Erysipelothrix endocarditis with previous cutaneous lesion: report of a case and review of the literature

Directory of Open Access Journals (Sweden)

Marion P. Rocha

1989-08-01

Full Text Available This report describes the first documented case of Erysipelothrix rhusiopathiae endocarditis in Latin America. The patient was a 51-years-old male, moderate alcoholic, with a previous history of aortic failure. He was used to fishing and cooking as a hobby and had his left hand wounded by a fish-bone. The disease began with erysipeloid form and developed to septicemia and endocarditis. He was treated with antibiotics and surgery for aortic valve replacement. There are only 46 cases of E. rhusiopathiae endocarditis reported to date. The authors wonder if several other cases might go unreported for lack of microbiological laboratorial diagnosis.

Recent changes of weather patterns in North America. Progress report for period ending April 1, 1994

International Nuclear Information System (INIS)

Kukla, G.J.; Karl, T.

1994-01-01

This report contains information dealing with climatic change in North America. Results gathered from present and previous DOE contracts are discussed. These include: usage of the Historical Climatology Network, characteristics of recent climate change, impacts of increasing anthropogenic greenhouse gases, seasonal trends, geographic and seasonal distribution of temperature anomalies, paleoclimates, weather pattern differences between eastern and western regions, daily temperature variations, general circulation models, and results of oceanic circulation

Lack of Cetuximab induced skin toxicity in a previously irradiated field: case report and review of the literature

Science.gov (United States)

2010-01-01

Introduction Mutation, amplification or dysregulation of the EGFR family leads to uncontrolled division and predisposes to cancer. Inhibiting the EGFR represents a form of targeted cancer therapy. Case report We report the case of 79 year old gentlemen with a history of skin cancer involving the left ear who had radiation and surgical excision. He had presented with recurrent lymph node in the left upper neck. We treated him with radiation therapy concurrently with Cetuximab. He developed a skin rash over the face and neck area two weeks after starting Cetuximab, which however spared the previously irradiated area. Conclusion The etiology underlying the sparing of the previously irradiated skin maybe due to either decrease in the population of EGFR expressing cells or decrease in the EGFR expression. We raised the question that "Is it justifiable to use EGFR inhibitors for patients having recurrence in the previously irradiated field?" We may need further research to answer this question which may guide the physicians in choosing appropriate drug in this scenario. PMID:20478052

Poly-epiphyseal overgrowth: description of a previously unreported skeletal dysplasia

Energy Technology Data Exchange (ETDEWEB)

Pazzaglia, Ugo E.; Bonaspetti, Giovanni [University of Brescia, Orthopaedic Clinic, Brescia (Italy); Beluffi, Giampiero [Fondazione IRCCS Policlinico San Matteo, Department of Paediatric Radiology, Pavia (Italy); Marchi, Antonietta; Bozzola, Mauro; Savasta, Salvatore [Fondazione IRCCS Policlinico San Matteo, Paediatric Clinic, University of Pavia, Pavia (Italy)

2007-10-15

A skeletal dysplasia with previously unreported features is presented. Its evolution was characterized by growth abnormalities of bones without involvement of other organs. Advanced bone age, increased stature and irregular epiphyseal ossification with stippling of the main long bones were documented. Physeal overgrowth was massive in the left proximal humerus and femur. Furthermore, the hip joint appeared fused with an abundant mass of pathological calcific tissue extending from the femur to the ilium. Pathological epiphyses were characterized by anarchic cartilaginous proliferation with multiple ossification centres, while lamellar bone apposition and remodelling were normal. The observed bone changes were different from those in any previously reported syndrome, metabolic defect or bone dysplasia. However, they clearly indicated a defect of endochondral ossification with some resemblance to phenotypes observed in dysplasia epiphysealis hemimelica. (orig.)

Poly-epiphyseal overgrowth: description of a previously unreported skeletal dysplasia

International Nuclear Information System (INIS)

Pazzaglia, Ugo E.; Bonaspetti, Giovanni; Beluffi, Giampiero; Marchi, Antonietta; Bozzola, Mauro; Savasta, Salvatore

2007-01-01

A skeletal dysplasia with previously unreported features is presented. Its evolution was characterized by growth abnormalities of bones without involvement of other organs. Advanced bone age, increased stature and irregular epiphyseal ossification with stippling of the main long bones were documented. Physeal overgrowth was massive in the left proximal humerus and femur. Furthermore, the hip joint appeared fused with an abundant mass of pathological calcific tissue extending from the femur to the ilium. Pathological epiphyses were characterized by anarchic cartilaginous proliferation with multiple ossification centres, while lamellar bone apposition and remodelling were normal. The observed bone changes were different from those in any previously reported syndrome, metabolic defect or bone dysplasia. However, they clearly indicated a defect of endochondral ossification with some resemblance to phenotypes observed in dysplasia epiphysealis hemimelica. (orig.)

75 FR 76056 - FEDERAL REGISTER CITATION OF PREVIOUS ANNOUNCEMENT:

Science.gov (United States)

2010-12-07

... SECURITIES AND EXCHANGE COMMISSION Sunshine Act Meeting FEDERAL REGISTER CITATION OF PREVIOUS ANNOUNCEMENT: STATUS: Closed meeting. PLACE: 100 F Street, NE., Washington, DC. DATE AND TIME OF PREVIOUSLY ANNOUNCED MEETING: Thursday, December 9, 2010 at 2 p.m. CHANGE IN THE MEETING: Time change. The closed...

Components of Inventory Change (CINCH) Reports

Data.gov (United States)

Department of Housing and Urban Development — The Components of Inventory Change (CINCH) report measures changes in the characteristics of the housing stock of the United States. Using data collected from the...

Adenylosuccinate lyase (ADSL) and infantile autism: Absence of previously reported point mutation

Energy Technology Data Exchange (ETDEWEB)

Fon, E.A.; Sarrazin, J.; Rouleau, G.A. [Montreal General Hospital (Canada)] [and others

1995-12-18

Autism is a heterogeneous neuropsychiatric syndrome of unknown etiology. There is evidence that a deficiency in the enzyme adenylosuccinate lyase (ADSL), essential for de novo purine biosynthesis, could be involved in the pathogenesis of certain cases. A point mutation in the ADSL gene, resulting in a predicted serine-to-proline substitution and conferring structural instability to the mutant enzyme, has been reported previously in 3 affected siblings. In order to determine the prevalence of the mutation, we PCR-amplified the exon spanning the site of this mutation from the genomic DNA of patients fulfilling DSM-III-R criteria for autistic disorder. None of the 119 patients tested were found to have this mutation. Furthermore, on preliminary screening using single-strand conformation polymorphism (SSCP), no novel mutations were detected in the coding sequence of four ADSL exons, spanning approximately 50% of the cDNA. In light of these findings, it appears that mutations in the ADSL gene represent a distinctly uncommon cause of autism. 12 refs., 2 figs.

Stevens-Johnson Syndrome Induced by Carbamazepine Treatment in a Patient Who Previously Had Carbamazepine Induced Pruritus - A Case Report -

OpenAIRE

Bae, Hyun Min; Park, Yoo Jung; Kim, Young Hoon; Moon, Dong Eon

2013-01-01

Stevens-Johnson syndrome (SJS) is a rare but life-threatening skin reaction disease and carbamazepine is one of its most common causes. We report a case of SJS secondary to carbamazepine in a patient with previous pruritus due to carbamazepine which was given for treatment of trigeminal neuralgia. We would like to caution all providers that carbamazepine readministration should be avoided in the patient with a previous history of SJS or adverse skin reaction. In addition, we strongly recommen...

Engineering change management report 2011

DEFF Research Database (Denmark)

Maier, Anja; Langer, Stefan

Changes or modifications have always been a fundamental part of product- and service design, yet they are often costly and potentially decrease overall development efficiency and effectiveness. How Danish manufacturing firms are able to improve engineering change management practice is a decisive......, challenges, and strategies for improved engineering change management of more than 90 engineering firms from different industry sectors and sizes in Denmark. In particular, the report presents an overview of current practice of engineering change management in Denmark, shows the extent to which engineering...... implementation, with software use in comparison being surprisingly low. The biggest problems listed range from engineering change process support to internal and external communication and the need for company-internal awareness and competence training for better engineering change management. The biggest need...

How business reporting changed during the financial crisis

DEFF Research Database (Denmark)

K. Muheki, Mark; Lueg, Klarissa; Lueg, Rainer

2014-01-01

have substantially changed their business reporting due to new regulations, the unfavorable economic situation, as well as strategic challenges like a loss in customer satisfaction. We thus conclude that business reporting can be seen—at least temporarily—as a tool for crisis communication. We document......Challenging times, such as the recent financial crisis, appear to cause organizations to change their business reporting. Yet, there is not much evidence how changes in business reporting were enacted by banks and there is only little discussion about to what extent this can be seen and assessed...... our findings along the four perspectives the banks use for their business reporting and that reflect the banks’ main stakeholders: shareholders, customers, employees, and the community....

Changes in nonhuman primate brain function following chronic alcohol consumption in previously naïve animals.

Science.gov (United States)

Rowland, Jared A; Stapleton-Kotloski, Jennifer R; Alberto, Greg E; Davenport, April T; Kotloski, Robert J; Friedman, David P; Godwin, Dwayne W; Daunais, James B

2017-08-01

Chronic alcohol abuse is associated with neurophysiological changes in brain activity; however, these changes are not well localized in humans. Non-human primate models of alcohol abuse enable control over many potential confounding variables associated with human studies. The present study utilized high-resolution magnetoencephalography (MEG) to quantify the effects of chronic EtOH self-administration on resting state (RS) brain function in vervet monkeys. Adolescent male vervet monkeys were trained to self-administer ethanol (n=7) or an isocaloric malto-dextrin solution (n=3). Following training, animals received 12 months of free access to ethanol. Animals then underwent RS magnetoencephalography (MEG) and subsequent power spectral analysis of brain activity at 32 bilateral regions of interest associated with the chronic effects of alcohol use. demonstrate localized changes in brain activity in chronic heavy drinkers, including reduced power in the anterior cingulate cortex, hippocampus, and amygdala as well as increased power in the right medial orbital and parietal areas. The current study is the first demonstration of whole-head MEG acquisition in vervet monkeys. Changes in brain activity were consistent with human electroencephalographic studies; however, MEG was able to extend these findings by localizing the observed changes in power to specific brain regions. These regions are consistent with those previously found to exhibit volume loss following chronic heavy alcohol use. The ability to use MEG to evaluate changes in brain activity following chronic ethanol exposure provides a potentially powerful tool to better understand both the acute and chronic effects of alcohol on brain function. Published by Elsevier B.V.

Pentagon's secret report about climate change

International Nuclear Information System (INIS)

Schwartz, P.

2006-01-01

This book reveals the content of a secret report ordered by the department of defense of the Pentagon which aims at foreseeing the possible consequences of a rapid climatic change on the security of the USA. The report is based on the most recent studies about the general climate conditions at the worldwide scale. They foresee for 2010 a fast cooling following several years of increasing warming up. A realistic detailed scenario of the geopolitical consequences of this change is made: floods, conflicts, populations migration, lack of drinkable water, starvation, generalized riots etc. (J.S.)

Transgender transitioning and change of self-reported sexual orientation.

Directory of Open Access Journals (Sweden)

Matthias K Auer

Full Text Available Sexual orientation is usually considered to be determined in early life and stable in the course of adulthood. In contrast, some transgender individuals report a change in sexual orientation. A common reason for this phenomenon is not known.We included 115 transsexual persons (70 male-to-female "MtF" and 45 female-to-male "FtM" patients from our endocrine outpatient clinic, who completed a questionnaire, retrospectively evaluating the history of their gender transition phase. The questionnaire focused on sexual orientation and recalled time points of changes in sexual orientation in the context of transition. Participants were further asked to provide a personal concept for a potential change in sexual orientation.In total, 32.9% (n = 23 MtF reported a change in sexual orientation in contrast to 22.2% (n = 10 FtM transsexual persons (p = 0.132. Out of these patients, 39.1% (MtF and 60% (FtM reported a change in sexual orientation before having undergone any sex reassignment surgery. FtM that had initially been sexually oriented towards males ( = androphilic, were significantly more likely to report on a change in sexual orientation than gynephilic, analloerotic or bisexual FtM (p = 0.012. Similarly, gynephilic MtF reported a change in sexual orientation more frequently than androphilic, analloerotic or bisexual MtF transsexual persons (p =0.05.In line with earlier reports, we reveal that a change in self-reported sexual orientation is frequent and does not solely occur in the context of particular transition events. Transsexual persons that are attracted by individuals of the opposite biological sex are more likely to change sexual orientation. Qualitative reports suggest that the individual's biography, autogynephilic and autoandrophilic sexual arousal, confusion before and after transitioning, social and self-acceptance, as well as concept of sexual orientation itself may explain this phenomenon.

Transgender transitioning and change of self-reported sexual orientation.

Science.gov (United States)

Auer, Matthias K; Fuss, Johannes; Höhne, Nina; Stalla, Günter K; Sievers, Caroline

2014-01-01

Sexual orientation is usually considered to be determined in early life and stable in the course of adulthood. In contrast, some transgender individuals report a change in sexual orientation. A common reason for this phenomenon is not known. We included 115 transsexual persons (70 male-to-female "MtF" and 45 female-to-male "FtM") patients from our endocrine outpatient clinic, who completed a questionnaire, retrospectively evaluating the history of their gender transition phase. The questionnaire focused on sexual orientation and recalled time points of changes in sexual orientation in the context of transition. Participants were further asked to provide a personal concept for a potential change in sexual orientation. In total, 32.9% (n = 23) MtF reported a change in sexual orientation in contrast to 22.2% (n = 10) FtM transsexual persons (p = 0.132). Out of these patients, 39.1% (MtF) and 60% (FtM) reported a change in sexual orientation before having undergone any sex reassignment surgery. FtM that had initially been sexually oriented towards males ( = androphilic), were significantly more likely to report on a change in sexual orientation than gynephilic, analloerotic or bisexual FtM (p = 0.012). Similarly, gynephilic MtF reported a change in sexual orientation more frequently than androphilic, analloerotic or bisexual MtF transsexual persons (p =0.05). In line with earlier reports, we reveal that a change in self-reported sexual orientation is frequent and does not solely occur in the context of particular transition events. Transsexual persons that are attracted by individuals of the opposite biological sex are more likely to change sexual orientation. Qualitative reports suggest that the individual's biography, autogynephilic and autoandrophilic sexual arousal, confusion before and after transitioning, social and self-acceptance, as well as concept of sexual orientation itself may explain this phenomenon.

Changing Mindsets: Evaluation Report and Executive Summary

Science.gov (United States)

Rienzo, Cinzia; Rolfe, Heather; Wilkinson, David

2015-01-01

The Changing Mindsets project sought to improve academic attainment by supporting pupils to develop a growth mindset: the belief that intelligence is not a fixed characteristic and can be increased through effort. Previous research (Good et al., 2003; Blackwell et al., 2007) has suggested that holding this belief enables pupils to work harder and…

Changing volatility of U.S. annual tornado reports

Science.gov (United States)

Tippett, Michael K.

2014-10-01

United States (U.S.) tornado activity results in substantial loss of life and property damage each year. A simple measure of the U.S. tornado climatology is the average number of tornadoes per year. However, even this statistic is elusive because of nonstationary behavior due in large part to changes in reporting practices. Differencing of the annual report data results in a quantity without mean trends and whose standard deviation we denote as volatility, since it is an indication of the likely year-to-year variation in the number of tornadoes reported. While volatility changes detected prior to 2000 can be associated with known reporting practice changes, an increase in volatility in the 2000s across intensity levels cannot. A volatility increase is also seen in a tornado environment index which measures the favorability of atmospheric conditions to tornado activity, providing evidence that the recent increase in tornado report volatility is related to the physical environment.

Climate Change Impacts on Human Health Due to Changes in Ambient Ozone Concentrations (External Review Draft)

Science.gov (United States)

This report uses results from a previous report titled Assessment of the Impacts of Global Change on Regional U.S. Air Quality: A Synthesis of Climate Change Impacts on Ground-Level Ozone, a number of high-resolution, spatially explicit population projections developed ...

Previously unreported abnormalities in Wolfram Syndrome Type 2.

Science.gov (United States)

Akturk, Halis Kaan; Yasa, Seda

2017-01-01

Wolfram syndrome (WFS) is a rare autosomal recessive disease with non-autoimmune childhood onset insulin dependent diabetes and optic atrophy. WFS type 2 (WFS2) differs from WFS type 1 (WFS1) with upper intestinal ulcers, bleeding tendency and the lack ofdiabetes insipidus. Li-fespan is short due to related comorbidities. Only a few familieshave been reported with this syndrome with the CISD2 mutation. Here we report two siblings with a clinical diagnosis of WFS2, previously misdiagnosed with type 1 diabetes mellitus and diabetic retinopathy-related blindness. We report possible additional clinical and laboratory findings that have not been pre-viously reported, such as asymptomatic hypoparathyroidism, osteomalacia, growth hormone (GH) deficiency and hepatomegaly. Even though not a requirement for the diagnosis of WFS2 currently, our case series confirm hypogonadotropic hypogonadism to be also a feature of this syndrome, as reported before. © Polish Society for Pediatric Endocrinology and Diabetology.

Left ventricular asynergy score as an indicator of previous myocardial infarction

International Nuclear Information System (INIS)

Backman, C.; Jacobsson, K.A.; Linderholm, H.; Osterman, G.

1986-01-01

Sixty-eight patients with coronary heart disease (CHD) i.e. a hisotry of angina of effort and/or previous 'possible infarction' were examined inter alia with ECG and cinecardioangiography. A system of scoring was designed which allowed a semiquantitative estimate of the left ventricular asynergy from cinecardioangiography - the left ventricular motion score (LVMS). The LVMS was associated with the presence of a previous myocardial infarction (MI), as indicated by the history and ECG findings. The ECG changes specific for a previous MI were associated with high LVMS values and unspecific or absent ECG changes with low LVMS values. Decision thresholds for ECG changes and asynergy in diagnosing a previous MI were evaluated by means of a ROC analysis. The accuracy of ECG in detecting a previous MI was slightly higher when asynergy indicated a 'true MI' than when autopsy result did so in a comparable group. Therefore the accuracy of asynergy (LVMS ≥ 1) in detecting a previous MI or myocardial fibrosis in patients with CHD should be at least comparable with that of autopsy (scar > 1 cm). (orig.)

Bioenergy, Land Use Change and Climate Change Mitigation. Report for Policy Advisors and Policy Makers

Energy Technology Data Exchange (ETDEWEB)

Berndes, Goran [Chalmers Univ. of Technology (Sweden); Bird, Nell [Joanneum Research (Austria); Cowle, Annette [National Centre for Rural Greenhouse Gas Research (Australia)

2010-07-01

The report addresses a much debated issue - bioenergy and associated land use change, and how the climate change mitigation from use of bioenergy can be influenced by greenhouse gas emissions arising from land use change. The purpose of the report was to produce an unbiased, authoritative statement on this topic aimed especially at policy advisors and policy makers.

47 CFR 1.787 - Reports of proposed changes in depreciation rates.

Science.gov (United States)

2010-10-01

... 47 Telecommunication 1 2010-10-01 2010-10-01 false Reports of proposed changes in depreciation... Reports and Requests § 1.787 Reports of proposed changes in depreciation rates. Carriers shall file reports regarding proposed changes in depreciation rates as required by part 43 of this chapter. ...

Preoperative screening: value of previous tests.

Science.gov (United States)

Macpherson, D S; Snow, R; Lofgren, R P

1990-12-15

To determine the frequency of tests done in the year before elective surgery that might substitute for preoperative screening tests and to determine the frequency of test results that change from a normal value to a value likely to alter perioperative management. Retrospective cohort analysis of computerized laboratory data (complete blood count, sodium, potassium, and creatinine levels, prothrombin time, and partial thromboplastin time). Urban tertiary care Veterans Affairs Hospital. Consecutive sample of 1109 patients who had elective surgery in 1988. At admission, 7549 preoperative tests were done, 47% of which duplicated tests performed in the previous year. Of 3096 previous results that were normal as defined by hospital reference range and done closest to the time of but before admission (median interval, 2 months), 13 (0.4%; 95% CI, 0.2% to 0.7%), repeat values were outside a range considered acceptable for surgery. Most of the abnormalities were predictable from the patient's history, and most were not noted in the medical record. Of 461 previous tests that were abnormal, 78 (17%; CI, 13% to 20%) repeat values at admission were outside a range considered acceptable for surgery (P less than 0.001, frequency of clinically important abnormalities of patients with normal previous results with those with abnormal previous results). Physicians evaluating patients preoperatively could safely substitute the previous test results analyzed in this study for preoperative screening tests if the previous tests are normal and no obvious indication for retesting is present.

30 CFR 70.220 - Status change reports.

Science.gov (United States)

2010-07-01

... MANDATORY HEALTH STANDARDS-UNDERGROUND COAL MINES Sampling Procedures § 70.220 Status change reports. (a) If there is a change in operational status that affects the respirable dust sampling requirements of this... produced. (iii) Abandoned—the work of all miners has been terminated and production activity has ceased. (2...

Chatham Islands Climate Change

International Nuclear Information System (INIS)

Mullan, B.; Salinger, J.; Thompson, C.; Ramsay, D.; Wild, M.

2005-06-01

This brief report provides guidance on climate change specific to the Chatham Islands, to complement the information recently produced for local government by the Ministry for the Environment in 'Climate Change Effects and Impacts Assessment: A guidance manual for Local Government in New Zealand' and 'Coastal Hazards and Climate Change: A guidance manual for Local Government in New Zealand'. These previous reports contain a lot of generic information on climate change, and how to assess associated risks, that is relevant to the Chatham Islands Council.

Relationship between staff-reported culture change and occupancy rate and organizational commitment among nursing homes in South Korea.

Science.gov (United States)

Lee, Minhong; Choi, Jae-Sung; Lim, Jinseop; Kim, Young Sun

2013-04-01

This study aims to examine culture change in nursing homes in South Korea and to identify the outcomes of culture change implementation. Data were taken from survey responses from 223 top- or mid-level staff among nursing homes in South Korea that were selected through a proportionate random-stratified sampling method from four regions nationwide. Culture change in nursing homes was operationalized by five person-directed care (PDC) constructs and three organizational environment constructs, and outcome quality was indicated by changes to occupancy rate and organizational commitment. After controlling for facility characteristics, the effect of staff-reported culture change on occupancy rate and organizational commitment was analyzed through the multiple-regression method. Consistent with previous research, this study revealed positive effects of culture change for nursing homes in South Korea. The study found that staff-reported culture change correlated with occupancy rate and organizational commitment. Given that culture change variables were significantly related to occupancy rate and organizational commitment, the findings of the study provide a persuasive argument that policies and/or programs to support culture change in nursing homes should be enhanced. Management-level workers in these facilities should have the skills and knowledge to foster more PDC and a more person-directed environment.

