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Sample records for problems arise primarily

  1. Multi-objective convex programming problem arising in multivariate ...

    African Journals Online (AJOL)

    user

    Multi-objective convex programming problem arising in ... However, although the consideration of multiple objectives may seem a novel concept, virtually any nontrivial ..... Solving multiobjective programming problems by discrete optimization.

  2. Using packaged software for solving two differential equation problems that arise in plasma physics

    International Nuclear Information System (INIS)

    Gaffney, P.W.

    1980-01-01

    Experience in using packaged numerical software for solving two related problems that arise in Plasma physics is described. These problems are (i) the solution of the reduced resistive MHD equations and (ii) the solution of the Grad-Shafranov equation

  3. Variational problems arising in classical mechanics and nonlinear elasticity

    International Nuclear Information System (INIS)

    Spencer, P.

    1999-01-01

    In this thesis we consider two different classes of variational problems. First, one-dimensional problems arising from classical mechanics where the problem is to determine whether there is a unique function η 0 (x) which minimises the energy functional of the form I(η) = ∫ a b L(x,η(x), η'(x)) dx. We will investigate uniqueness by making a change of dependent and independent variables and showing that for a class of integrands L with a particular kind of scaling invariance the resulting integrand is completely convex. The change of variables arises by applying results from Lie group theory as applied in the study of differential equations and this work is motivated by [60] and [68]. Second, the problem of minimising energy functionals of the form E(u) = ∫ A W(∇u(x)) dx in the case of a nonlinear elastic body occupying an annular region A contains R 2 with u : A-bar → A-bar. This work is motivated by [57] (in particular the example of paragraph 4). We will consider rotationally symmetric deformations satisfying prescribed boundary conditions. We will show the existence of minimisers for stored energy functions of the form W(F) = g-tilde(vertical bar-F-vertical bar, det(F)) in a class of general rotationally symmetric deformations of a compressible annulus and for stored energy functions of the form W(F) = g-bar(vertical bar-F-vertical bar) in a class of rotationally symmetric deformations of an incompressible annulus. We will also show that in each case the minimisers are solutions of the full equilibrium equations. A model problem will be considered where the energy functional is the Dirichlet integral and it will be shown that the rotationally symmetric solution obtained is a minimiser among admissible non-rotationally symmetric deformations. In the case of an incompressible annulus, we will consider the Dirichlet integral as the energy functional and show that the rotationally symmetric equilibrium solutions in this case are weak local minimisers in

  4. New homotopy analysis transform method for solving the discontinued problems arising in nanotechnology

    International Nuclear Information System (INIS)

    Khader, M. M.; Kumar, Sunil; Abbasbandy, S.

    2013-01-01

    We present a new reliable analytical study for solving the discontinued problems arising in nanotechnology. Such problems are presented as nonlinear differential—difference equations. The proposed method is based on the Laplace transform with the homotopy analysis method (HAM). This method is a powerful tool for solving a large amount of problems. This technique provides a series of functions which may converge to the exact solution of the problem. A good agreement between the obtained solution and some well-known results is obtained

  5. Single string planning problem arising in liner shipping industries: A heuristic approach

    DEFF Research Database (Denmark)

    Gelareh, Shahin; Neamatian Monemi, Rahimeh; Mahey, Philippe

    2013-01-01

    We propose an efficient heuristic approach for solving instances of the Single String Planning Problem (SSPP) arising in the liner shipping industry. In the SSPP a Liner Service Provider (LSP) only revises one of its many operational strings, and it is assumed that the other strings are unchangea...

  6. Radioisotopes: problems of responsibility arising from medicine

    International Nuclear Information System (INIS)

    Dupon, Michel.

    1978-09-01

    Radioisotopes have brought about great progress in the battle against illnesses of mainly tumoral origin, whether in diagnosis (nuclear medicine) or in treatment (medical radiotherapy). They are important enough therefore to warrant investigation. Such a study is attempted here, with special emphasis, at a time when medical responsibility proceedings are being taken more and more often on the medicolegal problems arising from their medical use. It is hoped that this study on medical responsibility in the use of radioisotopes will have shown: that the use of radioisotopes for either diagnosis or therapy constitutes a major banch of medicine; that this importance implies an awareness by the practitioner of a vast responsibility, especially in law where legislation to ensure protection as strict as in the field of ionizing radiations is lacking. The civil responsibility of doctors who use radioisotopes remains to be defined, since for want of adequate jurisprudence we are reduced to hypotheses based on general principles [fr

  7. Nuclear waste management and problems arising from constitutional law

    International Nuclear Information System (INIS)

    Rauschning, D.

    1983-01-01

    The author discusses the problems arising in the field of nuclear waste management on account of the constitutional law. Especially the difficulties emanating from the conflict between the provisions of section 9a of the Atomic Energy Act and the provisions of constitutional law are dealt with in detail, referring to the monography of H. Hofmann, 'legal aspects of nuclear waste management'. The author comes to the conclusion that the reqquirements laid down in section 9a-9c of the Atomic Energy Act are in agreement with the Basic law. There is, he says, no unreasonable risk for future generations, as the provisions of the nuclear law provide for sufficient safety of sites and equipment selected for the final storage of nuclear waste, ensuring that radioactive leakage is excluded over long periods of time. In the second part of his lecture, the author discusses the problem of competency and delegation of authority with regard to the reprocessing of radioactive waste. (BW) [de

  8. On some nonlinear problems arising in the physics of ionized gases

    International Nuclear Information System (INIS)

    Hilhorst-Goldman, D.

    1981-01-01

    The author reports results obtained by rigorous analysis of a nonlinear differential equation for the electron density nsub(e) in a specific type of electrical discharge. The problem is essentially two-dimensional. She discusses in particular the escape of electrons to infinity above a critical temperature and the boundary layer exhibited by nsub(e) near zero temperature. A singular boundary value problem arising in a pre-breakdown gas discharge is discussed. A Coulomb gas is considered in a special experimental situation: the pre-breakdown gas discharge between two electrodes. The equation for the negative charge density can be formulated as a nonlinear parabolic equation degenerate at the origin. The existence and uniqueness of the solution are proved as well as the asymptotic stability of its unique steady state. Some results are also given about the rate of convergence. The variational characterisation of the limit solution of a singular perturbation problem and variational analysis of a perturbed free boundary problem are considered. (Auth./C.F.)

  9. A simultaneous facility location and vehicle routing problem arising in health care logistics in the Netherlands

    NARCIS (Netherlands)

    Veenstra, Marjolein; Roodbergen, Kees Jan; Coelho, Leandro C.; Zhu, Stuart X.

    2018-01-01

    This paper introduces a simultaneous facility location and vehicle routing problem that arises in health care logistics in the Netherlands. In this problem, the delivery of medication from a local pharmacy can occur via lockers, from where patients that are within the coverage distance of a locker

  10. Iterative solution of a nonlinear system arising in phase change problems

    International Nuclear Information System (INIS)

    Williams, M.A.

    1987-01-01

    We consider several iterative methods for solving the nonlinear system arising from an enthalpy formulation of a phase change problem. We present the formulation of the problem. Implicit discretization of the governing equations results in a mildly nonlinear system at each time step. We discuss solving this system using Jacobi, Gauss-Seidel, and SOR iterations and a new modified preconditioned conjugate gradient (MPCG) algorithm. The new MPCG algorithm and its properties are discussed in detail. Numerical results are presented comparing the performance of the SOR algorithm and the MPCG algorithm with 1-step SSOR preconditioning. The MPCG algorithm exhibits a superlinear rate of convergence. The SOR algorithm exhibits a linear rate of convergence. Thus, the MPCG algorithm requires fewer iterations to converge than the SOR algorithm. However in most cases, the SOR algorithm requires less total computation time than the MPCG algorithm. Hence, the SOR algorithm appears to be more appropriate for the class of problems considered. 27 refs., 11 figs

  11. Quenching rate for a nonlocal problem arising in the micro-electro mechanical system

    Science.gov (United States)

    Guo, Jong-Shenq; Hu, Bei

    2018-03-01

    In this paper, we study the quenching rate of the solution for a nonlocal parabolic problem which arises in the study of the micro-electro mechanical system. This question is equivalent to the stabilization of the solution to the transformed problem in self-similar variables. First, some a priori estimates are provided. In order to construct a Lyapunov function, due to the lack of time monotonicity property, we then derive some very useful and challenging estimates by a delicate analysis. Finally, with this Lyapunov function, we prove that the quenching rate is self-similar which is the same as the problem without the nonlocal term, except the constant limit depends on the solution itself.

  12. A Multi-Depot Two-Echelon Vehicle Routing Problem with Delivery Options Arising in the Last Mile Distribution

    NARCIS (Netherlands)

    Zhou, Lin; Baldacci, Roberto; Vigo, Daniele; Wang, Xu

    2018-01-01

    In this paper, we introduce a new city logistics problem arising in the last mile distribution of e-commerce. The problem involves two levels of routing problems. The first requires a design of the routes for a vehicle fleet located at the depots to transport the customer demands to a subset of the

  13. Distribution-valued weak solutions to a parabolic problem arising in financial mathematics

    Directory of Open Access Journals (Sweden)

    Michael Eydenberg

    2009-07-01

    Full Text Available We study distribution-valued solutions to a parabolic problem that arises from a model of the Black-Scholes equation in option pricing. We give a minor generalization of known existence and uniqueness results for solutions in bounded domains $Omega subset mathbb{R}^{n+1}$ to give existence of solutions for certain classes of distributions $fin mathcal{D}'(Omega$. We also study growth conditions for smooth solutions of certain parabolic equations on $mathbb{R}^nimes (0,T$ that have initial values in the space of distributions.

  14. Calculation of Rayleigh type sums for zeros of the equation arising in spectral problem

    Science.gov (United States)

    Kostin, A. B.; Sherstyukov, V. B.

    2017-12-01

    For zeros of the equation (arising in the oblique derivative problem) μ J n ‧ ( μ ) cos α + i n J n ( μ ) sin α = 0 , μ ∈ ℂ , with parameters n ∈ ℤ, α ∈ [-π/2, π/2] and the Bessel function Jn (μ) special summation relationships are proved. The obtained results are consistent with the theory of well-known Rayleigh sums calculating by zeros of the Bessel function.

  15. Kapteyn series arising in radiation problems

    International Nuclear Information System (INIS)

    Lerche, I; Tautz, R C

    2008-01-01

    In discussing radiation from multiple point charges or magnetic dipoles, moving in circles or ellipses, a variety of Kapteyn series of the second kind arises. Some of the series have been known in closed form for a hundred years or more, others appear not to be available to analytic persuasion. This paper shows how 12 such generic series can be developed to produce either closed analytic expressions or integrals that are not analytically tractable. In addition, the method presented here may be of benefit when one has other Kapteyn series of the second kind to consider, thereby providing an additional reason to consider such series anew

  16. An adaptive large neighborhood search heuristic for Two-Echelon Vehicle Routing Problems arising in city logistics

    Science.gov (United States)

    Hemmelmayr, Vera C.; Cordeau, Jean-François; Crainic, Teodor Gabriel

    2012-01-01

    In this paper, we propose an adaptive large neighborhood search heuristic for the Two-Echelon Vehicle Routing Problem (2E-VRP) and the Location Routing Problem (LRP). The 2E-VRP arises in two-level transportation systems such as those encountered in the context of city logistics. In such systems, freight arrives at a major terminal and is shipped through intermediate satellite facilities to the final customers. The LRP can be seen as a special case of the 2E-VRP in which vehicle routing is performed only at the second level. We have developed new neighborhood search operators by exploiting the structure of the two problem classes considered and have also adapted existing operators from the literature. The operators are used in a hierarchical scheme reflecting the multi-level nature of the problem. Computational experiments conducted on several sets of instances from the literature show that our algorithm outperforms existing solution methods for the 2E-VRP and achieves excellent results on the LRP. PMID:23483764

  17. An adaptive large neighborhood search heuristic for Two-Echelon Vehicle Routing Problems arising in city logistics.

    Science.gov (United States)

    Hemmelmayr, Vera C; Cordeau, Jean-François; Crainic, Teodor Gabriel

    2012-12-01

    In this paper, we propose an adaptive large neighborhood search heuristic for the Two-Echelon Vehicle Routing Problem (2E-VRP) and the Location Routing Problem (LRP). The 2E-VRP arises in two-level transportation systems such as those encountered in the context of city logistics. In such systems, freight arrives at a major terminal and is shipped through intermediate satellite facilities to the final customers. The LRP can be seen as a special case of the 2E-VRP in which vehicle routing is performed only at the second level. We have developed new neighborhood search operators by exploiting the structure of the two problem classes considered and have also adapted existing operators from the literature. The operators are used in a hierarchical scheme reflecting the multi-level nature of the problem. Computational experiments conducted on several sets of instances from the literature show that our algorithm outperforms existing solution methods for the 2E-VRP and achieves excellent results on the LRP.

  18. The global warming problem

    International Nuclear Information System (INIS)

    Anon.

    1990-01-01

    In this chapter, a discussion is presented of the global warming problem and activities contributing to the formation of acid rain, urban smog and to the depletion of the ozone layer. Globally, about two-thirds of anthropogenic carbon dioxide emissions arise from fossil-fuel burning; the rest arise primarily from deforestation. Chlorofluorocarbons are the second largest contributor to global warming, accounting for about 20% of the total. The third largest contributor is methane, followed by ozone and nitrous oxide. A study of current activities in the US that contribute to global warming shows the following: electric power plants account for about 33% of carbon dioxide emissions; motor vehicles, planes and ships (31%); industrial plants (24%); commercial and residential buildings (11%)

  19. A parallel algorithm for solving linear equations arising from one-dimensional network problems

    International Nuclear Information System (INIS)

    Mesina, G.L.

    1991-01-01

    One-dimensional (1-D) network problems, such as those arising from 1- D fluid simulations and electrical circuitry, produce systems of sparse linear equations which are nearly tridiagonal and contain a few non-zero entries outside the tridiagonal. Most direct solution techniques for such problems either do not take advantage of the special structure of the matrix or do not fully utilize parallel computer architectures. We describe a new parallel direct linear equation solution algorithm, called TRBR, which is especially designed to take advantage of this structure on MIMD shared memory machines. The new method belongs to a family of methods which split the coefficient matrix into the sum of a tridiagonal matrix T and a matrix comprised of the remaining coefficients R. Efficient tridiagonal methods are used to algebraically simplify the linear system. A smaller auxiliary subsystem is created and solved and its solution is used to calculate the solution of the original system. The newly devised BR method solves the subsystem. The serial and parallel operation counts are given for the new method and related earlier methods. TRBR is shown to have the smallest operation count in this class of direct methods. Numerical results are given. Although the algorithm is designed for one-dimensional networks, it has been applied successfully to three-dimensional problems as well. 20 refs., 2 figs., 4 tabs

  20. On the Uniqueness of Solutions of a Nonlinear Elliptic Problem Arising in the Confinement of a Plasma in a Stellarator Device

    International Nuclear Information System (INIS)

    Diaz, J. I.; Galiano, G.; Padial, J. F.

    1999-01-01

    We study the uniqueness of solutions of a semilinear elliptic problem obtained from an inverse formulation when the nonlinear terms of the equation are prescribed in a general class of real functions. The inverse problem arises in the modeling of the magnetic confinement of a plasma in a Stellarator device. The uniqueness proof relies on an L ∞ -estimate on the solution of an auxiliary nonlocal problem formulated in terms of the relative rearrangement of a datum with respect to the solution

  1. Projected regression method for solving Fredholm integral equations arising in the analytic continuation problem of quantum physics

    International Nuclear Information System (INIS)

    Arsenault, Louis-François; Millis, Andrew J; Neuberg, Richard; Hannah, Lauren A

    2017-01-01

    We present a supervised machine learning approach to the inversion of Fredholm integrals of the first kind as they arise, for example, in the analytic continuation problem of quantum many-body physics. The approach provides a natural regularization for the ill-conditioned inverse of the Fredholm kernel, as well as an efficient and stable treatment of constraints. The key observation is that the stability of the forward problem permits the construction of a large database of outputs for physically meaningful inputs. Applying machine learning to this database generates a regression function of controlled complexity, which returns approximate solutions for previously unseen inputs; the approximate solutions are then projected onto the subspace of functions satisfying relevant constraints. Under standard error metrics the method performs as well or better than the Maximum Entropy method for low input noise and is substantially more robust to increased input noise. We suggest that the methodology will be similarly effective for other problems involving a formally ill-conditioned inversion of an integral operator, provided that the forward problem can be efficiently solved. (paper)

  2. Boundary Value Problems Arising in Kalman Filtering

    Directory of Open Access Journals (Sweden)

    Sinem Ertürk

    2009-01-01

    Full Text Available The classic Kalman filtering equations for independent and correlated white noises are ordinary differential equations (deterministic or stochastic with the respective initial conditions. Changing the noise processes by taking them to be more realistic wide band noises or delayed white noises creates challenging partial differential equations with initial and boundary conditions. In this paper, we are aimed to give a survey of this connection between Kalman filtering and boundary value problems, bringing them into the attention of mathematicians as well as engineers dealing with Kalman filtering and boundary value problems.

  3. Boundary Value Problems Arising in Kalman Filtering

    Directory of Open Access Journals (Sweden)

    Bashirov Agamirza

    2008-01-01

    Full Text Available The classic Kalman filtering equations for independent and correlated white noises are ordinary differential equations (deterministic or stochastic with the respective initial conditions. Changing the noise processes by taking them to be more realistic wide band noises or delayed white noises creates challenging partial differential equations with initial and boundary conditions. In this paper, we are aimed to give a survey of this connection between Kalman filtering and boundary value problems, bringing them into the attention of mathematicians as well as engineers dealing with Kalman filtering and boundary value problems.

  4. Existence of solutions to boundary value problems arising from the fractional advection dispersion equation

    Directory of Open Access Journals (Sweden)

    Lingju Kong

    2013-04-01

    Full Text Available We study the existence of multiple solutions to the boundary value problem $$displaylines{ frac{d}{dt}Big(frac12{}_0D_t^{-eta}(u'(t+frac12{}_tD_T^{-eta}(u'(t Big+lambda abla F(t,u(t=0,quad tin [0,T],cr u(0=u(T=0, }$$ where $T>0$, $lambda>0$ is a parameter, $0leqeta<1$, ${}_0D_t^{-eta}$ and ${}_tD_T^{-eta}$ are, respectively, the left and right Riemann-Liouville fractional integrals of order $eta$, $F: [0,T]imesmathbb{R}^Nomathbb{R}$ is a given function. Our interest in the above system arises from studying the steady fractional advection dispersion equation. By applying variational methods, we obtain sufficient conditions under which the above equation has at least three solutions. Our results are new even for the special case when $eta=0$. Examples are provided to illustrate the applicability of our results.

  5. Squamous neoplasms arising within tattoos: clinical presentation, histopathology and management.

    Science.gov (United States)

    Junqueira, A L; Wanat, K A; Farah, R S

    2017-08-01

    Tattooing, which involves the placement of ink into the skin, is an ancient decorative technique that has remained popular in modern society. Tattoos have long been known to cause cutaneous reactions, which include the emergence of neoplasms such as keratoacanthoma (KA) and squamous cell carcinoma (SCC) in tattooed areas of the skin. We review the clinical presentations, histology and treatment options for squamous neoplasms, primarily KA and SCC, arising in tattoos. © 2017 British Association of Dermatologists.

  6. Giant Cell Tumor of Rib Arising Anteriorly as a Large Inframammary Mass: A Case Report and Review of the Literature

    Directory of Open Access Journals (Sweden)

    Amit Sharma

    2012-01-01

    posteriorly. The rarity of this tumor poses diagnostic and therapeutic problems for physicians, especially when it is located in the anterior arc of the rib in close proximity to the breasts in female patients. Case Presentation. We report the case of a 32-year-old Asian female with a giant cell tumor of her anterior rib, presenting as a large inframammary mass. Computed tomography showed a tumor arising from the 7th rib anteriorly with marginal sclerosis, cortical destruction, and a soft tissue mass. She was treated with surgical resection, and the defect was reconstructed primarily. The surgical specimen measured 28.0 × 24.0 cm. The microscopic examination showed a large number of multinucleate giant cells scattered over the parenchyma. Patient recovered uneventfully and continues to be recurrence-free six years after surgical resection. Conclusion. We report the largest known case of giant cell tumor arising from the anterior aspect of a rib. We recommend including giant cell tumor in the differential diagnosis of chest wall masses especially in female patients, regardless of the size on clinical examination.

  7. Operator approximant problems arising from quantum theory

    CERN Document Server

    Maher, Philip J

    2017-01-01

    This book offers an account of a number of aspects of operator theory, mainly developed since the 1980s, whose problems have their roots in quantum theory. The research presented is in non-commutative operator approximation theory or, to use Halmos' terminology, in operator approximants. Focusing on the concept of approximants, this self-contained book is suitable for graduate courses.

  8. Occupancy statistics arising from weighted particle rearrangements

    International Nuclear Information System (INIS)

    Huillet, Thierry

    2007-01-01

    The box-occupancy distributions arising from weighted rearrangements of a particle system are investigated. In the grand-canonical ensemble, they are characterized by determinantal joint probability generating functions. For doubly non-negative weight matrices, fractional occupancy statistics, generalizing Fermi-Dirac and Bose-Einstein statistics, can be defined. A spatially extended version of these balls-in-boxes problems is investigated

  9. Nature Inspired Computational Technique for the Numerical Solution of Nonlinear Singular Boundary Value Problems Arising in Physiology

    Directory of Open Access Journals (Sweden)

    Suheel Abdullah Malik

    2014-01-01

    Full Text Available We present a hybrid heuristic computing method for the numerical solution of nonlinear singular boundary value problems arising in physiology. The approximate solution is deduced as a linear combination of some log sigmoid basis functions. A fitness function representing the sum of the mean square error of the given nonlinear ordinary differential equation (ODE and its boundary conditions is formulated. The optimization of the unknown adjustable parameters contained in the fitness function is performed by the hybrid heuristic computation algorithm based on genetic algorithm (GA, interior point algorithm (IPA, and active set algorithm (ASA. The efficiency and the viability of the proposed method are confirmed by solving three examples from physiology. The obtained approximate solutions are found in excellent agreement with the exact solutions as well as some conventional numerical solutions.

  10. Spectral collocation for multiparameter eigenvalue problems arising from separable boundary value problems

    Science.gov (United States)

    Plestenjak, Bor; Gheorghiu, Călin I.; Hochstenbach, Michiel E.

    2015-10-01

    In numerous science and engineering applications a partial differential equation has to be solved on some fairly regular domain that allows the use of the method of separation of variables. In several orthogonal coordinate systems separation of variables applied to the Helmholtz, Laplace, or Schrödinger equation leads to a multiparameter eigenvalue problem (MEP); important cases include Mathieu's system, Lamé's system, and a system of spheroidal wave functions. Although multiparameter approaches are exploited occasionally to solve such equations numerically, MEPs remain less well known, and the variety of available numerical methods is not wide. The classical approach of discretizing the equations using standard finite differences leads to algebraic MEPs with large matrices, which are difficult to solve efficiently. The aim of this paper is to change this perspective. We show that by combining spectral collocation methods and new efficient numerical methods for algebraic MEPs it is possible to solve such problems both very efficiently and accurately. We improve on several previous results available in the literature, and also present a MATLAB toolbox for solving a wide range of problems.

  11. Convex solutions of systems arising from Monge-Ampere equations

    Directory of Open Access Journals (Sweden)

    Haiyan Wang

    2009-10-01

    Full Text Available We establish two criteria for the existence of convex solutions to a boundary value problem for weakly coupled systems arising from the Monge-Ampère equations. We shall use fixed point theorems in a cone.

  12. Assessment by human research ethics committees of potential conflicts of interest arising from pharmaceutical sponsorship of clinical research.

    Science.gov (United States)

    Newcombe, J P; Kerridge, I H

    2007-01-01

    Conflicts of interest arising from pharmaceutical industry sponsorship of clinical research have the potential to bias research outcomes and ultimately prejudice patient care. It is unknown how Australian Human Research Ethics Committees (HREC) assess and manage such conflicts of interest. We aimed to gain an understanding of how HREC approach the problem of potential conflicts of interest arising from pharmaceutical sponsorship of clinical research. We conducted a survey of HREC chairpersons in New South Wales. HREC vary widely in their approaches to conflicts of interest, including in their use of National Health and Medical Research Council guidelines, which were often misinterpreted or overlooked. Many committees rely primarily on researchers disclosing potential conflicts of interest, whereas a majority of HREC use disclosure to research participants as the primary tool for preventing and managing conflicts of interest. Almost no HREC place limitations on researcher relationships with pharmaceutical companies. These findings suggest reluctance on the part of HREC to regulate many potential conflicts of interest between researchers and pharmaceutical sponsors, which may arise from uncertainty regarding the meaning or significance of conflicts of interest in research, from ambiguity surrounding the role of HREC in assessing and managing conflicts of interest in research or from misinterpretation or ignorance of current National Health and Medical Research Council guidelines. Further review of policies and practices in this important area may prove beneficial in safeguarding clinical research and patient care while promoting continuing constructive engagement with the pharmaceutical industry.

  13. Simulating Arctic clouds during Arctic Radiation- IceBridge Sea and Ice Experiment (ARISE)

    Science.gov (United States)

    Bromwich, D. H.; Hines, K. M.; Wang, S. H.

    2015-12-01

    The representation within global and regional models of the extensive low-level cloud cover over polar oceans remains a critical challenge for quantitative studies and forecasts of polar climate. In response, the polar-optimized version of the Weather Research and Forecasting model (Polar WRF) is used to simulate the meteorology, boundary layer, and Arctic clouds during the September-October 2014 Arctic Radiation- IceBridge Sea and Ice Experiment (ARISE) project. Polar WRF was developed with several adjustments to the sea ice thermodynamics in WRF. ARISE was based out of Eielson Air Force Base near Fairbanks, Alaska and included multiple instrumented C-130 aircraft flights over open water and sea ice of the Beaufort Sea. Arctic boundary layer clouds were frequently observed within cold northeasterly flow over the open ocean and ice. Preliminary results indicate these clouds were primarily liquid water, with characteristics differing between open water and sea ice surfaces. Simulated clouds are compared to ARISE observations. Furthermore, Polar WRF simulations are run for the August-September 2008 Arctic Summer Cloud Ocean Study (ASCOS) for comparison to the ARISE. Preliminary analysis shows that simulated low-level water clouds over the sea ice are too extensive during the the second half of the ASCOS field program. Alternatives and improvements to the Polar WRF cloud schemes are considered. The goal is to use the ARISE and ASCOS observations to achieve an improved polar supplement to the WRF code for open water and sea ice that can be provided to the Polar WRF community.

  14. Ethical problems arising from the use of placebo in clinical trials with drugs for migraine. Their analysis by the moral deliberation method.

    Science.gov (United States)

    Frías, J; Pascual, J; Lahuerta, J; Gracia, D; Dal-Ré, R

    2011-03-01

    Migraine is characterised as episodes of headache plus a variety of accompanying symptoms. Its pharmacological control remains unsatisfactory for some patients. The use of placebo in drug clinical trials on migraine commonly leads to numerous ethical uncertainties. The purpose of this paper is to illustrate how the deliberation method helps in analysing the issues and finding solutions to selected ethical problems. Ethical decisions that try to solve conflicts arising from placebo use in clinical trials may be adopted using the moral deliberation method. Thus, the conflict is systematically assessed by identifying the following: Relevant facts; Values in conflict; Duties, or in other words, possible courses of action. Moral duty is following the optimal course of action. To identify this, it is recommended to state extreme courses of action, then intermediate courses of action, and then to proceed to the optimal course(s) of action. In this paper, the application of this method is shown in several conflicting situations arising in two placebo-controlled clinical trials with drugs under development for the prophylaxis and acute treatment of migraine. Copyright © 2010 Sociedad Española de Neurología. Published by Elsevier Espana. All rights reserved.

  15. Associations among everyday stress, critical life events, and sexual problems.

    Science.gov (United States)

    Bodenmann, Guy; Ledermann, Thomas; Blattner, Denise; Galluzzo, Claudia

    2006-07-01

    This study addresses the question of how stress is linked to sexual problems among women and men in close relationships. Psychological symptoms, relationship quality, internal daily stress (i.e., originating within the couple such as conflicts, worry for the partner), external daily stress (i.e., stress arising outside the couple such as job stress, stressful relatives, and so forth), and critical life events were examined with regard to their association with different sexual problems. The results support the hypotheses that (1) there is an incremental effect of stress on sexual problems after controlling for psychological symptoms and relationship quality, and that (2) it is primarily internal daily stress and in some cases critical life events rather than external daily stress that are related to sexual problems, particularly hypoactive sexual desire in women and men, sexual aversion in women, vaginismus in women, and premature ejaculation in men. Our findings indicate that the treatment of these sexual problems should address relationship issues and include a focus on helping individuals improve their stress management skills within their couple relationship.

  16. On a Linear Equation Arising in Isometric Embedding of Torus-like Surface

    Institute of Scientific and Technical Information of China (English)

    Chunhe LI

    2009-01-01

    The solvability of a linear equation and the regularity of the solution are discussed.The equation is arising in a geometric problem which is concerned with the realization of Alexandroff's positive annul in R3.

  17. A non-standard optimal control problem arising in an economics application

    Directory of Open Access Journals (Sweden)

    Alan Zinober

    2013-04-01

    Full Text Available A recent optimal control problem in the area of economics has mathematical properties that do not fall into the standard optimal control problem formulation. In our problem the state value at the final time the state, y(T = z, is free and unknown, and additionally the Lagrangian integrand in the functional is a piecewise constant function of the unknown value y(T. This is not a standard optimal control problem and cannot be solved using Pontryagin's Minimum Principle with the standard boundary conditions at the final time. In the standard problem a free final state y(T yields a necessary boundary condition p(T = 0, where p(t is the costate. Because the integrand is a function of y(T, the new necessary condition is that y(T should be equal to a certain integral that is a continuous function of y(T. We introduce a continuous approximation of the piecewise constant integrand function by using a hyperbolic tangent approach and solve an example using a C++ shooting algorithm with Newton iteration for solving the Two Point Boundary Value Problem (TPBVP. The minimising free value y(T is calculated in an outer loop iteration using the Golden Section or Brent algorithm. Comparative nonlinear programming (NP discrete-time results are also presented.

  18. Problems arising in the evaluation of collective dose commitment

    International Nuclear Information System (INIS)

    Coulon, R.; Beau, P.

    1979-01-01

    In order to apply the concept of optimization it is necessary to evaluate the collective dose commitment for the population as a whole. This is found by summing the dose commitments for the different population groups involved, including persons occupationally exposed and members of the public both locally and globally. The average dose received by each of these groups can vary considerably: for occupational exposure it is about one order of magnitude below the limits, whereas for the general public it is far below, although certain local groups may be subjected to a much higher exposure than the overall average. The question arises, therefore, whether certain groups should not be weighted differently in order to take into account the heterogeneity of the distribution of exposure. As far as the validity of forecast evaluations is concerned, one may assume that for occupational exposure the dose commitment over the whole period of operation of a facility can be estimated fairly accurately. The overall collective dose commitment for the public is relatively insensitive to local variations in the environment and in the public itself but is strongly dependent on long-term developments which cannot at present be forecast. For the evaluation of dose equivalent to the critical group, local variations are of considerable importance and need to be foreseen, which is not always possible. By taking into account a period which includes the annual maximum collective dose equivalent one can make some of these difficulties less severe. (author)

  19. Code of Practice for the Protection of Persons against Ionizing Radiations arising from Medical and Dental Use

    Energy Technology Data Exchange (ETDEWEB)

    1972-01-01

    This Code is a revision of the 1964 Code of Practice for the protection of persons against ionizing radiations arising from medical and dental use. This revised Code (which does not have the force of law) applies to the use of ionizing radiations arising from all forms of medical and dental practice and from allied research involving human subjects. It covers both workers, patients and members of the public. Although the arrangements recommended relate primarily to institutions they should be applied, as far as possible, by all medical and dental practitioners. The Code has been drawn up in the light of the recommendations of the International Commission on Radiological Protection (ICRP) and of the views of the Medical Research Council's Committee on Protection against Ionizing Radiations.

  20. Cost-effective use of minicomputers to solve structural problems

    Science.gov (United States)

    Storaasli, O. O.; Foster, E. P.

    1978-01-01

    Minicomputers are receiving increased use throughout the aerospace industry. Until recently, their use focused primarily on process control and numerically controlled tooling applications, while their exposure to and the opportunity for structural calculations has been limited. With the increased availability of this computer hardware, the question arises as to the feasibility and practicality of carrying out comprehensive structural analysis on a minicomputer. This paper presents results on the potential for using minicomputers for structural analysis by (1) selecting a comprehensive, finite-element structural analysis system in use on large mainframe computers; (2) implementing the system on a minicomputer; and (3) comparing the performance of the minicomputers with that of a large mainframe computer for the solution to a wide range of finite element structural analysis problems.

  1. The pressure equation arising in reservoir simulation. Mathematical properties, numerical methods and upscaling

    Energy Technology Data Exchange (ETDEWEB)

    Nielsen, Bjoern Fredrik

    1997-12-31

    The main purpose of this thesis has been to analyse self-adjoint second order elliptic partial differential equations arising in reservoir simulation. It studies several mathematical and numerical problems for the pressure equation arising in models of fluid flow in porous media. The theoretical results obtained have been illustrated by a series of numerical experiments. The influence of large variations in the mobility tensor upon the solution of the pressure equation is analysed. The performance of numerical methods applied to such problems have been studied. A new upscaling technique for one-phase flow in heterogeneous reservoirs is developed. The stability of the solution of the pressure equation with respect to small perturbations of the mobility tensor is studied. The results are used to develop a new numerical method for a model of fully nonlinear water waves. 158 refs, 39 figs., 12 tabs.

  2. The pressure equation arising in reservoir simulation. Mathematical properties, numerical methods and upscaling

    Energy Technology Data Exchange (ETDEWEB)

    Nielsen, Bjoern Fredrik

    1998-12-31

    The main purpose of this thesis has been to analyse self-adjoint second order elliptic partial differential equations arising in reservoir simulation. It studies several mathematical and numerical problems for the pressure equation arising in models of fluid flow in porous media. The theoretical results obtained have been illustrated by a series of numerical experiments. The influence of large variations in the mobility tensor upon the solution of the pressure equation is analysed. The performance of numerical methods applied to such problems have been studied. A new upscaling technique for one-phase flow in heterogeneous reservoirs is developed. The stability of the solution of the pressure equation with respect to small perturbations of the mobility tensor is studied. The results are used to develop a new numerical method for a model of fully nonlinear water waves. 158 refs, 39 figs., 12 tabs.

  3. Dust in fusion devices-a multi-faceted problem connecting high- and low-temperature plasma physics

    International Nuclear Information System (INIS)

    Winter, J

    2004-01-01

    Small particles with sizes between a few nanometers and a few 10 μm (dust) are formed in fusion devices by plasma-surface interaction processes. Though it is not a major problem today, dust is considered a problem that could arise in future long pulse fusion devices. This is primarily due to its radioactivity and due to its very high chemical reactivity. Dust formation is particularly pronounced when carbonaceous wall materials are used. Dust particles can be transported in the tokamak over significant distances. Radioactivity leads to electrical charging of dust and to its interaction with plasmas and electric fields. This may cause interference with the discharge but may also result in options for particle removal. This paper discusses some of the multi-faceted problems using information both from fusion research and from low-temperature dusty plasma work

  4. On the solution of a rational matrix equation arising in G-networks

    NARCIS (Netherlands)

    B. Meini (Beatrice); T. Nesti (Tommaso)

    2017-01-01

    textabstractWe consider the problem of solving a rational matrix equation arising in the solution of G-networks. We propose and analyze two numerical methods: a fixed point iteration and the Newton–Raphson method. The fixed point iteration is shown to be globally convergent with linear convergence

  5. On the numerical solution of coupled eigenvalue differential equations arising in molecular spectroscopy

    International Nuclear Information System (INIS)

    Friedman, R.S.; Jamieson, M.J.; Preston, S.C.

    1990-01-01

    A method for solving coupled eigenvalue differential equations is given and its relation to an existing technique is shown. Use of the Gram-Schmidt process to overcome the severe instabilities arising in molecular problems is described in detail. (orig.)

  6. Code of Practice for the Protection of Persons against Ionizing Radiations arising from Medical and Dental Use

    International Nuclear Information System (INIS)

    1972-01-01

    This Code is a revision of the 1964 Code of Practice for the protection of persons against ionizing radiations arising from medical and dental use. This revised Code (which does not have the force of law) applies to the use of ionizing radiations arising from all forms of medical and dental practice and from allied research involving human subjects. It covers both workers, patients and members of the public. Although the arrangements recommended relate primarily to institutions they should be applied, as far as possible, by all medical and dental practitioners. The Code has been drawn up in the light of the recommendations of the International Commission on Radiological Protection (ICRP) and of the views of the Medical Research Council's Committee on Protection against Ionizing Radiations. (NEA) [fr

  7. A current value Hamiltonian Approach for Discrete time Optimal Control Problems arising in Economic Growth

    OpenAIRE

    Naz, Rehana

    2018-01-01

    Pontrygin-type maximum principle is extended for the present value Hamiltonian systems and current value Hamiltonian systems of nonlinear difference equations for uniform time step $h$. A new method termed as a discrete time current value Hamiltonian method is established for the construction of first integrals for current value Hamiltonian systems of ordinary difference equations arising in Economic growth theory.

  8. Multiple solutions for inhomogeneous nonlinear elliptic problems arising in astrophyiscs

    Directory of Open Access Journals (Sweden)

    Marco Calahorrano

    2004-04-01

    Full Text Available Using variational methods we prove the existence and multiplicity of solutions for some nonlinear inhomogeneous elliptic problems on a bounded domain in $mathbb{R}^n$, with $ngeq 2$ and a smooth boundary, and when the domain is $mathbb{R}_+^n$

  9. Facilitating Change to a Problem-based Model

    DEFF Research Database (Denmark)

    Kolmos, Anette

    2002-01-01

    The paper presents the barriers which arise during the change process from a traditional educational system to a problem-based educational model.......The paper presents the barriers which arise during the change process from a traditional educational system to a problem-based educational model....

  10. Hausdorff dimension of certain sets arising in Engel expansions

    Science.gov (United States)

    Fang, Lulu; Wu, Min

    2018-05-01

    The present paper is concerned with the Hausdorff dimension of certain sets arising in Engel expansions. In particular, the Hausdorff dimension of the set is completely determined, where A n (x) can stand for the digit, gap and ratio between two consecutive digits in the Engel expansion of x and ϕ is a positive function defined on natural numbers. These results significantly extend the existing results of Galambos’ open problems on the Hausdorff dimension of sets related to the growth rate of digits.

  11. Optimal control of switched systems arising in fermentation processes

    CERN Document Server

    Liu, Chongyang

    2014-01-01

    The book presents, in a systematic manner, the optimal controls under different mathematical models in fermentation processes. Variant mathematical models – i.e., those for multistage systems; switched autonomous systems; time-dependent and state-dependent switched systems; multistage time-delay systems and switched time-delay systems – for fed-batch fermentation processes are proposed and the theories and algorithms of their optimal control problems are studied and discussed. By putting forward novel methods and innovative tools, the book provides a state-of-the-art and comprehensive systematic treatment of optimal control problems arising in fermentation processes. It not only develops nonlinear dynamical system, optimal control theory and optimization algorithms, but can also help to increase productivity and provide valuable reference material on commercial fermentation processes.

  12. MAP estimators and their consistency in Bayesian nonparametric inverse problems

    KAUST Repository

    Dashti, M.; Law, K. J H; Stuart, A. M.; Voss, J.

    2013-01-01

    with examples from an inverse problem for the Navier-Stokes equation, motivated by problems arising in weather forecasting, and from the theory of conditioned diffusions, motivated by problems arising in molecular dynamics. © 2013 IOP Publishing Ltd.

  13. Surprises and pitfalls arising from (pseudo)symmetry

    International Nuclear Information System (INIS)

    Zwart, Peter H.; Grosse-Kunstleve, Ralf W.; Lebedev, Andrey A.; Murshudov, Garib N.; Adams, Paul D.

    2008-01-01

    The presence of pseudosymmetry can cause problems in structure determination and refinement. The relevant background and representative examples are presented. It is not uncommon for protein crystals to crystallize with more than a single molecule per asymmetric unit. When more than a single molecule is present in the asymmetric unit, various pathological situations such as twinning, modulated crystals and pseudo translational or rotational symmetry can arise. The presence of pseudosymmetry can lead to uncertainties about the correct space group, especially in the presence of twinning. The background to certain common pathologies is presented and a new notation for space groups in unusual settings is introduced. The main concepts are illustrated with several examples from the literature and the Protein Data Bank

  14. Statistical perspectives on inverse problems

    DEFF Research Database (Denmark)

    Andersen, Kim Emil

    of the interior of an object from electrical boundary measurements. One part of this thesis concerns statistical approaches for solving, possibly non-linear, inverse problems. Thus inverse problems are recasted in a form suitable for statistical inference. In particular, a Bayesian approach for regularisation...... problem is given in terms of probability distributions. Posterior inference is obtained by Markov chain Monte Carlo methods and new, powerful simulation techniques based on e.g. coupled Markov chains and simulated tempering is developed to improve the computational efficiency of the overall simulation......Inverse problems arise in many scientific disciplines and pertain to situations where inference is to be made about a particular phenomenon from indirect measurements. A typical example, arising in diffusion tomography, is the inverse boundary value problem for non-invasive reconstruction...

  15. Applying Graph Theory to Problems in Air Traffic Management

    Science.gov (United States)

    Farrahi, Amir H.; Goldberg, Alan T.; Bagasol, Leonard N.; Jung, Jaewoo

    2017-01-01

    Graph theory is used to investigate three different problems arising in air traffic management. First, using a polynomial reduction from a graph partitioning problem, it isshown that both the airspace sectorization problem and its incremental counterpart, the sector combination problem are NP-hard, in general, under several simple workload models. Second, using a polynomial time reduction from maximum independent set in graphs, it is shown that for any fixed e, the problem of finding a solution to the minimum delay scheduling problem in traffic flow management that is guaranteed to be within n1-e of the optimal, where n is the number of aircraft in the problem instance, is NP-hard. Finally, a problem arising in precision arrival scheduling is formulated and solved using graph reachability. These results demonstrate that graph theory provides a powerful framework for modeling, reasoning about, and devising algorithmic solutions to diverse problems arising in air traffic management.

  16. Bernoulli Variational Problem and Beyond

    KAUST Repository

    Lorz, Alexander

    2013-12-17

    The question of \\'cutting the tail\\' of the solution of an elliptic equation arises naturally in several contexts and leads to a singular perturbation problem under the form of a strong cut-off. We consider both the PDE with a drift and the symmetric case where a variational problem can be stated. It is known that, in both cases, the same critical scale arises for the size of the singular perturbation. More interesting is that in both cases another critical parameter (of order one) arises that decides when the limiting behaviour is non-degenerate. We study both theoretically and numerically the values of this critical parameter and, in the symmetric case, ask if the variational solution leads to the same value as for the maximal solution of the PDE. Finally we propose a weak formulation of the limiting Bernoulli problem which incorporates both Dirichlet and Neumann boundary condition. © 2013 Springer-Verlag Berlin Heidelberg.

  17. An analysis of the perceived difficulties arising during the process of integrating management systems

    Directory of Open Access Journals (Sweden)

    Jesus Abad

    2016-09-01

    Originality/value: Most research emphasises the benefits of integrated management systems. By analysing the difficulties that arise during the integration process, this study contributes to fill a gap in the literature on the problems associated with processes of organisational change, in our case the integration of management systems.

  18. A comparative study of iterative solutions to linear systems arising in quantum mechanics

    International Nuclear Information System (INIS)

    Jing Yanfei; Huang Tingzhu; Duan Yong; Carpentieri, Bruno

    2010-01-01

    This study is mainly focused on iterative solutions with simple diagonal preconditioning to two complex-valued nonsymmetric systems of linear equations arising from a computational chemistry model problem proposed by Sherry Li of NERSC. Numerical experiments show the feasibility of iterative methods to some extent when applied to the problems and reveal the competitiveness of our recently proposed Lanczos biconjugate A-orthonormalization methods to other classic and popular iterative methods. By the way, experiment results also indicate that application specific preconditioners may be mandatory and required for accelerating convergence.

  19. Current problems arising from the new law relating to franchise duties; Aktuelle Probleme des neuen Konzessionsabgabenrechts

    Energy Technology Data Exchange (ETDEWEB)

    Becker, P.

    1996-12-31

    The contribution examines the advantages and drawbacks of the new ordinance in German law relating to payment of franchise duties. The ordinance may bring about new problems if abused as a means of bringing pressure to bear in negotiations for takeover of existing electric or gas supply systems by local governments. The author analyses the legitimation of such exploitation of the franchise duty and in this context the general legal framework. (orig./CB) [Deutsch] Der Beitrag untersucht Vor- und Nachteile der neuen Verordnung im Konzessionsabgabenrecht, die im Hinblick auf Auseinandersetzungen um die ``Ubernahme von Strom- oder Gasversorgungssystemen durch Gemeinden neue Probleme mit sich bringen koennte, wenn Konzessionsabgaben als Druckmittel eingesetzt werden. Der Autor analysiert die Zulaessigkeit eines derartigen Einsatzes und in diesem Zusammenhang auch die rechtliche Basis der Konzessionsabgaben. (orig./CB)

  20. B-spline solution of a singularly perturbed boundary value problem arising in biology

    International Nuclear Information System (INIS)

    Lin Bin; Li Kaitai; Cheng Zhengxing

    2009-01-01

    We use B-spline functions to develop a numerical method for solving a singularly perturbed boundary value problem associated with biology science. We use B-spline collocation method, which leads to a tridiagonal linear system. The accuracy of the proposed method is demonstrated by test problems. The numerical result is found in good agreement with exact solution.

  1. A numerical solution of a singular boundary value problem arising in boundary layer theory.

    Science.gov (United States)

    Hu, Jiancheng

    2016-01-01

    In this paper, a second-order nonlinear singular boundary value problem is presented, which is equivalent to the well-known Falkner-Skan equation. And the one-dimensional third-order boundary value problem on interval [Formula: see text] is equivalently transformed into a second-order boundary value problem on finite interval [Formula: see text]. The finite difference method is utilized to solve the singular boundary value problem, in which the amount of computational effort is significantly less than the other numerical methods. The numerical solutions obtained by the finite difference method are in agreement with those obtained by previous authors.

  2. On the Linearized Darboux Equation Arising in Isometric Embedding of the Alexandrov Positive Annulus

    Institute of Scientific and Technical Information of China (English)

    Chunhe LI

    2013-01-01

    In the present paper,the solvability condition of the linearized Gauss-Codazzi system and the solutions to the homogenous system are given.In the meantime,the Solvability of a relevant linearized Darboux equation is given.The equations are arising in a geometric problem which is concerned with the realization of the Alexandrov's positive annulus in R3.

  3. Problems of Software Detection of Periodic Features in a Time ...

    African Journals Online (AJOL)

    Problems arise when attempts are made to extract automatically, visually obvious periodic features indicative of defects in a vibration time series for diagnosis using computers. Such problems may be interpretational in nature arising either from insufficient knowledge of the mechanism, or the convolution of the source signal ...

  4. Problem specific heuristics for group scheduling problems in cellular manufacturing

    OpenAIRE

    Neufeld, Janis Sebastian

    2016-01-01

    The group scheduling problem commonly arises in cellular manufacturing systems, where parts are grouped into part families. It is characterized by a sequencing task on two levels: on the one hand, a sequence of jobs within each part family has to be identified while, on the other hand, a family sequence has to be determined. In order to solve this NP-hard problem usually heuristic solution approaches are used. In this thesis different aspects of group scheduling are discussed and problem spec...

  5. Primary extradural meningioma arising from the calvarium

    Directory of Open Access Journals (Sweden)

    N Ravi

    2013-06-01

    Full Text Available Meningiomas are the most common intracranial tumours. Meningiomas arising at other locations are termed primary extradural meningiomas (EDM and are rare. Here we report a case of EDM arising from the calvarium – a primary calvarial meningioma (PCM.

  6. Squamous cell carcinoma arising in an odontogenic cyst

    International Nuclear Information System (INIS)

    Yu, Jae Jung; Hwang, Eui Hwan; Lee, Sang Rae; Choi, Jeong Hee

    2003-01-01

    Squamous cell carcinoma arising in an odontogenic cyst is uncommon. The diagnosis of carcinoma arising in a cyst requires that there must be an area of microscopic transition from the benign epithelial cyst lining to the invasive squamous cell carcinoma. We report a histopathologically proven case of squamous cell carcinoma arising in a residual mandibular cyst in a 54-year-old woman.

  7. A Spectral Multi-Domain Penalty Method for Elliptic Problems Arising From a Time-Splitting Algorithm For the Incompressible Navier-Stokes Equations

    Science.gov (United States)

    Diamantopoulos, Theodore; Rowe, Kristopher; Diamessis, Peter

    2017-11-01

    The Collocation Penalty Method (CPM) solves a PDE on the interior of a domain, while weakly enforcing boundary conditions at domain edges via penalty terms, and naturally lends itself to high-order and multi-domain discretization. Such spectral multi-domain penalty methods (SMPM) have been used to solve the Navier-Stokes equations. Bounds for penalty coefficients are typically derived using the energy method to guarantee stability for time-dependent problems. The choice of collocation points and penalty parameter can greatly affect the conditioning and accuracy of a solution. Effort has been made in recent years to relate various high-order methods on multiple elements or domains under the umbrella of the Correction Procedure via Reconstruction (CPR). Most applications of CPR have focused on solving the compressible Navier-Stokes equations using explicit time-stepping procedures. A particularly important aspect which is still missing in the context of the SMPM is a study of the Helmholtz equation arising in many popular time-splitting schemes for the incompressible Navier-Stokes equations. Stability and convergence results for the SMPM for the Helmholtz equation will be presented. Emphasis will be placed on the efficiency and accuracy of high-order methods.

