WorldWideScience

Sample records for production generally requires

  1. 9 CFR 113.450 - General requirements for antibody products.

    Science.gov (United States)

    2010-01-01

    ... Rivanol or card tests. Reactors to these supplemental tests shall not be used for production. Nonreactors... Rivanol or card tests. Reactors to these supplemental tests shall not be used for production. Nonreactors... bacterial count. One milliliter of each rehydrated sample, undiluted or diluted as prescribed in the Outline...

  2. Generalized product

    OpenAIRE

    Greco, Salvatore; Mesiar, Radko; Rindone, Fabio

    2014-01-01

    Aggregation functions on [0,1] with annihilator 0 can be seen as a generalized product on [0,1]. We study the generalized product on the bipolar scale [–1,1], stressing the axiomatic point of view. Based on newly introduced bipolar properties, such as the bipolar increasingness, bipolar unit element, bipolar idempotent element, several kinds of generalized bipolar product are introduced and studied. A special stress is put on bipolar semicopulas, bipolar quasi-copulas and bipolar copulas.

  3. 9 CFR 113.100 - General requirements for inactivated bacterial products.

    Science.gov (United States)

    2010-01-01

    ... instances, the guinea pig safety test provided in § 113.38 shall be conducted in place of the mouse safety... Outline of Production, an inactivated bacterial product shall meet the applicable requirements in this... in poultry as defined in the specific Standard Requirement or Outline of Production for the product...

  4. Technical products for radiation shielding. Shield assembled from lead blocks for radiation protection. General technical requirements

    International Nuclear Information System (INIS)

    1981-01-01

    The object of this standard description is the general technological requirements of 50 and 100 mm thick radiation protection shields assembled from lead blocks. The standard contains the definitions, types, parameters and dimensions of shields, their technical and acceptance criteria with testing methods, tagging, packaging, transportation and storage requirements, producer's liability. Some illustrated assembling examples, preferred parameters and dosimetry methods for shield inspection are given. (R.P.)

  5. 78 FR 64237 - Information Collection: General and Oil and Gas Production Requirements in the Outer Continental...

    Science.gov (United States)

    2013-10-28

    ... OCS Lands Act, other applicable laws, and BOEM regulations; and does not unreasonably interfere with.... The form requests general information about the reservoir and the company, volumetric data, and fluid...

  6. Safety of power transformers, power supplies, reactors and similar products - Part 1: General requirements and tests

    CERN Document Server

    International Electrotechnical Commission. Geneva

    1998-01-01

    This International Standard deals with safety aspects of power transformers, power supplies, reactors and similar products such as electrical, thermal and mechanical safety. This standard covers the following types of dry-type transformers, power supplies, including switch mode power supplies, and reactors, the windings of which may be encapsulated or non-encapsulated. It has the status of a group safety publication in accordance with IEC Guide 104.

  7. 21 CFR 211.180 - General requirements.

    Science.gov (United States)

    2010-04-01

    ...: GENERAL CURRENT GOOD MANUFACTURING PRACTICE FOR FINISHED PHARMACEUTICALS Records and Reports § 211.180 General requirements. (a) Any production, control, or distribution record that is required to be... good manufacturing practices brought by the Food and Drug Administration. [43 FR 45077, Sept. 29, 1978...

  8. 21 CFR 211.160 - General requirements.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 4 2010-04-01 2010-04-01 false General requirements. 211.160 Section 211.160 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) DRUGS..., drug product container, or closure that is subject to deterioration. (2) Determination of conformance...

  9. General lighting requirements for photosynthesis

    Energy Technology Data Exchange (ETDEWEB)

    Geiger, D.R. [Univ. of Dayton, OH (United States)

    1994-12-31

    A review of the general lighting requirements for photosynthesis reveals that four aspects of light are important: irradiance, quality, timing and duration. These properties of light affect photosynthesis by providing the energy that drives carbon assimilation as well as by exerting control over physiology, structure and morphology of plants. Irradiance, expressed as energy flux, W m{sup -2}, or photon irradiance, {mu}mol m{sup -2} s{sup -1}, determines the rate at which energy is being delivered to the photosynthetic reaction centers. Spectral quality, the wavelength composition of light, is important because photons differ in their probability of being absorbed by the light harvesting complex and hence their ability to drive carbon assimilation. Also the various light receptors for light-mediated regulation of plant form and physiology have characteristic absorption spectra and hence photons differ in their effectiveness for eliciting responses. Duration is important because both carbon assimilation and regulation are affected by the total energy or integrated irradiance delivered during a given period. Many processes associated with photosynthesis are time-dependent, increasing or decreasing with duration. Timing is important because the effectiveness of light in the regulation of plant processes varies with the phase of the diumal cycle as determined by the plant`s time-measuring mechanisms.

  10. 40 CFR 68.12 - General requirements.

    Science.gov (United States)

    2010-07-01

    ...) CHEMICAL ACCIDENT PREVENTION PROVISIONS General § 68.12 General requirements. (a) General requirements. The... the five-year accident history for the process as provided in § 68.42 of this part and submit it in... §§ 68.150 to 68.185. The RMP shall include a registration that reflects all covered processes. (b...

  11. 7 CFR 1942.117 - General requirements.

    Science.gov (United States)

    2010-01-01

    ... § 1942.117 General requirements. (a) Reserve requirements. Loans under this subpart are subject to the... 7 Agriculture 13 2010-01-01 2009-01-01 true General requirements. 1942.117 Section 1942.117 Agriculture Regulations of the Department of Agriculture (Continued) RURAL HOUSING SERVICE, RURAL BUSINESS...

  12. 40 CFR 141.70 - General requirements.

    Science.gov (United States)

    2010-07-01

    ...) NATIONAL PRIMARY DRINKING WATER REGULATIONS Filtration and Disinfection § 141.70 General requirements. (a... regulations establish criteria under which filtration is required as a treatment technique for public water... filtration requirements in § 141.73 and the disinfection requirements in § 141.72(b). (c) Each public water...

  13. 30 CFR 250.1000 - General requirements.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false General requirements. 250.1000 Section 250.1000... OPERATIONS IN THE OUTER CONTINENTAL SHELF Pipelines and Pipeline Rights-of-Way § 250.1000 General....1001, must meet the requirements in §§ 250.1000 through 250.1008. (2) A pipeline right-of-way grant...

  14. 7 CFR 205.400 - General requirements for certification.

    Science.gov (United States)

    2010-01-01

    ...) ORGANIC FOODS PRODUCTION ACT PROVISIONS NATIONAL ORGANIC PROGRAM Certification § 205.400 General requirements for certification. A person seeking to receive or maintain organic certification under the... 7 Agriculture 3 2010-01-01 2010-01-01 false General requirements for certification. 205.400...

  15. General requirements applicable to the production, inspection, processing, packaging and storage of various types of waste resulting from the reprocessing of fuels irradiated in pressurized light water reactors

    International Nuclear Information System (INIS)

    1982-09-01

    The Fundamental Safety Rules applicable to certain types of nuclear installation are intended to clarify the conditions of which observance, for the type of installation concerned and for the subject that they deal with, is considered as equivalent to compliance with regulatory French technical practice. These Rules should facilitate safety analysises and the clear understanding between persons interested in matters related to nuclear safety. They in no way reduce the operator's liability and pose no obstacle to statutory provisions in force. For any installation to which a Fundamental Safety Rule applies according to the foregoing paragraph, the operator may be relieved from application of the Rule if he shows proof that the safety objectives set by the Rule are attained by other means that he proposes within the framework of statutory procedures. Furthermore, the Central Service for the Safety of Nuclear Installations reserves the right at all times to alter any Fundamental Safety Rule, as required, should it deem this necessary, while specifying the applicability conditions. This rule is intended to define the general provisions applicable to the production, inspection, processing, packaging and storage of the different types of wastes resulting from the reprocessing of fuels irradiated in a PWR

  16. 9 CFR 91.3 - General export requirements.

    Science.gov (United States)

    2010-01-01

    ... finds such tests are not necessary to prevent the exportation of diseased animals from the United States. (c) Testing. All samples for tests required by §§ 91.5 through 91.13 for exportation of animals under... 9 Animals and Animal Products 1 2010-01-01 2010-01-01 false General export requirements. 91.3...

  17. 40 CFR 141.700 - General requirements.

    Science.gov (United States)

    2010-07-01

    ... described in §§ 141.721 through 141.722. (7) Systems must address significant deficiencies identified in... 40 Protection of Environment 22 2010-07-01 2010-07-01 false General requirements. 141.700 Section 141.700 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) WATER PROGRAMS...

  18. 36 CFR 72.10 - General requirements.

    Science.gov (United States)

    2010-07-01

    ..., Iowa, Kansas, Missouri, Montana, Nebraska, North Dakota, South Dakota, Utah, and Wyoming. Pacific... PARK AND RECREATION RECOVERY ACT OF 1978 Local Recovery Action Programs § 72.10 General requirements... Recreation Act of 1978, Pub. L. 95-625, (16 U.S.C. 2506); sec. 2 of Reorganization Plan No. 3 of 1950 (64...

  19. 19 CFR 146.21 - General requirements.

    Science.gov (United States)

    2010-04-01

    ... TREASURY (CONTINUED) FOREIGN TRADE ZONES Inventory Control and Recordkeeping System § 146.21 General requirements. (a) Systems capability. The operator shall maintain either manual or automated inventory control... English language copy of its written inventory control and recordkeeping systems procedures manual in...

  20. 36 CFR 220.4 - General requirements.

    Science.gov (United States)

    2010-07-01

    ... natural and physical environment and the relationship of people with that environment (see 40 CFR 1508.14... for environmental assessments, findings of no significant impact and categorical exclusions (FSM 1950... ENVIRONMENTAL POLICY ACT (NEPA) COMPLIANCE § 220.4 General requirements. (a) Proposed actions subject to the...

  1. 30 CFR 57.4200 - General requirements.

    Science.gov (United States)

    2010-07-01

    ... Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR METAL AND NONMETAL MINE SAFETY AND HEALTH SAFETY AND HEALTH STANDARDS-UNDERGROUND METAL AND NONMETAL MINES Fire Prevention and Control Firefighting Equipment § 57.4200 General requirements. (a) For fighting fires that could endanger...

  2. 30 CFR 56.4200 - General requirements.

    Science.gov (United States)

    2010-07-01

    ... Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR METAL AND NONMETAL MINE SAFETY AND HEALTH SAFETY AND HEALTH STANDARDS-SURFACE METAL AND NONMETAL MINES Fire Prevention and Control Firefighting Equipment § 56.4200 General requirements. (a) For fighting fires that could endanger...

  3. 36 CFR 72.30 - General requirements.

    Science.gov (United States)

    2010-07-01

    ... PARK AND RECREATION RECOVERY ACT OF 1978 Grants for Recovery Action Program Development, Rehabilitation and Innovation § 72.30 General requirements. Applicants must have an approved Recovery Action Program on file with the appropriate NPS Regional Office prior to applying for Rehabilitation or Innovation...

  4. 21 CFR 820.180 - General requirements.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false General requirements. 820.180 Section 820.180 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL... minimize deterioration and to prevent loss. Those records stored in automated data processing systems shall...

  5. 47 CFR 52.9 - General requirements.

    Science.gov (United States)

    2010-10-01

    ... telecommunications carriers; (2) Not unduly favor or disfavor any particular telecommunications industry segment or... 47 Telecommunication 3 2010-10-01 2010-10-01 false General requirements. 52.9 Section 52.9 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) COMMON CARRIER SERVICES (CONTINUED) NUMBERING...

  6. 21 CFR 640.25 - General requirements.

    Science.gov (United States)

    2010-04-01

    ... quality control testing under paragraph (b) of this section may be performed by a clinical laboratory...) Quality control testing. Each month four units prepared from different donors shall be tested at the end... quality control testing indicate that the product does not meet the prescribed requirements, immediate...

  7. Some general requirements for irradiation experiments

    Energy Technology Data Exchange (ETDEWEB)

    Myers, H P; Skjoeldebrand, R

    1960-05-15

    This paper is limited to the interests of the EAES-symposium, namely the use of reactors for materials research and testing, for convenience we exclude consideration of chemical effects and problems of coolant technology. Its purpose is to try to define the general requirements for irradiation experiments and the reactors housing them; to see what facilities for irradiation experiments are available within the European Atomic Energy Society countries and finally, to point out possible limitations of these facilities.

  8. REQUIREMENTS FOR A GENERAL INTERPRETATION THEORY

    Directory of Open Access Journals (Sweden)

    Anda Laura Lungu Petruescu

    2013-06-01

    Full Text Available Time has proved that Economic Analysis is not enough as to ensure all the needs of the economic field. The present study wishes to propose a new approach method of the economic phenomena and processes based on the researches made outside the economic space- a new general interpretation theory- which is centered on the human being as the basic actor of economy. A general interpretation theory must assure the interpretation of the causalities among the economic phenomena and processes- causal interpretation; the interpretation of the correlations and dependencies among indicators- normative interpretation; the interpretation of social and communicational processes in economic organizations- social and communicational interpretation; the interpretation of the community status of companies- transsocial interpretation; the interpretation of the purposes of human activities and their coherency – teleological interpretation; the interpretation of equilibrium/ disequilibrium from inside the economic systems- optimality interpretation. In order to respond to such demands, rigor, pragmatism, praxiology and contextual connectors are required. In order to progress, the economic science must improve its language, both its syntax and its semantics. The clarity of exposure requires a language clarity and the scientific theory progress asks for the need of hypotheses in the building of the theories. The switch from the common language to the symbolic one means the switch from ambiguity to rigor and rationality, that is order in thinking. But order implies structure, which implies formalization. Our paper should be a plea for these requirements, requirements which should be fulfilled by a modern interpretation theory.

  9. Device description and general physics requirements

    International Nuclear Information System (INIS)

    Neilson, G.H. Jr.

    1992-01-01

    To accomplish the dual goals set forth in the mission statement - determination of burning plasma physics and demonstration of fusion power production - requires a tokamak with special characteristics. A conceptual design for such a facility has been developed by the CIT/BPX Project team over a period of about 5 years. The process has drawn extensively upon the world tokamak physics data base as well as engineering experience gained on actual machines like Tokamak Fusion Test Reactor (TFTR) and the Alcators and on design studies for machines like the Long-Pulse Ignited Test experiment (LITE) and the Tokamak Fusion Core Experiment (TFCX). The Joint European Torus (JET) and Doublet III-D (DIII-D) experiments in particular have had a significant influence on the physics base. The resulting design incorporates features that have proven successful in tokamak experiments, combined with new features that are needed in the regime of high-power-density deuterium-tritium (D-T) fusion plasmas

  10. A GENERALIZATION OF TRADITIONAL KANO MODEL FOR CUSTOMER REQUIREMENTS ANALYSIS

    Directory of Open Access Journals (Sweden)

    Renáta Turisová

    2015-07-01

    Full Text Available Purpose: The theory of attractiveness determines the relationship between the technically achieved and customer perceived quality of product attributes. The most frequently used approach in the theory of attractiveness is the implementation of Kano‘s model. There exist a lot of generalizations of that model which take into consideration various aspects and approaches focused on understanding the customer preferences and identification of his priorities for a selling  product. The aim of this article is to outline another possible generalization of Kano‘s model.Methodology/Approach: The traditional Kano’s model captures the nonlinear relationship between reached attributes of quality and customer requirements. The individual attributes of quality are divided into three main categories: must-be, one-dimensional, attractive quality and into two side categories: indifferent and reverse quality. The well selling product has to contain the must-be attribute. It should contain as many one-dimensional attributes as possible. If there are also supplementary attractive attributes, it means that attractiveness of the entire product, from the viewpoint of the customer, nonlinearly sharply rises what has a direct positive impact on a decision of potential customer when purchasing the product. In this article, we show that inclusion of individual quality attributes of a product to the mentioned categories depends, among other things, also on costs on life cycle of the product, respectively on a price of the product on the market.Findings: In practice, we are often encountering the inclusion of products into different price categories: lower, middle and upper class. For a certain type of products the category is either directly declared by a producer (especially in automotive industry, or is determined by a customer by means of assessment of available market prices. To each of those groups of a products different customer expectations can be assigned

  11. 27 CFR 7.28 - General requirements.

    Science.gov (United States)

    2010-04-01

    ... statements of alcoholic content, all mandatory information required on labels by this part shall be in script.... Except for statements of alcoholic content, all mandatory information required on labels by this part... OF THE TREASURY LIQUORS LABELING AND ADVERTISING OF MALT BEVERAGES Labeling Requirements for Malt...

  12. 40 CFR 141.80 - General requirements.

    Science.gov (United States)

    2010-07-01

    ... service line replacement, and public education. These requirements are triggered, in some cases, by lead... requirements. (1) All water systems shall install and operate optimal corrosion control treatment as defined in... specified by the State under § 141.83. (f) Lead service line replacement requirements. Any system exceeding...

  13. 23 CFR 645.209 - General requirements.

    Science.gov (United States)

    2010-04-01

    ... FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION ENGINEERING AND TRAFFIC OPERATIONS UTILITIES... environmental and economic effects of any loss of productive agricultural land or any productivity of any agricultural land which would result from the disapproval of the use of such right-of-way for accommodation of...

  14. 27 CFR 4.38 - General requirements.

    Science.gov (United States)

    2010-04-01

    ... mandatory information required on labels by this part, except the alcoholic content statement, shall be in... OF THE TREASURY LIQUORS LABELING AND ADVERTISING OF WINE Labeling Requirements for Wine § 4.38... descriptive or explanatory information, the script, type, or printing of the mandatory information shall be of...

  15. 46 CFR Sec. 2 - General Agent's requirements.

    Science.gov (United States)

    2010-10-01

    ... chest items required for the intended voyage. Purchase for the account of the NSA, from recognized bona... respective domestic ports, only such items and quantities reflecting past experience of actual requirements. (b) Arrange for delivery on board to the custody of the Master all slop chest items purchased...

  16. 40 CFR 141.500 - General requirements.

    Science.gov (United States)

    2010-07-01

    ... before or at the first customer for filtered systems, or Cryptosporidium control under the watershed control plan for unfiltered systems; and (b) Compliance with the profiling and benchmark requirements in...

  17. 40 CFR 141.170 - General requirements.

    Science.gov (United States)

    2010-07-01

    ... recontamination by surface water runoff and a point downstream before or at the first customer for filtered...) Compliance with the profiling and benchmark requirements under the provisions of § 141.172. (b) A public...

  18. 7 CFR 322.5 - General requirements.

    Science.gov (United States)

    2010-01-01

    ... honeybees. (1) You may import live adult bees or live brood and essential nest substrate under this subpart..., DEPARTMENT OF AGRICULTURE BEES, BEEKEEPING BYPRODUCTS, AND BEEKEEPING EQUIPMENT Importation of Adult Honeybees, Honeybee Germ Plasm, and Bees Other Than Honeybees From Approved Regions § 322.5 General...

  19. 29 CFR 780.604 - General requirements.

    Science.gov (United States)

    2010-07-01

    ... follows: (a) Employment of the employee “primarily” in agriculture in the particular workweek. (b) This primary employment by a farmer. (c) Engagement by the farmer in raising livestock. (d) Engagement by the... employee. These requirements will be separately discussed in the following sections of this subpart. ...

  20. 29 CFR 1926.403 - General requirements.

    Science.gov (United States)

    2010-07-01

    ... ready and safe operation and maintenance of such equipment. (i) Working clearances. Except as required... sufficient durability to withstand the environment involved. (h) Identification of disconnecting means and... sufficient durability to withstand the environment involved. (i) 600 Volts, nominal, or less. This paragraph...

  1. 14 CFR 1204.403 - General requirements.

    Science.gov (United States)

    2010-01-01

    ... transaction has already been set-aside for small business by the contracting officer. (b) The appropriate... conferences and training sessions to inform small businesses of contracting opportunities with the Agency. (e) In accordance with Public Law 95-507, NASA will require contractors having contracts in excess of $1...

  2. 10 CFR 63.131 - General requirements.

    Science.gov (United States)

    2010-01-01

    ... are within the limits assumed in the licensing review; and (2) Natural and engineered systems and components required for repository operation, and that are designed or assumed to operate as barriers after... information on those parameters and natural processes pertaining to the geologic setting that may be changed...

  3. 10 CFR 60.140 - General requirements.

    Science.gov (United States)

    2010-01-01

    ... assumed in the licensing review; and (2) Natural and engineered systems and components required for repository operation, or which are designed or assumed to operate as barriers after permanent closure, are... of the natural and engineered elements of the geologic repository to meet the performance objectives...

  4. 49 CFR 178.801 - General requirements.

    Science.gov (United States)

    2010-10-01

    ... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION HAZARDOUS MATERIALS REGULATIONS SPECIFICATIONS FOR PACKAGINGS... transportation and are considered minimum requirements. Each packaging must be manufactured and assembled so as... design type refers to an IBC that does not differ in structural design, size, material of construction...

  5. 32 CFR 807.1 - General requirements.

    Science.gov (United States)

    2010-07-01

    ... Libraries for public use according to AFR 4-61. They will also advise requesters that these libraries are... disclosure policy office and to HQ USAF/CVAII, Washington DC 20330-5000. Also send information copies of such requests to the base public affairs office. Commands will supplement this requirement to include policies...

  6. 46 CFR 111.95-3 - General requirements.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false General requirements. 111.95-3 Section 111.95-3 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING ELECTRIC SYSTEMS-GENERAL REQUIREMENTS Electric Power-Operated Boat Winches § 111.95-3 General requirements. (a) Each electrical...

  7. Some remarks on a generalized vector product

    OpenAIRE

    ACOSTA-HUMÁNEZ, PRIMITIVO; ARANDA, MOISÉS; NÚÑEZ, REINALDO

    2011-01-01

    Abstract. In this paper we use a generalized vector product to construct an exterior form ⊥ : , where Finally, for n = k - 1 we introduce the reversing operation to study this generalized vector product over palindromic and antipalindromic vectors. Resumen. En este art&íacute;culo usamos un producto vectorial generalizado para construir una forma exterior ⊥ : , en donde como es natural, Finalmente, para n = k - 1 introducimos la operación reversar para estudiar este producto vectorial gene...

  8. 34 CFR 674.41 - Due diligence-general requirements.

    Science.gov (United States)

    2010-07-01

    ... 34 Education 3 2010-07-01 2010-07-01 false Due diligence-general requirements. 674.41 Section 674... POSTSECONDARY EDUCATION, DEPARTMENT OF EDUCATION FEDERAL PERKINS LOAN PROGRAM Due Diligence § 674.41 Due diligence—general requirements. (a) General. Each institution shall exercise due diligence in collecting...

  9. 47 CFR 61.41 - Price cap requirements generally.

    Science.gov (United States)

    2010-10-01

    ... 47 Telecommunication 3 2010-10-01 2010-10-01 false Price cap requirements generally. 61.41 Section... (CONTINUED) TARIFFS General Rules for Dominant Carriers § 61.41 Price cap requirements generally. (a... companies shall not bar a carrier from electing price cap regulation provided the carrier is otherwise...

  10. 30 CFR 817.81 - Coal mine waste: General requirements.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 3 2010-07-01 2010-07-01 false Coal mine waste: General requirements. 817.81... ACTIVITIES § 817.81 Coal mine waste: General requirements. (a) General. All coal mine waste disposed of in an... within a permit area, which are approved by the regulatory authority for this purpose. Coal mine waste...

  11. 30 CFR 816.81 - Coal mine waste: General requirements.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 3 2010-07-01 2010-07-01 false Coal mine waste: General requirements. 816.81... ACTIVITIES § 816.81 Coal mine waste: General requirements. (a) General. All coal mine waste disposed of in an... within a permit area, which are approved by the regulatory authority for this purpose. Coal mine waste...

  12. 49 CFR 659.21 - System security plan: general requirements.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 7 2010-10-01 2010-10-01 false System security plan: general requirements. 659.21... State Oversight Agency § 659.21 System security plan: general requirements. (a) The oversight agency shall require the rail transit agency to implement a system security plan that, at a minimum, complies...

  13. 9 CFR 113.300 - General requirements for live virus vaccines.

    Science.gov (United States)

    2010-01-01

    ... vaccines. 113.300 Section 113.300 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE... REQUIREMENTS Live Virus Vaccines § 113.300 General requirements for live virus vaccines. When prescribed in an applicable Standard Requirement or in the filed Outline of Production, a live virus vaccine shall meet the...

  14. Measuring and improving productivity in general radiology.

    Science.gov (United States)

    Wilt, Michelle A; Miranda, Rafael; Johnson, C Daniel; Love, Peggy Sue

    2010-10-01

    The aim of this study was to determine a method of measuring productivity among general radiographers in a moderate-sized hospital and to improve and sustain productivity within that work area. The average times needed to perform the 13 most common examinations were measured. Performance of the various examinations was tracked and multiplied by the time allocated per procedure; this measure was divided by the length of the work shift to determine productivity. Productivity measures were shared among the work group, and decisions to improve productivity (eg, whether to fill open positions) were made by group members. Average time spent per examination type was calculated (range, 10 minutes to 1 hour 16 minutes). At baseline (February 2008), group productivity was 50%. Productivity increased during the first year of monitoring and was sustained through November 2009 (productivity range, 57%-63%). Yearly savings from not filling open positions were estimated to be $174,000. Productivity in a general radiology work area can be measured. Consensus among the work group helped increase productivity and assess progress. This methodology, if widely adopted, could be standardized and used to compare productivity across departments and institutions. Copyright © 2010 American College of Radiology. Published by Elsevier Inc. All rights reserved.

  15. 47 CFR 18.109 - General technical requirements.

    Science.gov (United States)

    2010-10-01

    ... MEDICAL EQUIPMENT General Information § 18.109 General technical requirements. ISM equipment shall be... filtering to provide adequate suppression of emissions on frequencies outside the frequency bands specified...

  16. 7 CFR 322.28 - General requirements; restricted articles.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 5 2010-01-01 2010-01-01 false General requirements; restricted articles. 322.28... EQUIPMENT Importation and Transit of Restricted Articles § 322.28 General requirements; restricted articles. (a) The following articles from any region are restricted articles: (1) Dead bees of any genus; (2...

  17. 49 CFR 173.60 - General packaging requirements for explosives.

    Science.gov (United States)

    2010-10-01

    ... explosives contained in the package, so that neither interaction between the explosives and the packaging... 49 Transportation 2 2010-10-01 2010-10-01 false General packaging requirements for explosives. 173...-GENERAL REQUIREMENTS FOR SHIPMENTS AND PACKAGINGS Definitions, Classification and Packaging for Class 1...

  18. 31 CFR 50.10 - General disclosure requirements.

    Science.gov (United States)

    2010-07-01

    ... 31 Money and Finance: Treasury 1 2010-07-01 2010-07-01 false General disclosure requirements. 50.10 Section 50.10 Money and Finance: Treasury Office of the Secretary of the Treasury TERRORISM RISK INSURANCE PROGRAM Disclosures as Conditions for Federal Payment § 50.10 General disclosure requirements. (a...

  19. 46 CFR 111.20-1 - General requirements.

    Science.gov (United States)

    2010-10-01

    ... COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING ELECTRIC SYSTEMS-GENERAL REQUIREMENTS Transformer Construction, Installation, and Protection § 111.20-1 General requirements. Each transformer winding must be resistant to moisture, sea atmosphere, and oil vapor, unless special precautions...

  20. Directives and general design requirements for a small PWR

    International Nuclear Information System (INIS)

    Arrieta, L.A.

    1992-08-01

    A proposal of directives and general requirements for the development of a small PWR conceptual design is presented. These directives address the main safety, performance and economic design aspects. The purpose is to use this work as a base for a wide discussion, involving all project participants, culminating with the definition of the final directives and general requirements. (author)

  1. 30 CFR 784.11 - Operation plan: General requirements.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 3 2010-07-01 2010-07-01 false Operation plan: General requirements. 784.11... PLAN § 784.11 Operation plan: General requirements. Each application shall contain a description of the... INTERIOR SURFACE COAL MINING AND RECLAMATION OPERATIONS PERMITS AND COAL EXPLORATION SYSTEMS UNDER...

  2. 30 CFR 780.11 - Operation plan: General requirements.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 3 2010-07-01 2010-07-01 false Operation plan: General requirements. 780.11... PLAN § 780.11 Operation plan: General requirements. Each application shall contain a description of the... INTERIOR SURFACE COAL MINING AND RECLAMATION OPERATIONS PERMITS AND COAL EXPLORATION SYSTEMS UNDER...

  3. 48 CFR 801.602-70 - General review requirements.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false General review... AFFAIRS GENERAL DEPARTMENT OF VETERANS AFFAIRS ACQUISITION REGULATION SYSTEM Career Development, Contracting Authority, and Responsibilities 801.602-70 General review requirements. (a) Contracting officers...

  4. Industrial requirements for interactive product configurators

    DEFF Research Database (Denmark)

    Queva, Matthieu Stéphane Benoit; Probst, Christian W.; Vikkelsøe, Per

    2009-01-01

    The demand for highly customized products at low cost is driving the industry towards Mass Customization. Interactive product configurators play an essential role in this new trend, and must be able to support more and more complex features. The purpose of this paper is, firstly, to identify...... requirements for modern interactive configurators. Existing modeling and solving technologies for configuration are then reviewed and their limitations discussed. Finally, a proposition for a future product configuration system is described....

  5. 48 CFR 9903.202-1 - General requirements.

    Science.gov (United States)

    2010-10-01

    ... ACCOUNTING STANDARDS CONTRACT COVERAGE CAS Program Requirements 9903.202-1 General requirements. (a) A... subcontract is of the type or value exempted by 9903.201-1 or (ii) In the most recently completed cost... of Germany. (3) United Kingdom. (f) Educational institutions—disclosure requirements. (1) Educational...

  6. RPC Production at General Tecnica: a mass scale production

    International Nuclear Information System (INIS)

    Della Volpe, D.; Morganti, S.

    2006-01-01

    The construction of LHC has deeply changed the RPC production. The enormous amount of detector needed and the strong requirements on gas volume quality had a deep impact on the production chain and on the QC and QA at the production site. This basically has brought the RPC from an almost hand-crafted detector to a medium scale mass product. The most critical aspects of the production chain have been modified and/or improved introducing new and more rigorous QC and QA procedures to guarantee the detector quality and improve the management of storage and the procurement on materials. Here it will be presented the work carried on in the last four year at the production site to improve and check the quality and the results achieved. Something like 10000 RPC were produced between 2002 and 2005. Also a preliminary and rough analysis on the efficiencies of the various phases in the chain production based on ATLAS production will be presented

  7. General requirements applicable to the production, inspection, processing, packaging and storage of high activity wastes packed in glass form and resulting from the reprocessing of fuels irradiated in pressurized light water reactors

    International Nuclear Information System (INIS)

    1982-11-01

    The Fundamental Safety Rules applicable to certain types of nuclear installation are intended to clarify the conditions of which observance, for the type of installation concerned and for the subject that they deal with, is considered as equivalent to compliance with regulatory French technical practice. These Rules should facilitate safety analysises and the clear understanding between persons interested in matters related to nuclear safety. They in no way reduce the operator's liability and pose no obstacle to statutory provisions in force. For any installation to which a Fundamental Safety Rule applies according to the foregoing paragraph, the operator may be relieved from application of the Rule if he shows proof that the safety objectives set by the Rule are attained by other means that he proposes within the framework of statutory procedures. Furthermore, the Central Service for the Safety of Nuclear Installations reserves the right at all times to alter any Fundamental Safety Rule, as required, should it deem this necessary, while specifying the applicability conditions. This rule is intended to define the general provisions applicable to the production, inspection, processing, packaging and storage of wastes, resulting from the reprocessing of fuels irradiated in a PWR, packaged in the form of glass

  8. Generalized production planning problem under interval uncertainty

    Directory of Open Access Journals (Sweden)

    Samir A. Abass

    2010-06-01

    Full Text Available Data in many real life engineering and economical problems suffer from inexactness. Herein we assume that we are given some intervals in which the data can simultaneously and independently perturb. We consider the generalized production planning problem with interval data. The interval data are in both of the objective function and constraints. The existing results concerning the qualitative and quantitative analysis of basic notions in parametric production planning problem. These notions are the set of feasible parameters, the solvability set and the stability set of the first kind.

  9. 47 CFR 15.407 - General technical requirements.

    Science.gov (United States)

    2010-10-01

    ... National Information Infrastructure Devices § 15.407 General technical requirements. (a) Power limits: (1... information or the use of repetitive codes used by certain digital technologies to complete frame or burst...

  10. 16 CFR 1611.3 - Flammability-general requirement.

    Science.gov (United States)

    2010-01-01

    ... STANDARD FOR THE FLAMMABILITY OF VINYL PLASTIC FILM The Standard § 1611.3 Flammability—general requirement. The rate of burning shall not exceed 1.2 in./sec as judged by the average of five determinations...

  11. 9 CFR 113.64 - General requirements for live bacterial vaccines.

    Science.gov (United States)

    2010-01-01

    ... bacterial vaccines. 113.64 Section 113.64 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION... STANDARD REQUIREMENTS Live Bacterial Vaccines § 113.64 General requirements for live bacterial vaccines... bacterial vaccine shall meet the requirements in this section. (a) Purity test. Final container samples of...

  12. 40 CFR 451.3 - General reporting requirements.

    Science.gov (United States)

    2010-07-01

    ... AND STANDARDS CONCENTRATED AQUATIC ANIMAL PRODUCTION POINT SOURCE CATEGORY § 451.3 General reporting... authority of the use in a concentrated aquatic animal production facility subject to this part of any..., the permittee must provide an oral report to the permitting authority as soon as possible, preferably...

  13. 1 CFR 21.21 - General requirements: References.

    Science.gov (United States)

    2010-01-01

    ... 1 General Provisions 1 2010-01-01 2010-01-01 false General requirements: References. 21.21 Section... to test methods or consensus standards produced by a Federal agency that have replaced or preempted private or voluntary test methods or consensus standards in a subject matter area. (5) The reference is to...

  14. 22 CFR 62.8 - General program requirements.

    Science.gov (United States)

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false General program requirements. 62.8 Section 62.8 Foreign Relations DEPARTMENT OF STATE PUBLIC DIPLOMACY AND EXCHANGES EXCHANGE VISITOR PROGRAM General... purpose of sharing the language, culture, or history of their home country with Americans, provided such...

  15. 77 FR 6676 - Office of Inspector General; Contractor Requirements

    Science.gov (United States)

    2012-02-09

    ... POSTAL SERVICE 39 CFR Part 230 Office of Inspector General; Contractor Requirements AGENCY: Postal... for contractors employed by the Office of Inspector General. The rule also emphasizes consistency in contractor selection, and clarifies the OIG's exclusive authority to set qualifications and standards for its...

  16. 31 CFR 128.1 - General reporting requirements.

    Science.gov (United States)

    2010-07-01

    ...) Data pertaining to direct investment transactions are not required to be reported under this Part. (3... INTERNATIONAL CAPITAL AND FOREIGN-CURRENCY TRANSACTIONS AND POSITIONS General Information § 128.1 General... International Investment and Trade in Services Survey Act, as amended (22 U.S.C. 3101 et seq.); and E.O. 11961...

  17. 40 CFR 205.55-1 - General requirements.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 24 2010-07-01 2010-07-01 false General requirements. 205.55-1 Section 205.55-1 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) NOISE ABATEMENT PROGRAMS TRANSPORTATION EQUIPMENT NOISE EMISSION CONTROLS Medium and Heavy Trucks § 205.55-1 General...

  18. 30 CFR 71.201 - Sampling; general requirements.

    Science.gov (United States)

    2010-07-01

    ... MINES Sampling Procedures § 71.201 Sampling; general requirements. (a) Each operator shall take... required by this part with a sampling device approved by the Secretary and the Secretary of Health and Human Services under part 74 (Coal Mine Dust Personal Sampler Units) of this title. (b) Sampling devices...

  19. 30 CFR 70.201 - Sampling; general requirements.

    Science.gov (United States)

    2010-07-01

    ...; general requirements. (a) Each operator shall take respirable dust samples of the concentration of respirable dust in the active workings of the mine as required by this part with a sampling device approved... Personal Sampler Units) of this title. (b) Sampling devices shall be worn or carried directly to and from...

  20. General-purpose heat source development. Phase I: design requirements

    International Nuclear Information System (INIS)

    Snow, E.C.; Zocher, R.W.

    1978-09-01

    Studies have been performed to determine the necessary design requirements for a 238 PuO 2 General-Purpose Heat Source (GPHS). Systems and missions applications, as well as accident conditions, were considered. The results of these studies, along with the recommended GPHS design requirements, are given in this report

  1. 14 CFR 125.91 - Airplane requirements: General.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 3 2010-01-01 2010-01-01 false Airplane requirements: General. 125.91... AND OPERATIONS: AIRPLANES HAVING A SEATING CAPACITY OF 20 OR MORE PASSENGERS OR A MAXIMUM PAYLOAD CAPACITY OF 6,000 POUNDS OR MORE; AND RULES GOVERNING PERSONS ON BOARD SUCH AIRCRAFT Airplane Requirements...

  2. Crop succession requirements in agricultural production planning

    NARCIS (Netherlands)

    Klein Haneveld, W.K.; Stegeman, A.

    2005-01-01

    A method is proposed to write crop succession requirements as linear constraints in an LP-based model for agricultural production planning. Crop succession information is given in the form of a set of inadmissible successions of crops. The decision variables represent the areas where a certain

  3. 21 CFR 700.25 - Tamper-resistant packaging requirements for cosmetic products.

    Science.gov (United States)

    2010-04-01

    ... cosmetic products. 700.25 Section 700.25 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) COSMETICS GENERAL Requirements for Specific Cosmetic Products § 700.25 Tamper-resistant packaging requirements for cosmetic products. (a) General. Because most cosmetic liquid...

  4. 42 CFR 423.401 - General requirements for PDP sponsors.

    Science.gov (United States)

    2010-10-01

    ... sponsor is organized and licensed under State law as a risk bearing entity eligible to offer health insurance or health benefits coverage in each State in which it offers a prescription drug plan. If not... with State Law and Preemption by Federal Law § 423.401 General requirements for PDP sponsors. (a...

  5. 40 CFR 141.400 - General requirements and applicability.

    Science.gov (United States)

    2010-07-01

    ... system with fecally contaminated source water or with significant deficiencies subject to the treatment... 40 Protection of Environment 22 2010-07-01 2010-07-01 false General requirements and applicability. 141.400 Section 141.400 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) WATER...

  6. 31 CFR 50.30 - General participation requirements.

    Science.gov (United States)

    2010-07-01

    .... 50.30 Section 50.30 Money and Finance: Treasury Office of the Secretary of the Treasury TERRORISM RISK INSURANCE PROGRAM State Residual Market Insurance Entities; Workers' Compensation Funds § 50.30 General participation requirements. (a) Insurers. As defined in § 50.5(f), all State residual market...

  7. 21 CFR 1301.71 - Security requirements generally.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 9 2010-04-01 2010-04-01 false Security requirements generally. 1301.71 Section 1301.71 Food and Drugs DRUG ENFORCEMENT ADMINISTRATION, DEPARTMENT OF JUSTICE REGISTRATION OF..., cooperative buying, etc.); (2) The type and form of controlled substances handled (e.g., bulk liquids or...

  8. 31 CFR 208.6 - General account requirements.

    Science.gov (United States)

    2010-07-01

    ... 31 Money and Finance: Treasury 2 2010-07-01 2010-07-01 false General account requirements. 208.6 Section 208.6 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) FISCAL SERVICE, DEPARTMENT OF THE TREASURY FINANCIAL MANAGEMENT SERVICE MANAGEMENT OF FEDERAL AGENCY...

  9. Recommended general safety requirements for nuclear power plants

    International Nuclear Information System (INIS)

    1983-06-01

    This report presents recommendations for a set of general safety requirements that could form the basis for the licensing of nuclear power plants by the Atomic Energy Control Board. In addition to a number of recommended deterministic requirements the report includes criteria for the acceptability of the design of such plants based upon the calculated probability and consequence (in terms of predicted radiation dose to members of the public) of potential fault sequences. The report also contains a historical review of nuclear safety principles and practices in Canada

  10. General characteristics of hadron production at SPEAR

    International Nuclear Information System (INIS)

    Lueth, V.

    1977-01-01

    A discussion is given of what was learned about hadron production since the discovery of the two narrow resonances psi(3095) and psi(3684). In particular, attention is payed to the difficulties related to the model dependence of the detector efficiency and effects of the heavy lepton production. Included are recent results on inclusive production of kaons, protons, and lambda hyperons and their implications for charm particle production. The parton model, the magnetic detector, total cross sections, charged multiplicity, inclusive momentum spectra, and inclusive K 0 and Λ 0 production are discussed. 42 references

  11. GENERAL CONSIDERATIONS ON REGULATIONS AND SAFETY REQUIREMENTS FOR QUADRICYCLES

    Directory of Open Access Journals (Sweden)

    Ana Pavlovic

    2015-12-01

    Full Text Available In recent years, a new class of compact vehicles has been emerging and wide-spreading all around Europe: the quadricycle. These four-wheeled motor vehicles, originally derived from motorcycles, are a small and fuel-efficient mean of transportation used in rural or urban areas as an alternative to motorbikes or city cars. In some countries, they are also endorsed by local authorities and institutions which support small and environmentally-friendly vehicles. In this paper, several general considerations on quadricycles will be provided including the vehicle classification, evolution of regulations (as homologation, driver licence, emissions, etc, technical characteristics, safety requirements, most relevant investigations, and other additional useful information (e.g. references, links. It represents an important and actual topic of investigation for designers and manufacturers considering that the new EU regulation on the approval and market surveillance of quadricycles will soon enter in force providing conclusive requirements for functional safety environmental protection of these promising vehicles.

  12. Context generalization in Drosophila visual learning requires the mushroom bodies

    Science.gov (United States)

    Liu, Li; Wolf, Reinhard; Ernst, Roman; Heisenberg, Martin

    1999-08-01

    The world is permanently changing. Laboratory experiments on learning and memory normally minimize this feature of reality, keeping all conditions except the conditioned and unconditioned stimuli as constant as possible. In the real world, however, animals need to extract from the universe of sensory signals the actual predictors of salient events by separating them from non-predictive stimuli (context). In principle, this can be achieved ifonly those sensory inputs that resemble the reinforcer in theirtemporal structure are taken as predictors. Here we study visual learning in the fly Drosophila melanogaster, using a flight simulator,, and show that memory retrieval is, indeed, partially context-independent. Moreover, we show that the mushroom bodies, which are required for olfactory but not visual or tactile learning, effectively support context generalization. In visual learning in Drosophila, it appears that a facilitating effect of context cues for memory retrieval is the default state, whereas making recall context-independent requires additional processing.

  13. General survey of applications which require actinide nuclear data

    International Nuclear Information System (INIS)

    Raman, S.

    1976-01-01

    This review paper discusses the actinide waste problem, the buildup of toxic isotopes in the fuel, the neutron activity associated with irradiated fuel, the 252 Cf buildup problem, and the production of radioisotope power sources as broad areas that require actinide cross-section data. Decay data enter into the area of radiological safety and health physics. This paper also discusses a few cross-section measurements in progress at the Oak Ridge Electron Linear Accelerator. The availability of actinide samples through the Transuranium Program at Oak Ridge is discussed in considerable detail. The present data status with respect to the various applications is reviewed along with recommendations for improving the data base

  14. An Elementary Treatment of General Inner Products

    Science.gov (United States)

    Graver, Jack E.

    2011-01-01

    A typical first course on linear algebra is usually restricted to vector spaces over the real numbers and the usual positive-definite inner product. Hence, the proof that dim(S)+ dim(S[perpendicular]) = dim("V") is not presented in a way that is generalizable to non-positive?definite inner products or to vector spaces over other fields. In this…

  15. 42 CFR 3.210 - Required disclosure of patient safety work product to the Secretary.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Required disclosure of patient safety work product... HUMAN SERVICES GENERAL PROVISIONS PATIENT SAFETY ORGANIZATIONS AND PATIENT SAFETY WORK PRODUCT Confidentiality and Privilege Protections of Patient Safety Work Product § 3.210 Required disclosure of patient...

  16. Design requirements for SRB production control system. Volume 2: System requirements and conceptual description

    Science.gov (United States)

    1981-01-01

    In the development of the business system for the SRB automated production control system, special attention had to be paid to the unique environment posed by the space shuttle. The issues posed by this environment, and the means by which they were addressed, are reviewed. The change in management philosphy which will be required as NASA switches from one-of-a-kind launches to multiple launches is discussed. The implications of the assembly process on the business system are described. These issues include multiple missions, multiple locations and facilities, maintenance and refurbishment, multiple sources, and multiple contractors. The implications of these aspects on the automated production control system are reviewed including an assessment of the six major subsystems, as well as four other subsystem. Some general system requirements which flow through the entire business system are described.