Retrospective analysis on malignant calcification previously misdiagnosed as benign on screening mammography

International Nuclear Information System (INIS)

Ha, Su Min; Cha, Joo Hee; Kim, Hak Hee; Shin, Hee Jung; Chae, Eun Young; Choi, Woo Jung

2017-01-01

The purpose of our study was to investigate the morphology and distribution of calcifications initially interpreted as benign or probably benign, but proven to be malignant by subsequent stereotactic biopsy, and to identify the reason for misinterpretation or underestimation at the initial diagnosis. Out of 567 women who underwent stereotactic biopsy for calcifications at our hospital between January 2012 and December 2014, 167 women were diagnosed with malignancy. Forty-six of these 167 women had previous mammography assessed as benign or probably benign which was changed to suspicious malignancy on follow-up mammography. Of these 46 women, three women with biopsy-proven benign calcifications at the site of subsequent cancer were excluded, and 43 patients were finally included. The calcifications (morphology, distribution, extent, associated findings) in the previous and follow-up mammography examinations were analyzed according to the Breast Imaging Reporting and Data System (BI-RADS) lexicon and assessment category. We classified the patients into two groups: 1) group A patients who were still retrospectively re-categorized as less than or equal to BI-RADS 3 and 2) group B patients who were re-categorized as equal to or higher than BI-RADS 4a and whose results should have prompted previous diagnostic assessment. In the follow-up mammography examinations, change in calcification morphology (n = 27, 63%) was the most frequent cause of assessment change. The most frequent previous mammographic findings of malignant calcification were amorphous morphology (n = 26, 60%) and grouped distribution (n = 36, 84%). The most frequent calcification findings at reassessment were amorphous morphology (n = 4, 9%), fine pleomorphic calcification (n = 30, 70%), grouped distribution (n = 23, 53%), and segmental calcification (n = 12, 28%). There were 33 (77%) patients in group A, and 10 patients (23%) in group B. Amorphous morphology and grouped distribution were the most frequent

Retrospective analysis on malignant calcification previously misdiagnosed as benign on screening mammography

Energy Technology Data Exchange (ETDEWEB)

Ha, Su Min [Dept. of Radiology, Research Institute of Radiology, Chung Ang University Hospital, Seoul(Korea, Republic of); Cha, Joo Hee; Kim, Hak Hee; Shin, Hee Jung; Chae, Eun Young; Choi, Woo Jung [Dept. of Radiology, Research Institute of Radiology, Asan Medical Center, University of Ulsan College of Medicine, Seoul (Korea, Republic of)

2017-04-15

The purpose of our study was to investigate the morphology and distribution of calcifications initially interpreted as benign or probably benign, but proven to be malignant by subsequent stereotactic biopsy, and to identify the reason for misinterpretation or underestimation at the initial diagnosis. Out of 567 women who underwent stereotactic biopsy for calcifications at our hospital between January 2012 and December 2014, 167 women were diagnosed with malignancy. Forty-six of these 167 women had previous mammography assessed as benign or probably benign which was changed to suspicious malignancy on follow-up mammography. Of these 46 women, three women with biopsy-proven benign calcifications at the site of subsequent cancer were excluded, and 43 patients were finally included. The calcifications (morphology, distribution, extent, associated findings) in the previous and follow-up mammography examinations were analyzed according to the Breast Imaging Reporting and Data System (BI-RADS) lexicon and assessment category. We classified the patients into two groups: 1) group A patients who were still retrospectively re-categorized as less than or equal to BI-RADS 3 and 2) group B patients who were re-categorized as equal to or higher than BI-RADS 4a and whose results should have prompted previous diagnostic assessment. In the follow-up mammography examinations, change in calcification morphology (n = 27, 63%) was the most frequent cause of assessment change. The most frequent previous mammographic findings of malignant calcification were amorphous morphology (n = 26, 60%) and grouped distribution (n = 36, 84%). The most frequent calcification findings at reassessment were amorphous morphology (n = 4, 9%), fine pleomorphic calcification (n = 30, 70%), grouped distribution (n = 23, 53%), and segmental calcification (n = 12, 28%). There were 33 (77%) patients in group A, and 10 patients (23%) in group B. Amorphous morphology and grouped distribution were the most frequent

Predicting changes in reported notifiable disease rates for New Zealand using a SIR modelling approach

Science.gov (United States)

McBride, Graham; Slaney, David; Tait, Andrew

2013-04-01

The New Zealand health system has defined as 'notifiable' over 50 diseases. Of these campylobacteriosis is the most commonly reported comprising 41% of all notifications in 2011 (presently about 150 illness cases per 100,000 population per annum). Furthermore, the incidence of this mild illness, which is potentially waterborne, is under-reported by at least an order-of-magnitude. Increased downstream pathogen loads and/or disease incidence have been found to be associated with increased rainfall, particularly in agricultural landscapes. Therefore, given the predominance of agricultural land uses in New Zealand, transmission and exposure to its agent (thermotolerant Campylobacter bacteria) may be affected by changing rainfall and temperature patterns associated with climate change. Reporting rates for other potentially water-borne zoonoses are also noticeable (for example, the reported rate for cryptosporidiosis for 2011 was 14 per 100,000 population). The distribution of Cryptosporidium oocysts in the environment may be influenced by climate change because it has often been implicated in drinking-water contamination, and heavy rainfall events have been found to be associated with increased pathogen loads in rivers and disease incidence. Given this background, which may also be applicable to other countries with agriculturally-dominated landscapes, a New Zealand study was initiated to develop a decision-support system for the projected effects of climate change on a selected suite of environmentally-transmitted pathogens, including Campylobacter and Cryptosporodium oocysts. Herein we report on the manner in which a linear SIR (Susceptible-Ill-Recovered) model previously developed for campylobacteriosis can be extended to cryptosporidiosis, applied to changes in pathogen contact rate and hence reported illness, and coupled to climate change projections associated with different greenhouse gas emission scenarios. The resulting SIR model outputs provided projected

Climate change in Australia: technical report 2007

International Nuclear Information System (INIS)

2007-01-01

The purpose of this report is to provide an up-to-date assessment of observed climate change over Australia, the likely causes, and projections of future changes to Australia's climate. It also provides information on how to apply the projections in impact studies and in risk assessments. The two main strategies for managing climate risk are mitigation (net reductions in greenhouse gas emissions) to slow climate change and adaptation to climate impacts that are unavoidable. A number of major advances have been made since the last report on climate change projections in Australia (CSIRO 2001) including: a much larger number of climate and ocean variables are projected (21 and 6 respectively); a much larger number (23) of climate models are used; the provision of probabilistic information on some of the projections, including the probability of exceeding the 10th, 50th and 90th percentiles; greater emphasis on projections from models that are better able to simulate observed Australian climate; a detailed assessment of observed changes in Australian climate and likely causes; and information on risk assessment, to provide guidance for using climate projections in impact studies

Components of Inventory Change (CINCH) reports 2007-2009

Data.gov (United States)

Department of Housing and Urban Development — The Components of Inventory Change (CINCH) report measures changes in the characteristics of the housing stock of the United States. Using data collected from the...

30 CFR 90.220 - Status change reports.

Science.gov (United States)

2010-07-01

... MANDATORY HEALTH STANDARDS-COAL MINERS WHO HAVE EVIDENCE OF THE DEVELOPMENT OF PNEUMOCONIOSIS Sampling Procedures § 90.220 Status change reports. If there is a change in the status of a part 90 miner that affects the respirable dust sampling requirements of this part (such as entering a terminated, injured or ill...

CCME Climate Change Indicators -- Workshop Report

International Nuclear Information System (INIS)

2000-01-01

In an effort to give Canadians a better understanding of the climate change issue, in 1999 the Canadian Council of Ministers of the Environment (CCME) established a Project Working Group to identify and assemble a set of climate change indicators that is scientifically valid, useful and meaningful to the public. To ensure the widest possible participation of experts from all parts of the country the Project Working Group convened a two-day workshop in Toronto to take place on the 6th and 7th of November 2000. The outcome of the workshop, summarized in this report, resulted in a 'Made in Canada' framework of indicators for climate change impacts, divided into five categories: physical environment, personal health and safety, jobs and economic well-being, social and community well-being, and eco-system health. The report contains highlights of the discussions. There are seven appendices containing, respectively, a series of pre-workshop suggestions for indicators (Appendix A), the workshop agenda and backgrounder (Appendix B), a list of participants (Appendix C), presentation slides on the Canada country study (Appendix D), existing and proposed climate change indicators (Appendix E), presentation slides on communication issues (Appendix F), and notes summarizing small group discussions, including assessment of the level of interest demonstrated and opinions expressed by group members about the utility and value of each of the proposed indicators (Appendix G)

Cerebral Metastasis from a Previously Undiagnosed Appendiceal Adenocarcinoma

Directory of Open Access Journals (Sweden)

Antonio Biroli

2012-01-01

Full Text Available Brain metastases arise in 10%–40% of all cancer patients. Up to one third of the patients do not have previous cancer history. We report a case of a 67-years-old male patient who presented with confusion, tremor, and apraxia. A brain MRI revealed an isolated right temporal lobe lesion. A thorax-abdomen-pelvis CT scan showed no primary lesion. The patient underwent a craniotomy with gross-total resection. Histopathology revealed an intestinal-type adenocarcinoma. A colonoscopy found no primary lesion, but a PET-CT scan showed elevated FDG uptake in the appendiceal nodule. A right hemicolectomy was performed, and the specimen showed a moderately differentiated mucinous appendiceal adenocarcinoma. Whole brain radiotherapy was administrated. A subsequent thorax-abdomen CT scan revealed multiple lung and hepatic metastasis. Seven months later, the patient died of disease progression. In cases of undiagnosed primary lesions, patients present in better general condition, but overall survival does not change. Eventual identification of the primary tumor does not affect survival. PET/CT might be a helpful tool in detecting lesions of the appendiceal region. To the best of our knowledge, such a case was never reported in the literature, and an appendiceal malignancy should be suspected in patients with brain metastasis from an undiagnosed primary tumor.

Predicting intraindividual changes in learning strategies: The effects of previous achievement

OpenAIRE

Buško, Vesna; Mujagić, Amela

2013-01-01

Socio-cognitive models of self-regulated learning (e.g., Pintrich, 2000) emphasize contextualized nature oflearning process, and within-person variation in learning processes, along with between-person variability in selfregulation.Previous studies about contextual nature of learning strategies have mostly focused on the effects ofdifferent contextual factors on interindividual differences in learning strategies utilization. However, less attentionwas given to the question about contextual ef...

A previously unreported variant of the synostotic sagittal suture: Case report and review of salient literature

Directory of Open Access Journals (Sweden)

Madison Budinich

2016-12-01

Full Text Available Introduction: Sagittal synostosis is a rare congenital disease caused by the premature fusion of the sagittal suture. Craniosynostosis occurs for a variety of reasons, different for every case, and often the etiology is unclear but the anomaly can frequently be seen as part of Crouzon's or Apert's syndromes. Herein, we discuss a rare case of craniosynostosis where the patient presented with a, to our knowledge, a previously undescribed variant of sagittal synostosis. Case report: A 3-month-old female infant presented to a craniofacial clinic for a consultation regarding an abnormal head shape. Images of the skull were performed, demonstrating that the patient had craniosynostosis. The patient displayed no other significant symptoms besides abnormalities in head shape. The sagittal suture was found to extend into the occipital bone where it was synostotic. Conclusion: To our knowledge, a synostotic sagittal suture has not been reported that extended posteriorly it involve the occipital bone. Those who interpret imaging or operate on this part of the skull should consider such a variation. Keywords: Anatomy, Craniosynostosis, Skull, Malformation, Pediatrics

Change in self-reported health status among immigrants in the United States: associations with measures of acculturation.

Science.gov (United States)

Lee, Sunmin; O'Neill, Allison H; Ihara, Emily S; Chae, David H

2013-01-01

Although acculturation may have positive effects for immigrants, including better socioeconomic profiles and increased occupational opportunities, their health profiles deteriorate with longer duration in the U.S. Prior research indicates that increasing acculturation is associated with some poorer health outcomes among immigrants in the U.S. However, most of these studies have used length of stay or English language proficiency as proxies for acculturation, and have mainly examined self-reported "current" health outcomes. This study advances knowledge on associations between acculturation and health among immigrants by explicitly examining self-reported "change" in health since immigration, in relation to acculturation-related variables. We use data from the New Immigrant Survey (NIS; 2003-2004), a cross-sectional study of legal immigrants to the U.S. In addition to testing more conventionally examined proxies of acculturation (length of stay and English proficiency), we also examine English language use and self-reported change in diet. Multivariable logistic regression analyses on 5,982 participants generally supported previous literature indicating a deleterious impact of acculturation, with increasing duration of stay and greater self-reported change in diet being associated with a poorer change in health since moving to the U.S. Although English language proficiency and use were associated with greater odds of reporting a worse change in health when examined individually, they were non-significant in multivariable models including all acculturation measures. Findings from this study suggest that when taking into account multiple measures of acculturation, language may not necessarily indicate unhealthy assimilation and dietary change may be a pathway leading to declines in immigrant health. Increasing duration in the U.S. may also reflect the adoption of unhealthy behaviors, as well as greater exposure to harmful sources of psychosocial stress including

Change in self-reported health status among immigrants in the United States: associations with measures of acculturation.

Directory of Open Access Journals (Sweden)

Sunmin Lee

Full Text Available Although acculturation may have positive effects for immigrants, including better socioeconomic profiles and increased occupational opportunities, their health profiles deteriorate with longer duration in the U.S. Prior research indicates that increasing acculturation is associated with some poorer health outcomes among immigrants in the U.S. However, most of these studies have used length of stay or English language proficiency as proxies for acculturation, and have mainly examined self-reported "current" health outcomes. This study advances knowledge on associations between acculturation and health among immigrants by explicitly examining self-reported "change" in health since immigration, in relation to acculturation-related variables. We use data from the New Immigrant Survey (NIS; 2003-2004, a cross-sectional study of legal immigrants to the U.S. In addition to testing more conventionally examined proxies of acculturation (length of stay and English proficiency, we also examine English language use and self-reported change in diet. Multivariable logistic regression analyses on 5,982 participants generally supported previous literature indicating a deleterious impact of acculturation, with increasing duration of stay and greater self-reported change in diet being associated with a poorer change in health since moving to the U.S. Although English language proficiency and use were associated with greater odds of reporting a worse change in health when examined individually, they were non-significant in multivariable models including all acculturation measures. Findings from this study suggest that when taking into account multiple measures of acculturation, language may not necessarily indicate unhealthy assimilation and dietary change may be a pathway leading to declines in immigrant health. Increasing duration in the U.S. may also reflect the adoption of unhealthy behaviors, as well as greater exposure to harmful sources of psychosocial

Climate change, global risks, challenges and decisions. Synthesis report

International Nuclear Information System (INIS)

Richardson, K.; Steffen, W.; Schellnhuber, H.J.

2009-03-01

The United Nations Framework Convention on Climate Change (UNFCCC) meeting to be held in Copenhagen in December 2009 (the 15th Conference of the Parties, COP-15) will be a critical step in developing a global response to the threat of climate change caused by human activities. The primary scientific input to those negotiations is the Fourth Assessment Report of the Intergovernmental Panel on Climate Change (IPCC), published in 2007. The IPCC report has already been instrumental in increasing both public and political awareness of the societal risks associated with unchecked emission of greenhouse gases. Since the production of the IPCC report, new knowledge has emerged that furthers understanding of the impacts of human influence on the climate and the response options and approaches that are available to tackle this complex issue. To bring this new knowledge together, the International Alliance of Research Universities organised an international scientific congress on climate change, Climate Change: Global Risks, Challenges and Decisions, which was held in Copenhagen from 10-12 March 2009. Participants came from nearly 80 different countries and contributed with more than 1400 scientific presentations. Abstracts for all of the scientific presentations made can be found at www.iop.org/EJ/volume/1755-1315/6, and a transcript of the closing plenary session can be found at environmentalresearchweb.org/cws/article/opinion/39126. This synthesis report presents an up-to-date overview of a broad range of research relevant to climate change - including fundamental climate science, the impacts of a changing climate on society and environment, and the many tools and approaches available to deal effectively with the challenge of climate change. (LN)

18 CFR 154.302 - Previously submitted material.

Science.gov (United States)

2010-04-01

... 18 Conservation of Power and Water Resources 1 2010-04-01 2010-04-01 false Previously submitted material. 154.302 Section 154.302 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY... concurrently with the rate change filing. There must be furnished to the Director, Office of Energy Market...

Climate and Land Use Change Effects on Ecological Resources in Three Watersheds: A Synthesis Report (Final Report)

Science.gov (United States)

EPA announced the availability of the final report, Climate and Land-Use Change Effects on Ecological Resources in Three Watersheds: A Synthesis Report. This report provides a summary of climate change impacts to selected watersheds and recommendations for how to improv...

Charged-particle thermonuclear reaction rates: IV. Comparison to previous work

International Nuclear Information System (INIS)

Iliadis, C.; Longland, R.; Champagne, A.E.; Coc, A.

2010-01-01

We compare our Monte Carlo reaction rates (see Paper II of this issue) to previous results that were obtained by using the classical method of computing thermonuclear reaction rates. For each reaction, the comparison is presented using two types of graphs: the first shows the change in reaction rate uncertainties, while the second displays our new results normalized to the previously recommended reaction rate. We find that the rates have changed significantly for almost all reactions considered here. The changes are caused by (i) our new Monte Carlo method of computing reaction rates (see Paper I of this issue), and (ii) newly available nuclear physics information (see Paper III of this issue).

Changes in the dominance hierarchy of captive female Japanese macaques as a consequence of merging two previously established groups.

Science.gov (United States)

Anderson, Emily J; Weladji, Robert B; Paré, Patrick

2016-11-01

Dominance hierarchies play an important role in reducing competition and aggression in social animals. In zoos, changes in group composition are often required due to management protocols, but these changes may have long lasting effects on dominance hierarchies, and, consequently, the wellbeing of the animals. We studied the changes in the female dominance hierarchy that occurred both during and after the formation of a group of 10 adult Japanese macaques at the Zoo de Granby by combining members from two previously established groups. There was no significant correlation between individual ranks in the old groups (groups A and B) and their ranks in the new group (group AB), indicating a significant change in the hierarchy. Alliances between kin appeared to be important in determining rank; when the sister of the dominant female was removed from group AB, the hierarchy changed significantly a second time. The average standardized rank of individuals added later in the formation process of group AB was not different from those added earlier. Ranks in the group AB did correlate with age of individual at the beginning of the field season, but not at the end, after the shift in hierarchy occurred. Zoo management must be aware of the consequences small changes in a social group can have when removing and transferring individuals in both primates and in other social species. Zoo Biol. 35:505-512, 2016. © 2016 Wiley Periodicals, Inc. © 2016 Wiley Periodicals, Inc.

False Balance in Climate Change Reporting Among TV Meteorologists

Science.gov (United States)

Timm, K.; Maibach, E.; Boykoff, M.; Broeckelman-Post, M.; Myers, T.; Perkins, D. R., IV

2017-12-01

False balance is the journalistic practice of giving equal weight to both sides of a story, regardless of an established truth and validity on one side. Despite widespread scientific agreement about the anthropogenic causes of climate change, false balance on the subject of climate change remains common in television despite a documented decline in other media. In this exploratory study, 452 American TV meteorologists were surveyed about their climate change beliefs and asked how often and why they present an opposing viewpoint when they present about human contributions to climate change. The results indicate that this practice is fairly common, with nearly 30% of TV meteorologists presenting an opposing viewpoint at least half the time or more frequently when they present about climate change. Weathercasters described including an opposing viewpoint in their stories for many different reasons, including that it is essential to objective and balanced reporting, that it is used to acknowledge different audience viewpoints, and because the science is perceived to be uncertain. The results also suggest that being more certain that climate change is happening, that it is primarily caused by humans, and perceiving the full extent of the scientific consensus about human-caused climate change, are associated with decreased frequency of presenting an opposing viewpoint. This is the first time the issue of false balance has been studied in the context of TV weathercasters, and while more research is needed, these results provide some preliminary evidence to suggest that increasing weathercasters' understanding of the scientific consensus of human caused climate change may help reduce false balance reporting. Furthermore, as meteorologists and weathercasters become more prominent reporters of local climate news, it will be important for them to have techniques to accurately report the science, while maintaining their sense of objectivity.

Summary of Previous Chamber or Controlled Anthrax Studies and Recommendations for Possible Additional Studies

Energy Technology Data Exchange (ETDEWEB)

Piepel, Gregory F.; Amidan, Brett G.; Morrow, Jayne B.

2010-12-29

This report and an associated Excel file(a) summarizes the investigations and results of previous chamber and controlled studies(b) to characterize the performance of methods for collecting, storing and/or transporting, extracting, and analyzing samples from surfaces contaminated by Bacillus anthracis (BA) or related simulants. This report and the Excel are the joint work of the Pacific Northwest National Laboratory (PNNL) and the National Institute of Standards and Technology (NIST) for the Department of Homeland Security, Science and Technology Directorate. The report was originally released as PNNL-SA-69338, Rev. 0 in November 2009 with limited distribution, but was subsequently cleared for release with unlimited distribution in this Rev. 1. Only minor changes were made to Rev. 0 to yield Rev. 1. A more substantial update (including summarizing data from other studies and more condensed summary tables of data) is underway

The Finnish research programme on climate change. Final report

Energy Technology Data Exchange (ETDEWEB)

Roos, J [ed.

1997-12-31

This is the final report of the Finnish Research Programme on Climate Change (SILMU). This report includes the final results and conclusions made by the individual research groups. The aim of this report is to lay out the research work, and to present the main results and conclusions obtained during the six-year work. The Finnish Research Programme on Climate Change (SILMU) was a multidisciplinary national research programme on climate and global change. The principal goals of SILMU were: (1) to increase our knowledge on climate change, its causes, mechanisms and consequences, (2) to strengthen the research on climate change in Finland, (3) to increase the participation of Finnish researchers in international research programmes, and (4) to prepare and disseminate information for policy makers on adaptation and mitigation. The key areas of the research were: (1) quantification of the greenhouse effect and the magnitude of anticipated climatic changes,(2) assessment of the effects of changing climate on ecosystems, and (3) development of mitigation and adaptation strategies. The research programme started in June 1990, and it comprised more than 80 individual research projects, ranging from atmospheric chemistry to economics. There were approximately two hundred scientists working within the programme in seven universities and eleven research institutions. The research activities that comprise SILMU were grouped into four interdisciplinary subprogrammes: atmosphere, waters, terrestrial ecosystems and integration and human interactions

The Finnish research programme on climate change. Final report

Energy Technology Data Exchange (ETDEWEB)

Roos, J. [ed.

1996-12-31

This is the final report of the Finnish Research Programme on Climate Change (SILMU). This report includes the final results and conclusions made by the individual research groups. The aim of this report is to lay out the research work, and to present the main results and conclusions obtained during the six-year work. The Finnish Research Programme on Climate Change (SILMU) was a multidisciplinary national research programme on climate and global change. The principal goals of SILMU were: (1) to increase our knowledge on climate change, its causes, mechanisms and consequences, (2) to strengthen the research on climate change in Finland, (3) to increase the participation of Finnish researchers in international research programmes, and (4) to prepare and disseminate information for policy makers on adaptation and mitigation. The key areas of the research were: (1) quantification of the greenhouse effect and the magnitude of anticipated climatic changes,(2) assessment of the effects of changing climate on ecosystems, and (3) development of mitigation and adaptation strategies. The research programme started in June 1990, and it comprised more than 80 individual research projects, ranging from atmospheric chemistry to economics. There were approximately two hundred scientists working within the programme in seven universities and eleven research institutions. The research activities that comprise SILMU were grouped into four interdisciplinary subprogrammes: atmosphere, waters, terrestrial ecosystems and integration and human interactions

47 CFR 43.43 - Reports of proposed changes in depreciation rates.

Science.gov (United States)

2010-10-01

... 47 Telecommunication 3 2010-10-01 2010-10-01 false Reports of proposed changes in depreciation... Reports of proposed changes in depreciation rates. (a) Each communication common carrier with annual..., before making any changes in the depreciation rates applicable to its operated plant, file with the...

Urethrotomy has a much lower success rate than previously reported.

