A STUDY OF THE LEADERSHIP BEHAVIORS REPORTED BY PRINCIPALS AND OBSERVED BY TEACHERS AND ITS RELATION WITH PRINCIPALS’ MANAGEMENT EXPERIENCE

Directory of Open Access Journals (Sweden)

Zaid Sardarzahi, Zaid

2015-06-01

Full Text Available The present paper aims to study the leadership behaviors reported by principals and observed by teachers and its relationship with management experience of principals. A quantitative method used in this study. Target population included all principals and teachers of guidance schools and high schools in Dashtiari District, Iran. A sample consisted of 46 principals and 129 teachers were selected by stratified sampling and simple random sampling methods. Leadership Behavior Description Questionnaire (LBDQ developed by Kozes and Posner (2001 was used for data collection. The obtained data were analyzed using one sample and independent t-test, correlation coefficient and pearson chi-square test. The results showed that teachers describe the leadership behaviors of their principals relatively good. However, the principals themselves evaluated their leadership behaviors as very good. In comparison between leadership behaviors self-reported by principals and those observed by teachers, it was found that there is a significant difference between the views and evaluations of teachers and principals on all components of leadership behaviors of principals, except empowerment. In fact, principals have described their leadership behaviors at a better and more appropriate level than what teachers have done. From the perspective of both teachers and principals, there is no significant relationship between none of the components of leadership behaviors and management experience of principals.

Generalized synthetic aperture radar automatic target recognition by convolutional neural network with joint use of two-dimensional principal component analysis and support vector machine

Science.gov (United States)

Zheng, Ce; Jiang, Xue; Liu, Xingzhao

2017-10-01

Convolutional neural network (CNN), as a vital part of the deep learning research field, has shown powerful potential for automatic target recognition (ATR) of synthetic aperture radar (SAR). However, the high complexity caused by the deep structure of CNN makes it difficult to generalize. An improved form of CNN with higher generalization capability and less probability of overfitting, which further improves the efficiency and robustness of the SAR ATR system, is proposed. The convolution layers of CNN are combined with a two-dimensional principal component analysis algorithm. Correspondingly, the kernel support vector machine is utilized as the classifier layer instead of the multilayer perceptron. The verification experiments are implemented using the moving and stationary target acquisition and recognition database, and the results validate the efficiency of the proposed method.

Transforming Nigerian Youth Leadership Capacities in Secondary Schools through Principals' Managerial Role Effectiveness

Science.gov (United States)

Edet, Aniefiok Oswald; Ekpoh, Uduak Imo; Uko, Esther Samuel

2015-01-01

The study examined principals' management role effectiveness of secondary schools for youth leadership in Calabar Education Zone of Cross River State. The study employed survey research design. The target population comprised all 158 principals in both public and private secondary schools in the study area. The sample selected through random…

TAPIR, a web server for the prediction of plant microRNA targets, including target mimics.

Science.gov (United States)

Bonnet, Eric; He, Ying; Billiau, Kenny; Van de Peer, Yves

2010-06-15

We present a new web server called TAPIR, designed for the prediction of plant microRNA targets. The server offers the possibility to search for plant miRNA targets using a fast and a precise algorithm. The precise option is much slower but guarantees to find less perfectly paired miRNA-target duplexes. Furthermore, the precise option allows the prediction of target mimics, which are characterized by a miRNA-target duplex having a large loop, making them undetectable by traditional tools. The TAPIR web server can be accessed at: http://bioinformatics.psb.ugent.be/webtools/tapir. Supplementary data are available at Bioinformatics online.

An Assessment of the Perceived Instructional Leadership Behaviors of Assistant Principals

Science.gov (United States)

Atkinson, Ronald E., Jr.

2013-01-01

This study examined the extent to which the role of the assistant principal is perceived to include instructional leadership behaviors. Specifically, this study compared the perceptions of instructional leadership practices of elementary, middle, and high school assistant principals from the perspectives of assistant principals, principals, and…

Female Traditional Principals and Co-Principals: Experiences of Role Conflict and Job Satisfaction

Science.gov (United States)

Eckman, Ellen Wexler; Kelber, Sheryl Talcott

2010-01-01

This paper presents a secondary analysis of survey data focusing on role conflict and job satisfaction of 102 female principals. Data were collected from 51 female traditional principals and 51 female co-principals. By examining the traditional and co-principal leadership models as experienced by female principals, this paper addresses the impact…

"Mujeres" in the Principal's Office: Latina School Leaders

Science.gov (United States)

Méndez-Morse, Sylvia; Murakami, Elizabeth T.; Byrne-Jiménez, Mónica; Hernandez, Frank

2015-01-01

This article is based on a national survey of Latina/o principals and assistant principals conducted by the National Latina/o Leadership Project and focuses on the women participants. Included is a description of Latinas' leadership experiences, their career paths, and the influence of racial/ethnic identity on their leadership practice. The…

The Effect of Principals' Technological Leadership on Teachers' Technological Literacy and Teaching Effectiveness in Taiwanese Elementary Schools

Science.gov (United States)

Chang, I-Hua

2012-01-01

The purpose of this study is to investigate the relationships among principals' technological leadership, teachers' technological literacy, and teaching effectiveness. The survey target population consists of 1,000 teachers randomly selected from Taiwanese elementary schools. The survey asked teachers to measure the effectiveness of principals'…

Lessons from Principal-Agent Theory for Public Expenditure Management in Pacific Island Countries

OpenAIRE

Paul, Elisabeth

2006-01-01

The paper discusses how the principal-agent theory of economics may provide a suitable analytical framework and interesting lessons for the targeting of public expenditure management reforms in Pacific island economies Peer reviewed

A Multi-task Principal Agent Model for Knowledge Contribution of Enterprise Staff

Directory of Open Access Journals (Sweden)

Chengyi LE

2016-10-01

Full Text Available According to the different behavior characteristics of knowledge contribution of enterprise employees, a multi-task principal-agent relationship of knowledge contribution between enterprise and employees is established based on principal-agent theory, analyzing staff’s knowledge contribution behavior of knowledge creation and knowledge participation. Based on this, a multi-task principal agent model for knowledge contribution of enterprise staff is developed to formulate the asymmetry of information in knowledge contribution Then, a set of incentive measures are derived from the theoretic model, aiming to prompt the knowledge contribution in enterprise. The result shows that staff’s knowledge creation behavior and positive participation behavior can influence and further promote each other Enterprise should set up respective target levels of both knowledge creation contribution and knowledge participation contribution and make them irreplaceable to each other. This work contributes primarily to the development of the literature on knowledge management and principal-agent theory. In addition, the applicability of the findings will be improved by further empirical analysis.

Principals, Trust, and Cultivating Vibrant Schools

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Megan Tschannen-Moran

2015-03-01

Full Text Available Although principals are ultimately held accountable to student learning in their buildings, the most consistent research results have suggested that their impact on student achievement is largely indirect. Leithwood, Patten, and Jantzi proposed four paths through which this indirect influence would flow, and the purpose of this special issue is to examine in greater depth these mediating variables. Among mediating variables, we assert that trust is key. In this paper, we explore the evidence that points to the role that faculty trust in the principal plays in student learning and how principals can cultivate trust by attending to the five facets of trust, as well as the correlates of trust that mediate student learning, including academic press, collective teacher efficacy, and teacher professionalism. We argue that trust plays a role in each of the four paths identified by Leithwood, Patten, and Jantzi. Finally, we explore possible new directions for future research.

29 CFR 1471.995 - Principal.

Science.gov (United States)

2010-07-01

... SUSPENSION (NONPROCUREMENT) Definitions § 1471.995 Principal. Principal means— (a) An officer, director, owner, partner, principal investigator, or other person within a participant with management or... 29 Labor 4 2010-07-01 2010-07-01 false Principal. 1471.995 Section 1471.995 Labor Regulations...

Portraits of Principal Practice: Time Allocation and School Principal Work

Science.gov (United States)

Sebastian, James; Camburn, Eric M.; Spillane, James P.

2018-01-01

Purpose: The purpose of this study was to examine how school principals in urban settings distributed their time working on critical school functions. We also examined who principals worked with and how their time allocation patterns varied by school contextual characteristics. Research Method/Approach: The study was conducted in an urban school…

Identifying and Addressing Themes of Job Dissatisfaction for Secondary Principals

Science.gov (United States)

De Jong, David; Grundmeyer, Trent; Yankey, Julie

2017-01-01

Secondary principals serve in important roles that are complex, high-stress, and include demanding job responsibilities. Key stakeholders such as superintendents, school board members, and legislators must understand the challenges facing secondary principals in order to address the current themes of job dissatisfaction. Using new survey data…

31 CFR 19.995 - Principal.

Science.gov (United States)

2010-07-01

... SUSPENSION (NONPROCUREMENT) Definitions § 19.995 Principal. Principal means— (a) An officer, director, owner, partner, principal investigator, or other person within a participant with management or supervisory... 31 Money and Finance: Treasury 1 2010-07-01 2010-07-01 false Principal. 19.995 Section 19.995...

22 CFR 208.995 - Principal.

Science.gov (United States)

2010-04-01

... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Principal. 208.995 Section 208.995 Foreign...) Definitions § 208.995 Principal. Principal means— (a) An officer, director, owner, partner, principal investigator, or other person within a participant with management or supervisory responsibilities related to a...

22 CFR 1006.995 - Principal.

Science.gov (United States)

2010-04-01

... 22 Foreign Relations 2 2010-04-01 2010-04-01 true Principal. 1006.995 Section 1006.995 Foreign... § 1006.995 Principal. Principal means— (a) An officer, director, owner, partner, principal investigator, or other person within a participant with management or supervisory responsibilities related to a...

2 CFR 180.995 - Principal.

Science.gov (United States)

2010-01-01

... 2 Grants and Agreements 1 2010-01-01 2010-01-01 false Principal. 180.995 Section 180.995 Grants and Agreements OFFICE OF MANAGEMENT AND BUDGET GOVERNMENTWIDE GUIDANCE FOR GRANTS AND AGREEMENTS... § 180.995 Principal. Principal means— (a) An officer, director, owner, partner, principal investigator...

22 CFR 1508.995 - Principal.

Science.gov (United States)

2010-04-01

... 22 Foreign Relations 2 2010-04-01 2010-04-01 true Principal. 1508.995 Section 1508.995 Foreign...) Definitions § 1508.995 Principal. Principal means— (a) An officer, director, owner, partner, principal investigator, or other person within a participant with management or supervisory responsibilities related to a...

The Principal and Tort Liability.

Science.gov (United States)

Stern, Ralph D.

The emphasis of this chapter is on the tort liability of principals, especially their commission of unintentional torts or torts resulting from negligent conduct. A tort is defined as a wrongful act, not including a breach of contract or trust, which results in injury to another's person, property, or reputation and for which the injured party is…

Principal stratification in causal inference.

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Frangakis, Constantine E; Rubin, Donald B

2002-03-01

Many scientific problems require that treatment comparisons be adjusted for posttreatment variables, but the estimands underlying standard methods are not causal effects. To address this deficiency, we propose a general framework for comparing treatments adjusting for posttreatment variables that yields principal effects based on principal stratification. Principal stratification with respect to a posttreatment variable is a cross-classification of subjects defined by the joint potential values of that posttreatment variable tinder each of the treatments being compared. Principal effects are causal effects within a principal stratum. The key property of principal strata is that they are not affected by treatment assignment and therefore can be used just as any pretreatment covariate. such as age category. As a result, the central property of our principal effects is that they are always causal effects and do not suffer from the complications of standard posttreatment-adjusted estimands. We discuss briefly that such principal causal effects are the link between three recent applications with adjustment for posttreatment variables: (i) treatment noncompliance, (ii) missing outcomes (dropout) following treatment noncompliance. and (iii) censoring by death. We then attack the problem of surrogate or biomarker endpoints, where we show, using principal causal effects, that all current definitions of surrogacy, even when perfectly true, do not generally have the desired interpretation as causal effects of treatment on outcome. We go on to forrmulate estimands based on principal stratification and principal causal effects and show their superiority.

Principals' Salaries, 2007-2008

Science.gov (United States)

Cooke, Willa D.; Licciardi, Chris

2008-01-01

How do salaries of elementary and middle school principals compare with those of other administrators and classroom teachers? Are increases in salaries of principals keeping pace with increases in salaries of classroom teachers? And how have principals' salaries fared over the years when the cost of living is taken into account? There are reliable…

21 CFR 1404.995 - Principal.

Science.gov (United States)

2010-04-01

... 21 Food and Drugs 9 2010-04-01 2010-04-01 false Principal. 1404.995 Section 1404.995 Food and...) Definitions § 1404.995 Principal. Principal means— (a) An officer, director, owner, partner, principal investigator, or other person within a participant with management or supervisory responsibilities related to a...

34 CFR 85.995 - Principal.

Science.gov (United States)

2010-07-01

... 34 Education 1 2010-07-01 2010-07-01 false Principal. 85.995 Section 85.995 Education Office of...) Definitions § 85.995 Principal. Principal means— (a) An officer, director, owner, partner, principal investigator, or other person within a participant with management or supervisory responsibilities related to a...

A Principal's Guide to Children's Allergies.

Science.gov (United States)

Munoz-Furlong, Anne

1999-01-01

Discusses several common children's allergies, including allergic rhinitis, asthma, atopic dermatitis, food allergies, and anaphylactic shock. Principals should become familiar with various medications and should work with children's parents and physicians to determine how to manage their allergies at school. Allergen avoidance is the best…

Principal Self-Efficacy and Work Engagement: Assessing a Norwegian Principal Self-Efficacy Scale

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Federici, Roger A.; Skaalvik, Einar M.

2011-01-01

One purpose of the present study was to develop and test the factor structure of a multidimensional and hierarchical Norwegian Principal Self-Efficacy Scale (NPSES). Another purpose of the study was to investigate the relationship between principal self-efficacy and work engagement. Principal self-efficacy was measured by the 22-item NPSES. Work…

Principal succession: The socialisation of a primary school principal in South Africa

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Gertruida M. Steyn

2013-04-01

Full Text Available This study focussed on the socialisation of a new principal in a South African primary school with a strong Christian culture. He was appointed when the predecessor retired after more than two decades. The conceptual framework focuses on the three phases of socialisation: professional socialisation, organisational socialisation and occupational identity, which are used to interpret the study. A qualitative study, which occurred during two phases, investigated the phenomenon, principal succession, in the particular school. The data collection methods included a number of interviews with the principal, a focus group interview with staff members who experienced the previous principal’s leadership practice, and individual interviews with staff members. The following categories emerged from the data analysis: Recalling the previous principal: ‘One sees Mr X [the predecessor] everywhere’; Entry and orientation: ‘I found it intimidating initially’; and Immersion and reshaping: ‘Reins that previously were a bit slack, he is now pulling tight’.Die sosialisering van ’n primêre skoolhoof in Suid-Afrika. Hierdie studie het gefokus op die sosialisering van ’n nuwe skoolhoof in ’n Suid-Afrikaanse primêre skool met ’n sterk Christelike kultuur. Hy is aangestel toe sy voorganger ná meer as twee dekades afgetree het. Die konseptuele raamwerk, wat gebruik is om die bevindinge te interpreteer, het op die drie fases van sosialisering gefokus, naamlik professionele sosialisering, organisatoriese sosialisering en beroepsidentiteit. ’n Kwalitatiewe ondersoek na die skoolhoofopvolgingverskynsel in die bepaalde skool is in twee fases gedoen. Die data-insamelingsmetodes het ’n aantal onderhoude met die skoolhoof, ’n fokusgroeponderhoud met personeellede wat ook onder leierskap van die vorige skoolhoof gewerk het en individuele onderhoude met personeellede ingesluit. Tydens die data-analise het die volgende kategorieë na vore gekom

Teacher and Principal Perceptions of How Principal Transformational and Instructional Leadership Behaviors Relate to Student Achievement

Science.gov (United States)

Steele, Gayle

2012-01-01

Because of public concern over the effectiveness of our schools, a new evaluation system was put in place to hold principals and teachers directly accountable for student academic achievement. Part of this evaluation included student performance on state assessments. The purpose of this qualitative study sought to examine how the transformation…

School Principals in Southern Thailand: Exploring Trust with Community Leaders during Conflict

Science.gov (United States)

Brooks, Melanie C.

2015-01-01

This article reports findings from a case study of school principals in Southern Thailand who work in areas targeted by Muslim separatist groups. Data were gathered and analyzed using a conceptual framework that conceived of trust as five interrelated constructs: benevolence, honesty, openness, reliability, and competence. This study builds on…

An Investigation of Teacher, Principal, and Superintendent Perceptions on the Ability of the National Framework for Principal Evaluations to Measure Principals' Leadership Competencies

Science.gov (United States)

Lamb, Lori D.

2014-01-01

The purpose of this qualitative study was to investigate the perceptions of effective principals' leadership competencies; determine if the perceptions of teachers, principals, and superintendents aligned with the proposed National Framework for Principal Evaluations initiative. This study examined the six domains of leadership outlined by the…

Are Teacher and Principal Candidates Prepared to Address Student Cyberbullying?

Science.gov (United States)

Styron, Ronald A., Jr.; Bonner, Jessica L.; Styron, Jennifer L.; Bridgeforth, James; Martin, Cecelia

2016-01-01

The purpose of this study was to examine the preparation of teacher and principal candidates to address problems created in K-12 settings as a result of cyberbullying. Participants included teacher and principal preparation students. Findings indicated that respondents were familiar with the most common forms of cyberbullying and its impact on…

Fabrication of cryogenic inertial-confinement-fusion targets using target free-fall technique. Report No. 2-82

International Nuclear Information System (INIS)

Kim, K.; Murphy, M.J.

1982-04-01

Techniques for fabricating cryogenic inertial confinement fusion targets (i.e., spherical shells containing a uniform layer of DT ice) are investigated using target free-fall concept. Detection and characterization of the moving targets are effected by optoelectronic means, of which the principal is an RF ac-interferometer. This interferometer system demonstrates, for the first time, the speed capabilities of the phase-modulation ac-interferometry. New techiques developed for handling, holding, launching, and transporting targets are also described. Results obtained at both room and cryogenic temperatures are presented

Emerging Technology Trends and Ethical Practices for the School Principal

Science.gov (United States)

Garland, Virginia E.

2010-01-01

What is the school principal's role in ensuring ethical technology use while promoting the use of wireless and advanced technologies in instruction? The rapid advances in technology in only the past 5 years, including the increase in laptops and smart phones, have transformed both educational practices and the role of the school principal as…

Generation of Modified Pestiviruses by Targeted Recombination

DEFF Research Database (Denmark)

Rasmussen, Thomas Bruun; Friis, Martin Barfred; Risager, Peter Christian

involves targeted modification of viral cDNA genomes, cloned within BACs, by Red/ET recombination-mediated mutagenesis in E.coli DH10B cells. Using recombination-mediated mutagenesis for the targeted design, the work can be expedited and focused in principal on any sequence within the viral genome...

School Principals as Marketing Managers: The Expanding Role of Marketing for School Development

Science.gov (United States)

Anast-May, Linda; Mitchell, Mark; Buckner, Barbara Chesler; Elsberry, Cindy

2012-01-01

This study examined the relative importance that school principals attach to aspects of their role as marketing managers for their schools and their relative satisfaction with their efforts to date. The study included 60 principals from two school districts. Findings suggest that principals are aware of the importance of marketing in today's…

RE Rooted in Principal's Biography

NARCIS (Netherlands)

ter Avest, Ina; Bakker, C.

2017-01-01

Critical incidents in the biography of principals appear to be steering in their innovative way of constructing InterReligious Education in their schools. In this contribution, the authors present the biographical narratives of 4 principals: 1 principal introducing interreligious education in a

Targeting BRCAness in Gastric Cancer

Science.gov (United States)

2017-10-01

Award Number: W81XWH-16-1-0470 TITLE: Targeting BRCAness in Gastric Cancer PRINCIPAL INVESTIGATOR: Yelena Janjigian CONTRACTING ORGANIZATION...Sloan-Kettering Institute for Cancer Research New York, NY 10065 REPORT DATE: October 2017 TYPE OF REPORT: Annual PREPARED FOR: U.S. Army Medical...Targeting BRCAness in Gastric Cancer 5b. GRANT NUMBER W81XWH-16-1-0473 (Ashworth) 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) Eric Collisson, David

Targeting BRCAness in Gastric Cancer

Science.gov (United States)

2017-10-01

Award Number: W81XWH-16-1-0472 TITLE: Targeting BRCAness in Gastric Cancer PRINCIPAL INVESTIGATOR: Lawrence Fong CONTRACTING ORGANIZATION...Targeting BRCAness in Gastric Cancer 5b. GRANT NUMBER W81XWH-16-1-0473 (Ashworth) 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) Eric Collisson, David Quigley...for Public Release; Distribution Unlimited 13. SUPPLEMENTARY NOTES 14. ABSTRACT We performed the screen of gastric cancer cell lines for their

Assessing the Relationship of Principals' Leadership Styles on Teacher Satisfaction and Teacher Turnover

Science.gov (United States)

Hamilton, Ericka

2016-01-01

Effective and efficient leadership helps schools to achieve established targets and ensures that they are operating according to federal and state guidelines. This quantitative comparative analysis study sought to address a gap in literature in terms of examining the impact of leadership styles of principals on teacher satisfaction and teacher…

Redesigning Principal Internships: Practicing Principals' Perspectives

Science.gov (United States)

Anast-May, Linda; Buckner, Barbara; Geer, Gregory

2011-01-01

Internship programs too often do not provide the types of experiences that effectively bridge the gap between theory and practice and prepare school leaders who are capable of leading and transforming schools. To help address this problem, the current study is directed at providing insight into practicing principals' views of the types of…

The Future of Principal Evaluation

Science.gov (United States)

Clifford, Matthew; Ross, Steven

2012-01-01

The need to improve the quality of principal evaluation systems is long overdue. Although states and districts generally require principal evaluations, research and experience tell that many state and district evaluations do not reflect current standards and practices for principals, and that evaluation is not systematically administered. When…

Preparing Principals as Instructional Leaders: Perceptions of University Faculty, Expert Principals, and Expert Teacher Leaders

Science.gov (United States)

Taylor Backor, Karen; Gordon, Stephen P.

2015-01-01

Although research has established links between the principal's instructional leadership and student achievement, there is considerable concern in the literature concerning the capacity of principal preparation programs to prepare instructional leaders. This study interviewed educational leadership faculty as well as expert principals and teacher…

School Principals' Emotional Coping Process

Science.gov (United States)

Poirel, Emmanuel; Yvon, Frédéric

2014-01-01

The present study examines the emotional coping of school principals in Quebec. Emotional coping was measured by stimulated recall; six principals were filmed during a working day and presented a week later with their video showing stressful encounters. The results show that school principals experience anger because of reproaches from staff…

ENTERPRISE RESOURCE STRATEGIC PLANNING: TARGET CHOICE TECHNIQUES

Directory of Open Access Journals (Sweden)

A. S. Lankin

2011-01-01

Full Text Available Choice of the targets is one of most important elements of the resource planning system. Particular feature of the strategic planning is development of future alternatives for the enterprise. Main resource strategic planning cycle elements: examination of principal external and internal environment components; forming the company mission; development of long-term targets; concretization of the long-term targets through short-term aims; examination of strategies and final choice.

Predicting ground contact events for a continuum of gait types: An application of targeted machine learning using principal component analysis.

Science.gov (United States)

Osis, Sean T; Hettinga, Blayne A; Ferber, Reed

2016-05-01

An ongoing challenge in the application of gait analysis to clinical settings is the standardized detection of temporal events, with unobtrusive and cost-effective equipment, for a wide range of gait types. The purpose of the current study was to investigate a targeted machine learning approach for the prediction of timing for foot strike (or initial contact) and toe-off, using only kinematics for walking, forefoot running, and heel-toe running. Data were categorized by gait type and split into a training set (∼30%) and a validation set (∼70%). A principal component analysis was performed, and separate linear models were trained and validated for foot strike and toe-off, using ground reaction force data as a gold-standard for event timing. Results indicate the model predicted both foot strike and toe-off timing to within 20ms of the gold-standard for more than 95% of cases in walking and running gaits. The machine learning approach continues to provide robust timing predictions for clinical use, and may offer a flexible methodology to handle new events and gait types. Copyright © 2016 Elsevier B.V. All rights reserved.

How To Select a Good Assistant Principal.

Science.gov (United States)

Holman, Linda J.

1997-01-01

Notes that a well-structured job profile and interview can provide insight into the key qualities of an effective assistant principal. These include organizational skills, basic accounting knowledge, interpersonal skills, dependability, strong work ethic, effective problem-solving skills, leadership skills, written communication skills,…

Principal Time Management Skills: Explaining Patterns in Principals' Time Use, Job Stress, and Perceived Effectiveness

Science.gov (United States)

Grissom, Jason A.; Loeb, Susanna; Mitani, Hajime

2015-01-01

Purpose: Time demands faced by school principals make principals' work increasingly difficult. Research outside education suggests that effective time management skills may help principals meet job demands, reduce job stress, and improve their performance. The purpose of this paper is to investigate these hypotheses. Design/methodology/approach:…

3-D MDT with spherical targets by bilinear interpolation for determining blood velocity profiles including the vessel wall effect

Science.gov (United States)

Choomphon-anomakhun, Natthaphon; Natenapit, Mayuree

2018-02-01

A numerical simulation of three-dimensional (3-D) implant assisted-magnetic drug targeting (IA-MDT) using ferromagnetic spherical targets, including the effect from the vessel wall on the blood flow, is presented. The targets were implanted within arterioles and subjected to an externally uniform applied magnetic field in order to increase the effectiveness of targeting magnetic drug carrier particles (MDCPs). The capture area (As) of the MDCPs was determined by inspection of the particle trajectories simulated from the particle equations of motion. The blood flow velocities at any particle position around the target were obtained by applying bilinear interpolation to the numerical blood velocity data. The effects on As of the type of ferromagnetic materials in the targets and MDCPs, average blood flow rates, mass fraction of the ferromagnetic material in the MDCPs, average radii of MDCPs (Rp) and the externally applied magnetic field strength (μ0H0) were evaluated. Furthermore, the appropriate μ0H0 and Rp for the IA-MDT design is suggested. In the case of the SS409 target and magnetite MDCPs, dimensionless capture areas ranging from 4.1- to 12.4 and corresponding to particle capture efficiencies of 31-94% were obtained with Rp ranging from 100- to 500 nm, weight fraction of 80%, μ0H0 of 0.6 T and an average blood flow rate of 0.01 ms-1. In addition, the more general 3-D modelling of IA-MDT in this work is applicable to IA-MDT using spherical targets implanted within blood vessels for both laminar and potential blood flows including the wall effect.

Principal Self-Efficacy, Teacher Perceptions of Principal Performance, and Teacher Job Satisfaction

Science.gov (United States)

Evans, Molly Lynn

2016-01-01

In public schools, the principal's role is of paramount importance in influencing teachers to excel and to keep their job satisfaction high. The self-efficacy of leaders is an important characteristic of leadership, but this issue has not been extensively explored in school principals. Using internet-based questionnaires, this study obtained…

Evaluation of Principal Performance in Public and Private Sector Schools

OpenAIRE

Akhtar, Iram; Cheema, Khaliq Ur Rehman

2013-01-01

The purpose of this study is to analyze the performance in context of student learning of principals in public sector and private sector schools. For this purpose five main domains were used as variables are: 1) teaching, learning and professional growth, 2) Inter-personal and inter-professional relationship and collaboration, 3) Parent and faculty involvement in decision making, 4) Vision and values, 5) Innovation and change. The population for this study was selected randomly. The target sa...

Targeting Quiescence in Prostate Cancer

Science.gov (United States)

2017-10-01

AWARD NUMBER: W81XWH-15-1-0413 TITLE: Targeting Quiescence in Prostate Cancer PRINCIPAL INVESTIGATOR: Laura Buttitta CONTRACTING...Quiescence in Prostate Cancer 5a. CONTRACT NUMBER Targeting uiescence in Prostate Cancer 5b. GRANT NUMBER W81XWH-15-1-0413 5c. PROGRAM ELEMENT NUMBER 6...NOTES 14. ABSTRACT A major problem in prostate cancer is finding and eliminating the non-proliferating or “quiescent” cancer cells. This is because early

Principals Who Think Like Teachers

Science.gov (United States)

Fahey, Kevin

2013-01-01

Being a principal is a complex job, requiring quick, on-the-job learning. But many principals already have deep experience in a role at the very essence of the principalship. They know how to teach. In interviews with principals, Fahey and his colleagues learned that thinking like a teacher was key to their work. Part of thinking the way a teacher…

Planar optical waveguide based sandwich assay sensors and processes for the detection of biological targets including protein markers, pathogens and cellular debris

Science.gov (United States)

Martinez, Jennifer S [Santa Fe, NM; Swanson, Basil I [Los Alamos, NM; Grace, Karen M [Los Alamos, NM; Grace, Wynne K [Los Alamos, NM; Shreve, Andrew P [Santa Fe, NM

2009-06-02

An assay element is described including recognition ligands bound to a film on a single mode planar optical waveguide, the film from the group of a membrane, a polymerized bilayer membrane, and a self-assembled monolayer containing polyethylene glycol or polypropylene glycol groups therein and an assay process for detecting the presence of a biological target is described including injecting a biological target-containing sample into a sensor cell including the assay element, with the recognition ligands adapted for binding to selected biological targets, maintaining the sample within the sensor cell for time sufficient for binding to occur between selected biological targets within the sample and the recognition ligands, injecting a solution including a reporter ligand into the sensor cell; and, interrogating the sample within the sensor cell with excitation light from the waveguide, the excitation light provided by an evanescent field of the single mode penetrating into the biological target-containing sample to a distance of less than about 200 nanometers from the waveguide thereby exciting the fluorescent-label in any bound reporter ligand within a distance of less than about 200 nanometers from the waveguide and resulting in a detectable signal.

Trust Me, Principal, or Burn Out! The Relationship between Principals' Burnout and Trust in Students and Parents

Science.gov (United States)

Ozer, Niyazi

2013-01-01

The purpose of this study was to determine the primary school principals' views on trust in students and parents and also, to explore the relationships between principals' levels of professional burnout and their trust in students and parents. To this end, Principal Trust Survey and Friedman Principal Burnout scales were administered on 119…

EphB1 as a Novel Drug Target to Combat Pain and Addiction

Science.gov (United States)

2015-09-01

EphB1  as  a  Novel  Drug  Target  to  Combat  Pain  and   Addiction   Principal  Investigator  Name:   Mark...Principal  Investigator   Phone  and  Email:   Phone :  214-­‐645-­‐5916   Email:  Mark.Henkemeyer@UTSouthwestern.edu   Report  Date...31 Aug 2015 4. TITLE AND SUBTITLE EphB1 as a Novel Drug Target to Combat Pain and Addiction 5a. CONTRACT NUMBER EphB1 as a Novel Drug Target to

Exploring the Impact of Applicants' Gender and Religion on Principals' Screening Decisions for Assistant Principal Applicants

Science.gov (United States)

Bon, Susan C.

2009-01-01

In this experimental study, a national random sample of high school principals (stratified by gender) were asked to evaluate hypothetical applicants whose resumes varied by religion (Jewish, Catholic, nondenominational) and gender (male, female) for employment as assistant principals. Results reveal that male principals rate all applicants higher…

Cellular and molecular mechanisms of HIV-1 integration targeting.

Science.gov (United States)

Engelman, Alan N; Singh, Parmit K

2018-07-01

Integration is central to HIV-1 replication and helps mold the reservoir of cells that persists in AIDS patients. HIV-1 interacts with specific cellular factors to target integration to interior regions of transcriptionally active genes within gene-dense regions of chromatin. The viral capsid interacts with several proteins that are additionally implicated in virus nuclear import, including cleavage and polyadenylation specificity factor 6, to suppress integration into heterochromatin. The viral integrase protein interacts with transcriptional co-activator lens epithelium-derived growth factor p75 to principally position integration within gene bodies. The integrase additionally senses target DNA distortion and nucleotide sequence to help fine-tune the specific phosphodiester bonds that are cleaved at integration sites. Research into virus-host interactions that underlie HIV-1 integration targeting has aided the development of a novel class of integrase inhibitors and may help to improve the safety of viral-based gene therapy vectors.

Principals' Perceptions of Politics

Science.gov (United States)

Tooms, Autumn K.; Kretovics, Mark A.; Smialek, Charles A.

2007-01-01

This study is an effort to examine principals' perceptions of workplace politics and its influence on their productivity and efficacy. A survey was used to explore the perceptions of current school administrators with regard to workplace politics. The instrument was disseminated to principals serving public schools in one Midwestern state in the…

Principal Investigator-in-a-Box

Science.gov (United States)

Young, Laurence R.

1999-01-01

Investigator, and combine that with real-time data available in space in order to advise the astronaut about how to proceed in real time. [PI] advises the astronaut during the progress of an experiment in much the same way a real Principal Investigator might do while looking over the astronaut's shoulder. In its original application, [PI] mimicked several of the tasks of the Principal Investigator, including data quality monitoring, troubleshooting, prescheduling, protocol management and "interesting data" detection. The proposed research focuses on the efficacy of this technique as applied to the data quality monitoring and troubleshooting aspects of [PI].

Theranostics Targeting Metastatic Breast Cancer

Science.gov (United States)

2017-10-01

AWARD NUMBER: W81XWH-15-1-0390 TITLE: Theranostics Targeting Metastatic Breast Cancer PRINCIPAL INVESTIGATOR: Zheng Li CONTRACTING ORGANIZATION...Breast Cancer 5b. GRANT NUMBER W81XWH-15-1-0390 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) 5d. PROJECT NUMBER Zheng Li 5e. TASK NUMBER 5f. WORK UNIT...14 Theranostics Targeting Metastatic Breast  Cancer   A. Introduction (1paragraph) The overall goal of this proposal is to prepare TrkC

Renewing the Principal Pipeline

Science.gov (United States)

Turnbull, Brenda J.

2015-01-01

The work principals do has always mattered, but as the demands of the job increase, it matters even more. Perhaps once they could maintain safety and order and call it a day, but no longer. Successful principals today must also lead instruction and nurture a productive learning community for students, teachers, and staff. They set the tone for the…

Challenges to Library Materials from Principals in United States Secondary Schools--A "Victory" of Sorts.

Science.gov (United States)

Hopkins, Dianne McAfee

1995-01-01

Examines challenges to school library materials initiated by principals in public middle, junior, and senior high school libraries based on a 1990 survey. A review of literature emphasizing the leadership of principals, their role in school library program development, and the principal and school library censorship is included. (Author/LRW)

Principal Ports

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — Principal Ports are defined by port limits or US Army Corps of Engineers (USACE) projects, these exclude non-USACE projects not authorized for publication. The...

Perceptions of Beginning Public School Principals.

Science.gov (United States)

Lyons, James E.

1993-01-01

Summarizes a study to determine principal's perceptions of their competency in primary responsibility areas and their greatest challenges and frustrations. Beginning principals are challenged by delegating responsibilities and becoming familiar with the principal's role, the local school, and school operations. Their major frustrations are role…

Multiscale principal component analysis

International Nuclear Information System (INIS)

Akinduko, A A; Gorban, A N

2014-01-01

Principal component analysis (PCA) is an important tool in exploring data. The conventional approach to PCA leads to a solution which favours the structures with large variances. This is sensitive to outliers and could obfuscate interesting underlying structures. One of the equivalent definitions of PCA is that it seeks the subspaces that maximize the sum of squared pairwise distances between data projections. This definition opens up more flexibility in the analysis of principal components which is useful in enhancing PCA. In this paper we introduce scales into PCA by maximizing only the sum of pairwise distances between projections for pairs of datapoints with distances within a chosen interval of values [l,u]. The resulting principal component decompositions in Multiscale PCA depend on point (l,u) on the plane and for each point we define projectors onto principal components. Cluster analysis of these projectors reveals the structures in the data at various scales. Each structure is described by the eigenvectors at the medoid point of the cluster which represent the structure. We also use the distortion of projections as a criterion for choosing an appropriate scale especially for data with outliers. This method was tested on both artificial distribution of data and real data. For data with multiscale structures, the method was able to reveal the different structures of the data and also to reduce the effect of outliers in the principal component analysis

A principal components model of soundscape perception.

Science.gov (United States)

Axelsson, Östen; Nilsson, Mats E; Berglund, Birgitta

2010-11-01

There is a need for a model that identifies underlying dimensions of soundscape perception, and which may guide measurement and improvement of soundscape quality. With the purpose to develop such a model, a listening experiment was conducted. One hundred listeners measured 50 excerpts of binaural recordings of urban outdoor soundscapes on 116 attribute scales. The average attribute scale values were subjected to principal components analysis, resulting in three components: Pleasantness, eventfulness, and familiarity, explaining 50, 18 and 6% of the total variance, respectively. The principal-component scores were correlated with physical soundscape properties, including categories of dominant sounds and acoustic variables. Soundscape excerpts dominated by technological sounds were found to be unpleasant, whereas soundscape excerpts dominated by natural sounds were pleasant, and soundscape excerpts dominated by human sounds were eventful. These relationships remained after controlling for the overall soundscape loudness (Zwicker's N(10)), which shows that 'informational' properties are substantial contributors to the perception of soundscape. The proposed principal components model provides a framework for future soundscape research and practice. In particular, it suggests which basic dimensions are necessary to measure, how to measure them by a defined set of attribute scales, and how to promote high-quality soundscapes.

Andragogical Practices of School Principals in Developing the Leadership Capacities of Assistant Principals

Science.gov (United States)

McDaniel, Luther

2017-01-01

The purpose of this mixed methods study was to assess school principals' perspectives of the extent to which they apply the principles of andragogy to the professional development of assistant principals in their schools. This study was conducted in school districts that constitute a RESA area in a southeastern state. The schools in these…

Efficient training of multilayer perceptrons using principal component analysis

International Nuclear Information System (INIS)

Bunzmann, Christoph; Urbanczik, Robert; Biehl, Michael

2005-01-01

A training algorithm for multilayer perceptrons is discussed and studied in detail, which relates to the technique of principal component analysis. The latter is performed with respect to a correlation matrix computed from the example inputs and their target outputs. Typical properties of the training procedure are investigated by means of a statistical physics analysis in models of learning regression and classification tasks. We demonstrate that the procedure requires by far fewer examples for good generalization than traditional online training. For networks with a large number of hidden units we derive the training prescription which achieves, within our model, the optimal generalization behavior

13 CFR 115.36 - Indemnity settlements and reinstatement of Principal.

Science.gov (United States)

2010-01-01

... for SBA's consideration must include current financial information, including financial statements... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false Indemnity settlements and reinstatement of Principal. 115.36 Section 115.36 Business Credit and Assistance SMALL BUSINESS ADMINISTRATION...

41 CFR 105-68.995 - Principal.

Science.gov (United States)

2010-07-01

... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Principal. 105-68.995 Section 105-68.995 Public Contracts and Property Management Federal Property Management Regulations System...-GOVERNMENTWIDE DEBARMENT AND SUSPENSION (NONPROCUREMENT) Definitions § 105-68.995 Principal. Principal means— (a...

New type of metal targets

International Nuclear Information System (INIS)

Bukharov, A.V.; Ankudinov, V.B.; Ogorodnikov, V.P.; Marukhin, Y.A.