  8. Solitary Fibrous Tumor Arising from Stomach: CT Findings

    Science.gov (United States)

    Park, Sung Hee; Kwon, Jieun; Park, Jong-pil; Park, Mi-Suk; Lim, Joon Seok; Kim, Joo Hee; Kim, Ki Whang

    2007-01-01

    Solitary fibrous tumors are spindle-cell neoplasms that usually develop in the pleura and peritoneum, and rarely arise in the stomach. To our knowledge, there is only one case reporting a solitary fibrous tumor arising from stomach in the English literature. Here we report the case of a 26-year-old man with a large solitary fibrous tumor arising from the stomach which involved the submucosa and muscular layer and resembled a gastrointestinal stromal tumor in the stomach, based on what was seen during abdominal computed tomography. A solitary fibrous tumor arising from the stomach, although rare, could be considered as a diagnostic possibility for gastric submucosal tumors. PMID:18159603

  9. Numerical study of nonlinear singular fractional differential equations arising in biology by operational matrix of shifted Legendre polynomials

    Directory of Open Access Journals (Sweden)

    D. Jabari Sabeg

    2016-10-01

    Full Text Available In this paper, we present a new computational method for solving nonlinear singular boundary value problems of fractional order arising in biology. To this end, we apply the operational matrices of derivatives of shifted Legendre polynomials to reduce such problems to a system of nonlinear algebraic equations. To demonstrate the validity and applicability of the presented method, we present some numerical examples.

  10. Quantum Statistics and Entanglement Problems

    OpenAIRE

    Trainor, L. E. H.; Lumsden, Charles J.

    2002-01-01

    Interpretations of quantum measurement theory have been plagued by two questions, one concerning the role of observer consciousness and the other the entanglement phenomenon arising from the superposition of quantum states. We emphasize here the remarkable role of quantum statistics in describing the entanglement problem correctly and discuss the relationship to issues arising from current discussions of intelligent observers in entangled, decohering quantum worlds.

  11. Reinforcement learning solution for HJB equation arising in constrained optimal control problem.

    Science.gov (United States)

    Luo, Biao; Wu, Huai-Ning; Huang, Tingwen; Liu, Derong

    2015-11-01

    The constrained optimal control problem depends on the solution of the complicated Hamilton-Jacobi-Bellman equation (HJBE). In this paper, a data-based off-policy reinforcement learning (RL) method is proposed, which learns the solution of the HJBE and the optimal control policy from real system data. One important feature of the off-policy RL is that its policy evaluation can be realized with data generated by other behavior policies, not necessarily the target policy, which solves the insufficient exploration problem. The convergence of the off-policy RL is proved by demonstrating its equivalence to the successive approximation approach. Its implementation procedure is based on the actor-critic neural networks structure, where the function approximation is conducted with linearly independent basis functions. Subsequently, the convergence of the implementation procedure with function approximation is also proved. Finally, its effectiveness is verified through computer simulations. Copyright © 2015 Elsevier Ltd. All rights reserved.

  12. Wilms tumor arising in extracoelomic paravertebral soft tissues.

    LENUS (Irish Health Repository)

    Mulligan, Linda

    2012-02-01

    Extrarenal Wilms tumor (ERWT) is a well-established entity which most commonly arises within the genitourinary tract, including intracoelomic paranephric soft tissue. Rarely, ERWT arises within teratoma, and it tends to occur predominantly in distinct settings, such as females with spinal defects and males with testicular teratomas. We report a unique ERWT arising within an extracoelomic teratoma of the paraspinal musculature, thereby expanding the range of reported locations for this unusual tumor.

  13. Esophageal leiomyoma arising in an epiphrenic diverticulum

    International Nuclear Information System (INIS)

    Hamilton, S.

    1988-01-01

    A 32-year old woman was found at surgery to have an esophageal leiomyoma arising within an epiphrenic diverticulum. These uncommon conditions may rarely occur together, causing difficulty in diagnosis of the leiomyoma. Other neoplasms may also arise in an epiphrenic diverticulum and should be borne in mind in this situation. (orig.)

  14. U(1) problem

    Energy Technology Data Exchange (ETDEWEB)

    McDougall, N.A. (Oxford Univ. (UK). Dept. of Theoretical Physics)

    1984-08-23

    The resolution of the U(1) problem requires the quark condensates to have a specific THETA dependence. We show that the required THETA dependence arises naturally upon application of the index theorem during the calculation of the dynamically generated quark mass.

  15. Some Problems for Biolinguistics

    Directory of Open Access Journals (Sweden)

    Derek Bickerton

    2014-03-01

    Full Text Available Biolinguistics will have to face and resolve several problems before it can achieve a pivotal position in the human sciences. Its relationship to the Minimalist Program is ambiguous, creating doubts as to whether it is a genuine subdiscipline or merely another name for a particular linguistic theory. Equally ambiguous is the relationship it assumes between ‘knowledge of language’ and the neural mechanisms that actually construct sentences. The latter issue raises serious questions about the validity of covert syntactic operations. Further problems arise from the attitudes of many biolinguists towards natural selection and evo-devo: The first they misunderstand, the second they both misunderstand and overestimate. One consequence is a one-sided approach to language evolution crucially involving linguistic ‘precursors’ and the protolanguage hypothesis. Most of these problems arise through the identification of biolinguistics with internalist and essentialist approaches to language, thereby simultaneously narrowing its scope and hindering its acceptance by biologists.

  16. An inverse problem for a semilinear parabolic equation arising from cardiac electrophysiology

    Science.gov (United States)

    Beretta, Elena; Cavaterra, Cecilia; Cerutti, M. Cristina; Manzoni, Andrea; Ratti, Luca

    2017-10-01

    In this paper we develop theoretical analysis and numerical reconstruction techniques for the solution of an inverse boundary value problem dealing with the nonlinear, time-dependent monodomain equation, which models the evolution of the electric potential in the myocardial tissue. The goal is the detection of an inhomogeneity \

  17. Climate is the real challenge, not shortage. New problems arising for global energy supply

    Energy Technology Data Exchange (ETDEWEB)

    Pestel, E.

    1988-11-01

    The author of the article is Professor E. Pestel who, as an executive member of the Club of Rome, belongs to the group of experts who first gave impetus to start thinking about the global problems of mankind. In his publications on the problems linked with CO/sub 2/ emission he explains the unavoidable dilemma created by the growing world population and the growing demand for energy on the one hand, and the resulting hazards to the global climate on the other. His analyses take away the soft cushion of hopeful make-believe still widespread in the Western World, and in his capacity as an expert and realist he decidedly calls for decisions and measures to tackle the problem.

  18. Solitary Fibrous Tumor Arising from Stomach: CT Findings

    OpenAIRE

    Park, Sung Hee; Kim, Myeong-Jin; Kwon, Jieun; Park, Jong-pil; Park, Mi-Suk; Lim, Joon Seok; Kim, Joo Hee; Kim, Ki Whang

    2007-01-01

    Solitary fibrous tumors are spindle-cell neoplasms that usually develop in the pleura and peritoneum, and rarely arise in the stomach. To our knowledge, there is only one case reporting a solitary fibrous tumor arising from stomach in the English literature. Here we report the case of a 26-year-old man with a large solitary fibrous tumor arising from the stomach which involved the submucosa and muscular layer and resembled a gastrointestinal stromal tumor in the stomach, based on what was see...

  19. Proxy-produced ethnographic work: what are the problems, issues, and dilemmas arising from proxy ethnography?

    DEFF Research Database (Denmark)

    Martinussen, Marie Louise; Højbjerg, Karin; Tamborg, Andreas Lindenskov

    2018-01-01

    This article addresses the implications of research-student cooperation in the production of empirical material. For the student to replace the experienced researcher and work under the researcher’s supervision, we call such work proxy-produced ethnographic work. The specific relations...... and positions arising from such a setup between the teacher/researcher and the proxy ethnographer/student are found to have implications for the ethnographies produced. This article’s main focus is to show how these relations and positions have not distorted the ethnographic work and the ethnographies but......, rather, have oriented it in certain ways. It is shown how the participating researchers – both senior and junior - have distinctive, incorporated dispositions with which they pre-consciously participate in an implicit and subtle relation that can make it very easy to overlook distortions during...

  20. Primary extradural meningioma arising from the calvarium | Ravi ...

    African Journals Online (AJOL)

    Meningiomas are the most common intracranial tumours. Meningiomas arising at other locations are termed primary extradural meningiomas (EDMs) and are rare. Here we report a case of EDM arising from the calvarium – a primary calvarial meningioma (PCM).

  1. Representation of discrete Steklov-Poincare operator arising in domain decomposition methods in wavelet basis

    Energy Technology Data Exchange (ETDEWEB)

    Jemcov, A.; Matovic, M.D. [Queen`s Univ., Kingston, Ontario (Canada)

    1996-12-31

    This paper examines the sparse representation and preconditioning of a discrete Steklov-Poincare operator which arises in domain decomposition methods. A non-overlapping domain decomposition method is applied to a second order self-adjoint elliptic operator (Poisson equation), with homogeneous boundary conditions, as a model problem. It is shown that the discrete Steklov-Poincare operator allows sparse representation with a bounded condition number in wavelet basis if the transformation is followed by thresholding and resealing. These two steps combined enable the effective use of Krylov subspace methods as an iterative solution procedure for the system of linear equations. Finding the solution of an interface problem in domain decomposition methods, known as a Schur complement problem, has been shown to be equivalent to the discrete form of Steklov-Poincare operator. A common way to obtain Schur complement matrix is by ordering the matrix of discrete differential operator in subdomain node groups then block eliminating interface nodes. The result is a dense matrix which corresponds to the interface problem. This is equivalent to reducing the original problem to several smaller differential problems and one boundary integral equation problem for the subdomain interface.

  2. Introduction to inverse problems for differential equations

    CERN Document Server

    Hasanov Hasanoğlu, Alemdar

    2017-01-01

    This book presents a systematic exposition of the main ideas and methods in treating inverse problems for PDEs arising in basic mathematical models, though it makes no claim to being exhaustive. Mathematical models of most physical phenomena are governed by initial and boundary value problems for PDEs, and inverse problems governed by these equations arise naturally in nearly all branches of science and engineering. The book’s content, especially in the Introduction and Part I, is self-contained and is intended to also be accessible for beginning graduate students, whose mathematical background includes only basic courses in advanced calculus, PDEs and functional analysis. Further, the book can be used as the backbone for a lecture course on inverse and ill-posed problems for partial differential equations. In turn, the second part of the book consists of six nearly-independent chapters. The choice of these chapters was motivated by the fact that the inverse coefficient and source problems considered here a...

  3. Problem-Solving during Shared Reading at Kindergarten

    Science.gov (United States)

    Gosen, Myrte N.; Berenst, Jan; de Glopper, Kees

    2015-01-01

    This paper reports on a conversation analytic study of problem-solving interactions during shared reading at three kindergartens in the Netherlands. It illustrates how teachers and pupils discuss book characters' problems that arise in the events in the picture books. A close analysis of the data demonstrates that problem-solving interactions do…

  4. Relationships between Problem Behaviors and Academic Achievement in Adolescents: The Unique Role of Attention Problems.

    Science.gov (United States)

    Barriga, Alvaro Q.; Doran, Jeffrey W.; Newell, Stephanie B.; Morrison, Elizabeth M.; Barbetti, Victor; Robbins, Brent Dean

    2002-01-01

    This study examined relationships among eight teacher-reported problem behavior syndromes and standardized measures of academic achievement among 58 adolescents in an alternative school. Analysis suggested association between attention problems and academic achievement was primarily due to inattention component of the syndrome rather than the…

  5. An abstract approach to some spectral problems of direct sum differential operators

    Directory of Open Access Journals (Sweden)

    Maksim S. Sokolov

    2003-07-01

    Full Text Available In this paper, we study the common spectral properties of abstract self-adjoint direct sum operators, considered in a direct sum Hilbert space. Applications of such operators arise in the modelling of processes of multi-particle quantum mechanics, quantum field theory and, specifically, in multi-interval boundary problems of differential equations. We show that a direct sum operator does not depend in a straightforward manner on the separate operators involved. That is, on having a set of self-adjoint operators giving a direct sum operator, we show how the spectral representation for this operator depends on the spectral representations for the individual operators (the coordinate operators involved in forming this sum operator. In particular it is shown that this problem is not immediately solved by taking a direct sum of the spectral properties of the coordinate operators. Primarily, these results are to be applied to operators generated by a multi-interval quasi-differential system studied, in the earlier works of Ashurov, Everitt, Gesztezy, Kirsch, Markus and Zettl. The abstract approach in this paper indicates the need for further development of spectral theory for direct sum differential operators.

  6. Numerical Methods for Solution of the Extended Linear Quadratic Control Problem

    DEFF Research Database (Denmark)

    Jørgensen, John Bagterp; Frison, Gianluca; Gade-Nielsen, Nicolai Fog

    2012-01-01

    In this paper we present the extended linear quadratic control problem, its efficient solution, and a discussion of how it arises in the numerical solution of nonlinear model predictive control problems. The extended linear quadratic control problem is the optimal control problem corresponding...... to the Karush-Kuhn-Tucker system that constitute the majority of computational work in constrained nonlinear and linear model predictive control problems solved by efficient MPC-tailored interior-point and active-set algorithms. We state various methods of solving the extended linear quadratic control problem...... and discuss instances in which it arises. The methods discussed in the paper have been implemented in efficient C code for both CPUs and GPUs for a number of test examples....

  7. The Soccer-Ball Problem

    Science.gov (United States)

    Hossenfelder, Sabine

    2014-07-01

    The idea that Lorentz-symmetry in momentum space could be modified but still remain observer-independent has received quite some attention in the recent years. This modified Lorentz-symmetry, which has been argued to arise in Loop Quantum Gravity, is being used as a phenomenological model to test possibly observable effects of quantum gravity. The most pressing problem in these models is the treatment of multi-particle states, known as the 'soccer-ball problem'. This article briefly reviews the problem and the status of existing solution attempts.

  8. Dioxins: diagnostic and prognostic challenges arising from complex mechanisms

    DEFF Research Database (Denmark)

    Rysavy, Noel M.; Maaetoft-Udsen, Kristina; Turner, Helen

    2013-01-01

    Dioxins are ubiquitous environmental challenges to humans, with a pervasiveness that arises from 200?years of rapid industrialization and mechanization of Western societies and which is now extending into the developing world. In spite of their penetrance of the human biota, these compounds...... such as cancer and diabetes, which are already multifactorial and highly complex, creates the context for the current review paper. Here, we summarize dioxin exposure paradigms and the resulting physiological effects that have been documented in animals and humans. Novel insights into potential endogenous end...... exogenous ligands, as well as the mechanisms by which these ligands impact acute and chronic cellular processes, are discussed. We develop the idea that the diagnosis of dioxin exposure, the subtleties of the cellular effects of the compounds and prognosis of the long-term effects of exposure are problems...

  9. Customer-centered problem solving.

    Science.gov (United States)

    Samelson, Q B

    1999-11-01

    If there is no single best way to attract new customers and retain current customers, there is surely an easy way to lose them: fail to solve the problems that arise in nearly every buyer-supplier relationship, or solve them in an unsatisfactory manner. Yet, all too frequently, companies do just that. Either we deny that a problem exists, we exert all our efforts to pin the blame elsewhere, or we "Band-Aid" the problem instead of fixing it, almost guaranteeing that we will face it again and again.

  10. Problems in Recording the Electrocardiogram.

    Science.gov (United States)

    Webster, John G.

    The unwanted signals that arise in electrocardiography are discussed. A technical background of electrocardiography is given, along with teaching techniques that educate students of medical instrumentation to solve the problems caused by these signals. (MJH)

  11. Endogeneously arising network allocation rules

    NARCIS (Netherlands)

    Slikker, M.

    2006-01-01

    In this paper we study endogenously arising network allocation rules. We focus on three allocation rules: the Myerson value, the position value and the component-wise egalitarian solution. For any of these three rules we provide a characterization based on component efficiency and some balanced

  12. High intensity heat pulse problem

    International Nuclear Information System (INIS)

    Yalamanchili, R.

    1977-01-01

    The use of finite-difference methods for the solution of partial differential equations is common in both design and research and development because of the advance of computers. The numerical methods for the unsteady heat diffusion equation received most attention not only because of heat transfer problems but also happened to be the basis for any study of parabolic partial differential equations. It is common to test the heat equation first even the methods developed for complex nonlinear parabolic partial differential equations arising in fluid mechanics or convective heat transfer. It is concluded that the finite-element method is conservative in both stability and monoscillation characteristics than the finite-difference method but not as conservative as the method of weighted-residuals. Since the finite-element is unique because of Gurtin's variational principle and numerous finite-differences can be constructed, it is found that some finite-difference schemes are better than the finite-element scheme in accuracy also. Therefore, further attention is focused here on finite-difference schemes only. Various physical problems are considered in the field of heat transfer. These include: numerous problems in steady and unsteady heat conduction; heat pulse problems, such as, plasma torch; problems arising from machining operations, such as, abrasive cut-off and surface grinding. (Auth.)

  13. Carcinoma arising in thyroglossal remnants

    NARCIS (Netherlands)

    van Vuuren, P. A.; Balm, A. J.; Gregor, R. T.; Hilgers, F. J.; Loftus, B. M.; Delprat, C. C.; Rutgers, E. J.

    1994-01-01

    Three patients with a papillary carcinoma arising in a thyroglossal duct cyst are presented and the literature is reviewed. This rare malignancy is seen mostly in women between the ages of 20 and 50 years. The distribution of carcinoma subtypes differs from that of thyroid carcinomas and

  14. Semidefinite linear complementarity problems

    International Nuclear Information System (INIS)

    Eckhardt, U.

    1978-04-01

    Semidefinite linear complementarity problems arise by discretization of variational inequalities describing e.g. elastic contact problems, free boundary value problems etc. In the present paper linear complementarity problems are introduced and the theory as well as the numerical treatment of them are described. In the special case of semidefinite linear complementarity problems a numerical method is presented which combines the advantages of elimination and iteration methods without suffering from their drawbacks. This new method has very attractive properties since it has a high degree of invariance with respect to the representation of the set of all feasible solutions of a linear complementarity problem by linear inequalities. By means of some practical applications the properties of the new method are demonstrated. (orig.) [de

  15. Adenosarcoma arising in hepatic endometriosis

    International Nuclear Information System (INIS)

    N'Senda, P.; Dahan, H.; Tubiana, J.M.; Arrive, L.; Wendum, D.; Balladur, P.

    2000-01-01

    We report a case of adenosarcoma arising in hepatic endometriosis. Both CT and MR scans demontrated a huge heterogeneous mass containing septated, thick-walled cystic lesions. After enlarged right hepatectomy, the patient was asymptomatic with no abnormalities at liver and abdominal CT scan at 2-year follow-up. (orig.)

  16. Adenosarcoma arising in hepatic endometriosis

    Energy Technology Data Exchange (ETDEWEB)

    N' Senda, P.; Dahan, H.; Tubiana, J.M.; Arrive, L. [Service de Radiologie, Hopital Saint-Antoine, 75 - Paris (France); Wendum, D. [Service d' Anatomie Pathologie, Hopital Saint-Antoine, 75 - Paris (France); Balladur, P. [Service de Chirurgie Digestive et Generale, Hopital Saint-Antoine, 75 - Paris (France)

    2000-08-01

    We report a case of adenosarcoma arising in hepatic endometriosis. Both CT and MR scans demontrated a huge heterogeneous mass containing septated, thick-walled cystic lesions. After enlarged right hepatectomy, the patient was asymptomatic with no abnormalities at liver and abdominal CT scan at 2-year follow-up. (orig.)

  17. Source terms for airborne radioactivity arising from uranium mill wastes

    International Nuclear Information System (INIS)

    O'Riordan, M.C.; Downing, A.L.

    1978-01-01

    One of the problems in assessing the radiological impact of uranium milling is to determine the rates of release to the air of material from the various sources of radioactivity. Such source terms are required for modelling the transport of radioactive material in the atmosphere. Activity arises from various point and area sources in the mill itself and from the mill tailings. The state of the tailings changes in time from slurry to solid. A layer of water may be maintained over the solids during the life of the mine, and the tailings may be covered with inert material on abandonment. Releases may be both gaseous and particulate. This paper indicates ways in which radon emanation and the suspension of long-lived particulate activity might be quantified, and areas requiring further exploration are identified

  18. Visual integration dysfunction in schizophrenia arises by the first psychotic episode and worsens with illness duration

    OpenAIRE

    Keane, Brian P.; Paterno, Danielle; Kastner, Sabine; Silverstein, Steven M.

    2016-01-01

    Visual integration dysfunction characterizes schizophrenia, but prior studies have not yet established whether the problem arises by the first psychotic episode or worsens with illness duration. To investigate the issue, we compared chronic schizophrenia patients (SZs), first episode psychosis patients (FEs), and well-matched healthy controls on a brief but sensitive psychophysical task in which subjects attempted to locate an integrated shape embedded in noise. Task difficulty depended on th...

  19. CALCULUS FROM THE PAST: MULTIPLE DELAY SYSTEMS ARISING IN CANCER CELL MODELLING

    KAUST Repository

    WAKE, G. C.; BYRNE, H. M.

    2013-01-01

    Nonlocal calculus is often overlooked in the mathematics curriculum. In this paper we present an interesting new class of nonlocal problems that arise from modelling the growth and division of cells, especially cancer cells, as they progress through the cell cycle. The cellular biomass is assumed to be unstructured in size or position, and its evolution governed by a time-dependent system of ordinary differential equations with multiple time delays. The system is linear and taken to be autonomous. As a result, it is possible to reduce its solution to that of a nonlinear matrix eigenvalue problem. This method is illustrated by considering case studies, including a model of the cell cycle developed recently by Simms, Bean and Koeber. The paper concludes by explaining how asymptotic expressions for the distribution of cells across the compartments can be determined and used to assess the impact of different chemotherapeutic agents. Copyright © 2013 Australian Mathematical Society.

  20. [Psychosocial problems and needs among cancer patients].

    Science.gov (United States)

    Mehlsen, Mimi Yung; Jensen, Anders Bonde; Zachariae, Bobby

    2007-04-30

    Cancer can have a serious impact on patient well-being and quality of life. The international literature reports a higher prevalence of psychosocial problems among cancer patients; primarily problems associated with difficulties in the family, duties in the household, work and leisure, sexuality and finances. The prevalence of these problems among Danish cancer patients is still unknown. A questionnaire assessing psychosocial problems and needs was mailed out to all patients who had been at the Department of Oncology, Aarhus Hospital in week 35, 2004. A total of 71%, i.e. 515 patients (34% men and 66% women) in active treatment and control returned the questionnaire. High levels of emotional distress were reported by 39% of the patients. High levels of distress were primarily related to problems with worries about their spouses, household duties, financial problems and experiences of insufficient collaboration between health care and social services. Between 19% and 25% of the patients required further help to handle emotional problems, legal and financial problems and practical problems in the home. A considerable proportion of oncology patients experience significant levels of distress. This group of distressed patients also report unmet needs for psychosocial support.

  1. Iterative method for solving a problem with mixed boundary conditions for biharmonic equation arising in fracture mechanics

    Directory of Open Access Journals (Sweden)

    Dang Quang A

    2013-02-01

    Full Text Available In this paper we consider a mixed boundary value problem for biharmonic equation of the Airy stress function which models a crack problem of a solid elastic plate. An iterative method for reducing the problem to a sequence of mixed problems for Poisson equations is proposed and investigated. The convergence of the method is established theoretically and illustrated on many numerical experiments.

  2. Cutaneous osteosarcoma arising from a burn scar

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Min A.; Yi, Jaehyuck [Kyungpook National University, Department of Radiology, College of Medicine, Daegu (Korea, Republic of); Kyungpook National University Hospital, Department of Radiology, Daegu (Korea, Republic of); Chae, Jong Min [Kyungpook National University, Department of Pathology, College of Medicine, Daegu (Korea, Republic of)

    2017-04-15

    Tumors that develop in old burn scars are usually squamous cell carcinomas. Sarcomas have also been reported, albeit rarely. To our knowledge, there has been only one case report of an extraskeletal osteosarcoma arising in a prior burn scar reported in the English-language literature, mainly discussing the clinicopathological features. Herein, we present a case of cutaneous osteosarcoma visualized as a mineralized soft-tissue mass arising from the scar associated with a previous skin burn over the back. This seems to be the first report describing the imaging features of a cutaneous osteosarcoma from an old burn scar. (orig.)

  3. On the U(1) problem

    International Nuclear Information System (INIS)

    McDougall, N.A.

    1984-01-01

    The resolution of the U(1) problem requires the quark condensates to have a specific THETA dependence. We show that the required THETA dependence arises naturally upon application of the index theorem during the calculation of the dynamically generated quark mass. (orig.)

  4. Fast multipole preconditioners for sparse matrices arising from elliptic equations

    KAUST Repository

    Ibeid, Huda

    2017-11-09

    Among optimal hierarchical algorithms for the computational solution of elliptic problems, the fast multipole method (FMM) stands out for its adaptability to emerging architectures, having high arithmetic intensity, tunable accuracy, and relaxable global synchronization requirements. We demonstrate that, beyond its traditional use as a solver in problems for which explicit free-space kernel representations are available, the FMM has applicability as a preconditioner in finite domain elliptic boundary value problems, by equipping it with boundary integral capability for satisfying conditions at finite boundaries and by wrapping it in a Krylov method for extensibility to more general operators. Here, we do not discuss the well developed applications of FMM to implement matrix-vector multiplications within Krylov solvers of boundary element methods. Instead, we propose using FMM for the volume-to-volume contribution of inhomogeneous Poisson-like problems, where the boundary integral is a small part of the overall computation. Our method may be used to precondition sparse matrices arising from finite difference/element discretizations, and can handle a broader range of scientific applications. It is capable of algebraic convergence rates down to the truncation error of the discretized PDE comparable to those of multigrid methods, and it offers potentially superior multicore and distributed memory scalability properties on commodity architecture supercomputers. Compared with other methods exploiting the low-rank character of off-diagonal blocks of the dense resolvent operator, FMM-preconditioned Krylov iteration may reduce the amount of communication because it is matrix-free and exploits the tree structure of FMM. We describe our tests in reproducible detail with freely available codes and outline directions for further extensibility.

  5. Fast multipole preconditioners for sparse matrices arising from elliptic equations

    KAUST Repository

    Ibeid, Huda; Yokota, Rio; Pestana, Jennifer; Keyes, David E.

    2017-01-01

    Among optimal hierarchical algorithms for the computational solution of elliptic problems, the fast multipole method (FMM) stands out for its adaptability to emerging architectures, having high arithmetic intensity, tunable accuracy, and relaxable global synchronization requirements. We demonstrate that, beyond its traditional use as a solver in problems for which explicit free-space kernel representations are available, the FMM has applicability as a preconditioner in finite domain elliptic boundary value problems, by equipping it with boundary integral capability for satisfying conditions at finite boundaries and by wrapping it in a Krylov method for extensibility to more general operators. Here, we do not discuss the well developed applications of FMM to implement matrix-vector multiplications within Krylov solvers of boundary element methods. Instead, we propose using FMM for the volume-to-volume contribution of inhomogeneous Poisson-like problems, where the boundary integral is a small part of the overall computation. Our method may be used to precondition sparse matrices arising from finite difference/element discretizations, and can handle a broader range of scientific applications. It is capable of algebraic convergence rates down to the truncation error of the discretized PDE comparable to those of multigrid methods, and it offers potentially superior multicore and distributed memory scalability properties on commodity architecture supercomputers. Compared with other methods exploiting the low-rank character of off-diagonal blocks of the dense resolvent operator, FMM-preconditioned Krylov iteration may reduce the amount of communication because it is matrix-free and exploits the tree structure of FMM. We describe our tests in reproducible detail with freely available codes and outline directions for further extensibility.

  6. Problems and Prospects for Economic Development in South ...

    African Journals Online (AJOL)

    The Nigerian environment today is faced with many problems of degradation arising from the impacts of human activities and natural phenomena with less prospect for economic development. Some of the problems include gully erosion; coastal erosion; flooding; drought and desertification; oil spillage and pollution; urban ...

  7. A problem solving model for regulatory policy making

    NARCIS (Netherlands)

    Boer, A.; van Engers, T.; Sileno, G.; Wyner, A.; Benn, N.

    2011-01-01

    In this paper we discuss how the interests and field theory promoted by public administration as a stakeholder in policy argumentation, directly arise from its problem solving activities, using the framework for public administration problem solving we proposed in [1,2]. We propose that calls for

  8. 32 CFR 537.19 - Demands arising from maritime claims.

    Science.gov (United States)

    2010-07-01

    ... 32 National Defense 3 2010-07-01 2010-07-01 true Demands arising from maritime claims. 537.19 Section 537.19 National Defense Department of Defense (Continued) DEPARTMENT OF THE ARMY CLAIMS AND ACCOUNTS CLAIMS ON BEHALF OF THE UNITED STATES § 537.19 Demands arising from maritime claims. (a) It is...

  9. Bernoulli Variational Problem and Beyond

    KAUST Repository

    Lorz, Alexander; Markowich, Peter A.; Perthame, Benoî t

    2013-01-01

    The question of 'cutting the tail' of the solution of an elliptic equation arises naturally in several contexts and leads to a singular perturbation problem under the form of a strong cut-off. We consider both the PDE with a drift and the symmetric

  10. 29 CFR 780.607 - “Primarily employed” in agriculture.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 3 2010-07-01 2010-07-01 false âPrimarily employedâ in agriculture. 780.607 Section 780... AGRICULTURE, PROCESSING OF AGRICULTURAL COMMODITIES, AND RELATED SUBJECTS UNDER THE FAIR LABOR STANDARDS ACT Employment in Agriculture and Livestock Auction Operations Under the Section 13(b)(13) Exemption Requirements...

  11. Optimal management with hybrid dynamics : The shallow lake problem

    NARCIS (Netherlands)

    Reddy, P.V.; Schumacher, Hans; Engwerda, Jacob; Camlibel, M.K.; Julius, A.A.; Pasumarthy, R.

    2015-01-01

    In this article we analyze an optimal management problem that arises in ecological economics using hybrid systems modeling. First, we introduce a discounted autonomous infinite horizon hybrid optimal control problem and develop few tools to analyze the necessary conditions for optimality. Next,

  12. Application of spectral Lanczos decomposition method to large scale problems arising geophysics

    Energy Technology Data Exchange (ETDEWEB)

    Tamarchenko, T. [Western Atlas Logging Services, Houston, TX (United States)

    1996-12-31

    This paper presents an application of Spectral Lanczos Decomposition Method (SLDM) to numerical modeling of electromagnetic diffusion and elastic waves propagation in inhomogeneous media. SLDM approximates an action of a matrix function as a linear combination of basis vectors in Krylov subspace. I applied the method to model electromagnetic fields in three-dimensions and elastic waves in two dimensions. The finite-difference approximation of the spatial part of differential operator reduces the initial boundary-value problem to a system of ordinary differential equations with respect to time. The solution to this system requires calculating exponential and sine/cosine functions of the stiffness matrices. Large scale numerical examples are in a good agreement with the theoretical error bounds and stability estimates given by Druskin, Knizhnerman, 1987.

  13. Four Different Tumors Arising in a Nevus Sebaceous

    Directory of Open Access Journals (Sweden)

    Takeshi Namiki

    2016-04-01

    Full Text Available Nevus sebaceous is known by its association with one or more secondary tumors, but more than three multiple tumors arising from a nevus sebaceous is extremely rare. A 67-year-old female presented with a light brown plaque on the back of her head that contained a dome-shaped black node and an erosive lesion. Histopathological examination showed atypical basaloid cells in the black node. At the periphery of that node, structures resembling follicular germs extruded from interlacing cords in the upper portion and tumor nests with sebocytes were in the lower portion. In the erosive lesion, papillated structures with an apocrine epithelium were observed. In the light brown plaque, enlargement of sebaceous lobules was noted. From those histopathological features, a diagnosis of syringocystadenoma papilliferum, sebaceoma, trichoblastoma and basal cell carcinoma arising from a nevus sebaceous was made. We discuss the rarity of multiple tumors arising from a nevus sebaceous.

  14. Esperanto and International Language Problems: A Research Bibliography.

    Science.gov (United States)

    Tonkin, Humphrey R.

    This bibliography is intended both for the researcher and for the occasional student of international language problems, particularly as these relate to the international language Esperanto. The book is divided into two main sections: Part One deals with problems arising from communication across national boundaries and the search for a solution…

  15. Modeling the problem of many hands in organisations

    NARCIS (Netherlands)

    Lima, de T.; Royakkers, L.M.M.; Dignum, F.P.M.; Coelho, H.; Studer, R.; Woodridge, M.J.

    2010-01-01

    In this paper we provide a formalism to reason about the problem of many hands in organisations. This is a problem that arises whenever the organisation is responsible for some undesirable outcome but none of its members can be held responsible for the outcome. The formalism proposed here is a logic

  16. [Chemical hazards arising from shale gas extraction].

    Science.gov (United States)

    Pakulska, Daria

    2015-01-01

    The development of the shale industry is gaining momentum and hence the analysis of chemical hazards to the environment and health of the local population is extreiely timely and important. Chemical hazards are created during the exploitation of all minerals, but in the case of shale gas production, there is much more uncertainty as regards to the effects of new technologies application. American experience suggests the increasing risk of environmental contamination, mainly groundwater. The greatest, concern is the incomplete knowledge of the composition of fluids used for fracturing shale rock and unpredictability of long-term effects of hydraulic fracturing for the environment and health of residents. High population density in the old continent causes the problem of chemical hazards which is much larger than in the USA. Despite the growing public discontent data on this subject are limited. First of all, there is no epidemiological studies to assess the relationship between risk factors, such as air and water pollution, and health effects in populations living in close proximity to gas wells. The aim of this article is to identify and discuss existing concepts on the sources of environmental contamination, an indication of the environment elements under pressure and potential health risks arising from shale gas extraction.

  17. Conjunctival lymphoma arising from reactive lymphoid hyperplasia

    Directory of Open Access Journals (Sweden)

    Fukuhara Junichi

    2012-09-01

    Full Text Available Abstract Extra nodal marginal zone B-cell lymphoma (EMZL of the conjunctiva typically arises in the marginal zone of mucosa-associated lymphoid tissue. The pathogenesis of conjunctival EMZL remains unknown. We describe an unusual case of EMZL arising from reactive lymphoid hyperplasia (RLH of the conjunctiva. A 35-year-old woman had fleshy salmon-pink conjunctival tumors in both eyes, oculus uterque (OU. Specimens from conjunctival tumors in the right eye, oculus dexter (OD, revealed a collection of small lymphoid cells in the stroma. Immunohistochemically, immunoglobulin (Ig light chain restriction was not detected. In contrast, diffuse atypical lymphoid cell infiltration was noted in the left eye, oculus sinister (OS, and positive for CD20, a marker for B cells OS. The tumors were histologically diagnosed as RLH OD, and EMZL OS. PCR analysis detected IgH gene rearrangement in the joining region (JH region OU. After 11 months, a re-biopsy specimen demonstrated EMZL based on compatible pathological and genetic findings OD, arising from RLH. This case suggests that even if the diagnosis of the conjunctival lymphoproliferative lesions is histologically benign, confirmation of the B-cell clonality by checking IgH gene rearrangement should be useful to predict the incidence of malignancy.

  18. 32 CFR 536.111 - Investigation of claims arising under international agreements (for those claims arising in the...

    Science.gov (United States)

    2010-07-01

    ... under international agreements (for those claims arising in the United States). Responsibility for... civilian component is attached, including the legal office of another armed force, to carry out the responsibility to investigate. The investigation will comply with the responsible Service's implementing claims...

  19. Do experiments suggest a hierarchy problem?

    International Nuclear Information System (INIS)

    Vissani, F.

    1997-09-01

    The hierarchy problem of the scalar sector of the standard model is reformulated, emphasizing the role of experimental facts that may suggest the existence of a new physics large mass scale, for instance indications of the instability of the matter, or indications in favor of massive neutrinos. In the see-saw model for the neutrino masses a hierarchy problem arises if the mass of the right-handed neutrinos is larger than approximatively 10 7 GeV: this problem, and its possible solutions, are discussed. (author)

  20. The co phylogeny reconstruction problem is NP-complete.

    Science.gov (United States)

    Ovadia, Y; Fielder, D; Conow, C; Libeskind-Hadas, R

    2011-01-01

    The co phylogeny reconstruction problem is that of finding minimum cost explanations of differences between historical associations. The problem arises in parasitology, molecular systematics, and biogeography. Existing software tools for this problem either have worst-case exponential time or use heuristics that do not guarantee optimal solutions. To date, no polynomial time optimal algorithms have been found for this problem. In this article, we prove that the problem is NP-complete, suggesting that future research on algorithms for this problem should seek better polynomial-time approximation algorithms and heuristics rather than optimal solutions.

  1. Squamous cell carcinoma arising in mature cystic teratoma of ovary

    Directory of Open Access Journals (Sweden)

    Ranu Patni

    2014-01-01

    Full Text Available Squamous cell carcinoma of the ovary is a rare condition and usually arises in mature cystic teratoma (MCT or dermoid cyst of the ovary. The reported incidence of malignant transformation in MCT is approximately 2%. A case of squamous cell carcinoma arising in a dermoid cyst of the ovary presenting at an early stage is presented here. A 53-year-old postmenopausal lady, presented with the complaint of pain in right lower abdomen since one month and a large complex abdomino-pelvic mass on examination and investigations. Final histopathology was reported as squamous cell carcinoma of left ovary arising from dermoid cyst and a benign dermoid cyst in the right ovary. The patient was assigned to squamous cell carcinoma of the ovary arising in a mature cystic teratoma, surgical stage Ic2. In view of the poor prognosis, adjuvant chemotherapy was started.

  2. Distributing Flexibility to Enhance Robustness in Task Scheduling Problems

    NARCIS (Netherlands)

    Wilmer, D.; Klos, T.B.; Wilson, M.

    2013-01-01

    Temporal scheduling problems occur naturally in many diverse application domains such as manufacturing, transportation, health and education. A scheduling problem arises if we have a set of temporal events (or variables) and some constraints on those events, and we have to find a schedule, which is

  3. The Cauchy problem for the Pavlov equation

    International Nuclear Information System (INIS)

    Grinevich, P G; Santini, P M; Wu, D

    2015-01-01

    Commutation of multidimensional vector fields leads to integrable nonlinear dispersionless PDEs that arise in various problems of mathematical physics and have been intensively studied in recent literature. This report aims to solve the scattering and inverse scattering problem for integrable dispersionless PDEs, recently introduced just at a formal level, concentrating on the prototypical example of the Pavlov equation, and to justify an existence theorem for global bounded solutions of the associated Cauchy problem with small data. (paper)

  4. Blow up of solutions to ordinary differential equations arising in nonlinear dispersive problems

    Directory of Open Access Journals (Sweden)

    Milena Dimova

    2018-03-01

    Full Text Available We study a new class of ordinary differential equations with blow up solutions. Necessary and sufficient conditions for finite blow up time are proved. Based on the new differential equation, a revised version of the concavity method of Levine is proposed. As an application we investigate the non-existence of global solutions to the Cauchy problem of Klein-Gordon, and to the double dispersive equations. We obtain necessary and sufficient condition for finite time blow up with arbitrary positive energy. A very general sufficient condition for blow up is also given.

  5. Boundary value problems on the half line in the theory of colloids

    Directory of Open Access Journals (Sweden)

    Ravi P. Agarwal

    2002-01-01

    Full Text Available We present existence results for some boundary value problems defined on infinite intervals. In particular our discussion includes a problem which arises in the theory of colloids.

  6. A taxonomy of inductive problems.

    Science.gov (United States)

    Kemp, Charles; Jern, Alan

    2014-02-01

    Inductive inferences about objects, features, categories, and relations have been studied for many years, but there are few attempts to chart the range of inductive problems that humans are able to solve. We present a taxonomy of inductive problems that helps to clarify the relationships between familiar inductive problems such as generalization, categorization, and identification, and that introduces new inductive problems for psychological investigation. Our taxonomy is founded on the idea that semantic knowledge is organized into systems of objects, features, categories, and relations, and we attempt to characterize all of the inductive problems that can arise when these systems are partially observed. Recent studies have begun to address some of the new problems in our taxonomy, and future work should aim to develop unified theories of inductive reasoning that explain how people solve all of the problems in the taxonomy.

  7. An Integrated Approach to the Ground Crew Rostering Problem with Work Patterns

    DEFF Research Database (Denmark)

    Lusby, Richard Martin; Hansen, Anders Dohn; Range, Troels Martin

    This paper addresses the Ground Crew Rostering Problem with Work Patterns, an important manpower planning problem arising in the ground operations of airline companies. We present a cutting stock based integer programming formulation of the problem and describe a powerful decomposition approach...

  8. Frequency response as a surrogate eigenvalue problem in topology optimization

    DEFF Research Database (Denmark)

    Andreassen, Erik; Ferrari, Federico; Sigmund, Ole

    2018-01-01

    This article discusses the use of frequency response surrogates for eigenvalue optimization problems in topology optimization that may be used to avoid solving the eigenvalue problem. The motivation is to avoid complications that arise from multiple eigenvalues and the computational complexity as...

  9. Malignant tumors arising in the maxillary region after radiation therapy

    International Nuclear Information System (INIS)

    Shimizu, Sawamichi; Shirahata, Yuichi; Uchida, Yutaka

    1984-01-01

    Although radiotherapy has proven of great therapeutic value in the treatment of malignant tumors, it should also be borne in mind that radiation has a serious potential risk of giving rise to a secondary malignancy. We recently experienced 2 cases each of carcinoma and sarcoma arising in the irradiated areas long after radiation therapy for malignant tumors. In these 4 cases, 2 males and 2 females, the primary neoplastic diseases were squamous cell carcinoma, epidermoid carcinoma, carcinoma of unknown pathology and malignant lymphoma, and the secondary tumors were epidermoid carcinoma, squamous cell carcinoma, osteosarcoma and chondrosarcoma, respectively. The sites of occurrence of these malignancies were invariably in the maxillary region; the mean latent period was 15 years, aside from an infantile case with a latent period of 5 years. In view of the primary diseases being malignant tumors the following criteria were set up for the diagnosis of radiation-induced malignancies: (1) the site of occurrence is within the confines of a previously irradiated area, (2) the latent period is prolonged and (3) the malignancy occurs as a double tumor. Therapy was primarily by operation. The prognosis was exceedingly ominous, the average survival time being 22 months. This was probably and mainly because of rapidity of tumor growth. Thus, the secondary tumors had already spread back to inward by the time they were first discovered. This should be kept in mind during a long-term follow-up of patients receiving radiotherapy for malignancy. (author)

  10. ARISE: American renaissance in science education

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-09-14

    The national standards and state derivatives must be reinforced by models of curricular reform. In this paper, ARISE presents one model based on a set of principles--coherence, integration of the sciences, movement from concrete ideas to abstract ones, inquiry, connection and application, sequencing that is responsive to how people learn.

  11. Rural development in Nigera: Problems and remedies | Eteng ...

    African Journals Online (AJOL)

    Rural development in Nigeria constitutes a fundamental problem. Over the years, rural development has been neglected. Rural areas are regarded as abodes of diseases, superstition, poverty, lethargy, low income and low productivity. This problem, which is primarily due to government non sustainable policy action ...

  12. Vanishing viscosity limits of mixed hyperbolic–elliptic systems arising in multilayer channel flows

    International Nuclear Information System (INIS)

    Papaefthymiou, E S; Papageorgiou, D T

    2015-01-01

    This study considers the spatially periodic initial value problem of 2 × 2 quasi-linear parabolic systems in one space dimension having quadratic polynomial flux functions. These systems arise physically in the interfacial dynamics of viscous immiscible multilayer channel flows. The equations describe the spatiotemporal evolution of phase-separating interfaces with dissipation arising from surface tension (fourth-order) and/or stable stratification effects (second-order). A crucial mathematical aspect of these systems is the presence of mixed hyperbolic–elliptic flux functions that provide the only source of instability. The study concentrates on scaled spatially 2π-periodic solutions as the dissipation vanishes, and in particular the behaviour of such limits when generalized dissipation operators (spanning second to fourth-order) are considered. Extensive numerical computations and asymptotic analysis suggest that the existence (or not) of bounded vanishing viscosity solutions depends crucially on the structure of the flux function. In the absence of linear terms (i.e. homogeneous flux functions) the vanishing viscosity limit does not exist in the L ∞ -norm. On the other hand, if linear terms in the flux function are present the computations strongly suggest that the solutions exist and are bounded in the L ∞ -norm as the dissipation vanishes. It is found that the key mechanism that provides such boundedness centres on persistent spatiotemporal hyperbolic–elliptic transitions. Strikingly, as the dissipation decreases, the flux function becomes almost everywhere hyperbolic except on a fractal set of elliptic regions, whose dimension depends on the order of the regularized operator. Furthermore, the spatial structures of the emerging weak solutions are found to support an increasing number of discontinuities (measure-valued solutions) located in the vicinity of the fractally distributed elliptic regions. For the unscaled problem, such spatially

  13. Issues arising in applying the BSS concepts

    International Nuclear Information System (INIS)

    Linsley, G.

    1997-01-01

    The following issues are discussed arising in applying the basic safety standard concepts: terminology, naturally occurring radionuclides, the exemption and clearance levels, management of very low level wastes, transboundary movements, the waste convention

  14. Dresses problems arising from hot-plant operation and their solution (1961)

    International Nuclear Information System (INIS)

    Rodier, J.; Bouzigues, H.; Boutot, P.

    1961-01-01

    This article deals with effective methods to struggle radioactive contamination using rationally designed working clothes. The choice of the cloth is important and cotton, because of its absorbent properties constitutes an effective barrier to radioelements failing on its surface. Clothing the personnel of large nuclear industrial concerns is a big problem which can only be solved by carefully studied methods. The decontamination and washing of large amounts of clothes whose flow increases during periods of radio-active incidents have to be treated as are those operations in hospital laundering. Linen washing by the German counter-current method (the Sulzman system) is of great value because of the volume which can be treated and, more important, because of the small amount of liquid waste produced. Dry cleaning is certainly a method of the future and is even more economic than the preceding one. In 'active' laundries, the control of clothing for residual contamination can constitute a serious bottleneck in the production of clean clothing if automatic high-speed machines are not used. The risk to the operating personnel comes solely from contamination of the atmosphere and of the surfaces. Because of this, the plant must be considered as an active zone in which are handled several tens of millicuries of dangerous emitters and several micro- curies of plutonium daily. (authors) [fr

  15. Algorithms and ordering heuristics for distributed constraint satisfaction problems

    CERN Document Server

    Wahbi , Mohamed

    2013-01-01

    DisCSP (Distributed Constraint Satisfaction Problem) is a general framework for solving distributed problems arising in Distributed Artificial Intelligence.A wide variety of problems in artificial intelligence are solved using the constraint satisfaction problem paradigm. However, there are several applications in multi-agent coordination that are of a distributed nature. In this type of application, the knowledge about the problem, that is, variables and constraints, may be logically or geographically distributed among physical distributed agents. This distribution is mainly due to p

  16. Electric reaction arising in bone subjected to mechanical loadings

    Science.gov (United States)

    Murasawa, Go; Cho, Hideo; Ogawa, Kazuma

    2006-03-01

    The aim of present study is the investigation of the electric reaction arising in bone subjected to mechanical loadings. Firstly, specimen was fabricated from femur of cow, and ultrasonic propagation in bone was measured by ultrasonic technique. Secondary, 4-point bending test was conducted up to fracture, and electric reaction arising in bone was measured during loading. Thirdly, cyclic 4-point bending test was conducted to investigate the effect of applied displacement speed on electric reaction.

  17. Chemical hazards arising from shale gas extraction

    Directory of Open Access Journals (Sweden)

    Daria Pakulska

    2015-02-01

    Full Text Available The development of the shale industry is gaining momentum and hence the analysis of chemical hazards to the environment and health of the local population is extremely timely and important. Chemical hazards are created during the exploitation of all minerals, but in the case of shale gas production, there is much more uncertainty as regards to the effects of new technologies application. American experience suggests the increasing risk of environmental contamination, mainly groundwater. The greatest concern is the incomplete knowledge of the composition of fluids used for fracturing shale rock and unpredictability of long-term effects of hydraulic fracturing for the environment and health of residents. High population density in the old continent causes the problem of chemical hazards which is much larger than in the USA. Despite the growing public discontent data on this subject are limited. First of all, there is no epidemiological studies to assess the relationship between risk factors, such as air and water pollution, and health effects in populations living in close proximity to gas wells. The aim of this article is to identify and discuss existing concepts on the sources of environmental contamination, an indication of the environment elements under pressure and potential health risks arising from shale gas extraction. Med Pr 2015;66(1:99–117

  18. Polyomino Problems to Confuse Computers

    Science.gov (United States)

    Coffin, Stewart

    2009-01-01

    Computers are very good at solving certain types combinatorial problems, such as fitting sets of polyomino pieces into square or rectangular trays of a given size. However, most puzzle-solving programs now in use assume orthogonal arrangements. When one departs from the usual square grid layout, complications arise. The author--using a computer,…

  19. Robust Consumption-Investment Problem on Infinite Horizon

    Energy Technology Data Exchange (ETDEWEB)

    Zawisza, Dariusz, E-mail: dariusz.zawisza@im.uj.edu.pl [Jagiellonian University in Krakow, Institute of Mathematics, Faculty of Mathematics and Computer Science (Poland)

    2015-12-15

    In our paper we consider an infinite horizon consumption-investment problem under a model misspecification in a general stochastic factor model. We formulate the problem as a stochastic game and finally characterize the saddle point and the value function of that game using an ODE of semilinear type, for which we provide a proof of an existence and uniqueness theorem for its solution. Such equation is interested on its own right, since it generalizes many other equations arising in various infinite horizon optimization problems.

