%, and the guarantee of marketing (23.3 %. Dissatisfaction particularly in aspects of incentive determination, the quota, and margins. The margin ratios between farmers and integrators, 30%: 70%; 40%: 60% or 50%: 50% with no clear reasons. Performance parameter was as an expectation, suggesting feed quality and management aspects were well implemented. In respect to Syariah bank, its outstanding was well understood but it have not been attractive to the contract farmers. The capital is not the main reason to work with the integrators. The government involvement was needed to encourage poultry industry growth and looking for the new potential region and legislation on maintaining environment. New investors should be encouraged to overcome instability price.

  18. Knowledge Production and Distribution by Institutions of Higher Education in Sub-Saharan Africa: Opportunities and Challenges

    Science.gov (United States)

    Ondari-Okemwa, E.

    2011-01-01

    This article focuses on available opportunities and challenges which institutions of higher education in sub-Saharan Africa face in producing and distributing knowledge. Institutions of higher education are also expected to produce knowledge workers for the knowledge economy. Knowledge production falls into Mode 1, in which problems are set and…

  19. The Value-for-Money Discourse: Risks and Opportunities for R4D

    International Development Research Centre (IDRC) Digital Library (Canada)

    shanks@idrc.ca

    challenge and an opportunity for research- focused organizations ... that stifle social, economic and political ... actual results, using both qualitative and quantitative measures to ... approach to interpreting the VfM discourse by ... methodology.

  20. Opportunities for mitigating pathogen contamination during on-farm food production.

    Science.gov (United States)

    Doyle, Michael P; Erickson, Marilyn C

    2012-01-16

    Fruits, vegetables, and meat are susceptible to contamination by foodborne pathogens at many points from production through preparation in the home. This review will largely highlight approaches and progress made in the last five years to address strategies to reduce pathogen contamination in animal production but will also touch on the emerging field of preharvest produce food safety. Mitigation strategies can be divided into those that address pathogen reduction in the environment and those that target reduction/elimination of pathogen contamination in animals or plants. The former strategy has been encompassed in studies evaluating sanitation treatments of facilities as well as in numerous epidemiologic risk assessment studies (both on-farm assessments and computer simulation models) that identify management practices that impact pathogen prevalence in animals. Interventions to significantly reduce pathogen exposure via feed or water are dependent on their role as a significant contributor to pathogen contamination in the animal production system. In addition, inconsistent results obtained with interventions of dietary additives or formulation modifications (grain versus forage; inclusion of distiller's grains) on pathogen prevalence in animals have been attributed to a range of factors including target organism, grain type, level of inclusion, the animal's health or stress level, and ability to survive the gastric acidic conditions. Recent attempts to microencapsulate organic acids or bacteriophage within feed have met with only marginal improvements in reducing pathogen carriage in animals but this approach may have greater potential with other antimicrobial additives (i.e., essential oils). Bacteriophage therapy, in general, can significantly reduce pathogen carriage in animals but based on its transient nature and the potential for development of phage-resistant subpopulations, this approach should be administered to animals just prior to slaughter and

  1. Opportunities and constraints in the subsistence production and marketing of indigenous vegetables in East and Central Africa

    OpenAIRE

    Schippers, Rudy; Fereday, Nicholas

    1998-01-01

    This report summarises the results of market and production surveys carried out in both the dry and wet seasons in Cameroon and Uganda during 1997/98 as part of the DFID fimded project "Opportunities and constraints in the subsistence production and marketing of indigenous vegetables in East and Central Africa (A0699)". The main objective of the study was to establish the socio-economic significance of indigenous vegetables compared to exotic ones. This project is a follow up to the strategy ...

  2. Companies and Climate Risk: Opportunities to Engage the Business Community in Promoting Climate-conscious Policies (Invited)

    Science.gov (United States)

    Goldman, G. T.; Rogerson, P.

    2013-12-01

    Regardless of their policy orientation, the business community has an interest in how climate change impacts will affect their operations and ultimately change their bottom line. The reality that climate change presents material and financial risks to many companies in diverse sectors of the economy presents an opportunity to engage companies on climate-related issues. Company investors are exposed to such financial risks and can pressure public companies to change behavior through shareholder resolutions, voting, and election of new board members. The US Securities and Exchange Commission (SEC) obligates all publicly traded companies to discuss risks that might materially affect their business in their annual Form 10-K filings. In 2010, the guidance for the Form 10-K specifically suggested that companies consider and discuss any significant risks to their business from climate change--both from its physical effects and from impacts of climate regulations. Form 10-Ks for 28 US companies were analyzed for the years 2009 and 2010. Results indicate that some companies comprehensively considered climate-related risks. However, in spite of the SEC guidance, some fail to mention climate change at all. Additionally, many companies discuss only the impacts that regulation would have on their business--not the physical effects of climate change itself. The lack of consideration of climate-related risks in companies' risk assessments demonstrates a need for a more uniform understanding of SEC requirements and additionally, this state of affairs presents an opportunity to push companies to more deeply consider climate change impacts. Several avenues are available for engaging with companies themselves, their shareholders, the SEC, and the public. We will explore what strategies have been effective for engaging such actors and what further opportunities exist for working with the business community to promote more climate-conscious policies and practices.

  3. Whither Risk Assessment: New Challenges and Opportunities a Third of a Century After the Red Book.

    Science.gov (United States)

    Greenberg, Michael; Goldstein, Bernard D; Anderson, Elizabeth; Dourson, Michael; Landis, Wayne; North, D Warner

    2015-11-01

    Six multi-decade-long members of SRA reflect on the 1983 Red Book in order to examine the evolving relationship between risk assessment and risk management; the diffusion of risk assessment practice to risk areas such as homeland security and transportation; the quality of chemical risk databases; challenges from other groups to elements at the core of risk assessment practice; and our collective efforts to communicate risk assessment to a diverse set of critical groups that do not understand risk, risk assessment, or many other risk-related issues. The authors reflect on the 10 recommendations in the Red Book and present several pressing challenges for risk assessment practitioners. © 2015 Society for Risk Analysis.

  4. The identification of aluminium-resistance genes provides opportunities for enhancing crop production on acid soils.

    Science.gov (United States)

    Ryan, P R; Tyerman, S D; Sasaki, T; Furuichi, T; Yamamoto, Y; Zhang, W H; Delhaize, E

    2011-01-01

    Acid soils restrict plant production around the world. One of the major limitations to plant growth on acid soils is the prevalence of soluble aluminium (Al(3+)) ions which can inhibit root growth at micromolar concentrations. Species that show a natural resistance to Al(3+) toxicity perform better on acid soils. Our understanding of the physiology of Al(3+) resistance in important crop plants has increased greatly over the past 20 years, largely due to the application of genetics and molecular biology. Fourteen genes from seven different species are known to contribute to Al(3+) tolerance and resistance and several additional candidates have been identified. Some of these genes account for genotypic variation within species and others do not. One mechanism of resistance which has now been identified in a range of species relies on the efflux of organic anions such as malate and citrate from roots. The genes controlling this trait are members of the ALMT and MATE families which encode membrane proteins that facilitate organic anion efflux across the plasma membrane. Identification of these and other resistance genes provides opportunities for enhancing the Al(3+) resistance of plants by marker-assisted breeding and through biotechnology. Most attempts to enhance Al(3+) resistance in plants with genetic engineering have targeted genes that are induced by Al(3+) stress or that are likely to increase organic anion efflux. In the latter case, studies have either enhanced organic anion synthesis or increased organic anion transport across the plasma membrane. Recent developments in this area are summarized and the structure-function of the TaALMT1 protein from wheat is discussed.

  5. effectiveness of technological options for minimising production risks

    African Journals Online (AJOL)

    ACSS

    preferred technologies in reducing production risk related to climate variability in Eastern Uganda. Data for this study were ..... Set of technological options employed by farmers to reduce climate-induced production risk. Dummy = 1 if farmer. 0.71. 0.46 ..... cation exchange capacity for holding nutrients against leaching loss.

  6. Farm Technologies and Production Risk in the Face of Climate ...

    African Journals Online (AJOL)

    In countries where insurance and credit markets are thin or missing, production and consumption risks play a critical role in the choice and use of production inputs and adoption of new farm technologies. This paper investigated the effect of selected farm technologies and their risk implications in different rainfall patterns of ...

  7. Do youth mentoring programs change the perspectives and improve the life opportunities of at-risk youth?

    OpenAIRE

    Rodríguez-Planas, Núria

    2014-01-01

    Mentoring programs such as Big Brothers Big Sisters of America have been providing positive role models and building social skills for more than a century. However, most formal mentoring programs are relatively novel and researchers have only recently begun to rigorously evaluate their impact on changing at-risk youth’s perspectives and providing opportunities for them to achieve better life outcomes. While a variety of mentoring and counseling programs have emerged around the world in recent...

  8. Market potential and opportunities for commercialization of traditional meat products in North East Hill Region of India.

    Science.gov (United States)

    Kadirvel, G; Banerjee, Bandita B; Meitei, Surajit; Doley, S; Sen, Arnab; Muthukumar, M

    2018-02-01

    The North Eastern (NE) India is renowned for its preference for animal-based food. This region is known for its traditional meat products. However, the popularity of these products remains confined to the specific community/location. The knowledge on the traditional preparation methods is generally passed across generations through practice and word of mouth. The traditional style of preparation and the specific ingredients added to each product makes them unique. In this review, an attempt has been made to identify the initiatives, opportunities, and market potential for commercialization of the traditional meat products. These unique features and properties of the traditional meat products have been highlighted. The commercialization of these products will enhance entrepreneurship development and ensure quality ethnic products to the consumer in the NE hill region of India.

  9. Market potential and opportunities for commercialization of traditional meat products in North East Hill Region of India

    Science.gov (United States)

    Kadirvel, G.; Banerjee, Bandita B.; Meitei, Surajit; Doley, S.; Sen, Arnab; Muthukumar, M.

    2018-01-01

    The North Eastern (NE) India is renowned for its preference for animal-based food. This region is known for its traditional meat products. However, the popularity of these products remains confined to the specific community/location. The knowledge on the traditional preparation methods is generally passed across generations through practice and word of mouth. The traditional style of preparation and the specific ingredients added to each product makes them unique. In this review, an attempt has been made to identify the initiatives, opportunities, and market potential for commercialization of the traditional meat products. These unique features and properties of the traditional meat products have been highlighted. The commercialization of these products will enhance entrepreneurship development and ensure quality ethnic products to the consumer in the NE hill region of India. PMID:29657390

  10. Agricultural Education: Key to Providing Broader Opportunities for Third World Women in Production Agriculture.

    Science.gov (United States)

    Lelle, Mark A.; Holt, Barbara A.

    1987-01-01

    The authors focus on providing opportunities for women in Third World countries in agriculture. A review of the body of knowledge in agricultural development and of the issues surrounding current world food crises is included. (CH)

  11. The possibility of drought risk reduction in corn production

    Directory of Open Access Journals (Sweden)

    Pajić Nemanja

    2016-01-01

    Full Text Available Weather derivatives are contemporary instruments for insurance risk of drought in agricultural production. Corn production is particularly sensitive to this risk, and the amount of the yield of this crop is in significant correlation with the July-August rainfall amount. Oscillations of production output, caused by the risk of drought, are reflected directly on the fluctuations of the financial result. The application of weather derivatives may decrease the variability of the mentioned economic parameter in corn production. In the investigated example of corn production, simulating the application of the weather option the coefficient of variation of realized financial results decreased by 9.64% compared to the version without the insured risk. At the same time, using the analysed insurance instrument, the risk of achieving a negative financial result is eliminated.

  12. Biogeoscience opportunities to address agricultural supply chain risk: observations, methods, and applications

    Science.gov (United States)

    Wolf, A.; Gaitan, C. F.; Thomas, T.; Watts, D.; Bollinger, J.

    2017-12-01

    Food and agriculture is the largest global industry, at $7.8Tn annual value, and is also the least digitized industry. As a consequence, the inefficiencies in this industry are staggering: yield gaps below potential are 20-70% worldwide, and of the crops that are produced, 20-50% are lost from the time of harvest up to consumption. Where some frame the challenges in agriculture as "grow more with less," a more useful analysis is around risk and uncertainty. In emerging markets, lack of geospatial data makes it difficult to recommend improved seeds or fertilizers for particular locales, therefore risky to make operating loans, impossible to accurately price crop insurance, and ultimately poses challenges in making contracts for delivery to processors that bring ag products into the food system. In developed markets, the ever increasing demands around immediacy, transparency, quality, crop novelty and food safety are straining the capacity of growers and processors to keep up. We have come to see this as a challenge in developing predictions joining both buyers and sellers around a shared set of facts on harvest timing, total yield, and post harvest quality. While these challenges have been met historically from government agencies and marketing boards reporting seasonal and regional forecasts, in many instances these are insufficient for making critical operational decisions on short timescales. In this talk, we will present a new set of measurements and analytical tools that enable unprecedented granularity in predictions to reduce risk and uncertainty in the food and ag supply chain, with special attention to applications that have potential to be economically self-sustaining.

  13. Coal supply and transportation markets during Phase One: Change, risk and opportunity. Final report

    International Nuclear Information System (INIS)

    Heller, J.N.; Kaplan, S.

    1996-01-01

    The Clean Air Act Amendments of 1990 (CAAA) required many utilities to sharply reduce sulfur emissions by January 1, 1995. This study describes and analyzes how the coal and transportation markets responded to this major development. The study focuses on five key coal supply regions and their associated transportation networks: the Uinta Basin (Colorado/Utah), Wyoming Powder River Basin, Illinois Basin, Monongahela region (Pittsburgh seam) and the central Appalachian region. From these regional studies, the report identifies key risk areas for future coal planning and general lessons for the fuels planning process. The study provides statistical information on coal production, demand, and transportation flows for each region. The analysis for each region focuses on developments which were generally unexpected; e.g., the relatively large volumes of medium-sulfur coal produced in the Illinois Basin and Monongahela region, the eastern penetration of Utah and Colorado coals, and the relatively modest growth in demand for central Appalachian coals. These developments generally worked to the advantage of utilities; i.e., medium- and low-sulfur coal was available at a lower price, in greater volumes and from a wider range of sources than many had expected. Utilities both took advantage of and helped to encourage these developments in the coal and transportation market. Looking ahead to Phase 11 strategies and future coal procurement, a major challenge will be to maintain the choice among supply and transportation alternatives which was so important to utility success in Phase 1. The report identifies rail transportation to be the major area of risk in most regions

  14. Risk and Uncertainty in Production Economics | Otaha | African ...

    African Journals Online (AJOL)

    One of the most celebrated and feared concepts in the World today are risk which is the product of uncertainty. Risk and uncertainty are often used interchangeably by many economists as if they are the same thing, but it is not true. While risk can be measured and estimated, and even ensured, uncertainty can not.

  15. Ultra high risk of psychosis on committal to a young offender prison: an unrecognised opportunity for early intervention.

    LENUS (Irish Health Repository)

    Flynn, Darran

    2012-08-01

    The ultra high risk state for psychosis has not been studied in young offender populations. Prison populations have higher rates of psychiatric morbidity and substance use disorders. Due to the age profile of young offenders one would expect to find a high prevalence of individuals with pre-psychotic or ultra-high risk mental states for psychosis (UHR). Accordingly young offender institutions offer an opportunity for early interventions which could result in improved long term mental health, social and legal outcomes. In the course of establishing a mental health in-reach service into Ireland\\'s only young offender prison, we sought to estimate unmet mental health needs.

  16. MANAGING RISK BY COORDINATING INVESTMENT, MARKETING, AND PRODUCTION STRATEGIES

    OpenAIRE

    Johnson, Donald A.; Boehlje, Michael

    1983-01-01

    This study of the farm firm integrates long run investment and financial decisions, and short-run production and marketing decisions into a single decision framework that includes both time and risk. The results suggest that the use of various strategies for managing market risks allow the entrepreneur to accept mores risk in investing and producing; and that an integrated analysis of production, marketing and investment-financing alternatives is essential to make accurate recommendations abo...

  17. Stakeholder consultations and opportunities for integrating socio-behavioural factors into the pesticide risk analysis process.

    Science.gov (United States)

    Calliera, Maura; Marchis, Alex; Sacchettini, Gabriele; Capri, Ettore

    2016-02-01

    The pesticide risk analysis process is well regulated in the EU, especially in relation to placing on the market authorisation procedures, but in order to avoid risks for human health and environment in the use phase, information on how these substances are employed and on socio-behavioural factors that can influence the exposure have to be taken into account. To better explore reasons about the gap between risk assessment and risk management, within the EU FP7 Health and Environmental Risks: Organisation, Integration and Cross-fertilisation of Scientific Knowledge (HEROIC) project, a stepwise stakeholder's consultation process was developed using a mixed approach in two different phases (survey and roundtable). We elicited stakeholder views regarding factors that could limit the pesticide risk assessment phase linked on how the knowledge is produced and the way the data are used in risk management and in risk communication, also taking into account qualitative factors such as responsibility, trust and behaviours, which could have impact on risk assessment policies. Activities deployed indicate that some changes and interaction are needed to better define the problems at the formulation stage, and the type of information risk assessor has to provide, to better inform risk manager in addressing different societal needs, to strengthen the credibility of the process of risk assessment and improve the effectiveness of policies. Integrations between disciplines may initially increase the complexity but in turn will provide a better and more useful estimation of the risk, reinforce transparency and drive a more efficient use of risk management resources.

  18. Risk assessment of topically applied products

    DEFF Research Database (Denmark)

    Søborg, Tue; Basse, Line Hollesen; Halling-Sørensen, Bent

    2007-01-01

    The human risk of harmful substances in semisolid topical dosage forms applied topically to normal skin and broken skin, respectively, was assessed. Bisphenol A diglycidyl ether (BADGE) and three derivatives of BADGE previously quantified in aqueous cream and the UV filters 3-BC and 4-MBC were used...... as model compounds. Tolerable daily intake (TDI) values have been established for BADGE and derivatives. Endocrine disruption was chosen as endpoint for 3-BC and 4-MBC. Skin permeation of the model compounds was investigated in vitro using pig skin membranes. Tape stripping was applied to simulate broken...... parameters for estimating the risk. The immediate human risk of BADGE and derivatives in topical dosage forms was found to be low. However, local treatment of broken skin may lead to higher exposure of BADGE and derivatives compared to application to normal skin. 3-BC permeated skin at higher flux than 4-MBC...

  19. The risks of inclusion: shifts in governance processes and upgrading opportunities for cocoa farmers in Ghana

    NARCIS (Netherlands)

    Laven, A.C.

    2010-01-01

    This PhD study provides a detailed description and analysis of upgrading opportunities for small-scale cocoa farmers in Ghana. It shows how and why producers do, or do not, benefit from being inserted in a global value chain that is increasingly driven by multinational cocoa processors and chocolate

  20. Opportunities for Local for Local Food Production. A Case in the Dutch Fruit and Vegetables

    NARCIS (Netherlands)

    Visser, J.; Trienekens, J.H.; Beek, van P.

    2013-01-01

    This paper investigates the opportunities for farmers to produce for local consumers, based on a case study in the Dutch horticulture sector. Main requirements for the set-up of a local chain of supply chain actors are investigated. Producer requirements are added value, availability of time,

  1. Proceedings of the Canadian Institute's 4. annual oil sands supply and infrastructure conference : maximizing opportunity and mitigating risks in a rapidly growing market

    International Nuclear Information System (INIS)

    2006-01-01

    This conference addressed the challenges facing oil sands development, with particular reference to supply and infrastructure issues. Updates on oil sands markets and opportunities were presented along with strategies for mitigating risks in a rapidly growing market. The best practices for supplying a demanding market through supply shortages and high prices were identified along with policies that should be implemented to help overcome labour shortages. Some presentations expressed how commodities pricing and trends can impact business. Others showed how markets in China and the United States are prepared for oilsands products. The views of other international companies on oil sands was also discussed along with proposed plans to eliminate the infrastructure congestion and risks caused by expanding oil sands development. The challenges and benefits of investing in Alberta's oil sands were reviewed along with strategies to enhance upgrading and refining capacity in the province. Economic drivers and the creation of new markets were examined, and various export opportunities were reviewed along with industry management challenges concerning human resources, labour supply, training and education. The conference featured 10 presentations, of which 3 have been catalogued separately for inclusion in this database. refs., tabs., figs

  2. Sharing risk and reward - floating production contractorship

    International Nuclear Information System (INIS)

    Gisvold, K.M.

    1994-01-01

    The conference paper summarizes the contractual experience so far gained on Petrojarl 1 floating production system and the associated shuttling services on the Norwegian continental shelf. The paper attempts to draw some lines into the future with respect to development of the business format and the evolution of the relationship between the contractor and the various oil companies in question. Turnkey production services as well as transport and project services to the oil industry are provided. The scope of these services ranges from top of the sea bed wellhead to quayside at the refinery, and is based on ownership control of the employed vessels as well as complete manning of all services. 7 figs

  3. Risk Management for New Product Development Projects in Food Industry

    Directory of Open Access Journals (Sweden)

    Porananond, D.

    2014-07-01

    Full Text Available Project risk management provides a guideline for decision making in new product development (NPD projects, reducing uncertainty and increasing success rate. However, the acceptance of formal risk management applications in industry, especially for NPD projects is still in question. A study of a food conglomerate in Thailand found that only 9% of NPD projects used a systematic approach for managing risk. 61% of the projects realised the importance of risk management, while the remaining 30% did not involve risk management at all. This study aims to develop a risk management model for NPD projects in the food industry. The first section of this paper reviews the literature on risk management theory, including international standards for risk and project management (ISO31000 and ISO21500, publications for the Project Management Body of Knowledge (PMBOK, by a professional organisation the Project Management Institute (PMI, and also academic research. 182 academic papers, published between January 2002 and August 2012 were selected. The second part interviews conducted with eight NPD experts from five of the major food manufacturers in Thailand to examine their risk management practices and problems. Conclusions are made on five topics : classification of research method, project type and industrial segment, distribution of articles by region, tools & techniques for risk management and risk factors in projects. Specific requirements of risk management for NPD projects in the food industry are identified. A risk management model and the concept of risk management applications for the food industry are proposed.

  4. Atomic risk insurance. Risk policy, safety production and expertise in Germany and the USA 1945 - 1986

    International Nuclear Information System (INIS)

    Wehner, Christoph

    2017-01-01

    The book covers the following chapters: (I) Between threat and promise: Political change and the corporate perception, the burden of the atomic bomb, promise of nuclear energy risk criticism in the pre-ecological phase, nuclear risk as investment restraint; (II) Risk policy at the insurability limit: hazard knowledge, safety production and insurance expertise in the German nuclear policy (1955-1962); (III) Risk policy beyond the catastrophe, insurability interpretation, concepts and conflicts (1957-1968); (IV) Scandalization of risk policy: safety production, confidence and expertise in the nuclear controversial debate (1969 - 1979); (V) Nuclear risk policy and the challenge of the ''risk society'' (1975-1986); (VI) From safety production to hazard probe: atomic energy And the change of insurance.

  5. Opportunity of integrated production of "Ceratophyllum demersum" in a nutrition trial with "Carassius auratus"

    OpenAIRE

    Santana García, Gustavo Julián

    2016-01-01

    [EN]The integrated culture of fish and plant in a recirculated system is called aquaponics, where a mutual benefit have been demonstrated for the cocultured species. Today this practice is still not well known for the most studied consumed freshwater species, and almost nothing has been done for aquarium species. The objective of present work was to study the opportunity of growing one of the most selled aquarium plant coontail (Ceratophyllum demersum) in a coculture with the goldfish (Carass...

  6. Risk identification and evaluation of customer collaboration in product development

    Directory of Open Access Journals (Sweden)

    Xuefeng Zhang

    2015-05-01

    Full Text Available Purpose: The purpose of this paper is to identify risk factors that caused by customer collaboration in new product development systematically, and propose an approach to judge which risk factors are critical and catch substantial attention. Design/methodology/approach: This study identifies risk factors according to the results of case studies of enterprises in china. On this basis, an improved rough number approach is put forward to evaluate the importance of risk factors. Findings: Firstly, classify risk factors into three aspects. Then, present a risk factor set, which include thirty-seven risk factors. At last, determine which risk factors are critical by using an improved rough number approach. Originality/value: Considering there are few researches studying comprehensive risk factors of customer collaboration and assessing them, this paper explores a risk factor set of customer collaboration in product development stage, and proposes a novel approach, which can help to solve the problem of subjective, vague and lack of prior information of evaluation, to evaluate risk factors.

  7. Profit and Risk Measures in Oil Production Optimization

    DEFF Research Database (Denmark)

    Capolei, Andrea; Foss, Bjarne; Jørgensen, John Bagterp

    2015-01-01

    In oil production optimization, we usually aim to maximize a deterministic scalar performance index such as the profit over the expected reservoir lifespan. However, when uncertainty in the parameters is considered, the profit results in a random variable that can assume a range of values dependi...... pro and cons for each of them. Finally, among the presented risk measures, we identify two of them as appropriate risk measures when minimizing the risk....

  8. Analysis of the proposed EU regulation concerning biocide products and its opportunities for alternative approaches and a toxicology for the 21st century (t4 report).

    Science.gov (United States)

    Ferrario, Daniele; Rabbit, Richard R

    2012-01-01

    On June 12, 2009, the European Commission adopted a proposal for a Regulation concerning the placement on the market and use of biocidal products, which, when it enters into force on January 1, 2013, will repeal and replace Directive 98/8/EC. The main reason for the revision of the current Directive was to promote best practices for environmental and human health protection, along with implementation of current developments in safety testing in order to create safer biocides. Moreover, the proposed Regulation aims to take into consideration the newest legislation on chemicals. This article evaluates the proposed Regulation in comparison to Directive 98/8/EC. Although the new proposal requires the sharing of vertebrate animal test data, both for product authorization and for newly developed active substances, it misses - in contrast to REACH - the opportunity to recognize the accelerating development of alternative approaches to animal testing, most recently with new momentum provided by "Toxicity Testing for the 21st Century", and to support the evolution of toxicology towards a new approach to testing. The new methods promise not only to decrease animal pain and suffering, but also to provide faster results and better prediction for human risk assessment compared to traditional methods. Unfortunately, methods mandated for human risk assessment in the proposal are still mainly based on traditional animal study extrapolation. We put forward and discuss possible alternative strategies, such as in vitro testing, integrated testing strategies, toxicokinetics, "omics", systems biology, bioinformatics, and computational modeling, all of which could be more encouraged by the proposal. Current opportunities to improve our tools for biocide risk assessment are discussed, delineating advantages, limitations, and development needs. It is suggested to open the proposed Regulation to alternative approaches that are based on human biology more than on extrapolation from animals

  9. Proliferation Risks of Fusion Energy: Clandestine Production, Covert Production, and Breakout

    International Nuclear Information System (INIS)

    Goldston, R.J.; Glaser, A.; Ross, A.F.

    2009-01-01

    Nuclear proliferation risks from fusion associated with access to weapon-usable material can be divided into three main categories: (1) clandestine production of fissile material in an undeclared facility, (2) covert production of such material in a declared and safeguarded facility, and (3) use of a declared facility in a breakout scenario, in which a state begins production of fissile material without concealing the effort. In this paper we address each of these categories of risk from fusion. For each case, we find that the proliferation risk from fusion systems can be much lower than the equivalent risk from fission systems, if commercial fusion systems are designed to accommodate appropriate safeguards

  10. Collaborative Strategies for Sustainable EU Flood Risk Management: FOSS and Geospatial Tools—Challenges and Opportunities for Operative Risk Analysis

    Directory of Open Access Journals (Sweden)

    Raffaele Albano

    2015-12-01

    Full Text Available An analysis of global statistics shows a substantial increase in flood damage over the past few decades. Moreover, it is expected that flood risk will continue to rise due to the combined effect of increasing numbers of people and economic assets in risk-prone areas and the effects of climate change. In order to mitigate the impact of natural hazards on European economies and societies, improved risk assessment, and management needs to be pursued. With the recent transition to a more risk-based approach in European flood management policy, flood analysis models have become an important part of flood risk management (FRM. In this context, free and open-source (FOSS geospatial models provide better and more complete information to stakeholders regarding their compliance with the Flood Directive (2007/60/EC for effective and collaborative FRM. A geospatial model is an essential tool to address the European challenge for comprehensive and sustainable FRM because it allows for the use of integrated social and economic quantitative risk outcomes in a spatio-temporal domain. Moreover, a FOSS model can support governance processes using an interactive, transparent and collaborative approach, providing a meaningful experience that both promotes learning and generates knowledge through a process of guided discovery regarding flood risk management. This article aims to organize the available knowledge and characteristics of the methods available to give operational recommendations and principles that can support authorities, local entities, and the stakeholders involved in decision-making with regard to flood risk management in their compliance with the Floods Directive (2007/60/EC.

  11. Non-timber forest products in Central Appalachia: market opportunities for rural development (poster abstract)

    Science.gov (United States)

    A.L. Hammett; J.L. Chamberlain

    1999-01-01

    The gathering of forest products has supplemented the incomes of Central Appalachia residents for many generations. Non-timber forest products (NTFPs) can be grouped within four general categories: edibles such as mushrooms; medicinal and dietary supplements, including ginseng, gingko, and St. John?s wort; floral products such as moss, grape vines, and ferns; and...

  12. Opportunities for multivariate analysis of open spatial datasets to characterize urban flooding risks

    NARCIS (Netherlands)

    Gaitan Sabogal, S.; ten Veldhuis, J.A.E.; Rogger, M; Aksoy, H; Kooy, M

    2015-01-01

    Cities worldwide are challenged by increasing urban flood risks. Precise and realistic measures are required to reduce flooding impacts. However, currently implemented sewer and topographic models do not provide realistic predictions of local flooding occurrence during heavy rain events. Assessing

  13. Climate Change Risk Management Consulting: The opportunity for an independent business practice

    Science.gov (United States)

    Ciccozzi, R.

    2009-04-01

    The Paper outlines the main questions to be addressed with reference to the actual demand of climate change risk management consulting, in the financial services. Moreover, the Project shall also try to investigate if the Catastrophe Modelling Industry can start and manage a business practice specialised on climate change risk exposures. In this context, the Paper aims at testing the possibility to build a sound business case, based upon typical MBA course analysis tools, such as PEST(LE), SWOT, etc. Specific references to the tools to be used and to other contribution from academic literature and general documentation are also discussed in the body of the Paper and listed at the end. The analysis shall also focus on the core competencies required for an independent climate change risk management consulting business practice, with the purpose to outline a valid definition of how to achieve competitive advantage in climate change risk management consulting.

  14. 78 FR 67141 - Antimony Trioxide (ATO) TSCA Chemical Risk Assessment; Notice of Public Meetings and Opportunity...

    Science.gov (United States)

    2013-11-08

    ...On September 27, 2013, EPA announced that it would be holding three peer review meetings by web connect and teleconference on October 16, 2013, October 31, 2013, and November 14, 2013, regarding EPA's draft Toxic Substances Control Act (TSCA) chemical risk assessment, ``TSCA Workplan Chemical Risk Assessment for ATO.'' Due to the government shutdown, however, EPA has rescheduled the peer review meetings and is announcing the rescheduled meetings in this notice. EPA is also extending the due date for public comments.

  15. Applying lean thinking to risk management in product development

    DEFF Research Database (Denmark)

    Willumsen, Pelle Lundquist; Oehmen, Josef; Rossi, Monica

    2017-01-01

    This paper re-conceptualizes risk management (RM) in product development (PD) through a lean thinking perspective. Arguably, risk management in PD projects became a victim of its own success. It is often implemented as a highly formalized, compliance driven activity, ending up disconnected from...... delay or cost overrun. This paper explores the relationship between product development and risk management and proposes to make RM an integrated value adding part of PD. Through a literature review we identify the potential of re-conceptualizing RM through lean thinking. We then conceptualize...

  16. One-step production of biocommodities from lignocellulosic biomass by recombinant cellulolytic bacillus subtilis: opportunities and challenges

    Energy Technology Data Exchange (ETDEWEB)

    Zhang, Xiao-Zhou [Department of Biological Systems Engineering, Virginia Polytechnic Institute and State University, Blacksburg, VA (United States); Zhang, Yi-Heng P. [Department of Biological Systems Engineering, Virginia Polytechnic Institute and State University, Blacksburg, VA (United States); Institute for Critical Technology and Applied Science, Virginia Polytechnic Institute and State University, Blacksburg, VA (United States); BioEnergy Science Center of Department of Energy, Oak Ridge, TN (United States)

    2010-10-15

    One-step consolidated bioprocessing that integrates cellulase production, cellulose hydrolysis, and product fermentation into a single step for decreasing costly cellulase use, increasing volumetric productivity, and reducing capital investment is widely accepted for low-cost production of biofuels or other value-added biochemicals. Considering the narrow margins between biomass and low-value biocommodities, good physiological performance of industrial microbes is crucial for economically viable production. Bacillus subtilis, the best-characterized Gram-positive microorganism, is a major industrial microorganism with numerous valuable features such as hexose and pentose utilization, low-nutrient needs, fast growth rate, high protein secretion capacity, industrial safety, etc. As compared with other potential consolidated bioprocessing microorganisms such as Clostridium spp., Escherichia coli, and the yeast Saccharomyces cerevisiae, recombinant cellulolytic B. subtilis strains would be a potential platform for biocommodity production from nonfood biomass. Here, we review the advances in recombinant cellulolytic B. subtilis development and metabolic engineering for biocommodity production, and discuss the opportunities and challenges of cellulolytic B. subtilis for biocommodity production. (Copyright copyright 2010 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim)

  17. Reassessment of inclusion body-based production as a versatile opportunity for difficult-to-express recombinant proteins.

    Science.gov (United States)

    Hoffmann, Daniel; Ebrahimi, Mehrdad; Gerlach, Doreen; Salzig, Denise; Czermak, Peter

    2017-11-10

    The production of recombinant proteins in the microbial host Escherichia coli often results in the formation of cytoplasmic protein inclusion bodies (IBs). Proteins forming IBs are often branded as difficult-to-express, neglecting that IBs can be an opportunity for their production. IBs are resistant to proteolytic degradation and contain up to 90% pure recombinant protein, which does not interfere with the host metabolism. This is especially advantageous for host-toxic proteins like antimicrobial peptides (AMPs). IBs can be easily isolated by cell disruption followed by filtration and/or centrifugation, but conventional techniques for the recovery of soluble proteins from IBs are laborious. New approaches therefore simplify protein recovery by optimizing the production process conditions, and often include mild resolubilization methods that either increase the yield after refolding or avoid the necessity of refolding all together. For the AMP production, the IB-based approach is ideal, because these peptides often have simple structures and are easy to refold. The intentional IB production of almost every protein can be achieved by fusing recombinant proteins to pull-down tags. This review discusses the techniques available for IB-based protein production before considering technical approaches for the isolation of IBs from E. coli lysates followed by efficient protein resolubilization which ideally omits further refolding. The techniques are evaluated in terms of their suitability for the process-scale production and downstream processing of recombinant proteins and are discussed for AMP production as an example.

  18. Use of product databases for risk assessment purposes

    International Nuclear Information System (INIS)

    Heinemeyer, Gerhard; Hahn, Axel

    2005-01-01

    Product information databases are important prerequisites for providing data to poison centers (PC) to give adequate advice in cases of poisonings and for preparation of statistics as annual reports. For risk assessment measures, they can help for exposure assessments and for priority setting. A product database is a set of information of product and substance names, compositions, and uses of products. Data are provided due to national regulations as well as to national and international agreements between industry, international associations, e.g. the European Association of Poison Centres and Clinical Toxicologists (EAPCCT), and clinical toxicology institutions. They have different contents, i.e. complete formulations, frame formulations, and material safety data sheets. For definite identification of products, the product name should be readily taken from the labels and must be similar to the names provided by electronic media as databases. Products should be classified according to their use. The first system that has been prepared for that purpose is the ATC classification for pharmaceuticals. For chemicals, several systems e.g. the WHO-IPCS classification code, exist; the EU technical guidance document for risk assessment of chemicals is mentioning use categories, and they are used on national levels as well. For risk assessment purposes, statistics of poisonings and other health hazards are important as well as information about exposure. Linking cases of poisonings with product data enables risk assessors to perform statistical evaluations about health effects due to product use categories which can be compared to product compositions. If products are categorized by their use, information about use characteristics, such as frequencies and durations, can be derived. Hence, product categories can be taken to characterize scenarios and thus help for model estimations of exposure and respective doses

  19. Predicting PTSD using the New York Risk Score with genotype data: potential clinical and research opportunities

    Directory of Open Access Journals (Sweden)

    Boscarino JA

    2013-04-01

    Full Text Available Joseph A Boscarino,1,2 H Lester Kirchner,3,4 Stuart N Hoffman,5 Porat M Erlich1,4 1Center for Health Research, Geisinger Clinic, Danville, 2Department of Psychiatry, Temple University School of Medicine, Philadelphia, 3Division of Medicine, Geisinger Clinic, Danville, 4Department of Medicine, Temple University School of Medicine, Philadelphia, 5Department of Neurology, Geisinger Clinic, Danville, PA, USA Background: We previously developed a post-traumatic stress disorder (PTSD screening instrument, ie, the New York PTSD Risk Score (NYPRS, that was effective in predicting PTSD. In the present study, we assessed a version of this risk score that also included genetic information. Methods: Utilizing diagnostic testing methods, we hierarchically examined different prediction variables identified in previous NYPRS research, including genetic risk-allele information, to assess lifetime and current PTSD status among a population of trauma-exposed adults. Results: We found that, in predicting lifetime PTSD, the area under the receiver operating characteristic curve (AUC for the Primary Care PTSD Screen alone was 0.865. When we added psychosocial predictors from the original NYPRS to the model, including depression, sleep disturbance, and a measure of health care access, the AUC increased to 0.902, which was a significant improvement (P = 0.0021. When genetic information was added in the form of a count of PTSD risk alleles located within FKBP, COMT, CHRNA5, and CRHR1 genetic loci (coded 0–6, the AUC increased to 0.920, which was also a significant improvement (P = 0.0178. The results for current PTSD were similar. In the final model for current PTSD with the psychosocial risk factors included, genotype resulted in a prediction weight of 17 for each risk allele present, indicating that a person with six risk alleles or more would receive a PTSD risk score of 17 × 6 = 102, the highest risk score for any of the predictors studied. Conclusion: Genetic

  20. Towards a Lean Product Service Systems (PSS) Design: State of the Art, Opportunities and Challenges

    OpenAIRE

    Sassanelli, Claudio; Pezzotta, Giuditta; Rossi, Monica; Terzi, Sergio; Cavalieri, Sergio

    2015-01-01

    As for conventional products, the profit generation and the market success of Product Service Systems (PSS) critically depend on the decisions taken during the initial lifecycle stages, when PSSs are conceptualized, designed, developed and engineered. Successful cases show the adoption of lean techniques in the early stages of products development, impelling the authors to assess the application of the same approaches also to PSS development. For this reasons the paper aims to report the stat...

  1. Thinking Afresh About Processing: An Exploration of New Market Opportunities for Apple Products

    OpenAIRE

    Rowles, Kristin; Henehan, Brian M.; White, Gerald B.

    2001-01-01

    This report compiles the results of several studies focused on the markets for processed apple products. These studies were conducted as part of a multidisciplinary project examining the processing apple industry in the Northeastern United States. The purpose of the studies was to explore the potential for new products and new marketing strategies that might bring innovation to the apple industry. In the global and highly competitive markets in which apple products fight for shelf space and c...

  2. Promotion of animal products as opportunity for further development of breeding

    OpenAIRE

    Migdał W.; Živković B.; Migdał Ł.