2014-01-01

Now the technologies based on interaction of high-intensity beams with substance of a target are being intensively developed. As a target it is possible to use the new type of monodisperse metal targets. The principal advantages of new targets type are: target cooling isn't required; there is no induced activity: the target can be used many times; small dispersion on the speed, the size and interaction points with a beam. The basis of a target is the jet of molten metal, following in the vacuum chamber .Under the influence of the special disturbance superimposed on the liquid jet, the jet disintegrated into identical drops. In the vacuum chamber the drops freeze and form into the solid granules. It is possible to receive monodisperse targets from different metals, alloys and salts (diameter of targets is from 30 .m to 1.5 mm). Dispersion by the sizes and speed is less than 1%. The technique allows to receive not only continuous targets, but also hollow targets with dispersion on thickness of wall within 1...2%.

Principal-Counselor Collaboration and School Climate

Science.gov (United States)

Rock, Wendy D.; Remley, Theodore P.; Range, Lillian M.

2017-01-01

Examining whether principal-counselor collaboration and school climate were related, researchers sent 4,193 surveys to high school counselors in the United States and received 419 responses. As principal-counselor collaboration increased, there were increases in counselors viewing the principal as supportive, the teachers as regarding one another…

12 CFR 561.39 - Principal office.

Science.gov (United States)

2010-01-01

... 12 Banks and Banking 5 2010-01-01 2010-01-01 false Principal office. 561.39 Section 561.39 Banks and Banking OFFICE OF THRIFT SUPERVISION, DEPARTMENT OF THE TREASURY DEFINITIONS FOR REGULATIONS AFFECTING ALL SAVINGS ASSOCIATIONS § 561.39 Principal office. The term principal office means the home...

Teacher Supervision Practices and Principals' Characteristics

Science.gov (United States)

April, Daniel; Bouchamma, Yamina

2015-01-01

A questionnaire was used to determine the individual and collective teacher supervision practices of school principals and vice-principals in Québec (n = 39) who participated in a research-action study on pedagogical supervision. These practices were then analyzed in terms of the principals' sociodemographic and socioprofessional characteristics…

COPD phenotype description using principal components analysis

DEFF Research Database (Denmark)

Roy, Kay; Smith, Jacky; Kolsum, Umme

2009-01-01

BACKGROUND: Airway inflammation in COPD can be measured using biomarkers such as induced sputum and Fe(NO). This study set out to explore the heterogeneity of COPD using biomarkers of airway and systemic inflammation and pulmonary function by principal components analysis (PCA). SUBJECTS...... AND METHODS: In 127 COPD patients (mean FEV1 61%), pulmonary function, Fe(NO), plasma CRP and TNF-alpha, sputum differential cell counts and sputum IL8 (pg/ml) were measured. Principal components analysis as well as multivariate analysis was performed. RESULTS: PCA identified four main components (% variance...... associations between the variables within components 1 and 2. CONCLUSION: COPD is a multi dimensional disease. Unrelated components of disease were identified, including neutrophilic airway inflammation which was associated with systemic inflammation, and sputum eosinophils which were related to increased Fe...

Developing Principal Instructional Leadership through Collaborative Networking

Science.gov (United States)

Cone, Mariah Bahar

2010-01-01

This study examines what occurs when principals of urban schools meet together to learn and improve their instructional leadership in collaborative principal networks designed to support, sustain, and provide ongoing principal capacity building. Principal leadership is considered second only to teaching in its ability to improve schools, yet few…

Principal Stability and the Rural Divide

Science.gov (United States)

Pendola, Andrew; Fuller, Edward J.

2018-01-01

This article examines the unique features of the rural school context and how these features are associated with the stability of principals in these schools. Given the small but growing literature on the characteristics of rural principals, this study presents an exploratory analysis of principal stability across schools located in different…

A principal-agent Model of corruption

NARCIS (Netherlands)

Groenendijk, Nico

1997-01-01

One of the new avenues in the study of political corruption is that of neo-institutional economics, of which the principal-agent theory is a part. In this article a principal-agent model of corruption is presented, in which there are two principals (one of which is corrupting), and one agent (who is

Principal Curves on Riemannian Manifolds.

Science.gov (United States)

Hauberg, Soren

2016-09-01

Euclidean statistics are often generalized to Riemannian manifolds by replacing straight-line interpolations with geodesic ones. While these Riemannian models are familiar-looking, they are restricted by the inflexibility of geodesics, and they rely on constructions which are optimal only in Euclidean domains. We consider extensions of Principal Component Analysis (PCA) to Riemannian manifolds. Classic Riemannian approaches seek a geodesic curve passing through the mean that optimizes a criteria of interest. The requirements that the solution both is geodesic and must pass through the mean tend to imply that the methods only work well when the manifold is mostly flat within the support of the generating distribution. We argue that instead of generalizing linear Euclidean models, it is more fruitful to generalize non-linear Euclidean models. Specifically, we extend the classic Principal Curves from Hastie & Stuetzle to data residing on a complete Riemannian manifold. We show that for elliptical distributions in the tangent of spaces of constant curvature, the standard principal geodesic is a principal curve. The proposed model is simple to compute and avoids many of the pitfalls of traditional geodesic approaches. We empirically demonstrate the effectiveness of the Riemannian principal curves on several manifolds and datasets.

Anglo-American views of Gavrilo Princip

Directory of Open Access Journals (Sweden)

Markovich Slobodan G.

2015-01-01

Full Text Available The paper deals with Western (Anglo-American views on the Sarajevo assassination/attentat and Gavrilo Princip. Articles on the assassination and Princip in two leading quality dailies (The Times and The New York Times have particularly been analysed as well as the views of leading historians and journalists who covered the subject including: R. G. D. Laffan, R. W. Seton-Watson, Winston Churchill, Sidney Fay, Bernadotte Schmitt, Rebecca West, A. J. P. Taylor, Vladimir Dedijer, Christopher Clark and Tim Butcher. In the West, the original general condemnation of the assassination and its main culprits was challenged when Rebecca West published her famous travelogue on Yugoslavia in 1941. Another Brit, the remarkable historian A. J. P. Taylor, had a much more positive view on the Sarajevo conspirators and blamed Germany and Austria-Hungary for the outbreak of the Great War. A turning point in Anglo-American perceptions was the publication of Vladimir Dedijer’s monumental book The Road to Sarajevo (1966, which humanised the main conspirators, a process initiated by R. West. Dedijer’s book was translated from English into all major Western languages and had an immediate impact on the understanding of the Sarajevo assassination. The rise of national antagonisms in Bosnia gradually alienated Princip from Bosnian Muslims and Croats, a process that began in the 1980s and was completed during the wars of the Yugoslav succession. Although all available sources clearly show that Princip, an ethnic Serb, gradually developed a broader Serbo-Croat and Yugoslav identity, he was ethnified and seen exclusively as a Serb by Bosnian Croats and Bosniaks and Western journalists in the 1990s. In the past century imagining Princip in Serbia and the West involved a whole spectrum of views. In interwar Anglo-American perceptions he was a fanatic and lunatic. He became humanised by Rebecca West (1941, A. J. P. Taylor showed understanding for his act (1956, he was fully

Uniform irradiation of adjustable target spots in high-power laser driver

International Nuclear Information System (INIS)

Jiang Xiujuan; Li Jinghui; Li Huagang; Li Yang; Lin Zunqi

2011-01-01

For smoothing and shaping the on-target laser patterns flexibly in high-power laser drivers, a scheme has been developed that includes a zoom lens array and two-dimensional smoothing by spectral dispersion (SSD). The size of the target pattern can be controlled handily by adjusting the focal length of the zoom lens array, while the profile of the pattern can be shaped by fine tuning the distance between the target and the focal plane of the principal focusing lens. High-frequency stripes inside the pattern caused by beamlet interference are wiped off by spectral dispersion. Detailed simulations indicate that SSD works somewhat differently for spots of different sizes. For small spots, SSD mainly smooths the intensity modulation of low-to-middle spatial frequency, while for large spots, SSD sweeps the fine speckle structure to reduce nonuniformity of middle-to-high frequency. Spatial spectra of the target patterns are given and their uniformity is evaluated.

MicroRNA-145 targets YES and STAT1 in colon cancer cells

DEFF Research Database (Denmark)

Gregersen, Lea H; Jacobsen, Anders B; Frankel, Lisa

2010-01-01

miRNA overexpression. Gene Ontology analysis showed an overrepresentation of genes involved in cell death, cellular growth and proliferation, cell cycle, gene expression and cancer. A number of the identified miRNA targets have previously been implicated in cancer, including YES, FSCN1, ADAM17, BIRC2......, VANGL1 as well as the transcription factor STAT1. Both YES and STAT1 were verified as direct miR-145 targets. CONCLUSIONS/SIGNIFICANCE: The study identifies and validates new cancer-relevant direct targets of miR-145 in colon cancer cells and hereby adds important mechanistic understanding of the tumor......BACKGROUND: MicroRNAs (miRNAs) have emerged as important gene regulators and are recognized as key players in tumorigenesis. miR-145 is reported to be down-regulated in several cancers, but knowledge of its targets in colon cancer remains limited. METHODOLOGY/PRINCIPAL FINDINGS: To investigate...

Principal Leadership for Technology-enhanced Learning in Science

Science.gov (United States)

Gerard, Libby F.; Bowyer, Jane B.; Linn, Marcia C.

2008-02-01

Reforms such as technology-enhanced instruction require principal leadership. Yet, many principals report that they need help to guide implementation of science and technology reforms. We identify strategies for helping principals provide this leadership. A two-phase design is employed. In the first phase we elicit principals' varied ideas about the Technology-enhanced Learning in Science (TELS) curriculum materials being implemented by teachers in their schools, and in the second phase we engage principals in a leadership workshop designed based on the ideas they generated. Analysis uses an emergent coding scheme to categorize principals' ideas, and a knowledge integration framework to capture the development of these ideas. The analysis suggests that principals frame their thinking about the implementation of TELS in terms of: principal leadership, curriculum, educational policy, teacher learning, student outcomes and financial resources. They seek to improve their own knowledge to support this reform. The principals organize their ideas around individual school goals and current political issues. Principals prefer professional development activities that engage them in reviewing curricula and student work with other principals. Based on the analysis, this study offers guidelines for creating learning opportunities that enhance principals' leadership abilities in technology and science reform.

Catholic School Principal Job Satisfaction: Keys to Retention and Recruitment

Science.gov (United States)

Fraser, Jennifer; Brock, Barbara L.

2006-01-01

This article presents a study on principal retention in New South Wales, Australia. Factors in job retention included economic security, role enjoyment, and the opportunity to contribute. Disincentives to the principalship included lack of support from the employing authority, inadequate pay, isolation, growing responsibilities, difficult parents,…

Detecting 3-D rotational motion and extracting target information from the principal component analysis of scatterer range histories

CSIR Research Space (South Africa)

Nel, W

2009-10-01

Full Text Available to estimate the 3-D position of scatterers as a by-product of the analysis. The technique is based on principal component analysis of accurate scatterer range histories and is shown only in simulation. Future research should focus on practical application....

Emotional Intelligence: The Contribution to Leadership Skills in Female Catholic Elementary School Principals

Science.gov (United States)

Dziewior, Jane M.

2009-01-01

Past research was not clear what the relationship was between emotional intelligence (EI) and leadership style for school principals. This researcher examined EI and its contribution to leadership skills of 22 female Catholic elementary school principals. The method included a self-reported questionnaire of leadership style and EI to explore if…

26 CFR 1.446-3 - Notional principal contracts.

Science.gov (United States)

2010-04-01

... payments. (5) Caps and floors that are significantly in-the-money. [Reserved] (6) Examples. (h) Termination... principal contract for a taxable year is included in or deducted from gross income for that taxable year... payment (as defined in paragraph (h) of this section). Examples of nonperiodic payments are the premium...

Triangulating Principal Effectiveness: How Perspectives of Parents, Teachers, and Assistant Principals Identify the Central Importance of Managerial Skills. Working Paper 35

Science.gov (United States)

Grissom, Jason A.; Loeb, Susanna

2009-01-01

While the importance of effective principals is undisputed, few studies have addressed what specific skills principals need to promote school success. This study draws on unique data combining survey responses from principals, assistant principals, teachers and parents with rich administrative data to identify which principal skills matter most…

Principal components

NARCIS (Netherlands)

Hallin, M.; Hörmann, S.; Piegorsch, W.; El Shaarawi, A.

2012-01-01

Principal Components are probably the best known and most widely used of all multivariate analysis techniques. The essential idea consists in performing a linear transformation of the observed k-dimensional variables in such a way that the new variables are vectors of k mutually orthogonal

Innovation Management Perceptions of Principals

Science.gov (United States)

Bakir, Asli Agiroglu

2016-01-01

This study is aimed to determine the perceptions of principals about innovation management and to investigate whether there is a significant difference in this perception according to various parameters. In the study, descriptive research model is used and universe is consisted from principals who participated in "Acquiring Formation Course…

Targeting Discoidin Domain Receptors in Prostate Cancer

Science.gov (United States)

2017-08-01

AWARD NUMBER: W81XWH-15-1-0226 TITLE: Targeting Discoidin Domain Receptors in Prostate Cancer PRINCIPAL INVESTIGATOR: Dr. Rafael Fridman...AND SUBTITLE 5a. CONTRACT NUMBER Targeting Discoidin Domain Receptors in Prostate Cancer 5b. GRANT NUMBER W81XWH-15-1-0226 5c. PROGRAM ELEMENT...response to collagen in prostate cancer. The project’s goal is to define the expression and therapeutic potential of DDRs in prostate cancer. During

Novel Targeted Therapies for Inflammatory Breast Cancer

Science.gov (United States)

2017-10-01

AWARD NUMBER: W81XWH-16-1-0461 TITLE: Novel Targeted Therapies for Inflammatory Breast Cancer PRINCIPAL INVESTIGATOR: Jose Silva CONTRACTING...CONTRACT NUMBER Novel Targeted Therapies for Inflammatory Breast Cancer 5b. GRANT NUMBER W81XWH-16-1-0461 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) l 5d...NOTES 14. ABSTRACT Inflammatory breast cancer (IBC, ~5% of all breast cancers ) is the most lethal form of breast cancer , presenting a 5- year

Targeting Stromal Recruitment by Prostate Cancer Cells

Science.gov (United States)

2006-03-01

Ensinger, C., Tumer , Z., Tommerup, N. et al.: Hedgehog signaling in small-cell lung cancer : frequent in vivo but a rare event in vitro. Lung Cancer , 52...W81XWH-04-1-0157 TITLE: Targeting Stromal Recruitment by Prostate Cancer Cells PRINCIPAL INVESTIGATOR: Jingxian Zhang, Ph.D...DATES COVERED (From - To) 15 Feb 2004 – 14 Feb 2006 4. TITLE AND SUBTITLE 5a. CONTRACT NUMBER Targeting Stromal Recruitment by Prostate Cancer

Principals' instructional management skills and middle school science teacher job satisfaction

Science.gov (United States)

Gibbs-Harper, Nzinga A.

The purpose of this research study was to determine if a relationship exists between teachers' perceptions of principals' instructional leadership behaviors and middle school teacher job satisfaction. Additionally, this study sought to assess whether principal's instructional leadership skills were predictors of middle school teachers' satisfaction with work itself. This study drew from 13 middle schools in an urban Mississippi school district. Participants included teachers who taught science. Each teacher was given the Principal Instructional Management Rating Scale (PIMRS; Hallinger, 2011) and the Teacher Job Satisfaction Questionnaire (TJSQ; Lester, 1987) to answer the research questions. The study was guided by two research questions: (a) Is there a relationship between the independent variables Defining the School's Mission, Managing the Instructional Program, and Developing the School Learning Climate Program and the dependent variable Work Itself?; (b) Are Defining the School's Mission, Managing the Instructional Program, and Developing the School Learning Climate Program predictors of Work Itself? The Pearson's correlation and multiple regression analysis were utilized to examine the relationship between the three dimensions of principals' instructional leadership and teacher satisfaction with work itself. The data revealed that there was a strong, positive correlation between all three dimensions of principals' instructional leadership and teacher satisfaction with work itself. However, the multiple regression analysis determined that teachers' perceptions of principals' instructional management skills is a slight predictor of Defining the School's Mission only.

Time Management for New Principals

Science.gov (United States)

Ruder, Robert

2008-01-01

Becoming a principal is a milestone in an educator's professional life. The principalship is an opportunity to provide leadership that will afford students opportunities to thrive in a nurturing and supportive environment. Despite the continuously expanding demands of being a new principal, effective time management will enable an individual to be…

What Motivates Principals?

Science.gov (United States)

Iannone, Ron

1973-01-01

Achievement and recognition were mentioned as factors appearing with greater frequency in principal's job satisfactions; school district policy and interpersonal relations were mentioned as job dissatisfactions. (Editor)

The Unsung Role of the Career Assistant Principal.

Science.gov (United States)

Marshall, Catherine

Common views of the assistant principal (AP) as the "Marine Corps sergeant type" with nowhere better to be are outdated. Career APs have diverse roles in school administration, often including, but not limited to, discipline. Many career APs find rewards in working with children and put high value on having a balanced personal life. Two…

Bureaucratic Control and Principal Role.

Science.gov (United States)

Bezdek, Robert; And Others

The purposes of this study were to determine the manner in which the imposition of increased bureaucratic control over principals influenced their allocation of time to tasks and to investigate principals' perceptions of the changes in their roles brought about by this increased control. The specific bureaucratic control system whose effects were…

Targeting the ECM to Enhance Drug Delivery in Nf1-Associated Nerve Sheath Tumors

Science.gov (United States)

2016-10-01

development of the principal discipline(s) of the project? • We have learned that the drug PEGPH20, which degrades a component of connective tissue called...AWARD NUMBER: W81XWH-15-1-0114 TITLE: Targeting the ECM to Enhance Drug Delivery in Nf1-Associated Nerve Sheath Tumors PRINCIPAL INVESTIGATOR...14 Sep 2016 4. TITLE AND SUBTITLE 5a. CONTRACT NUMBER NF140089 Targeting the ECM to Enhance Drug Delivery in Nf1-Associated Nerve Sheath Tumors 5b

School Principals' Sources of Knowledge

Science.gov (United States)

Perkins, Arland Early

2014-01-01

The purpose of this study was to determine what sources of professional knowledge are available to principals in 1 rural East Tennessee school district. Qualitative research methods were applied to gain an understanding of what sources of knowledge are used by school principals in 1 rural East Tennessee school district and the barriers they face…

Reduction of symplectic principal R-bundles

International Nuclear Information System (INIS)

Lacirasella, Ignazio; Marrero, Juan Carlos; Padrón, Edith

2012-01-01

We describe a reduction process for symplectic principal R-bundles in the presence of a momentum map. These types of structures play an important role in the geometric formulation of non-autonomous Hamiltonian systems. We apply this procedure to the standard symplectic principal R-bundle associated with a fibration π:M→R. Moreover, we show a reduction process for non-autonomous Hamiltonian systems on symplectic principal R-bundles. We apply these reduction processes to several examples. (paper)

Molecular fingerprinting of principal neurons in the rodent hippocampus: A neuroinformatics approach.

Science.gov (United States)

Hamilton, D J; White, C M; Rees, C L; Wheeler, D W; Ascoli, G A

2017-09-10

Neurons are often classified by their morphological and molecular properties. The online knowledge base Hippocampome.org primarily defines neuron types from the rodent hippocampal formation based on their main neurotransmitter (glutamate or GABA) and the spatial distributions of their axons and dendrites. For each neuron type, this open-access resource reports any and all published information regarding the presence or absence of known molecular markers, including calcium-binding proteins, neuropeptides, receptors, channels, transcription factors, and other molecules of biomedical relevance. The resulting chemical profile is relatively sparse: even for the best studied neuron types, the expression or lack thereof of fewer than 70 molecules has been firmly established to date. The mouse genome-wide in situ hybridization mapping of the Allen Brain Atlas provides a wealth of data that, when appropriately analyzed, can substantially augment the molecular marker knowledge in Hippocampome.org. Here we focus on the principal cell layers of dentate gyrus (DG), CA3, CA2, and CA1, which together contain approximately 90% of hippocampal neurons. These four anatomical parcels are densely packed with somata of mostly excitatory projection neurons. Thus, gene expression data for those layers can be justifiably linked to the respective principal neuron types: granule cells in DG and pyramidal cells in CA3, CA2, and CA1. In order to enable consistent interpretation across genes and regions, we screened the whole-genome dataset against known molecular markers of those neuron types. The resulting threshold values allow over 6000 very-high confidence (>99.5%) expressed/not-expressed assignments, expanding the biochemical information content of Hippocampome.org more than five-fold. Many of these newly identified molecular markers are potential pharmacological targets for major neurological and psychiatric conditions. Furthermore, our approach yields reasonable expression

New Principal Coaching as a Safety Net

Science.gov (United States)

Celoria, Davide; Roberson, Ingrid

2015-01-01

This study examines new principal coaching as an induction process and explores the emotional dimensions of educational leadership. Twelve principal coaches and new principals--six of each--participated in this qualitative study that employed emergent coding (Creswell, 2008; Denzin, 2005; Glaser & Strauss, 1998; Spradley, 1979). The major…

Modelling Monthly Mental Sickness Cases Using Principal ...

African Journals Online (AJOL)

The methodology was principal component analysis (PCA) using data obtained from the hospital to estimate regression coefficients and parameters. It was found that the principal component regression model that was derived was good predictive tool. The principal component regression model obtained was okay and this ...

Importance of an Effective Principal-Counselor Relationship

Science.gov (United States)

Edwards, LaWanda; Grace, Ronald; King, Gwendolyn

2014-01-01

An effective relationship between the principal and school counselor is essential when improving student achievement. To have an effective relationship, there must be communication, trust and respect, leadership, and collaborative planning between the principal and school counselor (College Board, 2011). Principals and school counselors are both…

Management Of Indiscipline Among Teachers By Principals Of ...

African Journals Online (AJOL)

This study compared the management of indiscipline among teachers by public and private school principals in Akwa Ibom State. The sample comprised four hundred and fifty (450) principals/vice principals randomly selected from a population of one thousand, four hundred and twenty eight (1,428) principals. The null ...

What Do Effective Principals Do?

Science.gov (United States)

Protheroe, Nancy

2011-01-01

Much has been written during the past decade about the changing role of the principal and the shift in emphasis from manager to instructional leader. Anyone in education, and especially principals themselves, could develop a mental list of responsibilities that fit within each of these realms. But research makes it clear that both those aspects of…

Targeting Histone Abnormality in Triple Negative Breast Cancer

Science.gov (United States)

2015-08-01

κB pathway in triple negative breast cancer . 8th International Nitric Oxide Conference & 6th International Nitrite/ Nitrate Conference, Cleveland, OH...1 AWARD NUMBER: W81XWH-14-1-0237 TITLE: Targeting Histone Abnormality in Triple-Negative Breast Cancer PRINCIPAL INVESTIGATOR: Yi...TITLE AND SUBTITLE 5a. CONTRACT NUMBER Targeting Histone Abnormality in Triple-Negative Breast Cancer 5b. GRANT NUMBER W81XWH-14-1-0237 5c

Difference in target definition using three different methods to include respiratory motion in radiotherapy of lung cancer.

Science.gov (United States)

Sloth Møller, Ditte; Knap, Marianne Marquard; Nyeng, Tine Bisballe; Khalil, Azza Ahmed; Holt, Marianne Ingerslev; Kandi, Maria; Hoffmann, Lone

2017-11-01

Minimizing the planning target volume (PTV) while ensuring sufficient target coverage during the entire respiratory cycle is essential for free-breathing radiotherapy of lung cancer. Different methods are used to incorporate the respiratory motion into the PTV. Fifteen patients were analyzed. Respiration can be included in the target delineation process creating a respiratory GTV, denoted iGTV. Alternatively, the respiratory amplitude (A) can be measured based on the 4D-CT and A can be incorporated in the margin expansion. The GTV expanded by A yielded GTV + resp, which was compared to iGTV in terms of overlap. Three methods for PTV generation were compared. PTV del (delineated iGTV expanded to CTV plus PTV margin), PTV σ (GTV expanded to CTV and A was included as a random uncertainty in the CTV to PTV margin) and PTV ∑ (GTV expanded to CTV, succeeded by CTV linear expansion by A to CTV + resp, which was finally expanded to PTV ∑ ). Deformation of tumor and lymph nodes during respiration resulted in volume changes between the respiratory phases. The overlap between iGTV and GTV + resp showed that on average 7% of iGTV was outside the GTV + resp implying that GTV + resp did not capture the tumor during the full deformable respiration cycle. A comparison of the PTV volumes showed that PTV σ was smallest and PTV Σ largest for all patients. PTV σ was in mean 14% (31 cm 3 ) smaller than PTV del , while PTV del was 7% (20 cm 3 ) smaller than PTV Σ . PTV σ yields the smallest volumes but does not ensure coverage of tumor during the full respiratory motion due to tumor deformation. Incorporating the respiratory motion in the delineation (PTV del ) takes into account the entire respiratory cycle including deformation, but at the cost, however, of larger treatment volumes. PTV Σ should not be used, since it incorporates the disadvantages of both PTV del and PTV σ .

The Principal as Academician: The Renewed Voice.

Science.gov (United States)

McAvoy, Brenda, Ed.

This collection of essays was written by principals who participated in the 1986-87 Humanities Seminar sponsored by the Principals' Institute of Georgia State University. The focus was "The Evolution of Intellectual Leadership." The roles of the principal as philosopher, historian, ethnician, writer and team member are examined through…

Leadership Coaching for Principals: A National Study

Science.gov (United States)

Wise, Donald; Cavazos, Blanca

2017-01-01

Surveys were sent to a large representative sample of public school principals in the United States asking if they had received leadership coaching. Comparison of responses to actual numbers of principals indicates that the sample represents the first national study of principal leadership coaching. Results indicate that approximately 50% of all…

Riccati transformations and principal solutions of discrete linear systems

International Nuclear Information System (INIS)

Ahlbrandt, C.D.; Hooker, J.W.

1984-01-01

Consider a second-order linear matrix difference equation. A definition of principal and anti-principal, or recessive and dominant, solutions of the equation are given and the existence of principal and anti-principal solutions and the essential uniqueness of principal solutions is proven

A Genealogical Interpretation of Principal Components Analysis

Science.gov (United States)

McVean, Gil

2009-01-01

Principal components analysis, PCA, is a statistical method commonly used in population genetics to identify structure in the distribution of genetic variation across geographical location and ethnic background. However, while the method is often used to inform about historical demographic processes, little is known about the relationship between fundamental demographic parameters and the projection of samples onto the primary axes. Here I show that for SNP data the projection of samples onto the principal components can be obtained directly from considering the average coalescent times between pairs of haploid genomes. The result provides a framework for interpreting PCA projections in terms of underlying processes, including migration, geographical isolation, and admixture. I also demonstrate a link between PCA and Wright's fst and show that SNP ascertainment has a largely simple and predictable effect on the projection of samples. Using examples from human genetics, I discuss the application of these results to empirical data and the implications for inference. PMID:19834557

Facilitating in vivo tumor localization by principal component analysis based on dynamic fluorescence molecular imaging

Science.gov (United States)

Gao, Yang; Chen, Maomao; Wu, Junyu; Zhou, Yuan; Cai, Chuangjian; Wang, Daliang; Luo, Jianwen

2017-09-01

Fluorescence molecular imaging has been used to target tumors in mice with xenograft tumors. However, tumor imaging is largely distorted by the aggregation of fluorescent probes in the liver. A principal component analysis (PCA)-based strategy was applied on the in vivo dynamic fluorescence imaging results of three mice with xenograft tumors to facilitate tumor imaging, with the help of a tumor-specific fluorescent probe. Tumor-relevant features were extracted from the original images by PCA and represented by the principal component (PC) maps. The second principal component (PC2) map represented the tumor-related features, and the first principal component (PC1) map retained the original pharmacokinetic profiles, especially of the liver. The distribution patterns of the PC2 map of the tumor-bearing mice were in good agreement with the actual tumor location. The tumor-to-liver ratio and contrast-to-noise ratio were significantly higher on the PC2 map than on the original images, thus distinguishing the tumor from its nearby fluorescence noise of liver. The results suggest that the PC2 map could serve as a bioimaging marker to facilitate in vivo tumor localization, and dynamic fluorescence molecular imaging with PCA could be a valuable tool for future studies of in vivo tumor metabolism and progression.

Principals' Collaborative Roles as Leaders for Learning

Science.gov (United States)

Kitchen, Margaret; Gray, Susan; Jeurissen, Maree

2016-01-01

This article draws on data from three multicultural New Zealand primary schools to reconceptualize principals' roles as leaders for learning. In doing so, the writers build on Sinnema and Robinson's (2012) article on goal setting in principal evaluation. Sinnema and Robinson found that even principals hand-picked for their experience fell short on…

Principals as Assessment Leaders in Rural Schools

Science.gov (United States)

Renihan, Patrick; Noonan, Brian

2012-01-01

This article reports a study of rural school principals' assessment leadership roles and the impact of rural context on their work. The study involved three focus groups of principals serving small rural schools of varied size and grade configuration in three systems. Principals viewed assessment as a matter of teacher accountability and as a…

Principal minors and rhombus tilings

International Nuclear Information System (INIS)

Kenyon, Richard; Pemantle, Robin

2014-01-01

The algebraic relations between the principal minors of a generic n × n matrix are somewhat mysterious, see e.g. Lin and Sturmfels (2009 J. Algebra 322 4121–31). We show, however, that by adding in certain almost principal minors, the ideal of relations is generated by translations of a single relation, the so-called hexahedron relation, which is a composition of six cluster mutations. We give in particular a Laurent-polynomial parameterization of the space of n × n matrices, whose parameters consist of certain principal and almost principal minors. The parameters naturally live on vertices and faces of the tiles in a rhombus tiling of a convex 2n-gon. A matrix is associated to an equivalence class of tilings, all related to each other by Yang–Baxter-like transformations. By specializing the initial data we can similarly parameterize the space of Hermitian symmetric matrices over R,C or H the quaternions. Moreover by further specialization we can parametrize the space of positive definite matrices over these rings. This article is part of a special issue of Journal of Physics A: Mathematical and Theoretical devoted to ‘Cluster algebras mathematical physics’. (paper)

Novel Therapeutic Target for the Treatment of Lupus

Science.gov (United States)

2014-09-01

AWARD NUMBER: W81XWH-12-1-0205 TITLE: Novel Therapeutic Target for the Treatment of Lupus PRINCIPAL INVESTIGATOR: Lisa Laury-Kleintop...SUBTITLE 5a. CONTRACT NUMBER Novel Therapeutic Target for the Treatment of Lupus 5b. GRANT NUMBER W81XWH-12-1-0205 5c. PROGRAM ELEMENT NUMBER 6...Systemic lupus erythematosus, autoantibodies. 16. SECURITY CLASSIFICATION OF: 17. LIMITATION OF ABSTRACT 18. NUMBER OF PAGES 7 19a. NAME OF

Statewide Data on Supply and Demand of Principals after Policy Changes to Principal Preparation in Illinois

Science.gov (United States)

Haller, Alicia; Hunt, Erika

2016-01-01

Research has demonstrated that principals have a powerful impact on school improvement and student learning. Principals play a vital role in recruiting, developing, and retaining effective teachers; creating a school-wide culture of learning; and implementing a continuous improvement plan aimed at increasing student achievement. Leithwood, Louis,…

Compound Structure-Independent Activity Prediction in High-Dimensional Target Space.

Science.gov (United States)

Balfer, Jenny; Hu, Ye; Bajorath, Jürgen

2014-08-01

Profiling of compound libraries against arrays of targets has become an important approach in pharmaceutical research. The prediction of multi-target compound activities also represents an attractive task for machine learning with potential for drug discovery applications. Herein, we have explored activity prediction in high-dimensional target space. Different types of models were derived to predict multi-target activities. The models included naïve Bayesian (NB) and support vector machine (SVM) classifiers based upon compound structure information and NB models derived on the basis of activity profiles, without considering compound structure. Because the latter approach can be applied to incomplete training data and principally depends on the feature independence assumption, SVM modeling was not applicable in this case. Furthermore, iterative hybrid NB models making use of both activity profiles and compound structure information were built. In high-dimensional target space, NB models utilizing activity profile data were found to yield more accurate activity predictions than structure-based NB and SVM models or hybrid models. An in-depth analysis of activity profile-based models revealed the presence of correlation effects across different targets and rationalized prediction accuracy. Taken together, the results indicate that activity profile information can be effectively used to predict the activity of test compounds against novel targets. © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

The Deputy Principal Instructional Leadership Role and Professional Learning: Perceptions of Secondary Principals, Deputies and Teachers

Science.gov (United States)

Leaf, Ann; Odhiambo, George

2017-01-01

Purpose: The purpose of this paper is to report on a study examining the perceptions of secondary principals, deputies and teachers, of deputy principal (DP) instructional leadership (IL), as well as deputies' professional learning (PL) needs. Framed within an interpretivist approach, the specific objectives of this study were: to explore the…

Principals' Perceptions of School Public Relations

Science.gov (United States)

Morris, Robert C.; Chan, Tak Cheung; Patterson, Judith

2009-01-01

This study was designed to investigate school principals' perceptions on school public relations in five areas: community demographics, parental involvement, internal and external communications, school council issues, and community resources. Findings indicated that principals' concerns were as follows: rapid population growth, change of…

The Principal's Roles in Building Capacity for Change

Science.gov (United States)

Butler, Sara Griffiths

2017-01-01

This qualitative dissertation explores how the principal's leadership roles build capacity for change and how chaos theory contributes to this understanding. The roles studied include distributive leadership, moral leadership, social justice leadership, democratic leadership, and instructional leadership. The tenets of chaos theory examined…

Public Relations for Principals. "A Guidebook for the Pennsylvania Administrator."

Science.gov (United States)

Pennsylvania School Boards Association, Inc., Harrisburg.

This report discusses what makes news, what people want to read, and how to write news releases or other informative bulletins and brochures. Also included are a description of principal-reporter-editor relations, some layout and typography data, and photography instructions. (JF)

Principal-vector-directed fringe-tracking technique.

Science.gov (United States)

Zhang, Zhihui; Guo, Hongwei

2014-11-01

Fringe tracking is one of the most straightforward techniques for analyzing a single fringe pattern. This work presents a principal-vector-directed fringe-tracking technique. It uses Gaussian derivatives for estimating fringe gradients and uses hysteresis thresholding for segmenting singular points, thus improving the principal component analysis method. Using it allows us to estimate the principal vectors of fringes from a pattern with high noise. The fringe-tracking procedure is directed by these principal vectors, so that erroneous results induced by noise and other error-inducing factors are avoided. At the same time, the singular point regions of the fringe pattern are identified automatically. Using them allows us to determine paths through which the "seed" point for each fringe skeleton is easy to find, thus alleviating the computational burden in processing the fringe pattern. The results of a numerical simulation and experiment demonstrate this method to be valid.

The Principal and "The Prince": Machiavelli and School Leadership.

Science.gov (United States)

English, Fenwick W.

1992-01-01

Because most people will resist law and reason (government), power must be rendered in someone else's name to make ruling palatable. Executives, including principals, represent the law. To enforce a given law, executives must often exceed their base of authority to act decisively--despite recent rhetoric about staff empowerment and site-based…

Whose Perception of Principal Instructional Leadership? Principal-Teacher Perceptual (Dis)agreement and Its Influence on Teacher Collaboration

Science.gov (United States)

Park, Joo-Ho; Ham, Seung-Hwan

2016-01-01

This study examines teacher collaboration across three Asia-Pacific countries (Australia, Malaysia, and South Korea), focusing on the possibility that principal-teacher perceptual disagreement regarding principal instructional leadership performance may impede progress toward a school organizational condition conducive to collaborative teacher…

NIF target fill, transport and insertion cryostat

International Nuclear Information System (INIS)

Warren, R.

1994-01-01

A cryostat to support the fielding of a cryogenic target within the NIF is described. The present design is predicated upon fuel layer symmetry being achieved with the β layering process and modifications needed for other fuel symmetrization processes are discussed. These include the vertically differentially heated capsule with a uniform liquid layer stabilized by a surface tension gradient, foam supported liquid layers and solid D 2 or HD layers symmetrized by bulk irradiation from a laser source. The cold sinks to be incorporated in these techniques could, in principal, be cooled with the high pressure helium envisioned for the heat sink rings of the present design. Supplementary laser access would be provided for differential heating of the capsule for surface tension gradient stabilization of a liquid layer or bulk heating of a solid layer. The cryostat in each of these cases would look substantially the same as in the present case with the only significant differences being in the details of the design in the immediate vicinity of the target

Aberrant Recapitulation of Developmental Program: Novel Target in Scleroderma

Science.gov (United States)

2015-12-01

AWARD NUMBER: W81XWH-12-1-0472 TITLE: “Aberrant Recapitulation of Developmental Program: Novel Target in Scleroderma ” PRINCIPAL INVESTIGATOR...SUBTITLE Aberrant Recapitulation of Developmental Program: Novel Target in Scleroderma 5a. CONTRACT NUMBER W81XWH-12-1-0472 5b. GRANT NUMBER 5c. PROGRAM...SPONSOR/MONITOR’S REPORT NUMBER(S) 12. DISTRIBUTION / AVAILABILITY STATEMENT 13. SUPPLEMENTARY NOTES 14. ABSTRACT Fibrosis in scleroderma is associated

New pulser for principal PO power

International Nuclear Information System (INIS)

Coudert, G.

1984-01-01

The pulser of the principal power of the PS is the unit that makes it possible to generate the reference function of the voltage of the principal magnet. This function depends on time and on the magnetic field of the magnet. It also generates various synchronization and reference pulses

An Examination of Principal Job Satisfaction

Science.gov (United States)

Pengilly, Michelle M.

2010-01-01

As education continues to succumb to deficits in budgets and increasingly high levels of student performance to meet the federal and state mandates, the quest to sustain and retain successful principals is imperative. The National Association of School Boards (1999) portrays effective principals as "linchpins" of school improvement and…

Social Media Strategies for School Principals

Science.gov (United States)

Cox, Dan; McLeod, Scott

2014-01-01

The purpose of this qualitative study was to describe, analyze, and interpret the experiences of school principals who use multiple social media tools with stakeholders as part of their comprehensive communications practices. Additionally, it examined why school principals have chosen to communicate with their stakeholders through social media.…

[School principals--too ill for healthy schools?].