  20. Riemann–Hilbert problem approach for two-dimensional flow inverse scattering

    Energy Technology Data Exchange (ETDEWEB)

    Agaltsov, A. D., E-mail: agalets@gmail.com [Faculty of Computational Mathematics and Cybernetics, Lomonosov Moscow State University, 119991 Moscow (Russian Federation); Novikov, R. G., E-mail: novikov@cmap.polytechnique.fr [CNRS (UMR 7641), Centre de Mathématiques Appliquées, Ecole Polytechnique, 91128 Palaiseau (France); IEPT RAS, 117997 Moscow (Russian Federation); Moscow Institute of Physics and Technology, Dolgoprudny (Russian Federation)

    2014-10-15

    We consider inverse scattering for the time-harmonic wave equation with first-order perturbation in two dimensions. This problem arises in particular in the acoustic tomography of moving fluid. We consider linearized and nonlinearized reconstruction algorithms for this problem of inverse scattering. Our nonlinearized reconstruction algorithm is based on the non-local Riemann–Hilbert problem approach. Comparisons with preceding results are given.

  1. Riemann–Hilbert problem approach for two-dimensional flow inverse scattering

    International Nuclear Information System (INIS)

    Agaltsov, A. D.; Novikov, R. G.

    2014-01-01

    We consider inverse scattering for the time-harmonic wave equation with first-order perturbation in two dimensions. This problem arises in particular in the acoustic tomography of moving fluid. We consider linearized and nonlinearized reconstruction algorithms for this problem of inverse scattering. Our nonlinearized reconstruction algorithm is based on the non-local Riemann–Hilbert problem approach. Comparisons with preceding results are given

  2. Attention problems and pathological gaming: resolving the 'chicken and egg' in a prospective analysis.

    Science.gov (United States)

    Ferguson, Christopher J; Ceranoglu, T Atilla

    2014-03-01

    Pathological gaming (PG) behaviors are behaviors which interfere with other life responsibilities. Continued debate exists regarding whether symptoms of PG behaviors are a unique phenomenon or arise from other mental health problems, including attention problems. Development of attention problems and occurrence of pathological gaming in 144 adolescents were followed during a 1-year prospective analysis. Teens and their parents reported on pathological gaming behaviors, attention problems, and current grade point average, as well as several social variables. Results were analyzed using regression and path analysis. Attention problems tended to precede pathological gaming behaviors, but the inverse was not true. Attention problems but not pathological gaming predicted lower GPA 1 year later. Current results suggest that pathological gaming arises from attention problems, but not the inverse. These results suggest that pathological gaming behaviors are symptomatic of underlying attention related mental health issues, rather than a unique phenomenon.

  3. Expansion of capacity of spent fuel pools and associated problems

    International Nuclear Information System (INIS)

    Francisco, J.L. De; Lopez-Cotarelo, J.; Ramos, J.M.

    1978-01-01

    Expanding the spent fuel storage pool capacity is a good solution for utilities facing the current shortage in fuel reprocessing capacity. The problems more likely to be found when expanding a spent fuel storage facility by using high density storage racks are reviewed. Basically three types of problems arise: 1) Problems related with the characteristics of the new facility. 2) Problems related with the works of expansion. 3) Problems related with the long term storage of large quantities of spent fuel. (author)

  4. Software problems in library automation in India

    OpenAIRE

    Francis, A. T.

    1998-01-01

    Important software problems faced by the library professionals in India are analysed and points out various compatibility and suitability issues in the selection of a library software. The paper also hints that these problems has affected the progress of computerisation of libraries. Upto date and detailed information on softwares available in India can prevent several issues that may arise in the course of computerisation. An agency/mechanism to continuously evaluate the softwares may be ...

  5. Anomalous Posterior Intercostal Arterial Trunk Arising From the Abdominal Aorta

    Energy Technology Data Exchange (ETDEWEB)

    Jie, Bing, E-mail: jbshh@163.com; Yu, Dong, E-mail: yudong-mail@126.com; Jiang, Sen, E-mail: jasfly77@vip.163.com [Tongji University School of Medicine, Department of Radiology, Shanghai Pulmonary Hospital (China)

    2016-04-15

    A common trunk of the ipsilateral posterior intercostal artery (PIA) arising from the thoracic aorta is usually an anatomical variation. However, a common trunk of bilateral posterior intercostal arterial trunk (PIAT) arising from the abdominal aorta is rare. It is important to recognize this anatomical variation of PIA when performing interventional radiological procedures. We present a rare case of an anomalous PIAT that originated from the abdominal aorta in a patient with hemoptysis caused by tuberculosis sequelae. Bilateral 4th to 11th PIAs arose from a common trunk and the trunk arising from the posterior aspect of the abdominal aorta at the level of T12/L1 intervertebral space. The pathological right 4th and 5th PIAs and bronchial arteries were embolized. Hemoptysis has been controlled for 3 months.

  6. A game theoretic approach to assignment problems

    NARCIS (Netherlands)

    Klijn, F.

    2000-01-01

    Game theory deals with the mathematical modeling and analysis of conflict and cooperation in the interaction of multiple decision makers. This thesis adopts two game theoretic methods to analyze a range of assignment problems that arise in various economic situations. The first method has as

  7. MAP estimators and their consistency in Bayesian nonparametric inverse problems

    KAUST Repository

    Dashti, M.

    2013-09-01

    We consider the inverse problem of estimating an unknown function u from noisy measurements y of a known, possibly nonlinear, map applied to u. We adopt a Bayesian approach to the problem and work in a setting where the prior measure is specified as a Gaussian random field μ0. We work under a natural set of conditions on the likelihood which implies the existence of a well-posed posterior measure, μy. Under these conditions, we show that the maximum a posteriori (MAP) estimator is well defined as the minimizer of an Onsager-Machlup functional defined on the Cameron-Martin space of the prior; thus, we link a problem in probability with a problem in the calculus of variations. We then consider the case where the observational noise vanishes and establish a form of Bayesian posterior consistency for the MAP estimator. We also prove a similar result for the case where the observation of can be repeated as many times as desired with independent identically distributed noise. The theory is illustrated with examples from an inverse problem for the Navier-Stokes equation, motivated by problems arising in weather forecasting, and from the theory of conditioned diffusions, motivated by problems arising in molecular dynamics. © 2013 IOP Publishing Ltd.

  8. MAP estimators and their consistency in Bayesian nonparametric inverse problems

    International Nuclear Information System (INIS)

    Dashti, M; Law, K J H; Stuart, A M; Voss, J

    2013-01-01

    We consider the inverse problem of estimating an unknown function u from noisy measurements y of a known, possibly nonlinear, map G applied to u. We adopt a Bayesian approach to the problem and work in a setting where the prior measure is specified as a Gaussian random field μ 0 . We work under a natural set of conditions on the likelihood which implies the existence of a well-posed posterior measure, μ y . Under these conditions, we show that the maximum a posteriori (MAP) estimator is well defined as the minimizer of an Onsager–Machlup functional defined on the Cameron–Martin space of the prior; thus, we link a problem in probability with a problem in the calculus of variations. We then consider the case where the observational noise vanishes and establish a form of Bayesian posterior consistency for the MAP estimator. We also prove a similar result for the case where the observation of G(u) can be repeated as many times as desired with independent identically distributed noise. The theory is illustrated with examples from an inverse problem for the Navier–Stokes equation, motivated by problems arising in weather forecasting, and from the theory of conditioned diffusions, motivated by problems arising in molecular dynamics. (paper)

  9. MYC Amplification in Angiosarcoma Arising from an Arteriovenous Graft Site

    Directory of Open Access Journals (Sweden)

    Kristen M. Paral

    2015-01-01

    Full Text Available Angiosarcoma arising in association with an arteriovenous graft (AVG or fistula is a unique clinicopathologic scenario that appears to be gaining recognition in the literature. Among reported cases, none has described high-level MYC gene amplification, a genetic aberration that is increasingly unifying the various clinicopathologic subdivisions of angiosarcoma. We therefore report the MYC gene status in a case of angiosarcoma arising at an AVG site.

  10. On the Combinatorics of SAT and the Complexity of Planar Problems

    DEFF Research Database (Denmark)

    Talebanfard, Navid

    In this thesis we study several problems arising in Boolean satisfiability ranging from lower bounds for SAT algorithms and proof systems to extremal properties of formulas. The first problem is about construction of hard instances for k-SAT algorithms. For PPSZ algorithm [40] we give the first...

  11. Optimal Stopping Problems Driven by Lévy Processes and Pasting Principles

    NARCIS (Netherlands)

    Surya, B.A.

    2007-01-01

    Solving optimal stopping problems driven by Lévy processes has been a challenging task and has found many applications in modern theory of mathematical finance. For example situations in which optimal stopping typically arise include the problem of finding the arbitrage-free price of the American

  12. Periodic solutions of an indefinite singular equation arising from the Kepler problem on the sphere

    Czech Academy of Sciences Publication Activity Database

    Hakl, Robert; Zamora, M.

    2018-01-01

    Roč. 70, č. 1 (2018), s. 173-190 ISSN 0008-414X Institutional support: RVO:67985840 Keywords : indefinite singularity * periodic solution * Kepler problem on S^1 Subject RIV: BA - General Mathematics OBOR OECD: Applied mathematics Impact factor: 0.963, year: 2016 https://cms.math.ca/10.4153/CJM-2016-050-1

  13. Sustainable Development and Spatial Planning: Some considerations arising from the Greek case

    Directory of Open Access Journals (Sweden)

    Pavlos Marinos Delladetsima

    2012-03-01

    Full Text Available The paper aims to elaborate on the notion of sustainable development in relation to spatial planning and to question its applicability based on the experience arising from the distinct socio-economic situation in Greece. Experience accumulated in the country with the adoption of sustainable development as a spatial policy concept proves to be in contradiction with perceptions that consider it as a basis for improving the plan making process and the planning system as whole. In this respect, it is argued that sustainable development is not a feasible proposition for planning in Greece and offers little to alleviate urban development and sprawl problems. Further, the paper highlights how a globalised approach to sustainable development and planning in Greece has made a negligible contribution to reinvigorating a weak and disjointed system, while also creating significant adverse effects in spatial policymaking.

  14. Defect Shape Recovering by Parameter Estimation Arising in Eddy Current Testing

    International Nuclear Information System (INIS)

    Kojima, Fumio

    2003-01-01

    This paper is concerned with a computational method for recovering a crack shape of steam generator tubes of nuclear plants. Problems on the shape identification are discussed arising in the characterization of a structural defect in a conductor using data of eddy current inspection. A surface defect on the generator tube ran be detected as a probe impedance trajectory by scanning a pancake type coil. First, a mathematical model of the inspection process is derived from the Maxwell's equation. Second, the input and output relation is given by the approximate model by virtue of the hybrid use of the finite element and boundary element method. In that model, the crack shape is characterized by the unknown coefficients of the B-spline function which approximates the crack shape geometry. Finally, a parameter estimation technique is proposed for recovering the crack shape using data from the probe coil. The computational experiments were successfully tested with the laboratory data

  15. Empiricism Verses Rationalism: Matters Arising in Medical Practice ...

    African Journals Online (AJOL)

    Empiricism Verses Rationalism: Matters Arising in Medical Practice. ... AFRREV STECH: An International Journal of Science and Technology ... entirely antagonistic to one another, one favoring the senses and the other favoring the mind.

  16. Substantive law problems in jurisdiction

    International Nuclear Information System (INIS)

    Sternberg, D.

    1977-01-01

    Substantive law problems in nuclear licensing procedure jurisdiction are discussed. Preconditions for the right to file a suit pursuant to section 42, sub-section 2 VwGO are investigated, in the context of which the necessity is pointed out to differentiate between normal operation and possible accidents. Furthermore, comments are made on the definition of 'facility' in terms of nuclear law, the understanding of which is rather decisive for the substantial scope of the nuclear licensing procedures. Also, legal problems are examined which arise from special forms of financing for nuclear power plant projects, in particular in connection with leasing financing. (HP) [de

  17. The Cauchy problem for the Pavlov equation with large data

    Science.gov (United States)

    Wu, Derchyi

    2017-08-01

    We prove a local solvability of the Cauchy problem for the Pavlov equation with large initial data by the inverse scattering method. The Pavlov equation arises in studies Einstein-Weyl geometries and dispersionless integrable models. Our theory yields a local solvability of Cauchy problems for a quasi-linear wave equation with a characteristic initial hypersurface.

  18. A theory of intelligence: networked problem solving in animal societies

    OpenAIRE

    Shour, Robert

    2009-01-01

    A society's single emergent, increasing intelligence arises partly from the thermodynamic advantages of networking the innate intelligence of different individuals, and partly from the accumulation of solved problems. Economic growth is proportional to the square of the network entropy of a society's population times the network entropy of the number of the society's solved problems.

  19. Requirements Elicitation Problems: A Literature Analysis

    Directory of Open Access Journals (Sweden)

    Bill Davey

    2015-06-01

    Full Text Available Requirements elicitation is the process through which analysts determine the software requirements of stakeholders. Requirements elicitation is seldom well done, and an inaccurate or incomplete understanding of user requirements has led to the downfall of many software projects. This paper proposes a classification of problem types that occur in requirements elicitation. The classification has been derived from a literature analysis. Papers reporting on techniques for improving requirements elicitation practice were examined for the problem the technique was designed to address. In each classification the most recent or prominent techniques for ameliorating the problems are presented. The classification allows the requirements engineer to be sensitive to problems as they arise and the educator to structure delivery of requirements elicitation training.

  20. Non-epiphyseal chondroblastoma arising in the iliac bone, and complicated by an aneurysmal bone cyst: a case report and review of the literature

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Jin; Kumar, Rajendra [The University of Texas MD Anderson Cancer Center, Department of Diagnostic Radiology, Houston, TX (United States); Raymond, A.K. [Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX (United States); Ayala, Alberto G. [The Methodist Hospital, Department of Pathology, Houston, TX (United States)

    2010-06-15

    Chondroblastoma is a benign bone tumor that typically arises in the epiphysis of a long bone. However, when it occurs in non-epiphyseal location in flat bones, it may create a diagnostic problem. We describe such a case of chondroblastoma arising in the iliac bone. A 29-year-old man was incidentally found to have a bony pelvic lesion while undergoing evaluation for Crohn's disease. The radiographs and CT revealed an expansile lytic lesion in the right iliac bone. A core biopsy of the lesion was performed. The histopathology revealed the lesion to be a chondroblastoma with secondary features of aneurysmal bone cyst. An en bloc surgical resection of the tumor was performed. (orig.)

  1. Cellular schwannoma arising from sigmoid mesocolon presenting ...

    African Journals Online (AJOL)

    Schwannomas are a type of peripheral nerve sheath tumors with clinically indolent behavior. Though, they can occur anywhere in body, the incidence in retroperitoneum, mediastinum, and pelvis is exceedingly rare. We present a case of a 58‑year‑old female with a massive twisted tumor arising from sigmoid mesocolon.

  2. Cellular Schwannoma Arising from Sigmoid Mesocolon Presenting ...

    African Journals Online (AJOL)

    Schwannomas are a type of peripheral nerve sheath tumors with clinically indolent behavior. Though, they can occur anywhere in body, the incidence in retroperitoneum, mediastinum, and pelvis is exceedingly rare. We present a case of a 58‑year‑old female with a massive twisted tumor arising from sigmoid mesocolon.

  3. A quadratic approximation-based algorithm for the solution of multiparametric mixed-integer nonlinear programming problems

    KAUST Repository

    Domí nguez, Luis F.; Pistikopoulos, Efstratios N.

    2012-01-01

    An algorithm for the solution of convex multiparametric mixed-integer nonlinear programming problems arising in process engineering problems under uncertainty is introduced. The proposed algorithm iterates between a multiparametric nonlinear

  4. Disgust sensitivity is primarily associated with purity-based moral judgments.

    Science.gov (United States)

    Wagemans, Fieke M A; Brandt, Mark J; Zeelenberg, Marcel

    2018-03-01

    Individual differences in disgust sensitivity are associated with a range of judgments and attitudes related to the moral domain. Some perspectives suggest that the association between disgust sensitivity and moral judgments will be equally strong across all moral domains (i.e., purity, authority, loyalty, care, fairness, and liberty). Other perspectives predict that disgust sensitivity is primarily associated with judgments of specific moral domains (e.g., primarily purity). However, no study has systematically tested if disgust sensitivity is associated with moral judgments of the purity domain specifically, more generally to moral judgments of the binding moral domains, or to moral judgments of all of the moral domains equally. Across 5 studies (total N = 1,104), we find consistent evidence for the notion that disgust sensitivity relates more strongly to moral condemnation of purity-based transgressions (meta-analytic r = .40) than to moral condemnation of transgressions of any of the other domains (range meta-analytic rs: .07-.27). Our findings are in line with predictions from Moral Foundations Theory, which predicts that personality characteristics like disgust sensitivity make people more sensitive to a certain set of moral issues. (PsycINFO Database Record (c) 2018 APA, all rights reserved).

  5. Primary chondroid chordoma arising from the petrous temporal bone: a case report

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Young Uk; Youn, Eun Kyung [Koryo General Hospital, Seoul (Korea, Republic of)

    1991-01-15

    Chordomas are uncommon tumors which arise from remnants of the primitive notochord. They are situated chiefly in the anterior spinal axis with a predilection for the sacrococcygeal region and the basiocciput. About 50% of chordomas are sacrococcygeal, 35% are intracranial, and 15% arise from a vertebral body. As a histologic variant of chordoma, /chondroid chordoma' was first described by Heffelfinger et al. We present a rare case of primary chondroid chordoma arising from the petrous temporal bone. To our knowledge, only two other cases of this type have been reported earlier.

  6. Primary chondroid chordoma arising from the petrous temporal bone: a case report

    International Nuclear Information System (INIS)

    Lee, Young Uk; Youn, Eun Kyung

    1991-01-01

    Chordomas are uncommon tumors which arise from remnants of the primitive notochord. They are situated chiefly in the anterior spinal axis with a predilection for the sacrococcygeal region and the basiocciput. About 50% of chordomas are sacrococcygeal, 35% are intracranial, and 15% arise from a vertebral body. As a histologic variant of chordoma, /chondroid chordoma' was first described by Heffelfinger et al. We present a rare case of primary chondroid chordoma arising from the petrous temporal bone. To our knowledge, only two other cases of this type have been reported earlier

  7. Solution of adsorption problems involving steep moving profiles

    DEFF Research Database (Denmark)

    Kiil, Søren; Bhatia, Suresh K.

    1998-01-01

    The moving finite element collocation method proposed by Kiil et al. (1995) for solution of problems with steep gradients is further developed to solve transient problems arising in the field of adsorption. The technique is applied to a model of adsorption in solids with bidisperse pore structures....... Numerical solutions were found to match the analytical solution when it exists (i.e. when the adsorption isotherm is linear). Results of this application study show that the method is simple yet sufficiently accurate for use in adsorption problems with steep moving gradients, where global collocation...

  8. Parallel algorithms for network routing problems and recurrences

    International Nuclear Information System (INIS)

    Wisniewski, J.A.; Sameh, A.H.

    1982-01-01

    In this paper, we consider the parallel solution of recurrences, and linear systems in the regular algebra of Carre. These problems are equivalent to solving the shortest path problem in graph theory, and they also arise in the analysis of Fortran programs. Our methods for solving linear systems in the regular algebra are analogues of well-known methods for solving systems of linear algebraic equations. A parallel version of Dijkstra's method, which has no linear algebraic analogue, is presented. Considerations for choosing an algorithm when the problem is large and sparse are also discussed

  9. Color Vision Deficiency and Color Blindness: An Introduction to the Problem.

    Science.gov (United States)

    Olsen, Mary Margaret; Harris, Kenneth R.

    The paper examines issues concerned with the education and employment of individuals, primarily males, with color vision deficiency. After a brief introduction, the first chapter looks at adult problems such as employment areas in which the disability presents problems. The next chapter considers problems of children, noting the heavy use of color…

  10. Nonlinear diffusion problem arising in plasma physics

    International Nuclear Information System (INIS)

    Berryman, J.G.; Holland, C.J.

    1978-01-01

    In earlier studies of plasma diffusion with Okuda-Dawson scaling (D approx. n/sup -1/2/), perturbation theory indicated that arbitrary initial data should evolve rapidly toward the separation solution of the relevant nonlinear diffusion equation. Now a Lyapunov functional has been found which is strictly decreasing in time and bounded below. The rigorous proof that arbitrary initial data evolve toeard the separable solution is summarized. Rigorous bounds on the decay time are also presented

  11. Elasto-plastic torsion problem as an infinity Laplace's equation

    Directory of Open Access Journals (Sweden)

    Ahmed Addou

    2006-12-01

    Full Text Available In this paper, we study a perturbed infinity Laplace's equation, the perturbation corresponds to an Leray-Lions operator with no coercivity assumption. We consider the case where data are distributions or $L^{1}$ elements. We show that this problem has an unique solution which is the solution to the variational inequality arising in the elasto-plastic torsion problem, associated with an operator $A$.

  12. A parameter identification problem arising from a two-dimensional airfoil section model

    International Nuclear Information System (INIS)

    Cerezo, G.M.

    1994-01-01

    The development of state space models for aeroelastic systems, including unsteady aerodynamics, is particularly important for the design of highly maneuverable aircraft. In this work we present a state space formulation for a special class of singular neutral functional differential equations (SNFDE) with initial data in C(-1, 0). This work is motivated by the two-dimensional airfoil model presented by Burns, Cliff and Herdman in. In the same authors discuss the validity of the assumptions under which the model was formulated. They pay special attention to the derivation of the evolution equation for the circulation on the airfoil. This equation was coupled to the rigid-body dynamics of the airfoil in order to obtain a complete set of functional differential equations that describes the composite system. The resulting mathematical model for the aeroelastic system has a weakly singular component. In this work we consider a finite delay approximation to the model presented in. We work with a scalar model in which we consider the weak singularity appearing in the original problem. The main goal of this work is to develop numerical techniques for the identification of the parameters appearing in the kernel of the associated scalar integral equation. Clearly this is the first step in the study of parameter identification for the original model and the corresponding validation of this model for the aeroelastic system

  13. The CANDU-PHW generating system waste arisings

    International Nuclear Information System (INIS)

    Simmons, G.R.

    1979-03-01

    In this report, the volume of material and level of contained radioactive nuclides are tabulated for wastes arising from four fuel cycles which might be operated in CANDU-PHW (CANada Deuterium Uranium - Pressurized Heavy Water) reactors. The data presented, based on Canadian experience and/or studies, cover the range of conditioned waste volumes which could be expected from steady-state (no growth), CANDU-PHW-powered electrical generating systems. The wastes arising from operation and decommissioning of facilities in each phase of each fuel cycle are estimated. Each fuel cycle is considered to operate in isolation with the data given in terms of quantities per gigawatt-year of electricity produced. Three of the fuel cycles for which data are presented, the natural uranium once-through cycle, the plutonium-enriched uranium cycle (plutonium recycle) and the low-burnup uranium-enriched thorium cycle (thorium and uranium recycle), were studied by INFCE WG.7 (the International Nuclear Fuel Cycle Evaluation, Working Group 7) as fuel cycles 4, 5 and 6. The high-burnup uranium-enriched thorium cycle is included for comparison. INFCE WG.7 selected many common reference parameters which are applied uniformly to all seven INFCE WG.7 reference fuel cycles in determining waste arisings. Where these parameters differ from the data of Canadian origin given in the body of this report, the INFCE WG.7 data are given in an appendix. The waste management costs associated with operation of each INFCE WG.7 reference fuel cycle were calculated and compared by the working group. An arbitrary set of costing parameters and disposal technologies was selected by the working group for application to each of the reference fuel cycles. The waste management and disposal costs for the PHW reactor fuel cycles based on these arbitrary cost parameters are given in an appendix. (author)

  14. Squamous cell carcinoma arising within a maxillary odontogenic keratocyst: A rare occurrence

    International Nuclear Information System (INIS)

    Jalali, Elnaz; Tadinada, Aditya; Rengasamy, Kandasamy; Ferneini, Elie M.

    2017-01-01

    Squamous cell carcinoma (SCC) arising within the lining of an odontogenic keratocyst (OKC) is a rare occurrence. Although potentially locally destructive, OKC is a benign odontogenic process that typically presents with clinical and radiographic features characteristic of a benign intraosseous neoplasm. We present the clinical and radiographic features of a maxillary mass that demonstrated SCC arising from the lining of an OKC. Although the initial clinical and radiographic presentation suggested an infection or malignant neoplasm, biopsies revealed an infiltrative well-differentiated SCC contiguous with and arising from the focus of a pre-existing OKC. The patient subsequently underwent a type II hemi-maxillectomy with neoadjuvant chemoradiation. This report discusses the clinical and radiographic features associated with intraosseous malignancies, especially those arising from an otherwise benign odontogenic lesion. While the majority of OKCs are benign, the current report illustrates the potential for carcinomatous transformation within the lining of an OKC

  15. Squamous cell carcinoma arising within a maxillary odontogenic keratocyst: A rare occurrence

    Energy Technology Data Exchange (ETDEWEB)

    Jalali, Elnaz [Eliray Oral and Maxillofacial Radiology Consulting Services, Miami (United States); Tadinada, Aditya; Rengasamy, Kandasamy; Ferneini, Elie M. [University of Connecticut, School of Dental Medicine, Farmington (United States)

    2017-06-15

    Squamous cell carcinoma (SCC) arising within the lining of an odontogenic keratocyst (OKC) is a rare occurrence. Although potentially locally destructive, OKC is a benign odontogenic process that typically presents with clinical and radiographic features characteristic of a benign intraosseous neoplasm. We present the clinical and radiographic features of a maxillary mass that demonstrated SCC arising from the lining of an OKC. Although the initial clinical and radiographic presentation suggested an infection or malignant neoplasm, biopsies revealed an infiltrative well-differentiated SCC contiguous with and arising from the focus of a pre-existing OKC. The patient subsequently underwent a type II hemi-maxillectomy with neoadjuvant chemoradiation. This report discusses the clinical and radiographic features associated with intraosseous malignancies, especially those arising from an otherwise benign odontogenic lesion. While the majority of OKCs are benign, the current report illustrates the potential for carcinomatous transformation within the lining of an OKC.

  16. Chemistry and the Internal Combustion Engine II: Pollution Problems.

    Science.gov (United States)

    Hunt, C. B.

    1979-01-01

    Discusses pollution problems which arise from the use of internal combustion (IC) engines in the United Kingdom (UK). The IC engine exhaust emissions, controlling IC engine pollution in the UK, and some future developments are also included. (HM)

  17. Computing the full spectrum of large sparse palindromic quadratic eigenvalue problems arising from surface Green's function calculations

    Science.gov (United States)

    Huang, Tsung-Ming; Lin, Wen-Wei; Tian, Heng; Chen, Guan-Hua

    2018-03-01

    Full spectrum of a large sparse ⊤-palindromic quadratic eigenvalue problem (⊤-PQEP) is considered arguably for the first time in this article. Such a problem is posed by calculation of surface Green's functions (SGFs) of mesoscopic transistors with a tremendous non-periodic cross-section. For this problem, general purpose eigensolvers are not efficient, nor is advisable to resort to the decimation method etc. to obtain the Wiener-Hopf factorization. After reviewing some rigorous understanding of SGF calculation from the perspective of ⊤-PQEP and nonlinear matrix equation, we present our new approach to this problem. In a nutshell, the unit disk where the spectrum of interest lies is broken down adaptively into pieces small enough that they each can be locally tackled by the generalized ⊤-skew-Hamiltonian implicitly restarted shift-and-invert Arnoldi (G⊤SHIRA) algorithm with suitable shifts and other parameters, and the eigenvalues missed by this divide-and-conquer strategy can be recovered thanks to the accurate estimation provided by our newly developed scheme. Notably the novel non-equivalence deflation is proposed to avoid as much as possible duplication of nearby known eigenvalues when a new shift of G⊤SHIRA is determined. We demonstrate our new approach by calculating the SGF of a realistic nanowire whose unit cell is described by a matrix of size 4000 × 4000 at the density functional tight binding level, corresponding to a 8 × 8nm2 cross-section. We believe that quantum transport simulation of realistic nano-devices in the mesoscopic regime will greatly benefit from this work.

  18. Predictors of moderated drinking in a primarily alcohol dependent sample of men who have sex with men

    Science.gov (United States)

    Kuerbis, Alexis; Morgenstern, Jon; Hail, Lisa

    2012-01-01

    Understanding for whom moderated drinking is a viable, achievable, and sustainable goal among those with a range of alcohol use disorders (AUD) remains an important public health question. Despite common acceptance as severe risk factors, there is little empirical evidence to conclude whether co-occurring mental health disorders or drug dependence contribute to an individual’s inability to successfully moderate his drinking. Utilizing secondary data analysis, the purpose of this study was to identify predictors of moderation among both treatment seeking and non-treatment seeking, primarily alcohol dependent, problem drinking men who have sex with men (MSM), with an emphasis on the high risk factors psychiatric comorbidity and drug dependence. Problem drinkers (N=187) were assessed, provided feedback about their drinking, given the option to receive brief AUD treatment or change their drinking on their own, and then followed for 15 months. Findings revealed that neither psychiatric comorbidity or drug dependence predicted ability to achieve moderation when controlling for alcohol dependence severity. Those who were younger, more highly educated, and had more mild alcohol dependence were more likely to achieve moderated drinking. Impact of treatment on predictors is explored. Limitations of this study and arenas for future research are discussed. PMID:22201219

  19. Primarily Experimental Results for a W Wire Array Z Pinch

    International Nuclear Information System (INIS)

    Kuai Bin; Aici, Qiu; Wang Liangping; Zeng Zhengzhong; Wang Wensheng; Cong Peitian; Gai Tongyang; Wei Fuli; Guo Ning; Zhang Zhong

    2006-01-01

    Primarily experimental results are given for a W wire array Z pinch imploded with up to 2 MA in 100 ns on a Qiangguang-I pulsed power generator. The configuration and parameters of the generator, the W wire array load assembly and the diagnostic system for the experiment are described. The total X-ray energy has been obtained with a averaged power of X-ray radiation of 1.28 TW

  20. Satellite communications: possibilities and problems

    International Nuclear Information System (INIS)

    Hine, M.

    1986-01-01

    Communication links via satellites are becoming available in Europe, both as part of the development of the telephone system and as special services aimed at data traffic. They offer the possibility of speeds between 50 kb/s and 2 Mb/s, without the problems and long term commitments of long distance land lines. Such links are provided by the PTT's as circuits which can be booked for variable periods, and have error rates which can be very low and well controlled. Problems in networking can arise from the satellite delay, particularly if errors occur in the local connections, and from the leased circuit and tariff philosophies of the PTT's. (Auth.)

  1. Convergence of Cell Based Finite Volume Discretizations for Problems of Control in the Conduction Coefficients

    DEFF Research Database (Denmark)

    Evgrafov, Anton; Gregersen, Misha Marie; Sørensen, Mads Peter

    2011-01-01

    We present a convergence analysis of a cell-based finite volume (FV) discretization scheme applied to a problem of control in the coefficients of a generalized Laplace equation modelling, for example, a steady state heat conduction. Such problems arise in applications dealing with geometric optimal......, whereas the convergence of the coefficients happens only with respect to the "volumetric" Lebesgue measure. Additionally, depending on whether the stationarity conditions are stated for the discretized or the original continuous problem, two distinct concepts of stationarity at a discrete level arise. We...... provide characterizations of limit points, with respect to FV mesh size, of globally optimal solutions and two types of stationary points to the discretized problems. We illustrate the practical behaviour of our cell-based FV discretization algorithm on a numerical example....

  2. An efficient heuristic for the multi-compartment vehicle routing problem

    OpenAIRE

    Paulo Vitor Silvestrin

    2016-01-01

    We study a variant of the vehicle routing problem that allows vehicles with multiple compartments. The need for multiple compartments frequently arises in practical applications when there are several products of different quality or type, that must be kept or handled separately. The resulting problem is called the multi-compartment vehicle routing problem (MCVRP). We propose a tabu search heuristic and embed it into an iterated local search to solve the MCVRP. In several experiments we analy...

  3. Nuclear energy centers: Economic and environmental problems

    International Nuclear Information System (INIS)

    Dollezhal', N.A.; Bobolovich, V.N.; Emel'yanov, I.Ya.; Kochenov, A.S.; Koryakin, Yu.I.; Stolyarevskij, A.Ya.; Chernyaev, V.A.; Ponomarev-Stepnoj, N.N.; Protsenko, A.M.

    1977-01-01

    The report deals with qualitative and quantitative analysis of factors and problems, which may arise in the nearest future with the dispersion of sites of nuclear and fuel cycle plants. These problems arise with a large increase in the transportation of radioactive nuclear fuel, the necessity in valuable land and water resources, delay in construction and scheduled commercial operation of nuclear power plant, increase in the cost of labour and other economic and environmental factors and limitations. The report has an analysis of one of the ways of decreasing these difficulties, connected with the construction of large nuclear energy centres, consisting of a cluster of reactors on a single reactor site with the combined capacity of 40,000-50,000 MWe. The centres may consist, for example, of a cluster of conventional nuclear power plants that mainly consist of fast breeders and fuel cycle plants. They should be located in regions with a low density population and low value and deficiency of land and water resources. Electricity will be transmitted to consumers. The social-economic functions of such centres as factors that give birth to industrial regions are considered. Also given is the comparative estimate of benefits and problems of these two ways of further development of nuclear power system [ru

  4. The Cauchy problem for the Pavlov equation

    Science.gov (United States)

    Grinevich, P. G.; Santini, P. M.; Wu, D.

    2015-10-01

    Commutation of multidimensional vector fields leads to integrable nonlinear dispersionless PDEs that arise in various problems of mathematical physics and have been intensively studied in recent literature. This report aims to solve the scattering and inverse scattering problem for integrable dispersionless PDEs, recently introduced just at a formal level, concentrating on the prototypical example of the Pavlov equation, and to justify an existence theorem for global bounded solutions of the associated Cauchy problem with small data. An essential part of this work was made during the visit of the three authors to the Centro Internacional de Ciencias in Cuernavaca, Mexico in November-December 2012.

  5. Combined algorithms in nonlinear problems of magnetostatics

    International Nuclear Information System (INIS)

    Gregus, M.; Khoromskij, B.N.; Mazurkevich, G.E.; Zhidkov, E.P.

    1988-01-01

    To solve boundary problems of magnetostatics in unbounded two- and three-dimensional regions, we construct combined algorithms based on a combination of the method of boundary integral equations with the grid methods. We study the question of substantiation of the combined method of nonlinear magnetostatic problem without the preliminary discretization of equations and give some results on the convergence of iterative processes that arise in non-linear cases. We also discuss economical iterative processes and algorithms that solve boundary integral equations on certain surfaces. Finally, examples of numerical solutions of magnetostatic problems that arose when modelling the fields of electrophysical installations are given too. 14 refs.; 2 figs.; 1 tab

  6. On Helmholtz Problem for Plane Periodical Structures

    International Nuclear Information System (INIS)

    Akishin, P.G.; Vinitskij, S.I.

    1994-01-01

    The plane Helmholtz problem of the periodical disc structures with the phase shifts conditions of the solutions along the basis lattice vectors and the Dirichlet conditions on the basic boundaries is considered. The Green function satisfying the quasi periodical conditions on the lattice is constructed. The Helmholtz problem is reduced to the boundary integral equations for the simple layer potentials of this Green function. The methods of the discretization of the arising integral equations are proposed. The procedures of calculation of the matrix elements are discussed. The reality of the spectral parameter of the nonlinear continuous and discretized problems is shown. 8 refs., 2 figs

  7. Help-seeking for early childhood mental health problems

    OpenAIRE

    Oh, Elizabeth

    2017-01-01

    Children's mental health has significant implications for functioning across home, school, and community settings. The infant to preschool years has been found to be a crucial stage in a child’s development. As such, problems that arise during these years are likely to impact a child’s social and emotional development if no treatment is sought. Childhood mental health problems affect up to almost one quarter of children globally (Belfer, 2008; Canino, Bird, Rubio-Stipec, & Bravo, 1995; Egger ...

  8. Malignancy arising within cutaneous tattoos: case of dermatofibrosarcoma protuberans and review of literature.

    Science.gov (United States)

    Reddy, Kavitha K; Hanke, C William; Tierney, Emily P

    2011-08-01

    Dermatofibrosarcoma protuberans (DFSP) is an uncommon tumor of the skin with high rates of local recurrence. Several reports describe a frequent history of local trauma. In one prior case, a DFSP arising in a tattoo site has been reported. Mohs micrographic surgery (MMS) has been used successfully for treatment. To present a case of dermatofibrosarcoma protuberans arising in the site of a prior and current tattoo, and treated with Mohs micrographic surgery. We present findings of a case of a DFSP arising in a tattoo and a review of Medline literature on the association between tattoos and cutaneous malignancy, and treatment of DFSP with MMS. Review of the literature confirms multiple reports of DFSP arising in sites of local trauma, as well as malignancies arising in sites of tattoos. The recurrence rate for MMS treatment of DFSP (0-6.6%) was found to be significantly lower than that for patients treated with wide local excision (13% to 95%). DFSP should be considered in the differential diagnosis of neoplasms arising within areas of tattoos. Sites of local trauma and tattoos may show predilection for benign and malignant changes and should be evaluated during regular skin exams. Review of the literature confirms MMS is an ideal treatment modality for DFSP as the tumor often extends far beyond clinical margins.

  9. An Inventory-Routing Problem with Pickups and Deliveries Arising in the Replenishment of Automated Teller Machines

    NARCIS (Netherlands)

    van Anholt, Roel G.; Coelho, Leandro C.; Laporte, Gilbert; Vis, Iris F. A.

    The purpose of this paper is to introduce, model, and solve a rich multiperiod inventory-routing problem with pickups and deliveries motivated by the replenishment of automated teller machines in the Netherlands. Commodities can be brought to and from the depot, as well as being exchanged among

  10. An inventory-routing problem with pickups and deliveries arising in the replenishment of automated teller machines

    NARCIS (Netherlands)

    Van Anholt, Roel G.; Coelho, Leandro C.; Laporte, Gilbert; Vis, Iris F.A.

    2016-01-01

    The purpose of this paper is to introduce, model, and solve a rich multiperiod inventory-routing problem with pickups and deliveries motivated by the replenishment of automated teller machines in the Netherlands. Commodities can be brought to and from the depot, as well as being exchanged among

  11. Atomic policies: history, problems

    International Nuclear Information System (INIS)

    Galvan, Cesare Giuseppe.

    1993-01-01

    Two kinds of problems follow from the development of nuclear technology: its use in (diversion to) armaments, and its dangers for the population. Both arise as social phenomena: technology can be diverted to military aims; and installations require specific measures in order not to expose human life to danger. The diffusion of this technology required a series of tentative solutions for such problems. Its history constitutes our first part. The second part aims at understanding the dynamics, which led to the diffusion of such a technology in the capitalist world. The concept of subsumption (especially of its realization) is suited to interpret the meanings of the social interests, which led content ro this diffusion. Subsumption is found between labor and capital, but also between society and state. At both levels, it shows that there was some social meaning in the diffusion of nuclear technology notwithstanding its problems. 590 refs

  12. Two cases of basal cell carcinoma arising from chronic radiation dermatitis

    International Nuclear Information System (INIS)

    Wakamori, Takeshi; Takenaka, Hideya; Ueda, Eiichiro; Katoh, Norito; Kishimoto, Saburo

    2003-01-01

    A 48-year-old female and a 51-year-old male with basal cell carcinoma (BCC) arising from chronic radiation dermatitis are reviewed. They are treated with radiotherapy for hemangioma on their right cheek in their childhood. Review in the literature showed high incidence of the histological diagnosis of malignant skin tumors arising from chronic radiation dermatitis are follows: squamous cell carcinoma (SCC), BCC, sarcoma, and Bowen's disease. (author)

  13. To the development of numerical methods in problems of radiation transport

    International Nuclear Information System (INIS)

    Germogenova, T.A.

    1990-01-01

    Review of studies on the development of numerical methods and the discrete ordinate method in particular, used for solution of radiation protection physics problems is given. Consideration is given to the problems, which arise when calculating fields of penetrating radiation and when studying processes of charged-particle transport and cascade processes, generated by high-energy primary radiation

  14. Classical limit of the quantum inverse scattering problem

    International Nuclear Information System (INIS)

    Bogdanov, I.V.

    1986-01-01

    This paper studies the passage to the limit of classical mechanics which is realized in the formalism of Marchenko's method for a spherically symmetric inverse problem of quantum scattering for fixed angular momentum. The limit is considered for the general case of partial waves with arbitrary values of the orbital number 1>0 in the lowest order of perturbation theory. It is shown how in the limit h→0 in the quantum inverse problem the integral Able transformation characteristic of classical inverse problems arises. The classical inversion formula with delay time is derived from the Marchenko equation

  15. Closed nuclear facilities in Estonia: developments and problems

    International Nuclear Information System (INIS)

    Realo, E.; Realo, K.

    2000-01-01

    At present Estonia has no operating nuclear or a radioactive material production facility. As a legacy of the past the country has become responsible for the decommissioning of two large nuclear cycle facilities of the former USSR. Besides limited funding, major problems arise from deficiencies in legislation, expertise, training and research. International co-operation has been of immense importance to overcome the problems, to establish the national radiation protection and radioactive waste management infrastructure and to launch decommissioning and remediation activities. An overview is given on the status and problems. Copyright (2000) Australasian Radiation Protection Society Inc

  16. "Alea Iacta Est" (a case series report of problem and pathological gambling).

    Science.gov (United States)

    Koić, Elvira; Filaković, Pavo; Djordjević, Veljko; Nadj, Sanea

    2009-09-01

    Gambling or gaming is a common term for a group of various games, activities and behavior that involve wagering money on an event with an uncertain outcome with the primary intent of winning additional money, i.e., a player risks and hopes to get back what he/she had gambled, or to win more. When the player is unable to resist impulses to gamble, and gambling behavior harmfully affects him or the others, then he/she is suffering from the so called "pathological gambling", which is one of six categories of the "Impulse control disorders" in the International Classification of Diseases. Since, at present, there is no standardized program and approach to the problem of gambling in Croatia, and having in mind the arising accessibility and popularity of the "games of chance", the authors are presenting seven cases of problem and pathological gambling and call for broad public discussion on the problem from medical-psychiatric and forensic-point of view. The first patient was treated on an outpatient basis with cognitive-behavioral and family therapy for problem gambling; for the second patient was treated for impulse control disorders; for the third patient gambling was a symptom of psychotic form of depressive disorder; the fourth had primary diagnosis of personality disorder; and the fifth patient was prosecuted for armed robbery and evaluated by a psychiatric expert. The sixth and the seventh patients were women suffering from primary bipolar affective and major depressive disorder, respectively. The authors conclude that, due to the size of the problem and its consequences, the prevention of pathological gambling is very important. The prevention can be carried out primarily through screening at the school level and primary health care services, whereas secondary screening may be conducted through the system of psychiatric care. It is recommended to invest into research, education of a wider population, and development of preventive programs.

  17. A fast nonlinear conjugate gradient based method for 3D frictional contact problems

    NARCIS (Netherlands)

    Zhao, J.; Vollebregt, E.A.H.; Oosterlee, C.W.

    2014-01-01

    This paper presents a fast numerical solver for a nonlinear constrained optimization problem, arising from a 3D frictional contact problem. It incorporates an active set strategy with a nonlinear conjugate gradient method. One novelty is to consider the tractions of each slip element in a polar

  18. Hilbert's seventh problem solutions and extensions

    CERN Document Server

    Tubbs, Robert

    2016-01-01

    This exposition is primarily a survey of the elementary yet subtle innovations of several mathematicians between 1929 and 1934 that led to partial and then complete solutions to Hilbert’s Seventh Problem (from the International Congress of Mathematicians in Paris, 1900). This volume is suitable for both mathematics students, wishing to experience how different mathematical ideas can come together to establish results, and for research mathematicians interested in the fascinating progression of mathematical ideas that solved Hilbert’s problem and established a modern theory of transcendental numbers. .

  19. Optimal recombination in genetic algorithms for combinatorial optimization problems: Part II

    Directory of Open Access Journals (Sweden)

    Eremeev Anton V.

    2014-01-01

    Full Text Available This paper surveys results on complexity of the optimal recombination problem (ORP, which consists in finding the best possible offspring as a result of a recombination operator in a genetic algorithm, given two parent solutions. In Part II, we consider the computational complexity of ORPs arising in genetic algorithms for problems on permutations: the Travelling Salesman Problem, the Shortest Hamilton Path Problem and the Makespan Minimization on Single Machine and some other related problems. The analysis indicates that the corresponding ORPs are NP-hard, but solvable by faster algorithms, compared to the problems they are derived from.

  20. A fast nonlinear conjugate gradient based method for 3D concentrated frictional contact problems

    NARCIS (Netherlands)

    J. Zhao (Jing); E.A.H. Vollebregt (Edwin); C.W. Oosterlee (Cornelis)

    2015-01-01

    htmlabstractThis paper presents a fast numerical solver for a nonlinear constrained optimization problem, arising from 3D concentrated frictional shift and rolling contact problems with dry Coulomb friction. The solver combines an active set strategy with a nonlinear conjugate gradient method. One

  1. Applying Cooperative Techniques in Teaching Problem Solving

    Directory of Open Access Journals (Sweden)

    Krisztina Barczi

    2013-12-01

    Full Text Available Teaching how to solve problems – from solving simple equations to solving difficult competition tasks – has been one of the greatest challenges for mathematics education for many years. Trying to find an effective method is an important educational task. Among others, the question arises as to whether a method in which students help each other might be useful. The present article describes part of an experiment that was designed to determine the effects of cooperative teaching techniques on the development of problem-solving skills.

  2. Advanced Research Workshop on Nonlinear Hyperbolic Problems

    CERN Document Server

    Serre, Denis; Raviart, Pierre-Arnaud

    1987-01-01

    The field of nonlinear hyperbolic problems has been expanding very fast over the past few years, and has applications - actual and potential - in aerodynamics, multifluid flows, combustion, detonics amongst other. The difficulties that arise in application are of theoretical as well as numerical nature. In fact, the papers in this volume of proceedings deal to a greater extent with theoretical problems emerging in the resolution of nonlinear hyperbolic systems than with numerical methods. The volume provides an excellent up-to-date review of the current research trends in this area.

  3. Reflections on the surface energy imbalance problem

    Science.gov (United States)

    Ray Leuning; Eva van Gorsela; William J. Massman; Peter R. Isaac

    2012-01-01

    The 'energy imbalance problem' in micrometeorology arises because at most flux measurement sites the sum of eddy fluxes of sensible and latent heat (H + λE) is less than the available energy (A). Either eddy fluxes are underestimated or A is overestimated. Reasons for the imbalance are: (1) a failure to satisfy the fundamental assumption of one-...

  4. A natural solution to the μ-problem in supergravity theories

    International Nuclear Information System (INIS)

    Giudice, G.F.; Masiero, A.

    1988-01-01

    We propose a 'natural' way to avoid the introduction by hand of a small mass scale μ in the observable sector of N=1 supergravity theories. In our approach, μ automatically arises from the general couplings of broken supergravity. In this way, all low energy mass parameters arise only from supergravity breaking and, in particular, SU(2)xU(1) is left unbroken in the limit of exact supersymmetry. Our solution of the μ-problem presents interesting connections with the strong CP puzzle through the implementation of symmetries a la Peccei and Quinn. (orig.)

  5. Solving Large Scale Crew Scheduling Problems in Practice

    NARCIS (Netherlands)

    E.J.W. Abbink (Erwin); L. Albino; T.A.B. Dollevoet (Twan); D. Huisman (Dennis); J. Roussado; R.L. Saldanha

    2010-01-01

    textabstractThis paper deals with large-scale crew scheduling problems arising at the Dutch railway operator, Netherlands Railways (NS). NS operates about 30,000 trains a week. All these trains need a driver and a certain number of guards. Some labor rules restrict the duties of a certain crew base

  6. About some types of constraints in problems of routing

    Science.gov (United States)

    Petunin, A. A.; Polishuk, E. G.; Chentsov, A. G.; Chentsov, P. A.; Ukolov, S. S.

    2016-12-01

    Many routing problems arising in different applications can be interpreted as a discrete optimization problem with additional constraints. The latter include generalized travelling salesman problem (GTSP), to which task of tool routing for CNC thermal cutting machines is sometimes reduced. Technological requirements bound to thermal fields distribution during cutting process are of great importance when developing algorithms for this task solution. These requirements give rise to some specific constraints for GTSP. This paper provides a mathematical formulation for the problem of thermal fields calculating during metal sheet thermal cutting. Corresponding algorithm with its programmatic implementation is considered. The mathematical model allowing taking such constraints into account considering other routing problems is discussed either.

