Sample records for primary flow structures

  1. Influence of flow properties on a structure of a mineral wool primary layer

    Bajcar, Tom; Blagojevic, Bogdan; Sirok, Brane; Dular, Matevz [Faculty of Mechanical Engineering, University of Ljubljana, Askerceva 6, SI - 1000 Ljubljana (Slovenia)


    Mineral wool primary layer formation is influenced by the aerodynamic characteristics of the blow-away airflow and the secondary surrounding airflow. The distribution of mineral wool fibres in the primary layer was determined experimentally using a computer-aided visualization method. The flow properties in the region where the primary layer is formed were analysed. Numerical simulations with experiment-based boundary conditions were performed. The numerically obtained profile of mineral wool thickness at the collection chamber outlet agreed with the results of the experiment. Presented numerical model confirms that the forming of the primary layer is significantly dependent on local aerodynamic characteristic of the airflow in the collection chamber. Interaction between the local anomalies on the forming layer and the corresponding aerodynamic effects in the surrounding region was also analysed. (author)

  2. Primary vesicles, vesicle-rich segregation structures and recognition of primary and secondary porosities in lava flows from the Paraná igneous province, southern Brazil

    Barreto, Carla Joana S.; de Lima, Evandro F.; Goldberg, Karin


    This study focuses on a volcanic succession of pāhoehoe to rubbly lavas of the Paraná-Etendeka Province exposed in a single road profile in southernmost Brazil. This work provides an integrated approach for examining primary vesicles and vesicle-rich segregation structures at the mesoscopic scale. In addition, this study provides a quantitative analysis of pore types in thin section. We documented distinct distribution patterns of vesicle and vesicle-rich segregation structures according to lava thickness. In compound pāhoehoe lavas, the cooling allows only vesicles (primary porosity, while hydrothermal alteration and tectonic fracturing are the main processes that generated secondary porosity. Although several forms of porosity were created in the basaltic lava flows, the precipitation of secondary minerals within the pores has tended to reduce the original porosities. Late-stage fractures could create efficient channel networks for possible hydrocarbon/groundwater migration and entrapment owing to their ability to connect single pores. Quantitative permeability data should be gathered in future studies to confirm the potential of these lavas for store hydrocarbons or groundwater.

  3. Flow structure in a can-type model gas turbine combustor. 1st report. ; Flow field in a primary zone. Kangata gas turbine nensho ki nai no nagare kozo. dai ippo. ; Mizu model jikken ni yoru nagare moyo

    Ikeda, Y.; Hosokawa, S. (Kobe Univ., Kobe (Japan). Graduate School); Nakajima, T. (Kobe Univ., Kobe (Japan). Faculty of Engineering)


    Recirculating vortex is composed of a strong swirl flow from the swirler and a jet flow from the liner wall, and plays the roles of fuel-air mixing, combustion, and flame stabilization. Optimum recirculating vortex for the load range is desired to be formed to decrease NO {sub x} production. The flow structure of the recirculating vortex in the primary zone and the flow near the combustor inlet measured using developed 2 types of small fiber LDV {prime} s are reported. The recirculating vortex formed in the primary zone becomes less with the increase in the momentum ratio, and moves to upstream and liner wall side. In addition, the velocity in the direction of swirl is accelerated. The liner jet is bent to the swirling direction when it comes out of the exit, and has a large velocity in the swirling direction. A toroidal vortex with a strong velocity in the swirling direction is formed near the center of the combustor. This blockades the flow from the swirler. The recirculating vortex has its effect as far as up to the upstream of the combustor inlet. 13 refs., 11 figs., 3 tabs.

  4. Structural power flow measurement

    Falter, K.J.; Keltie, R.F.


    Previous investigations of structural power flow through beam-like structures resulted in some unexplained anomalies in the calculated data. In order to develop structural power flow measurement as a viable technique for machine tool design, the causes of these anomalies needed to be found. Once found, techniques for eliminating the errors could be developed. Error sources were found in the experimental apparatus itself as well as in the instrumentation. Although flexural waves are the carriers of power in the experimental apparatus, at some frequencies longitudinal waves were excited which were picked up by the accelerometers and altered power measurements. Errors were found in the phase and gain response of the sensors and amplifiers used for measurement. A transfer function correction technique was employed to compensate for these instrumentation errors.

  5. Interstitial fluid flow of alveolar primary septa after pneumonectomy.

    Haber, Shimon; Weisbord, Michal; Mishima, Michiaki; Mentzer, Steve J; Tsuda, Akira


    Neoalveolation is known to occur in the remaining lung after pneumonectomy. While compensatory lung growth is a complex process, stretching of the lung tissue appears to be crucial for tissue remodeling. Even a minute shear stress exerted on fibroblasts in the interstitial space is known to trigger cell differentiation into myofibroblast that are essential to building new tissues. We hypothesize that the non-uniform motion of the primary septa due to their heterogeneous mechanical properties under tidal breathing induces a spatially unique interstitial flow and shear stress distribution in the interstitial space. This may in turn trigger pulmonary fibroblast differentiation and neoalveolation. In this study, we developed a theoretical basis for how cyclic motion of the primary septal walls with heterogeneous mechanical properties affects the interstitial flow and shear stress distribution. The velocity field of the interstitial flow was expressed by a Fourier (complex) series and its leading term was considered to induce the basic structure of stress distribution as long as the dominant length scale of heterogeneity is the size of collapsed alveoli. We conclude that the alteration of mechanical properties of the primary septa caused by pneumonectomy can develop a new interstitial flow field, which alters the shear stress distribution. This may trigger the differentiation of resident fibroblasts, which may in turn induce spatially unique neoalveolation in the remaining lung. Our example illustrates that the initial forming of new alveoli about half the size of the original ones. Copyright © 2016. Published by Elsevier Ltd.

  6. Fractal Structure of Debris Flow

    LI Yong; LIU Jingjing; HU Kaiheng; CHEN Xiaoqing


    One of the most remarkable characteristics of debris flow is the competence for supporting boulders on the surface of flow, which strongly suggests that there should be some structure in the fluid body. This paper analyzed the grain compositions from various samples of debris flows and then revealed the fractal structure. Specifically, the fractality holds in three domains that can be respectively identified as the slurry, matrix, and the coarse content. Furthermore, the matrix fractal, which distinguishes debris flow from other kinds of flows, involves a hierarchical structure in the sense that it might contain ever increasing grains while the total range of grain size increases. It provides a possible mechanism for the boulder suspension.

  7. Integrated flow field (IFF) structure

    Pien, Shyhing M. (Inventor); Warshay, Marvin (Inventor)


    The present disclosure relates in part to a flow field structure comprising a hydrophilic part and a hydrophobic part communicably attached to each other via a connecting interface. The present disclosure further relates to electrochemical cells comprising the aforementioned flow fields.

  8. Primary volcanic structures from a type section of Deccan Trap flows around Narsingpur–Harrai–Amarwara, central India: Implications for cooling history

    Piyali Sengupta; Arijit Ray


    Field investigations of the Deccan Trap lava sequence along a 70 km traverse in the Narsingpur–Harrai–Amarwara area of central India indicate twenty lava flows comprising a total thickness of around 480m. Primary volcanic structures like vesicles and cooling joints are conspicuous in this volcanic succession and are used to divide individual flows into three well-defined zones namely the lower colonnade zone, entablature zone, and the upper colonnade zone. The variable nature of these structural zones is used for identification and correlation of lava flows in the field. For twenty lava flows, the thicknesses of upper colonnade zones of eight flows are ∼5m while those of eight other flows are ∼8m each. The thicknesses of upper colonnade zones of remaining four flows could not be measured in the field. Using the thicknesses of these upper colonnade zones and standard temperature-flow thickness-cooling time profiles for lava pile, the total cooling time of these sixteen Deccan Trap lava flows has been estimated at 12 to 15 years.

  9. Structure - Riverine Flow Structure (Dike/Wingdam)

    Army Corps of Engineers, Department of the Army, Department of Defense — A natural or man-made flow (or sediment) control structure in a water course or water body such as a dike or weir. This feature should not be used to model a levee....

  10. Control structures for flow process

    Mircea Dulău


    Full Text Available In the industrial domain, a large number of applications is covered by slow processes, including the flow, the pressure, the temperature and the level control. Each control system must be treated in steady and dynamic states and from the point of view of the possible technical solutions. Based on mathematical models of the processes and design calculations, PC programs allow simulation and the determination of the control system performances.The paper presents a part of an industrial process with classical control loops of flow and temperature. The mathematical model of the flow control process was deducted, the control structure, based on experimental criterions, was designed and the version witch ensure the imposed performances was chosen. Using Matlab, the robustness performances were studied.

  11. Structure and organization of primary care.

    Lember, M.; Cartier, T.; Bourgueil, Y.; Dedeu, T.; Hutchinson, A.; Kringos, D.


    The way primary care is structured establishes important conditions for both the process of care and its outcomes. In this chapter, the structure of primary care will be discussed according to three dimensions: governance, economic conditions and workforce development. Governance refers to the visi

  12. Structure and organization of primary care.

    Lember, M.; Cartier, T.; Bourgueil, Y.; Dedeu, T.; Hutchinson, A.; Kringos, D.


    The way primary care is structured establishes important conditions for both the process of care and its outcomes. In this chapter, the structure of primary care will be discussed according to three dimensions: governance, economic conditions and workforce development. Governance refers to the

  13. Generalized primary/secondary flow analysis of viscous flow around bodies at incidence

    Govindan, T. R.; Briley, W. R.; Chang, Ming-Shun


    Generalized primary/secondary flow equations, which are an approximation to the Navier-Stokes equations, have been utilized to compute the three-dimensional viscous flow around bodies at incidence. Two features central to the approximations in the primary/secondary flow equations are a locally specified primary flow direction and a decomposition of the secondary velocity field. For the flow around a body at incidence, the local primary flow direction is aligned with streamlines for the potential flow around the body at zero degrees incidence. A sequentially decoupled implicit algorithm exploits the form of the primary/secondary flow equations for fast run times. Computed solutions for flow around an ogive cylinder at incidence and an unappended submarine hull in drift have been presented. These solutions show the generation of strong lee-side vortices which are a source of propulsor inlet distortion and a side-force on the body. Computed solutions agree well with available experimental data. The combined efficiency and accuracy of the approximate equations and solution algorithm make this approach attractive for computing viscous flow around bodies at incidence.

  14. Primary structural dynamics in graphite

    Schaefer, Sascha; Liang Wenxi; Zewail, Ahmed H, E-mail: [Physical Biology Center for Ultrafast Science and Technology, Arthur Amos Noyes Laboratory of Chemical Physics, California Institute of Technology, Pasadena, CA 91125 (United States)


    The structural dynamics of graphite and graphene are unique, because of the selective coupling between electron and lattice motions and hence the limit on electric and electro-optic properties. Here, we report on the femtosecond probing of graphite films (1-3 nm) using ultrafast electron crystallography in the transmission mode. Two time scales are observed for the dynamics: a 700 fs initial decrease in diffraction intensity due to lattice phonons in optically dark regions of the Brillouin zone, followed by a 12 ps decrease due to phonon thermalization near the {Gamma} and K regions. These results indicate the non-equilibrium distortion of the unit cells at early time and the subsequent role of long-wavelength atomic motions in the thermalization process. Theory and experiment are now in agreement regarding the nature of nuclear motions, but the results suggest that potential change plays a role in the lateral dynamics of the lattice.

  15. Two Primary Standards for Low Flows of Gases.

    Berg, Robert F; Tison, Stuart A


    We describe two primary standards for gas flow in the range from 0.1 to 1000 μmol/s. (1 μmol/s ≅ 1.3 cm(3)/min at 0 °C and 1 atmosphere.) The first standard is a volumetric technique in which measurements of pressure, volume, temperature, and time are recorded while gas flows in or out of a stainless steel bellows at constant pressure. The second standard is a gravimetric technique. A small aluminum pressure cylinder supplies gas to a laminar flow meter, and the integrated throughput of the laminar flow meter is compared to the weight decrease of the cylinder. The two standards, which have standard uncertainties of 0.019 %, agree to within combined uncertainties with each other and with a third primary standard at NIST based on pressure measurements at constant volume.

  16. Air Ejector Pumping Enhancement Through Pulsing Primary Flow


    CFD ) analysis show that pulsing the primary jet flow, an active metho of flow control, improved ejector performance. The physics of this improvement...without an entrance shape was found to be still reasonably efficient. Both experiments and Computer Fluid Dynamics( CFD ) analysis show that pulsing the...other shapes. A tube without an entrance shape was found to be still reasonably efficient. Both experiments and Computer Fluid Dynamics( CFD ) analysis

  17. Oscillatory fluid flow influences primary cilia and microtubule mechanics.

    Espinha, Lina C; Hoey, David A; Fernandes, Paulo R; Rodrigues, Hélder C; Jacobs, Christopher R


    Many tissues are sensitive to mechanical stimuli; however, the mechanotransduction mechanism used by cells remains unknown in many cases. The primary cilium is a solitary, immotile microtubule-based extension present on nearly every mammalian cell which extends from the basal body. The cilium is a mechanosensitive organelle and has been shown to transduce fluid flow-induced shear stress in tissues, such as the kidney and bone. The majority of microtubules assemble from the mother centriole (basal body), contributing significantly to the anchoring of the primary cilium. Several studies have attempted to quantify the number of microtubules emanating from the basal body and the results vary depending on the cell type. It has also been shown that cellular response to shear stress depends on microtubular integrity. This study hypothesizes that changing the microtubule attachment of primary cilia in response to a mechanical stimulus could change primary cilia mechanics and, possibly, mechanosensitivity. Oscillatory fluid flow was applied to two different cell types and the microtubule attachment to the ciliary base was quantified. For the first time, an increase in microtubules around primary cilia both with time and shear rate in response to oscillatory fluid flow stimulation was demonstrated. Moreover, it is presented that the primary cilium is required for this loading-induced cellular response. This study has demonstrated a new role for the cilium in regulating alterations in the cytoplasmic microtubule network in response to mechanical stimulation, and therefore provides a new insight into how cilia may regulate its mechanics and thus the cells mechanosensitivity.

  18. Structure and function in flow networks

    Rubido, Nicolás; Baptista, Murilo S


    This Letter presents a unified approach for the fundamental relationship between structure and function in flow networks by solving analytically the voltages in a resistor network, transforming the network structure to an effective all-to-all topology, and then measuring the resultant flows. Moreover, it defines a way to study the structural resilience of the graph and to detect possible communities.

  19. Primary structure of hemocyanin from Palinurus vulgaris

    Jekel, PA; Neuteboom, B; Beintema, JJ


    The primary structure of hemocyanin from the spiny lobster Palinurus vulgaris was determined using a mixture of at least four slightly different subunits. Heterogeneities were observed in 32 (5%) of the positions. The amino acid sequence differs at about 20% of the positions from that of subunit a o

  20. Fluid dynamics in airway bifurcations: I. Primary flows.

    Martonen, T B; Guan, X; Schreck, R M


    The subject of fluid dynamics within human airways is of great importance for the risk assessment of air pollutants (inhalation toxicology) and the targeted delivery of inhaled pharmacologic drugs (aerosol therapy). As cited herein, experimental investigations of flow patterns have been performed on airway models and casts by a number of investigators. We have simulated flow patterns in human lung bifurcations and compared the results with the experimental data of Schreck (1972). The theoretical analyses were performed using a third-party software package, FIDAP, on the Cray T90 supercomputer. This effort is part of a systematic investigation where the effects of inlet conditions, Reynolds numbers, and dimensions and orientations of airways were addressed. This article focuses on primary flows using convective motion and isovelocity contour formats to describe fluid dynamics; subsequent articles in this issue consider secondary currents (Part II) and localized conditions (Part III). The agreement between calculated and measured results, for laminar flows with either parabolic or blunt inlet conditions to the bifurcations, was very good. To our knowledge, this work is the first to present such detailed comparisons of theoretical and experimental flow patterns in airway bifurcations. The agreement suggests that the methodologies can be employed to study factors affecting airflow patterns and particle behavior in human lungs.

  1. Beyond lognormal inequality: The Lorenz Flow Structure

    Eliazar, Iddo


    Observed from a socioeconomic perspective, the intrinsic inequality of the lognormal law happens to manifest a flow generated by an underlying ordinary differential equation. In this paper we extend this feature of the lognormal law to a general "Lorenz Flow Structure" of Lorenz curves-objects that quantify socioeconomic inequality. The Lorenz Flow Structure establishes a general framework of size distributions that span continuous spectra of socioeconomic states ranging from the pure-communism extreme to the absolute-monarchy extreme. This study introduces and explores the Lorenz Flow Structure, analyzes its statistical properties and its inequality properties, unveils the unique role of the lognormal law within this general structure, and presents various examples of this general structure. Beyond the lognormal law, the examples include the inverse-Pareto and Pareto laws-which often govern the tails of composite size distributions.

  2. Coherent structures in transitional pipe flow

    Hellström, Leo H. O.; Ganapathisubramani, Bharathram; Smits, Alexander J.


    Transition to turbulence in pipe flow is investigated experimentally using a temporally resolved dual-plane particle image velocimetry approach, at a Reynolds number of 3440. The flow is analyzed using proper orthogonal decomposition and it is shown that the flow can be divided into two regions: a pseudolaminar region governed by the presence of azimuthally steady traveling waves, and turbulent slugs. The evolution of the structures within the slugs is identified by using the temporally resolved data along with the dual-plane velocity field. These structures are shown to be remarkably similar to the large-scale motions found in fully turbulent flows, with a streamwise and spatiotemporal extent about four pipe radii. The transition between structures is characterized by the detachment and decay of an old structure and the initiation of a new structure at the wall.

  3. Primary structure and configuration of tea polysaccharide

    ZHOU Peng; XIE Mingyong; NIE Shaoping; WANG Xiaoru


    The monosaccharide composition of a tea polysaccharide(TGC)was determined by GC-MS method.Furthermore,the primary structure of tea polysaccharide and its configuration in the aqueous solution were investigated utilizing a combination of classical chemical methods and modern instrumental techniques including GC-MS,Proton NMR,UV and CD.The results indicate that TGC consists of 6 monosaccharides: Rha,Ara,Xyl,Glu,Man and Gal.The configuration of TGC in water solution is proposed to be an ordered helix.The possible primary structure of TGC was outlined as below: the basic structure of the main chain consists of Rha,Glu and Gal units.All three monosaccharides can potentially be connected to branch chains consisting of mainly Ara,and the linkages could be in β1 →2,β1 →3,β2→3 forms.When branch chain is absent in the basic structure of the main chain the linkage consists of only β1→3; Xyl exists at the terminal end of either the main chain or the branch chain with β1 → linkage.

  4. Flow and scour around vertical submerged structures



    The safety of the foundations of submerged hydraulic structures due to excessive local scour is threatened by the erosive action of the waves and currents passing around these structures. Fish and aquatic habitat is seriously affected due to the modification of the flow field caused by these submerged structures. Hence, the problems of flow characteristics and erosion around submerged structures were investigated by various researchers. A comprehensive discussion of the investigations on flow characteristics and local scour due to steady currents and waves around vertical submerged structures are presented, which comprises scour process, dimensional analysis, parameters influencing scour, temporal evolution of scour, flow field, flow visualization techniques, variation of bed shear stress, scour depth determination formulas and scour countermeasures.Although past investigations establish the effect of various parameters on scour around vertical submerged structures for live and clear water condition, yet further studies are required to analyze the scour around group of submerged structures for various bed sediments, understand the flow physics around the group and upscale the model results for the prototype.

  5. Coherent flow structures at earth's surface

    Venditti, J.G; Best, J.L; Church, M; Hardy, R.J


    This book reviews the recent progress in the study of the turbulent flows that sculpt the Earth's surface, focusing in particular on the organized structures that have been identified in recent years...

  6. Characteristic flow patterns generated by macrozoobenthic structures

    Friedrichs, M.; Graf, G.


    A laboratory flume channel, equipped with an acoustic Doppler flow sensor and a bottom scanning laser, was used for detailed, non-intrusive flow measurements (at 2 cm s - 1 and 10 cm s - 1 ) around solitary biogenic structures, combined with high-resolution mapping of the structure shape and position. The structures were replicates of typical macrozoobenthic species commonly found in the Mecklenburg Bight and with a presumed influence on both, the near-bed current regime and sediment transport dynamics: a worm tube, a snail shell, a mussel, a sand mound, a pit, and a cross-stream track furrow. The flow was considerably altered locally by the different protruding structures (worm tube, snail, mussel and mound). They reduced the horizontal approach velocity by 72% to 79% in the wake zone at about 1-2 cm height, and the flow was deflected around the structures with vertical and lateral velocities of up to 10% and 20% of the free-stream velocity respectively in a region adjacent to the structures. The resulting flow separation (at flow Reynolds number of about 4000 and 20,000 respectively) divided an outer deflection region from an inner region with characteristic vortices and the wake region. All protruding structures showed this general pattern, but also produced individual characteristics. Conversely, the depressions (track and pit) only had a weak influence on the local boundary layer flow, combined with a considerable flow reduction within their cavities (between 29% and 53% of the free-stream velocity). A longitudinal vortex formed, below which a stagnant space was found. The average height affected by the structure-related mass flow rate deficit for the two velocities was 1.6 cm and 1.3 cm respectively (80% of height and 64%) for the protruding structures and 0.6 cm and 0.9 cm (90% and 127% of depth) for the depressions. Marine benthic soft-bottom macrozoobenthos species are expected to benefit from the flow modifications they induce, particularly in terms of

  7. Network structure of inter-industry flows

    McNerney, James; Silverberg, Gerald


    We study the structure of inter-industry relationships using networks of money flows between industries in 20 national economies. We find these networks vary around a typical structure characterized by a Weibull link weight distribution, exponential industry size distribution, and a common community structure. The community structure is hierarchical, with the top level of the hierarchy comprising five industry communities: food industries, chemical industries, manufacturing industries, service industries, and extraction industries.

  8. Network structure of subway passenger flows

    Xu, Qi; Bai, Yun


    The results of transportation infrastructure network analyses have been used to analyze complex networks in a topological context. However, most modeling approaches, including those based on complex network theory, do not fully account for real-life traffic patterns and may provide an incomplete view of network functions. This study utilizes trip data obtained from the Beijing Subway System to characterize individual passenger movement patterns. A directed weighted passenger flow network was constructed from the subway infrastructure network topology by incorporating trip data. The passenger flow networks exhibit several properties that can be characterized by power-law distributions based on flow size, and log-logistic distributions based on the fraction of boarding and departing passengers. The study also characterizes the temporal patterns of in-transit and waiting passengers and provides a hierarchical clustering structure for passenger flows. This hierarchical flow organization varies in the spatial doma...


    WANG Chao; YU Ji-yu; WANG Pei-fang; GUO Peng-cheng


    Aquatic vegetation can influence the transport of sediment and contaminants by changing the mean velocity and turbulent flow structure in channels. It is important to understand the hydraulics of the flows over vegetation in order to manage fluvial processes. Experiments in an open-channel flume with natural vegetation were carried out to study the influence of vegetation on the flows. In a half channel with two different densities of vegetation, the flow velocity, Reynolds stresses, and turbulence intensities were measured using an Acoustic Doppler Velocimeter (ADV). We obtained velocity profiles in the lateral direction, Reynolds stresses in the vertical direction, and the flow transition between the vegetated and non-vegetated zones in different flow regimes. The results show that the streamwise velocity in the vegetated zone with higher density is almost entirely blocked. Reynolds stress distribution distinguishes with two different regions: inside and above the vegetation canopies. The turbulence intensities increase with increasing Reynolds number. The coherent vortices dominate the vertical transport of momentum and are advected clockwise between the vegetated zone and non-vegetated zone by secondary currents (a relatively minor flow superimposed on the primary flow, with significantly different speed and direction), generated by the anisotropy of the turbulence.

  10. Flow structure on a rotating plate

    Ozen, C.A.; Rockwell, D. [Lehigh University, Department of Mechanical Engineering and Mechanics, Bethlehem, PA (United States)


    The flow structure on a rotating plate of low aspect ratio is characterized well after the onset of motion, such that transient effects are not significant, and only centripetal and Coriolis accelerations are present. Patterns of vorticity, velocity contours, and streamline topology are determined via quantitative imaging, in order to characterize the leading-edge vortex in relation to the overall flow structure. A stable leading-edge vortex is maintained over effective angles of attack from 30 to 75 , and at each angle of attack, its sectional structure at midspan is relatively insensitive to Reynolds number over the range from 3,600 to 14,500. The streamline topology, vorticity distribution, and circulation of the leading-edge vortex are determined as a function of angle of attack, and related to the velocity field oriented toward, and extending along, the leeward surface of the plate. The structure of the leading-edge vortex is classified into basic regimes along the span of the plate. Images of these regimes are complemented by patterns on crossflow planes, which indicate the influence of root and tip swirl, and spanwise flow along the leeward surface of the plate. Comparison with the equivalent of the purely translating plate, which does not induce the foregoing flow structure, further clarifies the effects of rotation. (orig.)

  11. Flow Structure in a Bedrock Canyon (Invited)

    Venditti, J. G.; Rennie, C. D.; Church, M. A.; Bomhof, J.; Lin, M.


    Bedrock canyon incision is widely recognized as setting the pace of landscape evolution. A variety of models link flow and sediment transport processes to the bedrock canyon incision rate. The model components that represent sediment transport processes are quite well developed in some models. In contrast, the model components that represent fluid flow remain rudimentary. Part of the reason is that there have been relatively few observations of flow structure in a bedrock canyon. Here, we present observations of flow obtained using an array of three acoustic Doppler current profilers during a 524 km long continuous centerline traverse of the Fraser River, British Columbia, Canada as it passes through a series of bedrock canyons. Through this portion of the river, the channel alternates between gravel-bedded reaches that are deeply incised into semi-consolidated glacial deposits and solid bedrock-bound reaches. We present observations of flow through 41 bedrock bound reaches of the river, derived from our centerline traverses and more detailed three-dimensional mapping of the flow structure in 2 canyons. Our observations suggest that flow in the most well-defined canyons (deep, laterally constrained, completely bedrock bound) is far more complex than that in a simple prismatic channel. As flow enters the canyon, a high velocity core plunges from the surface to the bed, causing a velocity inversion (high velocities at the bed and low velocities at the surface). This plunging flow then upwells along the canyon wall, resulting in a three-dimensional flow with counter-rotating, along-stream eddies that diverge near the bed. We observe centerline ridges along the canyon floors that result from the divergence and large-scale surface boils caused by the upwelling. This flow structure causes deep scour in the bedrock channel floor, and ensures the base of the canyon walls are swept of debris that otherwise may be deposited due to lower shear stresses abutting the walls. The

  12. Structure of Flow in a Bedrock Canyon

    Venditti, J. G.; Rennie, C. D.; Church, M. A.; Bomhof, J.; Lin, M.


    Bedrock canyon incision is widely recognized as setting the pace of landscape evolution. A variety of models link flow and sediment transport processes to the bedrock canyon incision rate. The model components that represent sediment transport processes are quite well developed in some models. In contrast, the model components that represent fluid flow remain rudimentary. Part of the reason is that there have been relatively few observations of flow structure in a bedrock canyon. Here, we present observations of flow obtained using an array of three acoustic Doppler current profilers during a 524 km long continuous centerline traverse of the Fraser River, British Columbia, Canada as it passes through a series of bedrock canyons. Through this portion of the river, the channel alternates between gravel-bedded reaches that are deeply incised into semi-consolidated glacial deposits and solid bedrock-bound reaches. We present observations of flow through 41 bedrock bound reaches of the river, derived from our centerline traverses and more detailed three-dimensional mapping of the flow structure in 2 canyons. Our observations suggest that flow in the most well-defined canyons (deep, laterally constrained, completely bedrock bound) is far more complex than that in a simple prismatic channel. As flow enters the canyon, a high velocity core plunges from the surface to the bed, causing a velocity inversion (high velocities at the bed and low velocities at the surface). This plunging flow then upwells along the canyon wall, resulting in a three-dimensional flow with counter-rotating, along-stream eddies that diverge near the bed. We observe centerline ridges along the canyon floors that result from the divergence and large-scale surface boils caused by the upwelling. This flow structure causes deep scour in the bedrock channel floor, and ensures the base of the canyon walls are swept of debris that otherwise may be deposited due to lower shear stresses abutting the walls. The

  13. Power Flow and Structure-Borne Noise

    Wachulec, Marcin

    The method of power flow analysis within a structure depends on the frequency considered. For the low frequencies the standard Finite Element Method (FEM) can be used efficiently. In the high frequencies the Statistical Energy Analysis (SEA) proved its usefulness. The distinction between low and ...... in plane and out of plane of the plate....

  14. Regional cerebral blood flow abnormalities in patients with primary hyperparathyroidism

    Cermik, Tevfik F. [Hospital of the University of Trakya, Department of Nuclear Medicine, Edirne (Turkey); Trakya Universitesi Hastanesi, Nukleer Tip Anabilim Dali, Gullapoglu Yerleskesi, Edirne (Turkey); Kaya, Meryem; Bedel, Deniz; Berkarda, Sakir; Yigitbasi, Oemer N. [Hospital of the University of Trakya, Department of Nuclear Medicine, Edirne (Turkey); Ugur-Altun, Betuel [Hospital of the University of Trakya, Department of Internal Medicine, Division of Endocrinology, Edirne (Turkey)


    We assessed the alterations in regional cerebral blood flow (rCBF) in patients with primary hyperparathyroidism (PHP) before parathyroidectomy by semiquantitative analysis of brain single photon emission computed tomography (SPECT) images. Included in this prospective study were 14 patients (mean age 47.6 {+-} 10.4 years; 3 male, 11 female) and 10 control subjects (mean age 36.0 {+-} 8.5 years, 6 male, 4 female) were SPECT imaging was performed using a dual-headed gamma camera 60-90 min after intravenous administration of 925 MBq Tc-99m HMPAO. The corticocerebellar rCBF ratios were calculated from 52 brain areas and reference lower values (RLVs) were calculated from the rCBF ratios of control subjects. The regional ratios that were below the corresponding RLV were considered abnormal (hypoperfused). Hypoperfusion was shown in 171 out of 728 regions (23%) and there was a significant correlation between serum calcium, PTH levels and the sum of hypoperfused regions in the patient group (R = 0.75 and P = 0.001, and R = 0.75, P = 0.001, respectively). Significantly reduced rCBF were found in the following cortical regions: bilateral cingulate cortex, superior and inferior frontal cortex, anterior temporal cortex, precentral gyrus, postcentral gyrus and parietal cortex, and right posterior temporal cortex. Our results indicate that alterations in rCBF in patients with PHP can be demonstrated with brain SPECT. The correlation between serum calcium, PTH levels and the sum of hypoperfused regions indicates that there may be a strong relationship between rCBF abnormalities and increased levels of serum calcium and PTH. In addition, the degree of rCBF abnormalities could be determined by brain SPECT in PHP patients with or without psychiatric symptoms. (orig.)

  15. Flow Structure Associated with Hemodialysis Catheters

    Foust, Jason


    Insertion of a hemodialysis catheter into the superior vena cava (SVC) gives rise to complex flow patterns, which arise from the simultaneous injection and extraction of blood through different holes (ports) of the catheter. Techniques of high-image-density particle image velocimetry are employed in a scaled-up water facility. This approach allows characterization of both the instantaneous and time-averaged flow structure due to generic classes of side hole geometries. The trajectory of the injection jet is related to the ratio of the initial jet velocity to the mainstream velocity through the SVC, and to the type of distortion of the jet cross-section. Furthermore, the mean and fluctuating velocity and vorticity fields are determined. Significant turbulent stresses develop rapidly in the injection jet, which can impinge upon the wall of the simulated SVC. Immediately downstream of the injection hole, a recirculation cell of low velocity exists adjacent to the catheter surface. These and other representations of the flow structure are first evaluated for a steady throughflow, then for the case of a pulsatile waveform in the SVC, which matches that of a normal adult.

  16. Role of flow cytometry in the diagnosis and monitoring of primary immunodeficiency disease.

    O'gorman, Maurice R G


    This presentation is organized according to the recent classification of primary immunodeficiencies published by the International Union of Immunological Societies Primary Immunodeficiency meeting. The diseases have been classified into eight groups. After each list, individual diseases that are amenable to assessment by flow cytometry are reviewed with a brief clinical description and a discussion of the appropriate flow cytometry application.

  17. Flow structure in front of the broad-crested weir

    Zachoval Zbyněk


    Full Text Available The paper deals with research focused on description of flow structure in front of broad-crested weir. Based on experimental measurement, the flow structure in front of the weir (the recirculation zone of flow and tornado vortices and flow structure on the weir crest has been described. The determined flow character has been simulated using numerical model and based on comparing results the suitable model of turbulence has been recommended.

  18. Structure Property Correlations in Primary Explosives


    is to the elements; therefore, the heat of detonation (an indicator of sensitivity) is simply the heat of formation for the metal azides, AgN - of compounds. Furthermore, the heat of detonation is not the sole criterion for usefulness as a primary. TNT has a higher heat of detonation than

  19. The CFRP primary structure of the MIRI instrument onboard the James Webb Space Telescope

    Jessen, Niels Christian; Nørgaard-Nielsen, Hans Ulrik; Schroll, J


    The design of the Primary Structure of the Mid Infra-Red Instrument (MIRI) onboard the NASA/ESA James Webb Space Telescope will be presented. The main design driver is the energy flow from the 35 K "hot" satellite interface to the 7 K "cold" MIRI interface. Carbon fibre reinforced plastic (CFRP...

  20. Resistive interchange modes and plasma flow structures

    Paccagnella, Roberto


    Interchange modes are ubiquitous in magnetic confinement systems and are likely to determine or influence their transport properties. For example a good agreement between theory predictions for linear interchange modes and experimental results has been found recently in a Reverse Field Pinch device. In this work a set of magneto-hydro-dynamic (MHD) equations that describe the dynamical evolution for the pressure driven interchange modes in a magnetic confinement system are studied. Global and local solutions relevant for tokamaks and Reversed Field Pinches (RFPs) configurations are considered. The emphasis is especially in the characterization of the plasma flow structures associated with the dominant modes.

  1. Topological Structures in Rotating Stratified Flows

    Redondo, J. M.; Carrillo, A.; Perez, E.


    Detailled 2D Particle traking and PIV visualizations performed on a series of large scale laboratory experiments at the Coriolis Platform of the SINTEF in Trondheim have revealed several resonances which scale on the Strouhal, the Rossby and the Richardson numbers. More than 100 experiments spanned a wide range of Rossby Deformation Radii and the topological structures (Parabolic /Eliptic /Hyperbolic) of the quasi-balanced stratified-rotating flows were studied when stirring (akin to coastal mixing) occured at a side of the tank. The strong asymetry favored by the total vorticity produces a wealth of mixing patterns.

  2. A beam-membrane structure micromachined differential pressure flow sensor.

    Chen, P; Zhao, Y L; Tian, B; Li, C; Li, Y Y


    A beam-membrane structure micromachined flow sensor is designed, depending on the principle of differential pressure caused by the mass flow, which is directly proportional to the square flow rate. The FSI (fluid structure interaction) characteristics of the differential pressure flow sensor are investigated via numerical analysis and analog simulation. The working mechanism of the flow sensor is analyzed depending on the FSI results. Then, the flow sensor is fabricated and calibrated. The calibration results show that the beam-membrane structure differential pressure flow sensor achieves ideal static characteristics and works well in the practical applications.


    谢锡麟; 麻伟巍; 周慧良


    The dynamical behaviors of coherent structures in countercurrent axisymmetric shear flows are experimentally studied. The forward velocity U1 and the velocity ratio R = (U1 - U2)/(U1 +U2), where U2 denotes the suction velocity, are considered as the control parameters. Two kinds of vortex structures, i.e., axisymmetric and helical structures, were discovered with respect to different regimes in the R versus U1 diagram. In the case of U1 ranging from 3 to 20 m/s and R from 1 to 3, the axisymmetric structures play an important role. Based on the dynamical behaviors of axisymmetric structures, a critical forward velocity Ucr1 = 6.8 m/s was defined, subsequently, the subcritical velocity regime: U1 > Ucr1 and the supercritical velocity regime: U1 < Ucr1. In the subcritical velocity regime,the flow system contains shear layer self-excited oscillations in a certain range of the velocity ratio with respect to any forward velocity. In the supercritical velocity regime, the effect of the velocity ratio could be explained by the relative movement and the spatial evolution of the axisymmetric structure undergoes the following stages: (1) Kelvin-Helmholtz instability leading to vortex rolling up, (2) first time vortex agglomeration, (3) jet column self-excited oscillation, (4) shear layer self-excited oscillation,(5) "ordered tearing", (6) turbulence in the case of U1 < 4 m/s (the "ordered tearing" does not exist when U1 > 4m/s), correspondingly, the spatial evolution of the temporal asymptotic behavior of a dynamical system can be described as follows: (1) Hopf bifurcation, (2) subharmonic bifurcation, (3)reversed superharmonic bifurcation, (4) superharmonic bifurcation, (5) chaos ("weak turbulence") in the case of U1 < 4 m/s (superharmonic bifurcation does not exist when U1 > 4 m/s). The proposed new terms, superharmonic and reversed superharmonic bifurcations, are characterized of the frequency doubling rather than the period doubling. A kind of unfamiliar

  4. The european primary care monitor: structure, process and outcome indicators

    Wilson Andrew


    Full Text Available Abstract Background Scientific research has provided evidence on benefits of well developed primary care systems. The relevance of some of this research for the European situation is limited. There is currently a lack of up to date comprehensive and comparable information on variation in development of primary care, and a lack of knowledge of structures and strategies conducive to strengthening primary care in Europe. The EC funded project Primary Health Care Activity Monitor for Europe (PHAMEU aims to fill this gap by developing a Primary Care Monitoring System (PC Monitor for application in 31 European countries. This article describes the development of the indicators of the PC Monitor, which will make it possible to create an alternative model for holistic analyses of primary care. Methods A systematic review of the primary care literature published between 2003 and July 2008 was carried out. This resulted in an overview of: (1 the dimensions of primary care and their relevance to outcomes at (primary health system level; (2 essential features per dimension; (3 applied indicators to measure the features of primary care dimensions. The indicators were evaluated by the project team against criteria of relevance, precision, flexibility, and discriminating power. The resulting indicator set was evaluated on its suitability for Europe-wide comparison of primary care systems by a panel of primary care experts from various European countries (representing a variety of primary care systems. Results The developed PC Monitor approaches primary care in Europe as a multidimensional concept. It describes the key dimensions of primary care systems at three levels: structure, process, and outcome level. On structure level, it includes indicators for governance, economic conditions, and workforce development. On process level, indicators describe access, comprehensiveness, continuity, and coordination of primary care services. On outcome level, indicators

  5. Basic flow structure in saccular aneurysms: a flow visualization study.

    Steiger, H J; Poll, A; Liepsch, D; Reulen, H J


    Basic flow patterns were investigated in a set of glass aneurysm models by means of flow visualization methods. Dye injection and streaming double refraction were used to visualize flow. The circulation inside lateral aneurysms arising at a 90 degree angle from a straight parent conduit could not be visualized by the dye-injection technique but could be demonstrated by streaming double refraction. The inflow was seen to arise from the downstream lip of the orifice and to project to the dome of the aneurysm. Backflow to the parent conduit took place along the walls of the aneurysm. In aneurysms located at bifurcations, flow characteristics depended on the geometry of the bifurcation and the flow ratio between the branches. Relatively little intra-aneurysmal flow was demonstrated in side branch-related aneurysms arising distal to an asymmetric 90 degrees bifurcation of the type encountered at the junction of the internal carotid and posterior communicating arteries. Stagnation of flow at the neck and little intra-aneurysmal circulation were found with terminal aneurysms of the basilar bifurcation type if the outflow through the branches was symmetric. With asymmetric outflow, however, or if the axis of the aneurysm did not coincide with that of the afferent vessel, an active rotation developed in these aneurysms. The size of the aneurysm had no influence on the basic pattern of intra-aneurysmal circulation. The use of pulsatile perfusion did not significantly alter the basic flow patterns observed with steady flow. Locally disturbed laminar flow was observed in certain models at physiological Reynold's numbers, but there were no signs of fully developed turbulence.

  6. Flow-induced vibrations of circular cylindrical structures. [LMFBR

    Chen, S.


    The problems of flow-induced vibrations of circular cylindrical structures are reviewed. First, the general method of analysis and classification of structural responses are presented. Then, the presentation is broken up along the lines with stationary fluid, parallel flow, and cross flow. Finally, design considerations and future research needs are pointed out. 234 references.

  7. Short- and Long- Time Transport Structures in a Three Dimensional Time Dependent Flow

    Chabreyrie, Rodolphe


    Lagrangian transport structures for three-dimensional and time-dependent fluid flows are of great interest in numerous applications, particularly for geophysical or oceanic flows. In such flows, chaotic transport and mixing can play important environmental and ecological roles, for examples in pollution spills or plankton migration. In such flows, where simulations or observations are typically available only over a short time, understanding the difference between short-time and long-time transport structures is critical. In this paper, we use a set of classical (i.e. Poincar\\'e section, Lyapunov exponent) and alternative (i.e. finite time Lyapunov exponent, Lagrangian coherent structures) tools from dynamical systems theory that analyze chaotic transport both qualitatively and quantitatively. With this set of tools we are able to reveal, identify and highlight differences between short- and long-time transport structures inside a flow composed of a primary horizontal contra-rotating vortex chain, small later...

  8. Structure of group invariants of a quasiperiodic flow

    Lennard F. Bakker


    Full Text Available It is shown that the multiplier representation of the generalized symmetry group of a quasiperiodic flow induces a semidirect product structure on certain group invariants (including the generalized symmetry group of the flow's smooth conjugacy class.

  9. Fine-Structured Plasma Flows in Prominences

    Panasenco, O.; Velli, M.; Landi, S.


    Plasmas in prominences (filaments against the disk) exhibit a very wide spectrum of different kind of motions. Here we analyze the plasma motions inside prominences observed by Hinode/SOT during 2006-2007 with focus on two spectacular examples from 25 April 2007 in Halpha line and 30 November 2006 in CaH line and then carry out some simulations of the possible dynamics. Most filaments are composed of fine threads of similar dimensions rooted in the chromosphere/photosphere. Recent observations of counter-streaming motions together with oscillations along the threads provide strong evidence that the threads are field aligned. To more correctly interpret the nature of observed downward flows of dense and cool plasma as well as the upward dark flows of less dense plasma, we take into account the geometry of the prominence structures and the viewing angle. The dark upflows exhibit turbulent patterns such as vortex formation and shedding that are consistent with the motions predicted by instabilities of the interchange type. Sometimes an appearance of dark motions is generated by dark voids opened in the prominence sheet after initiation of nearby downflow streams, implying mass drainage in the downflows. Based on 304 A observations, there is more filament mass in prominences than is visible in either the Halpha or CaH lines. The source of the downward moving plasma may be located either higher above the visible upper edge of the prominence or on the far end of the prominence spine. The bright downward motions of the more cool and dense plasma may be partly due to the counter-streaming motion along the magnetic fields lines and also to the presence of Rayleigh-Taylor type or ballooning/interchange instabilities in the upper regions of the prominence. Transverse motions of filament threads caused by magnetic instabilities constantly provide the conditions for reconnection in the low part of the corona and the chromosphere. We suggest that the combination of flows along

  10. Flow Structures Around Micro-bubbles During Subcooled Nucleate Boiling

    WANG Hao; PENG Xiao-Feng; David M. Christopher; WANG Bu-Xuan


    The flow structures were investigated around micro bubbles on extremely thin wires during subcooled nucleate boiling. Jet flows emanating from the bubbles were observed visually with the fluid field measurement using high-speed photography and a PIV system. The jet flows induced a strong pumping effect around a bubble. The multi-jet structure was further observed experimentally, indicating the evolution of flow structure around micro bubbles. Numerical simulations explore that the jet flows were induced by a strong Marangoni effect due to high temperature gradients near the wire. The bubble interface with multi-jet structure has abnormal temperature distribution such that the coolest parts were observed at two sides of a bubble extending into the subcooled bulk liquid rather than at the top. Evaporation and condensation on the bubble interface play important roles not only in controlling the intensity of the jet flow, but also in bringing out the multi-jet structure.

  11. Studying geometric structures in meso-scale flows

    Christos H. Halios


    Full Text Available Geometric shapes of coherent structures such as ramp or cliff like signals, step changes and waves, are commonly observed in meteorological temporal series and dominate the turbulent energy and mass exchange between the atmospheric surface layer and the layers above, and also relate with low-dimensional chaotic systems. In this work a simple linear technique to extract geometrical shapes has been applied at a dataset which was obtained at a location experiencing a number of different mesoscale modes. It was found that the temperature field appears much better organized than the wind field, and that cliff-ramp structures are dominant in the temperature time series. The occurrence of structural shapes was related with the dominant flow patterns and the status of the flow field. Temperature positive cliff-ramps and ramp-cliffs appear mainly during night time and under weak flow field, while temperature step and sine structures do not show a clear preference for the period of day, flow or temperature pattern. Uniformly stable, weak flow conditions dominate across all the wind speed structures. A detailed analysis of the flow field during two case studies revealed that structural shapes might be part of larger flow structures, such as a sea-breeze front or down-slope winds. During stagnant conditions structural shapes that were associated with deceleration of the flow were observed, whilst during ventilation conditions shapes related with the acceleration of the flow.

  12. The primary structure of Vipera ammodytes venom trypsin inhibitor I.

    Ritonja, A; Meloun, B; Gubensek, F


    The primary structure of Vipera ammodytes venom trypsin inhibitor I consists of 61 amino acid residues [sequence in text]. The N-terminal group of the inhibitor is pyrrolidonecarboxylic acid. The sequential data were obtained by analysis of peptides isolated from tryptic and chymotryptic digests and by analysis of peptides derived from the hydrolysis of the aspartyl-prolyl bond of the carboxymethylated inhibitor. The primary structure of trypsin inhibitor I presented shows approximately 80% sequence homology with chymotrypsin inhibitor isolated from the venom of the same snake, and nearly 50% homology with bovine basic pancreatic trypsin inhibitor. It belongs to the Kunitz-pancreatic trypsin inhibitor family of inhibitors.

  13. The Use of Energy in Malaysia: Tracing Energy Flows from Primary Source to End Use

    Chinhao Chong


    Full Text Available Malaysia is a rapidly developing country in Southeast Asia that aims to achieve high-income country status by 2020; its economic growth is highly dependent on its abundant energy resources, especially natural gas and crude oil. In this paper, a complete picture of Malaysia’s energy use from primary source to end use is presented by mapping a Sankey diagram of Malaysia’s energy flows, together with ongoing trends analysis of the main factors influencing the energy flows. The results indicate that Malaysia’s energy use depends heavily on fossil fuels, including oil, gas and coal. In the past 30 years, Malaysia has successfully diversified its energy structure by introducing more natural gas and coal into its power generation. To sustainably feed the rapidly growing energy demand in end-use sectors with the challenge of global climate change, Malaysia must pay more attention to the development of renewable energy, green technology and energy conservation in the future.

  14. Unsteady Flow Structure on Low Aspect Ratio Wings


    following, the flow structure is addressed in further detail for excitation at fe = fo/2. Figures A4a through A4c compare the flow structure on the...shown in Figure A4a , irrespective of the spanwise location , the effect of excitation is to substantially decrease the streamwise extent of the high

  15. Chaotic Flows Correlation effects and coherent structures

    Bakunin, Oleg G


    The book introduces readers to and summarizes the current ideas and theories about the basic mechanisms for transport in chaotic flows. Typically no single paradigmatic approach exists as this topic is relevant for fields as diverse as plasma physics, geophysical flows and various branches of engineering. Accordingly, the dispersion of matter in chaotic or turbulent flows is analyzed from different perspectives. Partly based on lecture courses given by the author, this book addresses both graduate students and researchers in search of a high-level but approachable and broad introduction to the topic.

  16. Elicitation of Specific Syntactic Structures in Primary Progressive Aphasia

    DeLeon, Jessica; Gesierich, Benno; Besbris, Max; Ogar, Jennifer; Henry, Maya L.; Miller, Bruce L.; Gorno-Tempini, Maria Luisa; Wilson, Stephen M.


    Many patients with primary progressive aphasia (PPA) are impaired in syntactic production. Because most previous studies of expressive syntax in PPA have relied on quantitative analysis of connected speech samples, which is a relatively unconstrained task, it is not well understood which specific syntactic structures are most challenging for these…

  17. Structural and functional lung disease in primary ciliary dyskinesia

    F. Santamaria (Francesca); S. Montella (Silvia); H.A.W.M. Tiddens (Harm); G. Guidi (Guido); V. Casotti (Valeria); M. Maglione (Marco); P.A. de Jong (Pim)


    textabstractBackground: High-resolution CT (HRCT) scan data on primary ciliary dyskinesia (PCD) related lung disease are scarce. Study objectives: We evaluated the lung disease in children and adults with PCD by a modified Brody composite HRCT scan score to assess the prevalence of the structural ab

  18. Surface Structure Enhanced Microchannel Flow Boiling

    Zhu, Yangying; Antao, Dion Savio; Chu, Kuang-Han; Chen, Siyu; Hendricks, Terry J.; Zhang, Tiejun; Wang, Evelyn N.


    We investigated the role of surface microstructures in two-phase microchannels on suppressing flow instabilities and enhancing heat transfer. We designed and fabricated microchannels with well-defined silicon micropillar arrays on the bottom heated microchannel wall to promote capillary flow for thin film evaporation while facilitating nucleation only from the sidewalls. Our experimental results show significantly reduced temperature and pressure drop fluctuation especially at high heat fluxe...

  19. Flow coherent structures and frequency signature: application of the dynamic modes decomposition to open cavity flow

    Lusseyran, F; Gueniat, F; Basley, J; Douay, C L; Pastur, L R; Faure, T M [LIMSI-CNRS BP 133, F-91403 Orsay Cedex (France); Schmid, P J [LadHyX, Ecole Polytechnique, F-91128 Palaiseau (France)


    The dynamic dimension of an impinging flow may be significantly reduced by its boundary conditions and self-sustained oscillations they induce. The spectral signature is associated with remarkable spatial coherent structures. Dynamic modes decomposition (DMD) makes it possible to directly extract the dynamical properties of a non-linearly saturated flow. We apply DMD to highlight the spectral contribution of the longitudinal and transverse structures of an experimental open-cavity flow.

  20. The primary cilium as sensor of fluid flow: new building blocks to the model

    Prætorius, Helle


    The primary cilium is an extraordinary organelle. For many years, it had the full attention of only a few dedicated scientists fascinated by its uniqueness. Unexpectedly, after decades of obscurity, it has moved very quickly into the limelight with the increasing evidence of its central role...... in the many genetic variations that lead to what are now known as ciliopathies. These studies implicated unique biological functions of the primary cilium, which are not completely straightforward. In parallel, and initially completely unrelated to the ciliopathies, the primary cilium was characterized...... functionally as an organelle that makes cells more susceptible to changes in fluid flow. Thus the primary cilium was suggested to function as a flow-sensing device. This characterization has been substantiated for many epithelial cell types over the years. Nevertheless, part of the central mechanism of signal...

  1. Vibration test on KMRR reactor structure and primary cooling system piping

    Chung, Seung Hoh; Kim, Tae Ryong; Park, Jin Hoh; Park, Jin Suk; Ryoo, Jung Soo [Korea Atomic Energy Research Institute, Taejon (Korea, Republic of)


    Most equipments, piping systems and reactor structures in nuclear power plants are subjected to flow induced vibration due to high temperature and high pressure coolant flowing inside or outside of the equipments, systems and structures. Because the flow induced vibration sometimes causes significant damage to reactor structures and piping systems, it is important and necessary to evaluate the vibration effect on them and to prove their structural integrity. Korea Multipurpose Research Reactor (KMRR) being constructed by KAERI is 30 MWt pool type research reactor. Since its main structures and piping systems were designed and manufactured in accordance with the standards and guidelines for commercial nuclear power plant, it was decided to evaluate their vibratory response in accordance with the standards and guidelines for commercial NPP. The objective of this vibration test is the assessment of vibration levels of KMRR reactor structure and primary cooling piping system for their structural integrity under the steady-state or transient operating condition. 38 figs, 14 tabs, 2 refs. (Author).

  2. The Flow Structure on the WWW

    Wu, Lingfei


    Background: Viewing the World Wide Web as a river network in which web pages are the confluences, hyperlinks are the channels, and clickstreams showing the navigation of users from one website to another are the water flows. In this way we can model the flow of human attention in a weighted, direct network comparable to transportation networks in organisms or ecosystems. Methodology: We construct a network comprising of 980 websites and 12,008 clickstreams with the publicly accessible data on The total traffic to these websites accounts for 97% of the global Internet traffic. Three quantities of interest are defined on the network, including connectance k, characteristic flow length l, and recycling rate. To study the size-variant properties of the clickstream, we detect six communities and observe how the three quantities change with community size. Conclusions: The clickstream network can be divided into language-based website communities, across which a scaling relationship in the clickstrea...

  3. Geometric structure of pseudo-plane quadratic flows

    Sun, Che


    Quadratic flows have the unique property of uniform strain and are commonly used in turbulence modeling and hydrodynamic analysis. While previous applications focused on two-dimensional homogeneous fluid, this study examines the geometric structure of three-dimensional quadratic flows in stratified fluid by solving a steady-state pseudo-plane flow model. The complete set of exact solutions reveals that steady quadratic flows have an invariant conic type in the non-rotating frame and a non-rotatory vertical structure in the rotating frame. Three baroclinic solutions with vertically non-aligned formulation disprove an earlier conjecture. All elliptic and hyperbolic solutions, except for the inertial ones, exhibit vertical concentricity. The rich geometry of quadratic flows stands in contrast to the depleted geometry of high-degree polynomial flows. A paradox in the steady solutions of shallow-water reduced-gravity models is also explained.

  4. Primary oxidation variation and distribution of uranium and thorium in a lava flow.

    Watkins, N D; Holmes, C W; Haggerty, S E


    An Icelandic basalt lava flow has a systematic oxidation variation, formed during the initial cooling, with a resultant maximum oxidation just below the center of the lava. The ratio of thorium to uranium shows a clear dependence on this primary oxidation variation. Between-lava comparisons of thorium and uranium may be critically dependent on the position of the samples in each lava.

  5. Large-eddy simulation of cavitating nozzle flow and primary jet break-up

    Örley, F.; Trummler, T.; Hickel, S.; Mihatsch, M.S.; Schmidt, S.J.; Adams, N.A.


    We employ a barotropic two-phase/two-fluid model to study the primary break-up of cavitating liquid jets emanating from a rectangular nozzle, which resembles a high aspect-ratio slot flow. All components (i.e., gas, liquid, and vapor) are represented by a homogeneous mixture approach. The cavitating

  6. Flow Structure and Turbulence in Wind Farms

    Stevens, Richard J. A. M.; Meneveau, Charles


    Similar to other renewable energy sources, wind energy is characterized by a low power density. Hence, for wind energy to make considerable contributions to the world's overall energy supply, large wind farms (on- and offshore) consisting of arrays of ever larger wind turbines are being envisioned and built. From a fluid mechanics perspective, wind farms encompass turbulent flow phenomena occurring at many spatial and temporal scales. Of particular interest to understanding mean power extraction and fluctuations in wind farms are the scales ranging from 1 to 10 m that comprise the wakes behind individual wind turbines, to motions reaching 100 m to kilometers in scale, inherently associated with the atmospheric boundary layer. In this review, we summarize current understanding of these flow phenomena (particularly mean and second-order statistics) through field studies, wind tunnel experiments, large-eddy simulations, and analytical modeling, emphasizing the most relevant features for wind farm design and operation.

  7. Biophysics and biofluid dynamics of primary cilia: evidence for and against the flow-sensing function.

    Nag, Subhra; Resnick, Andrew


    Primary cilia have been called "the forgotten organelle" for over 20 yr. As cilia now have their own journal and several books devoted to their study, perhaps it is time to reconsider the moniker "forgotten organelle." In fact, during the drafting of this review, 12 relevant publications have been issued; we therefore apologize in advance for any relevant work we inadvertently omitted. What purpose is yet another ciliary review? The primary goal of this review is to specifically examine the evidence for and against the hypothesized flow-sensing function of primary cilia expressed by differentiated epithelia within a kidney tubule, bringing together differing disciplines and their respective conceptual and experimental approaches. We will show that understanding the biophysics/biomechanics of primary cilia provides essential information for understanding any potential role of ciliary function in disease. We will summarize experimental and mathematical models used to characterize renal fluid flow and incident force on primary cilia and to characterize the mechanical response of cilia to an externally applied force and discuss possible ciliary-mediated cell signaling pathways triggered by flow. Throughout, we stress the importance of separating the effects of fluid shear and stretch from the action of hydrodynamic drag. Copyright © 2017 the American Physiological Society.

  8. The primary cilium as sensor of fluid flow: new building blocks to the model

    Prætorius, Helle


    functionally as an organelle that makes cells more susceptible to changes in fluid flow. Thus the primary cilium was suggested to function as a flow-sensing device. This characterization has been substantiated for many epithelial cell types over the years. Nevertheless, part of the central mechanism of signal......The primary cilium is an extraordinary organelle. For many years, it had the full attention of only a few dedicated scientists fascinated by its uniqueness. Unexpectedly, after decades of obscurity, it has moved very quickly into the limelight with the increasing evidence of its central role...... transduction has not been explained, largely because of the substantial technical challenges of working with this delicate organelle. The current review considers the recent advances that allow us to fill some of the holes in the model of signal transduction in cilium-mediated responses to fluid flow...

  9. Factor structure of functional state of primary school age children

    Davidenko O.V.


    Full Text Available The examination of primary school children to determine the ranking of significant factors that determine the structure of their functional state depending on the level of physical health. It is shown that the main factor in the structure of the functional state of younger schoolchildren in low-and lower-middle level of physical fitness is selected morpho-functional status, which characterizes the functions of the body at rest. For children with average or above average level of physical fitness is a leading factor in physical fitness of schoolchildren.

  10. Structural support bracket for gas flow path



    A structural support system is provided in a can annular gas turbine engine having an arrangement including a plurality of integrated exit pieces (IEPs) forming an annular chamber for delivering gases from a plurality of combustors to a first row of turbine blades. A bracket structure is connected between an IEP and an inner support structure on the engine. The bracket structure includes an axial bracket member attached to an IEP and extending axially in a forward direction. A transverse bracket member has an end attached to the inner support structure and extends circumferentially to a connection with a forward end of the axial bracket member. The transverse bracket member provides a fixed radial position for the forward end of the axial bracket member and is flexible in the axial direction to permit axial movement of the axial bracket member.

  11. Nasal High-Flow Therapy for Primary Respiratory Support in Preterm Infants.

    Roberts, Calum T; Owen, Louise S; Manley, Brett J; Frøisland, Dag H; Donath, Susan M; Dalziel, Kim M; Pritchard, Margo A; Cartwright, David W; Collins, Clare L; Malhotra, Atul; Davis, Peter G


    Background Treatment with nasal high-flow therapy has efficacy similar to that of nasal continuous positive airway pressure (CPAP) when used as postextubation support in neonates. The efficacy of high-flow therapy as the primary means of respiratory support for preterm infants with respiratory distress has not been proved. Methods In this international, multicenter, randomized, noninferiority trial, we assigned 564 preterm infants (gestational age, ≥28 weeks 0 days) with early respiratory distress who had not received surfactant replacement to treatment with either nasal high-flow therapy or nasal CPAP. The primary outcome was treatment failure within 72 hours after randomization. Noninferiority was determined by calculating the absolute difference in the risk of the primary outcome; the chosen margin of noninferiority was 10 percentage points. Infants in whom high-flow therapy failed could receive rescue CPAP; infants in whom CPAP failed were intubated and mechanically ventilated. Results Trial recruitment stopped early at the recommendation of the independent data and safety monitoring committee because of a significant difference in the primary outcome between treatment groups. Treatment failure occurred in 71 of 278 infants (25.5%) in the high-flow group and in 38 of 286 infants (13.3%) in the CPAP group (risk difference, 12.3 percentage points; 95% confidence interval [CI], 5.8 to 18.7; Prespiratory distress, high-flow therapy resulted in a significantly higher rate of treatment failure than did CPAP. (Funded by the National Health and Medical Research Council and others; Australian New Zealand Clinical Trials Registry number, ACTRN12613000303741 .).

  12. Multi-cellular 3D human primary liver cell culture elevates metabolic activity under fluidic flow.

    Esch, Mandy B; Prot, Jean-Matthieu; Wang, Ying I; Miller, Paula; Llamas-Vidales, Jose Ricardo; Naughton, Brian A; Applegate, Dawn R; Shuler, Michael L


    We have developed a low-cost liver cell culture device that creates fluidic flow over a 3D primary liver cell culture that consists of multiple liver cell types, including hepatocytes and non-parenchymal cells (fibroblasts, stellate cells, and Kupffer cells). We tested the performance of the cell culture under fluidic flow for 14 days, finding that hepatocytes produced albumin and urea at elevated levels compared to static cultures. Hepatocytes also responded with induction of P450 (CYP1A1 and CYP3A4) enzyme activity when challenged with P450 inducers, although we did not find significant differences between static and fluidic cultures. Non-parenchymal cells were similarly responsive, producing interleukin 8 (IL-8) when challenged with 10 μM bacterial lipoprotein (LPS). To create the fluidic flow in an inexpensive manner, we used a rocking platform that tilts the cell culture devices at angles between ±12°, resulting in a periodically changing hydrostatic pressure drop between reservoirs and the accompanying periodically changing fluidic flow (average flow rate of 650 μL min(-1), and a maximum shear stress of 0.64 dyne cm(-2)). The increase in metabolic activity is consistent with the hypothesis that, similar to unidirectional fluidic flow, primary liver cell cultures increase their metabolic activity in response to fluidic flow periodically changes direction. Since fluidic flow that changes direction periodically drastically changes the behavior of other cells types that are shear sensitive, our findings support the theory that the increase in hepatic metabolic activity associated with fluidic flow is either activated by mechanisms other than shear sensing (for example increased opportunities for gas and metabolite exchange), or that it follows a shear sensing mechanism that does not depend on the direction of shear. Our mode of device operation allows us to evaluate drugs under fluidic cell culture conditions and at low device manufacturing and operation

  13. Flow-Induced Vibration of Circular Cylindrical Structures

    Chen, Shoei-Sheng [Argonne National Lab. (ANL), Argonne, IL (United States). Components Technology Division


    Flow-induced vibration is a term to denote those phenomena associated with the response of structures placed in or conveying fluid flow. More specifically, the terra covers those cases in which an interaction develops between fluid-dynamic forces and the inertia, damping or elastic forces in the structures. The study of these phenomena draws on three disciplines: (1) structural mechanics, (2) mechanical vibration, and (3) fluid dynamics. The vibration of circular cylinders subject to flow has been known to man since ancient times; the vibration of a wire at its natural frequency in response to vortex shedding was known in ancient Greece as aeolian tones. But systematic studies of the problem were not made until a century ago when Strouhal established the relationship between vortex shedding frequency and flow velocity for a given cylinder diameter. The early research in this area has beer summarized by Zdravkovich (1985) and Goldstein (1965). Flow-induced structural vibration has been experienced in numerous fields, including the aerospace industry, power generation/transmission (turbine blades, heat exchanger tubes, nuclear reactor components), civil engineering (bridges, building, smoke stacks), and undersea technology. The problems have usually been encountered or created accidentally through improper design. In most cases, a structural or mechanical component, designed to meet specific objectives, develops problems when the undesired effects of flow field have not been accounted for in the design. When a flow-induced vibration problem is noted in the design stage, the engineer has different options to eliminate the detrimental vibration. Unfortunately, in many situations, the problems occur after the components are already in operation; the "fix" usually is very costly. Flow-induced vibration comprises complex and diverse phenomena; subcritical vibration of nuclear fuel assemblies, galloping of transmission lines, flutter of pipes conveying fluid, and whirling

  14. Beltrami flow structure in a diffuser. Quasi-cylindrical approximation

    González, Rafael; Sartarelli, Andrés Salvador; 10.4279/PIP.040002


    We determine the flow structure in an axisymmetric diffuser or expansion region connecting two cylindrical pipes when the inlet flow is a solid body rotation with a uniform axial flow of speeds Omega and U, respectively. A quasi-cylindrical approximation is made in order to solve the steady Euler equation, mainly the Bragg-Hawthorne equation. As in our previous work on the cylindrical region downstream [R Gonz\\'alez et al., Phys. Fluids 20, 24106 (2008); R. Gonz\\'alez et al., Phys. Fluids 22, 74102 (2010), R Gonz\\'alez et al., J. Phys.: Conf. Ser. 296, 012024 (2011)], the steady flow in the transition region shows a Beltrami flow structure. The Beltrami flow is defined as a field v_B that satisfies omega_B=nabla v_B= gamma v_B, with gamma = constant. We say that the flow has a Beltrami flow structure when it can be put in the form v = U e_z + Omega r e_theta + v_B, being U and Omega constants, i.e it is the superposition of a solid body rotation and translation with a Beltrami one. Therefore, those findings a...