Science.gov (United States)

Weber, A; Weltle, D; Lederer, P

2004-03-01

School principals on the one hand play an important role in maintaining the performance and health of teachers, but on the other hand often feel over-burdened themselves and suffer from illnesses which not only impair their health-promoting function, but also lead to limitations in their fitness for the occupation. The aim of our study was therefore, using objective parameters and larger numbers of cases, to obtain a differentiated insight into the type and extent of morbidity spectrum and the health-related early retirement of school principals. In a prospective total assessment (the whole of Bavaria in the period 1997-1999), all the reports about the premature unfitness for work of school directors were evaluated. The analysis included for example socio-demographic/occupational factors, diagnoses, assessment of performance and rehabilitation. The answers given in a standardised, anonymous questionnaire provided the database. Evaluation was carried out by means of descriptive statistics. The median age of the 408 school principals included in the evaluation (heads and vice-heads, 30% of whom were women) was 58 (min: 41 years old, max: 64 years old). The most frequent workplaces were primary schools (38%) and secondary schools (25%). 84% (n=342) of the headmasters were assessed to be unfit for work. The main reasons for early retirement were psychic/psychosomatic illnesses (F-ICD 10) which made up 45% of the cases. The relative frequency was higher in women than in men. Depressive disorders and exhaustion syndromes (burnout) dominated among the psychiatric diagnoses (proportion: 57%). The most frequent somatic diseases were cardio-vascular diseases (I-ICD10) in 19% of cases, then muscular/skeletal diseases (M-ICD10) in 10% and malignant tumours (C-ICD 10) in 9% of cases. Cardio-vascular diseases, in particular arterial hypertonia and ischaemic heart disease, were, in addition, found in headmasters significantly more frequently than in teachers without a leadership

The Interdependence of Principal School Leadership and Student Achievement

Science.gov (United States)

Soehner, David; Ryan, Thomas

2011-01-01

This review illuminated principal school leadership as a variable that impacted achievement. The principal as school leader and manager was explored because these roles were thought to impact student achievement both directly and indirectly. Specific principal leadership behaviors and principal effectiveness were explored as variables potentially…

District Leadership for Effective Principal Evaluation and Support

Science.gov (United States)

Kimball, Steven M.; Arrigoni, Jessica; Clifford, Matthew; Yoder, Maureen; Milanowski, Anthony

2015-01-01

Research demonstrating principals' impact on student learning outcomes has fueled the shift from principals as facilities managers to an emphasis on instructional leadership (Hallinger & Heck, 1996; Leithwood, Louis, Anderson, & Wahlstrom, 2004; Marzano, Waters, & McNulty, 2005). Principals are under increasing pressure to carry out…

School Restructuring and the Dilemmas of Principals' Work.

Science.gov (United States)

Wildy, Helen; Louden, William

2000-01-01

The complexity of principals' work may be characterized according to three dilemmas: accountability, autonomy, and efficiency. Narrative vignettes of 74 Australian principals revealed that principals were fair and inclusive. When faced with restructuring dilemmas, however, they favored strong over shared leadership, efficiency over collaboration,…

Do Principals Fire the Worst Teachers?

Science.gov (United States)

Jacob, Brian A.

2011-01-01

This article takes advantage of a unique policy change to examine how principals make decisions regarding teacher dismissal. In 2004, the Chicago Public Schools (CPS) and Chicago Teachers Union signed a new collective bargaining agreement that gave principals the flexibility to dismiss probationary teachers for any reason and without the…

Revising the Role of Principal Supervisor

Science.gov (United States)

Saltzman, Amy

2016-01-01

In Washington, D.C., and Tulsa, Okla., districts whose efforts are supported by the Wallace Foundation, principal supervisors concentrate on bolstering their principals' work to improve instruction, as opposed to focusing on the managerial or operational aspects of running a school. Supervisors oversee fewer schools, which enables them to provide…

The Principal's Guide to Grant Success.

Science.gov (United States)

Bauer, David G.

This book provides principals of public and private elementary and middle schools with a step-by-step approach for developing a system that empowers faculty, staff, and the school community in attracting grant funds. Following the introduction, chapter 1 discusses the principal's role in supporting grantseeking. Chapter 2 describes how to…

Principals, agents and research programmes

OpenAIRE

Elizabeth Shove

2003-01-01

Research programmes appear to represent one of the more powerful instruments through which research funders (principals) steer and shape what researchers (agents) do. The fact that agents navigate between different sources and styles of programme funding and that they use programmes to their own ends is readily accommodated within principal-agent theory with the help of concepts such as shirking and defection. Taking a different route, I use three examples of research programming (by the UK, ...

Emissions and targets of greenhouse gases not included in the Emission Trading System 2013-2020

Energy Technology Data Exchange (ETDEWEB)

Verdonk, M.

2011-06-15

This report evaluates the European Commission's (EC) proposal to calculate Member States' targets for emissions not included in the Emission Trading System (ETS) (as announced in the so-called Effort Sharing Decision). The calculation procedures and data sources proposed by the EC have been used for calculating non-ETS emission targets for the Netherlands, for the years from 2013 to 2020. In order to compare results, an alternative approach also was introduced and evaluated. In this approach more transparent data sources were used. Furthermore, the report updates the emission forecast of non-ETS emission levels in the Netherlands, for 2020, and evaluates the consequences of excluding uncertainties related to monitoring from the (updated) emission forecast. It is concluded that, for the Netherlands, the non-ETS emission caps as proposed by the EC would result in an emission cap of 105 Mt CO2 equivalent by 2020. This is higher than in the alternative approach, which would result in a cap of 103 Mt CO2 equivalents. The difference is explained by the different data sources that were used. A drawback of the data sources used in the EC proposal is the lack of transparency of part of the data, which resulted in an additional uncertainty as not all issues could be verified. However, other Member States may not have similar data sources available, in case the EC decides to adopt the alternative approach. The calculated emission caps are to be considered as estimates based on the most recent (but sometimes uncertain) statistics. The EC will determine the definite caps by the end of 2012. Based on a 2010 forecast, and including both an updated division of emissions into ETS and non-ETS emissions and a revised methodology for calculating nitrous oxide emissions, we estimate that non-ETS emissions in the Netherlands would be 104 Mt CO2 equivalents by 2020, with an uncertainty range of between 96 and 112 Mt CO2 equivalents. It is our conclusion that non-ETS emission

Negligence--When Is the Principal Liable? A Legal Memorandum.

Science.gov (United States)

Stern, Ralph D., Ed.

Negligence, a tort liability, is defined, discussed, and reviewed in relation to several court decisions involving school principals. The history of liability suits against school principals suggests that a reasonable, prudent principal can avoid legal problems. Ten guidelines are presented to assist principals in avoiding charges of negligence.…

Control room philosophy: Principles of control room design and control room work; Kontrollrumsfilosofi: Principer foer kontrollrumsutformning och kontrollrumsarbete

Energy Technology Data Exchange (ETDEWEB)

Skriver, Jan; Ramberg, Jasmine; Allwin, Pernilla [Scandpower Risk Management AB, Uppsala (Sweden)

2006-01-15

In order to provide insights for improvement of work in control rooms several factors have to be considered. Knowledge of principles including control room philosophies will guide the recommended improvements. In addition to knowledge about specific principles an advantage for an organization can be an understanding of similarities and policies used in other high risk industry. The report has been developed on the basis of a document analysis of international standards and other guiding documents. (NUREG 0711, ISO 11064, ISO 6385, IEC 60964). In addition to the document analysis which has strived to compare the documents to see similarities in important principals, experience from working with control room design, modifications and evaluations in other high risk industries has pervaded the report. Important principles have been identified which are recommended to be included in a control room philosophy. Many of these are similar to the principles identified in the international standards. An additional principal which is regarded as important is the utilization of Key Performance Indicators (KPI) which can be used as a measure to target preventative means. Further more it is critical that the control room philosophy is easy to access and comprehend for all users. One of the challenges that remain after having developed a control room philosophy is how to utilize it in the daily work situation. It is vital that the document remains as a living document, guiding the continual improvement of the control room in the various life cycle stages.

The Principal and the Law. Elementary Principal Series No. 7.

Science.gov (United States)

Doverspike, David E.; Cone, W. Henry

Developments over the past 25 years in school-related legal issues in elementary schools have significantly changed the principal's role. In 1975, a decision of the U.S. Supreme Court established three due-process guidelines for short-term suspension. The decision requires student notification of charges, explanation of evidence, and an informal…

Should Principals Know More about Law?

Science.gov (United States)

Doctor, Tyrus L.

2013-01-01

Educational law is a critical piece of the education conundrum. Principals reference law books on a daily basis in order to address the wide range of complex problems in the school system. A principal's knowledge of law issues and legal decision-making are essential to provide effective feedback for a successful school.

Knowledge and attitudes about mental disorders among principals of adult education schools.

Science.gov (United States)

Ponizovsky, Alexander; Grinshpoon, Alexander; Sasson, Rachel; Baidani-Auerbach, Alona; Ben Eliezer, Deborah; Shershevsky, Yechiel

2003-01-01

The Ministry of Health is stepping up its efforts to both reduce the inpatient psychiatric population and enable former inmates to become fully reintegrated into society. The latter aim includes the provision of formal education for those with mental disorders who did not complete a full cycle of schooling. Stigma and discrimination at school may lead to the failure of this program. To explore the knowledge and attitudes of the principals of schools for adult education towards mental illness and persons with mental disorders. Almost all countrywide school principals (93.8%, n = 76) were interviewed by telephone using a short questionnaire of 16 items tapping their knowledge and attitudes. Frequency distributions, Chi-square and t-tests were used to analyze the data. The school principals were able to mention a fewer number of mental disorders in contrast to medical conditions, used as reference criteria. They recognized psychosis but not depression as a mental disorder. Their attitudes revealed an ambivalent approach to the person with a mental disorder, including those that are students. Higher level of academic education was associated with positive attitudes, while personal familiarity with a mentally disturbed person was slightly associated with more positive school-related attitudes. The results suggest a "case for action": programs to enhance mental health knowledge and foster more positive attitudes among school principals would seem to be needed. This would better assure the integration of the former inpatient into the adult education system.

Lung Squamous Cell Carcinoma Stem Cells as Immunotherapy Targets

Science.gov (United States)

2017-08-01

AWARD NUMBER: W81XWH-16-1-0260 TITLE: Lung Squamous Cell Carcinoma Stem Cells as Immunotherapy Targets PRINCIPAL INVESTIGATOR: Carla Kim... Cell Carcinoma Stem Cells as Immunotherapy Targets 5a. CONTRACT NUMBER 5b. GRANT NUMBER W81XWH-16-1-0260 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S...SUPPLEMENTARY NOTES 14. ABSTRACT Lung squamous cell carcinoma (SCC) is the second most common type of lung cancer, and immunotherapy is a promising new

Principal Ports and Facilities

Data.gov (United States)

California Natural Resource Agency — The Principal Port file contains USACE port codes, geographic locations (longitude, latitude), names, and commodity tonnage summaries (total tons, domestic, foreign,...

Principal Ports and Facilities

Data.gov (United States)

California Department of Resources — The Principal Port file contains USACE port codes, geographic locations (longitude, latitude), names, and commodity tonnage summaries (total tons, domestic, foreign,...

Promoting principals' managerial involvement in instructional improvement.

Science.gov (United States)

Gillat, A

1994-01-01

Studies of school leadership suggest that visiting classrooms, emphasizing achievement and training, and supporting teachers are important indicators of the effectiveness of school principals. The utility of a behavior-analytic program to support the enhancement of these behaviors in 2 school principals and the impact of their involvement upon teachers' and students' performances in three classes were examined in two experiments, one at an elementary school and another at a secondary school. Treatment conditions consisted of helping the principal or teacher to schedule his or her time and to use goal setting, feedback, and praise. A withdrawal design (Experiment 1) and a multiple baseline across classrooms (Experiment 2) showed that the principal's and teacher's rates of praise, feedback, and goal setting increased during the intervention, and were associated with improvements in the academic performance of the students. In the future, school psychologists might analyze the impact of involving themselves in supporting the principal's involvement in improving students' and teachers' performances or in playing a similar leadership role themselves.

Primary School Principals' Self-Monitoring Skills

Science.gov (United States)

Konan, Necdet

2015-01-01

The aim of the present study is to identify primary school principals' self-monitoring skills. The study adopted the general survey model and its population comprised primary school principals serving in the city of Diyarbakir, Turkey, while 292 of these constituted the sample. Self-Monitoring Scale was used as the data collection instrument. In…

How Not to Prepare School Principals

Science.gov (United States)

Davis, Stephen H.; Leon, Ronald J.

2011-01-01

Instead of focusing on how principals should be trained, an contrarian view is offered, grounded upon theoretical perspectives of experiential learning, and in particular, upon the theory of andragogy. A brief parable of the DoNoHarm School of Medicine is used as a descriptive analog for many principal preparation programs in America. The…

High School Principals and School Reform: Lessons Learned from a Statewide Study of Project Re:Learning.

Science.gov (United States)

Anderson, Lorin W.; Shirley, J. Robert

1995-01-01

Summarizes a study examining the high school principal's role in providing the leadership needed to explore and implement Project Re:Learning. The 4-phase study initially included 15 schools and involved questionnaires, interviews, and shadowing. Identifies six types of administrators: the absent administrator, the pawn, the pragmatic principal,…

Evaluating the Effectiveness of Traditional and Alternative Principal Preparation Programs

Science.gov (United States)

Pannell, Summer; Peltier-Glaze, Bernnell M.; Haynes, Ingrid; Davis, Delilah; Skelton, Carrie

2015-01-01

This study sought to determine the effectiveness on increasing student achievement of principals trained in a traditional principal preparation program and those trained in an alternate route principal preparation program within the same Mississippi university. Sixty-six Mississippi principals and assistant principals participated in the study. Of…

Principal Turnover: Upheaval and Uncertainty in Charter Schools?

Science.gov (United States)

Ni, Yongmei; Sun, Min; Rorrer, Andrea

2015-01-01

Purpose: Informed by literature on labor market and school choice, this study aims to examine the dynamics of principal career movements in charter schools by comparing principal turnover rates and patterns between charter schools and traditional public schools. Research Methods/Approach: This study uses longitudinal data on Utah principals and…

Looked after or Left Behind: The Effectiveness of Principal Preparation Programs as Perceived by Generation Y Principals

Science.gov (United States)

Sledge, Chandra

2013-01-01

This research study intended to discover the perceptions of 10 Illinois Generation Y novice high school principals pertaining to the effectiveness of their principal preparation programs in terms of how well it prepared them to lead in the first three years of their principalship, and what subsequent professional development they deemed necessary…

Stepping stones: Principal career paths and school outcomes.

Science.gov (United States)

Béteille, Tara; Kalogrides, Demetra; Loeb, Susanna

2012-07-01

More than one out of every five principals leaves their school each year. In some cases, these career changes are driven by the choices of district leadership. In other cases, principals initiate the move, often demonstrating preferences to work in schools with higher achieving students from more advantaged socioeconomic backgrounds. Principals often use schools with many poor or low-achieving students as stepping stones to what they view as more desirable assignments. We use longitudinal data from one large urban school district to study the relationship between principal turnover and school outcomes. We find that principal turnover is, on average, detrimental to school performance. Frequent turnover of school leadership results in lower teacher retention and lower student achievement gains. Leadership changes are particularly harmful for high poverty schools, low-achieving schools, and schools with many inexperienced teachers. These schools not only suffer from high rates of principal turnover but are also unable to attract experienced successors. The negative effect of leadership changes can be mitigated when vacancies are filled by individuals with prior experience leading other schools. However, the majority of new principals in high poverty and low-performing schools lack prior leadership experience and leave when more attractive positions become available in other schools. Copyright © 2012 Elsevier Inc. All rights reserved.

The Relationship between Emotional Intelligence of Principals and the Overall Organizational Climate of Public Elementary Schools

Science.gov (United States)

Juma, Dalal Sabri

2013-01-01

In this study the researcher examined the influence between a principal's self-perceived emotional intelligence and the overall organizational climate of one public elementary school as perceived by the principal's followers. These followers included teaching and non-teaching staff. It was not known how self-perceived emotional intelligence of a…

School Library Policy and Legal Opinions of Texas Public School Principals and Certified Librarians

Directory of Open Access Journals (Sweden)

Andrew Shupala

2006-09-01

Full Text Available This study involved a survey of the attitudes of Texas public school principals and certified librarians, perceptions andexperiences with regard to school library policy for media selection, and procedures for responding to complaints againstlibrary media. Analysis of the data included a methodology of mixed-methods explanatory design. Selection of the principalsand certified librarians was proportionate and stratified according to the state's 20 Education Service Centerregions. Of the 1,036 independent school districts that employed the state population of 10,014 principals and certifiedlibrarians, 275 independent school districts (26.5 percent allowed participation in the survey. Although random samplingof the state population had not been possible, the demographic and employment characteristics of the study samplewere comparable to those of the state population. Two key findings were (a that the legal opinions of principals andcertified librarians were useful predictors of their opinions of library media selection policy and complaint proceduresand (b that the principals' appreciation of selection policy and complaint procedures sometimes differed from the librarians'because of the principals' different legal perspective of library selection policy and complaint procedures.

Aquaporin-2 membrane targeting

DEFF Research Database (Denmark)

Olesen, Emma T B; Fenton, Robert A

2017-01-01

The targeting of the water channel aquaporin-2 (AQP2) to the apical plasma membrane of kidney collecting duct principal cells is regulated mainly by the antidiuretic peptide hormone arginine vasopressin (AVP). This process is of crucial importance for the maintenance of body water homeostasis...... of aquaporin-2 (AQP2) to the apical plasma membrane of collecting duct (CD) principal cells (10, 20). This process is mainly regulated by the actions of AVP on the type 2 AVP receptor (V2R), although the V1a receptor may also play a minor role (26). The V2R is classified within the group of 7-transmembrane....... For example, 1) stimulation with the nonspecific AC activator forskolin increases AQP2 membrane accumulation in a mouse cortical collecting duct cell line [e.g., Norregaard et al. (16)]; 2) cAMP increases CD water permeability (15); 3) the cAMP-activated protein kinase A (PKA) can phosphorylate AQP2 on its...

The High School Dropout Problem: Perspectives of Teachers and Principals

Science.gov (United States)

Bridgeland, John M.; Dilulio, John J., Jr.; Balfanz, Robert

2009-01-01

To better understand the views of teachers and administrators on the high school dropout problem, focus groups and nationally representative surveys were conducted of high school teachers and principals. A focus group of superintendents and school board members was also included. To help interpret the results, the authors convened a colloquium…

Surrogate Endpoint Evaluation: Principal Stratification Criteria and the Prentice Definition.

Science.gov (United States)

Gilbert, Peter B; Gabriel, Erin E; Huang, Ying; Chan, Ivan S F

2015-09-01

A common problem of interest within a randomized clinical trial is the evaluation of an inexpensive response endpoint as a valid surrogate endpoint for a clinical endpoint, where a chief purpose of a valid surrogate is to provide a way to make correct inferences on clinical treatment effects in future studies without needing to collect the clinical endpoint data. Within the principal stratification framework for addressing this problem based on data from a single randomized clinical efficacy trial, a variety of definitions and criteria for a good surrogate endpoint have been proposed, all based on or closely related to the "principal effects" or "causal effect predictiveness (CEP)" surface. We discuss CEP-based criteria for a useful surrogate endpoint, including (1) the meaning and relative importance of proposed criteria including average causal necessity (ACN), average causal sufficiency (ACS), and large clinical effect modification; (2) the relationship between these criteria and the Prentice definition of a valid surrogate endpoint; and (3) the relationship between these criteria and the consistency criterion (i.e., assurance against the "surrogate paradox"). This includes the result that ACN plus a strong version of ACS generally do not imply the Prentice definition nor the consistency criterion, but they do have these implications in special cases. Moreover, the converse does not hold except in a special case with a binary candidate surrogate. The results highlight that assumptions about the treatment effect on the clinical endpoint before the candidate surrogate is measured are influential for the ability to draw conclusions about the Prentice definition or consistency. In addition, we emphasize that in some scenarios that occur commonly in practice, the principal strata sub-populations for inference are identifiable from the observable data, in which cases the principal stratification framework has relatively high utility for the purpose of effect

Surrogate Endpoint Evaluation: Principal Stratification Criteria and the Prentice Definition

Science.gov (United States)

Gilbert, Peter B.; Gabriel, Erin E.; Huang, Ying; Chan, Ivan S.F.

2015-01-01

A common problem of interest within a randomized clinical trial is the evaluation of an inexpensive response endpoint as a valid surrogate endpoint for a clinical endpoint, where a chief purpose of a valid surrogate is to provide a way to make correct inferences on clinical treatment effects in future studies without needing to collect the clinical endpoint data. Within the principal stratification framework for addressing this problem based on data from a single randomized clinical efficacy trial, a variety of definitions and criteria for a good surrogate endpoint have been proposed, all based on or closely related to the “principal effects” or “causal effect predictiveness (CEP)” surface. We discuss CEP-based criteria for a useful surrogate endpoint, including (1) the meaning and relative importance of proposed criteria including average causal necessity (ACN), average causal sufficiency (ACS), and large clinical effect modification; (2) the relationship between these criteria and the Prentice definition of a valid surrogate endpoint; and (3) the relationship between these criteria and the consistency criterion (i.e., assurance against the “surrogate paradox”). This includes the result that ACN plus a strong version of ACS generally do not imply the Prentice definition nor the consistency criterion, but they do have these implications in special cases. Moreover, the converse does not hold except in a special case with a binary candidate surrogate. The results highlight that assumptions about the treatment effect on the clinical endpoint before the candidate surrogate is measured are influential for the ability to draw conclusions about the Prentice definition or consistency. In addition, we emphasize that in some scenarios that occur commonly in practice, the principal strata sub-populations for inference are identifiable from the observable data, in which cases the principal stratification framework has relatively high utility for the purpose of

Targeting Cell Polarity Machinery to Exhaust Breast Cancer Stem Cells

Science.gov (United States)

2017-10-01

AWARD NUMBER: W81XWH-15-1-0644 TITLE: Targeting Cell Polarity Machinery to Exhaust Breast Cancer Stem Cells PRINCIPAL INVESTIGATOR: Chun-Ju...Targeting Cell Polarity Machinery to Exhaust Breast Cancer Stem Cells 5a. CONTRACT NUMBER 5b. GRANT NUMBER W81XWH-15-1-0644 5c. PROGRAM ELEMENT...Unlimited 13. SUPPLEMENTARY NOTES 14. ABSTRACT Cancer stem cells (CSCs), a cell population with acquired perpetuating self-renewal properties which

A Review of the Literature on Principal Turnover

Science.gov (United States)

Snodgrass Rangel, Virginia

2018-01-01

Among the many challenges facing public schools are high levels of principal turnover. Given the important role that principals play and are expected to play in the improvement process, concerns about principal turnover have resulted in a growing body of research on its causes and consequences. The purpose of this review is to take stock of what…

Aerobic Physical Activity and the Leadership of Principals

Science.gov (United States)

Kiser, Kari

2016-01-01

The purpose of this study was to explore if there was a connection between regular aerobic physical activity and the stress and energy levels of principals as they reported it. To begin the research, the current aerobic physical activity level of principals was discovered. Additionally, the energy and stress levels of the principals who do engage…

Looking to the 21st Century--Principals with Vision Needed To Make Schools Exciting Places of Learning.

Science.gov (United States)

Glines, Don E.

1987-01-01

If schools and their programs are to prepare youth for tommorrow's world, principals today must be "dreamers of the dreams," advises this educator. He provides a rationale for his imperatives, followed by specific steps that principals should take. Includes three pages of references. (Author/MD)

Surface analysis the principal techniques

CERN Document Server

Vickerman, John C

2009-01-01

This completely updated and revised second edition of Surface Analysis: The Principal Techniques, deals with the characterisation and understanding of the outer layers of substrates, how they react, look and function which are all of interest to surface scientists. Within this comprehensive text, experts in each analysis area introduce the theory and practice of the principal techniques that have shown themselves to be effective in both basic research and in applied surface analysis. Examples of analysis are provided to facilitate the understanding of this topic and to show readers how they c

Subjective performance evaluations and reciprocity in principal-agent relations

DEFF Research Database (Denmark)

Sebald, Alexander Christopher; Walzl, Markus

2014-01-01

. In contrast to existing models of reciprocity, we find that agents tend to sanction whenever the feedback of principals is below their subjective self-evaluations even if agents' pay-offs are independent of it. In turn, principals provide more positive feedback (relative to their actual performance assessment......We conduct a laboratory experiment with agents working on, and principals benefiting from, a real effort task in which the agents' performance can only be evaluated subjectively. Principals give subjective performance feedback to agents, and agents have an opportunity to sanction principals...... of the agent) if this does not affect their pay-off....

Role Perceptions and Job Stress among Special Education School Principals: Do They Differ from Principals of Regular Schools?

Science.gov (United States)

Gaziel, Haim Henry; Cohen-Azaria, Yael; Ermenc, Klara Skubic

2012-01-01

The objective of the present study was to compare principals' perceptions of their leadership roles in regular (Dovno, 1999) versus special education (Zaretzky, Faircloth & Moreau, 2005) schools, and how these perceptions affect feelings of job stress (Friedman, 2001; Margalit, 1999). We predicted that regular school principals would differ in…

Deformation quantization of principal fibre bundles

International Nuclear Information System (INIS)

Weiss, S.

2007-01-01

Deformation quantization is an algebraic but still geometrical way to define noncommutative spacetimes. In order to investigate corresponding gauge theories on such spaces, the geometrical formulation in terms of principal fibre bundles yields the appropriate framework. In this talk I will explain what should be understood by a deformation quantization of principal fibre bundles and how associated vector bundles arise in this context. (author)

Enhancing Natural Killer Cell Mediated Targeting and Responses to Myeloid Leukemias

Science.gov (United States)

2017-10-01

AWARD NUMBER: W81XWH-16-1-0380 TITLE: Enhancing Natural Killer Cell Mediated Targeting and Responses to Myeloid Leukemias PRINCIPAL...2017 4. TITLE AND SUBTITLE 5a. CONTRACT NUMBER Enhancing Natural Killer Cell Mediated Targeting and Responses to Myeloid Leukemias 5b. GRANT NUMBER...leukemias still have poor prognosis, particularly in the elderly, and require hematopoietic cell transplants to fully kill the tumor, which is both

Artful Dodges Principals Use to Beat Bureaucracy.

Science.gov (United States)

Ficklen, Ellen

1982-01-01

A study of Chicago (Illinois) principals revealed many ways principals practiced "creative insubordination"--avoiding following instructions but still getting things done. Among the dodges are deliberately missing deadlines, following orders literally, ignoring channels to procure teachers or materials, and using community members to…

Principal spectra describing magnetooptic permittivity tensor in cubic crystals

Energy Technology Data Exchange (ETDEWEB)

Hamrlová, Jana [Nanotechnology Centre, VSB – Technical University of Ostrava, listopadu 15, Ostrava, 708 33 Czech Republic (Czech Republic); IT4Innovations Centre, VSB – Technical University of Ostrava, listopadu 15, Ostrava, 708 33 Czech Republic (Czech Republic); Legut, Dominik [IT4Innovations Centre, VSB – Technical University of Ostrava, listopadu 15, Ostrava, 708 33 Czech Republic (Czech Republic); Veis, Martin [Faculty of Mathematics and Physics, Charles University, Ke Karlovu 3, Prague, 121 16 Czech Republic (Czech Republic); Pištora, Jaromír [Nanotechnology Centre, VSB – Technical University of Ostrava, listopadu 15, Ostrava, 708 33 Czech Republic (Czech Republic); Hamrle, Jaroslav, E-mail: jaroslav.hamrle@vsb.cz [IT4Innovations Centre, VSB – Technical University of Ostrava, listopadu 15, Ostrava, 708 33 Czech Republic (Czech Republic); Faculty of Mathematics and Physics, Charles University, Ke Karlovu 3, Prague, 121 16 Czech Republic (Czech Republic); Department of Physics, VSB – Technical University of Ostrava, 17. listopadu 15, Ostrava, 708 33 Czech Republic (Czech Republic)

2016-12-15

We provide unified phenomenological description of magnetooptic effects being linear and quadratic in magnetization. The description is based on few principal spectra, describing elements of permittivity tensor up to the second order in magnetization. Each permittivity tensor element for any magnetization direction and any sample surface orientation is simply determined by weighted summation of the principal spectra, where weights are given by crystallographic and magnetization orientations. The number of principal spectra depends on the symmetry of the crystal. In cubic crystals owning point symmetry we need only four principal spectra. Here, the principal spectra are expressed by ab initio calculations for bcc Fe, fcc Co and fcc Ni in optical range as well as in hard and soft x-ray energy range, i.e. at the 2p- and 3p-edges. We also express principal spectra analytically using modified Kubo formula.

Environmental forensic principals for sources allocation of polycyclic aromatic hydrocarbons

International Nuclear Information System (INIS)

O'Sullivan, G.; Martin, E.; Sandau, C.D.

2008-01-01

Polycyclic aromatic hydrocarbons (PAH) are organic compounds which include only carbon and hydrogen with a fused ring structure containing at least two six-sided benzene rings but may also contain additional fused rings that are not six-sided. The environmental forensic principals for sources allocation of PAHs were examined in this presentation. Specifically, the presentation addressed the structure and physiochemical properties of PAHs; sources and sinks; fate and behaviour; analytical techniques; conventional source identification techniques; and toxic equivalent fingerprinting. It presented a case study where residents had been allegedly exposed to dioxins, PAHs and metals released from a railroad tie treatment plant. The classification of PAHs is governed by thermodynamic properties such as biogenic, petrogenic, and pyrogenic properties. A number of techniques were completed, including chemical fingerprinting; molecular diagnostic ratios; cluster analysis; principal component analysis; and TEF fingerprinting. These techniques have shown that suspected impacted sites do not all share similar PAH signatures indicating the potential for various sources. Several sites shared similar signatures to background locations. tabs., figs

Targeted Radiation Therapy for Cancer Initiative

Science.gov (United States)

2017-11-01

AWARD NUMBER: W81XWH-08-2-0174 TITLE: Targeted Radiation Therapy for Cancer Initiative PRINCIPAL INVESTIGATOR: Dusten Macdonald, MD...for Cancer Initiative 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) Dusten Macdonald, MD 5d. PROJECT NUMBER...Cancer Initiative Final Report INTRODUCTION: The full potential of radiation therapy has not been realized due to the inability to locate and

Reel Principals: A Descriptive Content Analysis of the Images of School Principals Depicted in Movies from 1997-2009

Science.gov (United States)

Wolfrom, Katy J.

2010-01-01

According to Glanz's early research, school principals have been depicted as autocrats, bureaucrats, buffoons, and/or villains in movies from 1950 to 1996. The purpose of this study was to determine if these stereotypical characterizations of school principals have continued in films from 1997-2009, or if more favorable images have emerged that…

The DRE-Principal Partnership: Making It Work.

Science.gov (United States)

Davis, Barbara; Elliott, Karen

1995-01-01

Discusses the roles of the director of religious education (DRE) and the school principal at Catholic schools, viewing them as complimentary rather than competitive. Provides examples of positive cooperation between the principal and DRE at Most Pure Heart of Mary Parish, in Shelby, Ohio. (KP)

New Principals' Perspectives of Their Multifaceted Roles

Science.gov (United States)

Gentilucci, James L.; Denti, Lou; Guaglianone, Curtis L.

2013-01-01

This study utilizes Symbolic Interactionism to explore perspectives of neophyte principals. Findings explain how these perspectives are modified through complex interactions throughout the school year, and they also suggest preparation programs can help new principals most effectively by teaching "soft" skills such as active listening…

Leading Learning: First-Year Principals' Reflections on Instructional Leadership

Science.gov (United States)

O'Doherty, Ann; Ovando, Martha N.

2013-01-01

This qualitative study examined the instructional leadership perceptions of four first-year principals. Findings illuminate five themes drawn from the data: definitions of instructional leadership, challenges that first-year principals faced, how these principals addressed these challenges, how the novice principals plan to enact their…

ROMA: representation and quantification of module activity from target expression data

Directory of Open Access Journals (Sweden)

Loredana eMartignetti

2016-02-01

Full Text Available In many analysis of high-throughput data in systems biology, there is a need to quantify the activity of a set of genes in individual samples. A typical example is the case where it is necessary to estimate the activity of a transcription factor (which is often not directly measurable from the expression of its target genes. We present here ROMA (Representation and quantification Of Module Activities Java software, designed for fast and robust computation of the activity of gene sets (or modules with coordinated expression. ROMA activity quantification is based on the simplest uni-factor linear model of gene regulation that approximates the expression data of a gene set by its first principal component.The proposed algorithm implements novel functionalities: it provides several method modifications for principal components computation, including weighted, robust and centered methods; it distinguishes overdispersed modules (based on the variance explained by the first principal component and coordinated modules (based on the significance of the spectral gap; finally, it computes statistical significance of the estimated module overdispersion or coordination.ROMA can be applied in many contexts, from estimating differential activities of transcriptional factors to findingoverdispersed pathways in single-cell transcriptomics data. We describe here the principles of ROMA providing several practical examples of its use.ROMA source code is available at https://github.com/sysbio-curie/Roma.

Honouring Roles: The Story of a Principal and a Student

Directory of Open Access Journals (Sweden)

Jerome Cranston

2012-11-01

Full Text Available The importance of the teacher-student relationship in educational practice is well established, as is the idea of principal leadership in relationship to staff. Even though principal leadership is regarded as a factor in student success, the principal’s effect is usually assumed to take place via the teaching staff. There is an absence of research about the “lived experience” of direct principal-student relationships that shed lights on the ways in which these relationships play a role in student success and principal transformation. This paper presents two narratives written about a particular set of principal-student interactions experienced by the researcher (principal and participant (student.  The analysis uses a narrative inquiry approach to explore both the individual and collective meanings of this principal-student relationship. The stories and their derived meanings have the potential to enliven and  influence educational practice as they explore the subtleties of the principal-student relationship.

The Principal's Role in Site-Based Management.

Science.gov (United States)

Drury, William R.

1993-01-01

In existing school-based management models, the principal's role ranges from chairing the local council to being a coach/facilitator. With teachers and parents assuming greater control over governance, curriculum, and budgeting, paranoid principals may establish more formal bargaining relationships with district boards. Caution is advised, because…

Leadership Standards in Action: The School Principal as Servant-Leader

Science.gov (United States)

Brumley, Cade

2011-01-01

"Leadership Standards In Action: The School Principal as Servant-Leader" is a powerful resource for aspiring principals, practicing principals, district leadership, and university faculty. The book responsibly unpacks the metaphor of principal as servant leader to the school's people and purpose. As a framework, the six ISLLC Standards of…

Towards a leadership programme for primary school principals as instructional leaders

Directory of Open Access Journals (Sweden)

Parvathy Naidoo

2016-02-01

Full Text Available This study set out to explore primary school principals’ instructional leadership. The study addressed a key issue in the school improvement literature, pertaining to the curriculum leadership of principals. The literature is not entirely clear about which leadership characteristic is more likely to produce the most favourable outcomes in terms of improved learner outcomes, in other words, how the curriculum has been implemented and how leadership in this regard has been effected. The article argues that robust training and development in instructional leadership practices become necessary to support school leaders in this regard. In South Africa, based on numerous reports of poor learner outcomes in schools, we question whether principals possess the necessary skills required to lead and manage curriculum in schools. In this article, the views of five principals, who have completed the Advanced Certificate in Education: School Leadership and Management (ACESLM programme, are examined. Findings indicate that not all principals who participated in the study are fully conversant with their roles and responsibilities as instructional leaders. They mainly interpret their functions to be purely managerial and to be leaders and administrators of schools. Thus, whilst some understanding of instructional leadership was apparent in some of the principals’ responses, it is the authors’ views that ACESLM, as a leadership development programme, needs to be redesigned to include greater focus on instructional leadership.

Do Qualification, Experience and Age Matter for Principals Leadership Styles?

OpenAIRE

Muhammad Javed Sawati; Saeed Anwar; Muhammad Iqbal Majoka

2013-01-01

The main focus of present study was to find out the prevalent leadership styles of principals in government schools of Khyber Pakhtunkhwa and to find relationship of leadership styles with qualifications, age and experience of the principals. On the basis of analyzed data, four major leadership styles of the principals were identified as Eclectic, Democratic, Autocratic, and Free-rein. However, a small proportion of the principal had no dominant leadership style. This study shows that princip...

Novel GABA receptor pesticide targets.

Science.gov (United States)

Casida, John E; Durkin, Kathleen A

2015-06-01

The γ-aminobutyric acid (GABA) receptor has four distinct but overlapping and coupled targets of pesticide action importantly associated with little or no cross-resistance. The target sites are differentiated by binding assays with specific radioligands, resistant strains, site-directed mutagenesis and molecular modeling. Three of the targets are for non-competitive antagonists (NCAs) or channel blockers of widely varied chemotypes. The target of the first generation (20th century) NCAs differs between the larger or elongated compounds (NCA-IA) including many important insecticides of the past (cyclodienes and polychlorocycloalkanes) or present (fiproles) and the smaller or compact compounds (NCA-IB) highly toxic to mammals and known as cage convulsants, rodenticides or chemical threat agents. The target of greatest current interest is designated NCA-II for the second generation (21st century) of NCAs consisting for now of isoxazolines and meta-diamides. This new and uniquely different NCA-II site apparently differs enough between insects and mammals to confer selective toxicity. The fourth target is the avermectin site (AVE) for allosteric modulators of the chloride channel. NCA pesticides vary in molecular surface area and solvent accessible volume relative to avermectin with NCA-IBs at 20-22%, NCA-IAs at 40-45% and NCA-IIs at 57-60%. The same type of relationship relative to ligand-docked length is 27-43% for NCA-IBs, 63-71% for NCA-IAs and 85-105% for NCA-IIs. The four targets are compared by molecular modeling for the Drosophila melanogaster GABA-R. The principal sites of interaction are proposed to be: pore V1' and A2' for NCA-IB compounds; pore A2', L6' and T9' for NCA-IA compounds; pore T9' to S15' in proximity to M1/M3 subunit interface (or alternatively an interstitial site) for NCA-II compounds; and M1/M3, M2 interfaces for AVE. Understanding the relationships of these four binding sites is important in resistance management and in the discovery and use

Integrating Technology: The Principals' Role and Effect

Science.gov (United States)

Machado, Lucas J.; Chung, Chia-Jung

2015-01-01

There are many factors that influence technology integration in the classroom such as teacher willingness, availability of hardware, and professional development of staff. Taking into account these elements, this paper describes research on technology integration with a focus on principals' attitudes. The role of the principal in classroom…

Constructing principals' professional identities through life stories ...

African Journals Online (AJOL)

The Life History approach was used to collect data from six ... experience as the most significant leadership factors that influence principals' ... ranging from their entry into the teaching profession to their appointment as ..... teachers. I think I learnt from my principal to be strict but accommodating ..... Teachers College Press.

Women principals' reflections of curriculum management challenges ...

African Journals Online (AJOL)

This study reports the reflections of grade 6 rural primary principals in Mpumalanga province. A qualitative method of inquiry was used in this article, where data were collected using individual interviews with three principals and focus group discussions with the school management teams (SMTs) of three primary schools.

What Effective Principals Do to Improve Instruction and Increase Student Achievement

Science.gov (United States)

Turner, Elizabeth Anne

2013-01-01

The purposes of this mixed method study were to (a) Examine the relationships among principal effectiveness, principal instructional leadership, and student achievement; (b) examine the differences among principal effectiveness, principal instructional leadership and student achievement; and (c) investigate what effective principals do to improve…

Coaches' and Principals' Conceptualizations of the Roles of Elementary Mathematics Coaches

Science.gov (United States)

Salkind, Gwenanne M.