  7. Clinical outcomes of patients with clear cell and endometrioid ovarian cancer arising from endometriosis.

    Science.gov (United States)

    Paik, E Sun; Kim, Tae Joong; Choi, Chel Hun; Kim, Byoung Gie; Bae, Duk Soo; Lee, Jeong Won

    2018-03-01

    The aim of this investigation is to compare outcomes of patients according to the presence of cancer arising from endometriosis in ovarian clear cell carcinoma (CCC) and endometrioid carcinoma (EC). This study retrospectively investigated 224 CCC and EC patients treated in Samsung Medical Center from 2001 to 2015 to identify cancer arising from endometriosis according to Sampson and Scott criteria. Propensity score matching was performed to compare patients arising from endometriosis to patients without endometriosis (ratio 1:1) according to stage, age, lymph node metastasis (LNM), cancer antigen (CA)-125 level, and residual status after debulking surgery. Forty-five cases arising from endometriosis were compared with 179 cases without endometriosis. CCC and EC arising from endometriosis tended to present with early age (mean, 45.2 vs. 49.2 years; p=0.003), early-stage (stages I and II, 92.7% vs. 62.3%; p<0.001), lower CA-125 level (mean, 307.1 vs. 556.7; p=0.041), higher percentages of no gross residual disease after surgery (87.8% vs.56.8%; p=0.001), and higher percentages of negative LNM (82.9% vs. 59.0%; p=0.008) compared to cases without endometriosis. Kaplan-Meier curves for progression-free survival (PFS) and overall survival (OS) showed better outcomes for groups with cancer arising from endometriosis (p=0.014 for PFS; and p=0.010 for OS). However, the association with endometriosis was not significant in multivariate analysis. Also, after propensity score matching, survival differences between the 2 groups were not significant. CCC and EC arising from endometriosis are diagnosed at an earlier age and stage. However, cancer arising from endometriosis was not a significant prognostic factor. Copyright © 2018. Asian Society of Gynecologic Oncology, Korean Society of Gynecologic Oncology

  8. The Australasian Resuscitation in Sepsis Evaluation (ARISE) trial statistical analysis plan.

    Science.gov (United States)

    Delaney, Anthony P; Peake, Sandra L; Bellomo, Rinaldo; Cameron, Peter; Holdgate, Anna; Howe, Belinda; Higgins, Alisa; Presneill, Jeffrey; Webb, Steve

    2013-09-01

    The Australasian Resuscitation in Sepsis Evaluation (ARISE) study is an international, multicentre, randomised, controlled trial designed to evaluate the effectiveness of early goal-directed therapy compared with standard care for patients presenting to the emergency department with severe sepsis. In keeping with current practice, and considering aspects of trial design and reporting specific to non-pharmacological interventions, our plan outlines the principles and methods for analysing and reporting the trial results. The document is prepared before completion of recruitment into the ARISE study, without knowledge of the results of the interim analysis conducted by the data safety and monitoring committee and before completion of the two related international studies. Our statistical analysis plan was designed by the ARISE chief investigators, and reviewed and approved by the ARISE steering committee. We reviewed the data collected by the research team as specified in the study protocol and detailed in the study case report form. We describe information related to baseline characteristics, characteristics of delivery of the trial interventions, details of resuscitation, other related therapies and other relevant data with appropriate comparisons between groups. We define the primary, secondary and tertiary outcomes for the study, with description of the planned statistical analyses. We have developed a statistical analysis plan with a trial profile, mock-up tables and figures. We describe a plan for presenting baseline characteristics, microbiological and antibiotic therapy, details of the interventions, processes of care and concomitant therapies and adverse events. We describe the primary, secondary and tertiary outcomes with identification of subgroups to be analysed. We have developed a statistical analysis plan for the ARISE study, available in the public domain, before the completion of recruitment into the study. This will minimise analytical bias and

  9. Lower Limb Injuries Arising From Motorcycle Crashes | Kortor ...

    African Journals Online (AJOL)

    Background: Motorcycle accidents are the second most common cause of road traffic accidents in both developing and developed countries. In this study we aim to look at the pattern and characteristics of lower limb injuries arising from motorcycle accidents and evaluate early outcome of treatment. Methods: All the patients ...

  10. On time-dependent diffusion coefficients arising from stochastic processes with memory

    Science.gov (United States)

    Carpio-Bernido, M. Victoria; Barredo, Wilson I.; Bernido, Christopher C.

    2017-08-01

    Time-dependent diffusion coefficients arise from anomalous diffusion encountered in many physical systems such as protein transport in cells. We compare these coefficients with those arising from analysis of stochastic processes with memory that go beyond fractional Brownian motion. Facilitated by the Hida white noise functional integral approach, diffusion propagators or probability density functions (pdf) are obtained and shown to be solutions of modified diffusion equations with time-dependent diffusion coefficients. This should be useful in the study of complex transport processes.

  11. Stieltjes electrostatic model interpretation for bound state problems

    Indian Academy of Sciences (India)

    In this paper, it is shown that Stieltjes electrostatic model and quantum Hamilton Jacobi formalism are analogous to each other. This analogy allows the bound state problem to mimic as unit moving imaginary charges i ℏ , which are placed in between the two fixed imaginary charges arising due to the classical turning ...

  12. Counting in Lattices: Combinatorial Problems from Statistical Mechanics.

    Science.gov (United States)

    Randall, Dana Jill

    In this thesis we consider two classical combinatorial problems arising in statistical mechanics: counting matchings and self-avoiding walks in lattice graphs. The first problem arises in the study of the thermodynamical properties of monomers and dimers (diatomic molecules) in crystals. Fisher, Kasteleyn and Temperley discovered an elegant technique to exactly count the number of perfect matchings in two dimensional lattices, but it is not applicable for matchings of arbitrary size, or in higher dimensional lattices. We present the first efficient approximation algorithm for computing the number of matchings of any size in any periodic lattice in arbitrary dimension. The algorithm is based on Monte Carlo simulation of a suitable Markov chain and has rigorously derived performance guarantees that do not rely on any assumptions. In addition, we show that these results generalize to counting matchings in any graph which is the Cayley graph of a finite group. The second problem is counting self-avoiding walks in lattices. This problem arises in the study of the thermodynamics of long polymer chains in dilute solution. While there are a number of Monte Carlo algorithms used to count self -avoiding walks in practice, these are heuristic and their correctness relies on unproven conjectures. In contrast, we present an efficient algorithm which relies on a single, widely-believed conjecture that is simpler than preceding assumptions and, more importantly, is one which the algorithm itself can test. Thus our algorithm is reliable, in the sense that it either outputs answers that are guaranteed, with high probability, to be correct, or finds a counterexample to the conjecture. In either case we know we can trust our results and the algorithm is guaranteed to run in polynomial time. This is the first algorithm for counting self-avoiding walks in which the error bounds are rigorously controlled. This work was supported in part by an AT&T graduate fellowship, a University of

  13. Squamous cell carcinoma arising in previously burned or irradiated skin

    International Nuclear Information System (INIS)

    Edwards, M.J.; Hirsch, R.M.; Broadwater, J.R.; Netscher, D.T.; Ames, F.C.

    1989-01-01

    Squamous cell carcinoma (SCC) arising in previously burned or irradiated skin was reviewed in 66 patients treated between 1944 and 1986. Healing of the initial injury was complicated in 70% of patients. Mean interval from initial injury to diagnosis of SCC was 37 years. The overwhelming majority of patients presented with a chronic intractable ulcer in previously injured skin. The regional relapse rate after surgical excision was very high, 58% of all patients. Predominant patterns of recurrence were in local skin and regional lymph nodes (93% of recurrences). Survival rates at 5, 10, and 20 years were 52%, 34%, and 23%, respectively. Five-year survival rates in previously burned and irradiated patients were not significantly different (53% and 50%, respectively). This review, one of the largest reported series, better defines SCC arising in previously burned or irradiated skin as a locally aggressive disease that is distinct from SCC arising in sunlight-damaged skin. An increased awareness of the significance of chronic ulceration in scar tissue may allow earlier diagnosis. Regional disease control and survival depend on surgical resection of all known disease and may require radical lymph node dissection or amputation

  14. A problem of finding an acceptable variant in generalized project networks

    Directory of Open Access Journals (Sweden)

    David Blokh

    2005-01-01

    Full Text Available A project network often has some activities or groups of activities which can be performed at different stages of the project. Then, the problem of finding an optimal/acceptable time or/and optimal/acceptable order of such an activity or a group of activities arises. Such a problem emerges, in particular, in house-building management when the beginnings of some activities may vary in time or/and order. We consider a mathematical formulation of the problem, show its computational complexity, and describe an algorithm for solving the problem.

  15. The single-sink fixed-charge transportation problem: Applications and solution methods

    DEFF Research Database (Denmark)

    Goertz, Simon; Klose, Andreas

    2007-01-01

    The single-sink fixed-charge transportation problem (SSFCTP) consists in finding a minimum cost flow from a number of supplier nodes to a single demand node. Shipping costs comprise costs proportional to the amount shipped as well as a fixed-charge. Although the SSFCTP is an important special case...... of the well-known fixed-charge transportation problem, just a few methods for solving this problem have been proposed in the literature. After summarising some applications of this problem arising in manufacturing and transportation, we give an overview on approximation algorithms and worst-case results...

  16. Bayesian inverse problems for functions and applications to fluid mechanics

    International Nuclear Information System (INIS)

    Cotter, S L; Dashti, M; Robinson, J C; Stuart, A M

    2009-01-01

    In this paper we establish a mathematical framework for a range of inverse problems for functions, given a finite set of noisy observations. The problems are hence underdetermined and are often ill-posed. We study these problems from the viewpoint of Bayesian statistics, with the resulting posterior probability measure being defined on a space of functions. We develop an abstract framework for such problems which facilitates application of an infinite-dimensional version of Bayes theorem, leads to a well-posedness result for the posterior measure (continuity in a suitable probability metric with respect to changes in data), and also leads to a theory for the existence of maximizing the posterior probability (MAP) estimators for such Bayesian inverse problems on function space. A central idea underlying these results is that continuity properties and bounds on the forward model guide the choice of the prior measure for the inverse problem, leading to the desired results on well-posedness and MAP estimators; the PDE analysis and probability theory required are thus clearly dileneated, allowing a straightforward derivation of results. We show that the abstract theory applies to some concrete applications of interest by studying problems arising from data assimilation in fluid mechanics. The objective is to make inference about the underlying velocity field, on the basis of either Eulerian or Lagrangian observations. We study problems without model error, in which case the inference is on the initial condition, and problems with model error in which case the inference is on the initial condition and on the driving noise process or, equivalently, on the entire time-dependent velocity field. In order to undertake a relatively uncluttered mathematical analysis we consider the two-dimensional Navier–Stokes equation on a torus. The case of Eulerian observations—direct observations of the velocity field itself—is then a model for weather forecasting. The case of

  17. Anaplastic ganglioglioma arising from a Lhermitte-Duclos-like lesion. Case report.

    Science.gov (United States)

    Takei, Hidehiro; Dauser, Robert; Su, Jack; Chintagumpala, Murali; Bhattacharjee, Meenakshi B; Jones, Jeremy; Adesina, Adekunle M

    2007-08-01

    The authors report the case of a 7-year-old boy with a history of developmental delay who presented with aggressive behavior. A magnetic resonance (MR) image showed a mass lesion originating from the cerebellar vermis with an atypical folial pattern and contrast enhancement. Histologically, the subtotally resected specimen consisted mostly of neuropil with nodular foci of ganglion cells. Lhermitte-Duclos disease (LDD) was diagnosed in the patient. A retrospective review of the tissue sections showed a nidus of associated astrocytic proliferation, suggesting a diagnosis of ganglioglioma. Five years later, the patient experienced an altered mental state and a facial droop. An MR image revealed a cerebellar mass with cystic areas and an enhancing nodule. The resected tissue specimen consisted primarily of a mixed proliferation of glial and ganglion cells consistent with a ganglioglioma. Two years later, a third craniectomy was performed in the patient for worsening headache and ataxia. Histologically, the tumor showed progressive anaplasia and was most accurately classified as an anaplastic ganglioglioma. Immunohistochemically, most of the tumor cells were immunoreactive for anti-phospho-mammalian target of rapamycin (mTOR) and phospho-S6 ribosomal protein antibodies. In contrast, the subpopulation of neoplastic ganglion cells in the tissue, particularly from the first surgery, did not express phosphatase and tensin homolog deleted from chromosome 10 (PTEN). This immunohistochemical pattern suggests that the large dysplastic ganglion cells (the gangliocytomatous component) forming the greater part of the lesion were associated with activation of the phosphatidylinositol 3-kinase-PTEN/Akt/mTOR signaling pathway, a feature previously reported in LDD. This case represents the first report of an anaplastic ganglioglioma arising in an LDD-like lesion.

  18. Solitary osteochondroma arising in lumbar spinous process: Case report

    Directory of Open Access Journals (Sweden)

    Khaled Hadhri

    2016-12-01

    Full Text Available Solitary osteochondromas rarely occur in the axial skeleton. Those tumors mostly arise on the posterior elements of the cervical column causing various symptoms especially when developing within the spinal canal. Exophytic lumbar variety is uncommon presenting with palpable mass or spinal deformity. We report a 20-year-old man presenting with a solid painless mass at the lower lumbar region. Radiological examinations revealed an exophytic lesion arising in the third lumbar spinous process appearing to be a solitary osteochondroma. The lesion was treated by en-bloc resection; histopathological examination confirmed the diagnosis of osteochondroma with no evidence of recurrence at the end of 2-year follow up.

  19. Optimization methods for the Train Unit Shunting Problem

    DEFF Research Database (Denmark)

    Haahr, Jørgen Thorlund; Lusby, Richard Martin; Wagenaar, Joris Camiel

    2017-01-01

    We consider the Train Unit Shunting Problem, an important planning problem for passenger railway operators. This problem entails assigning train units from shunting yards to scheduled train services in such a way that the resulting operations are without conflicts. The problem arises at every...... shunting yard in the railway network and involves matching train units to arriving and departing train services as well as assigning the selected matchings to appropriate shunting yard tracks. We present an extensive comparison benchmark of multiple solution approaches for this problem, some of which...... are novel. In particular, we develop a constraint programming formulation, a column generation approach, and a randomized greedy heuristic. We compare and benchmark these approaches with two existing methods, a mixed integer linear program and a two-stage heuristic. The benchmark contains multiple real...

  20. Decision Analysis on Survey and SOil Investigation Problem in Power Engineering Consultant

    OpenAIRE

    Setyaman, Amy Maulany; Sunitiyoso, Yos

    2013-01-01

    The study aims to gather and organize information for decision making against the problems arising in Power Engineering Consultant's survey and soil investigation product due to new policy in production cost efficiency that is implemented in 2012. The study conducted using Kepner and Tragoe's analytical process that consisted of four stages analytical process such as situation analysis, problem analysis, decision making analysis and potential problem analysis. As for the decision making analy...

  1. Post-transplant Lymphoproliferative Disorder Arising from Renal Allograft Parenchyma: A Case Report

    Energy Technology Data Exchange (ETDEWEB)

    Park, Byung Kwan; Kim, Chan Kyo; Kwon, Ghee Young [Samsung Medical Center, Sungkyunkwan University College of Medicine, Seoul (Korea, Republic of)

    2010-06-15

    Post-transplant lymphoproliferative disorder (PTLD) is a rare but serious complication that occurs in patients undergoing kidney transplantation. PTLD usually manifests as a renal hilar mass comprised of histologically B-lymphocytes. We report our experience of managing a patient with PTLD arising from renal parenchyma. Ultrasonographic and MR imaging features of this unusual PTLD suggested differentiated renal cell carcinoma arising from the renal allograft

  2. What is physics problem solving competency?

    DEFF Research Database (Denmark)

    Niss, Martin

    2018-01-01

    on the nature of physics problem- solving competency. The first, Sommerfeld’s, is a “theory first, phenomenon second” approach. Here the relevant problems originate in one of the theories of physics and the job goal of the problem- solver is to make a mathematical analysis of the suitable equation......A central goal of physics education is to teach problem-solving competency, but the nature of this competency is not well-described in the literature. The present paperarticle uses recent historical scholarship on Arnold Sommerfeld and Enrico Fermi to identify and characterize two positions......(s) and then give a qualitative analysis of the phenomenon that arise from these mathematical results. Fermi’s position is a “phenomenon first, theory second” approach, where the starting point is a physical phenomenon that is analyzed and then brought into the realm of a physics theory. The two positions...

  3. Closed solutions to a differential-difference equation and an associated plate solidification problem.

    Science.gov (United States)

    Layeni, Olawanle P; Akinola, Adegbola P; Johnson, Jesse V

    2016-01-01

    Two distinct and novel formalisms for deriving exact closed solutions of a class of variable-coefficient differential-difference equations arising from a plate solidification problem are introduced. Thereupon, exact closed traveling wave and similarity solutions to the plate solidification problem are obtained for some special cases of time-varying plate surface temperature.

  4. Constructing Student Problems in Phylogenetic Tree Construction.

    Science.gov (United States)

    Brewer, Steven D.

    Evolution is often equated with natural selection and is taught from a primarily functional perspective while comparative and historical approaches, which are critical for developing an appreciation of the power of evolutionary theory, are often neglected. This report describes a study of expert problem-solving in phylogenetic tree construction.…

  5. Security risks arising from portable storage devices

    CSIR Research Space (South Africa)

    Molotsi, K

    2012-10-01

    Full Text Available of the security risks arising from the use of PSDs, and further provides possible security countermeasures to help organisations and users to protect their digital assets. APPROACH Literature review: ? To investigate security risks posed by PSDs... technology in the workplace. International Journal of Electronic Security and Digital Forensics. 3(1): 73?81 [3] Kim, K., Kim, E. & Hong S. (2009). Privacy information protection in portable device. Proceedings of International Conference on Convergence...

  6. The indeterminate rate problem for birth-death processes

    NARCIS (Netherlands)

    van Doorn, Erik A.

    1987-01-01

    A birth-death process is completely determined by its set of rates if and only if this set satisfies a certain condition C, say. If for a set of rates R the condition C is not fulfilled, then the problem arises of characterizing all birth-death processes which have rate set R (the indeterminate rate

  7. Philosophy of river problems: local to regional, static to mobile

    International Nuclear Information System (INIS)

    Jansky, L.

    1997-01-01

    According to the statistics, thirteen of the twenty-five major river basins in Europe are basins of transboundary rivers. The Danube river basin is largest transboundary river basin in Europe. Almost in each case the local and regional problems arise, like division of fishing rights (or rights on river beds), right to claim tolls on navigation, how to adjust boundaries if the channel moves, or rights to claim duty on crossing the river, or to build bridges, weirs, etc. All the above problems on a larger scale include also rights of non-contiguous lands (i.e. not fronting on the river) to use the river for navigation, for passage of migrating fish, to exploit river (e.g. bed sediments) without damage by one country or society to another below. Similarly, pollution and large-scale removal of water, are problems on regional or national levels. Disputes usually arise from the above, more or less exacerbated by their superimposition or other non-river problems, e.g. religion, politics, historical issues, recent aggression, relative prosperity, expanding economy vs. contrasting economy. May be cause or consequence of many of these. And somewhere here is likely the case of Gabcikovo on Danube between Slovakia and Hungary, as well. (author)

  8. Problems in mathematical analysis III integration

    CERN Document Server

    Kaczor, W J

    2003-01-01

    We learn by doing. We learn mathematics by doing problems. This is the third volume of Problems in Mathematical Analysis. The topic here is integration for real functions of one real variable. The first chapter is devoted to the Riemann and the Riemann-Stieltjes integrals. Chapter 2 deals with Lebesgue measure and integration. The authors include some famous, and some not so famous, integral inequalities related to Riemann integration. Many of the problems for Lebesgue integration concern convergence theorems and the interchange of limits and integrals. The book closes with a section on Fourier series, with a concentration on Fourier coefficients of functions from particular classes and on basic theorems for convergence of Fourier series. The book is primarily geared toward students in analysis, as a study aid, for problem-solving seminars, or for tutorials. It is also an excellent resource for instructors who wish to incorporate problems into their lectures. Solutions for the problems are provided in the boo...

  9. Mathematical problems in meteorological modelling

    CERN Document Server

    Csomós, Petra; Faragó, István; Horányi, András; Szépszó, Gabriella

    2016-01-01

    This book deals with mathematical problems arising in the context of meteorological modelling. It gathers and presents some of the most interesting and important issues from the interaction of mathematics and meteorology. It is unique in that it features contributions on topics like data assimilation, ensemble prediction, numerical methods, and transport modelling, from both mathematical and meteorological perspectives. The derivation and solution of all kinds of numerical prediction models require the application of results from various mathematical fields. The present volume is divided into three parts, moving from mathematical and numerical problems through air quality modelling, to advanced applications in data assimilation and probabilistic forecasting. The book arose from the workshop “Mathematical Problems in Meteorological Modelling” held in Budapest in May 2014 and organized by the ECMI Special Interest Group on Numerical Weather Prediction. Its main objective is to highlight the beauty of the de...

  10. Iterative solution of multiple radiation and scattering problems in structural acoustics using the BL-QMR algorithm

    Energy Technology Data Exchange (ETDEWEB)

    Malhotra, M. [Stanford Univ., CA (United States)

    1996-12-31

    Finite-element discretizations of time-harmonic acoustic wave problems in exterior domains result in large sparse systems of linear equations with complex symmetric coefficient matrices. In many situations, these matrix problems need to be solved repeatedly for different right-hand sides, but with the same coefficient matrix. For instance, multiple right-hand sides arise in radiation problems due to multiple load cases, and also in scattering problems when multiple angles of incidence of an incoming plane wave need to be considered. In this talk, we discuss the iterative solution of multiple linear systems arising in radiation and scattering problems in structural acoustics by means of a complex symmetric variant of the BL-QMR method. First, we summarize the governing partial differential equations for time-harmonic structural acoustics, the finite-element discretization of these equations, and the resulting complex symmetric matrix problem. Next, we sketch the special version of BL-QMR method that exploits complex symmetry, and we describe the preconditioners we have used in conjunction with BL-QMR. Finally, we report some typical results of our extensive numerical tests to illustrate the typical convergence behavior of BL-QMR method for multiple radiation and scattering problems in structural acoustics, to identify appropriate preconditioners for these problems, and to demonstrate the importance of deflation in block Krylov-subspace methods. Our numerical results show that the multiple systems arising in structural acoustics can be solved very efficiently with the preconditioned BL-QMR method. In fact, for multiple systems with up to 40 and more different right-hand sides we get consistent and significant speed-ups over solving the systems individually.

  11. Effects arising from charged particles overcoming of the light velocity barrier

    International Nuclear Information System (INIS)

    Afanas'ev, G.N.; Eliseev, S.M.; Stepanovskij, Yu.P.

    1997-01-01

    The effects arising from accelerated and decelerated motion of the charged point particle inside the medium are studied. It is shown explicitly that in addition to the Bremsstrahlung and Cherenkov shock wave, the electromagnetic shock wave arising from the charge overcoming the light velocity in the medium should be observed. This shock wave has the same singularity as the Cherenkov one and, therefore, it is more singular than the Bremsstrahlung shock wave. The space-time regions where these shock waves exist and conditions under which they appear are determined

  12. Adenocarcinomas arising from primary retroperitoneal mature teratomas: CT and MR imaging

    International Nuclear Information System (INIS)

    Wang, Li-Jen; Wong, Yon-Cheong; Chu, Sheng-Hsien; Ng, Kwai-Fong

    2002-01-01

    An adenocarcinoma arising from mature teratoma is one form of teratoma with malignant transformation. It is extremely rare but highly malignant. The authors report two patients with adenocarcinomas arising from primary retroperitoneal teratomas. The CT and MRI findings of the tumors are presented with emphasis on imaging features implying the presence of malignant transformation and differing from those of pure benign mature teratoma. Correct diagnosis of the presence of malignant transformation from a benign mature teratoma can be made as early as possible by awareness of the imaging features. (orig.)

  13. Ecknomic benefits arising from the Canadian nuclear industry

    International Nuclear Information System (INIS)

    1982-03-01

    This document is a collection of surveys of the Canadian nuclear industry, with forecasts covering a number of possible scenarios. Topics covered include uranium mining and processing; economic benefits arising from the design, manufacture and construction of CANDU generating stations; employment and economic activity in the Canadian nqclear industry; and an overview of the remainder of the industry

  14. Similarities of discrete and continuous Sturm-Liouville problems

    Directory of Open Access Journals (Sweden)

    Kazem Ghanbari

    2007-12-01

    Full Text Available In this paper we present a study on the analogous properties of discrete and continuous Sturm-Liouville problems arising in matrix analysis and differential equations, respectively. Green's functions in both cases have analogous expressions in terms of the spectral data. Most of the results associated to inverse problems in both cases are identical. In particular, in both cases Weyl's m-function determines the Sturm-Liouville operators uniquely. Moreover, the well known Rayleigh-Ritz Theorem in linear algebra can be proved by using the concept of Green's function in discrete case.

  15. Transoral videolaryngoscopic surgery for papillary carcinoma arising in lingual thyroid.

    Science.gov (United States)

    Mogi, Chisato; Shinomiya, Hirotaka; Fujii, Natsumi; Tsuruta, Tomoyuki; Morita, Naruhiko; Furukawa, Tatsuya; Teshima, Masanori; Kanzawa, Maki; Hirokawa, Mitsuyoshi; Otsuki, Naoki; Nibu, Ken-Ichi

    2018-05-15

    Carcinoma arising in lingual thyroid is an extremely rare entity accounting for only 1% of all reported ectopic thyroids. Here, we report a case of carcinoma arising in lingual thyroid, which has been successfully managed by transoral resection and bilateral neck dissections. A lingual mass 4-cm in diameter with calcification was incidentally detected by computed tomography at medical check-up. No thyroid tissue was observed in normal position. Ultrasound examination showed bilateral multiple lymphadenopathies. Fine needle aspiration biopsy from lymph node in his right neck was diagnosed as Class III and thyroglobulin level of the specimen was 459ng/ml. Due to the difficulty in performing FNA of the lingual masses, right neck dissection was performed in advance for diagnostic purpose. Pathological examination showed existence of large and small follicular thyroid tissues in several lymph nodes, suggesting lymph node metastasis from thyroid carcinoma. Two months after the initial surgery, video-assisted transoral resection of lingual thyroid with simultaneous left neck dissection was performed. Postoperative course was uneventful. Papillary carcinoma was found in the lingual thyroid and thyroid tissues were also found in left cervical lymph nodes. Video-assisted transoral resection was useful for the treatment of thyroid cancer arising in lingual thyroid. Copyright © 2018 Elsevier B.V. All rights reserved.

  16. Mucinous adenocarcinoma arising at the anastomotic site after operation for hirschsprung's disease: case report

    International Nuclear Information System (INIS)

    Kim, Hyung Soo; Yoon, Kwon Ha

    2004-01-01

    To our knowledge, rectal cancer arising at the anastomotic site after surgery for Hirschsprung's disease has not been reported. We report a case of mucinous adenocarcinoma arising at the anastomotic site after Soave operation 26 years ago

  17. Some open problems in the physics of disordered systems

    Indian Academy of Sciences (India)

    Some problems in the physics of disordered systems are pointed out; most of these arise from experiments. Keywords. Disordered systems; electron localization; metal insulator transitions. PACS Nos 71.55. .... overlapping the free electron Fermi sphere, the Fermi surface is cut up into a large number of small electron and ...

  18. Infinite-horizon optimal control problems in economics

    International Nuclear Information System (INIS)

    Aseev, Sergei M; Besov, Konstantin O; Kryazhimskii, Arkadii V

    2012-01-01

    This paper extends optimal control theory to a class of infinite-horizon problems that arise in studying models of optimal dynamic allocation of economic resources. In a typical problem of this sort the initial state is fixed, no constraints are imposed on the behaviour of the admissible trajectories at large times, and the objective functional is given by a discounted improper integral. We develop the method of finite-horizon approximations in a broad context and use it to derive complete versions of the Pontryagin maximum principle for such problems. We provide sufficient conditions for the normality of infinite-horizon optimal control problems and for the validity of the 'standard' limit transversality conditions with time going to infinity. As a meaningful example, we consider a new two-sector model of optimal economic growth subject to a random jump in prices. Bibliography: 53 titles.

  19. Radiologic findings of malignant tumors arising from ovarian endometriosis

    International Nuclear Information System (INIS)

    Lee, Eun Ju; Joo, Hee Jae; Kim, Bo Hyun

    1999-01-01

    To determine the radiologic characteristics of malignant tumors arising from ovarian endometriosis. The radiologic findings of eleven patients with pelvic masses histologically confirmed as malignant ovarian tumors arising from endometriosis were retrospectively reviewed. All patients underwent MR, and six underwent ultrasonography. The findings were evaluated with regard to tumor size and shape, locularity, thickness and enhancement of the wall and septa, the presence of papillary nodule or solid portion, signal intensity of the locule, the presence of mass in contralateral ovary, ascites, local invasion, distant metastases, and the Pathologic diagnosis included clear cell carcinoma in six cases, endometrioid carcinoma in three, and mucinous cystadenocarcinoma of borderline malignancy and endometrial stromal sarcoma in one case each. Tumor size ranged from 8 to 20 (mean, 12.7)cm. The tumors were mixed in four cases, entirely cystic in three, predominantly cystic in three, and predominantly solid in one. Six cases were unilocular and five were multilocular. The wall and septa varied in thickness and regularity and were well enhanced in all but one case. In all cases papillary nodules or solid portions with similar enhancement to uterine myometrium were seen. On T1WI, the signal intensity of fluid was seen to be high in eight cases, low or intermediate in two, and of differing intensity in one. Ten cases showed high signal intensity on T2WI, whereas in one case in which high signal intensity was seen on T1WI, there was low signal intensity(shading). In three cases the contralateral ovary contained an endometrioma. Other features included ascites in seven cases and peritoneal seeding in one. Malignant ovarian tumors arising from endometriosis showed radiologic features of malignancy:they were larger than 10cm, there was enhancement of the wall and septa, and a papillary nodule or solid portion was present. However, the presence of hyperintense fluid, as seen on T1WI

  20. Radiologic findings of malignant tumors arising from ovarian endometriosis

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Eun Ju; Joo, Hee Jae [Ajou Univ. College of Medicine, Suwon (Korea, Republic of); Kim, Bo Hyun [SungkyunKwan Univ. College of Medicine, Seoul (Korea, Republic of)

    1999-11-01

    To determine the radiologic characteristics of malignant tumors arising from ovarian endometriosis. The radiologic findings of eleven patients with pelvic masses histologically confirmed as malignant ovarian tumors arising from endometriosis were retrospectively reviewed. All patients underwent MR, and six underwent ultrasonography. The findings were evaluated with regard to tumor size and shape, locularity, thickness and enhancement of the wall and septa, the presence of papillary nodule or solid portion, signal intensity of the locule, the presence of mass in contralateral ovary, ascites, local invasion, distant metastases, and the Pathologic diagnosis included clear cell carcinoma in six cases, endometrioid carcinoma in three, and mucinous cystadenocarcinoma of borderline malignancy and endometrial stromal sarcoma in one case each. Tumor size ranged from 8 to 20 (mean, 12.7)cm. The tumors were mixed in four cases, entirely cystic in three, predominantly cystic in three, and predominantly solid in one. Six cases were unilocular and five were multilocular. The wall and septa varied in thickness and regularity and were well enhanced in all but one case. In all cases papillary nodules or solid portions with similar enhancement to uterine myometrium were seen. On T1WI, the signal intensity of fluid was seen to be high in eight cases, low or intermediate in two, and of differing intensity in one. Ten cases showed high signal intensity on T2WI, whereas in one case in which high signal intensity was seen on T1WI, there was low signal intensity(shading). In three cases the contralateral ovary contained an endometrioma. Other features included ascites in seven cases and peritoneal seeding in one. Malignant ovarian tumors arising from endometriosis showed radiologic features of malignancy:they were larger than 10cm, there was enhancement of the wall and septa, and a papillary nodule or solid portion was present. However, the presence of hyperintense fluid, as seen on T1WI

  1. Existence and nonexistence results for a singular boundary value problem arising in the theory of epitaxial growth

    Czech Academy of Sciences Publication Activity Database

    Escudero, C.; Hakl, Robert; Peral, I.; Torres, P.J.

    2014-01-01

    Roč. 37, č. 6 (2014), s. 793-807 ISSN 0170-4214 Institutional support: RVO:67985840 Keywords : singular boundary value problem * epitaxial growth * radial solution Subject RIV: BA - General Mathematics Impact factor: 0.918, year: 2014 http://onlinelibrary.wiley.com/doi/10.1002/mma.2836/full

  2. Human punishment is not primarily motivated by inequality.

    Science.gov (United States)

    Marczyk, Jesse

    2017-01-01

    Previous theorizing about punishment has suggested that humans desire to punish inequality per se. However, the research supporting such an interpretation contains important methodological confounds. The main objective of the current experiment was to remove those confounds in order to test whether generating inequality per se is punished. Participants were recruited from an online market to take part in a wealth-alteration game with an ostensible second player. The participants were given an option to deduct from the other player's payment as punishment for their behavior during the game. The results suggest that human punishment does not appear to be motivated by inequality per se, as inequality that was generated without inflicting costs on others was not reliably punished. Instead, punishment seems to respond primarily to the infliction of costs, with inequality only becoming relevant as a secondary input for punishment decisions. The theoretical significance of this finding is discussed in the context of its possible adaptive value.

  3. Human punishment is not primarily motivated by inequality

    Science.gov (United States)

    Marczyk, Jesse

    2017-01-01

    Previous theorizing about punishment has suggested that humans desire to punish inequality per se. However, the research supporting such an interpretation contains important methodological confounds. The main objective of the current experiment was to remove those confounds in order to test whether generating inequality per se is punished. Participants were recruited from an online market to take part in a wealth-alteration game with an ostensible second player. The participants were given an option to deduct from the other player’s payment as punishment for their behavior during the game. The results suggest that human punishment does not appear to be motivated by inequality per se, as inequality that was generated without inflicting costs on others was not reliably punished. Instead, punishment seems to respond primarily to the infliction of costs, with inequality only becoming relevant as a secondary input for punishment decisions. The theoretical significance of this finding is discussed in the context of its possible adaptive value. PMID:28187166

  4. Human punishment is not primarily motivated by inequality.

    Directory of Open Access Journals (Sweden)

    Jesse Marczyk

    Full Text Available Previous theorizing about punishment has suggested that humans desire to punish inequality per se. However, the research supporting such an interpretation contains important methodological confounds. The main objective of the current experiment was to remove those confounds in order to test whether generating inequality per se is punished. Participants were recruited from an online market to take part in a wealth-alteration game with an ostensible second player. The participants were given an option to deduct from the other player's payment as punishment for their behavior during the game. The results suggest that human punishment does not appear to be motivated by inequality per se, as inequality that was generated without inflicting costs on others was not reliably punished. Instead, punishment seems to respond primarily to the infliction of costs, with inequality only becoming relevant as a secondary input for punishment decisions. The theoretical significance of this finding is discussed in the context of its possible adaptive value.

  5. Vragov’s boundary value problem for an implicit equation of mixed type

    Science.gov (United States)

    Egorov, I. E.

    2017-10-01

    We study a Vragov boundary value problem for a third-order implicit equation of mixed type with an arbitrary manifold of type switch. These Sobolev-type equations arise in many important applied problems. Given certain constraints on the coefficients and the right-hand side of the equation, we demonstrate, using nonstationary Galerkin method and regularization method, the unique regular solvability of the boundary value problem. We also obtain an error estimate for approximate solutions of the boundary value problem in terms of the regularization parameter and the eigenvalues of the Dirichlet spectral problem for the Laplace operator.

  6. Spinal cord injury arising in anaesthesia practice.

    Science.gov (United States)

    Hewson, D W; Bedforth, N M; Hardman, J G

    2018-01-01

    Spinal cord injury arising during anaesthetic practice is a rare event, but one that carries a significant burden in terms of morbidity and mortality. In this article, we will review the pathophysiology of spinal cord injury. We will then discuss injuries relating to patient position, spinal cord hypoperfusion and neuraxial techniques. The most serious causes of spinal cord injury - vertebral canal haematoma, spinal epidural abscess, meningitis and adhesive arachnoiditis - will be discussed in turn. For each condition, we draw attention to practical, evidence-based measures clinicians can undertake to reduce their incidence, or mitigate their severity. Finally, we will discuss transient neurological symptoms. Some cases of spinal cord injury during anaesthesia can be ascribed to anaesthesia itself, arising as a direct consequence of its conduct. The injury to a spinal nerve root by inaccurate and/or incautious needling during spinal anaesthesia is an obvious example. But in many cases, spinal cord injury during anaesthesia is not caused by, related to, or even associated with, the conduct of the anaesthetic. Surgical factors, whether direct (e.g. spinal nerve root damage due to incorrect pedicle screw placement) or indirect (e.g. cord ischaemia following aortic surgery) are responsible for a significant proportion of spinal cord injuries that occur concurrently with the delivery of regional or general anaesthesia. © 2018 The Association of Anaesthetists of Great Britain and Ireland.

  7. Parameter estimation and inverse problems

    CERN Document Server

    Aster, Richard C; Thurber, Clifford H

    2005-01-01

    Parameter Estimation and Inverse Problems primarily serves as a textbook for advanced undergraduate and introductory graduate courses. Class notes have been developed and reside on the World Wide Web for faciliting use and feedback by teaching colleagues. The authors'' treatment promotes an understanding of fundamental and practical issus associated with parameter fitting and inverse problems including basic theory of inverse problems, statistical issues, computational issues, and an understanding of how to analyze the success and limitations of solutions to these probles. The text is also a practical resource for general students and professional researchers, where techniques and concepts can be readily picked up on a chapter-by-chapter basis.Parameter Estimation and Inverse Problems is structured around a course at New Mexico Tech and is designed to be accessible to typical graduate students in the physical sciences who may not have an extensive mathematical background. It is accompanied by a Web site that...

  8. Transboundary environmental problems in international politics

    International Nuclear Information System (INIS)

    Goerrissen, T.

    1993-01-01

    Transboundary environmental problems with their far-reaching consequences impinge on vital interests of the affected countries. As states interdepend not only ecologically but also, or even primarily, economically, environmental problems usually engender a clash between ecological and economic interests. Although economic power is central to getting one's way, economically powerful states by no means always succeed in realising their aims. This topical monograph deals with the subject of regional and global debates and conflicts about transboundary environmental problems. The author points out the prerequisites for realising ecological interests in conditions of complex interdependence, illustrating his findings with two case studies. One is about the establishment of a regime for climate protection, while the other concerns the new ruling on transalpine commercial road transport. (orig./HP) [de

  9. Paradox in a non-linear capacitated transportation problem

    Directory of Open Access Journals (Sweden)

    Dahiya Kalpana

    2006-01-01

    Full Text Available This paper discusses a paradox in fixed charge capacitated transportation problem where the objective function is the sum of two linear fractional functions consisting of variables costs and fixed charges respectively. A paradox arises when the transportation problem admits of an objective function value which is lower than the optimal objective function value, by transporting larger quantities of goods over the same route. A sufficient condition for the existence of a paradox is established. Paradoxical range of flow is obtained for any given flow in which the corresponding objective function value is less than the optimum value of the given transportation problem. Numerical illustration is included in support of theory.

  10. Solitary osteochondroma arising in lumbar spinous process: Case report.

    Science.gov (United States)

    Hadhri, Khaled; Tebourbi, Anis; Saidi, Mehdi; Kooli, Mondher

    2016-12-01

    Solitary osteochondromas rarely occur in the axial skeleton. Those tumors mostly arise on the posterior elements of the cervical column causing various symptoms especially when developing within the spinal canal. Exophytic lumbar variety is uncommon presenting with palpable mass or spinal deformity. We report a 20-year-old man presenting with a solid painless mass at the lower lumbar region. Radiological examinations revealed an exophytic lesion arising in the third lumbar spinous process appearing to be a solitary osteochondroma. The lesion was treated by en-bloc resection; histopathological examination confirmed the diagnosis of osteochondroma with no evidence of recurrence at the end of 2-year follow up. Copyright © 2016 Turkish Association of Orthopaedics and Traumatology. Production and hosting by Elsevier B.V. All rights reserved.

  11. Myoepithelial carcinoma arising within an adenomyoepithelioma of the breast: A case report

    Energy Technology Data Exchange (ETDEWEB)

    Kim, You Yeon; Cho, Kyu Ran; Song, Sung Eun [Dept. of Radiology, Anam Hospital, Korea University College of Medicine, Seoul (Korea, Republic of); Seo, Bo Kyoung [Dept. of Radiology, Ansan Hospital, Korea University College of Medicine, Ansan (Korea, Republic of); Woo, Ok Hee [Dept. of Radiology, Guro Hospital, Korea University College of Medicine, Seoul (Korea, Republic of); Lee, Jeong Hyun [Dept. of Radiology, Anam Hospital, Korea University College of Medicine, Seoul (Korea, Republic of)

    2017-07-15

    Adenomyoepithelioma of the breast is a rare tumor. A myoepithelial carcinoma arising within an adenomyoepithelioma is even more unusual. There are a limited number of reports discussing myoepithelial carcinoma; most of them describe pathological findings, but not imaging findings. We present a case of a 55-year-old woman who had a screen-detected myoepithelial carcinoma arising within an adenomyoepithelioma in her right breast. Upon the completion of a mammography and sonography an oval shaped mass with an indistinct margin in the upper portion of the right breast had been seen. It as appeared to be a spiculated, irregular-shaped, peripheral-enhancing mass on an MRI. On sonography-guided biopsy, an epithelial-myothelial tumor was confirmed, and the possibility of myoepithelial carcinoma was suggested. Breast-conserving surgery with a sentinel lymph node dissection was performed, and a pathological examination revealed a myoepithelial carcinoma arising within an adenomyoepithelioma.

  12. A matrix problem over a discrete valuation ring

    International Nuclear Information System (INIS)

    Zavadskii, A G; Revitskaya, U S

    1999-01-01

    A flat matrix problem of mixed type (over a discrete valuation ring and its skew field of fractions) is considered which naturally arises in connection with several problems in the theory of integer-valued representations and in ring theory. For this problem, a criterion for module boundedness is proved, which is stated in terms of a pair of partially ordered sets (P(A),P(B)) associated with the pair of transforming algebras (A,B) defining the problem. The corresponding statement coincides in effect with the formulation of Kleiner's well-known finite-type criterion for representations of pairs of partially ordered sets over a field. The proof is based on a reduction (which uses the techniques of differentiation) to representations of semimaximal rings (tiled orders) and partially ordered sets

  13. Integrating packing and distribution problems and optimization through mathematical programming

    Directory of Open Access Journals (Sweden)

    Fabio Miguel

    2016-06-01

    Full Text Available This paper analyzes the integration of two combinatorial problems that frequently arise in production and distribution systems. One is the Bin Packing Problem (BPP problem, which involves finding an ordering of some objects of different volumes to be packed into the minimal number of containers of the same or different size. An optimal solution to this NP-Hard problem can be approximated by means of meta-heuristic methods. On the other hand, we consider the Capacitated Vehicle Routing Problem with Time Windows (CVRPTW, which is a variant of the Travelling Salesman Problem (again a NP-Hard problem with extra constraints. Here we model those two problems in a single framework and use an evolutionary meta-heuristics to solve them jointly. Furthermore, we use data from a real world company as a test-bed for the method introduced here.

  14. Enhancing Learners' Problem Solving Performance in Mathematics: A Cognitive Load Perspective

    Science.gov (United States)

    Dhlamini, Joseph J.

    2016-01-01

    This paper reports on a pilot study that investigated the effect of implementing a context-based problem solving instruction (CBPSI) to enhance the problem solving performance of high school mathematics learners. Primarily, the pilot study aimed: (1) to evaluate the efficiency of data collection instruments; and, (2) to test the efficacy of CBPSI…

  15. PROBLEMS OF IT DEPARTMENT IN A MEDICAL UNIVERSITY

    Directory of Open Access Journals (Sweden)

    V. Ya Gelman

    2017-01-01

    Full Text Available The aim of the study is the analysis of the problems faced by heads and staff of IT departments in medical universities. Methodology and research methods. The methods involve expert estimation, analysis and generalization of practical work experience of IT departments. Results and scientific novelty. The main aspects and specifics of professional activity of IT departments of modern medical schools are designated. The approaches to the definition of the hierarchy of goals in the professional activities of the department, as well as quantitative and qualitative indicators that assess the effectiveness of their achievements are analyzed. The contradictions arising between long-term and short-term goals of the IT department are highlighted. The main challenges which heads of IT departments can deal with in the course of day-to-day management work planning are described. The problems arising in educational, educational-methodical and scientific work of department, in its economic activity, solution of personnel affairs, and aspects of material support are considered. The possible solutions to these problems are proposed. Practical significance. The results of the analysis, proposed approaches and practical recommendations will enable to better organize the work of the IT department in a medical school. The advantage of the proposed approaches consists in their versatility: with some adjustment, they can be used by other departments, regardless of the specifics and the type of educational institution.

  16. Poorly Differentiated Squamous Cell Carcinoma Arising in Tattooed Skin

    Science.gov (United States)

    Sarma, Deba P.; Dentlinger, Renee B.; Forystek, Amanda M.; Stevens, Todd; Huerter, Christopher

    2010-01-01

    Introduction. Tattoos have increasingly become accepted by mainstream Western society. As a result, the incidence of tattoo-associated dermatoses is on the rise. The presence of a poorly differentiated squamous cell carcinoma in an old tattooed skin is of interest as it has not been previously documented. Case Presentation. A 79-year-old white homeless man of European descent presented to the dermatology clinic with a painless raised nodule on his left forearm arising in a tattooed area. A biopsy of the lesion revealed a poorly differentiated squamous cell carcinoma infiltrating into a tattoo. The lesion was completely excised and the patient remains disease-free one year later. Conclusion. All previous reports of squamous cell carcinomas arising in tattoos have been well-differentiated low-grade type or keratoacanthoma-type and are considered to be coincidental rather than related to any carcinogenic effect of the tattoo pigments. Tattoo-associated poorly differentiated invasive carcinoma appears to be extremely rare. PMID:21274289

  17. Poorly Differentiated Squamous Cell Carcinoma Arising in Tattooed Skin

    Directory of Open Access Journals (Sweden)

    Deba P. Sarma

    2010-01-01

    Full Text Available Introduction. Tattoos have increasingly become accepted by mainstream Western society. As a result, the incidence of tattoo-associated dermatoses is on the rise. The presence of a poorly differentiated squamous cell carcinoma in an old tattooed skin is of interest as it has not been previously documented. Case Presentation. A 79-year-old white homeless man of European descent presented to the dermatology clinic with a painless raised nodule on his left forearm arising in a tattooed area. A biopsy of the lesion revealed a poorly differentiated squamous cell carcinoma infiltrating into a tattoo. The lesion was completely excised and the patient remains disease-free one year later. Conclusion. All previous reports of squamous cell carcinomas arising in tattoos have been well-differentiated low-grade type or keratoacanthoma-type and are considered to be coincidental rather than related to any carcinogenic effect of the tattoo pigments. Tattoo-associated poorly differentiated invasive carcinoma appears to be extremely rare.

  18. Basal Cell Carcinoma Arising in a Breast Augmentation Scar.

    Science.gov (United States)

    Edwards, Lisa R; Cresce, Nicole D; Russell, Mark A

    2017-04-01

    We report a case of a 46-year-old female who presented with a persistent lesion on the inferior right breast. The lesion was located within the scar from a breast augmentation procedure 12 years ago. The lesion had been treated as several conditions with no improvement. Biopsy revealed a superficial and nodular basal cell carcinoma, and the lesion was successfully removed with Mohs micrographic surgery. Basal cell carcinoma arising in a surgical scar is exceedingly rare with only 13 reported cases to date. This is the first reported case of basal cell carcinoma arising in a breast augmentation scar. We emphasize the importance of biopsy for suspicious lesions or those refractory to treatment, particularly those lesions that form within a scar. Level of Evidence V This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .

  19. Radiological field survey problems and solutions

    International Nuclear Information System (INIS)

    Deming, E.J.; Boerner, A.J.

    1986-01-01

    Situations often arise during radiological field surveys which require the health physicist to improvise and/or make spot decisions. At times these situations can be humorous, but they can also present hazards more serious than normal radiological considerations. This presentation will depict various problematic situations encountered by Oak Ridge Associated Universities Radiological Site Assessment Program in the course of performing field environmental surveys. Detailing these potential hazards can alert other field survey groups to problems they may encounter

  20. Infinite-horizon optimal control problems in economics

    Energy Technology Data Exchange (ETDEWEB)

    Aseev, Sergei M; Besov, Konstantin O; Kryazhimskii, Arkadii V

    2012-04-30

    This paper extends optimal control theory to a class of infinite-horizon problems that arise in studying models of optimal dynamic allocation of economic resources. In a typical problem of this sort the initial state is fixed, no constraints are imposed on the behaviour of the admissible trajectories at large times, and the objective functional is given by a discounted improper integral. We develop the method of finite-horizon approximations in a broad context and use it to derive complete versions of the Pontryagin maximum principle for such problems. We provide sufficient conditions for the normality of infinite-horizon optimal control problems and for the validity of the 'standard' limit transversality conditions with time going to infinity. As a meaningful example, we consider a new two-sector model of optimal economic growth subject to a random jump in prices. Bibliography: 53 titles.

  1. Divorce Rate in the Slovak Republic as a Social and Educational Problem

    Directory of Open Access Journals (Sweden)

    Gežová Katarína Cimprichová

    2016-08-01

    Full Text Available Divorce is considered an unwanted phenomenon in the society, although the divorce rate increases. There are many problems for both sides - parents and their children - coming along with divorce. The legal adjustment of divorce may violently strike not only the lives of children influenced by divorce but also the lives of other persons, whose existence is seriously endangered or complicated by establishing new life conditions. Family break-up and the loss of one parent leaves lifelong consequences on the child. The decision for divorce should be therefore thoroughly considered, because it is the point, where the source of loss of personal and family safety arises. Our aim is to point out the problems arising from divorce not only for the divorcing couple, but also for their children, above all, because divorce should not mean hostility for sensible people, particularly if they have children. It is necessary to find a way how to talk together before and during divorce and to do best in solving problems in the possibly shortest time.