    2011-01-01

    In order to ensure safety of meat and meat products as well as necessary repeatability of products quality throughout the food chain, raw materials producers are required to ensure appropriate condition for production (both crops and breeding). It obligates to implementation and application systems such as: Good Agriculture Practise (GAP), Good Manufacturing Practice (GMP), Good Higiene Practice (GHP), and for intermediary companies participating in raw mat...

  3. 78 FR 34313 - Funding Opportunity Title: Risk Management Education Partnerships Program

    Science.gov (United States)

    2013-06-07

    ... accordance with USDA procedures or recognized good farming practices applicable specific crop and regions... College Students who are preparing careers in agriculture; Record Keeping practices; Farm Benchmarking for production and financial management; Commodity Contracting and Hedging methods; Marketing Strategies to...

  4. Use of sanitizing products: safety practices and risk situations

    Directory of Open Access Journals (Sweden)

    Ana Aurélia Rocha da Silva

    2014-04-01

    Full Text Available OBJECTIVES: to evaluate the handling and risk factors for poisoning and/or digestive tract injuries associated with the use of sanitizing products at home. METHODS: interviews were conducted in 419 households from different regions, collecting epidemiological data from residents and risk habits related to the use and storage of cleaning products. RESULTS: sanitizing products considered to be a health risk were found in 98% of the households where the research was conducted, and in 54% of cases, they were stored in places easily accessible to children. Lye was found in 19%, followed by illicit products in 39% of homes. In 13% of households, people produced soap, and in 12% they stored products in non-original containers. The use of illicit products and the manufacture of handmade soap were associated with lower educational level of the household owners and with the regions and socioeconomic classes with lower purchasing power. CONCLUSIONS: risk practices such as inadequate storage, manufacturing, and use of sanitizing products by the population evidence the need for public health policies, including educational measures, as a means of preventing accidents.

  5. 78 FR 59679 - Antimony Trioxide TSCA Chemical Risk Assessment; Notice of Public Meetings and Opportunity To...

    Science.gov (United States)

    2013-09-27

    ...EPA's contractor, The Scientific Consulting Group (SCG), Inc., has identified a panel of scientific experts to conduct a peer review of EPA's draft Toxic Substances Control Act (TSCA) chemical risk assessment, ``TSCA Workplan Chemical Risk Assessment for Antimony Trioxide.'' EPA will hold three peer review meetings by web connect and teleconference. EPA invites the public to register to attend the meetings as observers and/or speakers providing oral comments during any or all of the peer review meetings as discussed in this notice. The public may also provide comment on whether they believe the appearance of conflict of interest exists for any proposed peer review panel expert.

  6. Perceptions of environmental health risks among residents in the "Toxic Doughnut": opportunities for risk screening and community mobilization.

    Science.gov (United States)

    White, Brandi M; Hall, Eric S

    2015-12-10

    Surrounded by landfills, and toxic and hazardous facilities, Altgeld Gardens is located in a "toxic doughnut". With high rates of environmentally-related conditions, residents have called for a community-based environmental health assessment to improve overall health in their community. The purpose of this study was to investigate the attitudes and beliefs of environmental health risks of Altgeld's residents which would assist community organizing efforts and provide the groundwork for a community-based environmental health assessment. A questionnaire was designed and administered to 42 Altgeld residents who also participated in focus groups to assess their perceptions of environmental health risks. All participants were Altgeld residents for at least two years and were fairly representative of the broader community. Physical and social hazards were primarily identified as posing risks to participants' family and the broader community. Physical hazards included the dumping of hazardous waste and landfills; social hazards were crime and drugs. These findings have been useful in community organizing efforts and in program planning for local community-based organizations and public health agencies. The results have also been used to prioritize health and environmental risk issues impacting the community.

  7. Illicit drug use and HIV risk in the Dominican Republic: tourism areas create drug use opportunities.

    Science.gov (United States)

    Guilamo-Ramos, Vincent; Lee, Jane J; Ruiz, Yumary; Hagan, Holly; Delva, Marlyn; Quiñones, Zahira; Kamler, Alexandra; Robles, Gabriel

    2015-01-01

    While the Caribbean has the second highest global human immunodeficiency virus (HIV) prevalence, insufficient attention has been paid to contributing factors of the region's elevated risk. Largely neglected is the potential role of drugs in shaping the Caribbean HIV/acquired immune deficiency syndrome epidemic. Caribbean studies have almost exclusively focused on drug transportation and seldom acknowledged local user economies and drug-related health and social welfare consequences. While tourism is consistently implicated within the Caribbean HIV epidemic, less is known about the intersection of drugs and tourism. Tourism areas represent distinct ecologies of risk often characterised by sex work, alcohol consumption and population mixing between lower and higher risk groups. Limited understanding of availability and usage of drugs in countries such as the Dominican Republic (DR), the Caribbean country with the greatest tourist rates, presents barriers to HIV prevention. This study addresses this gap by conducting in-depth interviews with 30 drug users in Sosúa, a major sex tourism destination of the DR. A two-step qualitative data analysis process was utilised and interview transcripts were systematically coded using a well-defined thematic codebook. Results suggest three themes: (1) local demand shifts drug routes to tourism areas, (2) drugs shape local economies and (3) drug use facilitates HIV risk behaviours in tourism areas.

  8. 78 FR 34323 - Funding Opportunity Title: Risk Management Education in Targeted States (Targeted States Program)

    Science.gov (United States)

    2013-06-07

    ... electronically through rma.agrisk.umn.edu , must be received by close of business (COB) 11:59 p.m. EST. on July... strategic goals is to ensure that its customers are well-informed of risk management solutions available... Event of a Human Pandemic Outbreak (Pandemic Plan). RMA requires that project leaders submit a project...

  9. Energy finance to 2010: risks and opportunities for the industry and investors

    International Nuclear Information System (INIS)

    Nawaz, Sameer.

    1997-01-01

    Energy Finance to 2010, published by the Financial Times, covers all aspects of world wide energy finance. Topics reviewed in detail include an introduction to energy finance, energy infrastructure, private sector involvement, risk and precautions, the role of multilateral agencies, company investment strategies, and future trends and issues. (UK)

  10. Initiating Opportunities to Enhance Preservice Teachers' Pedagogical Knowledge: Perceptions about Mentoring At-Risk Adolescents

    Science.gov (United States)

    Garza, Ruben

    2012-01-01

    Providing preservice teachers in urban settings with authentic educational experiences may be an effective approach in preparing them to teach diverse students. Therefore, this investigation examined preservice teachers' perceptions of mentoring at-risk high school students. Data analysis reflected preservice teachers' positive experiences and…

  11. 78 FR 34377 - Trichloroethylene TSCA Chemical Risk Assessment; Notice of Public Meetings and Opportunity to...

    Science.gov (United States)

    2013-06-07

    ... ENVIRONMENTAL PROTECTION AGENCY [EPA-HQ-OPPT-2012-0723; FRL-9389-1] Trichloroethylene TSCA... Trichloroethylene: Degreaser and Arts/Crafts Uses.'' EPA will hold three peer review meetings by web connect and... Risk Assessment for Trichloroethylene: Degreaser and Arts/Crafts Uses.'' Trichloroethylene (TCE) (CASRN...

  12. Worksite Opportunities for Wellness (WOW): effects on cardiovascular disease risk factors after 1 year.

    Science.gov (United States)

    Racette, Susan B; Deusinger, Susan S; Inman, Cindi L; Burlis, Tamara L; Highstein, Gabrielle R; Buskirk, Trent D; Steger-May, Karen; Peterson, Linda R

    2009-01-01

    To evaluate the effectiveness of a worksite health promotion program on improving cardiovascular disease risk factors. In St Louis, Missouri from 2005 to 2006, 151 employees (134 F, 17 M, 81% overweight/obese) participated in a cohort-randomized trial comparing assessments + intervention (worksite A) with assessments only (worksite B) for 1 year. All participants received personal health reports containing their assessment results. The intervention was designed to promote physical activity and favorable dietary patterns using pedometers, healthy snack cart, WeightWatchers(R) meetings, group exercise classes, seminars, team competitions, and participation rewards. Outcomes included BMI, body composition, blood pressure, fitness, lipids, and Framingham 10-year coronary heart disease risk. 123 participants, aged 45+/-9 yr, with BMI 32.9+/-8.8 kg/m(2) completed 1 year. Improvements (P< or =0.05) were observed at both worksites for fitness, blood pressure, and total-, HDL-, and LDL-cholesterol. Additional improvements occurred at worksite A in BMI, fat mass, Framingham risk score, and prevalence of the metabolic syndrome; only the changes in BMI and fat mass were different between worksites. A multi-faceted worksite intervention promoted favorable changes in cardiovascular disease risk factors, but many of the improvements were achieved with worksite health assessments and personalized health reports in the absence of an intervention.

  13. 77 FR 21067 - Funding Opportunity Title: Risk Management Education and Outreach Partnerships Program

    Science.gov (United States)

    2012-04-09

    ..., crop insurance, marketing contracts, and other existing and emerging risk management tools.'' For the... Management or other similar topics. Legal: Legal and Succession Planning or other similar topics; Marketing... Management Education and Outreach Partnerships Program Announcement Type: Announcement of Availability of...

  14. Enterprise Risk Management Can Be a Strategic Opportunity. Perspectives…Presenting Thought Leaders' Points of View

    Science.gov (United States)

    Beasley, Mark S.

    2013-01-01

    Declining resources, new delivery models for education, questions regarding the value of research, issues surrounding athletics, physical security threats, and slowing demand for college graduates represent only a few of the risks on the horizon for colleges and universities. Higher education is transforming rapidly, creating both opportunities…

  15. Low emission feed : opportunities to mitigate enteric methane production of dairy cows

    NARCIS (Netherlands)

    Hatew, B.

    2015-01-01

    As global demand for high-quality food originating from animal production is expected to rise due to an increasing human population and consumer income level, the expected role of ruminants in meeting this demand brings multiple challenges. Ruminant production needs to adapt to environmental

  16. Employment Opportunities and Training Needs in Agribusiness. Competencies for Cotton Production in the United States.

    Science.gov (United States)

    Holcomb, John W.; And Others

    The competencies necessary for entry and advancement in cotton production were determined by surveying people in the cotton production industry from nine of the ten leading cotton producing states. A preliminary listing of competencies was developed from a review of the literature and from a survey of specialized personnel in soil and crop…

  17. Status and opportunities associated with product costing strategies in wood component manufacturing

    Science.gov (United States)

    Adrienn Andersch; Urs Buehlmann; Jan Wiedenbeck; Steve Lawser

    2013-01-01

    Product costing systems are critically important for businesses because they help reduce costs, price products at competitive prices, and enable strategic decisionmaking. This article reports the results of a survey designed to collect information about practices used by the North American hardwood dimension and components industry to calculate the cost of their...

  18. Marketing of specialty forest products in the southeast: opportunities for research, education and outreach (poster abstract)

    Science.gov (United States)

    A.L. Hammett; J.L. Chamberlain

    1999-01-01

    The specialty forest products sector in the Southeast is growing rapidly - perhaps faster than in other sections of the country. In 1993, the state of Virginia exported almost 10 percent of the national total of wild harvested ginseng. On a yearly basis, the value of the specialty forest products extracted from Virginia?s forests has been estimated at $35 million. The...

  19. Production of biofuels and biochemicals by in vitro synthetic biosystems: Opportunities and challenges.

    Science.gov (United States)

    Zhang, Yi-Heng Percival

    2015-11-15

    The largest obstacle to the cost-competitive production of low-value and high-impact biofuels and biochemicals (called biocommodities) is high production costs catalyzed by microbes due to their inherent weaknesses, such as low product yield, slow reaction rate, high separation cost, intolerance to toxic products, and so on. This predominant whole-cell platform suffers from a mismatch between the primary goal of living microbes - cell proliferation and the desired biomanufacturing goal - desired products (not cell mass most times). In vitro synthetic biosystems consist of numerous enzymes as building bricks, enzyme complexes as building modules, and/or (biomimetic) coenzymes, which are assembled into synthetic enzymatic pathways for implementing complicated bioreactions. They emerge as an alternative solution for accomplishing a desired biotransformation without concerns of cell proliferation, complicated cellular regulation, and side-product formation. In addition to the most important advantage - high product yield, in vitro synthetic biosystems feature several other biomanufacturing advantages, such as fast reaction rate, easy product separation, open process control, broad reaction condition, tolerance to toxic substrates or products, and so on. In this perspective review, the general design rules of in vitro synthetic pathways are presented with eight supporting examples: hydrogen, n-butanol, isobutanol, electricity, starch, lactate,1,3-propanediol, and poly-3-hydroxylbutyrate. Also, a detailed economic analysis for enzymatic hydrogen production from carbohydrates is presented to illustrate some advantages of this system and the remaining challenges. Great market potentials will motivate worldwide efforts from multiple disciplines (i.e., chemistry, biology and engineering) to address the remaining obstacles pertaining to cost and stability of enzymes and coenzymes, standardized building parts and modules, biomimetic coenzymes, biosystem optimization, and scale

  20. Hot business - cool opportunities

    International Nuclear Information System (INIS)

    Fraser, M.

    1997-01-01

    A new role for the deregulated electric utilities in the energy services market or performance contracting markets was discussed. It was argued that in view of the long tradition of close customer contact, distribution utilities are in a good position to leverage their relationship with their customers to expand the range of products and services that the ''utility'' provides to them. Real time pricing, energy services, HVAC maintenance and operation are just some of the areas where the distribution utility''s linkage to customers could be used to good advantage. Some case histories, and a list of potential product and service opportunities in the commercial/industrial and residential sectors were provided. Some of the potential pitfalls were also identified for utilities that wish to pursue these opportunities. These pitfalls included legal, marketing, risk management and funding issues

  1. A framework for risk assessment on lean production implementation

    Directory of Open Access Journals (Sweden)

    Giuliano Almeida Marodin

    2014-02-01

    Full Text Available The organizational and technical complexity of implementing the lean principles and practices can become an extensively time consuming journey with few benefits. We argue that risk assessment can aid on the understanding and management of the major difficulties on the Lean production implementation (LPI. Thus, this paper proposes a framework for risk assessment on the LPI process. The literature review permitted to adapt the risk assessment steps to the characteristics of the LPI and develop data collection and analysis procedures for each step. The Sociotechnical systems (STS theory was brought in to improve the understanding of the context’s characteristics on the proposed framework because it has a major influence on the LPI. The framework was has five steps: (a defining the unit of analysis; (b describing the context; (c risk identification; (d risk analysis; and (e risk relationships modeling.

  2. Risk communication related to animal products derived from biotechnology.

    Science.gov (United States)

    McCrea, D

    2005-04-01

    Previous chapters of this review have dealt with the key considerations related to the application of biotechnology in veterinary science and animal production. This article explores the theory and practice of risk communication and sets out the basic principles for good risk communication when dealing with new technologies, uncertainty, and cautious and sceptical consumers. After failure to communicate with consumers and stakeholders about the risk to human health from bovine spongiform encephalopathy (BSE) in the 1990s, Government Agencies in the United Kingdom have made significant improvements in risk communication. The official inquiry that followed the BSE crisis concluded that a policy of openness was the correct approach, and this article emphasises the importance of consultation, consistency and transparency. There are, however, many different factors that affect public perception of risk (religious, political, social, cultural, etc.) and developing effective risk communication strategies must take all of these complex issues into consideration.

  3. Exploiting Nutritional Value of Staple Foods in the World’s Semi-Arid Areas: Risks, Benefits, Challenges and Opportunities of Sorghum

    Directory of Open Access Journals (Sweden)

    Ilaria Proietti

    2015-03-01

    Full Text Available Sorghum (Sorghum bicolor (L. Moench is a drought-resistant crop and an important food resource in terms of nutritional as well as social-economic values, especially in semi-arid environments. Cultivar selection and processing methods have been observed to impact on composition and functional and nutritional value of sorghum. Amino acid imbalance, cyanogenic glycosides, endogenous anti-nutrients, mycotoxins and toxic elements are among factors impairing its nutritional value. This paper reviews possible approaches (varieties selection, production practices, cooking processes to improve the benefits-to-risks balance of sorghum meal, to mitigate the risk of deficiencies and/or imbalances and to improve effects on human nutrition. Opportunity for avoiding dietary diversification in high sorghum consumers is also discussed, e.g., tryptophan and niacin deficits potentially related to pellagra, or unavailability of proteins and divalent cations (e.g., Fe, Zn due to the antinutrient activity of phytic acid and tannins. As potential candidate for production investments, the role of sorghum in preserving biological diversity is also considered.

  4. Health Risk Assessment on Hazardous Ingredients in Household Deodorizing Products

    Directory of Open Access Journals (Sweden)

    Minjin Lee

    2018-04-01

    Full Text Available The inhalation of a water aerosol from a humidifier containing disinfectants has led to serious lung injuries in Korea. To promote the safe use of products, the Korean government enacted regulations on the chemicals in various consumer products that could have adverse health effects. Given the concern over the potential health risks associated with the hazardous ingredients in deodorizing consumer products, 17 ingredients were analyzed and assessed according to their health risk on 3 groups by the application type in 47 deodorizing products. The risk assessment study followed a stepwise procedure (e.g., collecting toxicological information, hazard identification/exposure assessment, and screening and detailed assessment for inhalation and dermal routes. The worst-case scenario and maximum concentration determined by the product purpose and application type were used as the screening assessment. In a detailed assessment, the 75th exposure factor values were used to estimate the assumed reasonable exposure to ingredients. The exposed concentrations of seven ingredients were calculated. Due to limitation of toxicity information, butylated hydroxyl toluene for a consumer’s exposure via the dermal route only was conducted for a detailed assessment. This study showed that the assessed ingredients have no health risks at their maximum concentrations in deodorizing products. This approach can be used to establish guidelines for ingredients that may pose inhalation and dermal hazards.

  5. Health Risk Assessment on Hazardous Ingredients in Household Deodorizing Products

    Science.gov (United States)

    Lee, Minjin; Kim, Joo-Hyon; Lee, Daeyeop; Kim, Jaewoo; Lim, Hyunwoo; Seo, Jungkwan; Park, Young-Kwon

    2018-01-01

    The inhalation of a water aerosol from a humidifier containing disinfectants has led to serious lung injuries in Korea. To promote the safe use of products, the Korean government enacted regulations on the chemicals in various consumer products that could have adverse health effects. Given the concern over the potential health risks associated with the hazardous ingredients in deodorizing consumer products, 17 ingredients were analyzed and assessed according to their health risk on 3 groups by the application type in 47 deodorizing products. The risk assessment study followed a stepwise procedure (e.g., collecting toxicological information, hazard identification/exposure assessment, and screening and detailed assessment for inhalation and dermal routes). The worst-case scenario and maximum concentration determined by the product purpose and application type were used as the screening assessment. In a detailed assessment, the 75th exposure factor values were used to estimate the assumed reasonable exposure to ingredients. The exposed concentrations of seven ingredients were calculated. Due to limitation of toxicity information, butylated hydroxyl toluene for a consumer’s exposure via the dermal route only was conducted for a detailed assessment. This study showed that the assessed ingredients have no health risks at their maximum concentrations in deodorizing products. This approach can be used to establish guidelines for ingredients that may pose inhalation and dermal hazards. PMID:29652814

  6. Risks and opportunities for emerging markets: The cases of India and China

    Directory of Open Access Journals (Sweden)

    Sanjay Peters

    2010-04-01

    Full Text Available Nowadays, the re-emergence of China and India as influential economic powers is commonly accepted as a fact. However, the path taken by each of the two countries over the past 15 years in order for them to reach the highest growth rates in the world has been quite different. In the case of China, much of the macroeconomic growth can be attributed (at least from the 1990s onwards to Foreign Direct Investment (FDI. In India, meanwhile, the organic or autonomous development of businesses and consumption are the two main factors that have boosted the growth of GDP. Based on this premise, this article enumerates and explores the main economic, political, environmental and social challenges that must be dealt with in each case, thus presenting a panoramic view of each country’s impending economic and political agenda. Finally, and by way of a conclusion, the article tackles the most important challenges and opportunities for investment in the two countries.

  7. Collaboration and Co-Production of Knowledge in Healthcare: Opportunities and Challenges

    Directory of Open Access Journals (Sweden)

    Jo Rycroft-Malone

    2016-04-01

    Full Text Available Over time there has been a shift, at least in the rhetoric, from a pipeline conceptualisation of knowledge implementation, to one that recognises the potential of more collaboration, co-productive approaches to knowledge production and use. In this editorial, which is grounded in our research and collective experience, we highlight both the potential and challenge with collaboration and co-production. This includes issues about stakeholder engagement, governance arrangements, and capacity and capability for working in a coproductive way. Finally, we reflect on the fact that this approach is not a panacea, but is accompanied by some philosophical and practical challenges.

  8. The fungal resistome: a risk and an opportunity for the development of novel antifungal therapies.

    Science.gov (United States)

    Reales-Calderón, Jose A; Molero, Gloria; Gil, Concha; Martínez, José L

    2016-08-01

    The risks for toxicity of novel antifungal compounds, together with the emergence of resistance, makes the use of inhibitors of resistance, in combination with antifungal compounds, a suitable strategy for developing novel antifungal formulations. Among them, inhibitors of efflux pumps are suitable candidates. Increasing drug influx or interfering with the stress response may also improve the efficacy of antifungals. Therapies as induction of fungal apoptosis or immunostimulation are also good strategies for reducing the risks for resistance and to improve antifungals' efficacy. Understanding the effect of the acquisition of resistance on the fungal physiology and determining the collateral sensitivity networks are useful for the development of novel strategies based on combination of antifungals for improving the efficacy of the therapy.

  9. Implementing systematic review techniques in chemical risk assessment: Challenges, opportunities and recommendations.

    Science.gov (United States)

    Whaley, Paul; Halsall, Crispin; Ågerstrand, Marlene; Aiassa, Elisa; Benford, Diane; Bilotta, Gary; Coggon, David; Collins, Chris; Dempsey, Ciara; Duarte-Davidson, Raquel; FitzGerald, Rex; Galay-Burgos, Malyka; Gee, David; Hoffmann, Sebastian; Lam, Juleen; Lasserson, Toby; Levy, Len; Lipworth, Steven; Ross, Sarah Mackenzie; Martin, Olwenn; Meads, Catherine; Meyer-Baron, Monika; Miller, James; Pease, Camilla; Rooney, Andrew; Sapiets, Alison; Stewart, Gavin; Taylor, David

    2016-01-01

    Systematic review (SR) is a rigorous, protocol-driven approach designed to minimise error and bias when summarising the body of research evidence relevant to a specific scientific question. Taking as a comparator the use of SR in synthesising research in healthcare, we argue that SR methods could also pave the way for a "step change" in the transparency, objectivity and communication of chemical risk assessments (CRA) in Europe and elsewhere. We suggest that current controversies around the safety of certain chemicals are partly due to limitations in current CRA procedures which have contributed to ambiguity about the health risks posed by these substances. We present an overview of how SR methods can be applied to the assessment of risks from chemicals, and indicate how challenges in adapting SR methods from healthcare research to the CRA context might be overcome. Regarding the latter, we report the outcomes from a workshop exploring how to increase uptake of SR methods, attended by experts representing a wide range of fields related to chemical toxicology, risk analysis and SR. Priorities which were identified include: the conduct of CRA-focused prototype SRs; the development of a recognised standard of reporting and conduct for SRs in toxicology and CRA; and establishing a network to facilitate research, communication and training in SR methods. We see this paper as a milestone in the creation of a research climate that fosters communication between experts in CRA and SR and facilitates wider uptake of SR methods into CRA. Copyright © 2015 The Authors. Published by Elsevier Ltd.. All rights reserved.

  10. Development of hydrate risk quantification in oil and gas production

    Science.gov (United States)

    Chaudhari, Piyush N.

    Subsea flowlines that transport hydrocarbons from wellhead to the processing facility face issues from solid deposits such as hydrates, waxes, asphaltenes, etc. The solid deposits not only affect the production but also pose a safety concern; thus, flow assurance is significantly important in designing and operating subsea oil and gas production. In most subsea oil and gas operations, gas hydrates form at high pressure and low temperature conditions, causing the risk of plugging flowlines, with a undesirable impact on production. Over the years, the oil and gas industry has shifted their perspective from hydrate avoidance to hydrate management given several parameters such as production facility, production chemistry, economic and environmental concerns. Thus, understanding the level of hydrate risk associated with subsea flowlines is an important in developing efficient hydrate management techniques. In the past, hydrate formation models were developed for various flow-systems (e.g., oil dominated, water dominated, and gas dominated) present in the oil and gas production. The objective of this research is to extend the application of the present hydrate prediction models for assessing the hydrate risk associated with subsea flowlines that are prone to hydrate formation. It involves a novel approach for developing quantitative hydrate risk models based on the conceptual models built from the qualitative knowledge obtained from experimental studies. A comprehensive hydrate risk model, that ranks the hydrate risk associated with the subsea production system as a function of time, hydrates, and several other parameters, which account for inertial, viscous, interfacial forces acting on the flow-system, is developed for oil dominated and condensate systems. The hydrate plugging risk for water dominated systems is successfully modeled using The Colorado School of Mines Hydrate Flow Assurance Tool (CSMHyFAST). It is found that CSMHyFAST can be used as a screening tool in

  11. Risk factors for secondary substance use disorders in people with childhood and adolescent-onset bipolar disorder: opportunities for prevention.

    Science.gov (United States)

    Kenneson, Aileen; Funderburk, Jennifer S; Maisto, Stephen A

    2013-07-01

    Compared to other mental illnesses, bipolar disorder is associated with a disproportionately high rate of substance use disorders (SUDs), and the co-occurrence is associated with significant morbidity and mortality. Early diagnosis of primary bipolar disorder may provide opportunities for SUD prevention, but little is known about the risk factors for secondary SUD among individuals with bipolar disorder. The purposes of this study were to describe the population of people with childhood and adolescent-onset primary bipolar disorder, and to identify risk factors for secondary SUD in this population. Using data collected from the National Comorbidity Survey Replication study, we identified 158 individuals with childhood-onset (adolescent-onset (13-18 years) primary bipolar disorder (I, II or subthreshold). Survival analysis was used to identify risk factors for SUD. Compared to adolescent-onset, people with childhood-onset bipolar disorder had increased likelihoods of attention deficit hyperactivity disorder (ADHD) (adjusted odds ratio=2.81) and suicide attempt (aOR=3.61). Males were more likely than females to develop SUD, and did so at a faster rate. Hazard ratios of risk factors for SUD were: lifetime oppositional defiant disorder (2.048), any lifetime anxiety disorder (3.077), adolescent-onset bipolar disorder (1.653), and suicide attempt (15.424). SUD was not predicted by bipolar disorder type, family history of bipolar disorder, hospitalization for a mood episode, ADHD or conduct disorder. As clinicians struggle to help individuals with bipolar disorder, this study provides information that might be useful in identifying individuals at higher risk for SUD. Future research can examine whether targeting these risk factors may help prevent secondary SUD. Published by Elsevier Inc.

  12. Climate Change, Risk and Grain Production in China

    OpenAIRE

    Holst, Rainer; Yu, Xiaohua; Grun, Carola

    2010-01-01

    This paper employs the production function-based method proposed by Just and Pope (1978, 1979) to explicitly analyze production risk in the context of Chinese grain farming and climate change, and test for potential endogeneity of climate factors in Chinese grain production. Our results indicate that grain production in south China might, at least in the short run, could be a net beneficiary of global warming. In particular, we find that a 1 °C increase in annual average temperature in South ...

  13. 75 FR 8909 - Funding Opportunity Title: Commodity Partnerships for Small Agricultural Risk Management...

    Science.gov (United States)

    2010-02-26

    ... agreement program is to deliver training and information in management of production, marketing, and... ``* * * producers will be better able to use financial management, crop insurance, marketing contracts, and other... to use financial management, crop insurance, marketing contracts, and other existing and emerging...

  14. OPPORTUNITIES TO PROMOTE ROMANIAN AGRO-FOOD PRODUCTS TO NON-EUROPEAN MARKETS

    Directory of Open Access Journals (Sweden)

    Zanvetor Raffaella

    2014-07-01

    Through participation at events, fairs and exhibitions of national and international importance , in particular by means of stands aimed at enhancing the image of Community products , Romanian exports to non -EU area will grow considerably in the coming years.

  15. Design for Environment: opportunities in supply chain network and product design

    OpenAIRE

    Chen, Yifen

    2013-01-01

    This dissertation contributes to the sustainability literature by incorporating a systematic analysis to provide guidelines to sustainable design. During the design phase, there is a great potential to manage the environmental impacts of the whole product life cycle. However, decision making in the design phase is usually complicated. Therefore, a holistic system analysis with the consideration of relevant factors in the whole product life cycle is needed. In this dissertation, a life-cycle t...

  16. Grassland futures in Great Britain - Productivity assessment and scenarios for land use change opportunities.

    Science.gov (United States)

    Qi, Aiming; Holland, Robert A; Taylor, Gail; Richter, Goetz M

    2018-09-01

    To optimise trade-offs provided by future changes in grassland use intensity, spatially and temporally explicit estimates of respective grassland productivities are required at the systems level. Here, we benchmark the potential national availability of grassland biomass, identify optimal strategies for its management, and investigate the relative importance of intensification over reversion (prioritising productivity versus environmental ecosystem services). Process-conservative meta-models for different grasslands were used to calculate the baseline dry matter yields (DMY; 1961-1990) at 1km 2 resolution for the whole UK. The effects of climate change, rising atmospheric [CO 2 ] and technological progress on baseline DMYs were used to estimate future grassland productivities (up to 2050) for low and medium CO 2 emission scenarios of UKCP09. UK benchmark productivities of 12.5, 8.7 and 2.8t/ha on temporary, permanent and rough-grazing grassland, respectively, accounted for productivity gains by 2010. By 2050, productivities under medium emission scenario are predicted to increase to 15.5 and 9.8t/ha on temporary and permanent grassland, respectively, but not on rough grassland. Based on surveyed grassland distributions for Great Britain in 2010 the annual availability of grassland biomass is likely to rise from 64 to 72milliontonnes by 2050. Assuming optimal N application could close existing productivity gaps of ca. 40% a range of management options could deliver additional 21∗10 6 tonnes of biomass available for bioenergy. Scenarios of changes in grassland use intensity demonstrated considerable scope for maintaining or further increasing grassland production and sparing some grassland for the provision of environmental ecosystem services. Copyright © 2018 The Authors. Published by Elsevier B.V. All rights reserved.

  17. Biotechnological opportunities to biopolymers production. Oportunidades biotecnologicas para la produccion de biopolimeros

    Energy Technology Data Exchange (ETDEWEB)

    Ballesteros, M; Ballesteros, I; Oliva, J M [Instituto de Energias Renovables, CIEMAT, Madrid (Spain)

    1994-01-01

    The increasing garbage mountain is more and more recognized as an ecological threat, Space for landfills is limited and additional Incineration capacities require high capital investments and pose additional environmental problems. This paper discusses the current development and utilization state of new biodegradable polymers. Special attention is focused on microbiological production of poli-D-Beta-hydroxybutyrate acid (PHB), reviewing the metabolic regulation of PHB and the elements to determine its industrial scale production. (Author) 6 refs.

  18. Principle considerations for the risk assessment of sprayed consumer products.

    Science.gov (United States)

    Steiling, W; Bascompta, M; Carthew, P; Catalano, G; Corea, N; D'Haese, A; Jackson, P; Kromidas, L; Meurice, P; Rothe, H; Singal, M

    2014-05-16

    In recent years, the official regulation of chemicals and chemical products has been intensified. Explicitly for spray products enhanced requirements to assess the consumers'/professionals' exposure to such product type have been introduced. In this regard the Aerosol-Dispensers-Directive (75/324/EEC) with obligation for marketing aerosol dispensers, and the Cosmetic-Products-Regulation (1223/2009/EC) which obliges the insurance of a safety assessment, have to be mentioned. Both enactments, similar to the REACH regulation (1907/2006/EC), require a robust chemical safety assessment. From such assessment, appropriate risk management measures may be identified to adequately control the risk of these chemicals/products to human health and the environment when used. Currently, the above-mentioned regulations lack the guidance on which data are needed for preparing a proper hazard analysis and safety assessment of spray products. Mandatory in the process of inhalation risk and safety assessment is the determination and quantification of the actual exposure to the spray product and more specifically, its ingredients. In this respect the current article, prepared by the European Aerosol Federation (FEA, Brussels) task force "Inhalation Toxicology", intends to introduce toxicological principles and the state of the art in currently available exposure models adapted for typical application scenarios. This review on current methodologies is intended to guide safety assessors to better estimate inhalation exposure by using the most relevant data. Copyright © 2014 The Authors. Published by Elsevier Ireland Ltd.. All rights reserved.

  19. The Water-Energy-Food Nexus: Climate Risks and Opportunities in Southern Africa

    Directory of Open Access Journals (Sweden)

    Luxon Nhamo

    2018-04-01

    Full Text Available The discourse on the need for water, energy, and food security has dominated the development agenda of southern African countries, centred on improving livelihoods, building resilience, and regional integration. About 60% of the population in the Southern African Development Community (SADC live in rural areas relying mainly on rainfed agriculture, lacking access to clean water and energy, yet the region is endowed with vast natural resources. The water-energy-food (WEF nexus is a conceptual framework that presents opportunities for greater resource coordination, management, and policy convergence across sectors. This is particularly relevant in the SADC region as resources are transboundary and supports efforts linked to regional integration and inclusive socio-economic development and security. We conducted an appraisal of WEF-related policies and institutions in SADC and identified linkages among them. The present ‘silo’ approach in resource management and allocation, often conducted at the national level, contributes to the region’s failure to meet its development targets, exacerbating its vulnerabilities. The lack of coordination of WEF nexus synergies and trade-offs in planning often threatens the sustainability of development initiatives. We highlighted the importance of the WEF nexus to sustainably address the sectoral coordination of resources through harmonised institutions and policies, as well as setting targets and indicators to direct and monitor nexus developments. We illustrate the significance of the nexus in promoting inclusive development and transforming vulnerable communities into resilient societies. The study recommends a set of integrated assessment models to monitor and evaluate the implementation of WEF nexus targets. Going forward, we propose the adoption of a regional WEF nexus framework.

  20. Risk management of Norwegian oil production; Risikostyring av norsk oljeproduksjon

    Energy Technology Data Exchange (ETDEWEB)

    Kloegetvedt, Bjoern

    1998-07-01

    The items discussed in this presentation are: (1) Oil price chronology, (2) Market structure - Forward prices, (3) Volatility in oil prices, (4) Sales strategies and price fixing, (5) Development of ''Risk Management'' in the oil trading, (6) Oil products and markets, (7) Management of risk exposure, (8) Strong points and weak points of the norm price system, (9) Comparison with UK.

  1. Opportunity Design

    DEFF Research Database (Denmark)

    Nielsen, Louise Møller; Lassen, Astrid Heidemann; Tollestrup, Christian

    2012-01-01

    Creating and growing new businesses is basically about turning an entrepreneurial opportunity into future business. In literature the emergence of opportunities is often described as opportunity recognition or opportunity discovery, which points to the understanding that opportunities are out the...

  2. Evaluation of the Risk and of the Opportunities in Launching the New Banking Services

    Directory of Open Access Journals (Sweden)

    Iuliana Cetina

    2007-09-01

    Full Text Available The creation of new products and services is acknowledged as being a necessity for thedevelopment of a company. Furthermore, due to the changes occurred in the banking field, the introductionof new services became for institutions a condition to remain competitive.The banking institutions which intend to be leaders in a domain should take the initiative andintroduce new services. In the same measure, there are companies for which the cost of a potential failureis too high and they cannot allow it. They limit to introduce in their offer the products that have beentested on the market and have success among the consumers. This option in the marketing policy of thefirm depends on several factors, such as the mission of the organisation, the intended objectives, thedimension and the resources of which it disposes and last but not least the nature of the new proposedservice.

  3. Norovirus Infection in Older Adults: Epidemiology, Risk Factors, and Opportunities for Prevention and Control.

    Science.gov (United States)

    Cardemil, Cristina V; Parashar, Umesh D; Hall, Aron J

    2017-12-01

    Norovirus is the leading cause of acute gastroenteritis. In older adults, it is responsible for an estimated 3.7 million illnesses; 320,000 outpatient visits; 69,000 emergency department visits; 39,000 hospitalizations; and 960 deaths annually in the United States. Older adults are particularly at risk for severe outcomes, including prolonged symptoms and death. Long-term care facilities and hospitals are the most common settings for norovirus outbreaks in developed countries. Diagnostic platforms are expanding. Several norovirus vaccines in clinical trials have the potential to reap benefits. This review summarizes current knowledge on norovirus infection in older adults. Published by Elsevier Inc.

  4. Shale Gas Development in the Central Karoo: A Scientific Assessment of the Opportunities and Risks

    CSIR Research Space (South Africa)

    Scholes, B

    2016-11-01

    Full Text Available Processes, Ecosystems and Species Ch 8 Impacts on Agriculture Ch 9 Impact on Tourism in the Karoo Ch 10 Impacts on the Economy Ch 11 Impacts on Social Fabric of 34 Municipalities Ch 12 Impact on Human Health Ch 13 Impact on Sense of Place Values Ch 14... process, is an approach for 7 considering all aspects of an issue in a common way, and in a spatial context. Risk is determined by 8 estimating the likelihood of events or trends occurring, in relation to their consequences (Figure 5). 9 10 11...

  5. [Renal biopsy in the lateral position in high risk patients: an opportunity to take advantage of].

    Science.gov (United States)

    Dugo, Mauro; Brisotto, Elisa; Vitturi, Nicola; Pasi, Alessandra; Mastrosimone, Stefania; Farneti, Fabrizio; Mangino, Margherita; Virgilio, Bice; Brunello, Anna; Pastori, Giordano; Mazzoli, Matteo; Laurino, Licia; Cova, Giandavide; Beniamin, Francesco; Maresca, Maria Cristina

    2015-01-01

    Percutaneous ultrasound-guided renal biopsy (RB) is the gold standard for diagnosis of renal diseases. The standard procedure involves biopsy in the prone position (PP) for the native kidneys. In high risk patients, transjugular and laparoscopic RB have been proposed. In patients suffering from obesity or respiratory diseases, the RB of the native kidney in the supine anterolateral position (SALP) represents an alternative to these invasive and expensive methods. We illustrate the technique of execution of RB in the lateral position (LP) on native kidneys. The procedure is safe, effective and has reduced the path travelled by the needle biopsy compared with PP and SALP.

  6. Livestock, the World, and the Dutch : a quick scan of opportunities in livestock production in nine countries : final draft for discussion

    NARCIS (Netherlands)

    Lee, van der J.; Hooft, van 't K.; Cornelissen, J.M.R.; Wouters, A.P.

    2013-01-01

    This report explores opportunities and associated challenges for companies and organizations engaged in livestock production and marketing by looking at nine countries, representing BRIC countries, the so-called Next 11, and developing countries.