2010-01-01

Many schools employ coaches to support mathematics instruction and student learning. This research study investigated the roles of coaches from five school districts in Virginia. Participants included 125 elementary mathematics coaches and 59 principals. Results from cross-sectional surveys revealed that most coaches did not have a degree in…

Tumor Microenvironment Gene Signature as a Prognostic Classifier and Therapeutic Target

Science.gov (United States)

2016-06-01

AWARD NUMBER: W81XWH-14-1-0107 TITLE: Tumor Microenvironment Gene Signature as a Prognostic Classifier and Therapeutic Target PRINCIPAL...AND SUBTITLE Tumor Microenvironment Gene Signature as a 5a. CONTRACT NUMBER W81XWH-14-1-0107 Prognostic Classifier and Therapeutic Target 5b...gene signature that correlates with poor survival in ovarian cancer patients. We are refining this gene signature to develop biomarkers for the

Contemporary Challenges and Changes: Principals' Leadership Practices in Malaysia

Science.gov (United States)

Jones, Michelle; Adams, Donnie; Joo, Mabel Tan Hwee; Muniandy, Vasu; Perera, Corinne Jaqueline; Harris, Alma

2015-01-01

This article outlines the findings from a contemporary study of principals' leadership practices in Malaysia as part of the 7 System Leadership Study. Recent policy developments within Malaysia have increased principals' accountability and have underlined the importance of the role of the principals in transforming school performance and student…

3D face recognition with asymptotic cones based principal curvatures

KAUST Repository

Tang, Yinhang

2015-05-01

The classical curvatures of smooth surfaces (Gaussian, mean and principal curvatures) have been widely used in 3D face recognition (FR). However, facial surfaces resulting from 3D sensors are discrete meshes. In this paper, we present a general framework and define three principal curvatures on discrete surfaces for the purpose of 3D FR. These principal curvatures are derived from the construction of asymptotic cones associated to any Borel subset of the discrete surface. They describe the local geometry of the underlying mesh. First two of them correspond to the classical principal curvatures in the smooth case. We isolate the third principal curvature that carries out meaningful geometric shape information. The three principal curvatures in different Borel subsets scales give multi-scale local facial surface descriptors. We combine the proposed principal curvatures with the LNP-based facial descriptor and SRC for recognition. The identification and verification experiments demonstrate the practicability and accuracy of the third principal curvature and the fusion of multi-scale Borel subset descriptors on 3D face from FRGC v2.0.

3D face recognition with asymptotic cones based principal curvatures

KAUST Repository

Tang, Yinhang; Sun, Xiang; Huang, Di; Morvan, Jean-Marie; Wang, Yunhong; Chen, Liming

2015-01-01

The classical curvatures of smooth surfaces (Gaussian, mean and principal curvatures) have been widely used in 3D face recognition (FR). However, facial surfaces resulting from 3D sensors are discrete meshes. In this paper, we present a general framework and define three principal curvatures on discrete surfaces for the purpose of 3D FR. These principal curvatures are derived from the construction of asymptotic cones associated to any Borel subset of the discrete surface. They describe the local geometry of the underlying mesh. First two of them correspond to the classical principal curvatures in the smooth case. We isolate the third principal curvature that carries out meaningful geometric shape information. The three principal curvatures in different Borel subsets scales give multi-scale local facial surface descriptors. We combine the proposed principal curvatures with the LNP-based facial descriptor and SRC for recognition. The identification and verification experiments demonstrate the practicability and accuracy of the third principal curvature and the fusion of multi-scale Borel subset descriptors on 3D face from FRGC v2.0.

Principal bundles the classical case

CERN Document Server

Sontz, Stephen Bruce

2015-01-01

This introductory graduate level text provides a relatively quick path to a special topic in classical differential geometry: principal bundles.  While the topic of principal bundles in differential geometry has become classic, even standard, material in the modern graduate mathematics curriculum, the unique approach taken in this text presents the material in a way that is intuitive for both students of mathematics and of physics. The goal of this book is to present important, modern geometric ideas in a form readily accessible to students and researchers in both the physics and mathematics communities, providing each with an understanding and appreciation of the language and ideas of the other.

Incentives Research for Enterprises to Participate in VEP in the Multitask Principal-Agent Model

Directory of Open Access Journals (Sweden)

Mo Sha

2015-01-01

Full Text Available As a comprehensive environmental management system with a higher statutory environmental standard, Voluntary Environmental Program has become a trend of international environmental policy and the essence of it is a multi-agency task, in which government (principal entrust enterprise (proxy develop eco- nomic in the context of protecting the environment. Moreover, government is in a dominant position in the ef- fective implementation of voluntary environmental program, and their incentive to set different targets, under the voluntary environmental program, play a key role for the effective implementation of voluntary environ- mental program.

Taking a Distributed Perspective to the School Principal's Workday

Science.gov (United States)

Spillane, James P.; Camburn, Eric M.; Pareja, Amber Stitziel

2007-01-01

Focusing on the school principal's day-to-day work, we examine who leads curriculum and instruction- and administration-related activities when the school principal is not leading but participating in the activity. We also explore the prevalence of coperformance of management and leadership activities in the school principal's workday. Looking…

Principal Preparation in Special Education: Building an Inclusive Culture

Science.gov (United States)

Hofreiter, Deborah

2017-01-01

The importance of principal preparation in special education has increased since the Education for All Handicapped Children Act was passed in 1975. There are significant financial reasons for preparing principals in the area of special education. Recent research also shows that all children learn better in an inclusive environment. Principals who…

Urban School Principals and Their Role as Multicultural Leaders

Science.gov (United States)

Gardiner, Mary E.; Enomoto, Ernestine K.

2006-01-01

This study focuses on the role of urban school principals as multicultural leaders. Using cross-case analysis, the authors describe what 6 practicing principals do in regard to multicultural leadership. The findings suggest that although multicultural preparation was lacking for these principals, some did engage in work that promoted diversity in…

Principals: Human Capital Managers at Every School

Science.gov (United States)

Kimball, Steven M.

2011-01-01

Being a principal is more than just being an instructional leader. Principals also must manage their schools' teaching talent in a strategic way so that it is linked to school instructional improvement strategies, to the competencies needed to enact the strategies, and to success in boosting student learning. Teacher acquisition and performance…

25 CFR 20.308 - What does earned income include?

Science.gov (United States)

2010-04-01

... self-employment, total profit from a business enterprise (i.e., gross receipts less expenses incurred in producing the goods or services). Business expenses do not include depreciation, personal business and entertainment expenses, personal transportation, capital equipment purchases, or principal...

Navigating the Shift to Intensive Principal Preparation in Illinois: Policy Brief

Science.gov (United States)

White, Bradford R.; Pareja, Amber Stitziel; Hart, Holly; Huynh, Michelle Hanh; Klostermann, Brenda K.; Holt, Janet K.

2016-01-01

In 2010, Illinois became one of the first states to legislatively require a complete redesign of all its principal preparation programs, with the goal of advancing statewide school improvement through strengthening school leadership. This effort was ambitious and sweeping, calling for radical shifts in previous practice, including: (1) A targeted…

The Effects of Reform in Principal Selection on Leadership Behavior of General and Vocational High School Principals in Taiwan

Science.gov (United States)

Hsiao, Hsi-Chi; Lee, Ming-Chao; Tu, Ya-Ling

2013-01-01

Deregulation has formed the primary core of education reform in Taiwan in the past decade. The principal selection system was one of the specific recommendations in the deregulation of education. The method of designation of senior high school principals has changed from being "appointed" to being "selected." The issue as to…

Targeting Neutrophil Protease-Mediated Degradation of Tsp-1 to Induce Metastatic Dormancy

Science.gov (United States)

2017-10-01

AWARD NUMBER: W81XWH-16-1-0615 TITLE: Targeting Neutrophil Protease-Mediated Degradation of Tsp-1 to Induce Metastatic Dormancy PRINCIPAL...29 Sep 2017 4. TITLE AND SUBTITLE 5a. CONTRACT NUMBER Targeting Neutrophil Protease-Mediated Degradation of Tsp-1 to Induce Metastatic Dormancy...infection or cigarette smoke enhanced pulmonary metastasis from breast cancer in humans and mice. Similarly, autoimmune arthritis, characterized by

Principal Holistic Judgments and High-Stakes Evaluations of Teachers

Science.gov (United States)

Briggs, Derek C.; Dadey, Nathan

2017-01-01

Results from a sample of 1,013 Georgia principals who rated 12,617 teachers are used to compare holistic and analytic principal judgments with indicators of student growth central to the state's teacher evaluation system. Holistic principal judgments were compared to mean student growth percentiles (MGPs) and analytic judgments from a formal…

Job Satisfaction of Elementary Principals in Large Urban Communities

Science.gov (United States)

Mitchell, Cathryn M.

2010-01-01

The purpose of this study was to determine job satisfaction levels of elementary principals in "major urban" districts in Texas and to identify strategies these principals used to cope with the demands of the position. Additionally, the project sought to find structures and supports needed to attract and retain principals in the…

Empowering communication as an aspect of managerial communication in the training and development of principals

OpenAIRE

2012-01-01

D.Ed. On surveying education in South Africa, it becomes clear that there is a vast and pervasive effort to reform schools. Criticism from several quarters regarding the lack of effective managerial skills of principals including empowering communication indicates the importance of research into the communicative competencies of educational managers. The development of training programmes in effective communication skills for principals is thus imperative. A group of M.Ed. students from th...

Simultaneous Vascular Targeting and Tumor Targeting of Cerebral Breast Cancer Metastases Using a T-Cell Receptor Mimic Antibody

Science.gov (United States)

2014-05-01

in May 2013, the difference between nude mice (which lack T- cells , but still have a partially functional adaptive and innate immune system) and NSG...Mangada J, Greiner DL, Handgretinger R. Human lymphoid and myeloid cell development in NOD/LtSz-scid IL2R gamma null mice engrafted with mobilized human...Targeting of Cerebral Breast Cancer Metastases Using a T- Cell Receptor Mimic Antibody PRINCIPAL INVESTIGATOR: Ulrich Bickel

Record of principal work activities/deliverables

International Nuclear Information System (INIS)

1989-09-01

Over the five year period of performance, thirteen task assignments were issued by the DOE to ARINC Research. During the two year base period seven tasks were assigned. Two task assignments were issued for each of the three consecutive one year option periods. Associated with all task assignments were multiple subtasks, some of which required significant effort. These subtasks are appropriately cited in this report under their respective task assignments as principal work activities or deliverables. The technical and management support provided to the DOE under this contract focused on two general areas: (1) appraisal activities and (2) non-appraisal activities. Support to appraisals included planning, document review, developing lines-of-inquiry, interviewing, data collection, report writing, and follow-up. Such work was executed both on-site at the DOE facility under review and off-site. Non-appraisal support was varied and included such areas as document review, data base development, technical assessments. statistical analysis, policy analysis, reliability engineering, and workshop and conference planning and execution

Gene targeting using homologous recombination in embryonic stem cells: The future for behavior genetics?

Directory of Open Access Journals (Sweden)

Robert eGerlai

2016-04-01

Full Text Available Gene targeting with homologous recombination in embryonic stem cells created a revolution in the analysis of the function of genes in behavioral brain research. The technology allowed unprecedented precision with which one could manipulate genes and study the effect of this manipulation on the central nervous system. With gene targeting, the uncertainty inherent in psychopharmacology regarding whether a particular compound would act only through a specific target was removed. Thus, gene targeting became highly popular. However, with this popularity came the realization that like other methods, gene targeting also suffered from some technical and principal problems. For example, two decades ago, issues about compensatory changes and about genetic linkage were raised. Since then, the technology developed, and its utility has been better delineated. This review will discuss the pros and cons of the technique along with these advancements from the perspective of the neuroscientist user. It will also compare and contrast methods that may represent novel alternatives to the homologous recombination based gene targeting approach, including the TALEN and the CRISPR/Cas9 systems. The goal of the review is not to provide detailed recipes, but to attempt to present a short summary of these approaches a behavioral geneticist or neuroscientist may consider for the analysis of brain function and behavior.

Principal Component Analysis: Resources for an Essential Application of Linear Algebra

Science.gov (United States)

Pankavich, Stephen; Swanson, Rebecca

2015-01-01

Principal Component Analysis (PCA) is a highly useful topic within an introductory Linear Algebra course, especially since it can be used to incorporate a number of applied projects. This method represents an essential application and extension of the Spectral Theorem and is commonly used within a variety of fields, including statistics,…

Building Leadership Capacity to Support Principal Succession

Science.gov (United States)

Escalante, Karen Elizabeth

2016-01-01

This study applies transformational leadership theory practices, specifically inspiring a shared vision, modeling the way and enabling others to act to examine the purposeful ways in which principals work to build the next generation of teacher leaders in response to the dearth of K-12 principals. The purpose of this study was to discover how one…

How Do Principals Conceptualize Success: Are Their Actions Consistent with Their Definitions?

Science.gov (United States)

Patience, Brian J.

2012-01-01

My research study explored how principals allocated their time, their perceptions of success, and whether their actions were consistent with their definition of success. Findings revealed participants spent time performing three primary behaviors including communicating with school stakeholders, completing managerial practices, and serving as…

Study of Characters in Story of School Principal (Modir Madrese

Directory of Open Access Journals (Sweden)

Ghadamzli Sarrami

2013-05-01

Full Text Available Abstract It is concluded from the story that the reader to be briefed on the writer that he is fully aware of the education system process, furthermore it signifies that the inefficiency and distortion virtually experienced in the field of education affect the life cycle of the author as well.  Modir Madrese or School Principal is a fiction composed by Jalale Aleahmad a writer with genre of third person addressee, he narrates the biography of a teacher that he got tired of his job therefore he got his mind to assume the post of school principal, he reached to the favorite post by bribery as a result the previous teacher turned to school principal, the school situated at the slope of mountain.  The principal encountered with seven teachers, a janitor and 235 student who were mostly poor, geographical status, hygienic Services, yard, pond and school insufficient facilities which outlined as major shortcomings in the story.  Cognizance of students` parents, local council and establishment of school and home association, pornographies carried by a student, injury of 4th grade class teacher by car of an American citizen, jail of 3 grade class teacher due to sympathy toward socialists, appearing the accountant of education dept at the school asking for bribery and finally sexual scandal by 5th grade student counted as the major parts of the story , the whole incidences forced the principal to resign.  The current story represented in three perspectives like prose, simplicity and motive.  Motive signifies the text of story in social style it means realism fad while the prose depicts soft and colloquial by contribution of simile, explanations, proverbs and folkloric idioms, the stressed discourses, sarcasms and mockery including intensive and expressive prose manifested by representation of samples drawn out from the text.  The prominent part of the criticism revealed by analysis of story characters, as a result criticism of individual characters

Study of Characters in Story of School Principal (Modir Madrese

Directory of Open Access Journals (Sweden)

Dr Ghadamzli Sarrami , Mohammad Moghiseh

2013-01-01

Full Text Available It is concluded from the story that the reader to be briefed on the writer that he is fully aware of the education system process, furthermore it signifies that the inefficiency and distortion virtually experienced in the field of education affect the life cycle of the author as well. Modir Madrese or School Principal is a fiction composed by Jalale Aleahmad a writer with genre of third person addressee, he narrates the biography of a teacher that he got tired of his job therefore he got his mind to assume the post of school principal, he reached to the favorite post by bribery as a result the previous teacher turned to school principal, the school situated at the slope of mountain. The principal encountered with seven teachers, a janitor and 235 student who were mostly poor, geographical status, hygienic Services, yard, pond and school insufficient facilities which outlined as major shortcomings in the story. Cognizance of students` parents, local council and establishment of school and home association, pornographies carried by a student, injury of 4th grade class teacher by car of an American citizen, jail of 3 grade class teacher due to sympathy toward socialists, appearing the accountant of education dept at the school asking for bribery and finally sexual scandal by 5th grade student counted as the major parts of the story , the whole incidences forced the principal to resign. The current story represented in three perspectives like prose, simplicity and motive. Motive signifies the text of story in social style it means realism fad while the prose depicts soft and colloquial by contribution of simile, explanations, proverbs and folkloric idioms, the stressed discourses, sarcasms and mockery including intensive and expressive prose manifested by representation of samples drawn out from the text. The prominent part of the criticism revealed by analysis of story characters, as a result criticism of individual characters demonstrate symbol of

Multilevel sparse functional principal component analysis.

Science.gov (United States)

Di, Chongzhi; Crainiceanu, Ciprian M; Jank, Wolfgang S

2014-01-29

We consider analysis of sparsely sampled multilevel functional data, where the basic observational unit is a function and data have a natural hierarchy of basic units. An example is when functions are recorded at multiple visits for each subject. Multilevel functional principal component analysis (MFPCA; Di et al. 2009) was proposed for such data when functions are densely recorded. Here we consider the case when functions are sparsely sampled and may contain only a few observations per function. We exploit the multilevel structure of covariance operators and achieve data reduction by principal component decompositions at both between and within subject levels. We address inherent methodological differences in the sparse sampling context to: 1) estimate the covariance operators; 2) estimate the functional principal component scores; 3) predict the underlying curves. Through simulations the proposed method is able to discover dominating modes of variations and reconstruct underlying curves well even in sparse settings. Our approach is illustrated by two applications, the Sleep Heart Health Study and eBay auctions.

Threat Assessment and Targeted Violence at Institutions of Higher Education: Implications for Policy and Practice Including Unique Considerations for Community Colleges

Science.gov (United States)

Bennett, Laura; Bates, Michael

2015-01-01

This article provides an overview of the research on targeted violence, including campus violence, and the implications for policy and practice at institutions of higher education. Unique challenges of threat assessment in the community college setting are explored, and an overview of an effective threat assessment policy and team at William…

Principal noncommutative torus bundles

DEFF Research Database (Denmark)

Echterhoff, Siegfried; Nest, Ryszard; Oyono-Oyono, Herve

2008-01-01

of bivariant K-theory (denoted RKK-theory) due to Kasparov. Using earlier results of Echterhoff and Williams, we shall give a complete classification of principal non-commutative torus bundles up to equivariant Morita equivalence. We then study these bundles as topological fibrations (forgetting the group...

A Knock-in Reporter for a Novel AR-Targeted Therapy

Science.gov (United States)

2016-05-01

AWARD NUMBER: W81XWH-15-1-0049 TITLE: A Knock -in Reporter for a Novel AR-Targeted Therapy PRINCIPAL INVESTIGATOR: Chunhong Yan, Ph.D...5a. CONTRACT NUMBER A Knock -in Reporter for a Novel AR-Targeted Therapy 5b. GRANT NUMBER W81XWH-15-1-0049 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S...enhancer. While the knock -in reporter is expected to faithfully reproduce chemical responses of the endogenous AR gene, we carried out a pilot screen

African-American Female Students and STEM: Principals' Leadership Perspectives

Science.gov (United States)

Sampson, Kristin Morgan

As the U.S. becomes more diverse, school leaders, major corporations, and areas of national defense continue to investigate science, technology, engineering and math (STEM) education issues. African-American female students have historically been underrepresented in STEM fields, yet educational leadership research, examining this population is limited. The purpose of this qualitative study was to explore how principals support African-American female students in schools with a STEM program. The Critical Race Theory (CRT)was used as a theoretical framework to highlight the inadequacies to support educational inequalities. The application of the CRT in this study is due to the embedded inequality practices within the educational system, that have resulted in the underrepresentation of African-American female students in STEM. To complement CRT, the transformative leadership model was also utilized to examine the emancipatory leadership practices principals utilized. These theories framed the context of this study by recognizing the need to address how support is actualized to African-American female students in STEM by their principals. A case study approach was an appropriate method to answer the two research questions, 1) How do principals feel they support African-American female students in their STEM programs? and 2) What practices do principals engage in that support underrepresented students in STEM? This approach intended to uncover how a principal leads a multifaceted population of underrepresented students in STEM programs. Two principals of STEM schools, where more than 50% of the population were African-American, were interviewed and observed completing daily operations at community-wide events. The STEM Coordinators and a teacher were also interviewed, and test scores were examined to provide further information about the STEM program, and public records were obtained to analyze the principals' means of communication. I found that principals supported

EphB1 as a Novel Drug Target to Combat Pain and Addiction

Science.gov (United States)

2017-09-01

AWARD NUMBER: W81XWH-14-1-0220 TITLE: EphB1 as a Novel Drug Target to Combat Pain and Addiction PRINCIPAL INVESTIGATOR: Mark Henkemeyer...as a Novel Drug Target to Combat Pain and Ad 5a. CONTRACT NUMBER EphB1 as a Novel Drug Target to Combat Pain and Addiction 5b. GRANT NUMBER W81XWH...neuronal and has functions in vascular endothelial cells. 6. We have also carried out computational analysis of potantial docking/binding of chemical

Incremental Tensor Principal Component Analysis for Handwritten Digit Recognition

Directory of Open Access Journals (Sweden)

Chang Liu

2014-01-01

Full Text Available To overcome the shortcomings of traditional dimensionality reduction algorithms, incremental tensor principal component analysis (ITPCA based on updated-SVD technique algorithm is proposed in this paper. This paper proves the relationship between PCA, 2DPCA, MPCA, and the graph embedding framework theoretically and derives the incremental learning procedure to add single sample and multiple samples in detail. The experiments on handwritten digit recognition have demonstrated that ITPCA has achieved better recognition performance than that of vector-based principal component analysis (PCA, incremental principal component analysis (IPCA, and multilinear principal component analysis (MPCA algorithms. At the same time, ITPCA also has lower time and space complexity.

What Are the Targets of Inflammatory Bowel Disease Management.

Science.gov (United States)

Lega, Sara; Dubinsky, Marla C

2018-04-25

With recent evidence suggesting that keeping the inflammatory process under tight control prevents long-term disability, the aim of treatments in inflammatory bowel disease (IBD) has shifted from symptom control toward the resolution of bowel inflammation. Mucosal healing is currently recognized as the principal treatment target to be used in a "treat to target" paradigm, whereas histologic healing and normalization of biomarkers are being evaluated as potential future targets. Although symptom relief is no longer a sufficient target, patient experience with the disease is of unquestionable importance and should be assessed in the form of patient-reported outcomes, to be used as a co-primary target with an objective measure of disease activity. IBD in is a heterogeneous disease; thus besides defining common treatment targets, every effort should be made to deliver a personalized treatment plan based on the risk factors for disease progression and individual drug metabolism to improve treatment success.

APPRIS 2017: principal isoforms for multiple gene sets

Science.gov (United States)

Rodriguez-Rivas, Juan; Di Domenico, Tomás; Vázquez, Jesús; Valencia, Alfonso

2018-01-01

Abstract The APPRIS database (http://appris-tools.org) uses protein structural and functional features and information from cross-species conservation to annotate splice isoforms in protein-coding genes. APPRIS selects a single protein isoform, the ‘principal’ isoform, as the reference for each gene based on these annotations. A single main splice isoform reflects the biological reality for most protein coding genes and APPRIS principal isoforms are the best predictors of these main proteins isoforms. Here, we present the updates to the database, new developments that include the addition of three new species (chimpanzee, Drosophila melangaster and Caenorhabditis elegans), the expansion of APPRIS to cover the RefSeq gene set and the UniProtKB proteome for six species and refinements in the core methods that make up the annotation pipeline. In addition APPRIS now provides a measure of reliability for individual principal isoforms and updates with each release of the GENCODE/Ensembl and RefSeq reference sets. The individual GENCODE/Ensembl, RefSeq and UniProtKB reference gene sets for six organisms have been merged to produce common sets of splice variants. PMID:29069475

Large Covariance Estimation by Thresholding Principal Orthogonal Complements.

Science.gov (United States)

Fan, Jianqing; Liao, Yuan; Mincheva, Martina

2013-09-01

This paper deals with the estimation of a high-dimensional covariance with a conditional sparsity structure and fast-diverging eigenvalues. By assuming sparse error covariance matrix in an approximate factor model, we allow for the presence of some cross-sectional correlation even after taking out common but unobservable factors. We introduce the Principal Orthogonal complEment Thresholding (POET) method to explore such an approximate factor structure with sparsity. The POET estimator includes the sample covariance matrix, the factor-based covariance matrix (Fan, Fan, and Lv, 2008), the thresholding estimator (Bickel and Levina, 2008) and the adaptive thresholding estimator (Cai and Liu, 2011) as specific examples. We provide mathematical insights when the factor analysis is approximately the same as the principal component analysis for high-dimensional data. The rates of convergence of the sparse residual covariance matrix and the conditional sparse covariance matrix are studied under various norms. It is shown that the impact of estimating the unknown factors vanishes as the dimensionality increases. The uniform rates of convergence for the unobserved factors and their factor loadings are derived. The asymptotic results are also verified by extensive simulation studies. Finally, a real data application on portfolio allocation is presented.

Location and characterisation of pollution sites by principal ...

African Journals Online (AJOL)

Location and characterisation of pollution sites by principal component analysis of trace contaminants in a slightly polluted seasonal river: a case study of the Arenales River (Salta, Argentina) ... Keywords: trace element contamination, water quality, principal component analysis, Arenales River, Salta, Argentina ...

Two Charter School Principals' Engagement in Instructional Leadership

Science.gov (United States)

Bickmore, Dana L.; Sulentic Dowell, Margaret-Mary

2014-01-01

This comparative case (Merriam, 2009) study explored two charter school principals' engagement in instructional leadership. Analysis of three data sources--interviews, observations, and documents--revealed that principals were almost exclusively focused on state accountability and possessed limited knowledge of pedagogical practices. In…

Empowering principals to lead and manage public schools ...

African Journals Online (AJOL)

Globally, education systems have been affected by radical social, political and economic changes. Although school principals play a pivotal role in improving student learning and attaining educational outcomes, they work under strenuous conditions to deal with multifaceted transformational issues. Principals experience ...

Implementing a Principal Tutor to Increase Student Engagement and Retention within the First Year of a Professional Program

Directory of Open Access Journals (Sweden)

Jason Lodge

2012-03-01

Full Text Available With ongoing changes to the requirements for professional registration, greater demand for professional services, and targets for increasing participation, universities must adapt quickly to ensure that the quality of accredited professional programs is continually improving. The problem of retaining students is particularly relevant in accredited professional courses where students often have unrealistic expectations about course content and the profession. In order to address issues surrounding student engagement and retention in an accredited psychology course, a Principal Tutor was appointed to a first year cohort. By using a transition pedagogy framework to support student engagement through incorporating administrative and profession-specific advice within and outside the formal curriculum, the program appears to have been successful in increasing student engagement. Indicators of student engagement were higher than national averages and retention rates improved. Implications for possible application of the initiatives included in this program elsewhere are discussed. 

Blocking Breast Cancer Metastasis by Targeting RNA-Binding Protein HuR

Science.gov (United States)

2017-10-01

AWARD NUMBER: W81XWH-16-1-0730 TITLE: Blocking Breast Cancer Metastasis by Targeting RNA-Binding Protein HuR PRINCIPAL INVESTIGATOR: Danny Welch...NUMBER Blocking Breast Cancer Metastasis by Targeting RNA-Binding Protein HuR 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) 5d. PROJECT...increased aggressiveness in breast cancer , the primary objective of this proposal is to assess whether HuR (or analogs) prevent and/or treat metastasis and/or

Euler principal component analysis

NARCIS (Netherlands)

Liwicki, Stephan; Tzimiropoulos, Georgios; Zafeiriou, Stefanos; Pantic, Maja

Principal Component Analysis (PCA) is perhaps the most prominent learning tool for dimensionality reduction in pattern recognition and computer vision. However, the ℓ 2-norm employed by standard PCA is not robust to outliers. In this paper, we propose a kernel PCA method for fast and robust PCA,

School Principals' Perceptions of Ethically Just Responses to a Student Sexting Vignette: Severity of Administrator Response, Principal Personality, and Offender Gender and Race

Science.gov (United States)

Moriarty, Margaret E.

2012-01-01

This mixed-methods study was designed to determine how principals perceived the ethicality of sanctions for students engaged in sexting behavior relative to the race/ethnicity and gender of the student. Personality traits of the principals were surveyed to determine if Openness and/or Conscientiousness would predict principal response. Sexting is…

Use of Sparse Principal Component Analysis (SPCA) for Fault Detection

DEFF Research Database (Denmark)

Gajjar, Shriram; Kulahci, Murat; Palazoglu, Ahmet

2016-01-01

Principal component analysis (PCA) has been widely used for data dimension reduction and process fault detection. However, interpreting the principal components and the outcomes of PCA-based monitoring techniques is a challenging task since each principal component is a linear combination of the ...

Informing principal policy reforms in South Africa through data-based evidence

Directory of Open Access Journals (Sweden)

Gabrielle Wills

2015-12-01

Full Text Available In the past decade there has been a notable shift in South African education policy that raises the value of school leadership as a lever for learning improvements. Despite a growing discourse on school leadership, there has been a lack of empirical based evidence on principals to inform, validate or debate the efficacy of proposed policies in raising the calibre of school principals. Drawing on findings from a larger study to understand the labour market for school principals in South Africa, this paper highlights four overarching characteristics of this market with implications for informing principal policy reforms. The paper notes that improving the design and implementation of policies guiding the appointment process for principals is a matter of urgency. A substantial and increasing number of principal replacements are taking place across South African schools given a rising age profile of school principals. In a context of low levels of principal mobility and high tenure, the leadership trajectory of the average school is established for nearly a decade with each principal replacement. Evidence-based policy making has a strong role to play in getting this right.

Delegation of Monitoring in a Principal-Agent Relationship

NARCIS (Netherlands)

Strausz, R.G.

1995-01-01

This paper studies a principal-agent relationship with moral hazard in which the principal or the supervisor can monitor the agent's hidden action by using identical monitoring technologies. The paper shows that delegation of monitoring to the supervisor is profitable because of two effects. With

COMPETENCE OF SCHOOL PRINCIPALS REGARDING KNOWLEDGE MANAGEMENT IN ELEMENTARY SCHOOLS

Directory of Open Access Journals (Sweden)

Gökmen DAĞLI

2007-12-01

Full Text Available This research aims to determine the manner of school principals regarding knowledge managementin primary school education. The research is a subjective one conducted in general scanning method. Personal informationform and five-likert scale are the main means in which data was collected. During the data collection stage, school principalswere requested to provide information about the way in which they obtain, share, process, evaluate knowledge, take decisionand analyze problems within the scope of knowledge management. In the virtue of the data acquired, the research shows that;the school principals obtain knowledge by attending meetings with teachers, making personal observation, their personalexperience and online resources. Regarding the sharing of knowledge, the research shows the principals always shareknowledge with their assistant principals and teachers; in using of knowledge, decision making and analyzing problemsresearch also shows that principals take decisions in co-operation with assistant principals and teachers. Last but not least,research shows that in storing the knowledge principals mainly use computers and traditional filing techniques. Seminarsshould be organized periodically by specialists with respect to acquiring, sharing, using and also filling knowledge followingdecision-making in order for school administrators to keep abreast of the latest developments in knowledge management

How the Principalship Has Changed: Lessons from Principals' Life Stories.

Science.gov (United States)

Brubaker, Dale L.

1995-01-01

The life stories of (North Carolina) principals in a graduate education class reveal vast changes over the past 20 years. "Good ol' boy" superintendents and principals have been replaced by self-interested political "sharks" concerned more with image than substance. Fortunately, principals with resiliency, caring values, and…

The Principal-Agent model and the European Union

NARCIS (Netherlands)

Delreux, Tom; Adriaensen, J.

2017-01-01

This book assesses the use and limitations of the principal-agent model in a context of increasingly complex political systems such as the European Union. Whilst a number of conceptual, theoretical and methodological challenges need to be addressed, the authors show that the principal-agent model

Career Paths in Educational Leadership: Examining Principals' Narratives

Science.gov (United States)

Parylo, Oksana; Zepeda, Sally J.; Bengtson, Ed

2012-01-01

This qualitative study analyzes the career path narratives of active principals. Structural narrative analysis was supplemented with sociolinguistic theory and thematic narrative analysis to discern the similarities and differences, as well as the patterns in the language used by participating principals. Thematic analysis found four major themes…

Principals' Perceptions of Their Knowledge in Special Education

Science.gov (United States)

Roberts, Maria Banda; Guerra, Federico R., Jr.

2017-01-01

With the "Every Student Succeeds Act" continuing to legislate accountability for special education and Hispanic students, the appropriate content in principal preparation programs relevant to successful leadership of special education programs is vital. This mixed methods study analyzed the survey responses of 84 principals in South…

Learning Leaders: How Do Award-Winning Principals Learn and Grow? Are There Commonalities in the Professional Development Practices of NAESP/NASSP Award-Winning Principals?

Science.gov (United States)

Hansen, Mark

2013-01-01

The role a principal plays in school improvement has evolved over time. The transition from principal as manager to principal as instructional leader began with and was driven in large part by the effective schools movement of the 1970's and 1980's (Hallinger, 2003; Zigarelli, 1996). Since the inception of NCLB in 2001, the leader's role in…

Study of Characters in Story of School Principal (Modir Madrese

Directory of Open Access Journals (Sweden)

Ghadamzli Sarrami

2013-04-01

Full Text Available  Abstract It is concluded from the story that the reader to be briefed on the writer that he is fully aware of the education system process, furthermore it signifies that the inefficiency and distortion virtually experienced in the field of education affect the life cycle of the author as well.  Modir Madrese or School Principal is a fiction composed by Jalale Aleahmad a writer with genre of third person addressee, he narrates the biography of a teacher that he got tired of his job therefore he got his mind to assume the post of school principal, he reached to the favorite post by bribery as a result the previous teacher turned to school principal, the school situated at the slope of mountain.  The principal encountered with seven teachers, a janitor and 235 student who were mostly poor, geographical status, hygienic Services, yard, pond and school insufficient facilities which outlined as major shortcomings in the story.  Cognizance of students` parents, local council and establishment of school and home association, pornographies carried by a student, injury of 4th grade class teacher by car of an American citizen, jail of 3 grade class teacher due to sympathy toward socialists, appearing the accountant of education dept at the school asking for bribery and finally sexual scandal by 5th grade student counted as the major parts of the story , the whole incidences forced the principal to resign.  The current story represented in three perspectives like prose, simplicity and motive.  Motive signifies the text of story in social style it means realism fad while the prose depicts soft and colloquial by contribution of simile, explanations, proverbs and folkloric idioms, the stressed discourses, sarcasms and mockery including intensive and expressive prose manifested by representation of samples drawn out from the text.  The prominent part of the criticism revealed by analysis of story characters, as a result criticism of

Common Core Implementation Decisions Made by Principals in Elementary Schools

Science.gov (United States)

Norman, Alexis Cienfuegos

2016-01-01

The purpose of this study was to understand the decisions elementary principals have made during the Common Core State Standards reform. Specifically, (a) what decisions principals have made to support Common Core implementation, (b) what strategies elementary principals have employed to communicate with stakeholders about Common Core State…

Principals' Perception of Educational Inputs and Students' Academic ...

African Journals Online (AJOL)

This study investigated principals' perception of the relationship between educational inputs and academic performance of students in public junior secondary schools (JSS) in the Central Senatorial District of Delta State, Nigeria. The population was all the 173 public JSS and their principals from which a sample of twenty ...

Principal Preservice Education for Leadership in Inclusive Schools

Science.gov (United States)

Lyons, Wanda

2016-01-01

Principal leadership has been identified as the key to successful implementation of inclusive education for students with disabilities. Prospective principals require knowledge, skills, and dispositions to equip them to work with key stakeholders to initiate and sustain inclusive practices within their schools. The purpose of this action research…

Teacher Contract Non-Renewal: What Matters to Principals?

Science.gov (United States)

Nixon, Andy; Packard, Abbot; Dam, Margaret

2016-01-01

This quantitative study investigated the relationship between teacher dispositions, subject content knowledge, pedagogical content knowledge, and reasons that school principals recommend non-renewal of teachers' contracts. Nearly 2,000 school principals in 13 states completed an emailed survey. In deciding whether to non-renew a teacher contract,…

A free-jet Hg target operating in a high magnetic field intersecting a high-power proton beam

Science.gov (United States)

Van Graves; Spampinato, Philip; Gabriel, Tony; Kirk, Harold; Simos, Nicholas; Tsang, Thomas; McDonald, Kirk; Peter Titus; Fabich, Adrian; Haseroth, Helmut; Lettry, Jacques

2006-06-01

A proof-of-principal experiment to investigate the interaction of a proton beam, high magnetic field, and high- Z target is planned to take place at CERN in early 2007. This experiment is part of the Muon Collider Collaboration, with participants from Brookhaven National Laboratory, Princeton University, Massachusetts Institute Of Technology, European Organization for Nuclear Research-CERN, Rutherford Appleton Laboratory, and Oak Ridge National Laboratory. An unconstrained mercury jet target system that interacts with a high power (1 MW) proton beam in a high magnetic field (15 T) is being designed. The Hg jet diameter is 1-cm with a velocity up to 20 m/s. A laser optical diagnostic system will be incorporated into the target design to permit observation of the dispersal of the jet resulting from interaction with a 24 GeV proton beam with up to 20×10 12 ppp. The target system includes instruments for sensing mercury vapor, temperature, flow rate, and sump tank level, and the means to position the jet relative to the magnetic axis of a solenoid and the proton beam. The design considerations for the system include all issues dealing with safely handling approximately 23 l of Hg, transporting the target system and the mercury to CERN, decommissioning the experiment, and returning the mildly activated equipment and Hg to the US.

Principal component analysis of FDG PET in amnestic MCI

International Nuclear Information System (INIS)

Nobili, Flavio; Girtler, Nicola; Brugnolo, Andrea; Dessi, Barbara; Rodriguez, Guido; Salmaso, Dario; Morbelli, Silvia; Piccardo, Arnoldo; Larsson, Stig A.; Pagani, Marco

2008-01-01

The purpose of the study is to evaluate the combined accuracy of episodic memory performance and 18 F-FDG PET in identifying patients with amnestic mild cognitive impairment (aMCI) converting to Alzheimer's disease (AD), aMCI non-converters, and controls. Thirty-three patients with aMCI and 15 controls (CTR) were followed up for a mean of 21 months. Eleven patients developed AD (MCI/AD) and 22 remained with aMCI (MCI/MCI). 18 F-FDG PET volumetric regions of interest underwent principal component analysis (PCA) that identified 12 principal components (PC), expressed by coarse component scores (CCS). Discriminant analysis was performed using the significant PCs and episodic memory scores. PCA highlighted relative hypometabolism in PC5, including bilateral posterior cingulate and left temporal pole, and in PC7, including the bilateral orbitofrontal cortex, both in MCI/MCI and MCI/AD vs CTR. PC5 itself plus PC12, including the left lateral frontal cortex (LFC: BAs 44, 45, 46, 47), were significantly different between MCI/AD and MCI/MCI. By a three-group discriminant analysis, CTR were more accurately identified by PET-CCS + delayed recall score (100%), MCI/MCI by PET-CCS + either immediate or delayed recall scores (91%), while MCI/AD was identified by PET-CCS alone (82%). PET increased by 25% the correct allocations achieved by memory scores, while memory scores increased by 15% the correct allocations achieved by PET. Combining memory performance and 18 F-FDG PET yielded a higher accuracy than each single tool in identifying CTR and MCI/MCI. The PC containing bilateral posterior cingulate and left temporal pole was the hallmark of MCI/MCI patients, while the PC including the left LFC was the hallmark of conversion to AD. (orig.)