  15. Dynamical structure of magnetized dissipative accretion flow around black holes

    Sarkar, Biplob


    We study the global structure of optically thin, advection dominated, magnetized accretion flow around black holes. We consider the magnetic field to be turbulent in nature and dominated by the toroidal component. With this, we obtain the complete set of accretion solutions for dissipative flows where bremsstrahlung process is regarded as the dominant cooling mechanism. We show that rotating magnetized accretion flow experiences virtual barrier around black hole due to centrifugal repulsion that can trigger the discontinuous transition of the flow variables in the form of shock waves. We examine the properties of the shock waves and find that the dynamics of the post-shock corona (PSC) is controlled by the flow parameters, namely viscosity, cooling rate and strength of the magnetic field, respectively. We separate the effective region of the parameter space for standing shock and observe that shock can form for wide range of flow parameters. We obtain the critical viscosity parameter that allows global accret...

  16. Flow acoustics in solid-fluid structures

    Willatzen, Morten; Mads, Mikhail Vladimirovich Deryabin


    along the x direction. In the first part of the paper, the governing set of differential equations are derived as well as the imposed boundary conditions. Solutions are provided using Hamilton's equations for the wavenumber vs. frequency as a function of the number and thickness of solid layers....... A wavenumber condition for an arbitrary set of consecutive solid and fluid layers, involving four propagating waves in each solid region, is obtained again using the monodromy matrix method. Case examples are finally discussed.......The governing two-dimensional equations of a heterogeneous material composed of a fluid (allowed to flow in the absence of acoustic excitations) and a crystalline piezoelectric cubic solid stacked one-dimensionally (along the z direction) are derived and special emphasis is given to the discussion...

  17. Visualizing the internal structure of subaqueous, high-concentration sediment-laden flows: implication of rheology to flow structure

    Perillo, M. M.; Buttles, J.; Mohrig, D. C.; Kane, I.; Pontén, A.; Brown, D.; Minton, B. W.


    Subaqueous sediment-laden flows are thought to be the main mechanism transporting sediments to the deep sea. Understanding the processes governing these flows is crucial to building predictive models of flow behaviour, sediment transport and deposition and is applicable to a wide range of disciplines. Physical modelling using a wide range of experimental facilities and measurement techniques has significantly advanced our understanding of these sediment-laden flows and their ability to erode, transport and deposit sediments. However, for the case of high-sediment concentration flows, measuring flow and depositional properties is still a challenge. Here, we present results from an acoustic reflection technique that allows for direct and noninvasive visualization of the internal structure of high concentration, clay-rich, sand-laden flows with a range of initial yield strengths (0-26 Pa). As the acoustic signal travels through the sediment-laden flow, it encounters zones of varying acoustic impedance that are due to temporal and spatial changes in sediment concentration, grain size and sorting, and flow mixing. The reflected signal is processed and interpreted using seismic techniques developed in exploration geophysics. The ultrasonic reflection data captured two distinct flow stages, an active stage and a post-depositional creeping stage. The clay-rich sand-laden flows showed stratification expressed by three clear vertical zones: (a) an upper relatively dilute turbulent zone, (b) a zone with high sediment concentration and significantly reduced mixing and (c) an aggrading bed of static grains.

  18. Influence of chemistry on steam generator primary-to-secondary stabilized low leak flow rate

    Hervouet, C.; Pages, D. [EDF R and D (France); Fauchon, C.; Bretelle, J.L. [EDF GDL (France); Bus, F. [EDF DPN (France)


    The comparison of the leak flow rate behavior between the previous and the new boron/lithium coordination, the second one corresponding to an higher pH during the cycle than the first one, leads to the following conclusions, confirmed by the experimental and theoretical studies: Low leak flow rate is extremely sensitive to pH in the zone of pH of primary water because the behavior of metallic oxide is changing drastically in that range of pH (from precipitation to dissolution); Leak flow rate is often maintained lower with low pH. Let's recall however that pH can not reach a too low value which could enhance corrosion product deposition, increase dose rates along the primary circuit, and lead to reactor outages due to problems on fuel assemblies. The understanding of the governing phenomena led to adapt in 2000 the reactor cooling system chemical conditioning for the French Pressurized Water reactors facing problems with the management of the stabilized leak flow rate fluctuations, once no degradation of tube bundle integrity is proved. Each part of the cycle and operating conditions lead to an advised operating action. In general, the new recommendations for the reactors facing problems with the management of low leak flow rate are based on the principle of helping the precipitation of metallic oxide within the crack and preventing their dissolution. (authors)

  19. The Use of Energy in Malaysia: Tracing Energy Flows from Primary Source to End Use

    Chinhao Chong; Weidou Ni; Linwei Ma; Pei Liu; Zheng Li


    Malaysia is a rapidly developing country in Southeast Asia that aims to achieve high-income country status by 2020; its economic growth is highly dependent on its abundant energy resources, especially natural gas and crude oil. In this paper, a complete picture of Malaysia’s energy use from primary source to end use is presented by mapping a Sankey diagram of Malaysia’s energy flows, together with ongoing trends analysis of the main factors influencing the energy flows. The results indicate t...

  20. Flow structure around high-speed train in open air

    田红旗; 黄莎; 杨明智


    According to the analysis of the turbulent intensity level around the high-speed train, the maximum turbulent intensity ranges from 0.2 to 0.5 which belongs to high turbulent flow. The flow field distribution law was studied and eight types of flow regions were proposed. They are high pressure with air stagnant region, pressure decreasing with air accelerating region, low pressure with high air flow velocity region I, turbulent region, steady flow region, low pressure with high air flow velocity region II, pressure increasing with air decelerating region and wake region. The analysis of the vortex structure around the train shows that the vortex is mainly induced by structures with complex mutation and large curvature change. The head and rear of train, the underbody structure, the carriage connection section and the wake region are the main vortex generating sources while the train body with even cross-section has rare vortexes. The wake structure development law studied lays foundation for the train drag reduction.

  1. Primary structure of myoglobins from 31 species of birds.

    Enoki, Yasunori; Ohga, Yoshimi; Ishidate, Hiromi; Morimoto, Tomotoshi


    Primary structure of myoglobins (Mbs) from 31 avian species of 15 orders were reported, although portions of the structures in the 2 species could not be determined. At least 68 of the total 153 amino acid sites were invariant all through the avian, reptilian and human Mbs, and 20 of these sites were "internal", forming the internal hydrophobic cavities in which the heme group remains wrapped. Furthermore, at 27 sites, if replaced, the replacements were mostly conservative, and 13 of the conservative sites were "internal". Thus the all 33 "internal" sites, important for structural and functional stability of the protein, have been well preserved, either invariant or conserved, during evolution from reptiles to birds and mammals. The residue 71 (E14) in 4 penguin species was not deleted as previously reported in emperor penguin Mb but occupied by Gln. The residue 121 (GH3) was deleted in all 3 species studied of Falconiformes. Out of 9 anseriforms, 5 species of different genera showed the identical structure. Secondary structures as viewed by hydropathy profiles were highly similar throughout the reptilian, avian and mammalian Mbs.

  2. Flow structure from a horizontal cylinder coincident with a free surface in shallow water flow

    Kahraman Ali


    Full Text Available Vortex formation from a horizontal cylinder coincident with a free surface of a shallow water flow having a depth of 25.4 [mm] was experimentally investigated using the PIV technique. Instantaneous and time-averaged flow patterns in the wake region of the cylinder were examined for three different cylinder diameter values under the fully developed turbulent boundary layer condition. Reynolds numbers were in the range of 1124£ Re£ 3374 and Froude numbers were in the range of 0.41 £ Fr £ 0.71 based on the cylinder diameter. It was found that a jet-like flow giving rise to increasing the flow entrainment between the core and wake regions depending on the cylinder diameter was formed between the lower surface of the cylinder and bottom surface of the channel. Vorticity intensity, Reynolds stress correlations and the primary recirculating bubble lengths were grown to higher values with increasing the cylinder diameter. On the other hand, in the case of the lowest level of the jet-like flow emanating from the beneath of the smallest cylinder, the variation of flow characteristics were attenuated significantly in a shorter distance. The variation of the reattachment location of the separated flow to the free-surface is a strong function of the cylinder diameter and the Froude number.

  3. Primary Cell Wall Structure in the Evolution of Land Plants


    Investigation of the primary cell walls of lower plants improves our understanding of the cell biology of these organisms but also has the potential to improve our understanding of cell wall structure and function in angiosperms that evolved from lower plants. Cell walls were prepared from eight species, ranging from a moss to advanced gymnosperms, and subjected to sequential chemical extraction to separate the main polysaccharide fractions. The glycosyl compositions of these fractions were then determined by gas chromatography. The results were compared among the eight plants and among data from related studies reported in the existing published reports to identify structural features that have been either highly conserved or clearly modified during evolution. Among the highly conserved features are the presence of a cellulose framework, the presence of certain hemicelluloses such as xyloglucan, and the presence of rhamnogalacturonan Ⅱ, a domain in pectic polysaccharides. Among the modified features are the abundance of mannosyl-containing hemicelluloses and the presence of methylated sugars.

  4. The Lagrangian Deformation Structure of Three-Dimensional Steady Flow

    Lester, Daniel R; Borgne, Tanguy Le; de Barros, Felipe P J


    Fluid deformation and strain history are central to wide range of fluid mechanical phenomena ranging from fluid mixing and particle transport to stress development in complex fluids and the formation of Lagrangian coherent structures (LCSs). To understand and model these processes it is necessary to quantify Lagrangian deformation in terms of Eulerian flow properties, currently an open problem. To elucidate this link we develop a Protean (streamline) coordinate transform for steady three-dimensional (3D) flows which renders both the velocity gradient and deformation gradient upper triangular. This frame not only simplifies computation of fluid deformation metrics such as fi?nite-time Lyapunov exponents (FTLEs) and elucidates the deformation structure of the flow, but moreover explicitly recovers kinematic and topological constraints upon deformation such as those related to helicity density and the Poincar\\'{e}-Bendixson theorem. We apply this transform to several classes of steady 3D flow, including helical ...


    LIU Cheng; SHEN Yong-ming


    Aquatic vegetation plays an important role in the flow structure of open channels and thus changes the fate and the transport of sediment. This article proposes a three-dimensional turbulence model by introducing vegetation density and drag force into the control equations of water flow in the presence of vegetation. The model was used to calculate the impacts of submerged vegetation on the vertical profiles of longitudinal flow velocities, the changes of the depth-averaged flow velocities in a compound channel with emergent vegetation in the floodplain, the removal of suspended sediment from the channels by emergent vegetation, and the bed changes around and in a vegetated island. Numerical investigations show that aquatic vegetation retards flow in the vegetation zone, reduces the sediment transport capacity, and contributes to erosion on both sides of the vegetated island. Calculated results agree well with experimental results.

  6. Flow Structure and Heat Transfer Between Two Disks Rotating Independently

    Chyi-Yeou Soong


    In the present paper, fluid flow and convective heat transfer between two co-axial disks rotating independently are dealt with mainly based on the author's recent research on that topic. Three rotational modes, i.e. co-rotation, rotor-stator, and counter-rotation, are considered. Theory of rotating non-isothermal fluids with the presence of disk rotation and thermal effects is addressed. Rotational buoyancy effects on the flow structure development are highlighted. Results of flow visualization and heat transfer measurements are discussed to explore the thermal flow mechanisms involved in the two-disk flows at various rotational and geometric conditions. Potential issues open to the future investigation are also proposed.

  7. Testing of a Shrouded, Short Mixing Stack Gas Eductor Model Using High Temperature Primary Flow.


    are installed in conjuction with the gas turbine geerator sets 4 -- used to provide shipboard electrical power and aot with the 20 main proplusion...pumped head P - Po (Pa-Pot) for the tertiary flow to the driving head (U Z /2gc) ofp t thz primary flow t t p2 2gc a flow rate ratio, secondary to W_...44 CP 𔃾 E-1 0 N1- 99, 5-4 x 4 00 ’a.a w I- 100. i’-U" IS !.1.° -1 -- ,4 LA W2 % 4k 101 E-44 00 1-44 1020 141 I I £ Z 0 170 r’U 103 U ~ S. ri I 0 -Co

  8. On the Vertical Structure of Seasonal, Interannual and Intraseasonal Flows


    the Vertical Structure of Seasonal, Interannual and Intraseasonal Flows b, AUTHOR(S) Steven Reino Gilbert,Major -. Pf.IFORI.MINt ORGAN!?ATION NAMW(S...AND INTRASEASONAL FLOWS by Steven Reino Gilbert A dissertation submitted to the faculty of The University of Utah in partial fulffifment of the...requirements for the degree of Doctor of Philosophy Department of Meteorology The University of Utah La ! December 1992 Copyright @ Steven Reino Gilbert 1992

  9. A thermal stack structure for measurement of fluid flow

    Zhao, Hao; Mitchell, S. J. N.; Campbell, D. H.; Gamble, Harold S.


    A stacked thermal structure for fluid flow sensing has been designed, fabricated, and tested. A double-layer polysilicon process was employed in the fabrication. Flow measurement is based on the transfer of heat from a temperature sensor element to the moving fluid. The undoped or lightly doped polysilicon temperature sensor is located on top of a heavily doped polysilicon heater element. A dielectric layer between the heater and the sensor elements provides both thermal coupling and electrical isolation. In comparison to a hot-wire flow sensor, the heating and sensing functions are separated, allowing the electrical characteristics of each to be optimized. Undoped polysilicon has a large temperature coefficient of resistance (TCR) up to 7 %/K and is thus a preferred material for the sensor. However, heavily doped polysilicon is preferred for the heater due to its lower resistance. The stacked flow sensor structure offers a high thermal sensitivity making it especially suitable for medical applications where the working temperatures are restricted. Flow rates of various fluids can be measured over a wide range. The fabricated flow sensors were used to measure the flow rate of water in the range μl - ml/min and gas (Helium) in the range 10 - 100ml/min.

  10. Flow dynamics of bank-attached instream structures

    Kang, Seokkoo


    Numerical simulations and experiments for flow past a bank-attached vane, a widely-used instream structure for stream restoration, are carried out to study the turbulent flow dynamics occurring around the structure. In the numerical simulation, the details of the natural rocks that constitute the vane are directly resolved by employing the recently developed computational fluid dynamics model of Kang et al. (2011). The time-averaged flowfield is shown to be in good agreement with the results of laboratory measurements. Analysis of the simulated flow shows that there exist two counter-rotating secondary flows cells downstream of the vane, one of which is located near the center of the channel and the other is located near the corner between the channel bed and the sidewall to which the vane is attached. The formation of the two counter-rotating secondary flow cells is shown to be linked to the plunging of the mean three-dimensional streamlines originating upstream of the vane onto a point downstream of the vane positioned on the lower part of the sidewall. The laboratory experiment also reveals the existence of such flow structures.

  11. Formation of coherent structures in 3D laminar mixing flows

    Speetjens, Michel; Clercx, Herman


    Mixing under laminar flow conditions is key to a wide variety of industrial systems of size extending from microns to meters. Examples range from the traditional (and still very relevant) mixing of viscous fluids via compact processing equipment down to emerging micro-fluidics applications. Profound insight into laminar mixing mechanisms is imperative for further advancement of mixing technology (particularly for complex micro-fluidics systems) yet remains limited to date. The present study concentrates on a fundamental transport phenomenon of potential relevance to laminar mixing: the formation of coherent structures in the web of 3D fluid trajectories due to fluid inertia. Such coherent structures geometrically determine the transport properties of the flow and better understanding of their formation and characteristics may offer ways to control and manipulate the mixing properties of laminar flows. The formation of coherent structures and its impact upon 3D transport properties is demonstrated by way of examples.

  12. Persistent Near-Surface Flow Structures from Local Helioseismology

    Howe, R; Baker, D; Harra, L; van Driel-Gesztelyi, L; Bogart, R S


    Near-surface flows measured by the ring-diagram technique of local helioseismology show structures that persist over multiple rotations. We examine these phenomena using data from the {\\em Global Oscillation Network Group} (GONG) and the {\\em Helioseismic and Magnetic Imager} (HMI) and show that a correlation analysis of the structures can be used to estimate the rotation rate as a function of latitude, giving a result consistent with the near-surface rate from global helioseismology and slightly slower than that obtained from a similar analysis of the surface magnetic field strength. At latitudes of 60$^{\\circ}$ and above the HMI flow data reveal a strong signature of a two-sided zonal flow structure. This signature may be related to recent reports of "giant cells" in solar convection.

  13. Large-scale structures in turbulent Couette flow

    Kim, Jung Hoon; Lee, Jae Hwa


    Direct numerical simulation of fully developed turbulent Couette flow is performed with a large computational domain in the streamwise and spanwise directions (40 πh and 6 πh) to investigate streamwise-scale growth mechanism of the streamwise velocity fluctuating structures in the core region, where h is the channel half height. It is shown that long streamwise-scale structures (> 3 h) are highly energetic and they contribute to more than 80% of the turbulent kinetic energy and Reynolds shear stress, compared to previous studies in canonical Poiseuille flows. Instantaneous and statistical analysis show that negative-u' structures on the bottom wall in the Couette flow continuously grow in the streamwise direction due to mean shear, and they penetrate to the opposite moving wall. The geometric center of the log layer is observed in the centerline with a dominant outer peak in streamwise spectrum, and the maximum streamwise extent for structure is found in the centerline, similar to previous observation in turbulent Poiseuille flows at high Reynolds number. Further inspection of time-evolving instantaneous fields clearly exhibits that adjacent long structures combine to form a longer structure in the centerline. This research was supported by Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Education (NRF-2014R1A1A2057031).

  14. Short- and Long- Time Transport Structures in a Three Dimensional Time Dependent Flow

    Chabreyrie, Rodolphe; Llewellyn Smith, Stefan


    Lagrangian transport structures for three-dimensional and time-dependent fluid flows are of great interest in numerous applications, particularly for geophysical or oceanic flows. In such flows, chaotic transport and mixing can play important environmental and ecological roles, for examples in pollution spills or plankton migration. In such flows, where simulations or observations are typically available only over a short time, understanding the difference between short-time and long-time transport structures is critical. In this talk, we use a set of classical (i.e. Poincaré section, Lyapunov exponent) and alternative (i.e. finite time Lyapunov exponent, Lagrangian coherent structures) tools from dynamical systems theory that analyze chaotic transport both qualitatively and quantitatively. With this set of tools we are able to reveal, identify and highlight differences between short- and long-time transport structures inside a flow composed of a primary horizontal contra-rotating vortex chain, small lateral oscillations and a weak Ekman pumping. The difference is mainly the existence of regular or extremely slowly developing chaotic regions that are only present at short time. This research was funded by the ONR MURI Dynamical Systems Theory and Lagrangian Data Assimilation in 3D+1 Geophysical Fluid Dynamics.

  15. Detection of coherent structures in photospheric turbulent flows

    Chian, Abraham C.-L.; Rempel, Erico L. [National Institute for Space Research (INPE), World Institute for Space Environment Research (WISER), P.O. Box 515, 12227-010 São José dos Campos-SP (Brazil); Aulanier, Guillaume; Schmieder, Brigitte [Observatoire de Paris, LESIA, CNRS, F-92190 Meudon (France); Shadden, Shawn C. [Department of Mechanical Engineering, University of California, Berkeley, CA 94720 (United States); Welsch, Brian T. [Space Science Laboratory, University of California, Berkeley, CA 94720 (United States); Yeates, Anthony R., E-mail:, E-mail: [Department of Mathematical Sciences, Durham University, Durham DH1 3LE (United Kingdom)


    We study coherent structures in solar photospheric flows in a plage in the vicinity of the active region AR 10930 using the horizontal velocity data derived from Hinode/Solar Optical Telescope magnetograms. Eulerian and Lagrangian coherent structures (LCSs) are detected by computing the Q-criterion and the finite-time Lyapunov exponents of the velocity field, respectively. Our analysis indicates that, on average, the deformation Eulerian coherent structures dominate over the vortical Eulerian coherent structures in the plage region. We demonstrate the correspondence of the network of high magnetic flux concentration to the attracting Lagrangian coherent structures (aLCSs) in the photospheric velocity based on both observations and numerical simulations. In addition, the computation of aLCS provides a measure of the local rate of contraction/expansion of the flow.

  16. Aerodynamic structures and processes in rotationally augmented flow fields

    Schreck, S.J.; Sørensen, Niels N.; Robinson, M.C.


    . Experimental measurements consisted of surface pressure data statistics used to infer sectional boundary layer state and to quantify normal force levels. Computed predictions included high-resolution boundary layer topologies and detailed above-surface flow field structures. This synergy was exploited...... to reliably identify and track pertinent features in the rotating blade boundary layer topology as they evolved in response to varying wind speed. Subsequently, boundary layer state was linked to above-surface flow field structure and used to deduce mechanisms; underlying augmented aerodynamic force...

  17. Dynamics of generalized Gaussian polymeric structures in random layered flows

    Katyal, Divya; Kant, Rama


    We develop a formalism for the dynamics of a flexible branched polymer with arbitrary topology in the presence of random flows. This is achieved by employing the generalized Gaussian structure (GGS) approach and the Matheron-de Marsily model for the random layered flow. The expression for the average square displacement (ASD) of the center of mass of the GGS is obtained in such flow. The averaging is done over both the thermal noise and the external random flow. Although the formalism is valid for branched polymers with various complex topologies, we mainly focus here on the dynamics of the flexible star and dendrimer. We analyze the effect of the topology (the number and length of branches for stars and the number of generations for dendrimers) on the dynamics under the influence of external flow, which is characterized by their root-mean-square velocity, persistence flow length, and flow exponent α . Our analysis shows two anomalous power-law regimes, viz., subdiffusive (intermediate-time polymer stretching and flow-induced diffusion) and superdiffusive (long-time flow-induced diffusion). The influence of the topology of the GGS is unraveled in the intermediate-time regime, while the long-time regime is only weakly dependent on the topology of the polymer. With the decrease in the value of α , the magnitude of the ASD decreases, while the temporal exponent of the ASD increases in both the time regimes. Also there is an increase in both the magnitude of the ASD and the crossover time (from the subdiffusive to the superdiffusive regime) with an increase in the total mass of the polymeric structure.

  18. Observations of pockmark flow structure in Belfast Bay, Maine, Part 2: evidence for cavity flow

    Fandel, Christina L.; Lippmann, Thomas C.; Foster, Diane L.; Brothers, Laura L.


    Pockmark flow circulation patterns were investigated through current measurements along the rim and center of two pockmarks in Belfast Bay, Maine. Observed time-varying current profiles have a complex vertical and directional structure that rotates significantly with depth and is strongly dependent on the phase of the tide. Observations of the vertical profiles of horizontal velocities in relation to relative geometric parameters of the pockmark are consistent with circulation patterns described qualitatively by cavity flow models (Ashcroft and Zhang 2005). The time-mean behavior of the shear layer is typically used to characterize cavity flow, and was estimated using vorticity thickness to quantify the growth rate of the shear layer horizontally across the pockmark. Estimated positive vorticity thickness spreading rates are consistent with cavity flow predictions, and occur at largely different rates between the two pockmarks. Previously modeled flow (Brothers et al. 2011) and laboratory measurements (Pau et al. 2014) over pockmarks of similar geometry to those examined herein are also qualitatively consistent with cavity flow circulation, suggesting that cavity flow may be a good first-order flow model for pockmarks in general.

  19. Observations of pockmark flow structure in Belfast Bay, Maine, Part 2: evidence for cavity flow

    Fandel, Christina L.; Lippmann, Thomas C.; Foster, Diane L.; Brothers, Laura L.


    Pockmark flow circulation patterns were investigated through current measurements along the rim and center of two pockmarks in Belfast Bay, Maine. Observed time-varying current profiles have a complex vertical and directional structure that rotates significantly with depth and is strongly dependent on the phase of the tide. Observations of the vertical profiles of horizontal velocities in relation to relative geometric parameters of the pockmark are consistent with circulation patterns described qualitatively by cavity flow models (Ashcroft and Zhang 2005). The time-mean behavior of the shear layer is typically used to characterize cavity flow, and was estimated using vorticity thickness to quantify the growth rate of the shear layer horizontally across the pockmark. Estimated positive vorticity thickness spreading rates are consistent with cavity flow predictions, and occur at largely different rates between the two pockmarks. Previously modeled flow (Brothers et al. 2011) and laboratory measurements (Pau et al. 2014) over pockmarks of similar geometry to those examined herein are also qualitatively consistent with cavity flow circulation, suggesting that cavity flow may be a good first-order flow model for pockmarks in general.

  20. Results of the evaluation and preliminary validation of a primary LNG mass flow standard

    van der Beek, Mijndert; Lucas, Peter; Kerkhof, Oswin; Mirzaei, Maria; Blom, Gerard


    LNG custody transfer measurements at large terminals have been based on ship tank level gauging for more than 50 years. Flow meter application has mainly been limited to process control in spite of the promise of simplified operations, potentially smaller uncertainties and better control over the measurements for buyers. The reason for this has been the lack of LNG flow calibration standards as well as written standards. In the framework of the EMRP1 ‘Metrology for LNG’ project, Van Swinden Laboratory (VSL) has developed a primary LNG mass flow standard. This standard is so far the only one in the world except for a liquid nitrogen flow standard at the National Institute of Standards and Technology (NIST). The VSL standard is based on weighing and holds a Calibration and Measurement Capability (CMC) of 0.12% to 0.15%. This paper discusses the measurement principle, results of the uncertainty validation with LNG and the differences between water and LNG calibration results of four Coriolis mass flow meters. Most of the calibrated meters do not comply with their respective accuracy claims. Recommendations for further improvement of the measurement uncertainty will also be discussed.

  1. Zonal structure of unbounded external-flow and aerodynamics

    Liu, Luoqin; Wu, Jiezhi


    This paper starts from the far-field behaviours of velocity field in externally-unbounded flow. We find that the well-known algebraic decay of disturbance velocity as derived kinematically is too conservative. Once the kinetics is taken into account by working on the fundamental solutions of far-field linearized Navier-Stokes equations, it is proven that the furthest far-field zone adjacent to the uniform fluid at infinity must be unsteady, viscous and compressible, where all disturbances degenerate to sound waves that decay exponentially. But this optimal rate does not exist in some commonly used simplified flow models, such as steady flow, incompressible flow and inviscid flow, because they actually work in true subspaces of the unbounded free space, which are surrounded by further far fields of different nature. This finding naturally leads to a zonal structure of externally-unbounded flow field. The significance of the zonal structure is demonstrated by its close relevance to existing theories of aerodyna...

  2. Structures and scaling laws of turbulent Couette flow

    Oberlack, Martin; Avsarkisov, Victor; Hoyas, Sergio; Rosteck, Andreas; Garcia-Galache, Jose P.; Frank, Andy


    We conducted a set of large scale DNS of turbulent Couette flow with the two key objectives: (i) to better understand large scale coherent structures and (ii) to validate new Lie symmetry based turbulent scaling laws for the mean velocity and higher order moments. Though frequently reported in the literature large scale structures pose a serious constraint on our ability to conduct DNS of turbulent Couette flow as the largest structures grow with increasing Re#, while at the same time Kolmogorov scale decreases. Other than for the turbulent Poiseuille flow a too small box is immediately visible in low order statistics such as the mean and limited our DNS to Reτ = 550 . At the same time we observed that scaling of the mean is peculiar as it involves a certain statistical symmetry which has never been observed for any other parallel wall-bounded turbulent shear flow. Symmetries such as Galilean group lie at the heart of fluid dynamics, while for turbulence statistics due to the multi-point correlation equations (MPCE) additional statistical symmetries are admitted. Most important, symmetries are the essential to construct exact solutions to the MPCE, which with the new above-mentioned special statistical symmetry led to a new turbulent scaling law for the Couette flow. DFG Grant No; KH 257/2-1.

  3. Coherent structures in compressible free-shear-layer flows

    Aeschliman, D.P.; Baty, R.S. [Sandia National Labs., Albuquerque, NM (United States). Engineering Sciences Center; Kennedy, C.A.; Chen, J.H. [Sandia National Labs., Livermore, CA (United States). Combustion and Physical Sciences Center


    Large scale coherent structures are intrinsic fluid mechanical characteristics of all free-shear flows, from incompressible to compressible, and laminar to fully turbulent. These quasi-periodic fluid structures, eddies of size comparable to the thickness of the shear layer, dominate the mixing process at the free-shear interface. As a result, large scale coherent structures greatly influence the operation and efficiency of many important commercial and defense technologies. Large scale coherent structures have been studied here in a research program that combines a synergistic blend of experiment, direct numerical simulation, and analysis. This report summarizes the work completed for this Sandia Laboratory-Directed Research and Development (LDRD) project.

  4. Structural integrated sensor and actuator systems for active flow control

    Behr, Christian; Schwerter, Martin; Leester-Schädel, Monika; Wierach, Peter; Dietzel, Andreas; Sinapius, Michael


    An adaptive flow separation control system is designed and implemented as an essential part of a novel high-lift device for future aircraft. The system consists of MEMS pressure sensors to determine the flow conditions and adaptive lips to regulate the mass flow and the velocity of a wall near stream over the internally blown Coanda flap. By the oscillating lip the mass flow in the blowing slot changes dynamically, consequently the momentum exchange of the boundary layer over a high lift flap required mass flow can be reduced. These new compact and highly integrated systems provide a real-time monitoring and manipulation of the flow conditions. In this context the integration of pressure sensors into flow sensing airfoils of composite material is investigated. Mechanical and electrical properties of the integrated sensors are investigated under mechanical loads during tensile tests. The sensors contain a reference pressure chamber isolated to the ambient by a deformable membrane with integrated piezoresistors connected as a Wheatstone bridge, which outputs voltage signals depending on the ambient pressure. The composite material in which the sensors are embedded consists of 22 individual layers of unidirectional glass fiber reinforced plastic (GFRP) prepreg. The results of the experiments are used for adapting the design of the sensors and the layout of the laminate to ensure an optimized flux of force in highly loaded structures primarily for future aeronautical applications. It can be shown that the pressure sensor withstands the embedding process into fiber composites with full functional capability and predictable behavior under stress.

  5. Monocular concurrent recovery of structure and motion scene flow

    Amar eMitiche


    Full Text Available This paper describes a variational method of joint three-dimensional structure and motion scene flow recovery from a single image sequence. A basic scheme is developed by minimizing a functional with a term of conformity of scene flow and depth to the image sequence spatiotemporal variations, and quadratic smoothness regularization terms. The data term follows by re-writing optical velocity in the optical flow gradient constraint in terms of scene flow and depth. As a result, this problem statement is analogous to the classical Horn and Schunck optical flow formulation except that it involves scene flow and depth rather than image motion. When discretized, the Euler-Lagrange equations give a large scale sparse system of linear equations in the unknowns of the scene flow three coordinates and depth. The equations can be ordered in such a way that its matrix is symmetric positive definite such that they can be solved efficiently by Gauss-Seidel iterations. Experiments are shown to verify the scheme’s validity and efficiency.

  6. Computational Fluid Dynamics Simulation of Multiphase Flow in Structured Packings

    Saeed Shojaee


    Full Text Available A volume of fluid multiphase flow model was used to investigate the effective area and the created liquid film in the structured packings. The computational results revealed that the gas and liquid flow rates play significant roles in the effective interfacial area of the packing. In particular, the effective area increases as the flow rates of both phases increase. Numerical results were compared with the Brunazzi and SRP models, and a good agreement between them was found. Attention was given to the process of liquid film formation in both two-dimensional (2D and three-dimensional (3D models. The current study revealed that computational fluid dynamics (CFD can be used as an effective tool to provide information on the details of gas and liquid flows in complex packing geometries.

  7. Structure formation of surfactant membranes under shear flow

    Shiba, Hayato; Noguchi, Hiroshi; Gompper, Gerhard


    Shear-flow-induced structure formation in surfactant-water mixtures is investigated numerically using a meshless-membrane model in combination with a particle-based hydrodynamics simulation approach for the solvent. At low shear rates, uni-lamellar vesicles and planar lamellae structures are formed at small and large membrane volume fractions, respectively. At high shear rates, lamellar states exhibit an undulation instability, leading to rolled or cylindrical membrane shapes oriented in the flow direction. The spatial symmetry and structure factor of this rolled state agree with those of intermediate states during lamellar-to-onion transition measured by time-resolved scatting experiments. Structural evolution in time exhibits a moderate dependence on the initial condition.

  8. On flow structures and the hierarchy of shears

    Dif-Pradalier, G.; Diamond, P. H.; McDevitt, C. J.; Sarazin, Y.; Grandgirard, V.; Garbet, X.; Chang, C. S.; Ku, S.


    We investigate the consequences of mean profile dynamics in flux-driven gyrokinetics. We report the emergence of a novel flow structure in plasma turbulence, which we call the ``ExB staircase.'' This structure connects to strong, standing corrugations in the plasma profiles, which is not related to rational q surfaces. We also show that the ExB shear associated to these mean profile corrugations is strongly dominant as compared to the usually-invoked zonal flow shear. Discussion of the dynamics of mean profiles (i) as another channel for turbulence regulation, missing in ``usual'' gyrokinetic approaches, (ii) its connection with turbulent stresses and the transport of potential vorticity, its link (iii) to the observed flow patterns and (iv) to the question of locality vs non-locality in transport is presented.

  9. Three Kinds of Velocity Structure Function in Turbulent Flows

    LIU Wei; JIANG Nan


    Based on the local multi-scale eddy structures in turbulent flows, we elucidate the essential difference between the real turbulent field with a finite Reynolds number and the Kolmogorov fully developed random field. The motion of fluid particles in the real turbulent field is not fully random. There exist multi-scale structures due to the effect of viscosity. Actually the movements of fluid particles in the turbulent field are restricted by such eddy structures. Furthermore, concept of the locally averaged velocity structure function is put forward to describe the relative strain distortion of two adjacent turbulent eddy structures at a certain scale. The time sequence of the longitudinal velocity component at different vertical locations in turbulent boundary layer has been elaborately measured by the constant temperature anemometry of model IFA-300 in a wind tunnel. The experiment proves that the locally averaged velocity structure function is in agreement with the wavelet-coefficient structure function.

  10. Flow-induced structured phase in nonionic micellar solutions.

    Cardiel, Joshua J; Tonggu, Lige; de la Iglesia, Pablo; Zhao, Ya; Pozzo, Danilo C; Wang, Liguo; Shen, Amy Q


    In this work, we consider the flow of a nonionic micellar solution (precursor) through an array of microposts, with focus on its microstructural and rheological evolution. The precursor contains polyoxyethylene(20) sorbitan monooleate (Tween-80) and cosurfactant monolaurin (ML). An irreversible flow-induced structured phase (NI-FISP) emerges after the nonionic precursor flows through the hexagonal micropost arrays, when subjected to strain rates ~10(4) s(-1) and strain ~10(3). NI-FISP consists of close-looped micellar bundles and multiconnected micellar networks as evidenced by transmission electron microscopy (TEM) and cryo-electron microscopy (cryo-EM). We also conduct small-angle neutron scattering (SANS) measurements in both precursor and NI-FISP to illustrate the structural transition. We propose a potential mechanism for the NI-FISP formation that relies on the micropost arrays and the flow kinematics in the microdevice to induce entropic fluctuations in the micellar solution. Finally, we show that the rheological variation from a viscous precursor solution to a viscoelastic micellar structured phase is associated with the structural evolution from the precursor to NI-FISP.

  11. Turbulent pipe flow: Statistics, Re-dependence, structures and similarities with channel and boundary layer flows

    El Khoury, George K.; Schlatter, Philipp; Brethouwer, Geert; Johansson, Arne V.


    Direct numerical simulation data of fully developed turbulent pipe flow are extensively compared with those of turbulent channel flow and zero-pressure-gradient boundary layer flow for Reτ up to 1000. In the near-wall region, a high degree of similarity is observed in the three flow cases in terms of one-point statistics, probability density functions of the wall-shear stress and pressure, spectra, Reynolds stress budgets and advection velocity of the turbulent structures. This supports the notion that the near-wall region is universal for pipe and channel flow. Probability density functions of the wall shear stress, streamwise turbulence intensities, one-dimensional spanwise/azimuthal spectra of the streamwise velocity and Reynolds-stress budgets are very similar near the wall in the three flow cases, suggesting that the three canonical wall-bounded flows share many features. In the wake region, the mean streamwise velocity and Reynolds stress budgets show some expected differences.

  12. Quasi-Stability of the Primary Flow in a Cone and Plate Viscometer

    Azerad, Pascal; Bänsch, Eberhard

    We investigate the flow between a shallow rotating cone and a stationary plate. This cone and plate device is used in rheometry, haemostasis as well as in food industry to study the properties of the flow w.r.t. shear stress. Physical experiments and formal computations show that close to the apex the flow is approximately azimuthal and the shear-stress is constant within the device, the quality of the approximation being controlled essentially by the single parameter Re ɛ2, where Re is the Reynolds number and ɛ the thinness of the cone-plate gap. We establish this fact by means of rigorous energy estimates and numerical simulations. Surprisingly enough, this approximation is valid though the primary flow is not itself a solution of the Navier-Stokes equations, and it does not even fulfill the correct boundary conditions, which are in this particular case discontinuous along a line, thus not allowing for a usual Leray solution. To overcome this difficulty we construct a suitable corrector.

  13. Amino Acid Molecular Units: Building Primary and Secondary Protein Structures

    Aparecido R. Silva


    Full Text Available In order to guarantee the learning quality and suitable knowledge  use  about structural biology, it is fundamental to  exist, since the beginning of  students’ formation, the possibility of clear visualization of biomolecule structures. Nevertheless, the didactic books can only bring  schematic  drawings; even more elaborated figures and graphic computation  do not permit the necessary interaction.  The representation of three-dimensional molecular structures with ludic models, built with representative units, have supplied to the students and teachers a successfully experience to  visualize such structures and correlate them to the real molecules.  The design and applicability of the representative units were discussed with researchers and teachers before mould implementation.  In this stage  it  will be presented the  developed  kit  containing the  representative  plastic parts of the main amino acids.  The kit can demonstrate the interaction among the amino acids  functional groups  (represented by colors, shapes,  sizes and  the peptidic bonds between them  facilitating the assembly and visuali zation of the primary and secondary protein structure.  The models were designed for  Ca,  amino,  carboxyl groups  and  hydrogen. The  lateral chains have  well defined models that represent their geometrical shape.  The completed kit set  will be presented in this meeting (patent requested.  In the last phase of the project will be realized  an effective evaluation  of the kit  as a facilitative didactic tool of the teaching/learning process in the Structural Molecular Biology area.

  14. The influence of admission glucose on epicardial and microvascular flow after primary angioplasty


    Background Patients with elevated admission glucose levels may be at increased risk of death after myocardial infarction, independent of other baseline risk factors and more severe coronary artery disease. However, data regarding admission glucose and epicardial and microvascular flow after primary angioplasty is limited.Methods Angioplasty was performed in 308 ST-segment elevated myocardial infarction patients. Patients were divided into 3 groups on the basis of admission glucose level: group 1, <7.8 mmol/L; group 2, (7.8 - 11.0) mmol/L; and group 3, ≥11.0 mmol/L. Results Compared with group 1, patients in group 2 and group 3 were more often female and older. Triglycerides (TG) in group 3 were significantly higher than group 1. At angiography, they more frequently had 2-vessel or 3-vessel disease. In the infarct-related artery, there was no relationship between hyperglycemia and thrombolysis in myocardial infarction (TIMI) 3 flow after percutaneous coronary intervention (PCI) (89.7%, 86.0% and 86.3%, P=NS). However, corrected TIMI frame count (CTFC) in group 2 and group 3 were more than group 1. TIMI myocardial perfusion grade (TMPG) 0-1 grade among patients with hyperglycemia after PCI were more frequent (30.9% and 29.0% vs 17.3%, P<0.05). There was less frequent complete ST-segment resolution (STR) and early T wave inversion among patients with hyperglycemia after PCI. Conclusion Elevated admission glucose levels in ST-segment elevation myocardial infarction patients treated with primary PCI are independently associated with impaired microvascular flow. Abnormal microvascular flow may contribute at least in part to the poor outcomes observed in patients with elevated admission glucose.

  15. Analysis and representation of complex structures in separated flows

    Helman, James; Hesselink, Lambertus


    We discuss our recent work on extraction and visualization of topological information in separated fluid flow data sets. As with scene analysis, an abstract representation of a large data set can greatly facilitate the understanding of complex, high-level structures. When studying flow topology, such a representation can be produced by locating and characterizing critical points in the velocity field and generating the associated stream surfaces. In 3D flows, the surface topology serves as the starting point. The 2D tangential velocity field near the surface of the body is examined for critical points. The tangential velocity field is integrated out along the principal directions of certain classes of critical points to produce curves depicting the topology of the flow near the body. The points and curves are linked to form a skeleton representing the 2D vector field topology. This skeleton provides a basis for analyzing the 3D structures associated with the flow separation. The points along the separation curves in the skeleton are used to start tangent curve integrations. Integration origins are successively refined to produce stream surfaces. The map of the global topology is completed by generating those stream surfaces associated with 3D critical points.

  16. Flow directionality, mountain barriers and functional traits determine diatom metacommunity structuring of high mountain streams.

    Dong, Xiaoyu; Li, Bin; He, Fengzhi; Gu, Yuan; Sun, Meiqin; Zhang, Haomiao; Tan, Lu; Xiao, Wen; Liu, Shuoran; Cai, Qinghua


    Stream metacommunities are structured by a combination of local (environmental filtering) and regional (dispersal) processes. The unique characters of high mountain streams could potentially determine metacommunity structuring, which is currently poorly understood. Aiming at understanding how these characters influenced metacommunity structuring, we explored the relative importance of local environmental conditions and various dispersal processes, including through geographical (overland), topographical (across mountain barriers) and network (along flow direction) pathways in shaping benthic diatom communities. From a trait perspective, diatoms were categorized into high-profile, low-profile and motile guild to examine the roles of functional traits. Our results indicated that both environmental filtering and dispersal processes influenced metacommunity structuring, with dispersal contributing more than environmental processes. Among the three pathways, stream corridors were primary pathway. Deconstructive analysis suggested different responses to environmental and spatial factors for each of three ecological guilds. However, regardless of traits, dispersal among streams was limited by mountain barriers, while dispersal along stream was promoted by rushing flow in high mountain stream. Our results highlighted that directional processes had prevailing effects on metacommunity structuring in high mountain streams. Flow directionality, mountain barriers and ecological guilds contributed to a better understanding of the roles that mountains played in structuring metacommunity.

  17. Dynamical structure of magnetized dissipative accretion flow around black holes

    Sarkar, Biplob; Das, Santabrata


    We study the global structure of optically thin, advection dominated, magnetized accretion flow around black holes. We consider the magnetic field to be turbulent in nature and dominated by the toroidal component. With this, we obtain the complete set of accretion solutions for dissipative flows where bremsstrahlung process is regarded as the dominant cooling mechanism. We show that rotating magnetized accretion flow experiences virtual barrier around black hole due to centrifugal repulsion that can trigger the discontinuous transition of the flow variables in the form of shock waves. We examine the properties of the shock waves and find that the dynamics of the post-shock corona (PSC) is controlled by the flow parameters, namely viscosity, cooling rate and strength of the magnetic field, respectively. We separate the effective region of the parameter space for standing shock and observe that shock can form for wide range of flow parameters. We obtain the critical viscosity parameter that allows global accretion solutions including shocks. We estimate the energy dissipation at the PSC from where a part of the accreting matter can deflect as outflows and jets. We compare the maximum energy that could be extracted from the PSC and the observed radio luminosity values for several supermassive black hole sources and the observational implications of our present analysis are discussed.

  18. Three-dimensional flow and turbulence structure in electrostatic precipitator

    Ullum, Thorvald Uhrskov; Larsen, Poul Scheel; Özcan, Oktay


    Stereo PIV is employed to study the three-dimensional velocity and turbulence fields in a laboratory model of a negative corona, barbed-wire, smooth-plate, electrostatic precipitator (figure 1). The study is focused on determining the parametric effects of axial development, mean current density Jm...... and bulk velocity U0 on secondary flows and turbulence levels and structures due to the action of the three-dimensional electrostatic field on the charged gas. At constant bulk velocity (U0 = 1 m/s) and current density (Jm = 0.4 mA/m2), secondary flows in the form of rolls of axial vorticity with swirl...

  19. Turbulent statistics and flow structures in spanwise-rotating turbulent plane Couette flows

    Gai, Jie; Xia, Zhenhua; Cai, Qingdong; Chen, Shiyi


    A series of direct numerical simulations of spanwise-rotating turbulent plane Couette flows at a Reynolds number of 1300 with rotation numbers Ro between 0 and 0.9 is carried out to investigate the effects of anticyclonic rotation on turbulent statistics and flow structures. Several typical turbulent statistics are presented, including the mean shear rate at the centerline, the wall-friction Reynolds number, and volume-averaged kinetic energies with respect to the secondary flow field, turbulent field, and total fluctuation field. Our results show that the rotation changes these quantities in different manners. Volume-averaged balance equations for kinetic energy are analyzed and it turns out that the interaction term acts as a kinetic energy bridge that transfers energy from the secondary flow to the turbulent fluctuations. Several typical flow regimes are identified based on the correlation functions across the whole channel and flow visualizations. The two-dimensional roll cells are observed at weak rotation Ro=0.01 , where alternant clustering of vortices appears. Three-dimensional roll cells emerge around Ro≈0.02 , where the clustering of vortices shows the meandering and bifurcating behavior. For moderate rotation 0.07 ≲Ro≲0.36 , well-organized structures are observed, where the herringbonelike vortices are clustered between streaks from the top view of three-dimensional flow visualization and form annuluses. More importantly, the vortices are rather confined to one side of the walls when Ro≤0.02 and are inclined from the bottom to upper walls when Ro≥0.07 .

  20. Experimental investigation of flow-structure interaction between a model biofilm streamer and water flow

    Kazemifar, Farzan; Blois, Gianluca; Sinha, Sumit; Hardy, Richard; Best, James; Sambrook Smith, Gregory; Christensen, Kenneth


    Biofilms are permeable and deformable material whose bulk structure is composed of extracellular polymeric substance (EPS) that houses bacterial colonies. The EPS is responsible for the mechanical properties of the biofilm. In this study we investigate the fluid-structure interaction between a model biofilm streamer and water flow in a closed-loop water channel in the laminar and transitional flow regimes, using the particle image velocimetry (PIV) technique. The model streamer is fabricated from acrylamide polymer hydrogel. The purpose for using this material is twofold: 1) its mechanical properties (i.e. elastic modulus) can be tuned by controlling its chemical composition, 2) the hydrogel is transparent with a refractive index (RI) very close to that of water, thus minimizing the optical distortions for flow visualization. The velocity vector fields obtained from PIV measurements are used to investigate the temporal evolution of the flow structure in the vicinity of the streamer, focusing on the vortex shedding mechanism and the resulting oscillations of the streamer.

  1. Primary succession of Hawaiian montane rain forest on a chronosequence of eight lava flows

    Kitayama, K.; Mueller-Dombois, D. [Univ. of Hawaii at Manoa, Honolulu, HI, (United States) Dept. of Botany; Vitousek, P.M. [Stanford Univ., Stanford, CA (United States) Dept. of Biological Sciences


    The primary-successional sere of a Hawaiian montane rain forest was inferred from an age sequence of eight closely located `a`a flows (clinker type lava); 8, 50, 140, ca. 300, ca. 400, ca. 1400, ca. 3000 and ca.9000 yr, on a windward slope of Mauna Loa, Hawaii. All study sites (0.2 ha each) were at 1120-1250 m a.s.l. with 4000 mm mean annual rainfall. The 400-yr, 1400-yr, and 9000-yr flows had younger volcanic ash deposits, while the others were pure lava. Comparisons of tree size and foliar nutrients suggested that ash increased the availability of nitrogen, and subsequently standing biomass. An Unweighted Pair Group Cluster Analysis on the samples (flows) using quantitative vascular species composition revealed that clusters were correlated with age regardless of the substrate types (pure lava vs. ash), and an indirect ordination on the samples suggested that the sequence of sample scores along axis 1 was perfectly correlated with the age sequence. Although ash deposits increased biomass, they did not affect the sequence of the successional sere. Both pubescent and glabrous varieties of Metrosideros polymorpha (Myrtaceae) dominated upper canopy layers on all flows {>=} 50 yr and {<=} 1400 yr, but the pubescent variety was replaced by the glabrous on the flows {>=} 3000 yr. Lower layers were dominated initially by a mated fern, Dicranopteris linearis, up to 300 yr, and subsequently by tree ferns, Cibotium spp., to 9000 yr. The cover of Cibotium declined sightly after 3000 yr, while other native herb and shrub species increased. 43 refs, 7 figs, 4 tabs

  2. Numerical modelling of structural controls on fluid flow and mineralization

    Yanhua Zhang


    Full Text Available This paper presents the results of a set of numerical models focussing on structural controls on hydrothermal mineralization. We first give an overview of natural phenomena of structurally-controlled ore formation and the background theory and mechanisms for such controls. We then provide the results of a group of simple 2D numerical models validated through comparison with Cu-vein structure observed near the Shilu Copper deposit (Yangchun, Guangdong Province, China and finally a case study of 3D numerical modelling applied to the Hodgkinson Province in North Queensland (Australia. Two modelling approaches, discrete deformation modelling and continuum coupled deformation and fluid flow modelling, are involved. The 2D model-derived patterns are remarkably consistent with the Cu-vein structure from the Shilu Copper deposit, and show that both modelling approaches can realistically simulate the mechanical behaviours of shear and dilatant fractures. The continuum coupled deformation and fluid flow model indicates that pattern of the Cu-veins near the Shilu deposit is the result of shear strain localization, development of dilation and fluid focussing into the dilatant fracture segments. The 3D case-study models (with deformation and fluid flow coupling on the Hodgkinson Province generated a number of potential gold mineralization targets.

  3. Structural analysis of red blood cell aggregates under shear flow.

    Chesnutt, J K W; Marshall, J S


    A set of measures of red blood cell (RBC) aggregates are developed and applied to examine the aggregate structure under plane shear and channel flows. Some of these measures are based on averages over the set of red blood cells which are in contact with each other at a given time. Other measures are developed by first fitting an ellipse to the planar projection of the aggregate, and then examining the area and aspect ratio of the fit ellipse as well as the orientations of constituent RBCs with respect to the fit ellipse axes. The aggregate structural measures are illustrated using a new mesoscale computational model for blood cell transport, collision and adhesion. The sensitivity of this model to change in adhesive surface energy density and shear rate on the aggregate structure is examined. It is found that the mesoscale model predictions exhibit reasonable agreement with experimental and theoretical data for blood flow in plane shear and channel flows. The new structural measures are used to examine the differences between predictions of two- and three-dimensional computations of the aggregate formation, showing that two-dimensional computations retain some of the important aspects of three-dimensional computations.

  4. Asthma care: Structural foundations at primary health care at Al-Qassim region, Saudi Arabia

    AL-Haddad Nasser


    Full Text Available BACKGROUND: Proper structural foundations for asthma care at primary health care centers [PHCCs], are of essential importance, regarding its management. OBJECTIVE: To assess the adherence of PHCCs to the recommended structural foundation for asthma care. MATERIALS AND METHODS: 35 PHCCs were selected in a cluster random fashion. A questionnaire for structural standards was designed, based on the Saudi national protocol for the management of asthma (SNPMA. A physician and a nurse, each from PHCC, were trained for data collection. Structural facilities deficiency was arbitrarily classified into: least deficient (>75%, moderate to severe deficient (25-75% and most deficient (< 25%. RESULTS: The total population registered, was 131190 [urban: 85701 (65.4%, rural: 45489 (34.6%]. Total registered asthmatics was 4093 [urban: 2585 (63.1%, rural: 1508 (36.9%]. The asthma prevalence rate did not differ significantly between urban (3% and rural (3.3% areas . Structural facilities distribution for asthma care, did not significantly vary among urban and rural PHCCs and none of them fulfilled 100% of the desired standards. The least deficient, were the availability of asthma register and salbutamol, in its various forms. The moderately to severely deficient were the SNPMA, peak flow meter (PFM, nebulizer system, Theophylline and systemic corticosteroid. However, they were most deficient in trained doctors and nurses, record charts for Peak flow meter, spacer, educational material and inhalers of corticosteroid or cromoglycate. CONCLUSION: Proper structural foundations for asthma care at PHCCs, at AL-Qassim region, were below the desired national standards. They were most deficient in trained doctors and nurses, record charts for PFM, spacers, educational material and anti-inflammatory inhalers. Future health directorate strategies have to provide such beneficial interventions for proper asthma care.

  5. Buoyancy Effects on Flow Structure and Instability of Low-Density Gas Jets

    Pasumarthi, Kasyap Sriramachandra


    A low-density gas jet injected into a high-density ambient gas is known to exhibit self-excited global oscillations accompanied by large vortical structures interacting with the flow field. The primary objective of the proposed research is to study buoyancy effects on the origin and nature of the flow instability and structure in the near-field of low-density gas jets. Quantitative rainbow schlieren deflectometry, Computational fluid dynamics (CFD) and Linear stability analysis were the techniques employed to scale the buoyancy effects. The formation and evolution of vortices and scalar structure of the flow field are investigated in buoyant helium jets discharged from a vertical tube into quiescent air. Oscillations at identical frequency were observed throughout the flow field. The evolving flow structure is described by helium mole percentage contours during an oscillation cycle. Instantaneous, mean, and RMS concentration profiles are presented to describe interactions of the vortex with the jet flow. Oscillations in a narrow wake region near the jet exit are shown to spread through the jet core near the downstream location of the vortex formation. The effects of jet Richardson number on characteristics of vortex and flow field are investigated and discussed. The laminar, axisymmetric, unsteady jet flow of helium injected into air was simulated using CFD. Global oscillations were observed in the flow field. The computed oscillation frequency agreed qualitatively with the experimentally measured frequency. Contours of helium concentration, vorticity and velocity provided information about the evolution and propagation of vortices in the oscillating flow field. Buoyancy effects on the instability mode were evaluated by rainbow schlieren flow visualization and concentration measurements in the near-field of self-excited helium jets undergoing gravitational change in the microgravity environment of 2.2s drop tower at NASA John H. Glenn Research Center. The jet

  6. Primary structural analysis of sulfhydryl protease inhibitors from pineapple stem.

    Reddy, M N; Keim, P S; Heinrikson, R L; Kezdy, F J


    Pineapple stem acetone powder provides a rich source of the sulfhydryl protease bromelain and of a family of compositionally similar but chromatographically distinct polypeptide inihibtors of this enzyme. The isoinhibitors have molecular weights of 5600, and they contain five disulfide bonds and about 50 amino acids each (Perlstein, S. H., AND Kezdy, F.J. (1973) J. Supramol. Struct. 1, 249-254). Primary structural analysis of one of the seven inhibitor fractions (VII) revealed extensive microheterogeneity. Each of the inhibitor molecules in Fraction VII was shown to be composed of two peptide chains joined by disulfide bonds. These chains, designated A and B on the basis of size, comprise 41 and 10-11 residues, respectively, and the amino acid sequence of one of each are given below: (see article for formular). On the basis of ionization properties and yields of the A and B chains, it would appear that one of the major inhibitor species in Fraction VII is the covalently linked complex of the two chains shown, namely [A-1, B-2]. The second major inhibitor component of Fraction VII is identical in structure with [A-1, B-2i1 except that residues 1 and 8 in the A chain are pyroglutamate and threonine, respectively, and in the B chain glutamine 11 is replaced by arginine. The third inhibitor in Fraction VII is a minor constituent identical with the second, except that residue 1 in the A chain is glutamate rather than pyroglutamate. This microheterogeneity in the inhibitors of Fraction VII is further increased by the fact that B chains may lack threonine 1, in which case they are decapeptides beginning with alanine. On the basis of the striking homology of the cysteine residues with those of other protease inhibitors, it is proposed that the bromelain inhibitors are generated enzymatically from single chain precursors by excision of a "bridge" paptide which links the NH-2 termal A chain to the COOH-terminal B chain.

  7. A new hybrid coding for protein secondary structure prediction based on primary structure similarity.

    Li, Zhong; Wang, Jing; Zhang, Shunpu; Zhang, Qifeng; Wu, Wuming


    The coding pattern of protein can greatly affect the prediction accuracy of protein secondary structure. In this paper, a novel hybrid coding method based on the physicochemical properties of amino acids and tendency factors is proposed for the prediction of protein secondary structure. The principal component analysis (PCA) is first applied to the physicochemical properties of amino acids to construct a 3-bit-code, and then the 3 tendency factors of amino acids are calculated to generate another 3-bit-code. Two 3-bit-codes are fused to form a novel hybrid 6-bit-code. Furthermore, we make a geometry-based similarity comparison of the protein primary structure between the reference set and the test set before the secondary structure prediction. We finally use the support vector machine (SVM) to predict those amino acids which are not detected by the primary structure similarity comparison. Experimental results show that our method achieves a satisfactory improvement in accuracy in the prediction of protein secondary structure.

  8. Embrittlement and Flow Localization in Reactor Structural Materials

    Xianglin Wu; Xiao Pan; James Stubbins


    Many reactor components and structural members are made from metal alloys due, in large part, to their strength and ability to resist brittle fracture by plastic deformation. However, brittle fracture can occur when structural material cannot undergo extensive, or even limited, plastic deformation due to irradiation exposure. Certain irradiation conditions lead to the development of a damage microstructure where plastic flow is limited to very small volumes or regions of material, as opposed to the general plastic flow in unexposed materials. This process is referred to as flow localization or plastic instability. The true stress at the onset of necking is a constant regardless of the irradiation level. It is called 'critical stress' and this critical stress has strong temperature dependence. Interrupted tensile testes of 316L SS have been performed to investigate the microstructure evolution and competing mechanism between mechanic twinning and planar slip which are believed to be the controlling mechanism for flow localization. Deformation twinning is the major contribution of strain hardening and good ductility for low temperatures, and the activation of twinning system is determined by the critical twinning stress. Phases transform and texture analyses are also discussed in this study. Finite element analysis is carried out to complement the microstructural analysis and for the prediction of materaials performance with and without stress concentration and irradiation.

  9. Optical Flow Structure Effects in Children’s Postural Control

    Barela, José A.


    The aim of this study was to investigate the effect of distance and optic flow structure on visual information and body sway coupling in children and young adults. Thirty children (from 4 to 12 years of age) and 10 young adults stood upright inside of a moving room oscillating at 0.2 Hz, at 0.25 and 1.5 m from the front wall, and under three optical flow conditions (global, central, and peripheral). Effect of distance and optic flow structure on the coupling of visual information and body sway is age-dependent, with 4-year-olds being more affected at 0.25 m distance than older children and adults are. No such difference was observed at 1.5 m from the front wall. Moreover, 4-year-olds’ sway was larger and displayed higher variability. These results suggest that despite being able to accommodate change resulting from varying optic flow conditions, young children have difficulty in dodging stronger visual stimuli. Lastly, difference in sway performance may be due to immature inter-modality sensory reweighting. PMID:27352305

  10. Structure of the velocity gradient tensor in turbulent shear flows

    Pumir, Alain


    The expected universality of small-scale properties of turbulent flows implies isotropic properties of the velocity gradient tensor in the very large Reynolds number limit. Using direct numerical simulations, we determine the tensors formed by n =2 and 3 velocity gradients at a single point in turbulent homogeneous shear flows and in the log-layer of a turbulent channel flow, and we characterize the departure of these tensors from the corresponding isotropic prediction. Specifically, we separate the even components of the tensors, invariant under reflexion with respect to all axes, from the odd ones, which identically vanish in the absence of shear. Our results indicate that the largest deviation from isotropy comes from the odd component of the third velocity gradient correlation function, especially from the third moment of the derivative along the normal direction of the streamwise velocity component. At the Reynolds numbers considered (Reλ≈140 ), we observe that these second- and third-order correlation functions are significantly larger in turbulent channel flows than in homogeneous shear flow. Overall, our work demonstrates that a mean shear leads to relatively simple structure of the velocity gradient tensor. How isotropy is restored in the very large Reynolds limit remains to be understood.

  11. Subsurface magnetic field and flow structure of simulated sunspots

    Rempel, Matthias


    We present a series of numerical sunspot models addressing the subsurface field and flow structure in up to 16 Mm deep domains covering up to 2 days of temporal evolution. Changes in the photospheric appearance of the sunspots are driven by subsurface flows in several Mm depth. Most of magnetic field is pushed into a downflow vertex of the subsurface convection pattern, while some fraction of the flux separates from the main trunk of the spot. Flux separation in deeper layers is accompanied in the photosphere with light bridge formation in the early stages and formation of pores separating from the spot at later stages. Over a time scale of less than a day we see the development of a large scale flow pattern surrounding the sunspots, which is dominated by a radial outflow reaching about 50% of the convective rms velocity in amplitude. Several components of the large scale flow are found to be independent from the presence of a penumbra and the associated Evershed flow. While the simulated sunspots lead to blo...

  12. Cross flow response of a cylindrical structure under local shear flow

    Yoo-Chul Kim


    Full Text Available The VIV (Vortex-Induced Vibration analysis of a flexible cylindrical structure under locally strong shear flow is presented. The model is made of Teflon and has 9.5m length, 0.0127m diameter, and 0.001m wall thickness. 11 2-dimensional accelerometers are installed along the model. The experiment has been conducted at the ocean engineering basin in the University of Tokyo in which uniform current can be generated. The model is installed at about 30 degree of slope and submerged by almost overall length. Local shear flow is made by superposing uniform current and accelerated flow generated by an impeller. The results of frequency and modal analysis are presented.

  13. Origin of Permeability and Structure of Flows in Fractured Media

    De Dreuzy, J.; Darcel, C.; Davy, P.; Erhel, J.; Le Goc, R.; Maillot, J.; Meheust, Y.; Pichot, G.; Poirriez, B.