  7. Out of Unemployment? A Comparative Analysis of the Risks and Opportunities Longer-Term Unemployed Immigrant Youth Face when Entering the Labour Market

    Science.gov (United States)

    Malmberg-Heimonen, Ira; Julkunen, Ilse

    2006-01-01

    Because of high unemployment rates among youth in Europe, comparative research has focused on identification of those risks and opportunities associated with the integration process from unemployment to work. The integration process of immigrant youth, however, received much less attention, despite their initially higher risk of unemployment than…

  8. A risk analysis for production processes with disposable bioreactors.

    Science.gov (United States)

    Merseburger, Tobias; Pahl, Ina; Müller, Daniel; Tanner, Markus

    2014-01-01

    : Quality management systems are, as a rule, tightly defined systems that conserve existing processes and therefore guarantee compliance with quality standards. But maintaining quality also includes introducing new enhanced production methods and making use of the latest findings of bioscience. The advances in biotechnology and single-use manufacturing methods for producing new drugs especially impose new challenges on quality management, as quality standards have not yet been set. New methods to ensure patient safety have to be established, as it is insufficient to rely only on current rules. A concept of qualification, validation, and manufacturing procedures based on risk management needs to be established and realized in pharmaceutical production. The chapter starts with an introduction to the regulatory background of the manufacture of medicinal products. It then continues with key methods of risk management. Hazards associated with the production of medicinal products with single-use equipment are described with a focus on bioreactors, storage containers, and connecting devices. The hazards are subsequently evaluated and criteria for risk evaluation are presented. This chapter concludes with aspects of industrial application of quality risk management.

  9. Natural gas for electric power generation: Strategic issues, risks and opportunities

    International Nuclear Information System (INIS)

    Linderman, C.

    1992-01-01

    Natural gas is again being regarded as a significant fuel for electric power generation. It was once a predominant fuel for utilities in gas-producing areas, but natural gas consumption declined greatly after the 1973 oil shock because of reduced electricity demand and increased coal and nuclear generation. Moreover, wellhead price and other forms of regulation produced gas shortages in the 1970s. The resurgence of natural gas in future resource plans stems from its inherent ideal fuel characteristics: short lead time; low capital costs; small increments of modular capacity; delivered close to load centers; environmentally benign, preferable to oil and coal; and potential for high thermal efficiency in gas turbines. Natural gas, if available and attractively priced, is an ideal fuel for electric power generation. No other fuel shares these attractive characteristics, and utilities, facing higher than expected load growth, are relying on an increasing proportion of gas-fired combustion turbines, combined cycle plants, and cogeneration to meet a growing, yet uncertain, future demand for electricity. Despite these desirable operating characteristics, the varied past and uncertain future of natural gas markets raise legitimate concerns about the riskiness of current utility natural gas strategies. This report, which summarizes the major findings from research efforts, is intended to help utility decision-makers understand the full range of risks they face with natural gas electric power generation and to identify actions they can take to mitigate those risks

  10. Tourist ships on the Danube as an opportunity for export of meat and meat products

    Directory of Open Access Journals (Sweden)

    Tešanović Dragan

    2015-01-01

    Full Text Available Tourism development launches growth of other complementary industries. River tourism, as a special selective tourism form, experiences intensive development, with an importance for all the regions through which the Danube, as an integral part of the Rhine - Main - Danube waterway, flows. During cruising, the largest consumption is achieved on the ship itself, where meat and meat products are an integral element of every meal and represent the most expensive component of the dish. The task of this paper is to analyse the consumption of meat and meat products on six tourist ships run by to 'Grand Circle Corporation' in 2013, in order to point out the possibility of supplying them with meat and meat products from sources in the territory where the ships sail. The paper presents the current suppliers and manufacturers of meat and meat products in Republic of Serbia that could supply the company 'Grand Circle Cruise Line' and other tourist ships that cruise on the Danube. Also, the research indicates that the export of meat products from the Republic Serbia could have a significant effect on improving the agricultural conditions and food production through increased competition, assuming the Serbian manufacturers supply most of tourist ships and not only the six ships analysed in this paper. Research results, specifically, point out the possibility of increasing export of poultry and beef if the potential demand of each of the eight companies with their 54 ships which operate tourist cruises on the Danube is taken into account. The data have been systematized, analysed and presented statistically in tables and graphs.

  11. Study of medicine 2.0 due to Web 2.0?! - Risks and opportunities for the curriculum in Leipzig

    Science.gov (United States)

    Hempel, Gunther; Neef, Martin; Rotzoll, Daisy; Heinke, Wolfgang

    2013-01-01

    Web 2.0 is changing the study of medicine by opening up totally new ways of learning and teaching in an ongoing process. Global social networking services like Facebook, YouTube, Flickr, Google Drive and Xing already play an important part in communication both among students and between students and teaching staff. Moreover, local portals (such as the platform [http://www.leipzig-medizin.de] established in 2003) have also caught on and in some cases eclipsed the use of the well-known location-independent social media. The many possibilities and rapid changes brought about by social networks need to be publicized within medical faculties. Therefore, an E-learning and New Media Working Group was set up at the Faculty of Medicine of Universität Leipzig in order to harness the opportunities of Web 2.0, analyse the resulting processes of change in the study of medicine, and curb the risks of the Internet. With Web 2.0 and the social web already influencing the study of medicine, the opportunities of the Internet now need to be utilized to improve the teaching of medicine. PMID:23467440

  12. Study of medicine 2.0 due to Web 2.0?! -- risks and opportunities for the curriculum in Leipzig.

    Science.gov (United States)

    Hempel, Gunther; Neef, Martin; Rotzoll, Daisy; Heinke, Wolfgang

    2013-01-01

    Web 2.0 is changing the study of medicine by opening up totally new ways of learning and teaching in an ongoing process. Global social networking services like Facebook, YouTube, Flickr, Google Drive and Xing already play an important part in communication both among students and between students and teaching staff. Moreover, local portals (such as the platform [http://www.leipzig-medizin.de] established in 2003) have also caught on and in some cases eclipsed the use of the well-known location-independent social media. The many possibilities and rapid changes brought about by social networks need to be publicized within medical faculties. Therefore, an E-learning and New Media Working Group was set up at the Faculty of Medicine of Universität Leipzig in order to harness the opportunities of Web 2.0, analyse the resulting processes of change in the study of medicine, and curb the risks of the Internet. With Web 2.0 and the social web already influencing the study of medicine, the opportunities of the Internet now need to be utilized to improve the teaching of medicine.

  13. Flood risk management in Italy: challenges and opportunities for the implementation of the EU Floods Directive (2007/60/EC)

    Science.gov (United States)

    Mysiak, J.; Testella, F.; Bonaiuto, M.; Carrus, G.; De Dominicis, S.; Ganucci Cancellieri, U.; Firus, K.; Grifoni, P.

    2013-11-01

    Italy's recent history is punctuated with devastating flood disasters claiming high death toll and causing vast but underestimated economic, social and environmental damage. The responses to major flood and landslide disasters such as the Polesine (1951), Vajont (1963), Firenze (1966), Valtelina (1987), Piedmont (1994), Crotone (1996), Sarno (1998), Soverato (2000), and Piedmont (2000) events have contributed to shaping the country's flood risk governance. Insufficient resources and capacity, slow implementation of the (at that time) novel risk prevention and protection framework, embodied in the law 183/89 of 18 May 1989, increased the reliance on the response and recovery operations of the civil protection. As a result, the importance of the Civil Protection Mechanism and the relative body of norms and regulation developed rapidly in the 1990s. In the aftermath of the Sarno (1998) and Soverato (2000) disasters, the Department for Civil Protection (DCP) installed a network of advanced early warning and alerting centres, the cornerstones of Italy's preparedness for natural hazards and a best practice worth following. However, deep convective clouds, not uncommon in Italy, producing intense rainfall and rapidly developing localised floods still lead to considerable damage and loss of life that can only be reduced by stepping up the risk prevention efforts. The implementation of the EU Floods Directive (2007/60/EC) provides an opportunity to revise the model of flood risk governance and confront the shortcomings encountered during more than 20 yr of organised flood risk management. This brief communication offers joint recommendations towards this end from three projects funded by the 2nd CRUE ERA-NET (http://www.crue-eranet.net/) Funding Initiative: FREEMAN, IMRA and URFlood.

  14. Opportunities for Bio-Based Solvents Created as Petrochemical and Fuel Products Transition towards Renewable Resources.

    Science.gov (United States)

    Clark, James H; Farmer, Thomas J; Hunt, Andrew J; Sherwood, James

    2015-07-28

    The global bio-based chemical market is growing in size and importance. Bio-based solvents such as glycerol and 2-methyltetrahydrofuran are often discussed as important introductions to the conventional repertoire of solvents. However adoption of new innovations by industry is typically slow. Therefore it might be anticipated that neoteric solvent systems (e.g., ionic liquids) will remain niche, while renewable routes to historically established solvents will continue to grow in importance. This review discusses bio-based solvents from the perspective of their production, identifying suitable feedstocks, platform molecules, and relevant product streams for the sustainable manufacturing of conventional solvents.

  15. Opportunities for Bio-Based Solvents Created as Petrochemical and Fuel Products Transition towards Renewable Resources

    Science.gov (United States)

    Clark, James H.; Farmer, Thomas J.; Hunt, Andrew J.; Sherwood, James

    2015-01-01

    The global bio-based chemical market is growing in size and importance. Bio-based solvents such as glycerol and 2-methyltetrahydrofuran are often discussed as important introductions to the conventional repertoire of solvents. However adoption of new innovations by industry is typically slow. Therefore it might be anticipated that neoteric solvent systems (e.g., ionic liquids) will remain niche, while renewable routes to historically established solvents will continue to grow in importance. This review discusses bio-based solvents from the perspective of their production, identifying suitable feedstocks, platform molecules, and relevant product streams for the sustainable manufacturing of conventional solvents. PMID:26225963

  16. Gut immunity: Its development and reasons and opportunities for modulation in monogastric production animals

    Science.gov (United States)

    The intestine must perform the critical role of nutrient acquisition whilst preventing the passage of undesirable microbes or microbial products from the external environment to sterile body compartments. Various components contribute to antimicrobial defenses in the intestine. The mucus layer(s),...

  17. The economics of cyanobacteria-based biofuel production: challenges and opportunities

    NARCIS (Netherlands)

    Sharma, N.K.; Stal, L.J.; Sharma, N.K.; Rai, A.K.; Stal, L.J.

    2014-01-01

    In the current scenario, biofuels based on algae, including cyanobacteria, are expensive, complex to produce, and are only just entering the commercial phase in small quantities in pilot or demonstration plants. This chapter discusses the current scenario of using cyanobacteria for the production of

  18. Basic Substances under EU Pesticide Regulation: An Opportunity for Organic Production?

    Directory of Open Access Journals (Sweden)

    Patrice A. Marchand

    2017-02-01

    Full Text Available Some of the active substances allowed in organic production are now approved as basic sub- stances under the EU plant protection products regulation. Previously, all organic farming permitted active substances were approved as conventional plant protection products. In accordance with the criteria of Article 23 of the EU regulation (EC No 1107/2009, basic substances are granted without maximum residue limits and have a good prospect for being included in Annex II of organic farming Regulation (EC 889/2008. In fact, most of them are already permitted in organic farming. At this stage, it seems desirable to organize applications in order to avoid duplications and to clarify strategy across Europe. This organization should be planned in order to identify corresponding knowledge and data from field experiments, and to further constitute the most crucial issues related to organic production. A work of this nature was initially supported by IFOAM-EU for lecithin, calcium hydroxide and Quassia extract. The Institut Technique de l’Agriculture Biologique (ITAB was previously engaged in a large-scale approval plan motivated by the continuous demand for the regularization of compounds/substances already in use and has a mandate for testing and approving new compatible substances. Thus, the horsetail extract (Equisetum arvense was the first approved basic substance and ITAB has obtained 11 of the 15 basic substances approved at the EU level.

  19. Review: Sustainable production of hydroxymethylfurfural and levulinic acid: Challenges and opportunities

    International Nuclear Information System (INIS)

    Mukherjee, Agneev; Dumont, Marie-Josée; Raghavan, Vijaya

    2015-01-01

    Hydroxymethylfurfural (HMF) and levulinic acid (LA) are two of the most promising chemicals derived from biomass owing to their convertibility into a large number of chemicals having applications in diverse industries. Their transition from niche products to mass-produced chemicals, however, requires their production from sustainable biomass feedstocks at low costs using environment-friendly techniques. In this review, the numerous reaction systems that have been developed to produce HMF and LA from various substrates have been looked at and their merits, demerits and requirements for commercialisation outlined. Special attention has been paid to microwave irradiation-heated systems due to their dual advantages of high product yields and low environmental footprint. - Highlights: • HMF and LA are promising biorefinery platform chemicals. • Lignocellulose biomass is preferred for viable commercial-scale production. • One-pot reaction systems reduce feedstock pre-treatment and purification. • Microwave irradiation based reaction is a promising synthesis route. • HMF and LA isolation techniques need to be optimized

  20. Ecosystem services: foundations, opportunities, and challenges for the forest products sector

    Science.gov (United States)

    Trista M. Patterson; Dana L. Coelho

    2009-01-01

    The ecosystem service concept has been proposed as a meaningful framework for natural resource management. In theory, it holds concomitant benefit and consequence for the forest product sector. However, numerous barriers impede practitioners from developing concrete and enduring responses to emerging ecosystem service markets, policies, and initiatives. Principal among...

  1. Opportunities for Energy Crop Production Based on Subfield Scale Distribution of Profitability

    Directory of Open Access Journals (Sweden)

    Ian J. Bonner

    2014-10-01

    Full Text Available Incorporation of dedicated herbaceous energy crops into row crop landscapes is a promising means to supply an expanding biofuel industry while benefiting soil and water quality and increasing biodiversity. Despite these positive traits, energy crops remain largely unaccepted due to concerns over their practicality and cost of implementation. This paper presents a case study for Hardin County, Iowa, to demonstrate how subfield decision making can be used to target candidate areas for conversion to energy crop production. Estimates of variability in row crop production at a subfield level are used to model the economic performance of corn (Zea mays L. grain and the environmental impacts of corn stover collection using the Landscape Environmental Analysis Framework (LEAF. The strategy used in the case study integrates switchgrass (Panicum virgatum L. into subfield landscape positions where corn grain is modeled to return a net economic loss. Results show that switchgrass integration has the potential to increase sustainable biomass production from 48% to 99% (depending on the rigor of conservation practices applied to corn stover collection, while also improving field level profitability of corn. Candidate land area is highly sensitive to grain price (0.18 to 0.26 $·kg−1 and dependent on the acceptable subfield net loss for corn production (ranging from 0 to −1000 $·ha−1 and the ability of switchgrass production to meet or exceed this return. This work presents the case that switchgrass may be economically incorporated into row crop landscapes when management decisions are applied at a subfield scale within field areas modeled to have a negative net profit with current management practices.

  2. The Cell Factory Aspergillus Enters the Big Data Era: Opportunities and Challenges for Optimising Product Formation.

    Science.gov (United States)

    Meyer, Vera; Fiedler, Markus; Nitsche, Benjamin; King, Rudibert

    2015-01-01

    Living with limits. Getting more from less. Producing commodities and high-value products from renewable resources including waste. What is the driving force and quintessence of bioeconomy outlines the lifestyle and product portfolio of Aspergillus, a saprophytic genus, to which some of the top-performing microbial cell factories belong: Aspergillus niger, Aspergillus oryzae and Aspergillus terreus. What makes them so interesting for exploitation in biotechnology and how can they help us to address key challenges of the twenty-first century? How can these strains become trimmed for better growth on second-generation feedstocks and how can we enlarge their product portfolio by genetic and metabolic engineering to get more from less? On the other hand, what makes it so challenging to deduce biological meaning from the wealth of Aspergillus -omics data? And which hurdles hinder us to model and engineer industrial strains for higher productivity and better rheological performance under industrial cultivation conditions? In this review, we will address these issues by highlighting most recent findings from the Aspergillus research with a focus on fungal growth, physiology, morphology and product formation. Indeed, the last years brought us many surprising insights into model and industrial strains. They clearly told us that similar is not the same: there are different ways to make a hypha, there are more protein secretion routes than anticipated and there are different molecular and physical mechanisms which control polar growth and the development of hyphal networks. We will discuss new conceptual frameworks derived from these insights and the future scientific advances necessary to create value from Aspergillus Big Data.

  3. Perceived risks in product innovation projects : development of a risk skeleton

    NARCIS (Netherlands)

    Halman, J.I.M.; Keizer, J.A.; Song, X.M.

    1999-01-01

    The essence of undertaking a product innovation project is to create or establish something new. Risk taking is an intrinsic part of that process. In today's markets, with heavy competition, advanced technology and tough economic conditions, successful product innovation has become critically

  4. The Innovation Butterfly Managing Emergent Opportunities and Risks During Distributed Innovation

    CERN Document Server

    Anderson Jr , Edward G

    2012-01-01

    Product and service innovations are the result of mutually interacting creative and coordination tasks within a system that has to balance technical decisions, marketplace taste, personnel management, and stakeholder commitment. The constituent elements of such systems are often scattered across multiple firms and across the globe and constitute a complex system consisting of many interacting parts. In the spirit of the "butterfly effect", metaphorically describing the sensitivity to initials conditions of chaotic systems, this book builds an argument that "innovation butterflies" can, in the short term, take up significant amounts of effort and sap efficiencies within individual innovation projects. Such "innovation butterflies" can be prompted by external forces such as government legislation or unexpected spikes in the price of basic goods (such as oil), unexpected shifts in market tastes, or from a company manager’s decisions or those of its competitors. Even the smallest change, the smallest disruption...

  5. Combined Biogas and Bioethanol Production: Opportunities and Challenges for Industrial Application

    Directory of Open Access Journals (Sweden)

    Alessandra Cesaro

    2015-08-01

    Full Text Available In the last decades the increasing energy requirements along with the need to face the consequences of climate change have driven the search for renewable energy sources, in order to replace as much as possible the use of fossil fuels. In this context biomass has generated great interest as it can be converted into energy via several routes, including fermentation and anaerobic digestion. The former is the most common option to produce ethanol, which has been recognized as one of the leading candidates to substitute a large fraction of the liquid fuels produced from oil. As the economic competitiveness of bioethanol fermentation processes has to be enhanced in order to promote its wider implementation, the most recent trends are directed towards the use of fermentation by-products within anaerobic digestion. The integration of both fermentation and anaerobic digestion, in a biorefinery concept, would allow the production of ethanol along with that of biogas, which can be used to produce heat and electricity, thus improving the overall energy balance. This work aims at reviewing the main studies on the combination of both bioethanol and biogas production processes, in order to highlight the strength and weakness of the integrated treatment for industrial application.

  6. Certification of CCHEN's products and services under ISO 9001/2000. A major and opportune challenge

    International Nuclear Information System (INIS)

    Silva Gundelach, Carmen

    2003-01-01

    The quality revolution and the ISO 9000 standards were among the most important management tools created during the second half of the 20th century. ISO 9000 is a management standard that allows an organization to demonstrate its quality level. It is a marketing instrument used for the difficult task of maintaining and winning new markets. More importantly, it is a proven and accepted worldwide model for an organizational system to attain a world quality level and to focus on 'continuous improvement'. For this reason, CCHEN cannot remain out of this new way of working. CCHEN must generate a record of its processes within the concept of Continuous Improvement, in order to be present and considered in today's marketplace. 'Continuous improving' is defined as a permanent activity and attitude aimed at increasing the ability to respond to a client's requirements. Taking into account the impact and importance of its products and services, CCHEN decided to request certification under ISO 9001/2000 of: Personal Dosimetry Service, Irradiation in the Multipurpose Sterilization Plant for the Pharmaceutical and Cosmetics Industry, Technetium-99m and MDP Production,and Production of MTR type Fuel Elements. This certification will demonstrate the quality level and the efficacy of each one of CCHEN's processes. Working under ISO 9001/2000 will allow CCHEN to organize and systematize information related to continuous improvement and focusing on client satisfaction clients, by defining their needs and expectations with the use of a management tool and most importantly by using information, facts and optimizing resources (Au)

  7. New production processes for alpha hemihydrate open up new marketing opportunities

    International Nuclear Information System (INIS)

    Engert, W.; Lehmkaemper, O.; Bunte, H.P.

    1991-01-01

    New production processes and markets for alpha hemihydrate are discussed. Utility studies concluded that lignite gypsum is harmless in terms of public and occupational health, and is technically comparable to or superior to natural gypsum by virtue of greater purity. Semi-commercial and pilot-scale studies were carried out on the use of flue gas desulfurization (FGD) gypsum for producing alpha hemihydrate, with successful results. The process enabled pure alpha hemihydrate to be produced without dihydrate or dihydrate impurities, and of a constant, uniform quality. The treatment consists of forming pressed mouldings of FGD gypsum followed by steam autoclaving, drying and milling. Agents are used to stabilize the stackable moldings, and to act as growth inhibitors during transformation of dihydrite to alpha-hemihydrate. Markets for the product are found in mining, tunneling and road building, foundation work, floor systems, as hard plaster for dental and moulding applications, for construction industry use, and as structural and non-structural material. Details are presented of the production process and marketing concepts. 12 figs

  8. The Politics of Co-Production: Risks, Limits and Pollution

    Science.gov (United States)

    Flinders, Matthew; Wood, Matthew; Cunningham, Malaika

    2016-01-01

    Co-production is a risky method of social inquiry. It is time-consuming, ethically complex, emotionally demanding, inherently unstable, vulnerable to external shocks, subject to competing demands and it challenges many disciplinary norms. This is what makes it so fresh and innovative. And yet these research-related risks are rarely discussed and,…

  9. Allocative efficiency, employment and rice production risk: An ...

    African Journals Online (AJOL)

    Smallholder farmers have developed coping mechanisms in order to minimize the negative impact of rice production risks. A programme to accelerate the provision of education and credit is needed. The education programme should include both formal and non-formal elements. This is important for the improvement of ...

  10. Choices in recreational water quality monitoring: new opportunities and health risk trade-offs

    Science.gov (United States)

    Nevers, Meredith B.; Byappanahalli, Muruleedhara N.; Whitman, Richard L.

    2013-01-01

    With the recent release of new recreational water quality monitoring criteria, there are more options for regulatory agencies seeking to protect beachgoers from waterborne pathogens. Included are methods that can reduce analytical time, providing timelier estimates of water quality, but the application of these methods has not been examined at most beaches for expectation of health risk and management decisions. In this analysis, we explore health and monitoring outcomes expected at Lake Michigan beaches using protocols for indicator bacteria including culturable Escherichia coli (E. coli; EC), culturable enterococci (ENT), and enterococci as analyzed by qPCR (QENT). Correlations between method results were generally high, except at beaches with historically high concentrations of EC. The “beach action value” was exceeded most often when using EC or ENT as the target indicator; QENT exceeded the limit far less frequently. Measured water quality between years was varied. Although methods with equivalent health expectation have been established, the lack of relationship among method outcomes and annual changes in mean indicator bacteria concentrations complicates the decision-making process. The monitoring approach selected by beach managers may be a combination of available tools that maximizes timely health protection, cost efficiency, and collaboration among beach jurisdictions.

  11. Immunological Assays as an Opportunity of Assessment of Health Risks of Airborne Particle Mixture Including Nanoparticles

    International Nuclear Information System (INIS)

    Brzicová, Tána; Danihelka, Pavel; Micka, Vladimír; Lochman, Ivo; Lach, Karel; Lochmanová, Alexandra

    2013-01-01

    The aim of this pilot study was to evaluate perspectives of the assessment of nonspecific biological effects of airborne particulate matter including nanoparticles using appropriate immunological assays. We have selected various in vitro immunological assays to establish an array allowing us to monitor activation of the cell-mediated and humoral response of both the innate and adaptive immunity. To assess comprehensive interactions and effects, the assays were performed in whole blood cultures from healthy volunteers and we used an original airborne particle mixture from high pollution period in Ostrava region representing areas with one of the most polluted air in Europe. Even if certain effects were observed, the results of the immunological assays did not prove significant effects of airborne particles on immune cells' functions of healthy persons. However, obtained data do not exclude health risks of long-term exposure to airborne particles, especially in case of individuals with genetic predisposition to certain diseases or already existing disease. This study emphasizes the in vitro assessment of complex effects of airborne particles in conditions similar to actual ones in an organism exposed to particle mixture present in the polluted air.

  12. Ultra high risk of psychosis on committal to a young offender prison: an unrecognised opportunity for early intervention

    Directory of Open Access Journals (Sweden)

    Flynn Darran

    2012-08-01

    Full Text Available Abstract Background The ultra high risk state for psychosis has not been studied in young offender populations. Prison populations have higher rates of psychiatric morbidity and substance use disorders. Due to the age profile of young offenders one would expect to find a high prevalence of individuals with pre-psychotic or ultra-high risk mental states for psychosis (UHR. Accordingly young offender institutions offer an opportunity for early interventions which could result in improved long term mental health, social and legal outcomes. In the course of establishing a mental health in-reach service into Ireland’s only young offender prison, we sought to estimate unmet mental health needs. Methods Every third new committal to a young offenders prison was interviewed using the Comprehensive Assessment of At-Risk Mental States (CAARMS to identify the Ultra High Risk (UHR state and a structured interview for assessing drug and alcohol misuse according to DSM-IV-TR criteria, the Developmental Understanding of Drug Misuse and Dependence - Short Form (DUNDRUM-S. Results Over a twelve month period 171 young male offenders aged 16 to 20 were assessed. Of these 39 (23%, 95% confidence interval 18% to 30% met UHR criteria. UHR states peaked at 18 years, were associated with lower SOFAS scores for social and occupational function and were also associated with multiple substance misuse. The relationship with lower SOFAS scores persisted even when co-varying for multiple substance misuse. Conclusions Although psychotic symptoms are common in community samples of children and adolescents, the prevalence of the UHR state in young offenders was higher than reported for community samples. The association with impaired function also suggests that this may be part of a developing disorder. Much more attention should be paid to the relationship of UHR states to substance misuse and to the health needs of young offenders.

  13. Hazard assessment and risk management of offshore production chemicals

    International Nuclear Information System (INIS)

    Schobben, H.P.M.; Scholten, M.C.T.; Vik, E.A.; Bakke, S.

    1994-01-01

    There is a clear need for harmonization of the regulations with regard to the use and discharge of drilling and production chemicals in the North Sea. Therefore the CHARM (Chemical Hazard Assessment and Risk Management) model was developed. Both government (of several countries) and industry (E and P and chemical suppliers) participated in the project. The CHARM model is discussed and accepted by OSPARCON. The CHARM model consists of several modules. The model starts with a prescreening on the basis of hazardous properties like persistency, accumulation potential and the appearance on black lists. The core of the model.consists of modules for hazard assessment and risk analysis. Hazard assessment covers a general environmental evaluation of a chemical on the basis of intrinsic properties of that chemical. Risk analysis covers a more specific evaluation of the environmental impact from the use of a production chemical, or a combination of chemicals, under actual conditions. In the risk management module the user is guided to reduce the total risk of all chemicals used on a platform by the definition of measures in the most cost-effective way. The model calculates the environmental impact for the marine environment. Thereto three parts are distinguished: pelagic, benthic and food chain. Both hazard assessment and risk analysis are based on a proportional comparison of an estimated PEC with an estimated NEC. The PEC is estimated from the use, release, dilution and fate of the chemical and the NEC is estimated from the available toxicity data of the chemicals

  14. Identification of risk products for fragrance contact allergy

    DEFF Research Database (Denmark)

    Johansen, Jeanne Duus; Andersen, T F; Kjøller, M

    1998-01-01

    BACKGROUND: Fragrances are the first or second most common cause of contact allergy in dermatitis patients. OBJECTIVE: The aim of this study was to identify risk products for fragrance contact allergy. METHODS: The design was a case-control study with a case group of 78 fragrance-mix-positive ecz......BACKGROUND: Fragrances are the first or second most common cause of contact allergy in dermatitis patients. OBJECTIVE: The aim of this study was to identify risk products for fragrance contact allergy. METHODS: The design was a case-control study with a case group of 78 fragrance......-mix-positive eczema patients and two control groups, one consisting of 1,279 subjects selected as a random sample of the general population and the other consisting of 806 fragrance-mix-negative eczema patients. The identification of risk products was based on the patients' histories of rash to scented products....... Analysis of the associations between first-time rash caused by different specified product categories and fragrance mix sensitivity was performed using logistic regression. RESULTS: It was found that first-time rash caused by deodorant sprays and/or perfumes were related to fragrance contact allergy...

  15. Bioassays for risk assessment of coal conversion products

    Energy Technology Data Exchange (ETDEWEB)

    Schacht, S.; Sinder, C.; Pfeifer, F.; Klein, J. [DMT-Gesellschaft fuer Forschung und Pruefung mbH, Essen (Germany)

    1999-07-01

    Traditional as well as biotechnological processing coal leads to complex mixtures of products. Besides chemical and physical characterization, which provides the information for product application, there is a need for bioassays to monitor properties that are probably toxic, mutagenic or cancerogenic. Investigations carried out focused on the selection, adaptation and validation of bioassays for the sensitive estimation of toxic effects. Organisms like bacteria, Daphnia magna and Scenedesmus subspicatus, representing different complexities in the biosphere, were selected as test systems for ecotoxicological and mutagenicity studies. The results obtained indicate that bioassays are, in principle, suitable tools for characterization and evaluation of coal-derived substances and bioconversion products. Using coal products, coal-relevant model compounds and bioconversion products, data for risk assessment are presented. (orig.)

  16. Managing Bioenergy Production on Arable Field Margins for Multiple Ecosystem Services: Challenges and Opportunities

    Science.gov (United States)

    Ferrarini, Andrea; Serra, Paolo; Amaducci, Stefano; Trevisan, Marco; Puglisi, Edoardo

    2013-04-01

    Growing crops for bioenergy is increasingly viewed as conflicting with food production. However, energy use continues to rise and food production requires fuel inputs, which have increased with intensification. The debate should shift from "food or fuel" to the more challenging target: how the increasing demand for food and energy can be met in the future, particularly when water and land availability will be limited. As for food crops, also for bioenergy crops it is questioned whether it is preferable to manage cultivation to enhance ecosystem services ("land sharing" strategy) or to grow crops with lower ecosystem services but higher yield, thereby requiring less land to meet bioenergy demand ("land sparing" strategy). Energy crop production systems differ greatly in the supply of ecosystem services. The use of perennial biomass (e.g. Switchgrass, Mischantus, Giant reed) for energy production is considered a promising way to reduce net carbon emissions and mitigate climate change. In addition, regulating and supporting ecosystem services could be provided when specific management of bioenergy crops is implemented. The idea of HEDGE-BIOMASS* project is to convert the arable field margins to bioenergy crop production fostering a win-win strategy at landscape level. Main objective of the project is to improve land management to generate environmental benefits and increase farmer income. The various options available in literature for an improved field boundary management are presented. The positive/unknown/negative effects of growing perennial bioenergy crops on field margins will be discussed relatively to the following soil-related ecosystem services: (I) biodiversity conservation and enhancement, (II) soil nutrient cycling, (III) climate regulation (reduction of GHG emissions and soil carbon sequestration/stabilization, (IV) water regulation (filtering and buffering), (V) erosion regulation, (VI) pollination and pest regulation. From the analysis of available

  17. The North American opinion climate for nanotechnology and its products: Opportunities and challenges

    International Nuclear Information System (INIS)

    Priest, Susanna

    2006-01-01

    A January 2005 telephone survey of 1200 people in the U.S. and 2000 Canadians provides a snapshot of current North American opinion regarding nanotechnology at this crucial early point in its emergence from the laboratory to the arena of public discourse and public understanding. Using a typology of 'publics' developed through analysis of a previous comparative survey (Priest, S., 2006) and subsequently tested against these newer data (Priest, S., 2005) this article describes the opinion climate for nanotechnology across North America. The comparison of key results from the two countries helps illustrate how social and cultural differences contribute to reactions to new technologies, including nanotech. The article also discusses implications for nanotechnology-related public outreach and risk communication efforts

  18. Opportunities to enhance and interpret nutrient fluxes and imbalances in animal production systems by use of stable isotopes

    International Nuclear Information System (INIS)

    Jarvis, S.C.

    2002-01-01

    Full text: The flows and transfers of nutrients within agricultural systems are complex and the presence of livestock increases the complexity. Few, if any, systems are in equilibrium with respect to nutrients inputs and outputs and all are 'leaky' to some extent or other: the presence of animals inevitably increases the opportunity for inefficiency. Whilst there is still much need to enhance nutrient use in many parts of the world in order to promote crop/food production particularly in resource-poor environments, there has been considerable recent research which re- examine nutrient behaviour because of pollution effects. Understanding nutrients fluxes and budgets/balances of inputs and outputs within a system and its component parts, provides the means to assess (i) current status, (ii) extent of losses and (iii) potential options for change to reduce losses, increase nutrient use efficiency and sustain or enhance production at minimum cost. Increasingly, nutrient accounting is being used at field, farm and national scales to aid decision making and planning. To do this effectively, requires that the sources and transfers of nutrients to, from and within the system be known. The paper discusses the way in which systems and farm gate balances can be used to promote efficiency of nutrient use in relation to required production levels and to optimise (i) investment in purchased nutrients, (ii) opportunities to capitalise on internal recycling and (iii) other farming activities which influence nutrient balance, surplus and loss. A major challenge for the future will be to balance the on- and off-farm needs of supplying and utilising nutrients in order to maintain long-term sustainability of farming systems, food production and rural resources. The paper concentrates on aspects of N in livestock systems as this provides one of the main opportunities to increase effectiveness of nutrient use in agriculture throughout the world with the aim of demonstrating some of the

  19. Potential exposures and risks from beryllium-containing products.

    Science.gov (United States)

    Willis, Henry H; Florig, H Keith

    2002-10-01

    Beryllium is the strongest of the lightweight metals. Used primarily in military applications prior to the end of the Cold War, beryllium is finding new applications in many commercial products, including computers, telecommunication equipment, and consumer and automotive electronics. The use of beryllium in nondefense consumer applications is of concern because beryllium is toxic. Inhalation of beryllium dust or vapor causes a chronic lung disease in some individuals at concentrations as low as 0.01 microg/m3 in air. As beryllium enters wider commerce, it is prudent to ask what risks this might present to the general public and to workers downstream of the beryllium materials industry. We address this question by evaluating the potential for beryllium exposure from the manufacturing, use, recycle, and disposal of beryllium-containing products. Combining a market study with a qualitative exposure analysis, we determine which beryllium applications and life cycle phases have the largest exposure potential. Our analysis suggests that use and maintenance of the most common types of beryllium-containing products do not result in any obvious exposures of concern, and that maintenance activities result in greater exposures than product use. Product disposal has potential to present significant individual risks, but uncertainties concerning current and future routes of product disposal make it difficult to be definitive. Overall, additional exposure and dose-response data are needed to evaluate both the health significance of many exposure scenarios, and the adequacy of existing regulations to protect workers and the public. Although public exposures to beryllium and public awareness and concern regarding beryllium risks are currently low, beryllium risks have psychometric qualities that may lead to rapidly heightened public concern.

  20. Opportunities and challenges for the sustainable production of structurally complex diterpenoids in recombinant microbial systems.

    Science.gov (United States)

    Kemper, Katarina; Hirte, Max; Reinbold, Markus; Fuchs, Monika; Brück, Thomas

    2017-01-01

    With over 50.000 identified compounds terpenes are the largest and most structurally diverse group of natural products. They are ubiquitous in bacteria, plants, animals and fungi, conducting several biological functions such as cell wall components or defense mechanisms. Industrial applications entail among others pharmaceuticals, food additives, vitamins, fragrances, fuels and fuel additives. Central building blocks of all terpenes are the isoprenoid compounds isopentenyl diphosphate and dimethylallyl diphosphate. Bacteria like Escherichia coli harbor a native metabolic pathway for these isoprenoids that is quite amenable for genetic engineering. Together with recombinant terpene biosynthesis modules, they are very suitable hosts for heterologous production of high value terpenes. Yet, in contrast to the number of extracted and characterized terpenes, little is known about the specific biosynthetic enzymes that are involved especially in the formation of highly functionalized compounds. Novel approaches discussed in this review include metabolic engineering as well as site-directed mutagenesis to expand the natural terpene landscape. Focusing mainly on the validation of successful integration of engineered biosynthetic pathways into optimized terpene producing Escherichia coli , this review shall give an insight in recent progresses regarding manipulation of mostly diterpene synthases.

  1. Opportunities and challenges for the sustainable production of structurally complex diterpenoids in recombinant microbial systems

    Directory of Open Access Journals (Sweden)

    Katarina Kemper

    2017-05-01

    Full Text Available With over 50.000 identified compounds terpenes are the largest and most structurally diverse group of natural products. They are ubiquitous in bacteria, plants, animals and fungi, conducting several biological functions such as cell wall components or defense mechanisms. Industrial applications entail among others pharmaceuticals, food additives, vitamins, fragrances, fuels and fuel additives. Central building blocks of all terpenes are the isoprenoid compounds isopentenyl diphosphate and dimethylallyl diphosphate. Bacteria like Escherichia coli harbor a native metabolic pathway for these isoprenoids that is quite amenable for genetic engineering. Together with recombinant terpene biosynthesis modules, they are very suitable hosts for heterologous production of high value terpenes. Yet, in contrast to the number of extracted and characterized terpenes, little is known about the specific biosynthetic enzymes that are involved especially in the formation of highly functionalized compounds. Novel approaches discussed in this review include metabolic engineering as well as site-directed mutagenesis to expand the natural terpene landscape. Focusing mainly on the validation of successful integration of engineered biosynthetic pathways into optimized terpene producing Escherichia coli, this review shall give an insight in recent progresses regarding manipulation of mostly diterpene synthases.

  2. Evaluation of AECB-1119, risk of energy production

    International Nuclear Information System (INIS)

    1978-01-01

    The Inhaber report, 'Risk of Energy Production', is evaluated based on how the conclusions of the report match its objectives, the methodology used to reach the report's conclusions, and the presentation of the report. The authors recommend that a second volume containing the pertinent data used in the report should be published; and that total risks should be calculated ignoring material acquisition, construction and transportation risks, using the actual energy output of the various systems without imposing a backup energy supply, and comparing systems in such a way that death, injury and disease risks may be considered separately. They propose that the Atomic Energy Control Board should show how the report results relate to nuclear safety, and that the AECB should clarify the criteria for evaluating the small probability of a catastrophic nuclear accident. The response of the author of AECB--1119 is given in a separate section

  3. Bacterial Glycosyltransferases: Challenges and opportunities of a highly diverse enzyme class toward tailoring natural products

    Directory of Open Access Journals (Sweden)

    Jochen eSchmid

    2016-02-01

    Full Text Available The enzyme subclass of glycosyltransferases (EC 2.4 currently comprises 97 families as specified by CAZy classification. One of their important roles is in the biosynthesis of disaccharides, oligosaccharides and polysaccharides by catalyzing the transfer of sugar moieties from activated donor molecules to other sugar molecules. In addition glycosyltransferases also catalyze the transfer of sugar moieties onto aglycons, which is of great relevance for the synthesis of many high value natural products. Bacterial glycosyltransferases show a higher sequence similarity in comparison to mammalian ones. Even when most glycosyltransferases are poorly explored, state of the art technologies, such as protein engineering, domain swapping or computational analysis strongly enhance our understanding and utilization of these very promising classes of proteins. This perspective article will focus on bacterial glycosyltransferases, especially on classification, screening and engineering strategies to alter substrate specificity. The future development in these fields as well as obstacles and challenges will be highlighted and discussed.

  4. Therapeutic product disposition in at-risk populations

    International Nuclear Information System (INIS)

    Foster, B. C.