  2. A New Approach to the Container Positioning Problem

    DEFF Research Database (Denmark)

    Ahmt, Jonas; Sigtenbjerggaard, Jonas Skott; Lusby, Richard Martin

    Programming model that not only improves on earlier attempts at this problem, but also better reflects reality. In particular, the proposed model adopts a preference to reshuffle containers in line with a just-in-time concept, as it is assumed that data is more accurate the closer to a container’s scheduled...... for solving larger instances of the problem. We show that this new formulation drastically outperforms previous attempts at the problem through a direct comparison on instances available in the literature. Furthermore, we also show that the rolling horizon based heuristic can further reduce the solution time......In this paper the Container Positioning Problem is revisited. This problem arises at busy container terminals and requires one to minimize the use of block cranes in handling the containers that must wait at the terminal until their next means of transportation. We propose a new Mixed Integer...

  3. Solving the Selective Multi-Category Parallel-Servicing Problem

    DEFF Research Database (Denmark)

    Range, Troels Martin; Lusby, Richard Martin; Larsen, Jesper

    In this paper we present a new scheduling problem and describe a shortest path based heuristic as well as a dynamic programming based exact optimization algorithm to solve it. The Selective Multi-Category Parallel-Servicing Problem (SMCPSP) arises when a set of jobs has to be scheduled on a server...... (machine) with limited capacity. Each job requests service in a prespecified time window and belongs to a certain category. Jobs may be serviced partially, incurring a penalty; however, only jobs of the same category can be processed simultaneously. One must identify the best subset of jobs to process...

  4. Solving the selective multi-category parallel-servicing problem

    DEFF Research Database (Denmark)

    Range, Troels Martin; Lusby, Richard Martin; Larsen, Jesper

    2015-01-01

    In this paper, we present a new scheduling problem and describe a shortest path-based heuristic as well as a dynamic programming-based exact optimization algorithm to solve it. The selective multi-category parallel-servicing problem arises when a set of jobs has to be scheduled on a server (machine......) with limited capacity. Each job requests service in a prespecified time window and belongs to a certain category. Jobs may be serviced partially, incurring a penalty; however, only jobs of the same category can be processed simultaneously. One must identify the best subset of jobs to process in each time...

  5. High grade angiosarcoma arising in fibroadenoma

    Science.gov (United States)

    2011-01-01

    Primary angiosarcoma of the breast is a rare tumour that account for fewer than 0.05% of all malignant mammary tumours. Angiosarcoma may have an perfidious clinical onset. Radiologic findings are often nonspecific and may appear completely normal in one-third of cases with primary angiosarcoma. The prognosis is usually poor because of the high rates of local recurrence and early development of metastases. Aggressive surgical resection is the mainstay of treatment. The role of adjuvant therapy has not yet been well established. Here we present a case of a 53 year old, postmenopausal women with primary angiosarcoma arising in fibroadenoma. To our knowledge, this is the first case described in the literature to date. PMID:22185665

  6. Periorbital nodular fasciitis arising during pregnancy

    Directory of Open Access Journals (Sweden)

    Brandon N Phillips

    2014-01-01

    Full Text Available Nodular fasciitis (NF is a benign proliferation of fibroblasts and myofibroblasts that rarely occurs in the periorbital region. We report what we believe to be the first case of periorbital NF associated with pregnancy. A case of intravascular fasciitis, a NF variant, has been reported during pregnancy, but it was not located in the periorbital region. A weak presence of estrogen receptors has been reported in NF. This may make it more susceptible to the hormone-related changes during pregnancy and contribute to the development of the lesion by stimulating fibroblasts and smooth muscle cell types. Although rare, NF should be considered in the differential diagnosis of periorbital soft-tissue masses arising during pregnancy.

  7. Sound radiation quantities arising from a resilient circular radiator

    NARCIS (Netherlands)

    Aarts, R.M.; Janssen, A.J.E.M.

    2009-01-01

    Power series expansions in ka are derived for the pressure at the edge of a radiator, the reaction force on the radiator, and the total radiated power arising from a harmonically excited, resilient, flat, circular radiator of radius a in an infinite baffle. The velocity profiles on the radiator are

  8. Symmetry of the Adiabatic Condition in the Piston Problem

    Science.gov (United States)

    Anacleto, Joaquim; Ferreira, J. M.

    2011-01-01

    This study addresses a controversial issue in the adiabatic piston problem, namely that of the piston being adiabatic when it is fixed but no longer so when it can move freely. It is shown that this apparent contradiction arises from the usual definition of adiabatic condition. The issue is addressed here by requiring the adiabatic condition to be…

  9. Basal Cell Carcinoma Arising in a Tattooed Eyebrow

    Science.gov (United States)

    Lee, Jong-Sun; Park, Jin; Kim, Seong-Min; Kim, Han-Uk

    2009-01-01

    Malignant skin tumors, including squamous cell carcinoma and malignant melanoma, have occurred in tattoos. Seven documented cases of basal cell carcinoma associated with tattoos have also been reported in the medical literature. We encountered a patient with basal cell carcinoma in a tattooed eyebrow. We report on this case as the eighth reported case of a patient with basal cell carcinoma arising in a tattooed area. PMID:20523804

  10. Budownictwo socjalne na tle zrównoważonego rozwoju miast

    OpenAIRE

    Sikora-Fernandez, Dorota

    2011-01-01

    Social housing has a specific function in the housing stock. It is primarily an instrument used in the system of social assistance, implemented by public authorities. One of the main problems that arise during making decisions about provision of social housing is the problem of localization. Local authorities must answer the question whether it is better to change the destination of the existing housing stock and create social housing within the city, and also derive social ho...

  11. On Newton-Raphson formulation and algorithm for displacement based structural dynamics problem with quadratic damping nonlinearity

    Directory of Open Access Journals (Sweden)

    Koh Kim Jie

    2017-01-01

    Full Text Available Quadratic damping nonlinearity is challenging for displacement based structural dynamics problem as the problem is nonlinear in time derivative of the primitive variable. For such nonlinearity, the formulation of tangent stiffness matrix is not lucid in the literature. Consequently, ambiguity related to kinematics update arises when implementing the time integration-iterative algorithm. In present work, an Euler-Bernoulli beam vibration problem with quadratic damping nonlinearity is addressed as the main source of quadratic damping nonlinearity arises from drag force estimation, which is generally valid only for slender structures. Employing Newton-Raphson formulation, tangent stiffness components associated with quadratic damping nonlinearity requires velocity input for evaluation purpose. For this reason, two mathematically equivalent algorithm structures with different kinematics arrangement are tested. Both algorithm structures result in the same accuracy and convergence characteristic of solution.

  12. The impact of alternate weekly collections on waste arisings

    Energy Technology Data Exchange (ETDEWEB)

    Williams, I.D., E-mail: idw@soton.ac.uk [Waste Management Research Group, Faculty of Engineering and the Environment, Lanchester Building, University of Southampton, University Rd, Highfield, SOUTHAMPTON, Hampshire, SO17 1BJ (United Kingdom); Cole, C. [Centre for Innovative and Collaborative Construction Engineering, School of Civil and Building Engineering, Loughborough University, Epinal Way, Loughborough, LE11 3TU (United Kingdom)

    2013-02-15

    Residual waste is commonly collected separately from recyclable and organic materials. Different forms of collection and disposal are used internationally since regional or municipal authorities have to adapt to their own circumstances. Many authorities have adopted an alternate weekly collection (AWC) of residual waste and recyclables to force/encourage householders to recycle; however, the degree to which they achieve waste reduction has yet to be reliably quantified. This study reports on how the introduction of AWCs affects household waste arisings. The paper evaluates single and dual stream collection methods and compares their performance with the previous system. Household waste collection trials were conducted between March and June 2009 in England (Lichfield). The trials examined changes to frequency of collection, type of container issued, amounts of sorting required of residents, household participation and productivity levels. A survey of households was completed before any changes were implemented. The quantity of recyclates collected was examined for 2008/2009 and 2009/2010. The study showed that the AWC scheme positively impacted on recycling rates and household behaviour, with no adverse impacts on public participation, household waste arisings or the local environment. No public health problems were reported. Both trials saw an increase in the quantities of recyclates collected per household during the trial period compared to the same period of time in the previous year. The dual stream performed better than the single stream, collecting an average of 5.94 kg/hh/week compared to an average of 5.63 kg/hh/week. The single stream system showed a greater increase in the weight of material collected (0.53 kg/hh/week vs. 0.48 kg/hh/week). Participation and set-out rates showed an increase during the trial period. The single stream option (comingled materials in one container) outperformed the dual stream service. The reduction in costs and improved

  13. The impact of alternate weekly collections on waste arisings

    International Nuclear Information System (INIS)

    Williams, I.D.; Cole, C.

    2013-01-01

    Residual waste is commonly collected separately from recyclable and organic materials. Different forms of collection and disposal are used internationally since regional or municipal authorities have to adapt to their own circumstances. Many authorities have adopted an alternate weekly collection (AWC) of residual waste and recyclables to force/encourage householders to recycle; however, the degree to which they achieve waste reduction has yet to be reliably quantified. This study reports on how the introduction of AWCs affects household waste arisings. The paper evaluates single and dual stream collection methods and compares their performance with the previous system. Household waste collection trials were conducted between March and June 2009 in England (Lichfield). The trials examined changes to frequency of collection, type of container issued, amounts of sorting required of residents, household participation and productivity levels. A survey of households was completed before any changes were implemented. The quantity of recyclates collected was examined for 2008/2009 and 2009/2010. The study showed that the AWC scheme positively impacted on recycling rates and household behaviour, with no adverse impacts on public participation, household waste arisings or the local environment. No public health problems were reported. Both trials saw an increase in the quantities of recyclates collected per household during the trial period compared to the same period of time in the previous year. The dual stream performed better than the single stream, collecting an average of 5.94 kg/hh/week compared to an average of 5.63 kg/hh/week. The single stream system showed a greater increase in the weight of material collected (0.53 kg/hh/week vs. 0.48 kg/hh/week). Participation and set-out rates showed an increase during the trial period. The single stream option (comingled materials in one container) outperformed the dual stream service. The reduction in costs and improved

  14. Squamous cell carcinoma arising in a mature cystic teratoma

    Directory of Open Access Journals (Sweden)

    Gupta Vishwanath

    2009-04-01

    Full Text Available Two cases of squamous cell carcinoma (SCC arising in a mature cystic teratoma (MCT are being discussed for their rarity and pattern of infiltration of tumor cells in the stroma (alpha mode, beta mode and gamma mode, which is a key factor in deciding the prognosis and patient survival.

  15. Dynamics of the middle atmosphere as observed by the ARISE project

    Science.gov (United States)

    Blanc, E.

    2015-12-01

    It has been strongly demonstrated that variations in the circulation of the middle atmosphere influence weather and climate all the way to the Earth's surface. A key part of this coupling occurs through the propagation and breaking of planetary and gravity waves. However, limited observations prevent to faithfully reproduce the dynamics of the middle atmosphere in numerical weather prediction and climate models. The main challenge of the ARISE (Atmospheric dynamics InfraStructure in Europe) project is to combine existing national and international observation networks including: the International infrasound monitoring system developed for the CTBT (Comprehensive nuclear-Test-Ban Treaty) verification, the NDACC (Network for the Detection of Atmospheric Composition Changes) lidar network, European observation infrastructures at mid latitudes (OHP observatory), tropics (Maïdo observatory), high latitudes (ALOMAR and EISCAT), infrasound stations which form a dense European network and satellites. The ARISE network is unique by its coverage (polar to equatorial regions in the European longitude sector), its altitude range (from troposphere to mesosphere and ionosphere) and the involved scales both in time (from seconds to tens of years) and space (from tens of meters to thousands of kilometers). Advanced data products are produced with the scope to assimilate data in the Weather Prediction models to improve future forecasts over weeks and seasonal time scales. ARISE observations are especially relevant for the monitoring of extreme events such as thunderstorms, volcanoes, meteors and at larger scales, deep convection and stratospheric warming events for physical processes description and study of long term evolution with climate change. Among the applications, ARISE fosters integration of innovative methods for remote detection of non-instrumented volcanoes including distant eruption characterization to provide notifications with reliable confidence indices to the

  16. Improving Teaching Quality and Problem Solving Ability through Contextual Teaching and Learning in Differential Equations: A Lesson Study Approach

    Science.gov (United States)

    Khotimah, Rita Pramujiyanti; Masduki

    2016-01-01

    Differential equations is a branch of mathematics which is closely related to mathematical modeling that arises in real-world problems. Problem solving ability is an essential component to solve contextual problem of differential equations properly. The purposes of this study are to describe contextual teaching and learning (CTL) model in…

  17. Intraosseous verrucous carcinoma arising from an orthokeratinized odontogenic keratocyst: A report of a rarest entity

    Directory of Open Access Journals (Sweden)

    Nagaraju Kamarthi

    2016-01-01

    Full Text Available Intraosseous verrucous carcinomas (VCs arising from odontogenic cysts are a rare entity. An unusual case of a VC arising from the orthokeratinized odontogenic cyst is described for the first time. The microscopic features of the lesion are presented.

  18. Problems and paradoxes of the Lifshitz theory

    International Nuclear Information System (INIS)

    Klimchitskaya, G L

    2009-01-01

    The problems and paradoxes of the Lifshitz theory in application to real dielectric and semiconductor materials are reviewed. It is shown that the inclusion of drift current of conduction electrons into the model of dielectric response results in contradictions with both thermodynamics and experimental data of different experimental groups. Physical reasons why the problems and paradoxes arise are analyzed and found to be connected with the violation of basic applicability condition of the Lifshitz theory, the thermal equilibrium. A recent alternative approach to the resolution of the problems based on the inclusion of screening effects and diffusion current is considered and demonstrated to be thermodynamically and experimentally inconsistent. It is argued that the inclusion of the diffusion current leads to an even deeper violation of thermal equilibrium. Phenomenologically, the Lifshitz theory with role of drift and diffusion currents neglected is shown to be free of problems and in agreement with both thermodynamics and all available experimental data.

  19. Entanglement witnesses arising from exposed positive linear maps

    OpenAIRE

    Ha, Kil-Chan; Kye, Seung-Hyeok

    2011-01-01

    We consider entanglement witnesses arising from positive linear maps which generate exposed extremal rays. We show that every entanglement can be detected by one of these witnesses, and this witness detects a unique set of entanglement among those. Therefore, they provide a minimal set of witnesses to detect all entanglement in a sense. Furthermore, if those maps are indecomposable then they detect large classes of entanglement with positive partial transposes which have nonempty relative int...

  20. High-Grade Leiomyosarcoma Arising in a Previously Replanted Limb

    Directory of Open Access Journals (Sweden)

    Tiffany J. Pan

    2015-01-01

    Full Text Available Sarcoma development has been associated with genetics, irradiation, viral infections, and immunodeficiency. Reports of sarcomas arising in the setting of prior trauma, as in burn scars or fracture sites, are rare. We report a case of a leiomyosarcoma arising in an arm that had previously been replanted at the level of the elbow joint following traumatic amputation when the patient was eight years old. He presented twenty-four years later with a 10.8 cm mass in the replanted arm located on the volar forearm. The tumor was completely resected and pathology examination showed a high-grade, subfascial spindle cell sarcoma diagnosed as a grade 3 leiomyosarcoma with stage pT2bNxMx. The patient underwent treatment with brachytherapy, reconstruction with a free flap, and subsequently chemotherapy. To the best of our knowledge, this is the first case report of leiomyosarcoma developing in a replanted extremity. Development of leiomyosarcoma in this case could be related to revascularization, scar formation, or chronic injury after replantation. The patient remains healthy without signs of recurrence at three-year follow-up.

  1. Multiple Ectopic Hepatocellular Carcinomas Arising in the Abdominal Cavity

    Directory of Open Access Journals (Sweden)

    Toru Miyake

    2012-09-01

    Full Text Available Ectopic hepatocellular carcinoma (HCC is a very rare clinical entity that is defined as HCC arising from extrahepatic liver tissue. This report presents a case of ectopic multiple HCC arising in the abdominal cavity. A 42-year-old otherwise healthy male presented with liver dysfunction at a general health checkup. Both HCV antibody and hepatitis B surface antigen were negative. Laboratory examination showed elevations in serum alpha-fetoprotein and PIVKA-II. Ultrasonography and computed tomography revealed multiple nodular lesions in the abdominal cavity with ascites without a possible primary tumor. Exploratory laparoscopy was performed, which revealed bloody ascites and multiple brown nodular tumors measuring approximately 10 mm in size that were disseminated on the perineum and mesentery. A postoperative PET-CT scan was performed but it did not reveal any evidence of a tumor in the liver. The tumors resected from the peritoneum were diagnosed as HCC. The present case of HCC was thought to have possibly developed from ectopic liver on the peritoneum or mesentery.

  2. Minimal surfaces, stratified multivarifolds, and the plateau problem

    CERN Document Server

    Thi, Dao Trong; Primrose, E J F; Silver, Ben

    1991-01-01

    Plateau's problem is a scientific trend in modern mathematics that unites several different problems connected with the study of minimal surfaces. In its simplest version, Plateau's problem is concerned with finding a surface of least area that spans a given fixed one-dimensional contour in three-dimensional space--perhaps the best-known example of such surfaces is provided by soap films. From the mathematical point of view, such films are described as solutions of a second-order partial differential equation, so their behavior is quite complicated and has still not been thoroughly studied. Soap films, or, more generally, interfaces between physical media in equilibrium, arise in many applied problems in chemistry, physics, and also in nature. In applications, one finds not only two-dimensional but also multidimensional minimal surfaces that span fixed closed "contours" in some multidimensional Riemannian space. An exact mathematical statement of the problem of finding a surface of least area or volume requir...

  3. Survival of mutations arising during invasions.

    Science.gov (United States)

    Miller, Judith R

    2010-03-01

    When a neutral mutation arises in an invading population, it quickly either dies out or 'surfs', i.e. it comes to occupy almost all the habitat available at its time of origin. Beneficial mutations can also surf, as can deleterious mutations over finite time spans. We develop descriptive statistical models that quantify the relationship between the probability that a mutation will surf and demographic parameters for a cellular automaton model of surfing. We also provide a simple analytic model that performs well at predicting the probability of surfing for neutral and beneficial mutations in one dimension. The results suggest that factors - possibly including even abiotic factors - that promote invasion success may also increase the probability of surfing and associated adaptive genetic change, conditioned on such success.

  4. [A case of carcinoma arising in a diverticulum of the transverse colon].

    Science.gov (United States)

    Nomi, Masako; Umemoto, Satoshi; Kikutake, Takashi; Hosaka, Seiji; Mase, Takahiro; Kawamoto, Shunji; Yoshida, Takahisa

    2014-11-01

    A 64 year-old woman presented with advanced, transverse colon cancer arising in the diverticulum. Tumor invasion extended beyond the serosa to the anal side of the colon. Anemia and fatigue progressed after 6 months of iron administration. The hemoglobin value was 5.3 g/dL and carcinoembryonic antigen (CEA) level was elevated to 44.2 ng/mL. A palpable and tender fist-sized mass was found in the right upper abdomen. Computed tomography (CT) revealed a low-density mass in the transverse colon invading beyond the serosa to the anal side of the colon. Right hemi-colectomy with lymph node dissection was performed. The resected specimen contained multiple diverticula including the one from which the tumor arose. Histological examination revealed a well-differentiated, tubular adenocarcinoma (UICC TNM T4bN0M0) arising in a transverse colon diverticulum. There has been no recurrence for 2 years. Colon cancer arising in a diverticulum may expand to the extra-serosa and easily invade to the adjacent organ. In such cases, malignancy should be considered.

  5. Addressing Cultural Diversity: Effects of a Problem-Based Intercultural Learning Unit

    Science.gov (United States)

    Busse, Vera; Krause, Ulrike-Marie

    2015-01-01

    This article explores to what extent a problem-based learning unit in combination with cooperative learning and affectively oriented teaching methods facilitates intercultural learning. As part of the study, students reflected on critical incidents, which display misunderstandings or conflicts that arise as a result of cultural differences. In…

  6. A perspective on problems and prospects for academic publishing in Geography

    NARCIS (Netherlands)

    Meadow, M.; Dietz, A.J.; Vandermotten, C.

    2016-01-01

    This commentary highlights problems of inequity in academic publishing in geography that arise from the increasing use of metrics as a measure of research quality. In so doing, we examine patterns in the ranking of geographical journals in the major global databases (e.g. Web of Science, Scopus) and

  7. Integrating routing decisions in public transportation problems

    CERN Document Server

    Schmidt, Marie E

    2014-01-01

    This book treats three planning problems arising in public railway transportation planning: line planning, timetabling, and delay management, with the objective to minimize passengers’ travel time. While many optimization approaches simplify these problems by assuming that passengers’ route choice is independent of the solution, this book focuses on models which take into account that passengers will adapt their travel route to the implemented planning solution. That is, a planning solution and passengers’ routes are determined and evaluated simultaneously. This work is technically deep, with insightful findings regarding complexity and algorithmic approaches to public transportation problems with integrated passenger routing. It is intended for researchers in the fields of mathematics, computer science, or operations research, working in the field of public transportation from an optimization standpoint. It is also ideal for students who want to gain intuition and experience in doing complexity proofs ...

  8. Refrigerators with chlorofluorohydrocarbon - always a problem. Why chlorofluorohydrocarbons are still an issue; Kuehlgeraete mit FCKW immer ein Problem. Warum Fluorchlorkohlenwasserstoffe noch ein Thema sind

    Energy Technology Data Exchange (ETDEWEB)

    Schnepel, Christiane

    2009-05-15

    The report discusses the following questions: What are CFCs and what is the environmental impact? Why is there still a CFCs problem in spite of the prohibition? Why is it so important to dispose old refrigerators in an appropriate way? What is the appropriate way for refrigerator disposal? What are the cost for refrigerator disposal and who is paying? What is the mass throughput balance and why is this value not suitable as control instrument? Which problems arise during disposal? What is the solution: where are we and what is the future?.

  9. The new framework for resolving the energy problem and its application to the utilization of nuclear technology

    International Nuclear Information System (INIS)

    Kurata, Kenji

    2002-01-01

    Until recently, the energy problem in Japan had been the problem of how enough energy could be supplied to various sectors in society under Japan's conditions of only a few energy resources existing within its territory. However, recently new environmental and social conditions are arising. These new conditions strongly affect not only concrete measures for solving the energy problem but also the characteristics of the energy problem itself. Nowadays, it seems to be impossible to resolve the energy problem without taking these conditions into consideration. For this reason, a new framework, which enables various social values to be reflected in concrete measures, is urgently needed to resolve the energy problem. This thesis uses the ISO14001 framework to consider a possible solution over the energy problem. In the first part of this thesis, an examination shows that the ISO14001 framework should be generalized beyond the original objective of dealing with environmental problems to accommodate any kind of problems caused by newly arising social values. This generalized framework is defined as a 'Social measure' and expected to enhance the resolution of the problem in socially appropriate manner. In the second part, this paper uses the idea of the Social measure to consider a possible solution to recover public trust on the utilization of nuclear technology, which is regarded as a typical energy problem under the social condition. (author)

  10. Chemical contaminants in the 81Rb→/sup 81m/Kr generator arising from target deterioration

    International Nuclear Information System (INIS)

    Finn, R.D.; Vora, M.; Boothe, T.; Kothari, P.; Emran, A.

    1985-01-01

    A cyclotron adjunct to a large medical center is an extremely useful tool in the armamentarium for basic biomedical research and clinical applications. However, specific quality assurances must be applied to diagnostic radionuclides that are routinely prepared. The lack of data on the toxicity of a variety of fabrication materials used for the preparation of an automated cyclotron processing system, such as the 81 Rb→/sup 81m/Kr generator system, should be of concern. Of paramount importance is the design of an efficient and reproducible system requiring minimal maintenance. The stability of various components toward their surroundings, resistance to radiation damage, and temperature considerations must be addressed. In spite of conscientious planning, problems arise when unanticipated chemical moieties formed either from electrolytic and/or radiolytic processes appear. The authors experience with these unexpected species, as well as a hypothetical explanation of their origin, are presented

  11. Radioactive wastes: present problems and future prospects

    International Nuclear Information System (INIS)

    Gauvenet, Andre

    1975-01-01

    The main characteristics of radioactive wastes are described and the present problems arising from liquid or gas effluents are considered. It is concluded that nuclear power stations are considerably less pollutant, at equal capacity, than conventional power stations. Programs of investigation are now being developed to meet with the foreseeable increase of activity. The problem is: first, to maintain absorbed doses at their present level and second, to study the problem of long-lived elements the storage of which would, in the long run create a nuisance on a world scale. The different waste storage techniques now in use are described and current investigations and works are exposed some of which, like vitrification, have already begun to be put into application. After having noted that the problem of wastes constitutes doubtless a difficulty in the technical field and, maybe even more so in the psychological field, the conditions are defined which will have to be met in order that this problem should not hinder the short- and long-term development of nuclear energy [fr

  12. Bricolage Programming and Problem Solving Ability in Young Children : an Exploratory Study

    OpenAIRE

    Rose, Simon

    2016-01-01

    Visual programming environments, such as Scratch, are increasingly being used by schools to teach problem solving and computational thinking skills. However, academic research is divided on the effect that visual programming has on problem solving in a computational context. This paper focuses on the role of bricolage programming in this debate; a bottom-up programming approach that arises when using block-style programming interfaces. Bricolage programming was a term originally used to descr...

  13. [Specific problems posed by carbohydrate utilization in the rainbow trout].

    Science.gov (United States)

    Bergot, F

    1979-01-01

    Carbohydrate incorporation in trout diets arises problems both at digestive and metabolic levels. Digestive utilization of carbohydrate closely depends on their molecular weight. In addition, in the case of complex carbohydrates (starches), different factors such as the level of incorporation, the amount consumed and the physical state of starch influence the digestibility. The measurement of digestibility in itself is confronted with methodological difficulties. The way the feces are collected can affect the digestion coefficient. Dietary carbohydrates actually serve as a source of energy. Nevertheless, above a certain level in the diet, intolerance phenomena may appear. The question that arises now is to establish the optimal part that carbohydrates can take in the metabolizable energy of a given diet.

  14. Coping with Problems of Understanding in Interorganizational Relationships: Using Formalization as a Means to make Sense

    NARCIS (Netherlands)

    P.W.L. Vlaar (Paul); F.A.J. van den Bosch (Frans)

    2006-01-01

    textabstractResearch into the management of interorganizational relationships has hitherto primarily focused on problems of coordination, control and to a lesser extent, legitimacy. In this article, we assert that partners cooperating in such relationships are also confronted with ‘problems of

  15. Mind over matter? I: philosophical aspects of the mind-brain problem.

    Science.gov (United States)

    Schimmel, P

    2001-08-01

    To conceptualize the essence of the mind-body or mind-brain problem as one of metaphysics rather than science, and to propose a formulation of the problem in the context of current scientific knowledge and its limitations. The background and conceptual parameters of the mind-body problem are delineated, and the limitations of brain research in formulating a solution identified. The problem is reformulated and stated in terms of two propositions. These constitute a 'double aspect theory'. The problem appears to arise as a consequence of the conceptual limitations of the human mind, and hence remains essentially a metaphysical one. A 'double aspect theory' recognizes the essential unity of mind and brain, while remaining consistent with the dualism inherent in human experience.

  16. Relative locality and the soccer ball problem

    International Nuclear Information System (INIS)

    Amelino-Camelia, Giovanni; Freidel, Laurent; Smolin, Lee; Kowalski-Glikman, Jerzy

    2011-01-01

    We consider the behavior of macroscopic bodies within the framework of relative locality [G. Amelino-Camelia, L. Freidel, J. Kowalski-Glikman, and L. Smolin, arXiv:1101.0931]. This is a recent proposal for Planck scale modifications of the relativistic dynamics of particles which are described as arising from deformations in the geometry of momentum space. We consider and resolve a common objection against such proposals, which is that, even if the corrections are small for elementary particles in current experiments, they are huge when applied to composite systems such as soccer balls, planets, and stars, with energies E macro much larger than M P . We show that this soccer ball problem does not arise within the framework of relative locality because the nonlinear effects for the dynamics of a composite system with N elementary particles appear at most of order E macro /N·M P .

  17. Functioning and Participation Problems of Students with ADHD in Higher Education: Which Reasonable Accommodations Are Effective?

    Science.gov (United States)

    Jansen, Dorien; Petry, Katja; Ceulemans, Eva; van der Oord, Saskia; Noens, Ilse; Baeyens, Dieter

    2017-01-01

    Students with ADHD struggle in higher education as a result of various functioning and participation problems. However, there are remaining gaps in the literature. First, it remains unclear how often and during which teaching and evaluation methods problems arise. Second, we do not yet know which reasonable accommodations are most effective to…

  18. The use of Adomian decomposition method for solving problems in calculus of variations

    Directory of Open Access Journals (Sweden)

    Mehdi Dehghan

    2006-01-01

    Full Text Available In this paper, a numerical method is presented for finding the solution of some variational problems. The main objective is to find the solution of an ordinary differential equation which arises from the variational problem. This work is done using Adomian decomposition method which is a powerful tool for solving large amount of problems. In this approach, the solution is found in the form of a convergent power series with easily computed components. To show the efficiency of the method, numerical results are presented.

  19. Squamous Cell Carcinoma Arising in Mature Teratoma of the Ovary Masquerading as Abdominal Tuberculosis

    Directory of Open Access Journals (Sweden)

    Shreeya Taresh Indulkar

    2018-01-01

    Full Text Available Pure squamous cell carcinoma (SCC of the ovary is rare. SCC can arise in a mature teratoma (MT, ovarian endometriosis or in a Brenner tumor. SCC is the most common malignant transformation arising in MT and comprises 80% of all cases. Such neoplastic transformations are extremely difficult either to predict or detect early. The mechanism of malignant transformation has not been completely understood. Due to the rarity and the aggressive course, diagnosis and treatment constitute a big challenge. We report a case of SCC arising in MT presenting with a huge abdominopelvic mass and abundant peritoneal collections clinically masquerading as abdominal tuberculosis. A review of literature with special emphasis on prognosis and treatment modalities is also presented.

  20. Some dynamic resource allocation problems in wireless networks

    Science.gov (United States)

    Berry, Randall

    2001-07-01

    We consider dynamic resource allocation problems that arise in wireless networking. Specifically transmission scheduling problems are studied in cases where a user can dynamically allocate communication resources such as transmission rate and power based on current channel knowledge as well as traffic variations. We assume that arriving data is stored in a transmission buffer, and investigate the trade-off between average transmission power and average buffer delay. A general characterization of this trade-off is given and the behavior of this trade-off in the regime of asymptotically large buffer delays is explored. An extension to a more general utility based quality of service definition is also discussed.

  1. THE MULTIPLE CHOICE PROBLEM WITH INTERACTIONS BETWEEN CRITERIA

    Directory of Open Access Journals (Sweden)

    Luiz Flavio Autran Monteiro Gomes

    2015-12-01

    Full Text Available ABSTRACT An important problem in Multi-Criteria Decision Analysis arises when one must select at least two alternatives at the same time. This can be denoted as a multiple choice problem. In other words, instead of evaluating each of the alternatives separately, they must be combined into groups of n alternatives, where n = 2. When the multiple choice problem must be solved under multiple criteria, the result is a multi-criteria, multiple choice problem. In this paper, it is shown through examples how this problemcan be tackled on a bipolar scale. The Choquet integral is used in this paper to take care of interactions between criteria. A numerical application example is conducted using data from SEBRAE-RJ, a non-profit private organization that has the mission of promoting competitiveness, sustainable developmentand entrepreneurship in the state of Rio de Janeiro, Brazil. The paper closes with suggestions for future research.

  2. Thermal-hydraulic methods in fast reactor safety

    International Nuclear Information System (INIS)

    Weber, D.P.; Briggs, L.L.

    1985-01-01

    Methods for the solution of thermal-hydraulic problems in liquid metal fast breeder reactors (LMFBRs) arising primarily from transient accident analysis are reviewed. Principal emphasis is given to the important phenomenological issues of sodium boiling and fuel motion. Descriptions of representative phenomenological and mathematical models, computational algorithms, advantages and limitations of the approaches, and current research needs and directions are provided

  3. Methods of using the quadratic assignment problem solution

    Directory of Open Access Journals (Sweden)

    Izabela Kudelska

    2012-09-01

    Full Text Available Background: Quadratic assignment problem (QAP is one of the most interesting of combinatorial optimization. Was presented by Koopman and Beckamanna in 1957, as a mathematical model of the location of indivisible tasks. This problem belongs to the class NP-hard issues. This forces the application to the solution already approximate methods for tasks with a small size (over 30. Even though it is much harder than other combinatorial optimization problems, it enjoys wide interest because it models the important class of decision problems. Material and methods: The discussion was an artificial intelligence tool that allowed to solve the problem QAP, among others are: genetic algorithms, Tabu Search, Branch and Bound. Results and conclusions: QAP did not arise directly as a model for certain actions, but he found its application in many areas. Examples of applications of the problem is: arrangement of buildings on the campus of the university, layout design of electronic components in systems with large scale integration (VLSI, design a hospital, arrangement of keys on the keyboard.

  4. Characterization of Rayleigh backscattering arising in various two-mode fibers

    NARCIS (Netherlands)

    Yu, Dawei; Fu, Songnian; Cao, Zizheng; Tang, Ming; Deng, Lei; Liu, Deming; Giles, I.; Koonen, T.; Okonkwo, C.

    2016-01-01

    We experimentally characterize the mode dependent characteristics of Rayleigh backscattering (RB) arising in various two-mode fibers (TMFs). With the help of an all-fiber photonic lantern, we are able to measure the RB power at individual modes. Consequently, mode dependent power distribution of RB

  5. Exercises and problems in mathematical methods of physics

    CERN Document Server

    Cicogna, Giampaolo

    2018-01-01

    This book presents exercises and problems in the mathematical methods of physics with the aim of offering undergraduate students an alternative way to explore and fully understand the mathematical notions on which modern physics is based. The exercises and problems are proposed not in a random order but rather in a sequence that maximizes their educational value. Each section and subsection starts with exercises based on first definitions, followed by groups of problems devoted to intermediate and, subsequently, more elaborate situations. Some of the problems are unavoidably "routine", but others bring to the forenontrivial properties that are often omitted or barely mentioned in textbooks. There are also problems where the reader is guided to obtain important results that are usually stated in textbooks without complete proofs. In all, some 350 solved problems covering all mathematical notions useful to physics are included. While the book is intended primarily for undergraduate students of physics, students...

  6. Contributions to thermal and fluid dynamic problems in nuclear technology

    International Nuclear Information System (INIS)

    Mueller, U.; Krebs, L.; Rust, K.

    1984-02-01

    The majority of contributions compiled in this report deals with thermal and fluid dynamic problems in nuclear engineering. Especially problems of heat transfer and cooling are represented which may arise during and afer a loss-of-coolant accident both in light water reactors and in liquid metal cooled fast breeder reactors. Papers on the mass transfer in pressurized water, tribological problems in sodium cooled reactors, the fluid dynamics of pulsed column, and fundamental investigations of convective flows supplement these contributions on problems connected with accidents. Furthermore, a keynote paper presents the individual activities relating to the reliability of reactor components, a field recently included in our research program. Technical solutions to special problems are closely connected to the investigations based on experiments. Therefore, several contributions deal with new developments in technology and measuring techniques. (orig.) [de

  7. Endometrial Stromal Sarcoma Arising in Colorectal Endometriosis: A Case Report and Review of the Literature

    Directory of Open Access Journals (Sweden)

    Qiao Wang

    2015-01-01

    Full Text Available Extrauterine endometrial stromal sarcoma (ESS arising in endometriosis is extremely rare, particularly in the colorectum. It should always be included in the differential diagnosis of primary tumors originating from gastrointestinal tract in females, given that preoperative endoscopical biopsy may reveal no specific changes. We reported a case of ESS arising in colorectal endometriosis and reviewed the previous 7 cases reported in the English literature. Our patient, who was unavailable for tumor resection and refused further adjuvant therapy, played a role in representing the natural history of low-grade extragenital ESS. This case was the only death from ESS arising in colorectal endometriosis.

  8. Chondrosarcoma arising within a radiation-induced osteochondroma several years following childhood total body irradiation: Case report

    Energy Technology Data Exchange (ETDEWEB)

    Nagata, Shuji [Kurume University Hospital, Department of Radiology, Fukuoka (Japan); Shen, Robert K. [Mayo Clinic, Department of Surgery, Rochester, MN (United States); Laack, Nadia N. [Mayo Clinic, Department of Radiation Oncology, Rochester, MN (United States); Inwards, Carrie Y. [Mayo Clinic, Department of Pathology, Rochester, MN (United States); Wenger, Doris E.; Amrami, Kimberly K. [Mayo Clinic, Department of Radiology, Rochester, MN (United States)

    2013-08-15

    Malignant degeneration arising in radiation-induced osteochondromas is extremely rare. We report a case of a 34-year-old man with a chondrosarcoma arising from an osteochondroma of the left posterior eighth rib that developed following total body irradiation received as part of the conditioning regimen prior to bone marrow transplantation at age 8. To our knowledge, this is only the fourth reported case of a chondrosarcoma arising within a radiation-induced osteochondroma and the first case occurring following childhood total body irradiation. (orig.)

  9. Chondrosarcoma arising within a radiation-induced osteochondroma several years following childhood total body irradiation: Case report

    International Nuclear Information System (INIS)

    Nagata, Shuji; Shen, Robert K.; Laack, Nadia N.; Inwards, Carrie Y.; Wenger, Doris E.; Amrami, Kimberly K.

    2013-01-01

    Malignant degeneration arising in radiation-induced osteochondromas is extremely rare. We report a case of a 34-year-old man with a chondrosarcoma arising from an osteochondroma of the left posterior eighth rib that developed following total body irradiation received as part of the conditioning regimen prior to bone marrow transplantation at age 8. To our knowledge, this is only the fourth reported case of a chondrosarcoma arising within a radiation-induced osteochondroma and the first case occurring following childhood total body irradiation. (orig.)

  10. AI tools in computer based problem solving

    Science.gov (United States)

    Beane, Arthur J.

    1988-01-01

    The use of computers to solve value oriented, deterministic, algorithmic problems, has evolved a structured life cycle model of the software process. The symbolic processing techniques used, primarily in research, for solving nondeterministic problems, and those for which an algorithmic solution is unknown, have evolved a different model, much less structured. Traditionally, the two approaches have been used completely independently. With the advent of low cost, high performance 32 bit workstations executing identical software with large minicomputers and mainframes, it became possible to begin to merge both models into a single extended model of computer problem solving. The implementation of such an extended model on a VAX family of micro/mini/mainframe systems is described. Examples in both development and deployment of applications involving a blending of AI and traditional techniques are given.

  11. Stability Estimates for h-p Spectral Element Methods for Elliptic Problems

    NARCIS (Netherlands)

    Dutt, Pravir; Tomar, S.K.; Kumar, B.V. Rathish

    2002-01-01

    In a series of papers of which this is the first we study how to solve elliptic problems on polygonal domains using spectral methods on parallel computers. To overcome the singularities that arise in a neighborhood of the corners we use a geometrical mesh. With this mesh we seek a solution which

  12. Analytic approximations to nonlinear boundary value problems modeling beam-type nano-electromechanical systems

    Energy Technology Data Exchange (ETDEWEB)

    Zou, Li [Dalian Univ. of Technology, Dalian City (China). State Key Lab. of Structural Analysis for Industrial Equipment; Liang, Songxin; Li, Yawei [Dalian Univ. of Technology, Dalian City (China). School of Mathematical Sciences; Jeffrey, David J. [Univ. of Western Ontario, London (Canada). Dept. of Applied Mathematics

    2017-06-01

    Nonlinear boundary value problems arise frequently in physical and mechanical sciences. An effective analytic approach with two parameters is first proposed for solving nonlinear boundary value problems. It is demonstrated that solutions given by the two-parameter method are more accurate than solutions given by the Adomian decomposition method (ADM). It is further demonstrated that solutions given by the ADM can also be recovered from the solutions given by the two-parameter method. The effectiveness of this method is demonstrated by solving some nonlinear boundary value problems modeling beam-type nano-electromechanical systems.

  13. Problems and issues for short-haul air transportation.

    Science.gov (United States)

    Vittek, J. F., Jr.

    1972-01-01

    The problems of developing an efficient short-haul air system are not primarily technical, but economic and political. The key issues are whether the community will accept new and expanded air facilities, what standards of service the passengers will demand and how the system will evolve. The solutions recommended are national in scope and require the federal government to take a leading role.

  14. A possible solution of the flavor problem and radiative neutrino masses

    International Nuclear Information System (INIS)

    Adulpravitchai, Adisorn

    2010-01-01

    In this thesis, we discuss two important problems of the Standard Model of Particle Physics (SM), namely the flavor problem and the reason for the smallness of neutrino masses. The first one might be related to the origin of non-abelian discrete flavor symmetries. We discuss the possibility of obtaining them from an underlying continuous flavor symmetry, i.e. SU(2) or SU(3) through spontaneous symmetry breaking. Moreover, we investigate their possible origin from an orbifold compactification. We discuss all non-abelian discrete symmetries, which can arise from an orbifold T 2 /Z N . They are A 4 , S 4 , D 4 , D 3 , and D 6 . We present the idea of combining the breaking of an orbifold GUT and the flavor symmetry arising from the orbifold. We demonstrate the construction in a 6d SUSY SO(10) x S 4 . For the second problem, we propose a one-loop neutrino mass model in the left-right symmetric framework. We observe the transmitted hierarchy from the charged lepton masses to the right-handed neutrino masses, which we call ''Radiative Transmission of Lepton Flavor Hierarchy''. Finally, we study the phenomenological aspects of the model such as lepton flavor violation (LFV), flavor number violation (FNV), and flavor changing neutral currents (FCNCs). (orig.)

  15. Visual integration dysfunction in schizophrenia arises by the first psychotic episode and worsens with illness duration.

    Science.gov (United States)

    Keane, Brian P; Paterno, Danielle; Kastner, Sabine; Silverstein, Steven M

    2016-05-01

    Visual integration dysfunction characterizes schizophrenia, but prior studies have not yet established whether the problem arises by the first psychotic episode or worsens with illness duration. To investigate the issue, we compared chronic schizophrenia patients (SZs), first episode psychosis patients (FEs), and well-matched healthy controls on a brief but sensitive psychophysical task in which subjects attempted to locate an integrated shape embedded in noise. Task difficulty depended on the number of noise elements co-presented with the shape. For half of the experiment, the entire display was scaled down in size to produce a high spatial frequency (HSF) condition, which has been shown to worsen patient integration deficits. Catch trials-in which the circular target appeared without noise-were also added so as to confirm that subjects were paying adequate attention. We found that controls integrated contours under noisier conditions than FEs, who, in turn, integrated better than SZs. These differences, which were at times large in magnitude (d = 1.7), clearly emerged only for HSF displays. Catch trial accuracy was above 95% for each group and could not explain the foregoing differences. Prolonged illness duration predicted poorer HSF integration across patients, but age had little effect on controls, indicating that the former factor was driving the effect in patients. Taken together, a brief psychophysical task efficiently demonstrates large visual integration impairments in schizophrenia. The deficit arises by the first psychotic episode, worsens with illness duration, and may serve as a biomarker of illness progression. (PsycINFO Database Record (c) 2016 APA, all rights reserved).

  16. How Do They Solve It? An Insight into the Learner's Approach to the Mechanism of Physics Problem Solving

    Science.gov (United States)

    Hegde, Balasubrahmanya; Meera, B. N.

    2012-01-01

    A perceived difficulty is associated with physics problem solving from a learner's viewpoint, arising out of a multitude of reasons. In this paper, we have examined the microstructure of students' thought processes during physics problem solving by combining the analysis of responses to multiple-choice questions and semistructured student…

  17. Multi-focal lobular carcinoma in situ arising in benign phylodes tumor: A case report

    International Nuclear Information System (INIS)

    Lee, Taeg Ki; Choi, Chang Hwan; Kim, Youn Jeong; Kim, Mi Young; Lee, Kyung Hee; Cho, Soon Gu

    2015-01-01

    Coexistent breast malignancy arising in phyllodes tumor is extremely rare, and most of them are incidental reports after surgical excision. Coexistent malignancy in phyllodes tumor can vary from in-situ to invasive carcinoma. Lobular neoplasia is separated into atypical lobular hyperplasia and lobular carcinoma in situ (LCIS). LCIS is known to have a higher risk of developing invasive cancer. We reported imaging findings of multifocal LCIS arising in benign phyllodes tumor

  18. Multi-focal lobular carcinoma in situ arising in benign phylodes tumor: A case report

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Taeg Ki; Choi, Chang Hwan; Kim, Youn Jeong; Kim, Mi Young; Lee, Kyung Hee; Cho, Soon Gu [Inha University Hospital, Incheon (Korea, Republic of)

    2015-08-15

    Coexistent breast malignancy arising in phyllodes tumor is extremely rare, and most of them are incidental reports after surgical excision. Coexistent malignancy in phyllodes tumor can vary from in-situ to invasive carcinoma. Lobular neoplasia is separated into atypical lobular hyperplasia and lobular carcinoma in situ (LCIS). LCIS is known to have a higher risk of developing invasive cancer. We reported imaging findings of multifocal LCIS arising in benign phyllodes tumor.

  19. About the Big Graphs Arising when Forming the Diagnostic Models in a Reconfigurable Computing Field of Functional Monitoring and Diagnostics System of the Spacecraft Onboard Control Complex

    Directory of Open Access Journals (Sweden)

    L. V. Savkin

    2015-01-01

    Full Text Available One of the problems in implementation of the multipurpose complete systems based on the reconfigurable computing fields (RCF is the problem of optimum redistribution of logicalarithmetic resources in growing scope of functional tasks. Irrespective of complexity, all of them are transformed into an orgraph, which functional and topological structure is appropriately imposed on the RCF based, as a rule, on the field programmable gate array (FPGA.Due to limitation of the hardware configurations and functions realized by means of the switched logical blocks (SLB, the abovementioned problem becomes even more critical when there is a need, within the strictly allocated RCF fragment, to realize even more complex challenge in comparison with the problem which was solved during the previous computing step. In such cases it is possible to speak about graphs of big dimensions with respect to allocated RCF fragment.The article considers this problem through development of diagnostic algorithms to implement diagnostics and control of an onboard control complex of the spacecraft using RCF. It gives examples of big graphs arising with respect to allocated RCF fragment when forming the hardware levels of a diagnostic model, which, in this case, is any hardware-based algorithm of diagnostics in RCF.The article reviews examples of arising big graphs when forming the complicated diagnostic models due to drastic difference in formation of hardware levels on closely located RCF fragments. It also pays attention to big graphs emerging when the multichannel diagnostic models are formed.Three main ways to solve the problem of big graphs with respect to allocated RCF fragment are given. These are: splitting the graph into fragments, use of pop-up windows with relocating and memorizing intermediate values of functions of high hardware levels of diagnostic models, and deep adaptive update of diagnostic model.It is shown that the last of three ways is the most efficient

  20. Radiation-induced squamous carcinoma arising within a seborrhoeic keratosis

    Energy Technology Data Exchange (ETDEWEB)

    Suvarna, S.K.; Bagary, M.; Glazer, G. (Saint Mary' s Hospital, London (United Kingdom))

    1993-04-01

    Seborrhoeic keratoses (SK) are common skin tumours. They are benign, and present little difficulty in management. However, rare malignant transformation is recognized. The authors report a case of a squamous cell carcinoma arising from dysplastic changes within a long-standing SK on the chest wall of a 75-year-old retired radiologist, and consider the role of radiation in inducing malignant change within SKs. (author).

  1. Radiation-induced squamous carcinoma arising within a seborrhoeic keratosis

    International Nuclear Information System (INIS)

    Suvarna, S.K.; Bagary, M.; Glazer, G.

    1993-01-01

    Seborrhoeic keratoses (SK) are common skin tumours. They are benign, and present little difficulty in management. However, rare malignant transformation is recognized. The authors report a case of a squamous cell carcinoma arising from dysplastic changes within a long-standing SK on the chest wall of a 75-year-old retired radiologist, and consider the role of radiation in inducing malignant change within SKs. (author)

  2. Women's Healthcare, Censorship, and the Library: Problems, Issues, Questions.

    Science.gov (United States)

    Kuhl, Nancy

    The goal of this paper is to explore a number of examples of the censorship of women's healthcare issues and to investigate issues and questions related to those examples. The paper looks primarily at censorship in the United States; however, the problems and issues discussed are international in scope, and some international examples are…

  3. Mucinous adenocarcinoma arising at the anastomotic site after operation for hirschsprung's disease: case report

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Hyung Soo; Yoon, Kwon Ha [College of Medicine, Wonkwang Univ., Iksan (Korea, Republic of)

    2004-02-01

    To our knowledge, rectal cancer arising at the anastomotic site after surgery for Hirschsprung's disease has not been reported. We report a case of mucinous adenocarcinoma arising at the anastomotic site after Soave operation 26 years ago.

  4. On a Mixed Nonlinear One Point Boundary Value Problem for an Integrodifferential Equation

    Directory of Open Access Journals (Sweden)

    Mesloub Said

    2008-01-01

    Full Text Available This paper is devoted to the study of a mixed problem for a nonlinear parabolic integro-differential equation which mainly arise from a one dimensional quasistatic contact problem. We prove the existence and uniqueness of solutions in a weighted Sobolev space. Proofs are based on some a priori estimates and on the Schauder fixed point theorem. we also give a result which helps to establish the regularity of a solution.