  17. Light transport and general aviation aircraft icing research requirements

    Science.gov (United States)

    Breeze, R. K.; Clark, G. M.

    1981-01-01

    A short term and a long term icing research and technology program plan was drafted for NASA LeRC based on 33 separate research items. The specific items listed resulted from a comprehensive literature search, organized and assisted by a computer management file and an industry/Government agency survey. Assessment of the current facilities and icing technology was accomplished by presenting summaries of ice sensitive components and protection methods; and assessments of penalty evaluation, the experimental data base, ice accretion prediction methods, research facilities, new protection methods, ice protection requirements, and icing instrumentation. The intent of the research plan was to determine what icing research NASA LeRC must do or sponsor to ultimately provide for increased utilization and safety of light transport and general aviation aircraft.

  18. General-Purpose Monitoring during Speech Production

    Science.gov (United States)

    Ries, Stephanie; Janssen, Niels; Dufau, Stephane; Alario, F.-Xavier; Burle, Boris

    2011-01-01

    The concept of "monitoring" refers to our ability to control our actions on-line. Monitoring involved in speech production is often described in psycholinguistic models as an inherent part of the language system. We probed the specificity of speech monitoring in two psycholinguistic experiments where electroencephalographic activities were…

  19. The Gibbs entropy production in general relativity

    International Nuclear Information System (INIS)

    Henneaux, M.

    1983-01-01

    The entropy production is analyzed in the case of homogeneous cosmological models of the Bianchi type. It is shown to vanish for class-A models and to be undefined for class-B ones, because of an ambiguity in the measure on the space of the true gravitational degrees of freedom. How this results extend to the full Einstein theory is discussed

  20. Gibbs entropy production in general relativity

    International Nuclear Information System (INIS)

    Henneaux, M.

    1983-01-01

    The entropy production is analyzed in the case of homogeneous cosmological models of the Bianchi type. It is shown to vanish for class-A models and to be undefined for class-B ones, because of an ambiguity in the measure on the space of the true gravitational degrees of freedom. How this results extends to the full Einstein theory is discussed

  1. 40 CFR 158.310 - Product chemistry data requirements table.

    Science.gov (United States)

    2010-07-01

    ... PAI TGAI or PA 9, 21 830.7300 Density/relative density/bulk density R MP and TGAI EP and TGAI 9 830... an oxidizing or reducing agent. 14. Required when the product contains combustible liquids. 15. Required when the product is potentially explosive. 16. Required when the product is an emulsifiable liquid...

  2. General productivity code: productivity optimization of gaseous diffusion cascades. The programmer's guide

    International Nuclear Information System (INIS)

    Tunstall, J.N.

    1975-05-01

    The General Productivity Code is a FORTRAN IV computer program for the IBM System 360. With its model of the productivity of gaseous diffusion cascades, the program is used to determine optimum cascade performance based on specified operating conditions and to aid in the calculation of optimum operating conditions for a complex of diffusion cascades. This documentation of the program is directed primarily to programmers who will be responsible for updating the code as requested by the users. It is also intended to be an aid in training new Productivity Code users and to serve as a general reference manual. Elements of the mathematical model, the input data requirements, the definitions of the various tasks (Instructions) that can be performed, and a detailed description of most FORTRAN variables and program subroutines are presented. A sample problem is also included. (auth)

  3. Survey of Mathematics and Science Requirements for Production-Oriented Agronomy Majors.

    Science.gov (United States)

    Aide, Michael; Terry, Danny

    1996-01-01

    Analyzes course requirements to determine the amount of required mathematics and science for production-oriented agronomy majors. Reports that mathematics requirements center around college algebra and statistics; science requirements generally include chemistry, biology, plant physiology, and genetics; and land-grant institutions have a…

  4. 9 CFR 318.17 - Requirements for the production of cooked beef, roast beef, and cooked corned beef products.

    Science.gov (United States)

    2010-01-01

    ... Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE AGENCY ORGANIZATION AND TERMINOLOGY... OFFICIAL ESTABLISHMENTS; REINSPECTION AND PREPARATION OF PRODUCTS General § 318.17 Requirements for the... must include a cooking step. Controlled intermediate step(s) applied to raw product may form part of...

  5. 46 CFR 57.06-4 - Production testing specimen requirements.

    Science.gov (United States)

    2010-10-01

    ... WELDING AND BRAZING Production Tests § 57.06-4 Production testing specimen requirements. (a) For test... 46 Shipping 2 2010-10-01 2010-10-01 false Production testing specimen requirements. 57.06-4... to welding shall not throw the finished test plate out of line by an angle of over 5°. (c) Where the...

  6. 18 CFR 292.203 - General requirements for qualification.

    Science.gov (United States)

    2010-04-01

    ... certification, pursuant to § 292.207(b)(1), that has been granted. (c) Hydroelectric small power production facilities located at a new dam or diversion. (1) A hydroelectric small power production facility that..., pursuant to § 292.207(b)(1), that has been granted. (c) Hydroelectric small power production facilities...

  7. Biomedical Requirements for High Productivity Computing Systems

    Science.gov (United States)

    2005-04-01

    differences in heart muscle structure between normal and brittle-boned mice suffering from osteogenesis imperfecta (OI) because of a deficiency in the protein...reached. In a typical comparative modeling exercise one would use a heuristic algorithm to determine possible sequences of interest, then the Smith...example exercise , require a description of the cellular events that create demands for oxygen. Having cellular level equations together with

  8. 14 CFR 61.103 - Eligibility requirements: General.

    Science.gov (United States)

    2010-01-01

    ... that the person is prepared for the required knowledge test. (e) Pass the required knowledge test on... category and class rating sought. (j) Hold a U.S. student pilot certificate, sport pilot certificate, or...

  9. 42 CFR 413.75 - Direct GME payments: General requirements.

    Science.gov (United States)

    2010-10-01

    ...-based providers for the costs of approved residency programs in medicine, osteopathy, dentistry, and... activities means the care and treatment of particular patients, including services for which a physician or..., general internal medicine, general pediatrics, preventive medicine, geriatric medicine or osteopathic...

  10. Security Requirements Management in Software Product Line Engineering

    Science.gov (United States)

    Mellado, Daniel; Fernández-Medina, Eduardo; Piattini, Mario

    Security requirements engineering is both a central task and a critical success factor in product line development due to the complexity and extensive nature of product lines. However, most of the current product line practices in requirements engineering do not adequately address security requirements engineering. Therefore, in this chapter we will propose a security requirements engineering process (SREPPLine) driven by security standards and based on a security requirements decision model along with a security variability model to manage the variability of the artefacts related to security requirements. The aim of this approach is to deal with security requirements from the early stages of the product line development in a systematic way, in order to facilitate conformance with the most relevant security standards with regard to the management of security requirements, such as ISO/IEC 27001 and ISO/IEC 15408.

  11. 18 CFR 157.6 - Applications; general requirements.

    Science.gov (United States)

    2010-04-01

    ... showing the revenue responsibility for each firm rate schedule under the pipeline's currently effective... this section requires an applicant to reveal Critical Energy Infrastructure Information (CEII), as...

  12. 14 CFR 61.153 - Eligibility requirements: General.

    Science.gov (United States)

    2010-01-01

    ... the English language. If the applicant is unable to meet one of these requirements due to medical... rating issued under this part; (2) Meet the military experience requirements under § 61.73 of this part... military pilot or former rated military pilot of an Armed Force of the United States; or (3) Holds either a...

  13. 14 CFR 61.123 - Eligibility requirements: General.

    Science.gov (United States)

    2010-01-01

    ... must: (a) Be at least 18 years of age; (b) Be able to read, speak, write, and understand the English language. If the applicant is unable to meet one of these requirements due to medical reasons, then the... who: (1) Conducted the required ground training or reviewed the person's home study on the...

  14. Predisposal management of radioactive waste. General safety requirements. Pt. 5

    International Nuclear Information System (INIS)

    2009-01-01

    The objective of this Safety Requirements publication is to establish, the requirements that must be satisfied in the predisposal management of radioactive waste. This publication sets out the objectives, criteria and requirements for the protection of human health and the environment that apply to the siting, design, construction, commissioning, operation and shutdown of facilities for the predisposal management of radioactive waste, and the requirements that must be met to ensure the safety of such facilities and activities. This Safety Requirements publication applies to the predisposal management of radioactive waste of all types and covers all the steps in its management from its generation up to its disposal, including its processing (pretreatment, treatment and conditioning), storage and transport. Such waste may arise from the commissioning, operation and decommissioning of nuclear facilities; the use of radionuclides in medicine, industry, agriculture, research and education; the processing of materials that contain naturally occurring radionuclides; and the remediation of contaminated areas. The introduction of the document (Section 1) informs about its objective, scope and structure. The protection of human health and the environment is considered in Section 2 of this publication. Section 3 establishes requirements for the responsibilities associated with the predisposal management of radioactive waste. Requirements for the principal approaches to and the elements of the predisposal management of radioactive waste are established in Section 4. Section 5 establishes requirements for the safe development and operation of predisposal radioactive waste management facilities and safe conduct of activities. The Annex presents a discussion of the consistency of the safety requirements established in this publication with the fundamental safety principles

  15. 12 CFR 226.5 - General disclosure requirements.

    Science.gov (United States)

    2010-01-01

    ... paragraph (b)(2) does not apply if the creditor is unable to meet the requirement because of an act of God, war, civil disorder, natural disaster, or strike. (3) Credit and charge card application and...

  16. 15 CFR 801.3 - General reporting requirements.

    Science.gov (United States)

    2010-01-01

    ...) BUREAU OF ECONOMIC ANALYSIS, DEPARTMENT OF COMMERCE SURVEY OF INTERNATIONAL TRADE IN SERVICES BETWEEN U.S... the U.S. Government, engaged in international trade in services. Specific reporting requirements for a...

  17. 46 CFR 310.54 - General requirements for eligibility.

    Science.gov (United States)

    2010-10-01

    ...) Nominees from foreign nations; (2) nominees from the Northern Mariana Islands; (3) designees from the Trust... candidate, as a result of the investigation, fail to meet the requirements established for appointment as...

  18. GENERAL REQUIREMENTS FOR SIMULATION MODELS IN WASTE MANAGEMENT

    International Nuclear Information System (INIS)

    Miller, Ian; Kossik, Rick; Voss, Charlie

    2003-01-01

    Most waste management activities are decided upon and carried out in a public or semi-public arena, typically involving the waste management organization, one or more regulators, and often other stakeholders and members of the public. In these environments, simulation modeling can be a powerful tool in reaching a consensus on the best path forward, but only if the models that are developed are understood and accepted by all of the parties involved. These requirements for understanding and acceptance of the models constrain the appropriate software and model development procedures that are employed. This paper discusses requirements for both simulation software and for the models that are developed using the software. Requirements for the software include transparency, accessibility, flexibility, extensibility, quality assurance, ability to do discrete and/or continuous simulation, and efficiency. Requirements for the models that are developed include traceability, transparency, credibility/validity, and quality control. The paper discusses these requirements with specific reference to the requirements for performance assessment models that are used for predicting the long-term safety of waste disposal facilities, such as the proposed Yucca Mountain repository

  19. [Precision medicine : a required approach for the general internist].

    Science.gov (United States)

    Waeber, Gérard; Cornuz, Jacques; Gaspoz, Jean-Michel; Guessous, Idris; Mooser, Vincent; Perrier, Arnaud; Simonet, Martine Louis

    2017-01-18

    The general internist cannot be a passive bystander of the anticipated medical revolution induced by precision medicine. This latter aims to improve the predictive and/or clinical course of an individual by integrating all biological, genetic, environmental, phenotypic and psychosocial knowledge of a person. In this article, national and international initiatives in the field of precision medicine are discussed as well as the potential financial, ethical and limitations of personalized medicine. The question is not to know if precision medicine will be part of everyday life but rather to integrate early the general internist in multidisciplinary teams to ensure optimal information and shared-decision process with patients and individuals.

  20. Land and Water requirements for meat production in China

    NARCIS (Netherlands)

    Zheng, Wanli

    2010-01-01

    China will face a challenge for meat production with its available land and water. The production of meat requires substantial amounts of livestock feed, which in turn require vast amounts of land and water to produce it. As China has continued to develop

  1. 14 CFR 1216.204 - General implementation requirements.

    Science.gov (United States)

    2010-01-01

    ... the general public as well as employees. These plans will include the integration of adequate warning... new authorizations or appropriations transmitted to the Office of Management and Budget shall indicate... would not impact the floodplain or wetlands. (ii) The only alternative would be to construct new...

  2. 6 CFR 5.45 - Procedure when testimony or production of documents is sought; general.

    Science.gov (United States)

    2010-01-01

    ... 6 Domestic Security 1 2010-01-01 2010-01-01 false Procedure when testimony or production of... Procedure when testimony or production of documents is sought; general. (a) If official information is... requiring oral testimony, and identification of potentially relevant documents. (c) The appropriate...

  3. Overview of contaminant arrival distributions as general evaluation requirements

    International Nuclear Information System (INIS)

    Anon.

    1977-01-01

    The environmental consequences of subsurface contamination problems can be completely and effectively evaluated by fulfilling the following five requirements: Determine each present or future outflow boundary of contaminated groundwater; provide the location/arrival-time distributions; provide the location/outflow-quantity distributions; provide these distributions for each individual chemical or biological constituent of environmental importance; and use the arrival distributions to determine the quantity and concentration of each contaminant that will interface with the environment as time passes. The arrival distributions on which these requirements are based provide a reference point for communication among scientists and public decision makers by enabling complicated scientific analyses to be presented as simple summary relationships

  4. Strength development of concrete : balancing production requirements and ecological impact

    NARCIS (Netherlands)

    Onghena, S.; Grunewald, S.; Schutter, G; Jaime C., Galvez; Aguado de Cea, Antonio; Fernandez-Ordonez, David; Sakai, Koji; Reye s, Encarnación; Casati, Maria J .; Enfedaque, Alejandro; Alberti, Marcos G.; de la Fuente, Albert

    2016-01-01

    The effective production of concrete structures requires adequate control of
    strength development in order to realise the scheduled production cycles. Demoulding of elements can take place only when sufficient strength is gained and the production cycle has to be maintained with seasonal changes

  5. 40 CFR 26.1116 - General requirements for informed consent.

    Science.gov (United States)

    2010-07-01

    ... PROTECTION OF HUMAN SUBJECTS Basic Ethical Requirements for Third-Party Human Research for Pesticides... informed consent. No investigator may involve a human being as a subject in research covered by this... subject's legal rights, or releases or appears to release the investigator, the sponsor, the institution...

  6. 21 CFR 50.23 - Exception from general requirements.

    Science.gov (United States)

    2010-04-01

    ... person directing that the specimen be collected to know, at the time the specimen was collected, that... system is capable of tracking and will be used to track the proposed treatment from supplier to the... investigator (e.g., clinical laboratory director or other responsible person), required to preserve the life of...

  7. 49 CFR 229.137 - Sanitation, general requirements.

    Science.gov (United States)

    2010-10-01

    ... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION RAILROAD LOCOMOTIVE SAFETY STANDARDS Safety Requirements Cabs and... for duty or occupying the cab for duty; and (6) Equipped with a trash receptacle, unless the railroad otherwise provides portable trash receptacles to employees upon reporting for duty or occupying the cab for...

  8. 40 CFR 92.124 - Test sequence; general requirements.

    Science.gov (United States)

    2010-07-01

    ... PROGRAMS (CONTINUED) CONTROL OF AIR POLLUTION FROM LOCOMOTIVES AND LOCOMOTIVE ENGINES Test Procedures § 92...) For the testing of locomotives and engines, the atmospheric pressure shall be between 31.0 inches Hg... test conditions. (c) No control of humidity is required for ambient air, engine intake air or dilution...

  9. 29 CFR 793.4 - General requirements for exemption.

    Science.gov (United States)

    2010-07-01

    ... AND TELEVISION STATION EMPLOYEES FROM OVERTIME PAY REQUIREMENTS UNDER SECTION 13(b)(9) OF THE FAIR... employee must be “employed as” an announcer, or a news editor, or a chief engineer. (b) The employee must be employed “by” a radio or television station. (c) The major studio of such radio or television...

  10. 17 CFR 4.24 - General disclosures required.

    Science.gov (United States)

    2010-04-01

    ... tabular format, an analysis setting forth how the break-even point for the pool was calculated. The... feature becomes operative; and (3) Disclose, in the break-even analysis required by § 4.24(i)(6), the... page number) AND A STATEMENT OF THE PERCENTAGE RETURN NECESSARY TO BREAK EVEN, THAT IS, TO RECOVER THE...

  11. 40 CFR 158.1000 - Applicator exposure-general requirements.

    Science.gov (United States)

    2010-07-01

    ... requirements. 158.1000 Section 158.1000 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED... Occupational Safety and Health Administration (OSHA), provide adequate protection from risk under FIFRA for a... and the applicator activity of concern, including formulation type, application methods and rates...

  12. 12 CFR 226.17 - General disclosure requirements.

    Science.gov (United States)

    2010-01-01

    ... mandatory compliance date of §§ 226.46, 47, and 48, the creditor need not make the following disclosures...) Form of disclosures. (1) The creditor shall make the disclosures required by this subpart clearly and... segregated from everything else, and shall not contain any information not directly related 37 to the...

  13. 47 CFR 15.319 - General technical requirements.

    Science.gov (United States)

    2010-10-01

    ...-equivalent voltage. The measurement results shall be properly adjusted for any instrument limitations, such... bandwidth, sensitivity, etc., so as to obtain a true peak measurement for the emission in question over the... point. (i) Unlicensed PCS devices are subject to the radiofrequency radiation exposure requirements...

  14. 40 CFR 725.25 - General administrative requirements.

    Science.gov (United States)

    2010-07-01

    ... SUBSTANCES CONTROL ACT REPORTING REQUIREMENTS AND REVIEW PROCESSES FOR MICROORGANISMS Administrative...: The company named in this submission intends to manufacture, import, or process for a commercial... e-PMN software must be used to print the biotechnology notice submission to be sent to EPA. Paper...

  15. 14 CFR 65.101 - Eligibility requirements: General.

    Science.gov (United States)

    2010-01-01

    ..., appropriate to the job for which he is employed; (3) Be employed for a specific job requiring those special... aircraft or components, appropriate to the job for which he is employed; (5) Have either— (i) At least 18 months of practical experience in the procedures, practices, inspection methods, materials, tools...

  16. 14 CFR 61.96 - Applicability and eligibility requirements: General.

    Science.gov (United States)

    2010-01-01

    ... certificate must: (1) Be at least 17 years of age; (2) Be able to read, speak, write, and understand the English language. If the applicant is unable to meet one of these requirements due to medical reasons... authorized instructor who— (i) Conducted the training or reviewed the applicant's home study on the...

  17. 40 CFR 63.6105 - What are my general requirements for complying with this subpart?

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 12 2010-07-01 2010-07-01 true What are my general requirements for... Turbines General Compliance Requirements § 63.6105 What are my general requirements for complying with this..., oxidation catalyst emission control device or other air pollution control equipment, and monitoring...

  18. 78 FR 38555 - Importer Permit Requirements for Tobacco Products and Processed Tobacco, and Other Requirements...

    Science.gov (United States)

    2013-06-27

    ..., and Other Requirements for Tobacco Products, Processed Tobacco, and Cigarette Papers and Tubes AGENCY... administration and enforcement of importer permits over the past decade, TTB believes that it can gain... minimum manufacturing and marking requirements for tobacco products and cigarette papers and tubes, and...

  19. Leadership and Management for Safety. General Safety Requirements (Spanish Edition)

    International Nuclear Information System (INIS)

    2017-01-01

    his Safety Requirements publication establishes requirements that support Principle 3 of the Fundamental Safety Principles in relation to establishing, sustaining and continuously improving leadership and management for safety and an integrated management system. It emphasizes that leadership for safety, management for safety, an effective management system and a systemic approach (i.e. an approach in which interactions between technical, human and organizational factors are duly considered) are all essential to the specification and application of adequate safety measures and to the fostering of a strong safety culture. Leadership and an effective management system will integrate safety, health, environmental, security, quality, human-and-organizational factors, societal and economic elements. The management system will ensure the fostering of a strong safety culture, regular assessment of performance and the application of lessons from experience. The publication is intended for use by regulatory bodies, operating organizations and other organizations concerned with facilities and activities that give rise to radiation risks.

  20. Decommissioning of Facilities. General Safety Requirements. Pt. 6

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2014-07-15

    Decommissioning is the last step in the lifetime management of a facility. It must also be considered during the design, construction, commissioning and operation of facilities. This publication establishes requirements for the safe decommissioning of a broad range of facilities: nuclear power plants, research reactors, nuclear fuel cycle facilities, facilities for processing naturally occurring radioactive material, former military sites, and relevant medical, industrial and research facilities. It addresses all the aspects of decommissioning that are required to ensure safety, aspects such as roles and responsibilities, strategy and planning for decommissioning, conduct of decommissioning actions and termination of the authorization for decommissioning. It is intended for use by those involved in policy development, regulatory control and implementation of decommissioning.

  1. Leadership and Management for Safety. General Safety Requirements (French Edition)

    International Nuclear Information System (INIS)

    2016-01-01

    This Safety Requirements publication establishes requirements that support Principle 3 of the Fundamental Safety Principles in relation to establishing, sustaining and continuously improving leadership and management for safety and an integrated management system. It emphasizes that leadership for safety, management for safety, an effective management system and a systemic approach (i.e. an approach in which interactions between technical, human and organizational factors are duly considered) are all essential to the specification and application of adequate safety measures and to the fostering of a strong safety culture. Leadership and an effective management system will integrate safety, health, environmental, security, quality, human-and-organizational factors, societal and economic elements. The management system will ensure the fostering of a strong safety culture, regular assessment of performance and the application of lessons from experience. The publication is intended for use by regulatory bodies, operating organizations and other organizations concerned with facilities and activities that give rise to radiation risks.

  2. Leadership and Management for Safety. General Safety Requirements (Arabic Edition)

    International Nuclear Information System (INIS)

    2016-01-01

    This Safety Requirements publication establishes requirements that support Principle 3 of the Fundamental Safety Principles in relation to establishing, sustaining and continuously improving leadership and management for safety and an integrated management system. It emphasizes that leadership for safety, management for safety, an effective management system and a systemic approach (i.e. an approach in which interactions between technical, human and organizational factors are duly considered) are all essential to the specification and application of adequate safety measures and to the fostering of a strong safety culture. Leadership and an effective management system will integrate safety, health, environmental, security, quality, human-and-organizational factors, societal and economic elements. The management system will ensure the fostering of a strong safety culture, regular assessment of performance and the application of lessons from experience. The publication is intended for use by regulatory bodies, operating organizations and other organizations concerned with facilities and activities that give rise to radiation risks.

  3. Leadership and Management for Safety. General Safety Requirements (Chinese Edition)

    International Nuclear Information System (INIS)

    2016-01-01

    This Safety Requirements publication establishes requirements that support Principle 3 of the Fundamental Safety Principles in relation to establishing, sustaining and continuously improving leadership and management for safety and an integrated management system. It emphasizes that leadership for safety, management for safety, an effective management system and a systemic approach (i.e. an approach in which interactions between technical, human and organizational factors are duly considered) are all essential to the specification and application of adequate safety measures and to the fostering of a strong safety culture. Leadership and an effective management system will integrate safety, health, environmental, security, quality, human-and-organizational factors, societal and economic elements. The management system will ensure the fostering of a strong safety culture, regular assessment of performance and the application of lessons from experience. The publication is intended for use by regulatory bodies, operating organizations and other organizations concerned with facilities and activities that give rise to radiation risks.

  4. Leadership and Management for Safety. General Safety Requirements

    International Nuclear Information System (INIS)

    2016-01-01

    This Safety Requirements publication establishes requirements that support Principle 3 of the Fundamental Safety Principles in relation to establishing, sustaining and continuously improving leadership and management for safety and an integrated management system. It emphasizes that leadership for safety, management for safety, an effective management system and a systemic approach (i.e. an approach in which interactions between technical, human and organizational factors are duly considered) are all essential to the specification and application of adequate safety measures and to the fostering of a strong safety culture. Leadership and an effective management system will integrate safety, health, environmental, security, quality, human-and-organizational factor, societal and economic elements. The management system will ensure the fostering of a strong safety culture, regular assessment of performance and the application of lessons from experience. The publication is intended for use by regulatory bodies, operating organizations (registrants and licensees) and other organizations concerned with facilities and activities that give rise to radiation risks

  5. Predisposal Management of Radioactive Waste. General Safety Requirements Pt. 5

    International Nuclear Information System (INIS)

    2010-01-01

    There are a large number of facilities and activities around the world in which radioactive material is produced, handled and stored. This Safety Requirements publication presents international consensus requirements for the management of radioactive waste prior to its disposal. It provides the safety imperatives on the basis of which facilities can be designed, operated and regulated. The publication is supported by a number of Safety Guides that provide up to date recommendations and guidance on best practices for management of particular types of radioactive waste, for storage of radioactive waste, for assuring safety by developing safety cases and supporting safety assessments, and for applying appropriate management systems. Contents: 1. Introduction; 2. Protection of human health and the environment; 3. Responsibilities associated with the predisposal management of radioactive waste; 4. Steps in the predisposal management of radioactive waste; 5. Development and operation of predisposal radioactive waste management facilities and activities; Annex: Predisposal management of radioactive waste and the fundamental safety principles.

  6. Decommissioning of Facilities. General Safety Requirements. Pt. 6 (Spanish Edition)

    International Nuclear Information System (INIS)

    2017-01-01

    Decommissioning is the last step in the lifetime management of a facility. It must also be considered during the design, construction, commissioning and operation of facilities. This publication establishes requirements for the safe decommissioning of a broad range of facilities: nuclear power plants, research reactors, nuclear fuel cycle facilities, facilities for processing naturally occurring radioactive material, former military sites, and relevant medical, industrial and research facilities. It addresses all the aspects of decommissioning that are required to ensure safety, aspects such as roles and responsibilities, strategy and planning for decommissioning, conduct of decommissioning actions and termination of the authorization for decommissioning. It is intended for use by those involved in policy development, regulatory control and implementation of decommissioning.

  7. Decommissioning of Facilities. General Safety Requirements. Pt. 6 (Russian Edition)

    International Nuclear Information System (INIS)

    2015-01-01

    Decommissioning is the last step in the lifetime management of a facility. It must also be considered during the design, construction, commissioning and operation of facilities. This publication establishes requirements for the safe decommissioning of a broad range of facilities: nuclear power plants, research reactors, nuclear fuel cycle facilities, facilities for processing naturally occurring radioactive material, former military sites, and relevant medical, industrial and research facilities. It addresses all the aspects of decommissioning that are required to ensure safety, aspects such as roles and responsibilities, strategy and planning for decommissioning, conduct of decommissioning actions and termination of the authorization for decommissioning. It is intended for use by those involved in policy development, regulatory control and implementation of decommissioning

  8. Predisposal Management of Radioactive Waste. General Safety Requirements Pt. 5

    International Nuclear Information System (INIS)

    2009-01-01

    There are a large number of facilities and activities around the world in which radioactive material is produced, handled and stored. This Safety Requirements publication presents international consensus requirements for the management of radioactive waste prior to its disposal. It provides the safety imperatives on the basis of which facilities can be designed, operated and regulated. The publication is supported by a number of Safety Guides that provide up to date recommendations and guidance on best practices for management of particular types of radioactive waste, for storage of radioactive waste, for assuring safety by developing safety cases and supporting safety assessments, and for applying appropriate management systems. Contents: 1. Introduction; 2. Protection of human health and the environment; 3. Responsibilities associated with the predisposal management of radioactive waste; 4. Steps in the predisposal management of radioactive waste; 5. Development and operation of predisposal radioactive waste management facilities and activities; Annex: Predisposal management of radioactive waste and the fundamental safety principles.

  9. Transforming Multidisciplinary Customer Requirements to Product Design Specifications

    Science.gov (United States)

    Ma, Xiao-Jie; Ding, Guo-Fu; Qin, Sheng-Feng; Li, Rong; Yan, Kai-Yin; Xiao, Shou-Ne; Yang, Guang-Wu

    2017-09-01

    With the increasing of complexity of complex mechatronic products, it is necessary to involve multidisciplinary design teams, thus, the traditional customer requirements modeling for a single discipline team becomes difficult to be applied in a multidisciplinary team and project since team members with various disciplinary backgrounds may have different interpretations of the customers' requirements. A new synthesized multidisciplinary customer requirements modeling method is provided for obtaining and describing the common understanding of customer requirements (CRs) and more importantly transferring them into a detailed and accurate product design specifications (PDS) to interact with different team members effectively. A case study of designing a high speed train verifies the rationality and feasibility of the proposed multidisciplinary requirement modeling method for complex mechatronic product development. This proposed research offersthe instruction to realize the customer-driven personalized customization of complex mechatronic product.

  10. A Generalized Cauchy Distribution Framework for Problems Requiring Robust Behavior

    Directory of Open Access Journals (Sweden)

    Carrillo RafaelE

    2010-01-01

    Full Text Available Statistical modeling is at the heart of many engineering problems. The importance of statistical modeling emanates not only from the desire to accurately characterize stochastic events, but also from the fact that distributions are the central models utilized to derive sample processing theories and methods. The generalized Cauchy distribution (GCD family has a closed-form pdf expression across the whole family as well as algebraic tails, which makes it suitable for modeling many real-life impulsive processes. This paper develops a GCD theory-based approach that allows challenging problems to be formulated in a robust fashion. Notably, the proposed framework subsumes generalized Gaussian distribution (GGD family-based developments, thereby guaranteeing performance improvements over traditional GCD-based problem formulation techniques. This robust framework can be adapted to a variety of applications in signal processing. As examples, we formulate four practical applications under this framework: (1 filtering for power line communications, (2 estimation in sensor networks with noisy channels, (3 reconstruction methods for compressed sensing, and (4 fuzzy clustering.

  11. Evolution of general design requirements for french pressurized water reactors

    International Nuclear Information System (INIS)

    Gros, G.; Jalouneix, J.; Rollinger, F.

    1988-10-01

    The design of French pressurized water reactors is based first on deterministic principles, using the well-known defense in depth concept. This safety approach, basically reflected current American practice at that time, which consisted notably in designing engineered safeguard systems capable of limiting the consequences of accidents assumed to be credible despite the preventive measures taken. Further reflections have led to complete this approach, resulting in modifications to regulatory practice, mainly related to better practical assimilation of the problems arising during plant unit operation and reactor control after an accident and to the determination to enhance the overall consistency of the safety approach. As regards system redundancy, it should be noted that common cause failures can result in the total loss of a redundant system. System redundancy aspects will be dealt with in Chapter 2. As regards study of design basis accidents, attention was focused on the human intervention stage following automatic activation of protection and safeguard systems. This resulted, for all plant units, in the revision of operating procedures, accompanied by examination of the means required for their implementation. These subjects will be discussed in Chapter 3. Finally, as regards equipment classification, the range of equipment subjected to particular requirements, formerly limited to design basis safety classified equipment, was enlarged to include important for safety equipment. This subject will be dealt with in Chapter 5

  12. Visual short-term memory always requires general attention.

    Science.gov (United States)

    Morey, Candice C; Bieler, Malte

    2013-02-01

    The role of attention in visual memory remains controversial; while some evidence has suggested that memory for binding between features demands no more attention than does memory for the same features, other evidence has indicated cognitive costs or mnemonic benefits for explicitly attending to bindings. We attempted to reconcile these findings by examining how memory for binding, for features, and for features during binding is affected by a concurrent attention-demanding task. We demonstrated that performing a concurrent task impairs memory for as few as two visual objects, regardless of whether each object includes one or more features. We argue that this pattern of results reflects an essential role for domain-general attention in visual memory, regardless of the simplicity of the to-be-remembered stimuli. We then discuss the implications of these findings for theories of visual working memory.

  13. 76 FR 22030 - Third Party Testing for Certain Children's Products; Toddler Beds: Requirements for Accreditation...

    Science.gov (United States)

    2011-04-20

    ... and content of the ILAC-MRA approach and of the requirements of the ISO/IEC 17025:2005 laboratory... to ISO Standard ISO/IEC 17025:2005, ``General Requirements for the Competence of Testing and.... The product \\1\\ was tested by a third party conformity assessment body that was ISO/IEC 17025...

  14. 76 FR 49286 - Third Party Testing for Certain Children's Products; Notice of Requirements for Accreditation of...

    Science.gov (United States)

    2011-08-10

    ... history and content of the ILAC-MRA approach and of the requirements of the ISO/IEC 17025:2005 laboratory... be to ISO Standard ISO/IEC 17025:2005, ``General Requirements for the Competence of Testing and..., the product was tested by a third party conformity assessment body that was ISO/IEC 17025 accredited...

  15. Polymorphic Uncertain Linear Programming for Generalized Production Planning Problems

    Directory of Open Access Journals (Sweden)

    Xinbo Zhang

    2014-01-01

    Full Text Available A polymorphic uncertain linear programming (PULP model is constructed to formulate a class of generalized production planning problems. In accordance with the practical environment, some factors such as the consumption of raw material, the limitation of resource and the demand of product are incorporated into the model as parameters of interval and fuzzy subsets, respectively. Based on the theory of fuzzy interval program and the modified possibility degree for the order of interval numbers, a deterministic equivalent formulation for this model is derived such that a robust solution for the uncertain optimization problem is obtained. Case study indicates that the constructed model and the proposed solution are useful to search for an optimal production plan for the polymorphic uncertain generalized production planning problems.

  16. Six-term exact sequences for smooth generalized crossed products

    DEFF Research Database (Denmark)

    Gabriel, Olivier; Grensing, Martin

    2013-01-01

    We define smooth generalized crossed products and prove six-term exact sequences of Pimsner–Voiculescu type. This sequence may, in particular, be applied to smooth subalgebras of the quantum Heisenberg manifolds in order to compute the generators of their cyclic cohomology. Further, our results...... include the known results for smooth crossed products. Our proof is based on a combination of arguments from the setting of (Cuntz–)Pimsner algebras and the Toeplitz proof of Bott periodicity....

  17. 29 CFR 1977.3 - General requirements of section 11(c) of the Act.

    Science.gov (United States)

    2010-07-01

    ... WILLIAMS-STEIGER OCCUPATIONAL SAFETY AND HEALTH ACT OF 1970 General § 1977.3 General requirements of... 29 Labor 9 2010-07-01 2010-07-01 false General requirements of section 11(c) of the Act. 1977.3 Section 1977.3 Labor Regulations Relating to Labor (Continued) OCCUPATIONAL SAFETY AND HEALTH...

  18. Structuring Formal Requirements Specifications for Reuse and Product Families

    Science.gov (United States)

    Heimdahl, Mats P. E.

    2001-01-01

    In this project we have investigated how formal specifications should be structured to allow for requirements reuse, product family engineering, and ease of requirements change, The contributions of this work include (1) a requirements specification methodology specifically targeted for critical avionics applications, (2) guidelines for how to structure state-based specifications to facilitate ease of change and reuse, and (3) examples from the avionics domain demonstrating the proposed approach.

  19. Arithmetical and geometrical means of generalized logarithmic and exponential functions: Generalized sum and product operators

    International Nuclear Information System (INIS)

    Arruda, Tiago Jose; Silva Gonzalez, Rodrigo; Sangaletti Tercariol, Cesar Augusto; Souto Martinez, Alexandre

    2008-01-01

    One-parameter generalizations of the logarithmic and exponential functions have been obtained as well as algebraic operators to retrieve extensivity. Analytical expressions for the successive applications of the sum or product operators on several values of a variable are obtained here. Applications of the above formalism are considered

  20. The Deployment of Product-Related Environmental Legislation into Product Requirements

    Directory of Open Access Journals (Sweden)

    Daniela C. A. Pigosso

    2016-04-01

    Full Text Available Environmental legislation is increasingly changing its focus from manufacturing-oriented to product-oriented instruments. Compliance with product-related environmental legislation is achieved by the incorporation of environmental requirements into the early phases of the product development process (PDP. Nevertheless, the deployment of product-related environmental legislation into product requirements is still a challenge. This study followed an inductive approach to propose a guideline to support the identification, analysis and deployment of product requirements based on product-related environmental legislation. The guideline is composed of nine steps, clustered into three groups according to their main objective: (A identification of environmental product-related legislation; (B identification of legislative topics to be considered for the deployment of requirements; and (C creation and validation of product requirements. The product requirements deployed are to be considered during the PDP. The guideline was evaluated in an expert consultation in a large manufacturing company, suggesting that it can be used to support the systematization and deployment of product-related environmental requirements.

  1. 46 CFR 32.75-5 - Hull requirements; general-TB/ALL.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 1 2010-10-01 2010-10-01 false Hull requirements; general-TB/ALL. 32.75-5 Section 32.75..., AND HULL REQUIREMENTS Hull Requirements for Wood Hull Tank Vessels Constructed Prior to November 10, 1936 § 32.75-5 Hull requirements; general—TB/ALL. The scantlings, material, and workmanship, and the...

  2. 46 CFR 32.70-5 - Hull requirements; general-TB/ALL.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 1 2010-10-01 2010-10-01 false Hull requirements; general-TB/ALL. 32.70-5 Section 32.70..., AND HULL REQUIREMENTS Hull Requirements for Steel Hull Tank Vessels Constructed Prior to November 10, 1936 § 32.70-5 Hull requirements; general—TB/ALL. The scantlings, material, and workmanship, the...

  3. General review of quality assurance system requirements. The utility or customer requirement

    International Nuclear Information System (INIS)

    Fowler, J.L.

    1976-01-01

    What are the customer's Quality Assurance requirements and how does he convey these to his contractor, or apply them to himself. Many documents have been prepared mostly by countries with high technology availability and it is significant to note that many of the documents, particularly those of the United States of America, were prepared for nuclear safety related plant, but the logic of these documents equally applied to heavy engineering projects that are cost effective, and this is the current thinking and practice within the CEGB (Central Electricity Generating Board). Some documents have legislative backing, others rely on contractual disciplines, but they all appear to repeat the same basic requirements, so why does one continue to write more documents. The basic problem is that customers have to satisfy differing national legislative, economic and commercial requirements and, like all discerning customers, wish to reserve the right to satisfy their own needs, which are very often highly specialized. The CEGB are aware of this problem and are actively co-operating with most of the national and international authorities who are leading in this field, with a view to obtaining compatibility of requirements, but now there still remains the problem of satisfying national custom and practice. (author)

  4. Geosensors to Support Crop Production: Current Applications and User Requirements

    Directory of Open Access Journals (Sweden)

    Lammert Kooistra

    2011-06-01

    Full Text Available Sensor technology, which benefits from high temporal measuring resolution, real-time data transfer and high spatial resolution of sensor data that shows in-field variations, has the potential to provide added value for crop production. The present paper explores how sensors and sensor networks have been utilised in the crop production process and what their added-value and the main bottlenecks are from the perspective of users. The focus is on sensor based applications and on requirements that users pose for them. Literature and two use cases were reviewed and applications were classified according to the crop production process: sensing of growth conditions, fertilising, irrigation, plant protection, harvesting and fleet control. The potential of sensor technology was widely acknowledged along the crop production chain. Users of the sensors require easy-to-use and reliable applications that are actionable in crop production at reasonable costs. The challenges are to develop sensor technology, data interoperability and management tools as well as data and measurement services in a way that requirements can be met, and potential benefits and added value can be realized in the farms in terms of higher yields, improved quality of yields, decreased input costs and production risks, and less work time and load.

  5. Generalized Enhanced Multivariance Product Representation for Data Partitioning: Constancy Level

    International Nuclear Information System (INIS)

    Tunga, M. Alper; Demiralp, Metin

    2011-01-01

    Enhanced Multivariance Product Representation (EMPR) method is used to represent multivariate functions in terms of less-variate structures. The EMPR method extends the HDMR expansion by inserting some additional support functions to increase the quality of the approximants obtained for dominantly or purely multiplicative analytical structures. This work aims to develop the generalized form of the EMPR method to be used in multivariate data partitioning approaches. For this purpose, the Generalized HDMR philosophy is taken into consideration to construct the details of the Generalized EMPR at constancy level as the introductory steps and encouraging results are obtained in data partitioning problems by using our new method. In addition, to examine this performance, a number of numerical implementations with concluding remarks are given at the end of this paper.

  6. 30 CFR 57.13001 - General requirements for boilers and pressure vessels.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false General requirements for boilers and pressure... NONMETAL MINES Compressed Air and Boilers § 57.13001 General requirements for boilers and pressure vessels. All boilers and pressure vessels shall be constructed, installed, and maintained in accordance with...

  7. 30 CFR 56.13001 - General requirements for boilers and pressure vessels.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false General requirements for boilers and pressure... MINES Compressed Air and Boilers § 56.13001 General requirements for boilers and pressure vessels. All boilers and pressure vessels shall be constructed, installed, and maintained in accordance with the...

  8. 40 CFR 60.4120 - General Hg budget trading program permit requirements.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 6 2010-07-01 2010-07-01 false General Hg budget trading program... and Compliance Times for Coal-Fired Electric Steam Generating Units Permits § 60.4120 General Hg budget trading program permit requirements. (a) For each Hg Budget source required to have a title V...

  9. User oriented definition of product requirements within mechatronic engineering

    OpenAIRE

    Gerst, M.;Gierhardt, H.;Braun, T.

    2017-01-01

    In this paper the application of a modeling technique from software engineering to mechatronic engineering is presented. The Unified Modeling Language (UML) is used to model users´ needs and relate them to product requirements. Within a bus seat development project a Use Case Model and an Analyses Model were elaborated. Advantages and Disadvantages of the presented procedure are shown.

  10. Global Water Availability and Requirements for Future Food Production

    NARCIS (Netherlands)

    Gerten, D.; Heinke, J.; Hoff, H.; Biemans, H.; Fader, M.; Waha, K.

    2011-01-01

    This study compares, spatially explicitly and at global scale, per capita water availability and water requirements for food production presently (1971-2000) and in the future given climate and population change (2070-99). A vegetation and hydrology model Lund-Potsdam-Jena managed Land (LPJmL) was

  11. REQUIREMENTS ON CLINICAL TRIALS FOR VETERINARY PHARMACEUTICAL PRODUCTS FOR FISH

    Directory of Open Access Journals (Sweden)

    Simona Sturzu

    2016-12-01

    Full Text Available Veterinary pharmaceutical products intended for use in fish should comply with all usual requirements regarding approval for marketing, according to the Order of the President of the National Sanitary Veterinary Agency and for Food Safety No.187/2007, with subsequent amendments and additions. According to the legislation the technical file should containe documentation of quality, safety of animals, consumer, user and environment and demonstration of efficacy and tolerance in the target species. This paper provides the important information on requirements for demonstration on efficacy of pharmaceutical products indended for use in fish. The principal aim of the efficacy data is to prove the therapeutic value of pharmaceutical products and to establish an optimal dose and period of dose administration. In efficacity clinical trial is needed, also, to take into account, the various conditions such as climatic aspects, disease situation, water temperature and salinity, because these may influence the outcome and veracity of the studies.

  12. Generalization of binary tensor product schemes depends upon four parameters

    International Nuclear Information System (INIS)

    Bashir, R.; Bari, M.; Mustafa, G.

    2018-01-01

    This article deals with general formulae of parametric and non parametric bivariate subdivision scheme with four parameters. By assigning specific values to those parameters we get some special cases of existing tensor product schemes as well as a new proposed scheme. The behavior of schemes produced by the general formulae is interpolating, approximating and relaxed. Approximating bivariate subdivision schemes produce some other surfaces as compared to interpolating bivariate subdivision schemes. Polynomial reproduction and polynomial generation are desirable properties of subdivision schemes. Capability of polynomial reproduction and polynomial generation is strongly connected with smoothness, sum rules, convergence and approximation order. We also calculate the polynomial generation and polynomial reproduction of 9-point bivariate approximating subdivision scheme. Comparison of polynomial reproduction, polynomial generation and continuity of existing and proposed schemes has also been established. Some numerical examples are also presented to show the behavior of bivariate schemes. (author)

  13. 9 CFR 113.200 - General requirements for killed virus vaccines.

    Science.gov (United States)

    2010-01-01

    ... completed product from each serial shall be tested for safety in guinea pigs as prescribed in § 113.38 and... an applicable Standard Requirement or in the filed Outline of Production, a killed virus vaccine.... Suitable tests to assure complete inactivation shall be written into the filed Outline of Production. (b...