Science.gov (United States)

Santucci, Richard; Eisenberg, Lauren

2010-05-01

We evaluated the success rate of direct vision internal urethrotomy as a treatment for simple male urethral strictures. A retrospective chart review was performed on 136 patients who underwent urethrotomy from January 1994 through March 2009. The Kaplan-Meier method was used to analyze stricture-free probability after the first, second, third, fourth and fifth urethrotomy. Patients with complex strictures (36) were excluded from the study for reasons including previous urethroplasty, neophallus or previous radiation, and 24 patients were lost to followup. Data were available for 76 patients. The stricture-free rate after the first urethrotomy was 8% with a median time to recurrence of 7 months. For the second urethrotomy stricture-free rate was 6% with a median time to recurrence of 9 months. For the third urethrotomy stricture-free rate was 9% with a median time to recurrence of 3 months. For procedures 4 and 5 stricture-free rate was 0% with a median time to recurrence of 20 and 8 months, respectively. Urethrotomy is a popular treatment for male urethral strictures. However, the performance characteristics are poor. Success rates were no higher than 9% in this series for first or subsequent urethrotomy during the observation period. Most of the patients in this series will be expected to experience failure with longer followup and the expected long-term success rate from any (1 through 5) urethrotomy approach is 0%. Urethrotomy should be considered a temporizing measure until definitive curative reconstruction can be planned. 2010 American Urological Association Education and Research, Inc. Published by Elsevier Inc. All rights reserved.

Unexpected finding of T-cell lymphoma in a previously healthy 16-year-old patient after a thorax trauma: a case report

DEFF Research Database (Denmark)

Bach Okholm-Hansen, Anna; Brorson, Stig

2014-01-01

INTRODUCTION: We describe the clinical course and emphasize the difficulties in diagnosing T-cell lymphoblastic lymphoma. The differential diagnostic difficulties have previously been described in regard to pneumonia, but to the best of the authors' knowledge this is the first case report to desc...... relevant to pediatricians, surgeons, anesthesiologists, and general practitioners....

Oral contraceptive use changes brain activity and mood in women with previous negative affect on the pill--a double-blinded, placebo-controlled randomized trial of a levonorgestrel-containing combined oral contraceptive.

Science.gov (United States)

Gingnell, Malin; Engman, Jonas; Frick, Andreas; Moby, Lena; Wikström, Johan; Fredrikson, Mats; Sundström-Poromaa, Inger

2013-07-01

Most women on combined oral contraceptives (COC) report high levels of satisfaction, but 4-10% complain of adverse mood effects. The aim of this randomized, double-blinded, placebo-controlled trial was to investigate if COC use would induce more pronounced mood symptoms than placebo in women with previous history of COC-induced adverse mood. A second aim was to determine if COC use is associated with changes in brain reactivity in regions previously associated with emotion processing. Thirty-four women with previous experience of mood deterioration during COC use were randomized to one treatment cycle with a levonorgestrel-containing COC or placebo. An emotional face matching task (vs. geometrical shapes) was administered during functional magnetic resonance imaging (fMRI) prior to and during the COC treatment cycle. Throughout the trial, women recorded daily symptom ratings on the Cyclicity Diagnoser (CD) scale. During the last week of the treatment cycle COC users had higher scores of depressed mood, mood swings, and fatigue than placebo users. COC users also had lower emotion-induced reactivity in the left insula, left middle frontal gyrus, and bilateral inferior frontal gyri as compared to placebo users. In comparison with their pretreatment cycle, the COC group had decreased emotion-induced reactivity in the bilateral inferior frontal gyri, whereas placebo users had decreased reactivity in the right amygdala. COC use in women who previously had experienced emotional side effects resulted in mood deterioration, and COC use was also accompanied by changes in emotional brain reactivity. These findings are of relevance for the understanding of how combined oral contraceptives may influence mood. Placebo-controlled fMRI studies in COC sensitive women could be of relevance for future testing of adverse mood effects in new oral contraceptives. Copyright © 2012 Elsevier Ltd. All rights reserved.

Signal intensity change on unenhanced T1-weighted images in dentate nucleus following gadobenate dimeglumine in patients with and without previous multiple administrations of gadodiamide

Energy Technology Data Exchange (ETDEWEB)

Ramalho, Joana [University of North Carolina Hospital, Chapel Hill, NC (United States); Centro Hospitalar de Lisboa Central, Lisbon (Portugal); Semelka, Richard C.; Castillo, Mauricio [University of North Carolina Hospital, Chapel Hill, NC (United States); AlObaidy, Mamdoh [University of North Carolina Hospital, Chapel Hill, NC (United States); King Faisal Specialist Hospital and Research Center, Riyadh (Saudi Arabia); Ramalho, Miguel [University of North Carolina Hospital, Chapel Hill, NC (United States); Hospital Garcia de Orta, Almada (Portugal); Nunes, Renato H. [University of North Carolina Hospital, Chapel Hill, NC (United States); Santa Casa de Misericordia de Sao Paulo, Sao Paulo (Brazil)

2016-11-15

To evaluate the impact of previous administration of gadodiamide and neural tissue gadolinium deposition in patients who received gadobenate dimeglumine. Our population included 62 patients who underwent at least three administrations of gadobenate dimeglumine, plus an additional contrast-enhanced last MRI for reference, divided into two groups: group 1, patients who in addition to gadobenate dimeglumine administrations had prior exposure to multiple doses of gadodiamide; group 2, patients without previous exposure to other gadolinium-based contrast agent (GBCAs). Quantitative analysis was performed on the first and last gadobenate dimeglumine MRIs in both groups. Dentate nucleus-to-middle cerebellar peduncle signal intensity ratios (DN/MCP) and relative change (RC) in signal over time were calculated and compared between groups using generalized additive model. Group 1 showed significant increase in baseline and follow-up DN/MCP compared to group 2 (p < 0.0001). The RC DN/MCP showed a non-statistically significant trend towards an increase in patients who underwent previous gadodiamide (p = 0.0735). There is increased T1 signal change over time in patients who underwent gadobenate dimeglumine and had received prior gadodiamide compared to those without known exposure to previous gadodiamide. A potentiating effect from prior gadodiamide on subsequent administered gadobenate dimeglumine may occur. (orig.)

Climate change : we are at risk : interim report

International Nuclear Information System (INIS)

Oliver, D.; Wiebe, J.

2003-06-01

Between November 2002 and May 2003 the Standing Senate Committee on Agriculture and Forestry travelled across Canada to hear the views of farmer organizations, rural associations, ecotourism groups and environmental organizations regarding concerns about climate change and the impact it may have on the agriculture and forestry sectors and rural communities. The Committee also examined potential adaptation strategies focusing on primary production, practices, technologies, ecosystems and other related areas. Farmers and forest operators are already facing changes in market conditions, domestic regulations, trade policies and technology. This interim report expressed the concerns of farmers and forest operators. It includes a review of the Saguenay flood of 1996, the Red River flood of 1997, the ice storm of 1998, and droughts since 1999. It also includes a discussion on climate change and its biophysical and economic effects on agriculture, forestry, water resources, rural communities, and Aboriginal communities. This interim report also briefly outlines the Kyoto Protocol, the emissions trading system, and the decarbonization of global energy systems. It emphasized the need for integrated research and government policies and programs that encourage adaptation to climate change. The final report will be released in October 2003 and will provide specific recommendations to ensure that Canada responds to the concerns of farmers and forest operators and to ensure continued prosperity in these sectors. refs., figs

Climate change : we are at risk : interim report

Energy Technology Data Exchange (ETDEWEB)

Oliver, D.; Wiebe, J.

2003-06-01

Between November 2002 and May 2003 the Standing Senate Committee on Agriculture and Forestry travelled across Canada to hear the views of farmer organizations, rural associations, ecotourism groups and environmental organizations regarding concerns about climate change and the impact it may have on the agriculture and forestry sectors and rural communities. The Committee also examined potential adaptation strategies focusing on primary production, practices, technologies, ecosystems and other related areas. Farmers and forest operators are already facing changes in market conditions, domestic regulations, trade policies and technology. This interim report expressed the concerns of farmers and forest operators. It includes a review of the Saguenay flood of 1996, the Red River flood of 1997, the ice storm of 1998, and droughts since 1999. It also includes a discussion on climate change and its biophysical and economic effects on agriculture, forestry, water resources, rural communities, and Aboriginal communities. This interim report also briefly outlines the Kyoto Protocol, the emissions trading system, and the decarbonization of global energy systems. It emphasized the need for integrated research and government policies and programs that encourage adaptation to climate change. The final report will be released in October 2003 and will provide specific recommendations to ensure that Canada responds to the concerns of farmers and forest operators and to ensure continued prosperity in these sectors. refs., figs.

Placenta Percreta Invading Broad Ligament and Parametrium in a Woman with Two Previous Cesarean Sections: A Case Report

Directory of Open Access Journals (Sweden)

Mansoureh Vahdat

2012-01-01

Full Text Available Introduction. The incidence of placenta accreta has dramatically increased due to increasing caesarean section rate all over the world. Placenta percreta is the most severe form of placenta accretes. It frequently results in maternal morbidity and mortality mainly caused by massive obstetric hemorrhage or emergency hysterectomy. Percreta invading into the broad ligament has rarely been previously reported. Case presenting. We presented a case of placenta percreta invading left broad ligament and parametrium in a woman with two previous cesarean sections, which led to massive intraoperative hemorrhage during hysterectomy and transient ischemic encephalopathy. Conclusion. In cases of parametrial involvement, it would be more difficult to decide whether to remove placenta or leave it in site. In surgical removal neither local excision of placental bed and uterine repair nor traditional hysterectomy is adequate if parametrium invaded by placenta. We suggest delayed elective hysterectomy in such cases. So, pregnancy-induced pelvic congestion would be decreased, we can gather an expert team of gynecologists, urologists, and vascular surgeons, we could get plenty of blood products, and we may have the chance to administer methotrexate.

Report of a seminar on natural environmental change

International Nuclear Information System (INIS)

1989-01-01

This document reports the presentations given at a seminar on Natural Environmental Change: Processes Affecting the Deep Disposal of Radioactive Waste in Britain and the ensuing discussion. Following introductory summaries of the Department of the Environment research programme into radioactive waste management and Nirex-funded research into long-term environmental change, four topical presentations were given, namely, ''Climatic Change'', ''Surface Processes'', and ''Stress and Seismicity''. These presentations and the consequent discussion have served to clarify many key aspects of long-term environmental change and have provided direction to the ongoing studies of the effects of environmental change on the performance of deep radioactive waste disposal facilities. (author)

U.S. Global Climate Change Impacts Report, Adaptation

Science.gov (United States)

Pulwarty, R.

2009-12-01

Adaptation measures improve our ability to cope with or avoid harmful climate impacts and take advantage of beneficial ones, now and as climate varies and changes. Adaptation and mitigation are necessary elements of an effective response to climate change. Adaptation options also have the potential to moderate harmful impacts of current and future climate variability and change. The Global Climate Change Impacts Report identifies examples of adaptation-related actions currently being pursued in various sectors and regions to address climate change, as well as other environmental problems that could be exacerbated by climate change such as urban air pollution and heat waves. Some adaptation options that are currently being pursued in various regions and sectors to deal with climate change and/or other environmental issues are identified in this report. A range of adaptation responses can be employed to reduce risks through redesign or relocation of infrastructure, sustainability of ecosystem services, increased redundancy of critical social services, and operational improvements. Adapting to climate change is an evolutionary process and requires both analytic and deliberative decision support. Many of the climate change impacts described in the report have economic consequences. A significant part of these consequences flow through public and private insurance markets, which essentially aggregate and distribute society's risk. However, in most cases, there is currently insufficient robust information to evaluate the practicality, efficiency, effectiveness, costs, or benefits of adaptation measures, highlighting a need for research. Adaptation planning efforts such as that being conducted in New York City and the Colorado River will be described. Climate will be continually changing, moving at a relatively rapid rate, outside the range to which society has adapted in the past. The precise amounts and timing of these changes will not be known with certainty. The

Ethnicity and parental report of postoperative behavioral changes in children.

Science.gov (United States)

Fortier, Michelle A; Tan, Edwin T; Mayes, Linda C; Wahi, Aditi; Rosenbaum, Abraham; Strom, Suzanne; Santistevan, Ricci; Kain, Zeev N

2013-05-01

To examine the role of ethnicity and language in parent report of children's postoperative behavioral recovery. To compare incidence of new onset negative behavior change in English- and Spanish-speaking White and Hispanic children following outpatient surgery. Postoperative behavioral change in children is common; however, it is unknown whether cultural variables including ethnicity and language may influence parent report of children's behavioral recovery. Participants included 288 parents (English-speaking White, English-speaking Hispanic, Spanish-speaking Hispanic parents) of children undergoing outpatient elective surgery. Parents completed the post-hospitalization behavior questionnaire (PHBQ) and parents' postoperative pain measure (PPPM) on postoperative days one, three, and seven at home. Most parents (83%) reported onset of new negative behavioral change in children postoperatively. Generalized estimating equations revealed significant group differences in overall behavior change [Wald χ(2)(12) = 375.69, P children compared to English-speaking White (ESW) parents (day 1: P children's postoperative behavioral recovery may be influenced by cultural variables, such as ethnicity and language. The present results contribute to a growing body of evidence that highlights the need for culturally sensitive assessment and care of families in the medical setting. The findings may reflect differences in cultural values such as stoicism; however, future studies would benefit from examination of the factors that may account for the differences in reported behavior change after surgery (i.e., report bias, cultural values). © 2012 Blackwell Publishing Ltd.

Iodine-131 induced hepatotoxicity in previously healthy patients with Grave's disease.

Science.gov (United States)

Jhummon, Navina Priya; Tohooloo, Bhavna; Qu, Shen

2013-01-01

To describe the association of the rare and serious complication of liver toxicity in previously healthy Grave's disease (GD) patients after the treatment with radioactive iodine (131)I (RAI). We report the clinical, laboratory and pathologic findings of 2 cases of severe liver toxicity associated with the treatment with RAI in previously healthy patients with GD. Clinical examination and laboratory investigations excluded viral hepatitis, autoimmune hepatitis, granulomatous disease, primary biliary disease, extrahepatic biliary obstruction, and heart failure. Case 1: A previously healthy 52-years old man reportedly having a typical GD but following RAI treatment, concomitantly developed severe liver toxicity that required 1 week of treatment in hospital. Case 2: A previously healthy 34-years old woman is reported as having a typical GD but developed jaundice following RAI treatment that required several weeks of in hospital treatment in the hepato-biliary department. In both cases, the liver dysfunction resolved after intensive treatment with hepato-protective agents. In this report the therapeutic considerations as well as the pathogenetic possibilities are reviewed. To the best of our knowledge, this is the first description of the association observed, which is rare but may be severe and should be considered in any case of thyrotoxicosis where a liver dysfunction develops after the treatment with radioactive iodine (131)I.

Changing Morning Report: An Educational Intervention to Address Curricular Needs

Directory of Open Access Journals (Sweden)

Vijay John Daniels

2014-01-01

Full Text Available Morning report is a case-based teaching session common to many residency programs with varying purposes and focuses. At our institution, physicians and residents felt our Internal Medicine morning report had lost its educational focus. The purpose of this project was to improve morning report using a well-known curriculum development framework for medical education. We conducted a focus group of residents to develop and implement changes to morning report. Themes from our focus group led us to split morning report with the first 30 minutes for postgraduate year 3 (PGY-3 residents to give handover, to receive feedback on diagnosis and management, and to either discuss an interesting case or receive teaching aimed at their final certification examination. The second 30 minutes involved PGY-3 residents leading PGY-1 residents in case-based discussions with an attending physician providing feedback on the content and process of teaching. We measured success based on a follow-up survey and comments from resident evaluations before and after the change. Overall, the changes were well received by both faculty and residents; however comments revealed that the success of morning report is preceptor dependent. In summary, we have successfully implemented a split morning report model to enhance resident education with positive feedback.

Enhancing reporting of behavior change intervention evaluations

NARCIS (Netherlands)

Abraham, C.; Johnson, B.T.; de Bruin, M.; Luszczynska, A.

2014-01-01

Many behavior change interventions for the prevention and treatment of HIV have been evaluated, but suboptimal reporting of evaluations hinders the accumulation of evidence and the replication of interventions. In this article, we address 4 practices contributing to this problem. First, detailed

USERS NEEDS: A PREMISE FOR CORPORATE REPORTING CHANGE

OpenAIRE

Farcas Teodora Viorica

2015-01-01

The topic of corporate reporting is very actual being subject of preoccupation of the main international regulatory and professional organisms in the accounting area. Hence, our study targets a priority research area. Its main objective is to discuss the concept of user needs and to emphasize how the needs of users of corporate financial reports have developed in time and how these needs are the main factors influencing the actual changes in the framework of the corporate reporting. In the no...

[Prevalence of previously diagnosed diabetes mellitus in Mexico.

Science.gov (United States)

Rojas-Martínez, Rosalba; Basto-Abreu, Ana; Aguilar-Salinas, Carlos A; Zárate-Rojas, Emiliano; Villalpando, Salvador; Barrientos-Gutiérrez, Tonatiuh

2018-01-01

To compare the prevalence of previously diagnosed diabetes in 2016 with previous national surveys and to describe treatment and its complications. Mexico's national surveys Ensa 2000, Ensanut 2006, 2012 and 2016 were used. For 2016, logistic regression models and measures of central tendency and dispersion were obtained. The prevalence of previously diagnosed diabetes in 2016 was 9.4%. The increase of 2.2% relative to 2012 was not significant and only observed in patients older than 60 years. While preventive measures have increased, the access to medical treatment and lifestyle has not changed. The treatment has been modified, with an increase in insulin and decrease in hypoglycaemic agents. Population aging, lack of screening actions and the increase in diabetes complications will lead to an increase on the burden of disease. Policy measures targeting primary and secondary prevention of diabetes are crucial.

30 CFR 71.220 - Status change reports.

Science.gov (United States)

2010-07-01

... MANDATORY HEALTH STANDARDS-SURFACE COAL MINES AND SURFACE WORK AREAS OF UNDERGROUND COAL MINES Sampling... respirable dust sampling requirements of this part, the operator shall report the change in operational...—no material is being produced. (iii) Abandoned—the work of all miners has been terminated and...

Hearing loss prevention education using adopt-a-band: changes in self-reported earplug use in two high school marching bands.

Science.gov (United States)

Auchter, Melissa; Le Prell, Colleen G

2014-06-01

Hearing loss prevention has always been an important issue for audiologists. The importance of hearing loss prevention education for young musicians is now recognized by the National Association for Music Education as well as the National Association of Schools of Music. Adopt-a-Band is a commercial program designed to foster hearing loss prevention behavior in young musicians. This study assessed changes in earplug use, measured using self-report surveys, after Adopt-a-Band training. Participants were members of 2 high school marching bands who viewed an informational DVD and reviewed fact sheets. Flat-attenuation earplugs were distributed, and training was provided. In addition, study participants engaged in discussion of hearing loss with a doctor of audiology student. Before training, 23% of participants reported they had previously used hearing protection. Immediately after training, 94% of participants reported they planned to use hearing protection at least occasionally. In a final end-of-season survey, earplug use had reliably increased; 62% of participants reported they used earplugs at least occasionally. Earplug use increased, but self-reported behavioral change was not as robust as predicted from self-reported participant intentions. Participant comments regarding factors that influenced their earplug use decisions suggest opportunities to improve training.

Climate change adaptation in Africa : annual report 2006-2007

International Nuclear Information System (INIS)

2007-01-01

The Climate Change Adaptation Program was developed by Canada's International Development Research Centre and the United Kingdom's Department for International Development in order to address the needs of African communities vulnerable to climate change. The objectives of the program are to strengthen the capacity of African scientists, organization and communities to contribute to adaptation to climate change, as well as to generate a better understanding of climate change adaptation, and to support adaptation strategies and their adoption by rural and urban Africans. This annual report provided details of the first year of the program's implementation, in which an advisory board was established in order to balance donor representation and African expertise in adaptation. The first year of the program also saw the recruitment of a 13 person staff and the development of proposals for the first allocation of funding. A financial summary was provided. The report provided details of outreach and communications activities used to introduce the program to African and international audiences. 3 tabs., 44 figs

Shunt malfunction causing acute neurological deterioration in 2 patients with previously asymptomatic Chiari malformation Type I. Report of two cases.

Science.gov (United States)

Elliott, Robert; Kalhorn, Stephen; Pacione, Donato; Weiner, Howard; Wisoff, Jeffrey; Harter, David

2009-08-01

Patients with symptomatic Chiari malformation Type I (CM-I) typically exhibit a chronic, slowly progressive disease course with evolution of symptoms. However, some authors have reported acute neurological deterioration in the setting of CM-I and acquired Chiari malformations. Although brainstem dysfunction has been documented in patients with CM-II and hydrocephalus or shunt malfunction, to the authors' knowledge only 1 report describing ventriculoperitoneal (VP) shunt malfunction causing neurological deterioration in a patient with CM-I exists. The authors report on their experience with the treatment of previously asymptomatic CM-I in 2 children who experienced quite different manifestations of acute neurological deterioration secondary to VP shunt malfunction. Presumably, VP shunt malfunction created a positive rostral pressure gradient across a stenotic foramen magnum, resulting in tetraparesis from foramen magnum syndrome in 1 patient and acute ataxia and cranial nerve deficits from syringobulbia in the other. Although urgent shunt revisions yielded partial recovery of neurological function in both patients, marked improvement occurred only after posterior fossa decompression.

Repeated Changes in Reported Sexual Orientation Identity Linked to Substance Use Behaviors in Youth

Science.gov (United States)

Ott, Miles Q.; Wypij, David; Corliss, Heather L.; Rosario, Margaret; Reisner, Sari L.; Gordon, Allegra R.; Austin, S. Bryn

2012-01-01

Purpose Previous studies have found that sexual minority (e.g., lesbian, gay, bisexual) adolescents are at higher risk of substance use than heterosexuals, but few have examined how changes in sexual orientation over time may relate to substance use. We examined the associations between change in sexual orientation identity and marijuana use, tobacco use, and binge drinking in U.S. youth. Methods Prospective data from 10,515 U.S. youth ages 12-27 years in a longitudinal cohort study were analyzed using sexual orientation identity mobility measure M (frequency of change from 0 [no change] to 1 [change at every wave]) in up to five waves of data. Generalized estimating equations were used to estimate substance use risk ratios and 95% confidence intervals; interactions by sex and age group were assessed. Results All substance use behaviors varied significantly by sexual orientation. Sexual minorities were at higher risk for all outcomes, excluding binge drinking in males, and mobility score was positively associated with substance use in most cases (p<.05). The association between mobility and substance use remained significant after adjusting for current sexual orientation and varied by sex and age for selected substance use behaviors. This association had a higher positive magnitude in females than males and in adolescents than young adults. Conclusions In both clinical and research settings it is important to assess history of sexual orientation changes. Changes in reported sexual orientation over time may be as important as current sexual orientation for understanding adolescent substance use risk. PMID:23298999

Sustainability reporting in public sector organisations: Exploring the relation between the reporting process and organisational change management for sustainability.

Science.gov (United States)

Domingues, Ana Rita; Lozano, Rodrigo; Ceulemans, Kim; Ramos, Tomás B

2017-05-01

Sustainability Reporting has become a key element in different organisations. Although there have been a number of academic publications discussing the adoption of sustainability reports in the public sector, their numbers have been quite low when compared to those focussing on corporate reports. Additionally, there has been little research on the link between sustainability reporting in Public Sector Organisations (PSOs) and Organisational Change Management for Sustainability (OCMS). This paper focuses on the contribution of sustainability reporting to OCMS. A survey was sent to all PSOs that have published at least one sustainability report based on the GRI guidelines. The study provides a critical analysis of the relation between sustainability reporting and OCMS in PSOs, including the drivers for reporting, the impacts on organisation change management, and the role of stakeholders in the process. Despite still lagging in sustainability reporting journey, PSOs are starting to use sustainability reporting as a communication tool, and this could drive organisational changes for sustainability. Copyright © 2017 Elsevier Ltd. All rights reserved.

12 CFR 250.180 - Reports of changes in control of management.

Science.gov (United States)

2010-01-01

... 12 Banks and Banking 3 2010-01-01 2010-01-01 false Reports of changes in control of management... FEDERAL RESERVE SYSTEM MISCELLANEOUS INTERPRETATIONS Interpretations § 250.180 Reports of changes in control of management. (a) Under a statute enacted September 12, 1964 (Pub. L. 88-593; 78 Stat. 940) all...