Principal component analysis of FDG PET in amnestic MCI

Energy Technology Data Exchange (ETDEWEB)

Nobili, Flavio; Girtler, Nicola; Brugnolo, Andrea; Dessi, Barbara; Rodriguez, Guido [University of Genoa, Clinical Neurophysiology, Department of Endocrinological and Medical Sciences, Genoa (Italy); S. Martino Hospital, Alzheimer Evaluation Unit, Genoa (Italy); S. Martino Hospital, Head-Neck Department, Genoa (Italy); Salmaso, Dario [CNR, Institute of Cognitive Sciences and Technologies, Rome (Italy); CNR, Institute of Cognitive Sciences and Technologies, Padua (Italy); Morbelli, Silvia [University of Genoa, Nuclear Medicine Unit, Department of Internal Medicine, Genoa (Italy); Piccardo, Arnoldo [Galliera Hospital, Nuclear Medicine Unit, Department of Imaging Diagnostics, Genoa (Italy); Larsson, Stig A. [Karolinska Hospital, Department of Nuclear Medicine, Stockholm (Sweden); Pagani, Marco [CNR, Institute of Cognitive Sciences and Technologies, Rome (Italy); CNR, Institute of Cognitive Sciences and Technologies, Padua (Italy); Karolinska Hospital, Department of Nuclear Medicine, Stockholm (Sweden)

2008-12-15

The purpose of the study is to evaluate the combined accuracy of episodic memory performance and {sup 18}F-FDG PET in identifying patients with amnestic mild cognitive impairment (aMCI) converting to Alzheimer's disease (AD), aMCI non-converters, and controls. Thirty-three patients with aMCI and 15 controls (CTR) were followed up for a mean of 21 months. Eleven patients developed AD (MCI/AD) and 22 remained with aMCI (MCI/MCI). {sup 18}F-FDG PET volumetric regions of interest underwent principal component analysis (PCA) that identified 12 principal components (PC), expressed by coarse component scores (CCS). Discriminant analysis was performed using the significant PCs and episodic memory scores. PCA highlighted relative hypometabolism in PC5, including bilateral posterior cingulate and left temporal pole, and in PC7, including the bilateral orbitofrontal cortex, both in MCI/MCI and MCI/AD vs CTR. PC5 itself plus PC12, including the left lateral frontal cortex (LFC: BAs 44, 45, 46, 47), were significantly different between MCI/AD and MCI/MCI. By a three-group discriminant analysis, CTR were more accurately identified by PET-CCS + delayed recall score (100%), MCI/MCI by PET-CCS + either immediate or delayed recall scores (91%), while MCI/AD was identified by PET-CCS alone (82%). PET increased by 25% the correct allocations achieved by memory scores, while memory scores increased by 15% the correct allocations achieved by PET. Combining memory performance and {sup 18}F-FDG PET yielded a higher accuracy than each single tool in identifying CTR and MCI/MCI. The PC containing bilateral posterior cingulate and left temporal pole was the hallmark of MCI/MCI patients, while the PC including the left LFC was the hallmark of conversion to AD. (orig.)

Defamation of and by Principals. A Legal Memorandum.

Science.gov (United States)

Zirkel, Perry A.

Defamation is a common-law claim for liability that encompasses "libel," which is the written form, and "slander," which is the oral form. School principals can be plaintiffs or defendants in defamation suits. Relevant case law provides illustrations of the various elements of defamation for both roles of the principal. Court…

Principals' Perceptions of Needs in Hispanic Special Education

Science.gov (United States)

Roberts, Maria B.; Guerra, Federico, Jr.

2017-01-01

This mixed methods study used a survey by Frost and Kersten to answer the following questions: (a) Do principals of predominantly Hispanic schools perceive themselves as having adequate knowledge in special education? (b) Which areas are these principals most involved in with special education teachers? (c) What suggestions do these principals…

Primary School Principals' Job Satisfaction and Occupational Stress

Science.gov (United States)

Darmody, Merike; Smyth, Emer

2016-01-01

Purpose: The purpose of this paper is to explore the factors associated with occupational stress and job satisfaction among Irish primary school principals. A principal's job has become increasingly demanding and complex in recent decades. However, there is little current research into their levels of stress and job satisfaction, particularly…

Principals' Perceived Supervisory Behaviors Regarding Marginal Teachers in Two States

Science.gov (United States)

Range, Bret; Hewitt, Paul; Young, Suzie

2014-01-01

This descriptive study used an online survey to determine how principals in two states viewed the supervision of marginal teachers. Principals ranked their own evaluation of the teacher as the most important factor when identifying marginal teachers and relied on informal methods to diagnose marginal teaching. Female principals rated a majority of…

Analytic model of heat deposition in spallation neutron target

International Nuclear Information System (INIS)

Findlay, D.J.S.

2015-01-01

A simple analytic model for estimating deposition of heat in a spallation neutron target is presented—a model that can readily be realised in an unambitious spreadsheet. The model is based on simple representations of the principal underlying physical processes, and is intended largely as a ‘sanity check’ on results from Monte Carlo codes such as FLUKA or MCNPX.

Analytic model of heat deposition in spallation neutron target

Energy Technology Data Exchange (ETDEWEB)

Findlay, D.J.S.

2015-12-11

A simple analytic model for estimating deposition of heat in a spallation neutron target is presented—a model that can readily be realised in an unambitious spreadsheet. The model is based on simple representations of the principal underlying physical processes, and is intended largely as a ‘sanity check’ on results from Monte Carlo codes such as FLUKA or MCNPX.

relationship between principals' management approaches

African Journals Online (AJOL)

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Data were collected using a self-administered questionnaire from a sample of. 211 teachers, 28 principals and 22 chairpersons of parent- teachers association. Data were ..... their role expectation in discipline management. Data from the 20 ...

Honouring Roles: The Story of a Principal and a Student

Science.gov (United States)

Cranston, Jerome

2012-01-01

The importance of the teacher-student relationship in educational practice is well established, as is the idea of principal leadership in relationship to staff. Even though principal leadership is regarded as a factor in student success, the principal's effect is usually assumed to take place via the teaching staff. There is an absence of research…

Principals' Leadership Styles and ESL Teachers' Job Satisfaction

Science.gov (United States)

Jackson, K. A'jaydin

2013-01-01

The purpose of this research study was to examine principals' leadership styles and how and what extent it impacted teachers' job satisfaction. Principals' leadership styles were examined by middle and high school teachers' perceptions. This study drew from 10 middle and 10 high schools in a large school district located in Texas. Participants…

Latina/o School Principals: Identity, Leadership and Advocacy

Science.gov (United States)

Murakami, Elizabeth T.; Hernandez, Frank; Mendez-Morse, Sylvia; Byrne-Jimenez, Monica

2016-01-01

This study sought to further define and inform about the influence of Latina/o principals in schools as an alternative to traditional forms of leadership. The principals' Latina/o identity, their leadership styles and advocacy towards the improvement of student achievement were examined. This research focused on three questions: (a) How did…

Maintenance service contract model for heavy equipment in mining industry using principal agent theory

Science.gov (United States)

Pakpahan, Eka K. A.; Iskandar, Bermawi P.

2015-12-01

Mining industry is characterized by a high operational revenue, and hence high availability of heavy equipment used in mining industry is a critical factor to ensure the revenue target. To maintain high avaliability of the heavy equipment, the equipment's owner hires an agent to perform maintenance action. Contract is then used to control the relationship between the two parties involved. The traditional contracts such as fixed price, cost plus or penalty based contract studied is unable to push agent's performance to exceed target, and this in turn would lead to a sub-optimal result (revenue). This research deals with designing maintenance contract compensation schemes. The scheme should induce agent to select the highest possible maintenance effort level, thereby pushing agent's performance and achieve maximum utility for both parties involved. Principal agent theory is used as a modeling approach due to its ability to simultaneously modeled owner and agent decision making process. Compensation schemes considered in this research includes fixed price, cost sharing and revenue sharing. The optimal decision is obtained using a numerical method. The results show that if both parties are risk neutral, then there are infinite combination of fixed price, cost sharing and revenue sharing produced the same optimal solution. The combination of fixed price and cost sharing contract results in the optimal solution when the agent is risk averse, while the optimal combination of fixed price and revenue sharing contract is obtained when agent is risk averse. When both parties are risk averse, the optimal compensation scheme is a combination of fixed price, cost sharing and revenue sharing.

The Principal as CEO

Science.gov (United States)

Hollar, Charlie

2004-01-01

They may never grace the pages of The Wall Street Journal or Fortune magazine, but they might possibly be the most important CEOs in our country. They are elementary school principals. Each of them typically serves the learning needs of 350-400 clients (students) while overseeing a multimillion-dollar facility staffed by 20-25 teachers and 10-15…

Missing the target: including perspectives of women with overweight and obesity to inform stigma-reduction strategies.

Science.gov (United States)

Puhl, R M; Himmelstein, M S; Gorin, A A; Suh, Y J

2017-03-01

Pervasive weight stigma and discrimination have led to ongoing calls for efforts to reduce this bias. Despite increasing research on stigma-reduction strategies, perspectives of individuals who have experienced weight stigma have rarely been included to inform this research. The present study conducted a systematic examination of women with high body weight to assess their perspectives about a broad range of strategies to reduce weight-based stigma. Women with overweight or obesity ( N  = 461) completed an online survey in which they evaluated the importance, feasibility and potential impact of 35 stigma-reduction strategies in diverse settings. Participants (91.5% who reported experiencing weight stigma) also completed self-report measures assessing experienced and internalized weight stigma. Most participants assigned high importance to all stigma-reduction strategies, with school-based and healthcare approaches accruing the highest ratings. Adding weight stigma to existing anti-harassment workplace training was rated as the most impactful and feasible strategy. The family environment was viewed as an important intervention target, regardless of participants' experienced or internalized stigma. These findings underscore the importance of including people with stigmatized identities in stigma-reduction research; their insights provide a necessary and valuable contribution that can inform ways to reduce weight-based inequities and prioritize such efforts.

Principal component regression for crop yield estimation

CERN Document Server

Suryanarayana, T M V

2016-01-01

This book highlights the estimation of crop yield in Central Gujarat, especially with regard to the development of Multiple Regression Models and Principal Component Regression (PCR) models using climatological parameters as independent variables and crop yield as a dependent variable. It subsequently compares the multiple linear regression (MLR) and PCR results, and discusses the significance of PCR for crop yield estimation. In this context, the book also covers Principal Component Analysis (PCA), a statistical procedure used to reduce a number of correlated variables into a smaller number of uncorrelated variables called principal components (PC). This book will be helpful to the students and researchers, starting their works on climate and agriculture, mainly focussing on estimation models. The flow of chapters takes the readers in a smooth path, in understanding climate and weather and impact of climate change, and gradually proceeds towards downscaling techniques and then finally towards development of ...

School Principals' Technology Leadership Competency and Technology Coordinatorship

Science.gov (United States)

Banoglu, Koksal

2011-01-01

The aim of this study is to determine the primary and high school principals' competency in technology leadership and so to define implications for advanced competency. The population of the study was formed by 134 school principals in Maltepe and Kadikoy districts in Istanbul. On account of the fact that population was reachable, no specific…

Implications for Research: Preparing Principals for Leadership Roles.

Science.gov (United States)

Hord, Shirley M.; Thurber, John C.

Recent research has shown that, to exercise more effective leadership, principals need to match their behaviors with the appropriate needs and concerns of teachers. Concepts and tools from work done by the Research on Concerns-Based Adoption Project at the Austin campus of the University of Texas were employed to provide principals in the Palm…

The Development of Faith Leadership in Novice Principals

Science.gov (United States)

Rieckhoff, Barbara Stacy

2014-01-01

This article describes the Catholic School Principal Support Program (CSPSP), a mentoring program for first and second-year Catholic school principals in a large urban diocese, and identifies key challenges, impacts and influences on decision-making. Ten school leaders describe their work and provide the lens by which they reflect on their role as…

Design and Characterization of High Power Targets for RIB Generation

International Nuclear Information System (INIS)

Zhang, Y.

2001-01-01

In this article, thermal modeling techniques are used to simulate ISOL targets irradiated with high power proton beams. Beam scattering effects, nuclear reactions and beam power deposition distributions in the target were computed with the Monte Carlo simulation code, GEANT4. The power density information was subsequently used as input to the finite element thermal analysis code, ANSYS, for extracting temperature distribution information for a variety of target materials. The principal objective of the studies was to evaluate techniques for more uniformly distributing beam deposited heat over the volumes of targets to levels compatible with their irradiation with the highest practical primary-beam power, and to use the preferred technique to design high power ISOL targets. The results suggest that radiation cooling, in combination, with primary beam manipulation, can be used to control temperatures in practically sized targets, to levels commensurate with irradiation with 1 GeV, 100 kW proton beams

First-Year Principal Encounters Homophobia

Science.gov (United States)

Retelle, Ellen

2011-01-01

A 1st-year principal encounters homonegativity and an ethical dilemma when she attempts to terminate a teacher because of the teacher's inadequate and ineffective teaching. The teacher responds by threatening to "out" Ms. L. to the parents.

Targeting TMPRSS2-ERG in Prostate Cancer

Science.gov (United States)

2017-11-01

AWARD NUMBER: W81XWH-13-1-0212 TITLE: Targeting TMPRSS2-ERG in Prostate Cancer PRINCIPAL INVESTIGATOR: David Takeda CONTRACTING...ORGANIZATION: Dana-Farber Cancer Institute Boston, MA 02215 REPORT DATE: November 2017 TYPE OF REPORT: Final PREPARED FOR: U.S. Army Medical Research...Prostate Cancer 5a. CONTRACT NUMBER 5b. GRANT NUMBER W81XWH-13-1-0212 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) David Takeda 5d. PROJECT NUMBER 5e

The Leadership Roles of a Principal in Improving School Effectiveness

Directory of Open Access Journals (Sweden)

Burhanuddin Burhanuddin

2016-02-01

Full Text Available The purpose of this study was to investigate the leadership roles and practices of the principal in improving school effectiveness. This descriptive study involved the principal , counselor, and 11 teachers from the Tonsley Park Primary School in South Australia. The findings showed that all respondents generally regarded team leader as the most important role, while supervisor was rated as the least important. Of the 20 tasks observed, generally revealed that a principal should work cooperatively with staff to ensure more effective use of their skills. While, the task of a principal in making decisions on staff development programs was not necessarily expected by the practicing teachers. All respondents considered organization coordination as the most important area within which a principal should provide more leadership, while curriculum or instructional improvement and innovation was regarded as the least important

Target recognition of ladar range images using even-order Zernike moments.

Science.gov (United States)

Liu, Zheng-Jun; Li, Qi; Xia, Zhi-Wei; Wang, Qi

2012-11-01

Ladar range images have attracted considerable attention in automatic target recognition fields. In this paper, Zernike moments (ZMs) are applied to classify the target of the range image from an arbitrary azimuth angle. However, ZMs suffer from high computational costs. To improve the performance of target recognition based on small samples, even-order ZMs with serial-parallel backpropagation neural networks (BPNNs) are applied to recognize the target of the range image. It is found that the rotation invariance and classified performance of the even-order ZMs are both better than for odd-order moments and for moments compressed by principal component analysis. The experimental results demonstrate that combining the even-order ZMs with serial-parallel BPNNs can significantly improve the recognition rate for small samples.

Large Covariance Estimation by Thresholding Principal Orthogonal Complements

Science.gov (United States)

Fan, Jianqing; Liao, Yuan; Mincheva, Martina

2012-01-01

This paper deals with the estimation of a high-dimensional covariance with a conditional sparsity structure and fast-diverging eigenvalues. By assuming sparse error covariance matrix in an approximate factor model, we allow for the presence of some cross-sectional correlation even after taking out common but unobservable factors. We introduce the Principal Orthogonal complEment Thresholding (POET) method to explore such an approximate factor structure with sparsity. The POET estimator includes the sample covariance matrix, the factor-based covariance matrix (Fan, Fan, and Lv, 2008), the thresholding estimator (Bickel and Levina, 2008) and the adaptive thresholding estimator (Cai and Liu, 2011) as specific examples. We provide mathematical insights when the factor analysis is approximately the same as the principal component analysis for high-dimensional data. The rates of convergence of the sparse residual covariance matrix and the conditional sparse covariance matrix are studied under various norms. It is shown that the impact of estimating the unknown factors vanishes as the dimensionality increases. The uniform rates of convergence for the unobserved factors and their factor loadings are derived. The asymptotic results are also verified by extensive simulation studies. Finally, a real data application on portfolio allocation is presented. PMID:24348088

Principals' and Teachers' Attitudes towards Inclusion in Israel

Science.gov (United States)

Hess, Itay; Zamir, Sara

2016-01-01

The main goal of this study was to determine whether, in schools that practice inclusion, there is a correlation between the attitudes of school principals and teachers in their schools, towards inclusion of student with special needs. For this purpose, 38 schools were sampled in each of which the school principal and five teachers who work with…

Shared sanitation: to include or to exclude?

Science.gov (United States)

Mara, Duncan

2016-05-01

Just over 600 million people used shared sanitation in 2015, but this form of sanitation is not considered 'improved sanitation' or, in the current terminology, 'basic sanitation' by WHO/UNICEF, principally because they are typically unhygienic. Recent research has shown that neighbour-shared toilets perform much better than large communal toilets. The successful development of community-designed, built and managed sanitation-and-water blocks in very poor urban areas in India should be adapted and adopted throughout urban slums in developing countries, with a caretaker employed to keep the facilities clean. Such shared sanitation should be classified as 'basic', sometimes as 'safely-managed', sanitation, so contributing to the achievement of the sanitation target of the Sustainable Development Goals. © The Author 2016. Published by Oxford University Press on behalf of Royal Society of Tropical Medicine and Hygiene. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

Development of a Novel Targeted RNAi Delivery Technology inTherapies for Metabolic Diseases

Science.gov (United States)

2017-10-01

report Impact on other disciplines: Nothing to report Impact on technology transfer: Nothing to report Impact on society : Nothing to report 5. CHANGES...AWARD NUMBER: W81XWH-15-1-0569 TITLE: Development of a Novel Targeted RNAi Delivery Technology in Therapies for Metabolic Diseases PRINCIPAL...COVERED 30Sep2016 - 29Sep2017 4. TITLE AND SUBTITLE Development of a Novel Targeted RNAi Delivery Technology in Therapies for Metabolic Diseases 5a

The drug target genes show higher evolutionary conservation than non-target genes.

Science.gov (United States)

Lv, Wenhua; Xu, Yongdeng; Guo, Yiying; Yu, Ziqi; Feng, Guanglong; Liu, Panpan; Luan, Meiwei; Zhu, Hongjie; Liu, Guiyou; Zhang, Mingming; Lv, Hongchao; Duan, Lian; Shang, Zhenwei; Li, Jin; Jiang, Yongshuai; Zhang, Ruijie

2016-01-26

Although evidence indicates that drug target genes share some common evolutionary features, there have been few studies analyzing evolutionary features of drug targets from an overall level. Therefore, we conducted an analysis which aimed to investigate the evolutionary characteristics of drug target genes. We compared the evolutionary conservation between human drug target genes and non-target genes by combining both the evolutionary features and network topological properties in human protein-protein interaction network. The evolution rate, conservation score and the percentage of orthologous genes of 21 species were included in our study. Meanwhile, four topological features including the average shortest path length, betweenness centrality, clustering coefficient and degree were considered for comparison analysis. Then we got four results as following: compared with non-drug target genes, 1) drug target genes had lower evolutionary rates; 2) drug target genes had higher conservation scores; 3) drug target genes had higher percentages of orthologous genes and 4) drug target genes had a tighter network structure including higher degrees, betweenness centrality, clustering coefficients and lower average shortest path lengths. These results demonstrate that drug target genes are more evolutionarily conserved than non-drug target genes. We hope that our study will provide valuable information for other researchers who are interested in evolutionary conservation of drug targets.

Effect of Principal and Student Gender on New York City High School Performance Outcomes

Directory of Open Access Journals (Sweden)

Rupert Green

2015-07-01

Full Text Available A mixed-methods study enabled the exploration of New York City high school data, analyzing performance/demographic scores based on principal and/or student gender, boroughs, and other factors found the following: Significant differences in boroughs’ college and career readiness scores, χ2(4, N = 369 = 26.830, p = .00, with (a the highest mean rank of 251 for Staten Island, and the lowest mean rank of 156 for Brooklyn; (b larger socioeconomically integrated schools more successful; (c failure in small Manhattan and Bronx segregated/poverty female-majority schools; and (d male students, F(4, 359 = 2.49, p = .043, partial η2 = .027, attained significantly lower scores. Enrollment was significant, F(1, 457 = 7.215, p < .05 partial η2 = .940, with male principals (M = 746.40, SD = 903.58 leading larger schools. Recommendations include the following: gifted vocational education school, gauging for feminization, more Black/Hispanic principals; and assurance of licensed vocational educators.

Radar target classification method with high accuracy and decision speed performance using MUSIC spectrum vectors and PCA projection

Science.gov (United States)

Secmen, Mustafa

2011-10-01

This paper introduces the performance of an electromagnetic target recognition method in resonance scattering region, which includes pseudo spectrum Multiple Signal Classification (MUSIC) algorithm and principal component analysis (PCA) technique. The aim of this method is to classify an "unknown" target as one of the "known" targets in an aspect-independent manner. The suggested method initially collects the late-time portion of noise-free time-scattered signals obtained from different reference aspect angles of known targets. Afterward, these signals are used to obtain MUSIC spectrums in real frequency domain having super-resolution ability and noise resistant feature. In the final step, PCA technique is applied to these spectrums in order to reduce dimensionality and obtain only one feature vector per known target. In the decision stage, noise-free or noisy scattered signal of an unknown (test) target from an unknown aspect angle is initially obtained. Subsequently, MUSIC algorithm is processed for this test signal and resulting test vector is compared with feature vectors of known targets one by one. Finally, the highest correlation gives the type of test target. The method is applied to wire models of airplane targets, and it is shown that it can tolerate considerable noise levels although it has a few different reference aspect angles. Besides, the runtime of the method for a test target is sufficiently low, which makes the method suitable for real-time applications.

Principals' Instructional Leadership within a Teacher Performance Appraisal System: Enhancing Students' Academic Success

Science.gov (United States)

Ovando, Martha N.; Ramirez, Alfredo, Jr.

2007-01-01

The purpose of this study was to identify principals' instructional leadership actions within a comprehensive teacher evaluation system in successful schools rated as recognized or exemplary by the accountability measures in place. The study followed a multiple case study approach. Participants included six school administrators within the same…

Female Principals in Education: Breaking the Glass Ceiling in Spain

Directory of Open Access Journals (Sweden)

Enrique Javier Diez Gutierrez

Full Text Available Abstract Spanish schools are characterised by having a high proportion of female staff. However, statistics show that a proportionately higher number of men hold leadership positions. The aim of this study was to analyse the reasons why this is so, and to determine the motivations and barriers that women encounter in attaining and exercising these positions of greater responsibility and power. Questionnaires were administered to 2,022 female teachers, 430 female principals and 322 male principals. In addition, semi-structured interviews were held with 60 female principals, 14 focus group discussions were held with female principals and 16 autobiographical narratives were compiled with female principals and school inspectors. The reasons identified were related to structural aspects linked to the patriarchal worldview that is still dominant in our society and culture. Nevertheless, we also found motivations among women for attaining and exercising leadership roles.

Twins and Kindergarten Separation: Divergent Beliefs of Principals, Teachers, Parents, and Twins

Science.gov (United States)

Gordon, Lynn Melby

2015-01-01

Should principals enforce mandatory separation of twins in kindergarten? Do school separation beliefs of principals differ from those of teachers, parents of twins, and twins themselves? This survey questioned 131 elementary principals, 54 kindergarten teachers, 201 parents of twins, and 112 twins. A majority of principals (71%) believed that…

78 FR 59383 - Principal Management Corporation, et al.; Notice of Application

Science.gov (United States)

2013-09-26

... sections 12(d)(1)(A) and (B) of the Act. Applicants: Principal Management Corporation (``PMC''), Principal... SECURITIES AND EXCHANGE COMMISSION [Investment Company Act Release No. 30692; 812-14136] Principal Management Corporation, et al.; Notice of Application September 20, 2013. AGENCY: Securities and Exchange...

Sparse logistic principal components analysis for binary data

KAUST Repository

Lee, Seokho

2010-09-01

We develop a new principal components analysis (PCA) type dimension reduction method for binary data. Different from the standard PCA which is defined on the observed data, the proposed PCA is defined on the logit transform of the success probabilities of the binary observations. Sparsity is introduced to the principal component (PC) loading vectors for enhanced interpretability and more stable extraction of the principal components. Our sparse PCA is formulated as solving an optimization problem with a criterion function motivated from a penalized Bernoulli likelihood. A Majorization-Minimization algorithm is developed to efficiently solve the optimization problem. The effectiveness of the proposed sparse logistic PCA method is illustrated by application to a single nucleotide polymorphism data set and a simulation study. © Institute ol Mathematical Statistics, 2010.

Heavy-ion targets

International Nuclear Information System (INIS)

Adair, H.L.; Kobisk, E.H.

1985-01-01

This chapter examines the characteristics of targets required in heavy-ion accelerator physics experiments. The effects of target parameters on heavy-ion experimental results are reviewed. The target fabrication and characterization techniques used to minimize experimental problems during heavy-ion bombardment are described. Topics considered include target thickness and uniformity, target lifetime, target purity, substrate materials, Doppler shift effects, metal preparations, and target preparation methods

TNK2 Tyrosine Kinase as a Novel Therapeutic Target in Triple-Negative Breast Cancer

Science.gov (United States)

2017-10-01

Award Number: W81XWH-15-1-0311 TITLE: TNK2 Tyrosine Kinase as a Novel Therapeutic Target in Triple- Negative Breast Cancer PRINCIPAL...Distribution Unlimited 13. SUPPLEMENTARY NOTES 14. ABSTRACT Triple-negative breast cancers (TNBCs) represent only 10%-15% of all breast cancers ; however... cancers (TNBC) represent 10-15% of all breast cancers . While significant advances have been made for targeted therapy of ER and HER2-positive breast

Development of Procedures for the Analysis of Components of Dumped Chemical Weapons and Their Principal Transformation Products in Sea Water

International Nuclear Information System (INIS)

Saveleva, E. I.; Koryagina, N. L.; Radilov, A. S.; Khlebnikova, N. S.; Khrustaleva, V. S.

2007-01-01

A package of chemical analytical procedures was developed for the detection of products indicative of the presence of damped chemical weapons in the Baltic Sea. The principal requirements imposed upon the procedures were the following: high sensitivity, reliable identification of target compounds, wide range of components covered by survey analysis, and lack of interferences from sea salts. Thiodiglycol, a product of hydrolysis of sulfur mustard reportedly always detected in the sites of damping chemical weapons in the Baltic Sea, was considered the principal marker. We developed a high-sensitivity procedure for the determination of thiodiglycol in sea water, involving evaporation of samples to dryness in a vacuum concentrator, followed by tert-butyldimethylsilylation of the residue and GCMS analysis in the SIM mode with meta-fluorobenzoic acid as internal reference. The detection limit of thiodiglycol was 0.001 mg/l, and the procedure throughput was up to 30 samples per day. The same procedure, but with BSTFA as derivatizing agent instead of MTBSTFA, was used for preparing samples for survey analysis of nonvolatile components. In this case, full mass spectra were measured in the GCMS analysis. The use of BSTFA was motivated by the fact that trimethylsilyl derivatives are much wider represented in electronic mass spectral databases. The identification of sulfur mustard, volatile transformation products of sulfur mustard and lewisite, as well as chloroacetophenone in sea water was performed by means of GCMS in combination with SPME. The survey GC-MS analysis was focused on the identification of volatile and nonvolatile toxic chemicals whose mass spectra are included in the OPCW database (3219 toxic chemicals, precursors, and transformation products) with the use of AMDIS software (version 2.62). Using 2 GC-MS instruments, we could perform the survey analysis for volatile and nonvolatile components of up to 20 samples per day. Thus, the package of three procedures

Quality analysis of commercial samples of Ziziphi spinosae semen (suanzaoren by means of chromatographic fingerprinting assisted by principal component analysis

Directory of Open Access Journals (Sweden)

Shuai Sun

2014-06-01

Full Text Available Due to the scarcity of resources of Ziziphi spinosae semen (ZSS, many inferior goods and even adulterants are generally found in medicine markets. To strengthen the quality control, HPLC fingerprint common pattern established in this paper showed three main bioactive compounds in one chromatogram simultaneously. Principal component analysis based on DAD signals could discriminate adulterants and inferiorities. Principal component analysis indicated that all samples could be mainly regrouped into two main clusters according to the first principal component (PC1, redefined as Vicenin II and the second principal component (PC2, redefined as zizyphusine. PC1 and PC2 could explain 91.42% of the variance. Content of zizyphusine fluctuated more greatly than that of spinosin, and this result was also confirmed by the HPTLC result. Samples with low content of jujubosides and two common adulterants could not be used equivalently with authenticated ones in clinic, while one reference standard extract could substitute the crude drug in pharmaceutical production. Giving special consideration to the well-known bioactive saponins but with low response by end absorption, a fast and cheap HPTLC method for quality control of ZSS was developed and the result obtained was commensurate well with that of HPLC analysis. Samples having similar fingerprints to HPTLC common pattern targeting at saponins could be regarded as authenticated ones. This work provided a faster and cheaper way for quality control of ZSS and laid foundation for establishing a more effective quality control method for ZSS. Keywords: Adulterant, Common pattern, Principal component analysis, Quality control, Ziziphi spinosae semen

Setting Instructional Expectations: Patterns of Principal Leadership for Middle School Mathematics

Science.gov (United States)

Katterfeld, Karin

2013-01-01

Principal instructional leadership has been found to support improved instruction. However, the methods through which principal leadership influences classroom instruction are less clear. This study investigates how principals' leadership may predict the expectations that mathematics teachers perceive for classroom practice. Results from a…

A Principal-Agent Analysis of the Family: Implications for the Welfare State

OpenAIRE

Munro, Lauchlan

1999-01-01

The principal-agent literature has focussed on situations where both principal and agent are assumed to be capable of defining and defending their own interests. The principal-agent literature has thus ignored an important set of cases where the principal is incapable of acting on her own behalf, and so is assigned an agent by law or custom. Such cases account for around 40% of humanity and for a similarly substantial proportion of all principal-agent interactions. This paper applies principa...

Targeting membrane-bound viral RNA synthesis reveals potent inhibition of diverse coronaviruses including the middle East respiratory syndrome virus.

Directory of Open Access Journals (Sweden)

Anna Lundin

2014-05-01

Full Text Available Coronaviruses raise serious concerns as emerging zoonotic viruses without specific antiviral drugs available. Here we screened a collection of 16671 diverse compounds for anti-human coronavirus 229E activity and identified an inhibitor, designated K22, that specifically targets membrane-bound coronaviral RNA synthesis. K22 exerts most potent antiviral activity after virus entry during an early step of the viral life cycle. Specifically, the formation of double membrane vesicles (DMVs, a hallmark of coronavirus replication, was greatly impaired upon K22 treatment accompanied by near-complete inhibition of viral RNA synthesis. K22-resistant viruses contained substitutions in non-structural protein 6 (nsp6, a membrane-spanning integral component of the viral replication complex implicated in DMV formation, corroborating that K22 targets membrane bound viral RNA synthesis. Besides K22 resistance, the nsp6 mutants induced a reduced number of DMVs, displayed decreased specific infectivity, while RNA synthesis was not affected. Importantly, K22 inhibits a broad range of coronaviruses, including Middle East respiratory syndrome coronavirus (MERS-CoV, and efficient inhibition was achieved in primary human epithelia cultures representing the entry port of human coronavirus infection. Collectively, this study proposes an evolutionary conserved step in the life cycle of positive-stranded RNA viruses, the recruitment of cellular membranes for viral replication, as vulnerable and, most importantly, druggable target for antiviral intervention. We expect this mode of action to serve as a paradigm for the development of potent antiviral drugs to combat many animal and human virus infections.

Principal Leadership in the Accountability Era: Influence of Expanding Job Responsibilities on Functional Work Performance, Stress Management, and Overall Job Satisfaction

Science.gov (United States)

Andreyko, Tammy A.

2010-01-01

This study examined the relationship of stress, burnout, and coping strategies among middle school principals in Western Pennsylvania. This study assessed coping skill preferences among middle school principals, especially regarding their age, gender, marital status, experience, and school enrollment. A review of the literature included studies…

Targeting Prolyl Peptidases in Triple-Negative Breast Cancer

Science.gov (United States)

2017-02-01

ABSTRACT Triple negative breast cancer (TNBC) is an aggressive sub-type with limited treatment options and poor prognosis. The most life -threatening... negative feedback loops within the pathway limit their effectiveness . For example, AKT inhibitors cause increased expression of IGF1R/ErbB3 and, as a...AWARD NUMBER: W81XWH-16-1-0025 TITLE: Targeting Prolyl Peptidases in Triple- Negative Breast Cancer PRINCIPAL INVESTIGATOR: Carl G. Maki, PhD

A Tannakian approach to dimensional reduction of principal bundles

Science.gov (United States)

Álvarez-Cónsul, Luis; Biswas, Indranil; García-Prada, Oscar

2017-08-01

Let P be a parabolic subgroup of a connected simply connected complex semisimple Lie group G. Given a compact Kähler manifold X, the dimensional reduction of G-equivariant holomorphic vector bundles over X × G / P was carried out in Álvarez-Cónsul and García-Prada (2003). This raises the question of dimensional reduction of holomorphic principal bundles over X × G / P. The method of Álvarez-Cónsul and García-Prada (2003) is special to vector bundles; it does not generalize to principal bundles. In this paper, we adapt to equivariant principal bundles the Tannakian approach of Nori, to describe the dimensional reduction of G-equivariant principal bundles over X × G / P, and to establish a Hitchin-Kobayashi type correspondence. In order to be able to apply the Tannakian theory, we need to assume that X is a complex projective manifold.

PRINCIPAL COMPONENT ANALYSIS (PCA DAN APLIKASINYA DENGAN SPSS

Directory of Open Access Journals (Sweden)

Hermita Bus Umar

2009-03-01

Full Text Available PCA (Principal Component Analysis are statistical techniques applied to a single set of variables when the researcher is interested in discovering which variables in the setform coherent subset that are relativity independent of one another.Variables that are correlated with one another but largely independent of other subset of variables are combined into factors. The Coals of PCA to which each variables is explained by each dimension. Step in PCA include selecting and mean measuring a set of variables, preparing the correlation matrix, extracting a set offactors from the correlation matrixs. Rotating the factor to increase interpretabilitv and interpreting the result.

Principal results of 'DEWAM' project implementation, Russian Federation

International Nuclear Information System (INIS)

Nechaev, A.F.

2002-01-01

This overview summarizes the key results of the four-year project 'Decontamination and Waste Management in the Course of Research Reactors Decommissioning' carried out within the framework of the IAEA's CRP 'Decommissioning Techniques for Research Reactors'. The project included two principal components: (1) info-analytical studies and development of a database system, and (2) research and development in the areas of decontamination and waste management technologies applicable to decommissioning. Details of the work are expounded in 29 publications and annual Progress Reports; the results of the study are used in corresponding university courses; and innovative technologies for radwaste processing and environmental restoration are planned to be introduced into practice. (author)

Longitudinal functional principal component modelling via Stochastic Approximation Monte Carlo

KAUST Repository

Martinez, Josue G.

2010-06-01

The authors consider the analysis of hierarchical longitudinal functional data based upon a functional principal components approach. In contrast to standard frequentist approaches to selecting the number of principal components, the authors do model averaging using a Bayesian formulation. A relatively straightforward reversible jump Markov Chain Monte Carlo formulation has poor mixing properties and in simulated data often becomes trapped at the wrong number of principal components. In order to overcome this, the authors show how to apply Stochastic Approximation Monte Carlo (SAMC) to this problem, a method that has the potential to explore the entire space and does not become trapped in local extrema. The combination of reversible jump methods and SAMC in hierarchical longitudinal functional data is simplified by a polar coordinate representation of the principal components. The approach is easy to implement and does well in simulated data in determining the distribution of the number of principal components, and in terms of its frequentist estimation properties. Empirical applications are also presented.

Targeting the Brain with Nanomedicine.

Science.gov (United States)

Rueda, Felix; Cruz, Luis J

2017-01-01

Herein, we review innovative nanomedicine-based approaches for treating, preventing and diagnosing neurodegenerative diseases. We focus on nanoscale systems such as polymeric nanoparticles (NPs), liposomes, micelles and other vehicles (e.g. dendrimers, nanogels, nanoemulsions and nanosuspensions) for targeted delivery of bioactive molecules to the brain. To ensure maximum selectivity for optimal therapeutic or diagnostic results, researchers must employ delivery systems that are non-toxic, biodegradable and biocompatible. This entails: (i) use of "safe" materials, such as polymers or lipids; (ii) targeting to the brain and, specifically, to the desired active site within the brain; (iii) controlled release of the loaded agent; and (iv) use of agents that, once released into the brain, will exhibit the desired pharmacologic activity. Here, we explore the design and preclinical use of representative delivery systems that have been proposed to date. We then analyze the principal challenges that have delayed clinical application of these and other approaches. Lastly, we look at future developments in this area, addressing the needs for increased penetration of the blood brain barrier (BBB), enhanced targeting of specific brain sites, improved therapeutic efficacy and lower neurotoxicity. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.org.

Probabilistic Principal Component Analysis for Metabolomic Data.

LENUS (Irish Health Repository)

Nyamundanda, Gift

2010-11-23

Abstract Background Data from metabolomic studies are typically complex and high-dimensional. Principal component analysis (PCA) is currently the most widely used statistical technique for analyzing metabolomic data. However, PCA is limited by the fact that it is not based on a statistical model. Results Here, probabilistic principal component analysis (PPCA) which addresses some of the limitations of PCA, is reviewed and extended. A novel extension of PPCA, called probabilistic principal component and covariates analysis (PPCCA), is introduced which provides a flexible approach to jointly model metabolomic data and additional covariate information. The use of a mixture of PPCA models for discovering the number of inherent groups in metabolomic data is demonstrated. The jackknife technique is employed to construct confidence intervals for estimated model parameters throughout. The optimal number of principal components is determined through the use of the Bayesian Information Criterion model selection tool, which is modified to address the high dimensionality of the data. Conclusions The methods presented are illustrated through an application to metabolomic data sets. Jointly modeling metabolomic data and covariates was successfully achieved and has the potential to provide deeper insight to the underlying data structure. Examination of confidence intervals for the model parameters, such as loadings, allows for principled and clear interpretation of the underlying data structure. A software package called MetabolAnalyze, freely available through the R statistical software, has been developed to facilitate implementation of the presented methods in the metabolomics field.

Burnout And Lifestyle Of Principals And Entrepreneurs

Directory of Open Access Journals (Sweden)

Jasna Lavrenčič

2014-12-01

Full Text Available Research Question (RQ: What kind of lifestyle do the principals and entrepreneurs lead? Does the lifestyle of principals and entrepreneurs influence burnout? Purpose: To find out, based on the results of a questionnaire, what kind of lifestyle both researched groups lead. Does lifestyle have an influence on the occurrence of the phenomenon of burnout. Method: We used the method of data collection by questionnaire. Acquired data were analyzed using SPSS, descriptive and inference statistics. Results: Results showed, that both groups lead a similar lifestyle and that lifestyle influences burnout with principals, as well as entrepreneurs. Organization: School principals and entrepreneurs are the heads of individual organizations or companies, the goal of which is success. To be successful in their work, they must adapt their lifestyle, which can be healthy or unhealthy. If their lifestyle is unhealthy, it can lead to burnout. Society: With results of the questionnaire we would like to answer the question about the lifestyle of both groups and its influence on the occurrence of burnout. Originality: The study of lifestyle and the occurrence of burnout in these two groups is the first study in this area. Limitations/Future Research: In continuation, research groups could be submitted to the research fields of effort physiology and tracking of certain haematological parameters, such as cholesterol, blood sugar and stress hormones - adrenaline, noradrenalin, cortisol. Thus, we could carry out an even more in depth research of the connection between lifestyle and burnout.