    2009-01-01

    In an emergency situation, such as a chemical, biological, radionuclide, nuclear or explosion (CBRNE) event, all patient populations are at increased risk of serious adverse events. Therapeutic product (TP) safety and efficacy depend on the disposition of the product through absorption, distribution, metabolism and excretion. The ability of a patient to benefit from or merely tolerate a TP can be modified by many factors, including but not limited to culture, diet, disease, environmental contaminants, genetic predisposition, stress and socioeconomic status and recent life experiences. Metabolism is considered to have the greatest effect on safety and efficacy, as chemicals not metabolised can accumulate to toxic levels. Inter-individual variances in most drug metabolism enzymes may range up to greater than 1000-fold. The fetus, neonates, infants, individuals with hormonal change, infection or prior exposure to licit or illicit products and the elderly are more susceptible to increased risk of serious adverse health effects. The critically ill are the most at risk. The at-risk populations for a serious adverse event are dependent then on the CBRNE event, their physical and cognitive states and the inter-individual intrinsic and extrinsic factors that affect TP disposition. (authors)

  5. Tail production and removal. Risk, challenges and possibilities

    International Nuclear Information System (INIS)

    Magelssen, Hans Chr.

    1997-01-01

    Elf is one of the companies with the longest experience as an oil operator in Norway. This presentation discusses experiences made by Elf on tail production and removal. It starts with a description of risk, economic analyses and individual cash flow discounting and then deals with the challenges and possibilities of extended use of existing installations. Elf does not use individual cash flow discounting, which has several disadvantages, but rather traditional indicators like NPV (Net Present Value), IRR (Internal Rate of Return), payback time and balance price calculated by means of cash flow, as well as a type of ROI (Return On Investment). In normal present value calculation, the decision-maker estimates the total risk for the project and compare this with a relevant present value. Another method is proposed if it is desirable to include risk directly in calculating the present value. In this method the present value is shown as a probability distribution. A probability curve is associated with the most important variables. Some of Elf's experience with tail production and removal policy is described. The tail production from a gas field is a great challenge for the operator of the field, but the other actors should also be concerned with this part of a field's lifetime. So far there is no absolute requirement that large platforms must be removed. The presentations end with some discussion about economy and production policies for the final years of a field. 3 figs

  6. Quality management system in CCHEN and their product/service certification under ISO 9001:2000; pertinence and opportunity

    International Nuclear Information System (INIS)

    Silva Gundelach, Carmen

    2002-01-01

    This paper describes the pertinence and opportunity for having some strategic products and services of CCHEN in a Quality Management System under ISO 9001:2000. The advantages for the personnel, clients and for the continual improvement are showned in this document. In order to increase our products and services and to enhance their competitive level, it is necessary to have a very good planned process. In a competitive and global world is the quality an attribute that has to be recognized by our clients; today it is not sufficient to know that we are working good, it is necessary to show we are doing thinks well and our clients have to recognize this: customer satisfaction. The implementation of the ISO 9000 family has the significance of a rational quality management system far from inefficient burocracy that increases the credibility of our products and services and that developes and increases the autodiscipline inside the organization and enhances the continual improvement. The starting of this process was a strategic decission that necessarily is going to move our organization to the Changes (author)

  7. Automated systems to identify relevant documents in product risk management

    Science.gov (United States)

    2012-01-01

    Background Product risk management involves critical assessment of the risks and benefits of health products circulating in the market. One of the important sources of safety information is the primary literature, especially for newer products which regulatory authorities have relatively little experience with. Although the primary literature provides vast and diverse information, only a small proportion of which is useful for product risk assessment work. Hence, the aim of this study is to explore the possibility of using text mining to automate the identification of useful articles, which will reduce the time taken for literature search and hence improving work efficiency. In this study, term-frequency inverse document-frequency values were computed for predictors extracted from the titles and abstracts of articles related to three tumour necrosis factors-alpha blockers. A general automated system was developed using only general predictors and was tested for its generalizability using articles related to four other drug classes. Several specific automated systems were developed using both general and specific predictors and training sets of different sizes in order to determine the minimum number of articles required for developing such systems. Results The general automated system had an area under the curve value of 0.731 and was able to rank 34.6% and 46.2% of the total number of 'useful' articles among the first 10% and 20% of the articles presented to the evaluators when tested on the generalizability set. However, its use may be limited by the subjective definition of useful articles. For the specific automated system, it was found that only 20 articles were required to develop a specific automated system with a prediction performance (AUC 0.748) that was better than that of general automated system. Conclusions Specific automated systems can be developed rapidly and avoid problems caused by subjective definition of useful articles. Thus the efficiency of

  8. Household anaerobic digester for bioenergy production in developing countries: opportunities and challenges.

    Science.gov (United States)

    Surendra, K C; Takara, Devin; Jasinski, Jonas; Khanal, Samir Kumar

    2013-01-01

    Access to clean and affordable energy is vital for advancing development objectives, particularly in rural areas of developing countries. There are some three billion people in these regions, however, who lack consistent access to energy and rely on traditional solid fuels such as firewood, cattle manure, and crop residues for meeting cooking and heating needs. Excessive use of such highly polluting resources creates serious environmental, social and public health issues. In this context, household digesters (which convert readily available feedstocks such as cattle manure, human excreta, and crop residues into biogas) have the potential to play a significant role in supplying methane as a clean, renewable energy resource for remote geographies. In addition to bioenergy production, the slurry generated from anaerobic digestion is rich in nutrients and can improve the physical, chemical, and biological attributes of soil when applied to agricultural land. This type of approach has the potential to significantly reduce greenhouse gas emissions while simultaneously improving the quality of life. Despite a long history of research and innovation for the development and optimization of household digesters, little is known and has been reported for the application of these systems in decentralized communities. The primary purpose of this paper seeks to review the dearth of literature pertaining to small-scale anaerobic digesters in remote geographies and in regions where much of the world's population reside.

  9. Evaluation of Life-Cycle Assessment Studies of Chinese Cement Production: Challenges and Opportunities

    Energy Technology Data Exchange (ETDEWEB)

    Lu, Hongyou; Masanet, Eric; Price, Lynn

    2009-05-29

    The use of life-cycle assessment (LCA) to understand the embodied energy, environmental impacts, and potential energy-savings of manufactured products has become more widespread among researchers in recent years. This paper reviews recent LCA studies in the cement industry in China and in other countries and provides an assessment of the methodology used by the researchers compared to ISO LCA standards (ISO 14040:2006, ISO 14044:2006, and ISO/TR 14048:2002). We evaluate whether the authors provide information on the intended application, targeted audience, functional unit, system boundary, data sources, data quality assessment, data disaggregation and other elements, and draw conclusions regarding the level of adherence to ISO standards for the papers reviewed. We found that China researchers have gained much experience during last decade, but still have room for improvement in establishing boundaries, assessing data quality, identifying data sources, and explaining limitations. The paper concludes with a discussion of directions for future LCA research in China.

  10. Algorithm of actions to identify and reduce risks in the production of milk and plant products

    Directory of Open Access Journals (Sweden)

    L. E. Glagoleva

    2016-01-01

    Full Text Available Foods with a new generation of functional and improved consumer properties, corresponds to the modern concepts of nutrition science and consumer needs. functional food production is a major global trend in food science and the subject of innovation. One of the important trends is the use of plant complexes and plant food systems. Using the plant complexes (PC and plant food systems (PFS provides a number of benefits: improved consumer properties of the product, do not need to change the process, it is possible to control directional rheological properties and consistency of the finished products, reduced the number of risk points in the production cycle. This paper describes the development of an algorithm of action to identify and mitigate risks in the production of milk and plant products. Also conducted a risk analysis, identified and assessed the risks in the process of production, installed capacity of available resources to reduce the level of risk. Established and submitted to the critical control points in production processes, as well as the critical limits for each critical control points, and the procedure for corrective action in case of violations of the past. During the study, measured changes in the quantitative and qualitative composition of microflora of semi-finished and Quantity of Mesophilic Aerobic and Facultative Anaerobic Microorganisms (QMAFAnM. To determine QMAFAnM samples were taken: 1 – cheesecakes (control, 2 – cheesecakes with RPS. Microbiological studies analyzed frozen-conjugated semi-finished products was determined within 90 days. It is clear from the data that the cottage cheese with semi-finished products have a lower RPM 11.7%. Analyzing the data, it is possible to conclude that the physico-chemical, organoleptic and microbiological indicators of products was developed to set standards on cheese semi-finished products. multilevel structure that characterizes the quality indicators has been developed and is

  11. Challenges and opportunities of the bio-pesticides production by solid-state fermentation: filamentous fungi as a model.

    Science.gov (United States)

    De la Cruz Quiroz, Reynaldo; Roussos, Sevastianos; Hernández, Daniel; Rodríguez, Raúl; Castillo, Francisco; Aguilar, Cristóbal N

    2015-01-01

    In recent years, production and use of bio-pesticides have increasing and replacing some synthetic chemical pesticides applied to food commodities. In this review, biological control is focused as an alternative, to some synthetic chemical treatments that cause environmental, human health, and food quality risks. In addition, several phytopathogenic microorganisms have developed resistance to some of these synthetic chemicals and become more difficult to control. Worldwide, the bio-pesticides market is growing annually at a rate of 44% in North America, 20% in Europe and Oceania, 10% in Latin and South American countries and 6% in Asia. Use of agro-industrial wastes and solid-state fermentation (SSF) technology offers an alternative to bio-pesticide production with advantages versus conventional submerged fermentations, as reduced cost and energy consumption, low production of residual water and high stability products. In this review, recent data about state of art regarding bio-pesticides production under SSF on agroindustrial wastes will be discussed. SSF can be defined as a microbial process that generally occurs on solid material in the absence of free water. This material has the ability to absorb water with or without soluble nutrients, since the substrate must have water to support the microorganism's growth and metabolism. Changes in water content are analyzed in order to select the conditions for a future process, where water stress can be combined with the best spore production conditions, obtaining in this way an inexpensive biotechnological option for modern agriculture in developing countries.

  12. Probabilistic framework for product design optimization and risk management

    Science.gov (United States)

    Keski-Rahkonen, J. K.

    2018-05-01

    Probabilistic methods have gradually gained ground within engineering practices but currently it is still the industry standard to use deterministic safety margin approaches to dimensioning components and qualitative methods to manage product risks. These methods are suitable for baseline design work but quantitative risk management and product reliability optimization require more advanced predictive approaches. Ample research has been published on how to predict failure probabilities for mechanical components and furthermore to optimize reliability through life cycle cost analysis. This paper reviews the literature for existing methods and tries to harness their best features and simplify the process to be applicable in practical engineering work. Recommended process applies Monte Carlo method on top of load-resistance models to estimate failure probabilities. Furthermore, it adds on existing literature by introducing a practical framework to use probabilistic models in quantitative risk management and product life cycle costs optimization. The main focus is on mechanical failure modes due to the well-developed methods used to predict these types of failures. However, the same framework can be applied on any type of failure mode as long as predictive models can be developed.

  13. Responses to climate and economic risks and opportunities across national and ecological boundaries: changing household strategies on the Mongolian plateau

    International Nuclear Information System (INIS)

    Brown, Daniel G; Agrawal, Arun; Wang, Jun; Sass, Daniel A; Hua, Jin; Xie, Yichun

    2013-01-01

    Climate changes on the Mongolian Plateau are creating new challenges for the households and communities of the region. Much of the existing research on household choices in response to climate variability and change focuses on environmental risks and stresses. In contrast, our analysis highlights the importance of taking into account environmental and economic opportunities in explaining household adaptation choices. We surveyed over 750 households arrayed along an ecological gradient and matched across the national border in Mongolia and the Inner Mongolia Autonomous Region, China, asking what changes in livelihoods strategies households made over the last ten years, and analyzed these choices in two broad categories of options: diversification and livestock management. We combined these data with remotely sensed information about vegetation growth and self-reported exposure to price fluctuations. Our statistical results showed that households experiencing lower ecological and economic variability, higher average levels of vegetation growth, and with greater levels of material wealth, were often those that undertook more actions to improve their conditions in the face of variability. The findings have implications both for how interventions aimed at supporting ongoing choices might be targeted and for theory construction related to social adaptation. (letter)

  14. Sustainable production program in the Mexican mining industry: occupational risks

    Directory of Open Access Journals (Sweden)

    Andrea Zavala Reyna

    2015-07-01

    Full Text Available Speaking of mining and sustainability sounds contradictory, as the environmental impact generated by resource extraction is well known. However, there are mining companies that are working to be safe and environmentally friendly. An example of this is presented in this study aimed at identifying occupational risks generated by the activities of a small-scale gold and silver mine located in northwestern Mexico. The methodology followed was a Sustainable Production Program (SPP based on a continuous cycle of five steps in which the tools of cleaner production and pollution prevention are adapted. As a result of this project, it was possible to implement SPP activities: training for workers, use of personal protective equipment and adequate handling of chemicals. As a conclusion, it was verified that SPP application helped this mining company move towards sustainable patterns of production.

  15. Foreign direct investment in South Africa: how big is Southern Africa’s natural product opportunity and what trade issues impede sectoral development?

    OpenAIRE

    Bennett, Ben

    2006-01-01

    This study was conducted to identify the scale of the trade opportunity for natural product exports from Southern Africa and to recommend actions to address market access issues constraining sectoral growth.\\ud Field research was undertaken in Malawi, Zimbabwe, Namibia, South Africa and the United Kingdom between 9th January and 25th February 2006. The study concentrated on ten countries in Southern Africa1 with potential to export significant quantities of natural products. These products ar...

  16. Break-even price for upstream activities in Brazil: Evaluation of the opportunity cost of oil production delay in a non-mature sedimentary production region

    International Nuclear Information System (INIS)

    Szklo, Alexandre Salem; Machado, Giovani; Carneiro, Jason Thomas Guerreiro

    2008-01-01

    Some Latin American policy-makers and analysts state that it would be better to hold oil reserves in place than to produce and cash it now, given the recent oil prices spikes and the fear related to future oil supply disruptions. This article evaluates the strategy of delaying the start-up of oil production in a discovered field with proved reserves. A Reference Discounted Cash Flow (FCD-R) for a typical 350 million barrel Brazilian oil field was simulated. The study estimated which future oil price may render the project insensitive to a delay of 5, 10, 15 or 20 years in its production beginning. Additionally, the value of the in situ oil stock was calculated, providing the opportunity cost for delaying oil production in a frontier area, such as Brazil. It is an application of the Hotelling Principle. Findings indicate that progressive delays of 5 years in the start-up of operation of a typical oil field reduce its revenues by a factor of 2. A delay of 10 years would be justifiable at international oil prices higher than US $15/bbl. Delays higher than 10 years lead this break-even price to values between US $200 and 350/bbl. (author)

  17. Risk assessment of allergen metals in cosmetic products.

    Science.gov (United States)

    Sipahi, Hande; Charehsaz, Mohammad; Güngör, Zerrin; Erdem, Onur; Soykut, Buğra; Akay, Cemal; Aydin, Ahmet

    2015-01-01

    Cosmetics are one of the most common reasons for hospital referrals with allergic contact dermatitis. Because of the increased use of cosmetics within the population and an increase in allergy cases, monitoring of heavy metals, especially allergen metals, is crucial. The aim of this study was to investigate the concentration of allergen metals, nickel (Ni), cobalt (Co), and chromium (Cr), in the most commonly used cosmetic products including mascara, eyeliner, eye shadow, lipstick, and nail polish. In addition, for safety assessment of cosmetic products, margin of safety of the metals was evaluated. Forty-eight makeup products were purchased randomly from local markets and large cosmetic stores in Istanbul, Turkey, and an atomic absorption spectrometer was used for metal content determination. Risk assessment of the investigated cosmetic products was performed by calculating the systemic exposure dosage (SED) using Scientific Committee on Consumer Safety guideline. According to the results of this investigation in all the samples tested, at least two of the allergen metals, Ni and/or Co and/or Cr were detected. Moreover, 97% of the Ni-detected products, 96% of Cr- and 54% of Co-detected products, contained over 1 μg/g of this metals, which is the suggested ultimate target value for sensitive population and thereby can be considered as the possible allergen. On the basis of the results of this study, SED of the metals was negligible; however, contact dermatitis caused by cosmetics is most probably due to the allergen metal content of the products. In conclusion, to assess the safety of the finished products, postmarketing vigilance and routine monitoring of allergen metals are very important to protect public health.

  18. Graphene toxicity as a double-edged sword of risks and exploitable opportunities: a critical analysis of the most recent trends and developments

    Science.gov (United States)

    Volkov, Yuri; McIntyre, Jennifer; Prina-Mello, Adriele

    2017-06-01

    Increased production volumes and a broadening application spectrum of graphene have raised concerns about its potential adverse effects on human health. Numerous reports demonstrate that graphene irrespective of its particular form exerts its effects on a widest range of living organisms, including prokaryotic bacteria and viruses, plants, micro- and macro-invertebrates, mammalian and human cells and whole animals in vivo. However, the available experimental data is frequently a matter of significant divergence and even controversy. Therefore, we provide here a critical analysis of the most recent (2015-2016) reports accumulated in the graphene-related materials biocompatibility and toxicology field in order to elucidate the cutting edge achievements, emerging trends and future opportunities in the area. Experimental findings from the diverse in vitro and in vivo model systems are analysed in the context of the most likely graphene exposure scenarios, such as respiratory inhalation, ingestion route, parenteral administration and topical exposure through the skin. Key factors influencing the toxicity of graphene and its complex derivatives as well as potential risk mitigation approaches exploiting graphene physicochemical properties, surface modifications and possible degradation pathways are also discussed along with its emerging applications for healthcare, diagnostics and innovative therapeutic approaches.

  19. Occupational musculoskeletal and mental health: Significance of rationalization and opportunities to create sustainable production systems - A systematic review.

    Science.gov (United States)

    Westgaard, R H; Winkel, J

    2011-01-01

    This literature review aims to identify occupational musculoskeletal and mental health effects of production system rationalization as well as organizational-level measures that may improve health outcome ("modifiers" in this review). A short review of the effect of ergonomic interventions is included as background and rationalization is discussed as a theoretical concept. Indicator variables for occupational musculoskeletal and mental health and related risk factors are presented. Variables with a generalized format were allowed in the literature searches (e.g., job satisfaction and absenteeism were accepted as risk factor and health indicator, respectively), suitable for the research fields of work sociology, organization science, human resource management (HRM) and economics research. One hundred and sixty-two studies of rationalization effects on health and risk factors and 72 organization-level modifier results were accepted into the final database. Entries were sorted by rationalization strategy and work life sector, and trends in outcome (positive, mixed, no effect, or negative effect on health and risk factors) were determined. Rationalizations have a dominant negative effect on health and risk factors (57% negative, 19% positive); the most negative effects were found for downsizing and restructuring rationalizations in general (71 studies negative, 13 positive) and for the health care sector in particular (36 studies negative, 2 positive). The rationalization strategy High Performance Work System (HPWS) was associated with the highest fraction positive outcome studies (6 of 10 studies). Other rationalization strategies (lean practices, parallel vs. serial production and mechanization level) reported intermediate results, in part dependent on work life sector, but also on the year when studies were carried out. Worker participation, resonant management style, information, support, group autonomy and procedural justice were modifiers with favourable

  20. Challenges and Opportunities While Developing a Group A Meningococcal Conjugate Vaccine Within a Product Development Partnership: A Manufacturer's Perspective From the Serum Institute of India

    Science.gov (United States)

    Kulkarni, Prasad S.; Socquet, Muriel; Jadhav, Suresh S.; Kapre, Subhash V.; LaForce, F. Marc; Poonawalla, Cyrus S.

    2015-01-01

    Background. In 2002, the Meningitis Vaccine Project (MVP) chose the Serum Institute of India, Ltd (SIIL), as its manufacturing partner to establish a product development partnership (PDP) with the Meningitis Vaccine Project (MVP). MVP was a collaboration between PATH and the World Health Organization (WHO) to develop meningococcal conjugate vaccines for sub-Saharan Africa. Method. From the outset, SIIL recognized that a partnership with MVP carried some risk but also offered important opportunities for accessing new conjugate vaccine technology and know-how. Over 3 years, SIIL successfully accepted technology transfer for the group A meningococcal polysaccharide from SynCo Bio Partners and a conjugation method from the US Food and Drug Administration. Results. SIIL successfully scaled up production of a group A meningococcal conjugate vaccine that used SIIL tetanus toxoid as the carrier protein. Phase 1 studies began in India in 2005, followed by phase 2/3 studies in Africa and India. A regulatory dossier was submitted to the Indian authorities in April 2009 and WHO in September 2009. Export license was granted in December 2009, and WHO prequalification was obtained in June 2010. Vaccine was introduced at public scale in Burkina Faso that December. The group A meningococcal conjugate vaccine was named MenAfriVac, and is the first internationally qualified vaccine developed outside of big pharma. Conclusions. The project proved to be a sound investment for SIIL and is a concrete example of the potential for PDPs to provide needed products for resource-poor countries. PMID:26553678

  1. The Hip Hop peer crowd: An opportunity for intervention to reduce tobacco use among at-risk youth.

    Science.gov (United States)

    Walker, Matthew W; Navarro, Mario A; Hoffman, Leah; Wagner, Dana E; Stalgaitis, Carolyn A; Jordan, Jeffrey W

    2018-07-01

    Peer crowds, peer groups with macro-level connections and shared norms that transcend geography and race/ethnicity, have been linked to risky health behaviors. Research has demonstrated that Hip Hop peer crowd identification, which is common among multicultural youth, is associated with increased risk of tobacco use. To address this, the FDA Center for Tobacco Products created Fresh Empire, the first national tobacco education campaign tailored for Hip Hop youth aged 12-17 who are multicultural (Hispanic, African American, Asian-Pacific Islander, or Multiracial). As part of campaign development, peer crowd (Hip Hop, Mainstream, Popular, Alternative, Country) and cigarette smoking status were examined for the first time with a nationally recruited sample. Youth were recruited via targeted social media advertisements. Participants aged 13-17 (n = 5153) self-reported peer crowd identification via the I-Base Survey™ and cigarette smoking status. Differences in smoking status by peer crowd were examined using chi-square and followed up with z-tests to identify specific differences. Alternative youth were most at risk of cigarette smoking, followed by Hip Hop. Specifically, Hip Hop youth were significantly less likely to be Non-susceptible Non-triers than Popular, Mainstream, and Country youth, and more likely to be Experimenters than Popular and Mainstream youth. Representative studies show that Alternative is relatively small compared to other high-risk crowds, such as the Hip Hop peer crowd. The current research underscores the potential utility of interventions tailored to larger at-risk crowds for campaigns like Fresh Empire. Published by Elsevier Ltd.

  2. Risk management and lessons learned solutions for satellite product assurance

    Science.gov (United States)

    Larrère, Jean-Luc

    2004-08-01

    The historic trend of the space industry towards lower cost programmes and more generally a better economic efficiency raises a difficult question to the quality assurance community: how to achieve the same—or better—mission success rate while drastically reducing the cost of programmes, hence the cost and level of quality assurance activities. EADS Astrium Earth Observation and Science (France) Business Unit have experimented Risk Management and Lessons Learned on their satellite programmes to achieve this goal. Risk analysis and management are deployed from the programme proposal phase through the development and operations phases. Results of the analysis and the corresponding risk mitigation actions are used to tailor the product assurance programme and activities. Lessons learned have been deployed as a systematic process to collect positive and negative experience from past and on-going programmes and feed them into new programmes. Monitoring and justification of their implementation in programmes is done under supervision from the BU quality assurance function. Control of the system is ensured by the company internal review system. Deployment of these methods has shown that the quality assurance function becomes more integrated in the programme team and development process and that its tasks gain focus and efficiency while minimising the risks associated with new space programmes.

  3. Dietary Advanced Glycation End Products and Cardiometabolic Risk.

    Science.gov (United States)

    Luévano-Contreras, Claudia; Gómez-Ojeda, Armando; Macías-Cervantes, Maciste Habacuc; Garay-Sevilla, Ma Eugenia

    2017-08-01

    This report analyzes emerging evidence about the role of dietary advanced glycation end products (AGEs) as a cardiometabolic risk factor. Two important aspects are discussed: First, the modulation of AGE load by dietary AGEs; second, if the evidence of clinical and observational studies is enough to make dietary recommendations towards lowering AGE intake. Clinical studies in subjects with diabetes mellitus have shown that high intake of dietary AGEs increases inflammation markers, oxidative stress, and could impair endothelial function. In subjects at risk for cardiometabolic diseases (with overweight, obesity, or prediabetes), dietary AGE restriction decreases some inflammatory molecules and improves insulin sensitivity. However, studies in healthy subjects are limited, and not all of the studies have shown a decrease in circulating AGEs. Therefore, it is still unclear if dietary AGEs represent a health concern for people potentially at risk for cardiometabolic diseases. The evidence shows that dietary AGEs are bioavailable and absorbed, and the rate of excretion depends on dietary intake. The metabolic fate of most dietary AGEs remains unknown. Regardless, most studies have shown that by diminishing AGE intake, circulating levels will also decrease. Thus, dietary AGEs can modulate the AGE load at least in patients with DM, overweight, or obesity. Studies with specific clinical outcomes and large-scale observational studies are needed for a better risk assessment of dietary AGEs and to establish dietary recommendations accordingly.

  4. Inter-organizational Collaboration: Product, Knowledge and Risk

    Directory of Open Access Journals (Sweden)

    Norbert Jastroch

    2011-10-01

    Full Text Available Inter-organizational collaboration is no longer entirely a free choice, but is close to a necessity imposed by economic, technical, and knowledge-related concerns. A deep understanding of collaboration will assist in making intelligent decisions on entering, operating, and evaluating collaborative ventures. The nature of the partners—industrial corporations, consultants, academic institutions and others—and the collaborative structure are important, but so too is the nature of the product. We consider its effects in the collaborative domain on knowledge, intellectual property, and catastrophic risk.

  5. Bacillus cereus in personal care products: risk to consumers.

    Science.gov (United States)

    Pitt, T L; McClure, J; Parker, M D; Amézquita, A; McClure, P J

    2015-04-01

    Bacillus cereus is ubiquitous in nature and thus occurs naturally in a wide range of raw materials and foodstuffs. B. cereus spores are resistant to desiccation and heat and able to survive dry storage and cooking. Vegetative cells produce several toxins which on ingestion in sufficient numbers can cause vomiting and/or diarrhoea depending on the toxins produced. Gastrointestinal disease is commonly associated with reheated or inadequately cooked foods. In addition to being a rare cause of several acute infections (e.g. pneumonia and septicaemia), B. cereus can also cause localized infection of post-surgical or trauma wounds and is a rare but significant pathogen of the eye where it may result in severe endophthalmitis often leading to loss of vision. Key risk factors in such cases are trauma to the eye and retained contaminated intraocular foreign bodies. In addition, rare cases of B. cereus-associated keratitis (inflammation of the cornea) have been linked to contact lens use. Bacillus cereus is therefore a microbial contaminant that could adversely affect product safety of cosmetic and facial toiletries and pose a threat to the user if other key risk factors are also present. The infective dose in the human eye is unknown, but as few as 100 cfu has been reported to initiate infection in a susceptible animal model. However, we are not aware of any reports in the literature of B. cereus infections in any body site linked with use of personal care products. Low levels of B. cereus spores may on occasion be present in near-eye cosmetics, and these products have been used by consumers for many years. In addition, exposure to B. cereus is more likely to occur through other routes (e.g. dustborne contamination) due to its ubiquity and resistance properties of spores. The organism has been recovered from the eyes of healthy individuals. Therefore, although there may be a perceived hazard, the risk of severe eye infections as a consequence of exposure through

  6. Biological risks associated with consumption of reptile products

    DEFF Research Database (Denmark)

    Magnino, S.; Colin, P.; Dei-Cas, E.

    2009-01-01

    recently increased in some areas of the world. Biological risks associated with the consumption of products from both farmed and wild reptile meat and eggs include infections caused by bacteria (Salmonella spp., Vibrio spp.). parasites (Spirometra, Trichinella, Gnathostoma, pentastomids), as well...... to increase the occurrence of biological hazards in reptile meat. Application of GHP, GMP and HACCP procedures, respectively at farm and slaughterhouse level, is crucial for controlling the hazards.......The consumption of a wide variety of species of reptiles caught from the wild has been an important source of protein for humans world-wide for millennia. Terrapins. snakes, lizards, crocodiles and iguanas are now farmed and the consumption and trade of their meat and other edible products have...

  7. LISTERIA MONOCYTOGENES RISK EVALUATION IN READY TO EAT DELI PRODUCTS

    Directory of Open Access Journals (Sweden)

    T Civera

    2013-02-01

    Full Text Available Listeria monocytogenes has become one of the major concerns for food safety. Its ability to survive and replicate at low temperature, pH and high salt concentration, makes the bacterium a threat, mostly for RTE products. For these reasons, the present research was aimed at detecting the ability of growth of L. monocytogenes in RTE products retrieved from one deli store. Samples were analysed for L. monocytogenes detection, then inoculated with the pathogen (105cell/ml and stored at refrigeration temperature for the duration of their shelf-life (15-60 days. In all the products L. monocytogenes was not detected before experimental contamination. The challenge test evidenced that experimentally inoculated L. monocytogenes was not able to multiply for the duration of the entire shelf-life. These results indicated that the tested products could be considered as foods which are not able to support the growth of L. monocytogenes, as indicated by E.C. Regulation 2073/05. However, in order to guarantee consumer’s safety, it needs to be emphasized the need of a correct application of the GMPs, required for lowering the risk of initial contamination.

  8. Peaking of world oil production: Impacts, mitigation, & risk management

    Energy Technology Data Exchange (ETDEWEB)

    Hirsch, R.L. (SAIC); Bezdek, Roger (MISI); Wendling, Robert (MISI)

    2005-02-01

    The peaking of world oil production presents the U.S. and the world with an unprecedented risk management problem. As peaking is approached, liquid fuel prices and price volatility will increase dramatically, and, without timely mitigation, the economic, social, and political costs will be unprecedented. Viable mitigation options exist on both the supply and demand sides, but to have substantial impact, they must be initiated more than a decade in advance of peaking.... The purpose of this analysis was to identify the critical issues surrounding the occurrence and mitigation of world oil production peaking. We simplified many of the complexities in an effort to provide a transparent analysis. Nevertheless, our study is neither simple nor brief. We recognize that when oil prices escalate dramatically, there will be demand and economic impacts that will alter our simplified assumptions. Consideration of those feedbacks will be a daunting task but one that should be undertaken. Our aim in this study is to-- • Summarize the difficulties of oil production forecasting; • Identify the fundamentals that show why world oil production peaking is such a unique challenge; • Show why mitigation will take a decade or more of intense effort; • Examine the potential economic effects of oil peaking; • Describe what might be accomplished under three example mitigation scenarios. • Stimulate serious discussion of the problem, suggest more definitive studies, and engender interest in timely action to mitigate its impacts.

  9. Safety and risk assessment of ceramide 3 in cosmetic products.

    Science.gov (United States)

    Choi, Seul Min; Lee, Byung-Mu

    2015-10-01

    Ceramide 3 is used mainly as a moisturizer in various cosmetic products. Although several safety studies on formulations containing pseudo-ceramide or ceramide have been conducted at the preclinical and clinical levels for regulatory approval, no studies have evaluated the systemic toxicity of ceramide 3. To address this issue, we conducted a risk assessment and comprehensive toxicological review of ceramide and pseudo-ceramide. We assumed that ceramide 3 is present in various personal and cosmetic products at concentrations of 0.5-10%. Based on previously reported exposure data, the margin of safety (MOS) was calculated for product type, use pattern, and ceramide 3 concentration. Lipsticks with up to 10% ceramide 3 (MOS = 4111) are considered safe, while shampoos containing 0.5% ceramide 3 (MOS = 148) are known to be safe. Reported MOS values for body lotion applied to the hands (1% ceramide 3) and back (5% ceramide 3) were 103 and 168, respectively. We anticipate that face cream would be safe up to a ceramide 3 concentration of 3% (MOS = 149). Collectively, the MOS approach indicated no safety concerns for cosmetic products containing less than 1% ceramide 3. Copyright © 2015 Elsevier Ltd. All rights reserved.

  10. Financial disclosure and toxic products: encouraging wall street to anticipate product risk and exercise precaution.

    Science.gov (United States)

    Lewis, Sanford; Byrne, Margaret

    2009-01-01

    Amidst discussion by policymakers about how regulators' failure to ensure disclosure of risks contributed to the current financial crisis, we assess how emerging product toxicity risks are addressed in companies' financial reports. Will corporations blindside investors with "the next asbestos?" Existing disclosures are found lacking in the specificity needed to forewarn of liabilities and reputational damage from the use of potentially harmful materials-from nanotechnologies, to asthmagens, to perfluorinated compounds. Improved standards could protect investors while also enhancing corporate incentives to use safer materials. Reforms by the Securities and Exchange Commission and the Financial Accounting Standards Board are recommended.

  11. Biological risks associated with consumption of reptile products.

    Science.gov (United States)

    Magnino, Simone; Colin, Pierre; Dei-Cas, Eduardo; Madsen, Mogens; McLauchlin, Jim; Nöckler, Karsten; Maradona, Miguel Prieto; Tsigarida, Eirini; Vanopdenbosch, Emmanuel; Van Peteghem, Carlos

    2009-09-15

    The consumption of a wide variety of species of reptiles caught from the wild has been an important source of protein for humans world-wide for millennia. Terrapins, snakes, lizards, crocodiles and iguanas are now farmed and the consumption and trade of their meat and other edible products have recently increased in some areas of the world. Biological risks associated with the consumption of products from both farmed and wild reptile meat and eggs include infections caused by bacteria (Salmonella spp., Vibrio spp.), parasites (Spirometra, Trichinella, Gnathostoma, pentastomids), as well as intoxications by biotoxins. For crocodiles, Salmonella spp. constitute a significant public health risk due to the high intestinal carrier rate which is reflected in an equally high contamination rate in their fresh and frozen meat. There is a lack of information about the presence of Salmonella spp. in meat from other edible reptilians, though captive reptiles used as pets (lizards or turtles) are frequently carriers of these bacteria in Europe. Parasitic protozoa in reptiles represent a negligible risk for public health compared to parasitic metazoans, of which trichinellosis, pentastomiasis, gnathostomiasis and sparganosis can be acquired through consumption of contaminated crocodile, monitor lizard, turtle and snake meat, respectively. Other reptiles, although found to harbour the above parasites, have not been implicated with their transmission to humans. Freezing treatment inactivates Spirometra and Trichinella in crocodile meat, while the effectiveness of freezing of other reptilian meat is unknown. Biotoxins that accumulate in the flesh of sea turtles may cause chelonitoxism, a type of food poisoning with a high mortality rate in humans. Infections by fungi, including yeasts, and viruses widely occur in reptiles but have not been linked to a human health risk through the contamination of their meat. Currently there are no indications that natural transmissible spongiform

  12. Risks arising during manipulation with radiologically specific products of biotechnical production

    International Nuclear Information System (INIS)

    Mitrovic, R.; Vukovic, D.; Vicentijevic, M.; Kljajic, R.

    1998-01-01

    Objective of this study was to review the risk of exposure to radiocaesium (134+137Cs), which biologically presents the most toxic radionuclide, of people engaged in the process of supervision, transport and storage of the radiologically specific products, like concentrated protein feedstuff (fish meal, powdered milk), wool, cow hide and chamois. The discussion is based on the results of a radiological-hygienic analysis of these products in the context of veterinary-sanitary control, performed in the authorized referent Laboratory for Radiation Hygiene (LABRAH) at the Scientific Institute for Veterinary Medicine of Serbia in Belgrade (Yugoslavia)

  13. 75 FR 391 - Medical Device Quality System Regulation Educational Forum on Risk Management Through the Product...

    Science.gov (United States)

    2010-01-05

    ...] Medical Device Quality System Regulation Educational Forum on Risk Management Through the Product Life... on Risk Management through the Product Life Cycle.'' This public workshop is intended to provide... discussed at the workshop: (1) Standards and guidance, (2) risk management in design, (3) risk management in...

  14. Analysis of the effect of risk management practices on the performance of new product development programs

    DEFF Research Database (Denmark)

    Oehmen, Josef; Olechowski, Alison; Kenley, C. Robert

    2014-01-01

    Risk management is receiving much attention, as it is seen as a method to improve cost, schedule, and technical performance of new product development programs. However, there is a lack of empirical research that investigates the effective integration of specific risk management practices proposed...... skills and resources; (2) Tailor risk management to and integrate it with new product development; (3) Quantify impacts of risks on your main objectives; (4) Support all critical decisions with risk management results; (5) Monitor and review your risks, risk mitigation actions, and risk management...... by various standards with new product development programs and their association with various dimensions of risk management success. Based on a survey of 291 product development programs, this paper investigates the association of risk management practices with five categories of product development program...

  15. Opportunity Loss Minimization and Newsvendor Behavior

    Directory of Open Access Journals (Sweden)

    Xinsheng Xu

    2017-01-01

    Full Text Available To study the decision bias in newsvendor behavior, this paper introduces an opportunity loss minimization criterion into the newsvendor model with backordering. We apply the Conditional Value-at-Risk (CVaR measure to hedge against the potential risks from newsvendor’s order decision. We obtain the optimal order quantities for a newsvendor to minimize the expected opportunity loss and CVaR of opportunity loss. It is proven that the newsvendor’s optimal order quantity is related to the density function of market demand when the newsvendor exhibits risk-averse preference, which is inconsistent with the results in Schweitzer and Cachon (2000. The numerical example shows that the optimal order quantity that minimizes CVaR of opportunity loss is bigger than expected profit maximization (EPM order quantity for high-profit products and smaller than EPM order quantity for low-profit products, which is different from the experimental results in Schweitzer and Cachon (2000. A sensitivity analysis of changing the operation parameters of the two optimal order quantities is discussed. Our results confirm that high return implies high risk, while low risk comes with low return. Based on the results, some managerial insights are suggested for the risk management of the newsvendor model with backordering.

  16. Labour Market Flexibility between Risk and Opportunity for Gender Equality Analyses of Self-employment, Part-time Work, and Job Autonomy

    OpenAIRE

    König, Stefanie

    2016-01-01

    The dissertation “Labour Market Flexibility between Risk and Opportunity for Gender Equality – Analyses of Self-employment, Part-time Work, and Job Autonomy” addresses the main research question: Is flexibility the key to a less gendered labour market, or does it rather foster more traditional roles and gender inequality? In four empirical studies, different aspects in life were investigated in order to gain a holistic understanding of gender inequalities related to flexibility at work: the d...

  17. Characterizing risk factors for pediatric lamp oil product exposures.

    Science.gov (United States)

    Sheikh, S; Chang, A; Kieszak, S; Law, R; Bennett, H K W; Ernst, E; Bond, G R; Spiller, H A; Schurz-Rogers, H; Chu, A; Bronstein, A C; Schier, J G

    2013-11-01

    Poisonings from lamp oil ingestion continue to occur worldwide among the pediatric population despite preventive measures such as restricted sale of colored and scented lamp oils. This suggests that optimal prevention practices for unintentional pediatric exposures to lamp oil have yet to be identified and/or properly implemented. To characterize demographic, health data, and potential risk factors associated with reported exposures to lamp oil by callers to poison centers (PCs) in the US and discuss their public health implications. This was a two part study in which the first part included characterizing all exposures to a lamp oil product reported to the National Poison Data System (NPDS) with regard to demographics, exposure, health, and outcome data from 1/1/2000 to 12/31/2010. Regional penetrance was calculated using NPDS data by grouping states into four regions and dividing the number of exposure calls by pediatric population per region (from the 2000 US census). Temporal analyses were performed on NPDS data by comparing number of exposures by season and around the July 4th holiday. Poisson regression was used to model the count of exposures for these analyses. In the second part of this project, in order to identify risk factors we conducted a telephone-based survey to the parents of children from five PCs in five different states. The 10 most recent lamp oil product exposure calls for each poison center were systematically selected for inclusion. Calls in which a parent or guardian witnessed a pediatric lamp oil product ingestion were eligible for inclusion. Data on demographics, exposure information, behavioral traits, and health were collected. A descriptive analysis was performed and Fisher's exact test was used to evaluate associations between variables. All analyses were conducted using SAS v9.3. Among NPDS data, 2 years was the most common patient age reported and states in the Midwestern region had the highest numbers of exposure calls compared to

  18. Calculating sales prices for natural gas. Securing success through an assessment of risks and opportunities; Vertriebspreiskalkulation Erdgas. Erfolgssicherung durch Chancen- und Risikobewertung

    Energy Technology Data Exchange (ETDEWEB)

    Gumbel, Steffen; Henze, Michael [energie quader GmbH, Darmstadt (Germany)

    2011-11-15

    Over the past years the gas market, which was once entirely supply-driven, has developed more and more into a buyer's market. Gas supply companies increasingly see themselves confronted with more innovative and varied supply inquiries from their customers. With sales margins increasingly coming under pressure, this often leaves no option but to give close consideration to the appropriate risk premium. This creates an urgent need to review existing risk assessment methods and put a stronger focus on possible opportunities.