Important changes in medical x-ray imaging facility shielding design methodology. A brief summary of recommendations in NCRP Report No. 147

International Nuclear Information System (INIS)

Archer, Benjamin R.; Gray, Joel E.

2005-01-01

The recently published Report No. 147 of The National Council on Radiation Protection and Measurements entitled 'Structural shielding design for medical x-ray imaging facilities' provides an update of shielding recommendations for x rays used for medical imaging. The goal of this report is to ensure that the shielding in these facilities limits radiation exposures to employees and members of the public to acceptable levels. Board certified medical and health physicists, as defined in this report, are the 'qualified experts' who are competent to design radiation shielding for these facilities. As such, physicists must be aware of the new technical information and the changes from previous reports that Report No. 147 supersedes. In this article we summarize the new data, models and recommendations for the design of radiation barriers in medical imaging facilities that are presented in Report No. 147

Process cells dismantling of EUREX pant: previous activities

International Nuclear Information System (INIS)

Gili, M.

1998-01-01

In the '98-'99 period some process cells of the EUREX pant will be dismantled, in order to place there the liquid wastes conditioning plant 'CORA'. This report resumes the previous activities (plant rinsing campaigns and inactive Cell 014 dismantling), run in the past three years and the drawn experience [it

[Double mutant alleles in the EXT1 gene not previously reported in a teenager with hereditary multiple exostoses].

Science.gov (United States)

Cammarata-Scalisi, Francisco; Cozar, Mónica; Grinberg, Daniel; Balcells, Susana; Asteggiano, Carla G; Martínez-Domenech, Gustavo; Bracho, Ana; Sánchez, Yanira; Stock, Frances; Delgado-Luengo, Wilmer; Zara-Chirinos, Carmen; Chacín, José Antonio

2015-04-01

Hereditary forms of multiple exostoses, now called EXT1/EXT2-CDG within Congenital Disorders of Glycosylation, are the most common benign bone tumors in humans and clinical description consists of the formation of several cartilage-capped bone tumors, usually benign and localized in the juxta-epiphyseal region of long bones, although wide body dissemination in severe cases is not uncommon. Onset of the disease is variable ranging from 2-3 years up to 13-15 years with an estimated incidence ranging from 1/18,000 to 1/50,000 cases in European countries. We present a double mutant alleles in the EXT1 gene not previously reported in a teenager and her family with hereditary multiple exostoses.

USERS NEEDS: A PREMISE FOR CORPORATE REPORTING CHANGE

Directory of Open Access Journals (Sweden)

Farcas Teodora Viorica

2015-07-01

Full Text Available The topic of corporate reporting is very actual being subject of preoccupation of the main international regulatory and professional organisms in the accounting area. Hence, our study targets a priority research area. Its main objective is to discuss the concept of user needs and to emphasize how the needs of users of corporate financial reports have developed in time and how these needs are the main factors influencing the actual changes in the framework of the corporate reporting. In the nowadays society of knowledge, characterized by the variety and growing needs of corporate reports users, the regulatory organism are trying to respond. During time the concept of user of corporate reporting, referring here at financial reporting has changed from the owner of the business, to the manager and nowadays to a larger category of users. From the seven categories of users identified in 1975 by the Accounting Standard Steering Committee (investors, creditors, employees, the group of business partners, the state authority and the public, the most important seem to be the ones representing the capital providers. Analysing the latest IASB and the IIRC conceptual framework we could observe that both have a decision usefulness objective. Therefore, their main objective is to guide companies to make available reports that will help capital providers in the decision process. IR is considered to be a further step in the corporate reporting, therefore, by analysing it conceptual framework we observed how the needs also of the other categories of users are to be accomplished by using this type of reports. Also IR comes as a continuation/response of IASB framework, which recognizes its limits in the first paragraphs, saying that the financial information supplied by the companies in accordance with the framework is not sufficient and that the users’ needs to consult also other pertinent materials. Thus, the IR is composed from financial and non- financial

Technical-evaluation report on the proposed technical-specification changes on degraded grid-voltage protection for the Rancho Seco Nuclear Generating Plant (Docket No. 50-312)

International Nuclear Information System (INIS)

Selan, J.C.

1983-01-01

This Technical Evaluation Report is a revision and contains supplemental information to the Technical Evaluations documented in previous LLNL reports dated October 1980 (UCID-18690), November 10, 1981 (UCID-19113), and July 15, 1983 (UCID-19708). These reports encompass the NRC requirements on Degraded Grid Voltage Protection and Adequacy of Station Electric Distribution System Voltages. The evaluation finds that the proposed Technical Specification changes on the undervoltage/overvoltage trip setpoints and Limiting Conditions for Operation provide the required protection to the Class 1E Equipment from sustained abnormal voltages

Iodine-131 induced hepatotoxicity in previously healthy patients with Grave’s disease

Science.gov (United States)

2013-01-01

Objective To describe the association of the rare and serious complication of liver toxicity in previously healthy Grave’s disease (GD) patients after the treatment with radioactive iodine 131I (RAI). Case presentation We report the clinical, laboratory and pathologic findings of 2 cases of severe liver toxicity associated with the treatment with RAI in previously healthy patients with GD. Clinical examination and laboratory investigations excluded viral hepatitis, autoimmune hepatitis, granulomatous disease, primary biliary disease, extrahepatic biliary obstruction, and heart failure. Case 1: A previously healthy 52-years old man reportedly having a typical GD but following RAI treatment, concomitantly developed severe liver toxicity that required 1 week of treatment in hospital. Case 2: A previously healthy 34-years old woman is reported as having a typical GD but developed jaundice following RAI treatment that required several weeks of in hospital treatment in the hepato-biliary department. In both cases, the liver dysfunction resolved after intensive treatment with hepato-protective agents. In this report the therapeutic considerations as well as the pathogenetic possibilities are reviewed. Conclusion To the best of our knowledge, this is the first description of the association observed, which is rare but may be severe and should be considered in any case of thyrotoxicosis where a liver dysfunction develops after the treatment with radioactive iodine 131I. PMID:23497434

Varenicline in Autism: Theory and Case Report of Clinical and Biochemical Changes.

Science.gov (United States)

Mostafavi, Mojdeh; Hardy, Paul; Arnold, L Eugene

2016-11-01

To explore the potential benefits of varenicline (CHANTIX ® ), a highly specific partial agonist of neuronal α4β2 nicotinic acetylcholine receptors (nAChR), for autistic symptoms, and present resulting biochemical changes in light of dopamine-related genotype. The clinical and biochemical changes exhibited by a 19-year-old severely autistic man following the use of low-dose varenicline in an ABA experiment of nature, and his genotype, were extracted from chart review. Clinical outcome was measured by the Ohio Autism Clinical Impression Scale and 12 relevant urine and saliva metabolites were measured by Neuroscience Laboratory. With varenicline, this patient improved clinically and autonomic biochemical indicators in saliva and urine normalized, including dopamine, 3,4-dihydroxyphenylacetic acid (DOPAC), epinephrine, norepinephrine, taurine, and histamine levels. In addition, with varenicline, the dopamine D1 receptor (DRD1) antibody titer as well as the percent of baseline calmodulin-dependent protein kinase II (CaM KII) activity dropped significantly. When varenicline stopped, he deteriorated; when it was resumed, he again improved. Doses of 0.5, 1, and 2 mg daily were tried before settling on a dose of 1.5 mg daily. He has remained on varenicline for over a year with no noticeable side effects. This report is, to the best of our knowledge, only the second to demonstrate positive effects of varenicline in autism, the first to show it in a severe case, and the first to show normalization of biochemical parameters related to genotype. As with the previous report, these encouraging results warrant further controlled research before clinical recommendations can be made.

Bilateral orbital infarction and retinal detachment in a previously undiagnosed sickle cell hemoglobinopathy African child

Science.gov (United States)

Helen, Onakpoya Oluwatoyin; Ajite, K. O.; Oyelami, O. A.; Asaleye, C. M.; Adeoye, A. O.

2013-01-01

Bone infarction involving the orbit in sickle cell disease is not common. Bilateral orbital infarction in a previously undiagnosed sickle cell hemoglobinopathy has not been previously reported. In this report, we present a case of an 11-year-old previously undiagnosed sickle cell disease Nigerian girl with severe acute bilateral orbital infarction and retinal detachment to highlight that hemoglobinopathy induced orbital infarction should be considered in African children with acute onset proptosis with or without previous history of sickle cell hemoglobinopathy. PMID:23901183

A case report: mixed thrombus formation in a previously sutured right atrium.

Science.gov (United States)

Yunfei, Ling; Dongxu, Li; Shuhua, Luo; Yabo, Wang; San, Deep; Changping, Gan; Ke, Lin; Qi, An

2014-08-01

We describe the case of a 19-year-old Chinese woman who nine months prior underwent repair of an atrial septal defect and came to our hospital with a right atrial mass attached to the anterior wall of the right atrium on transthoracic echocardiography. Pathologic examination revealed the mass was a mixed-type thrombosis with some unusual organization, which previously was not described in literature.

Structural analysis of eight novel and 112 previously reported missense mutations in the interactive FXI mutation database reveals new insight on FXI deficiency.

Science.gov (United States)

Saunders, Rebecca E; Shiltagh, Nuha; Gomez, Keith; Mellars, Gillian; Cooper, Carolyn; Perry, David J; Tuddenham, Edward G; Perkins, Stephen J

2009-08-01

Factor XI (FXI) functions in blood coagulation. FXI is composed of four apple (Ap) domains and a serine protease (SP) domain. Deficiency of FXI leads to an injury-related bleeding disorder, which is remarkable for the lack of correlation between bleeding symptoms and FXI coagulant activity (FXI:C). The number of mutations previously reported in our interactive web database (http://www.FactorXI.org) is now significantly increased to 183 through our new patient studies and from literature surveys. Eight novel missense mutations give a total of 120 throughout the FXI gene (F11). The most abundant defects in FXI are revealed to be those from low-protein plasma levels (Type I: CRM-) that originate from protein misfolding, rather than from functional defects (Type II: CRM+). A total of 70 Ap missense mutations were analysed using a consensus Ap domain structure generated from the FXI dimer crystal structure. This showed that all parts of the Ap domain were affected. The 47 SP missense mutations were also distributed throughout the SP domain structure. The periphery of the Ap beta-sheet structure is sensitive to structural perturbation caused by residue changes throughout the Ap domain, yet this beta-sheet is crucial for FXI dimer formation. Residues located at the Ap4:Ap4 interface in the dimer are much less directly involved. We conclude that the abundance of Type I defects in FXI results from the sensitivity of the Ap domain folding to residue changes within this, and discuss how structural knowledge of the mutations improves our understanding of FXI deficiencies.

Previous induced abortion among young women seeking abortion-related care in Kenya: a cross-sectional analysis.

Science.gov (United States)

Kabiru, Caroline W; Ushie, Boniface A; Mutua, Michael M; Izugbara, Chimaraoke O

2016-05-14

Unsafe abortion is a leading cause of death among young women aged 10-24 years in sub-Saharan Africa. Although having multiple induced abortions may exacerbate the risk for poor health outcomes, there has been minimal research on young women in this region who have multiple induced abortions. The objective of this study was therefore to assess the prevalence and correlates of reporting a previous induced abortion among young females aged 12-24 years seeking abortion-related care in Kenya. We used data on 1,378 young women aged 12-24 years who presented for abortion-related care in 246 health facilities in a nationwide survey conducted in 2012. Socio-demographic characteristics, reproductive and clinical histories, and physical examination assessment data were collected from women during a one-month data collection period using an abortion case capture form. Nine percent (n = 98) of young women reported a previous induced abortion prior to the index pregnancy for which they were receiving care. Statistically significant differences by previous history of induced abortion were observed for area of residence, religion and occupation at bivariate level. Urban dwellers and unemployed/other young women were more likely to report a previous induced abortion. A greater proportion of young women reporting a previous induced abortion stated that they were using a contraceptive method at the time of the index pregnancy (47 %) compared with those reporting no previous induced abortion (23 %). Not surprisingly, a greater proportion of young women reporting a previous induced abortion (82 %) reported their index pregnancy as unintended (not wanted at all or mistimed) compared with women reporting no previous induced abortion (64 %). Our study results show that about one in every ten young women seeking abortion-related care in Kenya reports a previous induced abortion. Comprehensive post-abortion care services targeting young women are needed. In particular, post

Environmental effects of ozone depletion and its interactions with climate change: Progress report, 2016

Science.gov (United States)

When considering the effects of climate change, it has become clear that processes resulting in changes in stratospheric ozone are more complex than previously believed. As a result of this, human health and environmental issues will be longer-lasting and more regionally variable...

The long-term consequences of previous hyperthyroidism

DEFF Research Database (Denmark)

Hjelm Brandt Kristensen, Frans

2015-01-01

Thyroid hormones affect every cell in the human body, and the cardiovascular changes associated with increased levels of thyroid hormones are especially well described. As an example, short-term hyperthyroidism has positive chronotropic and inotropic effects on the heart, leading to a hyperdynamic...... with CVD, LD and DM both before and after the diagnosis of hyperthyroidism. Although the design used does not allow a stringent distinction between cause and effect, the findings indicate a possible direct association between hyperthyroidism and these morbidities, or vice versa....... vascular state. While it is biologically plausible that these changes may induce long-term consequences, the insight into morbidity as well as mortality in patients with previous hyperthyroidism is limited. The reasons for this are a combination of inadequately powered studies, varying definitions...

IPCC Fourth Assessment Report (AR4) Observed Climate Change Impacts Database

Data.gov (United States)

National Aeronautics and Space Administration — The Intergovernmental Panel on Climate Change (IPCC) Fourth Assessement Report (AR4) Observed Climate Change Impacts Database contains observed responses to climate...

2007 status of climate changes: synthesis report. Summary for policy-makers

International Nuclear Information System (INIS)

2007-01-01

This Synthesis Report is based on the assessment carried out by the three Working Groups of the Intergovernmental Panel on Climate Change (IPCC). It provides an integrated view of climate change as the final part of the IPCC's Fourth Assessment Report (AR4). Topic 1 summarises observed changes in climate and their effects on natural and human systems, regardless of their causes, while topic 2 assesses the causes of the observed changes. Topic 3 presents projections of future climate change and related impacts under different scenarios. Topic 4 discusses adaptation and mitigation options over the next few decades and their interactions with sustainable development. Topic 5 assesses the relationship between adaptation and mitigation on a more conceptual basis and takes a longer-term perspective. Topic 6 summarises the major robust findings and remaining key uncertainties in this assessment

The pathogenicity of genetic variants previously associated with left ventricular non-compaction

DEFF Research Database (Denmark)

Abbasi, Yeganeh; Jabbari, Javad; Jabbari, Reza

2016-01-01

BACKGROUND: Left ventricular non-compaction (LVNC) is a rare cardiomyopathy. Many genetic variants have been associated with LVNC. However, the number of the previous LVNC-associated variants that are common in the background population remains unknown. The aim of this study was to provide...... an updated list of previously reported LVNC-associated variants with biologic description and investigate the prevalence of LVNC variants in healthy general population to find false-positive LVNC-associated variants. METHODS AND RESULTS: The Human Gene Mutation Database and PubMed were systematically...... searched to identify all previously reported LVNC-associated variants. Thereafter, the Exome Sequencing Project (ESP) and the Exome Aggregation Consortium (ExAC), that both represent the background population, was searched for all variants. Four in silico prediction tools were assessed to determine...

Standardization for climate change. Approaches and perspectives. Final report

International Nuclear Information System (INIS)

Weterings, R.

1995-01-01

The results of a project, aimed at support of the environmental quality target for climate policy on a national level (Follow-up Memorandum Climatic Change of the Dutch government) and on an international level (elaboration of the UN Framework Convention on Climate Change). In order to generate ideas for standards of the climate policy a workshop was held on Environmental Quality and Climate. During the workshop standards of climatic change were highlighted from different points of view. Those views and perspectives are analyzed and the results are presented in this report. 4 figs., 31 refs

New climate change report turns up the heat on energy policymakers

Energy Technology Data Exchange (ETDEWEB)

Shepherd, John [nuclear 24, London (United Kingdom)

2014-12-15

Any doubts about the role of nuclear power in fighting the damaging effects of climate change should be dispelled once and for all by the latest report from the Intergovernmental Panel on Climate Change (IPCC). The key findings of the IPCC's so-called 'Synthesis Report', published in November 2014, said that if left unchecked, climate change ''will increase the likelihood of severe, pervasive and irreversible impacts for people and ecosystems''. The Synthesis Report, which brought together the findings of the IPCC's Fifth Assessment Report produced by more than 800 scientists and released over more than one year, noted that multiple mitigation pathways are available that could limit warming to below 2 C relative to pre-industrial levels, all of which would need substantial cuts in emissions reductions over the coming few decades and near-zero emissions of CO{sub 2} and other long-lived greenhouse gases (GHGs) by the end of the century. As 2014 draws to a close, perhaps those with the power to effect energy policy change will take time to reflect on the mounting evidence of what is good, and what is not good, in terms of balancing the world's energy needs with the planet's overall health.

Study of effects of climate change in the Great South East. Stage 1. PACA report - Part I: Context and study summary, Part II: Climate simulations, Part III: Impact sector sheets, General report. Prospective study of effects of climate change in the Great South East (phase 2) - Mission of study of inter-regional and European collaborations

International Nuclear Information System (INIS)

Kornmann, Francois; Guiran, Ghislaine; Sadoux, Emmanuel; Weill, Frederic; Benkhelifa, Fouzi

2008-01-01

After a presentation of study objectives and scope, a first report outlines the actuality of climate change, describes predicted climate changes for the PACA region in terms of warming and decrease of precipitations. Regional social-economic challenges and sector impacts are also briefly described. The second report presents the adopted climate simulation parameters, and discusses results obtained in terms of temperature and of precipitations by 2030, 2050 and 2080 for the whole Great South East region. The third part proposes sector sheets which contain discussions of effects of climate change on the water resource, on biodiversity, on forest, on agriculture, on human health, on tourism, on energy, on building and transports, on natural risks. The next document is based on the previous ones. It discusses and comments the outcome of the first phase, the present situation of the region in terms of territorial dynamics and effects of climate change, and indicators of climate change. It also draws lessons from the prospective study which resulted in three scenarios for which a strategic assessment is proposed

Fish quality – linking previous infections to the quality of consumers’ fillet

DEFF Research Database (Denmark)

The quality of the fish meat is dependent upon a wide range of biological and non-biological factors. In the present study it has been established that previous infections by Vibrio anguillarum in rainbow trout (Oncorhynchus mykiss) influence the quality of the fish meat (fillet) at slaughter more...... than after the fish have recovered from the infection. The texture of the fillet analysed by sensory analysis showed changes, which could be explained by previous tissue damage caused by the infection. These changes indicated formation of scars in affected tissue during the processes of tissue repair......, which gave rise to a more fibrous, tougher and flaky texture of the fillets....

National inventory report of greenhouse gas sources and sinks in Canada 1990-2004 : submission to the United Nations Framework Convention on Climate Change

Energy Technology Data Exchange (ETDEWEB)

Neitzert, F.; Collas, P.; Matin, A.; Jaques, A. (comps.) [Environment Canada, Gatineau, PQ (Canada). Greenhouse Gas Division

2006-04-15

As a member of the United Nations Framework Convention on Climate Change (UNFCCC), Canada must submit an annual national inventory of anthropogenic sources and sinks of greenhouses gases (GHGs) not included in the Montreal Protocol. Climate change refers to changes in long-term weather patterns caused by natural phenomena and human activities that alter the chemical composition of the atmosphere through the build up of GHGs that trap heat and reflect it back to the Earth's surface. Canada has been submitting a complete inventory annually for more than a decade, continuously improving the quality of GHG inventory and updating previous estimates to provide a consistent and comparable trend in emissions and removals of carbon dioxide, methane, nitrous oxide, sulphur hexafluoride, perfluorocarbons, and hydrofluorocarbons. The changes for 2004 include studies in upstream oil and oil refining industries; updates in Statistics Canada's underlying energy data; adoption of improved, country-specific methodologies and factors for agricultural soils nitrous oxide emissions; and, major revision of the estimation model for emissions from landfills. The general impact of these changes is that emission growth over the reporting period, previously reported to be 24.2 per cent, is now estimated to be 25.9 per cent. In terms of GHG emission trends in 2004, the total GHG emissions in Canada, expressed as carbon dioxide equivalent (CO{sub 2}e) were 758 Mt which represents a 0.6 per cent increase over the 2003 total and a 26.6 per cent increase over the 1990 total, and 34.6 per cent above the Kyoto target. The increase from 2003 to 2004 was small because of a reduced demand for heating fuel due to warmer weather, and greater emissions reductions from electricity production on the basis of increased nuclear availability and reduced coal generation. In 2004, emissions from most sectors such as industrial process, solvent, agriculture and waste were increased, but emissions from

Automated baseline change detection phase I. Final report

Energy Technology Data Exchange (ETDEWEB)

NONE

1995-12-01

The Automated Baseline Change Detection (ABCD) project is supported by the DOE Morgantown Energy Technology Center (METC) as part of its ER&WM cross-cutting technology program in robotics. Phase 1 of the Automated Baseline Change Detection project is summarized in this topical report. The primary objective of this project is to apply robotic and optical sensor technology to the operational inspection of mixed toxic and radioactive waste stored in barrels, using Automated Baseline Change Detection (ABCD), based on image subtraction. Absolute change detection is based on detecting any visible physical changes, regardless of cause, between a current inspection image of a barrel and an archived baseline image of the same barrel. Thus, in addition to rust, the ABCD system can also detect corrosion, leaks, dents, and bulges. The ABCD approach and method rely on precise camera positioning and repositioning relative to the barrel and on feature recognition in images. In support of this primary objective, there are secondary objectives to determine DOE operational inspection requirements and DOE system fielding requirements.

Automated baseline change detection phase I. Final report

International Nuclear Information System (INIS)

1995-12-01

The Automated Baseline Change Detection (ABCD) project is supported by the DOE Morgantown Energy Technology Center (METC) as part of its ER ampersand WM cross-cutting technology program in robotics. Phase 1 of the Automated Baseline Change Detection project is summarized in this topical report. The primary objective of this project is to apply robotic and optical sensor technology to the operational inspection of mixed toxic and radioactive waste stored in barrels, using Automated Baseline Change Detection (ABCD), based on image subtraction. Absolute change detection is based on detecting any visible physical changes, regardless of cause, between a current inspection image of a barrel and an archived baseline image of the same barrel. Thus, in addition to rust, the ABCD system can also detect corrosion, leaks, dents, and bulges. The ABCD approach and method rely on precise camera positioning and repositioning relative to the barrel and on feature recognition in images. In support of this primary objective, there are secondary objectives to determine DOE operational inspection requirements and DOE system fielding requirements

What does the new IPCC report say about climate change?