26 CFR 301.6226(a)-1 - Principal place of business of partnership.

Science.gov (United States)

2010-04-01

... 26 Internal Revenue 18 2010-04-01 2010-04-01 false Principal place of business of partnership. 301... Principal place of business of partnership. (a) In general. The principal place of a partnership's business... partnership items may be filed is its principal place of business as of the date the petition is filed. (b...

Toward Instructional Leadership: Principals' Perceptions of Large-Scale Assessment in Schools

Science.gov (United States)

Prytula, Michelle; Noonan, Brian; Hellsten, Laurie

2013-01-01

This paper describes a study of the perceptions that Saskatchewan school principals have regarding large-scale assessment reform and their perceptions of how assessment reform has affected their roles as principals. The findings revealed that large-scale assessments, especially provincial assessments, have affected the principal in Saskatchewan…

Instructional Leadership Responsibilities of Assistant Principals in Large Texas High Schools

Science.gov (United States)

Howard-Schwind, Michelle

2010-01-01

The purpose of this study was to determine the extent secondary assistant principals in large Texas high schools demonstrate behaviors consistent with what the literature describes as instructional leadership. Three hundred seventy principals and assistant principals of large Texas high schools participated in this study. The Principal…

Comment 2 on workshop in political institutions - principal-agent relationships

International Nuclear Information System (INIS)

Feeny, D.

1992-01-01

In recent decades, economic analysis has been extended to situations in which there are important asymmetries of information between actors. One important class of these situations are principal-agent relationships, in which one party, the agent, acts on behalf of the other, the principal. In such situations of incomplete and asymmetric information (in which the agent may be better informed than the principal), is it possible to devise mechanisms to ensure that the agent acts in the best interests of the principal? How can we construct relationships so that physicians act in the best interests of patients, lawyer in the best interests of their clients, or public officials in the best interests of their constituents?

The experiences of female principals on curriculum leadership in ...

African Journals Online (AJOL)

Gender and Behaviour ... women have managed curriculum implementation in secondary schools in order to inform both policy makers, school principals and scholars of gender studies about good practices from ... The study found that: One, these principals possessed social skills, such as warmth and strong relationships.

Collusion and Renegotiation in a Principal-Supervisor-Agent Relationship

NARCIS (Netherlands)

Strausz, R.G.

1995-01-01

This paper describes a principal-agent relationship with a supervisor who has information about the agent. The agent and the supervisor have the possibility to collude and misinform the principal. From the literature we know that there exists an optimal contract which excludes collusion in

The potential of AR-V7 as a therapeutic target.

Science.gov (United States)

Uo, Takuma; Plymate, Stephen R; Sprenger, Cynthia C

2018-03-01

The androgen receptor variant AR-V7 is gaining attention as a potential predictive marker for as well as one of the resistance mechanisms to the most current anti-androgen receptor (AR) therapies in castration-resistant prostate cancer (CRPC). Accordingly, development of next-generation drugs that directly or indirectly target AR-V7 signaling is urgently needed. Areas covered: We review proposed mechanisms of drug resistance in relation to AR-V7 status, the mechanisms of generation of AR-V7, and its transcriptome, cistrome, and interactome. Pharmacological agents that interfere with these processes are being developed to counteract pan AR and AR-V7-specific signaling. Also, we address the current status of the preclinical and clinical studies targeting AR-V7 signaling. Expert opinion: AR-V7 is considered a true therapeutic target, however, it remains to be determined if AR-V7 is a principal driver or merely a bystander requiring heterodimerization with co-expressed full-length AR or other variants to drive CRPC progression. While untangling AR-V7 biology, multiple strategies are being developed to counteract drug resistance, including selective blockade of AR-V7 signaling as well as inhibition of pan-AR signaling. Ideally anti-AR therapies will be combined with agents preventing activation and enrichment of AR negative tumor cells that are otherwise depressed by AR activity axis.

Constrained principal component analysis and related techniques

CERN Document Server

Takane, Yoshio

2013-01-01

In multivariate data analysis, regression techniques predict one set of variables from another while principal component analysis (PCA) finds a subspace of minimal dimensionality that captures the largest variability in the data. How can regression analysis and PCA be combined in a beneficial way? Why and when is it a good idea to combine them? What kind of benefits are we getting from them? Addressing these questions, Constrained Principal Component Analysis and Related Techniques shows how constrained PCA (CPCA) offers a unified framework for these approaches.The book begins with four concre

Teachers' Perspectives of the Principals' Invitational Leadership Behaviors, Teacher Job Satisfaction and Principal Effectiveness in High-Poverty Rural Elementary Schools

Science.gov (United States)

Younis, Matthew Christopher Zadin

2017-01-01

The purpose of this study was to examine the impact of Invitational Leadership behaviors on school teacher satisfaction, teacher perceptions of the school principal's performance, and to identify if there was a difference between the levels of inviting behaviors of principals at high-achieving and low-achieving rural schools in North Carolina. The…

Stepping Stones: Principal Career Paths and School Outcomes. Working Paper 58

Science.gov (United States)

Beteille, Tara; Kalogrides, Demetra; Loeb, Susanna

2011-01-01

Principals tend to prefer working in schools with higher-achieving students from more advantaged socioeconomic backgrounds. Principals often use schools with many poor or low-achieving students as stepping stones to what they view as more desirable assignments. District leadership can also exacerbate principal turnover by implementing policies…

Assessing Principals' Quality Assurance Strategies in Osun State Secondary Schools, Nigeria

Science.gov (United States)

Fasasi, Yunus Adebunmi; Oyeniran, Saheed

2014-01-01

This paper examined principals' quality assurance strategies in secondary schools in Osun State, Nigeria. The study adopted a descriptive survey research design. Stratified random sampling technique was used to select 10 male and 10 female principals, and 190 male and190 female teachers. "Secondary School Principal Quality Assurance…

Career Status of Secondary Principals in Small Schools in the Southwest.

Science.gov (United States)

Seifert, Edward H.

1985-01-01

A random sample of 559 secondary small school principals in Arkansas, Colorado, New Mexico, Oklahoma, and Texas revealed that 73 percent of the principals were actively seeking new positions or were leaving school administration. The findings have implications for selection procedures, salary/fringe benefit packages, principal autonomy, evaluation…

School Principals' Assumptions about Human Nature: Implications for Leadership in Turkey

Science.gov (United States)

Sabanci, Ali

2008-01-01

This article considers principals' assumptions about human nature in Turkey and the relationship between the assumptions held and the leadership style adopted in schools. The findings show that school principals hold Y-type assumptions and prefer a relationship-oriented style in their relations with assistant principals. However, both principals…

Regularized principal covariates regression and its application to finding coupled patterns in climate fields

Science.gov (United States)

Fischer, M. J.

2014-02-01

There are many different methods for investigating the coupling between two climate fields, which are all based on the multivariate regression model. Each different method of solving the multivariate model has its own attractive characteristics, but often the suitability of a particular method for a particular problem is not clear. Continuum regression methods search the solution space between the conventional methods and thus can find regression model subspaces that mix the attractive characteristics of the end-member subspaces. Principal covariates regression is a continuum regression method that is easily applied to climate fields and makes use of two end-members: principal components regression and redundancy analysis. In this study, principal covariates regression is extended to additionally span a third end-member (partial least squares or maximum covariance analysis). The new method, regularized principal covariates regression, has several attractive features including the following: it easily applies to problems in which the response field has missing values or is temporally sparse, it explores a wide range of model spaces, and it seeks a model subspace that will, for a set number of components, have a predictive skill that is the same or better than conventional regression methods. The new method is illustrated by applying it to the problem of predicting the southern Australian winter rainfall anomaly field using the regional atmospheric pressure anomaly field. Regularized principal covariates regression identifies four major coupled patterns in these two fields. The two leading patterns, which explain over half the variance in the rainfall field, are related to the subtropical ridge and features of the zonally asymmetric circulation.

A Schoolwide Discipline Plan That Empowers Teachers and Gives Principals Time for Instructional Leadership.

Science.gov (United States)

Borelli, Jan

1997-01-01

A high school principal explains her strategy for turning around a disorderly, gang-ridden middle school. Her discipline plan's success hinged on developing schoolwide expectations for behavior, developing positive consequences, compiling a list of unacceptable behaviors, and empowering teachers to administer consequences, including contacting…

The Motivating Language of Principals: A Sequential Transformative Strategy

Science.gov (United States)

Holmes, William Tobias

2012-01-01

This study implemented a Sequential Transformative Mixed Methods design with teachers (as recipients) and principals (to give voice) in the examination of principal talk in two different school accountability contexts (Continuously Improving and Continuously Zigzag) using the conceptual framework of Motivating Language Theory. In phase one,…

Empowering Teachers: Characteristics, Strategies, and Practices of Successful Principals

Science.gov (United States)

Ellis, Cailin Patrice

2012-01-01

This study implemented an exploratory mixed-methods design to better understand how the characteristics of a principal, specifically the strategies, behaviors, and actions, lead to the perception of empowerment as perceived by the teachers themselves. An expert panel identified three "highly successful" principals assigned to elementary…

School Uniforms: Guidelines for Principals.

Science.gov (United States)

Essex, Nathan L.

2001-01-01

Principals desiring to develop a school-uniform policy should involve parents, teachers, community leaders, and student representatives; beware restrictions on religious and political expression; provide flexibility and assistance for low-income families; implement a pilot program; align the policy with school-safety issues; and consider legal…

Getting from Here to There: The Roles of Policy Makers and Principals in Increasing Science Teacher Quality

Science.gov (United States)

Shen, Ji; Gerard, Libby; Bowyer, Jane

2010-04-01

In this study we investigate how federal and state policy makers, and school principals are working to improve science teacher quality. Interviews, focused discussions, and policy documents serve as the primary data source. Findings suggest that both policy makers and principals prioritize increasing incentives for teachers entering the science teaching profession, providing professional development for new teachers, and using students’ data to evaluate and improve instruction. Differences between the two leadership groups emerged in terms of the grain size and practicality of their concerns. Our findings indicate that the complexity of educational challenges to improve science teacher quality call for the co-construction of policy by multiple constituent groups including school principals, federal and state policy makers, and science education researchers.

Financial and Managerial Accounting for School Administrators: Superintendents, School Business Administrators, and Principals.

Science.gov (United States)

Everett, R. E.; And Others

This book updates the classic text "Public School Fund Accounting Principles and Procedures" (Tidwell 1960). The book is designed to be used primarily as a textbook at the graduate level with students training to be school administrators, school business administrators, or principals. A list of topics covered include an overview of school…

The principal radionuclides in high level radioactive waste management

International Nuclear Information System (INIS)

Mulyanto

1998-01-01

The principal radionuclides in high level radioactive waste management. The selection of the principal radionuclides in the high level waste (HLW) management was developed in order to improve the disposal scenario of HLW. In this study the unified criteria for selection of the principal radionuclides were proposed as; (1) the value of hazard index estimated by annual limit of intake (ALI) for long-term tendency,(2) the relative dose factor related to adsorbed migration rate transferred by ground water, and (3) heat generation in the repository. From this study it can be concluded that the principal radionuclides in the HLW management were minor actinide (MA=Np, Am, Cm, etc), Tc, I, Cs and Sr, based on the unified basic criteria introduced in this study. The remaining short-lived fission product (SLFPs), after the selected nuclides are removed, should be immobilized and solidified in a glass matrix. Potential risk due to the remaining SLFPs can be lower than that of uranium ore after about 300 year. (author)

Robust Small Target Co-Detection from Airborne Infrared Image Sequences.

Science.gov (United States)

Gao, Jingli; Wen, Chenglin; Liu, Meiqin

2017-09-29

In this paper, a novel infrared target co-detection model combining the self-correlation features of backgrounds and the commonality features of targets in the spatio-temporal domain is proposed to detect small targets in a sequence of infrared images with complex backgrounds. Firstly, a dense target extraction model based on nonlinear weights is proposed, which can better suppress background of images and enhance small targets than weights of singular values. Secondly, a sparse target extraction model based on entry-wise weighted robust principal component analysis is proposed. The entry-wise weight adaptively incorporates structural prior in terms of local weighted entropy, thus, it can extract real targets accurately and suppress background clutters efficiently. Finally, the commonality of targets in the spatio-temporal domain are used to construct target refinement model for false alarms suppression and target confirmation. Since real targets could appear in both of the dense and sparse reconstruction maps of a single frame, and form trajectories after tracklet association of consecutive frames, the location correlation of the dense and sparse reconstruction maps for a single frame and tracklet association of the location correlation maps for successive frames have strong ability to discriminate between small targets and background clutters. Experimental results demonstrate that the proposed small target co-detection method can not only suppress background clutters effectively, but also detect targets accurately even if with target-like interference.

A critical review of principal traffic noise models: Strategies and implications

Energy Technology Data Exchange (ETDEWEB)

Garg, Naveen, E-mail: ngarg@mail.nplindia.ernet.in [Apex Level Standards and Industrial Metrology Division, CSIR-National Physical Laboratory, New Delhi 110012 (India); Department of Mechanical, Production and Industrial Engineering, Delhi Technological University, Delhi 110042 (India); Maji, Sagar [Department of Mechanical, Production and Industrial Engineering, Delhi Technological University, Delhi 110042 (India)

2014-04-01

The paper presents an exhaustive comparison of principal traffic noise models adopted in recent years in developed nations. The comparison is drawn on the basis of technical attributes including source modelling and sound propagation algorithms. Although the characterization of source in terms of rolling and propulsion noise in conjunction with advanced numerical methods for sound propagation has significantly reduced the uncertainty in traffic noise predictions, the approach followed is quite complex and requires specialized mathematical skills for predictions which is sometimes quite cumbersome for town planners. Also, it is sometimes difficult to follow the best approach when a variety of solutions have been proposed. This paper critically reviews all these aspects pertaining to the recent models developed and adapted in some countries and also discusses the strategies followed and implications of these models. - Highlights: • Principal traffic noise models developed are reviewed. • Sound propagation algorithms used in traffic noise models are compared. • Implications of models are discussed.

Detecting Genomic Signatures of Natural Selection with Principal Component Analysis: Application to the 1000 Genomes Data.

Science.gov (United States)

Duforet-Frebourg, Nicolas; Luu, Keurcien; Laval, Guillaume; Bazin, Eric; Blum, Michael G B

2016-04-01

To characterize natural selection, various analytical methods for detecting candidate genomic regions have been developed. We propose to perform genome-wide scans of natural selection using principal component analysis (PCA). We show that the common FST index of genetic differentiation between populations can be viewed as the proportion of variance explained by the principal components. Considering the correlations between genetic variants and each principal component provides a conceptual framework to detect genetic variants involved in local adaptation without any prior definition of populations. To validate the PCA-based approach, we consider the 1000 Genomes data (phase 1) considering 850 individuals coming from Africa, Asia, and Europe. The number of genetic variants is of the order of 36 millions obtained with a low-coverage sequencing depth (3×). The correlations between genetic variation and each principal component provide well-known targets for positive selection (EDAR, SLC24A5, SLC45A2, DARC), and also new candidate genes (APPBPP2, TP1A1, RTTN, KCNMA, MYO5C) and noncoding RNAs. In addition to identifying genes involved in biological adaptation, we identify two biological pathways involved in polygenic adaptation that are related to the innate immune system (beta defensins) and to lipid metabolism (fatty acid omega oxidation). An additional analysis of European data shows that a genome scan based on PCA retrieves classical examples of local adaptation even when there are no well-defined populations. PCA-based statistics, implemented in the PCAdapt R package and the PCAdapt fast open-source software, retrieve well-known signals of human adaptation, which is encouraging for future whole-genome sequencing project, especially when defining populations is difficult. © The Author(s) 2015. Published by Oxford University Press on behalf of the Society for Molecular Biology and Evolution.

Knowledge and Professional Development for Principals Leading Linguistic Communities in Schools

Science.gov (United States)

Vidal-Butler, Stacey Lynn

2017-01-01

The role of the school principal is demanding in a variety of ways. School principals are faced with the daily challenge of balancing their roles of site manager and instructional leader. This study examined and identified the knowledge and learning opportunities school principals rely upon to lead schools, particularly those that lead schools…

The Job Realities of Beginning and Experienced Assistant Principals

Science.gov (United States)

Barnett, Bruce G.; Shoho, Alan R.; Oleszewski, Ashley M.

2012-01-01

This study examined the perceptions of a cross section of new and experienced assistant principals regarding the realities of their jobs. Findings indicated that their challenges pertain to workload and task management, conflicts with adults and students, and curriculum and instruction issues. Novice and experienced assistant principals' responses…

Ecstasy of Emptiness? Reflections of a Retired School Principal.

Science.gov (United States)

Azzara, Judith R.

2001-01-01

A retired elementary principal who was actively tied to her community for decades explains how to put a positive spin on retirement. New retirees should treasure their gifts and talents, develop new ones, take advantage of travel opportunities, mentor a new principal, and/or go back to college. (MLH)

75 FR 82236 - Principal Trades with Certain Advisory Clients

Science.gov (United States)

2010-12-30

... 3235-AJ96 Principal Trades with Certain Advisory Clients AGENCY: Securities and Exchange Commission... certain of their advisory clients. The amendment extends the date on which rule 206(3)- 3T will sunset... a principal capacity in transactions with certain of their advisory clients.\\1\\ In December 2009, we...

Rural Rides in Queensland: Travels with Novice Teaching Principals

Science.gov (United States)

Clarke, Simon; Stevens, Elizabeth; Wildy, Helen

2006-01-01

This article is concerned with the nature of novice teaching principals' interactions in Queensland rural communities. Stories selected from case accounts are used to provide insights into the teaching principals' interrelationship with the community. The article concludes with a discussion of some implications for practice suggested by these…

The Technology Principal: To Be or Not to Be?

Science.gov (United States)

Anthony, Anika Ball; Patravanich, Supawaree

2014-01-01

This case provides principal licensure candidates a strategic perspective on leading and managing educational technology initiatives. It presents issues related to vision setting, planning, implementation, organizational structure, and decision making. The case narrative is presented from the perspective of a principal, but it can also be used to…

Importing a Culture of Success Via a Strong Principal.

Science.gov (United States)

Reavis, Charles A.; Vinson, David; Fox, Richard

1999-01-01

Examines how a new principal at a historically low-performing high school brought about changes in the school culture and in student achievement. Describes how the principal emphasized achievement at the highest levels through heroes and heroines, rites and rituals, stories, governance and leadership, symbols, enforcing expectations, and serving…

Stress and PTSD Mechanisms as Targets for Pharmacotherapy of Alcohol Abuse, Addiction and Relapse

Science.gov (United States)

2017-10-01

AWARD NUMBER: W81XWH-13-1-0126 TITLE: Stress and PTSD Mechanisms as Targets for Pharmacotherapy of Alcohol Abuse, Addiction and Relapse PRINCIPAL...10/27/2017 2. REPORT TYPE Annual 3. DATES COVERED 30 Sep 2016 — 29 Sep 2017 4. TITLE AND SUBTITLE Stress and PTSD Mechanisms as Targets for...insights into mechanism; (2) suppression of noradrenergic signaling decreases alcohol drinking in rats with a history of traumatic stress , but not in

Use of an activated beta-catenin to identify Wnt pathway target genes in caenorhabditis elegans, including a subset of collagen genes expressed in late larval development.

Science.gov (United States)

Jackson, Belinda M; Abete-Luzi, Patricia; Krause, Michael W; Eisenmann, David M

2014-04-16

The Wnt signaling pathway plays a fundamental role during metazoan development, where it regulates diverse processes, including cell fate specification, cell migration, and stem cell renewal. Activation of the beta-catenin-dependent/canonical Wnt pathway up-regulates expression of Wnt target genes to mediate a cellular response. In the nematode Caenorhabditis elegans, a canonical Wnt signaling pathway regulates several processes during larval development; however, few target genes of this pathway have been identified. To address this deficit, we used a novel approach of conditionally activated Wnt signaling during a defined stage of larval life by overexpressing an activated beta-catenin protein, then used microarray analysis to identify genes showing altered expression compared with control animals. We identified 166 differentially expressed genes, of which 104 were up-regulated. A subset of the up-regulated genes was shown to have altered expression in mutants with decreased or increased Wnt signaling; we consider these genes to be bona fide C. elegans Wnt pathway targets. Among these was a group of six genes, including the cuticular collagen genes, bli-1 col-38, col-49, and col-71. These genes show a peak of expression in the mid L4 stage during normal development, suggesting a role in adult cuticle formation. Consistent with this finding, reduction of function for several of the genes causes phenotypes suggestive of defects in cuticle function or integrity. Therefore, this work has identified a large number of putative Wnt pathway target genes during larval life, including a small subset of Wnt-regulated collagen genes that may function in synthesis of the adult cuticle.

Teachers' Perspectives on Principal Mistreatment

Science.gov (United States)

Blase, Joseph; Blase, Jo

2006-01-01

Although there is some important scholarly work on the problem of workplace mistreatment/abuse, theoretical or empirical work on abusive school principals is nonexistent. Symbolic interactionism was the theoretical structure for the present study. This perspective on social research is founded on three primary assumptions: (1) individuals act…

Attitudes of school principals and teachers towards computers : does it matter what they think?

NARCIS (Netherlands)

Pelgrum, W.J.

1993-01-01

In 1989, the IEA Computers in Education study collected data on computer use in elementary, lower- and upper secondary schools in 22 educational systems. The data collection included attitude measures for principals of computer-using as well as non-using schools and for teachers of computer

Principal Perceptions of the Effectiveness of University Educational Leadership Preparation and Professional Learning

Science.gov (United States)

Johnson, Arvin D.

2016-01-01

Principals and assistant principals currently serving in Florida and Georgia school districts were surveyed about their perceptions of university educational leadership preparation and professional learning. The results revealed that many principals and assistant principals agreed that university educational leadership preparation programs…

A New "Principal Principle" (#14) of Physical Activity Education Is Emerging

Science.gov (United States)

Zeigler, Earle F.

2011-01-01

There is every reason to believe that a new "principal principle" of physical activity education is emerging. In this article, the author talks about the new "principal principle"(#14) of physical education. Revisiting a historical milestone in the field's history to explain the origin of the term "principal principle," Dr. Arthur H. Steinhaus,…

An evaluation capacity building toolkit for principal investigators of undergraduate research experiences: A demonstration of transforming theory into practice.

Science.gov (United States)

Rorrer, Audrey S

2016-04-01

This paper describes the approach and process undertaken to develop evaluation capacity among the leaders of a federally funded undergraduate research program. An evaluation toolkit was developed for Computer and Information Sciences and Engineering(1) Research Experiences for Undergraduates(2) (CISE REU) programs to address the ongoing need for evaluation capacity among principal investigators who manage program evaluation. The toolkit was the result of collaboration within the CISE REU community with the purpose being to provide targeted instructional resources and tools for quality program evaluation. Challenges were to balance the desire for standardized assessment with the responsibility to account for individual program contexts. Toolkit contents included instructional materials about evaluation practice, a standardized applicant management tool, and a modulated outcomes measure. Resulting benefits from toolkit deployment were having cost effective, sustainable evaluation tools, a community evaluation forum, and aggregate measurement of key program outcomes for the national program. Lessons learned included the imperative of understanding the evaluation context, engaging stakeholders, and building stakeholder trust. Results from project measures are presented along with a discussion of guidelines for facilitating evaluation capacity building that will serve a variety of contexts. Copyright © 2016. Published by Elsevier Ltd.

Principal permeability determination from multiple horizontal well tests

Energy Technology Data Exchange (ETDEWEB)

Economides, M. [Texas A and M Univ., TX (United States); Munoz, A.; Ehlig-Economides, C.

1998-12-31

A method for obtaining principal permeability magnitudes and direction that requires only the linear flow regime from transient tests in three horizontal wells oriented in three distinct and arbitrary directions, is described. Well design optimization strategies require knowledge of both the principal permeability orientation as well as the horizontal permeability magnitudes. When the degree of horizontal permeability anisotropy (i.e. permeability in the bedding plane with respect to direction) is significant, the productivity of a long horizontal well will depend greatly on its direction, especially when the well is first brought into production. Productivities have been found to deviate substantially among wells in the same reservoir and this deviation has been attributed to differences in well orientation. In view of this fact, measuring permeability anisotropy becomes a compelling necessity. The success of the proposed method is illustrated by a case study in which the principal permeability magnitudes and direction from three wells were used to predict the productivity of a fourth well within 10 per cent. Use of the computed principal permeabilities from the case study, it was possible to forecast the cumulative production to show the significance of well trajectory optimization on the discounted cash flow and the net present value. 20 refs., 3 figs.

Invisible Barriers: The Loneliness of School Principals at Turkish ...

African Journals Online (AJOL)

Psychological insight is the notion that all participants agreed on and emphasised when asked to offer a definition of loneliness at schools. Participants also agreed on the fact that the organisational climate at Turkish schools represented the most significant reason for principals' loneliness at work. The school principals that ...

40 CFR 14.12 - Principal types of unallowable claims.

Science.gov (United States)

2010-07-01

... 40 Protection of Environment 1 2010-07-01 2010-07-01 false Principal types of unallowable claims... PERSONAL PROPERTY CLAIMS § 14.12 Principal types of unallowable claims. Claims that ordinarily will not be... valid appraisal or authentication with the carrier prior to shipment of the item; (d) Loss of bankbooks...

Teacher-Principal Race and Teacher Satisfaction over Time, Region

Science.gov (United States)

Viano, Samantha L.; Hunter, Seth B.

2017-01-01

Purpose: The purpose of this paper is to replicate prior findings on teacher-principal race congruence and teacher job satisfaction and extend the literature by investigating trends over time and if the relationship between race congruence and teacher job satisfaction differs by principal race and region. Design/methodology/approach: The study…

Social Media Arrive in School; Principals Look at Impacts

Science.gov (United States)

Armistead, Lew

2010-01-01

Social media have the potential to improve educational opportunities for high school students, but also present legal and policy challenges for public school principals. Those were among opinions expressed in the 2010 Principals' Partnership Poll. The most frequently-cited request by the 306 respondents was help in integrating social media into…

Two correlated quasiparticles states in the principal series approximation

International Nuclear Information System (INIS)

Dukelsky, J.; Dussel, G.G.; Sofia, H.M.

1983-01-01

The principal series approximation is extended to the description of two correlated quasiparticles states, enabling a treatment of these states that takes into account the coupling among the two particle Green's function and the particle-hole one. This description is related to a random phase approximation treatment of collective states in open shell nuclei that includes simultaneously the particle-particle and particle-hole versions of the nuclear residual Hamiltonian. Using separable interactions it is found that the inclusion of the particle-particle part of the Hamiltonians greatly changes the properties of the 2 + states in the Sn isotopes

The Relationship Among Principal Preparation Programs, Professional Development, and Instructional Leadership Efficacy  

OpenAIRE

Thomas III, Harry R.

2015-01-01

This study presents a qualitative analysis of principals' perceptions of the relationship among principal preparation programs, professional development and instructional leadership confidence in one urban school division in Virginia. Levine (2005) argued that the principal has a salient effect on the instructional programs within schools, and the preparation and professional development of the principal affects the degree to which they maintain and improve instruction. To examine principal p...

Computing Cumulative Interest and Principal Paid For a Calendar Year

OpenAIRE

John O. MASON

2011-01-01

This paper demonstrates how easy it is use Microsoft Excel’s CUMPRINC and CUMIPMT functions to compute principal and interest paid for an entire year, even though the payments were made monthly. The CUMPRINC function computes the principal paid by a series of loan payments; the CUMIPMT function computes the interest paid. These two functions provide an alternative to preparing a monthly loan amortization schedule and adding up the amounts of monthly interest paid and principal paid for the ye...

Practices of Elementary Principals in Influencing New Teachers to Remain in Education

OpenAIRE

Palermo, Thelma D.

2002-01-01

The grounded theory presented in this study describes practices elementary principals utilize in influencing new teachers to remain in education. Eleven teachers and three elementary principals from one school division in Virginia participated in this study. Interview data were collected, elementary principals were shadowed, and documents were analyzed. Thematic categories and sub categories were formed through data analysis. The grounded theory that resulted from this study is: principals wh...

EphB1 as a Novel Drug Target to Combat Pain and Addiction

Science.gov (United States)

2016-09-01

Award Number: W81XWH-14-1-0220 Project Title: EphB1 as a Novel Drug Target to Combat Pain and Addiction Principal Investigator Name: Mark...Pain and Addiction 5a. CONTRACT NUMBER EphB1 as a Novel Drug Target to Combat Pain and Addiction 5b. GRANT NUMBER W81XWH-14-1-0220 5c. PROGRAM...SUBJECT TERMS Chronic neuropathic pain, opioid addiction , synaptic plasticity, EphB1 receptor, ephrin-B2, NMDA receptor, drug discovery 16. SECURITY

An Introductory Application of Principal Components to Cricket Data

Science.gov (United States)

Manage, Ananda B. W.; Scariano, Stephen M.

2013-01-01

Principal Component Analysis is widely used in applied multivariate data analysis, and this article shows how to motivate student interest in this topic using cricket sports data. Here, principal component analysis is successfully used to rank the cricket batsmen and bowlers who played in the 2012 Indian Premier League (IPL) competition. In…

Financial accountability: the principal or the school governing body ...

African Journals Online (AJOL)

The Schools Act 84 of 1996 prescribes how a school should manage its funds. It also provides guidelines for the school governing body and the principal on their roles and responsibilities in managing the finances of the school. However, there are school governing bodies and principals that have little knowledge of the ...

An analytics of electricity consumption characteristics based on principal component analysis

Science.gov (United States)

Feng, Junshu

2018-02-01

Abstract . More detailed analysis of the electricity consumption characteristics can make demand side management (DSM) much more targeted. In this paper, an analytics of electricity consumption characteristics based on principal component analysis (PCA) is given, which the PCA method can be used in to extract the main typical characteristics of electricity consumers. Then, electricity consumption characteristics matrix is designed, which can make a comparison of different typical electricity consumption characteristics between different types of consumers, such as industrial consumers, commercial consumers and residents. In our case study, the electricity consumption has been mainly divided into four characteristics: extreme peak using, peak using, peak-shifting using and others. Moreover, it has been found that industrial consumers shift their peak load often, meanwhile commercial and residential consumers have more peak-time consumption. The conclusions can provide decision support of DSM for the government and power providers.

Topography of the complete corticopontine projection: From experiments to principal maps

Directory of Open Access Journals (Sweden)

Trygve B Leergaard

2007-10-01

Full Text Available The mammalian brain is characterized by orderly spatial distribution of its cellular components, commonly referred to as topographical organization. The topography of cortical and subcortical maps is thought to represent functional or computational properties. In the present investigation, we have studied map transformations and organizing principles in the projections from the cerebral cortex to the pontine nuclei, with emphasis on the mapping of the cortex as a whole onto the pontine nuclei. Following single or multiple axonal tracer injections into different cortical regions, three-dimensional (3-D distributions of anterogradely labeled axons in the pontine nuclei were mapped. All 3-D reconstructed data sets were normalized to a standardized local coordinate system for the pontine nuclei and uploaded in a database application (FACCS, Functional Anatomy of the Cerebro-Cerebellar System, available via The Rodent Brain Workbench, http://www.rbwb.org. The database application allowed flexible use of the data in novel combinations, and use of a previously published data sets. Visualization of different combinations of data was used to explore alternative principles of organization. As a result of these analyses, a principal map of the topography of corticopontine projections was developed. This map followed the organization of early spatiotemporal gradients present in the cerebral cortex and the pontine nuclei. With the principal map for corticopontine projections, a fairly accurate prediction of pontine target area can be made for any site of origin in the cerebral cortex. The map and the underlying shared data sets represent a basis for modeling of topographical organization and structure-function relationships in this system.

A Theory of Tax Avoidance - Managerial Incentives for Tax Planning in a Multi-Task Principal-Agent Model

OpenAIRE

Ewert, Ralf; Niemann, Rainer

2014-01-01

We derive determinants of tax avoidance by means of a multi-task principal-agent model. We extend prevailing models by integrating both corporate and individual income taxation as well as by including tax planning effort in the agent’s action portfolio. Our model shows novel and apparently paradoxical results regarding the impact of increased tax rates on efforts, risks, and incentive schemes. First, the principal’s after-tax profit can increase with a higher corporate tax rate. Second, t...

Clinical target volume delineation including elective nodal irradiation in preoperative and definitive radiotherapy of pancreatic cancer

Directory of Open Access Journals (Sweden)

Caravatta Luciana

2012-06-01

Full Text Available Abstract Background Radiotherapy (RT is widely used in the treatment of pancreatic cancer. Currently, recommendation has been given for the delineation of the clinical target volume (CTV in adjuvant RT. Based on recently reviewed pathologic data, the aim of this study is to propose criteria for the CTV definition and delineation including elective nodal irradiation (ENI in the preoperative and definitive treatment of pancreatic cancer. Methods The anatomical structures of interest, as well as the abdominal vasculature were identified on intravenous contrast-enhanced CT scans of two different patients with pancreatic cancer of the head and the body. To delineate the lymph node area, a margin of 10 mm was added to the arteries. Results We proposed a set of guidelines for elective treatment of high-risk nodal areas and CTV delineation. Reference CT images were provided. Conclusions The proposed guidelines could be used for preoperative or definitive RT for carcinoma of the head and body of the pancreas. Further clinical investigations are needed to validate the defined CTVs.

Principal components analysis in clinical studies.

Science.gov (United States)

Zhang, Zhongheng; Castelló, Adela

2017-09-01

In multivariate analysis, independent variables are usually correlated to each other which can introduce multicollinearity in the regression models. One approach to solve this problem is to apply principal components analysis (PCA) over these variables. This method uses orthogonal transformation to represent sets of potentially correlated variables with principal components (PC) that are linearly uncorrelated. PCs are ordered so that the first PC has the largest possible variance and only some components are selected to represent the correlated variables. As a result, the dimension of the variable space is reduced. This tutorial illustrates how to perform PCA in R environment, the example is a simulated dataset in which two PCs are responsible for the majority of the variance in the data. Furthermore, the visualization of PCA is highlighted.

Becoming a Principal in Indonesia: Possibility, Pitfalls and Potential

Science.gov (United States)

Sumintono, Bambang; Sheyoputri, Elslee Y. A.; Jiang, Na; Misbach, Ifa H.; Jumintono

2015-01-01

The preparation and development of school leaders is now considered to be fundamental to school and system improvement. In the pursuit of educational change and reform, the leadership of the principal is deemed to be of critical importance. This qualitative study is part of a large scale research project that is exploring principal preparation and…

Principal Concerns: Iowa May Face Statewide Demand. Data Brief

Science.gov (United States)

DeArmond, Michael; Ouijdani, Monica

2012-01-01

When people talk about human capital or talent in public education, they generally focus on teachers, not principals. That's a mistake. School districts and states generally don't take a strategic approach toward managing their principal workforce. Often, they lack even the most basic information about who is leading their schools: Where do most…

The kinds of knowledge principals use: Implications for training

Directory of Open Access Journals (Sweden)

Angeliki Lazaridou

2009-01-01

Full Text Available Information about how school principals operate pertains mainly to the actions of principals. However, the kinds of knowledge that the principalship demands have not been isolated as clearly, more often than not being conflated with actions. As principals’ duties become more complex, it becomes more important to ground specific practices in robust knowledge of relevant theoretical principles. One aspect of the principal’s job where this is particularly germane is the resolution of unfamiliar, complex, unstructured challenges. This paper presents findings from research into how principals think when dealing with problematic situations, in particular the types of knowledge they use. Four broad categories of knowledge were identified and, within those, twelve specific types. The research lends credence to the oral report or think-aloud method for making thinking processes available for analysis, and the findings indicate how the content of preparation programs may be adjusted to better qualify principals for the contemporary demands of their work. A prime recommendation is the inclusion of opportunities for the development of tacit knowledge.

A Study of Perceived Leadership Styles as It Affects the Decision-Making Process Employed by Eleven Catholic School Principals in South Texas

Science.gov (United States)

Agbakoba, Mary Olivia

2017-01-01

Catholic School principals play an important role in the development of students' spiritual, social, and academic wellbeing. Consequently, in order to improve students' spiritual, social, and academic skill, it is vital to study the perceived leadership styles and decision-making of Catholic School Principals. Research questions include: "Is…

Optimal interface between principal deterrent systems and material accounting

International Nuclear Information System (INIS)

Deiermann, P.J.; Opelka, J.H.

1983-01-01

The purpose of this study is to find an optimal blend between three safeguards systems for special nuclear material (SNM), the material accounting system and the physical security and material control systems. The latter two are denoted as principal deterrent systems. The optimization methodology employed is a two-stage decision algorithm, first an explicit maximization of expected diverter benefits and subsequently a minimization of expected defender costs for changes in material accounting procedures and incremental improvements in the principal deterrent systems. The probability of diverter success function dependent upon the principal deterrents and material accounting system variables is developed. Within the range of certainty of the model, existing material accounting, material control and physical security practices are justified

Radiosurgical treatment planning for intracranial AVM based on images generated by principal component analysis. A simulation study

International Nuclear Information System (INIS)

Kawaguchi, Osamu; Kunieda, Etsuo; Nyui, Yoshiyuki

2009-01-01

One of the most important factors in stereotactic radiosurgery (SRS) for intracranial arteriovenous malformation (AVM) is to determine accurate target delineation of the nidus. However, since intracranial AVMs are complicated in structure, it is often difficult to clearly determine the target delineation. The purpose of this study was to investigate the usefulness of principal component analysis (PCA) on intra-arterial contrast enhanced dynamic CT (IADCT) images as a tool for delineating accurate target volumes for stereotactic radiosurgery of AVMs. IADCT and intravenous contrast-enhanced CT (IVCT) were used to examine 4 randomly selected cases of AVM. PCA images were generated from the IADCT data. The first component images were considered feeding artery predominant, the second component images were considered draining vein predominant, and the third component images were considered background. Target delineations were first carried out from IVCT, and then again while referring to the first and second components of the PCA images. Dose calculation simulations for radiosurgical treatment plans with IVCT and PCA images were performed. Dose volume histograms of the vein areas as well as the target volumes were compared. In all cases, the calculated target volumes based on IVCT images were larger than those based on PCA images, and the irradiation doses for the vein areas were reduced. In this study, we simulated radiosurgical treatment planning for intracranial AVM based on PCA images. By using PCA images, the irradiation doses for the vein areas were substantially reduced. (author)

Water reuse systems: A review of the principal components

Science.gov (United States)

Lucchetti, G.; Gray, G.A.

1988-01-01

Principal components of water reuse systems include ammonia removal, disease control, temperature control, aeration, and particulate filtration. Effective ammonia removal techniques include air stripping, ion exchange, and biofiltration. Selection of a particular technique largely depends on site-specific requirements (e.g., space, existing water quality, and fish densities). Disease control, although often overlooked, is a major problem in reuse systems. Pathogens can be controlled most effectively with ultraviolet radiation, ozone, or chlorine. Simple and inexpensive methods are available to increase oxygen concentration and eliminate gas supersaturation, these include commercial aerators, air injectors, and packed columns. Temperature control is a major advantage of reuse systems, but the equipment required can be expensive, particularly if water temperature must be rigidly controlled and ambient air temperature fluctuates. Filtration can be readily accomplished with a hydrocyclone or sand filter that increases overall system efficiency. Based on criteria of adaptability, efficiency, and reasonable cost, we recommend components for a small water reuse system.