    After more than three decades of research, flows in fractured media have been shown to result from multi-scale geological structures. Flows result non-exclusively from the damage zone of the large faults, from the percolation within denser networks of smaller fractures, from the aperture heterogeneity within the fracture planes and from some remaining permeability within the matrix. While the effect of each of these causes has been studied independently, global assessments of the main determinisms is still needed. We propose a general approach to determine the geological structures responsible for flows, their permeability and their organization based on field data and numerical modeling [de Dreuzy et al., 2012b]. Multi-scale synthetic networks are reconstructed from field data and simplified mechanical modeling [Davy et al., 2010]. High-performance numerical methods are developed to comply with the specificities of the geometry and physical properties of the fractured media [Pichot et al., 2010; Pichot et al., 2012]. And, based on a large Monte-Carlo sampling, we determine the key determinisms of fractured permeability and flows (Figure). We illustrate our approach on the respective influence of fracture apertures and fracture correlation patterns at large scale. We show the potential role of fracture intersections, so far overlooked between the fracture and the network scales. We also demonstrate how fracture correlations reduce the bulk fracture permeability. Using this analysis, we highlight the need for more specific in-situ characterization of fracture flow structures. Fracture modeling and characterization are necessary to meet the new requirements of a growing number of applications where fractures appear both as potential advantages to enhance permeability and drawbacks for safety, e.g. in energy storage, stimulated geothermal energy and non-conventional gas productions. References Davy, P., et al. (2010), A likely universal model of fracture scaling and

  14. Lagrangian structures in time-periodic vortical flows

    S. V. Kostrykin


    Full Text Available The Lagrangian trajectories of fluid particles are experimentally studied in an oscillating four-vortex velocity field. The oscillations occur due to a loss of stability of a steady flow and result in a regular reclosure of streamlines between the vortices of the same sign. The Eulerian velocity field is visualized by tracer displacements over a short time period. The obtained data on tracer motions during a number of oscillation periods show that the Lagrangian trajectories form quasi-regular structures. The destruction of these structures is determined by two characteristic time scales: the tracers are redistributed sufficiently fast between the vortices of the same sign and much more slowly transported into the vortices of opposite sign. The observed behavior of the Lagrangian trajectories is quantitatively reproduced in a new numerical experiment with two-dimensional model of the velocity field with a small number of spatial harmonics. A qualitative interpretation of phenomena observed on the basis of the theory of adiabatic chaos in the Hamiltonian systems is given. The Lagrangian trajectories are numerically simulated under varying flow parameters. It is shown that the spatial-temporal characteristics of the Lagrangian structures depend on the properties of temporal change in the streamlines topology and on the adiabatic parameter corresponding to the flow. The condition for the occurrence of traps (the regions where the Lagrangian particles reside for a long time is obtained.

  15. Structure of urban movements: polycentric activity and entangled hierarchical flows.

    Camille Roth

    Full Text Available The spatial arrangement of urban hubs and centers and how individuals interact with these centers is a crucial problem with many applications ranging from urban planning to epidemiology. We utilize here in an unprecedented manner the large scale, real-time 'Oyster' card database of individual person movements in the London subway to reveal the structure and organization of the city. We show that patterns of intraurban movement are strongly heterogeneous in terms of volume, but not in terms of distance travelled, and that there is a polycentric structure composed of large flows organized around a limited number of activity centers. For smaller flows, the pattern of connections becomes richer and more complex and is not strictly hierarchical since it mixes different levels consisting of different orders of magnitude. This new understanding can shed light on the impact of new urban projects on the evolution of the polycentric configuration of a city and the dense structure of its centers and it provides an initial approach to modeling flows in an urban system.

  16. Effect of primary jet geometry on ejector performance: A cold-flow investigation

    Zare-Behtash, H.; Gongora-Orozco, N. [School of MACE, University of Manchester, M60 1QD (United Kingdom); Kontis, K., E-mail: [School of MACE, University of Manchester, M60 1QD (United Kingdom)


    Graphical abstract: Research Highlights: > Using a shock tube the performance of an air-ejector is examined. > Varying the shock tube geometry changes the performance of the ejector. > Shock waves reflected from the ejector inlet effect its efficacy. > In some instances flow separation occurs at the ejector inlet creating a vortex ring. > Circular shock tube creates the highest ejector impulse compared to other shapes. - Abstract: The following cold-flow study examines the interaction of the diffracted shock wave pattern and the resulting vortex loop emitted from a shock tube of various geometries, with an ejector having a round bell-shaped inlet. The focus of the study is to examine the performance of the ejector when using different jet geometries (primary flow) to entrain secondary flow through the ejector. These include two circular nozzles with internal diameters of 15 mm and 30 mm, two elliptical nozzles with minor to major axis ratios of a/b = 0.4 and 0.6 with b = 30 mm, a square nozzle with side lengths of 30 mm, and two exotic nozzles resembling a pair of lips with axis ratios of a/b = 0.2 and 0.5 with b = 30 mm. Shock tube driver pressures of P{sub 4} = 4, 8, and 12 bar were studied, with the pressure of the shock tube driven section P{sub 1} being atmospheric. High-speed schlieren photography using the Shimadzu Hypervision camera along with detailed pressure measurements along the ejector and the impulse created by the ejector were conducted.


    HUA Zu-lin; GU Li; CHU Ke-jian


    The braided river is a typical river pattern in nature, but there is a paucity of comprehensive data set describing the three-dimensional flow field in the braided river. A physical model experiment was used to study the flow characteristics in the typical braided river with a mid-bar between two anabranches. In the experiment, two kinds of mid-bar with the ratios of its length to maximal width of 3 and 5 were considered. Moreover, the mid-bar could be moved to adjust the width of two anabranches. The detailed measurements of velocity were conducted using an acoustic Doppler velocimeter over a grid defined throughout the whole braided river region, including the bifurcation, two anabranches and the confluence. In two kinds of mid-bar braided models, a separation zone was observed in the anabranch of the model in which the ratio of length to maximal width of mid-bar is 3, however the separation zone was not found in another model in which the ratio is 5. In addition, the opposite secondary cells were observed at the bend apex of anabranch in two models, and different longitudinal velocity distributions in the entrance region of anabranch account for this opposite flow structure. Finally, turbulent kinetic energy were shown and compared in different situations. The high turbulence occurs at the place with strong shear, especially at the boundary of the separation zone and the high velocity passing flow.

  18. Configuration of Self-consistent Flows in a Hole Structure

    Hasegawa, Hiroki; Ishiguro, Seiji


    Self-consistent particle flows in a hole structure have been studied with a three dimensional electrostatic plasma particle simulation code. In our previous study, we investigated kinetic effects on plasma blob dynamics with the particle simulation code. In this study, we have improved the code in order to investigate the hole propagation dynamics. Here, the hole is the intermittent filamentary structure along the magnetic field line in peripheral plasmas of fusion magnetic confinement devices and the plasma density in the hole is lower than that of background plasma. In the simulation, a hole structure is initially set as a cylindrical form elongated between both end plates and propagates in the grad-B direction. The simulation confirms that a spiral current system is formed in a hole structure. Further, the investigation into the effect of impurities on the flow configuration will be reported. Supported by NIFS Collaboration Research programs (NIFS15KNSS058, NIFS14KNXN279, NIFS15KNTS039, NIFS15KNTS040, and NIFS16KNTT038).

  19. Coherent Turbulent Flow Structures in a Gravel-Bed River

    Ashley, W.; Macmahan, J. H.; Reniers, A. J.; Thornton, E. B.; Brown, J.; Swick, W. A.


    The characteristics of coherent turbulent flow structures were examined during multi-day deployments with three different sensors in a gravel-bed river reach section of the Kootenai River, ID in August 2010. In-situ river velocities were measured using a custom 2 MHz Acoustic Doppler Current Profiler (ADCP) head, an Acoustic Doppler Velocimeter (ADV), and a lagged array of six electromagnetic current meters (ECM) mounted on a GPS-equipped portable aluminum frame. The frame was deployed in the river which varied from 0.6 to 1m water depths and 0.5 to 1.5 m/s velocities. It was also deployed in a small channel, near riffle pools, and on the lee of river obstructions. The ECM array was horizontally mounted on a 4m length pole attached to the frame, oriented in the stream-wise direction, with a sampling frequency of 16 Hz. The lagged spacing of the six ECMs was set to resolve coherent motions from up to 8m in length. The ADCP was fitted with a custom head to measure the along beam velocities in all three axes, with a sampling frequency of 1 Hz, 35cm bins, with a maximum range of 10m. The upstream beam is used to describe the coherent structures in the stream-wise velocity. An iterative maximum likelihood estimator is used to evaluate the streamwise wavenumber-frequency spectrum. The coherent structures measured by the ECM array and ADCP are compared to validate the results by the new ADCP head. Turbulent measurements from the 32 Hz sampled ADV are compared to the ADCP and ECM. Our unique approach provides spatial measurements in river reaches (depths) previously not examined. The flow structure as a function of river feature, bed roughness, and flow velocity are described in the stream-wise and lateral directions. This effort was supported by the Office of Naval Research Coastal Geosciences Program.

  20. Coherent structures and extreme events in rotating multiphase turbulent flows

    Biferale, Luca; Mazzitelli, Irene M; van Hinsberg, Michel A T; Lanotte, Alessandra S; Musacchio, Stefano; Perlekar, Prasad; Toschi, Federico


    By using direct numerical simulations (DNS) at unprecedented resolution we study turbulence under rotation in the presence of simultaneous direct and inverse cascades. The accumulation of energy at large scale leads to the formation of vertical coherent regions with high vorticity oriented along the rotation axis. By seeding the flow with millions of inertial particles, we quantify -for the first time- the effects of those coherent vertical structures on the preferential concentration of light and heavy particles. Furthermore, we quantitatively show that extreme fluctuations, leading to deviations from a normal-distributed statistics, result from the entangled interaction of the vertical structures with the turbulent background. Finally, we present the first-ever measurement of the relative importance between Stokes drag, Coriolis force and centripetal forces along the trajectories of inertial particles. We discover that vortical coherent structures lead to unexpected diffusion properties for heavy and light ...

  1. Coherent Structures and Extreme Events in Rotating Multiphase Turbulent Flows

    L. Biferale


    Full Text Available By using direct numerical simulations (DNS at unprecedented resolution, we study turbulence under rotation in the presence of simultaneous direct and inverse cascades. The accumulation of energy at large scale leads to the formation of vertical coherent regions with high vorticity oriented along the rotation axis. By seeding the flow with millions of inertial particles, we quantify—for the first time—the effects of those coherent vertical structures on the preferential concentration of light and heavy particles. Furthermore, we quantitatively show that extreme fluctuations, leading to deviations from a normal-distributed statistics, result from the entangled interaction of the vertical structures with the turbulent background. Finally, we present the first-ever measurement of the relative importance between Stokes drag, Coriolis force, and centripetal force along the trajectories of inertial particles. We discover that vortical coherent structures lead to unexpected diffusion properties for heavy and light particles in the directions parallel and perpendicular to the rotation axis.

  2. Coherent Structures and Extreme Events in Rotating Multiphase Turbulent Flows

    Biferale, L.; Bonaccorso, F.; Mazzitelli, I. M.; van Hinsberg, M. A. T.; Lanotte, A. S.; Musacchio, S.; Perlekar, P.; Toschi, F.


    By using direct numerical simulations (DNS) at unprecedented resolution, we study turbulence under rotation in the presence of simultaneous direct and inverse cascades. The accumulation of energy at large scale leads to the formation of vertical coherent regions with high vorticity oriented along the rotation axis. By seeding the flow with millions of inertial particles, we quantify—for the first time—the effects of those coherent vertical structures on the preferential concentration of light and heavy particles. Furthermore, we quantitatively show that extreme fluctuations, leading to deviations from a normal-distributed statistics, result from the entangled interaction of the vertical structures with the turbulent background. Finally, we present the first-ever measurement of the relative importance between Stokes drag, Coriolis force, and centripetal force along the trajectories of inertial particles. We discover that vortical coherent structures lead to unexpected diffusion properties for heavy and light particles in the directions parallel and perpendicular to the rotation axis.

  3. Social dilemma structure hidden behind traffic flow with route selection

    Tanimoto, Jun; Nakamura, Kousuke


    Several traffic flows contain social dilemma structures. Herein, we explored a route-selection problem using a cellular automaton simulation dovetailed with evolutionary game theory. In our model, two classes of driver-agents coexist: D agents (defective strategy), which refer to traffic information for route selection to move fast, and C agents (cooperative strategy), which are insensitive to information and less inclined to move fast. Although no evidence suggests that the social dilemma structure in low density causes vehicles to move freely and that in high density causes traffic jams, we found a structure that corresponds to an n-person (multiplayer) Chicken (n-Chicken) game if the provided traffic information is inappropriate. If appropriate traffic information is given to the agents, the n-Chicken game can be solved. The information delivered to vehicles is crucial for easing the social dilemma due to urban traffic congestion when developing technologies to support the intelligent transportation system (ITS).

  4. Turbulent rotating plane Couette flow: Reynolds and rotation number dependency of flow structure and momentum transport

    Kawata, Takuya; Alfredsson, P. Henrik


    Plane Couette flow under spanwise, anticyclonic system rotation [rotating plane Couette flow (RPCF)] is studied experimentally using stereoscopic particle image velocimetry for different Reynolds and rotation numbers in the fully turbulent regime. Similar to the laminar regime, the turbulent flow in RPCF is characterized by roll cells, however both instantaneous snapshots of the velocity field and space correlations show that the roll cell structure varies with the rotation number. All three velocity components are measured and both the mean flow and all four nonzero Reynolds stresses are obtained across the central parts of the channel. This also allows us to determine the wall shear stress from the viscous stress and the Reynolds stress in the center of the channel, and for low rotation rates the wall shear stress increases with increasing rotation rate as expected. The results show that zero absolute vorticity is established in the central parts of the channel of turbulent RPCF for high enough rotation rates, but also that the mean velocity profile for certain parameter ranges shows an S shape giving rise to a negative velocity gradient in the center of the channel. We find that from an analysis of the Reynolds stress transport equation using the present data there is a transport of the Reynolds shear stress towards the center of the channel, which may then result in a negative mean velocity gradient there.

  5. Measurements of the tip-gap turbulent flow structure in a low-speed compressor cascade

    Tang, Genglin

    This dissertation presents results from a thorough study of the tip-gap turbulent flow structure in a low-speed linear compressor cascade wind tunnel at Virginia Tech that includes a moving belt system to simulate the relative motion between the tip and the casing. The endwall pressure measurements and the surface oil flow visualizations were made on a stationary endwall to obtain the flow features and to determine the measurement profiles of interest. A custom-made miniature 3-orthogonal-velocity-component fiber-optic laser-Doppler velocimetry (LDV) system was used to measure all three components of velocity within a 50 mum spherical measurement volume within the gap between the endwall and the blade tip, mainly for the stationary wall with 1.65% and 3.30% tip gaps as well as some initial experiments for the moving wall. Since all of the vorticity in a flow originates from the surfaces under the action of strong pressure gradient, it was very important to measure the nearest-wall flow on the endwall and around the blade tip. The surface skin friction velocity was measured by using viscous sublayer velocity profiles, which verified the presence of an intense lateral shear layer that was observed from surface oil flow visualizations. All second- and third-order turbulence quantities were measured to provide detailed data for any parallel CFD efforts. The most complete data sets were acquired for 1.65% and 3.30% tip gap/chord ratios in a low-speed linear compressor cascade. This study found that tip gap flows are complex pressure-driven, unsteady three-dimensional turbulent flows. The crossflow velocity normal to the blade chord is nearly uniform in the and tip-gap and changes substantially from the pressure to suction side. The crossflow velocity relies on the local tip pressure loading that is different from the mid-span pressure loading because of tip leakage vortex influence. The tip gap flow is highly skewed three-dimensional flow throughout the full gap

  6. Structure of a poly(ethylene) opposed flow diffusion flame

    Pitz, W.J.; Brown, N.J.; Sawyer, R.F.


    Structural measurements were obtained and compared with other investigations of diffusion flames. Departures from the commonly assumed collapsed flame model of laminar diffusion flames were observed in terms of excessive CO concentrations and oxygen penetration into the fuel side of the flame. An upper bound on the importance of oxygen diffusion to the fuel surface and subsequent surface oxidation was placed at 20% of the energy required for fuel pyrolysis, with the remainder of the energy being delivered to the surface from the flame through heat transfer processes. As the oxygen concentration in the oxidizer flow was decreased and extinction conditions approached, the CO/CO/sub 2/ ratio at the flame increased slightly, the oxygen concentration at the luminous flame zone decreased, the flame stand-off distance decreased, and the flame temperature decreased. Radial similarity in the composition and temperature profiles was established experimentally which confirms predictions and greatly simplifies the modeling of the opposed flow diffusion flame.

  7. Stability of Brillouin Flow in Slow-Wave Structures

    Simon, David; Lau, Y. Y.; Greening, Geoffrey; Wong, Patrick; Gilgenbach, Ronald; Hoff, Brad


    For the first time, we include a slow-wave structure (SWS) to study the stability of Brillouin flow in the conventional, planar, and inverted magnetron geometry. The resonant interaction of the SWS circuit mode and the corresponding smooth-bore diocotron-like mode is found to be the dominant cause for instability, overwhelming the intrinsic negative (positive) mass property of electrons in the inverted (conventional) magnetron geometry. It severely restricts the wavenumber for instability to the narrow range in which the cold tube frequency of the SWS is within a few percent of the corresponding smooth bore diocotron-like mode in the Brillouin flow. This resonant interaction is absent in a smooth bore magnetron. Work supported by ONR N00014-13-1-0566 and N00014-16-1-2353, AFOSR FA9550-15-1-0097, and L-3 Communications Electron Device Division.

  8. A Few Expanding Integrable Models, Hamiltonian Structures and Constrained Flows

    ZHANG Yu-Feng


    Two kinds of higher-dimensional Lie algebras and their loop algebras are introduced, for which a few expanding integrable models including the coupling integrable couplings of the Broer-Kaup (BK) hierarchy and the dispersive long wave (DLW) hierarchy as well as the TB hierarchy are obtained.From the reductions of the coupling integrable couplings, the corresponding coupled integrable couplings of the BK equation, the DLW equation, and the TB equation are obtained, respectively.Especially, the coupling integrable coupling of the TB equation reduces to a few integrable couplings of the well-known mKdV equation.The Hamiltonian structures of the coupling integrable couplings of the three kinds of soliton hierarchies are worked out, respectively, by employing the variational identity.Finally,we decompose the BK hierarchy of evolution equations into x-constrained flows and tn-constrained flows whose adjoint representations and the Lax pairs are given.

  9. Improving Ambient Wind Environments of a Cross-flow Wind Turbine near a Structure by using an Inlet Guide Structure and a Flow Deflector

    Tadakazu TANINO; Shinichiro NAKAO; Genki UEBAYASHI


    A cross-flow wind turbine near a structure was tested for the performance. The results showed that the performance of a cross-flow wind turbine near a structure was up to 30% higher than the one without a structure.In addition, we tried to get higher performance of a cross-flow wind turbine by using an Inlet Guide Structure and a Flow Deflector. An Inlet Guide Structure was placed on the edge of a structure and a Flow Deflector was set near a cross-flow wind turbine and can improve ambient wind environments of the wind turbine, the maximum power coefficients were about 15 to 40% higher and the tip speed ratio range showing the high power coefficient was wide and the positive gradients were steep apparently.

  10. Turbulent flow in a ribbed channel: Flow structures in the vicinity of a rib

    Wang, Lei; Salewski, Mirko; Sundén, Bengt


    PIV measurements are performed in a channel with periodic ribs on one wall. The emphasis of this study is to investigate the flow structures in the vicinity of a rib in terms of mean velocities, Reynolds stresses, probability density functions (PDF), and two-point correlations. The PDF distribution...... of u′ is bimodal in the separated shear layer downstream of the rib. The maximum Reynolds shear stresses occur at the leading edge of the rib. Based on quadrant analysis, it is found that ejection motions make a dominant contribution to the Reynolds shear stress in this region. Moreover, topology......-based visualization is applied to the separation bubble upstream of the rib. Salient critical points and limit cycles are extracted, which gives clues to the physical processes occurring in the flow....

  11. Coherent structure coloring: identification of coherent structures from sparse flow trajectories using graph theory

    Schlueter, Kristy; Dabiri, John


    Coherent structure identification is important in many fluid dynamics applications, including transport phenomena in ocean flows and mixing and diffusion in turbulence. However, many of the techniques currently available for measuring such flows, including ocean drifter datasets and particle tracking velocimetry, only result in sparse velocity data. This is often insufficient for the use of current coherent structure detection algorithms based on analysis of the deformation gradient. Here, we present a frame-invariant method for detecting coherent structures from Lagrangian flow trajectories that can be sparse in number. The method, based on principles used in graph coloring algorithms, examines a measure of the kinematic dissimilarity of all pairs of flow trajectories, either measured experimentally, e.g. using particle tracking velocimetry; or numerically, by advecting fluid particles in the Eulerian velocity field. Coherence is assigned to groups of particles whose kinematics remain similar throughout the time interval for which trajectory data is available, regardless of their physical proximity to one another. Through the use of several analytical and experimental validation cases, this algorithm is shown to robustly detect coherent structures using significantly less flow data than is required by existing methods. This research was supported by the Department of Defense (DoD) through the National Defense Science & Engineering Graduate Fellowship (NDSEG) Program.

  12. Effects of flow intermittency and pharmaceutical exposure on the structure and metabolism of stream biofilms.

    Corcoll, Natàlia; Casellas, Maria; Huerta, Belinda; Guasch, Helena; Acuña, Vicenç; Rodríguez-Mozaz, Sara; Serra-Compte, Albert; Barceló, Damià; Sabater, Sergi


    Increasing concentrations of pharmaceutical compounds occur in many rivers, but their environmental risk remains poorly studied in stream biofilms. Flow intermittency shapes the structure and functions of ecosystems, and may enhance their sensitivity to toxicants. This study evaluates the effects of a long-term exposure of biofilm communities to a mixture of pharmaceutical compounds at environmental concentrations on biofilm bioaccumulation capacity, the structure and metabolic processes of algae and bacteria communities, and how their potential effects were enhanced or not by the occurrence of flow intermittency. To assess the interaction between those two stressors, an experiment with artificial streams was performed. Stream biofilms were exposed to a mixture of pharmaceuticals, as well as to a short period of flow intermittency. Results indicate that biofilms were negatively affected by pharmaceuticals. The algal biomass and taxa richness decreased and unicellular green algae relatively increased. The structure of the bacterial (based on denaturing gradient gel electrophoresis of amplified 16S rRNA genes) changed and showed a reduction of the operational taxonomic units (OTUs) richness. Exposed biofilms showed higher rates of metabolic processes, such as primary production and community respiration, attributed to pharmaceuticals stimulated an increase of green algae and heterotrophs, respectively. Flow intermittency modulated the effects of chemicals on natural communities. The algal community became more sensitive to short-term exposure of pharmaceuticals (lower EC50 value) when exposed to water intermittency, indicating cumulative effects between the two assessed stressors. In contrast to algae, the bacterial community became less sensitive to short-term exposure of pharmaceuticals (higher EC50) when exposed to water intermittency, indicating co-tolerance phenomena. According to the observed effects, the environmental risk of pharmaceuticals in nature is high

  13. Bottlenecks to vibrational energy flow in OCS: Structures and mechanisms

    Paškauskas, R; Uzer, T


    Finding the causes for the nonstatistical vibrational energy relaxation in the planar carbonyl sulfide (OCS) molecule is a longstanding problem in chemical physics: Not only is the relaxation incomplete long past the predicted statistical relaxation time, but it also consists of a sequence of abrupt transitions between long-lived regions of localized energy modes. We report on the phase space bottlenecks responsible for this slow and uneven vibrational energy flow in this Hamiltonian system with three degrees of freedom. They belong to a particular class of two-dimensional invariant tori which are organized around elliptic periodic orbits. We relate the trapping and transition mechanisms with the linear stability of these structures.

  14. Optical flow with structure information for epithelial image mosaicing.

    Ali, Sharib; Faraz, Khuram; Daul, Christian; Blondel, Walter


    Mosaicing of biological tissue surfaces is challenging due to the weak image textures. This contribution presents a mosaicing algorithm based on a robust and accurate variational optical flow scheme. A Riesz pyramid based multiscale approach aims at overcoming the "flattening-out" problem at coarser levels. Moreover, the structure information present in images of epithelial surfaces is incorporated into the data-term to improve the algorithm robustness. The algorithm accuracy is first assessed with simulated sequences and then used for mosaicing standard clinical endoscopic data.

  15. Misunderstanding and Understanding of Primary Water Stress Corrosion Cracking of Structural Components in the Primary System of PWRs

    Kim, Young Suk; Kim, Sung Soo; Kim, Dae Whan [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)


    All the structural components in the primary system of pressurized water reactors that are in contact with primary water are made of austenitic Ni-Cr-Fe alloys which are known to be corrosion resistant. Nevertheless, these Ni-Cr-Fe alloys such as Alloy 600, weld 182/82, austenitic stainless steels suffer from intergranular stress corrosion cracking (IGSCC) after their 10 year operation in reactors although the environment to which they have been exposed is almost pure water of pH 6.9 to 7.2, which is called primary water stress corrosion cracking (PWSCC). Given that the underlying mechanism of PWSCC remains unidentified so far, there are many misunderstandings related to PWSCC of the structural components, which may lead to unreasonable mitigation measures. The aim of this work is to highlight understanding and misunderstanding of PWSCC related to austenitic Ni-Cr-Fe alloys.

  16. Primary structure of human alpha 2-macroglobulin. V. The complete structure

    Sottrup-Jensen, Lars; Stepanik, Terrence M; Kristensen, Torsten


    The primary structure of the tetrameric plasma glycoprotein human alpha 2-macroglobulin has been determined. The identical subunits contain 1451 amino acid residues. Glucosamine-based oligosaccharide groups are attached to asparagine residues 32, 47, 224, 373, 387, 846, 968, and 1401. Eleven...... in the activation cleavage area (the "bait" region) are located in the sequence: -Arg681-Val-Gly-Phe-Tyr-Glu-. The molecular weight of the unmodified alpha 2-macroglobulin subunit is 160,837 and approximately 179,000, including the carbohydrate groups. The presence of possible internal homologies within the alpha 2...

  17. Analysis on three-dimensional flow and heat transfer in a cross wavy primary surface recuperator for a microturbine system

    Gui Xiaohong


    Full Text Available In this paper, three-dimensional periodic numerical model for fully developed flow in a cross wavy primary surface recuperator for a microturbine system is built. The performance of flow and heat transfer is analyzed. The fields of flow and temperature in a gas and air channel are obtained. Different working conditions are numerically simulated. Numerical results are compared with experimental data concerned. Analysis results show that the flow in the gas and air channel is anti-symmetry along the centre of channel. The flow of fluid is fluctuant. The flow velocity of gas is much higher than that of air. The thermal ratio of cross wavy primary surface recuperator can reach 95.2%. The thermal ratio decreases with the improvement of gas inlet temperature. When gas inlet temperature increases by 100 K, the thermal ratio decreases by about 1%. The thermal ratio increases with the reduction of flow rate in the channel. When flow rate reduces by 40%, the thermal ratio increases by about 4%. The research results can be used to guide checking the performance of a recuperator.

  18. Extraction of coherent structures in a rotating turbulent flow experiment

    Ruppert-Felsot, J E; Sharon, E; Swinney, H L; Ruppert-Felsot, Jori E.; Praud, Olivier; Sharon, Eran; Swinney, Harry L.


    The discrete wavelet packet transform (DWPT) and discrete wavelet transform (DWT) are used to extract and study the dynamics of coherent structures in a turbulent rotating fluid. Three-dimensional (3D) turbulence is generated by strong pumping through tubes at the bottom of a rotating tank (48.4 cm high, 39.4 cm diameter). This flow evolves toward two-dimensional (2D) turbulence with increasing height in the tank. Particle Image Velocimetry (PIV) measurements on the quasi-2D flow reveal many long-lived coherent vortices with a wide range of sizes. The vorticity fields exhibit vortex birth, merger, scattering, and destruction. We separate the flow into a low-entropy ``coherent'' and a high-entropy ``incoherent'' component by thresholding the coefficients of the DWPT and DWT of the vorticity fields. Similar thresholdings using the Fourier transform and JPEG compression together with the Okubo-Weiss criterion are also tested for comparison. We find that the DWPT and DWT yield similar results and are much more ef...

  19. Ion flow and sheath structure near positively biased electrodes

    Hood, R.; Scheiner, B.; Baalrud, S. D.; Hopkins, M. M.; Barnat, E. V.; Yee, B. T.; Merlino, R. L.; Skiff, F.


    What effect does a dielectric material surrounding a small positively biased electrode have on the ion flow and sheath structure near the electrode? Measurements of the ion velocity distribution function and plasma potential near positively biased electrodes were made using laser-induced fluorescence and an emissive probe. The results were compared with 2D particle-in-cell simulations. Both measurements and simulations showed that when the positive electrode was surrounded by the dielectric material, ions were accelerated toward the electrode to approximately 0.5 times the ion sound speed before being deflected radially by the electron sheath potential barrier of the electrode. The axial potential profile in this case contained a virtual cathode. In comparison, when the dielectric material was removed from around the electrode, both the ion flow and virtual cathode depth near the electrode were dramatically reduced. These measurements suggest that the ion presheath from the dielectric material surrounding the electrode may enclose the electron sheath of the electrode, resulting in a virtual cathode that substantially influences the ion flow profile in the region.

  20. CFD simulations of flow erosion and flow-induced deformation of needle valve: Effects of operation, structure and fluid parameters

    Zhu, Hongjun, E-mail: [State Key Laboratory of Oil and Gas Reservoir Geology and Exploitation, Southwest Petroleum University, Chengdu 610500, Sichuan (China); State Key Laboratory of Hydraulics and Mountain River Engineering, Sichuan University, Chengdu 610065, Sichuan (China); Pan, Qian; Zhang, Wenli; Feng, Guang; Li, Xue [State Key Laboratory of Oil and Gas Reservoir Geology and Exploitation, Southwest Petroleum University, Chengdu 610500, Sichuan (China)


    Highlights: • A combined FSI–CFD and DPM computational method is used to investigate flow erosion and deformation of needle valve. • The numerical model is validated with the comparison of measured and predicted erosion rate. • Effects of operation, structure and fluid parameters on flow erosion and flow-induced deformation are discussed. • Particle diameter has the most significant effect on flow erosion. • Inlet rate has the most obvious effect on flow-induced deformation. - Abstract: A three-dimensional fluid–structure interaction (FSI) computational model coupling with a combined continuum and discrete model has been used to predict the flow erosion rate and flow-induced deformation of needle valve. Comparisons with measured data demonstrate good agreement with the predictions of erosion rate. The flow field distribution of gas-particle flow and the erosion rate and deformation of valve core are captured under different operating and structural conditions with different fluid parameters. The effects of inlet velocity, valve opening and inlet valve channel size, particle concentration, particle diameter and particle phase components are discussed in detail. The results indicate that valve tip has the most severe erosion and deformation, and flow field, erosion rate and deformation of valve are all sensitive to inlet condition changes, structural changes and fluid properties changes. The effect of particle diameter on erosion is the most significant, while the influence of inlet rate on deformation is the greatest one.

  1. Structure identification in pipe flow using proper orthogonal decomposition

    Hellström, Leo H. O.; Smits, Alexander J.


    The energetic motions in direct numerical simulations of turbulent pipe flow at Reτ=685 are investigated using proper orthogonal decomposition. The procedure is extended such that a pressure component is identified in addition to the three-component velocity field for each mode. The pressure component of the modes is shown to align with the streamwise velocity component associated with the large-scale motions, where positive pressure coincides with positive streamwise velocity, and vice versa. The streamwise evolution of structures is then visualized using a conditional mode, which exhibit a strong similarity to the large-scale, low-momentum motions. A low-pressure region is present in the downstream section of the structure, and a high-pressure region is present in the upstream section.

  2. Structural Dynamics of Education Reforms and Quality of Primary Education in Uganda

    Nyenje, Aida


    This paper examines Uganda's recent undertaking to reform her Primary School education System with a focus on the effect of structural dynamics of education reforms and the quality of primary education. Structural dynamics in the context of this study is in reference to the organizational composition of the education system at the government,…

  3. The European Primary Care Monitor: structure, process and outcome indicators.

    Kringos, D.S.; Boerma, W.G.W.; Bourgueil, Y.; Cartier, T.; Hasvold, T.; Hutchinson, A.; Lember, M.; Oleszczyk, M.; Pavlick, D.R.; Svab, I.; Tedeschi, P.; Wilson, A.; Windak, A.


    Background:Scientific research has provided evidence on benefits of well developed primary care systems. The relevance of some of this research for the European situation is limited. There is currently a lack of up to date comprehensive and comparable information on variation in development of prima

  4. Primary Nocturnal Enuresis: A Structural and Strategic Family Systems Approach.

    Fletcher, Teresa B.


    Exploration of the literature regarding primary nocturnal enuresis suggests there are various causes including genetic, biological, physiological, and psychological explanations. Treatments typically consist of medication and behavioral intervention. However, it was believed that this enuretic case was caused by psychological trauma. A series of…

  5. Numerical and Experimental Study of the Flow Field Structure Evolution in the Circular Recess of Oil Cavity

    Feng Shen


    Full Text Available The laminar radial flow in the oil cavity of heavy-duty computer numerical control (CNC machines is very complicated and has not been fully explored. Navier-Stokes equations have been applied through the whole flow region using finite volume approach to explore this complicated flow phenomenon, including the influences of the clearance height (h, inlet nozzle Reynolds number (Re, and geometrical aspect ratio (e on flow behaviors. A fluid dynamic experiment has been conducted to study the flow structure by using particle image velocimetry (PIV. Numerical simulation results have been compared with the experimental results, finding a good agreement with the studied cases. The results suggest that there are complex vortices in the oil cavity. Flow field structure of the oil cavity largely depends on h, Re, and e. Re and e have a great influence on the size and amount of vortices, and h has slight effects on the size of the vortices. The lengths of primary, secondary, and tertiary isolated vortices have a linear relationship with h. The lengths of the primary and secondary isolated vortices increase linearly with ascending e as e is small. But when Re and e are large enough, the size of the three vortices decreases.

  6. Numerical and Experimental Investigation of Flow Structures During Insect Flight

    Badrya, Camli; Baeder, James D.


    Insect flight kinematics involves complex interplay between aerodynamics structural response and insect body control. Features such as cross-coupling kinematics, high flapping frequencies and geometrical small-scales, result in experiments being challenging to perform. In this study OVERTURNS, an in-house 3D compressible Navier-Stokes solver is utilized to simulate the simplified kinematics of an insect wing in hover and forward flight. The flapping wings simulate the full cycle of wing motion, i.e., the upstroke, downstroke, pronation and supination.The numerical results show good agreement against experimental data in predicting the lift and drag over the flapping cycle. The flow structures around the flapping wing are found to be highly unsteady and vortical. Aside from the tip vortex on the wings, the formation of a prominent leading edge vortex (LEV) during the up/down stroke portions, and the shedding of a trailing edge vortex (TEV) at end of each stroke were observed. Differences in the insect dynamics and the flow features of the LEV are observed between hover and forward flight. In hover the up and downstroke cycles are symmetric, whereas in forward flight, these up and downstroke are asymmetric and LEV strength varies as a function of the kinematics and advance ratio. This work was supported by the Micro Autonomous Systems and Technology (MAST) CTA at the Univer- sity of Maryland.

  7. Direct numerical simulation of Taylor-Couette flow with grooved walls: torque scaling and flow structure

    Zhu, Xiaojue; Verzicco, Roberto; Lohse, Detlef


    We present direct numerical simulations of Taylor-Couette flow with grooved walls at a fixed radius ratio $\\eta=r_i/r_o=0.714$ with inner cylinder Reynolds number up to $Re_i=3.76\\times10^4$, corresponding to Taylor number up to $Ta=2.15\\times10^9$. The grooves are axisymmetric V-shaped obstacles attached to the wall with a tip angle of $90^\\circ$. Results are compared with the smooth wall case in order to investigate the effects of grooves on Taylor-Couette flow. We focus on the effective scaling laws for the torque, flow structures, and boundary layers. It is found that, when the groove height is smaller than the boundary layer thickness, the torque is the same as that of the smooth wall cases. With increasing $Ta$, the boundary layer thickness becomes smaller than the groove height. Plumes are ejected from tips of the grooves and a secondary circulation between the latter is formed. This is associated to a sharp increase of the torque and thus the effective scaling law for the torque vs. $Ta$ becomes much ...

  8. Turbulent spots in channel flow: an experimental study Large-scale flow, inner structure and low order model

    Lemoult, Grégoire; Aider, Jean-Luc; Wesfreid, José Eduardo


    We present new experimental results on the development of turbulent spots in channel flow. The internal structure of a turbulent spot is measured, with Time Resolved Stereoscopic Particle Image Velocimetry. We report the observation of travelling-wave-like structures at the trailing edge of the turbulent spot. Special attention is paid to the large-scale flow surrounding the spot. We show that this large-scale flow is an asymmetric quadrupole centred on the spot. We measure the time evolution of the turbulent fluctuations and the mean flow distortions and compare these with the predictions of a nonlinear reduced order model predicting the main features of subcritical transition to turbulence.

  9. Three dimensional calculations of the primary coolant flow in a 900 MW PWR vessel. Numerical simulation of the accurate RCP start-up flow rate

    Martin, A.; Alvarez, D.; Cases, F.; Stelletta, S. [Electricite de France (EDF), 78 - Chatou (France). Lab. National d`Hydraulique


    This report explains the last results about the mixing in the 900 MW PWR vessels. The accurate fluid flow transient, induced by the RCP starting-up, is represented. In a first time, we present the Thermalhydraulic Finite Element Code N3S used for the 3D numerical computations. After that, results obtained for one reactor operation case are given. This case is dealing with the transient mixing of a clear plug in the vessel when one primary pump starts-up. A comparison made between two injection modes; a steady state fluid flow conditions or the accurate RCP transient fluid flow conditions. The results giving the local minimum of concentration and the time response of the mean concentration at the core inlet are compared. The results show the real importance of the unsteadiness characteristics of the fluid flow transport of the clear water plug. (author) 12 refs.

  10. Undulating fins produce off-axis thrust and flow structures.

    Neveln, Izaak D; Bale, Rahul; Bhalla, Amneet Pal Singh; Curet, Oscar M; Patankar, Neelesh A; MacIver, Malcolm A


    While wake structures of many forms of swimming and flying are well characterized, the wake generated by a freely swimming undulating fin has not yet been analyzed. These elongated fins allow fish to achieve enhanced agility exemplified by the forward, backward and vertical swimming capabilities of knifefish, and also have potential applications in the design of more maneuverable underwater vehicles. We present the flow structure of an undulating robotic fin model using particle image velocimetry to measure fluid velocity fields in the wake. We supplement the experimental robotic work with high-fidelity computational fluid dynamics, simulating the hydrodynamics of both a virtual fish, whose fin kinematics and fin plus body morphology are measured from a freely swimming knifefish, and a virtual rendering of our robot. Our results indicate that a series of linked vortex tubes is shed off the long edge of the fin as the undulatory wave travels lengthwise along the fin. A jet at an oblique angle to the fin is associated with the successive vortex tubes, propelling the fish forward. The vortex structure bears similarity to the linked vortex ring structure trailing the oscillating caudal fin of a carangiform swimmer, though the vortex rings are distorted because of the undulatory kinematics of the elongated fin.

  11. Turbulent pipe flow: Statistics, Re-dependence, structures and similarities with channel and boundary layer flows

    El Khoury, George K; Schlatter, Philipp; Brethouwer, Geert; Johansson, Arne V


    Direct numerical simulation data of fully developed turbulent pipe flow are extensively compared with those of turbulent channel flow and zero-pressure-gradient boundary layer flow for Re-tau up to 1 000...

  12. Crosslinked anion exchange membranes with primary diamine-based crosslinkers for vanadium redox flow battery application

    Cha, Min Suc; Jeong, Hwan Yeop; Shin, Hee Young; Hong, Soo Hyun; Kim, Tae-Ho; Oh, Seong-Geun; Lee, Jang Yong; Hong, Young Taik


    A series of polysulfone-based crosslinked anion exchange membranes (AEMs) with primary diamine-based crosslinkers has been prepared via simple a crosslinking process as low-cost and durable membranes for vanadium redox flow batteries (VRFBs). Chloromethylated polysulfone is used as a precursor polymer for crosslinked AEMs (CAPSU-x) with different degrees of crosslinking. Among the developed AEMs, CAPSU-2.5 shows outstanding dimensional stability and anion (Cl-, SO42-, and OH-) conductivity. Moreover, CAPSU-2.5 exhibits much lower vanadium ion permeability (2.72 × 10-8 cm2 min-1) than Nafion 115 (2.88 × 10-6 cm2 min-1), which results in an excellent coulombic efficiency of 100%. The chemical and operational stabilities of the membranes have been investigated via ex situ soaking tests in 0.1 M VO2+ solution and in situ operation tests for 100 cycles, respectively. The excellent chemical, physical, and electrochemical properties of the CAPSU-2.5 membrane make it suitable for use in VRFBs.

  13. Flow structure and vorticity transport on a plunging wing

    Eslam Panah, Azar

    The structure and dynamics of the flow field created by a plunging flat plate airfoil are investigated at a chord Reynolds number of 10,000 while varying plunge amplitude and Strouhal number. Digital particle image velocimetry measurements are used to characterize the shedding patterns and the interactions between the leading and trailing edge vortex structures (LEV and TEV), resulting in the development of a wake classification system based on the nature and timing of interactions between the leading- and trailing-edge vortices. The convection speed of the LEV and its resulting interaction with the TEV is primarily dependent on reduced frequency; however, at Strouhal numbers above approximately 0.4, a significant influence of Strouhal number (or plunge amplitude) is observed in which LEV convection is retarded, and the contribution of the LEV to the wake is diminished. It is shown that this effect is caused by an enhanced interaction between the LEV and the airfoil surface, due to a significant increase in the strength of the vortices in this Strouhal number range, for all plunge amplitudes investigated. Comparison with low-Reynolds-number studies of plunging airfoil aerodynamics reveals a high degree of consistency and suggests applicability of the classification system beyond the range examined in the present work. Some important differences are also observed. The three-dimensional flow field was characterized for a plunging two-dimensional flat-plate airfoil using three-dimensional reconstructions of planar PIV data. Whereas the phase-averaged description of the flow field shows the secondary vortex penetrating the leading-edge shear layer to terminate LEV formation on the airfoil, time-resolved, instantaneous PIV measurements show a continuous and growing entrainment of secondary vorticity into the shear layer and LEV. A planar control volume analysis on the airfoil indicated that the generation of secondary vorticity produced approximately one half the

  14. Effect of a distal protection device on epicardial blood flow and myocardial perfusion in primary percutaneous coronary intervention


    Objective: The beneficial effect of percutaneous coronary intervention (PCI) in patients with acute myocardial infarction (AMI) has been well established, but there is the problem of no-reflow phenomenon which is an adverse prognostic factor in primary PCI. In the present study the effect of a distal protection device (PercuSurge GuardWire; GW) on epicardial blood flow and myocardial perfusion was evaluated. Methods and Results: Patients with AMI were randomly divided into 2 groups, the GW and the control groups. The GW group included 52 patients with AMI who underwent primary PCI with GW protection and the control group included 60 patients who underwent primary PCI without GW protection. Epicardial blood flow in the infarct-related artery (IRA) and myocardial perfusion were evaluated according to the thrombolysis in myocardial infarction (TIMI) flow grade and the myocardial blush grade (MBG). We found TIMI score of 3 was obtained significantly more frequently in the GW group (96%) than in the control group (80%). The MBG score of 3 was obtained also significantly greater in the GW group (65%) than in the control group (33%). Conclusion: Primary PCI with GW protection can significantly improve epicardial blood flow and myocardial perfusion.

  15. Identification and control of large-scale structures in highly turbulent shear flow

    Schadow, K. C.; Wilson, K. J.; Gutmark, E.

    Unforced and forced subsonic jets were studied using hot-wire anemometry. It is found that highly coherent flow structure can be generated in the initial region of ducted flow by applying forcing to the flow innstability frequencies. Flow visualization experiments in water showed that the coherent structures had relatively high azimuthal coherence and were periodic in time and space. The convection velocity of the structures was about 60 percent of the mean flow velocity. Mixing of the shear layer with the surrounding recirculation zone and the inside core was enhanced by the forcing and reduced their size accordingly. Photographs from the flow visualization tests are provided.

  16. Test plan for evaluation of primary exhaust ventilation flow meters for double shell hydrogen watch list tanks

    Willingham, W.E. [Kaiser Engineers Hanford Co., Richland, WA (United States)


    This document is a plan for testing four different flow meters for use in the primary exhaust ventilation ducts of Double Shell Tanks on the hydrogen watch list that do not already have this capability. This currently includes tanks 241-AW-101, 241-AN-103, 241-AN-104, 241-AN-105, and 241-SY-103. The anticipated airflow velocity in these tanks range from 0.25 m/s(50 ft/min) to 1.78 m/s (350 ft/min). Past experiences at Hanford are forcing the evaluation and selection of instruments to be used at the low flow and relatively high humidity conditions found in these tanks. Based on the results of this test, a flow meter shall be chosen for installation in the primary exhaust ventilation ducts of the above mentioned waste tanks.

  17. Selection process for trade study: Graphite Composite Primary Structure (GCPS)

    Greenberg, H. S.


    This TA 2 document describes the selection process that will be used to identify the most suitable structural configuration for an SSTO winged vehicle capable of delivering 25,000 lbs to a 220 nm circular orbit at 51.6 degree inclination. The most suitable unpressurized graphite composite structures and material selections is within this configuration and will be the prototype design for subsequent design and analysis and the basis for the design and fabrication of payload bay, wing, and thrust structure full scale test articles representing segments of the prototype structures. The selection process for this TA 2 trade study is the same as that for the TA 1 trade study. As the trade study progresses additional insight may result in modifications to the selection criteria within this process. Such modifications will result in an update of this document as appropriate.

  18. Inflatable Habitat with Integrated Primary and Secondary Structure Project

    National Aeronautics and Space Administration — Paragon Space Development Corp (Paragon) and Thin Red Line Aerospace (TRLA) proposes to explore the utilization of inflatable structures by designing a habitation...

  19. The process flow and structure of an integrated stroke strategy

    Emma F. van Bussel


    Full Text Available Introduction: In the Canadian province of Alberta access and quality of stroke care were suboptimal, especially in remote areas. The government introduced the Alberta Provincial Stroke Strategy (APSS in 2005, an integrated strategy to improve access to stroke care, quality and efficiency which utilizes telehealth. Research question: What is the process flow and the structure of the care pathways of the APSS?Methodology: Information for this article was obtained using documentation, archival APSS records, interviews with experts, direct observation and participant observation.Results: The process flow is described. The APSS integrated evidence-based practice, multidisciplinary communication, and telestroke services. It includes regular quality evaluation and improvement.Conclusion: Access, efficiency and quality of care improved since the start of the APSS across many domains, through improvement of expertise and equipment in small hospitals, accessible consultation of stroke specialists using telestroke, enhancing preventive care, enhancing multidisciplinary collaboration, introducing uniform best practice protocols and bypass-protocols for the emergency medical services.Discussion: The APSS overcame substantial obstacles to decrease discrepancies and to deliver integrated higher quality care. Telestroke has proven itself to be safe and feasible. The APSS works efficiently, which is in line to other projects worldwide, and is, based on limited results, cost effective. Further research on cost-effectiveness is necessary.

  20. The process flow and structure of an integrated stroke strategy

    Emma F. van Bussel


    Full Text Available Introduction: In the Canadian province of Alberta access and quality of stroke care were suboptimal, especially in remote areas. The government introduced the Alberta Provincial Stroke Strategy (APSS in 2005, an integrated strategy to improve access to stroke care, quality and efficiency which utilizes telehealth. Research question: What is the process flow and the structure of the care pathways of the APSS? Methodology: Information for this article was obtained using documentation, archival APSS records, interviews with experts, direct observation and participant observation. Results: The process flow is described. The APSS integrated evidence-based practice, multidisciplinary communication, and telestroke services. It includes regular quality evaluation and improvement. Conclusion: Access, efficiency and quality of care improved since the start of the APSS across many domains, through improvement of expertise and equipment in small hospitals, accessible consultation of stroke specialists using telestroke, enhancing preventive care, enhancing multidisciplinary collaboration, introducing uniform best practice protocols and bypass-protocols for the emergency medical services. Discussion: The APSS overcame substantial obstacles to decrease discrepancies and to deliver integrated higher quality care. Telestroke has proven itself to be safe and feasible. The APSS works efficiently, which is in line to other projects worldwide, and is, based on limited results, cost effective. Further research on cost-effectiveness is necessary.

  1. Symmetry Broken Exact Coherent Structures in Plane Couette Flow

    Gopalaswamy, Varchas; Borrero-Echeverry, Daniel


    Invariant solutions of the fully resolved Navier-Stokes equation, known as exact coherent structures (ECS) are an exciting and potentially revolutionary method for understanding turbulent dynamics. The geometry of plane Couette flow leads to the existence of ECS with a high degree of symmetry. However, turbulent flows do not display a high degree of symmetry, so it is unclear whether these symmetric ECS can truly capture the turbulent dynamics. We report the discovery of four new periodic orbits - P85 and P60 which are fully symmetric, and P32 and P8, which have partially broken symmetry. Projections of these periodic orbits in the dissipation-energy input plane reveal that P32, P60 and P85 lie in the turbulent region of the state space, whereas P8 lies very far away from this region. Parametric continuation in the spanwise periodic cell length Lz suggests that P8 undergoes two bifurcations, which are verified by analysis of various properties of P8 in the dissipation-energy input plane, and by observations of changes in the stability of eigenvectors that are consistent with bifurcations.

  2. Turbulence Modification Structures in an Upward Bubbly Pipe Flow

    Tanaka, Tomohiko; Hishida, Koichi; Eaton, John


    The objective of this study is to investigate the mechanism of modification of turbulence in gas-liquid bubbly flow. We especially focused on the effect of void fraction and bubble diameter, which are important factors in turbulence modification. Fluid velocity was measured by applying PIV with fluorescent tracer particles, and bubble shapes and positions were obtained by the shadow-image technique. The experiment consisted of a fully developed vertical upward pipe flow with void fraction 0.5diameter is 2R=44mm and the Re=9700. In order to compare the effect of the bubble diameter at fixed void fraction, nearly 60ppm of 3-Pentanol (C5H11OH) surfactant was added as the surfactant. Bubbles accelerated the mean streamwise velocity near the wall. Thus the mean streamwise velocity profile was flatted. Moreover, the streamwise fluctuation velocity was suppressed at the middle pipe region. It is suggested that the highly concentrated bubbles in the vicinity of the wall disturb the transport of turbulence energy produced by the wall shear layer toward the middle of pipe. Thus the fluctuation velocity is remarkably reduced at the wide region of the pipe center. Moreover, in the middle of pipe, the turbulence structure is governed by the presence of bubbles.

  3. A survey of air flow models for multizone structures

    Feustel, H.E.; Dieris, J.


    Air flow models are used to simulate the rates of incoming and outgoing air flows for a building with known leakage under given weather and shielding conditions. Additional information about the flow paths and air-mass flows inside the building can only by using multizone air flow models. In order to obtain more information on multizone air flow models, a literature review was performed in 1984. A second literature review and a questionnaire survey performed in 1989, revealed the existence of 50 multizone air flow models, all developed since 1966, two of which are still under development. All these programs use similar flow equations for crack flow but differ in the versatility to describe the full range of flow phenomena and the algorithm provided for solving the set of nonlinear equations. This literature review was found that newer models are able to describe and simulate the ventilation systems and interrelation of mechanical and natural ventilation. 27 refs., 2 figs., 1 tab.

  4. Flow Structure Around the Intake of a Vertical Pump

    Akihiro WADA


    The flow structure around the intake of a vertical pump is investigated experimentally and numerically in order to obtain a guideline in designing the optimum shape of the intake of vertical pumps, in which their installation area is demanded to be minimum without losing the high performance. We concentrate our attention on the expansion ratio of the intake as a representative characteristic of the shape of the pumps and investigate the effect of the expansion ratio on pump performance. It is concluded that the optimum expansion ratio ranges in 1.1~1.2 if we take into consideration that the area needed for the installation of the pump should be minimum.

  5. Flow structures in the wake of heaving and pitching foils

    Najdzin, Derek; Pardo, Enrique; Leftwich, Megan C.; Bardet, Philippe M.


    A 10-bar mechanism drives a cambering hydrofoil in an oscillatory heaving and pitching motion that replicates the flapping motion of a dolphin tail. The mechanism sits on a force-balance with six strain gages that together measure the forces and moments experienced by the fin during an oscillation. Planar Laser-Induced Fluorescence is used to image the flow structures created downstream of the cambering fin for a range of Reynolds and Strouhal numbers. The images are taken in the mid-plane, parallel to the bottom of the water tunnel. These results are compared to a rigid foil at matching conditions to investigate the role of camber changes during the flapping cycle.

  6. Shock front width and structure in supersonic granular flows.

    Boudet, J F; Amarouchene, Y; Kellay, H


    The full structure of a shock front around a blunt body in a quasi-two-dimensional granular flow is studied. Two features, a large density gradient and a very small thickness of the front, characterize this shock and make it different from shocks in molecular gases. Both of these features can be understood using a modified version of the granular kinetic theory. Our model separates the particles into two subpopulations: fast particles having experienced no collisions and randomly moving particles. This separation is motivated by direct measurements of the particle velocities which show a bimodal distribution. Our results not only shed new light on the use of the granular kinetic theory under extreme conditions (shock formation) but bring new insight into the physics of shocks in general.

  7. Primary structure of human alpha 2-macroglobulin. V. The complete structure

    Sottrup-Jensen, Lars; Stepanik, Terrence M; Kristensen, Torsten


    The primary structure of the tetrameric plasma glycoprotein human alpha 2-macroglobulin has been determined. The identical subunits contain 1451 amino acid residues. Glucosamine-based oligosaccharide groups are attached to asparagine residues 32, 47, 224, 373, 387, 846, 968, and 1401. Eleven...... in the activation cleavage area (the "bait" region) are located in the sequence: -Arg681-Val-Gly-Phe-Tyr-Glu-. The molecular weight of the unmodified alpha 2-macroglobulin subunit is 160,837 and approximately 179,000, including the carbohydrate groups. The presence of possible internal homologies within the alpha 2......-macroglobulin subunit is discussed. A comparison of stretches of sequences from alpha 2-macroglobulin with partial sequence data for complement components C3 and C4 indicates that these proteins are evolutionary related. The properties of alpha 2-macroglobulin are discussed within the context of proteolytically...

  8. Coherent structures and flow topology of transitional separated-reattached flow over two and three dimensional geometrical shapes

    Diabil, Hayder Azeez; Li, Xin Kai; Abdalla, Ibrahim Elrayah


    Large-scale organized motions (commonly referred to coherent structures) and flow topology of a transitional separated-reattached flow have been visualised and investigated using flow visualisation techniques. Two geometrical shapes including two-dimensional flat plate with rectangular leading edge and three-dimensional square cylinder are chosen to shed a light on the flow topology and present coherent structures of the flow over these shapes. For both geometries and in the early stage of the transition, two-dimensional Kelvin-Helmholtz rolls are formed downstream of the leading edge. They are observed to be twisting around the square cylinder while they stay flat in the case of the two-dimensional flat plate. For both geometrical shapes, the two-dimensional Kelvin-Helmholtz rolls move downstream of the leading edge and they are subjected to distortion to form three-dimensional hairpin structures. The flow topology in the flat plate is different from that in the square cylinder. For the flat plate, there is a merging process by a pairing of the Kelvin-Helmholtz rolls to form a large structure that breaks down directly into many hairpin structures. For the squire cylinder case, the Kelvin-Helmholtz roll evolves topologically to form a hairpin structure. In the squire cylinder case, the reattachment length is much shorter and a forming of the three-dimensional structures is closer to the leading edge than that in the flat plate case.




    An adaptive finite element method for high-speed flow-structure interaction is presented. The cell-centered finite element method is combined with an adaptive meshing technique to solve the Navier-Stokes equations for high-speed compressible flow behavior. The energy equation and the quasi-static structural equations for aerodynamically heated structures are solved by applying the Galerkin finite element method. The finite element formulation and computational procedure are described. Interactions between the high-speed flow, structural heat transfer, and deformation are studied by two applications of Mach 10 flow over an inclined plate, and Mach 4 flow in a channel.


    陈洪凯; 唐红梅; 吴四飞


    As one weak topic in research of debris flow, abrasion of debris flow shortens obviously application life of control structure composed of concrete. High-speed drainage structure, one of the most effective techniques to control giant debris flow disaster, has shortened one-third application life due to abrasion by debris flow. Based on velocity calculation method founded by two-phase theory, research of abrasion mechanism of debris flow to high-speed drainage structure was made. The mechanism includes both abrasion mechanism of homogeneous sizing and shearing mechanism of particle of debris flow to high-speed drainage trough structure. Further abrasion equations of both sizing and particle were established by Newton movement theory of debris flow. And abrasion amount formula of the high-speed drainage trough structure is set up by dimensional analysis. Amount to calculating in the formula is consistent with testing data in-situ, which is valuable in design of high-speed drainage structure.

  11. Trade study plan for Graphite Composite Primary Structure (GCPS)

    Greenberg, H. S.


    This TA 2 document (with support from TA 1) describes the trade study plan that will identify the most suitable structural configuration for an SSTO winged vehicle capable of delivering 25,000 lbs to a 220 nm circular orbit at 51.6 degree inclination For this most suitable configuration the structural attachment of the wing, and the most suitable GCPS composite materials for intertank, wing, tail and thrust structure are identified. This trade study analysis uses extensive information derived in the TA 1 trade study plan and is identified within the study plan. In view of this, for convenience, the TA 1 study plan is included as an appendix to this document.

  12. Potential structural barriers to ground-water flow, Death Valley regional ground-water flow system, Nevada and California

    U.S. Geological Survey, Department of the Interior — This digital dataset defines the surface traces of regional geologic structures designated as potential ground-water flow barriers in an approximately 45,000...

  13. Potential structural barriers to ground-water flow, Death Valley regional ground-water flow system, Nevada and California

    U.S. Geological Survey, Department of the Interior — This digital dataset defines the surface traces of regional geologic structures designated as potential ground-water flow barriers in an approximately 45,000...

  14. Asymetrical structure in coastal river flows and jets

    Redondo, Jose M.; Sekula, Emil; Bateman, Allen


    We apply visual scaling methods to both laboratory experiments and to satellite images of coastal flows as a tool to understand jet/boundary interactions in the environment. We compare the structure of SAR(Synthetic Aperture Radar) images of coastal jets and vortices and to experiments of jets of different Reynolds numbers and their images searching for common scaling and structural relationship between these two kinds of jets taking advantage of the self-similarity of the mixing processes. In order to investigate the structure of ocean surface detected jets (SAR)and vortices near the coast, we compare wall and boundary effects on the structure of turbulent jets (3D and 2D) which are non-homogeneous. We also use the multifractal analysis of SAR and experimental jets (plumes) images looking for relationship between these two kinds of jets. The SAR images exhibit a large variation of natural features produced by winds, internal waves, the bathymetric distribution, by thermal or solutal convection by rain, etc. These produce variations in the sea surface roughness. The satellite-borne SAR is able to detect oceanic features with a range of scales. The spatial cross-correlation may give an indication of the length over which such features are correlated. We compare the inner and outer jet boundaries detecting a clear asymetry, A similar effect is detected in laboratory experiments at large Reynolds number when a wall is near one of the sides of the jet. The geometrical constrains are seen to affect also the scale to scale energy transfer.

  15. A new debris flow monitoring barrier to measure debris flow impact/structure/ground interaction in the Gadria torrent

    Nagl, Georg; Hübl, Johannes


    Debris flow monitoring is a keystone in debris flow research. Based on the lack of investigations of the interaction of rapid mass movement and structural mitigation measures, a new monitoring system has been installed in the well monitored Gadria torrent in South Tyrol. For design of active structural measures, like check dams, the engineering task is to come to an amicable solution of all necessary subjects. Starting with the estimation of parameters of the rapid mass movement itself to the design load and finally to the foundation of the structure. At all stages big uncertainties are given. The basis for accurate design is a comprehensive approach. For this reason, a new monitoring station was built in autumn 2016, to investigate the interaction of a debris flow with the structures and the ground. Two structures unify the new monitoring system. The first, a transversal check dam, flush to channel bed, contain two weighing devices each equipped with a pore pressure sensor. One device is also able to measure the shear force additional in two directions. The second barrier similar to a debris flow breaker but only with one singe wall centered on a foundation plate, is located downstream to the first one. 14 load cells are installed on the upward front of the structure to analyze the spatial force distribution of debris flow impact pressure. Nine earth pressure sensors under the foundation of the structure deliver the earth pressure distribution. The acceleration of the construction can be measured by a 3D accelerometer installed on the top. In case of a movement, two extensometers detect any displacement. Mounted strain gauges give insights of stresses in concrete and reinforcement. Each sensor has a sampling frequency of 2400 Hz. Furthermore it is planned to measure the flow velocity distribution over flow depth too. The new monitoring station should help to acquire data for understanding the debris flow/structure/ground interaction to facilitate the improvement

  16. Final Report: Comparison of the primary (national) standards of low-pressure gas flow

    Benková, Miroslava; Makovnik, Stefan; Mickan, Bodo


    The EURAMET.M.FF-K6 comparison was organized for the purpose of determination of the degree of equivalence of the primary (national) standards for low-pressure gas flow measurement over the range (2 to 100) m3/h and was performed simultaneously with CCM.FF-K6.2011 with the same transfer standard. A rotary gas meter G65 was used as a transfer standard. The measurements were provided by prescribed reference conditions. Fifteen laboratories from EURAMET participated in this key comparison - SMU, Slovakia; PTB, Germany; CEM, Spain; LNE-LADG, France; VSL, Netherlands; CMI, Czech Republic; BEV, Austria; MKEH, Hungary; GUM Poland; SP, Sweden; METAS, Switzerland; DMDM, Serbia; TUBITAK-UME, Turkey; EIM, Greece; IMBiH, Bosnia-Herzegovina. The EURAMET.M.FF-K6 is linked to the CCM.FF-K6.2011 by correcting the results of three linking laboratories (Slovakia SMU, Germany PTB and France LNE LADG). This correction provides an estimate of what would have been the result from the EURAMET.M-FF-K6 participants, if they had actually participated in CCM.FF-K6.2011. According to the evaluation 93.7 % of the results were consistent with KCRV, 3.4 % of the results were in the warning level and 2.9 % of the results were inconsistent. The results of this comparison can be used for review of the CMC tables. Main text. To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database The final report has been peer-reviewed and approved for publication by CCM, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).

  17. Cosmic Flows and the Structure of the Local Universe

    Steinmetz, Matthias


    The Local Volume is the area of the cosmos we can analyze in most detail with respect to the properties of its galaxy population, their abundance, their inner structure, their distribution, and their formation. Indeed, many challenges of the cosmological concordance model such as the substructure crisis or the surprising occurrence of vast planes of satellite galaxies are intimately linked to observations of the local galaxy population. However, owing to the peculiar environment of our Milky Way system and its cosmic neighborhood, the Local Volume may also be severely biased. Cosmography, i.e. the reconstruction of the local cosmic web from cosmic flows, and constrained simulations of structure formation as a tool to produce simulated local group analogues provide a powerful method to analyze and quantify these biases. Possible applications include the analysis of the local distribution of dwarf galaxies around luminous galaxies and the characterization of the mass accretion history of these objects. Thanks to the extension of galaxy velocity data out to distances in excess of 200Mpc, we are now capable to reconstruct the 3D matter distribution out to these distances, thus constraining the formation history of object such as the Virgo Cluster.

  18. Dynamics of driven flow with exclusion in graphenelike structures

    Stinchcombe, R. B.; de Queiroz, S. L. A.


    We present a mean-field theory for the dynamics of driven flow with exclusion in graphenelike structures, and numerically check its predictions. We treat first a specific combination of bond transmissivity rates, where mean field predicts, and numerics to a large extent confirms, that the sublattice structure characteristic of honeycomb networks becomes irrelevant. Dynamics, in the various regions of the phase diagram set by open boundary injection and ejection rates, is then in general identical to that of one-dimensional systems, although some discrepancies remain between mean-field theory and numerical results, in similar ways for both geometries. However, at the critical point for which the characteristic exponent is z =3 /2 in one dimension, the mean-field value z =2 is approached for very large systems with constant (finite) aspect ratio. We also treat a second combination of bond (and boundary) rates where, more typically, sublattice distinction persists. For the two rate combinations, in continuum or late-time limits, respectively, the coupled sets of mean-field dynamical equations become tractable with various techniques and give a two-band spectrum, gapless in the critical phase. While for the second rate combination quantitative discrepancies between mean-field theory and simulations increase for most properties and boundary rates investigated, theory still is qualitatively correct in general, and gives a fairly good quantitative account of features such as the late-time evolution of density profile differences from their steady-state values.