International Nuclear Information System (INIS)

Petit, Michel

2013-01-01

The author comments the contents of the latest IPCC report which has been published in September 2013. He gives an overview of climate understanding, comments and discusses the climate natural variations, the changes of atmosphere composition which appears to be notably related to human activities, the noticed climate change, the developments, use and results of climate models, the comparison of their results with recent observations, and climate changes which have been already noticed or foreseen for the 21. century. He finally evokes the perspective of an ineluctable climate change

New Zealand's Fourth National Communication under the United Nations Framework Convention on Climate Change. Including the Report on the Global Climate Observing System and the Report on Demonstrable Progress under the Kyoto Protocol

International Nuclear Information System (INIS)

2006-03-01

The New Zealand Government is committed to playing its part in the global response to climate change. This Fourth National Communication provides a snapshot of New Zealand's progress with implementing the United Nations Framework Convention on Climate Change (UNFCCC). This document covers the period from the submission of the Third National Communication in January 2002 through to the end of December 2005. This document also contains New Zealand's Report on the Global Climate Observing System and the Report on Demonstrable Progress under the Kyoto Protocol. New Zealand's response to climate change has evolved substantially since the Third National Communication was submitted. On 19 December 2002, New Zealand became the 101st nation to ratify the Kyoto Protocol. In 2002, the New Zealand Parliament passed the Climate Change Response Act. This Act established a New Zealand climate change registry and corresponding institutional arrangements in accordance with Kyoto Protocol requirements. Other achievements are detailed throughout this Fourth National Communication. When the Government introduced its climate change policy package in 2002, it anticipated there would be three reviews of the package not later than 2005, 2007 and 2010. The reviews would be necessary to monitor progress with emissions reductions, assess the effectiveness of policies, and confirm that New Zealand was positioned to meet its commitments. The first of these reviews was commissioned by the Government in mid-2005 and completed by November 2005. The review concluded that some elements of the Government's 2002 climate change policy package should be modified to better position New Zealand to respond to the longer-term challenges of climate change. A key outcome of the policy review was the announcement by the newly elected Government in December 2005 that the previously announced carbon tax would not proceed. In addition, a suite of future work programmes would be required to inform Government

Secondary recurrent miscarriage is associated with previous male birth.

LENUS (Irish Health Repository)

Ooi, Poh Veh

2012-01-31

Secondary recurrent miscarriage (RM) is defined as three or more consecutive pregnancy losses after delivery of a viable infant. Previous reports suggest that a firstborn male child is associated with less favourable subsequent reproductive potential, possibly due to maternal immunisation against male-specific minor histocompatibility antigens. In a retrospective cohort study of 85 cases of secondary RM we aimed to determine if secondary RM was associated with (i) gender of previous child, maternal age, or duration of miscarriage history, and (ii) increased risk of pregnancy complications. Fifty-three women (62.0%; 53\\/85) gave birth to a male child prior to RM compared to 32 (38.0%; 32\\/85) who gave birth to a female child (p=0.002). The majority (91.7%; 78\\/85) had uncomplicated, term deliveries and normal birth weight neonates, with one quarter of the women previously delivered by Caesarean section. All had routine RM investigations and 19.0% (16\\/85) had an abnormal result. Fifty-seven women conceived again and 33.3% (19\\/57) miscarried, but there was no significant difference in failure rates between those with a previous male or female child (13\\/32 vs. 6\\/25, p=0.2). When patients with abnormal results were excluded, or when women with only one previous child were considered, there was still no difference in these rates. A previous male birth may be associated with an increased risk of secondary RM but numbers preclude concluding whether this increases recurrence risk. The suggested association with previous male birth provides a basis for further investigations at a molecular level.

Secondary recurrent miscarriage is associated with previous male birth.

LENUS (Irish Health Repository)

Ooi, Poh Veh

2011-01-01

Secondary recurrent miscarriage (RM) is defined as three or more consecutive pregnancy losses after delivery of a viable infant. Previous reports suggest that a firstborn male child is associated with less favourable subsequent reproductive potential, possibly due to maternal immunisation against male-specific minor histocompatibility antigens. In a retrospective cohort study of 85 cases of secondary RM we aimed to determine if secondary RM was associated with (i) gender of previous child, maternal age, or duration of miscarriage history, and (ii) increased risk of pregnancy complications. Fifty-three women (62.0%; 53\\/85) gave birth to a male child prior to RM compared to 32 (38.0%; 32\\/85) who gave birth to a female child (p=0.002). The majority (91.7%; 78\\/85) had uncomplicated, term deliveries and normal birth weight neonates, with one quarter of the women previously delivered by Caesarean section. All had routine RM investigations and 19.0% (16\\/85) had an abnormal result. Fifty-seven women conceived again and 33.3% (19\\/57) miscarried, but there was no significant difference in failure rates between those with a previous male or female child (13\\/32 vs. 6\\/25, p=0.2). When patients with abnormal results were excluded, or when women with only one previous child were considered, there was still no difference in these rates. A previous male birth may be associated with an increased risk of secondary RM but numbers preclude concluding whether this increases recurrence risk. The suggested association with previous male birth provides a basis for further investigations at a molecular level.

Changes in Low Back Pain reporting over time in adult Danes

DEFF Research Database (Denmark)

Kjær, Per; Korsholm, Lars; Leboeuf-Yde, Charlotte

was to describe changes in low back pain (LBP) reporting over an eight-year period in a cohort of adult Danes. Methods: A cohort of 625 men and women, aged 40, was randomly sampled to be representative of the general population. Questions about LBP were asked at the age of 41, 45, and 48. Two definitions of LBP...... were investigated: “Trivial LBP” (any reported LBP during the past month) and “Non-trivial LBP” (reporting more than 30 days with LBP during the past year with consequences: sick leave, healthcare contacts or limitations in participation). Prevalence rates at the three different times were reported...... and the course of LBP was visualized. Results: The response rate was 66%, 56%, and 47%, respectively. The prevalence rates of different types of LBP did not change significantly across this eight-year period (trivial: 42%, 48%, 40%; non-trivial: 18%, 20%, 20%). Around 50% of those with LBP reported the same type...

ONERC Observatoire National sur les Effets du Rechauffement Climatique (National Observatory of Climate warming effects). Report to the Prime Minister and to Parliament. Climate changes and public health risks in France

International Nuclear Information System (INIS)

2010-01-01

After having recalled the climate change context and the activities of the ONERC (the French National Observatory of Climate Warming Effects) since its previous report, this report gathers several contributions by as many scientists. They propose analysis, comments and discussions on various topics: human diseases which might be influenced by climate change in France (heat waves and allergies, emergence of animal and human diseases, potential impacts of climate change on vector-borne diseases, infectious diseases in overseas territories, public health consequences), surveillance and health alert systems (infectious disease national surveillance and monitoring network, emergency response, satellite imagery, public health and risk management, lessons learned from the chikungunya pandemic), public health and risk management (overview of international works on the relationship between climate change and public health, public health consequences of climate change)

Prospective evaluation of patient-reported quality-of-life outcomes following SBRT ± cetuximab for locally-recurrent, previously-irradiated head and neck cancer

International Nuclear Information System (INIS)

Vargo, John A.; Heron, Dwight E.; Ferris, Robert L.; Rwigema, Jean-Claude M.; Wegner, Rodney E.; Kalash, Ronny; Ohr, James; Kubicek, Greg J.; Burton, Steven

2012-01-01

Purpose: Stereotactic body radiotherapy (SBRT) has emerged as a promising salvage strategy for unresectable, previously-irradiated recurrent squamous cell carcinomas of the head and neck (rSCCHN). Here-in, we report the first prospective evaluation of patient-reported quality-of-life (PR-QoL) following re-irradiation with SBRT ± cetuximab for rSCCHN. Materials and methods: From November 2004 to May 2011, 150 patients with unresectable, rSCCHN in a previously-irradiated field receiving >40 Gy were treated with SBRT to 40–50 Gy in 5 fractions ± concurrent cetuximab. PR-QoL was prospectively acquired using University of Washington Quality-of-Life Revised (UW-QoL-R). Results: Overall PR-QoL, health-related PR-QoL, and select domains commonly affected by re-irradiation progressively increase following an initial 1-month decline with statistically significant improvements noted in swallowing (p = 0.025), speech (p = 0.017), saliva (p = 0.041), activity (p = 0.032) and recreation (p = 0.039). Conclusions: Especially for patients surviving >1-year, improved tumor control associated with SBRT re-irradiation may ameliorate decreased PR-QoL resulting from rSCCHN. These improvements in PR-QoL transcend all measured domains in a validated PR-QoL assessment tool independent of age, use of cetuximab, tumor volume, and interval since prior irradiation.

Change of lifestyle habits - Motivation and ability reported by pregnant women in northern Sweden.

Science.gov (United States)

Lindqvist, Maria; Lindkvist, Marie; Eurenius, Eva; Persson, Margareta; Mogren, Ingrid

2017-10-01

Pregnant women are generally more motivated to change their lifestyle habits compared with non-pregnant women. However, the ability to change these habits depends on the motivation to change. This study describes pregnant women's self-reported motivation and ability to change lifestyle habits and their relation to body mass index (BMI), self-rated health, educational level and country of origin. This cross-sectional study combined data from the Maternal Health Care Register in Västerbotten (MHCR-VB) and the Salut Programme Register (Salut-R). Data were collected from 3,868 pregnant residents in Västerbotten County (northern Sweden) between 2011 and 2012. Chi-square test, two independent samples t-test and univariate and multivariate logistic regression were performed. Most of the pregnant women (61.3%) were satisfied with their self-reported lifestyle habits irrespective of BMI, self-rated health, educational level, and country of origin. Many reported that they wanted to increase their physical activity, improve their dietary habits, and reduce their weight. In general, they estimated their ability to change their lifestyle habits as equal to their motivation of change. Women who reported a large or very large motivation to change their lifestyle habits were characterized by higher BMI and higher educational level. Most of the participating pregnant women were satisfied with their lifestyle habits, although they reported being further motivated to change some of them. Health care professionals encountering fertile and pregnant women may have a unique opportunity to support and promote lifestyle changes, taking into account women's motivation for change. Future research should focus on factors that motivate pregnant women to change their lifestyle, explore barriers for change of lifestyle and how support best may be provided to pregnant women. In addition, studies on lifestyle and motivation for lifestyle change from non-Nordic countries are called for. Copyright

FASB's ASU 2011-7 changes financial statement reporting requirements.

Science.gov (United States)

Reinstein, Alan; Churyk, Natalie Tatiana

2012-02-01

FASB's new Accounting Standards Update 2011-07 will change how healthcare entities accumulate and report major portions of their financial statements, including patient revenues, net accounts receivables, and bad-debt expenses. Healthcare entities now must reclassify their provisions for bad debts associated with patient service revenue from an operating expense to a deduction from patient service revenue (net of contractual allowances and discounts). International Financial Reporting Standards do not require healthcare entities to comply with this new standard.

TU-CD-BRD-01: Making Incident Learning Practical and Useful: Challenges and Previous Experiences

International Nuclear Information System (INIS)

Ezzell, G.

2015-01-01

aside for audience members to contribute to the discussion. Learning Objectives: Learn how to promote the use of an incident learning system in a clinic. Learn how to convert “event reporting” into “incident learning”. See examples of practice changes that have come out of learning systems. Learn how the RO-ILS system can be used as a primary internal learning system. Learn how to create succinct, meaningful reports useful to outside readers. Gary Ezzell chairs the AAPM committee overseeing RO-ILS and has received an honorarium from ASTRO for working on the committee reviewing RO-ILS reports. Derek Brown is a director of http://TreatSafely.org . Brett Miller has previously received travel expenses and an honorarium from Varian. Phillip Beron has nothing to report

TU-CD-BRD-01: Making Incident Learning Practical and Useful: Challenges and Previous Experiences

Energy Technology Data Exchange (ETDEWEB)

Ezzell, G. [Mayo Clinic Arizona (United States)

2015-06-15

aside for audience members to contribute to the discussion. Learning Objectives: Learn how to promote the use of an incident learning system in a clinic. Learn how to convert “event reporting” into “incident learning”. See examples of practice changes that have come out of learning systems. Learn how the RO-ILS system can be used as a primary internal learning system. Learn how to create succinct, meaningful reports useful to outside readers. Gary Ezzell chairs the AAPM committee overseeing RO-ILS and has received an honorarium from ASTRO for working on the committee reviewing RO-ILS reports. Derek Brown is a director of http://TreatSafely.org . Brett Miller has previously received travel expenses and an honorarium from Varian. Phillip Beron has nothing to report.

Climate change at global and regional scale

International Nuclear Information System (INIS)

Dufresne, J.L.; Royer, J.F.

2008-01-01

In support of the Fourth Assessment Report of the Intergovernmental Panel on Climate Change (IPCC) that should appear in early 2007, modelling groups world-wide have performed a huge coordinated exercise of climate change runs for the 20. and 21. century. In this paper we present the results of the two french climate models, from CNRM and IPSL. In particular we emphasize the progress made since the previous IPCC report and we identify which results are comparable among models and which strongly differ. (authors)

Haemophilus influenzae type f meningitis in a previously healthy boy

DEFF Research Database (Denmark)

Ronit, Andreas; Berg, Ronan M G; Bruunsgaard, Helle

2013-01-01

Non-serotype b strains of Haemophilus influenzae are extremely rare causes of acute bacterial meningitis in immunocompetent individuals. We report a case of acute bacterial meningitis in a 14-year-old boy, who was previously healthy and had been immunised against H influenzae serotype b (Hib...

Changes in Reported Sexual Orientation Following US States Recognition of Same-Sex Couples

Science.gov (United States)

Corliss, Heather L.; Spiegelman, Donna; Williams, Kerry; Austin, S. Bryn

2016-01-01

Objectives. To compare changes in self-reported sexual orientation of women living in states with any recognition of same-sex relationships (e.g., hospital visitation, domestic partnerships) with those of women living in states without such recognition. Methods. We calculated the likelihood of women in the Nurses’ Health Study II (n = 69 790) changing their reported sexual orientation between 1995 and 2009. Results. We used data from the Nurses’ Health Study II and found that living in a state with same-sex relationship recognition was associated with changing one’s reported sexual orientation, particularly from heterosexual to sexual minority. Individuals who reported being heterosexual in 1995 were 30% more likely to report a minority orientation (i.e., bisexual or lesbian) in 2009 (risk ratio = 1.30; 95% confidence interval = 1.05, 1.61) if they lived in a state with any recognition of same-sex relationships compared with those who lived in a state without such recognition. Conclusions. Policies recognizing same-sex relationships may encourage women to report a sexual minority orientation. Future research is needed to clarify how other social and legal policies may affect sexual orientation self-reports. PMID:27736213

POEMS syndrome (polyneuropathy, organomegaly, endocrinopathy, multiple myeloma and skin changes) with cranial vault plasmocytoma and the role of surgery in its management: a case report

OpenAIRE

Plata Bello, Julio; Garcia-Marin, Victor

2013-01-01

Introduction POEMS syndrome (an acronym of polyneuropathy, organomegaly, endocrinopathy, multiple myeloma and skin changes) is a paraneoplastic disorder related to an underlying plasma cell dyscrasia. The development of such a syndrome is rare and its association with calvarial plasmocytoma is even less common, with only two previous reported cases. We describe, in detail, an unusual presentation of cranial plasmocytoma associated with POEMS syndrome and briefly discuss the possible role of s...

7 CFR 20.6 - Submission of reports.

Science.gov (United States)

2010-01-01

... specified in paragraph (k) of this section, a report by marketing year on the applicable forms contained in... quantity of outstanding export sales from the previous report by country of destination. (ii) Quantity of... cancelled and quantity of buyback contracts made during the week. (v) Changes in destination during the week...

Los Angeles County Metropolitan Transportation Authority climate change adaptation pilot project report.

Science.gov (United States)

2013-08-01

This Climate Change Adaptation Pilot Project Report details the project background of the recently-completed Los Angeles County : Metropolitan Transportation Authority (Metro) Transit Climate Change Adaptation Pilot Project as well as the various wor...

Subsequent childbirth after a previous traumatic birth.

Science.gov (United States)

Beck, Cheryl Tatano; Watson, Sue

2010-01-01

Nine percent of new mothers in the United States who participated in the Listening to Mothers II Postpartum Survey screened positive for meeting the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition criteria for posttraumatic stress disorder after childbirth. Women who have had a traumatic birth experience report fewer subsequent children and a longer length of time before their second baby. Childbirth-related posttraumatic stress disorder impacts couples' physical relationship, communication, conflict, emotions, and bonding with their children. The purpose of this study was to describe the meaning of women's experiences of a subsequent childbirth after a previous traumatic birth. Phenomenology was the research design used. An international sample of 35 women participated in this Internet study. Women were asked, "Please describe in as much detail as you can remember your subsequent pregnancy, labor, and delivery following your previous traumatic birth." Colaizzi's phenomenological data analysis approach was used to analyze the stories of the 35 women. Data analysis yielded four themes: (a) riding the turbulent wave of panic during pregnancy; (b) strategizing: attempts to reclaim their body and complete the journey to motherhood; (c) bringing reverence to the birthing process and empowering women; and (d) still elusive: the longed-for healing birth experience. Subsequent childbirth after a previous birth trauma has the potential to either heal or retraumatize women. During pregnancy, women need permission and encouragement to grieve their prior traumatic births to help remove the burden of their invisible pain.

2007 status of climate change: Mitigation of Climate Change. Contribution of Working Group III to the Fourth Assessment Report of the Intergovernmental Panel on Climate Change. Summary for Policy-makers

International Nuclear Information System (INIS)

Barker, T.; Bashmakov, I.; Bernstein, L.; Bogner, J.; Bosch, P.; Dave, R.; Davidson, O.; Fisher, B.; Grubb, M.; Gupta, S.; Halsnaes, K.; Heij, B.; Kahn Ribeiro, S.; Kobayashi, S.; Levine, M.; Martino, D.; Masera Cerutti, O.; Metz, B.; Meyer, L.; Nabuurs, G.J.; Najam, A.; Nakicenovic, N.; Holger Rogner, H.; Roy, J.; Sathaye, J.; Schock, R.; Shukla, P.; Sims, R.; Smith, P.; Swart, R.; Tirpak, D.; Urge-Vorsatz, D.; Dadi, Z.

2007-01-01

The Working Group III contribution to the IPCC Fourth Assessment Report (AR4) focuses on new literature on the scientific, technological, environmental, economic and social aspects of mitigation of climate change, published since the IPCC Third Assessment Report (TAR) and the Special Reports on CO 2 Capture and Storage (SRCCS) and on Safeguarding the Ozone Layer and the Global Climate System (SROC).The main aim of this summary report is to assess options for mitigating climate change. Several aspects link climate change with development issues. This report explores these links in detail, and illustrates where climate change and sustainable development are mutually reinforcing. Economic development needs, resource endowments and mitigative and adaptive capacities differ across regions. There is no one-size-fits-all approach to the climate change problem, and solutions need to be regionally differentiated to reflect different socio-economic conditions and, to a lesser extent, geographical differences. Although this report has a global focus, an attempt is made to differentiate the assessment of scientific and technical findings for the various regions. Given that mitigation options vary significantly between economic sectors, it was decided to use the economic sectors to organize the material on short- to medium-term mitigation options. Contrary to what was done in the Third Assessment Report, all relevant aspects of sectoral mitigation options, such as technology, cost, policies etc., are discussed together, to provide the user with a comprehensive discussion of the sectoral mitigation options. The report is organised into six sections after the introduction: - Greenhouse gas (GHG) emission trends; - Mitigation in the short and medium term, across different economic sectors (until 2030); - Mitigation in the long-term (beyond 2030); - Policies, measures and instruments to mitigate climate change; - Sustainable development and climate change mitigation; - Gaps in

77 FR 44113 - Airworthiness Directives; Gulfstream Aerospace LP (Type Certificate Previously Held by Israel...

Science.gov (United States)

2012-07-27

... Airworthiness Directives; Gulfstream Aerospace LP (Type Certificate Previously Held by Israel Aircraft... Aerospace LP (Type Certificate previously held by Israel Aircraft Industries, Ltd.) Model Gulfstream G150... to the manufacturer. This action was prompted by a report from the Civil Aviation Authority of Israel...

Determination of the Boltzmann constant with cylindrical acoustic gas thermometry: new and previous results combined

Science.gov (United States)

Feng, X. J.; Zhang, J. T.; Lin, H.; Gillis, K. A.; Mehl, J. B.; Moldover, M. R.; Zhang, K.; Duan, Y. N.

2017-10-01

We report a new determination of the Boltzmann constant k B using a cylindrical acoustic gas thermometer. We determined the length of the copper cavity from measurements of its microwave resonance frequencies. This contrasts with our previous work (Zhang et al 2011 Int. J. Thermophys. 32 1297, Lin et al 2013 Metrologia 50 417, Feng et al 2015 Metrologia 52 S343) that determined the length of a different cavity using two-color optical interferometry. In this new study, the half-widths of the acoustic resonances are closer to their theoretical values than in our previous work. Despite significant changes in resonator design and the way in which the cylinder length is determined, the value of k B is substantially unchanged. We combined this result with our four previous results to calculate a global weighted mean of our k B determinations. The calculation follows CODATA’s method (Mohr and Taylor 2000 Rev. Mod. Phys. 72 351) for obtaining the weighted mean value of k B that accounts for the correlations among the measured quantities in this work and in our four previous determinations of k B. The weighted mean {{\\boldsymbol{\\hat{k}}}{B}} is 1.380 6484(28)  ×  10-23 J K-1 with the relative standard uncertainty of 2.0  ×  10-6. The corresponding value of the universal gas constant is 8.314 459(17) J K-1 mol-1 with the relative standard uncertainty of 2.0  ×  10-6.

Do attitudes of families concerned influence features of children who claim to remember previous lives?

Science.gov (United States)

Pasricha, Satwant K

2011-01-01

Reported cases of nearly 2600 children (subjects) who claim to remember previous lives have been investigated in cultures with and without belief in reincarnation. The authenticity in most cases has been established. To study the influence of attitudes of parents of the subjects, families of the deceased person with whom they are identified and attention paid by others on the features of the cases. The study is based on field investigations. Data is derived from analysis of a larger series of an ongoing project. Information on initial and subsequent attitudes of subjects' mothers was available for 292 and 136 cases, respectively; attitudes of 227 families of deceased person (previous personality) with whom he is identified, and the extent of attention received from outsiders for 252 cases. Observations and interviews with multiple firsthand informants on both sides of the case as well as some neutral informants supplemented by examination of objective data were the chief methods of investigation. The initial attitude of mothers varied from encouragement (21%) to neutral or tolerance (51%) to discouragement (28%). However, it changed significantly from neutrality to taking measures to induce amnesia in their children for previous life memories due to various psychosocial pressures and prevalent beliefs. Families of the previous personalities, once convinced, showed complete acceptance in a majority of cases. Outside attention was received in 58% cases. The positive attitude of parents might facilitate expression of memories but subsequently attitudes of persons concerned do not seem to alter features of the cases.

18 CFR 35.42 - Change in status reporting requirement.

Science.gov (United States)

2010-04-01

... 18 Conservation of Power and Water Resources 1 2010-04-01 2010-04-01 false Change in status reporting requirement. 35.42 Section 35.42 Conservation of Power and Water Resources FEDERAL ENERGY... AND TARIFFS Wholesale Sales of Electric Energy, Capacity and Ancillary Services at Market-Based Rates...

Media Reporting of Practice-Changing Clinical Trials in Oncology: A North American Perspective.