  5. Incentive Problems in Banking Supervision: The European Case

    OpenAIRE

    Schüler, Martin

    2003-01-01

    This paper discusses the incentive conflicts that arise in banking supervision in the EU in a principal-agent framework, where the regulator is the agent and the taxpayers is the principal. The regulatory agent in addition to maintaining financial stability (the objective of the principal) may pursue private interests. Incomplete information, insufficient accountability of the agent and lack of enforceability of compliance result in an incentive problem. A reform of the European supervisory s...

  6. Computerized systems of NPP operators support. (Psychological problems)

    International Nuclear Information System (INIS)

    Mashin, V.A.

    1995-01-01

    Operator psychological problems arising in the work with NPP operators support computerized systems (OSCS) are considered. The conclusion is made that the OSCS intellectual application will bring the operator into dangerous dependence on his computerized assistant. To avoid this danger it is necessary by creation of the OSCS to divide specially the tasks areas of the operator and OSCS in order to assure the active role of the operator in the NPP control

  7. Solving network design problems via decomposition, aggregation and approximation

    CERN Document Server

    Bärmann, Andreas

    2016-01-01

    Andreas Bärmann develops novel approaches for the solution of network design problems as they arise in various contexts of applied optimization. At the example of an optimal expansion of the German railway network until 2030, the author derives a tailor-made decomposition technique for multi-period network design problems. Next, he develops a general framework for the solution of network design problems via aggregation of the underlying graph structure. This approach is shown to save much computation time as compared to standard techniques. Finally, the author devises a modelling framework for the approximation of the robust counterpart under ellipsoidal uncertainty, an often-studied case in the literature. Each of these three approaches opens up a fascinating branch of research which promises a better theoretical understanding of the problem and an increasing range of solvable application settings at the same time. Contents Decomposition for Multi-Period Network Design Solving Network Design Problems via Ag...

  8. Toward an Improved Representation of Middle Atmospheric Dynamics Thanks to the ARISE Project

    Czech Academy of Sciences Publication Activity Database

    Blanc, E.; Ceranna, L.; Hauchecorne, A.; Charlton-Perez, A.; Marchetti, E.; Evers, L.G.; Kvaerna, T.; Laštovička, Jan; Eliasson, L.; Crosby, N. B.; Blanc-Benon, P.; Le Pichon, A.; Brachet, N.; Pilger, C.; Keckhut, P.; Assink, J.D.; Smets, P. S. M.; Lee, C. F.; Kero, J.; Šindelářová, Tereza; Kämpfer, N.; Rüfenacht, R.; Farges, T.; Millet, C.; Näsholm, S. P.; Gibbons, S. J.; Espy, P. J.; Hibbins, R. E.; Heinrich, P.; Ripepe, M.; Khaykin, S.; Mze, N.; Chum, Jaroslav

    2018-01-01

    Roč. 39, č. 2 (2018), s. 171-225 ISSN 0169-3298 EU Projects: European Commission(XE) 284387 - ARISE; European Commission(XE) 653980 - ARISE2 Institutional support: RVO:68378289 Keywords : Atmospheric dynamics * Middle atmosphere * Infrasound * Gravity waves * Volcanoes * Atmospheric disturbances * Extreme events * stratospheric temperature trends * total solar eclipse * wave momentum flux * natural infrasound * acoustic-waves * polar-low * model simulations * sudden warmings * Doppler lidar Subject RIV: DG - Athmosphere Sciences, Meteorology OBOR OECD: Meteorology and atmospheric sciences Impact factor: 4.413, year: 2016 https://link.springer.com/article/10.1007/s10712-017-9444-0

  9. Adenocarcinoma arising in female urethral diverticulum

    International Nuclear Information System (INIS)

    Patanaphan, V.; Prempree, T.; Sewchand, W.; Hafiz, M.A.; Jaiwatana, J.

    1983-01-01

    Cancer arising from a female urethral diverticulum is rare, and because of its rarity, a review of the medical literature reveals significant nonuniformity in its management. We report an additional 2 cases of this disease, one of which has an even rarer feature of being mucin-producing. The management of our 2 cases is presented in detail and in line with the management of female urethral cancer. From our extensive literature search, diverticulectomy alone showed poor results with the highest rate of recurrence (67%). Extensive surgery, either in the form of cystourethrectomy or anterior exenteration, offered results comparable with those of combined therapy (diverticulectomy and full course of irradiation for early cases; preoperative irradiation followed by cystourethrectomy for late cases). Individualization of radiation treatment and cooperative effort between urologist and radiation oncologist are essential if best results are to be achieved

  10. Primary diffuse large B cell lymphoma arising from a leiomyoma of the uterine corpus.

    Science.gov (United States)

    Zhao, Lianhua; Ma, Qiang; Wang, Qiushi; Zeng, Ying; Luo, Qingya; Xiao, Hualiang

    2016-01-20

    Primary diffuse large B cell lymphoma (DLBCL) of the uterus is rare, and primary DLBCL arising from a uterine leiomyoma (collision tumor) has not been reported in the literature. We describe the clinical, histological, immunohistochemical, and molecular features of primary DLBCL arising from a leiomyoma in the uterine corpus. A 73-year-old female patient had a uterine mass for 23 years. An ultrasound scan revealed marked enlargement of the uterus, measuring 18.2 × 13 × 16.3 cm, with a 17.6 × 10.9 × 11.6 cm hypoechoic mass in the uterine corpus. The tumors consisted of medium- to large-sized cells exhibiting a diffuse pattern of growth with a well-circumscribed leiomyoma. The neoplastic cells strongly expressed CD79α, CD20 and PAX5. Molecular analyses indicated clonal B-cell receptor gene rearrangement. To the best of our knowledge, no previous cases of primary DLBCL arising from a leiomyoma have been reported. It is necessary to differentiate a diagnosis of primary DLBCL arising from a leiomyoma from that of leiomyoma with florid reactive lymphocytic infiltration (lymphoma-like lesion). Careful analysis of clinical, histological, immunophenotypic, and genetic features is required to establish the correct diagnosis.

  11. Healthy younger and older adults control foot placement to avoid small obstacles during gait primarily by modulating step width

    Directory of Open Access Journals (Sweden)

    Schulz Brian W

    2012-10-01

    Full Text Available Abstract Background Falls are a significant problem in the older population. Most falls occur during gait, which is primarily regulated by foot placement. Variability of foot placement has been associated with falls, but these associations are inconsistent and generally for smooth, level flooring. This study investigates the control of foot placement and the associated gait variability in younger and older men and women (N=7/group, total N=28 while walking at three different speeds (slow, preferred, and fast across a control surface with no obstacles and surfaces with multiple (64 small (10cm long ×13mm high visible and hidden obstacles. Results Minimum obstacle distance between the shoe and nearest obstacle during each footfall was greater on the visible obstacles surface for older subjects because some of them chose to actively avoid obstacles. This obstacle avoidance strategy was implemented primarily by modulating step width and to a lesser extent step length as indicated by linear regressions of step width and length variability on minimum obstacle distance. Mean gait speed, step length, step width, and step time did not significantly differ by subject group, flooring surface, or obstacle avoidance strategy. Conclusions Some healthy older subjects choose to actively avoid small obstacles that do not substantially perturb their gait by modulating step width and, to a lesser extent, step length. It is not clear if this obstacle avoidance strategy is appropriate and beneficial or overcautious and maladaptive, as it results in fewer obstacles encountered at a consequence of a less efficient gait pattern that has been shown to indicate increased fall risk. Further research is needed on the appropriateness of strategy selection when the environmental demands and/or task requirements have multiple possible completion strategies with conflicting objectives (i.e. perceived safety vs. efficiency.

  12. Sumudu transform series expansion method for solving the local fractional Laplace equation in fractal thermal problems

    Directory of Open Access Journals (Sweden)

    Guo Zheng-Hong

    2016-01-01

    Full Text Available In this article, the Sumudu transform series expansion method is used to handle the local fractional Laplace equation arising in the steady fractal heat-transfer problem via local fractional calculus.

  13. Inverse scattering problems with multi-frequencies

    International Nuclear Information System (INIS)

    Bao, Gang; Li, Peijun; Lin, Junshan; Triki, Faouzi

    2015-01-01

    This paper is concerned with computational approaches and mathematical analysis for solving inverse scattering problems in the frequency domain. The problems arise in a diverse set of scientific areas with significant industrial, medical, and military applications. In addition to nonlinearity, there are two common difficulties associated with the inverse problems: ill-posedness and limited resolution (diffraction limit). Due to the diffraction limit, for a given frequency, only a low spatial frequency part of the desired parameter can be observed from measurements in the far field. The main idea developed here is that if the reconstruction is restricted to only the observable part, then the inversion will become stable. The challenging task is how to design stable numerical methods for solving these inverse scattering problems inspired by the diffraction limit. Recently, novel recursive linearization based algorithms have been presented in an attempt to answer the above question. These methods require multi-frequency scattering data and proceed via a continuation procedure with respect to the frequency from low to high. The objective of this paper is to give a brief review of these methods, their error estimates, and the related mathematical analysis. More attention is paid to the inverse medium and inverse source problems. Numerical experiments are included to illustrate the effectiveness of these methods. (topical review)

  14. The Topical Problems of Reengineering of Production Enterprises

    Directory of Open Access Journals (Sweden)

    Chumak Larysa F.

    2018-01-01

    Full Text Available The article is aimed at researching the problems of reengineering of industrial enterprises and determining the efficient ways of their solution. The essence of process of reengineering, conditions and expediency of carrying out reengineering were researched. Elements of the system of principles of reengineering, its stages, problems of implementation, and typical errors arising during reengineering, have been defined. It has been determined that reengineering should be closely connected with the strategies of industrial enterprise in order to achieve maximum efficiency of the enterprise’s activity and to prevent additional costs. Reengineering of an industrial enterprise should be supported by an appropriate organizational structure, sound information technology, and contemporary strategic considerations.

  15. Testicular artery arising from an aberrant right renal artery | Suluba ...

    African Journals Online (AJOL)

    This case report we discovered the rare variation of the origin of the right testicular artery arising from the right aberrant renal artery with double renal artery irrigating both left and right kidneys. These variations in the testicular arteries and renal arteries have implication to surgical procedures such as orchidopexy repair for ...

  16. College drinking behaviors: mediational links between parenting styles, parental bonds, depression, and alcohol problems.

    Science.gov (United States)

    Patock-Peckham, Julie A; Morgan-Lopez, Antonio A

    2007-09-01

    Mediational links between parenting styles (authoritative, authoritarian, permissive), parental bond (positive, negative), depression, alcohol use and abuse were tested. A 2-group, multiple-indicator, multiple-cause structural equation model with 441 (216 female, 225 male) college students was examined. In general, a poor parental bond with one's father was highly predictive of depression, a well-known predictor of alcohol abuse and related problems for both genders. In contrast, a positive parental bond with one's father significantly mediated the positive effects of authoritative fathering on depression, which then decreased alcohol use problems for both genders. For women, a negative parental bond with one's father significantly mediated the effect of having an authoritarian father on depression, which increased alcohol use problems. These findings suggest that parental influences on pathways to alcohol abuse through depression (primarily through fathers for both genders) are distinct from pathways stemming from poor impulse control (with influences primarily from the same-sex parents for both genders).

  17. Phase Transitions in Planning Problems: Design and Analysis of Parameterized Families of Hard Planning Problems

    Science.gov (United States)

    Hen, Itay; Rieffel, Eleanor G.; Do, Minh; Venturelli, Davide

    2014-01-01

    There are two common ways to evaluate algorithms: performance on benchmark problems derived from real applications and analysis of performance on parametrized families of problems. The two approaches complement each other, each having its advantages and disadvantages. The planning community has concentrated on the first approach, with few ways of generating parametrized families of hard problems known prior to this work. Our group's main interest is in comparing approaches to solving planning problems using a novel type of computational device - a quantum annealer - to existing state-of-the-art planning algorithms. Because only small-scale quantum annealers are available, we must compare on small problem sizes. Small problems are primarily useful for comparison only if they are instances of parametrized families of problems for which scaling analysis can be done. In this technical report, we discuss our approach to the generation of hard planning problems from classes of well-studied NP-complete problems that map naturally to planning problems or to aspects of planning problems that many practical planning problems share. These problem classes exhibit a phase transition between easy-to-solve and easy-to-show-unsolvable planning problems. The parametrized families of hard planning problems lie at the phase transition. The exponential scaling of hardness with problem size is apparent in these families even at very small problem sizes, thus enabling us to characterize even very small problems as hard. The families we developed will prove generally useful to the planning community in analyzing the performance of planning algorithms, providing a complementary approach to existing evaluation methods. We illustrate the hardness of these problems and their scaling with results on four state-of-the-art planners, observing significant differences between these planners on these problem families. Finally, we describe two general, and quite different, mappings of planning

  18. To the problem of foreign experience application for power generation management

    International Nuclear Information System (INIS)

    Barinov, V.A.

    1993-01-01

    The structure and organization of the United Power System in the former USSR and problems arised later in connection with its reorganization are discussed. It is shown that the model, in which the Russian power system operation efficiency is achieved via the mechanism of coordination and competition, but not via the marketing force actions, is the most advantageous one

  19. Competitive Benchmarking: An IS Research Approach to Address Wicked Problems with Big Data and Analytics

    NARCIS (Netherlands)

    W. Ketter (Wolfgang); M. Peters (Markus); J. Collins (John); A. Gupta (Alok)

    2015-01-01

    textabstractWicked problems like sustainable energy and financial market stability are societal challenges that arise from complex socio-technical systems in which numerous social, economic, political, and technical factors interact. Understanding and mitigating them requires research methods that

  20. Constraint-Based Local Search for Constrained Optimum Paths Problems

    Science.gov (United States)

    Pham, Quang Dung; Deville, Yves; van Hentenryck, Pascal

    Constrained Optimum Path (COP) problems arise in many real-life applications and are ubiquitous in communication networks. They have been traditionally approached by dedicated algorithms, which are often hard to extend with side constraints and to apply widely. This paper proposes a constraint-based local search (CBLS) framework for COP applications, bringing the compositionality, reuse, and extensibility at the core of CBLS and CP systems. The modeling contribution is the ability to express compositional models for various COP applications at a high level of abstraction, while cleanly separating the model and the search procedure. The main technical contribution is a connected neighborhood based on rooted spanning trees to find high-quality solutions to COP problems. The framework, implemented in COMET, is applied to Resource Constrained Shortest Path (RCSP) problems (with and without side constraints) and to the edge-disjoint paths problem (EDP). Computational results show the potential significance of the approach.

  1. Primary intraosseous carcinoma arising from odontogenic keratocyst with parotid lymph node metastasis. A case report

    Directory of Open Access Journals (Sweden)

    Siddesh Shenoy

    2007-01-01

    Full Text Available Squamous cell carcinoma (SCC arising from odontogenic cyst lining is rare. The exact incidence of carcinoma arising in odontogenic cyst is unknown, but it is estimated to vary between 1 and 2/1000. The pathogenesis is unknown, but a long-standing inflammation and continuous intracystic pressure have been suggested as possible causative factors. Metastasis from these lesions is not common (< 20%, and most of the carcinomas are moderately to well differentiated. To qualify as a primary intraosseous carcinoma, there must be no initial connection with the oral mucosa, overlying skin, or antral or nasal mucosa. This paper presents a case of primary intraosseous carcinoma arising from odontogenic keratocyst in the anterior mandible with metastasis to left parotid lymph nodes.

  2. Perfecting of shielding calculation technique against the gamma rays arising from a Tokamak with the TFR experience. Application to the conceptual design Tokamak TORE 2 SUPRA

    International Nuclear Information System (INIS)

    Diop, Cheikh M'Backe.

    1980-09-01

    The conception of the necessary shielding around a conceptual design Tokamak requires to execute an estimated calculation of the doses due to the different radiation sources arising from the machine: the thermonuclear neutron source and the gamma ray source emitted during the interaction of the runaway electrons with the diaphragm. In this study, we propose a theorical method to calculate this gamma source. We tackle also the shielding problem of the conceptual design Tokamak: TORE 2 SUPRA [fr

  3. Ethnic Problems in Sociological Work in Market Conditions

    OpenAIRE

    N E Aimautova; Leniungo ZhB Onzimba; O A Trykina

    2013-01-01

    The article considers some problems arising when a sociologist renders services to the customer; a general description of a modern sociologist's activities is given where their results can be seen as “goods”. The work of a sociologist fulfilled to order, is seen as something providing for managerial activities. At the same time, the sociologist taking the order either defines his individual position, or he does not. There may exist different limitations for the sociologist's self-identificati...

  4. Microbial diversity arising from thermodynamic constraints

    Science.gov (United States)

    Großkopf, Tobias; Soyer, Orkun S

    2016-01-01

    The microbial world displays an immense taxonomic diversity. This diversity is manifested also in a multitude of metabolic pathways that can utilise different substrates and produce different products. Here, we propose that these observations directly link to thermodynamic constraints that inherently arise from the metabolic basis of microbial growth. We show that thermodynamic constraints can enable coexistence of microbes that utilise the same substrate but produce different end products. We find that this thermodynamics-driven emergence of diversity is most relevant for metabolic conversions with low free energy as seen for example under anaerobic conditions, where population dynamics is governed by thermodynamic effects rather than kinetic factors such as substrate uptake rates. These findings provide a general understanding of the microbial diversity based on the first principles of thermodynamics. As such they provide a thermodynamics-based framework for explaining the observed microbial diversity in different natural and synthetic environments. PMID:27035705

  5. Microbial diversity arising from thermodynamic constraints.

    Science.gov (United States)

    Großkopf, Tobias; Soyer, Orkun S

    2016-11-01

    The microbial world displays an immense taxonomic diversity. This diversity is manifested also in a multitude of metabolic pathways that can utilise different substrates and produce different products. Here, we propose that these observations directly link to thermodynamic constraints that inherently arise from the metabolic basis of microbial growth. We show that thermodynamic constraints can enable coexistence of microbes that utilise the same substrate but produce different end products. We find that this thermodynamics-driven emergence of diversity is most relevant for metabolic conversions with low free energy as seen for example under anaerobic conditions, where population dynamics is governed by thermodynamic effects rather than kinetic factors such as substrate uptake rates. These findings provide a general understanding of the microbial diversity based on the first principles of thermodynamics. As such they provide a thermodynamics-based framework for explaining the observed microbial diversity in different natural and synthetic environments.

  6. Inverse problems with Poisson data: statistical regularization theory, applications and algorithms

    International Nuclear Information System (INIS)

    Hohage, Thorsten; Werner, Frank

    2016-01-01

    Inverse problems with Poisson data arise in many photonic imaging modalities in medicine, engineering and astronomy. The design of regularization methods and estimators for such problems has been studied intensively over the last two decades. In this review we give an overview of statistical regularization theory for such problems, the most important applications, and the most widely used algorithms. The focus is on variational regularization methods in the form of penalized maximum likelihood estimators, which can be analyzed in a general setup. Complementing a number of recent convergence rate results we will establish consistency results. Moreover, we discuss estimators based on a wavelet-vaguelette decomposition of the (necessarily linear) forward operator. As most prominent applications we briefly introduce Positron emission tomography, inverse problems in fluorescence microscopy, and phase retrieval problems. The computation of a penalized maximum likelihood estimator involves the solution of a (typically convex) minimization problem. We also review several efficient algorithms which have been proposed for such problems over the last five years. (topical review)

  7. Adenocarcinoma arising in rectal duplication cyst: case report and review of the literature.

    Science.gov (United States)

    Shivnani, Anand T; Small, William; Benson, Al; Rao, Sambasiva; Talamonti, Mark S

    2004-11-01

    Duplication cyst of the gastrointestinal (GI) tract is a rare congenital anomaly, and rectal duplication cysts comprise a small fraction these cases. Most patients present for the first time in adulthood, and the origin of rectal duplication cysts is unclear. Prior series document malignant transformation in approximately 20 per cent of cases. The following case report describes a carcinoma arising in a rectal duplication cyst. Given the lack of data demonstrating adequate control for patients with adenocarcinoma arising in a rectal duplication cyst and our experience with this patient, we recommend all patients undergo multidisciplinary evaluation prior to any therapy.

  8. Inverse problems in systems biology

    International Nuclear Information System (INIS)

    Engl, Heinz W; Lu, James; Müller, Stefan; Flamm, Christoph; Schuster, Peter; Kügler, Philipp

    2009-01-01

    Systems biology is a new discipline built upon the premise that an understanding of how cells and organisms carry out their functions cannot be gained by looking at cellular components in isolation. Instead, consideration of the interplay between the parts of systems is indispensable for analyzing, modeling, and predicting systems' behavior. Studying biological processes under this premise, systems biology combines experimental techniques and computational methods in order to construct predictive models. Both in building and utilizing models of biological systems, inverse problems arise at several occasions, for example, (i) when experimental time series and steady state data are used to construct biochemical reaction networks, (ii) when model parameters are identified that capture underlying mechanisms or (iii) when desired qualitative behavior such as bistability or limit cycle oscillations is engineered by proper choices of parameter combinations. In this paper we review principles of the modeling process in systems biology and illustrate the ill-posedness and regularization of parameter identification problems in that context. Furthermore, we discuss the methodology of qualitative inverse problems and demonstrate how sparsity enforcing regularization allows the determination of key reaction mechanisms underlying the qualitative behavior. (topical review)

  9. Contract Design: The problem of information asymmetry

    Directory of Open Access Journals (Sweden)

    Axel C. Mühlbacher

    2018-01-01

    Full Text Available Introduction: Integrated care systems are advocated as an effective method of improving the performance of healthcare systems. These systems outline a payment and care delivery model that intends to tie provider reimbursements to predefined quality metrics. Little is known about the contractual design and the main challenges of delegating “accountability” to these new kinds of organisations and/or contracts. The research question in this article focuses on how healthcare contracts can look like and which possible problems arise in designing such contracts. In this a special interest is placed on information asymmetries.  Methods: A comprehensive literature review on methods of designing contracts in Integrated Care was conducted. This article is the first in a row of three that all contribute to a specific issue in designing healthcare contracts. Starting with the organisation of contracts and information asymmetries, part 2 focusses on financial options and risks and part 3 finally concludes with the question of risk management and evaluation.  Results: Healthcare contracting between providers and payers will have a major impact on the overall design of future healthcare systems. If Integrated care systems or any other similar concept of care delivery are to be contracted directly by payers to manage the continuum of care the costs of market utilisation play an essential role. Transaction costs also arise in the course of the negotiation and implementation of contracts. These costs are the reason why it is generally not possible to conclude perfect (complete contracts. Problems with asymmetric distribution of information can relate to the situation before a contract is concluded (adverse selection and after conclusion of a contract (moral hazard.  Discussion and Conclusions: Information asymmetries are seen as a major obstacle to the efficient operation of integrated care programmes. Coordination and motivation problems cannot be solved

  10. Contract Design: The problem of information asymmetry.

    Science.gov (United States)

    Mühlbacher, Axel C; Amelung, Volker E; Juhnke, Christin

    2018-01-12

    Integrated care systems are advocated as an effective method of improving the performance of healthcare systems. These systems outline a payment and care delivery model that intends to tie provider reimbursements to predefined quality metrics. Little is known about the contractual design and the main challenges of delegating "accountability" to these new kinds of organisations and/or contracts. The research question in this article focuses on how healthcare contracts can look like and which possible problems arise in designing such contracts. In this a special interest is placed on information asymmetries. A comprehensive literature review on methods of designing contracts in Integrated Care was conducted. This article is the first in a row of three that all contribute to a specific issue in designing healthcare contracts. Starting with the organisation of contracts and information asymmetries, part 2 focusses on financial options and risks and part 3 finally concludes with the question of risk management and evaluation. Healthcare contracting between providers and payers will have a major impact on the overall design of future healthcare systems. If Integrated care systems or any other similar concept of care delivery are to be contracted directly by payers to manage the continuum of care the costs of market utilisation play an essential role. Transaction costs also arise in the course of the negotiation and implementation of contracts. These costs are the reason why it is generally not possible to conclude perfect (complete) contracts. Problems with asymmetric distribution of information can relate to the situation before a contract is concluded (adverse selection) and after conclusion of a contract (moral hazard). Information asymmetries are seen as a major obstacle to the efficient operation of integrated care programmes. Coordination and motivation problems cannot be solved at no-costs. The presented problems in the design of selective individual contracts

  11. Sequential Inverse Problems Bayesian Principles and the Logistic Map Example

    Science.gov (United States)

    Duan, Lian; Farmer, Chris L.; Moroz, Irene M.

    2010-09-01

    Bayesian statistics provides a general framework for solving inverse problems, but is not without interpretation and implementation problems. This paper discusses difficulties arising from the fact that forward models are always in error to some extent. Using a simple example based on the one-dimensional logistic map, we argue that, when implementation problems are minimal, the Bayesian framework is quite adequate. In this paper the Bayesian Filter is shown to be able to recover excellent state estimates in the perfect model scenario (PMS) and to distinguish the PMS from the imperfect model scenario (IMS). Through a quantitative comparison of the way in which the observations are assimilated in both the PMS and the IMS scenarios, we suggest that one can, sometimes, measure the degree of imperfection.

  12. 49 CFR 37.195 - Purchase or lease of OTRBs by private entities not primarily in the business of transporting people.

    Science.gov (United States)

    2010-10-01

    ... primarily in the business of transporting people. 37.195 Section 37.195 Transportation Office of the... transporting people. This section applies to all purchases or leases of new vehicles by private entities which are not primarily engaged in the business of transporting people, with respect to buses delivered to...

  13. A comment on the infra-red problem in the AdS/CFT correspondence

    International Nuclear Information System (INIS)

    Gottschalk, Hanno; Thaler, Horst

    2008-01-01

    In this note we report on some recent progress in proving the AdS/CFT correspondence for quantum fields using rigorously defined Euclidean path integrals. We also comment on the infra-red problem in the AdS/CFT correspondence and argue that it is different from the usual IR problem in constructive quantum field theory. To illustrate this, a triviality proof based on hypercontractivity estimates is given for the case of an ultraviolet regularized potential of type: φ 4 :. We also give a brief discussion on possible renormalization strategies and the specific problems that arise in this context. (orig.)

  14. A comment on the infra-red problem in the AdS/CFT correspondence

    Energy Technology Data Exchange (ETDEWEB)

    Gottschalk, Hanno; Thaler, Horst

    2008-03-15

    In this note we report on some recent progress in proving the AdS/CFT correspondence for quantum fields using rigorously defined Euclidean path integrals. We also comment on the infra-red problem in the AdS/CFT correspondence and argue that it is different from the usual IR problem in constructive quantum field theory. To illustrate this, a triviality proof based on hypercontractivity estimates is given for the case of an ultraviolet regularized potential of type: {phi}{sup 4}:. We also give a brief discussion on possible renormalization strategies and the specific problems that arise in this context. (orig.)

  15. 28 CFR 45.2 - Disqualification arising from personal or political relationship.

    Science.gov (United States)

    2010-07-01

    ... political relationship. 45.2 Section 45.2 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) EMPLOYEE RESPONSIBILITIES § 45.2 Disqualification arising from personal or political relationship. (a) Unless authorized under paragraph (b) of this section, no employee shall participate in a criminal investigation or...

  16. Problem solving in foundation engineering using foundationPro

    CERN Document Server

    Yamin, Mohammad

    2016-01-01

    This book is at once a supplement to traditional foundation engineering textbooks and an independent problem-solving learning tool. The book is written primarily for university students majoring in civil or construction engineering taking foundation analysis and design courses to encourage them to solve design problems. Its main aim is to stimulate problem solving capability and foster self-directed learning. It also explains the use of the foundationPro software, available at no cost, and includes a set of foundation engineering applications. Taking a unique approach, Dr. Yamin summarizes the general step-by-step procedure to solve various foundation engineering problems, illustrates traditional applications of these steps with longhand solutions, and presents the foundationPro solutions. The special structure of the book allows it to be used in undergraduate and graduate foundation design and analysis courses in civil and construction engineering. The book stands as valuable resource for students, faculty, ...

  17. Shape functions for separable solutions to cross-field diffusion problems

    International Nuclear Information System (INIS)

    Luning, C.D.; Perry, W.L.

    1984-01-01

    The shape function S(x), which arises in the study of nonlinear diffusion for cross-field diffusion in plasmas, satisfies the equation S''(x)+lambdaa(x)S/sup α/(x) = 0, 0 0. In the cases of physical interest a(x) possesses an integrable singularity at some point in (0,1) but is otherwise continuous. Existence of a positive solution to this problem is established

  18. Solving Large Scale Nonlinear Eigenvalue Problem in Next-Generation Accelerator Design

    Energy Technology Data Exchange (ETDEWEB)

    Liao, Ben-Shan; Bai, Zhaojun; /UC, Davis; Lee, Lie-Quan; Ko, Kwok; /SLAC

    2006-09-28

    A number of numerical methods, including inverse iteration, method of successive linear problem and nonlinear Arnoldi algorithm, are studied in this paper to solve a large scale nonlinear eigenvalue problem arising from finite element analysis of resonant frequencies and external Q{sub e} values of a waveguide loaded cavity in the next-generation accelerator design. They present a nonlinear Rayleigh-Ritz iterative projection algorithm, NRRIT in short and demonstrate that it is the most promising approach for a model scale cavity design. The NRRIT algorithm is an extension of the nonlinear Arnoldi algorithm due to Voss. Computational challenges of solving such a nonlinear eigenvalue problem for a full scale cavity design are outlined.

  19. Problems and challenges in social marketing.

    Science.gov (United States)

    Bloom, P N; Novelli, W D

    1981-01-01

    This article reviews the problems that arise when general marketing principles are applied to social programs. Social marketing is conceptualized as the design, implementation, and control of programs seeking to increase the acceptability of a social ideal or practice in a target group. These problems can occur in 8 basic decision-making areas: market analysis, market segmentation, product strategy development, pricing strategy development, channel strategy development, communications strategy development, organizational design and planning, and evaluation. Social marketers find that they have less good secondary data about their consumers, more problems obtaining valid and reliable measures of relevant variables, more difficulty sorting out the relative influence of determinants of consumer behavior, and more problems getting consumer research funded than marketers in the commercial sector. They tend to have less flexibility in shaping their products and more difficulty formulating product concepts. Problems associated with establishing, utilizing, and controlling distribution channels comprise another major difference between social and more conventional forms of marketing. Social marketers also find that their communications options are somewhat limited as a result of problems associated with use of paid advertisements, pressures not to use certain types of appeals in their messages, and the need to communicate large amounts of information in their messages. Moreover, social marketers must function in organizations where marketing activities are poorly understood, underappreciated, and inappropriately located. Finally, they face problems trying to define effectiveness measures or estimating the contribution their program has made toward the achievement of certain objectives. If all these problems are anticipated and handled creatively, social marketing efforts can succeed.

  20. A possible solution of the flavor problem and radiative neutrino masses

    Energy Technology Data Exchange (ETDEWEB)

    Adulpravitchai, Adisorn

    2010-06-23

    In this thesis, we discuss two important problems of the Standard Model of Particle Physics (SM), namely the flavor problem and the reason for the smallness of neutrino masses. The first one might be related to the origin of non-abelian discrete flavor symmetries. We discuss the possibility of obtaining them from an underlying continuous flavor symmetry, i.e. SU(2) or SU(3) through spontaneous symmetry breaking. Moreover, we investigate their possible origin from an orbifold compactification. We discuss all non-abelian discrete symmetries, which can arise from an orbifold T{sup 2}/Z{sub N}. They are A{sub 4}, S{sub 4}, D{sub 4}, D{sub 3}, and D{sub 6}. We present the idea of combining the breaking of an orbifold GUT and the flavor symmetry arising from the orbifold. We demonstrate the construction in a 6d SUSY SO(10) x S{sub 4}. For the second problem, we propose a one-loop neutrino mass model in the left-right symmetric framework. We observe the transmitted hierarchy from the charged lepton masses to the right-handed neutrino masses, which we call ''Radiative Transmission of Lepton Flavor Hierarchy''. Finally, we study the phenomenological aspects of the model such as lepton flavor violation (LFV), flavor number violation (FNV), and flavor changing neutral currents (FCNCs). (orig.)

  1. Statistical problems in nuclear regulation: introduction and overview

    International Nuclear Information System (INIS)

    Moore, R.H.; Easterling, R.G.

    1978-01-01

    The U.S. Nuclear Regulatory Commission (NRC) was organized formally in January 1975. The Commission's responsibilities can be categorized into four broad areas involving the licensing and use of nuclear materials and facilities: protecting public health and safety; protecting the environment; safeguarding nuclear materials and facilities; and assuring conformity with antitrust laws. A large variety of statistical problems are related to these basic responsibilities. They arise from the data-based nature of many of the issues to be resolved in making regulatory decisions. Hence, they are reflected in interactions among the NRC staff and licensees, vendors, and the public. This paper identifies and outlines some of these problems, providing a spectrum for comparison with the other presentations in this session. These problems are linked by the need for clear and objective treatment of data; their articulation and solution will benefit from insights and contributions from an informed statistical community

  2. Thermodynamic and chemical engineering problems arising with hybride processes

    International Nuclear Information System (INIS)

    Hunsaenger, K.

    1981-01-01

    Marginal parameters and definitions are set up for the NaK-NaKH cyclic process, the vapour-phase electrolysis on the basis of carbonates, high-temperature electrolysis using borax, the HCl/NaLiNO 3 cyclic process and the methane/methanol cyclic process. Such parameters and definitions are to create uniform conditions for the process design. (DG) [de

  3. A heuristics-based solution to the continuous berth allocation and crane assignment problem

    Directory of Open Access Journals (Sweden)

    Mohammad Hamdy Elwany

    2013-12-01

    Full Text Available Effective utilization plans for various resources at a container terminal are essential to reducing the turnaround time of cargo vessels. Among the scarcest resources are the berth and its associated cranes. Thus, two important optimization problems arise, which are the berth allocation and quay crane assignment problems. The berth allocation problem deals with the generation of a berth plan, which determines where and when a ship has to berth alongside the quay. The quay crane assignment problem addresses the problem of determining how many and which quay crane(s will serve each vessel. In this paper, an integrated heuristics-based solution methodology is proposed that tackles both problems simultaneously. The preliminary experimental results show that the proposed approach yields high quality solutions to such an NP-hard problem in a reasonable computational time suggesting its suitability for practical use.

  4. 28 CFR 68.53 - Review of an interlocutory order of an Administrative Law Judge in cases arising under section...

    Science.gov (United States)

    2010-07-01

    ... Administrative Law Judge in cases arising under section 274A or 274C. 68.53 Section 68.53 Judicial Administration... ADMINISTRATIVE LAW JUDGES IN CASES INVOLVING ALLEGATIONS OF UNLAWFUL EMPLOYMENT OF ALIENS, UNFAIR IMMIGRATION... Administrative Law Judge in cases arising under section 274A or 274C. (a) Authority. In a case arising under...

  5. Solitary fibrous tumor arising in an intrathoracic goiter

    DEFF Research Database (Denmark)

    Larsen, Stine Rosenkilde; Godballe, Christian; Krogdahl, Annelise

    2010-01-01

    . CONCLUSION: The histological appearance and immunohistochemical reaction pattern of SFT is characteristic. The entity should be considered when dealing with a spindle cell lesion in the thyroid gland. All cases of this site of origin reported have had a benign clinical course. As only a small number of cases......BACKGROUND: Solitary fibrous tumor (SFT) is a rare spindle cell tumor most often found in the mediastinal pleura. Nineteen cases of SFT arising in the thyroid gland have been reported. We report a case of SFT of the thyroid gland with immunohistochemical and cytogenetic investigation. SUMMARY: A 58...

  6. Convergence problems and energetic regions in π excited states of certain conjugated molecules

    International Nuclear Information System (INIS)

    Giambiagi, M.S. de; Giambiagi, M.; Barros, H.G. de P.L. de.

    1980-01-01

    When calculating π bond orders of excited and superexcited states of conjugated molecules, difficulties arise in applying the variation method; besides, the convergence problems involved are well known. For pyridazine, chosen for discussion, 27 states are considered; the convergence problem is envisaged through two criteria in the choice of a parameter introduced in the compromise Hamiltonian. This convergence parameter is related to the variation method. There exist three particular solutions for bond orders, which divide the 27 states into energetical regions. (Author) [pt

  7. The problems inherent in teaching technical writing and report writing to native Americans

    Science.gov (United States)

    Zukowski/faust, J.

    1981-01-01

    Teaching technical writing to Native Americans contending with a second language and culture is addressed. Learning difficulties arising from differences between native and acquired language and cultural systems are examined. Compartmentalized teaching, which presents the ideals of technical writing in minimal units, and skills development are considered. Rhetorical problems treated include logic of arrangement, selection of support and scope of detail, and time and space. Specific problems selected include the concept of promptness, the contextualization of purpose, interpersonal relationships, wordiness, mixture of registers, and the problem of abstracting. Four inductive procedures for students having writing and perception problems are included. Four sample exercises and a bibliography of 13 references are also included.

  8. Hepatocellular carcinoma arising from hepatocellular adenoma in a hepatitis B virus-associated cirrhotic liver

    International Nuclear Information System (INIS)

    Seo, J.M.; Lee, S.J.; Kim, S.H.; Park, C.K.; Ha, S.Y.

    2012-01-01

    Hepatocellular adenoma (HCA) is a rare, benign proliferation of hepatocytes that occurs mostly in a normal liver and in extreme rare cases, occurs in a cirrhotic liver. Hepatocellular carcinomas (HCC) arising within HCA through malignant transformation is rare. The specific incidence and mechanism of malignant transformation has not been established, but the long term use of oral contraceptives is considered a causative agent. We report a case of HCC arising from HCA detected in a hepatitis B-related cirrhotic liver with serial radiologic images.

  9. Hepatocellular carcinoma arising from hepatocellular adenoma in a hepatitis B virus-associated cirrhotic liver

    Energy Technology Data Exchange (ETDEWEB)

    Seo, J.M. [Department of Radiology and Center for Imaging Science, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul (Korea, Republic of); Lee, S.J., E-mail: lucia@skku.edu [Department of Radiology and Center for Imaging Science, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul (Korea, Republic of); Kim, S.H. [Department of Radiology and Center for Imaging Science, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul (Korea, Republic of); Park, C.K.; Ha, S.Y. [Department of Pathology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul (Korea, Republic of)

    2012-04-15

    Hepatocellular adenoma (HCA) is a rare, benign proliferation of hepatocytes that occurs mostly in a normal liver and in extreme rare cases, occurs in a cirrhotic liver. Hepatocellular carcinomas (HCC) arising within HCA through malignant transformation is rare. The specific incidence and mechanism of malignant transformation has not been established, but the long term use of oral contraceptives is considered a causative agent. We report a case of HCC arising from HCA detected in a hepatitis B-related cirrhotic liver with serial radiologic images.

  10. Diabetes mellitus type 1 as a health, nutriotial and social problem for children up to 18 years of age.

    OpenAIRE

    FRIDRICHOVSKÁ, Pavlína

    2011-01-01

    Work specifies the problems of children with diabetes mellitus type 1 - of site for health, in nutrition and social problems. The theoretical part is characterized by diabetes mellitus type 1, its causes, symptoms, treatment with diet and takes into account the specific problems arising from this condition for age. The practical part comprises the results of the questionnaire survey, which focuses on the problems of diabetes mellitus type 1 in childhood, and the level of knowledge about diabe...

  11. Analysis of Ineffectiveness Arising in “Investor-government” Relations

    Directory of Open Access Journals (Sweden)

    Dmytro B. Sokolovskyi

    2015-09-01

    Full Text Available Purpose: This article deals with the problem of forming Pareto non-optimal norms of mutual behavior of investors and government in the process of decision-making related to financing designed to reduce risks in investment activity. Methodology: Considering the interdependent type (nature of interactions between related parties, game theory tools were used to model such interactions. Much attention was directed to search for  parameters of interaction leading to certain Nash equilibriums in pure strategies. The formal results obtained with the model were verified by statistical analysis. Findings: Analysis showed that the rational behavior of related parties can lead to unexpected results. Powerful investors will aim to work in socially-oriented economies, whereas primarily small investors will operate in most liberal economies with a minimum tax burden but with a higher level of risk. As for governments’ behaviors, the images are the same: small economies tend to liberalize their tax systems and to secure investment faster than powerful ones. Empirical verification based on statistical data of groups of countries generally confirmed the conclusions. These formal and logical conclusions were from statistical analysis of 124 countries divided into 5 groups: OECD countries, post-socialist countries, Latin American countries, APAC countries and ACP countries. Provided that the more powerful ones are covered economies, there was stronger interdependence between the size of economies and tax burden and also between total investment and tax burden, where this dependence is positive. Originality: The results obtained used Nash equilibriums in pure strategies as models of behavioral norms to define behaviors of related parties and also to explain assumptions concerning the behaviors of investors and government.

  12. Lamin A/C mutation affecting primarily the right side of the heart

    Directory of Open Access Journals (Sweden)

    Laura Ollila

    2013-04-01

    Full Text Available LMNA mutations are amongst the most important causes of familial dilated cardiomyopathy. The most important cause of arrhythmogenic right ventricular cardiomyopathy (ARVC is desmosomal pathology. The aim of the study was to elucidate the role of LMNA mutations among Finnish cardiomyopathy patients. We screened 135 unrelated cardiomyopathy patients for LMNA mutations. Because of unusual phenotype, two patients were screened for the known Finnish ARVC-related mutations of desmosomal genes, and their Plakophilin-2b gene was sequenced. Myocardial samples from two patients were examined by immunohistochemical plakoglobin staining and in one case by electron microscopy. We found a new LMNA mutation Phe237Ser in a family of five affected members with a cardiomyopathy affecting primarily the right side of the heart. The phenotype resembles ARVC but does not fulfill the Task Force Criteria. The main clinical manifestations of the mutation were severe tricuspid insufficiency, right ventricular enlargement and failure. Three of the affected patients died of the heart disease, and the two living patients received heart transplants at ages 44 and 47. Electron microscopy showed nuclear blebbing compatible with laminopathy. Immunohisto - chemical analysis did not suggest desmosomal pathology. No desmosomal mutations were found. The Phe237Ser LMNA mutation causes a phenotype different from traditional cardiolaminopathy. Our findings suggest that cardiomyopathy affecting primarily the right side of the heart is not always caused by desmosomal pathology. Our observations highlight the challenges in classifying cardiomyopathies, as there often is significant overlap between the traditional categories.

  13. Melanotic paraganglioma arising in the temporal horn following Langerhans cell histiocytosis

    International Nuclear Information System (INIS)

    Yoo, Jeong Hyun; Rivera, Andreana; Naeini, Ramin M.; Yedururi, Sireesha; Megahead, Hatem; Bayindir, Petek; Fuller, Gregory N.; Suh, Jeong Soo; Adesina, Adekunle M.; Hunter, Jill V.

    2008-01-01

    Intracerebral paragangliomas are rare because of the lack of paraganglial cells in the cerebral tissue. We report a rare case of melanotic paraganglioma arising from the temporal horn of the lateral ventricle in a patient with prior Langerhans cell histiocytosis (LCH) treated with chemotherapy and radiation. (orig.)

  14. Concerning the problem of polygraphic wire calculation: theoretical aspects, software, practical implementation

    Directory of Open Access Journals (Sweden)

    Selkina A. V.

    2016-05-01

    Full Text Available the article analyzes the problems arising while organizing the workflow in printing companies. We suggest to address these problems by means of implementing computer-based accounting systems. Online and offline calculators used by printing enterprises for accounting are discussed. The author outlined the functional and specified requirements to such software. They were considered in the calculation module of accounting polygraphic wire used for block bonding. The software allows to increase the calculation process speed, to reduce the amount of errors in calculation and to decrease the labour intensity of the accounting process.

  15. Malignant mixed mullerian tumor arising from the uterine cervix: A case report

    International Nuclear Information System (INIS)

    Shim, Jong Joon; Shim, Jae Chan; Lee, Kyoung Eun; Lee, Ghi Jai; Kim, Ho Kyun; Suh, Jung Ho; Lee, Hye Kyung

    2012-01-01

    Malignant mixed mullerian tumors (MMMTs) are a rare uterine tumor and contribute to approximately 1-3% of all corpus malignant tumors. MMMTs are usually in the uterine corpus, but can also arise from the uterine cervix, vagina, ovaries and fallofian tubes. MMMTs of the uterine cervix are extremely rare. MMMTs are highly malignant and tend to maintain a rapid growth and exhibit a high rate of recurrence. Therefore, the prognosis of patients diagnosed with these types of tumors is extremely poor. We report a rare case of a malignant mixed mullerian tumor arising from the uterine cervix and introduce CT and MRI findings. CT and magnetic resonance findings of the uterine cervical MMMT in our case show highly aggressive features, such as parametrial involvement, pelvic and paraaortic lymphadenopathy, and distant metastasis and high enhancement

  16. Statistical physics of hard optimization problems

    International Nuclear Information System (INIS)

    Zdeborova, L.

    2009-01-01

    Optimization is fundamental in many areas of science, from computer science and information theory to engineering and statistical physics, as well as to biology or social sciences. It typically involves a large number of variables and a cost function depending on these variables. Optimization problems in the non-deterministic polynomial (NP)-complete class are particularly difficult, it is believed that the number of operations required to minimize the cost function is in the most difficult cases exponential in the system size. However, even in an NP-complete problem the practically arising instances might, in fact, be easy to solve. The principal question we address in this article is: How to recognize if an NP-complete constraint satisfaction problem is typically hard and what are the main reasons for this? We adopt approaches from the statistical physics of disordered systems, in particular the cavity method developed originally to describe glassy systems. We describe new properties of the space of solutions in two of the most studied constraint satisfaction problems - random satisfy ability and random graph coloring. We suggest a relation between the existence of the so-called frozen variables and the algorithmic hardness of a problem. Based on these insights, we introduce a new class of problems which we named ”locked” constraint satisfaction, where the statistical description is easily solvable, but from the algorithmic point of view they are even more challenging than the canonical satisfy ability.

  17. Statistical physics of hard optimization problems

    International Nuclear Information System (INIS)

    Zdeborova, L.

    2009-01-01

    Optimization is fundamental in many areas of science, from computer science and information theory to engineering and statistical physics, as well as to biology or social sciences. It typically involves a large number of variables and a cost function depending on these variables. Optimization problems in the non-deterministic polynomial-complete class are particularly difficult, it is believed that the number of operations required to minimize the cost function is in the most difficult cases exponential in the system size. However, even in an non-deterministic polynomial-complete problem the practically arising instances might, in fact, be easy to solve. The principal the question we address in the article is: How to recognize if an non-deterministic polynomial-complete constraint satisfaction problem is typically hard and what are the main reasons for this? We adopt approaches from the statistical physics of disordered systems, in particular the cavity method developed originally to describe glassy systems. We describe new properties of the space of solutions in two of the most studied constraint satisfaction problems - random satisfiability and random graph coloring. We suggest a relation between the existence of the so-called frozen variables and the algorithmic hardness of a problem. Based on these insights, we introduce a new class of problems which we named 'locked' constraint satisfaction, where the statistical description is easily solvable, but from the algorithmic point of view they are even more challenging than the canonical satisfiability (Authors)

  18. Statistical physics of hard optimization problems

    Science.gov (United States)

    Zdeborová, Lenka

    2009-06-01

    Optimization is fundamental in many areas of science, from computer science and information theory to engineering and statistical physics, as well as to biology or social sciences. It typically involves a large number of variables and a cost function depending on these variables. Optimization problems in the non-deterministic polynomial (NP)-complete class are particularly difficult, it is believed that the number of operations required to minimize the cost function is in the most difficult cases exponential in the system size. However, even in an NP-complete problem the practically arising instances might, in fact, be easy to solve. The principal question we address in this article is: How to recognize if an NP-complete constraint satisfaction problem is typically hard and what are the main reasons for this? We adopt approaches from the statistical physics of disordered systems, in particular the cavity method developed originally to describe glassy systems. We describe new properties of the space of solutions in two of the most studied constraint satisfaction problems - random satisfiability and random graph coloring. We suggest a relation between the existence of the so-called frozen variables and the algorithmic hardness of a problem. Based on these insights, we introduce a new class of problems which we named "locked" constraint satisfaction, where the statistical description is easily solvable, but from the algorithmic point of view they are even more challenging than the canonical satisfiability.

  19. Integrable equations, addition theorems, and the Riemann-Schottky problem

    International Nuclear Information System (INIS)

    Buchstaber, Viktor M; Krichever, I M

    2006-01-01

    The classical Weierstrass theorem claims that, among the analytic functions, the only functions admitting an algebraic addition theorem are the elliptic functions and their degenerations. This survey is devoted to far-reaching generalizations of this result that are motivated by the theory of integrable systems. The authors discovered a strong form of the addition theorem for theta functions of Jacobian varieties, and this form led to new approaches to known problems in the geometry of Abelian varieties. It is shown that strong forms of addition theorems arise naturally in the theory of the so-called trilinear functional equations. Diverse aspects of the approaches suggested here are discussed, and some important open problems are formulated.

  20. How do they solve it? An insight into the learner’s approach to the mechanism of physics problem solving

    OpenAIRE

    Balasubrahmanya Hegde; B. N. Meera

    2012-01-01

    A perceived difficulty is associated with physics problem solving from a learner’s viewpoint, arising out of a multitude of reasons. In this paper, we have examined the microstructure of students’ thought processes during physics problem solving by combining the analysis of responses to multiple-choice questions and semistructured student interviews. Design of appropriate scaffoldings serves as pointers to the identification of student problem solving difficulties. An analysis of the results ...

  1. Defining transmedia narrative: problems and questions. Dialogue with Mary-Laure Ryan

    Directory of Open Access Journals (Sweden)

    Franco Passalacqua

    2011-07-01

    Full Text Available In this interview Mary-Laure Ryan faces some problems that arise from her definition of «transmedia narrative». Can every semiotic system tell stories? How can we elaborate a definition of «narrative» which accounts both for cognitive and semantic aspects? How can we dispense with the syntactic level if we need a definition of «narrativity» that suits every semiotic system? Answering these questions, Ryan deals with other proposals developed around the same theoretical problems, and points out a thought-provoking argument against Meir Sternberg’s functionalist definition of narrative.