The school food environment and adolescent obesity: qualitative insights from high school principals and food service personnel

Directory of Open Access Journals (Sweden)

Ellerbeck Edward F

2007-05-01

Full Text Available Abstract Objectives To examine high school personnel's perceptions of the school environment, its impact on obesity, and the potential impact of legislation regulating schools' food/beverage offerings. Methods Semi-structured interviews were conducted with the principal (n = 8 and dietitian/food service manager (n = 7 at 8 schools (4 rural, 4 suburban participating in a larger study examining the relationship between the school environment and adolescent health behavior patterns. Results Principal themes included: 1 Obesity is a problem in general, but not at their school, 2 Schools have been unfairly targeted above more salient factors (e.g., community and home environment, 3 Attempts at change should start before high school, 4 Student health is one priority area among multiple competing demands; academic achievement is the top priority, 5 Legislation should be informed by educators and better incorporate the school's perspective. Food service themes included: 1 Obesity is not a problem at their school; school food service is not the cause, 2 Food offerings are based largely on the importance of preparing students for the real world by providing choice and the need to maintain high participation rates; both healthy and unhealthy options are available, 3 A la carte keeps lunch participation high and prices low but should be used as a supplement, not a replacement, to the main meal, 4 Vending provides school's additional revenue; vending is not part of food service and is appropriate if it does not interfere with the lunch program. Conclusion Discrepancies exist between government/public health officials and school personnel that may inhibit collaborative efforts to address obesity through modifications to the school environment. Future policy initiatives may be enhanced by seeking the input of school personnel, providing recommendations firmly grounded in evidence-based practice, framing initiatives in terms of their potential impact on the

Wavelet decomposition based principal component analysis for face recognition using MATLAB

Science.gov (United States)

Sharma, Mahesh Kumar; Sharma, Shashikant; Leeprechanon, Nopbhorn; Ranjan, Aashish

2016-03-01

For the realization of face recognition systems in the static as well as in the real time frame, algorithms such as principal component analysis, independent component analysis, linear discriminate analysis, neural networks and genetic algorithms are used for decades. This paper discusses an approach which is a wavelet decomposition based principal component analysis for face recognition. Principal component analysis is chosen over other algorithms due to its relative simplicity, efficiency, and robustness features. The term face recognition stands for identifying a person from his facial gestures and having resemblance with factor analysis in some sense, i.e. extraction of the principal component of an image. Principal component analysis is subjected to some drawbacks, mainly the poor discriminatory power and the large computational load in finding eigenvectors, in particular. These drawbacks can be greatly reduced by combining both wavelet transform decomposition for feature extraction and principal component analysis for pattern representation and classification together, by analyzing the facial gestures into space and time domain, where, frequency and time are used interchangeably. From the experimental results, it is envisaged that this face recognition method has made a significant percentage improvement in recognition rate as well as having a better computational efficiency.

High School Principals and the High School Journalism Program.

Science.gov (United States)

Peterson, Jane W.

A study asked selected high school principals to respond to statements about the value of high school journalism to the high school student and about the rights and responsibilities of the high school journalist. These responses were then checked against such information as whether or not the high school principal had worked on a high school…

On the principal state method for runlength limited sequences

NARCIS (Netherlands)

Tjalkens, T.J.

1994-01-01

Presents a detailed result on Franaszek's (1968) principal state method for the generation of run-length constrained codes. The authors show that, whenever the constraints k and d satisfy k 2d>0, the set of "principal states" is s0, s1, ···, sk-1. Thus there is no need for Franaszek's search

Using Concept Mapping to Build Concept the Competence of School Principals

Directory of Open Access Journals (Sweden)

Mustamin Mustamin

2012-08-01

Full Text Available More and more the competence concept of school principals have an impact on two conditions, namely: (1 to develop the concept can complement and support each other; and (2 to develop the concept of possible contradict, giving rise to different interpretations. Therefore, this becomes the main issue researchers to identify the competence concept of school principals with adaptation of Jackson-Trochim method that is capable of illustrating the concept of competencies. Results of adaptation Jackson-Trochim method that school principals should have three types of competencies to lead the school effectively and efficiently. Kind of competencies are such as school leadership, instructional leadership, and operational leadership. Based on these results, the adaptationof Jackson-Trochim method to build the competence concept of school principals suggests this concept obtained may serve as a reference for school principals continue to build competencies in the future

Subjective Performance Evaluations, Self-esteem, and Ego-threats in Principal-agent Relations

DEFF Research Database (Denmark)

Sebald, Alexander Christopher; Walzl, Markus

find that agents sanction whenever the feedback of principals is below their subjective self-evaluations even if the agents' payoff is independent of the principals' feedback. Based on our experimental analysis we propose a principal-agent model with subjective performance evaluations that accommodates...

Dimensionality reduction of collective motion by principal manifolds

Science.gov (United States)

Gajamannage, Kelum; Butail, Sachit; Porfiri, Maurizio; Bollt, Erik M.

2015-01-01

While the existence of low-dimensional embedding manifolds has been shown in patterns of collective motion, the current battery of nonlinear dimensionality reduction methods is not amenable to the analysis of such manifolds. This is mainly due to the necessary spectral decomposition step, which limits control over the mapping from the original high-dimensional space to the embedding space. Here, we propose an alternative approach that demands a two-dimensional embedding which topologically summarizes the high-dimensional data. In this sense, our approach is closely related to the construction of one-dimensional principal curves that minimize orthogonal error to data points subject to smoothness constraints. Specifically, we construct a two-dimensional principal manifold directly in the high-dimensional space using cubic smoothing splines, and define the embedding coordinates in terms of geodesic distances. Thus, the mapping from the high-dimensional data to the manifold is defined in terms of local coordinates. Through representative examples, we show that compared to existing nonlinear dimensionality reduction methods, the principal manifold retains the original structure even in noisy and sparse datasets. The principal manifold finding algorithm is applied to configurations obtained from a dynamical system of multiple agents simulating a complex maneuver called predator mobbing, and the resulting two-dimensional embedding is compared with that of a well-established nonlinear dimensionality reduction method.

The Networked Principal: Examining Principals' Social Relationships and Transformational Leadership in School and District Networks

Science.gov (United States)

Moolenaar, Nienke M.; Sleegers, Peter J. C.

2015-01-01

Purpose: While in everyday practice, school leaders are often involved in social relationships with a variety of stakeholders both within and outside their own schools, studies on school leaders' networks often focus either on networks within or outside schools. The purpose of this paper is to investigate the extent to which principals occupy…

Target support for inertial confinement fusion

International Nuclear Information System (INIS)

Schultz, K.R.

1995-08-01

General Atomics (GA) plays an important industrial support role for the US Inertial Confinement Fusion (ICF) program in the area of target technology. This includes three major activities: target fabrication support, target handling systems development, and target chamber design. The work includes target fabrication for existing ICF experiments, target and target system development for future experiments, and target research and target chamber design for experiments on future machines, such as the National Ignition Facility (NIF)

Geometry of Quantum Principal Bundles. Pt. 1

International Nuclear Information System (INIS)

Durdevic, M.

1996-01-01

A theory of principal bundles possessing quantum structure groups and classical base manifolds is presented. Structural analysis of such quantum principal bundles is performed. A differential calculus is constructed, combining differential forms on the base manifold with an appropriate differential calculus on the structure quantum group. Relations between the calculus on the group and the calculus on the bundle are investigated. A concept of (pseudo)tensoriality is formulated. The formalism of connections is developed. In particular, operators of horizontal projection, covariant derivative and curvature are constructed and analyzed. Generalizations of the first Structure Equation and of the Bianchi identity are found. Illustrative examples are presented. (orig.)

Emotionally Intelligent Leadership: An Analysis of Targeted Interventions for Aspiring School Leaders in Texas

Science.gov (United States)

Kearney, W. Sean; Kelsey, Cheryl; Sinkfield, Carolin

2014-01-01

This study measures the impact of targeted interventions on the emotional intelligence of aspiring principals. The interventions utilized were designed by Nelson and Low (2011) to increase emotionally intelligent leadership skills in the following six areas: social awareness/active listening; anxiety management; decision making; appropriate use of…

Genomes2Drugs: identifies target proteins and lead drugs from proteome data.

LENUS (Irish Health Repository)

Toomey, David

2009-01-01

BACKGROUND: Genome sequencing and bioinformatics have provided the full hypothetical proteome of many pathogenic organisms. Advances in microarray and mass spectrometry have also yielded large output datasets of possible target proteins\\/genes. However, the challenge remains to identify new targets for drug discovery from this wealth of information. Further analysis includes bioinformatics and\\/or molecular biology tools to validate the findings. This is time consuming and expensive, and could fail to yield novel drugs if protein purification and crystallography is impossible. To pre-empt this, a researcher may want to rapidly filter the output datasets for proteins that show good homology to proteins that have already been structurally characterised or proteins that are already targets for known drugs. Critically, those researchers developing novel antibiotics need to select out the proteins that show close homology to any human proteins, as future inhibitors are likely to cross-react with the host protein, causing off-target toxicity effects later in clinical trials. METHODOLOGY\\/PRINCIPAL FINDINGS: To solve many of these issues, we have developed a free online resource called Genomes2Drugs which ranks sequences to identify proteins that are (i) homologous to previously crystallized proteins or (ii) targets of known drugs, but are (iii) not homologous to human proteins. When tested using the Plasmodium falciparum malarial genome the program correctly enriched the ranked list of proteins with known drug target proteins. CONCLUSIONS\\/SIGNIFICANCE: Genomes2Drugs rapidly identifies proteins that are likely to succeed in drug discovery pipelines. This free online resource helps in the identification of potential drug targets. Importantly, the program further highlights proteins that are likely to be inhibited by FDA-approved drugs. These drugs can then be rapidly moved into Phase IV clinical studies under \\'change-of-application\\' patents.

Genomes2Drugs: identifies target proteins and lead drugs from proteome data.

Directory of Open Access Journals (Sweden)

David Toomey

Full Text Available BACKGROUND: Genome sequencing and bioinformatics have provided the full hypothetical proteome of many pathogenic organisms. Advances in microarray and mass spectrometry have also yielded large output datasets of possible target proteins/genes. However, the challenge remains to identify new targets for drug discovery from this wealth of information. Further analysis includes bioinformatics and/or molecular biology tools to validate the findings. This is time consuming and expensive, and could fail to yield novel drugs if protein purification and crystallography is impossible. To pre-empt this, a researcher may want to rapidly filter the output datasets for proteins that show good homology to proteins that have already been structurally characterised or proteins that are already targets for known drugs. Critically, those researchers developing novel antibiotics need to select out the proteins that show close homology to any human proteins, as future inhibitors are likely to cross-react with the host protein, causing off-target toxicity effects later in clinical trials. METHODOLOGY/PRINCIPAL FINDINGS: To solve many of these issues, we have developed a free online resource called Genomes2Drugs which ranks sequences to identify proteins that are (i homologous to previously crystallized proteins or (ii targets of known drugs, but are (iii not homologous to human proteins. When tested using the Plasmodium falciparum malarial genome the program correctly enriched the ranked list of proteins with known drug target proteins. CONCLUSIONS/SIGNIFICANCE: Genomes2Drugs rapidly identifies proteins that are likely to succeed in drug discovery pipelines. This free online resource helps in the identification of potential drug targets. Importantly, the program further highlights proteins that are likely to be inhibited by FDA-approved drugs. These drugs can then be rapidly moved into Phase IV clinical studies under 'change-of-application' patents.

Principals' Self-Efficacy: Relations with Job Autonomy, Job Satisfaction, and Contextual Constraints

Science.gov (United States)

Federici, Roger A.

2013-01-01

The purpose of the present study was to explore relations between principals' self-efficacy, perceived job autonomy, job satisfaction, and perceived contextual constraints to autonomy. Principal self-efficacy was measured by a multidimensional scale called the Norwegian Principal Self-Efficacy Scale. Job autonomy, job satisfaction, and contextual…

77 FR 62185 - Temporary Rule Regarding Principal Trades With Certain Advisory Clients

Science.gov (United States)

2012-10-12

... 3235-AJ96 Temporary Rule Regarding Principal Trades With Certain Advisory Clients AGENCY: Securities... principal capacity in transactions with certain of their advisory clients. The amendment would extend the... Advisers Act when they act in a principal capacity in transactions with certain of their advisory clients...

75 FR 75650 - Temporary Rule Regarding Principal Trades With Certain Advisory Clients

Science.gov (United States)

2010-12-06

... 3235-AJ96 Temporary Rule Regarding Principal Trades With Certain Advisory Clients AGENCY: Securities... principal capacity in transactions with certain of their advisory clients. The amendment would extend the... Advisers Act when they act in a principal capacity in transactions with certain of their advisory clients...

Constructing principals' professional identities through life stories: an exploration

Directory of Open Access Journals (Sweden)

Jabulani Mpungose

2010-01-01

Full Text Available Adopting a humanistic perspective to the study of leadership, I discuss and describe how school principals adapt to their new roles, owing to the new education policies and educational restructuring within the South African Department of Education. The Life History approach was used to collect data from six selected school principals in KwaZulu-Natal. On the basis of the analysis of data, I conclude that leaders create their provisional selves and construct their professional identities from their personal and professional knowledge. Provisional selves, in this context, are temporary solutions principals use to close the gap between their current capacities and self-concepts, and the ideas they hold about what attitudes and behaviours are expected in their new roles.

Leadership Styles of Principals and Job Performance of Staff in ...

African Journals Online (AJOL)

Leadership Styles of Principals and Job Performance of Staff in Secondary Schools in Delta State of Nigeria. ... recommended that principals should adopt the democratic leadership style to boost better job performance among staff and in essence enhance administrative effectiveness and students‟ academic performance.

How Does a Community of Principals Develop Leadership for Technology-Enhanced Science?

Science.gov (United States)

Gerard, Libby F.; Bowyer, Jane B.; Linn, Marcia C.

2010-01-01

Active principal leadership can help sustain and scale science curriculum reform. This study illustrates how principal leadership developed in a professional learning community to support a technology-enhanced science curriculum reform funded by the National Science Foundation. Seven middle school and high school principals in one urban-fringe…

The Gender of Secondary School Principals.

Science.gov (United States)

Bonuso, Carl; Shakeshaft, Charol

1983-01-01

A study was conducted to understand why so few of the secondary school principals in New York State are women. Results suggest two possible causes: either sufficient women candidates do not apply for the positions, or sex discrimination still exists. (KH)

Principal component structure and sport-specific differences in the running one-leg vertical jump.

Science.gov (United States)

Laffaye, G; Bardy, B G; Durey, A

2007-05-01

The aim of this study is to identify the kinetic principal components involved in one-leg running vertical jumps, as well as the potential differences between specialists from different sports. The sample was composed of 25 regional skilled athletes who play different jumping sports (volleyball players, handball players, basketball players, high jumpers and novices), who performed a running one-leg jump. A principal component analysis was performed on the data obtained from the 200 tested jumps in order to identify the principal components summarizing the six variables extracted from the force-time curve. Two principal components including six variables accounted for 78 % of the variance in jump height. Running one-leg vertical jump performance was predicted by a temporal component (that brings together impulse time, eccentric time and vertical displacement of the center of mass) and a force component (who brings together relative peak of force and power, and rate of force development). A comparison made among athletes revealed a temporal-prevailing profile for volleyball players, and a force-dominant profile for Fosbury high jumpers. Novices showed an ineffective utilization of the force component, while handball and basketball players showed heterogeneous and neutral component profiles. Participants will use a jumping strategy in which variables related to either the magnitude or timing of force production will be closely coupled; athletes from different sporting backgrounds will use a jumping strategy that reflects the inherent demands of their chosen sport.

Principal Leadership and Teacher Motivation under High-Stakes Accountability Policies

Science.gov (United States)

Finnigan, Kara S.

2010-01-01

This article examines principal leadership and teacher motivation in schools under accountability sanctions. The conceptual framework is grounded in research on expectancy theory and transformational leadership. The study involves a survey of Chicago teachers and indicates that principal instructional leadership and support for change are…

Principals' Opinions of Organisational Justice in Elementary Schools in Turkey

Science.gov (United States)

Aydin, Inayet; Karaman-Kepenekci, Yasemin

2008-01-01

Purpose--This study aims to present the opinions of public elementary school principals in Turkey about the current organisational justice practices among teachers from the distributive, procedural, interactional, and rectificatory dimensions. Design/methodology/approach--The opinions of 11 public elementary school principals in Ankara about…

Principals' Perceptions of Public Schools' Professional Development Changes during NCLB

Science.gov (United States)

Wieczorek, Douglas

2017-01-01

This study investigated public school principals' reports of professional development implementation at the school level while working in different state- and local-level contexts (state accountability level, geographic locations, socioeconomic status, demographics, and grade levels). I attempted to measure principals' reported changes in levels…

Generalized principal resonance in oscillatory systems of second order; Resonancia principal generalizada en sistemas oscilatorios de segundo orden

Energy Technology Data Exchange (ETDEWEB)

Munoz Aguirre, E. [Universidad Autonoma de Puebla, Oaxaca (Mexico); Alexandrov, V. V. [Benemerita Universidad Autonoma de Puebla, Puebla (Mexico)

2001-02-01

This paper will describe the generalized principal resonance of systems as described by the second order of ordinary differential equations and proved by the Pontriaguin maximal principle to coincide with the lengthened solution of an external problem of the same system. The results are verified in special cases of general resonance and parametric resonance for the Mathieu equation. [Spanish] En el presente articulo se estudia la resonancia principal generalizada para sistemas descritos por ecuaciones diferenciales ordinarias de segundo orden y se demuestra con ayuda del principio del maximo de Pontriaguin, la coincidencia de esta con la solucion prolongada de un problema extremal para el mismo sistema. Ademas se verifican estos resultados en los casos particulares de resonancia general y resonancia parametrica para la ecuacion de Mathieu.

Endogenous retinoic acid activity in principal cells and intercalated cells of mouse collecting duct system.

Directory of Open Access Journals (Sweden)

Yuen Fei Wong

2011-02-01

Full Text Available Retinoic acid is the bioactive derivative of vitamin A, which plays an indispensible role in kidney development by activating retinoic acid receptors. Although the location, concentration and roles of endogenous retinoic acid in post-natal kidneys are poorly defined, there is accumulating evidence linking post-natal vitamin A deficiency to impaired renal concentrating and acidifying capacity associated with increased susceptibility to urolithiasis, renal inflammation and scarring. The aim of this study is to examine the presence and the detailed localization of endogenous retinoic acid activity in neonatal, young and adult mouse kidneys, to establish a fundamental ground for further research into potential target genes, as well as physiological and pathophysiological roles of endogenous retinoic acid in the post-natal kidneys.RARE-hsp68-lacZ transgenic mice were employed as a reporter for endogenous retinoic acid activity that was determined by X-gal assay and immunostaining of the reporter gene product, β-galactosidase. Double immunostaining was performed for β-galactosidase and markers of kidney tubules to localize retinoic acid activity. Distinct pattern of retinoic acid activity was observed in kidneys, which is higher in neonatal and 1- to 3-week-old mice than that in 5- and 8-week-old mice. The activity was present specifically in the principal cells and the intercalated cells of the collecting duct system in all age groups, but was absent from the glomeruli, proximal tubules, thin limbs of Henle's loop and distal tubules.Endogenous retinoic acid activity exists in principal cells and intercalated cells of the mouse collecting duct system after birth and persists into adulthood. This observation provides novel insights into potential roles for endogenous retinoic acid beyond nephrogenesis and warrants further studies to investigate target genes and functions of endogenous retinoic acid in the kidney after birth, particularly in the

A Matter of Definition: Is There Truly a Shortage of School Principals?

Science.gov (United States)

Roza, Marguerite

Although some districts and areas have experienced difficulty finding good principals, there are far more candidates certified to be principals than there are principal vacancies to fill. This report describes a study based on a written indepth survey of human-resource directors supplemented by formal survey questions to school superintendents and…

A Principal Striving for Effective Instructional Leadership in an Era of Accountability

Science.gov (United States)

Mazzoni, Matthew J.

2017-01-01

The purpose of this case study was to explore a principal's experiences and how they aligned to Hallinger and Murphy's (1985) effective instructional leadership practices in an era of accountability. This study of effective principal leadership is timely and relevant due to the recent implementation of national and state mandates for principals to…

Statistical intercomparison of global climate models: A common principal component approach with application to GCM data

International Nuclear Information System (INIS)

Sengupta, S.K.; Boyle, J.S.

1993-05-01

Variables describing atmospheric circulation and other climate parameters derived from various GCMs and obtained from observations can be represented on a spatio-temporal grid (lattice) structure. The primary objective of this paper is to explore existing as well as some new statistical methods to analyze such data structures for the purpose of model diagnostics and intercomparison from a statistical perspective. Among the several statistical methods considered here, a new method based on common principal components appears most promising for the purpose of intercomparison of spatio-temporal data structures arising in the task of model/model and model/data intercomparison. A complete strategy for such an intercomparison is outlined. The strategy includes two steps. First, the commonality of spatial structures in two (or more) fields is captured in the common principal vectors. Second, the corresponding principal components obtained as time series are then compared on the basis of similarities in their temporal evolution

Discretion in Student Discipline: Insight into Elementary Principals' Decision Making

Science.gov (United States)

Findlay, Nora M.

2015-01-01

Little research exists that examines the exercise of discretion by principals in their disciplinary decision making. This study sought to understand the application of values by principals as they engage in student disciplinary decision making within legally fixed parameters of their administrative discretion. This qualitative methodology used…

Religious Intolerance: The Case of Principals in Multi-faith Schools ...

African Journals Online (AJOL)

This article reports on a qualitative study framed in a phenomenological research design and aimed at investigating how school principals describe their mediating role when implementing religion-in-education policy at schools. Data were collected by means of narrative interviews. Stories of twelve school principals ...

Effective Principals, Effective Schools: Arriving at Site-Based Decision-Making with Successful Principals and Teacher Participation.

Science.gov (United States)

Charles, Gregory Stewart; Karr-Kidwell, PJ

This paper reviews research on principals' and teachers' roles in site-based decision making (SBDM). Research examining teacher participation in SBDM is reviewed, finding that higher quality teaching behaviors and higher student academic attainment resulted from teacher participation. The review focuses on steps in implementing SBDM, means for…

Creating a New Approach to Principal Leadership: The National Institute of School Leadership has Borrowed from the Leadership Practices of Other Professions to Build an Innovative Program for Principals

Science.gov (United States)

Hughes, Robert C.

2005-01-01

The author describes a principal training program resulting from a study that found disconnects between education leadership programs and what principals need to know and be able to do to guide improved instruction. The National Institute for School Leadership program focuses on practicing principals but also has applications for aspiring…

Sparse Principal Component Analysis in Medical Shape Modeling

DEFF Research Database (Denmark)

Sjöstrand, Karl; Stegmann, Mikkel Bille; Larsen, Rasmus

2006-01-01

Principal component analysis (PCA) is a widely used tool in medical image analysis for data reduction, model building, and data understanding and exploration. While PCA is a holistic approach where each new variable is a linear combination of all original variables, sparse PCA (SPCA) aims...... analysis in medicine. Results for three different data sets are given in relation to standard PCA and sparse PCA by simple thresholding of sufficiently small loadings. Focus is on a recent algorithm for computing sparse principal components, but a review of other approaches is supplied as well. The SPCA...

Opinions of Primary and Secondary School Principals about Internal and External Motivation

Science.gov (United States)

Erdem, Ali Riza; Cicekdemir, Ibrahim

2016-01-01

Problem Statement: "Motivation" can be defined as the action of directing human behavior in a desirable way. School principals are not only the managers who are the most responsible for the school. The vice principals who are officially charged and help the principals with the school tasks are also called school managers. School managers…

Preparing Novice Principals in Australia and Turkey: How Similar Are Their Needs?

Science.gov (United States)

Wildy, Helen; Clarke, Simon; Styles, Irene; Beycioglu, Kadir

2010-01-01

Part of a 13-nation, cross-cultural study of the extent to which principals perceive their pre-appointment experiences had prepared them for the job, the International Study of Principal Preparation (ISPP), this paper compares the responses of novice principals in Turkey and Western Australia. Using a survey based on data from case studies of…

Impact of Angiotensin Type 1A Receptors in Principal Cells of the Collecting Duct on Blood Pressure and Hypertension.

Science.gov (United States)

Chen, Daian; Stegbauer, Johannes; Sparks, Matthew A; Kohan, Donald; Griffiths, Robert; Herrera, Marcela; Gurley, Susan B; Coffman, Thomas M

2016-06-01

The main actions of the renin-angiotensin system to control blood pressure (BP) are mediated by the angiotensin type 1 receptors (AT1Rs). The major murine AT1R isoform, AT1AR, is expressed throughout the nephron, including the collecting duct in both principal and intercalated cells. Principal cells play the major role in sodium and water reabsorption. Although aldosterone is considered to be the dominant regulator of sodium reabsorption by principal cells, recent studies suggest a role for direct actions of AT1R. To specifically examine the contributions of AT1AR in principal cells to BP regulation and the development of hypertension in vivo, we generated inbred 129/SvEv mice with deletion of AT1AR from principal cells (PCKO). At baseline, we found that BPs measured by radiotelemetry were similar between PCKOs and controls. During 1-week of low-salt diet (hypertension, there was a modest but significant attenuation of hypertension in PCKOs (163±6 mm Hg) compared with controls (178±2 mm Hg; Phypertension and epithelial sodium channel activation. © 2016 American Heart Association, Inc.

Therapeutic Targeting of Lipid Droplets as Disease Markers in Ovarian Cancer

Science.gov (United States)

2016-03-01

Defective Autophagy and Increased Lipid Droplet Biogenesis in vitro and in vivo in Ovarian Cancer. American Association of Cancer Research , May 18-22...AWARD NUMBER: W81XWH-13-1-0119 TITLE: Therapeutic Targeting of Lipid Droplets as Disease Markers in Ovarian Cancer PRINCIPAL INVESTIGATOR...FOR: U.S. Army Medical Research and Materiel Command Fort Detrick, Maryland 21702-5012 DISTRIBUTION STATEMENT: Approved for Public Release

Audiovisual synchrony enhances BOLD responses in a brain network including multisensory STS while also enhancing target-detection performance for both modalities

Science.gov (United States)

Marchant, Jennifer L; Ruff, Christian C; Driver, Jon

2012-01-01

The brain seeks to combine related inputs from different senses (e.g., hearing and vision), via multisensory integration. Temporal information can indicate whether stimuli in different senses are related or not. A recent human fMRI study (Noesselt et al. [2007]: J Neurosci 27:11431–11441) used auditory and visual trains of beeps and flashes with erratic timing, manipulating whether auditory and visual trains were synchronous or unrelated in temporal pattern. A region of superior temporal sulcus (STS) showed higher BOLD signal for the synchronous condition. But this could not be related to performance, and it remained unclear if the erratic, unpredictable nature of the stimulus trains was important. Here we compared synchronous audiovisual trains to asynchronous trains, while using a behavioral task requiring detection of higher-intensity target events in either modality. We further varied whether the stimulus trains had predictable temporal pattern or not. Synchrony (versus lag) between auditory and visual trains enhanced behavioral sensitivity (d') to intensity targets in either modality, regardless of predictable versus unpredictable patterning. The analogous contrast in fMRI revealed BOLD increases in several brain areas, including the left STS region reported by Noesselt et al. [2007: J Neurosci 27:11431–11441]. The synchrony effect on BOLD here correlated with the subject-by-subject impact on performance. Predictability of temporal pattern did not affect target detection performance or STS activity, but did lead to an interaction with audiovisual synchrony for BOLD in inferior parietal cortex. PMID:21953980

From Redistribution to Recognition: How School Principals Perceive Social Justice

Science.gov (United States)

Wang, Fei

2016-01-01

Where there are people, there is social in/justice. Using Nancy Fraser's framework, this qualitative research examines how school principals perceive social justice in schools. Twenty-one elementary and secondary school principals were interviewed in the Greater Toronto Area. The study provides some empirical evidence on the ways social…

The Relationship of Principal Conflict Management Style and School Climate

Science.gov (United States)

Boucher, Miriam Miley

2013-01-01

Using a mixed-methods design, this study examined conflict management styles of elementary school principals in South Carolina and the relationship of conflict management style and school climate. The Rahim Organizational Conflict Inventory-II, Form B, which identifies five styles of managing conflict, was used to determine principal conflict…

High School Principals as Leaders: Styles and Sources of Power

Science.gov (United States)

Brinia, Vasiliki; Papantoniou, Eva

2016-01-01

Purpose: The purpose of this paper is to present the characteristics of leadership (style adopted, sources of power exercised and factors affecting leadership) of high school principals in Greece. Design/Methodology/Approach: In total, 235 school principals were surveyed using questionnaires. These questionnaires assessed how often they adopted…

Evading Equity: Principal Autonomy under the Bloomberg-Klein Market Regime

Science.gov (United States)

Lewis-Durham, Tiffanie C.

2015-01-01

Using New York City schools as a case study, this study draws on interview data from principals, district consultants and administrators, and principal's union representatives to explore the relationship between market-based reform and colorblindness in educational policy. The study is informed by colorblindness theory, which explores the subtle…

School Principals' Authentic Leadership and Teachers' Psychological Capital: Teachers' Perspectives

Science.gov (United States)

Feng, Feng-I

2016-01-01

This study examined teachers' perceptions of principals' authentic leadership and the relationship of authentic leadership to teachers' psychological capital in Taiwan. A total of 1,429 elementary and secondary school teachers were surveyed. The results showed that teachers perceived their principals' authentic leadership as moderate and that the…

Barriers to Implementing the Response to Intervention Framework in Secondary Schools: Interviews with Secondary Principals

Science.gov (United States)

Bartholomew, Mitch; De Jong, David

2017-01-01

Despite the successful implementation of the Response to Intervention (RtI) framework in many elementary schools, there is little evidence of successful implementation in high school settings. Several themes emerged from the interviews of nine secondary principals, including a lack of knowledge and training for successful implementation, the…

Diagnosis of multidetector spiral CT and its reconstruction techniques in trachea and principal bronchus tumors

Energy Technology Data Exchange (ETDEWEB)

Mingyue, Luo; Hong, Shan; Zaibo, Jiang; Lufang, Li; Jiansheng, Zhang [Zhongshan Univ., Guangzhou (China). The Third Univ. Hospital, Dept. of Radiology; Lijia, Gu; Shaohong, Huang; Yi, Jin; Zhiqiang, Hou

2003-12-01

Objective: To investigate the clinical diagnostic value of multidetector spiral CT (MSCT) and its reconstruction techniques including multiplanar volume reformation (MPVR), volume rendering (VR), and virtual bronchoscopy (VB) in the trachea and principal bronchus tumors. Methods: Thin slice MSCT scanning was performed in 31 patients with suspected trachea or principal bronchus tumors, and image reconstruction data were formed after retro-reconstructing of initial scanning data. MPVR, VR, and VB images were obtained respectively by postprocessing of image reconstruction data with MPVR, VR, and VB image processing software in AW workstation. The findings of MSCT initial axial images, MPVR, VR, and VB images were compared with surgical and pathological results. Results: MSCT initial axial images combined with MPVR, VR, and VB images displayed the locations (tracheae, n=19; right principal bronchi, n=6; left principal bronchi, n=6), morphologies (endoluminal nodular tumors with narrow bases, n=2; endoluminal nodular tumors with wide bases, n=13; intraluminal and extraluminal massive tumors, n=16), internal features (1 had homogeneous density, 1 had low density, they both without obvious enhancement; 23 squamous cell carcinomas and 3 adenocarcinomas had fairly homogeneous density and rather obvious enhancement; 1 had homogeneous density, 1 had inhomogeneous density, 1 had punctate calcification, all with obvious enhancement), extramural invasion situations (broke through only serous membrane, n=1; no clear border with right atelectatic lung tissue, n=1; ranges of extramural invasion 4-56 mm, n=14), morphologies of luminal stenoses (eccentric, n=1; irregular, n=26; circular, n=3; conical interruption, n=1), extents (mild, n=5; moderate, n=7; severe, n=19); measured longitudinal invasion ranges (only 3 mm, n=1; invaded the whole right principal bronchus wall and carina, n=1; 5-68 mm, n=29), and distances between principal bronchus tumors and carina (invaded carina, n=1

Instructional Leadership Behaviors in Principals Who Attended an Assistant Principals' Academy: Self-Reports and Teacher Perceptions

Science.gov (United States)

Gurley, D. Keith; Anast-May, Linda; O'Neal, Marcia; Lee, H. T.; Shores, Melanie

2015-01-01

Focus on the development of instructional leadership skills for school principals in the U.S. continues to be at the forefront of educational research and reform in response to the increased call for accountability. In this article we review relevant literature regarding instructional leadership from a historical perspective, then present a…

Perceptions of School Principals on Participation in Professional Learning Communities as Job-Embedded Learning

Science.gov (United States)

Gaudioso, Jennifer A.

2017-01-01

Perceptions of School Principals on Participation in Professional Learning Communities as Job-Embedded Learning Jennifer Gaudioso Principal Professional Learning Communities (PPLCs) have emerged as a vehicle for professional development of principals, but there is little research on how principals experience PPLCs or how districts can support…

Interpretable functional principal component analysis.

Science.gov (United States)

Lin, Zhenhua; Wang, Liangliang; Cao, Jiguo

2016-09-01

Functional principal component analysis (FPCA) is a popular approach to explore major sources of variation in a sample of random curves. These major sources of variation are represented by functional principal components (FPCs). The intervals where the values of FPCs are significant are interpreted as where sample curves have major variations. However, these intervals are often hard for naïve users to identify, because of the vague definition of "significant values". In this article, we develop a novel penalty-based method to derive FPCs that are only nonzero precisely in the intervals where the values of FPCs are significant, whence the derived FPCs possess better interpretability than the FPCs derived from existing methods. To compute the proposed FPCs, we devise an efficient algorithm based on projection deflation techniques. We show that the proposed interpretable FPCs are strongly consistent and asymptotically normal under mild conditions. Simulation studies confirm that with a competitive performance in explaining variations of sample curves, the proposed FPCs are more interpretable than the traditional counterparts. This advantage is demonstrated by analyzing two real datasets, namely, electroencephalography data and Canadian weather data. © 2015, The International Biometric Society.

Principal Components as a Data Reduction and Noise Reduction Technique

Science.gov (United States)

Imhoff, M. L.; Campbell, W. J.

1982-01-01

The potential of principal components as a pipeline data reduction technique for thematic mapper data was assessed and principal components analysis and its transformation as a noise reduction technique was examined. Two primary factors were considered: (1) how might data reduction and noise reduction using the principal components transformation affect the extraction of accurate spectral classifications; and (2) what are the real savings in terms of computer processing and storage costs of using reduced data over the full 7-band TM complement. An area in central Pennsylvania was chosen for a study area. The image data for the project were collected using the Earth Resources Laboratory's thematic mapper simulator (TMS) instrument.

Setting the Direction: The Role of the Principal in Developing an Effective, Inclusive School

Science.gov (United States)

Waldron, Nancy L.; McLeskey, James; Redd, Lacy

2011-01-01

Many schools are currently faced with the difficult task of including increasing numbers of students with disabilities and improving academic outcomes for these and other students who struggle to learn academic content. Recent research has shown that the principal is the key to ensuring that a school meets both of these goals and is both inclusive…

Critical Factors Explaining the Leadership Performance of High-Performing Principals

Science.gov (United States)

Hutton, Disraeli M.

2018-01-01

The study explored critical factors that explain leadership performance of high-performing principals and examined the relationship between these factors based on the ratings of school constituents in the public school system. The principal component analysis with the use of Varimax Rotation revealed that four components explain 51.1% of the…

School Principals' Job Satisfaction: The Effects of Work Intensification

Science.gov (United States)

Wang, Fei; Pollock, Katina; Hauseman, Cameron

2018-01-01

This study examines principals' job satisfaction in relation to their work intensification. Frederick Herzberg's two-factor theory was used to shed light on how motivating and maintenance factors affect principals' job satisfaction. Logistic multiple regressions were used in the analysis of survey data that were collected from 2,701 elementary and…

Measuring School Principals' Support for ICT Integration in Palermo, Italy

Science.gov (United States)

Polizzi, Gabriella

2011-01-01

School principals play an important role in managing media and technology integration into school teaching since they can foster the use of information communication technologies (ICT) at a strategic level, even supporting the introduction of media literacy education activities into teaching. Starting from a review on the role of principals'…

Tuning protein expression using synonymous codon libraries targeted to the 5' mRNA coding region

DEFF Research Database (Denmark)

Goltermann, Lise; Borch Jensen, Martin; Bentin, Thomas

2011-01-01

intermediate expression levels of green fluorescent protein in Escherichia coli. At least in one case, no apparent effect on protein stability was observed, pointing to RNA level effects as the principal reason for the observed expression differences. Targeting a synonymous codon library to the 5' coding...

Informing principal policy reforms in South Africa through data-based evidence

OpenAIRE

Gabrielle Wills

2015-01-01

In the past decade there has been a notable shift in South African education policy that raises the value of school leadership as a lever for learning improvements. Despite a growing discourse on school leadership, there has been a lack of empirical based evidence on principals to inform, validate or debate the efficacy of proposed policies in raising the calibre of school principals. Drawing on findings from a larger study to understand the labour market for school principals in South Africa...

Implementing Comprehensive School Health in Alberta, Canada: the principal's role.

Science.gov (United States)

Roberts, Erica; McLeod, Nicole; Montemurro, Genevieve; Veugelers, Paul J; Gleddie, Doug; Storey, Kate E

2016-12-01

Comprehensive School Health (CSH) is an internationally recognized framework that moves beyond the individual to holistically address school health, leading to the development of health-enhancing behaviors while also improving educational outcomes. Previous research has suggested that principal support for CSH implementation is essential, but this role has yet to be explored. Therefore, the purpose of this research was to examine the role of the principal in the implementation of a CSH project aimed at creating a healthy school culture. This research was guided by the grounded ethnography method. Semi-structured interviews were conducted with APPLE School principals (n = 29) to qualitatively explore their role in creating a healthy school culture. A model consisting of five major themes emerged, suggesting that the principal played a fluid role throughout the CSH implementation process. Principals (i) primed the cultural change; (ii) communicated the project's importance to others; (iii) negotiated concerns and collaboratively planned; (iv) held others accountable to the change, while enabling them to take ownership and (v) played an underlying supportive role, providing positive recognition and establishing ongoing commitment. This research provides recommendations to help establish effective leadership practices in schools, conducive to creating a healthy school culture. © The Author 2015. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

The Profile of Intrapreneurship Leadership of Vocational High School Principals

Directory of Open Access Journals (Sweden)

Husaini Usman

2016-02-01

Full Text Available The implementation of the School Integrated Development (SID in the Vocational High School (VHS is quite ideal, but much of its succes depends on the activity in the VHS itself. The implementation of the SID in the VHS Bandung demonstrates the leadership style that tends to be authoritarian does not represent the intrapreneurship leadership characteristics. This conclusion shows 21 characteristics of intrapreneurship leadership with an acronym of Teknik. The training materials for candidates of VHS principals should include intrapreneurship leadership concept based on belief and piety, and science, technology, and art as one of its main subject matters

Targeting Siah2 as Novel Therapy for Metastatic Prostate Cancer

Science.gov (United States)

2017-12-01

deprivation therapy (ADT) or androgen receptor (AR) pathway inhibition (ARPI) but eventually develops into lethal castration resistance prostate cancer ...AWARD NUMBER: W81XWH-14-1-0553 TITLE: Targeting Siah2 as Novel Therapy for Metastatic Prostate Cancer PRINCIPAL INVESTIGATOR: Martin Gleave...Siah2 as Novel Therapy for Metastatic Prostate Cancer 5b. GRANT NUMBER W81XWH-14-1-0553 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) Martin Gleave 5d

Spatial control of groundwater contamination, using principal

Indian Academy of Sciences (India)

Spatial control of groundwater contamination, using principal component analysis ... anthropogenic (agricultural activities and domestic wastewaters), and marine ... The PC scores reflect the change of groundwater quality of geogenic origin ...