  19. Correlations of Flow Structure and Particle Deposition with Structural Alterations in Severe Asthmatic Lungs

    Choi, Sanghun; Miyawaki, Shinjiro; Choi, Jiwoong; Hoffman, Eric A.; Wenzel, Sally; Lin, Ching-Long


    Severe asthmatics are characterized by alterations of bifurcation angle, hydraulic diameter, circularity of the airways, and local shift of air-volume functional change. The characteristics altered against healthy human subjects can affect flow structure and particle deposition. A large-eddy-simulation (LES) model for transitional and turbulent flows is utilized to study flow characteristics and particle deposition with representative healthy and severe asthmatic lungs. For the subject-specific boundary condition, local air-volume changes are derived with two computed tomography images at inspiration and expiration. Particle transport simulations are performed on LES-predicted flow fields. In severe asthmatics, the elevated air-volume changes of apical lung regions affect the increased particle distribution toward upper lobes, especially for small particles. The constricted airways are significantly correlated with high wall shear stress, leading to the increased pressure drop and particle deposition. The structural alterations of bifurcation angle, circularity and hydraulic diameter in severe asthmatics are associated with the increase of particle deposition, wall shear stress and wall thickness. NIH Grants: U01-HL114494, R01-HL094315 and S10-RR022421. Computer time: XSEDE.

  20. Relationship between Professional Learning Community, Bureaucratic Structure and Organisational Trust in Primary Education Schools

    Kalkan, Fatma


    This research uses relational survey method to determine the relationship between professional learning community, bureaucratic structure and organisational trust according to the perceptions of teachers who work in primary education schools. Data were collected from 805 teachers who work in primary education schools in the districts (Altindag,…

  1. The effects of flow on schooling Devario aequipinnatus: school structure, startle response and information transmission

    Chicoli, A.; Butail, S.; Lun, Y.; Bak-Coleman, J.; Coombs, S; Paley, D.A.


    To assess how flow affects school structure and threat detection, startle response rates of solitary and small groups of giant danio Devario aequipinnatus were compared to visual looming stimuli in flow and no-flow conditions. The instantaneous position and heading of each D. aequipinnatus were extracted from high-speed videos. Behavioural results indicate that (1) school structure is altered in flow such that D. aequipinnatus orient upstream while spanning out in a crosswise direction, (2) t...


    Pasxou D.


    Full Text Available BACKGROUND: The relative absence of inquiring data internationally, with regard to the relation of woman, family and work as important sources of stress, in the professional team of district nurses, gave the spark for the planning of present study. AIM: We have conducted a study to identify levels of stress, job satisfaction, and effects of the job to the family life and reversely, among district nurses (nurses and nurse assistantsworking in primary health care settings in central Greece (Thessaly. METHODS: Data were obtained regarding altogether 92 nurses by means of self-administered questionnaires using identical methods and items, with response rate 100%. RESULTS: District nurses believe in the necessity of high educational sufficiency for the achievement of professional evolution, present high levels of satisfaction from the object and their place of work. They reported high levels of stress that exceed the corresponding levels in the Greek population. Nurses appear to be more satisfied from work than nurse assistants. The implications of the findings for further research are considered.

  3. A structured model of video reproduces primary visual cortical organisation.

    Pietro Berkes


    Full Text Available The visual system must learn to infer the presence of objects and features in the world from the images it encounters, and as such it must, either implicitly or explicitly, model the way these elements interact to create the image. Do the response properties of cells in the mammalian visual system reflect this constraint? To address this question, we constructed a probabilistic model in which the identity and attributes of simple visual elements were represented explicitly and learnt the parameters of this model from unparsed, natural video sequences. After learning, the behaviour and grouping of variables in the probabilistic model corresponded closely to functional and anatomical properties of simple and complex cells in the primary visual cortex (V1. In particular, feature identity variables were activated in a way that resembled the activity of complex cells, while feature attribute variables responded much like simple cells. Furthermore, the grouping of the attributes within the model closely parallelled the reported anatomical grouping of simple cells in cat V1. Thus, this generative model makes explicit an interpretation of complex and simple cells as elements in the segmentation of a visual scene into basic independent features, along with a parametrisation of their moment-by-moment appearances. We speculate that such a segmentation may form the initial stage of a hierarchical system that progressively separates the identity and appearance of more articulated visual elements, culminating in view-invariant object recognition.

  4. Modelling of structural effects on chemical reactions in turbulent flows

    Gammelsaeter, H.R.


    Turbulence-chemistry interactions are analysed using algebraic moment closure for the chemical reaction term. The coupling between turbulence and chemical length and time scales generate a complex interaction process. This interaction process is called structural effects in this work. The structural effects are shown to take place on all scales between the largest scale of turbulence and the scales of the molecular motions. The set of equations describing turbulent correlations involved in turbulent reacting flows are derived. Interactions are shown schematically using interaction charts. Algebraic equations for the turbulent correlations in the reaction rate are given using the interaction charts to include the most significant couplings. In the frame of fundamental combustion physics, the structural effects appearing on the small scales of turbulence are proposed modelled using a discrete spectrum of turbulent scales. The well-known problem of averaging the Arrhenius law, the specific reaction rate, is proposed solved using a presumed single variable probability density function and a sub scale model for the reaction volume. Although some uncertainties are expected, the principles are addressed. Fast chemistry modelling is shown to be consistent in the frame of algebraic moment closure when the turbulence-chemistry interaction is accounted for in the turbulent diffusion. The modelling proposed in this thesis is compared with experimental data for an laboratory methane flame and advanced probability density function modelling. The results show promising features. Finally it is shown a comparison with full scale measurements for an industrial burner. All features of the burner are captured with the model. 41 refs., 33 figs.

  5. Flow in Porous Media with Special Reference to Breakwater Structures

    Andersen, O. Holst

    A literature study concerning porous flow is carried out. For the stationary case, the hydraulic radius theory, for which some justification can be given based on Navier-Stokes equations, appears to be adequate. Three different porous flow regimes are identified and the associated flow resistance...... of large scale physical experiments carried out in collaboration with other researchers....

  6. Mechanical Attachment of Reusable Surface Insulation to Space Shuttle Primary Structure

    Fleck, R. W.; Lehman, J. K.


    Three methods of attaching surface insulation tiles to shuttle primary structure have been proposed: direct bond, mechanical attachment, and subpanels with standoffs. The direct bond approach is lightweight but is difficult to refurbish and inspect. The subpanel approach is heavier but allows for easy refurbishment since subpanels are easily removed and replaced. The mechanical attachment approach allows easy refurbishment and inspection and is lightweight when an efficient insulator is used between surface insulation tiles and primary structure.

  7. The flow field structure of highly stabilized partially premixed flames in a concentric flow conical nozzle burner with coflow

    Elbaz, Ayman M.


    The stability limits, the stabilization mechanism, and the flow field structure of highly stabilized partially premixed methane flames in a concentric flow conical nozzle burner with air co-flow have been investigated and presented in this work. The stability map of partial premixed flames illustrates that the flames are stable between two extinction limits. A low extinction limit when partial premixed flames approach non-premixed flame conditions, and a high extinction limit, with the partial premixed flames approach fully premixed flame conditions. These two limits showed that the most stable flame conditions are achieved at a certain degree of partial premixed. The stability is improved by adding air co-flow. As the air co-flow velocity increases the most stable flames are those that approach fully premixed. The turbulent flow field of three flames at 0, 5, 10 m/s co-flow velocity are investigated using Stereo Particle Image Velocimetry (SPIV) in order to explore the improvement of the flame stability due to the use of air co-flow. The three flames are all at a jet equivalence ratio (Φj) of 2, fixed level of partial premixing and jet Reynolds number (Rej) of 10,000. The use of co-flow results in the formation of two vortices at the cone exit. These vortices act like stabilization anchors for the flames to the nozzle tip. With these vortices in the flow field, the reaction zone shifts toward the reduced turbulence intensity at the nozzle rim of the cone. Interesting information about the structure of the flow field with and without co-flow are identified and reported in this work.

  8. Modelling the structural controls of primary kaolinite formation

    Tierney, R. L.; Glass, H. J.


    An abundance of kaolinite was formed within the St. Austell outcrop of the Cornubian batholith in Cornwall, southwest England, by the hydrous dissolution of feldspar crystals. The permeability of Cornish granites is low and alteration acts pervasively from discontinuity features, with montmorillonite recognised as an intermediate assemblage in partially kaolinised material. Structural features allowed fluids to channel through the impermeable granite and pervade deep into the rock. Areas of high structural control are hypothesised to link well with areas of advanced alteration. As kaolinisation results in a loss of competence, we present a method of utilising discontinuity orientations from nearby unaltered granites alongside the local tectonic history to calculate strain rates and delineate a discrete fracture network. Simulation of the discrete fracture network is demonstrated through a case study at Higher Moor, where kaolinite is actively extracted from a pit. Reconciliation of fracture connectivity and permeability against measured subsurface data show that higher values of modelled properties match with advanced kaolinisation observed in the field. This suggests that the technique may be applicable across various industries and disciplines.

  9. Examining the impact of ambient flow on biofilm and its feedback on the flow structure through a fluid-structure interaction (FSI) solver

    Hardy, R. J.; Sinha, S.; Sambrook Smith, G.; Kazemifar, F.; Christensen, K.; Best, J.


    Biofilms are ubiquitously present in fluvial systems, growing on almost all wetted surface. The local hydraulic conditions have a significant impact on the biofilm lifecycle as in order to sustain their growth biofilms draw essential nutrients either from the flow or from the surface on which they grow. This implies that in convection dominated flow, nutrient transfer from water, would nurture the growth of biofilms. However, at higher flow rates biofilms are subjected to higher stresses which may lead to their detachment. Furthermore, biofilms in ambient flow conditions oscillate and therefore alter the local flow conditions. There is, therefore, a complex feedback between biofilms and flow which have has implications for flow dynamics and water quality issues in riverine ecosystems. The research presented here describes a fluid-structure interaction solver to examine the coupled nature of biofilm oscillations due to the ambient flow and its feedback on the local flow structures. The fluid flow is modelled by the incompressible Navier-Stokes equations and structural deformation of the biofilm is modeled by applying a linear elastic model. The governing equations are numerically solved through Finite Volume methodology based on cell-centered scheme. Simulations are conducted in a laminar regime for a biofilm streamer modelled as moving slender plate. The temporal evolution of the pressure, flow structures are examined in the vicinity of the biofilm. Further investigations examine the impact of changing Reynolds number on the oscillation frequency as well as drag and lift forces experienced by the biofilm. The changing frequency of biofilm oscillation with varying Reynolds number is characterized by the Strouhal number (St). Our investigation reveals that as the flow separates around the biofilm attachment point, vortices are formed both above and beneath the biofilm which propagate downstream. As the vortex rolls off from the end of the biofilm, the interaction

  10. Dislocation structures and anomalous flow in L12 compounds

    Dimiduk, D. M.


    The theory of the anomalous flow behavior of LI2 compounds has developed over the last 30 years. This theory has a foundation in the early estimates of the crystallographic anisotropy of antiphase boundary (APB) energy in these compounds. In spite of this critical aspect of the theory, it is only in the last five years that electron microscopy has been employed to quantify the APB energies and to determine the detailed nature of dislocation structures at each stage of deformation. The recent studies of several research groups have provided essentially consistent new details about the nature of dislocations in Ni3AI and a few other LI2 compounds which exhibit anomalous flow behavior. These studies have introduced several new concepts for the controlling dislocation mechanisms. Additionally, these studies have shown that in Ni3AI, the APB energies have only small variations in magnitude with change of the APB plane (they are nearly isotropic), are relatively insensitive to changes in solute content, and the anisotropy ratio does not correlate with alloy strength. The present manuscript provides a critical review of the new transmission electron microscopy (TEM) results along with the new concepts for the mechanism of anomalous flow. Inconsistencies and deficiencies within these new concepts are identified and discussed. The collective set of electron-microscopy results is discussed within the context of both the mechanical behavior of LI2 compounds and the Greenberg and Paidar, Pope and Vitek (PPV) models for anomalous flow. Conceptual consistency with these models can only be constructed if the Kear-Wilsdorf (K-W) configurations are treated as an irreversible work hardening or relaxation artifact and, specific details of these two models cannot be shown by electron microscopy. Alternatively, the structural features recently revealed by electron microscopy have not been assembled into a self-consistent model for yielding which fully addresses the mechanical behavior

  11. Automatic system for air flow control in air-tight chambers of the NPP primary circuit

    Bersenev, V.L.; Bagautdinov, Z.S.; Panov, S.Yu.


    A system for automatic control of air flows is briefly described which is based on a tensometric flow rate sensor. A sensitive element of the sensor, made of paper-based laminate, under the effect of incoming air flow travels, causing a bending of an elastic element, made of stainless steel. The deformation causes changes in the electric resistance of tensoresistors, the degree of a change being proportional to the air flow rate. A 400 Ohm tensoresistor is used in the sensor. Errors in the flow rate measurement using the tensometric sensor does not exceed +-3% even in the low rate air flow range. The system, tested at the Beloyarsk NPP, has shown a high reliability and accuracy of measurements, which permits to recommend it for the use in technological ventilation of NPPs.

  12. Primary standards for measuring flow rates from 100 nl/min to 1 ml/min - gravimetric principle.

    Bissig, Hugo; Petter, Harm Tido; Lucas, Peter; Batista, Elsa; Filipe, Eduarda; Almeida, Nelson; Ribeiro, Luis Filipe; Gala, João; Martins, Rui; Savanier, Benoit; Ogheard, Florestan; Niemann, Anders Koustrup; Lötters, Joost; Sparreboom, Wouter


    Microflow and nanoflow rate calibrations are important in several applications such as liquid chromatography, (scaled-down) process technology, and special health-care applications. However, traceability in the microflow and nanoflow range does not go below 16 μl/min in Europe. Furthermore, the European metrology organization EURAMET did not yet validate this traceability by means of an intercomparison between different National Metrology Institutes (NMIs). The NMIs METAS, Centre Technique des Industries Aérauliques et Thermiques, IPQ, Danish Technological Institute, and VSL have therefore developed and validated primary standards to cover the flow rate range from 0.1 μl/min to at least 1 ml/min. In this article, we describe the different designs and methods of the primary standards of the gravimetric principle and the results obtained at the intercomparison for the upper flow rate range for the various NMIs and Bronkhorst High-Tech, the manufacturer of the transfer standards used.

  13. Brittle, flowing structures focused on subtle crustal heterogeneities

    Soden, A. M.; Shipton, Z. K.; Lunn, R. J.; Pytharouli, S.; Kirkpatrick, J. D.


    Fundamental to the development of groundwater flow models are geological models that accurately account for the spatial distribution and geometrical attributes of fracture systems in three dimensions, at both seismic and sub-seismic resolution. Accurate characterization of fracture populations in crystalline rock is of particular importance, as these are the principal targets for nuclear waste repositories and enhanced geothermal systems. Fracture models are populated using average properties from site specific outcrop and borehole data, geophysical imaging and empirical scaling relationships such as the decrease of fracture density with distance from a fault surface However, host rock heterogeneity is likely to be of equal importance in influencing fracture attributes. Our study focuses on brittle structures associated with a regional NE-SW ductile shear zone in NE Brazil. Detailed field mapping shows two phases of brittle structure overprinting a ductile shear zone: 1) a brittle fault zone, which is largely "sealed" to flow, 2) a later set of open fractures. The earliest brittle fault is 1.4 - 2.6m wide zone of chaotic breccia bound by two sub-vertical fault walls. Extremely indurated breccias branching from the fault core have an orientation consistent with sinistral motion on the fault. The breccia is composed of centimeter to meter scale clasts in a fine-grained matrix. The host rock is intensely fractured by centimeter-scale fractures up to 60 m away from the fault. Veining is predominantly concentrated within 15 meters of the fault wall, and joints beyond this are unmineralised. The latest brittle deformation is represented by meter-scale open discrete fractures and fracture zones, up to 80 meters from the main fault. The fractures are unmineralised suggesting formation at relatively shallow depths. Fracture zones vary from decimeters long en echelon fractures to intensely fractured zones where the host rock is completely fragmented. This final phase of

  14. Structure development during chaotic mixing in the journal bearing flow

    Galaktionov, O. S.; Anderson, P. D.; Peters, G. W. M.


    Laminar mixing in the two-dimensional time-periodic Stokes flows between eccentric cylinders [journal bearing flow (JBF)] is studied using the extended mapping method [Galaktionov [et al.], Int. J. Multiphase Flows 28, 497 (2002)] with the emphasis on the material stretching, e.g., the interface generation abilities, of the flow. With this flexible and computational advantageous method both, the macroscopic material transport and the evolution of the microstructure can be described. It enables a convenient way for studying the material stretching in the flow and moreover, it provides spatial distribution of locally averaged stretching values instead of pointwise statistics, which was typical for previous studies [Liu [et al.], AIChE J. 40, 1273 (1994); Muzzio [et al.], Phys. Fluids A 3, 822 (1991)]. The results clearly indicate how the total amount of stretching generated by the flow depends on the parameters of the flow protocol, and that this is not just proportional to the work done on the system, as was suggested earlier in Muzzio [et al.], Phys. Fluids A 3, 822 (1991). It was found that when self-similar patterns are established, distinctive zones in the flow, which we call "microstructural demixing zones," are observed, where interfaces are contracted during a typical period of the mixing process. Spatial nonuniformity of stretching in chaotic flows calls for additional mixing measures that reflect the nonuniformity of self-similar stretching patterns, created by time-periodic mixing flows.

  15. Structure and flow calculation of cake layer on microfiltration membranes

    Yadong Yu; Zhen Yang; Yuanyuan Duan


    Submerged membrane bioreactors (SMBR) are widely used in wastewater treatment.The permeability of a membrane declines rapidly because of the formation of a cake layer on the membrane surface.In this paper,a multiple staining protocol was conducted to probe the four major foulants in the cake layer formed on a filtration membrane.Fluorescent images of the foulants were obtained using a confocal laser scanning microscope (CLSM).The three dimensional structure of the cake layer was reconstructed,and the internal flow was calculated using computational fluid dynamics (CFD).Simulation results agreed well with the experimental data on the permeability of the cake layer during filtration and showed better accuracy than the calculation by Kozeny-Carman method.β-D-Glucopyranose polysaccharides and proteins are the two main foulants with relatively large volume fractions,while α-D-glucopyranose polysaccharides and nucleic acids have relatively large specific surface areas.The fast growth of β-D-glucopyranose polysaccharides in the volume fraction is mainly responsible for the increase in cake volume fraction and the decrease in permeability.The specific area,or the aggregation/dispersion of foulants,is less important to its permeability compared to its volume fraction.

  16. Flow structure in turbulent rotating Rayleigh-Bénard convection

    Kunnen, Rudie; Corre, Yoann; Clercx, Herman


    Turbulent Rayleigh-Bénard convection is usually studied in an upright cylinder. The addition of axial rotation has profound effects on the flow structuring. The well-known large-scale circulation (LSC) of the non-rotating case is still found at low rotation rates but is replaced by an irregular array of vertically aligned vortical plumes at higher rotation rates. We report PIV measurements of turbulent rotating convection in a cylindrical cell of diameter-to-height aspect ratio Γ = 1 / 2 at Rayleigh number Ra = 4 . 5 ×109 and at many rotation rates covering both the LSC and the vortical-plume regime. We focus on: (i) the azimuthal precession of the LSC, (ii) collective motions of the vortical plumes, and (iii) the sidewall boundary layers. With these results we can clarify remarkable differences between the Γ = 1 and Γ = 1 / 2 cases reported recently in the literature. Traineeship project carried out in Eindhoven as part of Master's Degree at Université Paris-Sud, France.

  17. Convex and Network Flow Optimization for Structured Sparsity

    Mairal, Julien; Obozinski, Guillaume; Bach, Francis


    We consider a class of learning problems regularized by a structured sparsity-inducing norm defined as the sum of l_2 or l_infinity norms over groups of variables. Whereas much effort has been put in developing fast optimization techniques when the groups are disjoint or embedded in a hierarchy, we address here the case of general overlapping groups. To this end, we present two different strategies: On the one hand, we show that the proximal operator associated with a sum of l_infinity norms can be computed exactly in polynomial time by solving a quadratic minimum cost flow problem, allowing the use of accelerated proximal gradient methods. On the other hand, we use proximal splitting techniques, and address an equivalent formulation with non-overlapping groups, but in higher dimension and with additional constraints. We propose efficient and scalable algorithms exploiting these two strategies, which are significantly faster than alternative approaches. We illustrate these methods with several problems such a...

  18. Continuous-flow synthesis of primary amines: Metal-free reduction of aliphatic and aromatic nitro derivatives with trichlorosilane

    Riccardo Porta


    Full Text Available The metal-free reduction of nitro compounds to amines mediated by trichlorosilane was successfully performed for the first time under continuous-flow conditions. Aromatic as well as aliphatic nitro derivatives were converted to the corresponding primary amines in high yields and very short reaction times with no need for purification. The methodology was also extended to the synthesis of two synthetically relevant intermediates (precursors of baclofen and boscalid.

  19. Avocado sunblotch viroid: primary sequence and proposed secondary structure.

    Symons, R H


    The sequence of the 247 nucleotide residues of the single strand circular RNA of avocado sunblotch viroid (ASBV) was determined using partial enzymic cleavage methods on overlapping viroid fragments obtained by partial ribonuclease digestion followed by 32p-labelling in vitro at their 5'-ends. ASBV is much smaller than potato spindle tuber viroid (PSTV; 359 residues) and chrysanthemum stunt viroid (CSV; 356 residues). A secondary structure model for ASBV is proposed and contains 67% of its residues base paired. In contrast to the extensive (69%) sequence homology of CSV with PSTV, only 18% of the ASBV sequence is homologous to PSTV and CSV. There are eight potential polypeptide translation products with chain lengths from 4 to 63 amino acid residues coded for by the plus (infectious) strand and four potential translation products (2 to 60 residues) coded for by the minus strand. An improved method is described for the synthesis of gamma-32p-ATP of high specific activity. PMID:7322921

  20. Numerically stable fluid–structure interactions between compressible flow and solid structures

    Grétarsson, Jón Tómas


    We propose a novel method to implicitly two-way couple Eulerian compressible flow to volumetric Lagrangian solids. The method works for both deformable and rigid solids and for arbitrary equations of state. The method exploits the formulation of [11] which solves compressible fluid in a semi-implicit manner, solving for the advection part explicitly and then correcting the intermediate state to time tn+1 using an implicit pressure, obtained by solving a modified Poisson system. Similar to previous fluid-structure interaction methods, we apply pressure forces to the solid and enforce a velocity boundary condition on the fluid in order to satisfy a no-slip constraint. Unlike previous methods, however, we apply these coupled interactions implicitly by adding the constraint to the pressure system and combining it with any implicit solid forces in order to obtain a strongly coupled, symmetric indefinite system (similar to [17], which only handles incompressible flow). We also show that, under a few reasonable assumptions, this system can be made symmetric positive-definite by following the methodology of [16]. Because our method handles the fluid-structure interactions implicitly, we avoid introducing any new time step restrictions and obtain stable results even for high density-to-mass ratios, where explicit methods struggle or fail. We exactly conserve momentum and kinetic energy (thermal fluid-structure interactions are not considered) at the fluid-structure interface, and hence naturally handle highly non-linear phenomenon such as shocks, contacts and rarefactions. © 2011 Elsevier Inc.

  1. Investigation on the near-wake flow structures of a utility-scale wind turbine using snowflake based flow visualization

    Dasari, Teja; Toloui, Mostafa; Guala, Michele; Hong, Jiarong


    Super-large-scale particle image velocimetry and flow visualization techniques using natural snow particles have been shown as an effective tool to probe the structure of the flow around full-scale wind turbines (Hong et al. Nature Comm. 2014). Here we present a follow-up study based on the data collected during a deployment around the 2.5 MW wind turbine at EOLOS Wind Energy Research Station on April, 4th, 2014. The dataset includes the snow visualization of flow fields from different perspectives in the near wake of the turbine. The motions of the dominant coherent structures including tip, blade root, hub and tower vortices, represented by the snow voids, are examined with the objective of quantifying and correlating their behavior with the meteorological and turbine operating conditions. Some preliminary studies on flow-structure interaction are also performed by correlating the data from strain gauges, accelerometers mounted on the turbine blades, with the flow measurements. The statistical analysis of the motions of blade induced vortices shows a clear impact of atmospheric turbulence and vortex interaction on flow development in the near wake. The result further indicates a strong connection between near-wake vorticity field, turbine operation and structure deformations. The work was supported by National Science Foundation (NSF-CBET-1454259) and the research infrastructure was supported by Department of Energy.

  2. Protein Primary Structure of the Vaccinia Virion at Increased Resolution

    Ngo, Tuan; Mirzakhanyan, Yeva; Moussatche, Nissin; Gershon, Paul David


    Here we examine the protein covalent structure of the vaccinia virus virion. Within two virion preparations, >88% of the theoretical vaccinia virus-encoded proteome was detected with high confidence, including the first detection of products from 27 open reading frames (ORFs) previously designated "predicted," "uncharacterized," "inferred," or "hypothetical" polypeptides containing as few as 39 amino acids (aa) and six proteins whose detection required nontryptic proteolysis. We also detected the expression of four short ORFs, each of which was located within an ORF ("ORF-within-ORF"), including one not previously recognized or known to be expressed. Using quantitative mass spectrometry (MS), between 58 and 74 proteins were determined to be packaged. A total of 63 host proteins were also identified as candidates for packaging. Evidence is provided that some portion of virion proteins are "nicked" via a combination of endoproteolysis and concerted exoproteolysis in a manner, and at sites, independent of virus origin or laboratory procedures. The size of the characterized virion phosphoproteome was doubled from 189 (J. Matson, W. Chou, T. Ngo, and P. D. Gershon, Virology 452-453:310-323, 2014, doi: to 396 confident, unique phosphorylation sites, 268 of which were within the packaged proteome. This included the unambiguous identification of phosphorylation "hot spots" within virion proteins. Using isotopically enriched ATP, 23 sites of intravirion kinase phosphorylation were detected within nine virion proteins, all at sites already partially occupied within the virion preparations. The clear phosphorylation of proteins RAP94 and RP19 was consistent with the roles of these proteins in intravirion early gene transcription. In a blind search for protein modifications, cysteine glutathionylation and O-linked glycosylation featured prominently. We provide evidence for the phosphoglycosylation of vaccinia virus proteins.

  3. Experiment on the Effect of Sediment Concentration on Flow Structure


    The paper studies on the sediment-laden flow by using MicroADV.Laboratory calibration has been conducted to determine the relationship between backscattered signal strength and sediment concentration. Based on the experimental data,the interactions between sediment and fluid in open channel flow are investi- gated.The experiment shows that there exist inner relation between sediment concentration and turbulence, and the relationship is distinctry related to the diameter of particle as well as the flow co...

  4. Identification of dominant flow structures in rapidly rotating convection of liquid metals using Dynamic Mode Decomposition

    Horn, S.; Schmid, P. J.; Aurnou, J. M.


    The Earth's metal core acts as a dynamo whose efficiency in generating and maintaining the magnetic field is essentially determined by the rotation rate and the convective motions occurring in its outer liquid part. For the description of the primary physics in the outer core the idealized system of rotating Rayleigh-Bénard convection is often invoked, with the majority of studies considering only working fluids with Prandtl numbers of Pr ≳ 1. However, liquid metals are characterized by distinctly smaller Prandtl numbers which in turn result in an inherently different type of convection. Here, we will present results from direct numerical simulations of rapidly rotating convection in a fluid with Pr ≈ 0.025 in cylindrical containers and Ekman numbers as low as 5 × 10-6. In this system, the Coriolis force is the source of two types of inertial modes, the so-called wall modes, that also exist at moderate Prandtl numbers, and cylinder-filling oscillatory modes, that are a unique feature of small Prandtl number convection. The obtained flow fields were analyzed using the Dynamic Mode Decomposition (DMD). This technique allows to extract and identify the structures that govern the dynamics of the system as well as their corresponding frequencies. We have investigated both the regime where the flow is purely oscillatory and the regime where wall modes and oscillatory modes co-exist. In the purely oscillatory regime, high and low frequency oscillatory modes characterize the flow. When both types of modes are present, the DMD reveals that the wall-attached modes dominate the flow dynamics. They precess with a relatively low frequency in retrograde direction. Nonetheless, also in this case, high frequency oscillations have a significant contribution.

  5. Speed-Flow Analysis for Interrupted Oversaturated Traffic Flow with Heterogeneous Structure for Urban Roads

    Hemant Kumar Sharma


    Full Text Available Speed–flow functions have been developed by several transportation experts to predict accurately the speed of urban road network. HCM Speed-Flow Curve, BPR Curve, MTC Speed-Flow Curve, Akçelik Speed-Flow Curve are some extraordinary efforts to define the shape of speed-flow curve. However, the complexity of driver’s behaviour, interactions among different type of vehicles, lateral clearance, co-relation of driver’s psychology with vehicular characteristics and interdependence of various variables of traffic has led to continuous development and refinement of speed-flow curves. The problem gets more tedious in case of urban roads with heterogeneous traffic, oversaturated flow and signalized network (which includes some unsignalized intersections as well. This paper presents speed-flow analysis for urban roads with interrupted flow comprising of heterogeneous traffic. Model has been developed for heterogeneous traffic under constraints of roadway geometry, vehicle characteristics, driving behaviour and traffic controls. The model developed in this paper shall predict speed, delay, average queue and maximum queue estimates for urban roads and quantify congestion for oversaturated condition. The investigation details oversaturated portion of flow in particular.

  6. Flow structure and flow-induced noise in an axisymmetric cavity with lids

    Jung, Seo Yoon [KAERI, Daejeon (Korea, Republic of); Sung, Hyung Jin [KAIST, Daejeon (Korea, Republic of)


    Direct numerical simulations of incompressible turbulent flow through an axisymmetric cavity with or without lids were performed at Re{sub t},{sub in} = 186 to examine the hydrodynamic effects of the lids on the flow-induced noise. The strength of the recirculation in the downstream region was weakened by the installation of the lids. Comparison of the acoustic sources of the Lighthill equation indicated that the lid in the downstream region attenuated the flow-induced noise substantially. Frequency spectra and spatio-temporal correlations of pressure fluctuations revealed the most energetic mode and the convective nature of the flow over the cavity. It was evident from a detailed investigation of the instantaneous flow fields that the introduction of lids into the cavity significantly weakened the interaction between the separated shear layer and the trailing edge of the cavity. The present results clearly showed that the installation of lids is an effective means of reducing flow-induced noise.

  7. Coupling Analysis of Fluid-Structure Interaction and Flow Erosion of Gas-Solid Flow in Elbow Pipe

    Hongjun Zhu; Hongnan Zhao; Qian Pan; Xue Li


    A numerical simulation has been conducted to investigate flow erosion and pipe deformation of elbow in gas-solid two-phase flow. The motion of the continuous fluid phase is captured based on calculating three-dimensional Reynolds-averaged-Navier-Stokes (RANS) equations, while the kinematics and trajectory of the discrete particles are evaluated by discrete phase model (DPM), and a fluid-structure interaction (FSI) computational model is adopted to calculate the pipe deformation. The effects o...

  8. The present-day heat flow structure of Mars

    Parro, L. M.; Jiménez-Díaz, A.; Mansilla, F.; Ruiz, J.


    Until the arrival of in-situ measurements, the study of the current heat flow of Mars goes through indirect methods, mainly based on the relation between the thermal state of lithosphere and their mechanical strength, or on theoretical models of internal evolution. Here, we present a first-order global model for the present-day surface heat flow for Mars, based on the current radiogenic heat production of the crust and mantle, scaling heat flow variations arising from crustal thickness and topography crustal thickness variations, and on the heat flow derived from the effective elastic thickness of the lithosphere beneath the North Polar Region. Our preferred model find heat flows varying between 14 and 23 mW m-2, with an average value of 18.6 mW m-2. Similar results are obtained if we use heat flow based on the lithosphere strength of the South Polar Region. Moreover, expressing our results in terms of the Urey ratio (the ratio between total internal heat production and heat loss), we have values close to 0.8, which indicates a moderate contribution of secular cooling to the heat flow of Mars (consistent with low heat flow values deduced from lithosphere strength), unless that heat-producing elements abundances for Mars are subchondritics.

  9. Flow-induced vibration of circular cylindrical structures

    Chen, S.S.


    This report summarizes the flow-induced vibration of circular cylinders in quiescent fluid, axial flow, and crossflow, and applications of the analytical methods and experimental data in design evaluation of various system components consisting of circular cylinders. 219 figs., 30 tabs. (JDB)

  10. Analysis of the flow structure and heat transfer in a vertical mantle heat exchanger

    Knudsen, Søren; Morrison, GL; Behnia, M


    initially mixed and initially stratified inner tank and mantle. The analysis of the heat transfer showed that the flow in the mantle near the inlet is mixed convection flow and that the heat transfer is dependent on the mantle inlet temperature relative to the core tank temperature at the mantle level. (C......The flow structure inside the inner tank and inside the mantle of a vertical mantle heat exchanger was investigated using a full-scale tank designed to facilitate flow visualisation. The flow structure and velocities in the inner tank and in the mantle were measured using a Particle Image...... Velocimetry (PIV) system. A Computational Fluid Dynamics (CFD) model of the vertical mantle heat exchanger was also developed for a detailed evaluation of the heat flux at the mantle wall and at the tank wall. The flow structure was evaluated for both high and low temperature incoming flows and for both...


    SU Li; LI Shu-juan; TANG Guo-an


    The fluid flow induced by light-density, low-stiffness structures was treated as inviscid, incompressible irrotational and steady plane flow. On the basis of the dipole configuration method, a singularity distribution method of distributing sources/sinks and dipoles on interfaces of the structure and fluid was developed to solve the problem of fluid flow induced by the vibration of common structures, such as columns and columns with fins,deduce the expression of kinetic energy of the fluid flow, and obtain the added mass finally.The calculational instances with analytical solutions prove the reliability of this method.

  12. Structure and Mixing Characterization of Variable Density Transverse Jet Flows

    Gevorkyan, Levon

    (CVP) and the generation of strong upstream shear layer instability. In contrast, weak, convectively unstable upstream shear layers corresponded with asymmetries in the jet cross-sectional shape and/or lack of a CVP structure. While momentum flux ratio J and density ratio S most significantly determined the strength of the instabilities and CVP structures, an additional dependence on jet Reynolds number for CVP formation was found, with significant increases in jet Reynolds number resulting in enhanced symmetry and CVP generation. The mixing characteristics of Rej = 1900 jets of various J, S, and injector type were explored in detail in the present studies using jet centerplane and cross-sectional PLIF measurements. Various mixing metrics such as the jet fluid centerline concentration decay, Unmixedness, and Probability Density Function (PDF) were applied systematically using a novel method for comparing jets with different mass flux characteristics. It was found that when comparing mixing metrics along the jet trajectory, strengthening the upstream shear layer instability by reducing J, and achieving absolutely unstable conditions, enhanced overall mixing. Reducing density ratio S for larger J values, which under equidensity (S = 1.00) conditions would create a convectively unstable shear layer, was also observed to enhance mixing. On the other hand, reducing S for low J conditions, which are known to produce absolutely unstable upstream shear layers even for equidensity cases, was actually observed to reduce mixing, a result attributed to a reduction in crossfiow fluid entrainment into shear layer vortex cores as jet density was reduced. Comparing injectors, the flush-mounted pipe was generally the best mixer, whereas the worst mixer was the nozzle that was elevated above the crossfiow boundary layer due to upstream shear layer co-flow generated by the elevated nozzle contour; this co-flow was observed here and in prior studies to stabilize the shear layer. The

  13. The Tip Leakage Flow Structure of an Axial Fan with Tip Clearance

    竺晓程; 杜朝辉; 林万来


    Experiment and numerical simulation technique are used to investigate the tip leakage flow in an axial fanwith tip clearance at the design condition. The flow field in the tip region of fan is measured using a PDA (ParticleDynamics Analysis) system. The flow is surveyed across the whole passage at fifteen axial locations (from the100% axial chord in front of the leading edge to the 100% axial chord behind the trailing edge), mainly focusing onthe outer 90% blade span. Both experiment measurement and numerical simulation indicates the leakage flow orig-inated from the tip clearance along the chord rolls-up into three-dimensional spiral structure to form leakage flowvortex. The interaction of leakage flow and main flow will produce the low velocity zone, and block the flow. Theleakage flow almost occupies the most part of flow passage behind the trailing edge.

  14. Performance improvement of IPMC flow sensors with a biologically-inspired cupula structure

    Lei, Hong; Sharif, Montassar Aidi; Paley, Derek A.; McHenry, Matthew J.; Tan, Xiaobo


    Ionic polymer-metal composites (IPMCs) have inherent underwater sensing and actuation properties. They can be used as sensors to collect flow information. Inspired by the hair-cell mediated receptor in the lateral line system of fish, the impact of a flexible, cupula-like structure on the performance of IPMC flow sensors is experimentally explored. The fabrication method to create a silicone-capped IPMC sensor is reported. Experiments are conducted to compare the sensing performance of the IPMC flow sensor before and after the PDMS coating under the periodic flow stimulus generated by a dipole source in still water and the laminar flow stimulus generated in a flow tank. Experimental results show that the performance of IPMC flow sensors is significantly improved under the stimulus of both periodic flow and laminar flow by the proposed silicone-capping.

  15. Rare gas flow structuration in plasma jet experiments

    Robert, E.; Sarron, V.; Darny, T.; Riès, D.; Dozias, S.; Fontane, J.; Joly, L.; Pouvesle, J.-M.


    Modifications of rare gas flow by plasma generated with a plasma gun (PG) are evidenced through simultaneous time-resolved ICCD imaging and schlieren visualization. The geometrical features of the capillary inside which plasma propagates before in-air expansion, the pulse repetition rate and the presence of a metallic target are playing a key role on the rare gas flow at the outlet of the capillary when the plasma is switched on. In addition to the previously reported upstream offset of the laminar to turbulent transition, we document the reverse action leading to the generation of long plumes at moderate gas flow rates together with the channeling of helium flow under various discharge conditions. For higher gas flow rates, in the l min-1 range, time-resolved diagnostics performed during the first tens of ms after the PG is turned on, evidence that the plasma plume does not start expanding in a laminar neutral gas flow. Instead, plasma ignition leads to a gradual laminar-like flow build-up inside which the plasma plume is generated. The impact of such phenomena for gas delivery on targets mimicking biological samples is emphasized, as well as their consequences on the production and diagnostics of reactive species.

  16. Structured Process Energy-Exergy-Flow Diagram and Ideality Index for Analysis of Energy Transformation in Chemical Processes (Part 1)

    Hiroshi OAKI; Masaru ISHIDA; Tsuneo IKAWA


      A new diagram called structured process energy-exergy-flow diagram (SPEED) is proposed to systematically analyze the structure of energy flow in chemical processes and to design the process structures effectively...

  17. Structure-Function Correlations using Scanning Laser Polarimetry in Primary Angle-Closure Glaucoma and Primary Open Angle Glaucoma

    Lee, Pei-Jung; Liu, Catherine Jui-Ling.; Wojciechowski, Robert; Bailey-Wilson, Joan E.; Cheng, Ching-Yu


    Purpose To assess the correlations between retinal nerve fiber layer (RNFL) thickness measured with scanning laser polarimetry (SLP) and visual field (VF) sensitivity in primary open angle glaucoma (POAG) and primary angle-closure glaucoma (PACG). Design Prospective, comparative, observational cases series Methods Fifty patients with POAG and 56 with PACG were examined using SLP with variable corneal compensation (GDx VCC) and Humphrey VF analyzer between August 2005 and July 2006 at Taipei Veterans General Hospital. Correlations between RNFL thickness and VF sensitivity, expressed as mean sensitivity (MS) in both decibel (dB) and 1/Lambert (L) scales, were estimated by Spearman's rank correlation coefficient (rs) and multivariate median regression models (pseudo R2). The correlations were determined globally and for six RNFL sectors and their corresponding VF regions. Results The correlation between RNFL thickness and MS (in dB) was weaker in the PACG group (rs = 0.38, P = 0.004, pseudo R2 = 0.17) than in the POAG group (rs = 0.51, P <0.001, pseudo R2 = 0.31), but the difference in the magnitude of correlation was not significant (P = 0.42).With Bonferroni correction, the structure-function correlation was significant in the superotemporal (rs = 0.62), superonasal (rs = 0.56), inferonasal (rs = 0.53), and inferotemporal (rs = 0.50) sectors in the POAG group (all P <0.001), while it was significant only in the superotemporal (rs = 0.53) and inferotemporal (rs = 0.48) sectors in the PACG group (both P <0.001). The results were similar when MS was expressed as 1/L scale. Conclusions Both POAG and PACG eyes had moderate structure-function correlations using SLP. Compared to eyes with POAG, fewer RNFL sectors have significant structure-function correlations in eyes with PACG. PMID:20202618

  18. Flow structures and sandbar dynamics in a canyon river during a controlled flood, Colorado River, Arizona

    Wright, S.A.; Kaplinski, M.


    In canyon rivers, debris fan constrictions create rapids and downstream pools characterized by secondary flow structures that are closely linked to channel morphology. In this paper we describe detailed measurements of the three-dimensional flow structure and sandbar dynamics of two pools along the Colorado River in the Grand Canyon during a controlled flood release from Glen Canyon Dam. Results indicate that the pools are characterized by large lateral recirculation zones (eddies) resulting from flow separation downstream from the channel constrictions, as well as helical flow structures in the main channel and eddy. The lateral recirculation zones are low-velocity areas conducive to fine sediment deposition, particularly in the vicinity of the separation and reattachment points and are thus the dominant flow structures controlling sandbar dynamics. The helical flow structures also affect morphology but appear secondary in importance to the lateral eddies. During the controlled flood, sandbars in the separation and reattachment zones at both sites tended to build gradually during the rising limb and peak flow. Deposition in shallow water on the sandbars was accompanied by erosion in deeper water along the sandbar slope at the interface with the main channel. Erosion occurred via rapid mass failures as well as by gradual boundary shear stress driven processes. The flow structures and morphologic links at our study sites are similar to those identified in other river environments, in particular sharply curved meanders and channel confluences where the coexistence of lateral recirculation and helical flows has been documented. Copyright 2011 by the American Geophysical Union.

  19. Structure and kinematics of bubble flow; Structure et cinematique des ecoulements diphasiques a bulles

    Lackme, C. [Commissariat a l' Energie Atomique, Grenoble (France). Centre d' Etudes Nucleaires


    This report deals with the components and use of resistivity probes in bubble flow. With a single probe, we have studied the longitudinal and radial structure of the flow. The very complicated evolution of the radial structure is shown by the measurement of the mean bubble flux at several points in the tube. A double probe associated with a device the principle of which is given in this report, permits the measure of the local velocity of bubbles. Unlike the mean bubble flux profile, the change in the velocity profile along the tube is not significant. We have achieved the synthesis of these two pieces of information, mean local bubble flux and local velocity, by computing the mean weighed velocity in the tube. This weighed velocity compares remarkably with the velocity computed from the volumetric gas flow rate and the mean void fraction. (author) [French] Ce rapport traite d'une etude methodologique des ecoulements diphasiques a bulles. Les fluides sont l'air et l'eau, ils circulent du bas vers le haut dans un tube vertical de 32 mm de diametre et 2 metres de long. Cette etude a pour but de permettre une description fine de l'ecoulement. Pour cela, il a ete necessaire de developper des appareillages nouveaux et de mettre au point les methodes d'analyses correspondantes. La valeur des mesures effectuees et des methodes utilisees apparait dans une comparaison concluante et conclusive entre des resultats de mesures globales et des resultats integres de mesures locales. (auteur)

  20. Macroscopic effects of the spectral structure in turbulent flows

    Tran, T.; Chakraborty, P.; Guttenberg, N.; Prescott, A.; Kellay, H.; Goldburg, W.; Goldenfeld, N.; Gioia, G.


    There is a missing link between macroscopic properties of turbulent flows, such as the frictional drag of a wall-bounded flow, and the turbulent spectrum. To seek the missing link we carry out unprecedented experimental measurements of the frictional drag in turbulent soap-film flows over smooth walls. These flows are effectively two-dimensional, and we are able to create soap-film flows with the two types of turbulent spectrum that are theoretically possible in two dimensions: the "enstrophy cascade," for which the spectral exponent α= 3, and the "inverse energy cascade," for which the spectral exponent α= 5/3. We find that the functional relation between the frictional drag f and the Reynolds number Re depends on the spectral exponent: where α= 3, f ˜Re-1/2; where α= 5/3, f ˜Re-1/4. Each of these scalings may be predicted from the attendant value of α by using a recently proposed spectral theory of the frictional drag. In this theory the frictional drag of turbulent flows on smooth walls is predicted to be f ˜Re^(1-α)/(1+α).

  1. The Effects of Vortex Generator Types on Heat Transfer and Flow Structure in a Rectangular Duct Flows

    Laith J.H


    Full Text Available In this numerical study a detailed evaluation of the heat transfer characteristics and flow structure in a laminar and turbulent flow through a rectangular channel containing built-in of different type vortex generator has been a accomplished in a range of Reynolds number between 500 and 100,000.A modified version of ESCEAT code has been used to solve Navier-Stokes and energy equations. The purpose of this paper is to present numerical comparisons in terms of temperature, Nusselt number and flow patterns on several configurations of longitudinal vortex generator including new five cases. The structures of heat and flow were studied, using iso-contours of velocity components, vortices, temperature and Nusselt number. This study shows that the predicted structures of fluid flow, temperature fields and Nusselt number variation are strongly affected by the presence of the turbulators. Staggered arrangement gains high Nusselt number, also the lower and upper arrangements have higher Nusselt number than plane duct. High Reynolds number (higher air inlet velocity will enhance the Nusselt number. Increase in ribs height will enhance the heat transfer as it works as surface area and turbulator at the same time.

  2. Structure-function correlations using scanning laser polarimetry in primary angle-closure glaucoma and primary open-angle glaucoma.

    Lee, Pei-Jung; Liu, Catherine Jui-Ling; Wojciechowski, Robert; Bailey-Wilson, Joan E; Cheng, Ching-Yu


    To assess the correlations between retinal nerve fiber layer (RNFL) thickness measured with scanning laser polarimetry and visual field (VF) sensitivity in primary open-angle glaucoma (POAG) and primary angle-closure glaucoma (PACG). Prospective, comparative, observational cases series. Fifty patients with POAG and 56 patients with PACG were examined using scanning laser polarimetry with variable corneal compensation (GDx VCC; Laser Diagnostic Technologies, Inc.) and Humphrey VF analyzer (Carl Zeiss Meditec, Inc.) between August 2005 and July 2006 at Taipei Veterans General Hospital. Correlations between RNFL thickness and VF sensitivity, expressed as mean sensitivity in both decibel and 1/Lambert scales, were estimated by the Spearman rank correlation coefficient (r(s)) and multivariate median regression models (pseudo R(2)). The correlations were determined globally and for 6 RNFL sectors and their corresponding VF regions. The correlation between RNFL thickness and mean sensitivity (in decibels) was weaker in the PACG group (r(s) = 0.38; P = .004; pseudo R(2) = 0.17) than in the POAG group (r(s) = 0.51; P polarimetry. Compared with eyes with POAG, fewer RNFL sectors have significant structure-function correlations in eyes with PACG. Copyright 2010 Elsevier Inc. All rights reserved.

  3. Topology Method for Analyses of 3—D Viscous Flow Structure in Transonic Turbomachinery

    YanhuGuo; BaoguoWang; 等


    A topology method is presented in this paper to reveal flow tructure occurring insie turbomachinery,in which near wall flow structure is revealed by using wall limiting streamilines and space flow feature is revealed by using space streamilines and cross-section streamlines,As an example ,a computational three-dimensional viscous flow field inside a transonic turbine cascade is studied.Through the analysis,the form and evolution of vortex system and the whole process of separation occurring within this cascade are revealed.The application of topology method for analyze flow structure inside turbomachinmery is very important for understanding flow features and mechanism of flow loss even for improving the design of turbomachinery and increasing its efficiency.

  4. Primary acoustic signal structure during free falling drop collision with a water surface

    Chashechkin, Yu. D., E-mail:; Prokhorov, V. E., E-mail: [Russian Academy of Sciences, Ishlinskii Institute for Problems in Mechanics (Russian Federation)


    Consistent optical and acoustic techniques have been used to study the structure of hydrodynamic disturbances and acoustic signals generated as a free falling drop penetrates water. The relationship between the structures of hydrodynamic and acoustic perturbations arising as a result of a falling drop contacting with the water surface and subsequent immersion into water is traced. The primary acoustic signal is characterized, in addition to stably reproduced features (steep leading edge followed by long decay with local pressure maxima), by irregular high-frequency packets, which are studied for the first time. Reproducible experimental data are used to recognize constant and variable components of the primary acoustic signal.

  5. An optical fiber Fabry-Perot flow measurement technology based on partial bend structure

    Yang, Huijia; Jiang, Junfeng; Zhang, Xuezhi; Pan, Yuheng; Zhu, Wanshan; Zhou, Xiang; Liu, Tiegen


    An optical fiber Fabry-Perot (F-P) flow measurement technology is presented, which is based on partial bend structure. A 90° partial bend structure is designed to achieve the non-probe flow measurement with a pressure difference. The fluid simulation results of partial bend structure show that the error of the pressure difference is below 0.05 kPa during steady flow. The optical fiber F-P sensor mounted on the elbow with pressure test accuracy of 1% full scale is used to measure the fluid flow. Flow test results show that when the flow varies from 1 m3/h to 6.5 m3/h at ambient temperature of 25 °C, the response time is 1 s and the flow test accuracy is 4.5% of the F-P flow test system, proving that the F-P flow test method based on partial bend structure can be used in fluid flow measurement.

  6. Simulation and Assessment of Whole Life-Cycle Carbon Emission Flows from Different Residential Structures

    Rikun Wen


    Full Text Available To explore the differences in carbon emissions over the whole life-cycle of different building structures, the published calculated carbon emissions from residential buildings in China and abroad were normalized. Embodied carbon emission flows, operations stage carbon emission flows, demolition and reclamation stage carbon emission flows and total life-cycle carbon emission flows from concrete, steel, and wood structures were obtained. This study is based on the theory of the social cost of carbon, with an adequately demonstrated social cost of carbon and social discount rate. Taking into consideration both static and dynamic situations and using a social discount rate of 3.5%, the total life-cycle carbon emission flows, absolute carbon emission and building carbon costs were calculated and assessed. The results indicated that concrete structures had the highest embodied carbon emission flows and negative carbon emission flows in the waste and reclamation stage. Wood structures that started the life-cycle with stored carbon had the lowest carbon emission flows in the operations stage and relatively high negative carbon emission flows in the reclamation stage. Wood structures present the smallest carbon footprints for residential buildings.

  7. Visualization and research of gas-liquid two phase flow structures in cylindrical channel

    Stefański Sebastian


    Full Text Available Two-phase flows are commonly found in many industries, especially in systems, where efficient and correct functioning depend on specific values of flow parameters. In thermal engineering and chemical technology the most popular types of two-phase mixture are gas-liquid or liquid-vapour mixtures. Bubbles can create in flow different structures and determine diverse properties of flow (velocity of phase, void fraction, fluctuations of pressure, pipe vibrations, etc.. That type of flow is difficult to observe, especially in liquid-vapour mixture, where vapour is being made by heating the medium. Production of vapour and nucleation process are very complicated issues, which are important part of two-phase flow phenomenon. Gas-liquid flow structures were observed and described with figures, but type of structure depends on many parameters. Authors of this paper made an attempt to simulate gas-liquid flow with air and water. In the paper there was presented specific test stand built to observe two-phase flow structures, methodology of experiment and conditions which were maintained during observation. The paper presents also the structures which were observed and the analysis of results with reference to theoretical models and diagrams available in literature.

  8. An Immersed Boundary Finite-Element Solver for Flow-Induced Deformation of Soft Structures with Application in Cardiac Flows

    Bhardwaj, Rajneesh; Mittal, Rajat


    The modeling of complex biological phenomena such as cardiac mechanics is challenging. It involves complex three dimensional geometries, moving structure boundaries inside the fluid domain and large flow-induced deformations of the structure. We present a fluid-structure interaction solver (FSI) which couples a sharp-interface immersed boundary method for flow simulation with a powerful finite-element based structure dynamics solver. An implicit partitioned (or segregated) approach is implemented to ensure the stability of the solver. We validate the FSI solver with published benchmark for a configuration which involves a thin elastic plate attached to a rigid cylinder. The frequency and amplitude of the oscillations of the plate are in good agreement with published results and non-linear dynamics of the plate and its coupling with the flow field are discussed. The FSI solver is used to understand left-ventricular hemodynamics and flow-induced dynamics of mitral leaflets during early diastolic filling and results from this study are presented.

  9. Biphasic flow: structure and upscaling, consequences on macroscopic transport properties

    Toussaint, Renaud; Méheust, Yves; Løvoll, Grunde; Jankov, Mihailo; Schäfer, Gerhard; Schmittbuhl, Jean


    In disordered porous media, two-phase flow of immiscible fluids (biphasic flow) is organized in patterns that sometimes exhibit fractal geometries over a range of length scales, depending on the capillary, gravitational and viscous forces at play. These forces, as well as the boundary conditions, also determine whether the flow leads to the appearance of fingering pathways, i.e., unstable flow, or not. We present here a short review of these aspects, focusing on drainage and summarizing when these flows are expected to be stable or not, what fractal dimensions can be expected, and in which range of scales. We base our review on experimental studies performed in two-dimensional Hele-Shaw cells, or addressing three dimensional porous media by use of several imaging techniques. We first present configurations in which solely capillary forces and gravity play a role. Next, we review configurations in which capillarity and viscosity are the main forces at play. Eventually, we examine how the microscopic geometry o...

  10. Gas dilution system using critical flow Venturi nozzles for generating primary trace-moisture standards in multiple gas species

    Amano, Minami; Abe, Hisashi


    Gas dilution systems are commonly used to generate calibration gas mixtures for secondary gas standards. However, if a gas dilution system is used to generate gas mixtures for primary trace-moisture standards in multiple gas species, difficulty arises; flow control with relative stability of better than 0.009% is required although the relative uncertainty of the best gas flow meter to date is around 0.3%. In this study, we developed a novel gas dilution system using critical flow Venturi nozzles to address this problem. The developed dilution system can measure and control the flow rates of gases in the range of approximately 0.05 l min-1 to 7 l min-1 (when converted to those measured at 101 325 Pa and 273.15 K) with relative stability of better than 0.007%. Using the dilution system, we developed a magnetic suspension balance/diffusion-tube humidity generator capable of generating trace moisture in N2 in the range of approximately 10 nmol mol-1 to 5 µmol mol-1 in amount fraction. The accuracy of the generated trace-moisture standard was verified by measurement with cavity ring-down spectroscopy.

  11. Can perfusion CT assessment of primary colorectal adenocarcinoma blood flow at staging predict for subsequent metastatic disease? A pilot study

    Goh, Vicky [Mount Vernon Hospital, Paul Strickland Scanner Centre, Northwood (United Kingdom); Halligan, Steve [University College Hospital, Department of Academic Radiology, London (United Kingdom); Wellsted, David M. [University of Hertfordshire, Health Research and Development Support Unit, Hatfield (United Kingdom); Bartram, Clive I. [St Mark' s Hospital, Intestinal Imaging Centre, Harrow (United Kingdom)


    We aimed to determine whether perfusion CT measurements at colorectal cancer staging may predict for subsequent metastatic relapse. Fifty two prospective patients underwent perfusion CT at staging to estimate tumour blood flow, blood volume, mean transit time, and permeability surface area product. Patients considered metastasis free and suitable for surgery underwent curative resection subsequently. At final analysis, a median of 48.6 months post-surgery, patients were divided into those who remained disease free, and those with subsequent metastases. Vascular parameters for these two groups were compared using t-testing, and receiver operator curve analysis was performed to determine the sensitivity and specificity of these vascular parameters for predicting metastases. Thirty seven (71%) patients underwent curative surgery; data were available for 35: 26 (74%) remained disease free; 9 (26%) recurred (8 metastatic, 1 local). Tumour blood flow differed significantly between disease-free and metastatic patients (76.0 versus 45.7 ml/min/100 g tissue; p=0.008). With blood flow <64 ml/min/100 g tissue, sensitivity and specificity (95% CI) for development of metastases were 100% (60-100%) and 73% (53-87%), respectively. Our preliminary findings suggest that primary tumour blood flow might potentially be a useful predictor warranting further study. (orig.)

  12. Structural and contextual dimensions of Iranian primary health care system at local level.

    Zanganeh Baygi, Mehdi; Seyedin, Hesam; Salehi, Masoud; Jafari Sirizi, Mehdi


    In recent years, family physician plan was established as the main strategy of health system in Iran, while organizational structure of the primary health care system has remained the same as thirty years ago. This study was performed to illustrate structural and contextual dimensions of organizational structure and relationship between them in Iranian primary health care system at local level. A cross-sectional quantitative study was conducted from January to June 2013, during which 121 questionnaires were distributed among senior and junior managers of city health centers at Medical Sciences universities in Iran. Validity of the questionnaire was confirmed by experts (CVI = 0.089 and CVR more than 0.85) and Cronbach α was utilized for reliability (α = 0.904). We used multistage sampling method in this study and analysis of the data was performed by SPSS software using different tests. Local level of primary health care system in Iran had mechanical structure, but in contextual dimensions the results showed different types. There was a significant relationship between structural and contextual dimensions (r = 0.642, P value structural dimensions. Because of the changes in goals and strategies of Iranian health system in recent years, it is urgently recommended to reform the current structure to increase efficiency and effectiveness of the system.

  13. Flow-Induced Deformation of a Flexible Thin Structure as Manifestation of Heat Transfer Enhancement

    Soti, Atul Kumar; Sheridan, John


    Flow-induced deformation of thin structures coupled with convective heat transfer has potential applications in energy harvesting and is important for understanding functioning of several biological systems. We numerically demonstrate large-scale flow-induced deformation as an effective passive heat transfer enhancement technique. An in-house, strongly-coupled fluid-structure interaction (FSI) solver is employed in which flow and structure solvers are based on sharp-interface immersed boundary and finite element method, respectively. In the present work, we validate convective heat transfer module of the in-house FSI solver against several benchmark examples of conduction and convective heat transfer including moving structure boundaries. The thermal augmentation is investigated as well as quantified for the flow-induced deformation of an elastic thin plate attached to lee side of a rigid cylinder in a heated channel laminar flow. We show that the wake vortices past the plate sweep higher sources of vorticity...

  14. Spontaneous gene flow and population structure in wild and cultivated chicory, Cichorium intybus L

    Kiær, Lars Pødenphant; Felber, F.; Flavell, A.;


    Spontaneous gene flow between wild and cultivated chicory, Cichorium intybus L., may have implications for the genetic structure and evolution of populations and varieties. One aspect of this crop-wild gene flow is the dispersal of transgenes from genetically modified varieties, e.g. gene flow from...... and Mediterranean Europe. The analysis used 281 AFLP markers and 75 SSAP markers giving a total of 356 polymorphic markers. Results from model based assignments with the program STRUCTURE indicated many incidents of recent gene flow. Gene flow was observed both between cultivars and wild populations, between...... landraces and wild populations, between different wild populations as well as between cultivars. Population structure visualized by distance-based clustering showed a North–South geographical structuring of the wild populations, and a general grouping of the cultivars corresponding to known origin...

  15. Three-dimensional (3D) printing of mouse primary hepatocytes to generate 3D hepatic structure

    Kim, Yohan; Kang, Kyojin; Jeong, Jaemin; Paik, Seung Sam; Kim, Ji Sook; Park, Su A; Kim, Wan Doo; Park, Jisun


    Purpose The major problem in producing artificial livers is that primary hepatocytes cannot be cultured for many days. Recently, 3-dimensional (3D) printing technology draws attention and this technology regarded as a useful tool for current cell biology. By using the 3D bio-printing, these problems can be resolved. Methods To generate 3D bio-printed structures (25 mm × 25 mm), cells-alginate constructs were fabricated by 3D bio-printing system. Mouse primary hepatocytes were isolated from the livers of 6–8 weeks old mice by a 2-step collagenase method. Samples of 4 × 107 hepatocytes with 80%–90% viability were printed with 3% alginate solution, and cultured with well-defined culture medium for primary hepatocytes. To confirm functional ability of hepatocytes cultured on 3D alginate scaffold, we conducted quantitative real-time polymerase chain reaction and immunofluorescence with hepatic marker genes. Results Isolated primary hepatocytes were printed with alginate. The 3D printed hepatocytes remained alive for 14 days. Gene expression levels of Albumin, HNF-4α and Foxa3 were gradually increased in the 3D structures. Immunofluorescence analysis showed that the primary hepatocytes produced hepatic-specific proteins over the same period of time. Conclusion Our research indicates that 3D bio-printing technique can be used for long-term culture of primary hepatocytes. It can therefore be used for drug screening and as a potential method of producing artificial livers. PMID:28203553

  16. Three-dimensional (3D) printing of mouse primary hepatocytes to generate 3D hepatic structure.

    Kim, Yohan; Kang, Kyojin; Jeong, Jaemin; Paik, Seung Sam; Kim, Ji Sook; Park, Su A; Kim, Wan Doo; Park, Jisun; Choi, Dongho


    The major problem in producing artificial livers is that primary hepatocytes cannot be cultured for many days. Recently, 3-dimensional (3D) printing technology draws attention and this technology regarded as a useful tool for current cell biology. By using the 3D bio-printing, these problems can be resolved. To generate 3D bio-printed structures (25 mm × 25 mm), cells-alginate constructs were fabricated by 3D bio-printing system. Mouse primary hepatocytes were isolated from the livers of 6-8 weeks old mice by a 2-step collagenase method. Samples of 4 × 10(7) hepatocytes with 80%-90% viability were printed with 3% alginate solution, and cultured with well-defined culture medium for primary hepatocytes. To confirm functional ability of hepatocytes cultured on 3D alginate scaffold, we conducted quantitative real-time polymerase chain reaction and immunofluorescence with hepatic marker genes. Isolated primary hepatocytes were printed with alginate. The 3D printed hepatocytes remained alive for 14 days. Gene expression levels of Albumin, HNF-4α and Foxa3 were gradually increased in the 3D structures. Immunofluorescence analysis showed that the primary hepatocytes produced hepatic-specific proteins over the same period of time. Our research indicates that 3D bio-printing technique can be used for long-term culture of primary hepatocytes. It can therefore be used for drug screening and as a potential method of producing artificial livers.

  17. Structure parameters in rotating Couette-Poiseuille channel flow

    Knightly, George H.; Sather, D.


    It is well-known that a number of steady state problems in fluid mechanics involving systems of nonlinear partial differential equations can be reduced to the problem of solving a single operator equation of the form: v + lambda Av + lambda B(v) = 0, v is the summation of H, lambda is the summation of one-dimensional Euclid space, where H is an appropriate (real or complex) Hilbert space. Here lambda is a typical load parameter, e.g., the Reynolds number, A is a linear operator, and B is a quadratic operator generated by a bilinear form. In this setting many bifurcation and stability results for problems were obtained. A rotating Couette-Poiseuille channel flow was studied, and it showed that, in general, the superposition of a Poiseuille flow on a rotating Couette channel flow is destabilizing.

  18. Coherent Structures near Narrow Gaps in Channel Flows

    Guellouz, M. S.; Tavoularis, S.