  19. Valorizzazione e promozione cineturistica delle destinazioni: opportunità e rischi del marketing territoriale / Enhancement and cine-touristic promotion of destinations: opportunities and risks of territorial marketing

    Directory of Open Access Journals (Sweden)

    Rosy Scarlata

    2016-05-01

    Full Text Available Lo scopo principale di questo contributo consiste nel proporre uno spunto di riflessione circa le relazioni che intercorrono fra la proiezione di un film o di una serie televisiva, il cineturismo e la creazione dell’identità di un luogo. La disamina della letteratura esistente ha confermato l’esistenza di numerosi studi focalizzati sui forti impatti prodotti dal cineturismo, con il rischio di compromettere la capacità di carico dei territori e la sostenibilità delle attività turistiche. Minore interesse, invece, è stato rivolto a casi di studio che riguardano le ripercussioni di paesaggi non attrattivi, di trame negative e screditanti, con il risultato di veicolare un’immagine avversa alla destinazione, anche indipendentemente dal fenomeno cineturistico che potrebbe prodursi. Il presente contributo è il tentativo iniziale di approfondire questo aspetto, citando alcune esperienze italiane, e prendendo in considerazione il ruolo delle Film Commission nella creazione di immagini che siano confacenti alla identità territoriale che si intende promuovere all’esterno. The main focus of this article is to provide an opportunity to reflect upon the relationship between the production of a movie (or a tv series, the film-induced tourism and the creation of the identity of a place. A review of the existing literature revealed that many studies focused on the strongest impacts of film-induced tourism, with the risk of endangering the carrying capacity of territories and the  sustainability of tourist activities. Less attention has been paid to case-studies showing the effects of unattractive landscapes or negative and discrediting storylines portraying an image which is adverse to the destination. This paper is an initial attempt to discuss this issue and to fill this gap, by showing some recent Italian experiences and by taking into consideration the role of the Film Commissions in order to govern the creation of images which are fitting

  20. Risk assessment for stonecutting enterprises Accidental risks in the course of petroleum production and stone extraction

    Science.gov (United States)

    Aleksandrova, A. J.; Timofeeva, S. S.

    2018-01-01

    The paper is devoted to the assessment of accidental risks occurring at the works engaged in stone extracting and petroleum production. Two basic kinds of accidents common for stone extracting and petroleum production have been chosen to be discussed in the part under consideration. The most dangerous accidental situation characteristic for a stone milling line is an unsanctioned explosion, UE, of blasting agents used for the development of stone deposits. The analysis of a risk occurrence in certain accidental situations is to be carried out. With reference to petroleum extraction, a combustibles and lubricants (C & L) explosion is the most dangerous of characteristic accidental situations. To reveal the most probable causes of accidental situations to be realized, a graph of cause and effect relations has been constructed for each of the accidental situations most probable causes to real situation of an accident. Disasters of a natural origin are the most probable causes of unsanctioned explosions at the deposits of stone raw materials. Technology related natural disasters are the most probable causes of unsanctioned explosions to be realized at multiple well platforms engaged in petroleum production.

  1. Discussion on the safety production risk managmeent of uranium mines

    International Nuclear Information System (INIS)

    Liu Bin; Luo Yun; Hu Penghua; Zhu Disi

    2009-01-01

    Based on the modern safety risk management theories and according to the actual situation, risk management for work safety in uranium mines is discussed from three aspects: risk identification,risk analysis and evaluation, and risk control. Referring to the '4M(Men,Machine,Medium,Management) factors' and 'Three types of hazards' theory, the classification of uranium mine accidents and risk factors are analyzed. In addition, the types and evaluation indexes of major risks of uranium mines as well as the 'spot, line, area' model of risk identification and analysis and the 'hierarchical' risk control mechanism are also studied. (authors)

  2. Challenges and opportunities in establishing scientific and regulatory standards for determining therapeutic equivalence of modified-release products: Workshop summary report.

    Science.gov (United States)

    Chen, Mei-Ling; Shah, Vinod P; Ganes, Derek; Midha, Kamal K; Caro, James; Nambiar, Prabu; Rocci, Mario L; Thombre, Avinash G; Abrahamsson, Bertil; Conner, Dale; Davit, Barbara; Fackler, Paul; Farrell, Colm; Gupta, Suneel; Katz, Russell; Mehta, Mehul; Preskorn, Sheldon H; Sanderink, Gerard; Stavchansky, Salomon; Temple, Robert; Wang, Yaning; Winkle, Helen; Yu, Lawrence

    2010-09-01

    Modified-release (MR) products are complex dosage forms designed to release drug in a controlled manner to achieve the desired efficacy and safety profiles. Inappropriate control of drug release from such products may result in reduced efficacy or increased toxicity. This paper is a summary report of the American Association of Pharmaceutical Scientists, International Pharmaceutical Federation, and Product Quality Research Institute workshop titled "Challenges and Opportunities in Establishing Scientific and Regulatory Standards for Assuring Therapeutic Equivalence of Modified Release Products", held October 1-2, 2009, in Baltimore, Maryland. The workshop provided an opportunity for pharmaceutical scientists from academia, industry, and regulatory agencies to discuss current regulatory expectations and industry practices for evaluating the pharmaceutical equivalence and bioequivalence of oral MR products. In the case of conventional monophasic MR formulations, the current regulatory approaches and criteria for bioequivalence evaluation were considered adequate for the assessment of therapeutic equivalence and inter-changeability of drug products. Additional measures may occasionally be needed to determine the bioequivalence of multiphasic MR products. The metric of partial AUC proposed by the US Food and Drug Administration received broad support as an additional measure for evaluating bioequivalence of multiphasic MR products designed to have a rapid onset of drug action followed by sustained response. The cutoff for partial AUCs may be based on the pharmacokinetic/pharmacodynamic or pharmacokinetic/ response characteristics of the products under examination. If the new metric is highly variable, the bioequivalence limits may be set based on the known within-subject variability for the reference product. The current regulatory approaches and criteria for bioequivalence evaluation were considered adequate for the assessment of therapeutic equivalence and

  3. Exploiting deterministic maintenance opportunity windows created by conservative engineering design rules that result in free time locked into large high-speed coupled production lines with finite buffers

    Directory of Open Access Journals (Sweden)

    Durandt, Casper

    2016-08-01

    Full Text Available Conservative engineering design rules for large serial coupled production processes result in machines having locked-in free time (also called ‘critical downtime’ or ‘maintenance opportunity windows’, which cause idle time if not used. Operators are not able to assess a large production process holistically, and so may not be aware that they form the current bottleneck – or that they have free time available due to interruptions elsewhere. A real-time method is developed to accurately calculate and display free time in location and magnitude, and efficiency improvements are demonstrated in large-scale production runs.

  4. Benefits and risks associated with genetically modified food products.

    Science.gov (United States)

    Kramkowska, Marta; Grzelak, Teresa; Czyżewska, Krystyna

    2013-01-01

    Scientists employing methods of genetic engineering have developed a new group of living organisms, termed 'modified organisms', which found application in, among others, medicine, the pharmaceutical industry and food distribution. The introduction of transgenic products to the food market resulted in them becoming a controversial topic, with their proponents and contestants. The presented study aims to systematize objective data on the potential benefits and risks resulting from the consumption of transgenic food. Genetic modifications of plants and animals are justified by the potential for improvement of the food situation worldwide, an increase in yield crops, an increase in the nutritional value of food, and the development of pharmaceutical preparations of proven clinical significance. In the opinions of critics, however, transgenic food may unfavourably affect the health of consumers. Therefore, particular attention was devoted to the short- and long-lasting undesirable effects, such as alimentary allergies, synthesis of toxic agents or resistance to antibiotics. Examples arguing for the justified character of genetic modifications and cases proving that their use can be dangerous are innumerable. In view of the presented facts, however, complex studies are indispensable which, in a reliable way, evaluate effects linked to the consumption of food produced with the application of genetic engineering techniques. Whether one backs up or negates transgenic products, the choice between traditional and non-conventional food remains to be decided exclusively by the consumers.

  5. Benefits and risks associated with genetically modified food products

    Directory of Open Access Journals (Sweden)

    Marta Kramkowska

    2013-09-01

    Full Text Available Scientists employing methods of genetic engineering have developed a new group of living organisms, termed ‘modified organisms’, which found application in, among others, medicine, the pharmaceutical industry and food distribution. The introduction of transgenic products to the food market resulted in them becoming a controversial topic, with their proponents and contestants. The presented study aims to systematize objective data on the potential benefits and risks resulting from the consumption of transgenic food. Genetic modifications of plants and animals are justified by the potential for improvement of the food situation worldwide, an increase in yield crops, an increase in the nutritional value of food, and the development of pharmaceutical preparations of proven clinical significance. In the opinions of critics, however, transgenic food may unfavourably affect the health of consumers. Therefore, particular attention was devoted to the short- and long-lasting undesirable effects, such as alimentary allergies, synthesis of toxic agents or resistance to antibiotics. Examples arguing for the justified character of genetic modifications and cases proving that their use can be dangerous are innumerable. In view of the presented facts, however, complex studies are indispensable which, in a reliable way, evaluate effects linked to the consumption of food produced with the application of genetic engineering techniques. Whether one backs up or negates transgenic products, the choice between traditional and non-conventional food remains to be decided exclusively by the consumers.

  6. Hedging endowment assurance products under interest rate and mortality risk

    NARCIS (Netherlands)

    Chen, A.; Mahayni, A.

    2007-01-01

    This paper analyzes how model misspecification associated with both interest rate and mortality risk influences hedging decisions of insurance companies. For this purpose, diverse risk management strategies which are riskminimizing when model risk is ignored come into consideration. The

  7. Risk of discontinuation of Advanced Therapy Medicinal Products clinical trials.

    Science.gov (United States)

    Hanna, Eve; Rémuzat, Cecile; Auquier, Pascal; Toumi, Mondher

    2016-01-01

    Advanced therapy medicinal products (ATMPs) constitute a class of innovative products that encompasses gene therapy, somatic cell therapy, and tissue-engineered products (TEP). There is an increased investment of commercial and non-commercial sponsors in this field and a growing number of ATMPs randomized clinical trials (RCT) and patients enrolled in such trials. RCT generate data to prove the efficacy of a new therapy, but the discontinuation of RCTs wastes scarce resources. Our objective is to identify the number and characteristics of discontinued ATMPs trials in order to evaluate the rate of discontinuation. We searched for ATMPs trials conducted between 1999 to June 2015 using three databases, which are Clinicaltrials.gov, the International Clinical Trials Registry Platform (ICTRP), and the EU Drug Regulating Authorities Clinical Trials (EudraCT). We selected the ATMPs trials after elimination of the duplicates. We identified the disease areas and the sponsors as commercial or non-commercial organizations. We classified ATMPs by type and trial status, that is, ongoing, completed, terminated, discontinued, and prematurely ended. Then, we calculated the rate of discontinuation. Between 1999 and June 2015, 143 withdrawn, terminated, or prematurely ended ATMPs clinical trials were identified. Between 1999 and June 2013, 474 ongoing and completed clinical trials were identified. Therefore, the rate of discontinuation of ATMPs trials is 23.18%, similar to that for non-ATMPs drugs in development. The probability of discontinuation is, respectively, 27.35, 16.28, and 16.34% for cell therapies, gene therapies, and TEP. The highest discontinuation rate is for oncology (43%), followed by cardiology (19.2%). It is almost the same for commercial and non-commercial sponsors; therefore, the discontinuation reason may not be financially driven. No failure risk rate per development phase is available for ATMPs. The discontinuation rate may prove helpful when assessing the

  8. Two agricultural production data libraries for risk assessment models

    International Nuclear Information System (INIS)

    Baes, C.F. III; Shor, R.W.; Sharp, R.D.; Sjoreen, A.L.

    1985-01-01

    Two data libraries based on the 1974 US Census of Agriculture are described. The data packages (AGDATC and AGDATG) are available from the Radiation Shielding Information Center (RSIC), Oak Ridge National Laboratory, Oak Ridge, Tennessee 37831. Agricultural production and land-use information by county (AGDATC) or by 1/2 by 1/2 degree longitude-latitude grid cell (AGDATG) provide geographical resolution of the data. The libraries were designed for use in risk assessment models that simulate the transport of radionuclides from sources of airborne release through food chains to man. However, they are also suitable for use in the assessment of other airborne pollutants that can affect man from a food ingestion pathway such as effluents from synfuels or coal-fired power plants. The principal significance of the data libraries is that they provide default location-specific food-chain transport parameters when site-specific information are unavailable. Plant food categories in the data libraries include leafy vegetables, vegetables and fruits exposed to direct deposition of airborne pollutants, vegetables and fruits protected from direct deposition, and grains. Livestock feeds are also tabulated in four categories: pasture, grain, hay, and silage. Pasture was estimated by a material balance of cattle and sheep inventories, forage feed requirements, and reported harvested forage. Cattle (Bos spp.), sheep (Ovis aries), goat (Capra hircus), hog (Sus scrofa), chicken (Gallus domesticus), and turkey (Meleagris gallopavo) inventories or sales are also tabulated in the data libraries and can be used to provide estimates of meat, eggs, and milk production. Honey production also is given. Population, irrigation, and meteorological information are also listed

  9. Evaluation of opportunities for heat integration of biomass-based Fischer–Tropsch crude production at Scandinavian kraft pulp and paper mill sites

    International Nuclear Information System (INIS)

    Ljungstedt, Hanna; Pettersson, Karin; Harvey, Simon

    2013-01-01

    This study investigates heat integrated production of FT (Fischer–Tropsch) crude, where excess heat from the FT crude plant is delivered to a typical Scandinavian pulp and paper mill that produces fine paper. The sizes of FT crude plants are quantified, when the amount of excess heat from the FT plant exactly matches the heating demand otherwise satisfied by the bark boiler at the mill, considering a number of development pathways at the mill, including various degrees of steam savings and biorefinery options, such as lignin extraction. Performance of integrated production is compared with that of an FT stand-alone plant on the basis of wood fuel-to-FT crude efficiency, GHG (greenhouse gas) emissions balances and FT crude production cost. The results show that there exists a heat integration opportunity for an FT crude plant ranging from 0 up to 350 MW (LHV) of wood fuel depending on the development pathway for the mill. The results indicate higher overall efficiency and a generally lower production cost for the heat integrated, co-located production. Heat integrated production has a larger potential to contribute to GHG emission mitigation, assuming a future generation of grid electricity emitting equal to or less than an NGCC (natural gas combined cycle) power plant. - Highlights: • We investigate opportunities for heat integrated FT crude production at a mill. • Typical kraft pulp and paper mills have a potential for heat integrated production. • We compare the heat integrated production with stand-alone FT crude production. • Higher efficiency and lower production cost for heat integrated production. • Reduction of GHG emissions is strongly dependent on grid electricity emissions

  10. Safely towards self-driving vehicles : new opportunities new risks and new challenges during the automation of the traffic system.

    NARCIS (Netherlands)

    Nes, C.N. van & Duivenvoorden, C.W.A.E.

    2017-01-01

    There are more and more systems on the market to support the driver in his vehicle. Step by step the automation of our vehicles increases, the traffic system is in a transition towards self-driving vehicles. The automation offers opportunities to make our traffic safer, cleaner and more efficient.

  11. A risk microbiological profile of the Australian red meat industry: risk ratings of hazard-product pairings.

    Science.gov (United States)

    Sumner, John; Ross, Tom; Jenson, Ian; Pointon, Andrew

    2005-11-25

    A risk profile of microbial hazards across the supply continuum for the beef, sheep and goat meat industries was developed using both a qualitative tool and a semi-quantitative, spreadsheet tool, Risk Ranger. The latter is useful for highlighting factors contributing to food safety risk and for ranking the risk of various product/pathogen combinations. In the present profile the qualitative tool was used as a preliminary screen for a wide range of hazard-product pairings while Risk Ranger was used to rank in order of population health risk pairings for which quantitative data were available and for assessing the effect of hypothetical scenarios. 'High' risk hazard-product pairings identified were meals contaminated with Clostridium perfringens provided by caterers which have not implemented HACCP; kebabs cross-contaminated by Salmonella present in drip trays or served undercooked; meals served in the home cross-contaminated with Salmonella. 'Medium' risk hazard-product pairings identified were ready-to-eat meats contaminated with Listeria monocytogenes and which have extended shelf life; Uncooked Comminuted Fermented Meat (UCFM)/Salami contaminated with Enterohaemorrhagic E. coli (EHEC) and Salmonella; undercooked hamburgers contaminated with EHEC; kebabs contaminated by Salmonella under normal production or following final "flash" heating. Identified 'low' risk hazard-product pairings included cooked, ready-to-eat sausages contaminated with Salmonella; UCFM/Salami contaminated with L. monocytogenes; well-cooked hamburgers contaminated with EHEC. The risk profile provides information of value to Australia's risk managers in the regulatory, processing and R&D sectors of the meat and meat processing industry for the purposes of identifying food safety risks in the industry and for prioritising risk management actions.

  12. Considerations on risks associated with the production of energy

    International Nuclear Information System (INIS)

    Hamel, P.E.

    1977-09-01

    Fear of the unknown can cause the public to perceive more risk in the generation of power by nuclear means than by other methods. In fact, the situation may be quite the opposite. Decisions based on risk analysis must take into account not only the technical assessment of risk but also the attitude of the public towards different kinds of risk. (LL)

  13. Strengthening the knowledge-policy interface through co-production of a climate adaptation plan: leveraging opportunities in Bergriver Municipality, South Africa

    CSIR Research Space (South Africa)

    Ziervogel, G

    2016-10-01

    Full Text Available plan was presented to the Bergrivier Council to secure buy-in from both the administrative and political spheres. Western Cape government officials, two Climate Systems Analysis Group climate scientists, councillors and officials attended... and innovation. c) d. Capacity opportunity: champions of co-production Deleted: The importance of leaders and champions has been widely cited as critical in driving urban adaptation responses. (61) Maiello et al., (62) for example, observe that public...

  14. Quantitative Estimation of Risks for Production Unit Based on OSHMS and Process Resilience

    Science.gov (United States)

    Nyambayar, D.; Koshijima, I.; Eguchi, H.

    2017-06-01

    Three principal elements in the production field of chemical/petrochemical industry are (i) Production Units, (ii) Production Plant Personnel and (iii) Production Support System (computer system introduced for improving productivity). Each principal element has production process resilience, i.e. a capability to restrain disruptive signals occurred in and out of the production field. In each principal element, risk assessment is indispensable for the production field. In a production facility, the occupational safety and health management system (Hereafter, referred to as OSHMS) has been introduced to reduce a risk of accidents and troubles that may occur during production. In OSHMS, a risk assessment is specified to reduce a potential risk in the production facility such as a factory, and PDCA activities are required for a continual improvement of safety production environments. However, there is no clear statement to adopt the OSHMS standard into the production field. This study introduces a metric to estimate the resilience of the production field by using the resilience generated by the production plant personnel and the result of the risk assessment in the production field. A method for evaluating how OSHMS functions are systematically installed in the production field is also discussed based on the resilience of the three principal elements.

  15. Minimizing the risk and impact of uranium hexafluoride production

    International Nuclear Information System (INIS)

    Clark, D.R.; Kennedy, T.W.

    2010-01-01

    Cameco Corporation's Port Hope conversion facility, situated on the shore of Lake Ontario in the Municipality of Port Hope, Ontario, Canada, converts natural uranium trioxide (UO_3) into uranium dioxide (UO_2) or natural uranium hexafluoride (UF_6). Conversion of UO_3 to UF_6 has been undertaken at the Port Hope conversion facility since 1970 and is currently carried out in a second-generation plant licensed to annually produce 12,500 tonnes U as UF_6. Consistent with Cameco's vision, values and measures of success, Cameco recognizes safety and health of its workers and the public, protection of the environment, and the quality of our processes as the highest corporate priorities. Production of UF_6 in a brownfield urban setting requires a commitment to design, build and maintain multiple layers of containment (defence-in-depth) and to continually improve in all operational aspects to achieve this corporate commitment. This paper will describe the conversion processes utilized with a focus on the cultural, management and physical systems employed to minimize the risk and impact of the operation. (author)

  16. Opportunities for implementation of concepts and tools lean production aiming to improve competitiveness of enterprises of shoe APL Jaú / SP

    Directory of Open Access Journals (Sweden)

    Célio Favoni

    2013-08-01

    Full Text Available Lean production has been applied by organizations around the world as part of strategy to reduce waste in their value stream intending to improve performance. Despite the use of lean production concepts and tools have continually been introduced in different companies, the literature shows the most of application is identified in large companies than in Small-and  Medium-sized Enterprises (SMEs. The reason can be the lack of financial and human resources available to the lean initiatives in these enterprises. However, a wide range of concepts and techniques of lean production can be applied without considerable financial investments. This paper aims to study the opportunities and difficulties of lean production applicability in SMEs. Case research was developed in three SMEs of industrial cluster of Jaú/SP and the results suggest that these companies face similar difficulties. Nevertheless, the study confirms that there are several opportunities to implement lean production concepts and techniques which can lead to improve performance in these companies.

  17. Missed opportunities-adolescents with a chronic condition (insulin-dependent diabetes mellitus) describe their cigarette-smoking trajectories and consider health risks.

    Science.gov (United States)

    Regber, Susann; Kelly, Kristina Berg

    2007-12-01

    To enhance our knowledge on why adolescents with a chronic condition (insulin-dependent diabetes mellitus, IDDM) choose to smoke despite possible awareness of health risks. Twelve patients aged 15-20 with IDDM who smoked cigarettes volunteered to participate in qualitative interviews. The results were analyzed with content analysis according to Miles and Huberman 1994. One set confirmed what is earlier known on cigarette smoking among adolescents, such as plain exploring, needs to conform with group norms, identity needs and denial of risks. Other themes gave new insights. One was the emotional attitudes-or lack of emotions-expressed by important others, which exerted strong influences on the smoking trajectories. These emotions affected both initiation and motivation for quitting cigarette smoking and seemed crucial as means of meaningful communications concerning smoking. One theme was a flow path of cigarette smoking, which demonstrated opportunities for secondary prevention. Finally, developmental reasons for smoking and motivation for quitting could be described. There are several windows of opportunities to lower the risk of adolescents with IDDM and other chronic conditions from becoming and remaining smokers, as reported by young people themselves.

  18. Changing the paradigm of organ utilization from PHS increased-risk donors: an opportunity whose time has come?

    Science.gov (United States)

    Sibulesky, Lena; Javed, Imran; Reyes, Jorge D; Limaye, Ajit P

    2015-09-01

    Approximately 8-11% of all organ donors are classified by Public Health Service (PHS) as increased-risk. The proportion of PHS increased-risk donors is on the rise. At the University of Washington Medical Center, in 2014, the proportion of transplants from PHS increased-risk donors was 28% of liver transplants and 23% of kidney transplants. Nationally, transplant providers have been reluctant to use organs from PHS increased-risk donors because of concern for transmission of HIV, HCV, or HBV. There is also patient apprehension when these organs are being offered, and thus the discard rate of these otherwise good quality organs is high. Because of the organ shortage, preventing underutilization of such organs is essential. We provide data and considerations that should be used to guide the use of organs from PHS increased-risk donors. © 2015 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  19. Investigation of productivity in a south Indian Malabari goat herd shows opportunities for planned animal health management to improve food security.

    Science.gov (United States)

    Sargison, N D; Ivil, S A J; Abraham, J; Abubaker, S P S; Hopker, A M; Mazeri, S; Otter, I A; Otter, N

    2017-03-18

    Here the authors report the objective veterinary clinical measurement of productivity in a representative south Indian Malabari goat herd. The authors show failure to meet pragmatic production targets that are commensurate with the animals' genetic potential or adequate to meet the demands of global food security. The authors suggest that this situation may have arisen as a consequence of animal husbandry constraints and protein undernutrition and imply the involvement of nematode parasitism. Benzimidazole resistance was detected in Haemonchus species, showing the need for better understanding of the principles of sustainable helminth parasite control within the southern Indian context. This study highlights the need to understand the true costs of goat production in seasonally resource-poor environments, while also considering its impact on the overall ecosystem in which the animals are placed. They conclude that pragmatic opportunities for improvements in goat production efficiency lie in the development of problem-focused planned animal health and nutrition management. British Veterinary Association.

  20. The association of health risks with on-the-job productivity.

    Science.gov (United States)

    Burton, Wayne N; Chen, Chin-Yu; Conti, Daniel J; Schultz, Alyssa B; Pransky, Glenn; Edington, Dee W

    2005-08-01

    Decreased on-the-job productivity represents a large yet poorly characterized indirect cost to employers. We studied the impact of employee health risk factors on self-reported worker productivity (presenteeism). Using a brief version of the Work Limitation Questionnaire incorporated into a Health Risk Appraisal, 28,375 employees of a national company responded to the survey. The association between health risks and work limitation and each of the four domains was examined. Percentage of lost productivity also was estimated. Ten of 12 health risk factors studied were significantly associated with self-reported work limitations. The strength of the associations varied between risks and the four domains of work limitation. Perception-related risk factors such as life dissatisfaction, job dissatisfaction, poor health, and stress showed the greatest association with presenteeism. As the number of self-reported health risk factors increased, so did the percentage of employees reporting work limitations. Each additional risk factor was associated with 2.4% excess productivity reduction. Medium and high-risk individuals were 6.2% and 12.2% less productive than low-risk individuals, respectively. The annual cost of lost productivity in this corporation was estimated at between 99Mdollars and 185Mdollars or between 1392dollars and 2592dollars per employee. Health risk factors represent additional causes of lost productivity.

  1. Recent advances in understanding the genetic resources of sheep breeds locally-adapted to the UK uplands : opportunities they offer for sustainable productivity.

    Directory of Open Access Journals (Sweden)

    Dianna eBowles

    2015-02-01

    Full Text Available Locally adapted breeds of livestock are of considerable interest since they represent potential reservoirs of adaptive fitness traits that may contribute to the future of sustainable productivity in a changing climate.Recent research, involving three hill sheep breeds geographically concentrated in the northern uplands of the UK has revealed the extent of their genetic diversity from one another and from other breeds. Results from the use of SNPs, microsatellites and retrovirus insertions are reviewed in the context of related studies on sheep breeds world-wide to highlight opportunities offered by the genetic resources of locally adapted hill breeds. One opportunity concerns reduced susceptibility to Maedi-Visna, a lentivirus with massive impacts on sheep health and productivity globally. In contrast to many mainstream breeds used in farming, each of the hill breeds analysed are likely to be far less susceptible to the disease threat. A different opportunity, relating specifically to the Herdwick breed, is the extent to which the genome of the breed has retained primitive features, no longer present in other mainland breeds of sheep in the UK and offering a new route for discovering unique genetic traits of use to agriculture.

  2. A Retrospective Study of the Incidence of Missed Opportunities in Identifying, Managing and Referring At-Risk of Overweight and Overweight Children and Adolescents in an Outpatient Primary Care Setting

    National Research Council Canada - National Science Library

    Quirke, Amy

    2004-01-01

    A descriptive study of the incidence of missed opportunities in identifying, managing and referring children and adolescents at-risk of overweight and overweight were conducted using a retrospective...

  3. Comparative evaluation by lifecycle and risk assessment of agrobiological and technological routes of production

    NARCIS (Netherlands)

    Moll, H.C.; Schoot Uiterkamp, A.J.M.

    The application of lifecycle and risk assessment methodologies for environmental assessment of agricultural products is growing and produces interesting results. This allows comparisons between agricultural and technological routes of production. An evaluation of such assessments provides increased

  4. Preoperative therapy with pazopanib in high-risk soft tissue sarcoma: a phase II window-of-opportunity study by the German Interdisciplinary Sarcoma Group (GISG-04/NOPASS).

    Science.gov (United States)

    Ronellenfitsch, Ulrich; Dimitrakopoulou-Strauss, Antonia; Jakob, Jens; Kasper, Bernd; Nowak, Kai; Pilz, Lothar R; Attenberger, Ulrike; Gaiser, Timo; Egerer, Gerlinde; Fröhling, Stefan; Derigs, Hans-Günter; Schwarzbach, Matthias; Hohenberger, Peter

    2016-01-06

    For resectable soft tissue sarcoma (STS), radical surgery, usually combined with radiotherapy, is the mainstay of treatment and the only potentially curative modality. Since surgery is often complicated by large tumour size and extensive tumour vasculature, preoperative treatment strategies with the aim of devitalising the tumour are being explored. One option is treatment with antiangiogenic drugs. The multikinase inhibitor pazopanib, which possesses pronounced antiangiogenic effects, has shown activity in metastatic and unresectable STS, but has so far not been tested in the preoperative setting. This open-label, multicentre phase II window-of-opportunity trial assesses pazopanib as preoperative treatment of resectable STS. Participants receive a 21-day course of pazopanib 800 mg daily during wait time for surgery. Major eligibility criteria are resectable, high-risk adult STS of any location, or metachronous solitary STS metastasis for which resection is planned, and adequate organ function and performance status. The trial uses an exact single-stage design. The primary end point is metabolic response rate (MRR), that is, the proportion of patients with >50% reduction of the mean standardised uptake value (SUVmean) in post-treatment compared to pre-treatment fluorodeoxyglucose positron emission tomography CT. The MRR below which the treatment is considered ineffective is 0.2. The MRR above which the treatment warrants further exploration is 0.4. With a type I error of 5% and a power of 80%, the sample size is 35 evaluable patients, with 12 or more responders as threshold. Main secondary end points are histopathological and MRI response, resectability, toxicity, recurrence-free and overall survival. In a translational substudy, endothelial progenitor cells and vascular epithelial growth factor receptor are analysed as potential prognostic and predictive markers. Approval by the ethics committee II, University of Heidelberg, Germany (2012-019F-MA), German Federal

  5. Risk assessment of exposure to radon decay products

    Energy Technology Data Exchange (ETDEWEB)

    Monchaux, G

    1999-07-01

    The aim of this project was to assess the risk due to inhalation of radon and its decay products using an horizontal approach across a large scale research programme. The central objective was the assessment of human risk which requires combination of several topics involving a multidisciplinary approach. In the Aerosol Studies Group, progress was achieved in improvement, calibration and automation of experimental techniques for continuous and integrated measurements of the unattached fraction f{sub p}- and equilibrium factor F- values. Measurements were performed to determine the variation of size distributions of unattached and aerosol-associated radon decay products under typical living conditions. All aerosol groups performed controlled chamber studies to understand the basic behaviour of airborne activity concentrations. Measurements were performed to determine neutralisation rates of {sup 218}Po, to understand the cluster growth with residence time and to understand the hygroscopic growth of aerosol particles. In the Modelling Group, the programme RADEP has been developed to calculate the weighted committed equivalent lung dose per unit exposure of radon progeny (H{sub w}/P{sub p}) which implements the ICRP Publication 66 Human Respiratory Tract Model (HRTM). The stochastic deposition model (IDEAL) has been compared with the deposition model used by the HRTM, and the agreement between the two deposition models was excellent. A deterministic radon progeny dosimetry model (RADOS) has been developed. This model includes all bronchial airway generations compared with the HRTM that groups the 16 airway generations into three regions. Initial calculations with RADOS show that the basal and secretory cell doses are slightly smaller compared with that of the HRTM. A sensitivity analysis has been performed that has identified those HRTM model parameters that most affect the Hw/Pp. A stochastic rat deposition model (RALMO) and a clearance model for the rat based on the

  6. Risk assessment of exposure to radon decay products

    International Nuclear Information System (INIS)

    Monchaux, G.

    1999-01-01

    The aim of this project was to assess the risk due to inhalation of radon and its decay products using an horizontal approach across a large scale research programme. The central objective was the assessment of human risk which requires combination of several topics involving a multidisciplinary approach. In the Aerosol Studies Group, progress was achieved in improvement, calibration and automation of experimental techniques for continuous and integrated measurements of the unattached fraction f p - and equilibrium factor F- values. Measurements were performed to determine the variation of size distributions of unattached and aerosol-associated radon decay products under typical living conditions. All aerosol groups performed controlled chamber studies to understand the basic behaviour of airborne activity concentrations. Measurements were performed to determine neutralisation rates of 218 Po, to understand the cluster growth with residence time and to understand the hygroscopic growth of aerosol particles. In the Modelling Group, the programme RADEP has been developed to calculate the weighted committed equivalent lung dose per unit exposure of radon progeny (H w /P p ) which implements the ICRP Publication 66 Human Respiratory Tract Model (HRTM). The stochastic deposition model (IDEAL) has been compared with the deposition model used by the HRTM, and the agreement between the two deposition models was excellent. A deterministic radon progeny dosimetry model (RADOS) has been developed. This model includes all bronchial airway generations compared with the HRTM that groups the 16 airway generations into three regions. Initial calculations with RADOS show that the basal and secretory cell doses are slightly smaller compared with that of the HRTM. A sensitivity analysis has been performed that has identified those HRTM model parameters that most affect the Hw/Pp. A stochastic rat deposition model (RALMO) and a clearance model for the rat based on the HRTM have been

  7. Factors to consider in developing individual pharmaceutical product quality risk profiles useful to government procurement agencies.

    Science.gov (United States)

    Xu, Wei; Boehm, Garth; Zheng, Qiang

    2016-01-01

    Governments that procure pharmaceutical products from an Essential Medicine List (EML) bear special responsibility for the quality of these products. In this article we examine the possibility of developing a pharmaceutical product quality risk assessment scheme for use by government procurement officials. We use the Chinese EML as a basis, and US recall data is examined as it is publically available.This is justified as the article is only concerned with inherent product quality risks. After establishing a link between Chinese essential medicines and those available in the US, we examine US recall data to separate product specific recalls. We conclude that, in addition to existing manufacturing based risks, there are two other product specific risks that stand out from all others, degradation and dissolution failure. Methodology for relative product risk for degradation is needed to be developed and further work is required to better understand dissolution failures which largely occur with modified-release solid oral products. We conclude that a product specific quality risk profile would be enhanced by including a risk assessment for degradation for all products, and in the case of solid oral products, dissolution.

  8. ABC Classification of Risk Factors in Production Supply Chains with Uncertain Data

    Directory of Open Access Journals (Sweden)

    Aleksandar Vujović

    2017-01-01

    Full Text Available The problem of classification of risk factors in an uncertain environment is part of the risk management problem, which has a critical effect on the competitive advantage of production supply chain. The severities of consequences, their relative importance, and the frequency of occurrence of risk factors are defined by risk management team, depending on their experience and the results of good practice. Fuzzy rating of the severities of consequences and the frequency of occurrence of risk factors are described by linguistic expressions, which are modeled by triangular fuzzy numbers. The risk values, obtained by the materialization of the identified risk factors, are given precisely with the usage of fuzzy algebra rules. The classification criterion is defined as the distance between current risk value and extreme risk values. The proposed model enables determination of the priorities of risk factors. It is illustrated by an example with real-life data from a production supply chain in auto industry.

  9. Dairy product consumption and risk of colorectal cancer in an older mediterranean population at high cardiovascular risk.

    Science.gov (United States)

    Barrubés, Laura; Babio, Nancy; Mena-Sánchez, Guillermo; Toledo, Estefania; Ramírez-Sabio, Judith B; Estruch, Ramón; Ros, Emilio; Fitó, Montserrat; Arós, Fernando; Fiol, Miquel; Santos-Lozano, José Manuel; Serra-Majem, Lluís; Pintó, Xavier; Martínez-González, Miguel Ángel; Sorlí, José Vicente; Basora, Josep; Salas-Salvadó, Jordi

    2018-04-16

    Prospective studies have reported an inverse association between the consumption of total dairy products and milk and the risk of colorectal cancer (CRC). Nonetheless, there is little and inconsistent evidence regarding subtypes of dairy product and CRC risk. We assessed the associations between the consumption of total dairy products, their different subtypes and CRC risk in older Mediterranean individuals at high cardiovascular risk. We analyzed data from 7,216 men and women (55-80 years) without CRC at baseline from the PREvención con DIeta MEDiterránea study. Individuals were recruited between 2003 and 2009 and followed up until December 2012. At baseline and yearly thereafter, consumption of total and specific dairy products was assessed using a validated 137-item food-frequency questionnaire. Cox proportional hazards ratios (HRs) of CRC incidence were estimated for tertiles of mean consumption of dairy products during the follow-up. During a median [interquartile range] follow-up of 6.0 [4.4-7.3] years, we documented 101 incident CRC cases. In the multivariable-adjusted models, HRs and 95% confidence intervals (CIs) of CRC for the comparison of extreme tertiles of total dairy product and low-fat milk consumption were 0.55 (95% CI: 0.31-0.99; p-trend = 0.037) and 0.54 (95% CI: 0.32-0.92; p-trend = 0.022), respectively. No significant associations with other dairy products (whole-fat and low-fat dairy products; total, low-fat and whole-fat yogurt; cheese; total, low-fat and whole-fat milk; concentrated full-fat dairy products, sugar-enriched dairy products and fermented dairy products) were found. A high consumption of total dairy products and low-fat milk was significantly associated with a reduced CRC risk. © 2018 UICC.

  10. Longevity Risk and Natural Hedge Potential in Portfolios Of Life Insurance Products : The Effect of Investment Risk

    NARCIS (Netherlands)

    Stevens, R.S.P.; De Waegenaere, A.M.B.; Melenberg, B.

    2011-01-01

    Payments of life insurance products depend on the uncertain future evolution of survival probabilities. This uncertainty is referred to as longevity risk. Existing literature shows that the effect of longevity risk on single life annuities can be substantial, and that there exists a (natural) hedge

  11. Microbiological sampling plan based on risk classification to verify supplier selection and production of served meals in food service operation.

    Science.gov (United States)

    Lahou, Evy; Jacxsens, Liesbeth; Van Landeghem, Filip; Uyttendaele, Mieke

    2014-08-01

    Food service operations are confronted with a diverse range of raw materials and served meals. The implementation of a microbial sampling plan in the framework of verification of suppliers and their own production process (functionality of their prerequisite and HACCP program), demands selection of food products and sampling frequencies. However, these are often selected without a well described scientifically underpinned sampling plan. Therefore, an approach on how to set-up a focused sampling plan, enabled by a microbial risk categorization of food products, for both incoming raw materials and meals served to the consumers is presented. The sampling plan was implemented as a case study during a one-year period in an institutional food service operation to test the feasibility of the chosen approach. This resulted in 123 samples of raw materials and 87 samples of meal servings (focused on high risk categorized food products) which were analyzed for spoilage bacteria, hygiene indicators and food borne pathogens. Although sampling plans are intrinsically limited in assessing the quality and safety of sampled foods, it was shown to be useful to reveal major non-compliances and opportunities to improve the food safety management system in place. Points of attention deduced in the case study were control of Listeria monocytogenes in raw meat spread and raw fish as well as overall microbial quality of served sandwiches and salads. Copyright © 2014 Elsevier Ltd. All rights reserved.