  14. Energy requirement and economic analysis of citrus production in Turkey

    Energy Technology Data Exchange (ETDEWEB)

    Ozkan, Burhan E-mail: bozkan@akdeniz.edu.tr; Akcaoz, Handan; Karadeniz, Feyza

    2004-07-01

    The aim of this research was to examine the energy requirements of the inputs and output in citrus production in the Antalya province of Turkey. Data for the production of citrus fruits (orange, lemon and mandarin) were collected from 105 citrus farms by using a face to face questionnaire method. The research results revealed that lemon production was the most energy intensive among the three fruits investigated. The energy input of chemical fertilizer (49.68%), mainly nitrogen, has the biggest share in the total energy inputs followed by Diesel (30.79%). The lemon production consumed a total of 62 977.87 MJ/ha followed by orange and mandarin with 60 949.69 and 48 838.17 MJ/ha, respectively. The energy ratios for orange, mandarin and lemon were estimated to be 1.25, 1.17 and 1.06, respectively. On average, the non-renewable form of energy input was 95.90% of the total energy input used in citrus production compared to only 3.74% for the renewable form. The benefit-cost ratio was the highest in orange production (2.37) followed by lemon. The results indicate that orange production in the research area is most remunerative to growers compared to lemon and mandarin.

  15. A general enantioselective route to the chamigrene natural product family

    KAUST Repository

    White, David E.

    2010-06-01

    Described in this report is an enantioselective route toward the chamigrene natural product family. The key disconnections in our synthetic approach include sequential enantioselective decarboxylative allylation and ring-closing olefin metathesis to form the all-carbon quaternary stereocenter and spirocyclic core present in all members of this class of compounds. The generality of this strategy is demonstrated by the first total syntheses of elatol and the proposed structure of laurencenone B, as well as the first enantioselective total syntheses of laurencenone C and α-chamigrene. A brief exploration of the substrate scope of the enantioselective decarboxylative allylation/ring-closing metathesis sequence with fully substituted vinyl chlorides is also presented.

  16. A general enantioselective route to the chamigrene natural product family

    KAUST Repository

    White, David E.; Stewart, Ian C.; Seashore-Ludlow, Brinton A.; Grubbs, Robert H.; Stoltz, Brian M.

    2010-01-01

    Described in this report is an enantioselective route toward the chamigrene natural product family. The key disconnections in our synthetic approach include sequential enantioselective decarboxylative allylation and ring-closing olefin metathesis to form the all-carbon quaternary stereocenter and spirocyclic core present in all members of this class of compounds. The generality of this strategy is demonstrated by the first total syntheses of elatol and the proposed structure of laurencenone B, as well as the first enantioselective total syntheses of laurencenone C and α-chamigrene. A brief exploration of the substrate scope of the enantioselective decarboxylative allylation/ring-closing metathesis sequence with fully substituted vinyl chlorides is also presented.

  17. Pricing Participating Products under a Generalized Jump-Diffusion Model

    Directory of Open Access Journals (Sweden)

    Tak Kuen Siu

    2008-01-01

    Full Text Available We propose a model for valuing participating life insurance products under a generalized jump-diffusion model with a Markov-switching compensator. It also nests a number of important and popular models in finance, including the classes of jump-diffusion models and Markovian regime-switching models. The Esscher transform is employed to determine an equivalent martingale measure. Simulation experiments are conducted to illustrate the practical implementation of the model and to highlight some features that can be obtained from our model.

  18. Generalized infimum and sequential product of quantum effects

    International Nuclear Information System (INIS)

    Li Yuan; Sun Xiuhong; Chen Zhengli

    2007-01-01

    The quantum effects for a physical system can be described by the set E(H) of positive operators on a complex Hilbert space H that are bounded above by the identity operator I. For A, B(set-membership sign)E(H), the operation of sequential product A(convolution sign)B=A 1/2 BA 1/2 was proposed as a model for sequential quantum measurements. A nice investigation of properties of the sequential product has been carried over [Gudder, S. and Nagy, G., 'Sequential quantum measurements', J. Math. Phys. 42, 5212 (2001)]. In this note, we extend some results of this reference. In particular, a gap in the proof of Theorem 3.2 in this reference is overcome. In addition, some properties of generalized infimum A sqcap B are studied

  19. TRIGA International - History of Training Research Isotope production General Atomics

    International Nuclear Information System (INIS)

    2008-01-01

    TRIGA conceived at GA in 1956 by a distinguished group of scientists including Edward Teller and Freeman Dyson. First TRIGA reactor Mk-1 was commissioned on 3 may 1958 at G.A. Characteristic feature of TRIGA reactors is inherent safety: Sitting can be confinement or conventional building. TRIGA reactors are the most prevalent in the world: 67 reactors in 24 countries. Steady state powers up to 14 MWt, pulsing up to 22,000 MWt. To enlarge the scope of its manufactured products, CERCA engaged in a Joint Venture with General Atomics, and in July 1995 a new Company was founded: TRIGA INTERNATIONAL SAS (50% GA, 50% CERCA; Head Office: Paris (France); Sales offices: GA San Diego (Ca, USA) and CERCA Lyon (France); Manufacturing plant: CERCA Romans. General Atomics ID: founded in 1955 at San Diego, California, by General Dynamics; status: Privately held corporation; owners: Neal and Linden Blue; business: High technology research, design, manufacturing, and production for industry and Government in the U.S. and overseas; locations: U.S., Germany, Japan, Australia, Thailand, Morocco; employees: 5,000. TRIGA's ID: CERCA is a subsidiary of AREVA, born in November 05, 1957. Activities: fuel manufacture for research reactor, equipment and components for high-energy physics, radioactive sources and reference sources; plants locations: Romans and Pierrelatte (France); total strength: 180. Since the last five years TRIGA has manufactured and delivered more than 800 fuel elements with a door to door service. TRIGA International has the experience to manufacture all types of TRIGA fuel: standard fuel elements, instrumented fuel elements, fuel followed control rods, geometry: 37.3 mm (1.47 in.), 35.8 mm (1.4 in), 13 mm (0.5 in), chemical Composition: U w% 8.5, 12, 20, 30 and 45 w/o, erbium and no erbium. TRIGA International is on INL's approved vendor list (ISO 9000/NQA) and is ready to meet any TRIGA fuel needs either in the US or worldwide

  20. General requirements for pressure-retaining systems and components in CANDU nuclear power plants

    International Nuclear Information System (INIS)

    1991-11-01

    This standard specifies the general requirements for the design, fabrication and installation of pressure-retaining systems, components, and their supports in CANDU nuclear power plants. (16 figs., 2 tabs., 25 refs.)

  1. Old waste products - new requirements. Preparations for the later repository

    International Nuclear Information System (INIS)

    Graf, A.; Merx, H.

    2003-01-01

    For more than 30 years now, the Hauptabteilung Dekontaminationsbetriebe (HDB, Central Decontamination Department) of the Forschungszentrum Karlsruhe has been engaged in the management of radioactive wastes produced by the operation and decommissioning of research reactors and institutes of the Research Center, the Karlsruhe reprocessing plant, the European Institute for Transuranium Elements, and the Baden-Wuerttemberg state collection center. For this purpose, the wastes delivered to HDB have been conditioned at various facilities according to the requirements specified. These conditioning requirements, however, have changed in the course of time. In the past, only minimum declaration and conditioning requirements had to be fulfilled for the ASSE repository storage facility. Since 1994, the KONRAD repository storage conditions have been adopted. They comprise a variety of quality criteria. Judging from today, duration of interim storage until transfer to a repository storage facility will take another 30 years at least. In addition to the documentary qualification of the waste products, it is therefore required to take measures to ensure long-term safety of both the waste packages and their storage. This is why the HDB, in agreement with the supervisory authority, i.e. the Federal Radiation Protection Authority, and its experts, has decided to put the waste products into KONRAD containers in certified compliance with the repository storage conditions and to backfill these containers with concrete in accordance with approved procedures. Thus, waste packages suited for repository storage will be produced and corrosion processes and the possible release of radioactivity will be prevented. (orig.)

  2. Old waste products - new requirements. Preparations for the later repository

    Energy Technology Data Exchange (ETDEWEB)

    Graf, A.; Merx, H. [Forschungszentrum Karlsruhe GmbH Technik und Umwelt (Germany). Hauptabteilung Dekontaminationsbetriebe

    2003-07-01

    For more than 30 years now, the Hauptabteilung Dekontaminationsbetriebe (HDB, Central Decontamination Department) of the Forschungszentrum Karlsruhe has been engaged in the management of radioactive wastes produced by the operation and decommissioning of research reactors and institutes of the Research Center, the Karlsruhe reprocessing plant, the European Institute for Transuranium Elements, and the Baden-Wuerttemberg state collection center. For this purpose, the wastes delivered to HDB have been conditioned at various facilities according to the requirements specified. These conditioning requirements, however, have changed in the course of time. In the past, only minimum declaration and conditioning requirements had to be fulfilled for the ASSE repository storage facility. Since 1994, the KONRAD repository storage conditions have been adopted. They comprise a variety of quality criteria. Judging from today, duration of interim storage until transfer to a repository storage facility will take another 30 years at least. In addition to the documentary qualification of the waste products, it is therefore required to take measures to ensure long-term safety of both the waste packages and their storage. This is why the HDB, in agreement with the supervisory authority, i.e. the Federal Radiation Protection Authority, and its experts, has decided to put the waste products into KONRAD containers in certified compliance with the repository storage conditions and to backfill these containers with concrete in accordance with approved procedures. Thus, waste packages suited for repository storage will be produced and corrosion processes and the possible release of radioactivity will be prevented. (orig.)

  3. Factorial estimation of energy requirement for egg production

    DEFF Research Database (Denmark)

    Chwalibog, André

    1992-01-01

    Based on balance and respiration measurements with 60 White Leghorns during the laying period from 27 to 48 wk of age, a factorial method for estimating the energy requirement for egg production is proposed. The present experiment showed that the deposition of fat and energy increased during...... the laying period, but protein deposition slightly decreased. It has been shown that the efficiency of ME utilization for fat energy deposition is higher than for protein energy deposition in the egg. Because the proportions of protein and fat differ during the laying period, and because energy utilization...... is different between protein and fat, the ME requirement was calculated as the sum of ME for maintenance and the partial requirements for protein, fat, and carbohydrate deposition. For practical applications, functions for prediction of protein (OP), fat (OF), and energy (OE) in eggs during the laying period...

  4. Guide for preparing annual reports on radiation-safety testing of electronic products (general)

    International Nuclear Information System (INIS)

    1987-10-01

    For manufacturers of electronic products other than those for which a specific guide has been issued, the guide replaces the Guide for the Filing of Annual Reports (21 CFR Subchapter J, Section 1002.11), HHS Publication FDA 82-8127. The electronic product (general) annual reporting guide is applicable to the following products: products intended to produce x radiation (accelerators, analytical devices, therapy x-ray machines); microwave diathermy machines; cold-cathode discharge tubes; and vacuum switches and tubes operating at or above 15,000 volts. To carry out its responsibilities under Public Law 90-602, the Food and Drug Administration's Center for Devices and Radiological Health (CDRH) has issued a series of regulations contained in Title 21 of the Code of Federal Regulations (CFR). Part 1002 of 21 CFR deals with records and reports. Section 1002.61 categorizes electronic products into Groups A through C. Section 1002.30 requires manufacturers of products in Groups B and C to establish and maintain certain records, while Section 1002.11 requires such manufacturers to submit an Annual Report summarizing the contents of the required records. Section 1002.7 requires that reports conform to reporting guides issued by CDRH unless an acceptable justification for an alternate format is provided

  5. 14 CFR 151.45 - Performance of construction work: General requirements.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 3 2010-01-01 2010-01-01 false Performance of construction work: General... § 151.45 Performance of construction work: General requirements. (a) All construction work under a... work under a project until— (1) The sponsor has furnished three conformed copies of the contract to the...

  6. 30 CFR 816.13 - Casing and sealing of drilled holes: General requirements.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 3 2010-07-01 2010-07-01 false Casing and sealing of drilled holes: General...-SURFACE MINING ACTIVITIES § 816.13 Casing and sealing of drilled holes: General requirements. Each exploration hole, other drill or borehole, well, or other exposed underground opening shall be cased, sealed...

  7. 40 CFR 267.198 - What are the general operating requirements for my tank systems?

    Science.gov (United States)

    2010-07-01

    ... FACILITIES OPERATING UNDER A STANDARDIZED PERMIT Tank Systems § 267.198 What are the general operating... 40 Protection of Environment 26 2010-07-01 2010-07-01 false What are the general operating requirements for my tank systems? 267.198 Section 267.198 Protection of Environment ENVIRONMENTAL PROTECTION...

  8. 20 CFR 604.3 - Able and available requirement-general principles.

    Science.gov (United States)

    2010-04-01

    ... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false Able and available requirement-general principles. 604.3 Section 604.3 Employees' Benefits EMPLOYMENT AND TRAINING ADMINISTRATION, DEPARTMENT OF...—general principles. (a) A State may pay UC only to an individual who is able to work and available for...

  9. 76 FR 36078 - Milk for Manufacturing Purposes and Its Production and Processing; Requirements Recommended for...

    Science.gov (United States)

    2011-06-21

    ...] Milk for Manufacturing Purposes and Its Production and Processing; Requirements Recommended for... to quality and sanitation requirements for the production and processing of manufacturing grade milk... Manufacturing Purposes and Its Production and Processing; Recommended Requirements for Adoption by State...

  10. 48 CFR 22.1503 - Procedures for acquiring end products on the List of Products Requiring Contractor Certification...

    Science.gov (United States)

    2010-10-01

    ... end products on the List of Products Requiring Contractor Certification as to Forced or Indentured... products on the List of Products Requiring Contractor Certification as to Forced or Indentured Child Labor... contracting officer must check the List of Products Requiring Contractor Certification as to Forced or...

  11. Teaching Management Information Systems as a General Education Requirement (GER) Capstone

    Science.gov (United States)

    Hoanca, Bogdan

    2012-01-01

    Although many IS programs nationwide use capstone courses in the major, this paper reports on the use of an upper division Management Information Systems (MIS) class as a general education requirements (GER) capstone. The class is a core requirement for all majors in the Bachelor of Business Administration (BBA) program at the University of Alaska…

  12. General requirements to implement the personal dose equivalent Hp(10) in Brazil

    International Nuclear Information System (INIS)

    Lopes, Amanda Gomes; Silva, Francisco Cesar Augusto da

    2017-01-01

    To update the dosimetry quantity with the international community, Brazil is changing the Individual Dose Hx to the Personal Dose Equivalent Hp(10). A bibliographical survey on the technical and administrative requirements of nine countries that use Hp(10) was carried out to obtain the most relevant ones. All of them follow IEC and ISO guidelines for technical requirements, while administrative requirements change from country to country. Based on countries experiences, this paper presents a list of important general requirements to implement Hp(10) and to prepare the Brazilian requirements according to the international scientific community. (author)

  13. General requirements to implement the personal dose equivalent Hp(10) in Brazil

    Energy Technology Data Exchange (ETDEWEB)

    Lopes, Amanda Gomes; Silva, Francisco Cesar Augusto da, E-mail: amandagl@bolsista.ird.gov.br [Instituto de Radioproteção e Dosimetria (IRD/CNEN-RJ), Rio de Janeiro, RJ (Brazil)

    2017-07-01

    To update the dosimetry quantity with the international community, Brazil is changing the Individual Dose Hx to the Personal Dose Equivalent Hp(10). A bibliographical survey on the technical and administrative requirements of nine countries that use Hp(10) was carried out to obtain the most relevant ones. All of them follow IEC and ISO guidelines for technical requirements, while administrative requirements change from country to country. Based on countries experiences, this paper presents a list of important general requirements to implement Hp(10) and to prepare the Brazilian requirements according to the international scientific community. (author)

  14. A general product measurability theorem with applications to variational inequalities

    Directory of Open Access Journals (Sweden)

    Kenneth L. Kuttler

    2016-03-01

    Full Text Available This work establishes the existence of measurable weak solutions to evolution problems with randomness by proving and applying a novel theorem on product measurability of limits of sequences of functions. The measurability theorem is used to show that many important existence theorems within the abstract theory of evolution inclusions or equations have straightforward generalizations to settings that include random processes or coefficients. Moreover, the convex set where the solutions are sought is not fixed but may depend on the random variables. The importance of adding randomness lies in the fact that real world processes invariably involve randomness and variability. Thus, this work expands substantially the range of applications of models with variational inequalities and differential set-inclusions.

  15. Moly99 Production Facility: Report on Beamline Components, Requirements, Costs

    Energy Technology Data Exchange (ETDEWEB)

    Bishofberger, Kip A. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2015-12-23

    In FY14 we completed the design of the beam line for the linear accelerator production design concept. This design included a set of three bending magnets, quadrupole focusing magnets, and octopoles to flatten the beam on target. This design was generic and applicable to multiple different accelerators if necessary. In FY15 we built on that work to create specifications for the individual beam optic elements, including power supply requirements. This report captures the specification of beam line components with initial cost estimates for the NorthStar production facility.This report is organized as follows: The motivation of the beamline design is introduced briefly, along with renderings of the design. After that, a specific list is provided, which accounts for each beamline component, including part numbers and costs, to construct the beamline. After that, this report details the important sections of the beamline and individual components. A final summary and list of follow-on activities completes this report.

  16. [Storage of plant protection products in farms: minimum safety requirements].

    Science.gov (United States)

    Dutto, Moreno; Alfonzo, Santo; Rubbiani, Maristella

    2012-01-01

    Failure to comply with requirements for proper storage and use of pesticides in farms can be extremely hazardous and the risk of accidents involving farm workers, other persons and even animals is high. There are still wide differences in the interpretation of the concept of "securing or making safe", by workers in this sector. One of the critical points detected, particularly in the fruit sector, is the establishment of an adequate storage site for plant protection products. The definition of "safe storage of pesticides" is still unclear despite the recent enactment of Legislative Decree 81/2008 regulating health and work safety in Italy. In addition, there are no national guidelines setting clear minimum criteria for storage of plant protection products in farms. The authors, on the basis of their professional experience and through analysis of recent legislation, establish certain minimum safety standards for storage of pesticides in farms.

  17. Forecast of wind energy production and ensuring required balancing power

    International Nuclear Information System (INIS)

    Merkulov, M.

    2010-01-01

    The wind energy is gaining larger part of the energy mix around the world as well as in Bulgaria. Having in mind the irregularity of the wind, we are in front of a challenge for management of the power grid in new unknown conditions. The world's experience has proven that there could be no effective management of the grid without forecasting tools, even with small scale of wind power penetration. Application of such tools promotes simple management of large wind energy production and reduction of the quantities of required balancing powers. The share of the expenses and efforts for forecasting of the wind energy is incomparably small in comparison with expenses for keeping additional powers in readiness. The recent computers potential allow simple and rapid processing of large quantities of data from different sources, which provides required conditions for modeling the world's climate and producing sophisticated forecast. (author)

  18. General Fund Enterprise Business System Did Not Provide Required Financial Information

    Science.gov (United States)

    2012-03-26

    Management of the General Fund Enterprise Business System,” January 14, 2008 Army AAA Report No. A-2010-0187- FFM , “General Fund Enterprise Business System...A-2009-0232- FFM , “General Fund Enterprise Business System – Federal Financial Management Improvement Act Compliance, Examination of Releases...1.4.1, 1.4.2, 1.4.3, and 1.4.4 Requirements,” September 30, 2009 AAA Report No. A-2009-0231- FFM , “General Fund Enterprise Business System – Federal

  19. The Identification and Comparison of the Requirements Placed on Product Managers during the Recruitment Process

    Directory of Open Access Journals (Sweden)

    Wroblowská Zuzana

    2015-09-01

    Full Text Available The submitted paper focuses on personality traits and behavioural competencies of a key role bearer in product oriented marketing management, generally referred to as product management. An interdisciplinary approach was applied while looking into this subject, since both research into theoretical bases and analysis of the current state of the topic and the tendencies of its development required work in several fields of study. Based on research in the field of secondary data, the assumption was set that a product manager is an example of a knowledge worker of the 21st century and that the business practice sees him/her as such, which has an effect on the requirements a candidate for this position is confronted with in the recruitment process. An independent research project was carried out and it confirmed that product managers are considered to be knowledge workers and that independence and analytical thinking skills were among the most common requirements for product managers both in 2007 and 2014. A comparison of results from 2007 and 2014 also showed some differences. The statistical verification confirmed a shift in requirements within the interpersonal competency group. The findings were used to formulate recommendations for the recruitment strategy and realization of selection for positions in product management.

  20. European Utility Requirements (EUR) - the organisation and its products

    International Nuclear Information System (INIS)

    Ingemarsson, K.F.

    2007-01-01

    The idea of a common specification for the development and construction of new nuclear power plants appeared in Usa in the eighties in the framework of the ALWR program (Advanced Light Water Reactors). Several European electricity producers had participated in the writing of the EPRI -Utility Requirement Document (URD)- together with a group of American and Asian companies, but in the early nineties, they also agreed to produce a European document. The point was to write a more open specification (open to non-US designs) that would take into account specific European requirements, in nuclear safety in particular, while still keeping strong references to the EPRI URD. In late 1991, five of the major European electricity producers set up an organisation to develop the EUR document. Their primary objective was to produce a common set of requirements that could be endorsed by the major European electricity producers and that would provide clear guidance to the designers. The EUR document (EUR stands for European Utility Requirements) was born. Building new nuclear plants would require undisputable competitiveness vs. alternate production sources. For that only standardisation could bring an adequate answer in the coming years. Standardisation of the designs call for harmonization of the design rules, especially the ones related to nuclear safety. The EUR utilities support the initiatives that would pave the way to harmonization of the safety design rules at European level. They nevertheless think that it may be needed to go further and eventually consider an overall re-optimisation of the safety design rules. All these developments shall be organised at European level, keeping strong connections with the other methodological works undertaken outside Europe. The European utilities and the vendors have now an updated and well-tuned tool that allows them to develop, to assess and to order modern LWR designs well fitted to their actual needs. It has been used as the base

  1. 9 CFR 590.410 - Shell eggs and egg products required to be labeled.

    Science.gov (United States)

    2010-01-01

    ... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false Shell eggs and egg products required..., DEPARTMENT OF AGRICULTURE EGG PRODUCTS INSPECTION INSPECTION OF EGGS AND EGG PRODUCTS (EGG PRODUCTS INSPECTION ACT) Identifying and Marking Product § 590.410 Shell eggs and egg products required to be labeled...

  2. PML tumor suppressor protein is required for HCV production

    International Nuclear Information System (INIS)

    Kuroki, Misao; Ariumi, Yasuo; Hijikata, Makoto; Ikeda, Masanori; Dansako, Hiromichi; Wakita, Takaji; Shimotohno, Kunitada; Kato, Nobuyuki

    2013-01-01

    Highlights: ► PML tumor suppressor protein is required for HCV production. ► PML is dispensable for HCV RNA replication. ► HCV could not alter formation of PML-NBs. ► INI1 and DDX5, PML-related proteins, are involved in HCV life cycle. -- Abstract: PML tumor suppressor protein, which forms discrete nuclear structures termed PML-nuclear bodies, has been associated with several cellular functions, including cell proliferation, apoptosis and antiviral defense. Recently, it was reported that the HCV core protein colocalizes with PML in PML-NBs and abrogates the PML function through interaction with PML. However, role(s) of PML in HCV life cycle is unknown. To test whether or not PML affects HCV life cycle, we examined the level of secreted HCV core and the infectivity of HCV in the culture supernatants as well as the level of HCV RNA in HuH-7-derived RSc cells, in which HCV-JFH1 can infect and efficiently replicate, stably expressing short hairpin RNA targeted to PML. In this context, the level of secreted HCV core and the infectivity in the supernatants from PML knockdown cells was remarkably reduced, whereas the level of HCV RNA in the PML knockdown cells was not significantly affected in spite of very effective knockdown of PML. In fact, we showed that PML is unrelated to HCV RNA replication using the subgenomic HCV-JFH1 replicon RNA, JRN/3-5B. Furthermore, the infectivity of HCV-like particle in the culture supernatants was significantly reduced in PML knockdown JRN/3-5B cells expressing core to NS2 coding region of HCV-JFH1 genome using the trans-packaging system. Finally, we also demonstrated that INI1 and DDX5, the PML-related proteins, are involved in HCV production. Taken together, these findings suggest that PML is required for HCV production.

  3. TYPES OF BANAT RURAL TOURIST PRODUCTS REQUIRED BY INTERNATIONAL TOURISTS

    Directory of Open Access Journals (Sweden)

    Cornelia Petroman

    2016-11-01

    Full Text Available Touristproducts express the training way and content of tourism offer, being a sum ofmaterial goods and services designed to meet the requirements and motivationsof tourists. Tourist services are individualized through a lot ofcharacteristics: elasticity of consumption, the material or immaterialexistence, the impossibility of storing, the simultaneity of consumption withthe production one, the impossibility of avoiding some differences. Thestructure of Banat tourist products focuses on several essential componentsbecause of the multiculturalism of this area, but also specific entrophic andnatural resources, natural reservations, historic sites, great diversity offlora and fauna due temperate or sub-Mediterranean climate subtypes. Economicactivities as support of agricultural occupations have trends of orientationtowards the tertiary sector stimulating the growth of niche tourism, ofmultiethnic space and multi confessional, being the supporting element oftourist services offered and through and through multilingualism increase theidentity of culture and civilization. The economic rural activities, populationand territory offers to Banat rural tourist product a note of originality,authenticity and attractiveness, the novelty of Banat village consisting frommanufacturing activities, habits and popular, the traditions archaicmulinologic installations and technical oil extraction, gastronomy, naturalmonuments, monastic religious services, diversity of hilly and steppe landscape.

  4. Requirement of argininosuccinate lyase for systemic nitric oxide production.

    Science.gov (United States)

    Erez, Ayelet; Nagamani, Sandesh C S; Shchelochkov, Oleg A; Premkumar, Muralidhar H; Campeau, Philippe M; Chen, Yuqing; Garg, Harsha K; Li, Li; Mian, Asad; Bertin, Terry K; Black, Jennifer O; Zeng, Heng; Tang, Yaoping; Reddy, Anilkumar K; Summar, Marshall; O'Brien, William E; Harrison, David G; Mitch, William E; Marini, Juan C; Aschner, Judy L; Bryan, Nathan S; Lee, Brendan

    2011-11-13

    Nitric oxide (NO) is crucial in diverse physiological and pathological processes. We show that a hypomorphic mouse model of argininosuccinate lyase (encoded by Asl) deficiency has a distinct phenotype of multiorgan dysfunction and NO deficiency. Loss of Asl in both humans and mice leads to reduced NO synthesis, owing to both decreased endogenous arginine synthesis and an impaired ability to use extracellular arginine for NO production. Administration of nitrite, which can be converted into NO in vivo, rescued the manifestations of NO deficiency in hypomorphic Asl mice, and a nitric oxide synthase (NOS)-independent NO donor restored NO-dependent vascular reactivity in humans with ASL deficiency. Mechanistic studies showed that ASL has a structural function in addition to its catalytic activity, by which it contributes to the formation of a multiprotein complex required for NO production. Our data demonstrate a previously unappreciated role for ASL in NOS function and NO homeostasis. Hence, ASL may serve as a target for manipulating NO production in experimental models, as well as for the treatment of NO-related diseases.

  5. 48 CFR 622.1503 - Procedures for acquiring end products on the List of Products Requiring Contractor Certification...

    Science.gov (United States)

    2010-10-01

    ... end products on the List of Products Requiring Contractor Certification as to Forced or Indentured... List of Products Requiring Contractor Certification as to Forced or Indentured Child Labor. (e) The... manufacture an end product furnished pursuant to a contract awarded subject to the certification required in...

  6. 75 FR 61418 - Milk for Manufacturing Purposes and Its Production and Processing; Requirements Recommended for...

    Science.gov (United States)

    2010-10-05

    ... for Manufacturing Purposes and Its Production and Processing; Requirements Recommended for Adoption by... sanitation requirements for the production and processing of manufacturing grade milk. These Recommended... comments. SUMMARY: This document proposes to amend the recommended manufacturing milk requirements...

  7. 75 FR 22540 - Review of Arbitration Awards; Miscellaneous and General Requirements

    Science.gov (United States)

    2010-04-29

    ... the Authority's existing practice for calculating the date for filing timely exceptions, so that the... general rules regarding calculating filing periods; and Sec. 2429.22 to specify that the rules set forth..., investment, productivity, innovation, or on the ability of United States-based companies to compete with...

  8. 9 CFR 590.24 - Egg products plants requiring continuous inspection.

    Science.gov (United States)

    2010-01-01

    ... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false Egg products plants requiring..., DEPARTMENT OF AGRICULTURE EGG PRODUCTS INSPECTION INSPECTION OF EGGS AND EGG PRODUCTS (EGG PRODUCTS INSPECTION ACT) Scope of Inspection § 590.24 Egg products plants requiring continuous inspection. No plant in...

  9. 78 FR 72033 - Approval and Promulgation of Implementation Plans; Florida: General Requirements and Gasoline...

    Science.gov (United States)

    2013-12-02

    ...] Approval and Promulgation of Implementation Plans; Florida: General Requirements and Gasoline Vapor Control... Protection (FDEP), related to the State's gasoline vapor recovery program. This correcting amendment corrects... . SUPPLEMENTARY INFORMATION: This action corrects inadvertent errors in a rulemaking related to Florida's gasoline...

  10. Interdisciplinary Science Courses for College General Education Requirements: Perspectives of Faculty at a State University.

    Science.gov (United States)

    Dass, Pradeep Maxwell

    Science educators have been advocating a broader role for science education--that of helping all students see the relevance of science to their own lives. Yet the only experience with post-secondary science that non-science majors get is through a couple of science courses which are part of the general education requirements (GERs) for a liberal…

  11. General requirements for concrete containment structures for CANDU nuclear power plants

    International Nuclear Information System (INIS)

    1993-07-01

    This standard provides the general requirements used in the design, construction, testing, and commissioning of concrete containment structures for CANDU nuclear power plants designated as class containment and is directed to the owners, designers, manufacturers, fabricators, and constructors of the concrete components and parts

  12. 77 FR 54499 - Microorganisms; General Exemptions From Reporting Requirements; Revisions to Recipient Organisms...

    Science.gov (United States)

    2012-09-05

    ... within 1 month. Survival was longer for a genetically modified B. amyloliquefaciens strain on leaf... Microorganisms; General Exemptions From Reporting Requirements; Revisions to Recipient Organisms Eligible for... manufacturer must use one of the recipient organisms listed in Sec. 725.420, and must implement specific...

  13. 29 CFR 4.172 - Meeting requirements for particular fringe benefits-in general.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 1 2010-07-01 2010-07-01 true Meeting requirements for particular fringe benefits-in... particular fringe benefits—in general. Where a fringe benefit determination specifies the amount of the..., as such costs are properly a business expense of the employer. If prevailing fringe benefits for...

  14. 26 CFR 1.25A-1 - Calculation of education tax credit and general eligibility requirements.

    Science.gov (United States)

    2010-04-01

    ... Scholarship Credit is claimed may not be taken into account in computing the amount of the Lifetime Learning... tax credit and general eligibility requirements. (a) Amount of education tax credit. An individual... Scholarship Credit (as described in § 1.25A-3) plus the Lifetime Learning Credit (as described in § 1.25A-4...

  15. 34 CFR 350.10 - What are the general requirements for Disability and Rehabilitation Research Projects?

    Science.gov (United States)

    2010-07-01

    ... more of the following types of activities, as specified in §§ 350.13-350.19: (1) Research. (2... 34 Education 2 2010-07-01 2010-07-01 false What are the general requirements for Disability and Rehabilitation Research Projects? 350.10 Section 350.10 Education Regulations of the Offices of the Department of...

  16. 42 CFR 84.99 - Man tests; testing conditions; general requirements.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Man tests; testing conditions; general requirements. 84.99 Section 84.99 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES OCCUPATIONAL SAFETY AND HEALTH RESEARCH AND RELATED ACTIVITIES APPROVAL OF RESPIRATORY PROTECTIVE DEVICES Self-Contained Breathing Apparatus § 84.99...

  17. 40 CFR 1033.201 - General requirements for obtaining a certificate of conformity.

    Science.gov (United States)

    2010-07-01

    ... certificate of conformity. 1033.201 Section 1033.201 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY....201 General requirements for obtaining a certificate of conformity. Certification is the process by... certificate of conformity for freshly manufactured locomotives. Anyone meeting the definition of...

  18. PML tumor suppressor protein is required for HCV production

    Energy Technology Data Exchange (ETDEWEB)

    Kuroki, Misao [Department of Tumor Virology, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, 2-5-1, Shikata-cho, Okayama 700-8558 (Japan); Research Fellow of the Japan Society for the Promotion of Science (Japan); Center for AIDS Research, Kumamoto University, Kumamoto 860-0811 (Japan); Ariumi, Yasuo, E-mail: ariumi@kumamoto-u.ac.jp [Department of Tumor Virology, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, 2-5-1, Shikata-cho, Okayama 700-8558 (Japan); Center for AIDS Research, Kumamoto University, Kumamoto 860-0811 (Japan); Hijikata, Makoto [Department of Viral Oncology, Institute for Virus Research, Kyoto University, Kyoto 606-8507 (Japan); Ikeda, Masanori; Dansako, Hiromichi [Department of Tumor Virology, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, 2-5-1, Shikata-cho, Okayama 700-8558 (Japan); Wakita, Takaji [Department of Virology II, National Institute of Infectious Diseases, Tokyo 162-8640 (Japan); Shimotohno, Kunitada [Research Center for Hepatitis and Immunology, National Center for Global Health and Medicine, Ichikawa, Chiba 272-8516 (Japan); Kato, Nobuyuki [Department of Tumor Virology, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, 2-5-1, Shikata-cho, Okayama 700-8558 (Japan)

    2013-01-11

    Highlights: Black-Right-Pointing-Pointer PML tumor suppressor protein is required for HCV production. Black-Right-Pointing-Pointer PML is dispensable for HCV RNA replication. Black-Right-Pointing-Pointer HCV could not alter formation of PML-NBs. Black-Right-Pointing-Pointer INI1 and DDX5, PML-related proteins, are involved in HCV life cycle. -- Abstract: PML tumor suppressor protein, which forms discrete nuclear structures termed PML-nuclear bodies, has been associated with several cellular functions, including cell proliferation, apoptosis and antiviral defense. Recently, it was reported that the HCV core protein colocalizes with PML in PML-NBs and abrogates the PML function through interaction with PML. However, role(s) of PML in HCV life cycle is unknown. To test whether or not PML affects HCV life cycle, we examined the level of secreted HCV core and the infectivity of HCV in the culture supernatants as well as the level of HCV RNA in HuH-7-derived RSc cells, in which HCV-JFH1 can infect and efficiently replicate, stably expressing short hairpin RNA targeted to PML. In this context, the level of secreted HCV core and the infectivity in the supernatants from PML knockdown cells was remarkably reduced, whereas the level of HCV RNA in the PML knockdown cells was not significantly affected in spite of very effective knockdown of PML. In fact, we showed that PML is unrelated to HCV RNA replication using the subgenomic HCV-JFH1 replicon RNA, JRN/3-5B. Furthermore, the infectivity of HCV-like particle in the culture supernatants was significantly reduced in PML knockdown JRN/3-5B cells expressing core to NS2 coding region of HCV-JFH1 genome using the trans-packaging system. Finally, we also demonstrated that INI1 and DDX5, the PML-related proteins, are involved in HCV production. Taken together, these findings suggest that PML is required for HCV production.

  19. Thermodynamic Product Relations for Generalized Regular Black Hole

    International Nuclear Information System (INIS)

    Pradhan, Parthapratim

    2016-01-01

    We derive thermodynamic product relations for four-parametric regular black hole (BH) solutions of the Einstein equations coupled with a nonlinear electrodynamics source. The four parameters can be described by the mass (m), charge (q), dipole moment (α), and quadrupole moment (β), respectively. We study its complete thermodynamics. We compute different thermodynamic products, that is, area product, BH temperature product, specific heat product, and Komar energy product, respectively. Furthermore, we show some complicated function of horizon areas that is indeed mass-independent and could turn out to be universal.

  20. General description and production lines of the Egyptian fuel manufacturing pilot plant

    International Nuclear Information System (INIS)

    Zidan, W.I.; Elseaidy, I.M.

    1999-01-01

    The Egyptian Fuel Manufacturing Pilot Plant, FMPP, is a new facility, producing an MTR-type fuel elements required for the Egyptian Second Research Reactor, ETRR-2, as well as other plates or elements for an external clients with the same type and enrichment percent or lower, (LEU). General description is presented. The production lines in FMPP, which begin from uranium hexaflouride (UF 6 , 19.7±0.2 % U 235 by wt), aluminum powder, and nuclear grade 6061 aluminium alloy in sheets, bars, and rods with the different heat treatments and dimensions as a raw materials, are processed through a series of the manufacturing, inspection, and quality control plan to produce the final specified MTR-type fuel elements. All these processes and the product control in each step are presented. The specifications of the final product are presented. (author)

  1. Generalized Information Architecture for Managing Requirements in IBM?s Rational DOORS(r) Application.

    Energy Technology Data Exchange (ETDEWEB)

    Aragon, Kathryn M.; Eaton, Shelley M.; McCornack, Marjorie Turner; Shannon, Sharon A.

    2014-12-01

    When a requirements engineering effort fails to meet expectations, often times the requirements management tool is blamed. Working with numerous project teams at Sandia National Laboratories over the last fifteen years has shown us that the tool is rarely the culprit; usually it is the lack of a viable information architecture with well- designed processes to support requirements engineering. This document illustrates design concepts with rationale, as well as a proven information architecture to structure and manage information in support of requirements engineering activities for any size or type of project. This generalized information architecture is specific to IBM's Rational DOORS (Dynamic Object Oriented Requirements System) software application, which is the requirements management tool in Sandia's CEE (Common Engineering Environment). This generalized information architecture can be used as presented or as a foundation for designing a tailored information architecture for project-specific needs. It may also be tailored for another software tool. Version 1.0 4 November 201

  2. PVD and gas production: consider local resource access requirements

    International Nuclear Information System (INIS)

    Delafosse, E.

    1993-01-01

    The history of the natural gas industry worldwide teaches us that its development has sprung mainly from two sources: favorable contingent conditions, such as in the United States, where the discovery of large gas fields coincided favorably with technological progress and the already existing city gas distribution networks, as also happened in Italy and France; and political prodding, as in the Eastern European countries, in Japan, and certain countries of Western Europe too. Today, while natural gas is winning over more and more consumers and the infrastructures now exist, the rise in consumption is being held back by supply-related constraints, and namely the problem of adjusting to the rise in gas prices in the United States, and the distancing of the resources from Europe. In this context, the development of new gas markets in the developing countries could contribute to the continuous growth of the world natural gas industry. The resources do exist, and the possibility of generating electricity with them opens the way to creating or developing this industry in some twenty developing countries, to begin with, and a greater number later. For these countries, this perspective is highly enticing, economically; but development is slow, partly due to the fact that the specific requirements of gas production projects are not satisfied. The contractual and tax structure governing their implementation does not reflect the fact that, in contrast to the petroleum industry, the producer does not have access to a true market, and he is in fact only one of the wheels in an integrated production mechanism bent specifically on putting electrical power on the market. It is easy to see the difficulties that arise from such a situation, since the indispensable steps in the process, performed successively by producer, transporter, and electric company, use two interfaces with fields of business that are in close bilateral dependency. This leads to upstream inefficiency in

  3. Tributyltin-induced apoptosis requires glycolytic adenosine trisphosphate production.

    Science.gov (United States)

    Stridh, H; Fava, E; Single, B; Nicotera, P; Orrenius, S; Leist, M

    1999-10-01

    The toxicity of tributyltin chloride (TBT) involves Ca(2+) overload, cytoskeletal damage, and mitochondrial failure leading to cell death by apoptosis or necrosis. Here, we examined whether the intracellular ATP level modulates the mode of cell death after exposure to TBT. When Jurkat cells were energized by the mitochondrial substrate, pyruvate, low concentrations of TBT (1-2 microM) triggered an immediate depletion of intracellular ATP followed by necrotic death. When ATP levels were maintained by the addition of glucose, the mode of cell death was typically apoptotic. Glycolytic ATP production was required for apoptosis at two distinct steps. First, maintenance of adequate ATP levels accelerated the decrease of mitochondrial membrane potential, and the release of the intermembrane proteins adenylate kinase and cytochrome c from mitochondria. A possible role of the adenine nucleotide exchanger in this first ATP-dependent step is suggested by experiments performed with the specific inhibitor, bongkrekic acid. This substance delayed cytochrome c release in a manner similar to that caused by ATP depletion. Second, caspase activation following cytochrome c release was only observed in ATP-containing cells. Bcl-2 had only a minor effect on TBT-triggered caspase activation or cell death. We conclude that intracellular ATP concentrations control the mode of cell death in TBT-treated Jurkat cells at both the mitochondrial and caspase activation levels.

  4. FDA's requirements for radiation dosimetry of radiopharmaceutical drug products

    International Nuclear Information System (INIS)

    Abel, N.M.

    1986-01-01

    The primary concern of the Office of Drug Research and Review of the Food and Drug Administration in the field of radiation dosimetry is to ensure that radiopharmaceutical drug products are safe when used as investigational drugs (INDs) and are both safe and effective when a new drug application (NDA) is approved. In order to accomplish this, the sponsor of either an IND or applicant in the case of NDA must provide information that clearly describes the radiation dose that a patient will receive from the administration of the drug. The submitted numerical estimates of the radiation dose should be based on an absorbed fraction method of radiation dose calculation, such as the system set forth by the Medical Internal Radiation Dose (MIRD) Committee of the Society of Nuclear Medicine or the system set forth by the International Commission on Radiological Protection (ICRP). This presentation will describe in detail the data that a sponsor of an IND needs to submit to satisfy the regulatory requirements. Examples will be given of common mistakes and omissions by sponsors in their presentation of data

  5. Reduction in requirements for allogeneic blood products: nonpharmacologic methods.

    Science.gov (United States)

    Hardy, J F; Bélisle, S; Janvier, G; Samama, M

    1996-12-01

    Various strategies have been proposed to decrease bleeding and allogeneic transfusion requirements during and after cardiac operations. This article attempts to document the usefulness, or lack thereof, of the nonpharmacologic methods available in clinical practice. Blood conservation methods were reviewed in chronologic order, as they become available to patients during the perisurgical period. The literature in support of or against each strategy was reexamined critically. Avoidance of preoperative anemia and adherence to published guidelines for the practice of transfusion are of paramount importance. Intraoperatively, tolerance of low hemoglobin concentrations and use of autologous blood (predonated or harvested before bypass) will reduce allogeneic transfusions. The usefulness of plateletpheresis and retransfusion of shed mediastinal fluid remains controversial. Intraoperatively and postoperatively, maintenance of normothermia contributes to improved hemostasis. Several approaches have been shown to be effective. An efficient combination of methods can reduce, and sometimes abolish, the need for allogeneic blood products after cardiac operations, inasmuch as all those involved in the care of cardiac surgical patients adhere thoughtfully to existing transfusion guidelines.