    Flow visualization and hot-wire anemometry were used to investigate the velocity field in axial flow within a rectangular channel containing a single cylindrical rod, parallel to the channel's axis and positioned at different distances from the wall. The formation of a street of three-dimensional, quasi-periodic, counter-rotating vortices in the vicinity of the gap has been observed, even for relatively large gaps. The Strouhal number, convection speed and streamwise spacing of these vortices have been determined as functions of the gap size and the flow parameters. A useful feature of these vortices is the large-scale transport of fluid across the gap, which enhances momentum, heat and mass transfer.

  19. Speed and structure of turbulent fronts in pipe flow

    Song, Baofang; Hof, Björn; Avila, Marc


    The dynamics of laminar-turbulent fronts in pipe flow is investigated for Reynolds numbers between Re=1900 and Re=5500 using extensive direct numerical simulations. In this range the flow undergoes a continuous transition from localised puffs to weakly expanding and ultimately to strongly expanding turbulent slugs (Barkley et al. 2015). We here investigate the physical distinction between these two types of slug by analysing time-resolved statistics of their downstream fronts in the frame moving at the bulk turbulent advection speed. While weak fronts travel slower than the bulk turbulent advection speed, implying local relaminarisation, strong fronts travel faster and so feed on the laminar flow ahead. At Re$\\approx$2900 the downstream front speed becomes faster than the advection speed, marking the onset of strong fronts. We argue that large temporal fluctuations of production and dissipation at the laminar-turbulent interface drive the dynamical switches between the two types of front observed up to Re$\\si...

  20. Thousands of corresponding human and mouse genomic regions unalignable in primary sequence contain common RNA structure

    Torarinsson, Elfar; Sawera, Milena; Havgaard, Jakob Hull


    been investigated. Owing to the limitations in computational methods, comparative genomics has been lacking the ability to compare such nonconserved sequence regions for conserved structural RNA elements. We have investigated the presence of structural RNA elements by conducting a local structural...... alignment, using FOLDALIGN, on a subset of these 100,000 corresponding regions and estimate that 1800 contain common RNA structures. Comparing our results with the recent mapping of transcribed fragments (transfrags) in human, we find that high-scoring candidates are twice as likely to be found in regions...... expressed non-coding RNA sequences not alignable in primary sequence....

  1. A Debris-flow Simulation Model for the Evaluation of Protection Structures


    Debris flow is the flow of a solid-fluid mixture and in this investigation it is treated as the flow of a continuum in routing. A numerical model is proposed describing debris flow including erosion and deposition processes with suitable boundary conditions. The numerical model is applied to evaluate the effects of protection structures against debris flow caused by heavy rainfall on the Shen-Mu Stream of Nantou County located in central Taiwan. Simulation results indicated that the proposed model can offer useful pre-planning guidelines for engineers.

  2. Structure and work process in primary care and hospitalizations for sensitive conditions

    Waleska Regina Machado Araujo


    Full Text Available ABSTRACT OBJECTIVE The objective of this study is to investigate whether the characteristics of the structure of primary health units and the work process of primary care teams are associated with the number of hospitalizations for primary care sensitive conditions. METHODS In this ecological study, we have analyzed data of Brazilian municipalities related to sociodemographic characteristics, coverage of care programs, structure of primary health units, and work process of primary care teams. We have obtained the data from the first cycle of the Brazilian Program for Improving Access and Quality of the Primary Care, of the Department of Information Technology of the Brazilian Unified Health System, the Brazilian Institute of Geography and Statistics, and the United Nations Development Programme. The associations have been estimated using negative binomial regression coefficients (β and respective 95% confidence intervals, with a hierarchical approach in three levels (alpha = 5%. RESULTS In the adjusted analysis for the outcome in 2013, in the distal level, the coverage of the Bolsa Família Program (β = -0.001 and private insurance (β = -0.01 had a negative association, and the human development index (β = 1.13, the proportion of older adults (β = 0.05 and children under the age of five (β = 0.05, and the coverage of the Community Health Agent Strategy (β = 0.002 showed positive association with hospitalizations for primary care sensitive conditions. In the intermediate level, minimum hours (β = -0.14 and availability of vaccines (β = -0.16 showed a negative association, and availability of medications showed a positive association (β = 0.16. In the proximal level, only the variable of matrix support (β = 0.10 showed a positive association. The variables in the adjusted analysis of the number of hospitalizations for primary care sensitive conditions in 2014 presented the same association as in 2013. CONCLUSIONS The characteristics of

  3. Groundwater Flow Systems at the Nevada Test Site, Nevada: A Synthesis of Potentiometric Contours, Hydrostratigraphy, and Geologic Structures

    Fenelon, Joseph M.; Sweetkind, Donald S.; Laczniak, Randell J.


    Contaminants introduced into the subsurface of the Nevada Test Site by underground nuclear testing are of concern to the U.S. Department of Energy and regulators responsible for protecting human health and safety. The potential for contaminant movement away from the underground test areas and into the accessible environment is greatest by groundwater transport. The primary hydrologic control on this transport is evaluated and examined through a series of contour maps developed to represent the hydraulic-head distribution within each of the major aquifers underlying the area. Aquifers were identified and their extents delineated by merging and analyzing multiple hydrostratigraphic framework models developed by other investigators from existing geologic information. A map of the hydraulic-head distribution in each major aquifer was developed from a detailed evaluation and assessment of available water-level measurements. Multiple spreadsheets that accompany this report provide pertinent water-level and geologic data by well or drill hole. Aquifers are mapped and discussed in general terms as being one of two types: alluvial-volcanic, or carbonate. Both aquifer types are subdivided and mapped as independent regional and local aquifers, based on the continuity of their component rock. Groundwater-flow directions, approximated from potentiometric contours that were developed from the hydraulic-head distribution, are indicated on the maps and discussed for each of the regional aquifers and for selected local aquifers. Hydraulic heads vary across the study area and are interpreted to range in altitude from greater than 5,000 feet in a regional alluvial-volcanic aquifer beneath a recharge area in the northern part of the study area to less than 2,300 feet in regional alluvial-volcanic and carbonate aquifers in the southwestern part of the study area. Flow directions throughout the study area are dominantly south-southwest with some local deviations. Vertical hydraulic

  4. Structural Arrangement Trade Study. Volume 1: Reusable Hydrogen Composite Tank System (RHCTS) and Graphite Composite Primary Structures (GCPS). Executive summary


    This volume is the first of a three volume set that discusses the structural arrangement trade study plan that will identify the most suitable configuration for an SSTO winged vehicle capable of delivering 25,000 lbs to a 220 nm circular orbit at 51.6 deg inclination. The Reusable Hydrogen Composite Tank System (RHCTS), and Graphite Composite Primary Structures most suitable for intertank, wing and thrust structures are identified. This executive summary presents the trade study process, the selection process, requirements used, analysis performed and data generated. Conclusions and recommendations are also presented.

  5. A water tunnel flow visualization study of the vortex flow structures on the F/A-18 aircraft

    Sandlin, Doral R.; Ramirez, Edgar J.


    The vortex flow structures occurring on the F/A-18 aircraft at high angles of attack were studied. A water tunnel was used to gather flow visualization data on the forebody vortex and the wing leading edge extension vortex. The longitudinal location of breakdown of the leading edge vortex was found to be consistently dependent on the angle of attack. Other parameters such as Reynolds number, model scale, and model fidelity had little influence on the overall behavior of the flow structures studied. The lateral location of the forebody vortex system was greatly influenced by changes in the angle of sideslip. Strong interactions can occur between the leading edge extension vortex and the forebody vortex. Close attention was paid to vortex induced flows on various airframe components of the F/A-18. Reynolds number and angle of attack greatly affected the swirling intensity, and therefore the strength of the studied vortices. Water tunnel results on the F/A-18 correlated well with those obtained in similar studies at both full and sub scale levels. The water tunnel can provide, under certain conditions, good simulations of realistic flows in full scale configurations.

  6. Emissivity corrected infrared method for imaging anomalous structural heat flows

    Del Grande, Nancy K.; Durbin, Philip F.; Dolan, Kenneth W.; Perkins, Dwight E.


    A method for detecting flaws in structures using dual band infrared radiation. Heat is applied to the structure being evaluated. The structure is scanned for two different wavelengths and data obtained in the form of images. Images are used to remove clutter to form a corrected image. The existence and nature of a flaw is determined by investigating a variety of features.

  7. Code Flows : Visualizing Structural Evolution of Source Code

    Telea, Alexandru; Auber, David


    Understanding detailed changes done to source code is of great importance in software maintenance. We present Code Flows, a method to visualize the evolution of source code geared to the understanding of fine and mid-level scale changes across several file versions. We enhance an existing visual met

  8. Code flows : Visualizing structural evolution of source code

    Telea, Alexandru; Auber, David


    Understanding detailed changes done to source code is of great importance in software maintenance. We present Code Flows, a method to visualize the evolution of source code geared to the understanding of fine and mid-level scale changes across several file versions. We enhance an existing visual met

  9. Propulsion of micro-structures in Oscillatory Stokes Flow

    Jo, Ikhee; Huang, Yangyang; Zimmerman, Walter; Kanso, Eva


    Drug delivery often necessitates specific site-targeting within the human body. The use of micro and/or nano devices swimming through the bloodstream provides an attractive mechanism for targeted drug targeting, however the design and practical implementation of such devices remain very challenging. Inspired by flapping wings, we construct a two-dimensional wedge-like device, consisting of two links connected by a linear torsional spring and released in an oscillatory Stokes flow. We vary the stiffness and rest angle of the linear spring and the oscillation amplitude and frequency of the background flow to explore the behavior of the device. We find that the device achieves a net displacement, or propulsion, in oscillatory flows even when no elastic energy is stored initially, thus breaking Purcell's scallop's theorem. More importantly, the vehicle tends to align with the background flow under perturbations. We conclude by commenting on how to control the parameters of the device and the fluid to achieve desired behavior of the device. These findings may have significant implications on the design of micro devices in viscous fluids.

  10. Control of Low Reynolds Number Flows with Fluid Structure Interactions


    public release; distribution is unlimited. 27 the direct numerical simulations of Andro and Jacquin [37] for a plunging NACA 0012 airfoil at Re...34Bifurcating Flows of Plunging Airfoils at High Strouhal Numbers," Journal of Fluid Mechanics, Vol. 708, 2012, pp. 349-376. [37] Andro , J.Y

  11. The Effectiveness of Structured Co-Operative Teaching and Learning in Greek Primary School Classrooms

    Kaldi, Stavroula; Filippatou, Diamanto; Anthopoulou, Barbara


    This study focuses upon the effectiveness of structured co-operative group work on primary school students, aged between 8.5 and 9.5 years old, regarding their content knowledge, attitudes towards co-operative group work, experiential learning and open-ended curriculum as well as students' social and learning behaviour during co-operative group…

  12. The Effectiveness of Structured Co-Operative Teaching and Learning in Greek Primary School Classrooms

    Kaldi, Stavroula; Filippatou, Diamanto; Anthopoulou, Barbara


    This study focuses upon the effectiveness of structured co-operative group work on primary school students, aged between 8.5 and 9.5 years old, regarding their content knowledge, attitudes towards co-operative group work, experiential learning and open-ended curriculum as well as students' social and learning behaviour during co-operative group…

  13. An Improbable Leadership: Structural Limits of Educational Communication. The Case of Some Italian Primary Schools

    Farini, Federico


    This paper discusses the results of field research focused on educational communication in the classroom. The research involved 11 primary schools in Italy. Nearly 100 hours of videotaped educational interactions were produced. The empirical analysis of the communication processes allowed us to analyse the main structures of educational…

  14. Asymmetrical reverse vortex flow due to induced-charge electro-osmosis around carbon stacking structures

    Sugioka, Hideyuki


    Broken symmetry of vortices due to induced-charge electro-osmosis (ICEO) around stacking structures is important for the generation of a large net flow in a microchannel. Following theoretical predictions in our previous study, we herein report experimental observations of asymmetrical reverse vortex flows around stacking structures of carbon posts with a large height (~110 μm) in water, prepared by the pyrolysis of a photoresist film in a reducing gas. Further, by the use of a coupled calculation method that considers boundary effects precisely, the experimental results, except for the problem of anomalous flow reversal, are successfully explained. That is, unlike previous predictions, the precise calculations here show that stacking structures accelerate a reverse flow rather than suppressing it for a microfluidic channel because of the deformation of electric fields near the stacking portions; these structures can also generate a large net flow theoretically in the direction opposite that of a previous prediction for a standard vortex flow. Furthermore, by solving the one-dimensional Poisson-Nernst-Plank (PNP) equations in the presence of ac electric fields, we find that the anomalous flow reversal occurs by the phase retardation between the induced diffuse charge and the tangential electric field. In addition, we successfully explain the nonlinearity of the flow velocity on the applied voltage by the PNP analysis. In the future, we expect to improve the pumping performance significantly by using stacking structures of conductive posts along with a low-cost process.

  15. Persistent retrograde flow structures at high latitudes - extent in depth and time

    Baldner, Charles; Bogart, Richard S.


    Medium resolution helioseismic studies of the near-surface layers of the Sun have revealed the existence of coherent retrograde flow structures that persist for multiple solar rotations (Bogart et al. 2015). Similar surface features have been detected and suggested to be related to giant cell convection (Hathaway et al. 2013). These structures seem to be confined to high latitudes (greater than 60°N/S) and are have magnitudes (relative to the mean solar flow) of less than 1 m s-1. In this work we extend our earlier analysis of these flow structures by studying their extent and structure in depth and their evolution in time. In particular, we attempt to determine the depth at which the anomalous flow structures are most significant, and to determine their migration relative to the Carrington coordinate frame.

  16. Large eddy simulation of a buoyancy-aided flow in a non-uniform channel – Buoyancy effects on large flow structures

    Duan, Y. [Department of Mechanical Engineering, University of Sheffield, Sheffield S1 3JD (United Kingdom); School of Mechanical, Aerospace and Civil Engineering, University of Manchester, Manchester M13 9PL (United Kingdom); He, S., E-mail: [Department of Mechanical Engineering, University of Sheffield, Sheffield S1 3JD (United Kingdom)


    Highlights: • Buoyancy may greatly redistribute the flow in a non-uniform channel. • Flow structures in the narrow gap are greatly changed when buoyancy is strong. • Large flow structures exist in wider gap, which is enhanced when heat is strong. • Buoyancy reduces mixing factor caused by large flow structures in narrow gap. - Abstract: It has been a long time since the ‘abnormal’ turbulent intensity distribution and high inter-sub-channel mixing rates were observed in the vicinity of the narrow gaps formed by the fuel rods in nuclear reactors. The extraordinary flow behaviour was first described as periodic flow structures by Hooper and Rehme (1984). Since then, the existences of large flow structures were demonstrated by many researchers in various non-uniform flow channels. It has been proved by many authors that the Strouhal number of the flow structure in the isothermal flow is dependent on the size of the narrow gap, not the Reynolds number once it is sufficiently large. This paper reports a numerical investigation on the effect of buoyancy on the large flow structures. A buoyancy-aided flow in a tightly-packed rod-bundle-like channel is modelled using large eddy simulation (LES) together with the Boussinesq approximation. The behaviour of the large flow structures in the gaps of the flow passage are studied using instantaneous flow fields, spectrum analysis and correlation analysis. It is found that the non-uniform buoyancy force in the cross section of the flow channel may greatly redistribute the velocity field once the overall buoyancy force is sufficiently strong, and consequently modify the large flow structures. The temporal and axial spatial scales of the large flow structures are influenced by buoyancy in a way similar to that turbulence is influenced. These scales reduce when the flow is laminarised, but start increasing in the turbulence regeneration region. The spanwise scale of the flow structures in the narrow gap remains more or

  17. Biomimetic structures for fluid drag reduction in laminar and turbulent flows

    Jung, Yong Chae; Bhushan, Bharat, E-mail: Bhushan.2@osu.ed [Nanoprobe Laboratory for Bio- and Nanotechnology and Biomimetics (NLB2), Ohio State University, 201 West 19th Avenue, Columbus, OH 43210-1142 (United States)


    Biomimetics allows one to mimic nature to develop materials and devices of commercial interest for engineers. Drag reduction in fluid flow is one of the examples found in nature. In this study, nano, micro, and hierarchical structures found in lotus plant surfaces, as well as shark skin replica and a rib patterned surface to simulate shark skin structure were fabricated. Drag reduction efficiency studies on the surfaces were systematically carried out using water flow. An experimental flow channel was used to measure the pressure drop in laminar and turbulent flows, and the trends were explained in terms of the measured and predicted values by using fluid dynamics models. The slip length for various surfaces in laminar flow was also investigated based on the measured pressure drop. For comparison, the pressure drop for various surfaces was also measured using air flow.

  18. Imaging of the Space-time Structure of a Vortex Generator in Supersonic Flow

    WANG Dengpan; XIA Zhixun; ZHAO Yuxin; WANG Bo; ZHAO Yanhui


    The fine space-time structure of a vortex generator (VG) in supersonic flow is studied with the nanoparticle-based planar laser scattering (NPLS) method in a quiet supersonic wind tunnel.The fine coherent structure at the symmetrical plane of the flow field around the VG is imaged with NPLS.The spatial structure and temporal evolution characteristics of the vortical structure are analyzed,which demonstrate periodic evolution and similar geometry,and the characteristics of rapid movement and slow change.Because the NPLS system yields the flow images at high temporal and spatial resolutions,from these images the position of a large scale structure can be extracted precisely.The position and velocity of the large scale structures can be evaluated with edge detection and correlation algorithms.The shocklet structures induced by vortices are imaged,from which the generation and development of shocklets are discussed in this paper.

  19. Two-phase flow interfacial structures in a rod bundle geometry

    Paranjape, Sidharth S.

    Interfacial structure of air-water two-phase flow in a scaled nuclear reactor rod bundle geometry was studied in this research. Global and local flow regimes were obtained for the rod bundle geometry. Local two-phase flow parameters were measured at various axial locations in order to understand the transport of interfacial structures. A one-dimensional two-group interfacial area transport model was evaluated using the local parameter database. Air-water two-phase flow experiments were performed in an 8 X 8 rod bundle test section to obtain flow regime maps at various axial locations. Area averaged void fraction was measured using parallel plate type impedance void meters. The cumulative probability distribution functions of the signals from the impedance void meters were used along with a self organizing neural network to identify flow regimes. Local flow regime maps revealed the cross-sectional distribution of flow regimes in the bundle. Local parameters that characterize interfacial structure, that is, void fraction alpha, interfacial area concentration, ai, bubble Sauter mean diameter, DSm and bubble velocity, vg were measured using four sensor conductivity probe technique. The local data revealed the distribution of the interfacial structure in the radial direction, as well as its development in the axial direction. In addition to this, the effect of spacer grid on the flow structure at different gas and liquid velocities was revealed by local parameter measurements across the spacer grids. A two-group interfacial area transport equation (IATE) specific to rod bundle geometry was derived. The derivation of two-group IATE required certain assumption on the bubble shapes in the subchannels and the bubbles spanning more than a subchannel. It was found that the geometrical relationship between the volume and the area of a cap bubble distorted by rods was similar to the one derived for a confined channel under a specific geometrical transformation. The one

  20. Free-surface flow simulations for discharge-based operation of hydraulic structure gates

    Erdbrink, C D; Sloot, P M A


    We combine non-hydrostatic flow simulations of the free surface with a discharge model based on elementary gate flow equations for decision support in operation of hydraulic structure gates. A water level-based gate control used in most of today's general practice does not take into account the fact that gate operation scenarios producing similar total discharged volumes and similar water levels may have different local flow characteristics. Accurate and timely prediction of local flow conditions around hydraulic gates is important for several aspects of structure management: ecology, scour, flow-induced gate vibrations and waterway navigation. The modelling approach is described and tested for a multi-gate sluice structure regulating discharge from a river to the sea. The number of opened gates is varied and the discharge is stabilized with automated control by varying gate openings. The free-surface model was validated for discharge showing a correlation coefficient of 0.994 compared to experimental data. A...

  1. Effect of volumetric electromagnetic forces on shock wave structure of hypersonic air flow near plate

    Fomichev, Vladislav; Yadrenkin, Mikhail; Shipko, Evgeny


    Summarizing of experimental studies results of the local MHD-interaction at hypersonic air flow near the plate is presented. Pulsed and radiofrequency discharge have been used for the flow ionization. It is shown that MHD-effect on the shock-wave structure of the flow is significant at test conditions. Using of MHD-interaction parameter enabled to defining characteristic modes of MHD-interaction by the force effect: weak, moderate and strong.

  2. Bandwidth turbulence control based on flow community structure in the Internet

    Wu, Xiaoyu; Gu, Rentao; Ji, Yuefeng


    Bursty flows vary rapidly in short period of time, and cause fierce bandwidth turbulence in the Internet. In this letter, we model the flow bandwidth turbulence process by constructing a flow interaction network (FIN network), with nodes representing flows and edges denoting bandwidth interactions among them. To restrain the bandwidth turbulence in FIN networks, an immune control strategy based on flow community structure is proposed. Flows in community boundary positions are immunized to cut off the inter-community turbulence spreading. By applying this control strategy in the first- and the second-level flow communities separately, 97.2% flows can effectively avoid bandwidth variations by immunizing 21% flows, and the average bandwidth variation degree reaches near zero. To achieve a similar result, about 70%-90% immune flows are needed with targeted control strategy based on flow degrees and random control strategy. Moreover, simulation results showed that the control effect of the proposed strategy improves significantly if the immune flow number is relatively smaller in each control step.

  3. Flow Structures and Energy Capture from an Oscillating Hydrofoil

    Franck, Jennifer; Frank, Sarah; Mandre, Shreyas


    The flow surrounding an oscillating hydrofoil in a uniform freestream is computationally investigated for hydrokinetic energy capture. Simulations are performed on an elliptical hydrofoil using 2D Direct Numerical Simulation (DNS) for low Reynolds number and 3D Large-Eddy Simulations (LES) for high Reynolds number simulations at 80,000. A non-inertial reference frame is utilized for rigid-body motion of the hydrofoil, which is prescribed a sinusoidal motion in pitch and heave. The kinematic parameters are varied and the resulting flow features are correlated with positive or negative energy capture. In an effort to optimize the stroke, variations in the sinusoidal heave and pitch signals are systematically explored and analyzed for future closed-loop control.


    Dong Zhi-yong


    The compressible characteristics in aerated flows at the high velocity of about 50m/s were analyzed. Based on the theory of compressible the relations between the sonic speed and shock wave in high-velocity aerated flow were theoretically deduced. And comparisons with measured data were made. The theoretical and experimental results show the sonic speed in aerated flow is merely of the order of several-dozen meters per second, and its minimum value is only 20m/s, which is far much less than that in water or air alone. So high subsonic flow, supersonic flow and transonic flow as well as compression wave, shock wave and expansion wave similarly to aerodnamics may be produced in high velocity aerated flow at the speed of the order of 50m/s. Hence the influences of these compressible characteristics on high head discharge structures can not be neglected, especially on super high dams over 200m high.

  5. Force and Flow Structure of an Airfoil Performing Some

    Sun; Mao; Hossein; Hamdani


    0 Introduction  Insects use their wings to provide lifting Propulsive and control for ces for the flight.for these prrposes the wings must frequently change direction.speed and orientation .Therefore unsteddy flow effects are of great importance[1].As a result in recent years.unsteddy aerodynamics of insect flight received much attention(e.g.[2][3]).……

  6. Improved Flow-Field Structures for Direct Methanol Fuel Cells

    Gurau, Bogdan


    The direct methanol fuel cell (DMFC) is ideal if high energy-density liquid fuels are required. Liquid fuels have advantages over compressed hydrogen including higher energy density and ease of handling. Although state-of-the-art DMFCs exhibit manageable degradation rates, excessive fuel crossover diminishes system energy and power density. Although use of dilute methanol mitigates crossover, the concomitant lowering of the gross fuel energy density (GFED) demands a complex balance-of-plant (BOP) that includes higher flow rates, external exhaust recirculation, etc. An alternative approach is redesign of the fuel delivery system to accommodate concentrated methanol. NuVant Systems Inc. (NuVant) will maximize the GFED by design and assembly of a DMFC that uses near neat methanol. The approach is to tune the diffusion of highly concentrated methanol (to the anode catalytic layer) to the back-diffusion of water formed at the cathode (i.e. in situ generation of dilute methanol at the anode layer). Crossover will be minimized without compromising the GFED by innovative integration of the anode flow-field and the diffusion layer. The integrated flow-field-diffusion-layers (IFDLs) will widen the current and potential DMFC operating ranges and enable the use of cathodes optimized for hydrogen-air fuel cells.

  7. Metallic and Non-Metallic Materials for the Primary Support Structure

    RA Wolf; RP Corson


    The primary support structure (PSS) is required for mechanical support of reactor module (RM) components and mounting of the RM to the spacecraft. The PSS would provide support and accept all loads associated with dynamic (e. g., launch and maneuvering) or thermally induced loading. Prior to termination of NRPCT involvement in Project Prometheus, the NRPCT Mechanical Systems team developed preliminary finite element models to gain a basic understanding of the behavior of the structure, but optimization of the models, specification of the final design, and materials selection were not completed. The Space Plant Materials team had evaluated several materials for potential use in the primary support structure, namely titanium alloys, beryllium, aluminum alloys and carbon-carbon composites. The feasibility of application of each material system was compared based on mass, stiffness, thermal expansion, and ease of fabrication. Due to insufficient data on environmental factors, such as temperatures and radiation, and limited modeling support, a final materials selection was not made.

  8. Primary Structure and Mechanical Properties of AlSi2 Alloy Continuous Ingots

    Wróbel T.


    Full Text Available The paper presents the research results of horizontal continuous casting of ingots of aluminium alloy containing 2% wt. silicon (AlSi2. Together with the casting velocity (velocity of ingot movement we considered the influence of electromagnetic stirring in the area of the continuous casting mould on refinement of the ingot’s primary structure and their selected mechanical properties, i.e. tensile strength, yield strength, hardness and elongation. The effect of primary structure refinement and mechanical properties obtained by electromagnetic stirring was compared with refinement obtained by using traditional inoculation, which consists in introducing additives, i.e. Ti, B and Sr, to the metal bath. On the basis of the obtained results we confirmed that inoculation done by electromagnetic stirring in the range of the continuous casting mould guarantees improved mechanical properties and also decreases the negative influence of casting velocity, thus increasing the structure of AlSi2 continuous ingots.

  9. Viscoelastic fluid-structure interaction between a non-Newtonian fluid flow and flexible cylinder

    Dey, Anita; Modarres-Sadeghi, Yahya; Rothstein, Jonathan


    It is well known that when a flexible or flexibly-mounted structure is placed perpendicular to the flow of a Newtonian fluid, it can oscillate due to the shedding of separated vortices at high Reynolds numbers. If the same flexible object is placed in non-Newtonian flows, however, the structure's response is still unknown. Unlike Newtonian fluids, the flow of viscoelastic fluids can become unstable at infinitesimal Reynolds numbers due to a purely elastic flow instability. In this talk, we will present a series of experiments investigating the response of a flexible cylinder placed in the cross flow of a viscoelastic fluid. The elastic flow instabilities occurring at high Weissenberg numbers can exert fluctuating forces on the flexible cylinder thus leading to nonlinear periodic oscillations of the flexible structure. These oscillations are found to be coupled to the time-dependent state of viscoelastic stresses in the wake of the flexible cylinder. The static and dynamic responses of the flexible cylinder will be presented over a range of flow velocities, along with measurements of velocity profiles and flow-induced birefringence, in order to quantify the time variation of the flow field and the state of stress in the fluid.

  10. Structural proteins of the primary cell wall: extraction, purification, and analysis.

    Lamport, Derek T A; Tan, Li; Kieliszewski, Marcia J


    Structural proteins of the primary cell wall present unusual but interesting problems for structural biologists in particular and plant biologists in general. As structure is the key to function; then the biochemical isolation of these glycoproteins for further study is paramount. Here, we detail the "classical" method for isolating soluble extensin monomers by elution of monomeric precursors to network extensin from tissue cultures. We also outline an additional approach involving genetic engineering that can potentially yield the complete genomic range of extensins and other hydroxyproline-rich glycoprotein (HRGPs) currently underutilized for biotechnology.

  11. Vortical Structures and Turbulent Bursts Behind Magnetic Obstacles in Transitional Flow Regimes

    Kenjeres, S.; Ten Cate, S.; Voesenek, C.J.


    The present paper reports on numerical investigations of vortical structures in transient flow regimes generated by the local action of the Lorentz force on an electrically conductive fluid. The locally imposed non-uniform magnetic field generates similar effects as observed for flows over submerged

  12. Three-dimensional evolution of flow structures in transitional circular and chevron jets

    Violato, D.; Scarano, F.


    The three-dimensional behavior of flow transition in circular and 6-chevron jets at Re = 5000 is investigated with experiments conducted on a free water jet by time-resolved tomographic particle image velocimetry. The emphasis is on the unsteady organization of coherent flow structures, which play a

  13. Three-dimensional evolution of flow structures in transitional circular and chevron jets

    Violato, D.; Scarano, F.


    The three-dimensional behavior of flow transition in circular and 6-chevron jets at Re = 5000 is investigated with experiments conducted on a free water jet by time-resolved tomographic particle image velocimetry. The emphasis is on the unsteady organization of coherent flow structures, which play a

  14. Spontaneous gene flow and population structure in wild and cultivated chicory, Cichorium intybus L

    Kiær, Lars Pødenphant; Felber, F.; Flavell, A.


    and Mediterranean Europe. The analysis used 281 AFLP markers and 75 SSAP markers giving a total of 356 polymorphic markers. Results from model based assignments with the program STRUCTURE indicated many incidents of recent gene flow. Gene flow was observed both between cultivars and wild populations, between...

  15. POD analysis of flow structures in a scale model of a ventilated room

    Pedersen, Jakob Martin; Meyer, Knud Erik


    Measurements with particle image velocimetry have been carried out in a scale model of the Annex 20 room. Data were taken in a plane near the inlet. The flow consisted of a wall jet (Re=5,000) and a low-velocity region below the jet. POD was used to analyze dominant flow structures. The analysis...

  16. The effects of flow on schooling Devario aequipinnatus: school structure, startle response and information transmission.

    Chicoli, A; Butail, S; Lun, Y; Bak-Coleman, J; Coombs, S; Paley, D A


    To assess how flow affects school structure and threat detection, startle response rates of solitary and small groups of giant danio Devario aequipinnatus to visual looming stimuli were compared in flow and no-flow conditions. The instantaneous position and heading of each D. aequipinnatus was extracted from high-speed videos. Behavioural results indicate that (1) school structure is altered in flow such that D. aequipinnatus orient upstream while spanning out in a crosswise direction, (2) the probability of at least one D. aequipinnatus detecting the visual looming stimulus is higher in flow than no flow for both solitary D. aequipinnatus and groups of eight D. aequipinnatus; however, (3) the probability of three or more individuals responding is higher in no flow than in flow. These results indicate a higher probability of stimulus detection in flow but a higher probability of internal transmission of information in no flow. Finally, results were well predicted by a computational model of collective fright response that included the probability of direct detection (based on signal detection theory) and indirect detection (i.e. via interactions between group members) of threatening stimuli. This model provides a new theoretical framework for analysing the collective transfer of information among groups of fishes and other organisms.

  17. Manipulating Heat Flow through 3 Dimensional Nanoscale Phononic Crystal Structure


    SUBJECT TERMS phonon transport , Thermoelectric, nano structures, nano photonics 16. SECURITY CLASSIFICATION OF: 17. LIMITATION OF ABSTRACT Same as...conductivity is also studied. 15. SUBJECT TERMS phonon transport , Thermoelectric, nano structures, nano photonics 16. SECURITY CLASSIFICATION OF: 17...but not yet published L-N Yang, J Chen, N Yang, and B Li, Manipulating Graphene Thermal Conductivity by Phononic

  18. Ratiometric analysis of fura red by flow cytometry: a technique for monitoring intracellular calcium flux in primary cell subsets.

    Emily R Wendt

    Full Text Available Calcium flux is a rapid and sensitive measure of cell activation whose utility could be enhanced with better techniques for data extraction. We describe a technique to monitor calcium flux by flow cytometry, measuring Fura Red calcium dye by ratiometric analysis. This technique has several advantages: 1 using a single calcium dye provides an additional channel for surface marker characterization, 2 allows robust detection of calcium flux by minority cell populations within a heterogeneous population of primary T cells and monocytes 3 can measure total calcium flux and additionally, the proportion of responding cells, 4 can be applied to studying the effects of drug treatment, simultaneously stimulating and monitoring untreated and drug treated cells. Using chemokine receptor activation as an example, we highlight the utility of this assay, demonstrating that only cells expressing a specific chemokine receptor are activated by cognate chemokine ligand. Furthermore, we describe a technique for simultaneously stimulating and monitoring calcium flux in vehicle and drug treated cells, demonstrating the effects of the Gαi inhibitor, pertussis toxin (PTX, on chemokine stimulated calcium flux. The described real time calcium flux assay provides a robust platform for characterizing cell activation within primary cells, and offers a more accurate technique for studying the effect of drug treatment on receptor activation in a heterogeneous population of primary cells.

  19. Deterministic modelling of the cumulative impacts of underground structures on urban groundwater flow and the definition of a potential state of urban groundwater flow: example of Lyon, France

    Attard, Guillaume; Rossier, Yvan; Winiarski, Thierry; Cuvillier, Loann; Eisenlohr, Laurent


    Underground structures have been shown to have a great influence on subsoil resources in urban aquifers. A methodology to assess the actual and the potential state of the groundwater flow in an urban area is proposed. The study develops a three-dimensional modeling approach to understand the cumulative impacts of underground infrastructures on urban groundwater flow, using a case in the city of Lyon (France). All known underground structures were integrated in the numerical model. Several simulations were run: the actual state of groundwater flow, the potential state of groundwater flow (without underground structures), an intermediate state (without impervious structures), and a transient simulation of the actual state of groundwater flow. The results show that underground structures fragment groundwater flow systems leading to a modification of the aquifer regime. For the case studied, the flow systems are shown to be stable over time with a transient simulation. Structures with drainage systems are shown to have a major impact on flow systems. The barrier effect of impervious structures was negligible because of the small hydraulic gradient of the area. The study demonstrates that the definition of a potential urban groundwater flow and the depiction of urban flow systems, which involves understanding the impact of underground structures, are important issues with respect to urban underground planning.


    QIU Xiang


    Turbulence structures and turbulent Counter-Gradient Transport(CGT) properties in the stratified flows with a sharp temperature interface are investigated by experimental measurements using LIF and PIV, by LES and by correlation analysis.

  1. Final Report - Investigation of Intermittent Turbulence and Turbulent Structures in the Presence of Controlled Sheared Flows

    Gilmore, Mark A. [University of New Mexico


    Final Report for grant DE-FG02-06ER54898. The dynamics and generation of intermittent plasma turbulent structures, widely known as "blobs" have been studied in the presence of sheared plasma flows in a controlled laboratory experiment.

  2. Thermal structure and flow patterns around Seychelles group of Islands (Indian Ocean) during austral autumn

    Vethamony, P.; RameshBabu, V.; RameshKumar, M.R.

    Properties of thermal structure in the upper 750 m around the Seychelles group of islands in the Indian Ocean, based on Expendable Bathythermograph (XBT) data collected in March 1984, are presented along with the inferred flow patterns...

  3. Direct numerical simulation of Taylor–Couette flow with grooved walls: torque scaling and flow structure

    Zhu, X.; Ostilla-Monico, Rodolfo; Verzicco, R.; Lohse, D.


    We present direct numerical simulations of Taylor–Couette flow with grooved walls at a fixed radius ratio ${\\it\\eta}=r_{i}/r_{o}=0.714$η=ri/ro=0.714 with inner cylinder Reynolds number up to $Re_{i}=3.76\\times 10^{4}$Rei=3.76×104, corresponding to Taylor number up to $Ta=2.15\\times 10^{9}$Ta=2.15×10

  4. Review: Impact of underground structures on the flow of urban groundwater

    Attard, Guillaume; Winiarski, Thierry; Rossier, Yvan; Eisenlohr, Laurent


    Property economics favours the vertical development of cities but flow of groundwater can be affected by the use of underground space in them. This review article presents the state of the art regarding the impact of disturbances caused by underground structures (tunnels, basements of buildings, deep foundations, etc.) on the groundwater flow in urban aquifers. The structures built in the underground levels of urban areas are presented and organised in terms of their impact on flow: obstacle to the flow or disturbance of the groundwater budget of the flow system. These two types of disturbance are described in relation to the structure area and the urban area. The work reviewed shows, on one hand, the individual impacts of different urban underground structures, and on the other, their cumulative impacts on flow, using real case studies. Lastly, the works are placed in perspective regarding the integration of underground structures with the aim of operational management of an urban aquifer. The literature presents deterministic numerical modelling as a tool capable of contributing to this aim, in that it helps to quantify the effect of an underground infrastructure project on groundwater flow, which is crucial for decision-making processes. It can also be an operational decision-aid tool for choosing construction techniques or for formulating strategies to manage the water resource.



    In this paper, the influence of surface roughness on flow structure was numerically studied.An adaptive numerical method, the fast vortex method was employed.A mathematical roughness, which comes from the no-slip condition of vortex method, was introduced.The numerical results indicate that the roughness has appreciable influence on the flow structure.The vortex shedding could be controlled if the forward multi-layer boundary condition is exerted.

  6. The late time structure of high density contrast, single mode Richtmyer-Meshkov flow

    Williams, R J R


    We study the late time flow structure of Richtmyer-Meshkov instability. Recent numerical work has suggested a self-similar collapse of the development of this instability at late times, independent of the initial surface profile. Using the form of collapse suggested, we derive an analytic expression for the mass-velocity relation in the spikes, and a global theory for the late time flow structure. We compare these results with fluid dynamical simulation.

  7. Particle-fluid-structure interaction for debris flow impact on flexible barriers

    A. Leonardi; Wittel, F. K.; Mendoza, M.; Vetter, R.; Herrmann, H.J.


    Flexible barriers are increasingly used for the protection from debris flow in mountainous terrain due to their low cost and environmental impact. However, a numerical tool for rational design of such structures is still missing. In this work, a hybrid computational framework is presented, using a total Lagrangian formulation of the Finite Element Method (FEM) to represent a flexible barrier. The actions exerted on the structure by a debris flow are obtained from simultaneous simulations of t...

  8. Cross flow induced vibrations in staggered arrays of cylindrical structures

    Marn, J.


    Flow induced vibrations cause by instability is the subject of this investigation. The bulk of the work performed is theoretical in nature, the comparison with some of existing experimental data is given for each of four models described. First model encompasses the effects of prescribed motion on the cylinder. Such circumstances occur in the case of vortex shedding initiated instability. The reduced velocity within the cylinder array is low and there is no coupling between the adjacent cylinders. Second model assumes certain form of vibration and corresponding behavior of the perturbed velocity field in temporal and one of spatial coordinates thus transforming partial differential equations into ordinary differential equations and takes into account the motion of the neighboring cylinder. This corresponds to fluid elastic controlled instabilities. The resulting equations are solved analytically. The model is used for better understanding of the equations of cylinder motion as well as for quick estimates of threshold of instability. Third model relaxes an assumption about the form of vibration in spatial direction and uses the vorticity formulation of equation of fluid motion to account for fluid-solid interaction. This model analysis is of two phase (air-water mixture) flow. The void fraction distribution is found to be the single most decisive factor to determine the onset of instability for such a domain. In conclusion, two distinct mechanism were found to be responsible for flow induced vibration caused instabilities, (1) outside source controlled periodic excitation (such as vortex shedding) -- described by the first model and (2) fluid elastic forces -- described by second, third and fourth models. For the values of reduced velocity below 0.7 first model is proposed, for the values above 0.7, the rest.

  9. Structure of Three-Dimensional Separated Flow on Symmetric Bumps


    calculated using N - tan(SSA) -ni(/W/iy) t (1 N- - = - --(4 1 )tan(F(;A) - UII /(LI/’) where vih and 17’- are the stream-wise and span-wise eddy...velocity vectors only in bimodal region and the black lines are connecting these vectors for visual aid . As expected, the two flow patterns are totally... aid only at different yi of. Figure 5.7 Normalized FrF + IWk- vectors locally tangent to surface. 5. LDV Measurements near Large Bump#3 Surface 160

  10. Bed Stability and Debris Flow Erosion: A Dynamic "Shields Criterion" Associated with Bed Structure

    Longjas, A.; Hill, K. M.


    Debris flows are mass movements that play an important role in transporting sediment from steep uplands to rivers at lower slopes. As the debris flow moves downstream, it entrains materials such as loose boulders, gravel, sand and mud deposited locally by shorter flows such as slides and rockfalls. To capture the conditions under which debris flows entrain bed sediment, some models use something akin to the Shields' criterion and an excess shear stress of the flow. However, these models typically neglect granular-scale effects in the bed which can modify the conditions under which a debris flow is erosional or depositional. For example, it is well known that repeated shearing causes denser packing in loose dry soils, which undoubtedly changes their resistance to shear. Here, we present laboratory flume experiments showing that the conditions for entrainment by debris flows is significantly dependent on the aging of an erodible bed even for narrowly distributed spherical particles. We investigate this quantitatively using particle tracking measurements to quantify instantaneous erosion rates and the evolving bed structure or "fabric". With progressive experiments we find a signature that emerges in the bed fabric that is correlated with an increasing apparent "fragility" of the bed. Specifically, a system that is originally depositional may become erosional after repeated debris flow events, and an erodible bed becomes increasingly erodible with repeated flows. We hypothesize that related effects of bed aging at the field scale may be partly responsible for the increasing destructiveness of secondary flows of landslides and debris flows.

  11. [Structural analysis of the new model of primary care in the community of Valencia].

    Compañ, L; Portella, E; Peiró, S


    To analyse the structure of the new model of primary care (NMPC) in the Community of Valencia, and to identify the strategic importance of its characteristic variables and the possibilities of intervention to affect these variables. A qualitative study through a method of structural analysis (crossed impact method-multiplication applied to a classification) of the relationships between 37 variables characterising the NMPC which were identified by prior qualitative research, with interpretation of the results using the Téniere-Buchot Model. Community of Valencia. The structural variables identified were those relating to the political-legal framework and to the allocation of primary care resources; and the resultant variables, those relating to efficiency and primary care quality. Between these two categories, the intervention variables covered management, NMPC professionals, health needs and the community's use of services. The structural analysis gives the legal-political and economical framework a determining role in NMPC, which can hardly be influenced from within the system. Management and organisation are identified as key variables from which an intervention can be made in the short or medium term to achieve the aims of the system.

  12. Generation, culture and flow-cytometric characterization of primary mouse macrophages.

    Schleicher, Ulrike; Bogdan, Christian


    Macrophages are not only host cells for many pathogens, but also fulfill several key functions in the innate and adaptive immune response, including the release of pro- and anti-inflammatory cytokines, the generation of organic and inorganic autacoids, the phagocytosis and killing of intracellular microorganisms or tumor cells, and the degradation and presentation of antigens. Several of these functions are shared by other immune cells, including dendritic cells, granulocytes, NK cells, and/or T lymphocytes. Thus, the analysis of macrophage functions in vitro using primary mouse cell populations requires standardized methods for the generation and culture of macrophages that guarantee high cell purity as well as the absence of stimulatory microbial contaminants. This chapter presents methodology to achieve these aims.

  13. Effects of structural parameters and rigidity of driving diaphragm on flow characteristics of micro valveless pump

    谢海波; 傅新; 杨华勇


    The structure and operating principle of micro valveless pump were investigated theoretically and experimentally. The mathematical model of pressure and flow rate within the micro nozzle/diffuser was established to analyze the effects of nozzle/diffuser parameters on the output flow rate of the micro valveless pump.The experiments were carried out with different structural parameters, driving frequencies, vibration amplitudes and stiffness of the driving diaphragms. Effects of the structural parameters and driving conditions on the operation performance of the pump are discussed in detail. The work provides useful reference for structure optimization selection of the driving diaphragm of micro valveless pump.

  14. Effects of structural parameters and rigidity of driving diaphragm on flow characteristics of micro valveless pump

    谢海波; 傅新; 杨华勇


    The structure and operating principle of micro valveless pump were investigated theoretically and experimentally. The mathematical model of pressure and flow rate within the micro nozzle/diffuser was established to analyze the effects of nozzle/diffuser parameters on the output flow rate of the micro valveless pump. The experiments were carried out with different structural parameters, driving frequencies, vibration amplitudes and stiffness of the driving diaphragms. Effects of the structural parameters and driving conditions on the operation performance of the pump are discussed in detail. The work provides useful reference for structure optimization selection of the driving diaphragm of micro valveless pump.

  15. Effects of atomic grain boundary structures on primary radiation damage in α-Fe

    Esfandiarpour, A. [Department of Physics, Payame Noor University (PNU), P.O. BOX 19395-3697, Tehran (Iran, Islamic Republic of); Feghhi, S.A.H., E-mail: [Department of Radiation Application, Shahid Beheshti University G.C., Tehran (Iran, Islamic Republic of); Shokri, A.A. [Department of Physics, Payame Noor University (PNU), P.O. BOX 19395-3697, Tehran (Iran, Islamic Republic of)


    In this paper, we used five different grain boundary (GB) structures including two twists, two symmetric tilts and one asymmetric tilt for α-Fe, in order to study the influence of different GB structures on the production and time evolution of defects. Energetic behavior of point defects near GBs is investigated and analyzed using Molecular Static (MS) method to calculate and compare the “defect absorbency” of each structure. The primary radiation damage state near each GB structure is simulated using Molecular Dynamic (MD) method for 3 keV and 6 keV primary-knocked on atom (PKA) with velocity vector perpendicular to the GB plane at various distances in 300 K. We found that all five GB structures can decrease the defect number in bulk region, if cascade center locates on the GB plane (prefect overlap) and increase the vacancy number, if the overlap is imperfect. This depends on the energy of PKA and its distance from GB plane. Also, the results proved that the magnitude of the observed variations depends on the atomic structure of GB. Furthermore, the GBs that have stronger “interstitial absorbency” produce an excess concentration of vacancies in the bulk region, while the edge of the cascades overlaps with GB plane. This is the result of bigger “interstitial absorbency” of GBs in comparison with vacancies.

  16. Analysis of flow structures in supersonic plane mixing layers using the POD method

    YANG Qin; FU Song


    The proper orthogonal decomposition (POD) method was applied to analyzing the database obtained from the direct numerical simulation (DNS) of supersonic plane mixing layers. The effect of different forms of the inner products in the POD method was investigated. It was observed that the mean flow contributes to a predominant part of the total flow energy, and the energy spectrum of the turbulence fluctuations covers a wide range of POD modes. The patterns of leading (high energy) POD modes reveal that the flow structures exhibit spanwise counter rotating rolls, as well as oblique vortices. These flow patterns are insensitive to the velocity of the observer. As the convective Mach number increases, the energy spectrum be-comes wider, the leading POD modes contain more complicated structures, and the flow becomes more chaotic.

  17. Analysis of flow structures in supersonic plane mixing layers using the POD method


    The proper orthogonal decomposition(POD) method was applied to analyzing the database obtained from the direct numerical simulation(DNS) of supersonic plane mixing layers.The effect of different forms of the inner products in the POD method was investigated.It was observed that the mean flow contributes to a predominant part of the total flow energy,and the energy spectrum of the turbulence fluctuations covers a wide range of POD modes.The patterns of leading(high energy) POD modes reveal that the flow structures exhibit spanwise counter rotating rolls,as well as oblique vortices.These flow patterns are insensitive to the velocity of the observer.As the convective Mach number increases,the energy spectrum be-comes wider,the leading POD modes contain more complicated structures,and the flow becomes more chaotic.

  18. Analysis of dynamical flow structure in a square arrayed rod bundle

    Ikeno, Tsutomu, E-mail: [Nuclear Fuel Industries, Ltd., 950, Asashiro Nishi 1-Chome, Kumatori-Cho, Sennan-Gun, Osaka 590-0481 (Japan); Kajishima, Takeo, E-mail: [Department of Mechanical Engineering, Osaka University (Japan)


    Large eddy simulation (LES) of turbulent flow in a bare rod bundle was performed, and a new concept about the flow structure that enhances heat transport between subchannels was proposed. To investigate the geometrical effect, the LES was performed for three different values of rod diameter over pitch ratio (D/P = 0.7, 0.8, 0.9). The computational domain containing 4 subchannels was large enough to capture large-scale structures wide across subchannels. Lateral flow obtained was unconfined in a subchannel, and some flows indicated a pulsation through the rod gap between subchannels. The gap flow became strong as D/P increased, as existing experimental studies had reported. Turbulence intensity profile in the rod gap suggested that the pulsation was caused by the turbulence energy transferred from the main flow to the wall-tangential direction. This implied that the flow pulsation was an unsteady mode of the secondary flow and arose from the same geometrical effect of turbulence. This implication was supported by the analysis results: two-points correlation functions of fluctuating velocities indicated two length-scales, P-D and D, respectively of cross-sectional and longitudinal motions; turbulence stress in the cross-sectional mean flow contained a non-potential component, which represented energy injection through the unsteady longitudinal fluid motion.

  19. Structural elucidation of the mechanistic basis of degeneracy in the primary humoral response.

    Khan, Tarique; Salunke, Dinakar M


    The mechanistic basis for efficient combating of the infinite range of foreign Ags by the limited repertoire of naive Abs expressed on primary B cell surfaces during their first encounter was addressed through elegantly designed crystallographic analyses. Resolution of the discrepancy arising from the limited number of possible germline Ab receptors on primary B cells for recognizing the unlimited pool of possible Ags has been attempted by invoking the degenerate recognition potential of the germline Abs. Structural analyses of germline mAb BBE6.12H3 in an Ag-free state, as well as bound to four different peptide Ags, established the correlation of its degenerate specificity with conformational versatility of the paratope. Six distinct paratope topologies observed for a single germline mAb provided a quantitative description of the primary Ag recognition repertoire at the tertiary structural level. Each of the four different peptide Ags was bound specifically to a distinct conformation of the paratope, which was also different from that of the Ag-free states of the same germline mAb. A minimal conserved motif in the pristine Ag-combining site essential for multispecificity and Ag binding-mediated change in the elbow angle of Fab was also discernible. It is proposed that the generation of a primary Ab repertoire involves large, yet finite, germline Ab clones, each capable of adopting discrete conformations, which in turn exhibit diverse binding modes.

  20. Investigation of structure of superconducting power transmission cables with LN2 counter-flow cooling

    Furuse, Mitsuho; Fuchino, Shuichiro; Higuchi, Noboru


    Establishment of long-distance cooling techniques and design of a compact cross section are required for development of HTC superconducting underground power cables. To save space of return coolant, a counter-flow cooling system appears promising. However, it is difficult to cool down long cables because of heat exchange between counter-flows due to high thermal conductivity of dielectric materials which separate both flows in range of liquid nitrogen temperature. We estimated temperature distributions analytically along model HTS power cables with counter-flow. Results of calculation showed that when liquid-nitrogen-impregnated polypropylene laminated paper was chosen for a dielectric material, great thickness was required to reduce heat exchange between counter-flows. We investigated various cable structures to optimize the counter-flow cooling system and cable size.

  1. Structural optimization of porous media for fast and controlled capillary flows.

    Shou, Dahua; Fan, Jintu


    A general quantitative model of capillary flow in homogeneous porous media with varying cross-sectional sizes is presented. We optimize the porous structure for the minimization of the penetration time under global constraints. Programmable capillary flows with constant volumetric flow rate and linear evolution of flow distance to time are also obtained. The controlled innovative flow behaviors are derived based on a dynamic competition between capillary force and viscous resistance. A comparison of dynamic transport on the basis of the present design with Washburn's equation is presented. The regulation and maximization of flow velocity in porous materials is significant for a variety of applications including biomedical diagnostics, oil recovery, microfluidic transport, and water management of fabrics.


    Chi-Xing Zhou


    Conceptually, an imagined conformation ellipsoid is supposed to represent the shape of a polymer chain for polymer melts in flow fields and to be equivalent to the volume element in a mathematical sense in continuum mechanics. A power law dependence of shear modulus of polymer melts on detC, referred to as envelope volume, is proposed. Based on those assumptions and the non-linear relation of shear modulus, a phenomenological viscoelastic model is derived. The model is tested in simple shear flow, simple elongational flow, oscillatory shear flow, and relaxation process after flow suddenly stopped. The results show that the model works well to predict the change of internal structure and viscoelastic performance of polymer melts in flow fields.

  3. Efficient blood flow visualization using flowline extraction and opacity modulation based on vascular structure analysis.

    Kwon, Ohjae; Lee, Jeongjin; Kim, Bohyoung; Shin, Juneseuk; Shin, Yeong-Gil


    With the recent advances regarding the acquisition and simulation of blood flow data, blood flow visualization has been widely used in medical imaging for the diagnosis and treatment of pathological vessels. In this paper, we present a novel method for the visualization of the blood flow in vascular structures. The vessel inlet or outlet is first identified using the orthogonality metric between the normal vectors of the flow velocity and vessel surface. Then, seed points are generated on the identified inlet or outlet by Poisson disk sampling. Therefore, it is possible to achieve the automatic seeding that leads to a consistent and faster flow depiction by skipping the manual location of a seeding plane for the initiation of the line integration. In addition, the early terminated line integration in the thin curved vessels is resolved through the adaptive application of the tracing direction that is based on the flow direction at each seed point. Based on the observation that blood flow usually follows the vessel track, the representative flowline for each branch is defined by the vessel centerline. Then, the flowlines are rendered through an opacity assignment according to the similarity between their shape and the vessel centerline. Therefore, the flowlines that are similar to the vessel centerline are shown transparently, while the different ones are shown opaquely. Accordingly, the opacity modulation method enables the flowlines with an unusual flow pattern to appear more noticeable, while the visual clutter and line occlusion are minimized. Finally, Hue-Saturation-Value color coding is employed for the simultaneous exhibition of flow attributes such as local speed and residence time. The experiment results show that the proposed technique is suitable for the depiction of the blood flow in vascular structures. The proposed approach is applicable to many kinds of tubular structures with embedded flow information.

  4. Complex Dynamic Flows in Solar Flare Sheet Structures

    McKenzie, David E.; Reeves, Katharine K.; Savage, Sabrina


    Observations of high-energy emission from solar flares often reveal the presence of large sheet-like structures, sometimes extending over a space comparable to the Sun's radius. Given that these structures are found between a departing coronal mass ejection and the post-eruption flare arcade, it is natural to associate the structure with a current sheet; though the relationship is unclear. Moreover, recent high-resolution observations have begun to reveal that the motions in this region are highly complex, including reconnection outflows, oscillations, and apparent wakes and eddies. We present a detailed first look at the complicated dynamics within this supra-arcade plasma, and consider implications for the interrelationship between the plasma and its embedded magnetic field.

  5. Flow and permeability structure of the Beowawe, Nevada hydrothermal system

    Faulder, D.D. [Lockheed Idaho Technologies Co., Idaho Falls, ID (United States); Johnson, S.D.; Benoit, W.R. [Oxbow Power Services, Inc., Reno, NV (United States)


    A review of past geologic, geochemical, hydrological, pressure transient, and reservoir engineering studies of Beowawe suggests a different picture of the reservoir than previously presented. The Beowawe hydrothermal contains buoyant thermal fluid dynamically balanced with overlying cold water, as shown by repeated temperature surveys and well test results. Thermal fluid upwells from the west of the currently developed reservoir at the intersection of the Malpais Fault and an older structural feature associated with mid-Miocene rifting. A tongue of thermal fluid rises to the east up the high permeability Malpais Fault, discharges at the Geysers area, and is in intimate contact with overlying cooler water. The permeability structure is closely related to the structural setting, with the permeability of the shallow hydrothermal system ranging from 500 to 1,000 D-ft, while the deeper system ranges from 200 to 400 D-ft.

  6. Stop Flow Lithography Synthesis and Characterization of Structured Microparticles

    David Baah


    Full Text Available In this study, the synthesis of nonspherical composite particles of poly(ethylene glycol diacrylate (PEG-DA/SiO2 and PEG-DA/Al2O3 with single or multiple vias and the corresponding inorganic particles of SiO2 and Al2O3 synthesized using the Stop Flow Lithography (SFL method is reported. Precursor suspensions of PEG-DA, 2-hydroxy-2-methylpropiophenone, and SiO2 or Al2O3 nanoparticles were prepared. The precursor suspension flows through a microfluidic device mounted on an upright microscope and is polymerized in an automated process. A patterned photomask with transparent geometric features masks UV light to synthesize the particles. Composite particles with vias were synthesized and corresponding inorganic SiO2 and Al2O3 particles were obtained through polymer burn-off and sintering of the composites. The synthesis of porous inorganic particles of SiO2 and Al2O3 with vias and overall dimensions in the range of ~35–90 µm was achieved. BET specific surface area measurements for single via inorganic particles were 56–69 m2/g for SiO2 particles and 73–81 m2/g for Al2O3 particles. Surface areas as high as 114 m2/g were measured for multivia cubic SiO2 particles. The findings suggest that, with optimization, the particles should have applications in areas where high surface area is important such as catalysis and sieving.

  7. Modeling turbulence structure. Chemical kinetics interaction in turbulent reactive flows

    Magnussen, B.F. [The Norwegian Univ. of Science and Technology, Trondheim (Norway)


    The challenge of the mathematical modelling is to transfer basic physical knowledge into a mathematical formulation such that this knowledge can be utilized in computational simulation of practical problems. The combustion phenomena can be subdivided into a large set of interconnected phenomena like flow, turbulence, thermodynamics, chemical kinetics, radiation, extinction, ignition etc. Combustion in one application differs from combustion in another area by the relative importance of the various phenomena. The difference in fuel, geometry and operational conditions often causes the differences. The computer offers the opportunity to treat the individual phenomena and their interactions by models with wide operational domains. The relative magnitude of the various phenomena therefore becomes the consequence of operational conditions and geometry and need not to be specified on the basis of experience for the given problem. In mathematical modelling of turbulent combustion, one of the big challenges is how to treat the interaction between the chemical reactions and the fluid flow i.e. the turbulence. Different scientists adhere to different concepts like the laminar flamelet approach, the pdf approach of the Eddy Dissipation Concept. Each of these approaches offers different opportunities and problems. All these models are based on a sound physical basis, however none of these have general validity in taking into consideration all detail of the physical chemical interaction. The merits of the models can only be judged by their ability to reproduce physical reality and consequences of operational and geometric conditions in a combustion system. The presentation demonstrates and discusses the development of a coherent combustion technology for energy conversion and safety based on the Eddy Dissipation Concept by Magnussen. (author) 30 refs.

  8. Flow sorting and exome sequencing reveal the oncogenome of primary Hodgkin and Reed-Sternberg cells.

    Reichel, Jonathan; Chadburn, Amy; Rubinstein, Paul G; Giulino-Roth, Lisa; Tam, Wayne; Liu, Yifang; Gaiolla, Rafael; Eng, Kenneth; Brody, Joshua; Inghirami, Giorgio; Carlo-Stella, Carmelo; Santoro, Armando; Rahal, Daoud; Totonchy, Jennifer; Elemento, Olivier; Cesarman, Ethel; Roshal, Mikhail


    Classical Hodgkin lymphoma (cHL) is characterized by sparsely distributed Hodgkin and Reed-Sternberg (HRS) cells amid reactive host background, complicating the acquisition of neoplastic DNA without extensive background contamination. We overcame this limitation by using flow-sorted HRS and intratumor T cells and optimized low-input exome sequencing of 10 patient samples to reveal alterations in genes involved in antigen presentation, chromosome integrity, transcriptional regulation, and ubiquitination. β-2-microglobulin (B2M) is the most commonly altered gene in HRS cells, with 7 of 10 cases having inactivating mutations that lead to loss of major histocompatibility complex class I (MHC-I) expression. Enforced wild-type B2M expression in a cHL cell line restored MHC-I expression. In an extended cohort of 145 patients, the absence of B2M protein in the HRS cells was associated with lower stage of disease, younger age at diagnosis, and better overall and progression-free survival. B2M-deficient cases encompassed most of the nodular sclerosis subtype cases and only a minority of mixed cellularity cases, suggesting that B2M deficiency determines the tumor microenvironment and may define a major subset of cHL that has more uniform clinical and morphologic features. In addition, we report previously unknown genetic alterations that may render selected patients sensitive to specific targeted therapies. © 2015 by The American Society of Hematology.

  9. Purification and Primary Structure Determination of a Novel Polypeptide Isolated from Mistletoe Viscum coloratum

    Jing Lin KONG; Xiu Bao DU; Chong Xu FAN; Ying CAO; Hui JIANG; Jian Fu XU; Xiao Jun ZHENG


    A novel polypeptide was isolated from mistletoe Viscum coloratum. The primary structure of the polypeptide 'named viscotoxin B2' was determined to be KSCCKNTTGRNIYNT CRFAGGSRERCAKLSGCKIISASTCPSDYPK by Edman degradation. Viscotoxin B2 shared high sequence homology with viscotoxins isolated from Viscum album. Pharmacological experiments showed that viscotoxin B2 had distinct cytotoxic activity on tumor cells. Viscotoxin B2 could be used as a leading compound in cancer therapy.

  10. Validation of computational fluid dynamics calculation using Rossendorf coolant mixing model flow measurements in primary loop of coolant in a pressurized water reactor model

    Farkas, Istvan; Hutli, Ezddin; Faekas, Tatiana; Takacs, Antal; Guba, Attila; Toth, Ivan [Dept. of Thermohydraulics, Centre for Energy Research, Hungarian Academy of Sciences, Budapest (Hungary)


    The aim of this work is to simulate the thermohydraulic consequences of a main steam line break and to compare the obtained results with Rossendorf Coolant Mixing Model (ROCOM) 1.1 experimental results. The objective is to utilize data from steady-state mixing experiments and computational fluid dynamics (CFD) calculations to determine the flow distribution and the effect of thermal mixing phenomena in the primary loops for the improvement of normal operation conditions and structural integrity assessment of pressurized water reactors. The numerical model of ROCOM was developed using the FLUENT code. The positions of the inlet and outlet boundary conditions and the distribution of detailed velocity/turbulence parameters were determined by preliminary calculations. The temperature fields of transient calculation were averaged in time and compared with time-averaged experimental data. The perforated barrel under the core inlet homogenizes the flow, and therefore, a uniform temperature distribution is formed in the pressure vessel bottom. The calculated and measured values of lowest temperature were equal. The inlet temperature is an essential parameter for safety assessment. The calculation predicts precisely the experimental results at the core inlet central region. CFD results showed a good agreement (both qualitatively and quantitatively) with experimental results.

  11. Modelling material effects on flow-accelerated corrosion in primary CANDU coolant and secondary reactor feed-water

    Phromwong, P.; Lister, D., E-mail: [Univ. of New Brunswick, Dept. of Chemical Engineering, Fredericton, New Brunswick (Canada); Uchida, S. [Japan Atomic Energy Agency, Tokai-mura, Ibaraki (Japan)


    The effects of chromium content on flow-accelerated corrosion (FAC) of carbon steel have been predicted very well by including a passivating layer, which is a chromium-dependent diffusion barrier at the metal-oxide interface. By adjusting the properties of the chromium-dependent layer, described with a Passivation Parameter (PP), we can predict the FAC of carbon steel of different chromium contents in typical reactor feed-water environments (140{sup o}C and neutral or ammoniated chemistry). The model and an appropriate PP are also applied to the environment typical of carbon-steel feeders in the primary coolant of a CANDU reactor (310{sup o}C and lithiated chemistry). The model predicts FAC rate very well (with a deviation of 10% or less) in both situations. (author)

  12. Numerical investigation on the flow structures in a narrow confined channel with staggered jet array arrangement

    Liu Haiyong


    Full Text Available A series of numerical analyses have been performed to investigate the flow structures in a narrow confined channel with 12 staggered circular impingement holes and one bigger exit hole. The flow enters the channel through the impingement holes and exits through the far end outlet. The flow fields corresponding to two jet Reynolds numbers (25000 and 65000 and three channel configurations with different ratios of the channel height to the impingement hole diameter (Zr = 1, 3, 5 are analyzed by solving the Reynolds averaged Navier–Stokes equations with the realizable k–ε turbulence model. Detailed flow field information including the secondary flow, the interaction between the jets and the cross flow, and flow distribution along the channel has been obtained. Comparisons between the numerical and experimental results of the flow fields at the four planes along the channel are performed to validate the numerical method. The calculated impingement pattern, high velocity flow distribution, low velocity separation region and vortices are in good agreement with the experimental data, implying the validity and effectiveness of the employed numerical approach for analyzing relevant flow field.