  12. Opportunity Design

    DEFF Research Database (Denmark)

    Løwe Nielsen, Suna; Lassen, Astrid Heidemann; Nielsen, Louise Møller

    2013-01-01

    design”. The framework explains how opportunities intentionally and pro-actively can be designed from methods and processes of moving-in and moving-out. An illustrative case of opportunity design within the area of sustainable energy and electric cars is presented to link the theoretical discussion...

  13. Business opportunities

    Science.gov (United States)

    Los Alamos National Laboratory Search Site submit About Mission Business Newsroom Publications Los : Environmental Documents, Reports LANL Home Calendar Search Contacts Business » Short- and long-term opportunities Business opportunities Setting new standards and developing small business initiatives within NNSA

  14. Assessing the landscape context and conversion risk of protected areas using satellite data products

    Science.gov (United States)

    Svancara, Leona K.; Scott, J.M.; Loveland, Thomas R.; Pidgorna, Anna

    2009-01-01

    Since the establishment of the first national park (Yellowstone National Park in 1872) and the first wildlife refuge (Pelican Island in 1903), dramatic changes have occurred in both ecological and cultural landscapes across the U.S. The ability of these protected areas to maintain current levels of biodiversity depend, at least in part, on the integrity of the surrounding landscape. Our objective was to quantify and compare the extent and pattern of natural land cover, risk of conversion, and relationships with demographic and economic variables in counties near National Park Service units and U.S. Fish and Wildlife Service refuges with those counties distant from either type of protected area in the coterminous United States. Our results indicate that landscapes in counties within 10 km of both parks and refuges and those within 10 km of just parks were more natural, more intact, and more protected than those in counties within 10 km of just refuges and counties greater than 10 km from either protected area system. However, they also had greater human population density and change in population, indicating potential conversion risk since the percent of landscape protected averaged  2) in 76% of counties near both parks and refuges, 81% of counties near just parks, 91% of counties near just refuges, and 93% of distant counties. Thirteen percent of counties in the coterminous U.S. had moderate to high amounts of natural land cover (> 60%), low protection ( 20%). Although these areas are not the most critically endangered, they represent the greatest conservation opportunity, need, and urgency. Our approach is based on national level metrics that are simple, general, informative, and can be understood by broad audiences and by policy makers and managers to assess the health of lands surrounding parks and refuges. Regular monitoring of these metrics with satellite data products in counties surrounding protected areas provides a consistent, national level

  15. Tuberculosis and mass gatherings-opportunities for defining burden, transmission risk, and the optimal surveillance, prevention, and control measures at the annual Hajj pilgrimage.

    Science.gov (United States)

    Zumla, Alimuddin; Saeed, Abdulaziz Bin; Alotaibi, Badriah; Yezli, Saber; Dar, Osman; Bieh, Kingsley; Bates, Matthew; Tayeb, Tamara; Mwaba, Peter; Shafi, Shuja; McCloskey, Brian; Petersen, Eskild; Azhar, Esam I

    2016-06-01

    Tuberculosis (TB) is now the most common infectious cause of death worldwide. In 2014, an estimated 9.6 million people developed active TB. There were an estimated three million people with active TB including 360000 with multidrug-resistant TB (MDR-TB) who were not diagnosed, and such people continue to fuel TB transmission in the community. Accurate data on the actual burden of TB and the transmission risk associated with mass gatherings are scarce and unreliable due to the small numbers studied and methodological issues. Every year, an estimated 10 million pilgrims from 184 countries travel to the Kingdom of Saudi Arabia (KSA) to perform the Hajj and Umrah pilgrimages. A large majority of pilgrims come from high TB burden and MDR-TB endemic areas and thus many may have undiagnosed active TB, sub-clinical TB, and latent TB infection. The Hajj pilgrimage provides unique opportunities for the KSA and the 184 countries from which pilgrims originate, to conduct high quality priority research studies on TB under the remit of the Global Centre for Mass Gatherings Medicine. Research opportunities are discussed, including those related to the definition of the TB burden, transmission risk, and the optimal surveillance, prevention, and control measures at the annual Hajj pilgrimage. The associated data are required to develop international recommendations and guidelines for TB management and control at mass gathering events. Copyright © 2016 The Authors. Published by Elsevier Ltd.. All rights reserved.

  16. Sostenere le produzioni cinematografiche: vantaggi fiscali e di immagine per gli investitori / Sustaining cinematographic productions: fiscal and image opportunities for investors

    Directory of Open Access Journals (Sweden)

    Katia Giusepponi

    2016-05-01

    Full Text Available Questo contributo è focalizzato su organizzazioni non appartenenti al settore cinematografico, osservate nel loro ruolo di investitori esterni. L’importanza del valore collettivo di sostenere le produzioni cineaudiovisive è alla base del presente lavoro. Tuttavia la nostra attenzione è qui rivolta, da un lato, a studiare i vantaggi dell’investimento per l’azienda esterna, dall’altro, ad analizzarne i rischi nella prospettiva di una sempre più chiara consapevolezza di scelta. Dall’analisi di strumenti, dinamiche e dati emergono opportunità rilevanti per l’azienda, insieme a condizioni importanti per utilizzarle con successo. È essenziale che l’organizzazione proceda senza improvvisare, curando, da un lato, un approccio alla pianificazione e alla dettagliata valutazione del progetto, dall’altro, flessibilità e apertura nelle interazioni con gli altri interlocutori, interazioni che devono essere orientate al raggiungimento dell’equilibrio migliore a livello collettivo e individuale. Soprattutto, è necessario che l’azienda proceda nel contesto di un percorso strategico solido e coerente, perché un progetto di film può valorizzare l’identità aziendale ma non risolvere incertezze a questo riguardo.   This contribution focuses on organisations that are not in the cinema industry, studied in their role as external investors. The importance of the collective value of sustaining cine audio visual productions is at the basis of this work. Nonetheless, our attention is oriented, on one hand, to study the investment advantages for the external organization, on the other, to analyse the risks of this investment in the perspective of an increasingly clear choice. From the analysis of tools, dynamics and data, relevant opportunities for the organisation emerge, together with important conditions for their successful implementation. It is essential that the organization proceed without improvising, following, on one side, an

  17. From Process to Product: Your Risk Process at Work

    Science.gov (United States)

    Kundrot, Craig E.; Fogarty, Jenifer; Charles, John; Buquo, Lynn; Sibonga, Jean; Alexander, David; Horn, Wayne G.; Edwards, J. Michelle

    2010-01-01

    The Space Life Sciences Directorate (SLSD) and Human Research Program (HRP) at the NASA/Johnson Space Center work together to address and manage the human health and performance risks associated with human space flight. This includes all human system requirements before, during, and after space flight, providing for research, and managing the risk of adverse long-term health outcomes for the crew. We previously described the framework and processes developed for identifying and managing these human system risks. The focus of this panel is to demonstrate how the implementation of the framework and associated processes has provided guidance in the management and communication of human system risks. The risks of early onset osteoporosis, CO2 exposure, and intracranial hypertension in particular have all benefitted from the processes developed for human system risk management. Moreover, we are continuing to develop capabilities, particularly in the area of information architecture, which will also be described. We are working to create a system whereby all risks and associated actions can be tracked and related to one another electronically. Such a system will enhance the management and communication capabilities for the human system risks, thereby increasing the benefit to researchers and flight surgeons.

  18. Investigations regarding the lowering of specific intellectual property risks identified in the production process

    Directory of Open Access Journals (Sweden)

    Pakocs Ramona

    2017-01-01

    Full Text Available The main purpose of this research is to decrease the emergence of specific intellectual property risks within the production process as well as increasing risk management performance of IP by preventing them. In order to achieve this, previous studies regarding the main specific intellectual property risks from industrial companies were analyzed together with their managerial methods as well as the possibility of reducing their emergence. As a result of the research conducted were identified five types of intellectual property risks that have a high potential of emergence in the production process, namely: the risk of production of goods in violation of IP rights; the know-how, production knowledge and trade secret disclosure risk; the technological risk of unprotected utility models; the technological risk of unprotected integrated circuits topographies and finally the risk of product counterfeit. In order to achieve the main purpose of our investigation, we have proposed new formulas for estimating the specific intellectual property risks identified in the production process. Their purpose was to minimalize the risk’s negative effects on industrial companies and to increase the managerial performance from the intellectual property domain through a new type of management appropriately named: intellectual property management. The research is finalized with a case study regarding the lapse of rights of a patented invention. Based on a case analysis, it was proved that the exploitation of an invention without a contract represents a counterfeit.

  19. Environmental risk assessment for veterinary medicinal products. Part 1. Other than GMO-containing and immunological products. First update

    NARCIS (Netherlands)

    Montforts MHMM; CSR

    1999-01-01

    The EC has issued directives (1981, 1992) requesting for registration of veterinary medicinal product information to enable an assessment of the product's safety for the environment. As a whole, the risk assessment is structured around the hazard quotient approach used in USES (1994). Predicted

  20. Risk Adjusted Production Efficiency of Maize Farmers in Ethiopia: Implication for Improved Maize Varieties Adoption

    Directory of Open Access Journals (Sweden)

    Sisay Diriba Lemessa

    2017-09-01

    Full Text Available This study analyzes the technical efficiency and production risk of 862 maize farmers in major maize producing regions of Ethiopia. It employs the stochastic frontier approach (SFA to estimate the level of technical efficiencies of stallholder farmers. The stochastic frontier approach (SFA uses flexible risk properties to account for production risk. Thus, maize production variability is assessed from two perspectives, the production risk and the technical efficiency. The study also attempts to determine the socio-economic and farm characteristics that influence technical efficiency of maize production in the study area. The findings of the study showed the existence of both production risk and technical inefficiency in maize production process. Input variables (amounts per hectare such as fertilizer and labor positively influence maize output. The findings also show that farms in the study area exhibit decreasing returns to scale. Fertilizer and ox plough days reduce output risk while labor and improved seed increase output risk. The mean technical efficiency for maize farms is 48 percent. This study concludes that production risk and technical inefficiency prevents the maize farmers from realizing their frontier output. The best factors that improve the efficiency of the maize farmers in the study area include: frequency of extension contact, access to credit and use of intercropping. It was also realized that altitude and terracing in maize farms had influence on farmer efficiency.

  1. ANALYSIS OF RISK FACTORS AT THE STAGE OF THE PRODUCT LIFE CYCLE

    Directory of Open Access Journals (Sweden)

    N. Skopenko

    2016-10-01

    Full Text Available The article outlines and summarizes the risks of enterprises at different stages of product life cycle. A diagnose and assess of risks according to the main stages of the product development are offered. Groups of factors that shape the economic risks at different stages of the product life cycle, by the possible negative consequences of their impact are formulated. To reduce the probable losses of the company and a reasonable assortment portfolio formation generalized classification of risks that are typical for any company is proposed.

  2. Patient centric drug product design in modern drug delivery as an opportunity to increase safety and effectiveness.

    Science.gov (United States)

    Stegemann, Sven

    2018-06-01

    The advances in drug delivery technologies have enabled pharmaceutical scientists to deliver a drug through various administration routes and optimize the drug release and absorption. The wide range of drug delivery systems and dosage forms represent a toolbox of technology for the development of pharmaceutical drug products but might also be a source of medication errors and nonadherence. Patient centric drug product development is being suggested as an important factor to increase therapeutic outcomes. Areas covered: Patients have impaired health and potentially disabilities and they are not medical or pharmaceutical experts but are requested to manage complex therapeutic regimens. As such the application of technology should also serve to reduce complexity, build on patients' intuition and ease of use. Patients form distinct populations based on the targeted disease, disease cluster or age group with specific characteristics or therapeutic contexts. Expert opinion: Establishing a target product and patient profile is essential to guide drug product design development. Including the targeted patient populations in the process is a prerequisite to achieve patient-centric pharmaceutical drug product design. Addressing the needs early on in the product design process, will create more universal design, avoiding the necessity for multiple product presentations to cover the different patient populations.

  3. Junk Food, Health and Productivity: Taste, Price, Risk and Rationality

    OpenAIRE

    Levy, Amnon

    2006-01-01

    Junk-food consumption, health and productivity are analyzed within an expectedlifetime- utility-maximizing framework in which the probability of living and productivity rise with health and health deteriorate with the consumption of junkfood. So long that the junk food’s relative taste-price differential is positive, the rational diet deviates from the physiologically optimal and renders the levels of health and productivity lower than the maximal. Taxing junk-food can eliminate this discrepa...

  4. The Committed Intimate Partnerships of Incarcerated African-American Men: Implications for Sexual HIV Transmission Risk and Prevention Opportunities.

    Science.gov (United States)

    Khan, Maria R; El-Bassel, Nabila; Golin, Carol E; Scheidell, Joy D; Adimora, Adaora A; Coatsworth, Ashley M; Hu, Hui; Judon-Monk, Selena; Medina, Katie P; Wohl, David A

    2017-10-01

    Incarceration is thought to influence HIV transmission by disrupting partnerships that provide support and protect against sex risk-taking. Current correctional facility-based family-strengthening programs focus on marital partnerships, a minority of inmates' partnerships. Research on the sex partnerships of incarcerated African-American men and the types of partnerships most likely to protect against HIV-related sex risk is limited. Improved understanding can inform expansion of correctional facility-based family-strengthening programs to a greater proportion of protective partnerships and HIV risk reduction programs to partnerships vulnerable to sex risk. Project DISRUPT is a cohort study of African-American men being released from prison in North Carolina who were in committed heterosexual partnerships at prison entry. Using baseline survey data (N = 189), we conducted latent class analysis (LCA) to identify subgroups of participants with distinct relationship profiles and measured associations between relationship characteristics and multiple partnerships of inmates and their partners in the six months before incarceration. LCA indicated a two-class solution, with relationships distinguished by satisfaction/stability (satisfied/stable class: 58.0%; dissatisfied/unstable class: 42.0%); each class had comparable relationship length and levels of marriage and cohabitation. Dissatisfied/unstable relationships were associated with multiple partnerships among participants (AOR 2.93, 95% CI 1.50, 5.72) and partners (AOR 4.95, 95% CI 1.68, 14.58). Satisfaction indicators-versus length, marriage, or cohabitation-were the strongest independent correlates of inmates' and partners' multiple partnerships. Pre-incarceration economic deprivation, mental disorder symptoms, substance use, and violence in relationships were associated with dissatisfaction/instability. Prison-based programs designed to maintain healthy partnerships, strengthen relationship skills, and reduce

  5. How Does Risk Management Influence Production Decisions? Evidence from a Field Experiment

    OpenAIRE

    Cole, Shawn; Giné, Xavier; Vickery, James

    2013-01-01

    Weather is a key source of income risk for many firms and households, particularly in emerging market economies. This paper uses a randomized controlled trial approach to study how an innovative risk management instrument for hedging rainfall risk affects production decisions among a sample of Indian agricultural firms. The analysis finds that the provision of insurance induces farmers to ...

  6. The socioeconomic scenario and opportunities for mature production regions; O cenario socioeconomico e oportunidades de desenvolvimento para regioes produtoras maduras

    Energy Technology Data Exchange (ETDEWEB)

    Reis, Andrea Campos; Lima, Regina Celia Palacio

    2009-07-01

    It is shown that production of oil and gas in mature fields provides good conditions for the economic and social development of the producing regions. This article presents the current social-economic scenery in areas of mature production. The authors provide a comparison between collected royalties and human development indicator in some countries with analysis of socio-economic data and comparison of results with and without the collection of royalties. Additionally, this papers offers a study of the socio-economic motivations for production in mature fields and describes several initiatives for improving living conditions for the local population. (author)

  7. Managing Dry Spell Risks to Improve Rainfed Maize Productivity in ...

    African Journals Online (AJOL)

    Key words: Dry spell, Plant population, Risk, Soil water, Tillage, WRSI .... gravimetric method for each factor and treatment (Singh, 1997), while Crop Water ..... Decision Support system- a promising past, disappointing present and an uncertain ...

  8. International recommendations for managing environmental risk from nuclear energy production

    International Nuclear Information System (INIS)

    Clarke, R.H.

    1996-01-01

    The establishment of any recommendations relating to the control of radiation exposure requires decisions on the management of the associated risk. Those decisions must reflect attitudes towards the acceptable levels of risk for both workers and the public. The environmental impact of nuclear energy principally concerns radiation doses and risks to members of the public. The author shows how the considerations of risk and acceptability are used internationally to set standards for protection. The results differ as between limiting doses for normal operations, for restricting the likelihood of accidents, intervening after an accident, or reducing doses from a chronic exposure situation. It is concluded that there is a coherent pattern in the resulting protection system

  9. Weather swap as an instrument for weather risk management in wheat production

    Directory of Open Access Journals (Sweden)

    Marković Todor

    2012-01-01

    Full Text Available A special type of weather derivatives are weather forwards and they exists mostly in the form of weather swaps. Hedging effectiveness in wheat production with and without weather swap was analyzed in this paper using stochastic dominance. The results show that the effect of risk reduction is significant using weather swap, but geographical- basis risk and production-related basis risk are important factor that reduce the utility of weather derivatives.

  10. The risk analysis during production process of an innovative baby carriage with a bike function

    Directory of Open Access Journals (Sweden)

    Nowiński Emil

    2015-12-01

    Full Text Available The article presents the risk assesment of damages occurance in production stage of a babycarriage with a bike function. The analysis of risk is done by using the FMEA – Failure Made and Effect Analysis that is used in aviation and automotive industry. This way of innovative product assessment allows to evaluate the risk of defects and indicate the priorities of quality for key parts as well as the device.

  11. Job Stress Risk Factors Among Power Generation and Machine Production Employees: A Case Study-2010

    OpenAIRE

    Z. Naghavi; M.R. Hajgholami; Y. Shokoohi; F. Zayeri

    2013-01-01

    Background and Objective: Job stress has been adverse effects on performance, quality of work, absents, unsafe behaviors and occupational accidents and also health problems. Risk factors of job stress can be different in various workplaces. Risk factors determination is the first step of job stress management. Identifying these risk factors among workers of Power production & Machine production industries was the aim of this study. Methods: First parts of Osipow questionnaire was used for ...

  12. Applying quantitative benefit-risk analysis to aid regulatory decision making in diagnostic imaging: methods, challenges, and opportunities.

    Science.gov (United States)

    Agapova, Maria; Devine, Emily Beth; Bresnahan, Brian W; Higashi, Mitchell K; Garrison, Louis P

    2014-09-01

    Health agencies making regulatory marketing-authorization decisions use qualitative and quantitative approaches to assess expected benefits and expected risks associated with medical interventions. There is, however, no universal standard approach that regulatory agencies consistently use to conduct benefit-risk assessment (BRA) for pharmaceuticals or medical devices, including for imaging technologies. Economics, health services research, and health outcomes research use quantitative approaches to elicit preferences of stakeholders, identify priorities, and model health conditions and health intervention effects. Challenges to BRA in medical devices are outlined, highlighting additional barriers in radiology. Three quantitative methods--multi-criteria decision analysis, health outcomes modeling and stated-choice survey--are assessed using criteria that are important in balancing benefits and risks of medical devices and imaging technologies. To be useful in regulatory BRA, quantitative methods need to: aggregate multiple benefits and risks, incorporate qualitative considerations, account for uncertainty, and make clear whose preferences/priorities are being used. Each quantitative method performs differently across these criteria and little is known about how BRA estimates and conclusions vary by approach. While no specific quantitative method is likely to be the strongest in all of the important areas, quantitative methods may have a place in BRA of medical devices and radiology. Quantitative BRA approaches have been more widely applied in medicines, with fewer BRAs in devices. Despite substantial differences in characteristics of pharmaceuticals and devices, BRA methods may be as applicable to medical devices and imaging technologies as they are to pharmaceuticals. Further research to guide the development and selection of quantitative BRA methods for medical devices and imaging technologies is needed. Copyright © 2014 AUR. Published by Elsevier Inc. All rights

  13. Suicide in Illinois, 2005-2010: A reflection of patterns and risks by age groups and opportunities for targeted prevention.

    Science.gov (United States)

    McLone, Suzanne G; Loharikar, Anagha; Sheehan, Karen; Mason, Maryann

    2016-10-01

    Suicide accounts for two thirds of all deaths from intentional or violence-related injury and is a leading cause of death in the United States. Patterns of suicide have been well described among high-risk groups, but few studies have compared the circumstances related to suicides across all age groups. We sought to understand the epidemiology of suicide cases in Illinois and to characterize the risks and patterns for suicide among different age groups. We used suicide data collected from the Illinois Violent Death Reporting System to assess demographics, method of suicide, circumstances, and mental health status among different age groups. Between 2005 and 2010, 3,016 suicides were reported; 692 (23%) were female, and the median age (n = 3,013) was 45 years (range, 10-98 years). The most common method/weapon types were hanging/strangulation (33%), firearm (32%) and poisoning (21%). Hanging was more common (74%) among young people aged 10 to 19 years, while firearm use was more common among elderly persons age 65 years and older (55%). The percentage of victims within an age group experiencing a crisis within two weeks before committing suicide was highest among 10- to 14-year-olds, while the risk factor of having a family member or friend die in the past 5 years was highest among older victims. The final analysis demonstrated age-related trends in suicide in Illinois, suggesting prevention programs should tailor services by age. Epidemiologic study, level IV.

  14. The World Health Organization STEPwise Approach to Noncommunicable Disease Risk-Factor Surveillance: Methods, Challenges, and Opportunities.

    Science.gov (United States)

    Riley, Leanne; Guthold, Regina; Cowan, Melanie; Savin, Stefan; Bhatti, Lubna; Armstrong, Timothy; Bonita, Ruth

    2016-01-01

    We sought to outline the framework and methods used by the World Health Organization (WHO) STEPwise approach to noncommunicable disease (NCD) surveillance (STEPS), describe the development and current status, and discuss strengths, limitations, and future directions of STEPS surveillance. STEPS is a WHO-developed, standardized but flexible framework for countries to monitor the main NCD risk factors through questionnaire assessment and physical and biochemical measurements. It is coordinated by national authorities of the implementing country. The STEPS surveys are generally household-based and interviewer-administered, with scientifically selected samples of around 5000 participants. To date, 122 countries across all 6 WHO regions have completed data collection for STEPS or STEPS-aligned surveys. STEPS data are being used to inform NCD policies and track risk-factor trends. Future priorities include strengthening these linkages from data to action on NCDs at the country level, and continuing to develop STEPS' capacities to enable a regular and continuous cycle of risk-factor surveillance worldwide.

  15. Traditional alcohol production and use in three provinces in Vietnam: an ethnographic exploration of health benefits and risks

    Science.gov (United States)

    2014-01-01

    Background Gaps exist in knowledge about the production and use of traditional alcohols, particularly in Asia. This study adds new information about the nature, production and sale of traditional distilled spirit alcohol in Vietnam. Method This was an ethnographic study of traditional distilled spirit alcohol production in rural areas of three provinces in Vietnam. Researchers interviewed more than 300 individuals and recorded responses to general open-ended questions about local alcohol production. Interviews were recorded, transcribed, and studied to discern what information about traditional alcohol was important to the speakers. Results Methods of production followed long-held traditions. Participants listed both personal and community benefits (economic, health, and social) from traditional alcohol making. Older people favoured traditional alcohol, while younger people favoured brand-name beer. Typically people consumed 2-4 drinks daily, mainly at meal times. People consumed more alcohol at special events and festivals. Distribution patterns ranged from low-risk distribution to family and neighbours to high-risk distribution by an agent who might combine alcohol from several producers, which increases the opportunity for dilution and adulteration. The most commonly listed health risks associated with locally-made alcohol were local air pollution and water pollution; participants also mentioned traffic crashes and bad public behaviour. Depending on the location, community leaders reported that production may be relatively stable or it may be declining. Conclusions Traditional alcohol manufacture, sale, and use in Vietnam is a long-standing practice and low- to moderate-risk to health. There do not appear to be instances of accidental or intentional contamination. Urbanization seems to be affecting the market share of traditional alcohol as urbanized youth turn to branded products, mainly beer, making traditional alcohol making and consumption an activity mainly

  16. Traditional alcohol production and use in three provinces in Vietnam: an ethnographic exploration of health benefits and risks.

    Science.gov (United States)

    Luu, Bich Ngoc; Nguyen, Thi Thieng; Newman, Ian M

    2014-07-18

    Gaps exist in knowledge about the production and use of traditional alcohols, particularly in Asia. This study adds new information about the nature, production and sale of traditional distilled spirit alcohol in Vietnam. This was an ethnographic study of traditional distilled spirit alcohol production in rural areas of three provinces in Vietnam. Researchers interviewed more than 300 individuals and recorded responses to general open-ended questions about local alcohol production. Interviews were recorded, transcribed, and studied to discern what information about traditional alcohol was important to the speakers. Methods of production followed long-held traditions. Participants listed both personal and community benefits (economic, health, and social) from traditional alcohol making. Older people favoured traditional alcohol, while younger people favoured brand-name beer. Typically people consumed 2-4 drinks daily, mainly at meal times. People consumed more alcohol at special events and festivals. Distribution patterns ranged from low-risk distribution to family and neighbours to high-risk distribution by an agent who might combine alcohol from several producers, which increases the opportunity for dilution and adulteration. The most commonly listed health risks associated with locally-made alcohol were local air pollution and water pollution; participants also mentioned traffic crashes and bad public behaviour. Depending on the location, community leaders reported that production may be relatively stable or it may be declining. Traditional alcohol manufacture, sale, and use in Vietnam is a long-standing practice and low- to moderate-risk to health. There do not appear to be instances of accidental or intentional contamination. Urbanization seems to be affecting the market share of traditional alcohol as urbanized youth turn to branded products, mainly beer, making traditional alcohol making and consumption an activity mainly linked to older people in rural areas

  17. A practical discussion of risk management for manufacturing of pharmaceutical products.

    Science.gov (United States)

    Mollah, A Hamid; Baseman, Harold S; Long, Mike; Rathore, Anurag S

    2014-01-01

    Quality risk management (QRM) is now a regulatory expectation, and it makes good business sense. The goal of the risk assessment is to increase process understanding and deliver safe and effective product to the patients. Risk analysis and management is an acceptable and effective way to minimize patient risk and determine the appropriate level of controls in manufacturing. While understanding the elements of QRM is important, knowing how to apply them in the manufacturing environment is essential for effective process performance and control. This article will preview application of QRM in pharmaceutical and biopharmaceutical manufacturing to illustrate how QRM can help the reader achieve that objective. There are several areas of risk that a drug company may encounter in pharmaceutical manufacturing, specifically addressing oral solid and liquid formulations. QRM tools can be used effectively to identify the risks and develop strategy to minimize or control them. Risks are associated throughout the biopharmaceutical manufacturing process-from raw material supply through manufacturing and filling operations to final distribution via a controlled cold chain process. Assessing relevant attributes and risks for biotechnology-derived products is more complicated and challenging for complex pharmaceuticals. This paper discusses key risk factors in biopharmaceutical manufacturing. Successful development and commercialization of pharmaceutical products is all about managing risks. If a company was to take zero risk, most likely the path to commercialization would not be commercially viable. On the other hand, if the risk taken was too much, the product is likely to have a suboptimal safety and efficacy profile and thus is unlikely to be a successful product. This article addresses the topic of quality risk management with the key objective of minimizing patient risk while creating an optimal process and product. Various tools are presented to aid implementation of these

  18. Plant molecular farming: Opportunities and challenges

    Directory of Open Access Journals (Sweden)

    Valkova Rumyana

    2013-01-01

    Full Text Available The modern human life is impossible without products derived from the classical, contemporary biotechnology. However, large scale production of biotechnology wares opens a discussion about the economic impact, waste management, biosafety, and bioethical issues. Plant molecular farming offers a relatively inexpensive option for yielding of many valuable products and demonstrates number of advantages over the classical technologies, but also brings the question of further development perspectives, hazard identification and risk assessment. This review is focused on those two questions: opportunities offered and challenges faced by modern plant molecular farming systems.

  19. Guidelines for Risk-Based Changeover of Biopharma Multi-Product Facilities.

    Science.gov (United States)

    Lynch, Rob; Barabani, David; Bellorado, Kathy; Canisius, Peter; Heathcote, Doug; Johnson, Alan; Wyman, Ned; Parry, Derek Willison

    2018-01-01

    In multi-product biopharma facilities, the protection from product contamination due to the manufacture of multiple products simultaneously is paramount to assure product quality. To that end, the use of traditional changeover methods (elastomer change-out, full sampling, etc.) have been widely used within the industry and have been accepted by regulatory agencies. However, with the endorsement of Quality Risk Management (1), the use of risk-based approaches may be applied to assess and continuously improve established changeover processes. All processes, including changeover, can be improved with investment (money/resources), parallel activities, equipment design improvements, and standardization. However, processes can also be improved by eliminating waste. For product changeover, waste is any activity not needed for the new process or that does not provide added assurance of the quality of the subsequent product. The application of a risk-based approach to changeover aligns with the principles of Quality Risk Management. Through the use of risk assessments, the appropriate changeover controls can be identified and controlled to assure product quality is maintained. Likewise, the use of risk assessments and risk-based approaches may be used to improve operational efficiency, reduce waste, and permit concurrent manufacturing of products. © PDA, Inc. 2018.

  20. Assessing the transfer of risk due to transportation of agricultural products.

    Science.gov (United States)

    Li, Pei-Chiun; Shih, Hsiu-Ching; Ma, Hwong-Wen

    2015-02-01

    Health risk assessment (HRA) is the process used to estimate adverse health effects on humans. The importance and sensitivity of food chains to HRA have been observed, but the impact of the transportation of food has generally been ignored. This study developed an exposure assessment to demonstrate the significance of the transportation of agricultural products in HRA. The associated case study estimated the health risks derived from various sources of arsenic emissions in Taiwan. Two assessment scenarios, self-sufficiency and transportation of agricultural products, were compared to calculate risk transfer ratios that show the impact of agriculture transportation. The risk transfer ratios found by the study range from 0.22 to 42.10, indicating that the quantity of transportation of agricultural products is the critical factor. High air deposition and high agricultural production are the two main contributors to the effect of the transportation of agricultural products on HRA. Risk reduction measures could be applied to high-pollution areas as well as to areas with high agricultural productivity to reduce ingestion risks to residents. Certain areas that are sensitive to the transportation of agricultural products may incur more risks if emissions increase in agriculturally productive counties. Copyright © 2014 Elsevier Ltd. All rights reserved.

  1. Chemical and radiological risk factors associated with waste from energy production

    DEFF Research Database (Denmark)

    Christensen, T.; Fuglestvedt, J.; Benestad, C.

    1992-01-01

    We have tried to estimate the toxic potential of waste from nuclear power plants and from power plants burning fossil fuels. The potential risks have been expressed as 'risk potentials' or 'person equivalents'. These are purely theoretical units and represent only an attempt to quantify...... and one has to accept a certain small risk by accepting the concentration limit. This is in line with the establishment of limits for radiation. Waste products from coal combustion have the highest potential risk among the fossil fuel alternatives. The highest risk is caused by metals, and the fly ash...... represents the effluent stream giving the largest contribution to the potential risk. The waste from nuclear power production has a lower potential risk than coal if today's limit values are used. If one adjusts the limits for radiation dose and the concentration limit values so that a similar risk...

  2. Satellite Radiation Products for Ocean Biology and Biogeochemistry: Needs, State-of-the-Art, Gaps, Development Priorities, and Opportunities

    Directory of Open Access Journals (Sweden)

    Robert Frouin

    2018-02-01

    Full Text Available Knowing the spatial and temporal distribution of the underwater light field, i.e., the spectral and angular structure of the radiant intensity at any point in the water column, is essential to understanding the biogeochemical processes that control the composition and evolution of aquatic ecosystems and their impact on climate and reaction to climate change. At present, only a few properties are reliably retrieved from space, either directly or via water-leaving radiance. Existing satellite products are limited to planar photosynthetically available radiation (PAR and ultraviolet (UV irradiance above the surface and diffuse attenuation coefficient. Examples of operational products are provided, and their advantages and drawbacks are examined. The usefulness and convenience of these products notwithstanding, there is a need, as expressed by the user community, for other products, i.e., sub-surface planar and scalar fluxes, average cosine, spectral fluxes (UV to visible, diurnal fluxes, absorbed fraction of PAR by live algae (APAR, surface albedo, vertical attenuation, and heating rate, and for associating uncertainties to any product on a pixel-by-pixel basis. Methodologies to obtain the new products are qualitatively discussed in view of most recent scientific knowledge and current and future satellite missions, and specific algorithms are presented for some new products, namely sub-surface fluxes and average cosine. A strategy and roadmap (short, medium, and long term for usage and development priorities is provided, taking into account needs and readiness level. Combining observations from satellites overpassing at different times and geostationary satellites should be pursued to improve the quality of daily-integrated radiation fields, and products should be generated without gaps to provide boundary conditions for general circulation and biogeochemical models. Examples of new products, i.e., daily scalar PAR below the surface, daily average

  3. Moderating effect of perceived risk on the relationship between product safety and intention

    Directory of Open Access Journals (Sweden)

    Sarina Ismail

    2015-02-01

    Full Text Available Herbal Products industry has experienced significant growth in product demand. Therefore, this study aims to identify the factors effecting the actual buying of Herbal Product. This study also examines the moderation effect of perceived risk on the relationship between product safety and intention. Mall intercept survey was used to collect data from six various states in Malaysia. The data is analyzed using Partial Least Squares (PLS path modeling. The path coefficient results supported the direct influence of intention on actual buying. Similarly, the findings reveal that perceived risk moderate the relationship between product safety and buying intention.

  4. Environmental and risk screening for prioritizing pollution prevention opportunities in the U.S. printed wiring board manufacturing industry.

    Science.gov (United States)

    Lam, Carl W; Lim, Seong-Rin; Schoenung, Julie M

    2011-05-15

    Modern manufacturing of printed wiring boards (PWBs) involves extensive use of various hazardous chemicals in different manufacturing steps such as board preparation, circuit design transfer, etching and plating processes. Two complementary environmental screening methods developed by the U.S. EPA, namely: (i) the Tool for the Reduction and Assessment of Chemical and Other Environmental Impacts (TRACI) and (ii) Risk-Screening Environmental Indicators (RSEI), are used to quantify geographic and chemical environmental impacts in the U.S. PWB manufacturing industry based on Toxics Release Inventory (TRI) data. Although the release weight percentages of industrial chemicals such as methanol, glycol ethers and dimethylformamide comprise the larger fraction of reported air and water emissions, results indicate that lead, copper and their compounds' releases correspond to the highest environmental impact from toxicity potentials and risk-screening scores. Combining these results with further knowledge of PWB manufacturing, select alternative chemical processes and materials for pollution prevention are discussed. Examples of effective pollution prevention options in the PWB industry include spent etchant recovery technologies, and process and material substitutions. In addition, geographic assessment of environmental burden highlights states where promotion of pollution prevention strategies and emissions regulations can have the greatest effect to curb the PWB industry's toxic release impacts. Copyright © 2011 Elsevier B.V. All rights reserved.

  5. Risk management in crop production based on the regional index

    Directory of Open Access Journals (Sweden)

    Kokot Željko

    2017-01-01

    Full Text Available Regional index insurance is one of the newer instruments for reducing losses in crop production. The regional index indicates the average yield or average production value in a region, representing the basis for the premium calculation and insurance benefits. The main advantage of this insurance model is that it does not require the damage assessment, which is one of major problems in the relationship between the insured and insurer. In the case of corn, wheat and sunflower production as the most important crops in the region of Ada municipality, the authors describe the methodology of application of the analysed insurance system. Implementation of this contemporary form of insurance in Serbia would reduce the negative financial consequences in agricultural production. The abovementioned model of insurance can be seen as a significant alternative to conventional insurance, which can increase insured area and number of insured, and trust and confidence in insurance companies would also be restored.

  6. Analysing Production Technology and Risk in Organic and Conventional Dutch Arable Farming using Panel Data

    NARCIS (Netherlands)

    Gardebroek, C.; Chavez Clemente, M.D.; Oude Lansink, A.G.J.M.

    2010-01-01

    Abstract This paper compares the production technology and production risk of organic and conventional arable farms in the Netherlands. Just–Pope production functions that explicitly account for output variability are estimated using panel data of Dutch organic and conventional farms. Prior

  7. Adolescent Boys' Grooming Product Use and Perceived Health Risks: An Exploration of Parental Influence

    Science.gov (United States)

    Yoo, Jeong-Ju; Jacob, John; Baier, Margaret

    2012-01-01

    Objective: To investigate parental influence on adolescent boys' use and risk-perceptions of using appearance-related products. Design: Using appearance-enhancing products can present a health threat to adolescents, as these products are not only applied to the body, but can also be ingested. Adolescents may look to their parents for information…

  8. Emerging sustainable/green cleaning products: health and environmental risks

    OpenAIRE

    Aydin, Mehmet Cihan; Işik, Ercan; Ulu, Ali Emre

    2016-01-01

    Sustainable development aims to bring a new perspective to our lives without compromising customer needs and quality. Along with sustainable development many innovative solutions came out. One of them is sustainable green cleaning products and techniques. Today, emissions from conventional cleaning products may cause severe health and environmental issues. Especially sick building syndromes such as eye, skin and respiratory irritations are main health effects of them. They may also contrib...

  9. Key Challenges and Opportunities Associated with the Use of In Vitro Models to Detect Human DILI: Integrated Risk Assessment and Mitigation Plans

    Directory of Open Access Journals (Sweden)

    Franck A. Atienzar

    2016-01-01

    Full Text Available Drug-induced liver injury (DILI is a major cause of late-stage clinical drug attrition, market withdrawal, black-box warnings, and acute liver failure. Consequently, it has been an area of focus for toxicologists and clinicians for several decades. In spite of considerable efforts, limited improvements in DILI prediction have been made and efforts to improve existing preclinical models or develop new test systems remain a high priority. While prediction of intrinsic DILI has improved, identifying compounds with a risk for idiosyncratic DILI (iDILI remains extremely challenging because of the lack of a clear mechanistic understanding and the multifactorial pathogenesis of idiosyncratic drug reactions. Well-defined clinical diagnostic criteria and risk factors are also missing. This paper summarizes key data interpretation challenges, practical considerations, model limitations, and the need for an integrated risk assessment. As demonstrated through selected initiatives to address other types of toxicities, opportunities exist however for improvement, especially through better concerted efforts at harmonization of current, emerging and novel in vitro systems or through the establishment of strategies for implementation of preclinical DILI models across the pharmaceutical industry. Perspectives on the incorporation of newer technologies and the value of precompetitive consortia to identify useful practices are also discussed.

  10. When ‘Feeling Good’ is not Good Enough : Seven Key Opportunities for Emotional Granularity in Product Development

    NARCIS (Netherlands)

    Yoon, J; Pohlmeyer, A.E.; Desmet, P.M.A.

    2016-01-01

    This paper reports a study that explored the usefulness of positive emotional granularity (PEG) in the product development process. PEG
    reflects the ability to interpret and represent the experience of positive emotions with precision and specificity. Interviews were conducted
    with

  11. Food and Beverage Production. Food and Beverage Management Module. Operational Management Programme. Increasing Opportunities for Supervisors and Managers.