  6. Safety Assessment for Facilities and Activities. General Safety Requirements. Pt. 4

    International Nuclear Information System (INIS)

    2009-01-01

    The Safety Fundamentals publication, Fundamental Safety Principles, establishes principles for ensuring the protection of workers, the public and the environment, now and in the future, from harmful effects of ionizing radiation. The objective of this Safety Requirements publication is to establish the generally applicable requirements to be fulfilled in safety assessment for facilities and activities, with special attention paid to defence in depth, quantitative analyses and the application of a graded approach to the ranges of facilities and of activities that are addressed. The publication also addresses the independent verification of the safety assessment that needs to be carried out by the originators and users of the safety assessment. This publication is intended to provide a consistent and coherent basis for safety assessment across all facilities and activities, which will facilitate the transfer of good practices between organizations conducting safety assessments and will assist in enhancing the confidence of all interested parties that an adequate level of safety has been achieved for facilities and activities. The requirements, which are derived from the Fundamental Safety Principles, relate to any human activity that may cause people to be exposed to radiation risks arising from facilities and activities, as follows: Facilities includes: (a) Nuclear power plants; (b) Other reactors (such as research reactors and critical assemblies); (c) Enrichment facilities and fuel fabrication facilities; (d) Conversion facilities used to generate UF6; (e) Storage and reprocessing plants for irradiated fuel; (f) Facilities for radioactive waste management where radioactive waste is treated, conditioned, stored or disposed of; (g) Any other places where radioactive materials are produced, processed, used, handled or stored; (h) Irradiation facilities for medical, industrial, research and other purposes, and any places where radiation generators are installed; (i

  7. Safety assessment for facilities and activities. General safety requirements. Pt. 4

    International Nuclear Information System (INIS)

    2009-01-01

    The Safety Fundamentals publication, Fundamental Safety Principles, establishes principles for ensuring the protection of workers, the public and the environment, now and in the future, from harmful effects of ionizing radiation. The objective of this Safety Requirements publication is to establish the generally applicable requirements to be fulfilled in safety assessment for facilities and activities, with special attention paid to defence in depth, quantitative analyses and the application of a graded approach to the ranges of facilities and of activities that are addressed. The publication also addresses the independent verification of the safety assessment that needs to be carried out by the originators and users of the safety assessment. This publication is intended to provide a consistent and coherent basis for safety assessment across all facilities and activities, which will facilitate the transfer of good practices between organizations conducting safety assessments and will assist in enhancing the confidence of all interested parties that an adequate level of safety has been achieved for facilities and activities. The requirements, which are derived from the Fundamental Safety Principles, relate to any human activity that may cause people to be exposed to radiation risks arising from facilities and activities, as follows: Facilities includes: (a) Nuclear power plants; (b) Other reactors (such as research reactors and critical assemblies); (c) Enrichment facilities and fuel fabrication facilities; (d) Conversion facilities used to generate UF 6 ; (e) Storage and reprocessing plants for irradiated fuel; (f) Facilities for radioactive waste management where radioactive waste is treated, conditioned, stored or disposed of; (g) Any other places where radioactive materials are produced, processed, used, handled or stored; (h) Irradiation facilities for medical, industrial, research and other purposes, and any places where radiation generators are installed; (i

  8. Safety Assessment for Facilities and Activities. General Safety Requirements. Pt. 4

    International Nuclear Information System (INIS)

    2010-01-01

    The Safety Fundamentals publication, Fundamental Safety Principles, establishes principles for ensuring the protection of workers, the public and the environment, now and in the future, from harmful effects of ionizing radiation. The objective of this Safety Requirements publication is to establish the generally applicable requirements to be fulfilled in safety assessment for facilities and activities, with special attention paid to defence in depth, quantitative analyses and the application of a graded approach to the ranges of facilities and of activities that are addressed. The publication also addresses the independent verification of the safety assessment that needs to be carried out by the originators and users of the safety assessment. This publication is intended to provide a consistent and coherent basis for safety assessment across all facilities and activities, which will facilitate the transfer of good practices between organizations conducting safety assessments and will assist in enhancing the confidence of all interested parties that an adequate level of safety has been achieved for facilities and activities. The requirements, which are derived from the Fundamental Safety Principles, relate to any human activity that may cause people to be exposed to radiation risks arising from facilities and activities, as follows: Facilities includes: (a) Nuclear power plants; (b) Other reactors (such as research reactors and critical assemblies); (c) Enrichment facilities and fuel fabrication facilities; (d) Conversion facilities used to generate UF6; (e) Storage and reprocessing plants for irradiated fuel; (f) Facilities for radioactive waste management where radioactive waste is treated, conditioned, stored or disposed of; (g) Any other places where radioactive materials are produced, processed, used, handled or stored; (h) Irradiation facilities for medical, industrial, research and other purposes, and any places where radiation generators are installed; (i

  9. Safety Assessment for Facilities and Activities. General Safety Requirements. Pt. 4

    International Nuclear Information System (INIS)

    2009-01-01

    The Safety Fundamentals publication, Fundamental Safety Principles, establishes principles for ensuring the protection of workers, the public and the environment, now and in the future, from harmful effects of ionizing radiation.? read more The objective of this Safety Requirements publication is to establish the generally applicable requirements to be fulfilled in safety assessment for facilities and activities, with special attention paid to defence in depth, quantitative analyses and the application of a graded approach to the ranges of facilities and of activities that are addressed. The publication also addresses the independent verification of the safety assessment that needs to be carried out by the originators and users of the safety assessment. This publication is intended to provide a consistent and coherent basis for safety assessment across all facilities and activities, which will facilitate the transfer of good practices between organizations conducting safety assessments and will assist in enhancing the confidence of all interested parties that an adequate level of safety has been achieved for facilities and activities. The requirements, which are derived from the Fundamental Safety Principles, relate to any human activity that may cause people to be exposed to radiation risks arising from facilities and activities, as follows: Facilities includes: (a) Nuclear power plants; (b) Other reactors (such as research reactors and critical assemblies); (c) Enrichment facilities and fuel fabrication facilities; (d) Conversion facilities used to generate UF6; (e) Storage and reprocessing plants for irradiated fuel; (f) Facilities for radioactive waste management where radioactive waste is treated, conditioned, stored or disposed of; (g) Any other places where radioactive materials are produced, processed, used, handled or stored; (h) Irradiation facilities for medical, industrial, research and other purposes, and any places where radiation generators are

  10. An integrated production-inventory model for food products adopting a general raw material procurement policy

    Science.gov (United States)

    Fauza, G.; Prasetyo, H.; Amanto, B. S.

    2018-05-01

    Studies on an integrated production-inventory model for deteriorating items have been done extensively. Most of the studies define deterioration as physical depletion of some inventories over time. This definition may not represent the deterioration characteristics of food products. The quality of food production decreases over time while the quantity remains the same. Further, in the existing models, the raw material is replenished several times (or at least once) within one production cycle. In food industries, however, a food company, for several reasons (e.g., the seasonal raw materials, discounted price, etc.) sometimes will get more benefit if it orders raw materials in a large quantity. Considering this fact, this research, therefore, is aimed at developing a more representative inventory model by (i) considering the quality losses in food and (ii) adopting a general raw material procurement policy. A mathematical model is established to represent the proposed policy in which the total profit of the system is the objective function. To evaluate the performance of the model, a numerical test was conducted. The numerical test indicates that the developed model has better performance, i.e., the total profit is 2.3% higher compared to the existing model.

  11. Development of CSA N1600-14: general requirements for nuclear emergency management programs

    Energy Technology Data Exchange (ETDEWEB)

    Sellar, C. [Canadian Standards Association Group, Mississauga, ON (Canada); Coles, J. [Ontario Power Generation, Darlington, ON (Canada)

    2014-07-01

    CSA Group has published a new standard on General requirements for nuclear emergency management programs (CSA N1600-14). The standard establishes criteria for the emergency management programs of on- and off-site organizations to address nuclear emergencies at Canadian nuclear power plants (NPPs). It provides the requirements to develop, implement, evaluate, maintain, and continuously improve a nuclear emergency management program for prevention and mitigation, preparedness, response, and recovery from a nuclear emergency at a NPP. This paper discusses the development of the standard, and provides the key drivers, structure, scope, and outline of the standard, while highlighting key features, impacts, and benefits. (author)

  12. Generalized requirements and decompositions for the design of test parts for micro additive manufacturing research

    DEFF Research Database (Denmark)

    Thompson, Mary Kathryn; Clemmensen, Line Katrine Harder

    2015-01-01

    The design of experimental test parts to characterize micro additive manufacturing (AM) processes is challenging due to the influence of the manufacturing and metrology processes. This work builds on the lessons learned from a case study in the literature to derive generalized requirements and high...... level decompositions for the design of test parts and the design of experiments to characterize micro additive manufacturing processes. While the test parts and the experiments described are still work in progress, the generic requirements derived from them can serve as a starting point for the design...... of other micro additive manufacturing related studies and their decompositions can help structure future work....

  13. The detailed balance requirement and general empirical formalisms for continuum absorption

    Science.gov (United States)

    Ma, Q.; Tipping, R. H.

    1994-01-01

    Two general empirical formalisms are presented for the spectral density which take into account the deviations from the Lorentz line shape in the wing regions of resonance lines. These formalisms satisfy the detailed balance requirement. Empirical line shape functions, which are essential to provide the continuum absorption at different temperatures in various frequency regions for atmospheric transmission codes, can be obtained by fitting to experimental data.

  14. Identifying the nontechnical skills required of nurses in general surgical wards.

    Science.gov (United States)

    Marshall, Dianne C; Finlayson, Mary P

    2018-04-01

    To identify the nontechnical skills (NTS) required of nurses in general surgical wards for safe and effective care. As the largest occupational group, nurses are in an ideal position to block the vulnerabilities of patient adverse events in a surgical ward. Previous studies in the surgical environment have identified the NTS required of nurses for safe care in operating rooms; however, these skills have not been identified for nurses in general surgical wards. A nonparticipant observational descriptive design was used. A purposive sample of 15 registered nurses was recruited from four surgical wards and observed for a full shift on a morning, afternoon or night shift. Nonparticipant observations were conducted using field notes to collect data. A coding frame was developed, and an inductive process was used to analyse the data. A taxonomy comprising seven NTS required of nurses in their roles in surgical ward teams emerged from the data analysis. They are communication, leadership and management, planning, decision-making, situation awareness, teamwork and patient advocacy. Patient care provided by general surgical nurses involved the seven identified key NTS. These particular NTS are an important component of safe nursing practice as they underpin the provision of safe and effective care for general surgical patients. Nurses block the trajectory of error by using NTS to address the vulnerabilities in the system that can lead to adverse patient events. Identifying general surgical nurses' NTS enables the development of teaching strategies that target the learning of those skills to achieve successful work outcomes and improve patient safety. © 2018 John Wiley & Sons Ltd.

  15. Structuring requirements as necessary premise for customer-oriented development of complex products: A generic approach

    Directory of Open Access Journals (Sweden)

    Sandra Klute

    2011-10-01

    Full Text Available Purpose: Complex products like for example intra-logistical facilities make high demands on developers and producers and involve high investment and operating costs. When planning and developing and also making buying decisions the facility utilization and the thus ensuing requirements on the facility and its components are inadequately considered to date. Nevertheless, with regard to customer-directed product design, these requirements must all be taken into account – especially as they can contribute to possible savings. In this context, it is necessary to survey and systematically regard requirements from a large number of areas like for example the operator, the facility producer and also requirements of external parties such as the law and to implement into adequate product characteristics to produce customer-oriented products. This is, however, a difficult task because of the diversity of stakeholders involved and their numerous and often divergent requirements. Therefore, it is essential to structure the requirements, so that planners and developers are able to manage the large amount of information. Structure models can be used in this context to cluster requirements. Within the German Collaborative Research Centre 696 a 10-dimensional model has been developed. This model allows structuring of all requirements on intra-logistical facilities or respectively complex products in general. In the context of dealing with hundreds of data records, structuring requirements is mandatory to achieve accuracy, clarity and consequently satisfactory results when transforming requirements into product characteristics which fit customer needs. In the paper an excerpt of this model is presented. Design/methodology/approach: In literature a multitude of methods which deal with the topic of structuring exist. The methods have been analysed regarding their purpose and their level of specification, i.e. the number of differentiated categories, to check if

  16. Performance requirements of an inertial-fusion-energy source for hydrogen production

    International Nuclear Information System (INIS)

    Hovingh, J.

    1983-01-01

    Performance of an inertial fusion system for the production of hydrogen is compared to a tandem-mirror-system hydrogen producer. Both systems use the General Atomic sulfur-iodine hydrogen-production cycle and produce no net electric power to the grid. An ICF-driven hydrogen producer will have higher system gains and lower electrical-consumption ratios than the design point for the tandem-mirror system if the inertial-fusion-energy gain eta Q > 8.8. For the ICF system to have a higher hydrogen production rate per unit fusion power than the tandem-mirror system requires that eta Q > 17. These can be achieved utilizing realistic laser and pellet performances

  17. 46 CFR 164.019-13 - Production quality control requirements.

    Science.gov (United States)

    2010-10-01

    ... establish procedures for maintaining quality control of the materials used in production, manufacturing... place of manufacture unless alternate procedures have been accepted by the Commandant. (c) Production... manufactured. A new lot must be started whenever any change is made in materials, design, or production method...

  18. Generic functional requirements for a NASA general-purpose data base management system

    Science.gov (United States)

    Lohman, G. M.

    1981-01-01

    Generic functional requirements for a general-purpose, multi-mission data base management system (DBMS) for application to remotely sensed scientific data bases are detailed. The motivation for utilizing DBMS technology in this environment is explained. The major requirements include: (1) a DBMS for scientific observational data; (2) a multi-mission capability; (3) user-friendly; (4) extensive and integrated information about data; (5) robust languages for defining data structures and formats; (6) scientific data types and structures; (7) flexible physical access mechanisms; (8) ways of representing spatial relationships; (9) a high level nonprocedural interactive query and data manipulation language; (10) data base maintenance utilities; (11) high rate input/output and large data volume storage; and adaptability to a distributed data base and/or data base machine configuration. Detailed functions are specified in a top-down hierarchic fashion. Implementation, performance, and support requirements are also given.

  19. General construction requirements for the deep repository in the KBS-3 system

    International Nuclear Information System (INIS)

    2002-10-01

    The KBS-3 systems includes equipment and plants for transport of spent nuclear fuels and encapsulated spent fuels, central intermediate storage, encapsulation and deep geologic disposal. The requirements in this document concern the repository and have been put together in view of the tasks of designing, constructing and building the repository. The report presents: A general review of existing design plans; Laws and regulations relevant for the design of the repository; How the regulations have been broken down to functional demands and dimensioning requirements for the repository; How the site conditions influence the design, and how the layout of the different parts of the repository interact; Relations between the functions of the repository, the safety and the design; A foundation for developing construction plans for the repository. The requirements will be collected in a database that will develop as new knowledge is collected

  20. [Contents of general flavonoides in Epimedium acuminatum Franch. and its differently-processed products].

    Science.gov (United States)

    Chen, H L; Wang, J K; Zhang, L L; Wu, Z Y

    2000-04-01

    Determining and comparing the contents of general flavonoides in four kinds of differently-processed products of Epimedium acuminatum. Determining the contents by ultraviolet spectrophotometry. The contents were found in the following seguence: unprocessed product, clearly-fried product, alcohol-broiled product, salt-broiled product, sheep-fat-broiled product. The average recovery rate was 96.01%, with a 0.74% RSD(n = 5). Heating causes the contents of general flavonoides in the processed products to decrease. These processed products are still often used in clinical treatment, for the reason that the adjuvant features certain coordinating and promoting functions. The study is to be pursued further.

  1. 10 CFR 503.8 - No alternate power supply-general requirement for certain exemptions for new powerplants.

    Science.gov (United States)

    2010-01-01

    ... 10 Energy 4 2010-01-01 2010-01-01 false No alternate power supply-general requirement for certain exemptions for new powerplants. 503.8 Section 503.8 Energy DEPARTMENT OF ENERGY (CONTINUED) ALTERNATE FUELS NEW FACILITIES General Requirements for Exemptions § 503.8 No alternate power supply—general...

  2. 77 FR 20051 - Notice of Final Determination Revising the List of Products Requiring Federal Contractor...

    Science.gov (United States)

    2012-04-03

    ... Products Requiring Federal Contractor Certification as to Forced or Indentured Child Labor Pursuant to... ``Procedural Guidelines for the Maintenance of the List of Products Requiring Federal Contractor Certification... List of Products Requiring Federal Contractor Certification as to Forced or Indentured Child Labor...

  3. General Approaches and Requirements on Safety and Security of Radioactive Materials Transport in Russian Federation

    International Nuclear Information System (INIS)

    Ershov, V.N.; Buchel'nikov, A.E.; Komarov, S.V.

    2016-01-01

    Development and implementation of safety and security requirements for transport of radioactive materials in the Russian Federation are addressed. At the outset it is worth noting that the transport safety requirements implemented are in full accordance with the IAEA's ''Regulations for the Safe Transport of Radioactive Material (2009 Edition)''. However, with respect to security requirements for radioactive material transport in some cases the Russian Federation requirements for nuclear material are more stringent compared to IAEA recommendations. The fundamental principles of safety and security of RM managements, recommended by IAEA documents (publications No. SF-1 and GOV/41/2001) are compared. Its correlation and differences concerning transport matters, the current level and the possibility of harmonization are analysed. In addition a reflection of the general approaches and concrete transport requirements is being evaluated. Problems of compliance assessment, including administrative and state control problems for safety and security provided at internal and international shipments are considered and compared. (author)

  4. It is generally appreciated that estuaries are productive systems that ...

    African Journals Online (AJOL)

    spamer

    Marine & Coastal Management, Private Bag X2, Rogge Bay 8012, South ... Percy FitzPatrick Institute, University of Cape Town, Rondebosch 7701, .... Va – Obligate catadromous species that require a freshwater phase in their development .... It is difficult to attribute the actual contribution of ... The 14 factors described in.

  5. 40 CFR 158.400 - Product performance data requirements table.

    Science.gov (United States)

    2010-07-01

    ... associated with human and animal wastes NR NR NR NR NR NR NR NR CR NR EP 1 91-8 Products for treating water... vertebrates (such as rodents, birds, bats, canids, and skunks) that may directly or indirectly transmit diseases to humans. However each registrant must ensure through testing that his product is efficacious...

  6. Are Skill Requirements Rising? Evidence from Production and Clerical Jobs.

    Science.gov (United States)

    Cappelli, Peter

    1993-01-01

    Examination of production jobs in 93 manufacturing firms (1978-86) and clerical jobs in 211 firms (1978-88) suggests (1) significant upskilling within most production jobs; (2) in clerical jobs, an even split between raised and lowered skill levels; and (3) decreasing skill levels associated with office automation. (SK)

  7. Water requirements for livestock production: a global perspective.

    Science.gov (United States)

    Schlink, A C; Nguyen, M L; Viljoen, G J

    2010-12-01

    Water is a vital but poorly studied component of livestock production. It is estimated that livestock industries consume 8% of the global water supply, with most of that water being used for intensive, feed-based production. This study takes a broad perspective of livestock production as a component of the human food chain, and considers the efficiency of its water use. Global models are in the early stages of development and do not distinguish between developing and developed countries, or the production systems within them. However, preliminary indications are that, when protein production is adjusted for biological value in the human diet, no plant protein is significantly more efficient at using water than protein produced from eggs, and only soybean is more water efficient than milk and goat and chicken meat. In some regions, especially developing countries, animals are not used solely for food production but also provide draught power, fibre and fertiliser for crops. In addition, animals make use of crop by-products that would otherwise go to waste. The livestock sector is the fastest-growing agricultural sector, which has led to increasing industrialisation and, in some cases, reduced environmental constraints. In emerging economies, increasing involvement in livestock is related to improving rural wealth and increasing consumption of animal protein. Water usage for livestock production should be considered an integral part of agricultural water resource management, taking into account the type of production system (e.g. grain-fed or mixed crop-livestock) and scale (intensive or extensive), the species and breeds of livestock, and the social and cultural aspects of livestock farming in various countries.

  8. 40 CFR 161.640 - Product performance data requirements.

    Science.gov (United States)

    2010-07-01

    ... or indirectly transmit diseases to humans. However, each registrant must ensure through testing that... microbial pests associated with human and animal wastes (1) CR EP* 91-7 Products for treating water systems...

  9. Guidelines for the Deployment of Product-Related Environmental Legislation into Requirements for the Product Development Process

    DEFF Research Database (Denmark)

    Ferraz, Mariana; Pigosso, Daniela Cristina Antelmi; Teixeira, Cláudia Echevenguá

    2013-01-01

    Environmental legislation is increasingly changing its focus from end-of-pipe approaches to a life cycle perspective. Therefore, manufacturing companies are increasingly identifying the need of deploying and incorporating product-related environmental requirements into the product development...... process. This paper presents twelve guidelines, clustered into three groups, to support companies in the identification, analysis and deployment of product requirements from product-related environmental legislation....

  10. 39 CFR 230.15 - What must an Office of Inspector General employee do if served with a demand requiring the...

    Science.gov (United States)

    2010-07-01

    ... 39 Postal Service 1 2010-07-01 2010-07-01 false What must an Office of Inspector General employee do if served with a demand requiring the production of documents or an appearance in court? 230.15 Section 230.15 Postal Service UNITED STATES POSTAL SERVICE ORGANIZATION AND ADMINISTRATION OFFICE OF...

  11. 75 FR 22746 - Third Party Testing for Certain Children's Products; Notice of Requirements for Accreditation of...

    Science.gov (United States)

    2010-04-30

    ... (ISO)/International Electrotechnical Commission (IEC) Standard 17025:2005, ``General Requirements for... and of the requirements of the ISO/IEC 17025:2005 laboratory accreditation standard is provided in the.../membersbycategory.html . The accreditation must be to ISO Standard ISO/IEC 17025:2005, ``General Requirements for...

  12. 75 FR 51016 - Third Party Testing for Certain Children's Products; Clothing Textiles: Requirements for...

    Science.gov (United States)

    2010-08-18

    ... (ISO)/International Electrotechnical Commission (IEC) Standard 17025:2005, ``General Requirements for... and of the requirements of the ISO/IEC 17025:2005 laboratory accreditation standard is provided in the... must be to ISO Standard ISO/IEC 17025:2005, ``General Requirements for the Competence of Testing and...

  13. 24 CFR 200.955 - Supplementary specific requirements under the HUD building product standard and certification...

    Science.gov (United States)

    2010-04-01

    ... under the HUD building product standard and certification program for fenestration products (windows and... Supplementary specific requirements under the HUD building product standard and certification program for... testing for a product shall be described in the specific building product certification program. In the...

  14. General characteristics of Bc-mesons. Production mechanisms and decays

    International Nuclear Information System (INIS)

    Gershtein, S.S.; Likhoded, A.K.; Slabospitsky, S.R.

    1989-01-01

    Using Martin potential, independent of b- and c-quark flavour, the mass spectrum of B c (bc-bar)-mesons and widths of electromagnetic transition between them are calculated. The estimations of the production cross section at e + e - colliders, in hadronic and neutrino interactions are obtained. A real possibility to observed B c mesons at LEP and also at hadron colliders (σ(B c )/σ(bb-bar)∼10 -3 ) has been pointed out. The importance of observing the annihilation decay channels of B c -mesons: B c →τν τ (Br(B c →τν τ )=1.5-2%), and B c →ΦD s , B C →DK etc, has been emphasized. 25 refs.; 16 figs.; 5 tabs

  15. Resolving Semantic Interference during Word Production Requires Central Attention

    Science.gov (United States)

    Kleinman, Daniel

    2013-01-01

    The semantic picture-word interference task has been used to diagnose how speakers resolve competition while selecting words for production. The attentional demands of this resolution process were assessed in 2 dual-task experiments (tone classification followed by picture naming). In Experiment 1, when pictures and distractor words were presented…

  16. 76 FR 737 - Tobacco Products, Exemptions From Substantial Equivalence Requirements

    Science.gov (United States)

    2011-01-06

    ... exemptions would be requested for an unknown number of the remaining products. Although in theory the maximum... place, only 50 exemption requests will be submitted per year. This may increase over time as learning..., and social science occupations ($30.91), architecture and engineering occupations ($40.93), and legal...

  17. 19 CFR 10.1 - Domestic products; requirements on entry.

    Science.gov (United States)

    2010-04-01

    ..., Harmonized Tariff Schedule of the United States (HTSUS): (1) A declaration by the foreign shipper in... and/or the reason for the exportation of the articles. (c) A certificate from the master of a vessel... or production of other evidence, that the articles are imported in circumstances meeting the...

  18. 9 CFR 327.4 - Imported products; foreign certificates required.

    Science.gov (United States)

    2010-01-01

    ... products have been handled in a sanitary manner in this country and are otherwise in compliance with... handled in a sanitary manner, and were prepared under the continuous supervision of an inspector under... delivered by the consignee, or his agent, in the United States to the Program import inspector at the place...

  19. 29 CFR 780.216 - Nursery activities generally and Christmas tree production.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 3 2010-07-01 2010-07-01 false Nursery activities generally and Christmas tree production... Nursery activities generally and Christmas tree production. (a) The employees of a nursery who are engaged... horticultural commodities such as the following are employed in agriculture: (1) Planting seedlings in a nursery...

  20. Mission reliability of semi-Markov systems under generalized operational time requirements

    International Nuclear Information System (INIS)

    Wu, Xiaoyue; Hillston, Jane

    2015-01-01

    Mission reliability of a system depends on specific criteria for mission success. To evaluate the mission reliability of some mission systems that do not need to work normally for the whole mission time, two types of mission reliability for such systems are studied. The first type corresponds to the mission requirement that the system must remain operational continuously for a minimum time within the given mission time interval, while the second corresponds to the mission requirement that the total operational time of the system within the mission time window must be greater than a given value. Based on Markov renewal properties, matrix integral equations are derived for semi-Markov systems. Numerical algorithms and a simulation procedure are provided for both types of mission reliability. Two examples are used for illustration purposes. One is a one-unit repairable Markov system, and the other is a cold standby semi-Markov system consisting of two components. By the proposed approaches, the mission reliability of systems with time redundancy can be more precisely estimated to avoid possible unnecessary redundancy of system resources. - Highlights: • Two types of mission reliability under generalized requirements are defined. • Equations for both types of reliability are derived for semi-Markov systems. • Numerical methods are given for solving both types of reliability. • Simulation procedure is given for estimating both types of reliability. • Verification of the numerical methods is given by the results of simulation

  1. 75 FR 78755 - Notice of Initial Determination Revising the List of Products Requiring Federal Contractor...

    Science.gov (United States)

    2010-12-16

    ... Products Requiring Federal Contractor Certification as to Forced/Indentured Child Labor Pursuant to... products requiring federal contractor certification as to the use of forced or indentured child labor. To.... 13126 (``Prohibition of Acquisition of Products Produced by Forced or Indentured Child Labor''), in...

  2. 76 FR 31365 - Notice of Final Determination Revising the List of Products Requiring Federal Contractor...

    Science.gov (United States)

    2011-05-31

    ... List of Products Requiring Federal Contractor Certification as to Forced or Indentured Child Labor... Contractor Certification as to Forced or Indentured Child Labor.'' This notice adds a product, hand-woven... of the List of Products Requiring Federal Contractor Certification as to Forced or Indentured Child...

  3. 46 CFR 50.25-5 - Products requiring manufacturer or mill certification.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 2 2010-10-01 2010-10-01 false Products requiring manufacturer or mill certification... manufacturer or mill certification. (a) Products required to be certified by a manufacturer or by mill... accepted without referring to its manufacturer or mill certification, if: (1) The product is marked in...

  4. 75 FR 42164 - Notice of Final Determination Updating the List of Products Requiring Federal Contractor...

    Science.gov (United States)

    2010-07-20

    ... List of Products Requiring Federal Contractor Certification as to Forced or Indentured Child Labor... Guidelines for Maintenance of the List of Products Requiring Federal Contractor Certification as to Forced or.... 13126 (``Prohibition of Acquisition of Products Produced by Forced or Indentured Child Labor''), in...

  5. 24 CFR 200.936 - Supplementary specific procedural requirements under HUD building products certification program...

    Science.gov (United States)

    2010-04-01

    ... requirements under HUD building products certification program for solid fuel type room heaters and fireplace... Supplementary specific procedural requirements under HUD building products certification program for solid fuel... fireplace stoves certified under the HUD Building Products Certification Program shall be designed...

  6. 30 CFR 250.195 - What notification does MMS require on the production status of wells?

    Science.gov (United States)

    2010-07-01

    ... the well in a production status. You must confirm oral notification by telefax or e-mail within those... production status of wells? 250.195 Section 250.195 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT... Information and Reporting Requirements § 250.195 What notification does MMS require on the production status...

  7. 40 CFR 158.2160 - Microbial pesticides product performance data requirements.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 23 2010-07-01 2010-07-01 false Microbial pesticides product... AGENCY (CONTINUED) PESTICIDE PROGRAMS DATA REQUIREMENTS FOR PESTICIDES Microbial Pesticides § 158.2160 Microbial pesticides product performance data requirements. Product performance data must be developed for...

  8. 40 CFR 158.210 - Experimental use permit data requirements for product chemistry.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 23 2010-07-01 2010-07-01 false Experimental use permit data requirements for product chemistry. 158.210 Section 158.210 Protection of Environment ENVIRONMENTAL PROTECTION... Experimental use permit data requirements for product chemistry. All product chemistry data, as described in...

  9. Efficient protein production by yeast requires global tuning of metabolism

    DEFF Research Database (Denmark)

    Huang, Mingtao; Bao, Jichen; Hallstrom, Bjorn M.

    2017-01-01

    The biotech industry relies on cell factories for production of pharmaceutical proteins, of which several are among the top-selling medicines. There is, therefore, considerable interest in improving the efficiency of protein production by cell factories. Protein secretion involves numerous...... intracellular processes with many underlying mechanisms still remaining unclear. Here, we use RNA-seq to study the genome-wide transcriptional response to protein secretion in mutant yeast strains. We find that many cellular processes have to be attuned to support efficient protein secretion. In particular...... that by tuning metabolism cells are able to efficiently secrete recombinant proteins. Our findings provide increased understanding of which cellular regulations and pathways are associated with efficient protein secretion....

  10. Legume Seed Production Meeting Market Requirements and Economic Impacts

    DEFF Research Database (Denmark)

    Boelt, Birte; Julier, Bernadette; Karagić, Đura

    2015-01-01

    The seed is the carrier of the genetic improvements brought about by modern plant breeding, and seed production is carried out in accordance with certification systems to guarantee consistent high quality. In forage legumes, breeding efforts are primarily related to the vegetative development...... of the plant, although the commercial success of an agronomically superior cultivar is dependent on a reliable supply of competitively priced seed. In seed production of the three most important forage legumes, alfalfa (Medicago sativa L.), white clover (Trifolium repens L.), and red clover (Trifolium pratense......-pollinated forage legumes it is further highly influenced by environmental conditions and crop management factors. Further investigations into the use of plant growth regulators and an improved understanding of the interaction between pollinators and the seed crop might improve future seed yields. There is likely...

  11. Design requirements for SRB production control system. Volume 4: Implementation

    Science.gov (United States)

    1981-01-01

    The implementation plan which is presented was developed to provide the means for the successful implementation of the automated production control system. There are three factors which the implementation plan encompasses: detailed planning; phased implementation; and user involvement. The plan is detailed to the task level in terms of necessary activities as the system is developed, refined, installed, and tested. These tasks are scheduled, on a preliminary basis, over a two-and-one-half-year time frame.

  12. 28 CFR 51.10 - Requirement of action for declaratory judgment or submission to the Attorney General.

    Science.gov (United States)

    2010-07-01

    ... judgment or submission to the Attorney General. 51.10 Section 51.10 Judicial Administration DEPARTMENT OF... Attorney General. Section 5 requires that, prior to enforcement of any change affecting voting, the... will not be the effect of the change or (b) Make to the Attorney General a proper submission of the...

  13. Identified adjustability dimensions when generating a product specific requirements specification by requirements reuse

    DEFF Research Database (Denmark)

    Hauksdóttir, Dagný; Mortensen, Niels Henrik; Nielsen, Poul Erik

    2014-01-01

    . An extensive state of the art is included to introduce the presented methods related to each adjustability dimensions. The options for implementing each adjustability dimensions in a requirement reuse approach are illustrated along with a discussion regarding the benefits and issues resulting from each option....... This discussion should help practitioners to better understand the possible methods that can be implemented and to design a user friendly and sustainable approach. A case study, describing how the dimensions are incorporated in two requirements reuse approaches, for Danfoss Solar Inverters (SI) and Danfoss...

  14. Oxidation products are increased in patients affected by non-segmental generalized vitiligo.

    Science.gov (United States)

    Vaccaro, Mario; Bagnato, Gianluca; Cristani, Mariateresa; Borgia, Francesco; Spatari, Giovanna; Tigano, Valeria; Saja, Antonina; Guarneri, Fabrizio; Cannavò, Serafinella P; Gangemi, Sebastiano

    2017-08-01

    Several lines of evidence support the relevance of reactive oxygen species (ROS) in vitiligo, but the exact role of glycation and oxidation of macromolecules needs to be better addressed. To investigate the involvement of advanced oxidation protein products (AOPPs) and advanced glycation end-products (AGEs), we performed a case-control association study by spectrofluorimetry and spectrophotometry, in 47 patients with non-segmental generalized vitiligo and 47 age- and sex-matched controls. Significantly higher levels of both AOPPs (p vitiligo patients compared to healthy controls. In vitiligo patients, AGEs and AOPPs serum levels were directly associated with extension, duration of vitiligo, and disease activity. ROS, and in particular AGEs and AOPPs, could represent one of the main biomarkers to assess the onset and progression of vitiligo, due to the potential role as direct inducers of cell damage and also as autoimmunity triggers. Further longitudinal studies involving larger cohorts of patients are required to elucidate the role of oxidation products in the pathogenesis of vitiligo.

  15. Energy requirement for the production of silicon solar arrays

    Science.gov (United States)

    Lindmayer, J.; Wihl, M.; Scheinine, A.; Rosenfield, T.; Wrigley, C. Y.; Morrison, A.; Anderson, J.; Clifford, A.; Lafky, W.

    1977-01-01

    The results of a study to investigate the feasibility of manufacturing photovoltaic solar array modules by the use of energy obtained from similar or identical photovoltaic sources are presented. The primary objective of this investigation was the characterization of the energy requirements of current and developing technologies which comprise the photovoltaic field. For cross-checking the energies of prevailing technologies data were also used and the wide-range assessment of alternative technologies included different refinement methods, various ways of producing light sheets, semicrystalline cells, etc. Energy data are utilized to model the behavior of a future solar breeder plant under various operational conditions.

  16. The safety of food products requires X-ray testing

    International Nuclear Information System (INIS)

    Lardiere, C.

    2017-01-01

    Food safety through standards and regulations imposes food products to be tested for the presence of alien elements. So far metal detectors have been used to detect metal parts, now they have been progressively replaced with X-ray scanners that allow the detection of a lot more contaminants. The improvement of algorithms for image processing combined with the availability of ever more powerful PC have led to the routine use of X-ray testing on industrial processes. Technological progress has made X-ray testing more efficient: while previously a power of 500 W was necessary to cross a 10 cm thickness of water, now only 100 W is necessary. The main advantage of X-ray testing is to be able to test food even packed in metal containers and to detect if the container is deformed. Another advantages is to be able to detect a lot of elements like pieces of glass, small stones or bits of bones. The minimal size to be detected is 0.5 mm for stainless steels and 2 mm for glass or bones. Usually metal detectors are set at the end of the production line just before packaging but in some cases they can be included in the line in order to protect the next machine that intervenes to process the food. (A.C.)

  17. Manual on radiation protection in hospitals and general practice. Basic protection requirements

    International Nuclear Information System (INIS)

    Braestrup, C.B.; Vikterloef, K.J.

    1974-01-01

    The manual as a whole deals with the radiation protection of patients, occupationally exposed persons, and the public. Volume 1, on basic protection requirements, is a general review common to all medical applications of ionizing radiation and radionuclides. Radiation protection is required for patients and staff, and with regard to medical research and chemical trials of new methods; radiation equipment and operating procedures are discussed in connection with diagnostic x-ray installations, x-ray beam therapy, gamma-ray installations for teletherapy, brachytherapy, unsealed sources for therapeutic use, and the diagnostic use of unsealed sources in nuclear medicine. In planning of radiation facilities, attention is paid to levels at which medical care is given, the centralization and decentralization of radiation facilities, diagnostic x-ray facilities and therapy facilities, and nuclear medicine and therapy with unsealed sources. Shielding design is discussed applicable to diagnostic radiology, radiotherapy, nuclear medicine and the therapeutic use of radionuclides. Assignment of responsibilities, legal responsibilities, safety checks, refresher courses and symposia are discussed in the context of organizing radiation protection. Radiation surveys are necessary, and such surveys are described for x-ray and gamma-ray beams, sealed radioactive sources and nuclear medicine. A whole section is devoted to personnel monitoring and health surveillance. An annex gives a list of commonly used radionuclides, another deals with the design of protective shielding

  18. Layer specific and general requirements for ERK/MAPK signaling in the developing neocortex

    Science.gov (United States)

    Xing, Lei; Larsen, Rylan S; Bjorklund, George Reed; Li, Xiaoyan; Wu, Yaohong; Philpot, Benjamin D; Snider, William D; Newbern, Jason M

    2016-01-01

    Aberrant signaling through the Raf/MEK/ERK (ERK/MAPK) pathway causes pathology in a family of neurodevelopmental disorders known as 'RASopathies' and is implicated in autism pathogenesis. Here, we have determined the functions of ERK/MAPK signaling in developing neocortical excitatory neurons. Our data reveal a critical requirement for ERK/MAPK signaling in the morphological development and survival of large Ctip2+ neurons in layer 5. Loss of Map2k1/2 (Mek1/2) led to deficits in corticospinal tract formation and subsequent corticospinal neuron apoptosis. ERK/MAPK hyperactivation also led to reduced corticospinal axon elongation, but was associated with enhanced arborization. ERK/MAPK signaling was dispensable for axonal outgrowth of layer 2/3 callosal neurons. However, Map2k1/2 deletion led to reduced expression of Arc and enhanced intrinsic excitability in both layers 2/3 and 5, in addition to imbalanced synaptic excitation and inhibition. These data demonstrate selective requirements for ERK/MAPK signaling in layer 5 circuit development and general effects on cortical pyramidal neuron excitability. DOI: http://dx.doi.org/10.7554/eLife.11123.001 PMID:26848828

  19. Allocation base of general production costs as optimization of prime costs

    Directory of Open Access Journals (Sweden)

    Levytska I.O.

    2017-03-01

    Full Text Available Qualified management aimed at optimizing financial results is the key factor in today's society. Effective management decisions depend on the necessary information about the costs of production process in all its aspects – their structure, types, accounting policies of reflecting costs. General production costs, the so-called indirect costs that are not directly related to the production process, but provide its functioning in terms of supporting structural divisions and create the necessary conditions of production, play a significant role in calculating prime costs of goods (works, services. However, the accurate estimate of prime costs of goods (works, services should be determined with the value of indirect costs (in other words, general production costs, and properly determined with the base of their allocation. The choice of allocation base of general production costs is the significant moment, depending on the nature of business, which must guarantee fair distribution regarding to the largest share of direct expenses in the total structure of production costs. The study finds the essence of general production costs based on the analysis of key definitions of leading Ukrainian economists. The optimal allocation approach of general production costs is to calculate these costs as direct production costs within each subsidiary division (department separately without selecting a base as the main one to the their total amount.

  20. Attention for speaking: domain-general control from the anterior cingulate cortex in spoken word production

    Directory of Open Access Journals (Sweden)

    Vitoria ePiai

    2013-12-01

    Full Text Available Accumulating evidence suggests that some degree of attentional control is required to regulate and monitor processes underlying speaking. Although progress has been made in delineating the neural substrates of the core language processes involved in speaking, substrates associated with regulatory and monitoring processes have remained relatively underspecified. We report the results of an fMRI study examining the neural substrates related to performance in three attention-demanding tasks varying in the amount of linguistic processing: vocal picture naming while ignoring distractors (picture-word interference, PWI; vocal colour naming while ignoring distractors (Stroop; and manual object discrimination while ignoring spatial position (Simon task. All three tasks had congruent and incongruent stimuli, while PWI and Stroop also had neutral stimuli. Analyses focusing on common activation across tasks identified a portion of the dorsal anterior cingulate cortex that was active in incongruent trials for all three tasks, suggesting that this region subserves a domain-general attentional control function. In the language tasks, this area showed increased activity for incongruent relative to congruent stimuli, consistent with the involvement of domain-general mechanisms of attentional control in word production. The two language tasks also showed activity in anterior-superior temporal gyrus. Activity increased for neutral PWI stimuli (picture and word did not share the same semantic category relative to incongruent (categorically related and congruent stimuli. This finding is consistent with the involvement of language-specific areas in word production, possibly related to retrieval of lexical-semantic information from memory. The current results thus suggest that in addition to engaging language-specific areas for core linguistic processes, speaking also engages the anterior cingulate cortex, a region that is likely implementing domain-general

  1. Process and utility water requirements for cellulosic ethanol production processes via fermentation pathway

    Science.gov (United States)

    The increasing need of additional water resources for energy production is a growing concern for future economic development. In technology development for ethanol production from cellulosic feedstocks, a detailed assessment of the quantity and quality of water required, and the ...

  2. [Precautions of physical performance requirements and test methods during product standard drafting process of medical devices].

    Science.gov (United States)

    Song, Jin-Zi; Wan, Min; Xu, Hui; Yao, Xiu-Jun; Zhang, Bo; Wang, Jin-Hong

    2009-09-01

    The major idea of this article is to discuss standardization and normalization for the product standard of medical devices. Analyze the problem related to the physical performance requirements and test methods during product standard drafting process and make corresponding suggestions.

  3. 78 FR 12329 - Distinguishing Medical Device Recalls From Product Enhancements; Reporting Requirements; Draft...

    Science.gov (United States)

    2013-02-22

    ... medical devices to take timely action to correct violative devices or remove them from the marketplace...] Distinguishing Medical Device Recalls From Product Enhancements; Reporting Requirements; Draft Guidance for... draft guidance entitled ``Distinguishing Medical Device Recalls From Product Enhancements; Reporting...

  4. 9 CFR 381.197 - Imported products; foreign inspection certificates required.

    Science.gov (United States)

    2010-01-01

    ... AND VOLUNTARY INSPECTION AND CERTIFICATION POULTRY PRODUCTS INSPECTION REGULATIONS Imported Poultry... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false Imported products; foreign inspection certificates required. 381.197 Section 381.197 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE...

  5. 75 FR 42315 - Third Party Testing for Certain Children's Products; Carpets and Rugs: Requirements for...

    Science.gov (United States)

    2010-07-21

    ... (ISO)/International Electrotechnical Commission (IEC) Standard 17025:2005, ``General Requirements for... and of the requirements of the ISO/IEC 17025:2005 laboratory accreditation standard is provided in the....org/membersbycategory.html . The accreditation must be to ISO Standard ISO/IEC 17025:2005, ``General...

  6. 28 CFR 65.83 - Assistance required by the Attorney General.

    Science.gov (United States)

    2010-07-01

    ... General. The Attorney General may request assistance from a State or local government in the... of INS, who shall, in turn, certify to the Attorney General, that the number of asylum applications... for asylum in the district. (b) The Attorney General determines that there exist circumstances...

  7. Effects of Using Requirements Catalogs on Effectiveness and Productivity of Requirements Specification in a Software Project Management Course

    Science.gov (United States)

    Fernández-Alemán, José Luis; Carrillo-de-Gea, Juan Manuel; Meca, Joaquín Vidal; Ros, Joaquín Nicolás; Toval, Ambrosio; Idri, Ali

    2016-01-01

    This paper presents the results of two educational experiments carried out to determine whether the process of specifying requirements (catalog-based reuse as opposed to conventional specification) has an impact on effectiveness and productivity in co-located and distributed software development environments. The participants in the experiments…

  8. Kronecker product of Sp(2n) representations using generalized Young tableaux

    International Nuclear Information System (INIS)

    Girardi, G.; Sciarrino, A.; Sorba, P.

    1981-09-01

    Using generalized Young tableaux, we obtain an explicit formula for the reduction of the Kronecker product of irreducible representation of the symplectic groups. This extends a previous work devoted to the case of orthogonal groups

  9. General technical requirements (GTR) for inventory monitoring systems (IMS) for the trilateral initiative

    International Nuclear Information System (INIS)

    Pshakin, Gennady M.; Kuleshov, I.; Shea, T.; Puckett, J.M.; Zhukov, I.; Mangan, Dennis L.; Matter, John C.; Waddoups, I.; Smathers, D.; Abhold, M.E.; Hsue, S.-T.; Chiaro, P.

    2002-01-01

    Pursuant to the Trilateral Initiative, the three parties (The Russian Federation, the United States, and the International Atomic Energy Agency) have been engaged in discussions concerning the structure of reliable monitoring systems for storage facilities having large inventories. The intent of these monitoring systems is to provide the capability for the IAEA to maintain continuity of knowledge in a sufficiently reliable manner that should there be equipment failure, loss of continuity of knowledge would be restricted to a small population of the inventory, and thus reinventory of the stored items would be minimized These facility-specific monitoring systems, referred to as Inventory Monitoring Systems (IMS) are to provide the principal means for the M A to assure that the containers of fissile material remain accounted under the Verification Agreements which are to be concluded between the IAEA and the Russian Federation and the lAEA and the United States for the verification of weapon-origin and other fissile material specified by each State as released from its defense programs. A technical experts working group for inventory monitoring systems has been meeting since Feb- of 2000 to formulate General Technical Requirements (GTR) for Inventory Monitoring Systems for the Trilateral Initiative. Although provisional agreement has been reached by the three parties concerning the GTR, it is considered a living document that can be updated as warranted by the three parties. This paper provides a summary of the GTR as it currently exists.