  13. Flow-induced structuring of dense protein dispersions

    Manski, J.M.


    Both health and sustainability are drivers for the increased interest in the creation of novel foods comprising a high protein content. The key challenge is the formation of an attractive, stable and palatable food texture, which is mainly determined by the food structure. In this research, new proc

  14. Flow-structure-seabed interactions in coastal and marine environments

    Sumer, B. Mutlu


    related to structures such as marine pipelines, offshore windfarms, and multiuse offshore platforms. Tsunamis, which received considerable attention after two recent extreme events (2004 Indonesia tsunami and 2011 Japan tsunami) are also included in the discussion. Marine hydro-geomechanics is highlighted...

  15. Self-Efficacy, School Resources, Job Stressors and Burnout among Spanish Primary and Secondary School Teachers: A Structural Equation Approach

    Betoret, Fernando Domenech


    This study examines the relationship between school resources, teacher self-efficacy, potential multi-level stressors and teacher burnout using structural equation modelling. The causal structure for primary and secondary school teachers was also examined. The sample was composed of 724 primary and secondary Spanish school teachers. The changes…

  16. NMR strategies to support medicinal chemistry workflows for primary structure determination.

    Oguadinma, Paul; Bilodeau, Francois; LaPlante, Steven R


    Central to drug discovery is the correct characterization of the primary structures of compounds. In general, medicinal chemists make great synthetic and characterization efforts to deliver the intended compounds. However, there are occasions which incorrect compounds are presented, such as those reported for Bosutinib and TIC10. This may be due to a variety of reasons such as uncontrolled reaction schemes, reliance on limited characterization techniques (LC-MS and/or 1D 1H NMR spectra), or even the lack of availability or knowledge of characterization strategies. Here, we present practical NMR approaches that support medicinal chemist workflows for addressing compound characterization issues and allow for reliable primary structure determinations. These strategies serve to differentiate between regioisomers and geometric isomers, distinguish between N- versus O-alkyl analogues, and identify rotamers and atropisomers. Overall, awareness and application of these available NMR methods (e.g. HMBC/HSQC, ROESY and VT experiments, to name only a few) should help practicing chemists to reveal chemical phenomena and avoid mis-assignment of the primary structures of compounds. Copyright © 2016 Elsevier Ltd. All rights reserved.

  17. Team structure, team climate and the quality of care in primary care: an observational study.

    Bower, P; Campbell, S; Bojke, C; Sibbald, B


    To determine whether practice structure (for example, list size, number of staff) predicts team processes and whether practice structure and team process in turn predict team outcomes Observational study using postal questionnaires and medical note audit. Team process was assessed through a measure of "climate" which examines shared perceptions of organisational policies, practices, and procedures. Primary care. Members of the primary health care team from 42 practices. Objective measures of quality of chronic disease management, patients' evaluations of practices, teams' self-reported ratings of effectiveness, and innovation. Team climate was better in singlehanded practices than in partnerships. Practices with longer booking intervals provided superior chronic disease management. Higher team climate scores were associated with superior clinical care in diabetes, more positive patient evaluations of practice and self-reported innovation and effectiveness. Although the conclusions are preliminary because of the limited sample size, the study suggests that there are important relationships between team structure, process, and outcome that may be of relevance to quality improvement initiatives in primary care. Possible causal mechanisms that might underlie these associations remain to be determined.

  18. Long Wave Flow Interaction with a Single Square Structure on a Sloping Beach

    Gian C. Bremm


    Full Text Available In the context of dam breaks, tsunami, and flash floods, it is paramount to quantify the time-history of forces by the rapidly transient flow to vertical structures and the characteristics of the induced flow patterns. To resemble on-land tsunami-induced flow, a free-surface-piercing structure is exposed to long leading depression waves in a tsunami flume where long waves run up and down a 1:40 smooth and impermeable sloping beach after its generation by a volume-driven wave maker. The structure and its surrounding were monitored with force transducers, pressure gauges and cameras. Preparatory steady-state experiments were accomplished to determine the drag force coefficient of the square cylinder at various water depths. The flow during wave run-up and draw-down acting on the structure resulted in distinct flow pattern which were characteristic for the type of flow-structure interaction. Besides bow wave propagating upstream, a standing or partially-standing wave was observed in front of the structure together with a wake formation downstream, while a von Kármán vortex street developed during the deceleration phase of the flow motion and during draw-down. Force measurements indicated a sudden increase in the stream-wise total force starting with the arrival of the flow front during initial run-up. Lateral velocities showed significant oscillations in correlation with the von Kármán vortex street development. A comparison of the total measured base force with the analytically-calculated share of the drag force revealed that forces were prevailingly drag-dominated.

  19. Imbalance between Goals and Organizational Structure in Primary Health Care in Iran- a Systematic Review.

    Zanganeh Baygi, Mehdi; Seyedin, Hesam


    In recent years, the main focus of health sector reforms in Iran is the family physician and referral system plan. Fundamental changes in the goals and strategies, has increased the necessity of the need to reform the organizational structure. This study tries to review and summarize all cases about the organizational structure of Iran and its challenges in primary health care system. This study was a systematic review of published and grey literature. We searched the relevant databases, bibliography of related papers, and laws, using appropriate search strategies and key words. The CASP tool was used by two experts to evaluate the quality of retrieved papers and inconsistencies were resolved by discussion. After removal of duplicate citations, a total of 52 titles were identified through database searching, among which 30 met the inclusion criteria. Considering the research quality criteria, 14 papers were recognized qualified, which were categorized into two groups of: articles and policies. The results showed ineffectiveness of the current organizational structure at different level. The majority of the papers recommend performing reforms in the system because of changes in goals and strategies. Also, some suggest an appropriate information system to be designed in the current structures. Centralization and delegation process are the main discussions for the studies. Because of fundamental changes in goals and strategies, reforms in the organizational structure of primary health system in Iran especially in peripheral levels are highly recommended.

  20. Imbalance between Goals and Organizational Structure in Primary Health Care in Iran- a Systematic Review

    Mehdi Zanganeh Baygi


    Full Text Available Background: In recent years, the main focus of health sector reforms in Iran is the family physician and referral system plan. Fundamental changes in the goals and strategies, has increased the necessity of the need to reform the organizational structure. This study tries to review and summarize all cases about the organizational structure of Iran and its challenges in primary health care system.Methods: This study was a systematic review of published and grey literature. We searched the relevant databases, bibliography of related papers, and laws, using appropriate search strategies and key words. The CASP tool was used by two experts to evaluate the quality of retrieved papers and inconsistencies were resolved by discussion.Results: After removal of duplicate citations, a total of 52 titles were identified through database searching, among which 30 met the inclusion criteria. Considering the research quality criteria, 14 papers were recognized qualified, which were categorized into two groups of: articles and policies. The results showed ineffectiveness of the current organizational structure at different level. The majority of the papers recommend performing reforms in the system because of changes in goals and strategies. Also, some suggest an appropriate information system to be designed in the current structures. Centralization and delegation process are the main discussions for the studies.Conclusion: Because of fundamental changes in goals and strategies, reforms in the organizational structure of primary health system in Iran especially in peripheral levels are highly recommended.

  1. Asphalts and asphaltenes: Macromolecular structure, precipitation properties, and flow in porous media

    Rassamdana, Hossein

    Depending on rock and fluid properties, more than 50% of reservoir oil in place is normally produced by enhanced oil recovery (EOR) methods. Among the EOR techniques, miscible flooding is one of the most efficient and widely-used methods. However, this method can suffer from the formation and precipitation of asphalt aggregates. In addition, asphalt deposition is also a major hindrance to heavy oil production, and even primary recovery operations. Asphalt deposition can alter the reservoir rock properties, fluid saturation distribution, fluid flow properties, and eventually the ultimate oil recovery. The shortage of studies on the macromolecular structure and growth mechanisms of asphalt particles is the main reason for the unsuccessful modeling of their precipitation properties. The equivocal behavior of asphalt under some specific conditions could be the other reason. In this research we look at the problem of asphalt formation, flow, and precipitation from three different angles. We analyze extensive small-angle X-ray and neutron scattering data, precipitation data, and molecular weight distribution measurements, and show that they all suggest conclusively that asphalts and asphaltenes are fractal aggregates, and their growth mechanisms are diffusion-limited particle (DLP) and diffusion-limited cluster-cluster (DLCC) aggregation processes. These results lead us to development of a scaling equation of state for predicting asphalt precipitation properties, such as its onset and amount of precipitation. Another result of our study is an analytical equation for modeling the molecular weight distribution of asphalt and asphaltene aggregates. In addition, asphalt phase behavior in miscible and immiscible injections is studied. The effect of the governing thermodynamic factors, such as the pressure, temperature, and composition of the oil and precipitation agents, on the asphalt aggregation and disaggregation processes are investigated. Finally, a model is developed to

  2. Analysis of Flow Structure and Calculation of Drag Coefficient for Concurrent-up Gas-Solid Flow

    杨宁; 王维; 等


    This study investigates the heterogeneous structure and its influence on drag coefficient for concurrent up gas-solid flow.The energy-minimization multi-scale (EMMS) model is modified to simulate the variation of structure parameters with solids concentration,showing the tendency for particles to aggregated to form clusters and for fluid to pass around clusters.The global drag coefficient is resolved into that for the dense phase,for the dilutephase and for the so-called inter-phase,all of which can be obtained from their respective phase-specific structure parameters.The computational results show that the drag coefficients of the different phases are quite different,and the global drag coefficient calculated from the EMMS approach is much lower than that from the correlation of Wen and Yu.The simulation results demonstrate that the EMMS approach can well describe the heterogeneous flow structure,and is very promising for incorporation into the two-fluid model or the discrete particle model as the closure law for drag coefficient.

  3. Coronary flow of the infarct artery assessed by transthoracic Doppler after primary percutaneous coronary intervention predicts final infarct size.

    Trifunovic, Danijela; Sobic-Saranovic, Dragana; Beleslin, Branko; Stankovic, Sanja; Marinkovic, Jelena; Orlic, Dejan; Vujisic-Tesic, Bosiljka; Petrovic, Milan; Nedeljkovic, Ivana; Banovic, Marko; Djukanovic, Nina; Petrovic, Olga; Petrovic, Marija; Stepanovic, Jelena; Djordjevic-Dikic, Ana; Tesic, Milorad; Ostojic, Miodrag


    Coronary microcirculatory function after primary percutaneous coronary intervention (pPCI) in patients with acute myocardial infarction is important determinant of infarct size (IS). Our aim was to investigate the utility of coronary flow reserve (CFR) and diastolic deceleration time (DDT) of the infarct artery (IRA) assessed by transthoracic Doppler echocardiography after pPCI for final IS prediction. In 59 patients, on the 2nd day after pPCI for acute anterior myocardial infarction, transthoracic Doppler analysis of IRA blood flow was done including measurements of CFR, baseline DDT and DDT during adenosine infusion (DDT adeno). Killip class, myocardial blush grade, resolution of ST segment elevation, peak creatine kinase-myocardial band and conventional echocardiographic parameters were determined. Single-photon emission computed tomography myocardial perfusion imaging was done 6 weeks later to define final IS (percentage of myocardium with fixed perfusion abnormality). IS significantly correlated with CFR (r = -0.686, p 20 %), the best cut-off for CFR was <1.73 (sensitivity 65 %, specificity 96 %) and for DDT adeno ≤720 ms (sensitivity 81 %, specificity 96 %). CFR and DDT during adenosine are independent and powerful early predictors of final IS offering incremental prognostic information over conventional parameters of myocardial and microvascular damage and tissue reperfusion.

  4. Visualization of boiling flow structure in a natural circulation boiling loop

    Karmakar, Arnab; Paruya, Swapan, E-mail:


    Highlights: • Vapor–liquid jet flows in natural circulation boiling loop. • Flow patterns and their transitions during geysering instability in the loop. • Evaluation of the efficiency of the needle probe in detecting the vapor–liquid and boiling flow structure. - Abstract: The present study reports vapor–liquid jet flows, flow patterns and their transitions during geysering instability in a natural circulation boiling loop under varied inlet subcooling ΔT{sub sub} (30–50 °C) and heater power Q (4–5 kW). Video imaging, voltage measurement using impedance needle probe, measurement of local pressure and loop flow rate have been carried out in this study. Power spectra of the voltage, the pressure and the flow rate reveal that at a high ΔT{sub sub} the jet flows have long period (21.36–86.95 s) and they are very irregular with a number of harmonics. The period decreases and becomes regular with a decrease of ΔT{sub sub}. The periods of the jet flows at ΔT{sub sub} = 30–50 °C and Q = 4 kW are in close agreement with those obtained from the video imaging. The probe was found to be more efficient than the pressure sensor in detecting the jet flows within an uncertainty of 9.5% and in detecting a variety of bubble classes. Both the imaging and the probe consistently identify the bubbly flow/vapor-mushrooms transition or the bubbly flow/slug flow transition on decreasing ΔT{sub sub} or on increasing Q.

  5. Timing mirror structures observed by Cluster with a magnetosheath flow model

    V. Génot


    Full Text Available The evolution of structures associated with mirror modes during their flow in the Earth's magnetosheath is studied. The fact that the related magnetic fluctuations can take distinct shapes, from deep holes to high peaks, has been assessed in previous works on the observational, modeling and numerical points of view. In this paper we present an analytical model for the flow lines and velocity magnitude inside the magnetosheath. This model is used to interpret almost 10 years of Cluster observations of mirror structures: by back tracking each isolated observation to the shock, the "age", or flow time, of these structures is determined together with the geometry of the shock. Using this flow time the evolutionary path of the structures may be studied with respect to different quantities: the distance to mirror threshold, the amplitude of mirror fluctuations and the skewness of the magnetic amplitude distribution as a marker of the shape of the structures. These behaviours are confronted to numerical simulations which confirm the dynamical perspective gained from the association of the statistical analysis and the analytical model: magnetic peaks are mostly formed just behind the shock and are quickly overwhelmed by magnetic holes as the plasma conditions get more mirror stable. The amplitude of the fluctuations are found to saturate before the skewness vanishes, i.e. when both structures quantitatively balance each other, which typically occurs after a flow time of 100–200 s in the Earth's magnetosheath. Comparison with other astrophysical contexts is discussed.

  6. Re-examination of Large Scale Structure & Cosmic Flows

    Davis, Marc; Nusser, Adi


    Comparison of galaxy flows with those predicted from the local galaxy distribution ended as an active field after two analyses came to vastly different conclusions 25 years ago, but that was due to faulty data. All the old results are therefore suspect. With new data collected in the last several years, the problem deserves another look. The goal is to explain the 640 km/s dipole anisotropy of the CMBR. For this we analyze the gravity field inferred from the enormous data set derived from the 2MASS collection of galaxies (Huchra et al. 2005), and compare it to the velocity field derived from the well calibrated SFI++ Tully-Fisher catalog (Springob et al. 2007). Using the ``Inverse Method'' to minimize Malmquist biases, within 10,000 km/s the gravity field is seen to predict the velocity field (Davis et al. 2011) to remarkable consistency. This is a beautiful demonstration of linear perturbation theory and is fully consistent with standard values of the cosmological variables.

  7. Friction Stir Lap Welding: material flow, joint structure and strength

    Z.W. Chen


    Full Text Available Friction stir welding has been studied intensively in recent years due to its importance in industrial applications. The majority of these studies have been based on butt joint configuration and friction stir lap welding (FSLW has received considerably less attention. Joining with lap joint configuration is also widely used in automotive and aerospace industries and thus FSLW has increasingly been the focus of FS research effort recently. number of thermomechancal and metallurgical aspects of FSLW have been studied in our laboratory. In this paper, features of hooking formed during FSLW of Al-to-Al and Mg-to-Mg will first be quantified. Not only the size measured in the vertical direction but hook continuity and hooking direction have been found highly FS condition dependent. These features will be explained taking into account the effects of the two material flows which are speed dependent and alloy deformation behaviour dependent. Strength values of the welds will be presented and how strength is affected by hook features and by alloy dependent local deformation behaviours will be explained. In the last part of the paper, experimental results of FSLW of Al-to-steel will be presented to briefly explain how joint interface microstructures affect the fracturing process during mechanical testing and thus the strength. From the results, tool positioning as a mean for achieving maximum weld strength can be suggested.

  8. Flow-Structure-Acoustic Interaction Computational Modeling of Voice Production inside an Entire Airway

    Jiang, Weili; Zheng, Xudong; Xue, Qian


    Human voice quality is directly determined by the interplay of dynamic behavior of glottal flow, vibratory characteristics of VFs and acoustic characteristics of upper airway. These multiphysics constituents are tightly coupled together and precisely coordinate to produce understandable sound. Despite many years' research effort, the direct relationships among the detailed flow features, VF vibration and aeroacoustics still remains elusive. This study utilizes a first-principle based, flow-structure-acoustics interaction computational modeling approach to study the process of voice production inside an entire human airway. In the current approach, a sharp interface immersed boundary method based incompressible flow solver is utilized to model the glottal flow; A finite element based solid mechanics solver is utilized to model the vocal vibration; A high-order immersed boundary method based acoustics solver is utilized to directly compute sound. These three solvers are fully coupled to mimic the complex flow-structure-acoustic interaction during voice production. The geometry of airway is reconstructed based on the in-vivo MRI measurement reported by Story et al. (1995) and a three-layer continuum based vocal fold model is taken from Titze and Talkin (1979). Results from these simulations will be presented and further analyzed to get new insight into the complex flow-structure-acoustic interaction during voice production. This study is expected to improve the understanding of fundamental physical mechanism of voice production and to help to build direct cause-effect relationship between biomechanics and voice sound.

  9. A mechanistic model for predicting flow-assisted and general corrosion of carbon steel in reactor primary coolants

    Lister, D. [University of New Brunswick, Fredericton, NB (Canada). Dept. of Chemical Engineering; Lang, L.C. [Atomic Energy of Canada Ltd., Chalk River Lab., ON (Canada)


    Flow-assisted corrosion (FAC) of carbon steel in high-temperature lithiated water can be described with a model that invokes dissolution of the protective oxide film and erosion of oxide particles that are loosened as a result. General corrosion under coolant conditions where oxide is not dissolved is described as well. In the model, the electrochemistry of magnetite dissolution and precipitation and the effect of particle size on solubility move the dependence on film thickness of the diffusion processes (and therefore the corrosion rate) away from reciprocal. Particle erosion under dissolving conditions is treated stochastically and depends upon the fluid shear stress at the surface. The corrosion rate dependence on coolant flow under FAC conditions then becomes somewhat less than that arising purely from fluid shear (proportional to the velocity squared). Under non-dissolving conditions, particle erosion occurs infrequently and general corrosion is almost unaffected by flow For application to a CANDU primary circuit and its feeders, the model was bench-marked against the outlet feeder S08 removed from the Point Lepreau reactor, which furnished one value of film thickness and one of corrosion rate for a computed average coolant velocity. Several constants and parameters in the model had to be assumed or were optimised, since values for them were not available. These uncertainties are no doubt responsible for the rather high values of potential that evolved as steps in the computation. The model predicts film thickness development and corrosion rate for the whole range of coolant velocities in outlet feeders very well. In particular, the detailed modelling of FAC in the complex geometry of one outlet feeder (F11) is in good agreement with measurements. When the particle erosion computations are inserted in the balance equations for the circuit, realistic values of crud level are obtained. The model also predicts low corrosion rates and thick oxide films for inlet

  10. A numerical study of the three-dimensional structure of the Taylor-Couette flow in eccentric configuration with superimposed cross flow

    Scurtu, Nicoleta; Egbers, Christoph [Brandenburgische Technische Universitaet (BTU), Cottbus (Germany); Stuecke, Peter [Westsaechsische Hochschule (WHZ), Zwickau (Germany)], E-mail:


    The eccentric small gap Taylor-Couette system with rotating inner cylinder and fixed outer cylinder is investigated numerically. The main flow fields were examined and the transition region from the laminar Couette-flow to the Taylor-vortex-flow in different eccentric arrangements of the cylinders. The effect of the eccentricity on flow patterns was studied for different values of the eccentricity between 0 and 0.75 in relation to the mean gap. This flow was further disturbed by the superimposed cross flow entering into the gap through the feed hole with a cross flow rate of 0.1 of the circumferential flow rate. Hence, more complex three dimensional flow structures evolved in the cylinders' gap, especially in the vicinity of the feed hole.

  11. Three-dimensional structure of dominant instabilities in turbulent flow over smooth and rough boundaries

    Grass, A. J.; Stuart, R. J.; Mansour-Tehrani, M.


    The current status of knowledge regarding coherent vortical structures in turbulent boundary layers and their role in turbulence generation are reviewed. The investigations reported in the study concentrate attention on rough-wall flows prevailing in the geophysical environment and include an experiment determining the three-dimensional form of the turbulence structures linked to the ejection and inrush events observed over rough walls and an experiment concerned with measuring the actual spanwise scale of the near-wall structures for boundary conditions ranging from hydrodynamically smooth to fully rough. It is demonstrated that horseshoe vortical structures are present and play an important role in rough-wall flows and they increase in scale with increasing wall distance, while a dominant spanwise wavelength occurs in the instantaneous cross-flow distribution of streamwise velocity close to the rough wall.

  12. Impact melt rocks from the Ries structure, Germany: an origin as impact melt flows?

    Osinski, Gordon R.


    The production of impact melt rocks and glasses is a characteristic feature of hypervelocity impact events on Earth and other planetary bodies. This investigation represents the first detailed study of an unusual series of coherent impact melt rocks intermittently exposed around the periphery of the ~24-km diameter, ~14.5 Ma Ries impact structure, Germany. Optical and analytical scanning electron microscopy (SEM) reveals that the groundmass comprises sanidine, plagioclase, quartz and ilmenite (decreasing order of abundance) with the interstices filled by either fresh or devitrified glassy mesostasis. Primary crystallites display skeletal, dendritic and/or spherulitic textures indicating rapid crystallization from a melt. The mesostasis is characterized by extreme chemical heterogeneity (e.g., FeO and Al 2O 3 contents from ~1 to ~62-80 wt.%). This is likely due to a combination of crystal-liquid fractionation during rapid cooling and crystallization of an originally incompletely homogenized melt. Vapor phase crystallization of sanidine and cristobalite occurred in miarolitic cavities during late-stage cooling of the impact melts. The most likely protolith for the impact melt rocks are granitic rocks present in the crystalline basement target. The high volatile content of the mesostasis suggests that a large volatile component was retained from this protolith. Field observations together with analytical data and micro-textures indicate that the Ries impact melt rocks were molten at the time of, and after, deposition. Field relations with other impactites also suggest that these rocks were emplaced subsequent to the excavation stage of crater formation and that they are not, therefore, ballistic ejecta. Thus, it is proposed that the Ries impact melt rocks were emplaced as ground-hugging impact melt flows that emanated from different regions of the evolving transient cavity during the modification stage of crater formation. This is consistent with, and in fact

  13. Study on flow behavior and structure over chined fuselage at high angle of attack


    A study of leeward vortex structure over chined fuselage and the effects of micro tip perturbation on its vortex flow have been carried out in wind tunnel experiments at Reynolds numbers from 1.26×105 to 5.04×105 with PIV and pressure measurement techniques.Firstly,the experiment results have proved that micro tip perturbation has no effects on the vortex flow and its aerodynamic characteristics over chined fuselage at high angle of attack,in which there are not any non-deterministic flow behaviors.Secondly,the evolution of leeward vortex structure over chined fuselage along the axis of model can be divided into four flow regimes:linear conical developed regime,decay regime of leeward vortex intensity,asymmetric leeward vortex break down regime and completely break down regime.And a correlation between leeward vortex structure and sectional aerodynamic force was also revealed in the present paper.Thirdly,the experiment results show the behavior of leeward vortex core trajectories and zonal characteristics of leeward vortex structure with angles of attack.Finally,the experiment results of Reynolds number effect on the leeward vortex flow have further confirmed research conclusions from previous studies:the flows over chined fuselage at high angles of attack are insensitive to variation of Reynolds number,and there is a little effect on the secondary boundary layer separation and the suction peak induced by leeward vortex.

  14. Using 3D CFD to reconcile different views of confluence flow structure

    Lane, S. N.


    River channel confluences have seen considerable attention in recent years. The aim of this presentation is to demonstrate how CFD has been used to evaluate and expand some of the results that have emerged from field and laboratory studies. Central to this research has been the use of three-dimensional numerical modelling techniques that are able to represent key hydrodynamic processes in confluences (e.g. water surface super-elevation, topographic forcing of flow, shear-driven turbulence), and to provide predictions of important explanatory variables (e.g. dynamic pressure). The research design is based upon using numerical simulation to explore interactions between amongst governing variables (e.g. tributary momentum ratio, degree of asymmetry, junction angle, tributary bed discordance). On the basis of more than 50 simulations of 'laboratory-style' confluences and a smaller number of field cases, this paper identifies the key controls upon confluence flow structures, and the potential influence of these structures upon geomorphological processes within the confluence. This demonstrates: (i) how divergence of opinion over confluence flow processes has resulted from different methods of instrument rotation in the field; (ii) the importance of both streamline curvature and flow separation as controls upon flow structure development; and (iii) the periodic nature of the flow structures that are seen in confluence environments, and which may be misunderstood when a series of time-averaged measurements are made in the field.

  15. Plasma depletion layer: Magnetosheath flow structure and forces

    Y. L. Wang


    Full Text Available The plasma depletion layer (PDL is a layer on the sunward side of the magnetopause with lower plasma density and higher magnetic field compared to the corresponding upstream magnetosheath values. In a previous study, we have validated the UCLA global (MHD model in studying the formation of the PDL by comparing model results, using spacecraft solar wind observations as the driver, with in situ PDL observations. In this study, we extend our previous work and examine the detailed MHD forces responsible for the PDL formation. We argue that MHD models, instead of gasdynamic models, should be used to study the PDL, because gasdynamic models cannot produce the PDL on the sunward side of the magnetopause. For northward (IMF, flux tube depletion occurs in almost all the subsolar magnetosheath. However, the streamlines closest to the magnetopause and the stagnation line show the greatest depletion. The relative strength of the various MHD forces changes along these streamlines. Forces along a flux tube at different stages of its depletion in the magnetosheath are analyzed. We find that a strong plasma pressure gradient force along the magnetic field at the bow shock and a pressure gradient force along the flux tube within the magnetosheath usually exist pushing plasma away from the equatorial plane to deplete the flux tube. More complex force structures along the flux tube are found close to the magnetopause. This new, more detailed description of flux tube depletion is compared with the results of Zwan and Wolf (1976 and differences are found. Near the magnetopause, the pressure gradient force along the flux tube either drives plasma away from the equatorial plane or pushes plasma toward the equatorial plane. As a result, a slow mode structure is seen along the flux tube which might be responsible for the observed two-layered slow mode structures.

    Key words. Magnetospheric physics (magnetosheath; solar wind-magnetosphere interactions. Space

  16. Effect of Levee and Channel Structures on Long Lava Flow Emplacement: Martian Examples from THEMIS and MOLA Data

    Peitersen, M. N.; Zimbelman, J. R.; Christensen, P. R.; Bare, C.


    Long lava flows (discrete flow units with lengths exceeding 50 km) are easily identified features found on many planetary surfaces. An ongoing investigation is being conducted into the origin of these flows. Here, we limit our attention to long lava flows which show evidence of channel-like structures.

  17. Complete primary structure of the major component myoglobin of California gray whale (Eschrichtius gibbosus).

    Bogardt, R A; Dwulet, F E; Lehman, L D; Jones, B N; Gurd, F R


    The complete primary structure of the major component myoglobin from the California gray whale, Eschrichtius gibbosus, was determined by specific cleavage of the protein to obtain large peptides for degradation by the automatic sequenator. Cleavage at the two methionine residues of the apomyoglobin with cyanogen bromide and at the three arginine residues of the methyl acetimidated protein with trypsin resulted in three and four easily separable peptides, respectively, which when sequenced accounted for 85% of the primary structure. The remainder of the covalent structure was obtained by further digestion of the central cyanogen bromide peptide with trypsin and S. aureus strain V8 protease. This protein differs from that of the sperm whale, Physeter catodon, at 12 positions, from that of the common porpoise, Phocoena phocoena, and the Black Sea dolphin, Delphinus delphis, at 14 positions, and from that of the Amazon River dolphin, Inia geoffrensis, at 7 positions. All substitutions observed in this sequence fit easily into the tertiary structure of sperm whale myoglobin.

  18. Debris flow impact on mitigation barriers: a new method for particle-fluid-structure interactions

    Marchelli, Maddalena; Pirulli, Marina; Pudasaini, Shiva P.


    Channelized debris-flows are a type of mass movements that involve water-charged, predominantly coarse-grained inorganic and organic material flowing rapidly down steep confined pre-existing channels (Van Dine, 1985). Due to their rapid movements and destructive power, structural mitigation measures have become an integral part of counter measures against these phenomena, to mitigate and prevent damages resulting from debris-flow impact on urbanized areas. In particular, debris barriers and storage basins, with some form of debris-straining structures incorporated into the barrier constructed across the path of a debris-flow, have a dual role to play: (1) to stimulate deposition by presenting a physical obstruction against flow, and (2) to guarantee that during normal conditions stream water and bedload can pass through the structure; while, during and after an extreme event, the water that is in the flow and some of the fine-grained sediment can escape. A new method to investigate the dynamic interactions between the flowing mass and the debris barrier is presented, with particular emphasis on the effect of the barrier in controlling the water and sediment content of the escaping mass. This aspect is achieved by implementing a new mechanical model into an enhanced two-phase dynamical mass flow model (Pudasaini, 2012), in which solid particles mixture and viscous fluid are taken into account. The complex mechanical model is defined as a function of the energy lost during impact, the physical and geometrical properties of the debris barrier, separate but strongly interacting dynamics of boulder and fluid flows during the impact, particle concentration distribution, and the slope characteristics. The particle-filtering-process results in a large variation in the rheological properties of the fluid-dominated escaping mass, including the substantial reduction in the bulk density, and the inertial forces of the debris-flows. Consequently, the destructive power and run

  19. Formation mechanism of primary phases and eutectic structures within undercooled Pb-Sb-Sn ternary alloys


    The solidification characteristics of three types of Pb-Sb-Sn ternary alloys with different primary phases were studied under substantial undercooling conditions. The experimental results show that primary (Pb) and SbSn phases grow in the dendritic mode, whereas primary (Sb) phase exhibits faceted growth in the form of polygonal blocks and long strips. (Pb) solid solution phase displays strong affinity with SbSn intermetallic compound so that they produce various morphologies of pseudobinary eutectics, but it can only grow in the divorced eutectic mode together with (Sb) phase. Although (Sb) solid solution phase and SbSn intermetallic com- pound may grow cooperatively within ternary eutectic microstructures, they sel- dom form pseudobinary eutectics independently. The (Pb)+(Sb)+SbSn ternary eutectic structure usually shows lamellar morphology, but appears as anomalous eutectic when its volume fraction becomes small. EDS analyses reveal that all of the three primary (Pb), (Sb) and SbSn phases exhibit conspicuous solute trapping effect during rapid solidification, which results in the remarkable extension of sol- ute solubility.

  20. Formation mechanism of primary phases and eutectic structures within undercooled Pb-Sb-Sn ternary alloys

    WANG WeiLi; DAI FuPing; WEI BingBo


    The solidification characteristics of three types of Pb-Sb-Sn ternary alloys with different primary phases were studied under substantial undercooling conditions. The experimental results show that primary (Pb) and SbSn phases grow in the dendritic mode, whereas primary (Sb) phase exhibits faceted growth in the form of polygonal blocks and long strips. (Pb) solid solution phase displays strong affinity with SbSn intermetallic compound so that they produce various morphologies of pseudobinary eutectics, but it can only grow in the divorced eutectic mode together with (Sb) phase. Although (Sb) solid solution phase and SbSn intermetallic compound may grow cooperatively within ternary eutectic microstructures, they seldom form pseudobinary eutectics independently. The (Pb)+(Sb)+SbSn ternary eutectic structure usually shows lamellar morphology, but appears as anomalous eutectic when its volume fraction becomes small. EDS analyses reveal that all of the three primary (Pb), (Sb) and SbSn phases exhibit conspicuous solute trapping effect during rapid solidification, which results in the remarkable extension of solute solubility.

  1. Thermal analysis and cooling structure design of the primary collimator in CSNS/RCS

    Zou, Yi-Qing; Kang, Ling; Qu, Hua-Min; He, Zhe-Xi; Yu, Jie-Bing; 10.1088/1674-1137/37/5/057004


    The rapid cycling synchrotron (RCS) of the China Spallation Neutron Source (CSNS) is a high intensity proton ring with beam power of 100 kW. In order to control the residual activation to meet the requirements of hands-on maintenance, a two-stage collimation system has been designed for the RCS. The collimation system consists of one primary collimator made of thin metal to scatter the beam and four secondary collimators as absorbers. Thermal analysis is an important aspect in evaluating the reliability of the collimation system. The calculation of the temperature distribution and thermal stress of the primary collimator with different materials is carried out by using ANSYS code. In order to control the temperature rise and thermal stress of the primary collimator to a reasonable level, an air cooling structure is intended to be used. The mechanical design of the cooling structure is presented, and the cooling effciency with different chin numbers and wind velocity is also analyzed. Finally, the fatigue life...

  2. Flow structures in end-view plane of slender delta wing

    Sahin Besir


    Full Text Available Present investigation focuses on unsteady flow structures in end-view planes at the trailing edge of delta wing, X/C=1.0, where consequences of vortex bursting and stall phenomena vary according to angles of attack over the range of 25° ≤ α ≤ 35° and yaw angles, β over the range of 0° ≤ β ≤ 20°. Basic features of counter rotating vortices in end-view planes of delta win with 70° sweep angle, Λ are examined both qualitatively and quantitatively using Rhodamine dye and the PIV system. In the light of present experiments it is seen that with increasing yaw angle, β symmetrical flow structure is disrupted continuously. Dispersed wind-ward side leading edge vortices cover a large part of flow domain, on the other hand, lee-ward side leading edge vortices cover only a small portion of flow domain.

  3. Numerical investigation of flow structure and pressure pulsation in the Francis-99 turbine during startup

    Minakov, A.; Sentyabov, A.; Platonov, D.


    We performed numerical simulation of flow in a laboratory model of a Francis hydroturbine at startup regimes. Numerical technique for calculating of low frequency pressure pulsations in a water turbine is based on the use of DES (k-ω Shear Stress Transport) turbulence model and the approach of “frozen rotor”. The structure of the flow behind the runner of turbine was analysed. Shows the effect of flow structure on the frequency and intensity of non-stationary processes in the flow path. Two version of the inlet boundary conditions were considered. The first one corresponded measured time dependence of the discharge. Comparison of the calculation results with the experimental data shows the considerable delay of the discharge in this calculation. Second version corresponded linear approximation of time dependence of the discharge. This calculation shows good agreement with experimental results.

  4. Kinematic Morphology of Large-scale Structure: Evolution from Potential to Rotational Flow

    Wang, Xin; Aragon-Calvo, Miguel A; Neyrinck, Mark C; Eyink, Gregory L


    As an alternative way of describing the cosmological velocity field, we discuss the evolution of rotational invariants constructed from the velocity gradient tensor. Compared with the traditional divergence-vorticity decomposition, these invariants, defined as coefficients of characteristic equation of the velocity gradient tensor, enable a complete classification of all possible flow patterns in the dark-matter comoving frame, including both potential and vortical flows. Before shell-crossing, different categories of potential flow are highly associated with cosmic web structure, because of the coherent evolution of density and velocity. This correspondence is even preserved at some level when vorticity is generated after shell-crossing. The evolution from the potential to vortical flow can be traced continuously by these invariants. With the help of this tool, we show that the vorticity is generated in a particular way that is highly correlated with the large-scale structure. This includes a distinct spatia...

  5. Maps of sparse Markov chains efficiently reveal community structure in network flows with memory

    Persson, Christian; Edler, Daniel; Rosvall, Martin


    To better understand the flows of ideas or information through social and biological systems, researchers develop maps that reveal important patterns in network flows. In practice, network flow models have implied memoryless first-order Markov chains, but recently researchers have introduced higher-order Markov chain models with memory to capture patterns in multi-step pathways. Higher-order models are particularly important for effectively revealing actual, overlapping community structure, but higher-order Markov chain models suffer from the curse of dimensionality: their vast parameter spaces require exponentially increasing data to avoid overfitting and therefore make mapping inefficient already for moderate-sized systems. To overcome this problem, we introduce an efficient cross-validated mapping approach based on network flows modeled by sparse Markov chains. To illustrate our approach, we present a map of citation flows in science with research fields that overlap in multidisciplinary journals. Compared...

  6. Solidification structures grown under induced flow and continuous casting of steel

    Tsavaras, A. A.


    The use of induced flow as a means to control solidification structures in strand cast steel is investigated. The quality problems in strand cast steel stemming from columnar growth can be partially controlled, by Electro Magnetic Stirring (EMS). Induced flow changes the normal morphology of dendrites. Solids grown under intense stirring conditions show both negative and positive segregation which is considered unacceptable by some steel producers. The inclusion size and population is strongly affected by induced flow (EMS). Laboratory and industrial data show substantial reduction in inclusion size and content, but the overall effect of flow on inclusions is affected by the particular type of flow patterns utilized in each case. Productivity and quality are raised substantially in steel strand casting by utilizing EMS.

  7. Disinfection of an advanced primary effluent with peracetic acid and ultraviolet combined treatment: a continuous-flow pilot plant study.

    González, Abelardo; Gehr, Ronald; Vaca, Mabel; López, Raymundo


    Disinfection of an advanced primary effluent using a continuous-flow combined peracetic acid/ultraviolet (PAA/UV) radiation system was evaluated. The purpose was to determine whether the maximum microbial content, established under Mexican standards for treated wastewaters meant for reuse--less than 240 most probable number fecal coliforms (FC)/100 mL--could be feasibly accomplished using either disinfectant individually, or the combined PAA/UV system. This meant achieving reduction of up to 5 logs, considering initial concentrations of 6.4 x 10(+6) to 5.8 x 10(+7) colony forming units/100 mL. During the tests performed under these experiments, total coliforms (TC) were counted because FC, at the most, will be equal to TC. Peracetic acid disinfection achieved less than 1.5 logs TC reduction when the C(t) x t product was less than 2.26 mg x minimum (min)/L; 3.8 logs for C(t) x t 4.40 mg x min/L; and 5.9 logs for C(t) x t 24.2 mg x min/L. In continuous-flow UV irradiation tests, at a low-operating flow (21 L/min; conditions which produced an average UV fluence of 13.0 mJ/cm2), the highest TC reduction was close to 2.5 logs. The only condition that produced a disinfection efficiency of approximately 5 logs, when both disinfection agents were used together, was the combined process dosing 30 mg PAA/L at a pilot plant flow of 21 L/min and contact time of 10 minutes to attain an average C(t) x t product of 24.2 mg x min/L and an average UV fluence of 13 mJ/cm2. There was no conclusive evidence of a synergistic effect when both disinfectants were employed in combination as compared to the individual effects achieved when used separately, but this does not take into account the nonlinearity (tailing-off) of the dose-response curve.

  8. The Vertical Structure of Shallow Water Flow in the Surf Zone and Inner Shelf


    E. Richardson, 2008, Field verification of a CFD model for wave transformation and breaking in the surf zone, J. Waterw. Port Coastal Engrg., 134(2...The Vertical Structure of Shallow Water Flow in the Surf Zone and Inner Shelf Dr. Thomas C. Lippmann Center for Coastal...wave- and tidally-driven shallow water flows in the shallow depths of the inner shelf and surf zone. OBJECTIVES 1. Theoretical investigations of

  9. Simulation of Turbulent Flow in a Complex Passage with a Vibrating Structure by Finite Element Formulations

    Zhang, L. X.; Guo, Y.

    A modeling of the turbulent flow in a complex passage with dynamical fluid-structure interaction (FSI) is established on the generalized variational principle. A monolithic coupling method on the finite element formulations (FEM) is used to realize numerical computation of the flow with dynamical FSI. The comparisons with LES show that the results on the FEM formulations suggested in this paper are favorable, and the computing effort is economical.

  10. SAUNA: A system for grid generation and flow simulation using hybrid structured/unstructured grids

    Childs, P. N.; Shaw, J. A.; Peace, A. J.; Georgala, J. M.


    The development of a flow simulation facility for predicting the aerodynamics of complex configurations wherein the grid is composed of both structured and unstructured regions is described. Issues relating to the generation and analysis of such grids and to the accurate and efficient computation of both inviscid and viscous flows thereon are considered. Further the development of a comprehensive post-processing and visualization facility is explored. Techniques are illustrated throughout by application to realistic aircraft geometries.


    Ning Yang; Wei Wang; Wei Ge; Jinghai Li


    @@ Introduction Gas-solid two-phase flow is often encountered in chemical reactors for the process industry. For industrial users, design, scale-up, control and optimization for these reactors require a good understanding of the hydrodynamics of gas-solid two-phase flow. For researchers, exploration and prediction of the complex phenomena call for a good comprehension of the heterogeneous structure and of the dominant mechanisms of gas-solid and solid-solid interactions.


    NING Li-zhong; YOSHIFUMI Harada; HIDEO Yahata; LI Jian-zhong


    The convection structure in a rectangular channel with a horizontal flow forΓ= 12 was studied. The simulations were preformed by solving the hydrodynamic equations using the SIMPLE method. The convective behavior in an absolutely and convectively unstable regime was studied. The results show that the two types of convection patterns in this system appear depending on the convection intensity and horizontal flow. A periodically localized traveling wave state was found in this system.

  13. The feasible study of the water flow in the micro channel with the Y-junction and narrow structure for various flow rates

    Jasikova D.


    Full Text Available Here we present the results of measurement in micro-channel with the Y-junction and narrow structure for various flow rates. There was used BSG micro-channel with trapezoidal cross-section. The parameters of the channel are described in the paper. The flow in the micro-channel was invested with micro-PIV technique and various flow rates were set on each inlet. The resulting flow rate in the steady area follows the laminar flow with very low Re 30. Here we are focused on the flow characteristic in the Y-junction and in selected narrow structure. The fluid flow is evaluated with vector and scalar maps and the profile plots that were taken in the point of interest.

  14. Regional structural differences across functionally parcellated Brodmann areas of human primary somatosensory cortex.

    Sánchez-Panchuelo, Rosa-María; Besle, Julien; Mougin, Olivier; Gowland, Penny; Bowtell, Richard; Schluppeck, Denis; Francis, Susan


    Ultra-high-field (UHF) MRI is ideally suited for structural and functional imaging of the brain. High-resolution structural MRI can be used to map the anatomical boundaries between functional domains of the brain by identifying changes related to the pattern of myelination within cortical gray matter, opening up the possibility to study the relationship between functional domains and underlying structure in vivo. In a recent study, we demonstrated the correspondence between functional (based on retinotopic mapping) and structural (based on changes in T2(⁎)-weighted images linked to myelination) parcellations of the primary visual cortex (V1) in vivo at 7T (Sanchez-Panchuelo et al., 2012b). Here, we take advantage of the improved BOLD CNR and high spatial resolution achievable at 7T to study regional structural variations across the functionally defined areas within the primary somatosensory cortex (S1) in individual subjects. Using a traveling wave fMRI paradigm to map the internal somatotopic representation of the index, middle, and ring fingers in S1, we were able to identify multiple map reversals at the tip and base, corresponding to the boundaries between Brodmann areas 3a, 3b, 1 and 2. Based on high resolution structural MRI data acquired in the same subjects, we inspected these functionally-parcellated Brodmann areas for differences in cortical thickness and MR contrast measures (magnetization transfer ratio (MTR) and signal intensity in phase sensitive inversion recovery (PSIR) images) that are sensitive to myelination. Consistent area-related differences in cortical thickness and MTR/PSIR measurements were found across subjects. However these measures did not have sufficient sensitivity to allow definition of areal boundaries.

  15. 'SIMPLES': a structured primary care approach to adults with difficult asthma.

    Ryan, Dermot; Murphy, Anna; Ställberg, Björn; Baxter, Noel; Heaney, Liam G


    The substantial majority of patients with asthma can expect minimal breakthrough symptoms on standard doses of inhaled corticosteroids with or without additional add-on therapies. SIMPLES is a structured primary care approach to the review of a person with uncontrolled asthma which encompasses patient education monitoring, lifestyle and pharmacological management and addressing support needs which will achieve control in most patients. The small group of patients presenting with persistent asthma symptoms despite being prescribed high levels of treatment are often referred to as having 'difficult asthma'. Some will have difficult, 'therapy resistant' asthma, some will have psychosocial problems which make it difficult for them to achieve asthma control and some may prove to have an alternative diagnosis driving their symptoms. A few patients will benefit from referral to a 'difficult asthma' clinic. The SIMPLES approach, aligned with close co-operation between primary and specialist care, can identify this patient group, avoid inappropriate escalation of treatment, and streamline clinical assessment and management.

  16. 3D study of the structure of primary crystals in a rheocast Al-Cu alloy

    Niroumand, B.; Xia, K. [Melbourne Univ., Parkville, Vic. (Australia). Dept. of Mech. and Manuf. Eng.


    An Al-10.25 wt.% Cu alloy was mechanically stirred at 1000 rpm while being cooled to and isothermally held at 619 C for various times before casting. The microstructure of as-cast materials consists of pseudo-particles and pseudo-clusters in two-dimensional (2D) views. Serial sectioning was performed and it was found that pseudo-particles belonging to a pseudo-cluster were connected in three dimensions and a pseudo-cluster was actually a single primary particle. A three dimensional (3-D) model of such a primary particle was constructed from 2D sections which showed the complexity of its structure. It is suggested that the theories based on agglomeration and disagglomeration of particles during rheocasting be re-examined in light of the experimental results. (orig.)

  17. Vertical flows and structures excited by magnetic activity in the Galactic center region

    Kakiuchi, Kensuke; Fukui, Yasuo; Torii, Kazufumi; Machida, Mami; Matsumoto, Ryoji


    The vertical flow structure in the galactic center region remains poorly understood. We analyzed the MHD simulation data by Suzuki et al. (2015) for better understanding. As a result, we found the fast downflows with a speed of ~100 km/s near the foot-points of magnetic loops. These downflows are flowing along a magnetic field line and accelerated by the gravity. The direction of the fast flows is changed by the magnetic loop geometry, as it moves. As a result, not only vertical motions but also azimuthal and radial motions are excited. This feature could be relevant to the observed high velocity dispersion in the position-velocity diagram.

  18. Multi-scale symbolic time reverse analysis of gas-liquid two-phase flow structures

    Wang, Hongmei; Zhai, Lusheng; Jin, Ningde; Wang, Youchen

    Gas-liquid two-phase flows are widely encountered in production processes of petroleum and chemical industry. Understanding the dynamic characteristics of multi-scale gas-liquid two-phase flow structures is of great significance for the optimization of production process and the measurement of flow parameters. In this paper, we propose a method of multi-scale symbolic time reverse (MSTR) analysis for gas-liquid two-phase flows. First, through extracting four time reverse asymmetry measures (TRAMs), i.e. Euclidean distance, difference entropy, percentage of constant words and percentage of reversible words, the time reverse asymmetry (TRA) behaviors of typical nonlinear systems are investigated from the perspective of multi-scale analysis, and the results show that the TRAMs are sensitive to the changing of dynamic characteristics underlying the complex nonlinear systems. Then, the MSTR analysis is used to study the conductance signals from gas-liquid two-phase flows. It is found that the multi-scale TRA analysis can effectively reveal the multi-scale structure characteristics and nonlinear evolution properties of the flow structures.

  19. Large-eddy structures of turbulent swirling flows and methane-air swirling diffusion combustion

    Liyuan Hu; Lixing Zhou; Jian Zhang; Keren Wang


    Turbulent swirling flows and methane-air swirling diffusion combustion are studied by large-eddy simulation (LES) using a Smagorinsky-Lilly subgrid scale turbulence model and a second-order moment (SOM) SGS combustion model, and also by RANS modeling using the Reynolds Stress equation model with the IPCM+wall and IPCM pressure-strain models and SOM combustion model. The LES statistical results for swirling flows give good agreement with the experimental results, indicating that the adopted subgrid-scale turbulence model is suitable for swirling flows.The LES instantaneous results show the complex vortex shedding pattern in swirling flows. The initially formed large vortex structures soon break up in swirling flows. The LES statistical results of combustion modeling are near the experimental results and are as good as the RANS-SOM modeling results. The LES results show that the size and range of large vortex structures in swirling combustion are different from those of isothermal swirling flows, and the chemical reaction is intensified by the large-eddy vortex structures.

  20. Dynamic structures of bubble-driven liquid flows in a cylindrical tank

    Kim, Ju Sang [Pusan National University, School of Mechanical Engineering, Busan (Korea, Republic of); LG Electronics Co., Changwon (Korea, Republic of); Kim, Sang Moon [Doosan Heavy Industry and Construction, Changwon (Korea, Republic of); Kim, Hyun Dong; Ji, Ho Seong; Kim, Kyung Chun [Pusan National University, School of Mechanical Engineering, Busan (Korea, Republic of)


    The spatial and temporal structures of turbulent water flows driven by air bubbles in a cylindrical tank were investigated. The time-resolved particle image velocimetry technique was adopted for quantitative visualization. Flow rates of compressed air were changed from 1 to 5 L/min at 0.5 MPa, and the corresponding range of bubble-based Reynolds number (Re) ranged from 8,300 to 21,100. The dynamics of flow structures was further investigated by the time-resolved proper orthogonal decomposition analysis technique. With increasing Re, mean velocity fields driven by the rising bubbles are almost same, but turbulence is dramatically enhanced. Both spatial and temporal modes were quite different with respect to the air flow rates. Three most dominant spatial structures are recirculating flow, bubble-induced motion, and sloshing of free surface, the bigger the latter the higher Re. We found the frequency of sloshing motion from flow visualization and the FFT analysis of temporal modes. (orig.)

  1. Comparison between "Poissonian" and "mechanically-oriented" DFN models for predicting flow structure and permeability.

    Maillot, J.; Davy, P.; De Dreuzy, J. R.; Le Goc, R.; Darcel, C.


    A major use of Discrete Fracture Network models (DFN) is to evaluate permeability and flow structure in hardrock aquifers from geological observations of fracture networks. Although extensively studied, there has been little interest in the spatial structure of DFN models, generally assumed to be Poissonian, i.e. spatially random. In this paper, we compare the results of Poissonian DFN to new DFN models where fractures result from a growth process defined by simplified rules for nucleation, growth and fracture arrest. This 'mechanical' model is characterized by a large proportion of T-intersections, and a distribution of the number of intersections per fracture models from Poissonian DFN. Flow distributions and permeability were calculated for 3D networks with up to 1,200 fractures and power-law fracture length distributions. For the same statistical properties in orientation and density, the permeability is significantly smaller in mechanical models than in their Poissonian equivalent, with ratios between 3 and >10. We estimate flow channeling by calculating the participation ratio of the distribution of flow per fracture (Pf), which gives the number of fractures that carry a significant part of the flow. Pf is much larger for Poissonian model than for mechanical ones. Moreover we find that permeability scales linearly with Pf, illustrating the close relationship between the geological structure, flow structure, and permeability. In most of hardrock aquifers (illustrated with examples from Sweden), the density of fracture is about a few fractures per meter, while the flow localizes in a few channels at the kilometric scale. There are several reasons why channeling is so extreme, including a large distribution of fracture transmissivities, but this observation also questions the use of Poissonian models in describing the actual fracture network structure.

  2. Ordering of small particles in one-dimensional coherent structures by time-periodic flows

    Pushkin, Dmitri; Shevtsova, Valentina


    Small particles transported by a fluid medium do not necessarily have to follow the flow. We show that for a wide class of time-periodic incompressible flows inertial particles have a tendency to spontaneously align in one-dimensional dynamic coherent structures. This effect may take place for particles so small that often they would be expected to behave as passive tracers and be used in PIV measurement technique. We link the particle tendency to form one-dimensional structures to the nonlinear phenomenon of phase locking. We propose that this general mechanism is, in particular, responsible for the enigmatic formation of the `particle accumulation structures' discovered experimentally in thermocapillary flows more than a decade ago and unexplained until now.

  3. Development of a flow structure interaction methodology applicable to a convertible car roof

    Knight, J J


    The current research investigates the flow-induced deformation of a convertible roof of a vehicle using experimental and numerical methods. A computational methodology is developed that entails the coupling of a commercial Computational Fluid Dynamics (CFD) code with an in-house structural code. A model two-dimensional problem is first studied. The CFD code and a Source Panel Method (SPM) code are used to predict the pressure acting on the surface of a rigid roof of a scale model. Good agreement is found between predicted pressure distribution and that obtained in a parallel wind-tunnel experimental programme. The validated computational modelling of the fluid flow is then used in a coupling strategy with a line-element structural model that incorporates initial slackness of the flexible roof material. The computed flow-structure interaction yields stable solutions, the aerodynamically loaded flexible roof settling into static equilibrium. The effects of slackness and material properties on deformation and co...

  4. Cross-Diffusion Systems with Excluded-Volume Effects and Asymptotic Gradient Flow Structures

    Bruna, Maria; Burger, Martin; Ranetbauer, Helene; Wolfram, Marie-Therese


    In this paper, we discuss the analysis of a cross-diffusion PDE system for a mixture of hard spheres, which was derived in Bruna and Chapman (J Chem Phys 137:204116-1-204116-16, 2012a) from a stochastic system of interacting Brownian particles using the method of matched asymptotic expansions. The resulting cross-diffusion system is valid in the limit of small volume fraction of particles. While the system has a gradient flow structure in the symmetric case of all particles having the same size and diffusivity, this is not valid in general. We discuss local stability and global existence for the symmetric case using the gradient flow structure and entropy variable techniques. For the general case, we introduce the concept of an asymptotic gradient flow structure and show how it can be used to study the behavior close to equilibrium. Finally, we illustrate the behavior of the model with various numerical simulations.

  5. Surface (glyco-)proteins: primary structure and crystallization under microgravity conditions

    Claus, H.; Akca, E.; Schultz, N.; Karbach, G.; Schlott, B.; Debaerdemaeker, T.; De Clercq, J.-P.; König, H.


    The Archaea comprise microorganisms that live under environmental extremes, like high temperature, low pH value or high salt concentration. Their cells are often covered by a single layer of (glyco)protein subunits (S-layer) in hexagonal arrangement. In order to get further hints about the molecular mechanisms of protein stabilization we compared the primary and secondary structures of archaeal S-layer (glyco)proteins. We found an increase of charged amino acids in the S-layer proteins of the extreme thermophilic species compared to their mesophilic counterparts. Our data and those of other authors suggest that ionic interactions, e.g., salt bridges seem to be played a major role in protein stabilization at high temperatures. Despite the differences in the growth optima and the predominance of some amino acids the primary structures of S-layers revealed also a significant degree of identity between phylogenetically related archaea. These obervations indicate that protein sequences of S-layers have been conserved during the evolution from extremely thermophilic to mesophilic life. To support these findings the three-dimensional structure of the S-layer proteins has to be elucidated. Recently, we described the first successful crystallization of an extreme thermophilic surface(glyco)protein under microgravity conditions.

  6. In Silico Analysis of β-Galactosidases Primary and Secondary Structure in relation to Temperature Adaptation

    Vijay Kumar


    Full Text Available β-D-Galactosidases (EC hydrolyze the terminal nonreducing β-D-galactose residues in β-D-galactosides and are ubiquitously present in all life forms including extremophiles. Eighteen microbial β-galactosidase protein sequences, six each from psychrophilic, mesophilic, and thermophilic microbes, were analyzed. Primary structure reveals alanine, glycine, serine, and arginine to be higher in psychrophilic β-galactosidases whereas valine, glutamine, glutamic acid, phenylalanine, threonine, and tyrosine are found to be statistically preferred by thermophilic β-galactosidases. Cold active β-galactosidase has a strong preference towards tiny and small amino acids, whereas high temperature inhabitants had higher content of basic and aromatic amino acids. Thermophilic β-galactosidases have higher percentage of α-helix region responsible for temperature tolerance while cold loving β-galactosidases had higher percentage of sheet and coil region. Secondary structure analysis revealed that charged and aromatic amino acids were significant for sheet region of thermophiles. Alanine was found to be significant and high in the helix region of psychrophiles and valine counters in thermophilic β-galactosidase. Coil region of cold active β-galactosidase has higher content of tiny amino acids which explains their high catalytic efficiency over their counterparts from thermal habitat. The present study has revealed the preference or prevalence of certain amino acids in primary and secondary structure of psychrophilic, mesophilic, and thermophilic β-galactosidase.

  7. Computational Investigation on Fully Developed Periodic Laminar Flow Structure in Baffled Circular Tube with Various BR

    Withada Jedsadaratanachai


    Full Text Available This paper presents a 3D numerical analysis of fully developed periodic laminar flow in a circular tube fitted with 45° inclined baffles with inline arrangement. The computations are based on a finite volume method, and the SIMPLE algorithm has been implemented. The characteristics of fluid flow are presented for Reynolds number, Re = 100–1000, based on the hydraulic diameter (D of the tube. The angled baffles were repeatedly inserted at the middle of the test tube with inline arrangement to generate vortex flows over the tested tube. Effects of different Reynolds numbers and blockage ratios (b/D, BR with a single pitch ratio of 1 on flow structure in the tested tube were emphasized. The flows in baffled tube show periodic flow at x/D ≈ 2-3, and become a fully developed periodic flow profiles at x/D ≈ 6-7, depending on Re, BR and transverse plane positions. The computational results reveal that the higher of BR and closer position of turbulators, the faster of fully developed periodic flow profiles.

  8. Experimental investigation of internal structure of open-channel flow with intense transport of sediment

    Matoušek Václav


    Full Text Available Gravity-driven open-channel flows carrying coarse sediment over an erodible granular deposit are studied. Results of laboratory experiments with artificial sediments in a rectangular tilting flume are described and analyzed. Besides integral quantities such as flow rate of mixture, transport concentration of sediment and hydraulic gradient, the experiments include measurements of the one-dimensional velocity distribution across the flow. A vertical profile of the longitudinal component of local velocity is measured across the vertical axis of symmetry of a flume cross section using three independent measuring methods. Due to strong flow stratification, the velocity profile covers regions of very different local concentrations of sediment from virtually zero concentration to the maximum concentration of bed packing. The layered character of the flow results in a velocity distribution which tends to be different in the transport layer above the bed and in the sediment-free region between the top of the transport layer and the water surface. Velocity profiles and integral flow quantities are analyzed with the aim of evaluating the layered structure of the flow and identifying interfaces in the flow with a developed transport layer above the upper plane bed.

  9. Trophic structure and flows of energy in the Huizache-Caimanero lagoon complex on the Pacific coast of Mexico

    Zetina-Rejón, Manuel J.; Arreguín-Sánchez, Francisco; Chávez, Ernesto A.


    The Huizache-Caimanero coastal lagoon complex on the Pacific coast of Mexico supports an important shrimp fishery and is one of the most productive systems in catch per unit area of this resource. Four other less important fish groups are also exploited. In this study, we integrated the available information of the system into a mass-balance trophic model to describe the ecosystem structure and flows of energy using the E COPATH approach. The model includes 26 functional groups consisting of 15 fish groups, seven invertebrate groups, macrophytes, phytoplankton, and a detritus group. The resulting model was consistent as indicated by the output parameters. According to the overall pedigree index (0.75), which measures the quality of the input data on a scale from 0 to 1, it is a high quality model. Results indicate that zooplankton, microcrustaceans, and polychaetes are the principal link between trophic level (TL) one (primary producers and detritus) and consumers of higher TLs. Most production from macrophytes flows to detritus, and phytoplankton production is incorporated into the food web by zooplankton. Half of the flow from TL one to the next level come from detritus, which is an important energy source not only for several groups in the ecosystem but also for fisheries, as shown by mixed trophic impacts. The Huizache-Caimanero complex has the typical structure of tropical coastal lagoons and estuaries. The TL of consumers ranges from 2.0 to 3.6 because most groups are composed of juveniles, which use the lagoons as a nursery or protection area. Most energy flows were found in the lower part of the trophic web.

  10. Inferred vs realized patterns of gene flow: an analysis of population structure in the Andros Island Rock Iguana.

    Giuliano Colosimo

    Full Text Available Ecological data, the primary source of information on patterns and rates of migration, can be integrated with genetic data to more accurately describe the realized connectivity between geographically isolated demes. In this paper we implement this approach and discuss its implications for managing populations of the endangered Andros Island Rock Iguana, Cyclura cychlura cychlura. This iguana is endemic to Andros, a highly fragmented landmass of large islands and smaller cays. Field observations suggest that geographically isolated demes were panmictic due to high, inferred rates of gene flow. We expand on these observations using 16 polymorphic microsatellites to investigate the genetic structure and rates of gene flow from 188 Andros Iguanas collected across 23 island sites. Bayesian clustering of specimens assigned individuals to three distinct genotypic clusters. An analysis of molecular variance (AMOVA indicates that allele frequency differences are responsible for a significant portion of the genetic variance across the three defined clusters (Fst =  0.117, p<<0.01. These clusters are associated with larger islands and satellite cays isolated by broad water channels with strong currents. These findings imply that broad water channels present greater obstacles to gene flow than was inferred from field observation alone. Additionally, rates of gene flow were indirectly estimated using BAYESASS 3.0. The proportion of individuals originating from within each identified cluster varied from 94.5 to 98.7%, providing further support for local isolation. Our assessment reveals a major disparity between inferred and realized gene flow. We discuss our results in a conservation perspective for species inhabiting highly fragmented landscapes.

  11. Wake structure of an oscillating cylinder in a flowing soap film

    Stremler, Mark; Yang, Wenchao


    When a circular cylinder oscillates with respect to a uniform background flow, a variety of wake patterns can be observed in which multiple vortices are generated during each shedding cycle. Thorough investigations of the possible wake patterns behind a cylinder undergoing forced oscillations have been conducted by C.H.K. Williamson using two-dimensional characterization of a three-dimensional flow. Attempts to reproduce the structural bifurcations using two-dimensional computational models have been only moderately successful. A flowing soap film, an experimental system with quasi-two-dimensional flow, provides an alternative method for investigating the role of system dimensionality in the structure and dynamics of complex vortex wakes. Wake patterns are observed directly through interference fringes caused by thickness variations in the soap film. Such systems have been used for decades to visualize wake structure, but they have not previously been used to conduct an analog of Williamson's work. We will discuss the results of an ongoing parametric study of the wake structure produced by a circular cylinder undergoing forced oscillations transverse to the background flow in an inclined soap film system.

  12. Influence of laminar flow on preorientation of coal tar pitch structural units: Raman microspectroscopic study

    Urban, O.; Jehlička, J.; Pokorný, J.; Rouzaud, J. N.


    In order to estimate the role of laminar flow of viscous, aromatic matter of carbonaceous precursor on microtextural preorientation in pregraphitization stage, we performed experiments with coal tar pitch (CTP). The principal hypothesis of preorientation of basic structural units (BSUs) in the case of laminar flow (pressure impregnation of CTP into porous matrix) and secondary release of volatiles during carbonization were studied. Glass microplates, planar porous medium with average distance between single microplates 5 μm were used as suitable porous matrix. Samples of CTP were carbonized up to 2500 °C. Optical microscopy reveals large flow domains in the sample of cokes carbonized between glass microplates. Raman microspectroscopy and high resolution transmission electron microscopy (HRTEM) show that at nanometric scale, the samples do not support the proposed hypotheses. With increasing temperature of pyrolysis, the graphitization of CTP impregnated into porous matrix proceeds to lower degree of structural ordering in comparison with single pyrolyzed CTP. This is explained by the release of volatile matter during carbonization in geometrically restricted spaces. More evident structural changes were discovered with the sample of single coke, where parts of fine grain mosaics, relicts of 'so called QI parts', reveal higher structural organization, in comparison with large and prolonged flow domains, similar to flow domains of cokes from microplates.