Science.gov (United States)

Andrew, Peter; Vickers, Michael M; O'Connor, Stephen; Valdes, Mario; Tang, Patricia A

2016-03-01

Media reporting of clinical trials impacts patient-oncologist interactions. We sought to characterize the accuracy of media and Internet reporting of practice-changing clinical trials in oncology. The first media articles referencing 17 practice-changing clinical trials were collected from 4 media outlets: newspapers, cable news, cancer websites, and industry websites. Measured outcomes were media reporting score, social media score, and academic citation score. The media reporting score was a measure of completeness of information detailed in media articles as scored by a 15-point scoring instrument. The social media score represented the ubiquity of social media presence referencing 17 practice-changing clinical trials in cancer as determined by the American Society of Clinical Oncology in its annual report, entitled Clinical Cancer Advances 2012; social media score was calculated from Twitter, Facebook, and Google searches. The academic citation score comprised total citations from Google Scholar plus the Scopus database, which represented the academic impact per clinical cancer advance. From 170 media articles, 107 (63%) had sufficient data for analysis. Cohen's κ coefficient demonstrated reliability of the media reporting score instrument with a coefficient of determination of 94%. Per the media reporting score, information was most complete from industry, followed by cancer websites, newspapers, and cable news. The most commonly omitted items, in descending order, were study limitations, exclusion criteria, conflict of interest, and other. The social media score was weakly correlated with academic citation score. Media outlets appear to have set a low bar for coverage of many practice-changing advances in oncology, with reports of scientific breakthroughs often omitting basic study facts and cautions, which may mislead the public. The media should be encouraged to use a standardized reporting template and provide accessible references to original source

Cystic change in pulmonary tuberculosis in an immunocompetent adult: a case report

International Nuclear Information System (INIS)

Ko, Sung Min; Seo, Soo Ji; Choi, Won Il; Jeon, Young June

2008-01-01

Cystic change associated with pulmonary tuberculosis is rarely encountered, and few reports are available on the radiologic findings of pulmonary tuberculosis presenting as multiple cystic lesions associated with consolidation or bronchohematogenous nodules. The cystic lesions in our pulmonary tuberculosis patient occurred during steroid treatment without antituberculous chemotherapy and progressively increased in size, but subsequently became smaller after the initiation of antituberculous chemotherapy. Herein, we report the chest radiographic and computed tomographic findings of cystic change in pulmonary tuberculosis in an immunocompetent adult

National stakeholder workshops on climate change - 2002 : summary report

International Nuclear Information System (INIS)

2002-08-01

This summary report is based on 14 reports prepared following a series of 1 day climate change workshops held in 14 cities across Canada during the period of June 7 to 24, 2002. The input has been grouped into important themes that were highlighted during the workshops. The key messages focused on analysis and modelling, an overall approach to the Kyoto Protocol, targeted measures, domestic emissions trading, purchases of international emissions permits, preferred approach to the Kyoto Protocol, risks, and impacts and adaptations. The workshops were designed to provide participants with a better understanding of ways to respond to climate change and the Kyoto Protocol. They were also designed to obtain the views of the participants and options contained in the Federal Discussion Paper on Canada's Contribution to Addressing Climate Change, as well as the National Climate Change Process, and the national analysis conducted by the Analysis and Modelling Group (AMG). While many participants agreed that climate change is a real problem requiring attention, there were widely divergent views regarding the ratification of the Kyoto Protocol. Industry participants suggested alternative approaches that include a longer time frame, less restrictive targets and greater harmonization with the United States approach. The Alberta Plan gained some interest because it contained some of these characteristics, however, some argued that the Alberta Action Plan must meet the Kyoto target. There was good support for Targeted Measures, a mix of support and some concerns for Domestic Emissions Trading (DET), and opposition to the international purchases under the Clean Development Mechanisms and Joint Implementation. There was little support for Canada's request for Clean Energy Export Credits. The western provinces and Quebec were in favour of negotiated covenants with a regulatory backstop as an alternative to DET. 1 tab

The impact of a changed legislation on reporting of adverse drug reactions in Sweden, with focus on nurses' reporting.

Science.gov (United States)

Karlsson, Sofia A; Jacobsson, Ingela; Boman, Marit Danell; Hakkarainen, Katja M; Lövborg, Henrik; Hägg, Staffan; Jönsson, Anna K

2015-05-01

In March 2007, a legislative amendment was issued in Sweden compelling nurses to report all suspected adverse drug reactions (ADRs) to the national pharmacovigilance system. The aims of this study were to describe the status of ADR reporting, before and after the implementation of the legislative changes, and to describe the general characteristics of suspected ADRs reported by nurses. The Swedish pharmacovigilance system during the study period constituted six regional centres responsible for the handling of all spontaneous ADR reports within their region. In this study, we identified all individual ADR reports from 2005 and 2010, analysed in depth the ADR reports from two regional centres and collated information about the reporter and the nature of the reported ADR. From the two regional centres, a total of 898 and 1074 reports were submitted in 2005 and 2010 respectively. Nurses submitted 31% (275 reports) of the reports in 2005 and 24% (260 reports) in 2010. Nurses' reporting of serious ADRs was 3% (seven reports) in 2005 and 7% (17 reports) in 2010 with reporting of unlabelled ADRs at 4% (11 reports) in 2005 and 17% (45 reports) in 2010. Most of the serious and/or unlabelled reactions were related to vaccine administration (14 reports in 2005 and 36 reports in 2010). The overall ADR reporting by nurses did not appear to increase after the change in reporting legislation. The proportion of serious and/or unlabelled ADRs reported by nurses did however appear to increase during the same period. Taken together, our data suggests that further pro-active measures should be considered in order to involve nurses in the reporting of suspected ADRs.

New Record of Sillago sinica (Pisces: Sillaginidae in Korean Waters, and Re-identification of Sillago parvisquamis Previously Reported from Korea as S. sinica

Directory of Open Access Journals (Sweden)

Seung Eun Bae

2013-10-01

Full Text Available A single specimen of the genus Sillago, collected from Gwangyang, Korea, in May 2009, is characterized by XI first dorsal fin spines, 3 or 4 rows of melanophore pattern along the second dorsal fin membrane, and a darkish posterior margin of the caudal fin. Our specimen was identified as Sillago sinica reported as a new species; this identification is confirmed by mitochondrial DNA cytochrome oxidase subunit I sequences, which show that our specimen corresponds to S. sinica (d=0.000 and differs from the congeneric species Sillago parvisquamis (d=0.170. Comparisons of Korean specimens previously reported as S. parvisquamis with specimens of S. sinica show that the S. parvisquamis specimens are actually S. sinica. We propose the new Korean name “buk-bang-jeom-bo-ri-myeol” for S. sinica.

Climatic change impacts, adaptation and associated costs in France. Intermediate report. June 2008

International Nuclear Information System (INIS)

2008-01-01

This report aims at promoting the awareness of sector-based and land challenges of climate change in terms of impacts. It gives a wide overview of the present knowledge on sector-based vulnerabilities, and allows the identification of some paths for the alleviation of these vulnerabilities. After a discussion of objectives and context, of methodological choices (data, modalities to take impacts and adaptation into account, impact assessment approach) thematic woks are reported. They are dealing with health (population vulnerability to climate change with the example of 2006 heat wave), agriculture, forest and water, energy, tourism, natural risks and insurance, territories. For each of these topics, the reports discusses vulnerability aspects, the present knowledge about the impact of climate change, and identifies the core problems as well as studies which remain to be performed

The economics of climate change the stern report one year on

International Nuclear Information System (INIS)

Godard, O.

2007-01-01

In this article Olivier Godard, a specialist in environmental issues, looks back at the Stern Report on the economics of climate change, which was commissioned by the British government and published at the fall 2006. Having first recalled the general background to the report with regard to global warming and the lively debate that it generated, Godard sets it in perspective. He starts by describing the overall methodology and the main ideas in the Stern Report: a strong warning (that-without swift and decisive action to deal with the problem, the growth in human activities will cause serious, large-scale upheavals in this century and the next) coupled with an optimistic view (that nothing is inevitable provided that action is indeed swift, decisive and properly co-ordinated internationally, and the cost is relatively moderate). He puts figures to an evaluation of the damage to the environment suggested in various scenarios for the period up to 2200, as well as calculations showing that the feared climate change catastrophe is not unavoidable. He summarizes the policy recommendations offered in the Stern Report, emphasizing in passing that even the toughest policies cannot overcome all the problems. Godard goes on to discuss the key issue in the controversy that divides economists: what level to set the discount rate. He first describes the way this rate is calculated and then shows how the choices involved reflect above all the ethical trade-off with regard to the treatment of future generations and how the hypotheses underlying the economic evaluations of the impacts of climate change are far from being as scientifically objective as they claim to be. The Stern Report, he concludes, will at least have had the merit of bringing greater transparency in this regard and, despite certain limitations, it will have demonstrated the urgent need for co-ordinated action at global level to tackle climate change. (author)

PERSPECTIVE: Climate change: seeking balance in media reports

Science.gov (United States)

Huntingford, Chris; Fowler, David

2008-06-01

Boykoff and Mansfield (2008), in a recent paper in this journal, provide a detailed analysis of the representation of climate change in the UK tabloid newspapers. They conclude that the representation of this issue in these papers 'diverged from the scientific consensus that humans contribute to climate change'. That is, portrayal of climate change in tabloid newspapers contradicts the conclusions of the fourth Intergovernmental Panel on Climate Change (IPCC) assessment (IPCC 2007). Is it healthy to have the scientific consensus challenged so frequently? But should we worry about systematic misrepresentation of scientific consensus? We believe the answer to both of these questions is yes. To present regular updates on climate change issues in the popular press is important because the changes in behaviour needed to achieve substantial reductions in greenhouse gas emissions require a broad understanding of the basic facts. However, if the majority of readers receive misleading information, it will be difficult to achieve the level of public understanding necessary to make such reductions needed to avoid dangerous climate change (Schellnhuber et al 2006 and references therein). Boykoff and Mansfield (2008) identify a gulf in presentation of the scientific facts and their interpretation on the subject of 'global warming' in tabloid newspapers, when compared to the scientific consensus. What is really sobering is the huge circulation of these papers (see table 1 of Boykoff and Mansfield—many millions per day); even the most important 'landmark' research papers very rarely achieve five hundred plus citations. We find it heartening, therefore, that the area of climate change research does at least have the umbrella of the IPCC. This provides an additional channel through which current research associated with the effects of burning fossil fuels can be presented, and in our personal experience at least, we have found the non-tabloid UK newspapers to report accurately

Groin Problems in Male Soccer Players Are More Common Than Previously Reported

DEFF Research Database (Denmark)

Harøy, Joar; Clarsen, Ben; Thorborg, Kristian

2017-01-01

surveillance method developed to capture acute and overuse problems. STUDY DESIGN: Descriptive epidemiology study. METHODS: We registered groin problems during a 6-week period of match congestion using the Oslo Sports Trauma Research Center Overuse Injury Questionnaire. A total of 240 players from 15 teams......BACKGROUND: The majority of surveillance studies in soccer have used a time-loss injury definition, and many groin problems result from overuse, leading to gradually increasing pain and/or reduced performance without necessarily causing an absence from soccer training or match play. Thus......, the magnitude of groin problems in soccer has probably been underestimated in previous studies based on traditional injury surveillance methods. PURPOSE: To investigate the prevalence of groin problems among soccer players of both sexes and among male soccer players at different levels of play through a new...

Squamous cell carcinoma arising in previously burned or irradiated skin

International Nuclear Information System (INIS)

Edwards, M.J.; Hirsch, R.M.; Broadwater, J.R.; Netscher, D.T.; Ames, F.C.

1989-01-01

Squamous cell carcinoma (SCC) arising in previously burned or irradiated skin was reviewed in 66 patients treated between 1944 and 1986. Healing of the initial injury was complicated in 70% of patients. Mean interval from initial injury to diagnosis of SCC was 37 years. The overwhelming majority of patients presented with a chronic intractable ulcer in previously injured skin. The regional relapse rate after surgical excision was very high, 58% of all patients. Predominant patterns of recurrence were in local skin and regional lymph nodes (93% of recurrences). Survival rates at 5, 10, and 20 years were 52%, 34%, and 23%, respectively. Five-year survival rates in previously burned and irradiated patients were not significantly different (53% and 50%, respectively). This review, one of the largest reported series, better defines SCC arising in previously burned or irradiated skin as a locally aggressive disease that is distinct from SCC arising in sunlight-damaged skin. An increased awareness of the significance of chronic ulceration in scar tissue may allow earlier diagnosis. Regional disease control and survival depend on surgical resection of all known disease and may require radical lymph node dissection or amputation

Recurrent severe invasive pneumococcal disease in an adult with previously unknown hyposplenia

DEFF Research Database (Denmark)

Ballegaard, Vibe C; Schejbel, Lone; Hoffmann, Steen

2015-01-01

was found. Despite immunization against S. pneumoniae and measurement of what was interpreted as protective levels of serotype-specific IgG antibodies after vaccination, the patient suffered from a third episode of IPD. CONCLUSIONS: Individuals with predisposing medical conditions or a history of severe......BACKGROUND: The risk of life-threatening and invasive infections with encapsulated bacteria is increased in patients with hyposplenia or asplenia. We report a case of recurrent invasive pneumococcal meningitis in a woman with previous unknown hyposplenia. She was vaccinated after the first episode...... of meningitis and developed sufficient levels of pneumococcal antibodies. The pneumococcal strains isolated were serotype 7 F and 17 F. To our knowledge, there has been no previously reported case of recurrent invasive pneumococcal disease in a pneumococcal vaccinated adult with hyposplenia and apparently...

Changes in body mass index in long-term childhood cancer survivors

NARCIS (Netherlands)

van Santen, HM; Geskus, Ronald B; Raemaekers, Steven; van Trotsenburg, A S Paul; Vulsma, Thomas; van der Pal, Helena J H; Caron, Hubert N; Kremer, Leontien C M

2015-01-01

BACKGROUND: Previous studies have reported changes in the body mass index (BMI) with time in childhood cancer survivors (CCSs) during follow-up. The limitations of these studies include that they described only a subgroup of survivors or used questionnaires with self-reported heights and weights.

Impact of peer review audit on occupational health report quality.

Science.gov (United States)

Lalloo, D; Demou, E; Macdonald, E B

2015-08-01

In a previous report, we described the implementation of a formal process for peer review of occupational health (OH) reports and a method of assessment of the outcomes of this process. The initial audit identified that 27% of OH reports required modifications. To assess formally, following implementation of this process, if changes in practice had occurred, i.e. whether fewer deficiencies were being identified in reports. We repeated a prospective internal audit of all peer reviewed OH reports between September and November 2011. We used an abbreviated assessment form, based on questions 4-8 and 10-12 of the modified SAIL (Sheffield Assessment Instrument for Letters), with four possible outcomes: no action, no changes made to report following discussion with author, changes made without discussion with author and changes made following discussion with author. One hundred seventy-three reports by 10 clinicians were audited. The audit identified a 13% reduction in OH reports requiring modifications (from 27 to 14%) compared with the previous cycle. Where modifications were required, 8% of these were related to minor typographical, spelling and grammar errors and 6% were for more complex reasons. Implementation of this process also produced a reduction in clinical complaints about OH reports from customers, from three in the preceding year to none 2 years later. Peer review improved the standard of OH reports and was associated with a reduction in customer complaints about reports. © The Author 2015. Published by Oxford University Press on behalf of the Society of Occupational Medicine.

Hepatocellular Carcinoma Metastasis to the Orbit in a Coinfected HIV+ HBV+ Patient Previously Treated with Orthotopic Liver Transplantation: A Case Report

Directory of Open Access Journals (Sweden)

S. Guerriero

2011-01-01

Full Text Available Hepatocellular carcinoma rarely metastasizes to the orbit. We report a 45-year-old male, HBV+, HIV+, with a past history of a liver transplant for ELSD (end-stage liver disease with hepatocellular carcinoma and recurrent HCC, who presented with proptosis and diplopia of the left eye. CT scans of the head revealed a large, irregular mass in the left orbit causing superior and lateral destruction of the orbital bone. Biopsy specimens of the orbital tumor showed features of metastatic foci of hepatocellular carcinoma. Only 16 other cases of HCC metastasis to the orbit have been described in literature, and this is the first case in a previously transplanted HIV+, HBV+ patient.

The Conduct and Reporting of Child Health Research: An Analysis of Randomized Controlled Trials Published in 2012 and Evaluation of Change over 5 Years.

Science.gov (United States)

Gates, Allison; Hartling, Lisa; Vandermeer, Ben; Caldwell, Patrina; Contopoulos-Ioannidis, Despina G; Curtis, Sarah; Fernandes, Ricardo M; Klassen, Terry P; Williams, Katrina; Dyson, Michele P

2018-02-01

For child health randomized controlled trials (RCTs) published in 2012, we aimed to describe design and reporting characteristics and evaluate changes since 2007; assess the association between trial design and registration and risk of bias (RoB); and assess the association between RoB and effect size. For 300 RCTs, we extracted design and reporting characteristics and assessed RoB. We assessed 5-year changes in design and reporting (based on 300 RCTs we had previously analyzed) using the Fisher exact test. We tested for associations between design and reporting characteristics and overall RoB and registration using the Fisher exact, Cochran-Armitage, Kruskal-Wallis, and Jonckheere-Terpstra tests. We pooled effect sizes and tested for differences by RoB using the χ 2 test for subgroups in meta-analysis. The 2012 and 2007 RCTs differed with respect to many design and reporting characteristics. From 2007 to 2012, RoB did not change for random sequence generation and improved for allocation concealment (P < .001). Fewer 2012 RCTs were rated high overall RoB and more were rated unclear (P = .03). Only 7.3% of 2012 RCTs were rated low overall RoB. Trial registration doubled from 2007 to 2012 (23% to 46%) (P < .001) and was associated with lower RoB (P = .009). Effect size did not differ by RoB (P = .43) CONCLUSIONS: Random sequence generation and allocation concealment were not often reported, and selective reporting was prevalent. Measures to increase trialists' awareness and application of existing reporting guidance, and the prospective registration of RCTs is needed to improve the trustworthiness of findings from this field. Copyright © 2017 The Author(s). Published by Elsevier Inc. All rights reserved.

Elucidating the relationship between Sustainability Reporting and Organisational Change Management for Sustainability

NARCIS (Netherlands)

Lozano, Rodrigo|info:eu-repo/dai/nl/36412380X; Nummert, Benjamin; Ceulemans, Kim

2016-01-01

An increasing number of companies have, during the last two decades, engaged in reporting their sustainability efforts. Although Sustainability Reporting is considered to be a key driver for organisational change in companies; research into the link between these two processes has been limited. This

Nail changes secondary to docetaxel chemotherapy : a case report

Directory of Open Access Journals (Sweden)

Ghafoor Qamar

2008-01-01

Full Text Available Abstract Introduction Docetaxel is a chemotherapy agent used in the management of many neoplastic conditions. Various side effects are known. Nail changes are often under-recognised or attributed to other causes. Case presentation We report the case of a 66 year old gentleman who received docetaxel chemotherapy for non-small cell lung cancer. He had nail changes as a complication of the treatment. Conclusion Nail toxicity is a recognised side-effect of taxane chemotherapy agents and can often persist for many months after finishing the treatment. We would like to highlight this problem, so it can be considered as a differential diagnosis in the appropriate population.

Changes in body mass index in long-term childhood cancer survivors

NARCIS (Netherlands)

van Santen, Hanneke M.; Geskus, Ronald B.; Raemaekers, Steven; van Trotsenburg, A. S. Paul; Vulsma, Thomas; van der Pal, Helena J. H.; Caron, Hubert N.; Kremer, Leontien C. M.

2015-01-01

Previous studies have reported changes in the body mass index (BMI) with time in childhood cancer survivors (CCSs) during follow-up. The limitations of these studies include that they described only a subgroup of survivors or used questionnaires with self-reported heights and weights. The goal of

In Brief: Report details climate change effects on cultural sites

Science.gov (United States)

Zielinski, Sarah

2007-04-01

A new report from UNESCO (United Nations Educational, Scientific, and Cultural Organization) details how 26 World Heritage sites could be affected by coming climate changes. The 26 examples, which are meant to be representative of the range of threats to the 830 sites inscribed in the World Heritage List, are divided into five types: archaeological sites, glaciers, historic cities and settlements, marine biodiversity, and terrestrial biodiversity. Some of the examples include the Great Barrier Reef, which is expected to experience more frequent episodes of coral bleaching; Timbuktu in Mali, threatened by desertification; and the Chavín Archaeological Site in the Peruvian Central Andes, one of the earliest and best-known pre-Columbian sites, which could be affected by glacier melting and flooding. The report, ``Case Studies on Climate Change and World Heritage,'' is available at http://whc.unesco.org/documents/publi_climatechange.pdf

Applying & Publishing GRI framework in Transport Companies Rethink. Redesign. Rebuild. CSR Reporting and Climate Change

Directory of Open Access Journals (Sweden)

Lilian Soares Outtes Wanderley

2010-08-01

Full Text Available Corporations with systematic relationships to tourism are developing activities and publishing CSR reports applying the GRI framework (GRI, 2009. The contribution of tourism to climate change is estimated at between 5% and 12% and by 2050 the amount spent on the tourism sector will consume the entire carbon budget required to avoid dangerous climate change (Scott et al. 2009, UNWTO-UNEP-WMO 2008. This study defines the TC-8 group, a group of transport in tourism related companies, in order to answer the main questions:To what extent is climate change addressed in the CSR reports of transport companies? Climate change is mentioned and receives attention in all of the company reports analysed, however,overall the transport sector shows that in comparison to the GRI/KPMG (2007 survey, it under-performs. Are the companies just reporting direct emissions from production or also broader emissions from the use of the products? Half of these companies report emissions; some include direct and indirect emissions. Further actions can be mentioned such as, companies participating in forums discussing solutions to climate change, assuming shared responsibilities and employing measures such as reducing energy consumption by runningtheir own photovoltaic power unit or planning for a CO2 neutral operation by 2012.

Potential for erroneous interpretation of poisoning outcomes due to changes in National Poison Data System reporting.

Science.gov (United States)

Anderson, Bruce; Ke, Xuehua; Klein-Schwartz, Wendy

2010-08-01

In 2006, the annual report of poison centers in the United States changed the method of reporting profiles for generic substance categories from all exposures to single-substance exposures only. The objective of this study is to describe the potential impact of this reporting change on longitudinal analysis of outcomes. Generic substance categories with data available for all years of the study were manually extracted from Table 22 of the National Poison Data System (NPDS) annual reports for 2002-2007. For each generic substance category, the following data were extracted for each of the 6 years: total number of substance mentions (2002-2005) or single-substance exposures (2006-2007), reason (unintentional or intentional), pediatric exposures (children age average annual number of reported deaths by substance category decreased by 80.8%, from 2,229 in year 2002-2005 to 428 after the 2006 reporting change (p average annual number of reported major outcomes by substance category dropped by 76.0% (p average number of deaths and major effects by substance category decreased by about 50% from 394 and 4,639 per year during 2002-2005 to 198 deaths (p average rates of reported deaths (61.7 and 35.9%) and major effects (36.3 and 11.2%) for drug categories and nondrug categories, respectively (p change in 2006 will yield inaccurate results if the change in reporting methodology is not taken into account.

Understanding climate change adaptation and adaptive capacity: synthesis report

Energy Technology Data Exchange (ETDEWEB)

Patino, L. [Policy Research Initiative, Government of Canada, Ottawa, ON (Canada)

2010-09-15

In 2007, the Natural Resources Canada (NRCan) Climate Change Impacts and Adaptation Division (CCIAD) offered its support to research projects that were involved in understanding and improving adaptation and adaptive capacity and contributed to climate change decision-making and policy development in Canada. 20 research projects were commissioned by the CCIAD. With the collaboration of NRCan, the principal findings raised by the commissioned projects were synthesized by the Policy Research Initiative (PRI). Common themes and main messages are introduced in this synthesis report, and policy and program aspects that promote adaptive capacity to climate change in Canada are identified. Common themes and important messages emerging from the research projects, as well as the processes and barriers to adaptation and adaptive capacity identified in the commissioned projects, were discussed during a workshop held in Ottawa in 2009. Five main themes and four common barriers to adaptation were found. 25 refs.

"My math and me": Nursing students' previous experiences in learning mathematics.

Science.gov (United States)

Røykenes, Kari

2016-01-01

In this paper, 11 narratives about former experiences in learning of mathematics written by nursing students are thematically analyzed. Most students had a positive relationship with the subject in primary school, when they found mathematics fun and were able to master the subject. For some, a change occurred in the transition to lower secondary school. The reasons for this change was found in the subject (increased difficulty), the teachers (movement of teachers, numerous substitute teachers), the class environment and size (many pupils, noise), and the student him- or herself (silent and anonymous pupil). This change was also found in the transition from lower to higher secondary school. By contrast, some students had experienced changes that were positive, and their mathematics teacher was a significant factor in this positive change. The paper emphasizes the importance of previous experiences in learning mathematics to nursing students when learning about drug calculation. Copyright © 2015. Published by Elsevier Ltd.