  10. 77 FR 59418 - Notice of Initial Determination Revising the List of Products Requiring Federal Contractor...

    Science.gov (United States)

    2012-09-27

    ... of products requiring federal contractor certification as to the use of forced or indentured child... DEPARTMENT OF LABOR Notice of Initial Determination Revising the List of Products Requiring Federal Contractor Certification as to Forced/Indentured Child Labor Pursuant to Executive Order 13126...

  11. 49 CFR 661.6 - Certification requirements for procurement of steel or manufactured products.

    Science.gov (United States)

    2010-10-01

    ... § 661.6 Certification requirements for procurement of steel or manufactured products. If steel, iron, or... 49 Transportation 7 2010-10-01 2010-10-01 false Certification requirements for procurement of steel or manufactured products. 661.6 Section 661.6 Transportation Other Regulations Relating to...

  12. 76 FR 61384 - Notice of Initial Determination Revising the List of Products Requiring Federal Contractor...

    Science.gov (United States)

    2011-10-04

    ... Maintenance of the List of Products Requiring Federal Contractor Certification as to Forced or Indentured... DEPARTMENT OF LABOR Notice of Initial Determination Revising the List of Products Requiring Federal Contractor Certification as to Forced/Indentured Child Labor Pursuant to Executive Order 13126...

  13. Air system in the hot cell for injectable radiopharmaceutical production: requirements for personnel and environment safety and protection of the product

    Energy Technology Data Exchange (ETDEWEB)

    Campos, Fabio E.; Araujo, Elaine B., E-mail: fecampos@ipen.b, E-mail: ebaraujo@ipen.b [Instituto de Pesquisas Energeticas e Nucleares (IPEN/CNEN-SP), Sao Paulo, SP (Brazil)

    2009-07-01

    Radiopharmaceuticals are applied in Nuclear Medicine in diagnostic and therapeutic procedures and must be manufactured in accordance with the basic principles of Good Manufacturing Practices (GMP) for sterile pharmaceutical products. In order to prevent the uncontrolled spread of radioactive contamination, the processing of radioactive materials requires an exhausted and shielded special enclosure called hot cell. The quality of air inside the hot cell must be controlled in order to prevent the contamination of the product with particulate material or microorganisms. On the other hand, the hot cell must prevent external contamination with radioactive material. The aim of this work is to discuss the special requirements for hot cells taking in account the national rules for injectable pharmaceutical products and international standards available. Ventilation of radiopharmaceutical production facilities should meet the requirement to prevent the contamination of products and the exposure of working personnel to radioactivity. Positive pressure areas should be used to process sterile products. In general, any radioactivity should handle within specifically designed areas maintained under negative pressures. The production of sterile radioactive products should therefore be carried out under negative pressure surrounded by a positive pressure zone ensuring that appropriate air quality requirements are met. Some of the recent developments in the use of radioisotopes in medical field have also significantly impacted on the evolution of handling facilities. Application of pharmaceutical GMP requirements for air quality and processing conditions in the handling facilities of radioactive pharmaceuticals has led to significant improvements in the construction of isolator-like hot cells and clean rooms with HEPA filtered ventilation and air conditioning (HVAC) systems. Clean grade A (class 100) air quality hot cells are now available commercially, but in a high cost

  14. Air system in the hot cell for injectable radiopharmaceutical production: requirements for personnel and environment safety and protection of the product

    International Nuclear Information System (INIS)

    Campos, Fabio E.; Araujo, Elaine B.

    2009-01-01

    Radiopharmaceuticals are applied in Nuclear Medicine in diagnostic and therapeutic procedures and must be manufactured in accordance with the basic principles of Good Manufacturing Practices (GMP) for sterile pharmaceutical products. In order to prevent the uncontrolled spread of radioactive contamination, the processing of radioactive materials requires an exhausted and shielded special enclosure called hot cell. The quality of air inside the hot cell must be controlled in order to prevent the contamination of the product with particulate material or microorganisms. On the other hand, the hot cell must prevent external contamination with radioactive material. The aim of this work is to discuss the special requirements for hot cells taking in account the national rules for injectable pharmaceutical products and international standards available. Ventilation of radiopharmaceutical production facilities should meet the requirement to prevent the contamination of products and the exposure of working personnel to radioactivity. Positive pressure areas should be used to process sterile products. In general, any radioactivity should handle within specifically designed areas maintained under negative pressures. The production of sterile radioactive products should therefore be carried out under negative pressure surrounded by a positive pressure zone ensuring that appropriate air quality requirements are met. Some of the recent developments in the use of radioisotopes in medical field have also significantly impacted on the evolution of handling facilities. Application of pharmaceutical GMP requirements for air quality and processing conditions in the handling facilities of radioactive pharmaceuticals has led to significant improvements in the construction of isolator-like hot cells and clean rooms with HEPA filtered ventilation and air conditioning (HVAC) systems. Clean grade A (class 100) air quality hot cells are now available commercially, but in a high cost

  15. Organisational determinants of production and efficiency in general practice: a population-based study

    DEFF Research Database (Denmark)

    Rose Olsen, Kim; Gyrd-Hansen, Dorte; Sørensen, Torben Højmark

    2013-01-01

    Shortage of general practitioners (GPs) and an increased political focus on primary care have enforced the interest in efficiency analysis in the Danish primary care sector. This paper assesses the association between organisational factors of general practices and production and efficiency. We a...

  16. Certain new unified integrals associated with the product of generalized Bessel functions

    Directory of Open Access Journals (Sweden)

    Praveen Agarwal

    2016-02-01

    Full Text Available Our focus to presenting two very general integral formulas whose integrands are the integrand given in the Oberhettinger's integral formula and a finite product of the generalized Bessel function of the first kind, which are expressed in terms of the generalized Lauricella functions. Among a large number of interesting and potentially useful special cases of our main results, some integral formulas involving such elementary functions are also considered.

  17. 24 CFR 200.945 - Supplementary specific requirements under the HUD building product standards and certification...

    Science.gov (United States)

    2010-04-01

    ... under the HUD building product standards and certification program for carpet. 200.945 Section 200.945... requirements under the HUD building product standards and certification program for carpet. (a) Applicable.... (b) Labeling. Under the procedures set forth in § 200.935(d)(6) concerning labeling of a product, the...

  18. 24 CFR 200.943 - Supplementary specific requirements under the HUD building product standards and certification...

    Science.gov (United States)

    2010-04-01

    ... under the HUD building product standards and certification program for the grademarking of lumber. 200... Supplementary specific requirements under the HUD building product standards and certification program for the... compliance with the U.S. Department of Commerce Voluntary Product Standard PS 20-94 American Softwood Lumber...

  19. 24 CFR 200.952 - Supplementary specific requirements under the HUD building product standards and certification...

    Science.gov (United States)

    2010-04-01

    ... under the HUD building product standards and certification program for particleboard interior stair... Supplementary specific requirements under the HUD building product standards and certification program for... forth in § 200.935(d)(6) concerning labeling of a product, the administrator's validation mark and the...

  20. 24 CFR 200.940 - Supplementary specific requirements under the HUD building product standards and certification...

    Science.gov (United States)

    2010-04-01

    ... under the HUD building product standards and certification program for sealed insulating glass units... Supplementary specific requirements under the HUD building product standards and certification program for... specific building product certification program. In the case of sealed insulating glass units, testing and...

  1. 24 CFR 200.954 - Supplementary specific requirements under the HUD building product standard and certification...

    Science.gov (United States)

    2010-04-01

    ... under the HUD building product standard and certification program for construction adhesives for wood... § 200.954 Supplementary specific requirements under the HUD building product standard and certification...) concerning labeling of a product, the administrator's validation mark and the manufacturer's certification of...

  2. 15 CFR 715.1 - Annual declaration requirements for production by synthesis of unscheduled discrete organic...

    Science.gov (United States)

    2010-01-01

    ... production by synthesis of unscheduled discrete organic chemicals (UDOCs). 715.1 Section 715.1 Commerce and... DISCRETE ORGANIC CHEMICALS (UDOCs) § 715.1 Annual declaration requirements for production by synthesis of unscheduled discrete organic chemicals (UDOCs). (a) Declaration of production by synthesis of UDOCs for...

  3. Energy taxes and wages in a general equilibrium model of production

    International Nuclear Information System (INIS)

    Thompson, H.

    2000-01-01

    Energy taxes are responsible for a good deal of observed differences in energy prices across states and countries. They alter patterns of production and income distribution. The present paper examines the potential of energy taxes to lower wages in a general equilibrium model of production with capital, labour and energy inputs. (Author)

  4. Examining the Extent of Environmental Compliance Requirements on Mechatronic Products and Their Implementation through Product Lifecycle Management

    Science.gov (United States)

    Jovanovic, Vukica

    2010-01-01

    The present mixed-methods study examined the opinions of industry practitioners related to the implementation of environmental compliance requirements into design and manufacturing processes of mechatronic and electromechanical products. It focused on the environmental standards for mechatronic and electromechanical products and how Product…

  5. 78 FR 4307 - Current Good Manufacturing Practice Requirements for Combination Products

    Science.gov (United States)

    2013-01-22

    ...-2009-N-0435] Current Good Manufacturing Practice Requirements for Combination Products AGENCY: Food and...) is issuing this regulation on the current good manufacturing practice (CGMP) requirements applicable... this subpart? (Sec. 4.2) D. What current good manufacturing practice requirements apply to my...

  6. 21 CFR 111.135 - What quality control operations are required for product complaints?

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 2 2010-04-01 2010-04-01 false What quality control operations are required for... MANUFACTURING, PACKAGING, LABELING, OR HOLDING OPERATIONS FOR DIETARY SUPPLEMENTS Production and Process Control System: Requirements for Quality Control § 111.135 What quality control operations are required for...

  7. 78 FR 12676 - Timing Requirements for the Submission of a Site Assessment Plan (SAP) or General Activities Plan...

    Science.gov (United States)

    2013-02-25

    ...: BOEM-2012-0077] RIN 1010-AD77 Timing Requirements for the Submission of a Site Assessment Plan (SAP) or... would amend the timing requirements for submitting a Site Assessment Plan (SAP) or General Activities... and grants will have a preliminary term of 12 months in which a lessee or grantee must submit a SAP or...

  8. Identifying and prioritizing customer requirements from tractor production by QFD method

    Directory of Open Access Journals (Sweden)

    H Taghizadeh

    2017-05-01

    Full Text Available Introduction Discovering and understanding customer needs and expectations are considered as important factors on customer satisfaction and play vital role to maintain the current activity among its competitors, proceeding and obtaining customer satisfaction which are critical factors to design a successful production; thus the successful organizations must meet their needs containing the quality of the products or services to customers. Quality Function Deployment (QFD is a technique for studying demands and needs of customers which is going to give more emphasis to the customer's interests in this way. The QFD method in general implemented various tools and methods for reaching qualitative goals; but the most important and the main tool of this method is the house of quality diagrams. The Analytic Hierarchy Process (AHP is a famous and common MADM method based on pair wise comparisons used for determining the priority of understudied factors in various studies until now. With considering effectiveness of QFD method to explicating customer's demands and obtaining customer satisfaction, generally, the researchers followed this question's suite and scientific answer: how can QFD explicate real demands and requirements of customers from tractor final production and what is the prioritization of these demands and requirements in view of customers. Accordingly, the aim of this study was to identify and prioritize the customer requirements of Massey Ferguson (MF 285 tractor production in Iran tractor manufacturing company with t- student statistical test, AHP and QFD methods. Materials and Methods Research method was descriptive and statistical population included all of the tractor customers of Tractor Manufacturing Company in Iran from March 2011 to March 2015. The statistical sample size was 171 which are determined with Cochran index. Moreover, 20 experts' opinion has been considered for determining product's technical requirements. Literature

  9. FISPRO: a simplified computer program for general fission product formation and decay calculations

    International Nuclear Information System (INIS)

    Jiacoletti, R.J.; Bailey, P.G.

    1979-08-01

    This report describes a computer program that solves a general form of the fission product formation and decay equations over given time steps for arbitrary decay chains composed of up to three nuclides. All fission product data and operational history data are input through user-defined input files. The program is very useful in the calculation of fission product activities of specific nuclides for various reactor operational histories and accident consequence calculations

  10. Influence of Alcohol and Tobacco Use on Sodium Thiopental Requirements in General Anesthesia: A Retrospective Study of 700 Patients

    OpenAIRE

    Bashir, K. R.; Raman, S.; Knott, V. J.; Bulmer, D. R.; Hurtig, J. B.

    1981-01-01

    Hospital charts of 700 patients who had undergone upper gastrointestinal surgery were reviewed to examine the relationship between alcohol abuse and dose of intravenous sodium thiopental (Pentothal) required to induce general anesthesia. Patients who required a high sodium thiopental dose (greater than 6.08 mg/kg) exhibited a higher incidence of alcoholism, heavy drinking, and heavy smoking, compared to patients who required low sodium thiopental dose (greater than 3.42 mg/kg and less than 4....

  11. 75 FR 42283 - Review of Arbitration Awards; Miscellaneous and General Requirements

    Science.gov (United States)

    2010-07-21

    ... supported the provision of assistance from the Authority's Collaboration and Alternative Dispute Resolution... that ``the requirements and relevant material regarding alternative dispute resolution be set forth... regulation set forth ``the requirements and relevant material regarding alternative dispute resolution...

  12. Innovative product design based on comprehensive customer requirements of different cognitive levels.

    Science.gov (United States)

    Li, Xiaolong; Zhao, Wu; Zheng, Yake; Wang, Rui; Wang, Chen

    2014-01-01

    To improve customer satisfaction in innovative product design, a topology structure of customer requirements is established and an innovative product approach is proposed. The topology structure provides designers with reasonable guidance to capture the customer requirements comprehensively. With the aid of analytic hierarchy process (AHP), the importance of the customer requirements is evaluated. Quality function deployment (QFD) is used to translate customer requirements into product and process design demands and pick out the technical requirements which need urgent improvement. In this way, the product is developed in a more targeted way to satisfy the customers. the theory of innovative problems solving (TRIZ) is used to help designers to produce innovative solutions. Finally, a case study of automobile steering system is used to illustrate the application of the proposed approach.

  13. Innovative Product Design Based on Comprehensive Customer Requirements of Different Cognitive Levels

    Directory of Open Access Journals (Sweden)

    Xiaolong Li

    2014-01-01

    Full Text Available To improve customer satisfaction in innovative product design, a topology structure of customer requirements is established and an innovative product approach is proposed. The topology structure provides designers with reasonable guidance to capture the customer requirements comprehensively. With the aid of analytic hierarchy process (AHP, the importance of the customer requirements is evaluated. Quality function deployment (QFD is used to translate customer requirements into product and process design demands and pick out the technical requirements which need urgent improvement. In this way, the product is developed in a more targeted way to satisfy the customers. the theory of innovative problems solving (TRIZ is used to help designers to produce innovative solutions. Finally, a case study of automobile steering system is used to illustrate the application of the proposed approach.

  14. Conflict Resolution for Product Performance Requirements Based on Propagation Analysis in the Extension Theory

    Directory of Open Access Journals (Sweden)

    Yanwei Zhao

    2014-01-01

    Full Text Available Traditional product data mining methods are mainly focused on the static data. Performance requirements are generally met as possible by finding some cases and changing their structures. However, when one is satisfied with the structures changed, the other effects are not taken into account by analyzing the correlations; that is, design conflicts are not identified and resolved. An approach to resolving the conflict problems is proposed based on propagation analysis in Extension Theory. Firstly, the extension distance is improved to better fit evaluating the similarity among cases, then, a case retrieval method is developed. Secondly, the transformations that can be made on selected cases are formulated by understanding the conflict natures in the different performance requirements, which leads to the extension transformation strategy development for coordinating conflicts using propagation analysis. Thirdly, the effects and levels of propagation are determined by analyzing the performance values before and after the transformations, thus the co-existing conflict coordination strategy of multiple performances is developed. The method has been implemented in a working prototype system for supporting decision-making. And it has been demonstrated the feasible and effective through resolving the conflicts of noise, exhaust, weight and intake pressure for the screw air compressor performance design.

  15. Certain fractional integral formulas involving the product of generalized Bessel functions.

    Science.gov (United States)

    Baleanu, D; Agarwal, P; Purohit, S D

    2013-01-01

    We apply generalized operators of fractional integration involving Appell's function F 3(·) due to Marichev-Saigo-Maeda, to the product of the generalized Bessel function of the first kind due to Baricz. The results are expressed in terms of the multivariable generalized Lauricella functions. Corresponding assertions in terms of Saigo, Erdélyi-Kober, Riemann-Liouville, and Weyl type of fractional integrals are also presented. Some interesting special cases of our two main results are presented. We also point out that the results presented here, being of general character, are easily reducible to yield many diverse new and known integral formulas involving simpler functions.

  16. Certain Fractional Integral Formulas Involving the Product of Generalized Bessel Functions

    Science.gov (United States)

    Baleanu, D.; Agarwal, P.; Purohit, S. D.

    2013-01-01

    We apply generalized operators of fractional integration involving Appell's function F 3(·) due to Marichev-Saigo-Maeda, to the product of the generalized Bessel function of the first kind due to Baricz. The results are expressed in terms of the multivariable generalized Lauricella functions. Corresponding assertions in terms of Saigo, Erdélyi-Kober, Riemann-Liouville, and Weyl type of fractional integrals are also presented. Some interesting special cases of our two main results are presented. We also point out that the results presented here, being of general character, are easily reducible to yield many diverse new and known integral formulas involving simpler functions. PMID:24379745

  17. General Requirements to the Preparation of Tinctures, Decoctions. Dosage of Phytopreparations

    Directory of Open Access Journals (Sweden)

    I.B. Yershovа

    2016-09-01

    Full Text Available The article describes the advantages and disadvantages of using herbal medicine, general information for the collection of medicinal plants. According to the World Health Organization, the classification of herbal medicine is an integral part of traditional medicine. It refers to the variety of metabolic therapy. This treatment meets the requirements of pathogenetic therapy. Currently, more than 30 % of medicines on the pharmaceutical market have herbal origin. According to the World Health Organization, about 80 % of the world population use mainly traditional medicines of natural origin within the framework of primary health care system. Analysis of publications on phytotherapy revealed insufficient coverage of contraindications and side effects of certain plants. This was the basis for opening in our magazine this column, and we wanted to start with what would be the advantages and disadvantages of phytotherapy. Benefits of herbal medi­cine: biological proximity of the active substances of plants and active substances of the body, harmony therapy for the human body, the prolonged effect of herbal medicines after the completion of therapy, the opportunity to prepare a wide variety of different dosage forms, for both indoor and outdoor use, compatibility with many synthetic pharmaceuticals drugs, comprehensive multilateral action of plants, no side effects, simplicity and ease of preparation of herbal remedies at home, the availability for the majority of patients due to the low cost of the medicines. Limitations of herbal medicine: the complexity of the standardization of the treatment effect of herbal drugs, the complexity of establishing a dose, selectivity of diseases, in which typical herbal remedies are prescribed, the risk of poisoning, particularly in self-collection of medicinal plants. The article also provides methods for the preparation of various forms of herbal remedies, dosage for adults and children. With all the advantages of

  18. 27 CFR 17.185 - Requirements for intermediate products and unfinished nonbeverage products.

    Science.gov (United States)

    2010-04-01

    ... nonbeverage products. The manufacturer may choose either method of accounting for such self-manufactured... subsidiary corporations, regardless of any corporate (or other) relationship, and even if the stock of both...

  19. 75 FR 31688 - Third Party Testing for Certain Children's Products; Infant Bath Seats: Requirements for...

    Science.gov (United States)

    2010-06-04

    ... requirements of the ISO/IEC 17025:2005 laboratory accreditation standard is provided in the CPSC staff briefing....html . The accreditation must be to ISO Standard ISO/IEC 17025:2005, ``General Requirements for the... tested by a third party conformity assessment body that was ISO/IEC 17025 accredited by an ILAC-MRA...

  20. 75 FR 35282 - Third Party Testing for Certain Children's Products; Infant Walkers: Requirements for...

    Science.gov (United States)

    2010-06-21

    ... requirements of the ISO/IEC 17025:2005 laboratory accreditation standard is provided in the CPSC staff briefing... to ISO Standard ISO/IEC 17025:2005, ``General Requirements for the Competence of Testing and... tested by a third party conformity assessment body that was ISO/IEC 17025 accredited by an ILAC-MRA...

  1. Open Wilson lines and generalized star product in noncommutative scalar field theories

    International Nuclear Information System (INIS)

    Kiem, Youngjai; Sato, Haru-Tada; Rey, Soo-Jong; Yee, Jung-Tay

    2002-01-01

    Open Wilson line operators and a generalized star product have been studied extensively in noncommutative gauge theories. We show that they also show up in noncommutative scalar field theories as universal structures. We first point out that the dipole picture of noncommutative geometry provides an intuitive argument for the robustness of the open Wilson lines and generalized star products therein. We calculate the one-loop effective action of noncommutative scalar field theory with a cubic self-interaction and show explicitly that the generalized star products arise in the nonplanar part. It is shown that, at the low-energy, large noncommutativity limit, the nonplanar part is expressible solely in terms of the scalar open Wilson line operator and descendants

  2. 40 CFR 63.2450 - What are my general requirements for complying with this subpart?

    Science.gov (United States)

    2010-07-01

    ...., continuous process vents, batch process vents, storage tanks, transfer operations, and waste management units... requirements based on the hierarchy presented in paragraphs (c)(2)(i) through (vi) of this section. For a combined stream, the applicable requirements are specified in the highest-listed paragraph in the hierarchy...

  3. 38 CFR 61.80 - General operation requirements for supportive housing and service centers.

    Science.gov (United States)

    2010-07-01

    ... requirements. (b) Except for such variations as are proposed by the recipient that would not affect compliance... requirements: (1) The structures must be structurally sound so as not to pose any threat to the health and... recipient, to the extent that such entity considers and makes policies and decisions regarding any project...

  4. 42 CFR 436.811 - Medically needy income standard: General requirements.

    Science.gov (United States)

    2010-10-01

    ... THE VIRGIN ISLANDS Financial Requirements for the Medically Needy Medically Needy Income Standard... groups that meets the requirements of this section. (b) The income standard must take into account the... the State's covered medically needy group or groups of individuals under § 436.301. (d) The income...

  5. Physical environment. [environmental impact statement required for general aviation airport construction

    Science.gov (United States)

    1975-01-01

    Environmental legislation affecting airports and the more common environmental effects resulting from airport construction are discussed with special emphasis on general aviation airports. The discussion is focused on the regulation of noise, pollution, and water quality.

  6. 76 FR 73644 - Announcement of Requirements and Registration for the United States Surgeon General's Healthy...

    Science.gov (United States)

    2011-11-29

    ..., excessive alcohol use) and these chronic illnesses have been well established. The Surgeon General's Vision... computer, a mobile device (e.g., mobile phone, portable sensor, etc.), console, or any platform broadly...

  7. Design requirements for SRB production control system. Volume 3: Package evaluation, modification and hardware

    Science.gov (United States)

    1981-01-01

    The software package evaluation was designed to analyze commercially available, field-proven, production control or manufacturing resource planning management technology and software package. The analysis was conducted by comparing SRB production control software requirements and conceptual system design to software package capabilities. The methodology of evaluation and the findings at each stage of evaluation are described. Topics covered include: vendor listing; request for information (RFI) document; RFI response rate and quality; RFI evaluation process; and capabilities versus requirements.

  8. Defining project scenarios for the agile requirements engineering product-line development questionnaire

    OpenAIRE

    Feng, Kunwu; Lempert, Meli; Tang, Yan; Tian, Kun; Cooper, Kendra M.L.; Franch Gutiérrez, Javier

    2007-01-01

    Current agile methods are focused on practices of small, rapid developing and iteration, more people oriented, less documentation projects, and the use of the methods in large, product line projects are somehow difficult. UTD and GESSI have started a project to develop an expert system that can assist a requirements enginer in selecting a requirements engineering process that is well suited for their project, in particular with respect to the use of agile and product line engineering methods....

  9. Developing a survey to collect expertise in agile product line requirements engineering processes

    OpenAIRE

    Feng, Kunwu; Lempert, Meli; Tang, Yan; Tian, Kun; Cooper, Kendra M.L.; Franch Gutiérrez, Javier

    2007-01-01

    Current agile methods are focused on practices of small, rapid developing and iteration, more people oriented, less documentation projects, and the use of the methods in large, product line projects are somehow difficult. UTD and GESSI have started a project to develop an expert system that can assist a requirements enginer in selecting a requirements engineering process that is well suited for their project, in particular with respect to the use of agile and product line engineering methods....

  10. 29 CFR 2700.5 - General requirements for pleadings and other documents; status or informational requests.

    Science.gov (United States)

    2010-07-01

    ... which enter commerce or has operations or products that affect commerce. Jurisdictional facts that are... digits of social security numbers, financial account numbers, driver's license numbers, or other personal...

  11. 77 FR 60056 - Shippers-General Requirements for Shipments and Packagings

    Science.gov (United States)

    2012-10-02

    ...) Plant and animal waste regulated by the Animal and Plant Health Inspection Service (APHIS); (iii) Waste...; (vii) Rejected or recalled health care products; (viii) Documents intended for destruction in...

  12. 40 CFR 158.2070 - Biochemical pesticides product performance data requirements.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 23 2010-07-01 2010-07-01 false Biochemical pesticides product performance data requirements. 158.2070 Section 158.2070 Protection of Environment ENVIRONMENTAL PROTECTION... efficacy data unless the pesticide product bears a claim to control public health pests, such as pest...

  13. 49 CFR 1300.5 - Additional publication requirement for agricultural products and fertilizer.

    Science.gov (United States)

    2010-10-01

    ... RAIL COMMON CARRIAGE § 1300.5 Additional publication requirement for agricultural products and....C. 75, and all products thereof) and fertilizer, a rail carrier shall publish, make available, and... identification of the changes, the nature of those changes and their effective dates. (c) A rail carrier must...

  14. 15 CFR 713.4 - Advance declaration requirements for additionally planned production, processing, or consumption...

    Science.gov (United States)

    2010-01-01

    ... additionally planned production, processing, or consumption of Schedule 2 chemicals. 713.4 Section 713.4..., processing, or consumption of Schedule 2 chemicals. (a) Declaration requirements for additionally planned activities. (1) You must declare additionally planned production, processing, or consumption of Schedule 2...

  15. 48 CFR 252.225-7024 - Requirement for products or services from Iraq or Afghanistan.

    Science.gov (United States)

    2010-10-01

    ... or services from Iraq or Afghanistan. 252.225-7024 Section 252.225-7024 Federal Acquisition... products or services from Iraq or Afghanistan. As prescribed in 225.7703-5(b), use the following clause: Requirement for Products or Services From Iraq or Afghanistan (SEP 2008) (a) Definitions. As used in this...

  16. Weapon System Requirements: Detailed Systems Engineering Prior to Product Development Positions Programs for Success

    Science.gov (United States)

    2016-11-01

    modified, replaced, or sustained by consumers or different manufacturers in addition to the manufacturer that developed the system. It also allows...WEAPON SYSTEM REQUIREMENTS Detailed Systems Engineering Prior to Product Development Positions Programs for Success...Engineering Prior to Product Development Positions Programs for Success Why GAO Did This Study Cost and schedule growth in DOD major defense

  17. 14 CFR 183.63 - Continuing requirements: Products, parts or appliances.

    Science.gov (United States)

    2010-01-01

    ... appliances. 183.63 Section 183.63 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF... Designation Authorization § 183.63 Continuing requirements: Products, parts or appliances. For any approval or certificate for a product, part or appliance issued under the authority of this subpart, or under the...

  18. 28 CFR 16.22 - General prohibition of production or disclosure in Federal and State proceedings in which the...

    Science.gov (United States)

    2010-07-01

    ... 28 Judicial Administration 1 2010-07-01 2010-07-01 false General prohibition of production or... Judicial Administration DEPARTMENT OF JUSTICE PRODUCTION OR DISCLOSURE OF MATERIAL OR INFORMATION Production or Disclosure in Federal and State Proceedings § 16.22 General prohibition of production or...

  19. Generalized coherent state approach to star products and applications to the fuzzy sphere

    International Nuclear Information System (INIS)

    Alexanian, G.; Pinzul, A.; Stern, A.

    2001-01-01

    We construct a star product associated with an arbitrary two-dimensional Poisson structure using generalized coherent states on the complex plane. From our approach one easily recovers the star product for the fuzzy torus, and also one for the fuzzy sphere. For the latter we need to define the 'fuzzy' stereographic projection to the plane and the fuzzy sphere integration measure, which in the commutative limit reduce to the usual formulae for the sphere

  20. Preparedness and Response for a Nuclear or Radiological Emergency. General Safety Requirements (Chinese Edition)

    International Nuclear Information System (INIS)

    2016-01-01

    This publication, jointly sponsored by the FAO, IAEA, ICAO, ILO, IMO, INTERPOL, OECD/NEA, PAHO, CTBTO, UNEP, OCHA, WHO and WMO, is the new edition establishing the requirements for preparedness and response for a nuclear or radiological emergency which takes into account the latest experience and developments in the area. It supersedes the previous edition of the Safety Requirements for emergency preparedness and response, Safety Standards Series No. GS-R-2, which was published in 2002. This publication establishes the requirements for ensuring an adequate level of preparedness and response for a nuclear or radiological emergency, irrespective of its cause. These Safety Requirements are intended to be used by governments, emergency response organizations, other authorities at the local, regional and national levels, operating organizations and the regulatory body as well as by relevant international organizations at the international level.

  1. Preparedness and Response for a Nuclear or Radiological Emergency. General Safety Requirements (Arabic Edition)

    International Nuclear Information System (INIS)

    2016-01-01

    This publication, jointly sponsored by the FAO, IAEA, ICAO, ILO, IMO, INTERPOL, OECD/NEA, PAHO, CTBTO, UNEP, OCHA, WHO and WMO, is the new edition establishing the requirements for preparedness and response for a nuclear or radiological emergency which takes into account the latest experience and developments in the area. It supersedes the previous edition of the Safety Requirements for emergency preparedness and response, Safety Standards Series No. GS-R-2, which was published in 2002. This publication establishes the requirements for ensuring an adequate level of preparedness and response for a nuclear or radiological emergency, irrespective of its cause. These Safety Requirements are intended to be used by governments, emergency response organizations, other authorities at the local, regional and national levels, operating organizations and the regulatory body as well as by relevant international organizations at the international level.

  2. Preparedness and Response for a Nuclear or Radiological Emergency. General Safety Requirements (Russian Edition)

    International Nuclear Information System (INIS)

    2016-01-01

    This publication, jointly sponsored by the FAO, IAEA, ICAO, ILO, IMO, INTERPOL, OECD/NEA, PAHO, CTBTO, UNEP, OCHA, WHO and WMO, is the new edition establishing the requirements for preparedness and response for a nuclear or radiological emergency which takes into account the latest experience and developments in the area. It supersedes the previous edition of the Safety Requirements for emergency preparedness and response, Safety Standards Series No. GS-R-2, which was published in 2002. This publication establishes the requirements for ensuring an adequate level of preparedness and response for a nuclear or radiological emergency, irrespective of its cause. These Safety Requirements are intended to be used by governments, emergency response organizations, other authorities at the local, regional and national levels, operating organizations and the regulatory body as well as by relevant international organizations at the international level.

  3. 50 CFR 13.12 - General information requirements on applications for permits.

    Science.gov (United States)

    2010-10-01

    ... available, occupation, and any business, agency, organizational, or institutional affiliation associated... permits, together with any additional justification, including supporting documentation as required by the... permit Section Importation at nondesignated ports: Scientific 14.31 Deterioration prevention 14.32...

  4. Intimate terrorism and situational couple violence in general surveys: ex-spouses required.

    Science.gov (United States)

    Johnson, Michael P; Leone, Janel M; Xu, Yili

    2014-02-01

    In this article, we argue that past efforts to distinguish among types of intimate partner violence in general survey data have committed a critical error--using data on current spouses to develop operationalizations of intimate terrorism and situational couple violence. We use ex-spouse data from the National Violence Against Women Survey (NVAWS) to develop new operationalizations. We then demonstrate that NVAWS current spouse data contain little intimate terrorism; we argue that this is likely to be the case for all general surveys. In addition, the ex-spouse data confirm past findings regarding a variety of differences between intimate terrorism and situational couple violence, including those predicted by feminist theories.

  5. Design requirements for SRB production control system. Volume 1: Study background and overview

    Science.gov (United States)

    1981-01-01

    The solid rocket boosters assembly environment is described in terms of the contraints it places upon an automated production control system. The business system generated for the SRB assembly and the computer system which meets the business system requirements are described. The selection software process and modifications required to the recommended software are addressed as well as the hardware and configuration requirements necessary to support the system.

  6. Epstein-Barr Virus BKRF4 Gene Product Is Required for Efficient Progeny Production.

    Science.gov (United States)

    Masud, H M Abdullah Al; Watanabe, Takahiro; Yoshida, Masahiro; Sato, Yoshitaka; Goshima, Fumi; Kimura, Hiroshi; Murata, Takayuki

    2017-12-01

    Epstein-Barr virus (EBV), a member of human gammaherpesvirus, infects mainly B cells. EBV has two alternative life cycles, latent and lytic, and is reactivated occasionally from the latent stage to the lytic cycle. To combat EBV-associated disorders, understanding the molecular mechanisms of the EBV lytic replication cycle is also important. Here, we focused on an EBV lytic gene, BKRF4. Using our anti-BKRF4 antibody, we revealed that the BKRF4 gene product is expressed during the lytic cycle with late kinetics. To characterize the role of BKRF4, we constructed BKRF4-knockout mutants using the bacterial artificial chromosome (BAC) and CRISPR/Cas9 systems. Although disruption of the BKRF4 gene had almost no effect on viral protein expression and DNA synthesis, it significantly decreased progeny virion levels in HEK293 and Akata cells. Furthermore, we show that BKRF4 is involved not only in production of progeny virions but also in increasing the infectivity of the virus particles. Immunoprecipitation assays revealed that BKRF4 interacted with a virion protein, BGLF2. We showed that the C-terminal region of BKRF4 was critical for this interaction and for efficient progeny production. Immunofluorescence analysis revealed that BKRF4 partially colocalized with BGLF2 in the nucleus and perinuclear region. Finally, we showed that BKRF4 is a phosphorylated, possible tegument protein and that the EBV protein kinase BGLF4 may be important for this phosphorylation. Taken together, our data suggest that BKRF4 is involved in the production of infectious virions. IMPORTANCE Although the latent genes of EBV have been studied extensively, the lytic genes are less well characterized. This study focused on one such lytic gene, BKRF4, which is conserved only among gammaherpesviruses (ORF45 of Kaposi's sarcoma-associated herpesvirus or murine herpesvirus 68). After preparing the BKRF4 knockout virus using B95-8 EBV-BAC, we demonstrated that the BKRF4 gene was involved in infectious

  7. 77 FR 12845 - Announcement of Requirements and Registration for Surgeon General's (SG) Youth Video Contest

    Science.gov (United States)

    2012-03-02

    ... of the Contest and their immediate family (spouse, parents and step-parents, siblings and step-siblings, and children and step- children) and household members (people who share the same residence at... conjunction with the launch of the new SG Report, the Surgeon General will be releasing a Consumer Piece in...

  8. 40 CFR 270.14 - Contents of part B: General requirements.

    Science.gov (United States)

    2010-07-01

    ..., and engineering studies shall be certified by a qualified Professional Engineer. For post-closure... § 264.1 provides otherwise: (1) A general description of the facility. (2) Chemical and physical... atmosphere. (9) A description of precautions to prevent accidental ignition or reaction of ignitable...

  9. 38 CFR 59.130 - General requirements for all State home facilities.

    Science.gov (United States)

    2010-07-01

    ... design and construct the project to provide sufficient space and equipment in dining, health services... safety of participants, personnel and the public. (b) A State home must meet the general conditions of..., including the Uniform Federal Accessibility Standards (UFAS) (24 CFR part 40, appendix A), during the design...

  10. Applying CBR to machine tool product configuration design oriented to customer requirements

    Science.gov (United States)

    Wang, Pengjia; Gong, Yadong; Xie, Hualong; Liu, Yongxian; Nee, Andrew Yehching

    2017-01-01

    Product customization is a trend in the current market-oriented manufacturing environment. However, deduction from customer requirements to design results and evaluation of design alternatives are still heavily reliant on the designer's experience and knowledge. To solve the problem of fuzziness and uncertainty of customer requirements in product configuration, an analysis method based on the grey rough model is presented. The customer requirements can be converted into technical characteristics effectively. In addition, an optimization decision model for product planning is established to help the enterprises select the key technical characteristics under the constraints of cost and time to serve the customer to maximal satisfaction. A new case retrieval approach that combines the self-organizing map and fuzzy similarity priority ratio method is proposed in case-based design. The self-organizing map can reduce the retrieval range and increase the retrieval efficiency, and the fuzzy similarity priority ratio method can evaluate the similarity of cases comprehensively. To ensure that the final case has the best overall performance, an evaluation method of similar cases based on grey correlation analysis is proposed to evaluate similar cases to select the most suitable case. Furthermore, a computer-aided system is developed using MATLAB GUI to assist the product configuration design. The actual example and result on an ETC series machine tool product show that the proposed method is effective, rapid and accurate in the process of product configuration. The proposed methodology provides a detailed instruction for the product configuration design oriented to customer requirements.

  11. Governmental, Legal and Regulatory Framework for Safety. General Safety Requirements. Part 1, Revision 1 (Chinese Edition)

    International Nuclear Information System (INIS)

    2016-01-01

    This publication establishes requirements in respect of the governmental, legal and regulatory framework for safety. It covers the essential aspects of the framework for establishing a regulatory body and taking other actions necessary to ensure the effective regulatory control of facilities and activities utilized for peaceful purposes. Other responsibilities and functions, such as liaison within the global safety regime and on support services for safety (including radiation protection), emergency preparedness and response, nuclear security, and the State system of accounting for and control of nuclear material, are also covered. A review of Safety Requirements publications was commenced in 2011 following the accident in the Fukushima Daiichi nuclear power plant in Japan. The review revealed no significant areas of weakness and resulted in just a small set of amendments to strengthen the requirements and facilitate their implementation, which are contained in the present publication.

  12. Hazardous Waste Cleanup: Caribe General Electric Product in Rio Piedras, Puerto Rico

    Science.gov (United States)

    The Caribe General Electric Product facility (GE Río Piedras) covers approximately 4 acres and is situated on the northern coastal plain in a relatively flat industrial/urban area of Río Piedras with an elevation between 20 and 40 feet above mean sea leve

  13. 49 CFR 174.82 - General requirements for the handling of placarded rail cars, transport vehicles, freight...

    Science.gov (United States)

    2010-10-01

    ... rail cars, transport vehicles, freight containers, and bulk packages. 174.82 Section 174.82... Placarded Rail Cars, Transport Vehicles and Freight Containers § 174.82 General requirements for the handling of placarded rail cars, transport vehicles, freight containers, and bulk packages. (a) Unless...

  14. 42 CFR 84.159 - Man tests for gases and vapors; supplied-air respirators; general performance requirements.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Man tests for gases and vapors; supplied-air respirators; general performance requirements. 84.159 Section 84.159 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES OCCUPATIONAL SAFETY AND HEALTH RESEARCH AND RELATED ACTIVITIES APPROVAL OF RESPIRATORY PROTECTIVE DEVICES...

  15. 21 CFR 1271.80 - What are the general requirements for donor testing?

    Science.gov (United States)

    2010-04-01

    ... ADMINISTRATION HUMAN CELLS, TISSUES, AND CELLULAR AND TISSUE-BASED PRODUCTS Donor Eligibility § 1271.80 What are... mother instead of a specimen from the donor. (b) Timing of specimen collection. You must collect the donor specimen for testing at the time of recovery of cells or tissue from the donor; or up to 7 days...

  16. 40 CFR 80.65 - General requirements for refiners and importers.

    Science.gov (United States)

    2010-07-01

    ... to all gasoline produced, imported, transported, stored, sold, or dispensed: (1) At any location... gasoline or RBOB it produces or imports, shall meet: (i) Those standards and requirements it designated... importer of gasoline shall designate the gasoline it produces or imports as follows: (1) All gasoline...

  17. 21 CFR 1240.80 - General requirements for water for drinking and culinary purposes.

    Science.gov (United States)

    2010-04-01

    ... culinary purposes. 1240.80 Section 1240.80 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF... requirements for water for drinking and culinary purposes. Only potable water shall be provided for drinking and culinary purposes by any operator of a conveyance engaged in interstate traffic, except as...

  18. 75 FR 29420 - Revision of LNG and LHG Waterfront Facility General Requirements

    Science.gov (United States)

    2010-05-26

    ... of that document are key elements of the risk management process. Coast Guard review ensures that the... management strategies; and (v) Resource needs for maritime safety, security, and response. (g) The Follow-on... requirements until the collection is approved by the Office of Management and Budget (OMB). When OMB approves...

  19. 49 CFR 172.302 - General marking requirements for bulk packagings.

    Science.gov (United States)

    2010-10-01

    ... rail cars; (2) Have a width of at least 4.0 mm (0.16 inch) and a height of at least 25 mm (one inch... with a proper shipping name, common name or identification number as required by this subpart must... “NITRIC OXIDE” need not be remarked “NITRIC OXIDE, COMPRESSED”. (g) A rail car, freight container, truck...

  20. 40 CFR 63.11173 - What are my general requirements for complying with this subpart?

    Science.gov (United States)

    2010-07-01

    ... of Heating, Refrigerating, and Air-Conditioning Engineers (ASHRAE) Method 52.1, “Gravimetric and Dust...-atomizing methods may also be used. (5) As provided in § 63.6(g), we, the U.S. Environmental Protection...) Environmental compliance with the requirements of this subpart. (3) A description of the methods to be used at...

  1. 30 CFR 816.71 - Disposal of excess spoil: General requirements.

    Science.gov (United States)

    2010-07-01

    ... does not slake in water or degrade to soil material, and which is free of coal, clay or other... of the soil. (2) Excess spoil shall be transported and placed in a controlled manner in horizontal... outslope of the fill if required for stability, control of erosion, to conserve soil moisture, or to...

  2. 30 CFR 817.71 - Disposal of excess spoil: General requirements.

    Science.gov (United States)

    2010-07-01

    ... does not slake in water or degrade to soil materials, and which is free of coal, clay or other... of the soil. (2) Excess spoil shall be transported and placed in a controlled manner in horizontal... outslope of the fill if required for stability, control of erosion, to conserve soil moisture, or to...

  3. 42 CFR 436.840 - Medically needy resource standard: General requirements.

    Science.gov (United States)

    2010-10-01

    ... THE VIRGIN ISLANDS Financial Requirements for the Medically Needy Medically Needy Resource Standard... eligibility under the cash assistance programs that are related to the State's covered medically needy group or groups of individuals under § 436.301. (b) The resource standard established under paragraph (a...

  4. General laws of competition duel and universal requirements to technical-tactic fitness of elite wrestlers

    Directory of Open Access Journals (Sweden)

    G.V. Korobeynikov

    2016-02-01

    Full Text Available Purpose: to determine and formulate general technical-tactic laws (rules of competition duel in modern free style wrestling. Material: competition functioning of free style wrestlers at Olympic Games has been analyzed. Results of authors’ own pedagogic observations and advanced experience of free style wrestling specialists have been generalized. Results: it was found that victory in duel can be resulted only from attacking tactic of duel. It was determined that wrestlers’ activity (quantity of actual attacks in unit of time varies from 1 to 2.2 attacks per minute. Reliability of attack (ratio of quantity of assessed attacks to quantity of actually fulfilled attacks is within 0.33-0.63. Reliability of defense (ratio of quantity of successfully repelled opponent’s attacks to general quantity of his actual attacks is from 0.55-0.78. Efficiency of fighting in stance is within 0.6-1.3 points per minute. Efficiency of ground fighting is 1.3-2.3 points per minute. Conclusions: coach shall bring the formulated laws in compliance with specificity of his functioning and consider them, when planning training process of junior wrestlers.