    Science.gov (United States)

    Jones, Peter

    This self-instructional unit for supervisors and managers in the British hotel and catering industry is intended to consolidate work covered in a 1-day course. The document begins with an introduction and advice on how to use the unit. The following topics are covered in the unit: (1) planning the menu; (2) food production systems; (3) kitchen…

  12. Dietary risk ranking for residual antibiotics in cultured aquatic products around Tai Lake, China.

    Science.gov (United States)

    Song, Chao; Li, Le; Zhang, Cong; Qiu, Liping; Fan, Limin; Wu, Wei; Meng, Shunlong; Hu, Gengdong; Chen, Jiazhang; Liu, Ying; Mao, Aimin

    2017-10-01

    Antibiotics are widely used in aquaculture and therefore may be present as a dietary risk in cultured aquatic products. Using the Tai Lake Basin as a study area, we assessed the presence of 15 antibiotics in 5 widely cultured aquatic species using a newly developed dietary risk ranking approach. By assigning scores to each factor involved in the ranking matrices, the scores of dietary risks per antibiotic and per aquatic species were calculated. The results indicated that fluoroquinolone antibiotics posed the highest dietary risk in all aquatic species. Then, the total scores per aquatic species were summed by all 15 antibiotic scores of antibiotics, it was found that Crab (Eriocheir sinensis) had the highest dietary risks. Finally, the most concerned antibiotic category and aquatic species were selected. This study highlighted the importance of dietary risk ranking in the production and consumption of cultured aquatic products around Tai Lake. Copyright © 2017 Elsevier Inc. All rights reserved.

  13. Time-explicit methods for joint economical and geological risk mitigation in production optimization

    DEFF Research Database (Denmark)

    Christiansen, Lasse Hjuler; Capolei, Andrea; Jørgensen, John Bagterp

    2016-01-01

    Real-life applications of production optimization face challenges of risks related to unpredictable fluctuations in oil prices and sparse geological data. Consequently, operating companies are reluctant to adopt model-based production optimization into their operations. Conventional production...... of mitigating economical and geological risks. As opposed to conventional strategies that focus on a single long-term objective, TE methods seek to reduce risks and promote returns over the entire reservoir life by optimization of a given ensemble-based geological risk measure over time. By explicit involvement...... of time, economical risks are implicitly addressed by balancing short-term and long-term objectives throughout the reservoir life. Open-loop simulations of a two-phase synthetic reservoir demonstrate that TE methods may significantly improve short-term risk measures such as expected return, standard...

  14. Opportunities for New Insights on the Life-Course Risks and Outcomes of Cognitive Decline in the Kavli HUMAN Project.

    Science.gov (United States)

    Langa, Kenneth M; Cutler, David

    2015-09-01

    The Kavli HUMAN Project (KHP) will provide groundbreaking insights into how biological, medical, and social factors interact and impact the risks for cognitive decline from birth through older age. It will richly measure the effect of cognitive decline on the ability to perform key activities of daily living. In addition, due to its family focus, the KHP will measure the impact on family members, including the amount of time that family members spend providing care to older adults with dementia. It will also clarify the division of caregiving duties among family members and the effects on caregivers' work, family life, and balance thereof. At the same time, for care that the family cannot provide, it will clarify the extent to which cognitive decline impacts healthcare utilization and end-of-life decision making.

  15. Identification and Risk Treatment in Launching a New Product in the Aerospace Market

    Directory of Open Access Journals (Sweden)

    Vivian Eugenia da Matta

    2015-08-01

    Full Text Available The launch of new products resulted from investments in research and development and the need for them markets makes risk management is an important practice within companies in order to reduce the negative risks generated in the release process. The purpose of this article is to carry out studies to identify the risks involved in launching new products and forms of treatment used by the organization to deal with these risks. For this we conducted a case study in a Brazilian company that operates in the aerospace market. Information was collected through semi-structured interviews with three managers of the company. The risks identified and strategies for treating these risks have been organized into tables where risks identified for staff involved are presented. The results of the study showed that the risk management, in fact, contributes to the reduction of the negative risks that may adversely affect the process of launching new products in the market. The study identified some findings, such as the aerospace market shares for the sale of its products occur mainly in the phase prior to the production and delivery of these. The identified risks are generated by the interaction between the company and those involved in the supply chain, one of the ways of treating risk used by the company is to maintain the same relationship network, in addition to establishing rules of conduct for the supply chain. The release of new products does not occur through mass media face, since there is a specific, small market segment that has the means to buy the products. Study limitations stem from the inability to generalize the results depending on the method used and the interviews only to company officials.

  16. A systematic review of internet-based worksite wellness approaches for cardiovascular disease risk management: outcomes, challenges & opportunities.

    Science.gov (United States)

    Aneni, Ehimen C; Roberson, Lara L; Maziak, Wasim; Agatston, Arthur S; Feldman, Theodore; Rouseff, Maribeth; Tran, Thinh H; Blumenthal, Roger S; Blaha, Michael J; Blankstein, Ron; Al-Mallah, Mouaz H; Budoff, Matthew J; Nasir, Khurram

    2014-01-01

    The internet is gaining popularity as a means of delivering employee-based cardiovascular (CV) wellness interventions though little is known about the cardiovascular health outcomes of these programs. In this review, we examined the effectiveness of internet-based employee cardiovascular wellness and prevention programs. We conducted a systematic review by searching PubMed, Web of Science and Cochrane library for all published studies on internet-based programs aimed at improving CV health among employees up to November 2012. We grouped the outcomes according to the American Heart Association (AHA) indicators of cardiovascular wellbeing--weight, BP, lipids, smoking, physical activity, diet, and blood glucose. A total of 18 randomized trials and 11 follow-up studies met our inclusion/exclusion criteria. Follow-up duration ranged from 6-24 months. There were significant differences in intervention types and number of components in each intervention. Modest improvements were observed in more than half of the studies with weight related outcomes while no improvement was seen in virtually all the studies with physical activity outcome. In general, internet-based programs were more successful if the interventions also included some physical contact and environmental modification, and if they were targeted at specific disease entities such as hypertension. Only a few of the studies were conducted in persons at-risk for CVD, none in blue-collar workers or low-income earners. Internet based programs hold promise for improving the cardiovascular wellness among employees however much work is required to fully understand its utility and long term impact especially in special/at-risk populations.

  17. A systematic review of internet-based worksite wellness approaches for cardiovascular disease risk management: outcomes, challenges & opportunities.

    Directory of Open Access Journals (Sweden)

    Ehimen C Aneni

    Full Text Available CONTEXT: The internet is gaining popularity as a means of delivering employee-based cardiovascular (CV wellness interventions though little is known about the cardiovascular health outcomes of these programs. In this review, we examined the effectiveness of internet-based employee cardiovascular wellness and prevention programs. EVIDENCE ACQUISITION: We conducted a systematic review by searching PubMed, Web of Science and Cochrane library for all published studies on internet-based programs aimed at improving CV health among employees up to November 2012. We grouped the outcomes according to the American Heart Association (AHA indicators of cardiovascular wellbeing--weight, BP, lipids, smoking, physical activity, diet, and blood glucose. EVIDENCE SYNTHESIS: A total of 18 randomized trials and 11 follow-up studies met our inclusion/exclusion criteria. Follow-up duration ranged from 6-24 months. There were significant differences in intervention types and number of components in each intervention. Modest improvements were observed in more than half of the studies with weight related outcomes while no improvement was seen in virtually all the studies with physical activity outcome. In general, internet-based programs were more successful if the interventions also included some physical contact and environmental modification, and if they were targeted at specific disease entities such as hypertension. Only a few of the studies were conducted in persons at-risk for CVD, none in blue-collar workers or low-income earners. CONCLUSION: Internet based programs hold promise for improving the cardiovascular wellness among employees however much work is required to fully understand its utility and long term impact especially in special/at-risk populations.

  18. Challenges and Opportunities in the Use of Marketing Tools and the Promotion of Non Wood Forest Products-Based Small and Medium Enterprises in the South East Europe

    Directory of Open Access Journals (Sweden)

    Makedonka Stojanovska

    2015-06-01

    Full Text Available Background and Purpose: The South-east Europe (SEE region is facing a new market economy era where establishing new businesses is more than needed in all sectors. The forest sector, faced with new market emerging opportunities, is affected by the constant increase of a number of forest related enterprises. This paper describes the challenges and opportunities related to the use of marketing tools for improving business of the small and medium enterprises (SMEs dealing with non-wood forest products (NWFPs in SEE region. The research on this subject in the SEE region is scarce despite the rich biodiversity as a solid base for establishing eco-businesses. Materials and Methods: The method used in this paper is quantitative, based on survey data collected from enterprises in the NWFPs sector followed by statistical data analyses using Statistical Package for Social Sciences (SPSS. The survey was conducted during 2011 and 2012 in four SEE countries: Croatia, Bosnia and Herzegovina, Serbia and Macedonia. Results: The results showed that developed channels of distribution, branding and advertising of NWFPs are recognized in all countries as important and very important, but these marketing tools are used only few times per year. The majority of respondents pointed out advertising as the most frequently used and as the most successful tool. Interviewees’ future investments are to be focused on improving equipment for drying, packing, refrigerating and transport. Several entrepreneurs from Macedonia pointed out that they would invest in increasing the number of buying points and herb plantations while almost all Croatian entrepreneurs will invest in advertising, branding and promotion. Majority of respondents from Serbia are also of the opinion that financial resources should be invested in new equipment. The reasons for these investments can be summarized in reducing costs and increasing profit or in faster turnover. Conclusions: The use of marketing

  19. Analyzing Integrated Cost-Schedule Risk for Complex Product Systems R&D Projects

    Directory of Open Access Journals (Sweden)

    Zhe Xu

    2014-01-01

    Full Text Available The vast majority of the research efforts in project risk management tend to assess cost risk and schedule risk independently. However, project cost and time are related in reality and the relationship between them should be analyzed directly. We propose an integrated cost and schedule risk assessment model for complex product systems R&D projects. Graphical evaluation review technique (GERT, Monte Carlo simulation, and probability distribution theory are utilized to establish the model. In addition, statistical analysis and regression analysis techniques are employed to analyze simulation outputs. Finally, a complex product systems R&D project as an example is modeled by the proposed approach and the simulation outputs are analyzed to illustrate the effectiveness of the risk assessment model. It seems that integrating cost and schedule risk assessment can provide more reliable risk estimation results.

  20. Realize a world of opportunity

    International Nuclear Information System (INIS)

    Christie, J.

    2000-01-01

    The Export Development Corporation (EDC) is a federal government-owned financial institution established to support Canadian firms of all sizes in the pursuit of international trade and investment opportunities. EDC is doing business in over 200 countries, worth over $40 billion. Over 5,000 Canadian companies were using EDC products and services in 1999. EDC offers accounts receivable insurance, contract insurance, political risk insurance and various financial products such as direct buyer loans, lines of credit, guarantees for bonds, access to surety services, and limited recourse structured finance. In evaluating a prospective transaction, EDC looks for assurances of the Canadian exporter's capability to deliver as promised, a credit-worthy counter-party, the viability of the project including, when deemed necessary, an environmental review, and benefits to Canada. CDM projects and environmental projects in general are within the mandate of EDC, provided they meet EDC's normal due diligence and analysis requirements

  1. Solar Production of Fuels from Water and CO2: Perspectives and Opportunities for a Sustainable Use of Renewable Energy

    Directory of Open Access Journals (Sweden)

    Passalacqua R.

    2015-09-01

    Full Text Available The increasing energy demand, the depletion of fossil fuels and the concern of maintaining clean environment have become the main reasons for a worldwide attention on renewable energy production. Fuel and energy productions from sunlight represent exciting challenges in the next future thank to the recent developments in related technologies, catalysts and materials. It will be discussed the present economic data concerning energy request, the current technological issues required to face an increase of the use of renewable energy, the main drawbacks related to low conversion efficiency in energy applications, the new routes for producing renewable hydrogen and the bio-mimicking approach provided by artificial leaves. Finally, the critical role of nanoscale engineered processes for the development of efficient and cost-effective systems will be evidenced.

  2. International oil opportunities

    International Nuclear Information System (INIS)

    Hares, T.N.D.; Mann, D.W.

    1995-01-01

    Some of the key issues to be addressed when selecting international opportunities, were discussed. The ideal opportunity should have the following characteristics: (1) large, low risk (2) high percentage of rent available to the investor, (3) low cost and low technical requirements, (4) low country risk, (5) low competition, (6) easy to access, and (7) favorable environment in which to work. Entering an international opportunity can be achieved by competitive bidding, direct negotiation, partnership, corporate and/or asset acquisition, and long-term relationships. Key success factors were identified as (1) applying technical financial and commercial skills in the international environment, (2) speedy response, (3) excellent relationships in the foreign country, (4) understanding the local culture, and (5) keeping a good track record. 6 figs

  3. Optimization of the production process of hybrid and multivalent formulation Bombesin/RGD for the opportune detection of breast cancer

    International Nuclear Information System (INIS)

    Robles M, M.

    2013-01-01

    The radiopharmaceuticals of third generation are used in nuclear medicine to obtain images of specific molecular targets, and they are unique in their capacity to detect in vivo specific biochemical sites as receptors that are over-expressed in diverse illness. In cancer cells several types of receptors are over-expressed, as the integrin s α(v)β(3) and α(v)β(5) that specifically recognize the sequence RGD (Arginine-Glycin-Ac. Aspartic) and gastrin-releasing peptide that recognizes specifically to the peptide Lys 3 -Bombesin. The integrin s α(v)β(3) and α(v)β(5) are involved in the tumor angio genesis processes and the gastrin-releasing peptide is over-expressed in breast and prostate cancer. The molecular recognition of the specific receptors is the basis to be utilized as targets of the radiopharmaceuticals 99m Tc-HYNIC-Bombesin and 99m Tc-HYNIC-RGD. In this work was developed a lyophilized pharmaceutical formulation effective, stable and safe for the simultaneous obtaining of the radiopharmaceuticals 99m Tc-HYNIC-Bombesin ( 99m Tc-EDDA/HYNIC-Lys 3 -Bombesin) and 99m Tc-HYNIC-RGD ( 99m Tc EDDA/HYNIC-E-[c(RGDfK)] 2 ). Later on the production process of the product HYNIC-Bombesin/RGD-Sn was optimized using a factorial design and the formulation was transferred to the production plant of radiopharmaceuticals of the Instituto Nacional de Investigaciones Nucleares (ININ). The optimized formulation is described in the following chart: HYNIC-[Lys 3 ]-Bombesin - 12.5 μg; HYNIC-E-c[RGDfK] 2 - 12.5 μg; Stannous chloride (SnCl 2 ) - 20 μg; Ethylenediamine diacetic acid (EDDA) - 10 mg; N-tris(hydroxymethyl)methyl glycin (Tricine) - 20 mg; Mannitol - 50 mg. The production process was validated and were carried out the stability studies under refrigeration conditions. (Author)

  4. High-resolution techno-ecological modelling of a bioenergy landscape to identify climate mitigation opportunities in cellulosic ethanol production

    Science.gov (United States)

    Field, John L.; Evans, Samuel G.; Marx, Ernie; Easter, Mark; Adler, Paul R.; Dinh, Thai; Willson, Bryan; Paustian, Keith

    2018-03-01

    Although dedicated energy crops will probably be an important feedstock for future cellulosic bioenergy production, it is unknown how they can best be integrated into existing agricultural systems. Here we use the DayCent ecosystem model to simulate various scenarios for growing switchgrass in the heterogeneous landscape that surrounds a commercial-scale cellulosic ethanol biorefinery in southwestern Kansas, and quantify the associated fuel production costs and lifecycle greenhouse gas (GHG) emissions. We show that the GHG footprint of ethanol production can be reduced by up to 22 g of CO2 equivalent per megajoule (CO2e MJ-1) through careful optimization of the soils cultivated and corresponding fertilizer application rates (the US Renewable Fuel Standard requires a 56 gCO2e MJ-1 lifecycle emissions reduction for `cellulosic' biofuels compared with conventional gasoline). This improved climate performance is realizable at modest additional costs, less than the current value of low-carbon fuel incentives. We also demonstrate that existing subsidized switchgrass plantings within this landscape probably achieve suboptimal GHG mitigation, as would landscape designs that strictly minimize the biomass collection radius or target certain marginal lands.

  5. Adaptation in Europe. Addressing risks and opportunities from climate change in the context of socio-economic developments

    Energy Technology Data Exchange (ETDEWEB)

    Isoard, S. [EEA (Denmark); Winograd, M. [Alterra (Netherlands)

    2013-04-15

    The 'Adaptation in Europe' report describes the policies and some of the measures taken at EU level and by European countries. So far half of the 32 EEA member countries have plans for adaptation, and some have started to take action, although all countries still have a lot of work to do. While global mitigation efforts should continue to aim to limit global temperature increases to 2 deg. C, the report states that it is necessary to prepare for a greater range of temperature increases and other climate changes. This is needed to properly account for the many uncertainties in climatic and socio-economic projections. The report recommends a combination of different measures - 'grey' measures such as technological and engineering projects, 'green' ecosystem-based approaches using nature, and so-called 'soft' measures such as policies to change governance approaches. The most effective adaptation projects often combine two or more different approaches, the report says. For example, adaptation on France's Mediterranean coast uses an integrated approach considering climate change, tourism, transport and biodiversity. In urban areas green spaces and water bodies work together with building design to reduce heatwave risks. Barcelona has also started to adapt to water shortages with a new highly efficient desalination plant. This 'grey' project works in tandem with other 'soft' initiatives such as incentives to reduce water consumption, reducing the impacts from prolonged droughts. While the cost of adaptation may be high in some cases, the report emphasises the overall savings from some adaptation actions. One of the largest ecosystem-based adaptation projects is restoring the Danube river basin to its previously natural state. Although it will cost an estimated Euro 183 million, it should help prevent flooding such as the 2005 event which alone cost Euro 396 million in damages. Early warning systems to help

  6. Adaptation in Europe. Addressing risks and opportunities from climate change in the context of socio-economic developments

    Energy Technology Data Exchange (ETDEWEB)

    Isoard, S. [EEA (Denmark); Winograd, M. [Alterra (Netherlands)

    2013-04-15

    The 'Adaptation in Europe' report describes the policies and some of the measures taken at EU level and by European countries. So far half of the 32 EEA member countries have plans for adaptation, and some have started to take action, although all countries still have a lot of work to do. While global mitigation efforts should continue to aim to limit global temperature increases to 2 deg. C, the report states that it is necessary to prepare for a greater range of temperature increases and other climate changes. This is needed to properly account for the many uncertainties in climatic and socio-economic projections. The report recommends a combination of different measures - 'grey' measures such as technological and engineering projects, 'green' ecosystem-based approaches using nature, and so-called 'soft' measures such as policies to change governance approaches. The most effective adaptation projects often combine two or more different approaches, the report says. For example, adaptation on France's Mediterranean coast uses an integrated approach considering climate change, tourism, transport and biodiversity. In urban areas green spaces and water bodies work together with building design to reduce heatwave risks. Barcelona has also started to adapt to water shortages with a new highly efficient desalination plant. This 'grey' project works in tandem with other 'soft' initiatives such as incentives to reduce water consumption, reducing the impacts from prolonged droughts. While the cost of adaptation may be high in some cases, the report emphasises the overall savings from some adaptation actions. One of the largest ecosystem-based adaptation projects is restoring the Danube river basin to its previously natural state. Although it will cost an estimated Euro 183 million, it should help prevent flooding such as the 2005 event which alone cost Euro 396 million in damages. Early warning systems to help predict forest fires, floods and droughts have been set up in

  7. When companies produce their own energy. Opportunities and risks; Wenn Unternehmen ihre Energie selbst erzeugen. Chancen und Risiken

    Energy Technology Data Exchange (ETDEWEB)

    Hergass, Andreas [Ensys AG, Frankfurt am Main (Germany)

    2013-05-15

    More and more companies are considering the option of electricity self-supply. According to a survey conducted by the German Chamber of Industry and Commerce, 5% of all German companies have already taken the step of becoming a self-supplier and another 10% are contemplating it. However investments to this end must be planned with precision. In many cases they fail to pay off because the costs of procurement, operation and maintenance of power production plants stand in direct competition with the prices that energy trading companies can achieve in the electricity market. For companies that have committed themselves to the principles of sustainability and ecology in their corporate philosophy, having their own electricity supply will be important regardless of its profitability. In any case however they will have a requirement for partners to help ensure that internal and external energy supply systems are optimally integrated with each other.

  8. Weather based risks and insurances for agricultural production

    Science.gov (United States)

    Gobin, Anne

    2015-04-01

    Extreme weather events such as frost, drought, heat waves and rain storms can have devastating effects on cropping systems. According to both the agriculture and finance sectors, a risk assessment of extreme weather events and their impact on cropping systems is needed. The principle of return periods or frequencies of natural hazards is adopted in many countries as the basis of eligibility for the compensation of associated losses. For adequate risk management and eligibility, hazard maps for events with a 20-year return period are often used. Damages due to extreme events are strongly dependent on crop type, crop stage, soil type and soil conditions. The impact of extreme weather events particularly during the sensitive periods of the farming calendar therefore requires a modelling approach to capture the mixture of non-linear interactions between the crop, its environment and the occurrence of the meteorological event in the farming calendar. Physically based crop models such as REGCROP (Gobin, 2010) assist in understanding the links between different factors causing crop damage. Subsequent examination of the frequency, magnitude and impacts of frost, drought, heat stress and soil moisture stress in relation to the cropping season and crop sensitive stages allows for risk profiles to be confronted with yields, yield losses and insurance claims. The methodology is demonstrated for arable food crops, bio-energy crops and fruit. The perspective of rising risk-exposure is exacerbated further by limited aid received for agricultural damage, an overall reduction of direct income support to farmers and projected intensification of weather extremes with climate change. Though average yields have risen continuously due to technological advances, there is no evidence that relative tolerance to adverse weather events has improved. The research is funded by the Belgian Science Policy Organisation (Belspo) under contract nr SD/RI/03A.

  9. DNA Repair Alterations in Children With Pediatric Malignancies: Novel Opportunities to Identify Patients at Risk for High-Grade Toxicities

    International Nuclear Information System (INIS)

    Ruebe, Claudia E.; Fricke, Andreas; Schneider, Ruth; Simon, Karin; Kuehne, Martin; Fleckenstein, Jochen; Graeber, Stefan; Graf, Norbert; Ruebe, Christian

    2010-01-01

    Purpose: To evaluate, in a pilot study, the phosphorylated H2AX (γH2AX) foci approach for identifying patients with double-strand break (DSB) repair deficiencies, who may overreact to DNA-damaging cancer therapy. Methods and Materials: The DSB repair capacity of children with solid cancers was analyzed compared with that of age-matched control children and correlated with treatment-related normal-tissue responses (n = 47). Double-strand break repair was investigated by counting γH2AX foci in blood lymphocytes at defined time points after irradiation of blood samples. Results: Whereas all healthy control children exhibited proficient DSB repair, 3 children with tumors revealed clearly impaired DSB repair capacities, and 2 of these repair-deficient children developed life-threatening or even lethal normal-tissue toxicities. The underlying mutations affecting regulatory factors involved in DNA repair pathways were identified. Moreover, significant differences in mean DSB repair capacity were observed between children with tumors and control children, suggesting that childhood cancer is based on genetic alterations affecting DSB repair function. Conclusions: Double-strand break repair alteration in children may predispose to cancer formation and may affect children's susceptibility to normal-tissue toxicities. Phosphorylated H2AX analysis of blood samples allows one to detect DSB repair deficiencies and thus enables identification of children at risk for high-grade toxicities.

  10. Equal Opportunities Questionnaire

    CERN Multimedia

    2007-01-01

    The initiative to promote Equal Opportunities at CERN started in 1993. The first Equal Opportunities Officer was appointed in 1996, which was followed by the creation of the Equal Opportunities Advisory Panel in 1998. Initially the concern was mainly the fair treatment of women in the work-place. Today the emphasis has evolved to ensuring that diversity is used to increase creativity and productivity in the work-place. In order to ensure that all aspects of Equal Opportunities and Diversity are covered, CERN’s Equal Opportunities team has prepared a survey to obtain your input. Your answers are confidential and will only be used for generating statistics. The questionnaire is on-line and can be accessed via: https://espace.cern.ch/EOQ. We hope that you will take a few minutes of your time to give your input and would be grateful if you could reply before 15/10/07. For further information about Equal Opportunities at CERN see: http://cern.ch/equal-opportunities The Equa...

  11. Equal Opportunities Questionnaire

    CERN Multimedia

    2007-01-01

    The initiative to promote Equal Opportunities at CERN started in 1993. The first Equal Opportunities Officer was appointed in 1996 followed by the creation of the Equal Opportunities Advisory Panel in 1998. Initially the concern was mainly the fair treatment of women in the work-place. Today the emphasis has evolved to ensuring that diversity is used to increase creativity and productivity in the work-place. In order to ensure that all aspects of Equal Opportunities and Diversity are covered, CERN’s Equal Opportunities team has prepared a survey to obtain your input. Your answers are confidential and will only be used for generating statistics. The questionnaire is on-line and can be accessed via: https://espace.cern.ch/EOQ. We hope that you will take a few minutes of your time to give your input and would be grateful if you could reply before 15/10/07. For further information about Equal Opportunities at CERN see: http://cern.ch/equal-opportunities The Equal Opportuni...

  12. [Hygienic evaluation of risk factors on powder metallurgy production].

    Science.gov (United States)

    2011-01-01

    Complex hygienic, clinical, sociologic and epidemiologic studies revealed reliable relationship between work conditions and arterial hypertension, locomotory system disorders, monocytosis in powder metallurgy production workers. Findings are more probable cardiovascular and respiratory diseases, digestive tract diseases due to influence of lifestyle factors.

  13. Weather based risks and insurances for crop production in Belgium

    Science.gov (United States)

    Gobin, Anne

    2014-05-01

    Extreme weather events such as late frosts, droughts, heat waves and rain storms can have devastating effects on cropping systems. Damages due to extreme events are strongly dependent on crop type, crop stage, soil type and soil conditions. The perspective of rising risk-exposure is exacerbated further by limited aid received for agricultural damage, an overall reduction of direct income support to farmers and projected intensification of weather extremes with climate change. According to both the agriculture and finance sectors, a risk assessment of extreme weather events and their impact on cropping systems is needed. The impact of extreme weather events particularly during the sensitive periods of the farming calendar requires a modelling approach to capture the mixture of non-linear interactions between the crop, its environment and the occurrence of the meteorological event. The risk of soil moisture deficit increases towards harvesting, such that drought stress occurs in spring and summer. Conversely, waterlogging occurs mostly during early spring and autumn. Risks of temperature stress appear during winter and spring for chilling and during summer for heat. Since crop development is driven by thermal time and photoperiod, the regional crop model REGCROP (Gobin, 2010) enabled to examine the likely frequency, magnitude and impacts of frost, drought, heat stress and waterlogging in relation to the cropping season and crop sensitive stages. The risk profiles were subsequently confronted with yields, yield losses and insurance claims for different crops. Physically based crop models such as REGCROP assist in understanding the links between different factors causing crop damage as demonstrated for cropping systems in Belgium. Extreme weather events have already precipitated contraction of insurance coverage in some markets (e.g. hail insurance), and the process can be expected to continue if the losses or damages from such events increase in the future. Climate

  14. Patient awareness of stent type, risk of cardiac events, and symptoms of myocardial infarction among PCI patients: a missed educational opportunity?

    Science.gov (United States)

    D'Elia, Alexis A; Hafiz, Abdul Moiz; Naidu, Srihari S; Marzo, Kevin P

    2011-04-01

     Timely and successful treatment of myocardial infarction (MI) requires accurate recognition by the patient of the signs and symptoms. As patients who have undergone percutaneous coronary intervention (PCI) remain at risk for cardiac events, it is important that they have a basic understanding of their cardiac status.  We surveyed 80 consecutive patients following elective PCI using a simple multiple-choice questionnaire. Type of stent (bare metal or drug-eluting), how they perceive the procedure would affect their cardiovascular health, their perceived risk of a future MI, and whether they recalled specific education on how to recognize symptoms of an MI were queried.  45% (n = 36) of patients were unaware of stent type. 10% stated PCI was performed to relieve symptoms of angina, 30% (n = 24) stated it would prevent MI, 56.3% (n = 45) stated that it would both prevent MI and reduce symptoms of angina, while 3.8% stated it would do neither. 86.3% (n = 69) stated they remained at risk for MI despite the procedure. However, 42.5% (n = 34) of patients did not perceive to have received specific education on the signs and symptoms of MI during their hospital stay.  Patient understanding of stent type, expected cardiovascular outcomes, and recognition of MI post-PCI appears low in the real-world setting. A systematic approach to post-PCI education should be incorporated into routine care, in order to capitalize on the educational opportunity afforded by this high risk population. ©2010, Wiley Periodicals, Inc.

  15. The Prison Economy of Needles and Syringes: What Opportunities Exist for Blood Borne Virus Risk Reduction When Prices Are so High?

    Directory of Open Access Journals (Sweden)

    Carla Treloar

    Full Text Available A formal Needle and Syringe Program (NSP is not provided in Australian prisons. Injecting equipment circulates in prisons as part of an informal and illegal economy. This paper examined how this economy generates blood-borne virus (BBV risk and risk mitigation opportunities for inmates.The HITS-p cohort recruited New South Wales inmates who had reported ever injecting drugs and who had a negative HCV serological test within 12 months prior to enrolment. For this study, qualitative interviews were conducted with 30 participants enrolled in HITS-p. Participants included 10 women and were incarcerated in 12 prisons.A needle/syringe was nominated as being typically priced in the 'inside' prison economy at $100-$150, with a range of $50-$350. Purchase or hire of equipment was paid for in cash (including transactions that occurred outside prison and in exchange for drugs and other commodities. A range of other resources was required to enable successful needle/syringe economies, especially relationships with visitors and other prisoners, and violence to ensure payment of debts. Strategies to mitigate BBV risk included retaining one needle/syringe for personal use while hiring out others, keeping drug use (and ownership of equipment "quiet", stealing used equipment from the prison health clinic, and manufacture of syringes from other items available in the prison.The provision of prison NSP would disrupt the inside economies built around contraband needles/syringes, as well as minimise BBV risk. However, any model of prison NSP should be interrogated for any unanticipated markets that could be generated as a result of its regulatory practices.

  16. The Prison Economy of Needles and Syringes: What Opportunities Exist for Blood Borne Virus Risk Reduction When Prices Are so High?

    Science.gov (United States)

    Treloar, Carla; McCredie, Luke; Lloyd, Andrew R

    2016-01-01

    A formal Needle and Syringe Program (NSP) is not provided in Australian prisons. Injecting equipment circulates in prisons as part of an informal and illegal economy. This paper examined how this economy generates blood-borne virus (BBV) risk and risk mitigation opportunities for inmates. The HITS-p cohort recruited New South Wales inmates who had reported ever injecting drugs and who had a negative HCV serological test within 12 months prior to enrolment. For this study, qualitative interviews were conducted with 30 participants enrolled in HITS-p. Participants included 10 women and were incarcerated in 12 prisons. A needle/syringe was nominated as being typically priced in the 'inside' prison economy at $100-$150, with a range of $50-$350. Purchase or hire of equipment was paid for in cash (including transactions that occurred outside prison) and in exchange for drugs and other commodities. A range of other resources was required to enable successful needle/syringe economies, especially relationships with visitors and other prisoners, and violence to ensure payment of debts. Strategies to mitigate BBV risk included retaining one needle/syringe for personal use while hiring out others, keeping drug use (and ownership of equipment) "quiet", stealing used equipment from the prison health clinic, and manufacture of syringes from other items available in the prison. The provision of prison NSP would disrupt the inside economies built around contraband needles/syringes, as well as minimise BBV risk. However, any model of prison NSP should be interrogated for any unanticipated markets that could be generated as a result of its regulatory practices.

  17. Developing Blue Ocean Strategy of Sustainable Product Design and Development for Business Opportunities of BOP Groups in Taiwan

    Directory of Open Access Journals (Sweden)

    Jui-Che Tu

    2014-01-01

    Full Text Available This study expands the definition of the poor group and attempts to delve into and make known the phenomenon of poverty in Taiwan and aims to explore the goals and possibilities of the BOP consumer market. Through a questionnaire survey and expert interviews, this research adopts the concept of sustainability to discuss the lifestyle and consumption characteristics of the BOP group and establishes a design strategic norm of the sustainable products. The findings show that the BOP group in Taiwan is new poverty or working poor and high quality and common prices are the main requirements; these should be introduced into the development model of sustainable design.

  18. Opportunities and challenges for smallholder pig production systems in a mountainous region of Xishuangbanna, Yunnan Province, China

    OpenAIRE

    Riedel, Simon; Schiborra, Anne; Huelsebusch, Christian; Huanming, Mao; Schlecht, Eva

    2012-01-01

    China’s small-scale pig keepers are the largest community of pork producers worldwide. About 56 % of the world's pigs originate from such systems, each producing 2–5 head per year. This study analyzes pig smallholders in Xishuangbanna, a prefecture of Yunnan Province. Categorical principal component analysis and two-step cluster analysis were used to identify three main production systems: livestock-corn-based (LB; 41 %), rubber based (RB; 39 %), and pig based (PB; 20 %) systems. RB farms ear...

  19. Opportunities in biotechnology.

    Science.gov (United States)

    Gartland, Kevan M A; Gartland, Jill S

    2018-06-08

    Strategies for biotechnology must take account of opportunities for research, innovation and business growth. At a regional level, public-private collaborations provide potential for such growth and the creation of centres of excellence. By considering recent progress in areas such as genomics, healthcare diagnostics, synthetic biology, gene editing and bio-digital technologies, opportunities for smart, strategic and specialised investment are discussed. These opportunities often involve convergent or disruptive technologies, combining for example elements of pharma-science, molecular biology, bioinformatics and novel device development to enhance biotechnology and the life sciences. Analytical applications use novel devices in mobile health, predictive diagnostics and stratified medicine. Synthetic biology provides opportunities for new product development and increased efficiency for existing processes. Successful centres of excellence should promote public-private business partnerships, clustering and global collaborations based on excellence, smart strategies and innovation if they are to remain sustainable in the longer term. Copyright © 2018. Published by Elsevier B.V.

  20. A call for conservation scientists to evaluate opportunities and risks from operation of vertical axis wind turbines

    Science.gov (United States)

    Santangeli, Andrea; Katzner, Todd E.

    2015-01-01

    A new conservation paradigm (Kareiva and Marvier, 2012) emphasizes the need for scientists to embrace a holistic approach taking into account the social and natural dimensions of conservation in human-dominated landscapes. While there is heavy debate over the new approach (Tallis and Lubchenco, 2014), most conservation scientists seem to agree on to the need to cooperate with corporations when such interaction can benefit people and the environment (Miller et al., 2014;Tallis and Lubchenco, 2014). Cooperation can be most productive when established in the early phases of development, but this requires a high capacity for forward looking pre-emptive action (i.e., anticipating potential forthcoming issues before they arise; Sutherland and Woodroof, 2009). This framework is particularly salient for rapidly developing and expanding technologies such as those for harvesting renewable energy sources. Here the stakes are very high, as they concern mitigating negative consequences to global climate while generating energy without impacting wildlife. In this vein, past experience is instructional. The environmental impacts of biofuels and wind, among others, have been identified and evaluated rather late (Sutherland and Woodroof, 2009), so that implementation of best management practices on existing facilities is now often prohibitively expensive.

  1. Opportunities and challenges for smallholder pig production systems in a mountainous region of Xishuangbanna, Yunnan Province, China.

    Science.gov (United States)

    Riedel, Simon; Schiborra, Anne; Huelsebusch, Christian; Huanming, Mao; Schlecht, Eva

    2012-12-01

    China's small-scale pig keepers are the largest community of pork producers worldwide. About 56 % of the world's pigs originate from such systems, each producing 2-5 head per year. This study analyzes pig smallholders in Xishuangbanna, a prefecture of Yunnan Province. Categorical principal component analysis and two-step cluster analysis were used to identify three main production systems: livestock-corn-based (LB; 41 %), rubber based (RB; 39 %), and pig based (PB; 20 %) systems. RB farms earn high income from rubber and fatten cross-bred pigs, often using purchased feeds. PB farms own similar-sized rubber plantations and raise pigs, with fodder mainly being cultivated and collected in the forest. LB farms grow corn, rice, and tea while also raising pigs, fed with collected and cultivated fodder as well. About one third of pigs were marketed (LB, 20 %; RB, 42 %; PB, 25 %), and local pig meat is highly appreciated in the nearby town. High mortality, low reproductive performance, and widespread malnourishment are the systems' main constraints. Basic training in hygiene and reproduction management could significantly increase production; most effective measures would be counterbalancing seasonal malnourishment and exploration of locally available protein feeds. Through support by external expertise, farmers could more effectively trade their pigs at lucrative town markets.

  2. RISKS ASSOCIATED WITH INVESTMENTS IN STRUCTURED INVESTMENT PRODUCTS, SELECTION CRITERIA OF SIP`S

    Directory of Open Access Journals (Sweden)

    Ignatyuk Aleksandr Sergeevich

    2013-05-01

    Full Text Available Purpose To identify and classify the major risks affecting on the structured investment products, to submit proposals to limit their impact. Methodology The work is based on a studying of the practice of investments in structured investment products, detection and investigation of sources of market risk of structured investment products. Results Structured investment products, as any other investment product, has a significant set of risks that could affect to a large extent on its evaluation and determine the behavior of the investor. Financial engineers have the ability to control most of these risks, as well as to limit their impact. Thus, the structured investment product, unlike most classic investment instruments can provide investors with highly transparent mechanism to determining the ratio of investment risk and potential income. Practical implications The results can be used in a scientific investigation of the phenomenon of structured investment products, as well as practical work on the formation of the structured products by investment banks and brokerage firms.

  3. Buying Behavior Of Organic Vegetables Product The Effects Of Perceptions Of Quality And Risk

    Directory of Open Access Journals (Sweden)

    Doni Purnama Alamsyah

    2015-08-01

    Full Text Available Abstract Consumer behaviors are more important in the study of Green Marketing. This studied aims to examined buying behavior of consumers on organic products which is formed by perception of quality and perception of risk. The research model with three hypotheses to explained the relationship and influenced between the constructs that perception of quality perception of risk and purchase decision. In these empirical studied treated 366 respondents from customer of retail supermarkets in West Java - Indonesia. Results of research founded a significant negative relationship between perception of quality and perception of risk. As well as the behavior of perception of quality and the perception of risk has a significant influenced on purchase decision. Retail self-service needs to improve the perception of quality and reduces the risk perception of the consumers if purchasing behavior of consumers want increase on organic products. This studied was useful in raising awareness of self-service retail and consumers for environmentally friendly products.

  4. Incorporating Risks in Economic Values for Pigs in Smallholder Production Systems in Kenya

    DEFF Research Database (Denmark)

    Mbuthias, Jackson; Rewe, Thomas; Okeno, Tobias

    production systems in Kenya. In addition to traditional bio-economic profit model, a risk-rated model was used to derive risk-rated economic values. This model accounted for imperfect knowledge concerning risk attitude of farmers and variance of input and output prices. Positive economic values obtained...... for traits DP, LWg, LWs, PoSR, PrSR, SoSR and TNB indicate that targeting them in improvement would positively impact profitability in pig breeding programmes. Accounting for risks in the EVs did not yield errors greater than ±50%. Therefore both traditional and risk-rated models can be satisfactorily used...

  5. The effect of price and production risks on optimal farm plans in Swiss dairy production considering 2 different milk quota systems.