  2. The Problem of Time in Quantum Cosmology: A Decoherent Histories View

    International Nuclear Information System (INIS)

    Christodoulakis, Theodosios; Wallden, Petros

    2011-01-01

    The problem of time in quantum gravity arises due to the diffeomorphisms invariance of the theory and appears via the Hamiltonian constraint, in the canonical quantizations. There is a need for a description where one can ask some timeless questions that still encode some sense of temporality. The decoherent histories approach to quantum theory, already at the kinematical level admits an internal time. Several alternative proposals for resolving the problem of time via the decoherent histories, exist, and in this contribution we focus on one particular and examine how it manifests itself at some simple cosmological models.

  3. Nipple adenoma arising from axillary accessory breast: a case report

    Directory of Open Access Journals (Sweden)

    Shioi Yoshihiro

    2012-11-01

    Full Text Available Abstract Nipple adenoma is a relatively rare benign breast neoplasm, and cases of the disease arising from the axillary accessory breast have very seldom been reported in the English literature. We report a case of nipple adenoma arising from axillary accessory breast including clinical and pathological findings. An 82-year-old woman presented with the complaint of a small painful mass in the right axilla. Physical examination confirmed a well-defined eczematous crusted mass that was 8 mm in size. The diagnosis of nipple adenoma was made from an excisional specimen on the basis of characteristic histological findings. Microscopic structural features included a compact proliferation of small tubules lined by epithelial and myoepithelial cells, and the merging of glandular epithelial cells of the adenoma into squamous epithelial cells in the superficial epidermal layer. Because clinically nipple adenoma may resemble Paget’s disease and pathologically can be misinterpreted as tubular carcinoma, the correct identification of nipple adenoma is an important factor in the differential diagnosis for axillary tumor neoplasms. Virtual slides The virtual slide(s for this article can be found here: http://www.diagnosticpathology.diagnomx.eu/vs/1186821489769063

  4. The hydrogen anomaly problem in neutron Compton scattering

    Science.gov (United States)

    Karlsson, Erik B.

    2018-03-01

    Neutron Compton scattering (also called ‘deep inelastic scattering of neutrons’, DINS) is a method used to study momentum distributions of light atoms in solids and liquids. It has been employed extensively since the start-up of intense pulsed neutron sources about 25 years ago. The information lies primarily in the width and shape of the Compton profile and not in the absolute intensity of the Compton peaks. It was therefore not immediately recognized that the relative intensities of Compton peaks arising from scattering on different isotopes did not always agree with values expected from standard neutron cross-section tables. The discrepancies were particularly large for scattering on protons, a phenomenon that became known as ‘the hydrogen anomaly problem’. The present paper is a review of the discovery, experimental tests to prove or disprove the existence of the hydrogen anomaly and discussions concerning its origin. It covers a twenty-year-long history of experimentation, theoretical treatments and discussions. The problem is of fundamental interest, since it involves quantum phenomena on the subfemtosecond time scale, which are not visible in conventional thermal neutron scattering but are important in Compton scattering where neutrons have two orders of magnitude times higher energy. Different H-containing systems show different cross-section deficiencies and when the scattering processes are followed on the femtosecond time scale the cross-section losses disappear on different characteristic time scales for each H-environment. The last section of this review reproduces results from published papers based on quantum interference in scattering on identical particles (proton or deuteron pairs or clusters), which have given a quantitative theoretical explanation both regarding the H-cross-section reduction and its time dependence. Some new explanations are added and the concluding chapter summarizes the conditions for observing the specific quantum

  5. The Perceived Benefits and Problems Associated with Teaching Activities Undertaken by Doctoral Students

    Science.gov (United States)

    Jordan, Katy; Howe, Christine

    2018-01-01

    Postgraduate students involved in delivering undergraduate teaching while working toward a research degree are known as graduate teaching assistants (GTAs). This study focused upon the problems and benefits arising from this dual role as researchers and teachers, as perceived by GTAs at the University of Cambridge. To this end, GTAs at Cambridge…

  6. Shilajit: A panacea for high-altitude problems.

    Science.gov (United States)

    Meena, Harsahay; Pandey, H K; Arya, M C; Ahmed, Zakwan

    2010-01-01

    High altitude problems like hypoxia, acute mountain sickness, high altitude cerebral edema, pulmonary edema, insomnia, tiredness, lethargy, lack of appetite, body pain, dementia, and depression may occur when a person or a soldier residing in a lower altitude ascends to high-altitude areas. These problems arise due to low atmospheric pressure, severe cold, high intensity of solar radiation, high wind velocity, and very high fluctuation of day and night temperatures in these regions. These problems may escalate rapidly and may sometimes become life-threatening. Shilajit is a herbomineral drug which is pale-brown to blackish-brown, is composed of a gummy exudate that oozes from the rocks of the Himalayas in the summer months. It contains humus, organic plant materials, and fulvic acid as the main carrier molecules. It actively takes part in the transportation of nutrients into deep tissues and helps to overcome tiredness, lethargy, and chronic fatigue. Shilajit improves the ability to handle high altitudinal stresses and stimulates the immune system. Thus, Shilajit can be given as a supplement to people ascending to high-altitude areas so that it can act as a "health rejuvenator" and help to overcome high-altitude related problems.

  7. Minimization of Linear Functionals Defined on| Solutions of Large-Scale Discrete Ill-Posed Problems

    DEFF Research Database (Denmark)

    Elden, Lars; Hansen, Per Christian; Rojas, Marielba

    2003-01-01

    The minimization of linear functionals de ned on the solutions of discrete ill-posed problems arises, e.g., in the computation of con dence intervals for these solutions. In 1990, Elden proposed an algorithm for this minimization problem based on a parametric-programming reformulation involving...... the solution of a sequence of trust-region problems, and using matrix factorizations. In this paper, we describe MLFIP, a large-scale version of this algorithm where a limited-memory trust-region solver is used on the subproblems. We illustrate the use of our algorithm in connection with an inverse heat...

  8. On the Inclusion of Difference Equation Problems and Z Transform Methods in Sophomore Differential Equation Classes

    Science.gov (United States)

    Savoye, Philippe

    2009-01-01

    In recent years, I started covering difference equations and z transform methods in my introductory differential equations course. This allowed my students to extend the "classical" methods for (ordinary differential equation) ODE's to discrete time problems arising in many applications.

  9. Apocrine carcinoma arising in a complex fibroadenoma: a case report.

    Science.gov (United States)

    Mele, Marco; Vahl, Pernille; Funder, Jonas Amstrup; Sorensen, Anne Schmidt; Jensen, Vibeke

    2014-01-01

    A carcinoma arising in a fibroadenoma is a rare event, which often entails a diagnostic challenge. The most common type is the lobular carcinoma and secondary a ductal carcinoma. We present an extremely rare case of malignant development of an invasive apocrine carcinoma in a complex fibroadenoma and underline the importance for clinicians to recognize the possibility of benign and malignant co-existence especially in older women.

  10. Airborne iodine-125 arising from surface contamination

    International Nuclear Information System (INIS)

    Kwok, C.S.; Hilditch, T.E.

    1982-01-01

    Measurements of airborne 125 I were made during the subdivision of 740 MBq stocks of 125 I iodide solution in a hospital dispensary. Within the fume cupboard the mean airborne 125 I concentration was 3.5 +- 2.9 kBqm -3 . No airborne concentration contamination was found outside the fume cupboard during these dispensing sessions. The airborne 125 I concentration arising from deliberate surface contamination (50 μl, 3.7-6.3 MBq) of the top of a lead pot was measured at a height simulating face level at an open work bench. There was a progressive fall in airborne concentration over seven days but even then the level was still significantly above background. Measurements made with the extraction system of the fume cupboard in operation were 2-3 times lower. (U.K.)

  11. On the calculation of lattice sums arising in Bose-Einstein statistics of quasiparticle excitations

    International Nuclear Information System (INIS)

    Millev, Y.; Faehnle, M.

    1994-05-01

    A new method for the calculations of the average occupation number of bosonic quasi-particle excitations valid for any type of lattice is proposed. The method is based on the recognition of the connection with lattice Green's functions and generalized Watson integrals, on one hand, and on a very simple differentiation technique which renders unnecessary and artificial to this problem more sophisticated Laplace transform summation procedures. The mean-field approximation to Green's function theories of ferromagnetism arises naturally as the zeroth term in the obtained summation formulae. The results have been specified completely for the three cubic lattices. They are new for the simple cubic and face-centred cases, whereas certain redundancy is removed form the known body-centred cubic results. Applications of the method to more complex sums as, for instance, the thermodynamic sum for the total energy of the quasiparticles, are straightforward. There has also been found a new three-position recursion relation for the calculation of frequently occurring triple geometric integrals in the face-centred cubic case. It originates form a corresponding relation for a relevant Heun function. (author). 29 refs, 1 tab

  12. Focus point in gaugino mediation — Reconsideration of the fine-tuning problem

    Energy Technology Data Exchange (ETDEWEB)

    Yanagida, Tsutomu T.; Yokozaki, Norimi, E-mail: n.yokozaki@gmail.com

    2013-05-24

    We reconsider the fine-tuning problem in SUSY models, motivated by the recent observation of the relatively heavy Higgs boson and non-observation of the SUSY particles at the LHC. Based on this thought, we demonstrate a focus point-like behavior in a gaugino mediation model, and show that the fine-tuning is indeed reduced to about 2% level if the ratio of the gluino mass to wino mass is about 0.4 at the GUT scale. We show that such a mass ratio may arise naturally in a product group unification model without the doublet–triplet splitting problem. This fact suggests that the fine-tuning problem crucially depends on the physics at the high energy scale.

  13. The Online Specialization Problem

    Directory of Open Access Journals (Sweden)

    Ed Hong

    2006-01-01

    Full Text Available We study the online specialization problem, where items arrive in an online fashion for processing by one of n different methods. Each method has two costs: a processing cost (paid once for each item processed, and a set-up cost (paid only once, on the method's first use. There are n possible types of items; an item's type determines the set of methods available to process it. Each method has a different degree of specialization. Highly specialized methods can process few item types while generic methods may process all item types. This is a generalization of ski-rental and closely related to the capital investment problem of Y. Azar, Y. Bartal, E. Feuerstein, A. Fiat, S. Leonardi, and A. Rosen. On capital investment. In Algorithmica, 25(1:22-36, 1999. We primarily study the case where method i+1 is always more specialized than method i and the set-up cost for a more specialized method is always higher than that of a less specialized method. We describe an algorithm with competitive ratio O(log(n, and also show an Ω(log(n lower bound on the competitive ratio for this problem; this shows our ratio is tight up to constant factors.

  14. Hydrogen peroxide production is not primarily increased in human myotubes established from type 2 diabetic subjects.

    Science.gov (United States)

    Minet, A D; Gaster, M

    2011-09-01

    Increased oxidative stress and mitochondrial dysfunction have been implicated in the development of insulin resistance in type 2 diabetes. To date, it is unknown whether increased mitochondrial reactive oxygen species (ROS) production in skeletal muscle from patients with type 2 diabetes is primarily increased or a secondary adaptation to environmental, lifestyle, and hormonal factors. This study investigates whether ROS production is primarily increased in isolated diabetic myotubes. Mitochondrial membrane potential, hydrogen peroxide (H(2)O(2)), superoxide, and mitochondrial mass were determined in human myotubes precultured under normophysiological conditions. Furthermore, the corresponding ATP synthesis was measured in isolated mitochondria. Muscle biopsies were taken from 10 lean subjects, 10 obese subjects, and 10 subjects with type 2 diabetes; satellite cells were isolated, cultured, and differentiated to myotubes. Mitochondrial mass, membrane potential/mitochondrial mass, and superoxide-production/mitochondrial mass were not different between groups. In contrast, H(2)O(2) production/mitochondrial mass and ATP production were significantly reduced in diabetic myotubes compared to lean controls (P production is not primarily increased in diabetic myotubes but rather is reduced. Moreover, the comparable ATP/H(2)O(2) ratios indicate that the reduced ROS production in diabetic myotubes parallels the reduced ATP production because ROS production in diabetic myotubes must be considered to be in a proportion comparable to lean. Thus, the increased ROS production seen in skeletal muscle of type 2 diabetic patients is an adaptation to the in vivo conditions.

  15. Dealing with uncertainty arising out of probabilistic risk assessment

    International Nuclear Information System (INIS)

    Solomon, K.A.; Kastenberg, W.E.; Nelson, P.F.

    1984-03-01

    In addressing the area of safety goal implementation, the question of uncertainty arises. This report suggests that the Nuclear Regulatory Commission (NRC) should examine how other regulatory organizations have addressed the issue. Several examples are given from the chemical industry, and comparisons are made to nuclear power risks. Recommendations are made as to various considerations that the NRC should require in probabilistic risk assessments in order to properly treat uncertainties in the implementation of the safety goal policy. 40 references, 7 figures, 5 tables

  16. Language Problems and the Final Act. Esperanto Documents, New Series No. 11A.

    Science.gov (United States)

    Universal Esperanto Association, Rotterdam (Netherlands).

    The Final Act of the Conference on Security and Co-operation in Europe, linguistic problems in the way of cooperation, language differences and the potential for discriminatory practice, and the need for a new linguistic order are discussed. It is suggested that misunderstandings arising from differences of language reduce the ability of the 35…

  17. An Investigation of Starting Point Preferences in Human Performance on Traveling Salesman Problems

    Science.gov (United States)

    MacGregor, James N.

    2014-01-01

    Previous studies have shown that people start traveling sales problem tours significantly more often from boundary than from interior nodes. There are a number of possible reasons for such a tendency: first, it may arise as a direct result of the processes involved in tour construction; second, boundary points may be perceptually more salient than…

  18. Effectively Tackling Reinsurance Problems by Using Evolutionary and Swarm Intelligence Algorithms

    Directory of Open Access Journals (Sweden)

    Sancho Salcedo-Sanz

    2014-04-01

    Full Text Available This paper is focused on solving different hard optimization problems that arise in the field of insurance and, more specifically, in reinsurance problems. In this area, the complexity of the models and assumptions considered in the definition of the reinsurance rules and conditions produces hard black-box optimization problems (problems in which the objective function does not have an algebraic expression, but it is the output of a system (usually a computer program, which must be solved in order to obtain the optimal output of the reinsurance. The application of traditional optimization approaches is not possible in this kind of mathematical problem, so new computational paradigms must be applied to solve these problems. In this paper, we show the performance of two evolutionary and swarm intelligence techniques (evolutionary programming and particle swarm optimization. We provide an analysis in three black-box optimization problems in reinsurance, where the proposed approaches exhibit an excellent behavior, finding the optimal solution within a fraction of the computational cost used by inspection or enumeration methods.

  19. Analogy as a strategy for supporting complex problem solving under uncertainty.

    Science.gov (United States)

    Chan, Joel; Paletz, Susannah B F; Schunn, Christian D

    2012-11-01

    Complex problem solving in naturalistic environments is fraught with uncertainty, which has significant impacts on problem-solving behavior. Thus, theories of human problem solving should include accounts of the cognitive strategies people bring to bear to deal with uncertainty during problem solving. In this article, we present evidence that analogy is one such strategy. Using statistical analyses of the temporal dynamics between analogy and expressed uncertainty in the naturalistic problem-solving conversations among scientists on the Mars Rover Mission, we show that spikes in expressed uncertainty reliably predict analogy use (Study 1) and that expressed uncertainty reduces to baseline levels following analogy use (Study 2). In addition, in Study 3, we show with qualitative analyses that this relationship between uncertainty and analogy is not due to miscommunication-related uncertainty but, rather, is primarily concentrated on substantive problem-solving issues. Finally, we discuss a hypothesis about how analogy might serve as an uncertainty reduction strategy in naturalistic complex problem solving.

  20. Problems arising in connection with the commissioning of experts in conflict-oriented implementation of nuclear law. The legal status of expert opinions in administrative procedures under the Atomic Energy Act

    International Nuclear Information System (INIS)

    Fiebig, T.H.

    1995-01-01

    Court decisions available so far do not primarily consider the problems linked to the commissioning of an expert and his mandate, as well as the legal status of the commissioning of an expert as an administrative act which might be legally contestable. Thus there are at present no court decisions that would create legal certainty in matters of the act of commissioning a nuclear expert opinion. The current legal situation is such that an independent order for commissioning of an expert opinion in compliance with section 19 III AtG (Atomic Energy Act), which in general is given in response to the refusal of the facility operator to do so, can be independently contested on the basis of section 44 a, sentence 2 VwGO (Rules of Administrative Courts). The current practice of conflict-oriented, or nuclear power phase-out-oriented, implementation of the nuclear law poses a threat to our constitutional state and to our democracy. The supply of energy as a common good is of essential importance and thus deserves fair and objective treatment free of emotions, including the matter of nuclear energy. In cases of nuclear licensing procedures meeting with impedimental treatment by a Land government favouring the nuclear power phase-out, this treatment however not fitting into the Land governments' overall political line, there is reason to call upon the Federal Government to take action for clarifying the situation. (orig./HP) [de

  1. Where Cognitive Conflict Arises from?: The Structure of Creating Cognitive Conflict

    Science.gov (United States)

    Lee, Gyoungho; Yi, Jinseog

    2013-01-01

    In this study, our basic contention was that it is essential for researchers to answer the question, "Where does cognitive conflict really arise from?" with more precision than has heretofore been attempted. First, we examined how the term "cognitive conflict" has been treated in the existing literature and try to pinpoint some difficulties,…

  2. X-ray and CT signs of connective tissue dysplasia in patients with primarily diagnosed infiltrative pulmonary tuberculosis

    International Nuclear Information System (INIS)

    Sukhanova, L.A.; Sharmazanova, O.P.

    2009-01-01

    The x-ray signs of connective tissue systemic dysplasia (CTSD) in patients with primarily diagnosed pulmonary tuberculosis was investigated. Fifty-four patients (28 med and 26 women aged 18-70) with primarily diagnosed infiltrative pulmonary tuberculosis underwent x-ray study. In patients with infiltration pulmonary tuberculosis CTSD in the lungs manifests by their diminishing, deformity of the lung pattern, high position of the diaphragm cupola, mediastinum shift to the side of the pathology, which is better seen on CT. The degree of CTSD x-ray signs in the lungs depends on the number of phenotypical signs that is the degree of the disease manifestation. CT allows more accurate determining of the signs of connective tissue dysplasia in which tuberculosis develops

  3. Facial Cellulitis Arising from Dens Evaginatus: A Case Report

    Directory of Open Access Journals (Sweden)

    Chun-Ming Chen

    2005-07-01

    Full Text Available Dens evaginatus is a developmental anomaly that produces a tubercle on the occlusal surface of a tooth. It is found most frequently in the mandibular premolars. The occlusal tubercle easily causes occlusal interferences. Attrition or fracture of the tubercle can lead to pulpitis, pulp necrosis, periapical pathosis, and periapical infection. This case report illustrates the treatment of facial cellulitis arising from dens evaginatus with open apex. Calcium hydroxide was used for the apexification procedure. One year after canal obturation, radiography revealed no apical pathosis and the apical seal was evident.

  4. Building Language Through Conflict Resolution: Discussing Problems Enriches Language While Leading to Solutions

    Science.gov (United States)

    Church, Ellen Booth

    2005-01-01

    This brief article describes how classroom group time can be "talk central" for children to discuss problems, imagine solutions, even role-play hypothetical situations. It is often in the safety and support of the large group that children develop the tools they need to learn how to resolve the inevitable conflicts that arise throughout life.…

  5. Uniqueness in some higher order elliptic boundary value problems in n dimensional domains

    Directory of Open Access Journals (Sweden)

    C.-P. Danet

    2011-07-01

    Full Text Available We develop maximum principles for several P functions which are defined on solutions to equations of fourth and sixth order (including a equation which arises in plate theory and bending of cylindrical shells. As a consequence, we obtain uniqueness results for fourth and sixth order boundary value problems in arbitrary n dimensional domains.

  6. The Settlement of Litigations Arising from the Interpretation and Enforcement of Administrative Contracts

    Directory of Open Access Journals (Sweden)

    Vasilica NEGRUŢ

    2015-03-01

    Full Text Available Regarded nowadays as an instrument of strategy implementation of government policy and establishment mechanism of public administration, the administrative contract raises many debates on its applicable regime, but also on the jurisdiction, to solve litigations arising from their interpretation and execution. In this paper we proposed, based on the analysis of the laws in force, doctrine, jurisprudence, and previous research results related to the subject, using the comparative method, to clarify the mentioned issues. The conclusions of this paper will strengthen the practice on the referral of courts competent to solve litigations arising from the implementation of the administrative contracts in the context where the administrative contract has profound implications in the administrative, economic and social field.

  7. Primary Malignant Bone Tumours at the University Teaching ...

    African Journals Online (AJOL)

    Introduction: Primary malignant bone tumours include malignancies arising primarily from bone tissue. This is opposed to secondary bone tumours in which case the neoplastic elements arise primarily from other sites within the body and secondarily spread to bone. Primary malignant bone tumours are generally ...

  8. Using a videogame intervention to reduce anxiety and externalizing problems among youths in residential care: An initial randomized controlled trial

    NARCIS (Netherlands)

    Schuurmans, A.T.; Nijhof, K.S.; Engels, R.C.M.E.; Granic, I.

    2018-01-01

    Residential care is among the most intensive forms of treatment in youth care. It serves youths with severe behavioral problems and is primarily focused on targeting externalizing problems. Despite best efforts, effect sizes remain moderate, which may be due to the disregarding of internalizing

  9. An Open Challenge Problem Repository for Systems Supporting Binders

    OpenAIRE

    Felty, A.; Momigliano, A.; Pientka, B.

    2015-01-01

    A variety of logical frameworks support the use of higher-order abstract syntax in representing formal systems; however, each system has its own set of benchmarks. Even worse, general proof assistants that provide special libraries for dealing with binders offer a very limited evaluation of such libraries, and the examples given often do not exercise and stress-test key aspects that arise in the presence of binders. In this paper we design an open repository ORBI (Open challenge problem Repo...

  10. Modeling of problems of projection: A non-countercyclic approach

    Directory of Open Access Journals (Sweden)

    Jason Ginsburg

    2016-06-01

    Full Text Available This paper describes a computational implementation of the recent Problems of Projection (POP approach to the study of language (Chomsky 2013; 2015. While adopting the basic proposals of POP, notably with respect to how labeling occurs, we a attempt to formalize the basic proposals of POP, and b develop new proposals that overcome some problems with POP that arise with respect to cyclicity, labeling, and wh-movement operations. We show how this approach accounts for simple declarative sentences, ECM constructions, and constructions that involve long-distance movement of a wh-phrase (including the that-trace effect. We implemented these proposals with a computer model that automatically constructs step-by-step derivations of target sentences, thus making it possible to verify that these proposals work.

  11. Experimental bifurcation analysis—Continuation for noise-contaminated zero problems

    DEFF Research Database (Denmark)

    Schilder, Frank; Bureau, Emil; Santos, Ilmar Ferreira

    2015-01-01

    Noise contaminated zero problems involve functions that cannot be evaluated directly, but only indirectly via observations. In addition, such observations are affected by a non-deterministic observation error (noise). We investigate the application of numerical bifurcation analysis for studying...... the solution set of such noise contaminated zero problems, which is highly relevant in the context of equation-free analysis (coarse grained analysis) and bifurcation analysis in experiments, and develop specialized algorithms to address challenges that arise due to the presence of noise. As a working example......, we demonstrate and test our algorithms on a mechanical nonlinear oscillator experiment using control based continuation, which we used as a main application and test case for development of the Coco compatible Matlab toolbox Continex that implements our algorithms....

  12. A Riemann-Hilbert approach to the inverse problem for the Stark operator on the line

    Science.gov (United States)

    Its, A.; Sukhanov, V.

    2016-05-01

    The paper is concerned with the inverse scattering problem for the Stark operator on the line with a potential from the Schwartz class. In our study of the inverse problem, we use the Riemann-Hilbert formalism. This allows us to overcome the principal technical difficulties which arise in the more traditional approaches based on the Gel’fand-Levitan-Marchenko equations, and indeed solve the problem. We also produce a complete description of the relevant scattering data (which have not been obtained in the previous works on the Stark operator) and establish the bijection between the Schwartz class potentials and the scattering data.

  13. Existence theorem and optimality conditions for a class of convex semi-infinite problems with noncompact index sets

    Directory of Open Access Journals (Sweden)

    Olga Kostyukova

    2017-11-01

    Full Text Available The paper is devoted to study of a special class of semi-infinite problems arising in nonlinear parametric Semi-infinite Programming, when the differential properties of the solutions are being studied. These problems are convex and possess noncompact index sets. In the paper, we present conditions guaranteeing the existence of optimal solutions, and prove new optimality criterion. An example illustrating the obtained results is presented.

  14. Epithelioid sarcoma and squamous cell carcinoma arising in a burn scar

    Directory of Open Access Journals (Sweden)

    Kusum D Jashnani

    2011-01-01

    Full Text Available Development of a malignant tumor is a well known complication of a chronic burn scar. Most of these tumors are squamous cell carcinomas and only 28 cases of burn scar sarcomas have been reported in literature. We report the first occurrence of the combination of squamous cell carcinoma and epithelioid sarcoma arising in a burn scar.

  15. Aberrant ovarian artery arising from the common Iliac artery: Case report

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Won Kyung [Dept. of Radiology, Soonchunhyang University Bucheon Hospital, Soonchunhyang University College of Medicine, Bucheon (Korea, Republic of); Yang, Seung Boo; Lee, Jae Myeong [Dept. of Radiology, Soonchunhyang University Gumi Hospital, Soonchunhyang University College of Medicine, Gumi (Korea, Republic of); Goo, Dong Erk; Kim, Yong Jae; Chang, Yun Woo [Dept. of Radiology, Soonchunhyang University Seoul Hospital, Soonchunhyang University College of Medicine, Seoul (Korea, Republic of)

    2013-01-15

    A 46-year-old Vietnamese woman received embolization therapy in order to control postpartum hemorrhage. Angiography revealed an aberrant ovarian artery arising from the right common iliac artery. Superselective catheterization and subsequent embolization of the aberrant ovarian artery and bilateral uterine arteries were performed. Precise knowledge of the anatomic variations of the ovarian artery is important for successful embolization.

  16. Aberrant ovarian artery arising from the common Iliac artery: Case report

    International Nuclear Information System (INIS)

    Kim, Won Kyung; Yang, Seung Boo; Lee, Jae Myeong; Goo, Dong Erk; Kim, Yong Jae; Chang, Yun Woo

    2013-01-01

    A 46-year-old Vietnamese woman received embolization therapy in order to control postpartum hemorrhage. Angiography revealed an aberrant ovarian artery arising from the right common iliac artery. Superselective catheterization and subsequent embolization of the aberrant ovarian artery and bilateral uterine arteries were performed. Precise knowledge of the anatomic variations of the ovarian artery is important for successful embolization.

  17. Clear Cell Adenocarcinoma Arising from Abdominal Wall Endometriosis

    Directory of Open Access Journals (Sweden)

    Thouraya Achach

    2008-01-01

    Full Text Available Endometriosis is a frequent benign disorder. Malignancy arising in extraovarian endometriosis is a rare event. A 49-year-old woman is presented with a large painful abdominal wall mass. She underwent a myomectomy, 20 years before, for uterus leiomyoma. Computed tomography suggested that this was a desmoid tumor and she underwent surgery. Histological examination showed a clear cell adenocarcinoma associated with endometriosis foci. Pelvic ultrasound, computed tomography, and endometrial curettage did not show any malignancy or endometriosis in the uterus and ovaries. Adjuvant chemotherapy was recommended, but the patient was lost to follow up. Six months later, she returned with a recurrence of the abdominal wall mass. She was given chemotherapy and then she was reoperated.

  18. Some nonlinear problems in the manipulation of beams

    International Nuclear Information System (INIS)

    Sessler, A.M.

    1990-01-01

    An overview is given of nonlinear problems that arise in the manipulation of beams. Beams can be made of material particles or photons, can be intense or dilute, can be energetic or not, and they can be propagating in vacuum or in a medium. The nonlinear aspects of the motion are different in each case, and this diversity of behavior is categorized. Many examples are given, which serves to illustrate the categorization and, furthermore, display the richness of behavior encountered in the physics of beams. 25 refs., 5 figs

  19. Sensitivity computation of the l1 minimization problem and its application to dictionary design of ill-posed problems

    International Nuclear Information System (INIS)

    Horesh, L; Haber, E

    2009-01-01

    The l 1 minimization problem has been studied extensively in the past few years. Recently, there has been a growing interest in its application for inverse problems. Most studies have concentrated in devising ways for sparse representation of a solution using a given prototype dictionary. Very few studies have addressed the more challenging problem of optimal dictionary construction, and even these were primarily devoted to the simplistic sparse coding application. In this paper, sensitivity analysis of the inverse solution with respect to the dictionary is presented. This analysis reveals some of the salient features and intrinsic difficulties which are associated with the dictionary design problem. Equipped with these insights, we propose an optimization strategy that alleviates these hurdles while utilizing the derived sensitivity relations for the design of a locally optimal dictionary. Our optimality criterion is based on local minimization of the Bayesian risk, given a set of training models. We present a mathematical formulation and an algorithmic framework to achieve this goal. The proposed framework offers the design of dictionaries for inverse problems that incorporate non-trivial, non-injective observation operators, where the data and the recovered parameters may reside in different spaces. We test our algorithm and show that it yields improved dictionaries for a diverse set of inverse problems in geophysics and medical imaging

  20. Sensitivity computation of the ell1 minimization problem and its application to dictionary design of ill-posed problems

    Science.gov (United States)

    Horesh, L.; Haber, E.

    2009-09-01

    The ell1 minimization problem has been studied extensively in the past few years. Recently, there has been a growing interest in its application for inverse problems. Most studies have concentrated in devising ways for sparse representation of a solution using a given prototype dictionary. Very few studies have addressed the more challenging problem of optimal dictionary construction, and even these were primarily devoted to the simplistic sparse coding application. In this paper, sensitivity analysis of the inverse solution with respect to the dictionary is presented. This analysis reveals some of the salient features and intrinsic difficulties which are associated with the dictionary design problem. Equipped with these insights, we propose an optimization strategy that alleviates these hurdles while utilizing the derived sensitivity relations for the design of a locally optimal dictionary. Our optimality criterion is based on local minimization of the Bayesian risk, given a set of training models. We present a mathematical formulation and an algorithmic framework to achieve this goal. The proposed framework offers the design of dictionaries for inverse problems that incorporate non-trivial, non-injective observation operators, where the data and the recovered parameters may reside in different spaces. We test our algorithm and show that it yields improved dictionaries for a diverse set of inverse problems in geophysics and medical imaging.

  1. Nonlinear electric reaction arising in dry bone subjected to 4-point bending

    Science.gov (United States)

    Murasawa, Go; Cho, Hideo; Ogawa, Kazuma

    2007-04-01

    Bone is a smart, self-adaptive and also partly self-repairing tissue. In recent years, many researchers seek to find how to give the effective mechanical stimulation to bone, because it is the predominant loading that determines the bone shape and macroscopic structure. However, the trial of regeneration of bone is still under way. On the other hand, it has been known that electrical potential generates from bone by mechanical stimulation (Yasuda, 1977; Williams, 1982; Starkebaum, 1979; Cochran, 1968; Lanyon, 1977; Salzstein, 1987a,b; Friedenberg, 1966). This is called "stress-generated potential (SGP)". The process of information transfer between "strain" and "cells" is not still clear. But, there is some possibility that SGP has something to do with the process of information transfer. If the electrical potential is more clear under some mechanical loadings, we will be able to regenerate bone artificially and freely. Therefore, it is important to investigate SGP in detail. The aim of present study is to investigate the electric reaction arising in dry bone subjected to mechanical loadings at high amplitude and low frequency strain. Firstly, specimen is fabricated from femur of cow. Next, the speeds of wave propagation in bone are tried to measure by laser ultra sonic technique and wavelet transform, because these have relationship with bone density. Secondary, 4-point bending test is conducted up to fracture. Then, electric reaction arising in bone is measured during loading. Finally, cyclic 4-point bending tests are conducted to investigate the electric reaction arising in bone at low frequency strain.

  2. Fundamental problem in the relativistic approach to atomic structure theory

    International Nuclear Information System (INIS)

    Kagawa, Takashi

    1987-01-01

    It is known that the relativistic atomic structure theory contains a serious fundamental problem, so-called the Brown-Ravenhall (BR) problem or variational collapse. This problem arises from the fact that the energy spectrum of the relativistic Hamiltonian for many-electron systems is not bounded from below because the negative-energy solutions as well as the positive-energy ones are obtained from the relativistic equation. This report outlines two methods to avoid the BR problem in the relativistic calculation, that is, the projection operator method and the general variation method. The former method is described first. The use of a modified Hamiltonian containing a projection operator which projects the positive-energy solutions in the relativistic wave equation has been proposed to remove the BR difficulty. The problem in the use of the projection operator method is that the projection operator for the system cannot be determined uniquely. The final part of this report outlines the general variation method. This method can be applied to any system, such as relativistic ones whose Hamiltonian is not bounded from below. (Nogami, K.)

  3. Laplace transform homotopy perturbation method for the approximation of variational problems.

    Science.gov (United States)

    Filobello-Nino, U; Vazquez-Leal, H; Rashidi, M M; Sedighi, H M; Perez-Sesma, A; Sandoval-Hernandez, M; Sarmiento-Reyes, A; Contreras-Hernandez, A D; Pereyra-Diaz, D; Hoyos-Reyes, C; Jimenez-Fernandez, V M; Huerta-Chua, J; Castro-Gonzalez, F; Laguna-Camacho, J R

    2016-01-01

    This article proposes the application of Laplace Transform-Homotopy Perturbation Method and some of its modifications in order to find analytical approximate solutions for the linear and nonlinear differential equations which arise from some variational problems. As case study we will solve four ordinary differential equations, and we will show that the proposed solutions have good accuracy, even we will obtain an exact solution. In the sequel, we will see that the square residual error for the approximate solutions, belongs to the interval [0.001918936920, 0.06334882582], which confirms the accuracy of the proposed methods, taking into account the complexity and difficulty of variational problems.

  4. On the nucleon renormalization in many nucleon problems due to pionic degrees of freedom

    International Nuclear Information System (INIS)

    Sauer, P.U.; Sawicki, M.; Furui, Sadataka.

    1985-01-01

    Conceptual problems of unified two-nucleon force models are discussed. The force models are based on the pion-nucleon vertex and attempt a description of the nucleon-nucleon interaction below and above pion threshold. The conceptual problems arise from the nucleon renormalization due to pionic degrees of freedom. Keeping channels with a single pion only no renormalization procedure can be given which is consistent in the one-nucleon and in the many-nucleon systems. The medium dependence of the one-pion exchange potential is illustrated. (author)

  5. Problems of the π meson-nucleus interaction theory

    International Nuclear Information System (INIS)

    Kopaleishvili, T.I.

    1984-01-01

    The theory of multiple scattering as applied to PI-meson scattering on nuclei is outlined on the base of optical potential method: first in neglecting the real absorption of a pion by a nucleus and then for the case when this effect is taken into account. The pion interaction with a deuteron is considered both neglecting the pion absorption channel (the relativisitic problem of three bodies) and with account of the absorption channels and pion emission (in this case the problem is solved within the frames of the channel coupling theory for the pion-two nucleus system and the system of two nucleons). Approximate or model solutions to the problem of elastic pion-nuclear scattering primarily in the range of (3.3)-resonance are presented. The formulated theory permits to uniquely describe the observed processes caused by the strong pion interaction with a two-nucleon system

  6. Discrete quintic spline for boundary value problem in plate deflation theory

    Science.gov (United States)

    Wong, Patricia J. Y.

    2017-07-01

    We propose a numerical scheme for a fourth-order boundary value problem arising from plate deflation theory. The scheme involves a discrete quintic spline, and it is of order 4 if a parameter takes a specific value, else it is of order 2. We also present a well known numerical example to illustrate the efficiency of our method as well as to compare with other numerical methods proposed in the literature.

  7. Iterative Methods for Solving Nonlinear Parabolic Problem in Pension Saving Management

    Science.gov (United States)

    Koleva, M. N.

    2011-11-01

    In this work we consider a nonlinear parabolic equation, obtained from Riccati like transformation of the Hamilton-Jacobi-Bellman equation, arising in pension saving management. We discuss two numerical iterative methods for solving the model problem—fully implicit Picard method and mixed Picard-Newton method, which preserves the parabolic characteristics of the differential problem. Numerical experiments for comparison the accuracy and effectiveness of the algorithms are discussed. Finally, observations are given.

  8. Legal problems connected with irradiated fuel reprocessing and its waste storage

    International Nuclear Information System (INIS)

    Nercy, B. de.

    1981-10-01

    In view of its nature, an irradiated nuclear fuel reprocessing operation -and the contracts implementing it between the reprocessor and the customer- raises certain difficult legal problems. This paper analyses this question from the legal viewpoint, in particular as regards nuclear fuel and material ownership and products or waste arising therefrom, as well as in the context of rules of international trade and non-proliferation standards. (NEA) [fr

  9. Mesenchymal chondrosarcoma arising from the intrascrotal extratesicular soft tissue;a case report

    International Nuclear Information System (INIS)

    Lim, Jong-Uk; Koo, Bong-Sik; Park, Byeong-Ho; Park, Chang-Sook; Nam, Kyung-Jin; Kweon, Heon-Young

    2000-01-01

    Intrascrotal extratesticular malignancies are rare, and the radiologic findings of extraskeletal chondrosarcoma have not been reported. We describe the radiologic findings of a case of mesenchymal chondrosarcoma arising from intrascrotal extratesticular soft tissue and represented by a complex, cystic, solid mass containing calcifications and hematoma

  10. A problem with problem solving: motivational traits, but not cognition, predict success on novel operant foraging tasks.

    Science.gov (United States)

    van Horik, Jayden O; Madden, Joah R

    2016-04-01

    Rates of innovative foraging behaviours and success on problem-solving tasks are often used to assay differences in cognition, both within and across species. Yet the cognitive features of some problem-solving tasks can be unclear. As such, explanations that attribute cognitive mechanisms to individual variation in problem-solving performance have revealed conflicting results. We investigated individual consistency in problem-solving performances in captive-reared pheasant chicks, Phasianus colchicus , and addressed whether success depends on cognitive processes, such as trial-and-error associative learning, or whether performances may be driven solely via noncognitive motivational mechanisms, revealed through subjects' willingness to approach, engage with and persist in their interactions with an apparatus, or via physiological traits such as body condition. While subjects' participation and success were consistent within the same problems and across similar tasks, their performances were inconsistent across different types of task. Moreover, subjects' latencies to approach each test apparatus and their attempts to access the reward were not repeatable across trials. Successful individuals did not improve their performances with experience, nor were they consistent in their techniques in repeated presentations of a task. However, individuals that were highly motivated to enter the experimental chamber were more likely to participate. Successful individuals were also faster to approach each test apparatus and more persistent in their attempts to solve the tasks than unsuccessful individuals. Our findings therefore suggest that individual differences in problem-solving success can arise from inherent motivational differences alone and hence be achieved without inferring more complex cognitive processes.

  11. State-space models’ dirty little secrets: even simple linear Gaussian models can have estimation problems

    DEFF Research Database (Denmark)

    Auger-Méthé, Marie; Field, Chris; Albertsen, Christoffer Moesgaard

    2016-01-01

    problems. We demonstrate that these problems occur primarily when measurement error is larger than biological stochasticity, the condition that often drives ecologists to use SSMs. Using an animal movement example, we show how these estimation problems can affect ecological inference. Biased parameter......State-space models (SSMs) are increasingly used in ecology to model time-series such as animal movement paths and population dynamics. This type of hierarchical model is often structured to account for two levels of variability: biological stochasticity and measurement error. SSMs are flexible...

  12. Decision-making and problem-solving methods in automation technology

    Science.gov (United States)

    Hankins, W. W.; Pennington, J. E.; Barker, L. K.

    1983-01-01

    The state of the art in the automation of decision making and problem solving is reviewed. The information upon which the report is based was derived from literature searches, visits to university and government laboratories performing basic research in the area, and a 1980 Langley Research Center sponsored conferences on the subject. It is the contention of the authors that the technology in this area is being generated by research primarily in the three disciplines of Artificial Intelligence, Control Theory, and Operations Research. Under the assumption that the state of the art in decision making and problem solving is reflected in the problems being solved, specific problems and methods of their solution are often discussed to elucidate particular aspects of the subject. Synopses of the following major topic areas comprise most of the report: (1) detection and recognition; (2) planning; and scheduling; (3) learning; (4) theorem proving; (5) distributed systems; (6) knowledge bases; (7) search; (8) heuristics; and (9) evolutionary programming.

  13. Numerical stability in problems of linear algebra.

    Science.gov (United States)

    Babuska, I.

    1972-01-01

    Mathematical problems are introduced as mappings from the space of input data to that of the desired output information. Then a numerical process is defined as a prescribed recurrence of elementary operations creating the mapping of the underlying mathematical problem. The ratio of the error committed by executing the operations of the numerical process (the roundoff errors) to the error introduced by perturbations of the input data (initial error) gives rise to the concept of lambda-stability. As examples, several processes are analyzed from this point of view, including, especially, old and new processes for solving systems of linear algebraic equations with tridiagonal matrices. In particular, it is shown how such a priori information can be utilized as, for instance, a knowledge of the row sums of the matrix. Information of this type is frequently available where the system arises in connection with the numerical solution of differential equations.

  14. A penalty method for PDE-constrained optimization in inverse problems

    International Nuclear Information System (INIS)

    Leeuwen, T van; Herrmann, F J

    2016-01-01

    Many inverse and parameter estimation problems can be written as PDE-constrained optimization problems. The goal is to infer the parameters, typically coefficients of the PDE, from partial measurements of the solutions of the PDE for several right-hand sides. Such PDE-constrained problems can be solved by finding a stationary point of the Lagrangian, which entails simultaneously updating the parameters and the (adjoint) state variables. For large-scale problems, such an all-at-once approach is not feasible as it requires storing all the state variables. In this case one usually resorts to a reduced approach where the constraints are explicitly eliminated (at each iteration) by solving the PDEs. These two approaches, and variations thereof, are the main workhorses for solving PDE-constrained optimization problems arising from inverse problems. In this paper, we present an alternative method that aims to combine the advantages of both approaches. Our method is based on a quadratic penalty formulation of the constrained optimization problem. By eliminating the state variable, we develop an efficient algorithm that has roughly the same computational complexity as the conventional reduced approach while exploiting a larger search space. Numerical results show that this method indeed reduces some of the nonlinearity of the problem and is less sensitive to the initial iterate. (paper)

  15. How do they solve it? An insight into the learner’s approach to the mechanism of physics problem solving

    Directory of Open Access Journals (Sweden)

    Balasubrahmanya Hegde

    2012-03-01

    Full Text Available A perceived difficulty is associated with physics problem solving from a learner’s viewpoint, arising out of a multitude of reasons. In this paper, we have examined the microstructure of students’ thought processes during physics problem solving by combining the analysis of responses to multiple-choice questions and semistructured student interviews. Design of appropriate scaffoldings serves as pointers to the identification of student problem solving difficulties. An analysis of the results suggests the necessity of identification of the skill sets required for developing better problem solving abilities.

  16. Technological problems connected with execution of the protection sheets for nuclear power sets WWER-1000

    International Nuclear Information System (INIS)

    Hajutin, J.G.; Kriczewskij, A.Z.

    1977-01-01

    The choice of the structure and the prestressing system of the R.C. protection sheet for nuclear power sets WWER-1000 is motivated. The technological problems arised during the execution stage, as well as the technological line producing the tendons to prestress the structure by up winding are presented. (author)

  17. An Efficient Heuristic Approach for Irregular Cutting Stock Problem in Ship Building Industry

    Directory of Open Access Journals (Sweden)

    Yan-xin Xu

    2016-01-01

    Full Text Available This paper presents an efficient approach for solving a real two-dimensional irregular cutting stock problem in ship building industry. Cutting stock problem is a common cutting and packing problem that arises in a variety of industrial applications. A modification of selection heuristic Exact Fit is applied in our research. In the case referring to irregular shapes, a placement heuristics is more important to construct a complete solution. A placement heuristic relating to bottom-left-fill is presented. We evaluate the proposed approach using generated instance only with convex shapes in literatures and some instances with nonconvex shapes based on real problem from ship building industry. The results demonstrate that the effectiveness and efficiency of the proposed approach are significantly better than some conventional heuristics.

  18. Techniques of treatment or conditioning for waste arising from 131I production

    International Nuclear Information System (INIS)

    Dellamono, J.C.

    1989-07-01

    Distillation, evaporation/crystallization, direct immobilization and some chemical like precipitation and reduction were studied as techniques of treatment or conditioning for waste arising from 131 I production. The description of all techniques studied, as well as evaluation and discussion of the results are presented. (author) [pt

  19. Evaluation of environmental impacts arising from uranium extraction in Lagoa Real Bahia

    Energy Technology Data Exchange (ETDEWEB)

    Oliveira, Suzicleide L.; Thibes, Ronaldo; Campos, Simara S., E-mail: suzilopes@ig.com.br, E-mail: thibes@uesb.edu.br, E-mail: simaracampos@gmail.com [Universidade Estadual do Sudoeste da Bahia (UESB), Itapetinga, BA (Brazil)

    2013-07-01

    Since the beginnings of the industrial era, there has been an increasing use of fossil fuels, causing a rising of about 30% in the level of carbon dioxide concentrations and, consequently, elevating the global temperature. In the present days, we witness a huge worldwide concern about the generation of energy without emitting polluting gases responsible for the global warming, the so called clean energy. In this way, nuclear energy has reemerged as an important efficient means for generating domestic and industrial energy without producing the toxic greenhouse effect gases. Brazil is one of the current highest economic developing countries, with various internal sectors demanding more and more new technologies and energy consumption. Although traditionally Brazil has lain mainly on hydric resources, nuclear energy appears as real option in the current scenario. In the present work we analyse uranium extraction and processing in the Brazilian Region of Lagoa Real Bahia. In the recent literature, there has appeared some localized works, analyzing environmental impacts arising from the uranium extraction in that region. Based on data collection and analysis of soil, water and teeth, these works represent a first effort in the environmental impacts issue. Building upon published technical results we aim at a global understanding of the problem. Considering such different data sets, we look for global answers relating general aspects of the uranium extraction in the region. We present a comparative study, stressing connections and pointing ou different aspects of the common environmental issue. (author)

  20. Evaluation of environmental impacts arising from uranium extraction in Lagoa Real Bahia

    International Nuclear Information System (INIS)

    Oliveira, Suzicleide L.; Thibes, Ronaldo; Campos, Simara S.

    2013-01-01

    Since the beginnings of the industrial era, there has been an increasing use of fossil fuels, causing a rising of about 30% in the level of carbon dioxide concentrations and, consequently, elevating the global temperature. In the present days, we witness a huge worldwide concern about the generation of energy without emitting polluting gases responsible for the global warming, the so called clean energy. In this way, nuclear energy has reemerged as an important efficient means for generating domestic and industrial energy without producing the toxic greenhouse effect gases. Brazil is one of the current highest economic developing countries, with various internal sectors demanding more and more new technologies and energy consumption. Although traditionally Brazil has lain mainly on hydric resources, nuclear energy appears as real option in the current scenario. In the present work we analyse uranium extraction and processing in the Brazilian Region of Lagoa Real Bahia. In the recent literature, there has appeared some localized works, analyzing environmental impacts arising from the uranium extraction in that region. Based on data collection and analysis of soil, water and teeth, these works represent a first effort in the environmental impacts issue. Building upon published technical results we aim at a global understanding of the problem. Considering such different data sets, we look for global answers relating general aspects of the uranium extraction in the region. We present a comparative study, stressing connections and pointing ou different aspects of the common environmental issue. (author)

  1. Management of Large Volumes of Waste Arising in a Nuclear or Radiological Emergency

    International Nuclear Information System (INIS)

    2017-10-01

    This publication, prepared in light of the IAEA Action Plan on Nuclear Safety developed after the accident at the Fukushima Daiichi nuclear power plant, addresses the management of large volumes of radioactive waste arising in a nuclear or radiological emergency, as part of overall emergency preparedness. The management of large volumes of waste will be one of many efforts to be dealt with to allow recovery of affected areas, to support return of evacuated or relocated populations and preparations for normal social and economic activities, and/or to mitigate additional environmental impacts. The publication is intended to be of use to national planners and policy makers, facility and programme managers, and other professionals responsible for developing and implementing national plans and strategies to manage radioactive waste arising from nuclear or radiological emergencies.

  2. Fuzzy Portfolio Selection Problem with Different Borrowing and Lending Rates

    OpenAIRE

    Chen, Wei; Yang, Yiping; Ma, Hui

    2011-01-01

    As we know, borrowing and lending risk-free assets arise extensively in the theory and practice of finance. However, little study has ever investigated them in fuzzy portfolio problem. In this paper, the returns of each assets are assumed to be fuzzy variables, then following the mean-variance approach, a new possibilistic portfolio selection model with different interest rates for borrowing and lending is proposed, in which the possibilistic semiabsolute deviation of the return is used to...