  5. Evaluation and decision of products conceptual design schemes based on customer requirements

    International Nuclear Information System (INIS)

    Huang, Hong Zhong; Li, Yan Feng; Liu, Yu; Wang, Zhonglai; Liu, Wenhai

    2011-01-01

    Within the competitive market environment, understanding customer requirements is crucial for all corporations to obtain market share and survive competition. Only the products exactly meeting customer requirements can win in the market place. Therefore, customer requirements play a very important role in the evaluation and decision process of conceptual design schemes of products. In this paper, an evaluation and decision method based on customer requirements is presented. It utilizes the importance of customer requirements, the satisfaction degree of each evaluation metric to the specification, and an evaluation metric which models customer requirements to evaluate the satisfaction degree of each design scheme to specific customer requirements via the proposed BP neural networks. In the evaluation and decision process, fuzzy sets are used to describe the importance of customer requirements, the relationship between customer requirements and evaluation metrics, the satisfaction degree of each scheme to customer requirements, and the crisp set is used to describe the satisfaction degree of each metric to specifications. The effectiveness of the proposed method is demonstrated by an example of front suspension fork design of mountain bikes

  6. Evaluation and decision of products conceptual design schemes based on customer requirements

    Energy Technology Data Exchange (ETDEWEB)

    Huang, Hong Zhong; Li, Yan Feng; Liu, Yu; Wang, Zhonglai [University of Electronic Science and Technology of China, Sichuan (China); Liu, Wenhai [2China Science Patent Trademark Agents Ltd., Beijing (China)

    2011-09-15

    Within the competitive market environment, understanding customer requirements is crucial for all corporations to obtain market share and survive competition. Only the products exactly meeting customer requirements can win in the market place. Therefore, customer requirements play a very important role in the evaluation and decision process of conceptual design schemes of products. In this paper, an evaluation and decision method based on customer requirements is presented. It utilizes the importance of customer requirements, the satisfaction degree of each evaluation metric to the specification, and an evaluation metric which models customer requirements to evaluate the satisfaction degree of each design scheme to specific customer requirements via the proposed BP neural networks. In the evaluation and decision process, fuzzy sets are used to describe the importance of customer requirements, the relationship between customer requirements and evaluation metrics, the satisfaction degree of each scheme to customer requirements, and the crisp set is used to describe the satisfaction degree of each metric to specifications. The effectiveness of the proposed method is demonstrated by an example of front suspension fork design of mountain bikes.

  7. Challenges in balancing the amount of solution information in requirement specifications for embedded products

    DEFF Research Database (Denmark)

    Savolainen, Juha; Hauksdóttir, Dagný; Mannion, Mike

    2013-01-01

    customers have such intimate knowledge of their products that their requirements tend to be very specific, and if the customer knows the exact solution needed that naturally will reduce the cost of the requirements elicitation as well as design activities. Practitioners are challenged to understand when......Requirements are traditionally viewed as being free of the details of an envisioned solution and specified using purely problem domain entities. Preventing premature design in the requirements permits the available design space not to be restricted too early which might inhibit innovative designs....... In practice, on many industrial projects, separating the problem and solution domain entities can be difficult, and arguably there are benefits for not doing so. Many customers feel more confident describing their requirements, often as the difference between the existing products and their needs, some...

  8. New legal requirements for submission of product information to poisons centres in EU member states.

    Science.gov (United States)

    de Groot, Ronald; Brekelmans, Pieter; Desel, Herbert; de Vries, Irma

    2018-01-01

    In the past eight years, the European Association of Poisons Centres and Clinical Toxicologists (EAPCCT) has been intensively involved in a European Commission led process to develop EU legislation on the information of hazardous products that companies have to notify to EU Poisons Centres (or equivalent "appointed bodies"). As a result of this process, the Commission adopted Regulation (EU) No 2017/542, amending the CLP Regulation by adding an Annex on harmonised product submission requirements. Harmonised mixture information requirements: Detailed and consistent information on the composition of the hazardous product will become available to EU Poisons Centres (PC). The information will be submitted by companies to PCs (or equivalent "appointed bodies") using a web-based software application or in-house software. Two new important features are introduced. Firstly, to be able to rapidly identify the product formula, a Unique Formula Identifier (UFI) on the product label links to the submitted information. Secondly, for better comparability of reports on poisonings between EU member states, a harmonised Product Categorisation System will specify the intended use of a product. Rapid product identification and availability of detailed composition information will lead to timely and adequate medical intervention. This may lead to considerable reduction in healthcare costs. Additionally, for companies trading across the EU, costs of submission of this information will be reduced significantly. Next steps: From 2017, an implementation period has started, consisting of a three-year period for stakeholders to implement the new requirements, followed by a gradual applicability for consumer products (2020), professional products (2021) and industrial use-only products (2024). Technical tools to generate the electronic format and the UFI together with guidance documents are expected to be made available by the end of 2017 by the European Chemicals Agency (ECHA). Guidance on

  9. Common display performance requirements for military and commercial aircraft product lines

    Science.gov (United States)

    Hoener, Steven J.; Behrens, Arthur J.; Flint, John R.; Jacobsen, Alan R.

    2001-09-01

    Obtaining high quality Active Matrix Liquid Crystal (AMLCD) glass to meet the needs of the commercial and military aerospace business is a major challenge, at best. With the demise of all domestic sources of AMLCD substrate glass, the industry is now focused on overseas sources, which are primarily producing glass for consumer electronics. Previous experience with ruggedizing commercial glass leads to the expectation that the aerospace industry can leverage off the commercial market. The problem remains, while the commercial industry is continually changing and improving its products, the commercial and military aerospace industries require stable and affordable supplies of AMLCD glass for upwards of 20 years to support production and maintenance operations. The Boeing Engineering and Supplier Management Process Councils have chartered a group of displays experts from multiple aircraft product divisions within the Boeing Company, the Displays Process Action Team (DPAT), to address this situation from an overall corporate perspective. The DPAT has formulated a set of Common Displays Performance Requirements for use across the corporate line of commercial and military aircraft products. Though focused on the AMLCD problem, the proposed common requirements are largely independent of display technology. This paper describes the strategy being pursued within the Boeing Company to address the AMLCD supply problem and details the proposed implementation process, centered on common requirements for both commercial and military aircraft displays. Highlighted in this paper are proposed common, or standard, display sizes and the other major requirements established by the DPAT, along with the rationale for these requirements.

  10. Informing General CSCW Product Development through Cooperative Design in Specific Work Domains

    DEFF Research Database (Denmark)

    Grønbæk, Kaj; Mogensen, Preben Holst

    1997-01-01

    sharing of materials in the engineering domain. In our project, a single engineering company (Great Belt Link Ltd.) was chosen as the user organization. The paper summarizes the process from observational studies, over a future workshop and cooperative prototyping activities, to a pilot installation. We...... describe how these activities informed the general hypermedia framework and application design. Use scenarios and prototypes with example data from the users‘ daily work were used as sources both to trigger design ideas and new insights regarding work practice. Common participants in specific activities...... and general development activities supported transfer of work domain knowledge into general features of the product being developed. Mutual challenging characterized the interaction between specific cooperative analysis and design activities and general development activities. Prototypes, scenarios, materials...

  11. Does caries risk assessment predict the incidence of caries for special needs patients requiring general anesthesia?

    Science.gov (United States)

    Chang, Juhea; Kim, Hae-Young

    2014-11-01

    The aim of this study was to correlate the caries-related variables of special needs patients to the incidence of new caries. Data for socio-demographic information and dental and general health status were obtained from 110 patients treated under general anesthesia because of their insufficient co-operation. The Cariogram program was used for risk assessment and other caries-related variables were also analyzed. Within a defined follow-up period (16.3 ± 9.5 months), 64 patients received dental examinations to assess newly developed caries. At baseline, the mean (SD) values of the DMFT (decayed, missing and filled teeth) and DT (decayed teeth) for the total patients were 9.2 (6.5) and 5.8 (5.3), respectively. During the follow-up period, new caries occurred in 48.4% of the patients and the mean value (SD) of the increased DMFT (iDMFT) was 2.1 (4.2). The patients with a higher increment of caries (iDMFT ≥3) showed significantly different caries risk profiles compared to the other patients (iDMFT dentistry. Past caries experience and inadequate oral hygiene maintenance were largely related to caries development in special needs patients.

  12. Governmental, Legal and Regulatory Framework for Safety. General Safety Requirements. Part 1

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2010-09-15

    The objective of this publication is to establish requirements in respect of the governmental, legal and regulatory framework for safety. It covers the essential aspects of the framework for establishing a regulatory body and taking other actions necessary to ensure the effective regulatory control of facilities and activities utilized for peaceful purposes. Other responsibilities and functions, such as liaison within the global safety regime and on support services for safety (including radiation protection), emergency preparedness and response, nuclear security, and the State system of accounting for and control of nuclear material, are also covered.

  13. Governmental, Legal and Regulatory Framework for Safety. General Safety Requirements. Part 1 (Arabic Edition)

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2010-09-15

    The objective of this publication is to establish requirements in respect of the governmental, legal and regulatory framework for safety. It covers the essential aspects of the framework for establishing a regulatory body and taking other actions necessary to ensure the effective regulatory control of facilities and activities utilized for peaceful purposes. Other responsibilities and functions, such as liaison within the global safety regime and on support services for safety (including radiation protection), emergency preparedness and response, nuclear security, and the State system of accounting for and control of nuclear material, are also covered.

  14. Governmental, Legal and Regulatory Framework for Safety. General Safety Requirements. Part 1 (Spanish Edition)

    International Nuclear Information System (INIS)

    2010-01-01

    The objective of this publication is to establish requirements in respect of the governmental, legal and regulatory framework for safety. It covers the essential aspects of the framework for establishing a regulatory body and taking other actions necessary to ensure the effective regulatory control of facilities and activities utilized for peaceful purposes. Other responsibilities and functions, such as liaison within the global safety regime and on support services for safety (including radiation protection), emergency preparedness and response, nuclear security, and the State system of accounting for and control of nuclear material, are also covered

  15. Governmental, Legal and Regulatory Framework for Safety. General Safety Requirements. Part 1 (French Edition)

    International Nuclear Information System (INIS)

    2010-01-01

    The objective of this publication is to establish requirements in respect of the governmental, legal and regulatory framework for safety. It covers the essential aspects of the framework for establishing a regulatory body and taking other actions necessary to ensure the effective regulatory control of facilities and activities utilized for peaceful purposes. Other responsibilities and functions, such as liaison within the global safety regime and on support services for safety (including radiation protection), emergency preparedness and response, nuclear security, and the State system of accounting for and control of nuclear material, are also covered

  16. Governmental, Legal and Regulatory Framework for Safety. General Safety Requirements. Part 1 (Chinese Edition)

    International Nuclear Information System (INIS)

    2010-01-01

    The objective of this publication is to establish requirements in respect of the governmental, legal and regulatory framework for safety. It covers the essential aspects of the framework for establishing a regulatory body and taking other actions necessary to ensure the effective regulatory control of facilities and activities utilized for peaceful purposes. Other responsibilities and functions, such as liaison within the global safety regime and on support services for safety (including radiation protection), emergency preparedness and response, nuclear security, and the State system of accounting for and control of nuclear material, are also covered

  17. MODERN REQUIREMENTS TO THE GENERAL EDUCATIONAL ESTABLISHMENTS LEADERS IN FOREIGN COUNTRIES (FOREIGN EXPERIENCE

    Directory of Open Access Journals (Sweden)

    I. Malitskaya

    2010-08-01

    Full Text Available As a result of ICT integration into the school educational and administrative process, ICT competence is being included in normative educational documents and standards. In the article it has been considered modern requirements to the school leaders in foreign countries (The USA, Lithuania, European countries, it is presented the National educational technological standards (NETS•A. Performance indicators for administrators developed by International society for technology in education ISTE, which is used for development of their own standards in different foreign countries.

  18. An overview of fiber-to-the-premises (FTTP) product requirements and qualification programs

    Science.gov (United States)

    Gebizlioglu, Osman S.; Gallo, Ernest J.

    2006-04-01

    North American deployments of FTTP architectures have been rapidly increasing. While the FTTP market is being driven by major telecommunications service providers, equipment suppliers have been scrambling to bring products to market that will ensure them a piece of this high-stakes market. In this invited presentation/paper, we propose to examine the technical requirements that are needed to support the new FTTP network with a host of new products that have been in development. To enable service providers select the best new products for FTTP deployment, product selection needs to be based on the analysis and testing of new products for performance and reliability, Telcordia, in its traditional role of telecommunications standards development, has been publishing generic requirements (GR) documents that have been used by suppliers, service providers and the industry at large. Product qualification programs based on the established performance and reliability requirements/standards have been designed to evaluate products to determine if they can 1) withstand the rigors of the outside plant deployment environment and perform for extended periods of time, 2) be upgradeable, and 3) craft friendly. The outside plant is a tough environment to live in. A product must perform under the extreme conditions of cold down -40°C (-40°F) and hot up to 46°C (115°F) with high humidity of 95%, rain, snow, sleet, vibration due to traffic, lightning, heating due to solar loads, high winds, ice, sand storms, and products are even tested to demonstrate if they can continue to operate in an earthquake, a wild fire and a shotgun blast. All FTTP products are not only expected to perform, but they must meet stringent optical performance criteria of low insertion loss and reflectance / return loss at a broad range of wavelengths from 1310, 1490, 1550 and 1625 nm. While the upstream (from the customer to the CO) voice and data transmission is currently planned over 1310-nm wavelength, the

  19. Material properties requirements for LMFBR structural design: General considerations and data needs

    Energy Technology Data Exchange (ETDEWEB)

    Pugh, C E [Oak Ridge National Laboratory, Oak Ridge, TN (United States); Purdy, C M [U.S. Energy Research and Development Administration (United States)

    1977-07-01

    A statement is given of material properties information needed in connection with the structural design technology for liquid-metal fast breeder reactor (LMFBR) primary circuit components. Implementation of current analysis methods and criteria is considered with an emphasis on data and data correlations for performing elastic-plastic and creep analyses, for establishing allowable stress limits, and for computing creep-fatigue damage. Further development of the technology is discussed in relation to properties information. Emphasis is placed on improved constitutive equations for representing inelastic material behavior, on procedures for treating time-dependent fatigue, and on criteria for creep rupture. The properties are generally discussed without regard to specific alloys, since most categories of information are needed for each major structural material. Some sample experimental results are given for type 304 stainless steel and 2 1/4 Cr-1 Mo steel. (author)

  20. Material properties requirements for LMFBR structural design: general considerations and data needs

    International Nuclear Information System (INIS)

    Pugh, C.E.; Purdy, C.M.

    1977-01-01

    A statement is given of material properties information needed in connection with the structural design technology for liquid-metal fast breeder reactor (LMFBR) primary circuit components. Implementation of current analysis methods and criteria is considered with an emphasis on data and data correlations for performing elastic-plastic and creep analyses, for establishing allowable stress limits, and for computing creep-fatigue damage. Further development of the technology is discussed in relation to properties information. Emphasis is placed on improved constitutive equations for representing inelastic material behavior, on procedures for treating time-dependent fatigue, and on criteria for creep rupture. The properties are generally discussed without regard to specific alloys, since most categories of information are needed for each major structural material. Some sample experimental results are given for type 304 stainless steel and 2 1 / 4 Cr-1 Mo steel

  1. Relational coordination is associated with productivity in general practice: a survey and register based study

    DEFF Research Database (Denmark)

    Lundstrøm, Sanne Lykke; Edwards, Kasper; Reventlow, Susanne

    2014-01-01

    In this paper we investigate the association between relational coordination among the practice team in general practice and number of consultations performed in a general practice per staff, i.e. a proxy of productivity. We measured relational coordination using the Relational Coordination Survey...... and combined the results with register data. We found that relational coordination was statistically significant associated with number of consultation per staff per year. We later divided consultations in to three types: Face-to-face, Email and phone consultations. We found a statistically significant...... associating between relational coordination and with number of face-to-face consultation per staff per year....

  2. Definition of the generalized criterion of estimation of ecological purity of textile products

    International Nuclear Information System (INIS)

    Gintibidze, N.; Valishvili, T.

    2009-01-01

    One of actual problems is the estimation of hygienic and ecological properties of fabrics on the basis of the data on the properties of initial fiber. In the present article, the definition of generalized criterion of the estimation of ecological purity of textile products is discussed. The estimation is based on the International Standard EKO-TEX-100, regulating the contents of inorganic and organic compounds in textile production. The determination of all listed substances is made according to appropriate techniques for each parameter. The quantity of substances is determined and compared with norms. The judgement about ecological purity is made by separate parameters. There is no uniform parameter which could estimate the degree of ecological purity of textile products. For calculating the generalized criterion of estimation of ecological purity of textile products, it is offered to estimate each criterion by the points corresponding to each factor. The textile product is recognized as ecologically pure (environment friendly) if the total estimate is more than 1. (author)

  3. 76 FR 18645 - Third Party Testing for Certain Children's Products; Notice of Requirements for Accreditation of...

    Science.gov (United States)

    2011-04-05

    ... to the International Standards Organization (ISO)/International Electrotechnical Commission (IEC) Standard ISO/IEC 17025:2005, ``General Requirements for the Competence of Testing and Calibration... paint ban and 16 CFR part 1303, it must be accredited to ISO/IEC 17025- 2005 by an accreditation body...

  4. General concept of a gas engine for a hybrid vehicle, operating on methanol dissociation products

    International Nuclear Information System (INIS)

    Tartakovsky, L.; Aleinikov, Y.; Fainberg, V.; Garbar, A.; Gutman, M.; Hetsroni, G.; Schindler, Y.; Zvirin, Y.

    1998-01-01

    The paper presents a general concept of a hybrid propulsion system, based on an SI internal combustion engine fueled by methanol dissociation products (MDP). The proposed hybrid propulsion scheme is a series hybrid, which allows the engine to be operated in an on-off mode at constant optimal regime. The engine is fed by gaseous products of methanol dissociation (mainly hydrogen and carbon monoxide) emerging from an on-board catalytic reformer. The general scheme and base operation features of the propulsion system are described. The benefits that may be achieved by combining the well-known idea of on-board methanol dissociation with the hybrid vehicle concept are discussed. The proposed scheme is compared with those of systems operating on gasoline, liquid methanol, hydrogen and also with the multi-regime (not hybrid) engine fed by MDP

  5. A General and Intuitive Approach to Understand and Compare the Torque Production Capability of AC Machines

    DEFF Research Database (Denmark)

    Wang, Dong; Lu, Kaiyuan; Rasmussen, Peter Omand

    2014-01-01

    Electromagnetic torque analysis is one of the key issues in the analysis of electric machines. It plays an important role in machine design and control. The common method described in most of the textbooks is to calculate the torque in the machine variables and then transform them to the dq......-frame, through complicated mathematical manipulations. This is a more mathematical approach rather than explaining the physics behind torque production, which even brings a lot of difficulties to specialist. This paper introduces a general and intuitive approach to obtain the dq-frame torque equation of various...... AC machines. In this method, torque equation can be obtained based on the intuitive physical understanding of the mechanism behind torque production. It is then approved to be applicable for general case, including rotor saliency and various types of magnetomotive force sources. As an application...

  6. Generalized peritonitis requiring re-operation after leakage of omental patch repair of perforated peptic ulcer.

    Science.gov (United States)

    Maghsoudi, Hemmat; Ghaffari, Alireza

    2011-01-01

    Peptic ulcer perforations are a common emergency, but available literature is silent on the exact definition, incidence, management, and complications of peritonitis due to omental patch leakage. Retrospective data were collected on 422 patients who underwent omental patch repair of perforated peptic ulcer between March 20, 1999 and March 20, 2006. The definitive diagnosis of perforated peptic ulcer and omental patch leakage was obtained at surgery. Seventeen (4%) patients experienced generalized peritonitis due to omental patch leakage. Mean age was 60.6 years. Mortality rate was 29.4%, and the mean hospital stay was 23.6 days. Delay in surgical approach, shock on admission, and age were all significantly associated with increased mortality. Peritonitis due to omental patch leakage can result in significant morbidity and mortality. The most common causes of omental patch leakage and operative procedures were unknown and reinsertion of omentum, respectively. Factors such as shock on admission or delayed surgery, have significantly contributed to fatal outcomes and need careful attention.

  7. 39 CFR 3.9 - Establishment of rates and classes of competitive products of general applicability.

    Science.gov (United States)

    2010-07-01

    ... 39 Postal Service 1 2010-07-01 2010-07-01 false Establishment of rates and classes of competitive products of general applicability. 3.9 Section 3.9 Postal Service UNITED STATES POSTAL SERVICE THE BOARD OF... demonstrating compliance with the standards of 39 U.S.C. 3633(a). (b) Pursuant to § 6.6(f) of these bylaws, the...

  8. Metrology requirements for the serial production of ELT primary mirror segments

    Science.gov (United States)

    Rees, Paul C. T.; Gray, Caroline

    2015-08-01

    The manufacture of the next generation of large astronomical telescopes, the extremely large telescopes (ELT), requires the rapid manufacture of greater than 500 1.44m hexagonal segments for the primary mirror of each telescope. Both leading projects, the Thirty Meter Telescope (TMT) and the European Extremely Large Telescope (E-ELT), have set highly demanding technical requirements for each fabricated segment. These technical requirements, when combined with the anticipated construction schedule for each telescope, suggest that more than one optical fabricator will be involved in the delivery of the primary mirror segments in order to meet the project schedule. For one supplier, the technical specification is challenging and requires highly consistent control of metrology in close coordination with the polishing technologies used in order to optimize production rates. For production using multiple suppliers, however the supply chain is structured, consistent control of metrology along the supply chain will be required. This requires a broader pattern of independent verification than is the case of a single supplier. This paper outlines the metrology requirements for a single supplier throughout all stages of the fabrication process. We identify and outline those areas where metrology accuracy and duration have a significant impact on production efficiency. We use the challenging ESO E-ELT technical specification as an example of our treatment, including actual process data. We further develop this model for the case of a supply chain consisting of multiple suppliers. Here, we emphasize the need to control metrology throughout the supply chain in order to optimize net production efficiency.

  9. Entropy Production and Equilibrium Conditions of General-Covariant Spin Systems

    Directory of Open Access Journals (Sweden)

    Wolfgang Muschik

    2015-12-01

    Full Text Available In generalizing the special-relativistic one-component version of Eckart’s continuum thermodynamics to general-relativistic space-times with Riemannian or post-Riemannian geometry as presented by Schouten (Schouten, J.A. Ricci-Calculus, 1954 and Blagojevic (Blagojevic, M. Gauge Theories of Gravitation, 2013 we consider the entropy production and other thermodynamical quantities, such as the entropy flux and the Gibbs fundamental equation. We discuss equilibrium conditions in gravitational theories, which are based on such geometries. In particular, thermodynamic implications of the non-symmetry of the energy-momentum tensor and the related spin balance equations are investigated, also for the special case of general relativity.

  10. Track 8: health and radiological applications. Isotopes and radiation: general. 2. Radiation Pasteurization for Diverse Food Products

    International Nuclear Information System (INIS)

    Braby, L.A.; Whittaker, A.D.; McLellan, M.; Waltar, A.E.

    2001-01-01

    After a lengthy and controversial development period, radiation-pasteurized products that can be easily recognized by consumers are starting to make it to a few grocery store shelves. Of course, certain spices used in packaged products and a wide variety of nonfood products have been irradiated for many years. However, the involvement of radiation processing in these products has generally gone unrecognized by the consumers. More recently, the approval of irradiated poultry and red meat, which would bear a clear label indicating radiation treatment, has provided an opportunity to confirm the consumers' acceptance of irradiated products. The early indications are that consumers not only accept, but they actually prefer, the irradiated product when it is available. In spite of extensive efforts of antinuclear activists to convince the public that there are unknown but potentially serious hazards associated with radiation-processed food, along with some misleading reports in the news media suggesting that retailers had withdrawn irradiated products from their shelves, it appears that those retailers who received irradiated meat sold their complete inventory in short order. Further, they did so at substantial price premiums relative to equivalent un-irradiated products. Apparently, the combination of more than 40 yr of research showing no credible evidence of hazards produced by irradiation, augmented by greater public awareness of the risks of some food-borne pathogens, has convinced some consumers that use of radiation-processed products is in their personal best interest. Furthermore, the reluctance of many producers and retailers to introduce irradiated products for fear of adverse publicity is being countered by recognition that if an un-irradiated product is found to be responsible for a significant incidence of food-borne illness, their liability may be high because they did not use the 'best available technology for minimizing risk', namely, irradiation

  11. 15 CFR 714.3 - Advance declaration requirements for additionally planned production of Schedule 3 chemicals.

    Science.gov (United States)

    2010-01-01

    ... COMMERCE CHEMICAL WEAPONS CONVENTION REGULATIONS ACTIVITIES INVOLVING SCHEDULE 3 CHEMICALS § 714.3 Advance... 15 Commerce and Foreign Trade 2 2010-01-01 2010-01-01 false Advance declaration requirements for additionally planned production of Schedule 3 chemicals. 714.3 Section 714.3 Commerce and Foreign Trade...

  12. 40 CFR 152.15 - Pesticide products required to be registered.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 23 2010-07-01 2010-07-01 false Pesticide products required to be registered. 152.15 Section 152.15 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED... actual or constructive knowledge that the substance will be used, or is intended to be used, for a...

  13. Harvest operations for density management: planning requirements, production, costs, stand damage, and recommendations

    Science.gov (United States)

    Loren D. Kellogg; Stephen J. Pilkerton

    2013-01-01

    Since the early 1990s, several studies have been undertaken to determine the planning requirements, productivity, costs, and residual stand damage of harvest operations in thinning treatments designed to promote development of complex forest structure in order to enhance ecological functioning and biological diversity. Th ese studies include the Oregon State...

  14. 78 FR 41298 - Children's Products Containing Lead; Procedures and Requirements for Exclusions From Lead Limits...

    Science.gov (United States)

    2013-07-10

    ... on materials previously submitted in connection with a petition for exclusion under this section. In... 16 CFR 1500.90 to provide procedures and requirements for evaluating products or materials for... and comment rulemaking, section 553 of the APA provides an exception when the agency, for good cause...

  15. 21 CFR 111.255 - What is the requirement to establish a batch production record?

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 2 2010-04-01 2010-04-01 false What is the requirement to establish a batch production record? 111.255 Section 111.255 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) FOOD FOR HUMAN CONSUMPTION CURRENT GOOD MANUFACTURING PRACTICE IN...

  16. 40 CFR 112.9 - Spill Prevention, Control, and Countermeasure Plan Requirements for onshore oil production...

    Science.gov (United States)

    2010-07-01

    ... measures required under § 112.7(c)(1), except when draining uncontaminated rainwater. Prior to drainage... with legally approved methods. (2) Inspect at regularly scheduled intervals field drainage systems... prevention and containment procedures listed under this section. (b) Oil production facility drainage. (1) At...

  17. Irrigation requirements for seed production of five Lomatium species in a semiarid environment

    Science.gov (United States)

    Clinton C. Shock; Erik B. G. Feibert; Alicia Rivera; Lamont D. Saunders; Nancy Shaw; Francis F. Kilkenny

    2016-01-01

    Seeds of native plants are needed for rangeland restoration in the Intermountain West. Many of these plants are rarely cultivated and relatively little is known about the cultural practices required for their seed production. Irrigation trials were conducted for five perennial Lomatium species over multiple years. Lomatium species grown at the Oregon State University...

  18. Analysis of power and frequency control requirements in view of increased decentralized production and market liberalization

    International Nuclear Information System (INIS)

    Roffel, B.; Boer, W.W. de

    2003-01-01

    This paper presents a systematic approach of the analysis of the minimum control requirements that are imposed on power producing units in the Netherlands, especially in the case when decentralized production increases. Also some effects of the liberalization on the control behavior are analyzed. First an overview is given of the amount and type of power production in the Netherlands, followed by a review of the control requirements. Next models are described, including a simplified model for the UCTE power system. The model was tested against frequency and power measurements after failure of a 558 MW production unit in the Netherlands. Agreement between measurements and model predictions proved to be good. The model was subsequently used to analyze the primary and secondary control requirements and the impact of an increase in decentralized power production on the fault restoration capabilities of the power system. Since the latter production units are not actively participating in primary and secondary control, fault restoration takes longer and becomes unacceptable when only 35% of the power producing units participate in secondary control. Finally, the model was used to study the impact of deregulation, especially the effect of 'block scheduling', on additional control actions of the secondary control. (Author)

  19. An overview of technical requirements on durable concrete production for near surface disposal facilities for radioactive wastes

    International Nuclear Information System (INIS)

    Tolentino, Evandro; Tello, Cledola Cassia Oliveira de

    2013-01-01

    Radioactive waste can be generated by a wide range of activities varying from activities in hospitals to nuclear power plants, to mines and mineral processing facilities. General public have devoted nowadays considerable attention to the subject of radioactive waste management due to heightened awareness of environmental protection. The preferred strategy for the management of all radioactive waste is to contain it and to isolate it from the accessible biosphere. The Federal Government of Brazil has announced the construction for the year of 2014 and operation for the year of 2016 of a near surface disposal facility for low and intermediate level radioactive waste. The objective of this paper is to provide an overview of technical requirements related to production of durable concrete to be used in near surface disposal facilities for radioactive waste concrete structures. These requirements have been considered by researchers dealing with ongoing designing effort of the Brazilian near surface disposal facility. (author)

  20. Prospects on hydrogen production for a generalized domestic, industrial and automotive, usage

    Science.gov (United States)

    Dini, D.

    Assuming the availability of advanced nuclear and solar systems as prime energy sources for electrolytic production of hydrogen, an assessment is made of high pressure electrolytic gasification, liquefaction and storage work requirements. Also, a pipeline network and associated equipment for the delivery and storage of hydrogen are considered in the context of a future replacement of all fossil fuels by hydrogen. Attention is given to space-based systems and terrestrial photovoltaics.

  1. Requirement analysis for the one-stop logistics management of fresh agricultural products

    Science.gov (United States)

    Li, Jun; Gao, Hongmei; Liu, Yuchuan

    2017-08-01

    Issues and concerns for food safety, agro-processing, and the environmental and ecological impact of food production have been attracted many research interests. Traceability and logistics management of fresh agricultural products is faced with the technological challenges including food product label and identification, activity/process characterization, information systems for the supply chain, i.e., from farm to table. Application of one-stop logistics service focuses on the whole supply chain process integration for fresh agricultural products is studied. A collaborative research project for the supply and logistics of fresh agricultural products in Tianjin was performed. Requirement analysis for the one-stop logistics management information system is studied. The model-driven business transformation, an approach uses formal models to explicitly define the structure and behavior of a business, is applied for the review and analysis process. Specific requirements for the logistic management solutions are proposed. Development of this research is crucial for the solution of one-stop logistics management information system integration platform for fresh agricultural products.

  2. Global impacts of U.S. bioenergy production and policy: A general equilibrium perspective

    Science.gov (United States)

    Evans, Samuel Garner

    The conversion of biomass to energy represents a promising pathway forward in efforts to reduce fossil fuel use in the transportation and electricity sectors. In addition to potential benefits, such as greenhouse gas reductions and increased energy security, bioenergy production also presents a unique set of challenges. These challenges include tradeoffs between food and fuel production, distortions in energy markets, and terrestrial emissions associated with changing land-use patterns. Each of these challenges arises from market-mediated responses to bioenergy production, and are therefore largely economic in nature. This dissertation directly addresses these opportunities and challenges by evaluating the economic impacts of U.S. bioenergy production and policy, focusing on both existing and future biomass-to-energy pathways. The analysis approaches the issue from a global, economy-wide perspective, reflecting two important facts. First, that large-scale bioenergy production connects multiple sectors of the economy due to the use of agricultural land resources for biomass production, and competition with fossil fuels in energy markets. Second, markets for both agricultural and energy commodities are highly integrated globally, causing domestic policies to have international effects. The reader can think of this work as being comprised of three parts. Part I provides context through an extensive review of the literature on the market-mediated effects of conventional biofuel production (Chapter 2) and develops a general equilibrium modeling framework for assessing the extent to which these phenomenon present a challenge for future bioenergy pathways (Chapter 3). Part II (Chapter 4) explores the economic impacts of the lignocellulosic biofuel production targets set in the U.S. Renewable Fuel Standard on global agricultural and energy commodity markets. Part III (Chapter 5) extends the analysis to consider potential inefficiencies associated with policy

  3. Progesterone production requires activation of caspase-3 in preovulatory granulosa cells in a serum starvation model.

    Science.gov (United States)

    An, Li-Sha; Yuan, Xiao-Hua; Hu, Ying; Shi, Zi-Yun; Liu, Xiao-Qin; Qin, Li; Wu, Gui-Qing; Han, Wei; Wang, Ya-Qin; Ma, Xu

    2012-11-01

    Granulosa cells proliferate, differentiate, and undergo apoptosis throughout follicular development. Previous studies have demonstrated that stimulation of progesterone production is accompanied by caspase-3 activation. Moreover, we previously reported that arsenic enhanced caspase-3 activity coupled with progesterone production. Inhibition of caspase-3 activity can significantly inhibit progesterone production induced by arsenic or follicle-stimulating hormone (FSH). Here, we report that serum starvation induces caspase-3 activation coupled with augmentation of progesterone production. Serum starvation also increased the levels of cytochrome P450 cholesterol side chain cleavage enzyme (P450scc) and steroidogenic acute regulatory (StAR) protein, both of which may contribute to progesterone synthesis in preovulatory granulosa cells. Inhibition of caspase-3 activity resulted in a decrease in progesterone production. Deactivation of caspase-3 activity by caspase-3 specific inhibitor also resulted in decreases in P450scc and StAR expression, which may partly contribute to the observed decrease in progesterone production. Our study demonstrates for the first time that progesterone production in preovulatory granulosa cells is required for caspase-3 activation in a serum starvation model. Inhibition of caspase-3 activity can result in decreased expression of the steroidogenic proteins P450scc and StAR. Our work provides further details on the relationship between caspase-3 activation and steroidogenesis and indicates that caspase-3 plays a critical role in progesterone production by granulosa cells. Copyright © 2012 Elsevier Inc. All rights reserved.

  4. [Regulatory requirements regarding cell-based medicinal products for human and veterinary use - a comparison].

    Science.gov (United States)

    Kuhlmann-Gottke, Johanna; Duchow, Karin

    2015-11-01

    At present, there is no separate regulatory framework for cell-based medicinal products (CBMP) for veterinary use at the European or German level. Current European and national regulations exclusively apply to the corresponding medicinal products for human use. An increasing number of requests for the regulatory classification of CBMP for veterinary use, such as allogeneic stem cell preparations and dendritic cell-based autologous tumour vaccines, and a rise in scientific advice for companies developing these products, illustrate the need for adequate legislation. Currently, advice is given and decisions are made on a case-by-case basis regarding the regulatory classification and authorisation requirements.Since some of the CBMP - in particular in the area of stem-cell products - are developed in parallel for human and veterinary use, there is an urgent need to create specific legal definitions, regulations, and guidelines for these complex innovative products in the veterinary sector as well. Otherwise, there is a risk that that the current legal grey area regarding veterinary medicinal products will impede therapeutic innovations in the long run. A harmonised EU-wide approach is desirable. Currently the European legislation on veterinary medicinal products is under revision. In this context, veterinary therapeutics based on allogeneic cells and tissues will be defined and regulated. Certainly, the legal framework does not have to be as comprehensive as for human CBMP; a leaner solution is conceivable, similar to the special provisions for advanced-therapy medicinal products laid down in the German Medicines Act.

  5. Microalgae Oil Production: A Downstream Approach to Energy Requirements for the Minamisoma Pilot Plant

    Directory of Open Access Journals (Sweden)

    Dhani S. Wibawa

    2018-02-01

    Full Text Available This study investigates the potential of microalgae oil production as an alternative renewable energy source, in a pilot project located at Minamisoma City in the Fukushima Prefecture of Japan. The algal communities used in this research were the locally mixed species, which were mainly composed of Desmodesmus collected from the Minamisoma pilot project. The microalgae oil-production processes in Minamisoma consisted of three stages: cultivation, dewatering, and extraction. The estimated theoretical input-energy requirement for extracting oil was 137.25 MJ to process 50 m3 of microalgae, which was divided into cultivation 15.40 MJ, centrifuge 13.39 MJ, drum filter 14.17 MJ, and hydrothermal liquefaction (HTL 94.29 MJ. The energy profit ratio (EPR was 1.41. The total energy requirement was highest in the HTL process (68% followed by cultivation (11% and the drum filter (10%. The EPR value increased along with the yield in the cultivation process. Using HTL, the microalgae biomass could be converted to bio-crude oil to increase the oil yield in the extraction process. Therefore, in the long run, the HTL process could help lower production costs, due to the lack of chemical additions, for extracting oil in the downstream estimation of the energy requirements for microalgae oil production.

  6. The Use of Cognitive Maps for Requirements Elicitation in Product Development

    Directory of Open Access Journals (Sweden)

    Raquel Dias

    2016-04-01

    Full Text Available This article approaches Engineering Requirements concepts and proposes the use of cognitive maps as support to the problem identification of the stakeholders during the requirements elicitation process. It presents a case study of the aerospace cluster of São José dos Campos, State of São Paulo. The cognitive map technique was developed to represent the views of the individuals, generating cognitive maps, which, in an aggregated way, express graphically the collective vision to support the decision-making process. Applied to Engineering Requirements, it has revealed the potential to promote the convergence of different points of view on the actual stakeholders’ needs in innovative fashion. This technique has demonstrated effectiveness when approaching the stated requirements early in the development process implemented throughout the life cycle of the system/product.

  7. Water Footprint and Land Requirement of Solar Thermochemical Jet-Fuel Production.

    Science.gov (United States)

    Falter, Christoph; Pitz-Paal, Robert

    2017-11-07

    The production of alternative fuels via the solar thermochemical pathway has the potential to provide supply security and to significantly reduce greenhouse gas emissions. H 2 O and CO 2 are converted to liquid hydrocarbon fuels using concentrated solar energy mediated by redox reactions of a metal oxide. Because attractive production locations are in arid regions, the water footprint and the land requirement of this fuel production pathway are analyzed. The water footprint consists of 7.4 liters per liter of jet fuel of direct demand on-site and 42.4 liters per liter of jet fuel of indirect demand, where the dominant contributions are the mining of the rare earth oxide ceria, the manufacturing of the solar concentration infrastructure, and the cleaning of the mirrors. The area-specific productivity is found to be 33 362 liters per hectare per year of jet fuel equivalents, where the land coverage is mainly due to the concentration of solar energy for heat and electricity. The water footprint and the land requirement of the solar thermochemical fuel pathway are larger than the best power-to-liquid pathways but an order of magnitude lower than the best biomass-to-liquid pathways. For the production of solar thermochemical fuels arid regions are best-suited, and for biofuels regions of a moderate and humid climate.

  8. Construction products performances and basic requirements for fire safety of facades in energy rehabilitation of buildings

    Directory of Open Access Journals (Sweden)

    Laban Mirjana Đ.

    2015-01-01

    Full Text Available Construction product means any product or kit which is produced and placed on the market for incorporation in a permanent manner in construction works, or parts thereof, and the performance of which has an effect on the performance of the construction works with respect to the basic requirements for construction works. Safety in case of fire and Energy economy and heat retention represent two among seven basic requirements which building has to meet according to contemporary technical rules on planning and construction. Performances of external walls building materials (particularly reaction to fire could significantly affect to fire spread on the façade and other building parts. Therefore, façade shaping and materialization in building renewal process, has to meet the fire safety requirement, as well as the energy requirement. Brief survey of fire protection regulations development in Serbia is presented in the paper. Preventive measures for fire risk reduction in building façade energy renewal are proposed according to contemporary fire safety requirements.

  9. Modulated molecular beam mass spectrometry: A generalized expression for the ''reaction product vector'' for linear systems

    International Nuclear Information System (INIS)

    Chang, H.; Weinberg, W.H.

    1977-01-01

    A generalized expression is developed that relates the ''reaction product vector'', epsilon exp(-iphi), to the kinetic parameters of a linear system. The formalism is appropriate for the analysis of modulated molecular beam mass spectrometry data and facilitates the correlation of experimental results to (proposed) linear models. A study of stability criteria appropriate for modulated molecular beam mass spectrometry experiments is also presented. This investigation has led to interesting inherent limitations which have not heretofore been emphasized, as well as a delineation of the conditions under which stable chemical oscillations may occur in the reacting system

  10. Exclusive neutrino production of a charmed vector meson and transversity gluon generalized parton distributions

    Science.gov (United States)

    Pire, B.; Szymanowski, L.

    2017-12-01

    We calculate at the leading order in αs the QCD amplitude for exclusive neutrino production of a D* or Ds* charmed vector meson on a nucleon. We work in the framework of the collinear QCD approach where generalized parton distributions (GPDs) factorize from perturbatively calculable coefficient functions. We include O (mc) terms in the coefficient functions and the O (mD) term in the definition of heavy meson distribution amplitudes. The show that the analysis of the angular distribution of the decay D(s) *→D(s )π allows us to access the transversity gluon GPDs.

  11. General scheme of research reactor mainly for production of fission 99Mo

    International Nuclear Information System (INIS)

    Shen Feng; Liu Xingmin; Wu Xiaochun; Sun Zheng; Guo Chunqiu; Yi Dayong

    2012-01-01

    On the basis of the analysis for current circumstance and development tendency of research reactor mainly for 99 Mo production in the world, the design idea of this sort of research reactor was proposed. By the optimization and basic design, the general design parameters of the reactor were analyzed and testified. The evaluation of output activities of 99 Mo and the analysis of economics were conducted on the basically assumption. It is argued that the economics of this reactor is improved dramatically while the safety is ensured by the analysis. (authors)

  12. Modeling requirements for full-scope reactor simulators of fission-product transport during severe accidents

    International Nuclear Information System (INIS)

    Ellison, P.G.; Monson, P.R.; Mitchell, H.A.

    1990-01-01

    This paper describes in the needs and requirements to properly and efficiently model fission product transport on full scope reactor simulators. Current LWR simulators can be easily adapted to model severe accident phenomena and the transport of radionuclides. Once adapted these simulators can be used as a training tool during operator training exercises for training on severe accident guidelines, for training on containment venting procedures, or as training tool during site wide emergency training exercises

  13. 40 CFR 158.2030 - Biochemical pesticides product chemistry data requirements table.

    Science.gov (United States)

    2010-07-01

    ....7100 Viscosity CR MP EP 12 830.7200 Melting point/melting range CR TGAI TGAI 8, 13 830.7220 Boiling point/boiling range CR TGAI TGAI 8, 14 830.7300 Density/relative density/bulk density R TGAI and MP TGAI.... (2) Definitions in § 158.300 apply to data requirements in this section. (b) Use patterns. Product...

  14. Trading Land: A Review of Approaches to Accounting for Upstream Land Requirements of Traded Products.

    Science.gov (United States)

    Schaffartzik, Anke; Haberl, Helmut; Kastner, Thomas; Wiedenhofer, Dominik; Eisenmenger, Nina; Erb, Karl-Heinz

    2015-10-01

    Land use is recognized as a pervasive driver of environmental impacts, including climate change and biodiversity loss. Global trade leads to "telecoupling" between the land use of production and the consumption of biomass-based goods and services. Telecoupling is captured by accounts of the upstream land requirements associated with traded products, also commonly referred to as land footprints. These accounts face challenges in two main areas: (1) the allocation of land to products traded and consumed and (2) the metrics to account for differences in land quality and land-use intensity. For two main families of accounting approaches (biophysical, factor-based and environmentally extended input-output analysis), this review discusses conceptual differences and compares results for land footprints. Biophysical approaches are able to capture a large number of products and different land uses, but suffer from a truncation problem. Economic approaches solve the truncation problem, but are hampered by the limited disaggregation of sectors and products. In light of the conceptual differences, the overall similarity of results generated by both types of approaches is remarkable. Diametrically opposed results for some of the world's largest producers and consumers of biomass-based products, however, make interpretation difficult. This review aims to provide clarity on some of the underlying conceptual issues of accounting for land footprints.

  15. Machinery and labour force requirements for forest chip production in Finland in 2020

    Energy Technology Data Exchange (ETDEWEB)

    Kaerhae, K.; Strandsroem, M. (Metsaeteho Oy, Helsinki (Finland)), Email: kalle.karha@metsateho.fi, Email: markus.strandstrom@metsateho.fi; Lahtinen, P.; Elo, J. (Poeyry Energy Oy, Espoo (Finland)), Email: perttu.lahtinen@poyry.com, Email: juha.elo@poyry.com

    2009-07-01

    The research carried out by Metsaeteho Oy and Poeyry Energy Oy estimated how much machinery and labour would be needed for large-scale forest chip production if the use of forest chips increases extensively in Finland during the coming decade. If the production and consumption of forest chips are 25 to 30 TWh in Finland 2020, then 1,900 to 2,200 machinery units, i.e. machines and trucks, would be needed. This would mean total investments in production machinery of 530 to 630 million euro (VAT 0 %). The labour demand would be 3,400 to 4,000 machine operators and drivers, and 4,200 to 5,100 labour years including indirect labour. Respectively, if the production and consumption of forest chips is 15 to 20 TWh in Finland in 2020, then the production machinery requirement would be 1,100 to 1,500 machines and trucks. The total machinery investment cost would be 320 to 420 million euro (VAT 0 %) and the calculated labour demand 2,000 to 2,700 machine operators and drivers (2,500 to 3,400 labour years). The results of the study indicated that forest chip production resources will be a major bottleneck in reaching the consumption target of 12 million m3, i.e. around 24 TWh of forest chips in Finland by 2020. (orig.)