  13. PIV measurement of the vertical cross-flow structure over tube bundles

    Iwaki, C.; Cheong, K. H.; Monji, H.; Matsui, G.

    Shell and tube heat exchangers are among the most commonly used types of heat exchangers. Shell-side cross-flow in tube bundles has received considerable attention and has been investigated extensively. However, the microscopic flow structure including velocity distribution, wake, and turbulent structure in the tube bundles needs to be determined for more effective designs. Therefore, in this study, in order to clarify the detailed structure of cross-flow in tube bundles with particle image velocimetry (PIV), experiments were conducted using two types of model; in-line and staggered bundles with a pitch-to-diameter ratio of 1.5, containing 20 rows of five 15 mm O.D. tubes in each row. The velocity data in the whole flow field were measured successfully by adjusting the refractive index of the working fluid to that of the tube material. The flow features were characterized in different tube bundles with regards to the velocity vector field, vortex structure, and turbulent intensity.

  14. Effect of primary particle morphology on the structure of gels formed in intense turbulent shear.

    Arosio, Paolo; Xie, Delong; Wu, Hua; Braun, Leonie; Morbidelli, Massimo


    We study the effect of primary particle morphology on intense shear-induced gelation without adding electrolytes. The primary particles are composed of a rubbery core grafted with a polystyrene shell. Depending on the shell-to-core mass ratio, the core can be partially covered by the shell, leading to strawberry-like morphology. It is found that at a fixed core mass the fractal dimension of the clusters constructing the gel decreases (i.e., more open cluster structure) as the shell mass increases, until reaching a plateau. The SEM pictures of the gels reveal that the structure variations are due to the occurrence of partial coalescence among particles, which decreases as the shell mass increases. In the region where the fractal dimension reaches a plateau, the coalescence is negligible. The conversion of the primary particles to gels is incomplete and increases as the extent of coalescence decreases. This is related to the fact that the smaller the extent of coalescence, the larger the cluster size. Thus, because of its cubic dependence on the cluster size, the aggregation rate increases as the extent of coalescence decreases, leading to increased conversion. It is therefore evident that the key parameter controlling the gel structure and the particle conversion is the core surface coverage by the shell. To further verify this conclusion, we have carried out the shear-induced gelation of another set of particles with varying core mass. It is found that the only parameter that can well correlate the values of the fractal dimension and particle conversion from the two sets of particles is the core surface coverage.

  15. Imaging dendritic spines of rat primary hippocampal neurons using structured illumination microscopy.

    Schouten, Marijn; De Luca, Giulia M R; Alatriste González, Diana K; de Jong, Babette E; Timmermans, Wendy; Xiong, Hui; Krugers, Harm; Manders, Erik M M; Fitzsimons, Carlos P


    Dendritic spines are protrusions emerging from the dendrite of a neuron and represent the primary postsynaptic targets of excitatory inputs in the brain. Technological advances have identified these structures as key elements in neuron connectivity and synaptic plasticity. The quantitative analysis of spine morphology using light microscopy remains an essential problem due to technical limitations associated with light's intrinsic refraction limit. Dendritic spines can be readily identified by confocal laser-scanning fluorescence microscopy. However, measuring subtle changes in the shape and size of spines is difficult because spine dimensions other than length are usually smaller than conventional optical resolution fixed by light microscopy's theoretical resolution limit of 200 nm. Several recently developed super resolution techniques have been used to image cellular structures smaller than the 200 nm, including dendritic spines. These techniques are based on classical far-field operations and therefore allow the use of existing sample preparation methods and to image beyond the surface of a specimen. Described here is a working protocol to apply super resolution structured illumination microscopy (SIM) to the imaging of dendritic spines in primary hippocampal neuron cultures. Possible applications of SIM overlap with those of confocal microscopy. However, the two techniques present different applicability. SIM offers higher effective lateral resolution, while confocal microscopy, due to the usage of a physical pinhole, achieves resolution improvement at the expense of removal of out of focus light. In this protocol, primary neurons are cultured on glass coverslips using a standard protocol, transfected with DNA plasmids encoding fluorescent proteins and imaged using SIM. The whole protocol described herein takes approximately 2 weeks, because dendritic spines are imaged after 16-17 days in vitro, when dendritic development is optimal. After completion of the

  16. Minimizing endoscopic thoracic sympathectomy for primary palmar hyperhidrosis: guided by palmar skin temperature and laser Doppler blood flow.

    Li, Xu; Tu, Yuan-Rong; Lin, Min; Lai, Fan-Cai; Chen, Jian-Feng; Miao, Hui-Weng


    Limiting the extent of sympathectomy in palmar hyperhidrosis was recently recognized as an effective method to minimize the incidence and severity of troublesome compensatory sweating. However, the levels at which transection should be performed remain controversial. In this study, we proposed that the level of ablation varies and should be adjusted for each individual patient. Guided by palmar skin temperature and laser Doppler blood flow, we try to find the correct target level in each case. Fifty patients with severe primary palmar hyperhidrosis received bilateral endoscopic thoracic sympathectomy. Different levels of transection from T4 to T2 were performed step by step until the successful extirpation was implied by the intraoperative monitoring. The results of the operations were studied. All patients were followed up and evaluated for symptom resolution, postoperative complication, levels of satisfaction, and severity of compensatory sweating. Of a total of 100 lateral procedures, 76 laterals (76%) ended the procedure at the T4 level, 23 laterals (23%) ended the procedure at the T3 level, and 1 lateral (1%) ended the procedure at the T2 level. The postoperative complication was minor, and no Horner's syndrome was detected. The rate of symptom resolution was 100% and no recurrence was found. The satisfaction rate was 92%, and the incidence of mild, moderate, and severe compensatory sweating were 12%, 8%, and 6%, respectively. Concerning the sympathectomy for palmar hyperhidrosis, there is a possibility that the level of the transection varies and should be adjusted for each individual patient. Intraoperative monitoring of temperature and blood flow may be a useful tool in establishing a kind of standardized reference for finding the correct target level.

  17. Reduced coronary flow reserve in patients with primary hyperparathyroidism: a study by G-SPECT myocardial perfusion imaging

    Marini, Cecilia [CNR Institute of Bioimages and Molecular Physiology Milan, Genoa (Italy); Giusti, Massimo; Vera, Lara; Minuto, Francesco [University of Genoa, Department of Endocrinological and Metabolic Sciences, Genoa (Italy); Armonino, Riccardo; Ghigliotti, Giorgio; Bezante, Gian Paolo; Morbelli, Silvia; Pomposelli, Elena; Massollo, Michela; Gandolfo, Patrizia; Sambuceti, Gianmario [University of Genoa, Department of Internal Medicine, Genoa (Italy)


    The mechanisms underlying increased cardiovascular risk in primary hyperparathyroidism (pHPT) have not been fully defined. Recently, this issue has become the subject of renewed interest due to the increasing evidence that the endothelium and vascular wall are targets for parathyroid hormone (PTH). The aim of this study was to measure regional coronary flow reserve (CFR) to determine whether the vascular damage induced by pHPT extends to affect the coronary microvascular function. A total of 22 pHPT patients without a history of coronary artery disease and 7 age-matched control subjects were recruited. Dipyridamole myocardial blood flow (MBF) was assessed using {sup 99m}Tc-sestamibi by measuring first-transit counts in the pulmonary artery and myocardial count rate from G-SPECT images. Baseline MBF was estimated 2 h later according to the same procedure. Regional CFR was defined as the ratio between dipyridamole and baseline MBF using a 17-segment left ventricular model. Three pHPT patients showed reversible perfusion defects and were excluded from the analysis. In the remaining 19, CFR was significantly lower with respect to the control subjects (1.88 {+-} 0.64 vs. 3.36 {+-} 0.66, respectively; p < 0.01). Moreover, patients studied for more than 28 months from pHPT diagnosis showed lower CFR values than the others (1.42 {+-} 0.18 vs. 2.25 {+-} 0.64, respectively; p < 0.01). Consequently, the time from diagnosis to the nuclear study showed a reasonable correlation with the degree of CFR impairment (Spearman's rho -0.667, p < 0.02). pHPT is associated with a significant dysfunction of the coronary microcirculation. This disorder might contribute to the high cardiovascular risk of conditions characterized by chronic elevations in serum PTH levels. (orig.)

  18. Asymmetrical flow field-flow fractionation with multi-angle light scattering detection for the analysis of structured nanoparticles.

    Zattoni, Andrea; Rambaldi, Diana Cristina; Reschiglian, Pierluigi; Melucci, Manuela; Krol, Silke; Garcia, Ana Maria Coto; Sanz-Medel, Alfredo; Roessner, Dierk; Johann, Christoph


    Synthesis and applications of new functional nanoparticles are topics of increasing interest in many fields of nanotechnology. Chemical modifications of inorganic nanoparticles are often necessary to improve their features as spectroscopic tracers or chemical sensors, and to increase water solubility and biocompatibility for applications in nano-biotechnology. Analysis and characterization of structured nanoparticles are then key steps for their synthesis optimization and final quality control. Many properties of structured nanoparticles are size-dependent. Particle size distribution analysis then provides fundamental analytical information. Asymmetrical flow field-flow fractionation (AF4) with multi-angle light scattering (MALS) detection is able to size-separate and to characterize nanosized analytes in dispersion. In this work we focus on the central role of AF4-MALS to analyze and characterize different types of structured nanoparticles that are finding increasing applications in nano-biotechnology and nanomedicine: polymer-coated gold nanoparticles, fluorescent silica nanoparticles, and quantum dots. AF4 not only size-fractionated these nanoparticles and measured their hydrodynamic radius (r(h)) distribution but it also separated them from the unbound, relatively low-M(r) components of the nanoparticle structures which were still present in the sample solution. On-line MALS detection on real-time gave the gyration radius (r(g)) distribution of the fractionated nanoparticles. Additional information on nanoparticle morphology was then obtained from the r(h)/r(g) index. Stability of the nanoparticle dispersions was finally investigated. Aggregation of the fluorescent silica nanoparticles was found to depend on the concentration at which they were dispersed. Partial release of the polymeric coating from water-soluble QDs was found when shear stress was induced by increasing flowrates during fractionation.

  19. Primary structure of the plant serpin BSZ7 having the capacity of chymotrypsin inhibition

    Rasmussen, Søren K; Klausen, Janne; Hejgaard, Jørn


    The primary structure of barley grain serpin BSZ7 was deduced from a cDNA encoding 397 amino-acid residues. More than 70% of the residues were confirmed by sequencing peptide fragments. The N-terminus was identified as an acetylated Ala by using mass spectrometry coupled with amino-acid analysis....... None of the four putative N-glycosylation sites were found to be glycosylated. The positional identity of BSZ7 with plant and mammalian serpins is 69-72% and 25-32%, respectively....

  20. The primary structure of ammodytin L, a myotoxic phospholipase A2 homologue from Vipera ammodytes venom.

    Krizaj, I; Bieber, A L; Ritonja, A; Gubensek, F


    A new myotoxic phospholipase A2 homologue, having a serine residue in position 49 instead of highly conserved aspartic acid, was found in the venom of Vipera ammodytes. The primary structure revealed additional mutations in the positions important for enzymatic activity. Tyr28 is exchanged for a histidine and Gly33 for asparagine. These changes render earlier-reported weak enzymatic activity unlikely. The role of this rather abundant venom fraction is apparently in myotoxicity, which was confirmed in the muscle-cell culture from neonatal rats. The muscle-cell culture proved to be a good tool to investigate the effects of various myotoxins on muscle cells.

  1. Experimental investigation of system parameters and structure influence on steam-water flow regime and pressure oscillation

    Proskouriakov, K. N.; Moukhine, V. S.; Sabouni, Kh. [Moscow Power Engineering Institute, Moscow (Russian Federation)


    Primary circuit of heat removal from reactors are the complex multi loop back spatial systems which are carrying out the main tasks- maintenance of reliable heat removal at normal operating in design modes and minimization of consequences of abnormal and emergency operation. For a substantiation serviceability of these systems out specially developed computer codes are used. These calculations of thermal hydraulic processes are based on use of laws of preservation and drawing up of power balances for the consecutive elements forming a contour of a heat-removal path. Comparisons of the result assumed on the basis of calculation with use of computer codes to the date of experiments show, that in the certain time period in system of cooling there are fluctuation of pressure and flow rate which are not described by model of system used in code. Synchronous investigation of statistic behavior of signals from Resistance Transducer (RT) of vapor content and Pressure Pulses Transducer (PPT) was provided. There was discovered variations of statistical performance of pressure pulsation on condition of different vapor content and flow regime. System parameters and structure influence on steam-water flow regime and pressure oscillation are discussed.

  2. Identifying Structural Flow Defects in Disordered Solids Using Machine-Learning Methods

    Cubuk, E. D.; Schoenholz, S. S.; Rieser, J. M.; Malone, B. D.; Rottler, J.; Durian, D. J.; Kaxiras, E.; Liu, A. J.


    We use machine-learning methods on local structure to identify flow defects—or particles susceptible to rearrangement—in jammed and glassy systems. We apply this method successfully to two very different systems: a two-dimensional experimental realization of a granular pillar under compression and a Lennard-Jones glass in both two and three dimensions above and below its glass transition temperature. We also identify characteristics of flow defects that differentiate them from the rest of the sample. Our results show it is possible to discern subtle structural features responsible for heterogeneous dynamics observed across a broad range of disordered materials.

  3. Flux-flow resistivity in UPt3: Evidence for nonsingular vortex-core structure

    Lütke-Entrup, N.; Blaauwgeers, R.; Plaçais, B.; Huxley, A.; Kambe, S.; Krusius, M.; Mathieu, P.; Simon, Y.


    We have investigated the core structure of B-phase vortex lines in two clean UPt3 crystals, using flux-flow dissipation as the probe. The flux-flow resistivity is determined from the skin depth of the high-frequency oscillations of the vortex lines in the pinned state. With Ĥ⊥ĉ, our data agree with the previously established scaling law of the moderately clean limit with anisotropic gap. When Ĥ||ĉ, the resistivity is three times larger. We interpret this increase as evidence for a vortex-core structure with two length scales, as predicted for UPt3 with a two-component order parameter.

  4. Self-organization of ULF electromagnetic wave structures in the shear flow driven dissipative ionosphere

    G. Aburjania


    Full Text Available This work is devoted to investigation of nonlinear dynamics of planetary electromagnetic (EM ultra-low-frequency wave (ULFW structures in the rotating dissipative ionosphere in the presence of inhomogeneous zonal wind (shear flow. Planetary EM ULFW appears as a result of interaction of the ionospheric medium with the spatially inhomogeneous geomagnetic field. The shear flow driven wave perturbations effectively extract energy of the shear flow increasing own amplitude and energy. These perturbations undergo self organization in the form of the nonlinear solitary vortex structures due to nonlinear twisting of the perturbation's front. Depending on the features of the velocity profiles of the shear flows the nonlinear vortex structures can be either monopole vortices, or dipole vortex, or vortex streets and vortex chains. From analytical calculation and plots we note that the formation of stationary nonlinear vortex structure requires some threshold value of translation velocity for both non-dissipation and dissipation complex ionospheric plasma. The space and time attenuation specification of the vortices is studied. The characteristic time of vortex longevity in dissipative ionosphere is estimated. The long-lived vortices transfer the trapped medium particles, energy and heat. Thus they represent structural elements of turbulence in the ionosphere.

  5. Characterization of Unsteady Flow Structures Around Tandem Cylinders for Component Interaction Studies in Airframe Noise

    Jenkins, Luther N.; Khorrami, Mehdi R.; Choudhari, Meelan M.; McGinley, Catherine B.


    A joint computational and experimental study has been performed at NASA Langley Research Center to investigate the unsteady flow generated by the components of an aircraft landing gear system. Because the flow field surrounding a full landing gear is so complex, the study was conducted on a simplified geometry consisting of two cylinders in tandem arrangement to isolate and characterize the pertinent flow phenomena. This paper focuses on the experimental effort where surface pressures, 2-D Particle Image Velocimetry, and hot-wire anemometry were used to document the flow interaction around the two cylinders at a Reynolds Number of 1.66 x 10(exp 5), based on cylinder diameter, and cylinder spacing-todiameter ratios, L/D, of 1.435 and 3.70. Transition strips were applied to the forward cylinder to produce a turbulent boundary layer upstream of the flow separation. For these flow conditions and L/D ratios, surface pressures on both the forward and rear cylinders show the effects of L/D on flow symmetry, base pressure, and the location of flow separation and attachment. Mean velocities and instantaneous vorticity obtained from the PIV data are used to examine the flow structure between and aft of the cylinders. Shedding frequencies and spectra obtained using hot-wire anemometry are presented. These results are compared with unsteady, Reynolds-Averaged Navier-Stokes (URANS) computations for the same configuration in a companion paper by Khorrami, Choudhari, Jenkins, and McGinley (2005). The experimental dataset produced in this study provides information to better understand the mechanisms associated with component interaction noise, develop and validate time-accurate computer methods used to calculate the unsteady flow field, and assist in modeling of the radiated noise from landing gears.

  6. Secondary flow structure in a model curved artery: 3D morphology and circulation budget analysis

    Bulusu, Kartik V.; Plesniak, Michael W.


    In this study, we examined the rate of change of circulation within control regions encompassing the large-scale vortical structures associated with secondary flows, i.e. deformed Dean-, Lyne- and Wall-type (D-L-W) vortices at planar cross-sections in a 180° curved artery model (curvature ratio, 1/7). Magnetic resonance velocimetry (MRV) and particle image velocimetry (PIV) experiments were performed independently, under the same physiological inflow conditions (Womersley number, 4.2) and using Newtonian blood-analog fluids. The MRV-technique performed at Stanford University produced phase-averaged, three-dimensional velocity fields. Secondary flow field comparisons of MRV-data to PIV-data at various cross-sectional planes and inflow phases were made. A wavelet-decomposition-based approach was implemented to characterize various secondary flow morphologies. We hypothesize that the persistence and decay of arterial secondary flow vortices is intrinsically related to the influence of the out-of-plane flow, tilting, in-plane convection and diffusion-related factors within the control regions. Evaluation of these factors will elucidate secondary flow structures in arterial hemodynamics. Supported by the National Science Foundation under Grant Number CBET-0828903, and GW Center for Biomimetics and Bioinspired Engineering (COBRE). The MRV data were acquired at Stanford University in collaboration with Christopher Elkins and John Eaton.

  7. Laser direct writing 3D structures for microfluidic channels: flow meter and mixer

    Lin, Chih-Lang; Liu, Yi-Jui; Lin, Zheng-Da; Wu, Bo-Long; Lee, Yi-Hsiung; Shin, Chow-Shing; Baldeck, Patrice L.


    The 3D laser direct-writing technology is aimed at the modeling of arbitrary three-dimensional (3D) complex microstructures by scanning a laser-focusing point along predetermined trajectories. Through the perspective technique, the details of designed 3D structures can be properly fabricated in a microchannel. This study introduces a direct reading flow meter and a 3D passive mixer fabricated by laser direct writing for microfluidic applications. The flow meter consists of two rod-shaped springs, a pillar, an anchor, and a wedge-shaped indicator, installed inside a microfluidic channel. The indicator is deflected by the flowing fluid while restrained by the spring to establish an equilibrium indication according to the flow rate. The measurement is readily carried out by optical microscopy observation. The 3D passive Archimedes-screw-shaped mixer is designed to disturb the laminar flow 3D direction for enhancing the mixing efficiency. The simulation results indicate that the screw provides 3D disturbance of streamlines in the microchannel. The mixing demonstration for fluids flowing in the micrchannel approximately agrees with the simulation result. Thanks to the advantage of the laser direct writing technology, this study performs the ingenious applications of 3D structures for microchannels.

  8. Computation of Flow Through Water-Control Structures Using Program DAMFLO.2

    Sanders, Curtis L.; Feaster, Toby D.


    As part of its mission to collect, analyze, and store streamflow data, the U.S. Geological Survey computes flow through several dam structures throughout the country. Flows are computed using hydraulic equations that describe flow through sluice and Tainter gates, crest gates, lock gates, spillways, locks, pumps, and siphons, which are calibrated using flow measurements. The program DAMFLO.2 was written to compute, tabulate, and plot flow through dam structures using data that describe the physical properties of dams and various hydraulic parameters and ratings that use time-varying data, such as lake elevations or gate openings. The program uses electronic computer files of time-varying data, such as lake elevation or gate openings, retrieved from the U.S. Geological Survey Automated Data Processing System. Computed time-varying flow data from DAMFLO.2 are output in flat files, which can be entered into the Automated Data Processing System database. All computations are made in units of feet and seconds. DAMFLO.2 uses the procedures and language developed by the SAS Institute Inc.


    V. V. Myamlin


    Full Text Available Purpose. The article is aimed to improve the methods of car repair organization using the search of rational structures of flexible flows. Methodology. For operation analyses of the car repair flows the simulation modeling was used. The initial data for random value generation of cars repair duration are the statistical data. They were collected at the existing car repair enterprises. Findings. Obtained results show that at the same amount of modules the flexible repair flow is more efficient. Flexible flow increases the working capacity, improves the removal of cars from one module and reduces car detention time in repair. Originality. There were identified the mechanisms, which allow establishing links between the different structural variants of flexible flow and their operational performance. Concrete data that give a fresh look to the organization of car repair production were obtained. Practical value. These results can be used in designing the new perspective enterprises for car repair and also under reconstruction or expansion of existing enterprises in order to transfer them to the flexible flow. It is recommended to incorporate the obtained results and try to put them into production during designing and construction of new car enterprises.

  10. Primary Somatosensory Cortices Contain Altered Patterns of Regional Cerebral Blood Flow in the Interictal Phase of Migraine

    Hodkinson, Duncan J.; Veggeberg, Rosanna; Wilcox, Sophie L.; Scrivani, Steven; Burstein, Rami; Becerra, Lino; Borsook, David


    The regulation of cerebral blood flow (CBF) is a complex integrated process that is critical for supporting healthy brain function. Studies have demonstrated a high incidence of alterations in CBF in patients suffering from migraine with and without aura during different phases of attacks. However, the CBF data collected interictally has failed to show any distinguishing features or clues as to the underlying pathophysiology of the disease. In this study we used the magnetic resonance imaging (MRI) technique—arterial spin labeling (ASL)—to non-invasively and quantitatively measure regional CBF (rCBF) in a case-controlled study of interictal migraine. We examined both the regional and global CBF differences between the groups, and found a significant increase in rCBF in the primary somatosensory cortex (S1) of migraine patients. The CBF values in S1 were positively correlated with the headache attack frequency, but were unrelated to the duration of illness or age of the patients. Additionally, 82% of patients reported skin hypersensitivity (cutaneous allodynia) during migraine, suggesting atypical processing of somatosensory stimuli. Our results demonstrate the presence of a disease-specific functional deficit in a known region of the trigemino-cortical pathway, which may be driven by adaptive or maladaptive functional plasticity. These findings may in part explain the altered sensory experiences reported between migraine attacks. PMID:26372461

  11. Primary Somatosensory Cortices Contain Altered Patterns of Regional Cerebral Blood Flow in the Interictal Phase of Migraine.

    Duncan J Hodkinson

    Full Text Available The regulation of cerebral blood flow (CBF is a complex integrated process that is critical for supporting healthy brain function. Studies have demonstrated a high incidence of alterations in CBF in patients suffering from migraine with and without aura during different phases of attacks. However, the CBF data collected interictally has failed to show any distinguishing features or clues as to the underlying pathophysiology of the disease. In this study we used the magnetic resonance imaging (MRI technique-arterial spin labeling (ASL-to non-invasively and quantitatively measure regional CBF (rCBF in a case-controlled study of interictal migraine. We examined both the regional and global CBF differences between the groups, and found a significant increase in rCBF in the primary somatosensory cortex (S1 of migraine patients. The CBF values in S1 were positively correlated with the headache attack frequency, but were unrelated to the duration of illness or age of the patients. Additionally, 82% of patients reported skin hypersensitivity (cutaneous allodynia during migraine, suggesting atypical processing of somatosensory stimuli. Our results demonstrate the presence of a disease-specific functional deficit in a known region of the trigemino-cortical pathway, which may be driven by adaptive or maladaptive functional plasticity. These findings may in part explain the altered sensory experiences reported between migraine attacks.

  12. Factor structure of the SOCRATES in a sample of primary care patients.

    Maisto, S A; Conigliaro, J; McNeil, M; Kraemer, K; O'Connor, M; Kelley, M E


    Motivation or readiness to change has been studied intensively in recent years in research on the use of brief interventions to change alcohol problems in the primary care setting. The purpose of this study was to investigate the factor structure and concurrent and predictive evidence for validity of the short Stages of Change Readiness and Treatment Eagerness Scale (SOCRATES), a 19-item self-report instrument developed to measure readiness to change alcohol problems in individuals presenting for specialized alcohol treatment. The participants were 210 men and 91 women who were identified as "at-risk" drinkers in 13 community primary care clinics. These individuals completed the SOCRATES and a number of other assessments as part of a preintervention evaluation. A principal components analysis of the SOCRATES data revealed a two-factor structure: a confirmatory factor analysis showed that this structure was a better fit to the data than the three-factor structure that Miller and Tonigan (1996) identified for the SOCRATES. The two factors (9 and 6 items, respectively), seemed to measure perceived degree of severity of an existing alcohol problem (called "Amrec" because it consisted of Miller and Tonigan's ambivalence and recognition items) and taking action to change or to maintain changes in one that exists (called "Taking Steps"). Predictions of significant and nonsignificant correlations between the two derived factors and other baseline variables (alcohol consumption, related problems and symptoms, and demographic factors) generally were confirmed. In addition, baseline Amrec scores were related in predicted directions to 6-month alcohol consumption and related problems data, but the magnitude of these relationships were reduced when other variables that correlated with Amrec or when the 6-month data were taken into account. In general, Taking Steps showed little or no relationship to the 6-month data. The results are compared to previous work with the SOCRATES

  13. Influence of surfactant conditions on the structure of an upward bubbly channel flow

    Ogasawara, Toshiyuki


    We investigated an upward bubbly channel flow and the effects of surfactant on its flow structure experimentally. 3-Pentanol and Triton X-100 are used as surfactants. By the addition of small amount of surfactant, bubble coalescences are prevented and mono-dispersed 1mm spherical bubbles are obtained. Under all of our experimental conditions, the added surfactants do not influence the single-phase turbulence. On the other hand, small amount of surfactant drastically changes the whole flow structure of bubbly flow. On the low concentration of 3-Pentanol (21-63ppm), bubbles strongly migrate towards the wall and these highly accumulated bubbles on the wall form crescent-like shaped horizontal bubble clusters of 10-40mm length. However, in 3-Pentanol solution of higher concentration (˜168ppm) or in the 2ppm Triton X-100 solution, the tendency of the lateral migration of bubbles is weaken and the bubbles are distributed uniformly in the channel. In the surfactant solution, the slip velocity on the bubble surface retards and the bubble rising velocity decreases (Marangoni effect). The change of boundary condition on the bubble surface affects not only drag force but shear-induced lift force. It is indicated that this change of shear-induced lift force greatly relates to the lateral migration of bubbles and the disaggregation of the bubble clusters. We also measured the turbulent properties using LDV and discuss the flow structure.

  14. Effect of the Flow Channel Structure on the Nanofiltration Separation Performance

    Zhi Chen


    Full Text Available Two kinds of newly designed feed channels, for example, a spiral and a serpentine feed channels, for a bench-scale nanofiltration module were developed to improve the filtration performance. The experiments were carried out with the modules using a commercial flat NF membrane to investigate the effects of Reynolds number (Re and flow channel structures on the flux of permeate and Mg2+ rejection. It was shown from the experimental results that although the effects of Reynolds number on fluxes were not obvious for the two new feed channels compared with a normal flow channel structure, the Mg2+ rejections varied apparently with Re. The Mg2+ rejections were almost the same for the modules with two new feed channels and larger than that for the module with normal feed channel. The numerical simulations of fluid flow in the three kinds of feed channels were completed at Re of 4800 to explain the phenomena. The results demonstrated that there was a secondary flow in both new feed channels, which strongly influences the Mg2+ rejection. The rejection increased with increasing average shear stress at the membrane wall. The spiral feed channel was the best one among the flow channel structures investigated.

  15. Fine Structure Zonal Flow Excitation by Beta-induced Alfven Eigenmode

    Qiu, Zhiyong; Zonca, Fulvio


    Nonlinear excitation of low frequency zonal structure (LFZS) by beta-induced Alfven eigenmode (BAE) is investigated using nonlinear gyrokinetic theory. It is found that electrostatic zonal flow (ZF), rather than zonal current, is preferentially excited by finite amplitude BAE. In addition to the well-known meso-scale radial envelope structure, ZF is also found to exhibit fine radial structure due to the localization of BAE with respect to mode rational surfaces. Specifically, the zonal electric field has an even mode structure at the rational surface where radial envelope peaks.

  16. Impacts of temperature on primary productivity and respiration in naturally structured macroalgal assemblages.

    Leigh W Tait

    Full Text Available Rising global temperatures caused by human-mediated change has already triggered significant responses in organismal physiology, distribution and ecosystem functioning. Although the effects of rising temperature on the physiology of individual organisms are well understood, the effect on community-wide processes has remained elusive. The fixation of carbon via primary productivity is an essential ecosystem function and any shifts in the balance of primary productivity and respiration could alter the carbon balance of ecosystems. Here we show through a series of tests that respiration of naturally structured algal assemblages in southern New Zealand greatly increases with rising temperature, with implications for net primary productivity (NPP. The NPP of in situ macroalgal assemblages was minimally affected by natural temperature variation, possibly through photo-acclimation or temperature acclimation responses, but respiration rates and compensating irradiance were negatively affected. However, laboratory experiments testing the impacts of rising temperature on several photosynthetic parameters showed a decline in NPP, increasing respiration rates and increasing compensating irradiance. The respiration Q10 of laboratory assemblages (the difference in metabolic rates over 10°C averaged 2.9 compared to a Q10 of 2 often seen in other autotrophs. However, gross primary productivity (GPP Q10 averaged 2, indicating that respiration was more severely affected by rising temperature. Furthermore, combined high irradiance and high temperature caused photoinhibition in the laboratory, and resulted in 50% lower NPP at high irradiance. Our study shows that communities may be more severely affected by rising global temperatures than would be expected by responses of individual species. In particular, enhanced respiration rates and rising compensation points have the potential to greatly affect the carbon balance of macroalgal assemblages through declines in

  17. Ionic strength effect on molecular structure of hyaluronic acid investigated by flow field-flow fractionation and multiangle light scattering.

    Kim, Bitnara; Woo, Sohee; Park, Young-Soo; Hwang, Euijin; Moon, Myeong Hee


    This study describes the effect of ionic strength on the molecular structure of hyaluronic acid (HA) in an aqueous solution using flow field-flow fractionation and multiangle light scattering (FlFFF-MALS). Sodium salts of HA (NaHA) raw materials (∼2 × 10(6) Da) dispersed in different concentrations of NaCl prepared by repeated dilution/ultrafiltration procedures were examined in order to study conformational changes in terms of the relationship between the radius of gyration and molecular weight (MW) and molecular weight distribution (MWD) of NaHA in solution. This was achieved by varying the ionic strength of the carrier solution used in a frit-inlet asymmetrical FlFFF (FIAF4) channel. Experiments showed that the average MW of NaHA increased as the ionic strength of the NaHA solution decreased due to enhanced entanglement or aggregation of HA molecules. Relatively large molecules (greater than ∼5 MDa) did not show a large increase in RMS radius value as the NaCl concentration decreased. Conversely, smaller species showed larger changes, suggesting molecular expansion at lower ionic strengths. When the ionic strength of the FlFFF carrier solution was decreased, the HA species in a salt-rich solution (0.2 M NaCl) underwent rapid molecular aggregation during FlFFF separation. However, when salt-depleted HA samples (I = 4.66∼0.38 mM) were analyzed with FFF carrier solutions of a high ionic strength, the changes in both molecular structure and size were somewhat reversible, although there was a delay in correction of the molecular structure.

  18. Quantitative visualization of coherent flow structures in alluvial channels using multibeam echo-sounding

    Parsons, D. R.; Simmons, S.; Best, J.


    Multibeam Echo-Sounder systems have developed rapidly over recent decades and are routinely deployed to provide high-resolution bathymetric details in range of aquatic environments. Modern data handling and storage technologies now facilitate the logging of the raw acoustic back-scatter information that was previously discarded by these systems. This paper describes methodologies that exploit this logging capability to quantify the concentration and dynamics of suspended sediment within the water column and presents a novel method that also allows for quantification of 2D flow velocities. This development provides a multi-purpose tool for the holistic surveying of the process linkages between flow, sediment transport and bed morphology. The application of this new technique is illustrated with reference to flow over alluvial sand dunes, which allows, for the first time in a field study, quantitative visualization of larg-scale, whole flow field, turbulent coherent flow structures, associated with the dune leeside, that are responsible for suspending bed sediment. This methodology holds great potential for use in a wide range of aqueous geophysical flows. CFS captured by MBES in the lee of an alluvial dune. Contours of suspended sediment concentration and superimposed 2D flow velocity vectors

  19. Renormalization-group flow of the effective action of cosmological large-scale structures

    Floerchinger, Stefan


    Following an approach of Matarrese and Pietroni, we derive the functional renormalization group (RG) flow of the effective action of cosmological large-scale structures. Perturbative solutions of this RG flow equation are shown to be consistent with standard cosmological perturbation theory. Non-perturbative approximate solutions can be obtained by truncating the a priori infinite set of possible effective actions to a finite subspace. Using for the truncated effective action a form dictated by dissipative fluid dynamics, we derive RG flow equations for the scale dependence of the effective viscosity and sound velocity of non-interacting dark matter, and we solve them numerically. Physically, the effective viscosity and sound velocity account for the interactions of long-wavelength fluctuations with the spectrum of smaller-scale perturbations. We find that the RG flow exhibits an attractor behaviour in the IR that significantly reduces the dependence of the effective viscosity and sound velocity on the input ...

  20. Flow environment and matrix structure interact to determine spatial competition in Pseudomonas aeruginosa biofilms.

    Nadell, Carey D; Ricaurte, Deirdre; Yan, Jing; Drescher, Knut; Bassler, Bonnie L


    Bacteria often live in biofilms, which are microbial communities surrounded by a secreted extracellular matrix. Here, we demonstrate that hydrodynamic flow and matrix organization interact to shape competitive dynamics in Pseudomonas aeruginosa biofilms. Irrespective of initial frequency, in competition with matrix mutants, wild-type cells always increase in relative abundance in planar microfluidic devices under simple flow regimes. By contrast, in microenvironments with complex, irregular flow profiles - which are common in natural environments - wild-type matrix-producing and isogenic non-producing strains can coexist. This result stems from local obstruction of flow by wild-type matrix producers, which generates regions of near-zero shear that allow matrix mutants to locally accumulate. Our findings connect the evolutionary stability of matrix production with the hydrodynamics and spatial structure of the surrounding environment, providing a potential explanation for the variation in biofilm matrix secretion observed among bacteria in natural environments.

  1. Harbingers and latecomers - The order of appearance of exact coherent structures in plane Poiseuille flow

    Zammert, Stefan


    The transition to turbulence in plane Poiseuille flow (PPF) is connected with the presence of exact coherent structures. In contrast to other shear flows, PPF has a number of different coherent states that are relevant for the transition. We here discuss the different states, compare the critical Reynolds numbers and optimal wavelengths for their appearance, and explore the differences between flows operating at constant mass flux or at constant pressure drop. The Reynolds numbers quoted here are based on the mean flow velocity and refer to constant mass flux, the ones for constant pressure drop are always higher. The Tollmien-Schlichting waves bifurcate subcritically from the laminar profile at $Re=5772$ and reach down to $Re=2609$ (at a different optimal wave length). Their localized counter part bifurcates at the even lower value $Re=2334$. Three dimensional exact solutions appear at much lower Reynolds numbers. We describe one exact solutions that is spanwise localized and has a critical Reynolds number o...

  2. Numerical study of roll motion of a 2-D floating structure in viscous flow



    In the present study, an open source CFD tool, OpenFOAM has been extended and applied to investigate roll motion of a 2-D rectangular barge induced by nonlinear regular waves in viscous flow. Comparisons of the present OpenFOAM results with published potential-flow solutions and experimental data have indicated that the newly extended OpenFOAM model is very capable of accurate modelling of wave interaction with freely rolling structures. The wave-induced roll motions, hydrodynamic forces on the barge, velocities and vorticity fields in the vicinity of the structure in the presence of waves have been investigated to reveal the real physics involved in the wave induced roll motion of a 2-D floating structure. Parametric analysis has been carried out to examine the effect of structure dimension and body draft on the roll motion.

  3. The coupling of cerebral blood flow and oxygen metabolism with brain activation is similar for simple and complex stimuli in human primary visual cortex.

    Griffeth, Valerie E M; Simon, Aaron B; Buxton, Richard B


    Quantitative functional MRI (fMRI) experiments to measure blood flow and oxygen metabolism coupling in the brain typically rely on simple repetitive stimuli. Here we compared such stimuli with a more naturalistic stimulus. Previous work on the primary visual cortex showed that direct attentional modulation evokes a blood flow (CBF) response with a relatively large oxygen metabolism (CMRO2) response in comparison to an unattended stimulus, which evokes a much smaller metabolic response relative to the flow response. We hypothesized that a similar effect would be associated with a more engaging stimulus, and tested this by measuring the primary human visual cortex response to two contrast levels of a radial flickering checkerboard in comparison to the response to free viewing of brief movie clips. We did not find a significant difference in the blood flow-metabolism coupling (n=%ΔCBF/%ΔCMRO2) between the movie stimulus and the flickering checkerboards employing two different analysis methods: a standard analysis using the Davis model and a new analysis using a heuristic model dependent only on measured quantities. This finding suggests that in the primary visual cortex a naturalistic stimulus (in comparison to a simple repetitive stimulus) is either not sufficient to provoke a change in flow-metabolism coupling by attentional modulation as hypothesized, that the experimental design disrupted the cognitive processes underlying the response to a more natural stimulus, or that the technique used is not sensitive enough to detect a small difference. Copyright © 2014 Elsevier Inc. All rights reserved.

  4. Control of 2D Flexible Structures by Confinement of Vibrations and Regulation of Their Energy Flow

    Fakhreddine Landolsi


    Full Text Available In this paper, we investigate the control of 2D flexible structures by vibration confinement and the regulation of their energy flow along prespecified spatial paths. A discretized-model-based feedback strategy, aiming at confining and suppressing simultaneously the vibration, is proposed. It is assumed that the structure consists of parts that are sensitive to vibrations. The control design introduces a new pseudo-modal matrix derived from the computed eigenvectors of the discretized model. Simulations are presented to show the efficacy of the proposed control law. A parametric study is carried out to examine the effects of the different control parameters on the simultaneous confinement and suppression of vibrations. In addition, we conducted a set of simulations to investigate the flow control of vibrational energy during the confinement-suppression process. We found that the energy flow can be regulated via a set of control parameters for different confinement configurations.

  5. Dynamics of zonal flow-like structures in the edge of the TJ-II stellarator

    Alonso, J A; Arévalo, J; Hidalgo, C; Pedrosa, M A; Van Milligen, B Ph; Carralero, D


    The dynamics of fluctuating electric field structures in the edge of the TJ-II stellarator, that display zonal flow-like traits, is studied. These structures have been shown to be global and affect particle transport dynamically [J.A. Alonso et al., Nucl. Fus. 52 063010 (2012)]. In this article we discuss possible drive (Reynolds stress) and damping (Neoclassical viscosity, geodesic transfer) mechanisms for the associated ExB velocity. We show that: (a) while the observed turbulence-driven forces can provide the necessary perpendicular acceleration, a causal relation could not be firmly established, possibly because of the locality of the Reynolds stress measurements, (b) the calculated neoclassical viscosity and damping times are comparable to the observed zonal flow relaxation times, and (c) although an accompanying density modulation is observed to be associated to the zonal flow, it is not consistent with the excitation of pressure side-bands, like those present in geodesic acoustic oscillations, caused b...

  6. Advances in Computational Fluid-Structure Interaction and Flow Simulation Conference

    Takizawa, Kenji


    This contributed volume celebrates the work of Tayfun E. Tezduyar on the occasion of his 60th birthday. The articles it contains were born out of the Advances in Computational Fluid-Structure Interaction and Flow Simulation (AFSI 2014) conference, also dedicated to Prof. Tezduyar and held at Waseda University in Tokyo, Japan on March 19-21, 2014. The contributing authors represent a group of international experts in the field who discuss recent trends and new directions in computational fluid dynamics (CFD) and fluid-structure interaction (FSI). Organized into seven distinct parts arranged by thematic topics, the papers included cover basic methods and applications of CFD, flows with moving boundaries and interfaces, phase-field modeling, computer science and high-performance computing (HPC) aspects of flow simulation, mathematical methods, biomedical applications, and FSI. Researchers, practitioners, and advanced graduate students working on CFD, FSI, and related topics will find this collection to be a defi...

  7. Localised structures in 2D Kolmogorov flow in large domains: Kinks, Snakes and 'Kolmotons'

    Lucas, Dan


    Kolmogorov flow in two dimensions - the 2D Navier-Stokes equations with a sinusoidal body force - is considered over extended periodic domains to reveal localised spatiotemporal complexity. The flow response mimicks the forcing at small forcing amplitudes but beyond a critical value, the vorticity of the flow localises into `kink' structures. These kinks act as building blocks for multiple localised attractors which emerge as the forcing further intensifies. Most notable of these is a temporally-periodic state which consists of two intertwined and wiggling kinks (resembling a snake) bordered by two steady chaperoning kinks. As the forcing is increased, this `snake' experiences a period doubling cascade to spatially-localised chaos before becoming a localised chaotic repeller through a boundary crisis. Further interesting dynamics arise when these kink and snake structures are confronted with each other. The most eye-catching example of this is the `particle-like' interaction of propagating kinks (christened `...

  8. Experimental Investigation of the Unsteady Flow Structures of Two Interacting Pitching Wings

    Kurt, Melike; Moored, Keith


    Birds, insects and fish propel themselves with unsteady motions of their wings and fins. Many of these animals are also found to fly or swim in three-dimensional flocks and schools. Numerous studies have explored the three-dimensional steady flow interactions and the two-dimensional unsteady flow interactions in collectives. Yet, the characterization of the three-dimensional unsteady interactions remains relatively unexplored. This study aims to characterize the flow structures and interactions between two sinusoidally pitching finite-span wings. The arrangement of the wings varies from a tandem to a bi-plane configuration. The vortex structures for these various arrangements are quantified by using particle image velocimetry. The vortex-wing interactions are also characterized as the synchrony between the wings is modified.

  9. On the structural features of fiber suspensions in converging channel flow

    林建忠; 张凌新


    The structural features of fiber suspensions are dependent on the fiber alignment in the flows. In this work the orientation distribution function and orientation tensors for semi-concentrated fiber suspensions in converging channel flow were calculated, and the evolutions of the fiber alignment and the bulk effective viscosity were analyzed. The results showed that the bulk stress and the effective viscosity were functions of the rate-of-strain tensor and the fiber orientation state; and that the fiber suspensions evolved to steady alignment and tended to concentrate to some preferred directions close to but not same as the directions of local streamlines. The bulk effective viscosity depended on the product of Reynolds number and time. The decrease of effective viscosity near the boundary benefited the increase of the rate of flow. Finally when the fiber alignment went into steady state, the structural features of fiber suspensions were not dependent on the Reynolds number but on the converging channel angle.

  10. Pre-Spud Mud Loss Flow Rate in Steeply Folded Structures

    Wang Zhiyuan


    Full Text Available In this paper, a new method that predicts the pre-spud mud loss flow rate in formations with tectonic fractures of steeply folded structures is proposed. The new method is based on finite element analysis of the palaeo-tectonic and current tectonic stress field and fracture distribution. The steps of the method are as follows. First, palaeo-tectonic stress distribution is simulated through finite element analysis. The tectonic fracture distribution of the region is obtained by combining rock failure criteria with palaeo-tectonic stress distribution. Afterward, the tectonic fracture density, aperture, porosity and permeability are calculated by studying the rebuilding process of current stress to the fracture parameters. Finally, the mud loss flow rate is calculated according to fracture parameters and the basic data of a given well. The new method enables the prediction of the mud loss flow rate before drilling steeply folded structures.

  11. A MEMS-based Air Flow Sensor with a Free-standing Micro-cantilever Structure

    Che-Ming Chiang


    Full Text Available This paper presents a micro-scale air flow sensor based on a free-standingcantilever structure. In the fabrication process, MEMS techniques are used to deposit asilicon nitride layer on a silicon wafer. A platinum layer is deposited on the silicon nitridelayer to form a piezoresistor, and the resulting structure is then etched to create afreestanding micro-cantilever. When an air flow passes over the surface of the cantileverbeam, the beam deflects in the downward direction, resulting in a small variation in theresistance of the piezoelectric layer. The air flow velocity is determined by measuring thechange in resistance using an external LCR meter. The experimental results indicate that theflow sensor has a high sensitivity (0.0284 ω/ms-1, a high velocity measurement limit (45ms-1 and a rapid response time (0.53 s.

  12. Vertical flow in the Thermoelectric Liquid Metal Plasma Facing Structures (TELS) facility at Illinois

    Xu, W. [Center for Plasma-Material Interaction, Dept. Nuclear, Plasma, and Radiological Engineering, University of Illinois at Urbana-Champaign, Urbana (United States); Fiflis, P., E-mail: [Center for Plasma-Material Interaction, Dept. Nuclear, Plasma, and Radiological Engineering, University of Illinois at Urbana-Champaign, Urbana (United States); Szott, M.; Kalathiparambil, K.; Jung, S.; Christenson, M.; Haehnlein, I.; Kapat, A. [Center for Plasma-Material Interaction, Dept. Nuclear, Plasma, and Radiological Engineering, University of Illinois at Urbana-Champaign, Urbana (United States); Andruczyk, D. [Center for Plasma-Material Interaction, Dept. Nuclear, Plasma, and Radiological Engineering, University of Illinois at Urbana-Champaign, Urbana (United States); PPPL (United States); Curreli, D.; Ruzic, D.N. [Center for Plasma-Material Interaction, Dept. Nuclear, Plasma, and Radiological Engineering, University of Illinois at Urbana-Champaign, Urbana (United States)


    Flowing liquid metal PFCs may offer a solution to the issues faced by solid divertor materials in tokamak plasmas. The Liquid–Metal Infused Trenches (LiMIT) concept of Illinois Ruzic et al. (2011) is a liquid metal plasma facing structure which employs thermoelectric magnetohydrodynamic (TEMHD) effects to self-propel lithium through a series of trenches. The combination of an incident heat flux and a magnetic field provide the driving mechanism. Tests have yielded experimental lithium velocities under different magnetic fields, which agree well with theoretical predictions Xu et al. (2013). The thermoelectric force is expected to overcome gravity and be able to drive lithium flow along an arbitrary direction and the strong surface tension of liquid lithium is believed to maintain the surface when Li flows in open trenches. This paper discusses the behavior of the LiMIT structure when inclined to an arbitrary angle with respect to the horizontal.

  13. Fluid Flow through Porous Sandstone with Overprinting and Intersecting Geological Structures of Various Types

    Zhou, X.; Karimi-Fard, M.; Durlofsky, L.; Aydin, A.


    Impact of a wide variety of structural heterogeneities on fluid flow in an aeolian sandstone in the Valley of Fire State Park (NV), such as (1) dilatant fractures (joints), (2) shear fractures (faults), and (3) contraction/compaction structures (compaction bands), are considered. Each type of these structures has its own geometry, spacing, distribution, connectivity, and hydraulic properties, which either enhance or impede subsurface fluid flow. Permeability of these structures may, on average, be a few orders of magnitude higher or lower than those of the corresponding matrix rocks. In recent years, the influence of a single type of these heterogeneities on fluid flow has been studied individually, such as joints, compaction bands or faults. However, as different types of geological structures are commonly present together in the same rock volume, their combined effect requires a more detailed assessment. In this study, fluid flow simulations are performed using a special finite-volume discretization technique that was developed by Karimi-Fard et al. (2004; 2006). Using this approach, thin features such as fractures and compaction bands are represented as linear elements in unstructured 2D models and as planar elements in 3D models, which significantly reduces the total number of cells and simplifies grid generation. The cell geometric information and the cell-to-cell transmissibility obtained from this discretization technique are input to Stanford’s General Purpose Research Simulator (GPRS) for fluid flow simulation. To account for the effects of the various geological structures on subsurface flow, we perform permeability upscaling over regions corresponding to large-scale simulation grid blocks in order to obtain equivalent permeability components in two principal directions. We will focus on the following problems: (1) compaction bands of multisets; (2) compartmentalization of compaction bands of high-angle, low-angle and horizontal; (3) joints overprinting

  14. Application of stereology for two-phase flow structure validation in fluidized bed reactors

    Anweiler Stanisław


    Full Text Available Paper describes a novel method for two-phase gas-solid flow structure validation in fluidized bed reactors. Investigation is based on application of stereology techniques. This is an innovative approach in the field of fluidization phenomena research. Study is focused on the analysis of flow structure images, obtained with high-speed visualization of the fluidization process. Fluidization is conducted in transparent narrow channel, where plastic balls are fluidized by air. Applied stereological analysis is grounded on the linear method and on the method of random and directed secants. This enables 2-dimensional image measurement and 3-dimensional stereological extrapolation. The major result is that for each two-phase gas-solid flow structure a set of stereological parameters exists. This enables quantification of the process. It has been found that the observation of inter-relation of all stereological parameters, during the changing of the flow structure, can be used for system control. The basic conclusion is that knowledge about the character of the changes may be used for constant process adjustment for various two phase systems such as gas-solid or gas-liquid.

  15. Three-dimensional flow structures and unsteady forces on pitching and surging revolving flat plates

    Percin, M.; Van Oudheusden, B.W.


    Tomographic particle image velocimetry was used to explore the evolution of three-dimensional flow structures of revolving low-aspect-ratio flat plates in combination with force measurements at a Reynolds number of 10,000. Two motion kinematics are compared that result in the same terminal condition

  16. On the origin of heterogeneous structure in dense gas-solid flows

    Li, J.; Kuipers, J.A.M.


    The formation and evolution of flow structures in dense gas-fluidized beds with ideal collisional particles (elastic and frictionless) are investigated numerically by employing the discrete particle method, with special focus on the effect of gas¿particle interaction. It is clarified that

  17. Fundamental interactions of vortical structures with boundary layers in two-dimensional flows

    Coutsias, E.A.; Lynov, Jens-Peter


    in the vorticity-stream function representation for bounded geometries. Fundamental processes connected to vorticity detachment from the boundary layers caused by the proximity of vortical structures are described. These processes include enstrophy enhancement of the main flow during bursting events, and pinning...

  18. [Correlation of substrate structure and hydraulic characteristics in subsurface flow constructed wetlands].

    Bai, Shao-Yuan; Song, Zhi-Xin; Ding, Yan-Li; You, Shao-Hong; He, Shan


    The correlation of substrate structure and hydraulic characteristics was studied by numerical simulation combined with experimental method. The numerical simulation results showed that the permeability coefficient of matrix had a great influence on hydraulic efficiency in subsurface flow constructed wetlands. The filler with a high permeability coefficient had a worse flow field distribution in the constructed wetland with single layer structure. The layered substrate structure with the filler permeability coefficient increased from surface to bottom could avoid the short-circuited flow and dead-zones, and thus, increased the hydraulic efficiency. Two parallel pilot-scale constructed wetlands were built according to the numerical simulation results, and tracer experiments were conducted to validate the simulation results. The tracer experiment result showed that hydraulic characteristics in the layered constructed wetland were obviously better than that in the single layer system, and the substrate effective utilization rates were 0.87 and 0.49, respectively. It was appeared that numerical simulation would be favorable for substrate structure optimization in subsurface flow constructed wetlands.

  19. Simulant-material experimental investigation of flow dynamics in the CRBR Upper-Core Structure

    Wilhelm, D.; Starkovich, V.S.; Chapyak, E.J.


    The results of a simulant-material experimental investigation of flow dynamics in the Clinch River Breeder Reactor (CRBR) Upper Core Structure are described. The methodology used to design the experimental apparatus and select test conditions is detailed. Numerous comparisons between experimental data and SIMMER-II Code calculations are presented with both advantages and limitations of the SIMMER modeling features identified.

  20. Three-dimensional flow structures and unsteady forces on pitching and surging revolving flat plates

    Percin, M.; Van Oudheusden, B.W.


    Tomographic particle image velocimetry was used to explore the evolution of three-dimensional flow structures of revolving low-aspect-ratio flat plates in combination with force measurements at a Reynolds number of 10,000. Two motion kinematics are compared that result in the same terminal condition

  1. On the Orientation of Turbulent Structures in Stably Stratified Shear Flows

    Jacobitz, Frank; Moreau, Adam; Aguirre, Joylene


    The orientation of turbulent structures in stably stratified shear flows are investigated using the results of a series of direct numerical simulations. The Richardson number is varied from Ri = 0 , corresponding to unstratified shear flow, to Ri = 1 , corresponding to strongly stratified shear flow. The evolution of the turbulent kinetic energy changes from growth for small Richardson numbers to decay for strong stratification. The orientation of turbulent structures in the flows is determined by the three-dimensional two-point autocorrelation coefficient of velocity magnitude, vorticity magnitude, and fluctuating density. An ellipsoid is fitted to the surface given by a constant autocorrelation coefficient value and the major and minor axes are used to determine the inclination angle of turbulent structures in the plane of shear. The inclination angle is observed to be fairly unaffected by the choice of the autocorrelation coefficient value. In was found that the inclination angle decreases with increasing Richardson number. The structure of the turbulent motion, as characterized by the inclination angle, is therefore directly related to the eventual evolution of the turbulence, as described by the growth or decay rate of the turbulent kinetic energy.

  2. Structural and functional brain changes in early- and mid-stage primary open-angle glaucoma using voxel-based morphometry and functional magnetic resonance imaging.

    Jiang, Ming-Ming; Zhou, Qing; Liu, Xiao-Yong; Shi, Chang-Zheng; Chen, Jian; Huang, Xiang-He


    To investigate structural and functional brain changes in patients with primary open-angle glaucoma (POAG) by using voxel-based morphometry based on diffeomorphic anatomical registration through exponentiated Lie algebra (VBM-DARTEL) and blood oxygenation level dependent functional magnetic resonance imaging (BOLD-fMRI), respectively.Thirteen patients diagnosed with POAG and 13 age- and sex-matched healthy controls were enrolled in the study. For each participant, high-resolution structural brain imaging and blood flow imaging were acquired on a 3.0-Tesla magnetic resonance imaging (MRI) scanner. Structural and functional changes between the POAG and control groups were analyzed. An analysis was carried out to identify correlations between structural and functional changes acquired in the previous analysis and the retinal nerve fiber layer (RNFL).Patients in the POAG group showed a significant (P < 0.001) volume increase in the midbrain, left brainstem, frontal gyrus, cerebellar vermis, left inferior parietal lobule, caudate nucleus, thalamus, precuneus, and Brodmann areas 7, 18, and 46. Moreover, significant (P < 0.001) BOLD signal changes were observed in the right supramarginal gyrus, frontal gyrus, superior frontal gyrus, left inferior parietal lobule, left cuneus, and left midcingulate area; many of these regions had high correlations with the RNFL.Patients with POAG undergo widespread and complex changes in cortical brain structure and blood flow. ( number: NCT02570867).

  3. The primary structure of the hemoglobin of Malayan sun bear (Helarctos malayanus, Carnivora) and structural comparison to other hemoglobin sequences.

    Hofmann, O; Braunitzer, G; Göltenboth, R


    The complete primary structure of the alpha- and beta-chains of the hemoglobin of Malayan Sun Bear (Helarctos malayanus) is presented. After cleavage of the heme-protein link and chain separation by RP-HPLC, amino-acid sequences were determined by Edman degradation in liquid- and gas-phase sequenators. An interesting result of this work is the demonstration that the hemoglobin of Malayan Sun Bear is identical to the hemoglobins of Polar Bear (Ursus maritimus) and Asiatic Black Bear (Ursus tibetanus). The paper gives an updated table of identical hemoglobin chains from different species. This paper may be considered as a compilation of work on the genetic relationship of Pandas.

  4. Structure and work process in primary care and hospitalizations for sensitive conditions.

    Araujo, Waleska Regina Machado; Queiroz, Rejane Christine de Sousa; Rocha, Thiago Augusto Hernandes; Silva, Núbia Cristina da; Thumé, Elaine; Tomasi, Elaine; Facchini, Luiz Augusto; Thomaz, Erika Barbara Abreu Fonseca


    The objective of this study is to investigate whether the characteristics of the structure of primary health units and the work process of primary care teams are associated with the number of hospitalizations for primary care sensitive conditions. In this ecological study, we have analyzed data of Brazilian municipalities related to sociodemographic characteristics, coverage of care programs, structure of primary health units, and work process of primary care teams. We have obtained the data from the first cycle of the Brazilian Program for Improving Access and Quality of the Primary Care, of the Department of Information Technology of the Brazilian Unified Health System, the Brazilian Institute of Geography and Statistics, and the United Nations Development Programme. The associations have been estimated using negative binomial regression coefficients (β) and respective 95% confidence intervals, with a hierarchical approach in three levels (alpha = 5%). In the adjusted analysis for the outcome in 2013, in the distal level, the coverage of the Bolsa Família Program (β = -0.001) and private insurance (β = -0.01) had a negative association, and the human development index (β = 1.13), the proportion of older adults (β = 0.05) and children under the age of five (β = 0.05), and the coverage of the Community Health Agent Strategy (β = 0.002) showed positive association with hospitalizations for primary care sensitive conditions. In the intermediate level, minimum hours (β = -0.14) and availability of vaccines (β = -0.16) showed a negative association, and availability of medications showed a positive association (β = 0.16). In the proximal level, only the variable of matrix support (β = 0.10) showed a positive association. The variables in the adjusted analysis of the number of hospitalizations for primary care sensitive conditions in 2014 presented the same association as in 2013. The characteristics of the structure of primary health units and the work

  5. Coherent Flow Structures and Suspension Events over Low-angle Dunes: Fraser River, Canada

    Bradley, R. W.; Venditti, J. G.; Kostaschuk, R. A.; Hendershot, M. L.; Allison, M. A.; Church, M. A.


    Increasing observations show that dunes with low-angle lee-sides (MBES) while an acoustic Doppler current profiler (aDcp) simultaneously provided flow and suspended sediment measurements over a range of flows through tidal cycles. At high tide, river flow nearly ceases and a salt wedge enters the channel, forcing plumes of salt water towards the surface into the downstream moving fresh water above as the wedge moves upstream over the dunes. The salt wedge persists in the channel causing stratification in water column and one-sided instabilities along the saline-fresh water interface until the late in the falling tide. At low tide, mean velocities peak and force the saline water out of the channel. Flow over the low-angle dunes displays topographically induced flow patterns similar to previously observed over high-angle dunes, but permanent flow separation is notably absent. Sediment-laden kolks emerge as important suspended sediment transport agents during low tide but become more coherent, yet less frequent, structures as the tide begins to rise. Kolks appear to form downstream of dune crests along the shear layer that is likely formed by intermittent flow separation. Kolks also form at the reattachment point and grow over the stoss slope of the dunes. This is consistent with the generation of hairpin vortices formed near the bed that lift into the flow and grow to the surface through an 'autogeneration' mechanism. Persistent downwelling and periodic sweeps at dune crests provide a mechanism for sediment erosion and entrainment while periodic ejection motions or kolks in a zone of persistent upwelling at the lower stoss provide a mechanism sediment suspension. Kolks are estimated to move ~70% of the total sediment in the flow above dunes when they are present in the water column.

  6. Primary structure and solution conditions determine conformational ensemble properties of intrinsically disordered proteins

    Mao, Hsuan-Han Alberto

    Intrinsically disordered proteins (IDPs) are a class of proteins that do not exhibit well-defined three-dimensional structures. The absence of structure is intrinsic to their amino acid sequences, which are characterized by low hydrophobicity and high net charge per residue compared to folded proteins. Contradicting the classic structure-function paradigm, IDPs are capable of interacting with high specificity and affinity, often acquiring order in complex with protein and nucleic acid binding partners. This phenomenon is evident during cellular activities involving IDPs, which include transcriptional and translational regulation, cell cycle control, signal transduction, molecular assembly, and molecular recognition. Although approximately 30% of eukaryotic proteomes are intrinsically disordered, the nature of IDP conformational ensembles remains unclear. In this dissertation, we describe relationships connecting characteristics of IDP conformational ensembles to their primary structures and solution conditions. Using molecular simulations and fluorescence experiments on a set of base-rich IDPs, we find that net charge per residue segregates conformational ensembles along a globule-to-coil transition. Speculatively generalizing this result, we propose a phase diagram that predicts an IDP's average size and shape based on sequence composition and use it to generate hypotheses for a broad set of intrinsically disordered regions (IDRs). Simulations reveal that acid-rich IDRs, unlike their oppositely charged base-rich counterparts, exhibit disordered globular ensembles despite intra-chain repulsive electrostatic interactions. This apparent asymmetry is sensitive to simulation parameters for representing alkali and halide salt ions, suggesting that solution conditions modulate IDP conformational ensembles. We refine the ion parameters using a calibration procedure that relies exclusively on crystal lattice properties. Simulations with these parameters recover swollen

  7. Flow structures and heat transfer on dimples in a staggered arrangement

    Turnow, Johann, E-mail: [Institute of Modeling and Simulation, University of Rostock, Albert-Einstein-Str. 2, 18059 Rostock (Germany); Kornev, Nikolai [Institute of Modeling and Simulation, University of Rostock, Albert-Einstein-Str. 2, 18059 Rostock (Germany); Zhdanov, Valery; Hassel, Egon [Institute of Technical Thermodynamics, University of Rostock, Albert-Einstein-Str. 2, 18059 Rostock (Germany)


    Highlights: Black-Right-Pointing-Pointer Investigations have been performed to analyze turbulent flow over dimpled surfaces. Black-Right-Pointing-Pointer Vortex structures and integral values are determined in the turbulent flow regime. Black-Right-Pointing-Pointer POD method is applied on pressure and velocity fields obtained from LES. Black-Right-Pointing-Pointer An optimal dimple depth was found in respect to the thermo-hydraulic performance. - Abstract: Vortex structures and heat transfer enhancement mechanism of turbulent flow over a staggered array of dimples in a narrow channel have been investigated using Large Eddy Simulation (LES), Laser Doppler Velocimetry (LDV) and pressure measurements for Reynolds numbers Re{sub H} = 6521 and Re{sub H} = 13,042. The flow and temperature fields are calculated by LES using dynamic mixed model applied both for the velocity and temperature. Simulations have been validated with experimental data obtained for smooth and dimpled channels and empiric correlations. The flow structures determined by LES inside the dimple are chaotic and consist of small eddies with a broad range of scales where coherent structures are hardly to detect. Proper Orthogonal Decomposition (POD) method is applied on resolved LES fields of pressure and velocity to identify spatial-temporal structures hidden in the random fluctuations. For both Reynolds numbers it was found that the dimple package with a depth h to diameter D ratio of h/D = 0.26 provides the maximum thermo-hydraulic performance. The heat transfer rate could be enhanced up to 201% compared to a smooth channel.

  8. Emerging organic contaminant removal depending on primary treatment and operational strategy in horizontal subsurface flow constructed wetlands: influence of redox.