    Science.gov (United States)

    Briner, S; Finger, R

    2013-04-01

    The amount of milk produced on Swiss dairy farms is restricted by contracts between the farmers and their marketing agent. In the past, these contracts have been calculated on a yearly base. Due to a switch in agricultural policy, these yearly contracts are currently more and more replaced by contracts calculated on a monthly base. These new contracts are assumed to restrict the flexibility of farmers to react on changes in milk price as well as on changes in fodder availability. Thus, the contract design is expected to influence farmers' ability to cope with risks and, thus, to influence the farm's gross margin variability. Applying a bioeconomic whole-farm model, the effects of price and weather risk as well as different risk-management strategies on the gross margin and the variability of the gross margin in Swiss dairy production are assessed under the 2 contract designs. We consider both risk-neutral and risk-averse behavior of farmers in our study. Results show that gross margin is slightly higher under the yearly than under the monthly contract. Variability of gross margin is also higher under the yearly than under the monthly contract. If the farmer is assumed to be risk averse, under both contracts he can reduce the coefficient of variation of the gross margin by almost 20% at opportunity costs below 1% of the gross margin. To reduce variability of gross margin under both contracts the size of the feedstock needs to be increased. This increase, however, must be considerably higher under the monthly contract than under the yearly contract. An additional risk-management strategy under a monthly contract is an increase in the area used as intensive pasture to ensure fodder availability in years with unfavorable weather. Under the yearly contract, an increase in the area used as extensive pasture is shown to be more favorable because it increases the amount of direct payments the farmer will receive. Additional restrictions in farm management due to a monthly

  6. The health risk of the agricultural production in potentially contaminated sites: an environmental-health risk analysis

    Directory of Open Access Journals (Sweden)

    Giovanni Russo

    2012-12-01

    Full Text Available Rural areas are often interested by pollution phenomena generated by agricultural activities with a high use of pesticides and/or by anthropic activities, such as industrial plants or illegal waste disposal sites, which may cause even long-range contamination. The risk for human health from the pollutants present in the environment can be quantitatively evaluated by the environmental health risk analysis set out in the Italian Legislative Decree no. 152/2006 (Italian Regulation, 2006. This analysis is the best technical-normative tool to estimate the health risks linked to the pollutants present in the environment but it does not consider the specificity of agricultural soils or the contamination of agricultural products. This study aims to provide this missing technical-normative data by identifying and applying a suitable methodology to evaluate the health risk caused by the ingestion of agricultural products grown in contaminated soils. The risk analysis was applied to two contaminated areas in southern Italy using an innovative methodology based on widely accepted parameters for the determination of polycyclic aromatic hydrocarbons (PAHs soil-plant bio-transfer factor in the case of horticultural crops. In addition, some concentration limits of PAHs in agricultural soils are proposed that may be of help to the competent authorities (health agencies, local authorities in delineating the areas requiring strict health surveillance of the food products cultivated.

  7. What risks do herbal products pose to the Australian community?

    Science.gov (United States)

    Byard, Roger W; Musgrave, Ian; Maker, Garth; Bunce, Michael

    2017-02-06

    Traditional herbal products are widely used in Australia to treat a broad range of conditions and diseases. It is popularly believed that these products are safer than prescribed drugs. While many may be safe, it is worrying that the specific effects and harmful interactions of a number of their components with prescription medications is not well understood. Some traditional herbal preparations contain heavy metals and toxic chemicals, as well as naturally occurring organic toxins. The effects of these substances can be dire, including acute hepatic and renal failure, exacerbation of pre-existing conditions and diseases, and even death. The content and quality of herbal preparations are not tightly controlled, with some ingredients either not listed or their concentrations recorded inaccurately on websites or labels. Herbal products may also include illegal ingredients, such as ephedra, Asarum europaeum (European wild ginger) and endangered animal species (eg, snow leopard). An additional problem is augmentation with prescription medications to enhance the apparent effectiveness of a preparation. Toxic substances may also be deliberately or inadvertently added: less expensive, more harmful plants may be substituted for more expensive ingredients, and processing may not be adequate. The lack of regulation and monitoring of traditional herbal preparations in Australia and other Western countries means that their contribution to illness and death is unknown. We need to raise awareness of these problems with health care practitioners and with the general public.

  8. Workable methods for risks control in the food chain production.

    Directory of Open Access Journals (Sweden)

    Lucilla Iacumin

    2008-04-01

    Full Text Available Several food pathologies due to new or already known micro-organisms occur all over the world every year. Food concerned are more and more frequently traditional typical, ethnical products coming from fast or slow food systems. Most of food-borne pathologies develop through neurological, gastrointestinal (watery, bloody or persistent diarrhoea abdominal pain, sickness and vomiting. The causes of these epidemics, apart from the concerned pathogen, are linked to the contaminated first matter or to contaminations occurred during food processing and consequently due to the lack of employment of the most fundamental sanitary measures and to non-control of the critical points of the HACCP (Hazard Analysis Critical Control Point systems. The pre-requirements to promote food health consist of the implementation of good agriculture husbandry and production practices, the use of HACCP systems, the training of the workers employed in the different productive rows and in the adoption of identification and traceability systems. The EU implemented the so-called hygiene pack, that is a list of rules imposing food control in each processing, marketing and consumption phase, from husbandry or cropping to consumer’s table, to promote health in food (circulating all over Europe.

  9. Employing high resolution satellite imagery to document a rapid glacier surge in the Karakoram - risks and opportunities for hazard assessment

    Science.gov (United States)

    Steiner, J. F.; Kraaijenbrink, P. D. A.; Jiduc, S. G.; Immerzeel, W. W.

    2017-12-01

    in combination with a scientific evaluation of the data can be employed to provide (a) immediate hazard assessments in remote mountainous regions and (b) to raise local awareness about these risks and provide pathways for local stakeholders to assess future hazard potentials.

  10. Environmental degradation, global food production, and risk for large-scale migrations

    International Nuclear Information System (INIS)

    Doeoes, B.R.

    1994-01-01

    This paper attempts to estimate to what extent global food production is affected by the ongoing environmental degradation through processes, such as soil erosion, salinization, chemical contamination, ultraviolet radiation, and biotic stress. Estimates have also been made of available opportunities to improve food production efficiency by, e.g., increased use of fertilizers, irrigation, and biotechnology, as well as improved management. Expected losses and gains of agricultural land in competition with urbanization, industrial development, and forests have been taken into account. Although estimated gains in food production deliberately have been overestimated and losses underestimated, calculations indicate that during the next 30-35 years the annual net gain in food production will be significantly lower than the rate of world population growth. An attempt has also been made to identify possible scenarios for large-scale migrations, caused mainly by rapid population growth in combination with insufficient local food production and poverty. 18 refs, 7 figs, 6 tabs

  11. Dairy product consumption and risk of hip fracture: a systematic review and meta-analysis

    OpenAIRE

    Bian, Shanshan; Hu, Jingmin; Zhang, Kai; Wang, Yunguo; Yu, Miaohui; Ma, Jie

    2018-01-01

    Background Dairy product consumption may affect the risk of hip fracture, but previous studies have reported inconsistent findings. The primary aim of our meta-analysis was to examine and quantify the potential association of dairy product consumption with risk of hip fracture. Methods We searched the databases of PubMed and EMBASE for relevant articles from their inception through April 17, 2017. The final analysis included 10 cohort studies and 8 case-control studies. Random-effects models ...

  12. RISK CONNECTED WITH AIRCRAFT PRODUCTION IN ACCORDANCE WITH MINIMUM EQUIPMENT LIST (MEL

    Directory of Open Access Journals (Sweden)

    R. V. Enikeev

    2014-01-01

    Full Text Available The article covers the problem of understanding of risk assessment necessity connected with aircraft production in accordance with Minimum Equipment List (MEL. The article presents calculation of fail-safe performance probability of Airbus A320 Family fuel system in the event of defect which rectification is postponed in accordance with MEL. The article also presents the results of risk assessment connected with aircraft production in accordance with MEL.

  13. Main health risks associated with Moroccan fishery products exported to European Union countries

    Directory of Open Access Journals (Sweden)

    S. Dahani

    2018-01-01

    Full Text Available The export of fishery products constitutes a very significant axis of the exchanges with certain countries, especially the countries of the European Union (EU. In Morocco, the exported fish products are controlled by the veterinarians of the National Office of the Health Security of Food products (NOHSF according to a procedure which is based on documentary control, identity and physical control and possibly analytical control. This control is complemented by monitoring plans. Currently, the product control has become a more demanding task due to the significant volume of fish production, the lack of means and human resources, hence the need for a novel approach to the control of fishery products based on risk analysis, which involves the establishment of appropriate controls aiming at guaranteeing that the products are safe. The objective of this work is the hierarchization of the main health risks associated to the fishery products exported to EU countries by Morocco. This approach is based on an overall analysis and statistical analysis using principal components analysis (PCA of the health profile of the notifications of the Rapid Alert System for the foodstuffs and feeding stuffs (RASFF from 1981 to 2015. This work allowed the development of a criticality matrix which specifies the health profile of species of products exported to EU countries via Morocco according to species, of danger and type of product. The control of fishery products based on risk analysis is a very important approach for the Moroccan competent authority.

  14. Decentralised bioenergy systems: A review of opportunities and threats

    International Nuclear Information System (INIS)

    Mangoyana, Robert B.; Smith, Timothy F.

    2011-01-01

    Decentralised bioenergy systems are receiving increasing attention due to the potential ability to support local development, create local employment, and contribute to climate change mitigation. These issues, along with other bioenergy sustainability issues, are reviewed through eighteen international case studies with the objective of identifying opportunities and threats to decentralised bioenergy systems. The case studies were selected based on feedstock type, bioenergy type, production capacity, synergistic alliances, ownership structure and physical locations. This variation was used to provide a basis for evaluating opportunities and threats from different contexts. Commercial viability remains the primary concern for the sustainability of decentralised bioenergy systems. There are, however, opportunities for compounding benefits through integrating small scale decentralised bioenergy systems with other production systems. Integrated production, including closed loop models, allow waste materials from one process to be used as inputs in other production processes, and thereby increasing economic, social and environmental outcomes. Synergistic opportunities along the bioenergy production chain, which include feedstock production, bioenergy marketing and distribution could also be exploited by communities and other investors to minimise decentralised production risk. - Research Highlights: → Small scale decentralised bioenergy production is a potentially sustainable energy system. →Economic viability limits small scale decentralised bioenergy production. → Synergistic alliances along the bioenergy production chain could enhance viability.

  15. Three essays on productivity and risk, marketing decisions, and changes in well-being over time

    OpenAIRE

    Larochelle, Catherine

    2011-01-01

    This dissertation is composed of three essays; the first two examine the decision-making of potato producing households in Bolivia and the third examines well-being changes among Zimbabwe households. The first essay entitled â The role of risk mitigation in production efficiency: A case study of potato cultivation in the Bolivian Andesâ estimates the costs of self-managing environmental risk through activity and environmental diversification. Risk management has the potential to reduce in...

  16. Product Diversification in the European Banking Industry: Risk and Loan Pricing Implications

    OpenAIRE

    Lepetit , Laetitia; Nys , Emmanuelle; Rous , Philippe; Tarazi , Amine

    2005-01-01

    The purpose of this paper is to investigate the relationship between bank risk and product diversification in the changing structure of the European banking industry. Based on a broad set of European banks for the period 1996-2002, our study shows that banks expanding into non-interest income activities present higher risk than banks which mainly supply loans. Whereas previous studies (mainly on U.S. banks) focused on portfolio diversification effects we explore risk implications of cross-sel...

  17. Projected impacts to the production of outdoor recreation opportunities across US state park systems due to the adoption of a domestic climate change mitigation policy

    International Nuclear Information System (INIS)

    Smith, Jordan W.; Leung, Yu-Fai; Seekamp, Erin; Walden-Schreiner, Chelsey; Miller, Anna B.

    2015-01-01

    Highlights: • A technical efficiency model identifies where state park systems can be improved. • The technical efficiency model is joined with output of CC policy simulations. • Shifts in operating expenditure under the CC mitigation policy are estimated. • Results reveal substantial variability across states. • Increasing technical efficiency is the best solution to adapt to CC policy impacts. - Abstract: Numerous empirical and simulation-based studies have documented or estimated variable impacts to the economic growth of nation states due to the adoption of domestic climate change mitigation policies. However, few studies have been able to empirically link projected changes in economic growth to the provision of public goods and services. In this research, we couple projected changes in economic growth to US states brought about by the adoption of a domestic climate change mitigation policy with a longitudinal panel dataset detailing the production of outdoor recreation opportunities on lands managed in the public interest. Joining empirical data and simulation-based estimates allow us to better understand how the adoption of a domestic climate change mitigation policy would affect the provision of public goods in the future. We first employ a technical efficiency model and metrics to provide decision makers with evidence of specific areas where operational efficiencies within the nation's state park systems can be improved. We then augment the empirical analysis with simulation-based changes in gross state product (GSP) to estimate changes to the states’ ability to provide outdoor recreation opportunities from 2014 to 2020; the results reveal substantial variability across states. Finally, we explore two potential solutions (increasing GSP or increasing technical efficiency) for addressing the negative impacts on the states’ park systems operating budgets brought about by the adoption of a domestic climate change mitigation policy; the

  18. Risk mitigation strategies for viral contamination of biotechnology products: consideration of best practices.

    Science.gov (United States)

    Rosenberg, Amy S; Cherney, Barry; Brorson, Kurt; Clouse, Kathleen; Kozlowski, Steven; Hughes, Patricia; Friedman, Rick

    2011-01-01

    CONFERENCE PROCEEDING Proceedings of the PDA/FDA Adventitious Viruses in Biologics: Detection and Mitigation Strategies Workshop in Bethesda, MD, USA; December 1-3, 2010 Guest Editors: Arifa Khan (Bethesda, MD), Patricia Hughes (Bethesda, MD) and Michael Wiebe (San Francisco, CA) Viral contamination of biotech product facilities is a potentially devastating manufacturing risk and, unfortunately, is more common than is generally reported or previously appreciated. Although viral contaminants of biotech products are thought to originate principally from biological raw materials, all potential process risks merit evaluation. Limitations to existing methods for virus detection are becoming evident as emerging viruses have contaminated facilities and disrupted supplies of critical products. New technologies, such as broad-based polymerase chain reaction screens for multiple virus types, are increasingly becoming available to detect adventitious viral contamination and thus, mitigate risks to biotech products and processes. Further, the industry embrace of quality risk management that promotes improvements in testing stratagems, enhanced viral inactivation methods for raw materials, implementation and standardization of robust viral clearance procedures, and efforts to learn from both epidemiologic screening of raw material sources and from the experience of other manufacturers with regard to this problem will serve to enhance the safety of biotech products available to patients. Based on this evolving landscape, we propose a set of principles for manufacturers of biotech products: Pillars of Risk Mitigation for Viral Contamination of Biotech Products.

  19. Risk and profitability of animal and crop production in Slovak farms

    Directory of Open Access Journals (Sweden)

    Marián Tóth

    2017-10-01

    Full Text Available The paper focuses on profitability and risk of crop and animal production based on an analysis of farms operating in Slovak Republic. The individual farm data used for the analysis are from the database of Ministry of Agriculture and Rural Development of the Slovak Republic. For our analysis, data were selected according to the farm production orientation to the subset of crop farms and animal farms. The selecting criterion for production orientation was the percentage share of revenues from crop production, or revenues from animal production from the overall revenues from own products and services. We analyse profitability of farms divided into groups based on the type of production into crop and animal farms (according to the share in sales from crop or animal production. Using descriptive statistics and portfolio theory we simulate the total farm profitability and volatility of animal and crop production in Slovakia. The modified Markowitz portfolio theory approach was used to estimate the total risk of portfolios of crop and animal farms. Based on the results we conclude that in the long run crop farms are profitable and profit from crop production is used to cover the losses from animal production in mixed farms. Farms focused on animal production only are efficient and profitable, but the profitability is lower in comparison with crop farms. Animal farms results are less volatile than crop farms. Large farms tend to production with lower value added and can generate enough profit for the owner.

  20. Epidemiology of Trichinella infection in the horse: the risk from animal product feeding practices.

    Science.gov (United States)

    Murrell, K D; Djordjevic, M; Cuperlovic, K; Sofronic, Lj; Savic, M; Djordjevic, M; Damjanovic, S

    2004-09-02

    A discovery in 2002 of a Trichinella spiralis-infected horse in Serbia offered an opportunity to conduct needed epidemiological studies on how horses, considered herbivores, acquire a meat-borne parasite. This enigma has persisted since the first human outbreaks from infected horse meat occurred in then 1970s. The trace back of the infected horse to a farm owner was carried out. Interviews and investigations on the farm led to the conclusion that the owner had fed the horse food waste in order to condition the horse prior to sale. Further investigations were then carried out to determine the frequency of such practices among horse owners. Based on interviews of horse producers at local horse markets, it was revealed that the feeding of animal products to horses was a common practice. Further, it was alleged that many horses, particularly those in poor nutritional condition would readily consume meat. A subsequent series of trials involving the experimental feeding of 219 horses demonstrated that 32% would consume meat patties. To confirm that horses would eat infected meat under normal farm conditions, three horses were offered infected ground pork balls containing 1100 larvae. All three became infected, and at necropsy at 32 weeks later, were still positive by indirect IFA testing, but not by ELISA using an excretory-secretory (ES) antigen. This result indicates that further study is needed on the nature of the antigen(s) used for potential serological monitoring and surveillance of horse trichinellosis, especially the importance of antigenic diversity. The experimentally-infected horses also had very low infection levels (larvae per gram of muscle) at 32 weeks of infection, and although the public health consequences are unknown, the question of whether current recommended inspection procedures based on pepsin digestion of selected muscle samples require sufficient quantities of muscle should be addressed. It is concluded that horses are more willing to consume

  1. Harnessing Genetic Diversity of Wild Gene Pools to Enhance Wheat Crop Production and Sustainability: Challenges and Opportunities

    Directory of Open Access Journals (Sweden)

    Carla Ceoloni

    2017-12-01

    Full Text Available Wild species are extremely rich resources of useful genes not available in the cultivated gene pool. For species providing staple food to mankind, such as the cultivated Triticum species, including hexaploid bread wheat (Triticum aestivum, 6x and tetraploid durum wheat (T. durum, 4x, widening the genetic base is a priority and primary target to cope with the many challenges that the crop has to face. These include recent climate changes, as well as actual and projected demographic growth, contrasting with reduction of arable land and water reserves. All of these environmental and societal modifications pose major constraints to the required production increase in the wheat crop. A sustainable approach to address this task implies resorting to non-conventional breeding strategies, such as “chromosome engineering”. This is based on cytogenetic methodologies, which ultimately allow for the incorporation into wheat chromosomes of targeted, and ideally small, chromosomal segments from the genome of wild relatives, containing the gene(s of interest. Chromosome engineering has been successfully applied to introduce into wheat genes/QTL for resistance to biotic and abiotic stresses, quality attributes, and even yield-related traits. In recent years, a substantial upsurge in effective alien gene exploitation for wheat improvement has come from modern technologies, including use of molecular markers, molecular cytogenetic techniques, and sequencing, which have greatly expanded our knowledge and ability to finely manipulate wheat and alien genomes. Examples will be provided of various types of stable introgressions, including pyramiding of different alien genes/QTL, into the background of bread and durum wheat genotypes, representing valuable materials for both species to respond to the needed novelty in current and future breeding programs. Challenging contexts, such as that inherent to the 4x nature of durum wheat when compared to 6x bread wheat, or

  2. Dairy products and colorectal cancer risk : a systematic review and meta-analysis of cohort studies

    NARCIS (Netherlands)

    Aune, D.; Lau, R.; Chan, D.S.M.; Vieira, R.; Greenwood, D.C.; Kampman, E.; Norat, T.

    2012-01-01

    Background: Previous studies of the association between intake of dairy products and colorectal cancer risk have indicated an inverse association with milk, however, the evidence for cheese or other dairy products is inconsistent. Methods: We conducted a systematic review and meta-analysis to

  3. The impacts of product design changes on supply chain risk: a case study

    OpenAIRE

    Lin, Yong; Zhou, Li

    2011-01-01

    Purpose: The main purpose of this paper is to address the impact of product design changes on supply chain risk, and to identify the supply chain risk dimensions in the Chinese special-purpose vehicle (SPV) industry in the context of product design change.\\ud \\ud Design/methodology/approach: Case study methodology is adopted to describe the current situation of supply chain risk management in the Chinese SPV industry. Data are mainly collected from in-depth semi-structured interviews, and a c...

  4. Risk analysis of sterile production plants: a new and simple, workable approach.

    Science.gov (United States)

    Gapp, Guenther; Holzknecht, Peter

    2011-01-01

    A sterile active ingredient plant and a sterile finished dosage filling plant both comprise very complex production processes and systems. The sterility of the final product cannot be assured solely by sterility testing, in-process controls, environmental monitoring of cleanrooms, and media fill validations. Based on more than 15 years experience, 4 years ago the authors created a new but very simple approach to the risk analysis of sterile plants. This approach is not a failure mode and effects analysis and therefore differs from the PDA Technical Report 44 Quality Risk Management for Aseptic Processes of 2008. The principle involves specific questions, which have been defined in the risk analysis questionnaire in advance, to be answered by an expert team. If the questionnaire item is dealt with appropriately, the answer is assigned a low-risk number (1) and if very weak or deficient it gets a high-risk number (5). In addition to the numbers, colors from green (not problematic) through orange to red (very problematic) are attributed to make the results more striking. Because the individual units of each production plant have a defined and different impact on the overall sterility of the final product, different risk emphasis factors have to be taken into account (impact factor 1, 3, or 5). In a well run cleanroom, the cleanroom operators have a lower impact than other units with regard to the contamination risk. The resulting number of the analyzed production plant and the diagram of the assessment subsequently offers very important and valuable information about a) the risk for microbiological contamination (sterility/endotoxins) of the product, and b) the compliance status of the production plant and the risk of failing lots, as well as probable observations of upcoming regulatory agency audits. Both items above are highly important for the safety of the patient. It is also an ideal tool to identify deficient or weak systems requiring improvement and upgrade

  5. Examining relationships between multiple health risk behaviors, well-being, and productivity.

    Science.gov (United States)

    Evers, Kerry E; Castle, Patricia H; Prochaska, James O; Prochaska, Janice M

    2014-06-01

    Traditionally, the concept of health promotion has emphasized the reduction of health risk behaviors to reduce disease and impairment. Well-being research expands this focus to include positive constructs such as thriving, productivity, life-evaluation, and emotional and physical health. The objective of the present study was to examine the relationships between health risk behaviors and specific measures of individual well-being. Participants (N = 790) from 49 states completed a one-time online assessment that included the Life-Evaluation Index, Emotional and Physical Health Ladders, the Health Risk Intervention Assessment, and the Work Productivity and Activity Improvement Questionnaire for General Health. Life Evaluation and physical and emotional health were all inversely related to the number of health risk behaviors, with higher well-being scores associated with lower number of risk behaviors. Across the three Life Evaluation categories (Suffering, Struggling, and Thriving) the number of health risk behaviors decreased, productivity loss decreased, and emotional and physical health increased. The results add to previous research on how reducing multiple health risk behaviors can be combined with well-being, i.e., an emphasis on increasing life-evaluation, emotional and physical health, better functioning, and productivity.

  6. Association of trypanosomosis risk with dairy cattle production in western Kenya

    Directory of Open Access Journals (Sweden)

    G.L. Mugunieri

    2005-09-01

    Full Text Available Dairy cattle reared in western Kenya are exposed to medium to high levels of trypanosomosis risk. The social background, farm characteristics and dairy cattle productivity of 90 and 30 randomly selected farmers from medium- and high-risk trypanosomosis areas, respectively, were compared. All the 120 farmers were visited between July and August 2002. Data analysis was performed using descriptive statistics and analysis of variance. The results showed that increased trypanosomosis risk represented by an increase in disease prevalence in cattle of 1% to 20 % decreased the density of dairy cattle by 53 % and increased the calving interval from 14 to 25 months. The increased risk was also associated with a significant increase in cattle mortalities and in a lactation period of 257 to 300 days. It was concluded that removal of the trypanosomosis constraint on dairy production would lead to expansion of dairying since the domestic demand for dairy products is expected to increase.

  7. Meteorological risks and impacts on crop production systems in Belgium

    Science.gov (United States)

    Gobin, Anne

    2013-04-01

    Extreme weather events such as droughts, heat stress, rain storms and floods can have devastating effects on cropping systems. The perspective of rising risk-exposure is exacerbated further by projected increases of extreme events with climate change. More limits to aid received for agricultural damage and an overall reduction of direct income support to farmers further impacts farmers' resilience. Based on insurance claims, potatoes and rapeseed are the most vulnerable crops, followed by cereals and sugar beets. Damages due to adverse meteorological events are strongly dependent on crop type, crop stage and soil type. Current knowledge gaps exist in the response of arable crops to the occurrence of extreme events. The degree of temporal overlap between extreme weather events and the sensitive periods of the farming calendar requires a modelling approach to capture the mixture of non-linear interactions between the crop and its environment. The regional crop model REGCROP (Gobin, 2010) enabled to examine the likely frequency and magnitude of drought, heat stress and waterlogging in relation to the cropping season and crop sensitive stages of six arable crops: winter wheat, winter barley, winter rapeseed, potato, sugar beet and maize. Since crop development is driven by thermal time, crops matured earlier during the warmer 1988-2008 period than during the 1947-1987 period. Drought and heat stress, in particular during the sensitive crop stages, occur at different times in the cropping season and significantly differ between two climatic periods, 1947-1987 and 1988-2008. Soil moisture deficit increases towards harvesting, such that earlier maturing winter crops may avoid drought stress that occurs in late spring and summer. This is reflected in a decrease both in magnitude and frequency of soil moisture deficit around the sensitive stages during the 1988-2008 period when atmospheric drought may be compensated for with soil moisture. The risk of drought spells during

  8. Do Antibiotics Reduce Production Risk for U.S. Pork Producers?

    OpenAIRE

    Liu, Xuanli; Miller, Gay Y.; McNamara, Paul E.

    2005-01-01

    Production risk from live weight variation of market pigs has become a more important concern in U.S. swine production. Packers are concerned about the variation in carcass size because of the demand for standardized cuts and the use of automation in the slaughter process. Swine producers care about standardized pigs because of revenue implications and possible links to animal health and productivity. Pig size variation can be due to various condition and inputs including antibiotics. However...

  9. A risk assessment approach to support the launching of new products, services or processes

    OpenAIRE

    Steen, Riana

    2015-01-01

    This is the accepted, refereed and final manuscript to the article published This research paper aims to develop a practical method to highlight certain key risk factors involved in the product development process. A new definition of the term “launch risk” is introduced in this work. The term is defined as the uncertainty about and severity of the consequences of failed launch. The launch could be the further development of existing products or the introduction of new products/services or...

  10. Television advertisement format and the provision of risk information about prescription drug products.

    Science.gov (United States)

    Glinert, Lewis H; Schommer, Jon C

    2005-06-01

    Considerable attention has been afforded to analyzing the content of and assessing consumers' reaction to print direct-to-consumer drug ads, but not so for televised ads. To determine whether advertisements with different risk severity and risk presentation would significantly affect viewers' (1) recall of information contained in the advertisement, (2) evaluation of the advertisement, and (3) perceptions of the advertised product's risks. Data were collected from a sample of 135 first-year pharmacy students at a Midwestern college of pharmacy. After viewing 1 of the 6 advertisements designed for this study, participants were asked to complete a self-administered survey. Chi-square and analysis of variance were used to analyze the data. A 2x3 between subjects design was used to test the effects of 2 levels of risk severity (high- vs low-risk severity) and 3 levels of risk presentation (original ad containing integrated risk message, deintegrated risk message/dual modality using male voice-over, deintegrated risk message/dual modality using female voice-over). Results of analysis of variance procedures revealed that deintegrating risk information by placing it at the end of the advertisement and the use of captions in addition to oral messages (dual modality) (1) improved the recall of general and specific side effect information, (2) led to a perception that the advertisement had greater informational content, (3) resulted in lower Advertisement Distraction, and (4) lessened cognitive and affective aspects of information overload for the advertisement containing the high-risk severity medication. However, this pattern of findings was not found for the low-risk severity medication. Alternative methods for presenting risk information in direct-to-consumer ads affected some aspects of information recall and advertisement evaluation, but were not shown to affect risk perceptions regarding the advertised products.

  11. The case of the high-risk safety product.

    Science.gov (United States)

    Chew, W B; Blodgett, T B; Wallin, W R; Meyers, G C; Holden, B; Johnson, E W; Smith, N C; Ducker, W

    1992-01-01

    After several days of meetings, J.F. Winchester, president of MDC Industries, felt no closer to a decision. MDC, a manufacturer of wall and ceiling panels, was considering whether to exercise an option to buy a new and safer wallboard technology. The product was being touted as revolutionary, but, Winchester wondered, could MDC afford to carry the flag? According to its inventor, Robert Goerner, Smoke-Safe would be a vast improvement over standard safety-rated wallboard. With almost the same flame-retardant properties, Smoke-Safe had the advantage of giving off almost no fumes or smoke in fire tests. And, Winchester knew, most fire-related deaths are from smoke, not flames. Indeed, the numbers were grimly persuasive: 82% of fire-related injuries involving standard panels were caused by smoke inhalation. What's more, Smoke-Safe would cost about the same to manufacture as MDC's current wallboard. But MDC had several other good options for spending the $5 million Goerner was asking; building plastics was only one of its profit centers. And the prospect of launching a campaign to change building codes in order to market Smoke-Safe, which could spark a fight with competitors, was daunting. Since its current wallboard gave MDC only 18% of the wallboard market, many industry insiders speculated whether MDC had the market clout to influence major cities to revise their codes. Six experts in marketing, law, and ethics advise MDC Industries on how it can balance ethical and business imperatives in making its decision.

  12. Global Production Planning Process considering the Supply Risk of Overseas Manufacturing Sites

    Directory of Open Access Journals (Sweden)

    Hosang Jung

    2015-01-01

    Full Text Available Although global manufacturers can produce most of their final products in local plants, they need to source components or parts from desirable overseas manufacturing partners at low cost in order to fulfill customer orders. In this global manufacturing environment, capacity information for planning is usually imprecise owing to the various risks of overseas plants (e.g., foreign governments’ policies and labor stability. It is therefore not easy for decision-makers to generate a global production plan showing the production amounts at local plants and overseas manufacturing facilities operated by manufacturing partners. In this paper, we present a new global production planning process considering the supply risk of overseas manufacturing sites. First, local experts estimate the supply capacity of an overseas plant using their judgment to determine when the risk could occur and how large the risk impact would be. Next, we run a global production planning model with the estimated supply capacities. The proposed process systematically adopts the qualitative judgments of local experts in the global production planning process and thus can provide companies with a realistic global production plan. We demonstrate the applicability of the proposed process with a real world case.

  13. Cancer surgery: risks and opportunities.

    LENUS (Irish Health Repository)

    Coffey, J C

    2012-02-03

    In the recent past, several papers have pointed to the possibility that tumour removal generates a permissive environment in which tumour growth is potentiated. This phenomenon has been coined "perioperative tumour growth" and whilst it represents a departure in terms of our attitude to the surgical process, this concept was first hinted at by Paget(1) himself. Despite this, the time interval immediately before and after cancer surgery (i.e. the perioperative period) remains an underutilised interval during which chemotherapeutic regimens are rarely implemented. Herein, we present a summarised review of the literature that supports the concept that tumour removal may potentiate the growth of residual neoplastic disease. We also outline current knowledge regarding underlying mechanisms and in this manner highlight potential therapeutic entry points. Finally, we emphasise the urgent need for trials of agents that could protect patients against the harmful host-tumour interactions that may occur during the perioperative period.

  14. Operationalizing Lawfare: Opportunity and Risk

    Science.gov (United States)

    2017-05-25

    the United States Information Agency. Michael Barger, “ Psychological Operations Supporting Counterinsurgency: 4th PSYOP Group in Vietnam” (MMAS thesis ... Psychological Operations Supporting Counterinsurgency: 4th PSYOP Group in Vietnam” (MMAS thesis , US Army Command and General Staff College, 2007...OMB control number. PLEASE DO NOT RETURN YOUR FORM TO THE ABOVE ADDRESS. 1. REPORT DATE (DD-MM-YYYY) 25-05-2017 2. REPORT TYPE Master’s Thesis

  15. Limiting the financial risks of electricity generation capital investments under carbon constraints: Applications and opportunities for public policies and private investments

    Science.gov (United States)

    Newcomer, Adam

    Increasing demand for electricity and an aging fleet of generators are the principal drivers behind an increasing need for a large amount of capital investments in the US electric power sector in the near term. The decisions (or lack thereof) by firms, regulators and policy makers in response to this challenge have long lasting consequences, incur large economic and environmental risks, and must be made despite large uncertainties about the future operating and business environment. Capital investment decisions are complex: rates of return are not guaranteed; significant uncertainties about future environmental legislation and regulations exist at both the state and national levels---particularly about carbon dioxide emissions; there is an increasing number of shareholder mandates requiring public utilities to reduce their exposure to potentially large losses from stricter environmental regulations; and there are significant concerns about electricity and fuel price levels, supplies, and security. Large scale, low carbon electricity generation facilities using coal, such as integrated gasification combined cycle (IGCC) facilities coupled with carbon capture and sequestration (CCS) technologies, have been technically proven but are unprofitable in the current regulatory and business environment where there is no explicit or implicit price on carbon dioxide emissions. The paper examines two separate scenarios that are actively discussed by policy and decision makers at corporate, state and national levels: a future US electricity system where coal plays a role; and one where the role of coal is limited or nonexistent. The thesis intends to provide guidance for firms and policy makers and outline applications and opportunities for public policies and for private investment decisions to limit financial risks of electricity generation capital investments under carbon constraints.

  16. Municipal opportunities

    International Nuclear Information System (INIS)

    Cousens, D.; Chuddy, B.; Gleeson, A.; Leckie, D.; Wahl, K.; McGarry, D.

    1997-01-01

    The panel discussing market opportunities for municipal electric companies was moderated by Markham Mayor Don Cousens. He expressed himself in favour of deregulation and was optimistic about the benefits it will bring to municipal electric utilities and their customers. Barry Chuddy, General Manager of Business Development for TransAlta Energy discussed the advantages of recent cogeneration and district energy for municipal utilities in Ontario and Quebec, and expressed his support for incentive-based regulation based on a level playing field, competitive generation, and a reasonable charge for stranded assets. Toronto City Councillor Dan Leckie described cogeneration and district energy as a tremendous opportunity to reduce the cost of doing business in the city core through local job creation and by keeping money in the local economy. Karl Wahl, General Manager of Hydro Mississauga expressed optimism that the government will move expeditiously toward competition, choice and lower-cost supply. David McGarry, President of Elecsar Engineering of Sarnia spoke about the significant job creating potential that deregulation will bring to the electrical industry. He cited several examples from Ontario and British Columbia

  17. Understanding safety and production risks in rail engineering planning and protection.

    Science.gov (United States)

    Wilson, John R; Ryan, Brendan; Schock, Alex; Ferreira, Pedro; Smith, Stuart; Pitsopoulos, Julia

    2009-07-01

    Much of the published human factors work on risk is to do with safety and within this is concerned with prediction and analysis of human error and with human reliability assessment. Less has been published on human factors contributions to understanding and managing project, business, engineering and other forms of risk and still less jointly assessing risk to do with broad issues of 'safety' and broad issues of 'production' or 'performance'. This paper contains a general commentary on human factors and assessment of risk of various kinds, in the context of the aims of ergonomics and concerns about being too risk averse. The paper then describes a specific project, in rail engineering, where the notion of a human factors case has been employed to analyse engineering functions and related human factors issues. A human factors issues register for potential system disturbances has been developed, prior to a human factors risk assessment, which jointly covers safety and production (engineering delivery) concerns. The paper concludes with a commentary on the potential relevance of a resilience engineering perspective to understanding rail engineering systems risk. Design, planning and management of complex systems will increasingly have to address the issue of making trade-offs between safety and production, and ergonomics should be central to this. The paper addresses the relevant issues and does so in an under-published domain - rail systems engineering work.

  18. Robust Production Planning in Fashion Apparel Industry under Demand Uncertainty via Conditional Value at Risk

    Directory of Open Access Journals (Sweden)

    Abderrahim Ait-Alla

    2014-01-01

    Full Text Available This paper presents a mathematical model for robust production planning. The model helps fashion apparel suppliers in making decisions concerning allocation of production orders to different production plants characterized by different lead times and production costs, and in proper time scheduling and sequencing of these production orders. The model aims at optimizing these decisions concerning objectives of minimal production costs and minimal tardiness. It considers several factors such as the stochastic nature of customer demand, differences in production and transport costs and transport times between production plants in different regions. Finally, the model is applied to a case study. The results of numerical computations are presented. The implications of the model results on different fashion related product types and delivery strategies, as well as the model’s limitations and potentials for expansion, are discussed. Results indicate that the production planning model using conditional value at risk (CVaR as the risk measure performs robustly and provides flexibility in decision analysis between different scenarios.

  19. Risk Mapping of Bogie S2HD-9C Production Process that Take Effect on Production Fulfillment at PT. Barata Indonesia (Persero

    Directory of Open Access Journals (Sweden)

    Faza Yoshio Susanto

    2017-01-01

    Full Text Available PT Barata Indonesia (Persero is one of leading metal works company in Indonesia. It has 3 main business line which are engineering procurement and construction (EPC, industrial tools manufacturing, and foundry. As the company’s strategic objective in delivering quality product and service to the customer, PT Barata Indonesia should maintain their production process properly. One of the featured product of PT Barata Indonesia is bogie. The production process of bogie shows a fluctuative delivery fulfillment. It can be proved by the contract amendment information. Risk management can be used as the method to manage risk inside the production process of bogie. Therefore, this research is aimed to identify risks that may occur from each activities of bogie S2HD-9C’s production process. The risk identification is done by using fault tree analysis method in order to determine the root cause of each activity performed. The risk evaluation is done by using FMEA method which can classify the effects of failure based on the severity and occurrence of failure. Then continue to the risk mapping and risk mitigation determination for bogie S2HD-9C’s production process. Loss that caused by the emergence of risk also determined using value at risk method. Moreover, risk profile dashboard will be provided as the tools in managing risk.

  20. Managing the risks of the backfill production line from material acquisition to installation

    International Nuclear Information System (INIS)

    Kiviranta, Leena; Kumpulainen, Sirpa; Keto, Paula; Autio, Jorma; Siivonen, Markku; Koho, Petri

    2012-01-01

    Document available in extended abstract form only. The tunnel backfill of Finnish KBS-3V type repository for spent nuclear fuel consists of foundation layer that is installed at site, pre-compacted backfill blocks that fill most of the tunnel and bentonite pellets to fill the gap between blocks and tunnel wall. In order to ensure the quality, availability, and timely delivery of backfill materials and components, and further to ensure the fulfillment of the requirements and specifications set for backfilling of deposition tunnels, the backfill production line was explored step-by-step, and risks related were defined and analyzed. The work described in this paper was initiated by Posiva Oy and is reported in Keto et al. (2012). The first part of the backfill production line is described in Figure 1 for Friedland clay that is designed to be used for the backfill blocks. It consists of excavation, processing and delivery of materials to backfill production facility. Second part of the production line consists of manufacturing of the backfill components, and the third part is the installation. A preliminary risk assessment was done in 2011 for the acquisition of Friedland clay and manufacturing and installation of foundation layer, blocks and pellets. The critical points of the production line were determined using a material flow description where risk is defined as a probability of something unwanted to happen times the severity of the consequences. Risk analysis was performed by going through the whole backfill production line step by step and analyzing all the incidents, which have occurred (or might occur) during the backfilling operations. A risk number from 1 to 25 was given to each step of the chain depending on how long delay the problem causes and how often it occurs. Low risk was the target for each step of the chain, medium risk was considered tolerable, for high risks management actions to decrease the risk number were considered and extremely high risks