  16. Requirement Analysis for the Collaborative Supply and Logistics Management of Fresh Agricultural Products

    Directory of Open Access Journals (Sweden)

    Li Jun

    2017-01-01

    Full Text Available Issues and concerns for food safety, agro-processing, and the environmental and ecological impact of food production have been attracted many research interests. Traceability and logistics management of fresh agricultural products is faced with the technological challenges including food product label and identification, activity/process characterization, information systems for the supply chain, i.e., from farm to table. Application of information technologies for food processing and logistics industry in the fields of smart packaging and materials, automation and control technology, standards and their application scenarios, and production management principles were wildly studied. A collaborative research project for the supply and logistics of fresh agricultural products in Tianjin was performed. System analysis for the logistics management information system is studied. The model-driven business transformation, an approach uses formal models to explicitly define the structure and behavior of a business, is applied for the review and analysis process. Requirements for the logistic management solutions are proposed. Development of this research is crucial for the solution integration of supply and logistic management information system for fresh agricultural products.

  17. Thematic strategy on sustainable use of plant protection products. Prospects and requirements for transferring proposals for plant protection products to biocides

    Energy Technology Data Exchange (ETDEWEB)

    Gartiser, Stefan [Hydrotox GmbH, Freiburg im Breisgau (Germany); Lueskow, Heike [Institut fuer Oekologie und Politik GmbH (OEKOPOL), Hamburg (Germany); Gross, Rita [Oeko-Institut e.V. - Institut fuer Angewandte Oekologie e.V., Freiburg im Breisgau (Germany)

    2012-03-15

    The sustainable use of pesticides pursues, independent of the authorisation of single products, the aim to minimise existing environmental risks of pesticide use and therefore contribute to the reduction of its impact on the environmental protection goals. The Thematic Strategy (TS) and the Framework Directive 2009/128/EC (FWD) on sustainable use of pesticides have so far only been implemented for plant protection products (PPP). For biocides there exists no harmonised approach. Within the project the possibilities and requirements for transferring measures of the FWD to the biocide area have been analysed, with specific focus on wood preservatives, insecticides, and antifouling products. Several biocidal active substances are found in the outlets of sewage treatment plants and in surface water, but an inventory of the present environmental impact as well as reliable data on biocide consumption and use patterns, which could be used to identify key action areas, are generally missing. These data are urgently needed for the development of suitable indicators and the definition of the objectives. Sustainable use of biocides addresses the three issues; social, environmental and economic impact at which the ecological background assigns the borderline and beam barrier of the economic and social development. A systematic analysis of the instruments for improving sustainable use of pesticides described in TS and FWD indicated that many issues can be transferred to the biocide area. This concerns e.g. education and training, requirements for sales, the establishment of awareness programmes, control of the machinery for biocide application, the development of best practice standards based on integrated pest management principles, and the collection of statistics on biocide consumption. Some biocide specific characteristics need to be considered: E.g. unlike PPP, the intended use of some biocides is to be directly applied in water bodies or indoors. Furthermore for some

  18. Design Of Measurements For Evaluating Readiness Of Technoware Components To Meet The Required Standard Of Products

    Science.gov (United States)

    Fauzi, Ilham; Muharram Hasby, Fariz; Irianto, Dradjad

    2018-03-01

    Although government is able to make mandatory standards that must be obeyed by the industry, the respective industries themselves often have difficulties to fulfil the requirements described in those standards. This is especially true in many small and medium sized enterprises that lack the required capital to invest in standard-compliant equipment and machineries. This study aims to develop a set of measurement tools for evaluating the level of readiness of production technology with respect to the requirements of a product standard based on the quality function deployment (QFD) method. By combining the QFD methodology, UNESCAP Technometric model [9] and Analytic Hierarchy Process (AHP), this model is used to measure a firm’s capability to fulfill government standard in the toy making industry. Expert opinions from both the governmental officers responsible for setting and implementing standards and the industry practitioners responsible for managing manufacturing processes are collected and processed to find out the technological capabilities that should be improved by the firm to fulfill the existing standard. This study showed that the proposed model can be used successfully to measure the gap between the requirements of the standard and the readiness of technoware technological component in a particular firm.

  19. Single Higgs-boson production through γγ scattering within the general 2HDM

    International Nuclear Information System (INIS)

    Bernal, Nicolas; Lopez-Val, David; Sola, Joan

    2009-01-01

    The production of a single neutral Higgs boson h through (loop-induced) γγ collisions is explored in the context of the linear colliders within the general Two-Higgs-Doublet Model (2HDM). Two different mechanisms are analyzed: on the one hand, the scattering γγ→h of two real photons in a γγ collider; on the other, the more traditional mechanism of virtual photon fusion, e + e - →e + e - γ*γ*→e + e - +h. Owing to the peculiar properties of the Higgs boson self-interactions within the general 2HDM, we find that the overall production rates can be boosted up significantly, provided the charged Higgs mass is not too heavy. For example, if M H ± ≥100 GeV and, in addition, M h 0 falls in the ballpark of the LEP bound on the SM Higgs mass up to a few hundred GeV, the cross-sections may typically render γγ→h >∼0.1-1 pb and σ(e + e - →e + e - h 0 )≤0.01 pb - in both cases well above the SM prediction. Although for M H ± >300 GeV the rates become virtually insensitive to the Higgs boson self-couplings, a significant tail of non-SM effects produced by the combined contribution of the Yukawa couplings and gauge bosons could still reveal a smoking gun.

  20. Routine inspection effort required for verification of a nuclear material production cutoff convention

    International Nuclear Information System (INIS)

    Dougherty, D.; Fainberg, A.; Sanborn, J.; Allentuck, J.; Sun, C.

    1996-11-01

    On 27 September 1993, President Clinton proposed open-quotes... a multilateral convention prohibiting the production of highly enriched uranium or plutonium for nuclear explosives purposes or outside of international safeguards.close quotes The UN General Assembly subsequently adopted a resolution recommending negotiation of a non-discriminatory, multilateral, and internationally and effectively verifiable treaty (hereinafter referred to as open-quotes the Cutoff Conventionclose quotes) banning the production of fissile material for nuclear weapons. The matter is now on the agenda of the Conference on Disarmament, although not yet under negotiation. This accord would, in effect, place all fissile material (defined as highly enriched uranium and plutonium) produced after entry into force (EIF) of the accord under international safeguards. open-quotes Productionclose quotes would mean separation of the material in question from radioactive fission products, as in spent fuel reprocessing, or enrichment of uranium above the 20% level, which defines highly enriched uranium (HEU). Facilities where such production could occur would be safeguarded to verify that either such production is not occurring or that all material produced at these facilities is maintained under safeguards

  1. 9 CFR 590.411 - Requirement of formulas and approval of labels for use in official egg products plants.

    Science.gov (United States)

    2010-01-01

    ... composition) is added to a liquid or frozen egg product or to an ingredient of such products (in excess of the... bulk packaged product. Nutrition labeling is required when nutrients, such as proteins, vitamins, and... consumers in such bulk form or containers. (2) Products containing an added vitamin, mineral, or protein, or...

  2. 21 CFR 111.55 - What are the requirements to implement a production and process control system?

    Science.gov (United States)

    2010-04-01

    ... production and process control system? 111.55 Section 111.55 Food and Drugs FOOD AND DRUG ADMINISTRATION... to Establish a Production and Process Control System § 111.55 What are the requirements to implement a production and process control system? You must implement a system of production and process...

  3. 9 CFR 590.900 - Requirements for importation of egg products or restricted eggs into the United States.

    Science.gov (United States)

    2010-01-01

    ... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false Requirements for importation of egg products or restricted eggs into the United States. 590.900 Section 590.900 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE EGG PRODUCTS INSPECTION INSPECTION OF...

  4. Should excessive worry be required for a diagnosis of generalized anxiety disorder? Results from the US National Comorbidity Survey Replication.

    Science.gov (United States)

    Ruscio, Ayelet Meron; Lane, Michael; Roy-Byrne, Peter; Stang, Paul E; Stein, Dan J; Wittchen, Hans-Ulrich; Kessler, Ronald C

    2005-12-01

    Excessive worry is required by DSM-IV, but not ICD-10, for a diagnosis of generalized anxiety disorder (GAD). No large-scale epidemiological study has ever examined the implications of this requirement for estimates of prevalence, severity, or correlates of GAD. Data were analyzed from the US National Comorbidity Survey Replication, a nationally representative, face-to-face survey of adults in the USA household population that was fielded in 2001-2003. DSM-IV GAD was assessed with Version 3.0 of the WHO Composite International Diagnostic Interview. Non-excessive worriers meeting all other DSM-IV criteria for GAD were compared with respondents who met full GAD criteria as well as with other survey respondents to consider the implications of removing the excessiveness requirement. The estimated lifetime prevalence of GAD increases by approximately 40% when the excessiveness requirement is removed. Excessive GAD begins earlier in life, has a more chronic course, and is associated with greater symptom severity and psychiatric co-morbidity than non-excessive GAD. However, non-excessive cases nonetheless evidence substantial persistence and impairment of GAD, high rates of treatment-seeking, and significantly elevated co-morbidity compared with respondents without GAD. Non-excessive cases also have sociodemographic characteristics and familial aggregation of GAD comparable to excessive cases. Individuals who meet all criteria for GAD other than excessiveness have a somewhat milder presentation than those with excessive worry, yet resemble excessive worriers in a number of important ways. These findings challenge the validity of the excessiveness requirement and highlight the need for further research into the optimal definition of GAD.

  5. A generalized business cycle model with delays in gross product and capital stock

    International Nuclear Information System (INIS)

    Hattaf, Khalid; Riad, Driss; Yousfi, Noura

    2017-01-01

    Highlights: • A generalized business cycle model is proposed and rigorously analyzed. • Well-posedness of the model and local stability of the economic equilibrium are investigated. • Direction of the Hopf bifurcation and stability of the bifurcating periodic solutions are determined. • A special case and some numerical simulations are presented. - Abstract: In this work, we propose a delayed business cycle model with general investment function. The time delays are introduced into gross product and capital stock, respectively. We first prove that the model is mathematically and economically well posed. In addition, the stability of the economic equilibrium and the existence of Hopf bifurcation are investigated. Our main results show that both time delays can cause the macro-economic system to fluctuate and the economic equilibrium to lose or gain its stability. Moreover, the direction of the Hopf bifurcation and the stability of the bifurcating periodic solutions are determined by means of the normal form method and center manifold theory. Furthermore, the models and results presented in many previous studies are improved and generalized.

  6. Increased ATP generation in the host cell is required for efficient vaccinia virus production

    Directory of Open Access Journals (Sweden)

    Hsu Che-Fang

    2009-09-01

    Full Text Available Abstract To search for cellular genes up-regulated by vaccinia virus (VV infection, differential display-reverse transcription-polymerase chain reaction (ddRT-PCR assays were used to examine the expression of mRNAs from mock-infected and VV-infected HeLa cells. Two mitochondrial genes for proteins that are part of the electron transport chain that generates ATP, ND4 and CO II, were up-regulated after VV infection. Up-regulation of ND4 level by VV infection was confirmed by Western blotting analysis. Up-regulation of ND4 was reduced by the MAPK inhibitor, apigenin, which has been demonstrated elsewhere to inhibit VV replication. The induction of ND4 expression occurred after viral DNA replication since ara C, an inhibitor of poxviral DNA replication, could block this induction. ATP production was increased in the host cells after VV infection. Moreover, 4.5 μM oligomycin, an inhibitor of ATP production, reduced the ATP level 13 hr after virus infection to that of mock-infected cells and inhibited viral protein expression and virus production, suggesting that increased ATP production is required for efficient VV production. Our results further suggest that induction of ND4 expression is through a Bcl-2 independent pathway.

  7. Regulatory requirements for clinical trial and marketing authorisation application for cell-based medicinal products.

    Science.gov (United States)

    Salmikangas, P; Flory, E; Reinhardt, J; Hinz, T; Maciulaitis, R

    2010-01-01

    The new era of regenerative medicine has led to rapid development of new innovative therapies especially for diseases and tissue/organ defects for which traditional therapies and medicinal products have not provided satisfactory outcome. Although the clinical use and developments of cell-based medicinal products (CBMPs) could be witnessed already for a decade, robust scientific and regulatory provisions for these products have only recently been enacted. The new Regulation for Advanced Therapies (EC) 1394/2007 together with the revised Annex I, Part IV of Directive 2001/83/EC provides the new legal framework for CBMPs. The wide variety of cell-based products and the foreseen limitations (small sample sizes, short shelf life) vs. particular risks (microbiological purity, variability, immunogenicity, tumourigenicity) associated with CBMPs have called for a flexible, case-by-case regulatory approach for these products. Consequently, a risk-based approach has been developed to allow definition of the amount of scientific data needed for a Marketing Authorisation Application (MAA) of each CBMP. The article provides further insight into the initial risk evaluation, as well as to the quality, non-clinical, and clinical requirements of CBMPs. Special somatic cell therapies designed for active immunotherapy are also addressed.

  8. General analysis of the intermediate vector boson production in hadron collisions

    International Nuclear Information System (INIS)

    Rekalo, M.P.

    1981-01-01

    Polarization states of intermediate vector W(Z) bosons produced in inclusive hadron-hadron collisions, a 1 +a 2 →W(Z)+X, where a 1 a 2 are some nonpolarized hadrons, X is a nondetected particle assembly are studied in general. Since spatial parity in these processes is not preserved, polarized W(Z) boson production must be determined by 9 real structural functions, 4 of which characterize the effects of invariance violation in relation to spatial reflections. Three structural functions (P-odd) for pole W(Z) production mechanisms in the quantum chromodynamics should exactly equal zero (with regard to the gluon errors). The relation of the W(Z) matrix elements with the structural functions in different coordinate systems used while discussing the angular distributions of W(Z) boson decay products is established. Decription of the W(Z) polarization properties is analyzed in terms of the 4-vector of spin and tenzor of quadrupole polarization [ru

  9. Improvement of uranium production efficiency to meet China's nuclear power requirements

    International Nuclear Information System (INIS)

    Zhang, R.

    1997-01-01

    Recently China put the Qinshan Nuclear Power Plant, with an installed capacity of 300 MW, in the province of Zhejiang and the Daya Bay Nuclear Power Plant, with a total installed capacity of 2 x 900 MW, in commercial operation. China plans a rapid growth in nuclear power from 1995 to 2010. China's uranium production will therefore also enter a new period with nuclear power increasing. In order to meet the demand of nuclear power for uranium special attention has been paid to both technical progress improvement using management with the aim of reducing the cost of uranium production. The application of the trackless mining technique has enhanced the uranium mining productivity significantly. China has produced a radiometric sorter, model 5421-2 for pre-concentrating uranium run-of-mine ore. This effectively increases the uranium content in mill feed and decreases the operating cost of hydrometallurgical treatment. The in situ leach technique after blasting is applied underground in the Lantian Mine, in addition to the surface heap leaching, and has obtained a perfect result. The concentrated acid-curing, and ferric sulphate trickle leaching process, will soon be used in commercial operation for treating uranium ore grading -5 to -7 mm in size. The annual production capability of the Yining Mine will be extended to 100 tonnes U using improving in situ leaching technology. For the purpose of improving the uranium production efficiency much work has been done optimizing the distribution of production centres. China plans to expand its uranium production to meet the uranium requirements of the developing nuclear power plants. (author). 4 tabs

  10. Innovation in Agriculture - a Way for Romanian Farmers to Adjust Production to Market Requirements

    Directory of Open Access Journals (Sweden)

    Manuela Dora Orboi

    2017-11-01

    produced products, to adapt production to market requirements, have better access to inputs, equipment, credit and marketing, to optimize their production costs, create short supply chains and handle with various market challenges.

  11. Composition and production rate of pharmaceutical and chemical waste from Xanthi General Hospital in Greece

    International Nuclear Information System (INIS)

    Voudrias, Evangelos; Goudakou, Lambrini; Kermenidou, Marianthi; Softa, Aikaterini

    2012-01-01

    Highlights: ► We studied pharmaceutical and chemical waste production in a Greek hospital. ► Pharmaceutical waste comprised 3.9% w/w of total hazardous medical waste. ► Unit production rate for total pharmaceutical waste was 12.4 ± 3.90 g/patient/d. ► Chemical waste comprised 1.8% w/w of total hazardous medical waste. ► Unit production rate for total chemical waste was 5.8 ± 2.2 g/patient/d. - Abstract: The objective of this work was to determine the composition and production rates of pharmaceutical and chemical waste produced by Xanthi General Hospital in Greece (XGH). This information is important to design and cost management systems for pharmaceutical and chemical waste, for safety and health considerations and for assessing environmental impact. A total of 233 kg pharmaceutical and 110 kg chemical waste was collected, manually separated and weighed over a period of five working weeks. The total production of pharmaceutical waste comprised 3.9% w/w of the total hazardous medical waste produced by the hospital. Total pharmaceutical waste was classified in three categories, vial waste comprising 51.1%, syringe waste with 11.4% and intravenous therapy (IV) waste with 37.5% w/w of the total. Vial pharmaceutical waste only was further classified in six major categories: antibiotics, digestive system drugs, analgesics, hormones, circulatory system drugs and “other”. Production data below are presented as average (standard deviation in parenthesis). The unit production rates for total pharmaceutical waste for the hospital were 12.4 (3.90) g/patient/d and 24.6 (7.48) g/bed/d. The respective unit production rates were: (1) for vial waste 6.4 (1.6) g/patient/d and 13 (2.6) g/bed/d, (2) for syringe waste 1.4 (0.4) g/patient/d and 2.8 (0.8) g/bed/d and (3) for IV waste 4.6 (3.0) g/patient/d and 9.2 (5.9) g/bed/d. Total chemical waste was classified in four categories, chemical reagents comprising 18.2%, solvents with 52.3%, dyes and tracers with 18.2% and

  12. The Case for Requiring Graphic Warning Labels on Smokeless Tobacco Product Packages.

    Science.gov (United States)

    Pakhale, Smita; Samet, Jonathan; Folan, Patricia; Leone, Frank; White, Alexander

    2016-03-01

    On November 10, 2015, the U.S. Food and Drug Administration approved, for the first time, the sale of smokeless tobacco products authorized under the new premarket tobacco application pathway. This Food and Drug Administration regulatory decision draws attention to the growing worldwide use of smokeless tobacco products in general. Use of these tobacco products is particularly popular in low- and middle-income countries of Asia. Due to aggressive and strategic marketing to children, young adults, and current smokers, rates of smokeless tobacco use in men of all ages are on the rise in United States and elsewhere. The tobacco industry also continues to market these products to current cigarette smokers for use in the growing number of "smoke-free environments." Smokeless tobacco products are associated with cancers of the upper aerodigestive tract, particularly the oral cavity, esophagus, and pancreas; cardiovascular diseases; small-for-gestational-age infants; premature births; increased risk of apnea; and stillbirth. There is no convincing evidence regarding the efficacy of smokeless tobacco, including snus, to promote smoking cessation. Rather, studies from Europe and the United States demonstrate that smokeless tobacco use may facilitate regular cigarette smoking by acting as a gateway drug, especially for children. Caution is warranted before proposing smokeless tobacco as a harm-reduction strategy, in part because of the potential for further promoting smokeless tobacco in low- and middle-income countries where use is already widespread. Continued vigilance through comprehensive surveillance is warranted. We strongly recommend the use of graphic warning labels as a "no regrets" strategy for all smokeless tobacco products marketed globally.

  13. Generalized Kutta–Joukowski theorem for multi-vortex and multi-airfoil flow with vortex production — A general model

    Directory of Open Access Journals (Sweden)

    Bai Chenyuan

    2014-10-01

    Full Text Available By using a special momentum approach and with the help of interchange between singularity velocity and induced flow velocity, we derive in a physical way explicit force formulas for two-dimensional inviscid flow involving multiple bound and free vortices, multiple airfoils, and vortex production. These force formulas hold individually for each airfoil thus allowing for force decomposition, and the contributions to forces from singularities (such as bound and image vortices, sources, and doublets and bodies out of an airfoil are related to their induced velocities at the locations of singularities inside this airfoil. The force contribution due to vortex production is related to the vortex production rate and the distance between each pair of vortices in production, thus frame-independent. The formulas are validated against a number of standard problems. These force formulas, which generalize the classic Kutta–Joukowski theorem (for a single bound vortex and the recent generalized Lagally theorem (for problems without a bound vortex and vortex production to more general cases, can be used to identify or understand the roles of outside vortices and bodies on the forces of the actual body, optimize arrangement of outside vortices and bodies for force enhancement or reduction, and derive analytical force formulas once the flow field is given or known.

  14. Minimum iron requirements of marine phytoplankton and the implications for the biogeochemical control of new production

    International Nuclear Information System (INIS)

    Brand, L.E.

    1991-01-01

    The Fe:PO 4 ratio at which nutrient limitation of final cell yield shifts from one nutrient to the other was determined for 22 species of marine phytoplankton. Among eucaryotic phytoplankton, coastal species have subsistence optimum Fe:P molar ratios of 10 -2 to 10 -3.1 , but most oceanic species have ratios of -4 , indicating that oceanic species have been able to adapt their biochemical composition to the low availability of Fe in the open ocean. In contrast, both coastal and oceanic species of cyanobacteria have relatively high Fe:P molar ratio requirements, ranging from 10 -1.4 to 10 -2.7 . A simple comparison of these requirement ratios with the ratios of the Fe and PO 4 fluxes to the photic zone from deep water and the atmosphere indicates that new production of cyanobacterial biomass is Fe limited, but new production of eucaryotic algal biomass is not. Because of the large differences among species in their Fe requirements, especially between procaryotes and eucaryotes, changes in the relative inputs of Fe and PO 4 to the photic zone are expected to lead to changes in the species composition of phytoplankton communities. Indeed, the ratio of atmospheric to deep-water inputs of nutrients and the resulting Fe:P input ratios appear to influence the relative abundance of unicellular cyanobacteria and Trichodesmium and their vertical and biogeographic distributions. Because some phytoplankton species have adaptations that reduce their dependence on combined N and Fe but not on P, it is concluded that PO 4 is the ultimate limiting nutrient of new production of organic C on a geochemical and evolutionary time scale, even though N and Fe are important growth rate-limiting nutrients on an ecological time scale

  15. Analyzing the requirements for mass production of small wind turbine generators

    Science.gov (United States)

    Anuskiewicz, T.; Asmussen, J.; Frankenfield, O.

    Mass producibility of small wind turbine generators to give manufacturers design and cost data for profitable production operations is discussed. A 15 kW wind turbine generator for production in annual volumes from 1,000 to 50,000 units is discussed. Methodology to cost the systems effectively is explained. The process estimate sequence followed is outlined with emphasis on the process estimate sheets compiled for each component and subsystem. These data enabled analysts to develop cost breakdown profiles crucial in manufacturing decision-making. The appraisal also led to various design recommendations including replacement of aluminum towers with cost effective carbon steel towers. Extensive cost information is supplied in tables covering subassemblies, capital requirements, and levelized energy costs. The physical layout of the plant is depicted to guide manufacturers in taking advantage of the growing business opportunity now offered in conjunction with the national need for energy development.

  16. Regulatory requirements for the use of consumer products containing radioactive substances

    International Nuclear Information System (INIS)

    Mason, G.C.; Paynter, R.A.; Schmitt-Hannig, A.; Sztanyik, L.B.

    1996-01-01

    In almost 100 years since the discovery of radioactivity, the properties of radioactive materials have been exploited in products such as clocks and watches incorporating luminous paint which are freely available to members of the public. Over time, regulatory authorities have felt it necessary to apply some degree of control to the supply and use of such products in order to protect public health. In many areas of radiation protection, national authorities take note of international recommendations when developing national standards, but the existing detailed guidance of the International Atomic Energy Agency (IAEA) for consumer products is incomplete and out of date. Recently, a thorough revision of the International Basic Safety Standards (BSS) has occurred, which has prompted a review and revision of the related guidance published by the IAEA. A draft Guide on Regulatory Requirements for the Use of Consumer Products Containing Radioactive Substances has now been completed and is currently under review within the IAEA's system for development of documents in its Safety Series of publications. (author)

  17. Production of environmentally friendly aerated concrete with required construction and operational properties

    Directory of Open Access Journals (Sweden)

    Tkach Evgeniya

    2018-01-01

    Full Text Available The purpose of these studies is to justify the feasibility of recycling different types of industrial waste instead of conventional expensive raw materials in production of environmentally friendly aerated concrete with required construction and operational properties. The impact of wastes from various industries on the environmental condition of affected areas, as well as the results of their environmental assessment were analyzed to determine whether these wastes could be used in production of high-performance building materials. The assessment of industrial wastes in aerated concrete production suggests that industrial wastes of hazard class IV can be recycled to produce aerated concrete. An environmentally friendly method for large-scale waste recycling, including a two-step environmentally sustainable mechanism, was developed. The basic quality indicators of the modified aerated concrete proved that the environmental safety could be enhanced by strengthening the structure, increasing its uniformity and improving thermal insulation properties. The modified non-autoclaved aerated concrete products with improved physical and operational properties were developed. They have the following properties: density – D700; class of concrete – B3.5; thermal transmittance coefficient – 0.143 W/(m·°C; frost resistance – F75.

  18. A comparison of immunotoxic effects of nanomedicinal products with regulatory immunotoxicity testing requirements

    Directory of Open Access Journals (Sweden)

    Giannakou C

    2016-06-01

    Full Text Available Christina Giannakou,1,2 Margriet VDZ Park,1 Wim H de Jong,1 Henk van Loveren,1,2 Rob J Vandebriel,1 Robert E Geertsma1 1Centre for Health Protection, National Institute for Public Health and the Environment (RIVM, Bilthoven, 2Department of Toxicogenomics, Maastricht University, Maastricht, the Netherlands Abstract: Nanomaterials (NMs are attractive for biomedical and pharmaceutical applications because of their unique physicochemical and biological properties. A major application area of NMs is drug delivery. Many nanomedicinal products (NMPs currently on the market or in clinical trials are most often based on liposomal products or polymer conjugates. NMPs can be designed to target specific tissues, eg, tumors. In virtually all cases, NMPs will eventually reach the immune system. It has been shown that most NMs end up in organs of the mononuclear phagocytic system, notably liver and spleen. Adverse immune effects, including allergy, hypersensitivity, and immunosuppression, have been reported after NMP administration. Interactions of NMPs with the immune system may therefore constitute important side effects. Currently, no regulatory documents are specifically dedicated to evaluate the immunotoxicity of NMs or NMPs. Their immunotoxicity assessment is performed based on existing guidelines for conventional substances or medicinal products. Due to the unique properties of NMPs when compared with conventional medicinal products, it is uncertain whether the currently prescribed set of tests provides sufficient information for an adequate evaluation of potential immunotoxicity of NMPs. The aim of this study was therefore, to compare the current regulatory immunotoxicity testing requirements with the accumulating knowledge on immunotoxic effects of NMPs in order to identify potential gaps in the safety assessment. This comparison showed that immunotoxic effects, such as complement activation-related pseudoallergy, myelosuppression, inflammasome

  19. Impacts of CO2 Enrichment on Productivity and Light Requirements of Eelgrass.

    Science.gov (United States)

    Zimmerman, R. C.; Kohrs, D. G.; Steller, D. L.; Alberte, R. S.

    1997-10-01

    Seagrasses, although well adapted for submerged existence, are CO2-limited and photosynthetically inefficient in seawater. This leads to high light requirements for growth and survival and makes seagrasses vulnerable to light limitation. We explored the long-term impact of increased CO2 availability on light requirements, productivity, and C allocation in eelgrass (Zostera marina L.). Enrichment of seawater CO2 increased photosynthesis 3-fold, but had no long-term impact on respiration. By tripling the rate of light-saturated photosynthesis, CO2 enrichment reduced the daily period of irradiance-saturated photosynthesis (Hsat) that is required for the maintenance of positive whole-plant C balance from 7 to 2.7 h, allowing plants maintained under 4 h of Hsat to perform like plants growing in unenriched seawater with 12 h of Hsat. Eelgrass grown under 4 h of Hsat without added CO2 consumed internal C reserves as photosynthesis rates and chlorophyll levels dropped. Growth ceased after 30 d. Leaf photosynthesis, respiration, chlorophyll, and sucrose-phosphate synthase activity of CO2-enriched plants showed no acclimation to prolonged enrichment. Thus, the CO2-stimulated improvement in photosynthesis reduced light requirements in the long term, suggesting that globally increasing CO2 may enhance seagrass survival in eutrophic coastal waters, where populations have been devastated by algal proliferation and reduced water-column light transparency.

  20. How wing kinematics affect power requirements and aerodynamic force production in a robotic bat wing

    International Nuclear Information System (INIS)

    Bahlman, Joseph W; Swartz, Sharon M; Breuer, Kenneth S

    2014-01-01

    Bats display a wide variety of behaviors that require different amounts of aerodynamic force. To control and modulate aerodynamic force, bats change wing kinematics, which, in turn, may change the power required for wing motion. There are many kinematic mechanisms that bats, and other flapping animals, can use to increase aerodynamic force, e.g. increasing wingbeat frequency or amplitude. However, we do not know if there is a difference in energetic cost between these different kinematic mechanisms. To assess the relationship between mechanical power input and aerodynamic force output across different isolated kinematic parameters, we programmed a robotic bat wing to flap over a range of kinematic parameters and measured aerodynamic force and mechanical power. We systematically varied five kinematic parameters: wingbeat frequency, wingbeat amplitude, stroke plane angle, downstroke ratio, and wing folding. Kinematic values were based on observed values from free flying Cynopterus brachyotis, the species on which the robot was based. We describe how lift, thrust, and power change with increases in each kinematic variable. We compare the power costs associated with generating additional force through the four kinematic mechanisms controlled at the shoulder, and show that all four mechanisms require approximately the same power to generate a given force. This result suggests that no single parameter offers an energetic advantage over the others. Finally, we show that retracting the wing during upstroke reduces power requirements for flapping and increases net lift production, but decreases net thrust production. These results compare well with studies performed on C. brachyotis, offering insight into natural flight kinematics. (paper)

  1. General Principles for the welfare of animals in production systems: the underlying science and its application.

    Science.gov (United States)

    Fraser, David; Duncan, Ian J H; Edwards, Sandra A; Grandin, Temple; Gregory, Neville G; Guyonnet, Vincent; Hemsworth, Paul H; Huertas, Stella M; Huzzey, Juliana M; Mellor, David J; Mench, Joy A; Spinka, Marek; Whay, H Rebecca

    2013-10-01

    In 2012, the World Organisation for Animal Health adopted 10 'General Principles for the Welfare of Animals in Livestock Production Systems' to guide the development of animal welfare standards. The General Principles draw on half a century of scientific research relevant to animal welfare: (1) how genetic selection affects animal health, behaviour and temperament; (2) how the environment influences injuries and the transmission of diseases and parasites; (3) how the environment affects resting, movement and the performance of natural behaviour; (4) the management of groups to minimize conflict and allow positive social contact; (5) the effects of air quality, temperature and humidity on animal health and comfort; (6) ensuring access to feed and water suited to the animals' needs and adaptations; (7) prevention and control of diseases and parasites, with humane euthanasia if treatment is not feasible or recovery is unlikely; (8) prevention and management of pain; (9) creation of positive human-animal relationships; and (10) ensuring adequate skill and knowledge among animal handlers. Research directed at animal welfare, drawing on animal behaviour, stress physiology, veterinary epidemiology and other fields, complements more established fields of animal and veterinary science and helps to create a more comprehensive scientific basis for animal care and management. Copyright © 2013 Elsevier Ltd. All rights reserved.

  2. 18 CFR 292.209 - Exceptions from requirements for hydroelectric small power production facilities located at a new...

    Science.gov (United States)

    2010-04-01

    ... requirements for hydroelectric small power production facilities located at a new dam or diversion. 292.209... Exceptions from requirements for hydroelectric small power production facilities located at a new dam or... the Federal Power Act, at which non-Federal hydroelectric development is permissible; or (2) An...

  3. 21 CFR 111.60 - What are the design requirements for the production and process control system?

    Science.gov (United States)

    2010-04-01

    ... to Establish a Production and Process Control System § 111.60 What are the design requirements for... 21 Food and Drugs 2 2010-04-01 2010-04-01 false What are the design requirements for the production and process control system? 111.60 Section 111.60 Food and Drugs FOOD AND DRUG ADMINISTRATION...

  4. 21 CFR 610.68 - Exceptions or alternatives to labeling requirements for biological products held by the Strategic...

    Science.gov (United States)

    2010-04-01

    ... requirements for biological products held by the Strategic National Stockpile. 610.68 Section 610.68 Food and... requirements for biological products held by the Strategic National Stockpile. (a) The appropriate FDA Center... Strategic National Stockpile. (b)(1)(i) A Strategic National Stockpile official or any entity that...

  5. Product of the powers of generalized Nakagami-m variates and performance of cascaded fading channels

    KAUST Repository

    Yilmaz, Ferkan

    2009-11-01

    In this paper, we analyze the fading statistics of a generic fading distribution, termed the N-product Generalized Nakagami-m (GNM) distribution (N*GNM distribution), constructed as the product of the power of N statistically independent and non-identically distributed GNM random variables, for the purpose of modeling the cascaded fading channels. In particular, using the Fox\\'s H function, we derive the probability density function, the cumulative distribution function, the moment generating function and the moments of such channels in closed-form. These derived results are a convenient tool to statistically model the cascaded GNM fading channels and to analyze the performance of digital communication systems over these kinds of channels. As such, generic closed-form expressions for the amount of fading, the outage probability, the capacity, the outage capacity and the average bit error probabilities of digital communications systems over cascaded GNM fading channels are presented. Numerical and simulation results, performed to verify the correctness of the proposed formulation, are in perfect agreement.

  6. Single Higgs-boson production at a photon-photon collider: General 2HDM versus MSSM

    Energy Technology Data Exchange (ETDEWEB)

    Lopez-Val, David, E-mail: lopez@thphys.uni-heidelberg.de [Institut fuer Theoretische Physik, Universitaet Heidelberg, Philosophenweg 16, D-69120 Heidelberg (Germany); Sola, Joan, E-mail: sola@ecm.ub.es [High Energy Physics Group, Dept. ECM, and Institut de Ciencies del Cosmos Univ. de Barcelona, Av. Diagonal 647, E-08028 Barcelona, Catalonia (Spain)

    2011-08-19

    We revisit the production of a single Higgs boson from direct {gamma}{gamma}-scattering at a photon collider. We compute the total cross-section {sigma}({gamma}{gamma}{yields}h) (for h=h{sup 0},H{sup 0},A{sup 0}), and the strength of the effective g{sub h}{sup 0}{sub {gamma}{gamma}} coupling normalized to the Standard Model (SM), for both the general Two-Higgs-Doublet Model (2HDM) and the Minimal Supersymmetric Standard Model (MSSM). In both cases the predicted production rates for the CP-even (odd) states render up to 10{sup 4} (10{sup 3}) events per 500 fb{sup -1} of integrated luminosity, in full consistency with all the theoretical and phenomenological constraints. Depending on the channel the maximum rates can be larger or smaller than the SM expectations, but in most of the parameter space they should be well measurable. We analyze how these departures depend on the dynamics underlying each of the models, supersymmetric and non-supersymmetric, and highlight the possible distinctive phenomenological signatures. We demonstrate that this process could be extremely useful to discern non-supersymmetric Higgs bosons from supersymmetric ones. Furthermore, in the MSSM case, we show that {gamma}{gamma}-physics could decisively help to overcome the serious impasse afflicting Higgs boson physics at the infamous 'LHC wedge'.

  7. Composition and production rate of pharmaceutical and chemical waste from Xanthi General Hospital in Greece.

    Science.gov (United States)

    Voudrias, Evangelos; Goudakou, Lambrini; Kermenidou, Marianthi; Softa, Aikaterini

    2012-07-01

    The objective of this work was to determine the composition and production rates of pharmaceutical and chemical waste produced by Xanthi General Hospital in Greece (XGH). This information is important to design and cost management systems for pharmaceutical and chemical waste, for safety and health considerations and for assessing environmental impact. A total of 233 kg pharmaceutical and 110 kg chemical waste was collected, manually separated and weighed over a period of five working weeks. The total production of pharmaceutical waste comprised 3.9% w/w of the total hazardous medical waste produced by the hospital. Total pharmaceutical waste was classified in three categories, vial waste comprising 51.1%, syringe waste with 11.4% and intravenous therapy (IV) waste with 37.5% w/w of the total. Vial pharmaceutical waste only was further classified in six major categories: antibiotics, digestive system drugs, analgesics, hormones, circulatory system drugs and "other". Production data below are presented as average (standard deviation in parenthesis). The unit production rates for total pharmaceutical waste for the hospital were 12.4 (3.90) g/patient/d and 24.6 (7.48) g/bed/d. The respective unit production rates were: (1) for vial waste 6.4 (1.6) g/patient/d and 13 (2.6) g/bed/d, (2) for syringe waste 1.4 (0.4) g/patient/d and 2.8 (0.8) g/bed/d and (3) for IV waste 4.6 (3.0) g/patient/d and 9.2 (5.9) g/bed/d. Total chemical waste was classified in four categories, chemical reagents comprising 18.2%, solvents with 52.3%, dyes and tracers with 18.2% and solid waste with 11.4% w/w of the total. The total production of chemical waste comprised 1.8% w/w of the total hazardous medical waste produced by the hospital. Thus, the sum of pharmaceutical and chemical waste was 5.7% w/w of the total hazardous medical waste produced by the hospital. The unit production rates for total chemical waste for the hospital were 5.8 (2.2) g/patient/d and 1.1 (0.4) g/exam/d. The respective

  8. Effects of copper on CHO cells: cellular requirements and product quality considerations.

    Science.gov (United States)

    Yuk, Inn H; Russell, Stephen; Tang, Yun; Hsu, Wei-Ting; Mauger, Jacob B; Aulakh, Rigzen P S; Luo, Jun; Gawlitzek, Martin; Joly, John C

    2015-01-01

    Recent reports highlight the impact of copper on lactate metabolism: CHO cell cultures with higher initial copper levels shift to net lactate consumption and yield lower final lactate and higher titers. These studies investigated the effects of copper on metabolite and transcript profiles, but did not measure in detail the dependences of cell culture performance and product quality on copper concentrations. To more thoroughly map these dependences, we explored the effects of various copper treatments on four recombinant CHO cell lines. In the first cell line, when extracellular copper remained above the limit of detection (LOD), cultures shifted to net lactate consumption and yielded comparable performances irrespective of the differences in copper levels; when extracellular copper dropped below LOD (∼13 nM), cultures failed to shift to net lactate consumption, and yielded significantly lower product titers. Across the four cell lines, the ability to grow and consume lactate seemed to depend on the presence of a minimum level of copper, beyond which there were no further gains in culture performance. Although this minimum cellular copper requirement could not be directly quantified, we estimated its probable range for the first cell line by applying several assumptions. Even when different copper concentrations did not affect cell culture performance, they affected product quality profiles: higher initial copper concentrations increased the basic variants in the recombinant IgG1 products. Therefore, in optimizing chemically defined media, it is important to select a copper concentration that is adequate and achieves desired product quality attributes. © 2014 American Institute of Chemical Engineers.

  9. 18 CFR 292.208 - Special requirements for hydroelectric small power production facilities located at a new dam or...

    Science.gov (United States)

    2010-04-01

    ... for hydroelectric small power production facilities located at a new dam or diversion. 292.208 Section... requirements for hydroelectric small power production facilities located at a new dam or diversion. (a) A hydroelectric small power production facility that impounds or diverts the water of a natural watercourse by...

  10. 21 CFR 201.26 - Exceptions or alternatives to labeling requirements for human drug products held by the Strategic...

    Science.gov (United States)

    2010-04-01

    ... requirements for human drug products held by the Strategic National Stockpile. 201.26 Section 201.26 Food and... drug products held by the Strategic National Stockpile. (a) The appropriate FDA Center Director may... safety, effectiveness, or availability of such product that is or will be included in the Strategic...

  11. 9 CFR 381.172 - Requirements for substitute standardized poultry products named by use of an expressed nutrient...

    Science.gov (United States)

    2010-01-01

    ... AGRICULTURE AGENCY ORGANIZATION AND TERMINOLOGY; MANDATORY MEAT AND POULTRY PRODUCTS INSPECTION AND VOLUNTARY... properties, functional properties, and shelf-life, of the poultry product shall be similar to those of the... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false Requirements for substitute...

  12. The Aspergillus flavus Homeobox Gene, hbx1, Is Required for Development and Aflatoxin Production

    Directory of Open Access Journals (Sweden)

    Jeffrey W. Cary

    2017-10-01

    Full Text Available Homeobox proteins, a class of well conserved transcription factors, regulate the expression of targeted genes, especially those involved in development. In filamentous fungi, homeobox genes are required for normal conidiogenesis and fruiting body formation. In the present study, we identified eight homeobox (hbx genes in the aflatoxin-producing ascomycete, Aspergillus flavus, and determined their respective role in growth, conidiation and sclerotial production. Disruption of seven of the eight genes had little to no effect on fungal growth and development. However, disruption of the homeobox gene AFLA_069100, designated as hbx1, in two morphologically different A. flavus strains, CA14 and AF70, resulted in complete loss of production of conidia and sclerotia as well as aflatoxins B1 and B2, cyclopiazonic acid and aflatrem. Microscopic examination showed that the Δhbx1 mutants did not produce conidiophores. The inability of Δhbx1 mutants to produce conidia was related to downregulation of brlA (bristle and abaA (abacus, regulatory genes for conidiophore development. These mutants also had significant downregulation of the aflatoxin pathway biosynthetic genes aflC, aflD, aflM and the cluster-specific regulatory gene, aflR. Our results demonstrate that hbx1 not only plays a significant role in controlling A. flavus development but is also critical for the production of secondary metabolites, such as aflatoxins.

  13. Productive whole-class discussions: A qualitative analysis of peer leader behaviors in general chemistry

    Science.gov (United States)

    Eckart, Teresa Mcclain

    The intention of this research was to describe behaviors and characteristics of General Chemistry I peer leaders using a pedagogical reform method referred to as Peer-led Guided Inquiry (PLGI), and to discuss the ways in which these peer leaders created productive whole-class discussions. This reform technique engaged students to work on guided inquiry activities while working cooperatively in small groups, led by undergraduate peer leaders. These sessions were video recorded and transcribed. The data was evaluated using grounded theory methods of analysis. This study examined the dialog between students and peer leaders, paying specific attention to question types and observed patterns of interactions. The research took shape by examining the kinds of questions asked by peer leaders and the purposes these questions served. In addition to looking at questions, different kinds of behaviors displayed by peer leaders during their small group sessions were also observed. A close examination of peer leader questions and behaviors aided in developing an answer to the overall research question regarding what factors are associated with productive whole-class discussions. Five major categories of peer leader behaviors evolved from the data and provided a means to compare and contrast productive whole-class discussions. While no category single-handedly determined if a discussion was good or bad, there was a tendency for peer leaders who exhibited positive traits in at least three of the following categories to have consistently better whole-class discussions: Procedural Practices, Supervisory Qualities, Questioning Techniques, Feedback/Responses, and Interpersonal Skills. Furthermore, each of the major categories is tied directly to Interpersonal, Communication, and Leadership skills and their interactions with each other. This study also addressed applications that each of these categories has on instructional practices and their need in peer leader training. In addition

  14. Boundedness and compactness of a new product-type operator from a general space to Bloch-type spaces

    Directory of Open Access Journals (Sweden)

    Stevo Stević

    2016-09-01

    Full Text Available Abstract We characterize the boundedness and compactness of a product-type operator, which, among others, includes all the products of the single composition, multiplication, and differentiation operators, from a general space to Bloch-type spaces. We also give some upper and lower bounds for the norm of the operator.