Nuclease Target Site Selection for Maximizing On-target Activity and Minimizing Off-target Effects in Genome Editing

Science.gov (United States)

Lee, Ciaran M; Cradick, Thomas J; Fine, Eli J; Bao, Gang

2016-01-01

The rapid advancement in targeted genome editing using engineered nucleases such as ZFNs, TALENs, and CRISPR/Cas9 systems has resulted in a suite of powerful methods that allows researchers to target any genomic locus of interest. A complementary set of design tools has been developed to aid researchers with nuclease design, target site selection, and experimental validation. Here, we review the various tools available for target selection in designing engineered nucleases, and for quantifying nuclease activity and specificity, including web-based search tools and experimental methods. We also elucidate challenges in target selection, especially in predicting off-target effects, and discuss future directions in precision genome editing and its applications. PMID:26750397

A Review of Singapore Principals' Leadership Qualities, Styles, and Roles

Science.gov (United States)

Ng, David Foo Seong; Nguyen, Dong Thanh; Wong, Benjamin Koon Siak; Choy, William Kim Weng

2015-01-01

Purpose: The purpose of this paper is to present a review of empirical studies on principal leadership in Singapore. It seeks to provide a general picture of Singapore principals' leadership qualities, styles, and roles. Design/methodology/approach: This is a systematic review of empirical studies, using a "bounded" approach with a focus…

Investing in Leadership: The District's Role in Managing Principal Turnover

Science.gov (United States)

Mascall, Blair; Leithwood, Kenneth

2010-01-01

This article presents the results of research into the impact of principal turnover on schools, and the ability of schools to mitigate the negative effects of frequent turnover by distributing leadership in the schools. The findings from this qualitative and quantitative analysis show that rapid principal turnover does indeed have a negative…

The Relationship between Principals' Transformational Leadership Behaviors and School Culture

Science.gov (United States)

Bolton, David A.

2011-01-01

This quantitative study looks at the relationship between a principals' transformational leadership behaviors and the culture of their school. The goal of the study is to determine if transformational leadership qualities have a positive impact on the culture present in a school. Congruency between the views of a principal and their staff will…

Assistant/Deputy Principals: What Are Their Perceptions of Their Role?

Science.gov (United States)

Shore, Kevin; Walshaw, Margaret

2018-01-01

The roles and aspirations of Assistant/Deputy Principals (AP/DPs) have received attention for a number of decades. In contrast to much of the reported research that either highlights the administrative and management tasks or foregrounds principal succession, we explore levels of satisfaction that play into DP/APs' interpretations of the realities…

PCA: Principal Component Analysis for spectra modeling

Science.gov (United States)

Hurley, Peter D.; Oliver, Seb; Farrah, Duncan; Wang, Lingyu; Efstathiou, Andreas

2012-07-01

The mid-infrared spectra of ultraluminous infrared galaxies (ULIRGs) contain a variety of spectral features that can be used as diagnostics to characterize the spectra. However, such diagnostics are biased by our prior prejudices on the origin of the features. Moreover, by using only part of the spectrum they do not utilize the full information content of the spectra. Blind statistical techniques such as principal component analysis (PCA) consider the whole spectrum, find correlated features and separate them out into distinct components. This code, written in IDL, classifies principal components of IRS spectra to define a new classification scheme using 5D Gaussian mixtures modelling. The five PCs and average spectra for the four classifications to classify objects are made available with the code.

Summer Principals'/Directors' Orientation Training Module.

Science.gov (United States)

Mata, Robert L.; Garcia, Richard L.

Intended to provide current or potential project principals/directors with the basic knowledge, skills, abilities, and sensitivities needed to manage a summer migrant school project in the local educational setting, this module provides instruction in the project management areas of planning, preparation, control, and termination. The module…

The Impact of Pay Satisfaction and School Achievement on High School Principals' Turnover Intentions

Science.gov (United States)

Tran, Henry

2017-01-01

In recent years, a principal supply shortage crisis has emerged in the USA. This problem has been exacerbated by an increase in principal departures, which has been found to be negatively related to school outcomes. While research exists on several determinants of principal turnover, any examination of the relationship between principals'…

The Effect of Trained Principals on the Professional (Self Development of Employees

Directory of Open Access Journals (Sweden)

Hariz Agic

2012-03-01

Full Text Available The matter election of principal in schools can sometimes becomea political issue. All political parties are interested in this position,especially the ones that are now in power. The work of a principalis a rather complex activity, especially during the time of transition,when teachers, who are managed by the principals, expectthe implementation of every outlined change and to achieve thegoals of educational reform. Principals often must struggle to superviseteachers and deal with difficulties, because during theirprofessional development they did not acquire basic competencyin management, or management in education. This article discussesresearch among the main participants in education (teachers,principals, and advisors and examines what kind of influenceeducation has on principals’ ability to provide leadership intimes of change. The results of this research show that leadershipin schools is more efficient if principals are more educated in disciplines such as management in education.

High-Need Schools in Australia: The Leadership of Two Principals

Science.gov (United States)

Gurr, David; Drysdale, Lawrie; Clarke, Simon; Wildy, Helen

2014-01-01

In this article, we report on our initial work with the International School Leadership Development Network. In doing so, we present two cases of principals leading high-need schools, and conclude with some key observations in relation to what is distinctive about leading these schools. The first case features a principal leading a suburban school…

Calibrating One's Moral Compass: How Principal Preparation Shapes School Leaders

Science.gov (United States)

Larsen, Donald E.; Derrington, Mary Lynne

2012-01-01

No textbook that an aspiring principal encounters in preparing for the role of school leader discusses what steps to follow when a member--or members--of the school staff challenge standards of professional judgment and moral rectitude. Instead, the most reliable guide at the principal's disposal may be the "moral compass" upon which the…

Examining Teachers' Motivation Level According to School Principals' Humor Styles

Science.gov (United States)

Recepoglu, Ergun; Kilinc, Ali Cagatay; Cepni, Osman

2011-01-01

The purpose of this research is to examine the motivation level of teachers according to school principals' humor styles. The humor styles survey and job motivation scale were used to gather data from 305 randomly selected teachers employed in primary schools in Karabuk. Results indicated that 141 of the teachers claimed school principal had…

Functional principal component analysis of glomerular filtration rate curves after kidney transplant.

Science.gov (United States)

Dong, Jianghu J; Wang, Liangliang; Gill, Jagbir; Cao, Jiguo

2017-01-01

This article is motivated by some longitudinal clinical data of kidney transplant recipients, where kidney function progression is recorded as the estimated glomerular filtration rates at multiple time points post kidney transplantation. We propose to use the functional principal component analysis method to explore the major source of variations of glomerular filtration rate curves. We find that the estimated functional principal component scores can be used to cluster glomerular filtration rate curves. Ordering functional principal component scores can detect abnormal glomerular filtration rate curves. Finally, functional principal component analysis can effectively estimate missing glomerular filtration rate values and predict future glomerular filtration rate values.

School Principals' Perceptions of Ethically Just Responses to a Teacher Sexting Vignette: Severity of Administrator Response, Principals' Personality, and Offender Gender and Race

Science.gov (United States)

Wagner, Kenneth

2012-01-01

Site level administrators make decisions during the course of a day that have ethical dimensions that challenge their personal values and ethics. This study examined the extent to which particular factors would affect principals' and vice principals' judgments of the ethicality of sanctions given a teacher who had been sending sexually…

Principals' Leadership Styles and Student Achievement

Science.gov (United States)

Harnish, David Alan

2012-01-01

Many schools struggle to meet No Child Left Behind's stringent adequate yearly progress standards, although the benchmark has stimulated national creativity and reform. The purpose of this study was to explore teacher perceptions of principals' leadership styles, curriculum reform, and student achievement to ascertain possible factors to improve…

Open source tracking and analysis of adult Drosophila locomotion in Buridan's paradigm with and without visual targets.

Directory of Open Access Journals (Sweden)

Julien Colomb

Full Text Available BACKGROUND: Insects have been among the most widely used model systems for studying the control of locomotion by nervous systems. In Drosophila, we implemented a simple test for locomotion: in Buridan's paradigm, flies walk back and forth between two inaccessible visual targets [1]. Until today, the lack of easily accessible tools for tracking the fly position and analyzing its trajectory has probably contributed to the slow acceptance of Buridan's paradigm. METHODOLOGY/PRINCIPAL FINDINGS: We present here a package of open source software designed to track a single animal walking in a homogenous environment (Buritrack and to analyze its trajectory. The Centroid Trajectory Analysis (CeTrAn software is coded in the open source statistics project R. It extracts eleven metrics and includes correlation analyses and a Principal Components Analysis (PCA. It was designed to be easily customized to personal requirements. In combination with inexpensive hardware, these tools can readily be used for teaching and research purposes. We demonstrate the capabilities of our package by measuring the locomotor behavior of adult Drosophila melanogaster (whose wings were clipped, either in the presence or in the absence of visual targets, and comparing the latter to different computer-generated data. The analysis of the trajectories confirms that flies are centrophobic and shows that inaccessible visual targets can alter the orientation of the flies without changing their overall patterns of activity. CONCLUSIONS/SIGNIFICANCE: Using computer generated data, the analysis software was tested, and chance values for some metrics (as well as chance value for their correlation were set. Our results prompt the hypothesis that fixation behavior is observed only if negative phototaxis can overcome the propensity of the flies to avoid the center of the platform. Together with our companion paper, we provide new tools to promote Open Science as well as the collection and

Principals' and Teachers' Perceptions of Efforts by Principals to Improve Teaching and Learning in Turkish Middle Schools

Science.gov (United States)

Bellibas, Mehmet Sükrü

2015-01-01

Contemporary research on instructional leadership has largely concerned itself with developing concrete instructional leadership models and investigating the association of such leadership practices with teaching and learning. Yet there is little research on how the internal school community reacts to the notion of principals influencing classroom…

In vivo Photoacoustic Imaging of Prostate Cancer Using Targeted Contrast Agent

Science.gov (United States)

2016-11-01

AD______________ AWARD NUMBER: W81XWH-14-1-0242 TITLE: In Vivo Photoacoustic Imaging of Prostate Cancer Using Targeted Contrast Agent PRINCIPAL...TITLE AND SUBTITLE In vivo Photoacoustic Imaging of Prostate Cancer Using T argeted Contrast Agent 5a. CONTRACT NUMBER W81XWH-14-1-0242 5b. GRANT...diagnose prostate cancer based on the near-infrared optical absorption of either endogenous tissue constituents or exogenous contrast agents . Although

L'infelicità del principe felice. Oscar Wilde e Tommaso Landolfi

Directory of Open Access Journals (Sweden)

Luca Federico

2015-12-01

Full Text Available Both Tommaso Landolfi’s education and his translations from Russian, French and German have inspired a number of comparative studies within these three linguistic areas. On the contrary, how Anglo-Irish literature influenced this writer’s artistic evolution has not yet been thoroughly explored. This article aims to explore the relationship between Landolfi and Oscar Wilde by comparing Landolfi’s Favola (1938 and Il principe infelice (1943 with a selection of Wilde’s short stories included in the collections Happy Prince and Other Tales (1888 and A House of Pomegranates (1891.

Cardiomyocyte microvesicles contain DNA/RNA and convey biological messages to target cells.

Directory of Open Access Journals (Sweden)

Anders Waldenström

Full Text Available BACKGROUND: Shedding microvesicles are membrane released vesicles derived directly from the plasma membrane. Exosomes are released membrane vesicles of late endosomal origin that share structural and biochemical characteristics with prostasomes. Microvesicles/exosomes can mediate messages between cells and affect various cell-related processes in their target cells. We describe newly detected microvesicles/exosomes from cardiomyocytes and depict some of their biological functions. METHODOLOGY/PRINCIPAL FINDINGS: Microvesicles/exosomes from media of cultured cardiomyocytes derived from adult mouse heart were isolated by differential centrifugation including preparative ultracentrifugation and identified by transmission electron microscopy and flow cytometry. They were surrounded by a bilayered membrane and flow cytometry revealed presence of both caveolin-3 and flotillin-1 while clathrin and annexin-2 were not detected. Microvesicle/exosome mRNA was identified and out of 1520 detected mRNA, 423 could be directly connected in a biological network. Furthermore, by a specific technique involving TDT polymerase, 343 different chromosomal DNA sequences were identified in the microvesicles/exosomes. Microvesicle/exosomal DNA transfer was possible into target fibroblasts, where exosomes stained for DNA were seen in the fibroblast cytosol and even in the nuclei. The gene expression was affected in fibroblasts transfected by microvesicles/exosomes and among 333 gene expression changes there were 175 upregulations and 158 downregulations compared with controls. CONCLUSIONS/SIGNIFICANCE: Our study suggests that microvesicles/exosomes released from cardiomyocytes, where we propose that exosomes derived from cardiomyocytes could be denoted "cardiosomes", can be involved in a metabolic course of events in target cells by facilitating an array of metabolism-related processes including gene expression changes.

A Phenomenological Narrative Study: Elementary Charter School Principals' Managerial Roles

Science.gov (United States)

Cetinkaya, Ahmet

2016-01-01

This study was a phenomenological narrative research investigating the managerial roles of elementary charter school principals. Managerial leadership practices were investigated under three categories personnel management, student management, and finance management. Elementary charter school principals provided positive feedback for having small…

Radar automatic target recognition (ATR) and non-cooperative target recognition (NCTR)

CERN Document Server

Blacknell, David

2013-01-01

The ability to detect and locate targets by day or night, over wide areas, regardless of weather conditions has long made radar a key sensor in many military and civil applications. However, the ability to automatically and reliably distinguish different targets represents a difficult challenge. Radar Automatic Target Recognition (ATR) and Non-Cooperative Target Recognition (NCTR) captures material presented in the NATO SET-172 lecture series to provide an overview of the state-of-the-art and continuing challenges of radar target recognition. Topics covered include the problem as applied to th

Spatial control of groundwater contamination, using principal ...

Indian Academy of Sciences (India)

probe into the spatial controlling processes of groundwater contamination, using principal component analysis (PCA). ... topography, soil type, depth of water levels, and water usage. Thus, the ... of effective sites for infiltration of recharge water.

The Relationship between Principals' Managerial Approaches and ...

African Journals Online (AJOL)

Nekky Umera

Egerton University, P. O. Box 16568, NAKURU KENYA bosirej@yahoo.com ... teacher and parental input while it was negatively correlated with the level of .... principal's attitude, gender qualifications, and leadership experience (Green,. 1999 ...

Assessment of School Principals' Reassignment Process

Science.gov (United States)

Sezgin-Nartgün, Senay; Ekinci, Serkan

2016-01-01

This study aimed to identify administrators' views related to the assessment of school principals' reassignment in educational organizations. The study utilized qualitative research design and the study group composed of 8 school administrators selected via simple sampling who were employed in the Bolu central district in 2014-2015 academic year.…

The Principal as Professional Development Leader

Science.gov (United States)

Lindstrom, Phyllis H.; Speck, Marsha

2004-01-01

Individual teachers have the greatest effect on student performance. Principals, as professional development leaders, are in the best position to provide teachers with the professional development strategies they need to improve skills and raise student achievement. This book guides readers through a step-by-step process to formulate, implement,…

STYLES OF DECISION MAKING AND MANAGEMENT AND DIMENSIONS OF PERSONALITY OF SCHOOL PRINCIPALS

Directory of Open Access Journals (Sweden)

Anita Azeska

2017-12-01

Full Text Available This paper explores preference to the style of decision making (managerial, analytical, conceptual and behavioural, (Alan Rowe, 1992, management styles (relationship-oriented leadership and management by objectives, (Fiedler, 1987 and personality traits (extraversion, neuroticism and psychoticism, (Eysenck, 1998. The convenience sample of 61 respondents (principals of primary and secondary schools from Macedonia were subjected to decision making style inventory (Decision Style Inventory - DSI of 20 claims, a questionnaire to assess the management style (Least preferred coworker - LPC composed of 18 bipolar adjectives, and a personality test (Eysenck Personality Questionnaire - EPQ composed of 90 items in the form of questions. Results show that schools lean towards directive style of decision making with a combination of democratic-participatory style that includes subordinates in the process of decision making. The results also demonstrate that school principals prefer management style motivated by relationships; they are more introverted and emotionally stable. The findings indicate a necessity for a new generation of managers who will be different from the traditional managers. It is evident that the future will require managers with leadership styles different from the traditional in Republic of Macedonia. Given that the school is a basic organisational cell on which the educational system of the country is based, the proposed findings present an occasion for developing new ideas and practices that may yield great results. This would increase the flexibility and adaptive capacity of the school as a modern organisation. Thus, these findings have practical implications as they may direct special training of principals in order to apply the best management style, or style that is most appropriate for certain situations, certainly through coordination of the desired profile of the principal and the business strategy, development and maturity of

Teaching Principal Components Using Correlations.

Science.gov (United States)

Westfall, Peter H; Arias, Andrea L; Fulton, Lawrence V

2017-01-01

Introducing principal components (PCs) to students is difficult. First, the matrix algebra and mathematical maximization lemmas are daunting, especially for students in the social and behavioral sciences. Second, the standard motivation involving variance maximization subject to unit length constraint does not directly connect to the "variance explained" interpretation. Third, the unit length and uncorrelatedness constraints of the standard motivation do not allow re-scaling or oblique rotations, which are common in practice. Instead, we propose to motivate the subject in terms of optimizing (weighted) average proportions of variance explained in the original variables; this approach may be more intuitive, and hence easier to understand because it links directly to the familiar "R-squared" statistic. It also removes the need for unit length and uncorrelatedness constraints, provides a direct interpretation of "variance explained," and provides a direct answer to the question of whether to use covariance-based or correlation-based PCs. Furthermore, the presentation can be made without matrix algebra or optimization proofs. Modern tools from data science, including heat maps and text mining, provide further help in the interpretation and application of PCs; examples are given. Together, these techniques may be used to revise currently used methods for teaching and learning PCs in the behavioral sciences.

Exploring the Relationships between Principals' Life Experiences and Transformational Leadership Behaviours

Science.gov (United States)

Nash, Steve; Bangert, Art

2014-01-01

The primary objective of this research study was to explore the relationships between principals' life experiences and their transformational leadership behaviours. Over 212 public school principals completed both the lifetime leadership inventory (LLI) and the multifactor leadership questionnaire (MLQ). Exploratory and confirmatory factor…

Integrating Data Transformation in Principal Components Analysis

KAUST Repository

Maadooliat, Mehdi; Huang, Jianhua Z.; Hu, Jianhua

2015-01-01

Principal component analysis (PCA) is a popular dimension reduction method to reduce the complexity and obtain the informative aspects of high-dimensional datasets. When the data distribution is skewed, data transformation is commonly used prior

Combating Principal-Agent Relationship Problems: Use of the Truth Revealing Incentive Mechanism

National Research Council Canada - National Science Library

Gates, Daniel R; Yoder, E. C; Coughlan, Peter J

2007-01-01

.... This report describes the principal-agent theory, identifies principal-agent problems in the current DoD contracting environment, discusses how the TRIM addresses these problems more effectively...

An Exploration of How Elementary School Principals Approach the Student Retention Decision Process

Science.gov (United States)

Martinez-Hicks, Laura M.

2012-01-01

This is a constructivist grounded theory study investigating how elementary principals approach the student retention decision process in their schools. Twenty-two elementary principals participated in the study using a selective or snowball sampling method. Principals worked in one of three districts in a mid-Atlantic state and had experience as…

The Audit of Principal Effectiveness: Instrumentation for Principalship Research. A Research Project Report.

Science.gov (United States)

Valentine, Jerry W.; Bowman, Michael L.

Using the literature and research on principal effectiveness as a foundation, the Audit of Principal Effectiveness was developed. Initially, 162 items forming 12 theoretical factors describing effective principal behavior were identified and sorted into two documents. The documents, each containing 81 items, were mailed to a total of 3,660…

Principal Component and Cluster Analysis as a Tool in the Assessment of Tomato Hybrids and Cultivars

Directory of Open Access Journals (Sweden)

G. Evgenidis

2011-01-01

Full Text Available Determination of germplasm diversity and genetic relationships among breeding materials is an invaluable aid in crop improvement strategies. This study assessed the breeding value of tomato source material. Two commercial hybrids along with an experimental hybrid and four cultivars were assessed with cluster and principal component analyses based on morphophysiological data, yield and quality, stability of performance, heterosis, and combining abilities. The assessment of commercial hybrids revealed a related origin and subsequently does not support the identification of promising offspring in their crossing. The assessment of the cultivars discriminated them according to origin and evolutionary and selection effects. On the Principal Component 1, the largest group with positive loading included, yield components, heterosis, general and specific combining ability, whereas the largest negative loading was obtained by qualitative and descriptive traits. The Principal Component 2 revealed two smaller groups, a positive one with phenotypic traits and a negative one with tolerance to inbreeding. Stability of performance was loaded positively and/or negatively. In conclusion, combing ability, yield components, and heterosis provided a mechanism for ensuring continued improvement in plant selection programs.

Fuzzy Genetic Algorithm Based on Principal Operation and Inequity Degree

Science.gov (United States)

Li, Fachao; Jin, Chenxia

In this paper, starting from the structure of fuzzy information, by distinguishing principal indexes and assistant indexes, give comparison of fuzzy information on synthesizing effect and operation of fuzzy optimization on principal indexes transformation, further, propose axiom system of fuzzy inequity degree from essence of constraint, and give an instructive metric method; Then, combining genetic algorithm, give fuzzy optimization methods based on principal operation and inequity degree (denoted by BPO&ID-FGA, for short); Finally, consider its convergence using Markov chain theory and analyze its performance through an example. All these indicate, BPO&ID-FGA can not only effectively merge decision consciousness into the optimization process, but possess better global convergence, so it can be applied to many fuzzy optimization problems.

WE-H-BRA-03: Development of a Model to Include the Evolution of Resistant Tumor Subpopulations Into the Treatment Optimization Process for Schedules Involving Targeted Agents in Chemoradiation Therapy

International Nuclear Information System (INIS)

Grassberger, C; Paganetti, H

2016-01-01

Purpose: To develop a model that includes the process of resistance development into the treatment optimization process for schedules that include targeted therapies. Further, to validate the approach using clinical data and to apply the model to assess the optimal induction period with targeted agents before curative treatment with chemo-radiation in stage III lung cancer. Methods: Growth of the tumor and its subpopulations is modeled by Gompertzian growth dynamics, resistance induction as a stochastic process. Chemotherapy induced cell kill is modeled by log-cell kill dynamics, targeted agents similarly but restricted to the sensitive population. Radiation induced cell kill is assumed to follow the linear-quadratic model. The validation patient data consist of a cohort of lung cancer patients treated with tyrosine kinase inhibitors that had longitudinal imaging data available. Results: The resistance induction model was successfully validated using clinical trial data from 49 patients treated with targeted agents. The observed recurrence kinetics, with tumors progressing from 1.4–63 months, result in tumor growth equaling a median volume doubling time of 92 days [34–248] and a median fraction of pre-existing resistance of 0.035 [0–0.22], in agreement with previous clinical studies. The model revealed widely varying optimal time points for the use of curative therapy, reaching from ∼1m to >6m depending on the patient’s growth rate and amount of pre-existing resistance. This demonstrates the importance of patient-specific treatment schedules when targeted agents are incorporated into the treatment. Conclusion: We developed a model including evolutionary dynamics of resistant sub-populations with traditional chemotherapy and radiation cell kill models. Fitting to clinical data yielded patient specific growth rates and resistant fraction in agreement with previous studies. Further application of the model demonstrated how proper timing of chemo

WE-H-BRA-03: Development of a Model to Include the Evolution of Resistant Tumor Subpopulations Into the Treatment Optimization Process for Schedules Involving Targeted Agents in Chemoradiation Therapy

Energy Technology Data Exchange (ETDEWEB)

Grassberger, C; Paganetti, H [Massachusetts General Hospital, Boston, MA (United States)

2016-06-15

Purpose: To develop a model that includes the process of resistance development into the treatment optimization process for schedules that include targeted therapies. Further, to validate the approach using clinical data and to apply the model to assess the optimal induction period with targeted agents before curative treatment with chemo-radiation in stage III lung cancer. Methods: Growth of the tumor and its subpopulations is modeled by Gompertzian growth dynamics, resistance induction as a stochastic process. Chemotherapy induced cell kill is modeled by log-cell kill dynamics, targeted agents similarly but restricted to the sensitive population. Radiation induced cell kill is assumed to follow the linear-quadratic model. The validation patient data consist of a cohort of lung cancer patients treated with tyrosine kinase inhibitors that had longitudinal imaging data available. Results: The resistance induction model was successfully validated using clinical trial data from 49 patients treated with targeted agents. The observed recurrence kinetics, with tumors progressing from 1.4–63 months, result in tumor growth equaling a median volume doubling time of 92 days [34–248] and a median fraction of pre-existing resistance of 0.035 [0–0.22], in agreement with previous clinical studies. The model revealed widely varying optimal time points for the use of curative therapy, reaching from ∼1m to >6m depending on the patient’s growth rate and amount of pre-existing resistance. This demonstrates the importance of patient-specific treatment schedules when targeted agents are incorporated into the treatment. Conclusion: We developed a model including evolutionary dynamics of resistant sub-populations with traditional chemotherapy and radiation cell kill models. Fitting to clinical data yielded patient specific growth rates and resistant fraction in agreement with previous studies. Further application of the model demonstrated how proper timing of chemo

Dealing with Crises: One Principal's Experience.

Science.gov (United States)

Foley, Charles F.

1986-01-01

The principal of Concord High School (New Hampshire) recounts the 1985-86 school year's four crises--the visits of teacher-astronaut Christa McAuliffe and Secretary of Education William Bennett, the shooting of a former student, and the Challenger space shuttle explosion. The greatest challenge was resuming the normal schedule and fielding media…

Principals' Transformational Leadership in School Improvement

Science.gov (United States)

Yang, Yingxiu

2013-01-01

Purpose: This paper aims to contribute experience and ideas of the transformational leadership, not only for the principal want to improve leadership himself (herself), but also for the school at critical period of improvement, through summarizing forming process and the problem during the course and key factors that affect the course.…

Islamitisch financieren tussen principes en realiteit

NARCIS (Netherlands)

Wolters, W.G.

2009-01-01

‘De financiële crisis zou niet hebben plaatsgevonden, als de wereld de principes van islamitisch bankieren en financieren zou hebben aangenomen.’ Dat was één van de kenmerkende reacties van de kant van de islamitische bankiers, in de laatste maanden van 2008. Toen begon de wereldwijde financiële

Restriction Theorem for Principal bundles in Arbitrary Characteristic

DEFF Research Database (Denmark)

Gurjar, Sudarshan

2015-01-01

The aim of this paper is to prove two basic restriction theorem for principal bundles on smooth projective varieties in arbitrary characteristic generalizing the analogues theorems of Mehta-Ramanathan for vector bundles. More precisely, let G be a reductive algebraic group over an algebraically...... closed field k and let X be a smooth, projective variety over k together with a very ample line bundle O(1). The main result of the paper is that if E is a semistable (resp. stable) principal G-bundle on X w.r.t O(1), then the restriction of E to a general, high multi-degree, complete-intersection curve...

Heterogeneous chromatin target model

International Nuclear Information System (INIS)

Watanabe, Makoto

1996-01-01

The higher order structure of the entangled chromatin fibers in a chromosome plays a key role in molecular control mechanism involved in chromosome mutation due to ionizing radiations or chemical mutagens. The condensed superstructure of chromatin is not so rigid and regular as has been postulated in general. We have proposed a rheological explanation for the flexible network system ('chromatin network') that consists of the fluctuating assembly of nucleosome clusters linked with supertwisting DNA in a chromatin fiber ('Supertwisting Particulate Model'). We have proposed a 'Heterosensitive Target Model' for cellular radiosensitivity that is a modification of 'Heterogeneous Target Model'. The heterogeneity of chromatin target is derived from the highly condensed organization of chromatin segments consist of unstable and fragile sites in the fluctuating assembly of nucleosome clusters, namely 'supranucleosomal particles' or 'superbeads'. The models have been principally supported by our electron microscopic experiments employing 'surface - spreading whole - mount technique' since 1967. However, some deformation and artifacts in the chromatin structure are inevitable with these electron microscopic procedures. On the contrary, the 'atomic force microscope (AFM)' can be operated in liquid as well as in the air. A living specimen can be examined without any preparative procedures. Micromanipulation of the isolated chromosome is also possible by the precise positional control of a cantilever on the nanometer scale. The living human chromosomes were submerged in a solution of culture medium and observed by AFM using a liquid immersion cell. The surface - spreading whole - mount technique was applicable for this observation. The particulate chromatin segments of nucleosome clusters were clearly observed within mitotic human chromosomes in a living hydrated condition. These findings support the heterogeneity of chromatin target in a living cell. (J.P.N.)

Relationship between Communication Competence and Conflict Management Styles of School Principals

Science.gov (United States)

Uzun, Tevfik; Ayik, Ahmet

2017-01-01

Purpose: Determining the relationship between communication competence and conflict management styles of school principals, according to teacher perceptions, is important for school principals to effectively manage and foster a positive school environment. Conflicts are inevitable in all types of schools. Managing conflicts and maintaining…

The Role of School Principals in Shaping Children's Values.

Science.gov (United States)

Berson, Yair; Oreg, Shaul

2016-12-01

Instilling values in children is among the cornerstones of every society. There is wide agreement that beyond academic teaching, schools play an important role in shaping schoolchildren's character, imparting in them values such as curiosity, achievement, benevolence, and citizenship. Despite the importance of this topic, we know very little about whether and how schools affect children's values. In this large-scale longitudinal study, we examined school principals' roles in the development of children's values. We hypothesized that relationships exist between principals' values and changes in children's values through the mediating effect of the school climate. To test our predictions, we collected data from 252 school principals, 3,658 teachers, and 49,401 schoolchildren. A multilevel structural-equation-modeling analysis yielded overall support for our hypotheses. These findings contribute to understanding the development of children's values and the far-reaching impact of leaders' values. They also demonstrate effects of schools on children beyond those on academic achievement.

Likelihood-based methods for evaluating principal surrogacy in augmented vaccine trials.

Science.gov (United States)

Liu, Wei; Zhang, Bo; Zhang, Hui; Zhang, Zhiwei

2017-04-01

There is growing interest in assessing immune biomarkers, which are quick to measure and potentially predictive of long-term efficacy, as surrogate endpoints in randomized, placebo-controlled vaccine trials. This can be done under a principal stratification approach, with principal strata defined using a subject's potential immune responses to vaccine and placebo (the latter may be assumed to be zero). In this context, principal surrogacy refers to the extent to which vaccine efficacy varies across principal strata. Because a placebo recipient's potential immune response to vaccine is unobserved in a standard vaccine trial, augmented vaccine trials have been proposed to produce the information needed to evaluate principal surrogacy. This article reviews existing methods based on an estimated likelihood and a pseudo-score (PS) and proposes two new methods based on a semiparametric likelihood (SL) and a pseudo-likelihood (PL), for analyzing augmented vaccine trials. Unlike the PS method, the SL method does not require a model for missingness, which can be advantageous when immune response data are missing by happenstance. The SL method is shown to be asymptotically efficient, and it performs similarly to the PS and PL methods in simulation experiments. The PL method appears to have a computational advantage over the PS and SL methods.

Transcript profiling of Elf5+/- mammary glands during pregnancy identifies novel targets of Elf5.

Directory of Open Access Journals (Sweden)

Renee L Rogers

Full Text Available BACKGROUND: Elf5, an epithelial specific Ets transcription factor, plays a crucial role in the pregnancy-associated development of the mouse mammary gland. Elf5(-/- embryos do not survive, however the Elf5(+/- mammary gland displays a severe pregnancy-associated developmental defect. While it is known that Elf5 is crucial for correct mammary development and lactation, the molecular mechanisms employed by Elf5 to exert its effects on the mammary gland are largely unknown. PRINCIPAL FINDINGS: Transcript profiling was used to investigate the transcriptional changes that occur as a result of Elf5 haploinsufficiency in the Elf5(+/- mouse model. We show that the development of the mouse Elf5(+/- mammary gland is delayed at a transcriptional and morphological level, due to the delayed increase in Elf5 protein in these glands. We also identify a number of potential Elf5 target genes, including Mucin 4, whose expression, is directly regulated by the binding of Elf5 to an Ets binding site within its promoter. CONCLUSION: We identify novel transcriptional targets of Elf5 and show that Muc4 is a direct target of Elf5, further elucidating the mechanisms through which Elf5 regulates proliferation and differentiation in the mammary gland.

Principal axis-based correspondence between multiple cameras for people tracking.

Science.gov (United States)

Hu, Weiming; Hu, Min; Zhou, Xue; Tan, Tieniu; Lou, Jianguang; Maybank, Steve

2006-04-01

Visual surveillance using multiple cameras has attracted increasing interest in recent years. Correspondence between multiple cameras is one of the most important and basic problems which visual surveillance using multiple cameras brings. In this paper, we propose a simple and robust method, based on principal axes of people, to match people across multiple cameras. The correspondence likelihood reflecting the similarity of pairs of principal axes of people is constructed according to the relationship between "ground-points" of people detected in each camera view and the intersections of principal axes detected in different camera views and transformed to the same view. Our method has the following desirable properties: 1) Camera calibration is not needed. 2) Accurate motion detection and segmentation are less critical due to the robustness of the principal axis-based feature to noise. 3) Based on the fused data derived from correspondence results, positions of people in each camera view can be accurately located even when the people are partially occluded in all views. The experimental results on several real video sequences from outdoor environments have demonstrated the effectiveness, efficiency, and robustness of our method.

Principal Hawaiian Islands Geoid Heights (GEOID96)

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — This 2' geoid height grid for the Principal Hawaiian Islands is distributed as a GEOID96 model. The computation used 61,000 terrestrial and marine gravity data held...

Identification of attractive drug targets in neglected-disease pathogens using an in silico approach.

Directory of Open Access Journals (Sweden)

Gregory J Crowther

Full Text Available BACKGROUND: The increased sequencing of pathogen genomes and the subsequent availability of genome-scale functional datasets are expected to guide the experimental work necessary for target-based drug discovery. However, a major bottleneck in this has been the difficulty of capturing and integrating relevant information in an easily accessible format for identifying and prioritizing potential targets. The open-access resource TDRtargets.org facilitates drug target prioritization for major tropical disease pathogens such as the mycobacteria Mycobacterium leprae and Mycobacterium tuberculosis; the kinetoplastid protozoans Leishmania major, Trypanosoma brucei, and Trypanosoma cruzi; the apicomplexan protozoans Plasmodium falciparum, Plasmodium vivax, and Toxoplasma gondii; and the helminths Brugia malayi and Schistosoma mansoni. METHODOLOGY/PRINCIPAL FINDINGS: Here we present strategies to prioritize pathogen proteins based on whether their properties meet criteria considered desirable in a drug target. These criteria are based upon both sequence-derived information (e.g., molecular mass and functional data on expression, essentiality, phenotypes, metabolic pathways, assayability, and druggability. This approach also highlights the fact that data for many relevant criteria are lacking in less-studied pathogens (e.g., helminths, and we demonstrate how this can be partially overcome by mapping data from homologous genes in well-studied organisms. We also show how individual users can easily upload external datasets and integrate them with existing data in TDRtargets.org to generate highly customized ranked lists of potential targets. CONCLUSIONS/SIGNIFICANCE: Using the datasets and the tools available in TDRtargets.org, we have generated illustrative lists of potential drug targets in seven tropical disease pathogens. While these lists are broadly consistent with the research community's current interest in certain specific proteins, and suggest

Beyond Buses, Boilers, and Books: Instructional Support Takes Center Stage for Principal Supervisors

Science.gov (United States)

Syed, Sarosh

2014-01-01

Denver Public Schools, one of 14 districts that receive funding from The Wallace Foundation to improve principal effectiveness, is also one of a number of districts around the country emphasizing the development of principals' managers in the central office. The principal's job has changed over the last decade, going from a role that revolved…

Obstacles and Opportunities for Principals' Professional Development in Small K-8 School Districts

Science.gov (United States)

Narro, Laurie Irene

2011-01-01

The role of the principal is a demanding one. Many principals report that they don't believe they have the necessary training to act as a manager, instructional and transformational leader. Yet many principals do not avail themselves to ongoing professional development. It is for that reason that this study was undertaken: to discover the…

Principals in Partnership with Math Coaches

Science.gov (United States)

Grant, Catherine Miles; Davenport, Linda Ruiz

2009-01-01

One of the most promising developments in math education is the fact that many districts are hiring math coaches--also called math resource teachers, math facilitators, math lead teachers, or math specialists--to assist elementary-level teachers with math instruction. What must not be lost, however, is that principals play an essential role in…

Principal Instructional Leadership in Taiwan: Lessons from Two Decades of Research

Science.gov (United States)

Pan, Hui-Ling Wendy; Nyeu, Fong-Yee; Chen, June S.

2015-01-01

Purpose: The purpose of this paper is to examine how instructional leadership, a concept imported from Western scholarship, has been conceptualized in the Taiwanese context and how principal instructional leadership is realized in schools. The development trajectory of principal instructional leadership is delineated by examining empirical studies…

School Principals' Evaluations of Their Instructional Leadership Behaviours: Realities vs. Ideals

Science.gov (United States)

Kalman, Mahmut; Arslan, Mustafa Cüneyt

2016-01-01

The purpose of the current study was to examine primary and middle school principals' evaluations of their own instructional leadership behaviours, and thereby pay closer attention to the ideal instructional leadership behaviours suggested in the related literature and the realities of principals' instructional leadership behaviours. Although…

Principals Responding to Constant Pressure: Finding a Source of Stress Management

Science.gov (United States)

Wells, Caryn M.

2013-01-01

This conceptual article presents a review of the research concerning the stress level of principals over the past three decades, with emphasis on the occupational stress that principals encounter because of heightened accountability and expectations for student achievement. Mindfulness meditation, as a stress management intervention, provides the…

Detecting Market Transitions and Energy Futures Risk Management Using Principal Components

NARCIS (Netherlands)

Borovkova, S.A.

2006-01-01

An empirical approach to analysing the forward curve dynamics of energy futures is presented. For non-seasonal commodities-such as crude oil-the forward curve is well described by the first three principal components: the level, slope and curvature. A principal component indicator is described that

Centredale Manor Superfund Site in Rhode Island included on EPA List of Targeted for Immediate Attention

Science.gov (United States)

Today, the U.S. Environmental Protection Agency released the list of Superfund sites that Administrator Pruitt has targeted for immediate and intense attention. The Centredale Manor Restoration Project superfund site is one of the 21 sites on the list.