  3. The Offshore Wind Farm Array Cable Layout Problem

    DEFF Research Database (Denmark)

    Bauer, Joanna; Lysgaard, Jens

    2014-01-01

    In an offshore wind farm (OWF), the turbines are connected to a transformer by cable routes that cannot cross each other. Finding the minimum cost array cable layout thus amounts to a vehicle routing problem with the additional constraints that the routes must be embedded in the plane. For this p......In an offshore wind farm (OWF), the turbines are connected to a transformer by cable routes that cannot cross each other. Finding the minimum cost array cable layout thus amounts to a vehicle routing problem with the additional constraints that the routes must be embedded in the plane....... For this problem, both exact and heuristic methods are of interest. We optimize cable layouts for real-world OWFs by a hop-indexed integer programming formulation, and develop a heuristic for computing layouts based on the Clarke and Wright savings heuristic for vehicle routing. Our heuristic computes layouts...... on average only 2% more expensive than the optimal layout. Finally, we present two problem extensions arising from real-world OWF cable layouts, and adapt the integer programming formulation to one of them. The thus obtained optimal layouts are up to 13% cheaper than the actually installed layouts....

  4. Arthroscopic Resection of Wrist Ganglion Arising from the Lunotriquetral Joint

    OpenAIRE

    Mak, Michael C. K.; Ho, Pak-cheong; Tse, W. L.; Wong, Clara W. Y.

    2013-01-01

    The dorsal wrist ganglion is the most common wrist mass, and previous studies have shown that it arises from the scapholunate interval in the vast majority of cases. Treatment has traditionally been open excision, and more recently arthroscopic resection has been established as an effective and less invasive treatment method. However, application of this technique to ganglia in atypical locations has not been reported, where open excision is the usual practice. This report describes two cases...

  5. Management of radioactive solid waste arisings from PFR reprocessing

    International Nuclear Information System (INIS)

    Allardice, R.H.; Hackney, S.; Bailey, G.; Bremner, W.; Lillyman, E.; Pugh, O.; Reekie, J.

    1982-01-01

    A description is given of the solid radioactive waste management facilities for dealing with the arisings from PFR reprocessing at the Dounreay Nuclear Power Development Establishment. Four major categories of solid waste are identified. The 'La Calhene' posting system for the transfer of active wastes which has been installed is discussed. The three new retrievable stores for high α#betta##betta#, high α low #betta##betta# and low α high #betta##betta# are described. The methods of waste categorisation by non-destructive assay techniques are outlined. Finally a review of operating experience with the facilities is presented. (U.K.)

  6. Electrical circuits in biomedical engineering problems with solutions

    CERN Document Server

    Keskin, Ali Ümit

    2017-01-01

    This authored monograph presents a comprehensive and in-depth analysis of electrical circuit theory in biomedical engineering, ideally suited as textbook for a course program. The book contains methods and theory, but the topical focus is placed on practical applications of circuit theory, including problems, solutions and case studies. The target audience primarily comprises researchers and experts in electrical engineering who intend to embark on biomedical applications. The book is also very well suited for graduate students in the field. .

  7. A Large Cystic Variant of Gastro-intestinal Stromal Tumour arising from the Jejunum: A Case Report

    OpenAIRE

    Shaikh, Salman Tehran; Upwanshi, Manish Harinarayan; Shetty, Tilakdas S.; Ghetla, Smruti R.; Gheewala, Hussain

    2015-01-01

    Gastrointestinal stromal tumours (GISTs) represent a mesenchymal neoplasm arising from the interstitial cells of cajal occurring mainly in the gastrointestinal tract. Here, we present a case of a large GIST arising from the jejunum with cystic presentation unlike the usual presentation as a solid mass. A 50-year-old male patient came with complaint of a painless mobile lump in abdomen of approximately 25 cm in size which had gradually increased over two years. Clinically mesenteric cyst was s...

  8. Formal language constrained path problems

    Energy Technology Data Exchange (ETDEWEB)

    Barrett, C.; Jacob, R.; Marathe, M.

    1997-07-08

    In many path finding problems arising in practice, certain patterns of edge/vertex labels in the labeled graph being traversed are allowed/preferred, while others are disallowed. Motivated by such applications as intermodal transportation planning, the authors investigate the complexity of finding feasible paths in a labeled network, where the mode choice for each traveler is specified by a formal language. The main contributions of this paper include the following: (1) the authors show that the problem of finding a shortest path between a source and destination for a traveler whose mode choice is specified as a context free language is solvable efficiently in polynomial time, when the mode choice is specified as a regular language they provide algorithms with improved space and time bounds; (2) in contrast, they show that the problem of finding simple paths between a source and a given destination is NP-hard, even when restricted to very simple regular expressions and/or very simple graphs; (3) for the class of treewidth bounded graphs, they show that (i) the problem of finding a regular language constrained simple path between source and a destination is solvable in polynomial time and (ii) the extension to finding context free language constrained simple paths is NP-complete. Several extensions of these results are presented in the context of finding shortest paths with additional constraints. These results significantly extend the results in [MW95]. As a corollary of the results, they obtain a polynomial time algorithm for the BEST k-SIMILAR PATH problem studied in [SJB97]. The previous best algorithm was given by [SJB97] and takes exponential time in the worst case.

  9. A randomized trial of a DWI intervention program for first offenders: intervention outcomes and interactions with antisocial personality disorder among a primarily American-Indian sample.

    Science.gov (United States)

    Woodall, W Gill; Delaney, Harold D; Kunitz, Stephen J; Westerberg, Verner S; Zhao, Hongwei

    2007-06-01

    Randomized trial evidence on the effectiveness of incarceration and treatment of first-time driving while intoxicated (DWI) offenders who are primarily American Indian has yet to be reported in the literature on DWI prevention. Further, research has confirmed the association of antisocial personality disorder (ASPD) with problems with alcohol including DWI. A randomized clinical trial was conducted, in conjunction with 28 days of incarceration, of a treatment program incorporating motivational interviewing principles for first-time DWI offenders. The sample of 305 offenders including 52 diagnosed as ASPD by the Diagnostic Interview Schedule were assessed before assignment to conditions and at 6, 12, and 24 months after discharge. Self-reported frequency of drinking and driving as well as various measures of drinking over the preceding 90 days were available at all assessments for 244 participants. Further, DWI rearrest data for 274 participants were available for analysis. Participants randomized to receive the first offender incarceration and treatment program reported greater reductions in alcohol consumption from baseline levels when compared with participants who were only incarcerated. Antisocial personality disorder participants reported heavier and more frequent drinking but showed significantly greater declines in drinking from intake to posttreatment assessments. Further, the treatment resulted in larger effects relative to the control on ASPD than non-ASPD participants. Nonconfrontational treatment may significantly enhance outcomes for DWI offenders with ASPD when delivered in an incarcerated setting, and in the present study, such effects were found in a primarily American-Indian sample.

  10. Use of paired management action grids for ease in depicting differences between users' and managers' perceptions of problems

    Science.gov (United States)

    R. J. Steele; James E. Fletcher

    1992-01-01

    This research was to determine whether differences exist between users and managers concerning perceptions of actual and perceived problems in parks and primarily to present a method of graphically depicting the differing perceptions of problems which exist between users and park managers which can be easily employed by area managers and related to the public, upper...

  11. Some problems in the technique of high-voltage testing of the accelerating tube gaps in electrostatic accelerators

    International Nuclear Information System (INIS)

    Romanov, V.A.; Ivanov, V.V.; Mukhametshin, V.I.; Dmitriev, E.P.; Kidalov, A.I.

    1983-01-01

    Problems arising during high-voltage testing and training of accelerating taubes of electrostatic accelrators are discussed. A rig and technique of the accelerating tube testing and program designed for the processing of the data obtained and sorting out of the samples investigated are described

  12. Multigrid Algorithms for the Solution of Linear Complementarity Problems Arising from Free Boundary Problems.

    Science.gov (United States)

    1980-10-01

    solving (1.3); PFAS combines the concepts of multigrid algorithms with those of projected SOR. In Section 3, we discuss the implementation of PFAS, and...numerique de la torsion elasto- plastique d’une barre cylindrique. In Approximation et Methodes Iteratives de Resolution d’Inequations Variationelles et

  13. First-Order Hyperbolic System Method for Time-Dependent Advection-Diffusion Problems

    Science.gov (United States)

    2014-03-01

    accuracy, with rapid convergence over each physical time step, typically less than five Newton iter - ations. 1 Contents 1 Introduction 3 2 Hyperbolic...however, we employ the Gauss - Seidel (GS) relaxation, which is also an O(N) method for the discretization arising from hyperbolic advection-diffusion system...advection-diffusion scheme. The linear dependency of the iterations on Table 1: Boundary layer problem ( Convergence criteria: Residuals < 10−8.) log10Re

  14. Setting up problems raised by construction of the EDF-Eurodif complex

    International Nuclear Information System (INIS)

    Fontaine, J.P.; Roux, J.P.

    1977-01-01

    After presentation of the Tricastin site and the nuclear complex to be built there, the main problems of social, economical or administrative order arising from the establishment of the site are analyzed and the solutions applied in order to overcome them are described. In conclusion they note that the largest site in Europe should be carried out up to completion in the best interests of local collectivities, of the Engineers and the populations concerned [fr

  15. Assessment of radioactive residues arising from radiolabel instability in a multiple dose tissue distribution study in rats

    International Nuclear Information System (INIS)

    Slatter, J.G.; Sams, J.P.; Easter, J.A.

    2003-01-01

    Our study objectives were to quantitatively determine the effect of radiolabel instability on terminal phase radioactive tissue residues in a multiple dose tissue distribution study, to quantitatively compare tissue residue artifacts (non drug-related radioactivity) from two chemically-distinct radiolabel locations, and to conduct a definitive multiple dose tissue distribution study using the better of the two radiolabeled compounds. We compared the excretion and tissue distribution in rats of [ 14 C]linezolid, radiolabeled in two different locations, after 7 consecutive once daily [ 14 C] oral doses. The radiolabels were in the acetamide (two carbon) and oxazolidinone (isolated carbon) functional groups. Terminal phase tissue residue and excretion data were compared to data from rats dosed orally with [ 14 C]sodium acetate. Drug-related radioactivity was excreted rapidly over 24 h. After a single dose, the acetamide and oxazolidinone radiolabel sites both gave 3% of dose as exhaled 14 CO 2 . After 7 daily [ 14 C] oral doses, terminal phase radioactive tissue residues were higher from the acetamide radiolabel, relative to the oxazolidinone radiolabel, and were primarily not drug-related. In the definitive tissue distribution study, low concentrations of drug-related radioactivity in skin and thyroid were observed. We conclude that although small amounts of radiolabel instability do not significantly affect single dose tissue radioactivity C max and area under the curve (AUC), artifacts arising from radiolabel instability can prolong the apparent terminal phase half life and complicate study data interpretation. When possible, it is always preferable to use a completely stable radiolabel site. (author)

  16. Assessment of radioactive residues arising from radiolabel instability in a multiple dose tissue distribution study in rats

    Energy Technology Data Exchange (ETDEWEB)

    Slatter, J.G. [Pharmacia Corp., Peapack, NJ (United States); Sams, J.P.; Easter, J.A. [Pharmacia Corp., Kalamazoo, MI (United States)] [and others

    2003-05-01

    Our study objectives were to quantitatively determine the effect of radiolabel instability on terminal phase radioactive tissue residues in a multiple dose tissue distribution study, to quantitatively compare tissue residue artifacts (non drug-related radioactivity) from two chemically-distinct radiolabel locations, and to conduct a definitive multiple dose tissue distribution study using the better of the two radiolabeled compounds. We compared the excretion and tissue distribution in rats of [{sup 14}C]linezolid, radiolabeled in two different locations, after 7 consecutive once daily [{sup 14}C] oral doses. The radiolabels were in the acetamide (two carbon) and oxazolidinone (isolated carbon) functional groups. Terminal phase tissue residue and excretion data were compared to data from rats dosed orally with [{sup 14}C]sodium acetate. Drug-related radioactivity was excreted rapidly over 24 h. After a single dose, the acetamide and oxazolidinone radiolabel sites both gave 3% of dose as exhaled {sup 14}CO{sub 2}. After 7 daily [{sup 14}C] oral doses, terminal phase radioactive tissue residues were higher from the acetamide radiolabel, relative to the oxazolidinone radiolabel, and were primarily not drug-related. In the definitive tissue distribution study, low concentrations of drug-related radioactivity in skin and thyroid were observed. We conclude that although small amounts of radiolabel instability do not significantly affect single dose tissue radioactivity C{sub max} and area under the curve (AUC), artifacts arising from radiolabel instability can prolong the apparent terminal phase half life and complicate study data interpretation. When possible, it is always preferable to use a completely stable radiolabel site. (author)

  17. Iterative methods for the detection of Hopf bifurcations in finite element discretisation of incompressible flow problems

    International Nuclear Information System (INIS)

    Cliffe, K.A.; Garratt, T.J.; Spence, A.

    1992-03-01

    This paper is concerned with the problem of computing a small number of eigenvalues of large sparse generalised eigenvalue problems arising from mixed finite element discretisations of time dependent equations modelling viscous incompressible flow. The eigenvalues of importance are those with smallest real part and can be used in a scheme to determine the stability of steady state solutions and to detect Hopf bifurcations. We introduce a modified Cayley transform of the generalised eigenvalue problem which overcomes a drawback of the usual Cayley transform applied to such problems. Standard iterative methods are then applied to the transformed eigenvalue problem to compute approximations to the eigenvalue of smallest real part. Numerical experiments are performed using a model of double diffusive convection. (author)

  18. Correction of Proofs in "Purely Infinite Simple C*-algebras Arising from Free Product Constructions'' and a Subsequent Paper

    DEFF Research Database (Denmark)

    Ara, Pere; Dykema, Kenneth J.; Rørdam, Mikael

    2013-01-01

    The proofs of Theorem 2.2 of K. J. Dykema and M. Rørdam, Purely infinite simple C∗-algebras arising from free product constructions}, Canad. J. Math. 50 (1998), 323--341 and of Theorem 3.1 of K. J. Dykema, Purely infinite simple C∗-algebras arising from free product constructions, II, Math. Scand...

  19. Free boundary problems in PDEs and particle systems

    CERN Document Server

    Carinci, Gioia; Giardinà, Cristian; Presutti, Errico

    2016-01-01

    In this volume a theory for models of transport in the presence of a free boundary is developed. Macroscopic laws of transport are described by PDE's. When the system is open, there are several mechanisms to couple the system with the external forces. Here a class of systems where the interaction with the exterior takes place in correspondence of a free boundary is considered. Both continuous and discrete models sharing the same structure are analysed. In Part I a free boundary problem related to the Stefan Problem is worked out in all details. For this model a new notion of relaxed solution is proposed for which global existence and uniqueness is proven. It is also shown that this is the hydrodynamic limit of the empirical mass density of the associated particle system. In Part II several other models are discussed. The expectation is that the results proved for the basic model extend to these other cases. All the models discussed in this volume have an interest in problems arising in several research fields...

  20. Stress cardiomyopathy: Is it limited to Takotsubo syndrome? Problems of definition.

    Science.gov (United States)

    Sarapultsev, Petr A; Sarapultsev, Alexey P

    2016-10-15

    In 2006, Takotsubo syndrome (TTC) was described as a distinct type of stress-induced cardiomyopathy (stress cardiomyopathy). However, when thinking about Takotsubo cardiomyopathy from the viewpoints of the AHA and ESC classifications, 2 possible problems may arise. The first potential problem is that a forecast of disease outcome is lacking in the ESC classification, whereas the AHA only states that 'outcome is favorable with appropriate medical therapy'. However, based on the literature data, one can make a general conclusion that occurrence of myocardial lesions in TTC (i.e., myocardial fibrosis and contraction-band necrosis) causes the same effects as in other diseases with similar levels of myocardial damage and should not be considered to have a lesser impact on mortality. To summarise, TTC can cause not only severe complications such as pulmonary oedema, cardiogenic shock, and dangerous ventricular arrhythmias, but also damage to the myocardium, which can result in the development of potentially fatal conditions even after the disappearance of LV apical ballooning. The second potential problem arises from the definition of TTC as a stress cardiomyopathy in the AHA classification. In fact, the main factors leading to TTC are stress and microvascular anginas, since, as has been already discussed, coronary spasm can cause myocardium stunning, resulting in persistent apical ballooning. Thus, based on this review, 3 distinct types of stress cardiomyopathies exist (variant angina, microvascular angina, and TTC), with poor prognosis. Adding these diseases to the classification of cardiomyopathies will facilitate diagnosis and preventive prolonged treatment, which should include intensive anti-stress therapy. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

  1. Towards quantum gravity via quantum field theory. Problems and perspectives

    Energy Technology Data Exchange (ETDEWEB)

    Fredenhagen, Klaus [II. Institut fuer Theoretische Physik, Universitaet Hamburg (Germany)

    2016-07-01

    General Relativity is a classical field theory; the standard methods for constructing a corresponding quantum field theory, however, meet severe difficulties, in particular perturbative non-renormalizability and the problem of background independence. Nevertheless, modern approaches to quantum field theory have significantly lowered these obstacles. On the side of non-renormalizability, this is the concept of effective theories, together with indications for better non-perturbative features of the renormalization group flow. On the side of background independence the main progress comes from an improved understanding of quantum field theories on generic curved spacetimes. Combining these informations, a promising approach to quantum gravity is an expansion around a classical solution which then is a quantum field theory on a given background, augmented by an identity which expresses independence against infinitesimal shifts of the background. The arising theory is expected to describe small corrections to classical general relativity. Inflationary cosmology is expected to arise as a lowest order approximation.

  2. A Large Cystic Variant of Gastro-intestinal Stromal Tumour arising from the Jejunum: A Case Report.

    Science.gov (United States)

    Shaikh, Salman Tehran; Upwanshi, Manish Harinarayan; Shetty, Tilakdas S; Ghetla, Smruti R; Gheewala, Hussain

    2015-04-01

    Gastrointestinal stromal tumours (GISTs) represent a mesenchymal neoplasm arising from the interstitial cells of cajal occurring mainly in the gastrointestinal tract. Here, we present a case of a large GIST arising from the jejunum with cystic presentation unlike the usual presentation as a solid mass. A 50-year-old male patient came with complaint of a painless mobile lump in abdomen of approximately 25 cm in size which had gradually increased over two years. Clinically mesenteric cyst was suspected. Intra-operatively the mass was a 30x25 cm cyst with approximately 2500 ml serous fluid present inside it arising from the anti-mesenteric border of the jejunum, adherent to the jejunum, appendix and the dome of the bladder. The fluid was aspirated and the mass excised along with resection of the involved jejunal segment and appendectomy was done. Diagnosis was confirmed on immunohistochemistry study. Imatinib Mesylate 400 mg OD was started as adjuvant therapy in view of the high risk of metastasis.

  3. On Wigner's problem, computability theory, and the definition of life

    International Nuclear Information System (INIS)

    Swain, J.

    1998-01-01

    In 1961, Eugene Wigner presented a clever argument that in a world which is adequately described by quantum mechanics, self-reproducing systems in general, and perhaps life in particular, would be incredibly improbable. The problem and some attempts at its solution are examined, and a new solution is presented based on computability theory. In particular, it is shown that computability theory provides limits on what can be known about a system in addition to those which arise from quantum mechanics. (author)

  4. Hierarchical Dobinski-type relations via substitution and the moment problem

    International Nuclear Information System (INIS)

    Penson, K A; Blasiak, P; Duchamp, G; Horzela, A; Solomon, A I

    2004-01-01

    We consider the transformation properties of integer sequences arising from the normal ordering of exponentiated boson ([a, a†] = 1) monomials of the form exp[λ(a†) r a], r = 1, 2, ..., under the composition of their exponential generating functions. They turn out to be of Sheffer type. We demonstrate that two key properties of these sequences remain preserved under substitutional composition: (a) the property of being the solution of the Stieltjes moment problem; and (b) the representation of these sequences through infinite series (Dobinski-type relations). We present a number of examples of such composition satisfying properties (a) and (b). We obtain new Dobinski-type formulae and solve the associated moment problem for several hierarchically defined combinatorial families of sequences

  5. Viable Solutions for seemingly Intractable Problems

    Directory of Open Access Journals (Sweden)

    Ashok Natarajan

    2015-10-01

    Full Text Available Life is filled with seemingly intractable problems. But life wisdom affirms that if there is a problem, there must be a solution. Or better yet, the solution to the problem lies within the problem itself. Problems have their roots in disharmony. Disharmony arises when a part separates itself from the whole and acts independently of the wider reality of which it is a part, as financial markets have separated themselves from the real economy and economy has detached itself from social and ecological consequences. Insistence on out-moded approaches under new conditions generates intractable problems, as when the framework of a heterogeneous nation-state is employed for the dominance of a single ethnic or religious group. Knowledge and culture are the supreme values of a society and core element of its capacity for accomplishment and development, yet both tend to be exclusively possessed by elites for their own benefit, rather than freely distributed to maximize their impact on society as a whole. Society evolves by the transformation of ignorance into knowledge. Life evolves by organization. The linking and integration of social organizations spur development. Mind itself is an organization and powerful force for development. Energy makes organization more efficient. Any problem can be solved by raising the effectiveness of energy by converting it into skill or capacity and transforming it into power through organization. What one person sees as a problem is an opportunity for another with wider vision. The difference in perception accounts for the difference in levels of accomplishment. So, those with the right perspective see opportunities where others see insolvable problems. Current problems are the result of irrationality, refusal to benefit from past experience and insistence on repeating past errors. Modern science, which was born to fight the superstition of religion, has become a source of superstition. Fully availing of the latest

  6. The Line-drawing Problem in Disease Definition.

    Science.gov (United States)

    Rogers, Wendy A; Walker, Mary Jean

    2017-08-01

    Biological dysfunction is regarded, in many accounts, as necessary and perhaps sufficient for disease. But although disease is conceptualized as all-or-nothing, biological functions often differ by degree. A tension is created by attempting to use a continuous variable as the basis for a categorical definition, raising questions about how we are to pinpoint the boundary between health and disease. This is the line-drawing problem. In this paper, we show how the line-drawing problem arises within "dysfunction-requiring" accounts of disease, such as those of Christopher Boorse and Jerome Wakefield. We then provide several detailed examples to establish that biological dysfunction cannot provide a boundary. We examine potential ways of resolving the line-drawing problem, either by dropping one of the claims that generates it, or by appealing to additional criteria. We argue that two of these options are plausible, and that each of these can be applied with regard to different diseases. © The Author 2017. Published by Oxford University Press, on behalf of the Journal of Medicine and Philosophy Inc. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  7. Analysis of an Automated Vehicle Routing Problem in Logistics considering Path Interruption

    Directory of Open Access Journals (Sweden)

    Yong Zhang

    2017-01-01

    Full Text Available The application of automated vehicles in logistics can efficiently reduce the cost of logistics and reduce the potential risks in the last mile. Considering the path restriction in the initial stage of the application of automated vehicles in logistics, the conventional model for a vehicle routing problem (VRP is modified. Thus, the automated vehicle routing problem with time windows (AVRPTW model considering path interruption is established. Additionally, an improved particle swarm optimisation (PSO algorithm is designed to solve this problem. Finally, a case study is undertaken to test the validity of the model and the algorithm. Four automated vehicles are designated to execute all delivery tasks required by 25 stores. Capacities of all of the automated vehicles are almost fully utilised. It is of considerable significance for the promotion of automated vehicles in last-mile situations to develop such research into real problems arising in the initial period.

  8. Conservation laws arising in the study of forward-forward Mean-Field Games

    KAUST Repository

    Gomes, Diogo A.; Nurbekyan, Levon; Sedjro, Marc

    2017-01-01

    We consider forward-forward Mean Field Game (MFG) models that arise in numerical approximations of stationary MFGs. First, we establish a link between these models and a class of hyperbolic conservation laws as well as certain nonlinear wave equations. Second, we investigate existence and long-time behavior of solutions for such models.

  9. Exploring Ethical Dilemmas for Principals Arising from Role Conflict with School Counsellors

    Science.gov (United States)

    Kimber, Megan; Campbell, Marilyn

    2014-01-01

    Acting in the best interests of students is central to the moral and ethical work of schools. Yet tensions can arise between principals and school counsellors as they work from at times opposing professional paradigms. In this article we report on principals' and counsellors' responses to scenarios covering confidentiality and the law,…

  10. Conservation laws arising in the study of forward-forward Mean-Field Games

    KAUST Repository

    Gomes, Diogo A.

    2017-04-24

    We consider forward-forward Mean Field Game (MFG) models that arise in numerical approximations of stationary MFGs. First, we establish a link between these models and a class of hyperbolic conservation laws as well as certain nonlinear wave equations. Second, we investigate existence and long-time behavior of solutions for such models.

  11. Solution of Constrained Optimal Control Problems Using Multiple Shooting and ESDIRK Methods

    DEFF Research Database (Denmark)

    Capolei, Andrea; Jørgensen, John Bagterp

    2012-01-01

    of this paper is the use of ESDIRK integration methods for solution of the initial value problems and the corresponding sensitivity equations arising in the multiple shooting algorithm. Compared to BDF-methods, ESDIRK-methods are advantageous in multiple shooting algorithms in which restarts and frequent...... algorithm. As we consider stiff systems, implicit solvers with sensitivity computation capabilities for initial value problems must be used in the multiple shooting algorithm. Traditionally, multi-step methods based on the BDF algorithm have been used for such problems. The main novel contribution...... discontinuities on each shooting interval are present. The ESDIRK methods are implemented using an inexact Newton method that reuses the factorization of the iteration matrix for the integration as well as the sensitivity computation. Numerical experiments are provided to demonstrate the algorithm....

  12. On the multiple depots vehicle routing problem with heterogeneous fleet capacity and velocity

    Science.gov (United States)

    Hanum, F.; Hartono, A. P.; Bakhtiar, T.

    2018-03-01

    This current manuscript concerns with the optimization problem arising in a route determination of products distribution. The problem is formulated in the form of multiple depots and time windowed vehicle routing problem with heterogeneous capacity and velocity of fleet. Model includes a number of constraints such as route continuity, multiple depots availability and serving time in addition to generic constraints. In dealing with the unique feature of heterogeneous velocity, we generate a number of velocity profiles along the road segments, which then converted into traveling-time tables. An illustrative example of rice distribution among villages by bureau of logistics is provided. Exact approach is utilized to determine the optimal solution in term of vehicle routes and starting time of service.

  13. Quick answers to quantitative problems a pocket primer

    CERN Document Server

    Page, G William

    1991-01-01

    No matter the field, professionals need to respond quickly to quantitative problems as they arise and to develop a quick understanding of what the data mean. Whether you are an aide to a city council member trying to decipher the true meaning of a citizen opinion poll, a private consultant to the health department estimating the number of pregnant teenagers in a neighborhood, or the executive director of a small agency striving to present your budget facts precisely and clearly, the techniques presented here are helpful to you and your work.Key Features* Presents relatively simple techniques t

  14. Intimacy Is a Transdiagnostic Problem for Cognitive Behavior Therapy: Functional Analytical Psychotherapy Is a Solution

    Science.gov (United States)

    Wetterneck, Chad T.; Hart, John M.

    2012-01-01

    Problems with intimacy and interpersonal issues are exhibited across most psychiatric disorders. However, most of the targets in Cognitive Behavioral Therapy are primarily intrapersonal in nature, with few directly involved in interpersonal functioning and effective intimacy. Functional Analytic Psychotherapy (FAP) provides a behavioral basis for…

  15. Arise--the Gentry are Coming!

    Science.gov (United States)

    McCaffrey, Patrick

    1982-01-01

    Gentrification, or the return of the middle class to renovated inner-city neighborhoods, is forcing out the aged and minority poor who can no longer afford the higher cost of housing in those areas. This has created the problem of a population of mostly Blacks and ethnic groups. (Author/MJL)

  16. Stabilizing inverse problems by internal data. II: non-local internal data and generic linearized uniqueness

    KAUST Repository

    Kuchment, Peter

    2015-05-10

    © 2015, Springer Basel. In the previous paper (Kuchment and Steinhauer in Inverse Probl 28(8):084007, 2012), the authors introduced a simple procedure that allows one to detect whether and explain why internal information arising in several novel coupled physics (hybrid) imaging modalities could turn extremely unstable techniques, such as optical tomography or electrical impedance tomography, into stable, good-resolution procedures. It was shown that in all cases of interest, the Fréchet derivative of the forward mapping is a pseudo-differential operator with an explicitly computable principal symbol. If one can set up the imaging procedure in such a way that the symbol is elliptic, this would indicate that the problem was stabilized. In the cases when the symbol is not elliptic, the technique suggests how to change the procedure (e.g., by adding extra measurements) to achieve ellipticity. In this article, we consider the situation arising in acousto-optical tomography (also called ultrasound modulated optical tomography), where the internal data available involves the Green’s function, and thus depends globally on the unknown parameter(s) of the equation and its solution. It is shown that the technique of (Kuchment and Steinhauer in Inverse Probl 28(8):084007, 2012) can be successfully adopted to this situation as well. A significant part of the article is devoted to results on generic uniqueness for the linearized problem in a variety of situations, including those arising in acousto-electric and quantitative photoacoustic tomography.

  17. Nodulocystic basal cell carcinoma arising directly from a seborrheic keratosis: A rare case report

    Directory of Open Access Journals (Sweden)

    Kana Shibao

    2016-01-01

    Full Text Available Seborrheic keratoses (SKs are common epidermal tumors composed of benign keratinocytes. Malignant skin tumors including basal cell carcinoma (BCC rarely arise within SKs. We report a rare case of an 82-year-old man with nodulocystic BCC that appeared at the center of a scaly hyperpigmented SK that had been presented for more than 10 years. It was histologically confirmed that CK19-positive BCC arose directly from the wall of the pseudohorn cyst, a part of the SK. Nodular and/or cystic BCC also rarely arise within SKs while the most common histologic type of BCC within SKs is the superficial type. Careful observation of SKs is important even though it is rarely a background condition for malignant transformation.

  18. The A-priori Traveling Salesman Problem with Time Windows

    DEFF Research Database (Denmark)

    Larsen, Allan; Madsen, Oli B.G.; Solomon, Marius M.

    2004-01-01

    seek to minimize lateness and examine the impact of this criterion choice on the distance traveled. Our focus on lateness is motivated by the problem faced by overnight mail service providers. We propose a real-time solution method that requires the vehicle, when idle, to wait at the current customer......In this paper we examine the traveling saleman problem with time windows for various degrees of dynamism. In contrast to the static problem, where the dispatcher can plan ahead, in the dynamic version, part or all of the necessary information becomes available only during the day of operation. We...... randomly generated data and on a real-world case study indicate that all policies proved capable of significantly reducing lateness. Our results also show that this can be accomplished with only small distance increases. The basic policy outperformed the other methods primarily when lateness and distance...

  19. Hyperspherical Coulomb spheroidal basis in the Coulomb three-body problem

    International Nuclear Information System (INIS)

    Abramov, D. I.

    2013-01-01

    A hyperspherical Coulomb spheroidal (HSCS) representation is proposed for the Coulomb three-body problem. This is a new expansion in the set of well-known Coulomb spheroidal functions. The orthogonality of Coulomb spheroidal functions on a constant-hyperradius surface ρ = const rather than on a constant-internuclear-distance surface R = const, as in the traditional Born-Oppenheimer approach, is a distinguishing feature of the proposed approach. Owing to this, the HSCS representation proves to be consistent with the asymptotic conditions for the scattering problem at energies below the threshold for three-body breakup: only a finite number of radial functions do not vanish in the limit of ρ→∞, with the result that the formulation of the scattering problem becomes substantially simpler. In the proposed approach, the HSCS basis functions are considerably simpler than those in the well-known adiabatic hyperspherical representation, which is also consistent with the asymptotic conditions. Specifically, the HSCS basis functions are completely factorized. Therefore, there arise no problems associated with avoided crossings of adiabatic hyperspherical terms.

  20. Boundary-value problems with integral conditions for a system of Lame equations in the space of almost periodic functions

    Directory of Open Access Journals (Sweden)

    Volodymyr S. Il'kiv

    2016-11-01

    Full Text Available We study a problem with integral boundary conditions in the time coordinate for a system of Lame equations of dynamic elasticity theory of an arbitrary dimension. We find necessary and sufficient conditions for the existence and uniqueness of solution in the class of almost periodic functions in the spatial variables. To solve the problem of small denominators arising while constructing solutions, we use the metric approach.

  1. A neural-network approach to the problem of photon-pair combinatorics

    International Nuclear Information System (INIS)

    Awes, T.C.

    1990-06-01

    A recursive neural-network algorithm is applied to the problem of correctly pairing photons from π 0 , η, and higher resonance decays in the presence of a large background of photons resulting from many simultaneous decays. The method uses the full information of the multi-photon final state to suppress the selection of false photon pairs which arise from the many combinatorial possibilities. The method is demonstrated for simulated photon events under semirealistic experimental conditions. 3 refs., 3 figs

  2. The fuel element of the first charge for EL 4; presentation, main problems arising in the research, production problems; L'element combustible du 1. jeu de EL 4; presentation, problemes essentiels poses par l'etude, problemes de fabrication

    Energy Technology Data Exchange (ETDEWEB)

    Ringot, C; Bailly, H; Bujas, R [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1964-07-01

    The fuel element making up the first charge for EL-4 is made of slightly enriched uranium oxide canned in stainless steel. This fuel element makes it possible to operate the reactor in the safest conditions awaiting the development of the fuel which will be finally adopted; this will have a low absorption can: beryllium, or a zirconium copper alloy. The 500 mm assembly is made up of 19 small rods placed on 3 rings, inside a graphite jacket. The solution adopted was a solution using completely independent small rods. This report deals with possible problems resulting from their study and production. (authors) [French] L'element combustible du 1er jeu EL-4 est un element combustible a oxyde d'uranium legerement enrichi gaine d'acier inoxydable. C'est un element combustible permettant de faire fonctionner le reacteur EL 4 dans des conditions aussi sures que possible avant de mettre au point le combustible definitif qui sera a gaine peu absorbante: beryllium, ou alliage zirconium-cuivre. L'assemblage de longueur 500 mm est constitue de 19 crayons places sur 3 couronnes, a l'interieur d'une chemise de graphite. La solution adoptee a ete une solution a crayons independants les uns des autres. Ce rapport traite des problemes eventuels poses par leur etude et leur fabrication. (auteurs)

  3. Word Problem Solving in Contemporary Math Education: A Plea for Reading Comprehension Skills Training

    Science.gov (United States)

    Boonen, Anton J. H.; de Koning, Björn B.; Jolles, Jelle; van der Schoot, Menno

    2016-01-01

    Successfully solving mathematical word problems requires both mental representation skills and reading comprehension skills. In Realistic Math Education (RME), however, students primarily learn to apply the first of these skills (i.e., representational skills) in the context of word problem solving. Given this, it seems legitimate to assume that students from a RME curriculum experience difficulties when asked to solve semantically complex word problems. We investigated this assumption under 80 sixth grade students who were classified as successful and less successful word problem solvers based on a standardized mathematics test. To this end, students completed word problems that ask for both mental representation skills and reading comprehension skills. The results showed that even successful word problem solvers had a low performance on semantically complex word problems, despite adequate performance on semantically less complex word problems. Based on this study, we concluded that reading comprehension skills should be given a (more) prominent role during word problem solving instruction in RME. PMID:26925012

  4. Word problem solving in contemporary math education: A plea for reading comprehension skills training

    Directory of Open Access Journals (Sweden)

    Anton eBoonen

    2016-02-01

    Full Text Available Successfully solving mathematical word problems requires both mental representation skills and reading comprehension skills. In Realistic Math Education (RME, however, students primarily learn to apply the first of these skills (i.e., representational skills in the context of word problem solving. Given this, it seems legitimate to assume that students from a RME curriculum experience difficulties when asked to solve semantically complex word problems. We investigated this assumption under 80 sixth grade students who were classified as successful and less successful word problem solvers based on a standardized mathematics test. To this end, students completed word problems that ask for both mental representation skills and reading comprehension skills. The results showed that even successful word problem solvers had a low performance on semantically complex word problems, despite adequate performance on semantically less complex word problems. Based on this study, we concluded that reading comprehension skills should be given a (more prominent role during word problem solving instruction in RME.

  5. Word Problem Solving in Contemporary Math Education: A Plea for Reading Comprehension Skills Training.

    Science.gov (United States)

    Boonen, Anton J H; de Koning, Björn B; Jolles, Jelle; van der Schoot, Menno

    2016-01-01

    Successfully solving mathematical word problems requires both mental representation skills and reading comprehension skills. In Realistic Math Education (RME), however, students primarily learn to apply the first of these skills (i.e., representational skills) in the context of word problem solving. Given this, it seems legitimate to assume that students from a RME curriculum experience difficulties when asked to solve semantically complex word problems. We investigated this assumption under 80 sixth grade students who were classified as successful and less successful word problem solvers based on a standardized mathematics test. To this end, students completed word problems that ask for both mental representation skills and reading comprehension skills. The results showed that even successful word problem solvers had a low performance on semantically complex word problems, despite adequate performance on semantically less complex word problems. Based on this study, we concluded that reading comprehension skills should be given a (more) prominent role during word problem solving instruction in RME.

  6. DOUBLE TRIALS METHOD FOR NONLINEAR PROBLEMS ARISING IN HEAT TRANSFER

    Directory of Open Access Journals (Sweden)

    Chun-Hui He

    2011-01-01

    Full Text Available According to an ancient Chinese algorithm, the Ying Buzu Shu, in about second century BC, known as the rule of double false position in West after 1202 AD, two trial roots are assumed to solve algebraic equations. The solution procedure can be extended to solve nonlinear differential equations by constructing an approximate solution with an unknown parameter, and the unknown parameter can be easily determined using the Ying Buzu Shu. An example in heat transfer is given to elucidate the solution procedure.

  7. Scalable Domain Decomposition Preconditioners for Heterogeneous Elliptic Problems

    Directory of Open Access Journals (Sweden)

    Pierre Jolivet

    2014-01-01

    Full Text Available Domain decomposition methods are, alongside multigrid methods, one of the dominant paradigms in contemporary large-scale partial differential equation simulation. In this paper, a lightweight implementation of a theoretically and numerically scalable preconditioner is presented in the context of overlapping methods. The performance of this work is assessed by numerical simulations executed on thousands of cores, for solving various highly heterogeneous elliptic problems in both 2D and 3D with billions of degrees of freedom. Such problems arise in computational science and engineering, in solid and fluid mechanics. While focusing on overlapping domain decomposition methods might seem too restrictive, it will be shown how this work can be applied to a variety of other methods, such as non-overlapping methods and abstract deflation based preconditioners. It is also presented how multilevel preconditioners can be used to avoid communication during an iterative process such as a Krylov method.

  8. Toward an Improved Representation of Middle Atmospheric Dynamics Thanks to the ARISE Project

    Science.gov (United States)

    Blanc, E.; Ceranna, L.; Hauchecorne, A.; Charlton-Perez, A.; Marchetti, E.; Evers, L. G.; Kvaerna, T.; Lastovicka, J.; Eliasson, L.; Crosby, N. B.; Blanc-Benon, P.; Le Pichon, A.; Brachet, N.; Pilger, C.; Keckhut, P.; Assink, J. D.; Smets, P. S. M.; Lee, C. F.; Kero, J.; Sindelarova, T.; Kämpfer, N.; Rüfenacht, R.; Farges, T.; Millet, C.; Näsholm, S. P.; Gibbons, S. J.; Espy, P. J.; Hibbins, R. E.; Heinrich, P.; Ripepe, M.; Khaykin, S.; Mze, N.; Chum, J.

    2018-03-01

    This paper reviews recent progress toward understanding the dynamics of the middle atmosphere in the framework of the Atmospheric Dynamics Research InfraStructure in Europe (ARISE) initiative. The middle atmosphere, integrating the stratosphere and mesosphere, is a crucial region which influences tropospheric weather and climate. Enhancing the understanding of middle atmosphere dynamics requires improved measurement of the propagation and breaking of planetary and gravity waves originating in the lowest levels of the atmosphere. Inter-comparison studies have shown large discrepancies between observations and models, especially during unresolved disturbances such as sudden stratospheric warmings for which model accuracy is poorer due to a lack of observational constraints. Correctly predicting the variability of the middle atmosphere can lead to improvements in tropospheric weather forecasts on timescales of weeks to season. The ARISE project integrates different station networks providing observations from ground to the lower thermosphere, including the infrasound system developed for the Comprehensive Nuclear-Test-Ban Treaty verification, the Lidar Network for the Detection of Atmospheric Composition Change, complementary meteor radars, wind radiometers, ionospheric sounders and satellites. This paper presents several examples which show how multi-instrument observations can provide a better description of the vertical dynamics structure of the middle atmosphere, especially during large disturbances such as gravity waves activity and stratospheric warming events. The paper then demonstrates the interest of ARISE data in data assimilation for weather forecasting and re-analyzes the determination of dynamics evolution with climate change and the monitoring of atmospheric extreme events which have an atmospheric signature, such as thunderstorms or volcanic eruptions.

  9. Learning to Solve Addition and Subtraction Word Problems in English as an Imported Language

    Science.gov (United States)

    Verzosa, Debbie Bautista; Mulligan, Joanne

    2013-01-01

    This paper reports an intervention phase of a design study aimed to assist second-grade Filipino children in solving addition word problems in English, a language they primarily encounter only in school. With Filipino as the medium of instruction, an out-of-school pedagogical intervention providing linguistic and representational scaffolds was…

  10. Conjunctival amelanotic malignant melanoma arising in primary acquired melanosis sine pigmento.

    Science.gov (United States)

    Jay, V; Font, R L

    1998-01-01

    The authors describe an amelanotic malignant melanoma of the conjunctiva in association with primary acquired melanosis (PAM) sine pigmento, and highlight the clinical and pathologic features of this rare entity. Histopathologic and immunohistochemical studies were performed on a conjunctival tumor in a 54-year-old white woman. Case report. Histopathologic examination revealed an invasive amelanotic melanoma of the conjunctiva, with anterior orbital extension arising from intraepithelial dysplastic melanocytes that lacked melanin pigment (PAM sine pigmento). Both the malignant melanoma cells and the intraepithelial dysplastic melanocytes in the areas of PAM exhibited S-100 and HMB-45 positivity. The patient underwent an orbital exenteration that disclosed tumor within the anterior orbit inferiorly. Amelanotic invasive malignant melanoma can arise in association with PAM sine pigmento, as seen in our patient who had orbital invasion necessitating exenteration. This aggressive form of conjunctival melanoma is often associated with a poor prognosis and risk of metastatic disease. Absence of conjunctival pigmentation in PAM sine pigmento prevents early clinical detection of this variant of PAM. This lack of pigmentation also makes clinical diagnosis virtually impossible, and diagnosis can only be established histopathologically. Awareness of this nonpigmented variety of PAM is crucial for early recognition and appropriate management of the associated melanoma.

  11. Trends for minimization of radioactive waste arising from spent nuclear fuel reprocessing

    International Nuclear Information System (INIS)

    Polyakov, A.S.; Koltunov, V.S.; Marchenko, V.I.; Ilozhev, A.P.; Mukhin, I.V.

    2000-01-01

    Research and development of technologies for radioactive waste (RAW) minimization arising from spent nuclear fuel reprocessing are discussed. Novel reductants of Pu and Np ions, reagents of purification recycled extractant, possibility of the electrochemical methods are studied. The partitioning of high activity level waste are considered. Examples of microbiological methods decomposition of radioactive waste presented. (authors)

  12. Chemodectomas arising in temporal bone structures

    International Nuclear Information System (INIS)

    Dickens, W.J.; Million, R.R.; Cassisi, N.J.; Singleton, G.T.

    1982-01-01

    Eighteen patients with chemodectomas arising in temporal bone structures were evaluated and treated at the University of Florida. Seventeen patients have each been followed a minimum of 3 years. Patients were retrospectively staged as having ''local'' or ''advanced'' disease, depending on the presence or absence of bone destruction and/or cranial nerve involvement. Fourteen of the patients received radiation therapy as all or part of their therapy; 6 patients were treated with radiation therapy alone, 3 patients were irradiated immediately postoperatively for residual disease, and 5 patients had radiation therapy for recurrence after operation. They were treated with cobalt-60 radiation with doses ranging from 3760 to 5640 rad. All irradiated patients demonstrated evidence of tumor regression, and none have had tumor recurrence with followup of 3-12 years. Of the 8 patients with cranial nerve paralysis prior to therapy, 5 had return of function of 1 or more cranial nerves. One of 6 patients treated initially with radiation therapy had a complication, while 6 of 8 patients irradiated postoperatively had complications. None of the complications were fatal. Three patients treated by operation for early disease limited to the hypotympanum had the disease controlled for 11-12 years. Guidelines for the selection of initial therapy are discussed

  13. Nuclear regulatory challenges arising from competition in electricity markets

    International Nuclear Information System (INIS)

    2001-01-01

    In recent years a world-wide trend has been developing to introduce competition in electricity markets. As market competition unfolds, it produces a wide range of safety challenges for nuclear power plant operators and regulators. Nuclear regulators must be aware of the potential safety challenges produced and consider whether new regulatory response strategies are warranted. This report describes many of these challenges, their implications and possible regulatory response strategies. The intended audience is primarily nuclear safety regulators, although government authorities, nuclear power plant operators and the general public may also be interested. (author)

  14. 'Health should not have to be a problem': talking health and accountability in an internet forum on veganism.

    Science.gov (United States)

    Sneijder, Petra; te Molder, Hedwig F M

    2004-07-01

    This article draws upon insights from discursive psychology to examine how participants in an Internet forum on veganism orient to the relationship between food choice, health and accountability. First, we explore the ways in which participants ascribe responsibility for health problems like vitamin deficiency to individual recipients. By suggesting individual practices as a cause for problems, speakers undermine the notion that problems arise through veganism as a matter of principle. Second, we show how participants construct solutions to individual health problems as involving mundane and simple actions. Both discursive procedures enable speakers to resist negative assumptions about the potentially complicated nature of veganism in relation to health protection.

  15. Triacylglycerol Accumulation is not primarily affected in Myotubes established from Type 2 Diabetic Subjects

    DEFF Research Database (Denmark)

    Gaster, Michael; Beck-Nielsen, Henning

    2006-01-01

    In the present study, we investigated triacylglycerol (TAG) accumulation, glucose and fatty acid (FA) uptake, and glycogen synthesis (GS) in human myotubes from healthy, lean, and obese subjects with and without type 2 diabetes (T2D), exposed to increasing palmitate (PA) and oleate (OA...... uptake (P0.05). These results indicate that (1) TAG accumulation is not primarily affected in skeletal muscle tissue of obese and T2D; (2) induced inhibition of oxidative phosphorylation is followed by TAG accumulation...... in skeletal muscle of obese and T2D subjects is adaptive....

  16. Digital holographic reconstruction detection of localized corrosion arising from scratches

    Directory of Open Access Journals (Sweden)

    LIANG WANG

    2010-04-01

    Full Text Available In this study, electrochemical methods and the digital holographic reconstruction technique were combined to detect the localized scratch-induced corrosion process of Alloy 690 in 0.50 mol dm-3 H2SO4 containing 0.10 mol dm-3 NaCl. The numerical reconstruction method has been proved to be an effective technique to detect changes of solution concentration. One can obtain direct information from the reconstructed images and capture subtle more revealing changes. It provides a method to detect localized corrosion arising from scratches.

  17. Lifelong learning for musicians: critical issues arising from a case study of Connect

    NARCIS (Netherlands)

    Renshaw, Peter

    2005-01-01

    This article intends to focus on those critical issues arising from the Connect case study (Renshaw, 2005) that have wider applicability in contemporary professional practice in terms of lifelong learning. Special attention will be given to the following areas: • formal, non-formal and informal

  18. Employee problems and their consequences in the technology industry: evidence from surveys and counseling records.

    Science.gov (United States)

    Wang, Ching-Wen; Lin, Po-Chang; Sha, Chyuan

    2014-06-01

    To support employees' work and health, organizations should help employees cope with common problems. Previous studies have focused primarily on work-related problems across multiple industries rather than on evaluating industry-specific issues. Here, two approaches identified common work and non-work employee problems in the technology industry with the strongest correlations with psychosomatic health and life satisfaction. Study 1 used questionnaires to identify the problems that were perceived as the most frequent by lower-level employees (N = 355) working in the technology industry. Study 2 evaluated employees' coping behaviors by analyzing (with permission) counseling records collected from an employee assistance service company (N = 276). Employees reported a variety of problems; work problems were the only problems (of the top 5 problems) reported in both studies. Several problems emerged in the counseling records (e.g., legal issues, career development, family and marriage problems, and emotional problems) but not in the surveys. Future research should apply these observations to develop scales for measuring employee stressors.

  19. Exact and heuristic solution approaches for the Integrated Job Scheduling and Constrained Network Routing Problem

    DEFF Research Database (Denmark)

    Gamst, M.

    2014-01-01

    problem. The methods are computationally evaluated on test instances arising from telecommunications with up to 500 jobs and 500 machines. Results show that solving the integrated job scheduling and constrained network routing problem to optimality is very difficult. The exact solution approach performs......This paper examines the problem of scheduling a number of jobs on a finite set of machines such that the overall profit of executed jobs is maximized. Each job has a certain demand, which must be sent to the executing machine via constrained paths. A job cannot start before all its demands have...... arrived at the machine. Furthermore, two resource demand transmissions cannot use the same edge in the same time period. The problem has application in grid computing, where a number of geographically distributed machines work together for solving large problems. The machines are connected through...

  20. Primary intraosseous squamous cell carcinoma of the mandible arising de novo.

    Science.gov (United States)

    Shamim, Thorakkal

    2009-07-01

    Primary intraosseous squamous cell carcinoma is an odontogenic tumour with aggressive behaviour usually noticed in 6th to 7th decades of life. The tumour is characterized by progressive swelling of the jaw, pain and loosening of teeth. Microscopically, the lesion is showing foci of keratinising cells separated by collagenous connective tissue stroma. A case of primary intraosseous squamous cell carcinoma of mandible arising de novo in a 40-year-old man is reported.