  15. A comparison of immunotoxic effects of nanomedicinal products with regulatory immunotoxicity testing requirements.

    Science.gov (United States)

    Giannakou, Christina; Park, Margriet Vdz; de Jong, Wim H; van Loveren, Henk; Vandebriel, Rob J; Geertsma, Robert E

    2016-01-01

    Nanomaterials (NMs) are attractive for biomedical and pharmaceutical applications because of their unique physicochemical and biological properties. A major application area of NMs is drug delivery. Many nanomedicinal products (NMPs) currently on the market or in clinical trials are most often based on liposomal products or polymer conjugates. NMPs can be designed to target specific tissues, eg, tumors. In virtually all cases, NMPs will eventually reach the immune system. It has been shown that most NMs end up in organs of the mononuclear phagocytic system, notably liver and spleen. Adverse immune effects, including allergy, hypersensitivity, and immunosuppression, have been reported after NMP administration. Interactions of NMPs with the immune system may therefore constitute important side effects. Currently, no regulatory documents are specifically dedicated to evaluate the immunotoxicity of NMs or NMPs. Their immunotoxicity assessment is performed based on existing guidelines for conventional substances or medicinal products. Due to the unique properties of NMPs when compared with conventional medicinal products, it is uncertain whether the currently prescribed set of tests provides sufficient information for an adequate evaluation of potential immunotoxicity of NMPs. The aim of this study was therefore, to compare the current regulatory immunotoxicity testing requirements with the accumulating knowledge on immunotoxic effects of NMPs in order to identify potential gaps in the safety assessment. This comparison showed that immunotoxic effects, such as complement activation-related pseudoallergy, myelosuppression, inflammasome activation, and hypersensitivity, are not readily detected by using current testing guidelines. Immunotoxicity of NMPs would be more accurately evaluated by an expanded testing strategy that is equipped to stratify applicable testing for the various types of NMPs.

  16. Pyranose dehydrogenase ligand promiscuity: a generalized approach to simulate monosaccharide solvation, binding, and product formation.

    Directory of Open Access Journals (Sweden)

    Michael M H Graf

    2014-12-01

    Full Text Available The flavoenzyme pyranose dehydrogenase (PDH from the litter decomposing fungus Agaricus meleagris oxidizes many different carbohydrates occurring during lignin degradation. This promiscuous substrate specificity makes PDH a promising catalyst for bioelectrochemical applications. A generalized approach to simulate all 32 possible aldohexopyranoses in the course of one or a few molecular dynamics (MD simulations is reported. Free energy calculations according to the one-step perturbation (OSP method revealed the solvation free energies (ΔGsolv of all 32 aldohexopyranoses in water, which have not yet been reported in the literature. The free energy difference between β- and α-anomers (ΔGβ-α of all d-stereoisomers in water were compared to experimental values with a good agreement. Moreover, the free-energy differences (ΔG of the 32 stereoisomers bound to PDH in two different poses were calculated from MD simulations. The relative binding free energies (ΔΔGbind were calculated and, where available, compared to experimental values, approximated from Km values. The agreement was very good for one of the poses, in which the sugars are positioned in the active site for oxidation at C1 or C2. Distance analysis between hydrogens of the monosaccharide and the reactive N5-atom of the flavin adenine dinucleotide (FAD revealed that oxidation is possible at HC1 or HC2 for pose A, and at HC3 or HC4 for pose B. Experimentally detected oxidation products could be rationalized for the majority of monosaccharides by combining ΔΔGbind and a reweighted distance analysis. Furthermore, several oxidation products were predicted for sugars that have not yet been tested experimentally, directing further analyses. This study rationalizes the relationship between binding free energies and substrate promiscuity in PDH, providing novel insights for its applicability in bioelectrochemistry. The results suggest that a similar approach could be applied to study

  17. Sterilization of health care products - Ethylene oxide - Part 1: Requirements for development, validation and routine control of a sterilization process for medical devices

    International Nuclear Information System (INIS)

    2007-01-01

    This part of ISO 11135 describes requirements that, if met, will provide an ethylene oxide sterilization process intended to sterilize medical devices, which has appropriate microbicidal activity. Furthermore, compliance with the requirements ensures that this activity is both reliable and reproducible so that it can be predicted, with reasonable confidence, that there is a low level of probability of there being a viable microorganism present on product after sterilization. Specification of this probability is a matter for regulatory authorities and may vary from country to country. The paper provides information on scope, normative references, terms and definitions, quality management systems, sterilizing agent characterization, process and equipment characterization, product definition, process definition, validation, routine monitoring and control, product release from sterilization and maintaining process effectiveness followed by Annex A (Determination of lethal rate of the sterilization process - Biological indicator/bioburden approach), Annex B (Conservative determination of lethal rate of the sterilization process - Overkill approach, annex C (General guidance) and a bibliography.

  18. Generalized hypercube graph $\\Q_n(S$, graph products and self-orthogonal codes

    Directory of Open Access Journals (Sweden)

    Pani Seneviratne

    2016-01-01

    Full Text Available A generalized hypercube graph $\\Q_n(S$ has $\\F_{2}^{n}=\\{0,1\\}^n$ as the vertex set and two vertices being adjacent whenever their mutual Hamming distance belongs to $S$, where $n \\ge 1$ and $S\\subseteq \\{1,2,\\ldots, n\\}$. The graph $\\Q_n(\\{1\\}$ is the $n$-cube, usually denoted by $\\Q_n$.We study graph boolean products $G_1 = \\Q_n(S\\times \\Q_1, G_2 = \\Q_{n}(S\\wedge \\Q_1$, $G_3 = \\Q_{n}(S[\\Q_1]$ and show that binary codes from neighborhood designs of $G_1, G_2$ and $G_3$ are self-orthogonal for all choices of $n$ and $S$. More over, we show that the class of codes $C_1$ are self-dual. Further we find subgroups of the automorphism group of these graphs and use these subgroups to obtain PD-sets for permutation decoding. As an example we find a full error-correcting PD set for the binary $[32, 16, 8]$ extremal self-dual code.

  19. Power requirements at the VHTR/HTE interface for hydrogen production

    International Nuclear Information System (INIS)

    Vilim, R.B.

    2007-01-01

    The power requirements at the interface between the High Temperature Electrolysis (HTE) process and the Very High Temperature Reactor (VHTR) were investigated. The study was performed using a network systems code that linked together individual component models for boiler, condenser, turbine, compressor, pump, gas-to-gas heat exchanger, electrolyser, and reactor and properties for water, hydrogen, oxygen, nitrogen, and helium. A species mixture model supported the use of mixtures of gases in each component model. The requirements for a reference design with a dedicated high temperature process heat loop are given. In general the quantity and quality of the process heat needed by the HTE process is a function of how the electrolyser is operated. Operating at higher voltage increases throughput and resistive heating providing the opportunity to recuperate this heat and supplant a large fraction of high temperature reactor heat. Any shortfall can be added by electrical heaters in the HTE plant. Eliminating the associated high temperature heat exchanger from the nuclear plant in this manner would significantly improve safety and maintainability. Low temperature process heat is still needed to vaporize water for the HTE process but this can be obtained at very low cost from VHTR waste heat rejected to the ultimate heat sink. (author)

  20. Unfolded protein response is required for Aspergillus oryzae growth under conditions inducing secretory hydrolytic enzyme production.

    Science.gov (United States)

    Tanaka, Mizuki; Shintani, Takahiro; Gomi, Katsuya

    2015-12-01

    Unfolded protein response (UPR) is an intracellular signaling pathway for adaptation to endoplasmic reticulum (ER) stress. In yeast UPR, Ire1 cleaves the unconventional intron of HAC1 mRNA, and the functional Hac1 protein translated from the spliced HAC1 mRNA induces the expression of ER chaperone genes and ER-associated degradation genes for the refolding or degradation of unfolded proteins. In this study, we constructed an ireA (IRE1 ortholog) conditionally expressing strain of Aspergillus oryzae, a filamentous fungus producing a large amount of amylolytic enzymes, and examined the contribution of UPR to ER stress adaptation under physiological conditions. Repression of ireA completely blocked A. oryzae growth under conditions inducing the production of hydrolytic enzymes, such as amylases and proteases. This growth defect was restored by the introduction of unconventional intronless hacA (hacA-i). Furthermore, UPR was observed to be induced by amylolytic gene expression, and the disruption of the transcriptional activator for amylolytic genes resulted in partial growth restoration of the ireA-repressing strain. In addition, a homokaryotic ireA disruption mutant was successfully generated using the strain harboring hacA-i as a parental host. These results indicated that UPR is required for A. oryzae growth to alleviate ER stress induced by excessive production of hydrolytic enzymes. Copyright © 2015 Elsevier Inc. All rights reserved.

  1. Nutritional Requirements for the Mycelial Biomass and Exopolymer Production by Hericium erinaceus CZ-2

    Directory of Open Access Journals (Sweden)

    Daming Huang

    2007-01-01

    Full Text Available In this work, the effects of medium composition and fermentation parameters on the simultaneous production of mycelial biomass and exopolymer by medicinal mushroom Hericium erinaceus CZ-2 were investigated in shake flask cultures using one-factor-at-a-time method and orthogonal array design. Results showed that the most suitable carbon, nitrogen, mineral sources, and cofactors for the mycelial biomass and exopolymer production were: corn flour combined with 1 % glucose, yeast extract, KH2PO4 and corn steep liquor. The intuitive analysis of orthogonal array design results indicated that the effects of nutritional requirement on the mycelial growth of Hericium erinaceus CZ-2 were in regular sequence of corn flour combined with 1 % glucose > yeast extract > corn steep liquor > KH2PO4, and those on exopolymer production were in the order of corn flour combined with glucose > KH2PO4 > yeast extract > corn steep liquor. The maximal yield of mycelial biomass (16.07 g/L was obtained when the composition of the culture medium was (in g/L: corn flour 30, glucose 10, yeast extract 3, KH2PO4 1, CaCO3 0.5, and 15 mL/L of corn steep liquor; while the maximal exopolymer yield (1.314 g/L was achieved when the composition of medium was (in g/L: corn flour 30, glucose 10, yeast extract 5, KH2PO4 3, CaCO3 0.5, and 15 mL/L of corn steep liquor. In the 15-litre scale-up fermentation, the maximum mycelial biomass yield of 20.50 g/L was achieved using the optimized medium.

  2. Needs and accuracy requirements for fission product nuclear data in the physics design of power reactor cores

    International Nuclear Information System (INIS)

    Rowlands, J.L.

    1978-01-01

    The fission product nuclear data accuracy requirements for fast and thermal reactor core performance predictions were reviewed by Tyror at the Bologna FPND Meeting. The status of the data was assessed at the Meeting and it was concluded that the requirements of thermal reactors were largely met, and the yield data requirements of fast reactors, but not the cross section requirements, were met. However, the World Request List for Nuclear Data (WRENDA) contains a number of requests for fission product capture cross sections in the energy range of interest for thermal reactors. Recent reports indicate that the fast reactor reactivity requirements might have been met by integral measurements made in zero power critical assemblies. However, there are requests for the differential cross sections of the individual isotopes to be determined in addition to the integral data requirements. The fast reactor requirements are reviewed, taking into account some more recent studies of the effects of fission products. The sodium void reactivity effect depends on the fission product cross sections in a different way to the fission product reactivity effect in a normal core. This requirement might call for different types of measurement. There is currently an interest in high burnup fuel cycles and alternative fuel cycles. These might require more accurate fission product data, data for individual isotopes and data for capture products. Recent calculations of the time dependence of fission product reactivity effects show that this is dependent upon the data set used and there are significant uncertainties. Some recent thermal reactor studies on approximations in the treatment of decay chains and the importance of xenon and samarium poisoning are also summarized. (author)

  3. 9 CFR 381.150 - Requirements for the production of fully cooked poultry products and partially cooked poultry...

    Science.gov (United States)

    2010-01-01

    ... fully cooked poultry products and partially cooked poultry breakfast strips. 381.150 Section 381.150... ORGANIZATION AND TERMINOLOGY; MANDATORY MEAT AND POULTRY PRODUCTS INSPECTION AND VOLUNTARY INSPECTION AND CERTIFICATION POULTRY PRODUCTS INSPECTION REGULATIONS Entry of Articles Into Official Establishments; Processing...

  4. Does body size of dairy cows, at constant ratio of maintenance to production requirements, affect productivity in a pasture-based production system?

    Science.gov (United States)

    Hofstetter, P; Steiger Burgos, M; Petermann, R; Münger, A; Blum, J W; Thomet, P; Menzi, H; Kohler, S; Kunz, P

    2011-12-01

    This study compared productivity of dairy cows with different body weight (BW), but a constant ratio of maintenance to production requirements in their first lactation, in a pasture-based production system with spring calving. Two herds, Herd L (13 and 14 large cows in 2003 and 2004 respectively; average BW after calving, 721 kg) and Herd S (16 small cows in both years; 606 kg) [Correction added after online publication 14 January 2011: 16 small cows in both years; 621 kg was changed to 16 small cows in both years; 606 kg], all in their second or following lactations, were each allocated 6 ha of pasture and rotationally grazed on 10 parallel paddocks with equal herbage offer and nutritional values. Winter hay, harvested from the same pastures, was offered ad libitum in the indoor periods in a tied stall barn. Each herd received, per lactation and year, approximately 2000 kg dry matter (DM) of concentrates and of fodder beets, equally distributed to every individual. Indoors, the L-cows ingested more DM than the S-cows (18.7 vs. 16.3 kg DM/cow per day; p pasture (17.9 vs. 15.5 kg DM/cow per day; p dairy cow types were equally efficient in utilising pasture-based forage. © 2010 Blackwell Verlag GmbH.

  5. Efficient eigenvalue determination for arbitrary Pauli products based on generalized spin-spin interactions

    Science.gov (United States)

    Leibfried, D.; Wineland, D. J.

    2018-03-01

    Effective spin-spin interactions between ? qubits enable the determination of the eigenvalue of an arbitrary Pauli product of dimension N with a constant, small number of multi-qubit gates that is independent of N and encodes the eigenvalue in the measurement basis states of an extra ancilla qubit. Such interactions are available whenever qubits can be coupled to a shared harmonic oscillator, a situation that can be realized in many physical qubit implementations. For example, suitable interactions have already been realized for up to 14 qubits in ion traps. It should be possible to implement stabilizer codes for quantum error correction with a constant number of multi-qubit gates, in contrast to typical constructions with a number of two-qubit gates that increases as a function of N. The special case of finding the parity of N qubits only requires a small number of operations that is independent of N. This compares favorably to algorithms for computing the parity on conventional machines, which implies a genuine quantum advantage.

  6. Occupational and traning requirements for expanded coal production (as of October 1980). [Forecasting to 1995

    Energy Technology Data Exchange (ETDEWEB)

    1982-04-01

    This study was initiated because of the anticipated rapid growth in trained personnel requirements in bituminous coal mining, and because the industry had already experienced significant problems in recruiting skilled manpower in the course of its employment expansion during the 1970's. Employment in bituminous coal mining is projected to nearly double, from 234,000 in 1977 to 456,000 in 1995, as the net result of a projected threefold increase in coal output to nearly 2.0 billion in 1995 and of an expected significant improvement in overall productivity. A large proportion of current coal mining employees are in occupations which require significant amounts of training for effective work performance. Employment growth to 1955 will be most rapid in those occupations requiring the greatest training or educational preparation. The new training infrastructure which has emerged to meet these needs includes both internal, company-operated training programs and those offered by various external providers. Among the latter are: Vocational schools, community colleges, and university extension departments; public agencies, such as MSHA and state mining departments; coal industry trade associations; and vendors or training consultant groups. The Conference Board survey of coal industry training programs, conducted in late 1979, was designed to provide comprehensive data on the scope of the coal industry's own training activities and on related training issues, based on a mail questionnaire survey addressed to all companies producing 300,000 or more tons per year. The training programs are described with emphasis on time changes, regional effects and implications for a coordinated plan.

  7. Food and nutritional security requires adequate protein as well as energy, delivered from whole-year crop production.

    Science.gov (United States)

    Coles, Graeme D; Wratten, Stephen D; Porter, John R

    2016-01-01

    Human food security requires the production of sufficient quantities of both high-quality protein and dietary energy. In a series of case-studies from New Zealand, we show that while production of food ingredients from crops on arable land can meet human dietary energy requirements effectively, requirements for high-quality protein are met more efficiently by animal production from such land. We present a model that can be used to assess dietary energy and quality-corrected protein production from various crop and crop/animal production systems, and demonstrate its utility. We extend our analysis with an accompanying economic analysis of commercially-available, pre-prepared or simply-cooked foods that can be produced from our case-study crop and animal products. We calculate the per-person, per-day cost of both quality-corrected protein and dietary energy as provided in the processed foods. We conclude that mixed dairy/cropping systems provide the greatest quantity of high-quality protein per unit price to the consumer, have the highest food energy production and can support the dietary requirements of the highest number of people, when assessed as all-year-round production systems. Global food and nutritional security will largely be an outcome of national or regional agroeconomies addressing their own food needs. We hope that our model will be used for similar analyses of food production systems in other countries, agroecological zones and economies.

  8. 75 FR 52616 - Third Party Testing for Certain Children's Products; Youth All-Terrain Vehicles: Requirements for...

    Science.gov (United States)

    2010-08-27

    ... content of the ILAC-MRA approach and of the requirements of the ISO/IEC 17025:2005 laboratory... must be to ISO Standard ISO/IEC 17025:2005, General Requirements for the Competence of Testing and... that at that time was ISO/IEC 17025 accredited by an ILAC-MRA signatory. For firewalled conformity...

  9. The general transcriptional repressor Tup1 is required for dimorphism and virulence in a fungal plant pathogen.

    Directory of Open Access Journals (Sweden)

    Alberto Elías-Villalobos

    2011-09-01

    Full Text Available A critical step in the life cycle of many fungal pathogens is the transition between yeast-like growth and the formation of filamentous structures, a process known as dimorphism. This morphological shift, typically triggered by multiple environmental signals, is tightly controlled by complex genetic pathways to ensure successful pathogenic development. In animal pathogenic fungi, one of the best known regulators of dimorphism is the general transcriptional repressor, Tup1. However, the role of Tup1 in fungal dimorphism is completely unknown in plant pathogens. Here we show that Tup1 plays a key role in orchestrating the yeast to hypha transition in the maize pathogen Ustilago maydis. Deletion of the tup1 gene causes a drastic reduction in the mating and filamentation capacity of the fungus, in turn leading to a reduced virulence phenotype. In U. maydis, these processes are controlled by the a and b mating-type loci, whose expression depends on the Prf1 transcription factor. Interestingly, Δtup1 strains show a critical reduction in the expression of prf1 and that of Prf1 target genes at both loci. Moreover, we observed that Tup1 appears to regulate Prf1 activity by controlling the expression of the prf1 transcriptional activators, rop1 and hap2. Additionally, we describe a putative novel prf1 repressor, named Pac2, which seems to be an important target of Tup1 in the control of dimorphism and virulence. Furthermore, we show that Tup1 is required for full pathogenic development since tup1 deletion mutants are unable to complete the sexual cycle. Our findings establish Tup1 as a key factor coordinating dimorphism in the phytopathogen U. maydis and support a conserved role for Tup1 in the control of hypha-specific genes among animal and plant fungal pathogens.

  10. Linguistic validation of the US Spanish work productivity and activity impairment questionnaire, general health version.

    Science.gov (United States)

    Gawlicki, Mary C; Reilly, Margaret C; Popielnicki, Ana; Reilly, Kate

    2006-01-01

    There are no measures of health-related absenteeism and presenteeism validated for use in the large and increasing US Spanish-speaking population. Before using a Spanish translation of an available English-language questionnaire, the linguistic validity of the Spanish version must be established to ensure its conceptual equivalence to the original and its cultural appropriateness. The objective of this study was to evaluate the linguistic validity of the US Spanish version of the Work Productivity and Activity Impairment questionnaire, General Health Version (WPAI:GH). A US Spanish translation of the US English WPAI:GH was created through a reiterative process of creating harmonized forward and back translations by independent translators. Spanish-speaking and English-speaking subjects residing in the US self-administered the WPAI:GH in their primary language and were subsequently debriefed by a bilingual (Spanish-English) interviewer. US Spanish subjects (N = 31) and English subjects (N = 35), stratified equally by educational level, with and without a high school degree participated in the study. The WPAI-GH item comprehension rate was 98.6% for Spanish and 99.6% for English. Response revision rates during debriefing were 1.6% for Spanish and 0.5% for English. Responses to hypothetical scenarios indicated that both language versions adequately differentiate sick time taken for health and non-health reasons and between absenteeism and presenteeism. Linguistic validity of the US Spanish translation of the WPAI:GH was established among a diverse US Spanish-speaking population, including those with minimal education.

  11. Research productivity in Australian general practice: what has changed since the 1990s?

    Science.gov (United States)

    Askew, Deborah A; Schluter, Philip J; Gunn, Jane M

    2008-07-21

    The Primary Health Care Research, Evaluation and Development (PHCRED) Strategy aims to improve Australia's output of high-quality research from primary care. We compared publication rates from general practice, medicine and surgery for the period 2000-2007, and found that general practice publications increased since 1990-1999 from 1.0 to 3.0 publications per 1000 general practitioners per year. However, general practice publication rates have plateaued since 2000, and represent only 2%-5% of the equivalent rates for medicine and surgery. This finding suggests that more time and sustained investment in PHCRED are essential to see tangible outputs from funded research in general practice.

  12. Accounting for graduate medical education production of primary care physicians and general surgeons: timing of measurement matters.

    Science.gov (United States)

    Petterson, Stephen; Burke, Matthew; Phillips, Robert; Teevan, Bridget

    2011-05-01

    Legislation proposed in 2009 to expand GME set institutional primary care and general surgery production eligibility thresholds at 25% at entry into training. The authors measured institutions' production of primary care physicians and general surgeons on completion of first residency versus two to four years after graduation to inform debate and explore residency expansion and physician workforce implications. Production of primary care physicians and general surgeons was assessed by retrospective analysis of the 2009 American Medical Association Masterfile, which includes physicians' training institution, residency specialty, and year of completion for up to six training experiences. The authors measured production rates for each institution based on physicians completing their first residency during 2005-2007 in family or internal medicine, pediatrics, or general surgery. They then reassessed rates to account for those who completed additional training. They compared these rates with proposed expansion eligibility thresholds and current workforce needs. Of 116,004 physicians completing their first residency, 54,245 (46.8%) were in primary care and general surgery. Of 683 training institutions, 586 met the 25% threshold for expansion eligibility. At two to four years out, only 29,963 physicians (25.8%) remained in primary care or general surgery, and 135 institutions lost eligibility. A 35% threshold eliminated 314 institutions collectively training 93,774 residents (80.8%). Residency expansion thresholds that do not account for production at least two to four years after completion of first residency overestimate eligibility. The overall primary care production rate from GME will not sustain the current physician workforce composition. Copyright © by the Association of American medical Colleges.

  13. Efficiency and productivity terms for water management: A matter of contextual relativism versus general absolutism

    NARCIS (Netherlands)

    Halsema, van G.E.; Vincent, L.F.

    2012-01-01

    Growing water scarcity and increasing demands for agricultural products generate much debate about improving the agricultural sector's water use efficiency and productivity. Agricultural engineering traditions feed this debate with notions such as agricultural yield gaps and low water use

  14. Overall requirements for an advanced underground coal extraction system. [environment effects, miner health and safety, production cost, and coal conservation

    Science.gov (United States)

    Goldsmith, M.; Lavin, M. L.

    1980-01-01

    Underground mining systems suitable for coal seams expoitable in the year 2000 are examined with particular relevance to the resources of Central Appalachia. Requirements for such systems may be summarized as follows: (1) production cost; (2)miner safety; (3) miner health; (4) environmental impact; and (5) coal conservation. No significant trade offs between production cost and other performance indices were found.

  15. 10 CFR 32.22 - Self-luminous products containing tritium, krypton-85 or promethium-147: Requirements for license...

    Science.gov (United States)

    2010-01-01

    ... 10 Energy 1 2010-01-01 2010-01-01 false Self-luminous products containing tritium, krypton-85 or... containing tritium, krypton-85 or promethium-147: Requirements for license to manufacture, process, produce... self-luminous products containing tritium, krypton-85, or promethium-147, or to initially transfer such...

  16. 21 CFR 610.11 - General safety.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 7 2010-04-01 2010-04-01 false General safety. 610.11 Section 610.11 Food and... GENERAL BIOLOGICAL PRODUCTS STANDARDS General Provisions § 610.11 General safety. A general safety test... for administration to humans. The general safety test is required in addition to other specific tests...

  17. 77 FR 28281 - Withdrawal of Revocation of TSCA Section 4 Testing Requirements for One High Production Volume...

    Science.gov (United States)

    2012-05-14

    ... Withdrawal of Revocation of TSCA Section 4 Testing Requirements for One High Production Volume Chemical...]amino]- (CAS No. 1324-76-1), also known as C.I. Pigment Blue 61. EPA received an adverse comment regarding C.I. Pigment Blue 61. This document withdraws the revocation of testing requirements for C.I...

  18. Potential impact of environmental requirements on petroleum products derived from synthetic crude

    International Nuclear Information System (INIS)

    1997-01-01

    Fuel quality proposals regarding gasoline and diesel fuels were discussed. Strict regulations on air emissions will mean changes in transportation fuel specifications which will ultimately impact on the refining industry. As fuel quality requirements become more stringent, refiners will need to look more closely at increasing the use of Canadian synthetic crude as a refinery feed. The fuel quality specifications with the potentially highest impact for the continued use of synthetic crude are those relating to sulphur, aromatics (including benzene), and olefins in gasoline and sulphur, aromatics and cetane in diesel fuel. Synthetic crude has an advantage in terms of gasoline sulphur content. The FCC feed is at a low enough sulphur level to result in gasoline components that would allow refiners to meet final gasoline sulphur levels of less than 100 ppm. In either case, synthetic middle distillate must be upgraded. Options that face the synthetic crude and refining industries are: (1) synthetic crude producers may install the process equipment needed to upgrade the middle distillate portion of their synthetic crude stream, (2) refiners may install equipment to upgrade just the diesel fuel portion of the middle distillate pool and jet fuel, and (3) a joint effort may be made by the two industries. The National Centre for Upgrading Technology (NCUT) and the Western Research Centre of Natural Resources Canada will continue to assist with research into improved catalysts for hydrotreating of middle distillates, and new lower cost processes for upgrading middle distillates from synthetic and conventional crude oils to meet future product requirements. 5 refs., 1 tab

  19. Nuclear Factor kappa B is required for the production of infectious human herpesvirus 8 virions

    Directory of Open Access Journals (Sweden)

    Negin N Blattman

    2014-04-01

    Full Text Available Human herpesvirus 8 (HHV8 infection leads to potent activation of nuclear factor kappa B (NFB in primary and transformed cells. We used recombinant HHV8 (rKSHV.219 expressing green fluorescent protein under the constitutive cellular promoter elongation factor 2 and red fluorescent protein under an early HHV8 lytic gene promoter T1.1, to monitor replication during infection of human foreskin fibroblasts (HF, noting changes in NFB activity. In primary HF, NFB levels do not affect HHV8 ability to establish infection or maintain latency. Furthermore, there was no effect on the percent of cells undergoing reactivation from latency, and there were similar numbers of released and cell associated HHV8 viral particles following reactivation in the presence of inhibitors. Reactivation of HHV8 in latently infected HF in the presence of NFB inhibitors resulted in production of viral particles that did not efficiently establish infection, due to deficiencies in binding and/or entry into normally permissive cells. Exogenous expression of glycoprotein M, an envelope protein involved in viral binding and entry was able to partially overcome the deficiency induced by NFB inhibitors. Our data indicate that in primary cells, NFB is not required for infection, establishment of latency, or entry into the lytic cycle, but is required for the expression of virion associated genes involved in the initial steps of virion infectivity. These studies suggest that strategies to inhibit NFB may prevent HHV8 spread and should be considered as a potential therapeutic target for preventing HHV8 associated diseases.

  20. Analysis of technology requirements and potential demand for general aviation avionics systems for operation in the 1980's

    Science.gov (United States)

    Cohn, D. M.; Kayser, J. H.; Senko, G. M.; Glenn, D. R.

    1974-01-01

    Avionics systems are identified which promise to reduce economic constraints and provide significant improvements in performance, operational capability and utility for general aviation aircraft in the 1980's.

  1. Similarities of Water-soluble Vitamin Components among Non-prescription Pharmaceutical Vitamin Products Generally Available on the Domestic Market.

    Science.gov (United States)

    Suzuki, Keiichiro; Kojina, Moeko; Aiba, Tetsuya

    2017-01-01

    Similarities among non-prescription pharmaceutical vitamin products generally available in community pharmacies were examined based on their vitamin components, and a chart was constructed to differentiate products to assist in appropriate product choice. In the analysis of the similarities, two hundred and seventy-six data entries on vitamin products were extracted from the database on the package inserts of the pharmaceutical products provided by the Pharmaceuticals and Medical Devices Agency, and they were reviewed for the amounts of vitamins they contained, in which the B vitamins, or vitamin B 1 , B 2 , B 6 , B 12 , and niacin, were considered as well as vitamins C and E. Pantothenic acid and L-Cysteine that are frequently used in combination with those vitamins are also taken into consideration. The data entries were then processed by classical multi-dimensional scaling to evaluate the inter-product similarities. As a result, it was shown that the products categorized as pharmaceutical nutrients and tonics containing vitamins (NTcV) are similar to one another, reflecting the fact that they are less characteristic regarding their vitamin components. As for the products in other categories, they were generally found to be featured for their unique content of vitamin components, and thereby, each category includes products with a wide range of variation. It was also indicated that some products categorized as vitamin B 1 , B 2 , and C products are less distinguishable from those categorized as NTcV. These findings will assist pharmacists to decide on an appropriate product for a customer following consultation.

  2. Grading of Requirements for Radioactive Waste Activities in Nuclear Research Reactors: Radioisotope Production Facilities

    International Nuclear Information System (INIS)

    Tawfik, Y.E.

    2017-01-01

    A graded approach is applicable in all stages of the life time of a research reactor. During the life time of a research reactor, any grading performed should not, in any manner, affect safety functions and operational limits and conditions are preserved, so that there are no undue radiological hazards to workers, public or environment. The grading of activities should be based on safety analyses, and regulatory requirements. Other elements to be considered in grading are the complexity and the maturity of the technology, operating experience associated with the activities and the stage in the life time of the facility. In order to ensure that proper and a de quate provision is made for the safety implications associated with the management and disposal of radioactive waste, the waste is characterized and classified. The general scheme for classifying radioactive waste as presented in the current study is based on considerations of long term safety, and thus, by implication, disposal of the waste. This classification provides a starting point for the grading of activities associated with the packaging and disposal of radioactive waste

  3. The Impact of Productivity Increasing in Indonesian Maritim Sector: General Equilibrium Analysis

    Directory of Open Access Journals (Sweden)

    Widyastutik Widyastutik

    2016-09-01

    Full Text Available The increase in productivity in the maritime sector will realize the maritime sector as a prime mover. This study aims to analyze the impact of the maritime sector productivity improvement on the performance of the economy. This research simulates increased productivity in the maritime sector (consisting of the fisheries, oil, gas sub-sector and marine transport services sector using the Global Trade Analysis Project (GTAP version 8. Simulation analysis showed an increase in productivity in the maritime sector has a positive impact on welfare, real GDP, and trade balance of Indonesia. However, the impact of the increase in productivity is not followed by an increase in output in all sectors. This indicates that if the increase in productivity occurs only in the maritime sector alone without being followed by an increase in productivity in other sectors, the sectoral performance is not optimal.DOI: 10.15408/sjie.v5i2.3403

  4. 9 CFR 381.148 - Processing and handling requirements for frozen poultry products.

    Science.gov (United States)

    2010-01-01

    ... for frozen poultry products. 381.148 Section 381.148 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE AGENCY ORGANIZATION AND TERMINOLOGY; MANDATORY MEAT AND POULTRY PRODUCTS INSPECTION AND VOLUNTARY INSPECTION AND CERTIFICATION POULTRY PRODUCTS INSPECTION REGULATIONS...

  5. Food and nutritional security requires adequate protein as well as energy, delivered from whole-year crop production

    DEFF Research Database (Denmark)

    Coles, Graeme D; Wratten, Stephen D; Porter, John Roy

    2016-01-01

    Human food security requires the production of sufficient quantities of both high-quality protein and dietary energy. In a series of case-studies from New Zealand, we show that while production of food ingredients from crops on arable land can meet human dietary energy requirements effectively...... and nutritional security will largely be an outcome of national or regional agroeconomies addressing their own food needs. We hope that our model will be used for similar analyses of food production systems in other countries, agroecological zones and economies....

  6. Governmental, Legal and Regulatory Framework for Safety. General Safety Requirements. Part 1 (French Edition); Cadre gouvernemental, legislatif et reglementaire de la surete. Prescriptions generales de surete. Partie 1

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2010-11-15

    The objective of this publication is to establish requirements in respect of the governmental, legal and regulatory framework for safety. It covers the essential aspects of the framework for establishing a regulatory body and taking other actions necessary to ensure the effective regulatory control of facilities and activities utilized for peaceful purposes. Other responsibilities and functions, such as liaison within the global safety regime and on support services for safety (including radiation protection), emergency preparedness and response, nuclear security, and the State system of accounting for and control of nuclear material, are also covered.

  7. Governmental, Legal and Regulatory Framework for Safety. General Safety Requirements. Part 1 (Spanish Edition); Marco gubernamental, juridico y regulador para la seguridad. Requisitos de Seguridad Generales. Parte 1

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2010-11-15

    The objective of this publication is to establish requirements in respect of the governmental, legal and regulatory framework for safety. It covers the essential aspects of the framework for establishing a regulatory body and taking other actions necessary to ensure the effective regulatory control of facilities and activities utilized for peaceful purposes. Other responsibilities and functions, such as liaison within the global safety regime and on support services for safety (including radiation protection), emergency preparedness and response, nuclear security, and the State system of accounting for and control of nuclear material, are also covered.

  8. Analytical challenges and regulatory requirements for nasal drug products in europe and the u.s.

    Science.gov (United States)

    Trows, Sabrina; Wuchner, Klaus; Spycher, Rene; Steckel, Hartwig

    2014-04-11

    Nasal drug delivery can be assessed by a variety of means and regulatory agencies, e.g., the Food and Drug Administration (FDA) and the European Medicines Agency (EMA) have published a set of guidelines and regulations proposing in vitro test methods for the characterization of nasal drug products. This article gives a summary of the FDA and EMA requirements regarding the determination of droplet size distribution (DSD), plume geometry, spray pattern and shot weights of solution nasal sprays and discusses the analytical challenges that can occur when performing these measurements. In order to support findings from the literature, studies were performed using a standard nasal spray pump and aqueous model formulations. The aim was to identify possible method-, device- and formulation-dependent influencing factors. The literature review, as well as the results from the studies show that DSD, plume geometry and spray pattern are influenced by, e.g., the viscosity of the solution, the design of the device and the actuation parameters, particularly the stroke length, actuation velocity and actuation force. The dominant factor influencing shot weights, however, is the adjustment of the actuation parameters, especially stroke length and actuation velocity. Consequently, for routine measurements assuring, e.g., the quality of a solution nasal spray or, for in vitro bioequivalence studies, the critical parameters, have to be identified and considered in method development in order to obtain reproducible and reliable results.

  9. General decoupling procedure for expectation values of four-operator products in electron–phonon quantum kinetics

    International Nuclear Information System (INIS)

    Teeny, Nicolas; Fähnle, Manfred

    2013-01-01

    In the density-matrix formalism of electron–phonon quantum kinetics, the hierarchy of infinitely many coupled equations of motion for the expectation values of products of electron and phonon creation and annihilation operators of arbitrary order is usually terminated on the level of the equations of motion for the expectation values of three-operator products by using decoupling procedures for the four-operator products occurring in these equations. In the literature, decoupling procedures are discussed for special types of electron and phonon states. In the present paper, generalized decoupling procedures are derived for arbitrary electron and phonon states. (paper)

  10. Manufacturing cost analysis of a parabolic dish concentrator (General Electric design) for solar thermal electric power systems in selected production volumes

    Science.gov (United States)

    1981-01-01

    The manufacturing cost of a General Electric 12 meter diameter concentrator was estimated. This parabolic dish concentrator for solar thermal system was costed in annual production volumes of 100 - 1,000 - 5,000 - 10,000 - 50,000 100,000 - 400,000 and 1,000,000 units. Presented for each volume are the costs of direct labor, material, burden, tooling, capital equipment and buildings. Also presented is the direct labor personnel and factory space requirements. All costs are based on early 1981 economics.

  11. Time horizons and electricity futures: An application of Nicholas Georgescu-Roegen's general theory of economic production

    Energy Technology Data Exchange (ETDEWEB)

    Farrell, Katharine N. [Department of Economics, Helmholtz Centre for Environmental Research - UFZ, Permoserstr. 15, 04318 Leipzig (Germany); Gibson Institute for Land, Food and Environment, Queen' s University of Belfast, Northern Ireland (United Kingdom); Mayumi, Kozo [Faculty of Integrated Arts and Sciences, The University of Tokushima (Japan)

    2009-03-15

    This paper reports theoretical economic production work and uses electricity futures trading to illustrate its argument. The focus is relationships between time, production and tradition both in Nicholas Georgescu-Roegen's analytical representation of the production process (i.e., flow/fund model) and in his dialectical scheme dealing with the evolutionary changes in the economic process. Our main arguments are (1) the flow/fund model is designed to be employed in conjunction with attention to how the boundaries of a given process are determined and (2) process boundaries are dialectical distinctions - between process and not-process - that are strongly related to time and tradition. We propose that Georgescu-Roegen's The Entropy Law and the Economic Process is best understood as the elaboration of a general theory of economic production and we developed two conceptual tools (time {open_square} and meta-funds), both of which are related to the dialectical distinction between process and not-process, which we use to operationalise this general theory. Finally, we demonstrate that, although trading in electricity futures is surprising if one uses a stock/flow vs services distinction (because electricity supply is classed as a service) it appears perfectly logical under Georgescu-Roegen's general theory: shortening time horizons, combined with a shift in the relationship between raw fuel supplies and power production procedures, lead to a shift in the status of electricity supply, from fund to flow. (author)

  12. 75 FR 73861 - Change in Rates and Classes of General Applicability for Competitive Products

    Science.gov (United States)

    2010-11-29

    ... percent for parcels picked up at a return Network Distribution Center (RNDC) and 8.0 percent for parcels... Part III Postal Service Change in Rates and Classes of General Applicability for Competitive...; [[Page 73862

  13. 24 CFR 200.944 - Supplementary specific requirements under the HUD building product standards and certification...

    Science.gov (United States)

    2010-04-01

    ... under the HUD building product standards and certification program for plywood and other performance... product standards and certification program for plywood and other performance rated wood-based structural... building product certification program. In the case of plywood and wood-based structural-use panels...

  14. Endogenous production of fibronectin is required for self-renewal of cultured mouse embryonic stem cells.

    Science.gov (United States)

    Hunt, Geoffrey C; Singh, Purva; Schwarzbauer, Jean E

    2012-09-10

    Pluripotent cells are attached to the extracellular matrix (ECM) as they make cell fate decisions within the stem cell niche. Here we show that the ubiquitous ECM protein fibronectin is required for self-renewal decisions by cultured mouse embryonic stem (mES) cells. Undifferentiated mES cells produce fibronectin and assemble a fibrillar matrix. Increasing the level of substrate fibronectin increased cell spreading and integrin receptor signaling through focal adhesion kinase, while concomitantly inducing the loss of Nanog and Oct4 self-renewal markers. Conversely, reducing fibronectin production by mES cells growing on a feeder-free gelatin substrate caused loss of cell adhesion, decreased integrin signaling, and decreased expression of self-renewal markers. These effects were reversed by providing the cells with exogenous fibronectin, thereby restoring adhesion to the gelatin substrate. Interestingly, mES cells do not adhere directly to the gelatin substrate, but rather adhere indirectly through gelatin-bound fibronectin, which facilitates self-renewal via its effects on cell adhesion. These results provide new insights into the mechanism of regulation of self-renewal by growth on a gelatin-coated surface. The effects of increasing or decreasing fibronectin levels show that self-renewal depends on an intermediate level of cell-fibronectin interactions. By providing cell adhesive signals that can act with other self-renewal factors to maintain mES cell pluripotency, fibronectin is therefore a necessary component of the self-renewal signaling pathway in culture. Copyright © 2012 Elsevier Inc. All rights reserved.

  15. 17 CFR 147.3 - General requirement of open meetings; grounds upon which meetings may be closed.

    Science.gov (United States)

    2010-04-01

    ..., creed, national origin, ancestry, religion or sex. Except as provided in paragraph (b) of this section... Freedom of Information Act, as amended, 5 U.S.C. 552), provided that such statute (i) requires that the...

  16. 75 FR 22586 - Energy Conservation Program for Consumer Products: Notice of Petition for Waiver of General...

    Science.gov (United States)

    2010-04-29

    ... Appliances Corp. (Bosch-Siemens Hausgerate GmbH), Electrolux Home Products, Equator, Fisher & Paykel... Corp. filed and was granted its waiver petition, \\2\\ as was Electrolux \\3\\ and Samsung.\\4\\ \\1\\ FR Vol...

  17. Productive infection of human immunodeficiency virus type 1 in dendritic cells requires fusion-mediated viral entry

    International Nuclear Information System (INIS)

    Janas, Alicia M.; Dong, Chunsheng; Wang Jianhua; Wu Li

    2008-01-01

    Human immunodeficiency virus type 1 (HIV-1) enters dendritic cells (DCs) through endocytosis and viral receptor-mediated fusion. Although endocytosis-mediated HIV-1 entry can generate productive infection in certain cell types, including human monocyte-derived macrophages, productive HIV-1 infection in DCs appears to be dependent on fusion-mediated viral entry. It remains to be defined whether endocytosed HIV-1 in DCs can initiate productive infection. Using HIV-1 infection and cellular fractionation assays to measure productive viral infection and entry, here we show that HIV-1 enters monocyte-derived DCs predominately through endocytosis; however, endocytosed HIV-1 cannot initiate productive HIV-1 infection in DCs. In contrast, productive HIV-1 infection in DCs requires fusion-mediated viral entry. Together, these results provide functional evidence in understanding HIV-1 cis-infection of DCs, suggesting that different pathways of HIV-1 entry into DCs determine the outcome of viral infection

  18. Evaluation of aqueous tear production in dogs after general anaesthesia with medetomidine-propofol-carprofen-halothane.

    Science.gov (United States)

    Komnenou, A T H; Kazakos, G M; Savvas, I; Thomas, A L N

    2013-08-10

    The influence of an anaesthetic protocol, which included medetomidine, propofol, carprofen and halothane on tear production in the dog. There are no previous studies on the effects of this combination on tear production in dogs or in any other species. The present study included 39 dogs, which underwent non-ophthalmic surgery in our clinic. Preanaesthetically, all dogs had normal tear production (18.62±3.65 mm/minute) as this was recorded with Schirmer tear test I (STT I) and the ophthalmologic examination did not reveal anything abnormal. Tear production readings were recorded before the administration of premedication, at the end of anaesthesia, one hour and two hours postanaesthesia. No reverse agent was administrated. At the end of anaesthesia (right eye (oculus dexter, OD) P<0.0005, left eye (oculus sinister, OS) P<0.0005), as well as one hour postanaesthesia (OD P=0.020, OS P=0.001) there was a statistically significant reduction in tear production, which returned to normal values two hours postanaesthesia, regardless of the duration of the operation. This anaesthetic combination resulted in a decrease in tear production and, therefore, the use of tear substitute treatment in dogs undergoing anaesthesia with this protocol (combination) from the time the sedative is given until at least two hours after the end of anaesthesia is highly recommended.

  19. 21 CFR 211.132 - Tamper-evident packaging requirements for over-the-counter (OTC) human drug products.

    Science.gov (United States)

    2010-04-01

    ..., DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) DRUGS: GENERAL CURRENT GOOD MANUFACTURING PRACTICE FOR...; (ii) Is prominently placed on the package; and (iii) Is so placed that it will be unaffected if the... product or, if the petition seeks an exemption for a drug class, the name of the drug class, and a list of...

  20. The Environmental Quality – Requirements for the Pro-active Approach of Production Enterprises

    Directory of Open Access Journals (Sweden)

    Beáta Stehlíková

    2005-11-01

    Full Text Available The interrelationship and cooperation of the Quality Management System, the Environmental Management System QMS, and Environmental Management System EMS in production enterprises has a very important impact to their performance. The synergic effect of two systems {QMS + EMS} created the so called POEMS Product and the Process Oriented Environmental Management System functioning for the benefit of the Company Profit, Customer Satisfaction, Product Competition, Environment and the Social Responsibility.