    Avila, Cristina; Reyes, Carolina; Bayona, Josep María; García, Joan


    This study aimed at assessing the influence of primary treatment (hydrolytic upflow sludge blanket (HUSB) reactor vs. conventional settling) and operational strategy (alternation of saturated/unsaturated phases vs. permanently saturated) on the removal of various emerging organic contaminants (i.e. ibuprofen, diclofenac, acetaminophen, tonalide, oxybenzone, bisphenol A) in horizontal subsurface flow constructed wetlands. For that purpose, a continuous injection experiment was carried out in an experimental treatment plant for 26 days. The plant had 3 treatment lines: a control line (settler-wetland permanently saturated), a batch line (settler-wetland operated with saturate/unsaturated phases) and an anaerobic line (HUSB reactor-wetland permanently saturated). In each line, wetlands had a surface area of 2.95 m(2), a water depth of 25 cm and a granular medium D(60) = 7.3 mm, and were planted with common reed. During the study period the wetlands were operated at a hydraulic and organic load of 25 mm/d and about 4.7 g BOD/m(2)d, respectively. The injection experiment delivered very robust results that show how the occurrence of higher redox potentials within the wetland bed promotes the elimination of conventional quality parameters as well as emerging microcontaminants. Overall, removal efficiencies were always greater for the batch line than for the control and anaerobic lines, and to this respect statistically significantly differences were found for ibuprofen, diclofenac, oxybenzone and bisphenol A. As an example, ibuprofen, whose major removal mechanism has been reported to be biodegradation under aerobic conditions, showed a higher removal in the batch line (85%) than in the control (63%) and anaerobic (52%) lines. Bisphenol A showed also a great dependence on the redox status of the wetlands, finding an 89% removal rate for the batch line, as opposed to the control and anaerobic lines (79 and 65%, respectively). Furthermore, diclofenac showed a greater

  9. The influence of flow cell geometry related shear stresses on the distribution, structure and susceptibility of Pseudomonas aeruginosa 01 biofilms.

    Salek, M Mehdi; Jones, Steven M; Martinuzzi, Robert J


    The effects of non-uniform hydrodynamic conditions resulting from flow cell geometry (square and rectangular cross-section) on Pseudomonas aeruginosa 01 (PAO1) biofilm formation, location, and structure were investigated for nominally similar flow conditions using a combination of confocal scanning laser microscope (CSLM) and computational fluid dynamics (CFD). The thickness and surface coverage of PAO1 biofilms were observed to vary depending on the location in the flow cell and thus also the local wall shear stress. The biofilm structure in a 5:1 (width to height) aspect ratio rectangular flow cell was observed to consist mainly of a layer of bacterial cells with thicker biofilm formation observed in the flow cell corners. For square cross-section (1:1 aspect ratio) flow cells, generally thicker and more uniform surface coverage biofilms were observed. Mushroom shaped structures with hollow centers and wall breaks, indicative of 'seeding' dispersal structures, were found exclusively in the square cross-section tubes. Exposure of PAO1 biofilms grown in the flow cells to gentamicin revealed a difference in susceptibility. Biofilms grown in the rectangular flow cell overall exhibited a greater susceptibility to gentamicin compared to those grown in square flow cells. However, even within a given flow cell, differences in susceptibility were observed depending on location. This study demonstrates that the spanwise shear stress distribution within the flow cells has an important impact on the location of colonization and structure of the resultant biofilm. These differences in biofilm structure have a significant impact on the susceptibility of the biofilms grown within flow channels. The impact of flow modification due to flow cell geometry should be considered when designing flow cells for laboratory investigation of bacterial biofilms.

  10. A study of the turbulence structures of wall-bounded shear flows

    Chong, M. S.; Soria, J.; Perry, A. E.; Chacin, J.; Na, Y.; Cantwell, B. J.


    This project extends the study of the structure of wall-bounded flows using the topological properties of eddying motions as developed by Chong et al. (1990), Soria et al. (1992, 1994), and as recently extended by Blackburn et al. (1996) and Chacin et al. (1996). In these works, regions of flow which are focal in nature are identified by being enclosed by an isosurface of a positive small value of the discriminant of the velocity gradient tensor. These regions resemble the attached vortex loops suggested first by Theodorsen (1955). Such loops are incorporated in the attached eddy model versions of Perry & Chong (1982), Perry et al. (1986), and Perry & Marusic (1995), which are extensions of a model first formulated by Townsend (1976). The DNS data of wall bounded flows studied here are from the zero pressure gradient flow of Spalart (1988) and the boundary layer with separation and reattachment of Na & Moin (1996). The flow structures are examined from the viewpoint of the attached eddy hypothesis.

  11. Microbridge structures for uniform interval control of flowing droplets in microfluidic networks.

    Lee, Do-Hyun; Lee, Wonhye; Um, Eujin; Park, Je-Kyun


    Precise temporal control of microfluidic droplets such as synchronization and combinatorial pairing of droplets is required to achieve a variety range of chemical and biochemical reactions inside microfluidic networks. Here, we present a facile and robust microfluidic platform enabling uniform interval control of flowing droplets for the precise temporal synchronization and pairing of picoliter droplets with a reagent. By incorporating microbridge structures interconnecting the droplet-carrying channel and the flow control channel, a fluidic pressure drop was derived between the two fluidic channels via the microbridge structures, reordering flowing droplets with a defined uniform interval. Through the adjustment of the control oil flow rate, the droplet intervals were flexibly and precisely adjustable. With this mechanism of droplet spacing, the gelation of the alginate droplets as well as control of the droplet interval was simultaneously achieved by additional control oil flow including calcified oleic acid. In addition, by parallel linking identical microfluidic modules with distinct sample inlet, controlled synchronization and pairing of two distinct droplets were demonstrated. This method is applicable to facilitate and develop many droplet-based microfluidic applications, including biological assay, combinatorial synthesis, and high-throughput screening.

  12. On the correspondence between flow structures and convective heat transfer augmentation for multiple jet impingement

    Terzis, Alexandros


    The correspondence between local fluid flow structures and convective heat transfer is a fundamental aspect that is not yet fully understood for multiple jet impingement. Therefore, flow field and heat transfer experiments are separately performed investigating mutual-jet interactions exposed in a self-gained crossflow. The measurements are taken in two narrow impingement channels with different cross-sectional areas and a single exit design. Hence, a gradually increased crossflow momentum is developed from the spent air of the upstream jets. Particle image velocimetry (PIV) and liquid crystal thermography (LCT) are used in order to investigate the aerothermal characteristics of the channel with high spatial resolution. The PIV measurements are taken at planes normal to the target wall and along the centreline of the jets, providing quantitative flow visualisation of jet and crossflow interactions. Spatially resolved heat transfer coefficient distributions on the target plate are evaluated with transient techniques and a multi-layer of thermochromic liquid crystals. The results are analysed aiming to provide a better understanding about the impact of near-wall flow structures on the convective heat transfer augmentation for these complex flow phenomena.

  13. Structural, electronic and optical properties of well-known primary explosive: Mercury fulminate

    Yedukondalu, N.; Vaitheeswaran, G., E-mail: [Advanced Centre of Research in High Energy Materials (ACRHEM), University of Hyderabad, Prof. C. R. Rao Road, Gachibowli, Hyderabad, Telangana 500046 (India)


    Mercury Fulminate (MF) is one of the well-known primary explosives since 17th century and it has rendered invaluable service over many years. However, the correct molecular and crystal structures are determined recently after 300 years of its discovery. In the present study, we report pressure dependent structural, elastic, electronic and optical properties of MF. Non-local correction methods have been employed to capture the weak van der Waals interactions in layered and molecular energetic MF. Among the non-local correction methods tested, optB88-vdW method works well for the investigated compound. The obtained equilibrium bulk modulus reveals that MF is softer than the well known primary explosives Silver Fulminate (SF), silver azide and lead azide. MF exhibits anisotropic compressibility (b > a > c) under pressure, consequently the corresponding elastic moduli decrease in the following order: C{sub 22} > C{sub 11} > C{sub 33}. The structural and mechanical properties suggest that MF is more sensitive to detonate along c-axis (similar to RDX) due to high compressibility of Hg⋯O non-bonded interactions along that axis. Electronic structure and optical properties were calculated including spin-orbit (SO) interactions using full potential linearized augmented plane wave method within recently developed Tran-Blaha modified Becke-Johnson (TB-mBJ) potential. The calculated TB-mBJ electronic structures of SF and MF show that these compounds are indirect bandgap insulators. Also, SO coupling is found to be more pronounced for 4d and 5d-states of Ag and Hg atoms of SF and MF, respectively. Partial density of states and electron charge density maps were used to describe the nature of chemical bonding. Ag—C bond is more directional than Hg—C bond which makes SF to be more unstable than MF. The effect of SO coupling on optical properties has also been studied and found to be significant for both (SF and MF) of the compounds.

  14. Heat flow distribution and thermal structure of the Nankai subduction zone off the Kii Peninsula

    Hamamoto, Hideki; Yamano, Makoto; Goto, Shusaku; Kinoshita, Masataka; Fujino, Keiko; Wang, Kelin


    Detailed heat flow surveys were carried out in the central part of the Nankai Trough southeast of the Kii Peninsula (off Kumano) for investigation of the thermal structure of the subducting plate interface. At stations in the Kumano Trough (forearc basin) and its vicinity, long-term monitoring of temperature profiles in surface sediments was conducted because bottom water temperature variations (BTV) significantly disturb subbottom sediment temperatures. Heat flow values were successfully determined at seven stations by removing the influence of BTV from temperature records for 300 to 400 days. The surface heat flow data were combined with estimates from depths of methane hydrate bottom simulating reflectors to construct a heat flow profile across the subduction zone. Heat flow decreases from 90-110 mW/m2 on the floor of the Nankai Trough to 50-60 mW/m2 at around 30 km from the deformation front, while it is rather uniform, 40-60 mW/m2, in the Kumano Trough. The values measured on the Nankai Trough floor are concordant with the value estimated from the age of the subducting Philippine Sea plate, about 20 m.y., taking into account the effect of sedimentation. The obtained heat flow profile was used to constrain thermal models of the subduction zone. The subsurface thermal structure was calculated using a two-dimensional, steady state model, in which the frictional heating along the plate interface and the radioactive heat production are treated as unknown parameters. Comparison of the calculated surface heat flow in the Kumano Trough with the observed data indicates that the effective coefficient of friction is small, about 0.1 or less, and thus the shear stress on the plate interface is very low in this subduction zone.

  15. The evolution of viscous flow structures in the esophagus during tracheoesophageal speech

    Erath, Byron; Hemsing, Frank


    A laryngectomy is an invasive surgical procedure whereby the entire larynx is removed, usually as a result of cancer. Removal of the larynx renders conventional voiced speech impossible, with the most common remediation following surgery being tracheoeosphageal (TE) speech. TE speech is produced by inserting a one-way valve to connect the posterior wall of the trachea with the anterior wall of the esophagus. As air is forced up from the lungs it passes through the prosthesis and into the esophagus. The resulting esophageal pressure field incites self-sustained oscillations of the pharyngoesophageal segment (PES), which ultimately produces sound. Unfortunately, the physics of TE speech are not well understood, with up to 50% of individuals unable to produce intelligible sound. This failure can be related to a lack of understanding regarding the esophageal flow field, where all previous scientific investigations have assumed the flow is one-dimensional and steady. An experimental TE speech flow facility was constructed and particle image velocimetry measurements were acquired at the exit of the model prosthesis (entrance of the esophagus). The flow is observed to be highly unsteady, and the formation and propagation of vortical flow structures through the esophageal tract are identified. Observations regarding the influence of the flow dynamics on the esophageal pressure field and its relation to the successful production of TE speech are discussed.

  16. Simulation of the effect of defence structures on granular flows using SPH

    P. Lachamp


    Full Text Available This paper presents the SPH (Smoothed Particles Hydrodynamics numerical method adapted to complex rheology and free surface flow. It has been developed to simulate the local effect of a simple obstacle on a granular flow. We have introduced this specific rheology to the classical formalism of the method and thanks to experimental devices, we were able to validate the results. Two viscosity values have been simultaneously computed to simulate "plugs" and "dead zone" with the same code. First, some experiments have been done on a simple inclined slope to show the accuracy of the numerical results. We have fixed the mass flow rate to see the variations of the flow depth according to the channel slope. Then we put a weir to block the flow and we analysed the dependence between the obstacle height and the length of influence upstream from the obstacle. After having shown that numerical results were consistent, we have studied speed profiles and pressure impact on the structure. Also results with any topography will be presented. This will have a great interest to study real flow over natural topography while using the model for decision help.

  17. Understanding characteristics in multivariate traffic flow time series from complex network structure

    Yan, Ying; Zhang, Shen; Tang, Jinjun; Wang, Xiaofei


    Discovering dynamic characteristics in traffic flow is the significant step to design effective traffic managing and controlling strategy for relieving traffic congestion in urban cities. A new method based on complex network theory is proposed to study multivariate traffic flow time series. The data were collected from loop detectors on freeway during a year. In order to construct complex network from original traffic flow, a weighted Froenius norm is adopt to estimate similarity between multivariate time series, and Principal Component Analysis is implemented to determine the weights. We discuss how to select optimal critical threshold for networks at different hour in term of cumulative probability distribution of degree. Furthermore, two statistical properties of networks: normalized network structure entropy and cumulative probability of degree, are utilized to explore hourly variation in traffic flow. The results demonstrate these two statistical quantities express similar pattern to traffic flow parameters with morning and evening peak hours. Accordingly, we detect three traffic states: trough, peak and transitional hours, according to the correlation between two aforementioned properties. The classifying results of states can actually represent hourly fluctuation in traffic flow by analyzing annual average hourly values of traffic volume, occupancy and speed in corresponding hours.


    Howard, T. K.; Marcum, W. R.; Latimer, G. D.; Weiss, A.; Jones, W. F.; Phillips, A. M.; Woolstenhulme, N.; Holdaway, K.; Campbell, J.


    Four tests characterizing the structural response of the Chopped-Dummy In-Pile tube (CDIPT) experiment design were measured in the Hydro-Mechanical Fuel Test Facility (HMFTF). Four different test configurations were tried. These configurations tested the pressure drop and flow impact of various plate configurations and flow control orifices to be used later at different reactor power levels. Accelerometers were placed on the test vehicle and flow simulation housing. A total of five accelerometers were used with one on the top and bottom of the flow simulator and vehicle, and one on the outside of the flow simulator. Data were collected at a series of flow rates for 5 seconds each at an acquisition rate of 2 kHz for a Nyquist frequency of 1 kHz. The data were then analyzed using a Fast Fourier Transform (FFT) algorithm. The results show very coherent vibrations of the CDIPT experiment on the order of 50 Hz in frequency and 0.01 m/s2 in magnitude. The coherent vibrations, although small in magnitude pose a potential design problem if the frequencies coincide with the natural frequency of the fueled plates or test vehicle. The accelerometer data was integrated and combined to create a 3D trace of the experiment during the test. The merits of this data as well as further anomalies and artifacts are also discussed as well as their relation to the instrumentation and experiment design.

  19. Computational study of liquid-gas cross-flow within structured packing cells

    Lavalle, Gianluca; Lucquiaud, Mathieu; Valluri, Prashant


    Absorption columns used in the carbon capture processes and filled with structured packings are crucial to foster the exchanges and the transfers between the absorber liquid and the flue gas. However, flow reversal can occur under special flow conditions, resulting in a dramatic drop of the technological performances. We investigate numerically the liquid-gas pattern within a cross-flow packing cell. The cell is a complex geometry with two connected channels, where the two phases flow co- or counter-currently. We show that an increase of both the gas speed and the liquid load leads to an increase of the pressure drop. Particular focus is also given to the analysis of flow repartition and flooding delay. We reveal that tilting the unit cell helps to delay the flooding and extends the operational capability. The pressure drop of the cross-flow unit cell is also compared to the Mellapak packing which is widely used in carbon capture applications. Finally, we support this study by performing numerical simulations on simpler geometries by means of a low-dimensional film-gas model, in order to investigate the two-phase dynamics and predict the flooding onset with a low computational cost. The authors gratefully acknowledge EPSRC Grant No. EP/M001482/1.

  20. Measuring In-Plane Micro-Motion of Micro-Structure Using Optical Flow

    JIN Cuiyun; JIN Shijiu; LI Dachao; WANG Jianlin


    Optical flow method is one of the most important methods of analyzing motion images.Optical flow field is used to analyze characteristics of motion objects.According to motion features of micro-electronic mechanical system(MEMS)micro-structure,the optical algorithm based on label field and neighborhood optimization is presented to analyze the in-plane micro-motion of micro-structure.Firstly,high speed motion states for each frequency segment of micro-structure in cyclic motion are frozen based on stroboscopic principle.Thus a series of image sequences,and can obtain reliable and precise optical field and reduce computing time.As micro-resonator of urement precision of the presented algorithm is high,and measurement repeatability reaches 40 am under the same experiment condition.

  1. How best to structure interdisciplinary primary care teams: the study protocol for a systematic review with narrative framework synthesis.

    Wranik, W Dominika; Hayden, Jill A; Price, Sheri; Parker, Robin M N; Haydt, Susan M; Edwards, Jeanette M; Suter, Esther; Katz, Alan; Gambold, Liesl L; Levy, Adrian R


    Western publicly funded health care systems increasingly rely on interdisciplinary teams to support primary care delivery and management of chronic conditions. This knowledge synthesis focuses on what is known in the academic and grey literature about optimal structural characteristics of teams. Its goal is to assess which factors contribute to the effective functioning of interdisciplinary primary care teams and improved health system outcomes, with specific focus on (i) team structure contribution to team process, (ii) team process contribution to primary care goals, and (iii) team structure contribution to primary care goals. The systematic search of academic literature focuses on four chronic conditions and co-morbidities. Within this scope, qualitative and quantitative studies that assess the effects of team characteristics (funding, governance, organization) on care process and patient outcomes will be searched. Electronic databases (Ovid MEDLINE, Embase, CINAHL, PAIS, Web of Science) will be searched systematically. Online web-based searches will be supported by the Grey Matters Tool. Studies will be included, if they report on interdisciplinary primary care in publicly funded Western health systems, and address the relationships between team structure, process, and/or patient outcomes. Studies will be selected in a three-stage screening process (title/abstract/full text) by two independent reviewers in each stage. Study quality will be assessed using the Mixed Methods Assessment Tool. An a priori framework will be applied to data extraction, and a narrative framework approach is used for the synthesis. Using an integrated knowledge translation approach, an electronic decision support tool will be developed for decision makers. It will be searchable along two axes of inquiry: (i) what primary care goals are supported by specific team characteristics and (ii) how should teams be structured to support specific primary care goals? The results of this evidence

  2. Flow Energy Piezoelectric Bimorph Nozzle Harvester

    Sherrit, Stewart (Inventor); Walkemeyer, Phillip E. (Inventor); Hall, Jeffrey L. (Inventor); Lee, Hyeong Jae (Inventor); Colonius, Tim (Inventor); Tosi, Phillipe (Inventor); Kim, Namhyo (Inventor); Sun, Kai (Inventor); Corbett, Thomas Gary (Inventor); Arrazola, Alvaro Jose (Inventor)


    A flow energy harvesting device having a harvester pipe includes a flow inlet that receives flow from a primary pipe, a flow outlet that returns the flow into the primary pipe, and a flow diverter within the harvester pipe having an inlet section coupled to the flow inlet, a flow constriction section coupled to the inlet section and positioned at a midpoint of the harvester pipe and having a spline shape with a substantially reduced flow opening size at a constriction point along the spline shape, and an outlet section coupled to the constriction section. The harvester pipe may further include a piezoelectric structure extending from the inlet section through the constriction section and point such that the fluid flow past the constriction point results in oscillatory pressure amplitude inducing vibrations in the piezoelectric structure sufficient to cause a direct piezoelectric effect and to generate electrical power for harvesting.

  3. Mushroom-Shaped Structures as Tracers of Buoyant Flow in the Galactic Disk

    D'Avillez, M A; Avillez, Miguel A. de; Low, Mordecai-Mark Mac


    Recent HI emission observations of the Southern Galactic hemisphere have revealed a mushroom-like structure extending from z=-70 to -450 pc, composed of a stem and a cap. Similar structures occur in three-dimensional simulations of a dynamic galactic disk driven by isolated and clustered supernovae. Using these simulations, we show that hot gas in the Galactic disk that is not evacuated through chimneys expands into the cooler gas of the thick disk, forming mushroom-shaped structures. This new class of objects traces buoyant flow of hot gas into the thick disk.

  4. Structural Changes of International Trade Flows under the Impact of Globalization

    Anca Dachin


    Full Text Available Structural changes of international trade flows indicate modifications in competitiveness of countries, in terms of production, technological upgrading and exports under the pressure of globalization. The paper aims to point out sources of competitive advantages especially in manufacturing exports of different groups of countries. The focus is on the shifts in the structure of manufacturing in the European Union and their effects on international rankings in export performances. An important issue refers to the opportunities given by the enlargement of the European Union and their impact on EU trade structures.

  5. Altered structural and functional connectivity between the bilateral primary motor cortex in unilateral subcortical stroke

    Zhang, Yong; Li, Kuang-Shi; Ning, Yan-Zhe; Fu, Cai-Hong; Liu, Hong-Wei; Han, Xiao; Cui, Fang-Yuan; Ren, Yi; Zou, Yi-Huai


    Abstract A large number of functional imaging studies have focused on the understanding of motor-related neural activities after ischemic stroke. However, the knowledge is still limited in the structural and functional changes of the interhemispheric connections of the bilateral primary motor cortices (M1s) and their potential influence on motor function recovery following stroke. Twenty-four stroke patients with right hemispheric subcortical infarcts and 25 control subjects were recruited to undergo multimodal magnetic resonance imaging examinations. Structural impairments between the bilateral M1s were measured by fractional anisotropy. Functional changes of the bilateral M1s were assessed via M1-M1 resting-state functional connectivity. Task-evoked activation analysis was applied to identify the roles of the bilateral hemispheres in motor function recovery. Compared with control subjects, unilateral subcortical stroke patients revealed significantly decreased fractional anisotropy and functional connectivity between the bilateral M1s. Stroke patients also revealed higher activations in multiple brain regions in both hemispheres and that more regions were located in the contralesional hemisphere. This study increased our understanding of the structural and functional alterations between the bilateral M1s that occur in unilateral subcortical stroke and provided further evidence for the compensatory role played by the contralesional hemisphere for these alterations during motor function recovery. PMID:27495109

  6. Structures of xyloglucans in primary cell walls of gymnosperms, monilophytes (ferns sensu lato) and lycophytes.

    Hsieh, Yves S Y; Harris, Philip J


    Little is known about the structures of the xyloglucans in the primary cell walls of vascular plants (tracheophytes) other than angiosperms. Xyloglucan structures were examined in 13 species of gymnosperms, 13 species of monilophytes (ferns sensu lato), and two species of lycophytes. Wall preparations were obtained, extracted with 6 M sodium hydroxide, and the extracts treated with a xyloglucan-specific endo-(1→4)-β-glucanase preparation. The oligosaccharides released were analysed by matrix-assisted laser-desorption ionisation time-of-flight mass spectrometry and by high-performance anion-exchange chromatography. The xyloglucan oligosaccharide profiles from the gymnosperm walls were similar to those from the walls of most eudicotyledons and non-commelinid monocotyledons, indicating that the xyloglucans were fucogalactoxyloglucans, containing the fucosylated units XXFG and XLFG. The xyloglucan oligosaccharide profiles for six of the monilophyte species were similar to those of the gymnosperms, indicating they were also fucogalactoxyloglucans. Phylogenetically, these monilophyte species were from both basal and more derived orders. However, the profiles for the other monilophyte species showed various significant differences, including additional oligosaccharides. In three of the species, these additional oligosaccharides contained arabinosyl residues which were most abundant in the profile of Equisetum hyemale. The two species of lycophytes examined, Selaginella kraussiana and Lycopodium cernuum, had quite different xyloglucan oligosaccharide profiles, but neither were fucogalactoxyloglucans. The S. kraussiana profile had abundant oligosaccharides containing arabinosyl residues. The L. cernuum profile indicated the xyloglucan had a very complex structure.

  7. Cine magnetic resonance imaging for evaluation of cardiac structure and flow dynamics in congenital heart disease

    Akagi, Teiji; Kiyomatsu, Yumi; Ohara, Nobutoshi; Takagi, Junichi; Sato, Noboru; Kato, Hirohisa (Kurume Univ., Fukuoka (Japan). School of Medicine); Eto, Takaharu


    Cine magnetic resonance imaging (Cine MRI) was performed in 20 patients aged 19 days to 13 years (mean 4.0 years), who had congenital heart disease confirmed at echocardiography or angiography. Prior to cine MRI, gated MRI was performed to evaluate for cardiac structure. Cine MRI was demonstrated by fast low fip angle shot imaging technique with a 30deg flip angle, 15 msec echo time, 30-40 msec pulse repetition time, and 128 x 128 acquisition matrix. Abnormalities of cardiac structure were extremely well defined in all patients by gated MRI. Intracardiac or intravascular blood flow were visualized in 17 (85%) of 20 patients by cine MRI. Left to right shunt flow through ventricular septal defect, atrial septal defect, and endocardial cushion defect were visualized with low signal intensity area. Low intensity jets flow through the site of re-coarctation of the aorta were also visualized. However, the good recording of cine MRI was not obtained because of artifacts in 3 of 20 patients (15%) who had severe congestive heart failure or respiratory arrhythmia. Gated MRI provides excellent visualization of fine structure, and cine MRI can provide high spatial resolution imaging of flow dynamic in a variety of congenital heart disease, noninvasively. (author).

  8. Structural features of the pore formed by Staphylococcus aureus alpha-toxin inferred from chemical modification and primary structure analysis.

    Menestrina, G; Belmonte, G; Parisi, V; Morante, S


    Staphylococcus aureus alpha-toxin makes cells and model membranes permeable to ions and uncharged molecules by opening oligomeric pores of uniform size. Its primary sequence reveals peculiar features which give some hints on the structure of the pore. A flexible region separating the toxin into two halves, several amphiphilic beta-strands and two amphiphilic alpha-helices long enough to span the hydrophobic core of the lipid bilayer are predicted. In analogy to bacterial porins, we propose that the inner walls of the pore are, at least in part, built by an amphiphilic beta-barrel. The model is consistent with circular dichroism data and with the electrophysiological properties of the pore. Functional information on this toxin were obtained by chemical modification of its four histidine residues. Specific carbethoxylation suggested they have different roles: one is required for specific receptor binding, one for oligomerisation and two for unspecific lipid binding. A tentative assignment of each histidine to its specific role is done on the basis of the structural predictions. A functionally related hemolysin, Aeromonas hydrophyla aerolysin, reveals remarkably similar features including the presence and location of histidines involved in receptor binding and oligomerisation.

  9. Diagnostics of spatial structure of vortex multiplets in a swirl flow

    Naumov, I. V.; Okulov, Valery; Sørensen, Jens Nørkær


    for different heights of this cylinder. The working liquid was 80-percent water-glycerin mixture, and small air bubbles were used as the tracers. The lid was rotated with a constant angular velocity under the studied conditions, and air was accumulated in the zones of decreased pressure on axes of vortices....... Visualization of flow structure for unstable swirl flows and cylinder aspect ratios from 3.2 to 5.5 allowed first identification of these regimes as multispiral breakdowns with formation of helical-like vortex duplets, triplets and quadruplets....

  10. Study of aerodynamic structure of flow in a model of vortex furnace using Stereo PIV method

    Anufriev, I. S.; Kuibin, P. A.; Shadrin, E. Yu.; Sharaborin, D. K.; Sharypov, O. V.


    The aerodynamic structure of flow in a lab model of a perspective design of vortex furnace was studied. The chamber has a horizontal rotation axis, tangential inlet for fuel-air jets and vertical orientation of secondary injection nozzles. The Stereo PIV method was used for visualization of 3D velocity field for selected cross sections of the vortex combustion chamber. The experimental data along with "total pressure minimum" criterion were used for reconstruction of the vortex core of the flow. Results fit the available data from LDA and simulation.

  11. Two-phase flow stability structure in a natural circulation system

    Zhou, Zhiwei [Nuclear Engineering Laboratory Zurich (Switzerland)


    The present study reports a numerical analysis of two-phase flow stability structures in a natural circulation system with two parallel, heated channels. The numerical model is derived, based on the Galerkin moving nodal method. This analysis is related to some design options applicable to integral heating reactors with a slightly-boiling operation mode, and is also of general interest to similar facilities. The options include: (1) Symmetric heating and throttling; (2) Asymmetric heating and symmetric throttling; (3) Asymmetric heating and throttling. The oscillation modes for these variants are discussed. Comparisons with the data from the INET two-phase flow stability experiment have qualitatively validated the present analysis.

  12. Mafic-crystal distributions, viscosities, and lava structures of some Hawaiian lava flows

    Rowland, Scott K.; Walker, George P. L.


    The distribution patterns of mafic phenocrysts in some Hawaiian basalt flows are consistent with simple in situ gravitational settling. We use the patterns to estimate the crystal settling velocity and hence viscosity of the lava, which in turn can be correlated with surface structures. Numerical modeling generates theoretical crystal concentration profiles through lava flow units of different thicknesses for differing settling velocities. By fitting these curves to field data, crystal-settling rates through the lavas can be estimated, from which the viscosities of the flows can be determined using Stokes' Law. Lavas in which the crystal settling velocity was relatively high (on the order of 5 × 10 -4 cm/sec) show great variations in phenocryst content, both from top to bottom of the same flow unit, and from one flow unit to another. Such lava is invariably pahoehoe, flow units of which are usually less than 1 m thick. Lavas in which the crystal-settling velocity was low show a small but measurable variation in phenocryst content. These lavas are part of a progression from a rough pahoehoe to toothpaste lava to a'a. Toothpaste lava is characterized by spiny texture as well as the ability to retain surface grooves during solidification, and flow units are usually thicker than 1 m. In the thickest of Hawaiian a'a flows, those of the distal type, no systematic crystal variations are observed, and high viscosity coupled with a finite yield strength prevented crystal settling. The amount of crystal settling in pahoehoe indicates that the viscosity ranged from 600 to 6000 Pa s. The limited amount of settling in toothpaste lava indicates a viscosity greater than this value, approaching 12,000 Pa s. We infer that distal-type a'a had a higher viscosity still and also possessed a yield strength.

  13. Periodical structure in a magnetic fluid under the action of an electric field and with a shear flow

    Veguera, Janna G. [Stavropol State University, 1 Pushkin st., Stavropol 355009 (Russian Federation)]. E-mail:; Dikansky, Yury I. [Stavropol State University, 1 Pushkin st., Stavropol 355009 (Russian Federation)


    The results of ordering structural formation in a flowing magnetic fluid under the action of an electric field are described. The influence of structural formation process on a viscosity and conductivity of this fluids has been considered.

  14. Lagrangian-based investigation of the transient flow structures around a pitching hydrofoil

    Wu, Qin; Huang, Biao; Wang, Guoyu


    The objective of this paper is to address the transient flow structures around a pitching hydrofoil by combining physical and numerical studies. In order to predict the dynamic behavior of the flow structure effectively, the Lagrangian coherent structures (LCS) defined by the ridges of the finite-time Lyapunov exponent (FTLE) are utilized under the framework of Navier-Stokes flow computations. In the numerical simulations, the k-ω shear stress transport (SST) turbulence model, coupled with a two-equation γ {-Re}_θ transition model, is used for the turbulence closure. Results are presented for a NACA66 hydrofoil undergoing slowly and rapidly pitching motions from 0° to 15° then back to 0° at a moderate Reynolds number Re=7.5× 105. The results reveal that the transient flow structures can be observed by the LCS method. For the slowly pitching case, it consists of five stages: quasi-steady and laminar, transition from laminar to turbulent, vortex development, large-scale vortex shedding, and reverting to laminar. The observation of LCS and Lagrangian particle tracers elucidates that the trailing edge vortex is nearly attached and stable during the vortex development stage and the interaction between the leading and trailing edge vortex caused by the adverse pressure gradient forces the vortexes to shed downstream during the large-scale vortex shedding stage, which corresponds to obvious fluctuations of the hydrodynamic response. For the rapidly pitching case, the inflection is hardly to be observed and the stall is delayed. The vortex formation, interaction, and shedding occurred once instead of being repeated three times, which is responsible for just one fluctuation in the hydrodynamic characteristics. The numerical results also show that the FTLE field has the potential to identify the transient flows, and the LCS can represent the divergence extent of infinite neighboring particles and capture the interface of the vortex region.

  15. Rabbit muscle creatine phosphokinase. CDNA cloning, primary structure and detection of human homologues.

    Putney, S; Herlihy, W; Royal, N; Pang, H; Aposhian, H V; Pickering, L; Belagaje, R; Biemann, K; Page, D; Kuby, S


    A cDNA library was constructed from rabbit muscle poly(A) RNA. Limited amino acid sequence information was obtained on rabbit muscle creatine phosphokinase and this was the basis for design and synthesis of two oligonucleotide probes complementary to a creatine kinase cDNA sequence which encodes a pentapeptide. Colony hybridizations with the probes and subsequent steps led to isolation of two clones, whose cDNA segments partially overlap and which together encode the entire protein. The primary structure was established from the sequence of two cDNA clones and from independently determined sequences of scattered portions of the polypeptide. The reactive cysteine has been located to position 282 within the 380 amino acid polypeptide. The rabbit cDNA hybridizes to digests of human chromosomal DNA. This reveals a restriction fragment length polymorphism associated with the human homologue(s) which hybridizes to the rabbit cDNA.

  16. Encoding of Primary Structures of Biological Macromolecules Within a Data Mining Perspective

    Mondher Maddouri; Mourad Elloumi


    An encoding method has a direct effect on the quality and the representation of the discovered knowledge in data mining systems. Biological macromolecules are encoded by strings of characters, called primary structures. Knowing that data mining systems usually use relational tables to encode data, we have then to reencode these strings and transform them into relational tables. In this paper, we do a comparative study of the existing static encoding methods, that are based on the Biologist know-how, and our new dynamic encoding one,that is based on the construction of Discriminant and Minimal Substrings (DMS). Different classification methods are used to do this study. The experimental results show that our dynamic encoding method is more efficient than the static ones, to encode biological macromolecules within a data mining perspective.

  17. Primary structure of Lep d I, the main Lepidoglyphus destructor allergen.

    Varela, J; Ventas, P; Carreira, J; Barbas, J A; Gimenez-Gallego, G; Polo, F


    The most relevant allergen of the storage mite Lepidoglyphus destructor (Lep d I) has been characterized. Lep d I is a monomer protein of 13273 Da. The primary structure of Lep d I was determined by N-terminal Edman degradation and partially confirmed by cDNA sequencing. Sequence polymorphism was observed at six positions, with non-conservative substitutions in three of them. No potential N-glycosylation site was revealed by peptide sequencing. The 125-residue sequence of Lep d I shows approximately 40% identity (including the six cysteines) with the overlapping regions of group II allergens from the genus Dermatophagoides, which, however, do not share common allergenic epitopes with Lep d I.

  18. Identification of new members of hydrophobin family using primary structure analysis

    Zhang Chaoyang


    Full Text Available Abstract Background Hydrophobins are fungal proteins that can turn into amphipathic membranes at hydrophilic/hydrophobic interfaces by self-assembly. The assemblages by Class I hydrophobins are extremely stable and possess the remarkable ability to change the polarity of the surface. One of its most important industrial applications is its usage as paint. Without detailed knowledge of the 3D structure and self-assembly principles of hydrophobins, it is difficult to make significant progress in furthering its research. Results In order to provide useful information to hydrophobin researchers, we analyzed primary structure of hydrophobins to gain more insight about these proteins. In this paper, we presented an in-depth primary sequence analysis using batch BLAST search of the database, sequence filtering by programming and motif finding by MEME. We used batch BLAST to find similar sequences in the NCBI nr database. Then we used MEME to find out motifs. Based on the newly found motifs and the well-known C-CC-C-C-CC-C pattern we used MAST to search the entire nr database. At the end, domain search and phylogenetic analysis were conducted to confirm the result. After searching the nr database with the new PSSM-format motifs identified by MEME, many sequences from various species were found by MAST. Filtering process by pattern, domain and length left 9 qualified candidates. Conclusion All of 9 newly identified potential hydrophobins possess the common pattern and hydrophobin domain. From the multiple sequence alignment result, we can see that some of them are grouped very close to other known hydrophobins, which means their phylogenetic relationship is very close and it is highly plausible that they are indeed hydrophobin proteins.

  19. Stop-flow Lithography to Continuously Fabricate Microlens Structures Utilizing an Adjustable Three-Dimensional Mask

    Shih-Hao Huang


    Full Text Available Stop-flow lithography (SFL is a microfluidic-based particle synthesis method, in which photolithography with a two dimensional (2D photomask is performed in situ within a microfluidic environment to fabricate multifunctional microstructures. Here, we modified the SFL technique by utilizing an adjustable electrostatic-force-modulated 3D (EFM-3D mask to continuously fabricate microlens structures for high-throughput production. The adjustable EFM-3D mask contains a layer filled with a UV-absorbing liquid and transparent elastomer structures in the shape of microlenses between two conductive glass substrates. An acrylate oligomer stream is photopolymerized via the microscope projection photolithography, where the EFM-3D mask was set at the field-stop plane of the microscope, thus forming the microlens structures. The produced microlens structures flow downstream without adhesion to the polydimethysiloxane (PDMS microchannel surfaces due to the existence of an oxygen-aided inhibition layer. Microlens structures with variations in curvature and aperture can be produced by changing objective magnifications, controlling the morphology of the EFM-3D mask through electrostatic force, and varying the concentration of UV-light absorption dyes. We have successfully demonstrated to produce microlens structures with an aperture ranging from 50 μm to 2 mm and the smallest focus spot size of 0.59 μm. Our proposed method allows one to fabricate microlens structures in a fast, simple and high-throughput mode for application in micro-optical systems.

  20. Identification of novel DNA repair proteins via primary sequence, secondary structure, and homology

    Akutsu Tatsuya


    Full Text Available Abstract Background DNA repair is the general term for the collection of critical mechanisms which repair many forms of DNA damage such as methylation or ionizing radiation. DNA repair has mainly been studied in experimental and clinical situations, and relatively few information-based approaches to new extracting DNA repair knowledge exist. As a first step, automatic detection of DNA repair proteins in genomes via informatics techniques is desirable; however, there are many forms of DNA repair and it is not a straightforward process to identify and classify repair proteins with a single optimal method. We perform a study of the ability of homology and machine learning-based methods to identify and classify DNA repair proteins, as well as scan vertebrate genomes for the presence of novel repair proteins. Combinations of primary sequence polypeptide frequency, secondary structure, and homology information are used as feature information for input to a Support Vector Machine (SVM. Results We identify that SVM techniques are capable of identifying portions of DNA repair protein datasets without admitting false positives; at low levels of false positive tolerance, homology can also identify and classify proteins with good performance. Secondary structure information provides improved performance compared to using primary structure alone. Furthermore, we observe that machine learning methods incorporating homology information perform best when data is filtered by some clustering technique. Analysis by applying these methodologies to the scanning of multiple vertebrate genomes confirms a positive correlation between the size of a genome and the number of DNA repair protein transcripts it is likely to contain, and simultaneously suggests that all organisms have a non-zero minimum number of repair genes. In addition, the scan result clusters several organisms' repair abilities in an evolutionarily consistent fashion. Analysis also identifies several

  1. Employing a Structured Interface to Advance Primary Students' Communicative Competence in a Text-Based Computer Mediated Environment

    Chiu, Chiung-Hui; Wu, Chiu-Yi; Hsieh, Sheng-Jieh; Cheng, Hsiao-Wei; Huang, Chung-Kai


    This study investigated whether a structured communication interface fosters primary students' communicative competence in a synchronous typewritten computer-mediated collaborative learning environment. The structured interface provided a set of predetermined utterance patterns for elementary students to use or imitate to develop communicative…

  2. Employing a Structured Interface to Advance Primary Students' Communicative Competence in a Text-Based Computer Mediated Environment

    Chiu, Chiung-Hui; Wu, Chiu-Yi; Hsieh, Sheng-Jieh; Cheng, Hsiao-Wei; Huang, Chung-Kai


    This study investigated whether a structured communication interface fosters primary students' communicative competence in a synchronous typewritten computer-mediated collaborative learning environment. The structured interface provided a set of predetermined utterance patterns for elementary students to use or imitate to develop communicative…

  3. Depth Averaged Equations Applied To Study of Defense Structures Effects On Dense Avalanche Flows

    Naaim, M.; Bouvet-Naaim, F.; Faug, T.; Lachamp, P.

    Avalanche zoning and protection devices are the complementary tools used to assess avalanche risk and protect persons and human activities in mountainous areas. Despite the intensive use of defense structures as protection against avalanches, their hydraulic and structural effects are not well known. Many structures were designed empirically using expert knowledge or knowledge developed in other domain such as hydraulic. Defence structures effects in terms of energy dissipation, deviation and snow retention are difficult to study in situ. The cost and difficulties of experiments, the danger and the weak annual number of avalanches in a given site, are the reasons why scientists oriented their research towards the use of numerical or laboratory physical models. This paper presents and discuss the possibilities to use depth averaged equations to study dense avalanche flows around defence structures. The used numerical resolu- tion method is based on an upwind numerical scheme. Equations are integrated on each cell of the mesh and the numerical fluxes are calculated thanks to a simplified Riemann solver where the retained solution is obtained as a combination of shock and rarefaction founctions. This allows taking into account the topography variation and jets and surges presence. These two characteristics are needed because both exper- imental and in situ observations showed a significant topography modifications and jets and surges formations during interaction between avalanche flows and structures. The case of vertical surfaces such as those made of concrete destined to deviate flows are treated by appropriated boundary condition functions. A discussion about the best way to integrate defence structures in such model is presented and discussed. This modelisation has, in a first time, been tested on analytical solutions and on experimen- tal laboratory scale model results. These tests have shown the capacity of this model, despite the strong hypothesis, to

  4. Controls of vegetation structure and net primary production in restored grasslands

    Munson, Seth M.; Lauenroth, William K.


    1. Vegetation structure and net primary production (NPP) are fundamental properties of ecosystems. Understanding how restoration practices following disturbance interact with environmental factors to control these properties can provide insight on how ecosystems recover and guide management efforts. 2. We assessed the relative contribution of environmental and restoration factors in controlling vegetation structure, above- and below-ground investment in production across a chronosequence of semiarid Conservation Reserve Program (CRP) fields recovering from dryland wheat cropping relative to undisturbed grassland. Importantly, we determined the role of plant diversity and how seeding either native or introduced perennial grasses influenced the recovery of vegetation properties. 3. Plant basal cover increased with field age and was highest in CRP fields seeded with native perennial grasses. In contrast, fields seeded with introduced perennial grasses had tall-growing plants with relatively low basal cover. These vegetation structural characteristics interacted with precipitation, but not soil characteristics, to influence above-ground NPP (ANPP). Fields enrolled in the CRP program for >7 years supported twice as much ANPP as undisturbed shortgrass steppe in the first wet year of the study, but all CRP fields converged on a common low amount of ANPP in the following dry year and invested less than half as much as the shortgrass steppe in below-ground biomass. 4. ANPP in CRP fields seeded with native perennial grasses for more than 7 years was positively related to species richness, whereas ANPP in CRP fields seeded with introduced perennial grasses were controlled more by dominant species. 5. Synthesis and applications. Seeding with introduced, instead of native, perennial grasses had a strong direct influence on vegetation structure, including species richness, which indirectly affected NPP through time. However, the effects of restoring either native or introduced


    麻伟巍; 谢锡麟; 周慧良


    The coherent structures and the chaotic phenomena in the transition of the axisymmetric countercurrent mixing shear flow were investigated experimentally. Two kinds of self-excited oscillation modes could exist in the axisymmetric countercurrent mixing shear flow. One is the shear layer self-excited oscillation mode corresponding to the high Reynolds number regime and the other is the jet column self-excited oscillation mode corresponding to the low Reynolds number regime in the case of the velocity ratio ranging from 1 to 1.5. Analyzing the auto-power spec trum, self-correlation-function and three dimensional reconstructed phase trajectory,the route to chaos through three Hopf bifurcations intercepted by an intermittence of the dynamical system corresponding to the axisymmetric countercurrent mixing shear flow was discovered when the velocity ratio is equal to 1.32.

  6. Identifying Coherent Structures in a 3-Stream Supersonic Jet Flow using Time-Resolved Schlieren Imaging

    Tenney, Andrew; Coleman, Thomas; Berry, Matthew; Magstadt, Andy; Gogineni, Sivaram; Kiel, Barry


    Shock cells and large scale structures present in a three-stream non-axisymmetric jet are studied both qualitatively and quantitatively. Large Eddy Simulation is utilized first to gain an understanding of the underlying physics of the flow and direct the focus of the physical experiment. The flow in the experiment is visualized using long exposure Schlieren photography, with time resolved Schlieren photography also a possibility. Velocity derivative diagnostics are calculated from the grey-scale Schlieren images are analyzed using continuous wavelet transforms. Pressure signals are also captured in the near-field of the jet to correlate with the velocity derivative diagnostics and assist in unraveling this complex flow. We acknowledge the support of AFRL through an SBIR grant.

  7. Recursive estimation of 3D motion and surface structure from local affine flow parameters.

    Calway, Andrew


    A recursive structure from motion algorithm based on optical flow measurements taken from an image sequence is described. It provides estimates of surface normals in addition to 3D motion and depth. The measurements are affine motion parameters which approximate the local flow fields associated with near-planar surface patches in the scene. These are integrated over time to give estimates of the 3D parameters using an extended Kalman filter. This also estimates the camera focal length and, so, the 3D estimates are metric. The use of parametric measurements means that the algorithm is computationally less demanding than previous optical flow approaches and the recursive filter builds in a degree of noise robustness. Results of experiments on synthetic and real image sequences demonstrate that the algorithm performs well.

  8. Numerical Investigation of the Flow Structure in a Kaplan Draft Tube at Part Load

    Maddahian, R.; Cervantes, M. J.; Sotoudeh, N.


    This research presents numerical simulation of the unsteady flow field inside the draft tube of a Kaplan turbine at part load condition. Due to curvature of streamlines, the ordinary two-equations turbulence models fail to predict the flow features. Therefore, a modification of the Shear Stress Transport (SST-SAS) model is utilized to approximate the turbulent stresses. A guide vane, complete runner and draft tube are considered to insure the real boundary conditions at the draft tube inlet. The outlet boundary is assumed to discharge into the atmosphere. The obtained pressure fluctuations inside the draft tube are in good agreement with available experimental data. In order to further investigate the RVR formation and its movement, the λ2 criterion, relating the position of the vortex core and strength to the second largest Eigen value of the velocity gradient tensor, is employed. The method used for vortex identification shows the flow structure and vortex motion inside the draft tube accurately.

  9. Interfacial structures of confined air-water two-phase bubbly flow

    Kim, S.; Ishii, M.; Wu, Q.; McCreary, D.; Beus, S.G.


    The interfacial structure of the two-phase flows is of great importance in view of theoretical modeling and practical applications. In the present study, the focus is made on obtaining detailed local two-phase parameters in the air-water bubbly flow in a rectangular vertical duct using the double-sensor conductivity probe. The characteristic wall-peak is observed in the profiles of the interracial area concentration and the void fraction. The development of the interfacial area concentration along the axial direction of the flow is studied in view of the interfacial area transport and bubble interactions. The experimental data is compared with the drift flux model with C{sub 0} = 1.35.

  10. Form and function in hillslope hydrology: in situ imaging and characterization of flow-relevant structures

    C. Jackisch


    Full Text Available The study deals with the identification and characterization of rapid subsurface flow structures through pedo- and geo-physical measurements and irrigation experiments at the point, plot and hillslope scale. Our investigation of flow-relevant structures and hydrological responses refers to the general interplay of form and function, respectively. To obtain a holistic picture of the subsurface, a large set of different laboratory, exploratory and experimental methods was used at the different scales. For exploration these methods included drilled soil core profiles, in situ measurements of infiltration capacity and saturated hydraulic conductivity, and laboratory analyses of soil water retention and saturated hydraulic conductivity. The irrigation experiments at the plot scale were monitored through a combination of dye tracer, salt tracer, soil moisture dynamics, and 3-D time-lapse ground penetrating radar (GPR methods. At the hillslope scale the subsurface was explored by a 3-D GPR survey. A natural storm event and an irrigation experiment were monitored by a dense network of soil moisture observations and a cascade of 2-D time-lapse GPR trenches. We show that the shift between activated and non-activated state of the flow paths is needed to distinguish structures from overall heterogeneity. Pedo-physical analyses of point-scale samples are the basis for sub-scale structure inference. At the plot and hillslope scale 3-D and 2-D time-lapse GPR applications are successfully employed as non-invasive means to image subsurface response patterns and to identify flow-relevant paths. Tracer recovery and soil water responses from irrigation experiments deliver a consistent estimate of response velocities. The combined observation of form and function under active conditions provides the means to localize and characterize the structures (this study and the hydrological processes (companion study Angermann et al., 2017, this issue.

  11. Form and function in hillslope hydrology: in situ imaging and characterization of flow-relevant structures

    Jackisch, Conrad; Angermann, Lisa; Allroggen, Niklas; Sprenger, Matthias; Blume, Theresa; Tronicke, Jens; Zehe, Erwin


    The study deals with the identification and characterization of rapid subsurface flow structures through pedo- and geo-physical measurements and irrigation experiments at the point, plot and hillslope scale. Our investigation of flow-relevant structures and hydrological responses refers to the general interplay of form and function, respectively. To obtain a holistic picture of the subsurface, a large set of different laboratory, exploratory and experimental methods was used at the different scales. For exploration these methods included drilled soil core profiles, in situ measurements of infiltration capacity and saturated hydraulic conductivity, and laboratory analyses of soil water retention and saturated hydraulic conductivity. The irrigation experiments at the plot scale were monitored through a combination of dye tracer, salt tracer, soil moisture dynamics, and 3-D time-lapse ground penetrating radar (GPR) methods. At the hillslope scale the subsurface was explored by a 3-D GPR survey. A natural storm event and an irrigation experiment were monitored by a dense network of soil moisture observations and a cascade of 2-D time-lapse GPR trenches. We show that the shift between activated and non-activated state of the flow paths is needed to distinguish structures from overall heterogeneity. Pedo-physical analyses of point-scale samples are the basis for sub-scale structure inference. At the plot and hillslope scale 3-D and 2-D time-lapse GPR applications are successfully employed as non-invasive means to image subsurface response patterns and to identify flow-relevant paths. Tracer recovery and soil water responses from irrigation experiments deliver a consistent estimate of response velocities. The combined observation of form and function under active conditions provides the means to localize and characterize the structures (this study) and the hydrological processes (companion study Angermann et al., 2017, this issue).

  12. Directed weighted network structure analysis of complex impedance measurements for characterizing oil-in-water bubbly flow

    Gao, Zhong-Ke; Dang, Wei-Dong; Xue, Le; Zhang, Shan-Shan


    Characterizing the flow structure underlying the evolution of oil-in-water bubbly flow remains a contemporary challenge of great interests and complexity. In particular, the oil droplets dispersing in a water continuum with diverse size make the study of oil-in-water bubbly flow really difficult. To study this issue, we first design a novel complex impedance sensor and systematically conduct vertical oil-water flow experiments. Based on the multivariate complex impedance measurements, we define modalities associated with the spatial transient flow structures and construct modality transition-based network for each flow condition to study the evolution of flow structures. In order to reveal the unique flow structures underlying the oil-in-water bubbly flow, we filter the inferred modality transition-based network by removing the edges with small weight and resulting isolated nodes. Then, the weighted clustering coefficient entropy and weighted average path length are employed for quantitatively assessing the original network and filtered network. The differences in network measures enable to efficiently characterize the evolution of the oil-in-water bubbly flow structures.

  13. Structured Composition of Dataflow and Control-Flow for Reusable and Robust Scientific Workflows

    Bowers, S; Ludaescher, B; Ngu, A; Critchlow, T


    Data-centric scientific workflows are often modeled as dataflow process networks. The simplicity of the dataflow framework facilitates workflow design, analysis, and optimization. However, some workflow tasks are particularly ''control-flow intensive'', e.g., procedures to make workflows more fault-tolerant and adaptive in an unreliable, distributed computing environment. Modeling complex control-flow directly within a dataflow framework often leads to overly complicated workflows that are hard to comprehend, reuse, schedule, and maintain. In this paper, we develop a framework that allows a structured embedding of control-flow intensive subtasks within dataflow process networks. In this way, we can seamlessly handle complex control-flows without sacrificing the benefits of dataflow. We build upon a flexible actor-oriented modeling and design approach and extend it with (actor) frames and (workflow) templates. A frame is a placeholder for an (existing or planned) collection of components with similar function and signature. A template partially specifies the behavior of a subworkflow by leaving ''holes'' (i.e., frames) in the subworkflow definition. Taken together, these abstraction mechanisms facilitate the separation and structured re-combination of control-flow and dataflow in scientific workflow applications. We illustrate our approach with a real-world scientific workflow from the astrophysics domain. This data-intensive workflow requires remote execution and file transfer in a semi-reliable environment. For such work-flows, we propose a 3-layered architecture: The top-level, typically a dataflow process network, includes Generic Data Transfer (GDT) frames and Generic remote eXecution (GX) frames. At the second level, the user can specialize the behavior of these generic components by embedding a suitable template (here: transducer templates for control-flow intensive tasks). At the third level, frames inside the

  14. Asymptotics, structure, and integration of sound-proof atmospheric flow equations

    Klein, Rupert


    Relative to the full compressible flow equations, sound-proof models filter acoustic waves while maintaining advection and internal waves. Two well-known sound-proof models, an anelastic model by Bannon and Durran’s pseudo-incompressible model, are shown here to be structurally very close to the full compressible flow equations. Essentially, the anelastic model is obtained by suppressing ∂ t ρ in the mass continuity equation and slightly modifying the gravity term, whereas the pseudo-incompressible model results from dropping ∂ t p from the pressure equation. For length scales small compared to the density and pressure scale heights, the anelastic model reduces to the Boussinesq approximation, while the pseudo-incompressible model approaches the zero Mach number, variable density flow equations. Thus, for small scales, both models are asymptotically consistent with the full compressible flow equations, yet the pseudo-incompressible model is more general in that it remains valid in the presence of large density variations. For the relatively small density variations found in typical atmosphere-ocean flows, both models are found to yield very similar results, with deviations between models much smaller than deviations obtained when using different numerical schemes for the same model. This in agreement with Smolarkiewicz and Dörnbrack (Int J Numer Meth Fluids 56:1513-1519, 2007). Despite these useful properties, neither model can be derived by a low-Mach number asymptotic expansion for length scales comparable to the pressure scale height, i.e., for the regime they were originally designed for. Derivations of these models via scale analysis ignore an asymptotic time scale separation between advection and internal waves. In fact, only the classical Ogura and Phillips model, which assumes weak stratification of the order of the Mach number squared, can be obtained as a leading-order model from systematic low Mach number asymptotic analysis. Issues of formal

  15. A field study of coherent flow structures over low angle dunes: Fraser Estuary, British Columbia

    Bradley, R. W.; Hendershot, M. L.; Venditti, J. G.; Kostaschuk, R. A.; Allison, M. A.; Church, M. A.


    Aqueous dunes are present in nearly all sand bedded alluvial channels and can significantly influence flow resistance and sediment transport and deposition. The geometry of these bedforms can take on a high angle asymmetrical or low angle symmetrical shape. While advances have been made in understanding the mean and turbulent flow over high angle dunes, far less progress has been made in detailing flow over low angle dunes, commonly observed in large rivers, due to difficulties measuring near the bed and quantifying the turbulence over these bedforms. This field study documents the flow over low angle dunes in the Fraser Estuary, British Columbia, using an acoustic Doppler profiler (aDcp) to measure 3-D flow characteristics and a multi-beam echo sounder (MBES) to provide high-resolution bed topography. Measurements were made over a dune field (~1 km long and ~0.5 wide) through two semi-diurnal tidal cycles during the 2010 freshet. We examine the coupling between the bedform morphology and the generation of coherent flow structures. Bedforms in the dune field range from low-angle symmetric to higher angle asymmetric and vary over tidal cycles; however, none display the classic angle of repose geometry. Mean flow velocity increases on falling tide while it decreases the rising tide. At lower tides, large scale motions caused by topographic forcing emerge on stoss slopes and rise up over the crest producing variations in suspended sediment over the bedforms. Our analysis is intended to contribute insight into what controls the occurrence of low angle bedforms in rivers.

  16. Structural Controls on Groundwater Flow in Basement Terrains: Geophysical, Remote Sensing, and Field Investigations in Sinai

    Mohamed, Lamees


    An integrated [very low frequency (VLF) electromagnetic, magnetic, remote sensing, field, and geographic information system (GIS)] study was conducted over the basement complex in southern Sinai (Feiran watershed) for a better understanding of the structural controls on the groundwater flow. The increase in satellite-based radar backscattering values following a large precipitation event (34 mm on 17–18 January 2010) was used to identify water-bearing features, here interpreted as preferred pathways for surface water infiltration. Findings include: (1) spatial analysis in a GIS environment revealed that the distribution of the water-bearing features (conductive features) corresponds to that of fractures, faults, shear zones, dike swarms, and wadi networks; (2) using VLF (43 profiles), magnetic (7 profiles) techniques, and field observations, the majority (85 %) of the investigated conductive features were determined to be preferred pathways for groundwater flow; (3) northwest–southeast- to north–south-trending conductive features that intersect the groundwater flow (southeast to northwest) at low angles capture groundwater flow, whereas northeast–southwest to east–west features that intersect the flow at high angles impound groundwater upstream and could provide potential productive well locations; and (4) similar findings are observed in central Sinai: east–west-trending dextral shear zones (Themed and Sinai Hinge Belt) impede south to north groundwater flow as evidenced by the significant drop in hydraulic head (from 467 to 248 m above mean sea level) across shear zones and by reorientation of regional flow (south–north to southwest–northeast). The adopted integrated methodologies could be readily applied to similar highly fractured basement arid terrains elsewhere. © 2015 Springer Science+Business Media Dordrecht

  17. Fluid-structure interaction for nonlinear response of shells conveying pulsatile flow

    Tubaldi, Eleonora; Amabili, Marco; Païdoussis, Michael P.


    Circular cylindrical shells with flexible boundary conditions conveying pulsatile flow and subjected to pulsatile pressure are investigated. The equations of motion are obtained based on the nonlinear Novozhilov shell theory via Lagrangian approach. The flow is set in motion by a pulsatile pressure gradient. The fluid is modeled as a Newtonian pulsatile flow and it is formulated using a hybrid model that contains the unsteady effects obtained from the linear potential flow theory and the pulsatile viscous effects obtained from the unsteady time-averaged Navier-Stokes equations. A numerical bifurcation analysis employs a refined reduced order model to investigate the dynamic behavior. The case of shells containing quiescent fluid subjected to the action of a pulsatile transmural pressure is also addressed. Geometrically nonlinear vibration response to pulsatile flow and transmural pressure are here presented via frequency-response curves and time histories. The vibrations involving both a driven mode and a companion mode, which appear due to the axial symmetry, are also investigated. This theoretical framework represents a pioneering study that could be of great interest for biomedical applications. In particular, in the future, a more refined model of the one here presented will possibly be applied to reproduce the dynamic behavior of vascular prostheses used for repairing and replacing damaged and diseased thoracic aorta in cases of aneurysm, dissection or coarctation. For this purpose, a pulsatile time-dependent blood flow model is here considered by applying physiological waveforms of velocity and pressure during the heart beating period. This study provides, for the first time in literature, a fully coupled fluid-structure interaction model with deep insights in the nonlinear vibrations of circular cylindrical shells subjected to pulsatile pressure and pulsatile flow.

  18. Experimental investigations on separation control and flow structure around a circular cylinder with synthetic jet

    WANG; JinJun; FENG; LiHao; XU; ChaoJun


    Circular cylinder separation control and flow structure influenced by the synthetic jet have been experimentally investigated in a water channel. The synthetic jet issues from a slot and ejects toward upstream from the front stagnation point of the cylinder. It has been found that, similar to the traditional synthetic jet which is positioned near the separation point or inside the separation region, the present synthetic jet arrangement constitutes an efficient way to control flow separation of the circular cylinder, but with a different control mechanism. The present synthetic jet leads to an upstream displacement of the front stagnation point and the formation of a vortex pair near both sides of the exit orifice. When ReU based on the synthetic jet average exit orifice velocity is about lower than 43, a closed envelope forms in front of the windward side of the cylinder during the blowing cycle of synthetic jet, which acts as an apparent modification for the cylinder configuration. When ReU is high enough, an open envelope forms upstream of the cylinder, and the flow around the cylinder becomes much energetic. Thus, regardless of ReU, the present synthetic jet can improve separation for flow around a circular cylinder. With regard to the leeward side, as ReU increases, the flow separation region behind the cylinder gradually disappears. The flow over cylinder may be fully attached when the open envelope forms upstream of the cylinder and ReU is greater than 344. Then, the flow past the cylinder will converge near the back stagnation point of the cylinder, where a new vortex pair shedding periodically is generated due to the high shear layer.

  19. Primary structure and chain conformation of fucoidan extracted from sea cucumber Holothuria tubulosa.

    Chang, Yaoguang; Hu, Yanfang; Yu, Long; McClements, David Julian; Xu, Xiaoqi; Liu, Guanchen; Xue, Changhu


    Knowledge of the structure of polysaccharides is essential for understanding and controlling their functional properties. In this study, fucoidan was extracted from Holothuria tubulosa, a species of sea cucumber that has recently become commercially important. The primary structure of the H. tubulosa fucoidan was clarified using a combination of enzymatic degradation, methylation analysis, and NMR, and its chain conformation was further elucidated by utilizing high performance size exclusion chromatography combined with multiple angle laser light scattering and viscometry. The fucoidan was composed of a tetrafucose repeating unit [ → 3-α-L-Fucp2(OSO3(-))-1 → 3-α-L-Fucp2,4(OSO3(-))-1 → 3-α-L-Fucp-1 → 3-α-L-Fucp2(OSO3(-))-1 → ]. Its sulfate content was determined to be 31.2 ± 1.6% and the weight-average molecular mass was 1567.6 ± 34.1 kDa. The molecule adapted a random coil conformation in 0.15M NaCl solution (pH 7.4) at 25 °C, with a root-mean-square radius of 63.9 ± 1.8 nm and a hydrodynamic radius of 44.5 ± 4.5 nm. This is the first report on the chain conformation of sea cucumber fucoidan.

  20. Identification of the gate regions in the primary structure of the secretin pIV.

    Spagnuolo, Julian; Opalka, Natacha; Wen, Wesley X; Gagic, Dragana; Chabaud, Elodie; Bellini, Pierdomenico; Bennett, Matthew D; Norris, Gillian E; Darst, Seth A; Russel, Marjorie; Rakonjac, Jasna


    Secretins are a family of large bacterial outer membrane channels that serve as exit ports for folded proteins, filamentous phage and surface structures. Despite the large size of their substrates, secretins do not compromise the barrier function of the outer membrane, implying a gating mechanism. The region in the primary structure that forms the putative gate has not previously been determined for any secretin. To identify residues involved in gating the pIV secretin of filamentous bacteriophage f1, we used random mutagenesis of the gene followed by positive selection for mutants with compromised barrier function ('leaky' mutants). We identified mutations in 34 residues, 30 of which were clustered into two regions located in the centre of the conserved C-terminal secretin family domain: GATE1 (that spanned 39 residues) and GATE2 (that spanned 14 residues). An internal deletion constructed in the GATE2 region resulted in a severely leaky phenotype. Three of the four remaining mutations are located in the region that encodes the N-terminal, periplasmic portion of pIV and could be involved in triggering gate opening. Two missense mutations in the 24-residue region that separates GATE1 and GATE2 were also constructed. These mutant proteins were unstable, defective in multimerization and non-functional.