Analysis of barriers and levers to the implementation of strategies of adaptation to climate changes - 2014-2015. The case of urban communities. Final report

International Nuclear Information System (INIS)

Simonet, Guillaume; Leseur, Alexia

2015-12-01

This is the final report of a research project (ABSTRACT-colurba) which aimed at exploring decision mechanisms and organisational dynamics underlying the elaboration of strategies of adaptation to climate changes by using results of a field study among ten previously selected French local communities. The objectives were to determine priority local social and economic challenges associated with expected impacts of climate changes, to identify economic, organisational and cognitive barriers and levers (at the State, representative or collectivity level) to an optimal implementation of measures of reduction of local vulnerabilities to climate changes, to identify possible or already used diagnosis tools for the assessment of costs and of priority investments, and to make comparisons with other referenced cases and to assess possibilities to bypass barriers thanks to a dialogue with stakeholders. After a presentation of the project (objectives, institutional context, guides and methodologies, scientific approach for data acquisition and analysis), the report presents and discusses the obtained results regarding the place given to adaptation in local policies (PCET, the French local climate-energy plans), representations of adaptation, the inclusion of adaptation in the agenda of public climatic action, tools to make adaptation operational, barriers and levers to action implementation

External cephalic version among women with a previous cesarean delivery: report on 36 cases and review of the literature.

Science.gov (United States)

Abenhaim, Haim A; Varin, Jocelyne; Boucher, Marc

2009-01-01

Whether or not women with a previous cesarean section should be considered for an external cephalic version remains unclear. In our study, we sought to examine the relationship between a history of previous cesarean section and outcomes of external cephalic version for pregnancies at 36 completed weeks of gestation or more. Data on obstetrical history and on external cephalic version outcomes was obtained from the C.H.U. Sainte-Justine External Cephalic Version Database. Baseline clinical characteristics were compared among women with and without a history of previous cesarean section. We used logistic regression analysis to evaluate the effect of previous cesarean section on success of external cephalic version while adjusting for parity, maternal body mass index, gestational age, estimated fetal weight, and amniotic fluid index. Over a 15-year period, 1425 external cephalic versions were attempted of which 36 (2.5%) were performed on women with a previous cesarean section. Although women with a history of previous cesarean section were more likely to be older and para >2 (38.93% vs. 15.0%), there were no difference in gestational age, estimated fetal weight, and amniotic fluid index. Women with a prior cesarean section had a success rate similar to women without [50.0% vs. 51.6%, adjusted OR: 1.31 (0.48-3.59)]. Women with a previous cesarean section who undergo an external cephalic version have similar success rates than do women without. Concern about procedural success in women with a previous cesarean section is unwarranted and should not deter attempting an external cephalic version.

The Emissions Gap Report 2014

DEFF Research Database (Denmark)

Farrell, Timothy Clifford

This fifth Emissions Gap report has a different focus from previous years. While it updates the 2020 emissions gap analysis, it gives particular attention to the implications of the global carbon dioxide emissions budget for staying within the 2 °C limit beyond 2020. It does so because countries...... are giving increasing attention to where they need to be in 2025, 2030 and beyond. Furthermore, this year’s update of the report benefits from the findings on the emissions budget from the latest series of Intergovernmental Panel on Climate Change (IPCC) reports...

Change in Reported Lyme Disease Incidence in the Northeast and Upper Midwest, 1991-2014

Science.gov (United States)

This indicator shows how reported Lyme disease incidence has changed by state since 1991, based on the number of new cases per 100,000 people. The total change has been estimated from the average annual rate of change in each state. This map is limited to the 14 states where Lyme disease is most common, where annual rates are consistently above 10 cases per 100,000. Connecticut, New York, and Rhode Island had too much year-to-year variation in reporting practices to allow trend calculation. For more information: www.epa.gov/climatechange/science/indicators

GATEWAY Report Brief: SSL Demonstration: Long-Term Evaluation of Indoor Field Performance

Energy Technology Data Exchange (ETDEWEB)

None, None

2017-02-28

Report brief summarizing a GATEWAY program evaluation of the long-term performance characteristics (chromaticity change, maintained illuminance, and operations and maintenance) of LED lighting systems in four field installations previously documented in separate DOE GATEWAY reports.

Climate Change and Development Framings: A Comparative Analysis of the Human Development Report 2007/8 an the World Development Report 2010

NARCIS (Netherlands)

D.R. Gasper (Des); A.V. Portocarrero (Ana Victoria); A. Lera St. Clair

2011-01-01

textabstractThe Human Development Report 2007/8 (HDR) and the World Development Report 2010 (WDR) are both devoted to the connections between climate change and development. The reports provide very different perspectives on where the key challenges reside. Their policy proposals are also different,

LHC Report: Production and small angles

CERN Multimedia

Jan Uythoven for the LHC team

2012-01-01

The last two weeks have seen steady luminosity production. The total luminosity of ATLAS and CMS exceeded 19 fb-1, while LHCb reached 1.8 fb-1 and ALICE, 6 pb-1.   As reported in previous LHC reports, the continuous running with large beam intensities is resulting in beam-induced heating of certain elements, such as the synchrotron light monitor (BSRT), the ALFA detector and the injection kicker magnets. These first two elements had shown a sudden increase in temperature in the previous weeks - but only for the components that are on the counter-clockwise rotating beam. By making slight changes to the radiofrequency parameters, which affect the bunch length, the power spectrum of the beam was changed. This significantly reduced the observed heating of the BSRT and the ALFA detector. Another improvement was recently made to the measurement process of the number of transverse oscillations of the beam in one turn, known as the “betatron tune”. The frequency of the betatron tune ...

Methods for interpreting change over time in patient-reported outcome measures.

Science.gov (United States)

Wyrwich, K W; Norquist, J M; Lenderking, W R; Acaster, S

2013-04-01

Interpretation guidelines are needed for patient-reported outcome (PRO) measures' change scores to evaluate efficacy of an intervention and to communicate PRO results to regulators, patients, physicians, and providers. The 2009 Food and Drug Administration (FDA) Guidance for Industry Patient-Reported Outcomes (PRO) Measures: Use in Medical Product Development to Support Labeling Claims (hereafter referred to as the final FDA PRO Guidance) provides some recommendations for the interpretation of change in PRO scores as evidence of treatment efficacy. This article reviews the evolution of the methods and the terminology used to describe and aid in the communication of meaningful PRO change score thresholds. Anchor- and distribution-based methods have played important roles, and the FDA has recently stressed the importance of cross-sectional patient global assessments of concept as anchor-based methods for estimation of the responder definition, which describes an individual-level treatment benefit. The final FDA PRO Guidance proposes the cumulative distribution function (CDF) of responses as a useful method to depict the effect of treatments across the study population. While CDFs serve an important role, they should not be a replacement for the careful investigation of a PRO's relevant responder definition using anchor-based methods and providing stakeholders with a relevant threshold for the interpretation of change over time.

Speech and Communication Changes Reported by People with Parkinson's Disease.

Science.gov (United States)

Schalling, Ellika; Johansson, Kerstin; Hartelius, Lena

2017-01-01

Changes in communicative functions are common in Parkinson's disease (PD), but there are only limited data provided by individuals with PD on how these changes are perceived, what their consequences are, and what type of intervention is provided. To present self-reported information about speech and communication, the impact on communicative participation, and the amount and type of speech-language pathology services received by people with PD. Respondents with PD recruited via the Swedish Parkinson's Disease Society filled out a questionnaire accessed via a Web link or provided in a paper version. Of 188 respondents, 92.5% reported at least one symptom related to communication; the most common symptoms were weak voice, word-finding difficulties, imprecise articulation, and getting off topic in conversation. The speech and communication problems resulted in restricted communicative participation for between a quarter and a third of the respondents, and their speech caused embarrassment sometimes or more often to more than half. Forty-five percent of the respondents had received speech-language pathology services. Most respondents reported both speech and language symptoms, and many experienced restricted communicative participation. Access to speech-language pathology services is still inadequate. Services should also address cognitive/linguistic aspects to meet the needs of people with PD. © 2018 S. Karger AG, Basel.

Evaluation of inventory change report (ICR) in 2008/2009 - 2012/2013 in MBA.RI-B

International Nuclear Information System (INIS)

Agustinus Suprijanto; Suratno; Sigit Pramana

2013-01-01

Evaluation has been performed for Inventory Change Report (ICR) in 2008/2009 - 2012/2013 in MBA.RI-B (MBA = Material Balance Area) (RI-B = Center for Accelerator and Material Process Technology). The evaluation performed on the inventory change report of nuclear material document. Changes in inventories occur when there is acceptance or shipment of nuclear materials outside nuclear facilities. Successive reports changes in inventory of nuclear material in 2008/2009 comprised 3 sheets ICR document numbers (153, 154 and 155), in 2009/2010 comprised 1 sheet ICR document number (159), in 2010/2011 comprised 3 sheets ICR document numbers (164, 165 and 166), and in 2012/2013 comprised 2 sheets ICR document numbers (175 and 176). From these data report changes in inventory of nuclear material can be concluded that in MBA.RI-B has been the displacement of nuclear material activities includes receipt of nuclear material from other nuclear facilities and shipments of nuclear materials out of facilities for research and development includes receipt 4 times from RI-E and 1 times from RI-A and 3 times shipment to RI-E. (author)

12 CFR 250.181 - Reports of change in control of bank management incident to a merger.

Science.gov (United States)

2010-01-01

... 12 Banks and Banking 3 2010-01-01 2010-01-01 false Reports of change in control of bank management... change in control of bank management incident to a merger. (a) A State member bank has inquired whether Pub. L. 88-593 (78 Stat. 940) requires reports of change in control of bank management in situations...

75 FR 76260 - Conforming Changes to Applicant Submission Requirements; Implementing Federal Financial Report...

Science.gov (United States)

2010-12-08

... HUD regulations to reference the new governmentwide Federal Financial Report (FFR) approved by the... task of filing required financial reports. Similarly, CCR registration has been required of applicants...] RIN 2501-AD50 Conforming Changes to Applicant Submission Requirements; Implementing Federal Financial...

The prevalence of previous self-harm amongst self-poisoning patients in Sri Lanka

DEFF Research Database (Denmark)

Mohamed, Fahim; Perera, Aravinda; Wijayaweera, Kusal

2011-01-01

BACKGROUND: One of the most important components of suicide prevention strategies is to target people who repeat self-harm as they are a high risk group. However, there is some evidence that the incidence of repeat self-harm is lower in Asia than in the West. The objective of this study...... was to investigate the prevalence of previous self-harm among a consecutive series of self-harm patients presenting to hospitals in rural Sri Lanka. METHOD: Six hundred and ninety-eight self-poisoning patients presenting to medical wards at two hospitals in Sri Lanka were interviewed about their previous episodes...... of self-harm. RESULTS: Sixty-one (8.7%, 95% CI 6.7-11%) patients reported at least one previous episode of self-harm [37 (10.7%) male, 24 (6.8%) female]; only 19 (2.7%, 95% CI 1.6-4.2%) patients had made more than one previous attempt. CONCLUSION: The low prevalence of previous self-harm is consistent...

Climate change adaptation in the Canadian energy sector : workshop report

International Nuclear Information System (INIS)

2009-01-01

This workshop on climate change adaptation in the Canadian energy sector was conducted in order to develop a climate change work plan for the Council of Energy Ministers (CEM) as well as to develop awareness and dialogue within Canada's energy sector. Industry members and government officials identified findings from recent assessment reports on climate change adaptation and discussed ways in which the international oil and gas industry is currently adapting its operations and technologies to ensure continuing safety and risk mitigation. The use of hydrological models to forecast the potential impacts of climate change was discussed, and the drivers of climate change adaptation were reviewed. A total of 26 topics were identified, 13 of which were prioritized for group discussions based on their impact and urgency. The following 5 topics were finally identified as top priority topics: (1) climate change adaptation science, (2) co-ordinated local, provincial, national, and international policies, (3) information sharing and knowledge transfer, (4) aging infrastructure and increasing demand, and (5) market mechanisms for adaptation. Four presentations were given during the initial portion of the workshop. 4 tabs., 1 fig

Matched cohort study of external cephalic version in women with previous cesarean delivery.

Science.gov (United States)

Keepanasseril, Anish; Anand, Keerthana; Soundara Raghavan, Subrahmanian

2017-07-01

To evaluate the efficacy and safety of external cephalic version (ECV) among women with previous cesarean delivery. A retrospective study was conducted using data for women with previous cesarean delivery and breech presentation who underwent ECV at or after 36 weeks of pregnancy during 2011-2016. For every case, two multiparous women without previous cesarean delivery who underwent ECV and were matched for age and pregnancy duration were included. Characteristics and outcomes were compared between groups. ECV was successful for 32 (84.2%) of 38 women with previous cesarean delivery and 62 (81.6%) in the control group (P=0.728). Multivariate regression analysis confirmed that previous cesarean was not associated with ECV success (odds ratio 1.89, 95% confidence interval 0.19-18.47; P=0.244). Successful vaginal delivery after successful ECV was reported for 19 (59.4%) women in the previous cesarean delivery group and 52 (83.9%) in the control group (P<0.001). No ECV-associated complications occurred in women with previous cesarean delivery. To avoid a repeat cesarean delivery, ECV can be offered to women with breech presentation and previous cesarean delivery who are otherwise eligible for a trial of labor. © 2017 International Federation of Gynecology and Obstetrics.

Effects of Climate Change on Aquatic Invasive Species and Implications for Management and Research (Final Report)

Science.gov (United States)

EPA announced the availability of the final report, Effects of Climate Change on Aquatic Invasive Species and Implications for Management and Research . This report reviews available literature on climate-change effects on aquatic invasive species (AIS) and examines sta...

A projected decrease in lightning under climate change

Science.gov (United States)

Finney, Declan L.; Doherty, Ruth M.; Wild, Oliver; Stevenson, David S.; MacKenzie, Ian A.; Blyth, Alan M.

2018-03-01

Lightning strongly influences atmospheric chemistry1-3, and impacts the frequency of natural wildfires4. Most previous studies project an increase in global lightning with climate change over the coming century1,5-7, but these typically use parameterizations of lightning that neglect cloud ice fluxes, a component generally considered to be fundamental to thunderstorm charging8. As such, the response of lightning to climate change is uncertain. Here, we compare lightning projections for 2100 using two parameterizations: the widely used cloud-top height (CTH) approach9, and a new upward cloud ice flux (IFLUX) approach10 that overcomes previous limitations. In contrast to the previously reported global increase in lightning based on CTH, we find a 15% decrease in total lightning flash rate with IFLUX in 2100 under a strong global warming scenario. Differences are largest in the tropics, where most lightning occurs, with implications for the estimation of future changes in tropospheric ozone and methane, as well as differences in their radiative forcings. These results suggest that lightning schemes more closely related to cloud ice and microphysical processes are needed to robustly estimate future changes in lightning and atmospheric composition.

Laparoscopy After Previous Laparotomy

Directory of Open Access Journals (Sweden)

Zulfo Godinjak

2006-11-01

Full Text Available Following the abdominal surgery, extensive adhesions often occur and they can cause difficulties during laparoscopic operations. However, previous laparotomy is not considered to be a contraindication for laparoscopy. The aim of this study is to present that an insertion of Veres needle in the region of umbilicus is a safe method for creating a pneumoperitoneum for laparoscopic operations after previous laparotomy. In the last three years, we have performed 144 laparoscopic operations in patients that previously underwent one or two laparotomies. Pathology of digestive system, genital organs, Cesarean Section or abdominal war injuries were the most common causes of previouslaparotomy. During those operations or during entering into abdominal cavity we have not experienced any complications, while in 7 patients we performed conversion to laparotomy following the diagnostic laparoscopy. In all patients an insertion of Veres needle and trocar insertion in the umbilical region was performed, namely a technique of closed laparoscopy. Not even in one patient adhesions in the region of umbilicus were found, and no abdominal organs were injured.

High-Grade Leiomyosarcoma Arising in a Previously Replanted Limb

Directory of Open Access Journals (Sweden)

Tiffany J. Pan

2015-01-01

Full Text Available Sarcoma development has been associated with genetics, irradiation, viral infections, and immunodeficiency. Reports of sarcomas arising in the setting of prior trauma, as in burn scars or fracture sites, are rare. We report a case of a leiomyosarcoma arising in an arm that had previously been replanted at the level of the elbow joint following traumatic amputation when the patient was eight years old. He presented twenty-four years later with a 10.8 cm mass in the replanted arm located on the volar forearm. The tumor was completely resected and pathology examination showed a high-grade, subfascial spindle cell sarcoma diagnosed as a grade 3 leiomyosarcoma with stage pT2bNxMx. The patient underwent treatment with brachytherapy, reconstruction with a free flap, and subsequently chemotherapy. To the best of our knowledge, this is the first case report of leiomyosarcoma developing in a replanted extremity. Development of leiomyosarcoma in this case could be related to revascularization, scar formation, or chronic injury after replantation. The patient remains healthy without signs of recurrence at three-year follow-up.

Pulmonary Aspergillosis in a Previously Healthy 13-Year-Old Boy

Directory of Open Access Journals (Sweden)

Jonathan H. Rayment

2016-01-01

Full Text Available Chronic granulomatous disease (CGD is a rare, polygenic primary immunodeficiency. In this case report, we describe a previously healthy 13-year-old boy who presented with multifocal pulmonary aspergillosis and was subsequently diagnosed with an autosomal recessive form of chronic granulomatous disease. CGD has a variable natural history and age of presentation and should be considered when investigating a patient with recurrent or severe infections with catalase-positive organisms.

Changes in clinical and hotel expenditures following publication of the nursing home compare report card.

Science.gov (United States)

Mukamel, Dana B; Spector, William D; Zinn, Jacqueline; Weimer, David L; Ahn, Richard

2010-10-01

Nursing Home Compare first published clinical quality measures at the end of 2002. It is a quality report card that for the first time offers consumers easily accessible information about the clinical quality of nursing homes. It led to changes in consumers' demand, increasing the relative importance of clinical versus hotel aspects of quality in their search and choice of a nursing home. To examine the hypothesis that nursing homes responding to these changes in demand shifted the balance of resources from hotel to clinical activities. The study included 10,022 free-standing nursing homes nationwide during 2001 to 2006. RESEARCH DESIGN AND DATA: A retrospective multivariate statistical analysis of trends in the ratio of clinical to hotel expenditures, using Medicare cost reports, Minimum Data Set and Online Survey, Certification and Reporting data, controlling for changes in residents' acuity and facility fixed effects. Inference is based on robust standard errors. The ratio of clinical to hotel expenditures averaged 1.78. It increased significantly (P hotel expenditures following publication of the report card suggests that nursing homes responded as expected to the changes in the elasticity of demand with respect to clinical quality brought about by the public reporting of clinical quality measures. The response was stronger among nursing homes facing stronger incentives.

Disseminated peritoneal leiomyomatosis with malignant change, in a male

DEFF Research Database (Denmark)

Lausen, I; Jensen, O J; Andersen, E

1990-01-01

Disseminated peritoneal leiomyomatosis (DPL) is a rare disorder, characterized by the occurrence of multiple leiomyomas scattered throughout the peritoneal cavity. Until this report DPL had been observed only in women and there is only one previous case with malignant change. A case of DPL...

Case Report: A Rare Case Report of Frontal Lobe Syndrome

Directory of Open Access Journals (Sweden)

Morteza Nouri- Khajavi

2003-04-01

Full Text Available The frontal lobe syndrome is a permanent personality change disorder with characteristic clinical pictures, which followed by frontal lobes damage. Clinical picture include: Affective instability, recurrent aggressive behavior, impaired social judgment, apathy and undifferentiating or suspiciousness and paranoid ideations. According DSM-IV classification frontal lobe syndrome named personality change due to head trauma on Axis I. Herein we report a case of 46 years-old man, who has developed behavioral disturbances following head trauma, about 10 years ago. Main clinical figures in this case are apathy, avolition and, undifferentiating. Clinical pictures are constant during these 10 years. The diagnostic approach has been based on patient’s problems history which, has taken from his family, mental status examination, Neurological examination, Brain imaging and Neuropsychological assessments which related to frontal lobes function. Because of rarity & neglection due to mysterious function of frontal lobes, and also considering that personality change from previous level is prominent figure of this syndrome and also brain imaging findings, which compatible with clinical findings, with this aim, we have reported this case.

Change Best.Task 2.1. National Report on the Energy Efficiency Service Business in Italy

International Nuclear Information System (INIS)

Sabbatucci, N.; Labanca, N.

2009-05-01

The aim of the Change Best project is to promote the development of an energy efficiency service (EES) market and to give good practice examples of changes in energy service business, strategies, and supportive policies and measures in the course of the implementation of Directive 2006/32/EC on Energy End-Use Efficiency and Energy Services. This report addresses Task 2.1: National Report on the Energy Efficiency Service Business in Italy. More information can be found on the website of Change Best at www.changebest.eu.

Dissociation in decision bias mechanism between probabilistic information and previous decision

Directory of Open Access Journals (Sweden)

Yoshiyuki eKaneko

2015-05-01

Full Text Available Target detection performance is known to be influenced by events in the previous trials. It has not been clear, however, whether this bias effect is due to the previous sensory stimulus, motor response, or decision. Also it remains open whether or not the previous trial effect emerges via the same mechanism as the effect of knowledge about the target probability. In the present study, we asked normal human subjects to make a decision about the presence or absence of a visual target. We presented a pre-cue indicating the target probability before the stimulus, and also a decision-response mapping cue after the stimulus so as to tease apart the effect of decision from that of motor response. We found that the target detection performance was significantly affected by the probability cue in the current trial and also by the decision in the previous trial. While the information about the target probability modulated the decision criteria, the previous decision modulated the sensitivity to target-relevant sensory signals (d-prime. Using functional magnetic resonance imaging, we also found that activation in the left intraparietal sulcus was decreased when the probability cue indicated a high probability of the target. By contrast, activation in the right inferior frontal gyrus was increased when the subjects made a target-present decision in the previous trial, but this change was observed specifically when the target was present in the current trial. Activation in these regions was associated with individual-difference in the decision computation parameters. We argue that the previous decision biases the target detection performance by modulating the processing of target-selective information, and this mechanism is distinct from modulation of decision criteria due to expectation of a target.

Dissociation in decision bias mechanism between probabilistic information and previous decision

Science.gov (United States)

Kaneko, Yoshiyuki; Sakai, Katsuyuki

2015-01-01

Target detection performance is known to be influenced by events in the previous trials. It has not been clear, however, whether this bias effect is due to the previous sensory stimulus, motor response, or decision. Also it remains open whether or not the previous trial effect emerges via the same mechanism as the effect of knowledge about the target probability. In the present study, we asked normal human subjects to make a decision about the presence or absence of a visual target. We presented a pre-cue indicating the target probability before the stimulus, and also a decision-response mapping cue after the stimulus so as to tease apart the effect of decision from that of motor response. We found that the target detection performance was significantly affected by the probability cue in the current trial and also by the decision in the previous trial. While the information about the target probability modulated the decision criteria, the previous decision modulated the sensitivity to target-relevant sensory signals (d-prime). Using functional magnetic resonance imaging (fMRI), we also found that activation in the left intraparietal sulcus (IPS) was decreased when the probability cue indicated a high probability of the target. By contrast, activation in the right inferior frontal gyrus (IFG) was increased when the subjects made a target-present decision in the previous trial, but this change was observed specifically when the target was present in the current trial. Activation in these regions was associated with individual-difference in the decision computation parameters. We argue that the previous decision biases the target detection performance by modulating the processing of target-selective information, and this mechanism is distinct from modulation of decision criteria due to expectation of a target. PMID:25999844

Minimal-change nephropathy and malignant thymoma.

Science.gov (United States)

Varsano, S; Bruderman, I; Bernheim, J L; Rathaus, M; Griffel, B

1980-05-01

A 56-year-old man had fever, precordial pain, and a mediastinal mass. The mass disappeared two months later and the patient remained asymptomatic for 2 1/2 years. At that time a full-blown nephrotic syndrome developed, with minimal-change glomerulopathy. The chest x-ray film showed the reappearance of a giant mediastinal mass. On biopsy of the mass, malignant thymoma was diagnosed. Association between minimal-change disease and Hodgkin's disease is well known, while the association with malignant thymoma has not been previously reported. The relationship between malignant thymoma and minimal-change disease is discussed, and a possible pathogenic mechanism involving cell-mediated immunity is proposed.

[Metatropic dysplasia in a girl with c.1811_1812delinsAT mutation in exon 11 of the TRPV4 gene not previously reported].

Science.gov (United States)

Cammarata-Scalisi, Francisco; Matysiak-Scholze, Uta; Heinze, Jessica; Barrera, Albaro; Lacruz-Rengel, María Angelina; Bracho, Ana; Guerrero, Yudith

2015-01-01

Metatropic dysplasia is a skeletal disorder with clinical heterogeneity, characterized by craniofacial dysmorphy including frontal bossing and midface hypoplasia, short trunk,progressive kyphoscoliosis and shortened limbs. The TRPV4 gene is located on 12q24.11, coding a cation channel with nonselective permeability to calcium; it is expressed and involved in many physiological processes through responses to different stimuli. Over 50 mutations in TRPV4 have been described. We present a seven months old girl with heterozygous mutation c.1811_1812delinsAT; p.I604N in intron 11 not previously reported in the TRPV4 gene and with clinical findings compatible with metatropic dysplasia.

Denmark's National Inventory Reports. Submitted under the United Nations framework convention on climate change

International Nuclear Information System (INIS)

Boll Illerup, J.; Lyck, E.; Winther, M.; Rasmussen, E.

2000-01-01

This report is Denmark's National Inventory Report reported to the Conference of the Parties under the United Nations Framework Convention on Climate Change (UNFCCC) due by 15 April 2000. The report contains information on Denmark's inventories for all years from 1990 to 1998 for CO 2 , CH 4 , N 2 O, NO x , CO, NMVOC, SO 2 , HFCs, PFCs and SF. (au)

Change in Reported Lyme Disease Incidence in the Northeast and Upper Midwest, 1991-2014

Data.gov (United States)

U.S. Environmental Protection Agency — This indicator shows how reported Lyme disease incidence has changed by state since 1991, based on the number of new cases per 100,000 people. The total change has...

Twenty-second report. Energy - the changing climate

International Nuclear Information System (INIS)

Blundell, Tom

2000-06-01

This comprehensive report examines the global context in Part 1 with chapters on the radical challenge; the causes and effects of climate change; possible preventive measures; and prospects for an effective global response. Part II focuses on the United Kingdom's response with chapters on the UK's present situation and policies; reducing energy use in the manufacturing industry, commercial and public services, households, and transport sectors; alternatives to fossil fuels such as renewable sources; patterns of energy supply and use; possible UK energy balances in the year 2050; and the adoption of a long-term strategy. Key recommendations are given, and illustrative energy balances for the UK in 2050, and technical issues relating to carbon resources and removal are discussed in the appendices

Progress report on the varying temperature experiment

Energy Technology Data Exchange (ETDEWEB)

Qualls, A.L.; Hurst, M.T.; Raby, D.G. [Oak Ridge National Lab., TN (United States)] [and others

1997-08-01

A capsule has been designed that permits four specimen sets to be irradiated in an RB* location in the High Flux Isotope reactor (HFIR) with distinct temperature histories. During the reporting period critical component prototyping was completed. The results have lead to some design and operational changes from that previously reported. The primary design changes are (1) compression seals in the specimen holes of the beryllium holders, and (2) oxide-dispersion strengthened aluminum alloy (DISPAL) specimen sleeves in all holders. Details of the capsule design are presented in the previous issue of this publication. Four, axially displaced temperature zones are independently controlled. Holder temperatures are monitored by thermocouples and controlled by a combination of adjustable temperature control gas mixtures and auxiliary heaters. The high temperature holders are located in the center of the experimental region, which is centered on the reactor mid-plane, and the low temperature holders are located at the ends of the experimental region.

Progress report on the varying temperature experiment

International Nuclear Information System (INIS)

Qualls, A.L.; Hurst, M.T.; Raby, D.G.

1997-01-01

A capsule has been designed that permits four specimen sets to be irradiated in an RB* location in the High Flux Isotope reactor (HFIR) with distinct temperature histories. During the reporting period critical component prototyping was completed. The results have lead to some design and operational changes from that previously reported. The primary design changes are (1) compression seals in the specimen holes of the beryllium holders, and (2) oxide-dispersion strengthened aluminum alloy (DISPAL) specimen sleeves in all holders. Details of the capsule design are presented in the previous issue of this publication. Four, axially displaced temperature zones are independently controlled. Holder temperatures are monitored by thermocouples and controlled by a combination of adjustable temperature control gas mixtures and auxiliary heaters. The high temperature holders are located in the center of the experimental region, which is centered on the reactor mid-plane, and the low temperature holders are located at the ends of the experimental region

Changes in work affect in response to lunchtime walking in previously physically inactive employees: A randomized trial.

Science.gov (United States)

Thøgersen-Ntoumani, C; Loughren, E A; Kinnafick, F-E; Taylor, I M; Duda, J L; Fox, K R

2015-12-01

Physical activity may regulate affective experiences at work, but controlled studies are needed and there has been a reliance on retrospective accounts of experience. The purpose of the present study was to examine the effect of lunchtime walks on momentary work affect at the individual and group levels. Physically inactive employees (N = 56; M age = 47.68; 92.86% female) from a large university in the UK were randomized to immediate treatment or delayed treatment (DT). The DT participants completed both a control and intervention period. During the intervention period, participants partook in three weekly 30-min lunchtime group-led walks for 10 weeks. They completed twice daily affective reports at work (morning and afternoon) using mobile phones on two randomly chosen days per week. Multilevel modeling was used to analyze the data. Lunchtime walks improved enthusiasm, relaxation, and nervousness at work, although the pattern of results differed depending on whether between-group or within-person analyses were conducted. The intervention was effective in changing some affective states and may have broader implications for public health and workplace performance. © 2015 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Changes in human parechovirus profiles in hospitalized children with acute gastroenteritis after a three-year interval in Lanzhou, China.

Directory of Open Access Journals (Sweden)

Ying Guo

Full Text Available The changing profile of infection over time for Human Parechoviruses (HPeVs is not well known and no detailed study has been reported to date in China. This investigation on HPeV infection in hospitalized children in Lanzhou, China revealed variations in epidemiological characteristics after a three-year interval. To assess the changes that had occurred, epidemiological and clinical characteristics of HPeVs were characterized and compared with previously reported data by our group. A comparable positivity rate (25.3%, 73/289 was revealed after the three-year interval with the majority of the infected children (95.9%, 70/73 being younger than two years of age. While a temporal change in the seasonal distribution was noted in the current study, HPeVs were more frequently detected during July to November compared to September to December in the previous study. Changes in HPeV genotypes patterns, a temporal change in the prevalence of HPeV1, a younger susceptible age to HPeV3 compared with HPeV1 and a tendency of older children to be infected with HPeV4 are in contrast to our previous report. HPeV2, a rarely reported genotype, was identified for the first time in China. In addition, an exclusive trinucleotide (GAT insertion in the HPeV4 nucleotide sequence was identified. However, the profiles of co-infection with other enteric related viruses were similar to our previous findings. In summary, these data suggest temporal variation in the seasonal distribution of HPeV and changing patterns of HPeV genotypes over time in the study region.

Upon Further Review: V. An Examination of Previous Lightcurve Analysis from the Palmer Divide Observatory

Science.gov (United States)

Warner, Brian D.

2011-01-01

Updated results are given for nine asteroids previously reported from the Palmer Divide Observatory (PDO). The original images were re-measured to obtain new data sets using the latest version of MPO Canopus photometry software, analysis tools, and revised techniques for linking multiple observing runs covering several days to several weeks. Results that were previously not reported or were moderately different were found for 1659 Punkajarju, 1719 Jens, 1987 Kaplan, 2105 Gudy, 2961 Katsurahama, 3285 Ruth Wolfe, 3447 Burckhalter, 7816 Hanoi, and (34817) 2000 SE116. This is one in a series of papers that will examine results obtained during the initial years of the asteroid lightcurve program at PDO.

Global and regional climate change: new evidences between two IPCC reports

Energy Technology Data Exchange (ETDEWEB)

Mika, J. [Eszterhazy Karoly College, Budapest (Hungary). Dept. of Geography

2011-07-01

The climate of our planet has never been constant, but the recent changes are by two orders of magnitude faster than the natural changes since the appearance of anthropogenic effects. The discernable global warming started in the 19th century and after speeding up in the 20th century, it has reached about 0.8 K. This fact and the realization of the likely reasons for the changes, plus rapid development of computer technology have resulted in systematic investigations of climate science. The Intergovernmental Panel on Climate Change (IPCC) finalized its Fourth Assessment Report in 2007. The present paper suveys some recent moments of global and regional climate change issued after the Report. Even the economic crisis was not strong enough to deflect the anthropogenic greenhouse gas forcing for more than one year. It tends to develop at the upper edge of the IPCC (2007) projection band of uncertainties. The part of the emitted carbon dioxide remaining in the atmosphere is increasing due to weakening of both the biospheric- and the oceanic sinks of this greenhouse gas. The new radiation balance estimations must admit the imbalance between the atmosphere and the oceans indicating the fact that the greenhouse warming definitely takes place. The year 2010 became most likely the warmest one on the global temperature record. The sea-level rise also follows the most rapid track among the foreseen scenarios. In the meantime modelling effort to better estimate regional features of the changes also develop in their full strength. The ENSEMBLES Project ended in December 2009 and published a lot of maps with 25 km model resolution. These results, however, do not show convergence in the estimations for many regions, including Central Europe.

Initial results of CyberKnife treatment for recurrent previously irradiated head and neck cancer

International Nuclear Information System (INIS)

Himei, Kengo; Katsui, Kuniaki; Yoshida, Atsushi

2003-01-01

The purpose of this study was to evaluate the efficacy of CyberKnife for recurrent previously irradiated head and neck cancer. Thirty-one patients with recurrent previously irradiated head and neck cancer were treated with a CyberKnife from July 1999 to March 2002 at Okayama Kyokuto Hospital were retrospectively studied. The accumulated dose was 28-80 Gy (median 60 Gy). The interval between CyberKnife treatment and previous radiotherapy was 0.4-429.5 months (median 16.3 months). Primary lesions were nasopharynx: 7, maxillary sinus: 6, tongue: 5, ethmoid sinus: 3, and others: 1. The pathology was squamous cell carcinoma: 25, adenoid cystic carcinoma: 4, and others: 2. Symptoms were pain: 8, and nasal bleeding: 2. The prescribed dose was 15.0-40.3 Gy (median 32.3 Gy) as for the marginal dose. The response rate (complete response (CR)+partial response (PR)) and local control rate (CR+PR+no change (NC)) was 74% and 94% respectively. Pain disappeared for 4 cases, relief was obtained for 4 cases and no change for 2 cases and nasal bleeding disappeared for 2 cases for an improvement of symptoms. An adverse effects were observed as mucositis in 5 cases and neck swelling in one case. Prognosis of recurrent previously irradiated head and neck cancer was estimated as poor. Our early experience shows that CyberKnife is expected to be feasible treatment for recurrent previously irradiated head and neck cancer, and for the reduction adverse effects and maintenance of useful quality of life (QOL) for patients. (author)

France's adaptation to climate change - Report to the Prime Minister and Parliament

International Nuclear Information System (INIS)

Galliot, Michel; Reysset, Bertrand; Bourcier, Vincent; Mondon, Sylvain; Omarjee, Younous; Allain, Maelle; Croguennec, Stephanie; Degeorges, Patrick; Durrleman, Colas; Perrier, Veronique; Begon, Helene; Benezeth, Isabelle; Lemaitre-Curri, Elen; Chauvin, Xavier; Clerc, Pierre-Francois; Chesneau, Anne-Laure; De Smedt, Sylvie; Dehault, Valerie; Loquet, Maryline; Poffet, Laetitia; Delalande, Daniel; Leuxe, Andre; Pochet, Arila; Richon, Jean-Luc; Schaefferer, Frederic

2012-01-01

The first part of this report presents the different aspects of the French national plan for adaptation to climate change: adaptation principles, national strategy, plan preparation, plan content, plan governance. It also comments the present uncertain context, the mobilization in Europe, and climate scenarios for France for the 21. century. A second part proposes a set of sheet presenting the various actions: transverse actions and actions in different fields (health, water, biodiversity, natural risks, agriculture, forest, fishing, tourism, energy and industry, transport infrastructures and services, urban planning and built environment, information, education and training, research, financing and insurance, coasts, mountain, European and international action, governance). A third part reports the content of a round table which discussed ten years (2001-2011) of struggle against climate change

The first description of severe anemia associated with acute kidney injury and adult minimal change disease: a case report

Directory of Open Access Journals (Sweden)

Qian Yimei

2009-01-01

Full Text Available Abstract Introduction Acute kidney injury in the setting of adult minimal change disease is associated with proteinuria, hypertension and hyperlipidemia but anemia is usually absent. Renal biopsies exhibit foot process effacement as well as tubular interstitial inflammation, acute tubular necrosis or intratubular obstruction. We recently managed a patient with unique clinical and pathological features of minimal change disease, who presented with severe anemia and acute kidney injury, an association not previously reported in the literature. Case presentation A 60-year-old Indian-American woman with a history of hypertension and diabetes mellitus for 10 years presented with progressive oliguria over 2 days. Laboratory data revealed severe hyperkalemia, azotemia, heavy proteinuria and progressively worsening anemia. Urine eosinophils were not seen. Emergent hemodialysis, erythropoietin and blood transfusion were initiated. Serologic tests for hepatitis B, hepatitis C, anti-nuclear antibodies, anti-glomerular basement membrane antibodies and anti-neutrophil cytoplasmic antibodies were negative. Complement levels (C3, C4 and CH50 were normal. Renal biopsy unexpectedly displayed 100% foot process effacement. A 24-hour urine collection detected 6.38 g of protein. Proteinuria and anemia resolved during six weeks of steroid therapy. Renal function recovered completely. No signs of relapse were observed at 8-month follow-up. Conclusion Adult minimal change disease should be considered when a patient presents with proteinuria and severe acute kidney injury even when accompanied by severe anemia. This report adds to a growing body of literature suggesting that in addition to steroid therapy, prompt initiation of erythropoietin therapy may facilitate full recovery of renal function in acute kidney injury.

Changes seen in the environment report from Uusimaa Regional Environment Centre

International Nuclear Information System (INIS)

Enckell, E.; Airola, H.; Tornivaara-Ruikka, R.; Villa, L.; Salasto, R.

2002-05-01

This publication describes the environmental changes and the influencing factors occurring within the administrative regions of the Uusimaa Regional Environment Centre. The quality of the environment can be judged as satisfying in regards to both the mental and physical health of humans. Areas have a steady trend of a relatively high growth in population density, while the efficiency of land use in new settlements is low. Traffic and the travel distances are on the rise. A considerable part of the population lives in areas where the noise standards are violated, despite control measures. Waste management, water distribution and sewage networks are under continuous development. In regards to the nature, the situation in some parts is of great concern. The manifold of the nature, cultural landscapes and culturally valuable buildings and sites are threatened. The living space of flora and fauna is continuing to decrease and change. The risks caused by human activities in groundwater areas are increasing. For these reasons the implementation of protection programs is important. Emissions from point sources to the water and air have significantly decreased. Yet, the impacts of air quality deprivation can still be seen in some cities and in the vicinity of some industrial sites. The eutrophication have essentially changed the ecology and fishstocks; however, the water quality has improved in many places. Regarding the above issues, as well as some other topics, included in the report are 16 theme maps 66 pictures. However, the report states that the monitoring and reporting of the environmental quality should be improved. (orig.)

76 FR 36472 - Mandatory Reporting of Greenhouse Gases; Changes to Provisions for Electronics Manufacturing...

Science.gov (United States)

2011-06-22

... Mandatory Reporting of Greenhouse Gases; Changes to Provisions for Electronics Manufacturing (Subpart I) To... proposing changes to the calculation and monitoring provisions in the Electronics Manufacturing portion... Category Examples of affected Category NAICS facilities Electronics Manufacturing......... 334111...

Transgender Transitioning and Change of Self-Reported Sexual Orientation

OpenAIRE

Auer, M.; Fuss, J.; Höhne, N.; Stalla, G.; Sievers, C.

2014-01-01

Objective Sexual orientation is usually considered to be determined in early life and stable in the course of adulthood. In contrast, some transgender individuals report a change in sexual orientation. A common reason for this phenomenon is not known. Methods We included 115 transsexual persons (70 male-to-female “MtF” and 45 female-to-male “FtM”) patients from our endocrine outpatient clinic, who completed a questionnaire, retrospectively evaluating the history of their gender transition pha...

Delivering organisational adaptation through legislative mechanisms: Evidence from the Adaptation Reporting Power (Climate Change Act 2008).

Science.gov (United States)

Jude, S R; Drew, G H; Pollard, S J T; Rocks, S A; Jenkinson, K; Lamb, R

2017-01-01

There is increasing recognition that organisations, particularly in key infrastructure sectors, are potentially vulnerable to climate change and extreme weather events, and require organisational responses to ensure they are resilient and adaptive. However, detailed evidence of how adaptation is facilitated, implemented and reported, particularly through legislative mechanisms is lacking. The United Kingdom Climate Change Act (2008), introduced the Adaptation Reporting Power, enabling the Government to direct so-called reporting authorities to report their climate change risks and adaptation plans. We describe the authors' unique role and experience supporting the Department for Environment, Food and Rural Affairs (Defra) during the Adaptation Reporting Power's first round. An evaluation framework, used to review the adaptation reports, is presented alongside evidence on how the process provides new insights into adaptation activities and triggered organisational change in 78% of reporting authorities, including the embedding of climate risk and adaptation issues. The role of legislative mechanisms and risk-based approaches in driving and delivering adaptation is discussed alongside future research needs, including the development of organisational maturity models to determine resilient and well adapting organisations. The Adaptation Reporting Power process provides a basis for similar initiatives in other countries, although a clear engagement strategy to ensure buy-in to the process and research on its long-term legacy, including the potential merits of voluntary approaches, is required. Copyright © 2016 The Authors. Published by Elsevier B.V. All rights reserved.

Underestimation of Severity of Previous Whiplash Injuries

Science.gov (United States)

Naqui, SZH; Lovell, SJ; Lovell, ME

2008-01-01

INTRODUCTION We noted a report that more significant symptoms may be expressed after second whiplash injuries by a suggested cumulative effect, including degeneration. We wondered if patients were underestimating the severity of their earlier injury. PATIENTS AND METHODS We studied recent medicolegal reports, to assess subjects with a second whiplash injury. They had been asked whether their earlier injury was worse, the same or lesser in severity. RESULTS From the study cohort, 101 patients (87%) felt that they had fully recovered from their first injury and 15 (13%) had not. Seventy-six subjects considered their first injury of lesser severity, 24 worse and 16 the same. Of the 24 that felt the violence of their first accident was worse, only 8 had worse symptoms, and 16 felt their symptoms were mainly the same or less than their symptoms from their second injury. Statistical analysis of the data revealed that the proportion of those claiming a difference who said the previous injury was lesser was 76% (95% CI 66–84%). The observed proportion with a lesser injury was considerably higher than the 50% anticipated. CONCLUSIONS We feel that subjects may underestimate the severity of an earlier injury and associated symptoms. Reasons for this may include secondary gain rather than any proposed cumulative effect. PMID:18201501

EXPORT CONTROLS: Change in Export Licensing Jurisdiction for Two Sensitive Dual-Use Items

National Research Council Canada - National Science Library

Spencer, F

1997-01-01

This report examines the jurisdiction shift of two items, previously controlled by the State Department to the Department of Commerce, and the implications of this change to export licensing jurisdiction...

Challenges in Evaluating Relationships Between Quantitative Data (Carbon Dioxide) and Qualitative Data (Self-Reported Visual Changes)

Science.gov (United States)

Mendez, C. M.; Foy, M.; Mason, S.; Wear, M. L.; Meyers, V.; Law, J.; Alexander, D.; Van Baalen, M.

2014-01-01

Understanding the nuances in clinical data is critical in developing a successful data analysis plan. Carbon dioxide (CO2) data are collected on board the International Space Station (ISS) in a continuous stream. Clinical data on ISS are primarily collected via conversations between individual crewmembers and NASA Flight Surgeons during weekly Private Medical Conferences (PMC). Law, et.al, 20141 demonstrated a statistically significant association between weekly average CO2 levels on ISS and self-reported headaches over the reporting period from March 14, 2001 to May 31, 2012. The purpose of this analysis is to describe the evaluation of a possible association between visual changes and CO2 levels on ISS and to discuss challenges in developing an appropriate analysis plan. METHODS & PRELIMINARY RESULTS: A first analysis was conducted following the same study design as the published work on CO2 and self-reported headaches1; substituting self-reported changes in visual acuity in place of self-reported headaches. The analysis demonstrated no statistically significant association between visual impairment characterized by vision symptoms self-reported during PMCs and ISS average CO2 levels over ISS missions. Closer review of the PMC records showed that vision outcomes are not well-documented in terms of clinical severity, timing of onset, or timing of resolution, perhaps due to the incipient nature of vision changes. Vision has been monitored in ISS crewmembers, pre- and post-flight, using standard optometry evaluations. In-flight visual assessments were limited early in the ISS program, primarily consisting of self-perceived changes reported by crewmembers. Recently, on-orbit capabilities have greatly improved. Vision data ranges from self-reported post-flight changes in visual acuity, pre- to postflight changes identified during fundoscopic examination, and in-flight progression measured by advanced on-orbit clinical imaging capabilities at predetermined testing

Reported Changes in Dietary Behavior Following a First Clinical Diagnosis of Central Nervous System Demyelination.

Science.gov (United States)

Russell, Rebecca D; Lucas, Robyn M; Brennan, Vanessa; Sherriff, Jill L; Begley, Andrea; Black, Lucinda J

2018-01-01

Although the current evidence is insufficient to recommend a special diet for people with multiple sclerosis (MS), dietary advice for people with MS is prolific online and in the media. This study aimed to describe dietary changes made in the year following a first clinical diagnosis of central nervous system demyelination (FCD), a common precursor to MS. We used follow-up data from the Ausimmune Study, a multicentre matched case-control study examining the environmental risk factors for a FCD. A total of 244 cases (60 male, 184 female) completed a 1-year follow-up interview, which included a question about dietary changes. We described the number and proportion (%) of participants who reported making dietary changes and the type of change made. We investigated independent predictors of making a dietary change using a multivariable logistic regression model. A total of 38% ( n  = 92) of participants at the 1-year follow-up reported making at least one dietary change over the last year. There were no statistically significant independent associations between any participant characteristic and odds of making a dietary change. Of those who made at least one dietary change, the most common changes were increasing fruit and/or vegetable intake (27%, n  = 25) and following a low-fat diet (25%, n  = 23). A considerable proportion of the study population reported making at least one dietary change in the year following a FCD, with the majority of changes being toward a healthier diet. Further research is warranted to investigate the reasons behind any dietary changes adopted by people with a FCD or with MS, and whether making a dietary change has benefits for the progression of demyelinating diseases, e.g., to a diagnosis of MS, as well as for general health and well-being.

Reported Changes in Dietary Behavior Following a First Clinical Diagnosis of Central Nervous System Demyelination

Directory of Open Access Journals (Sweden)

Rebecca D. Russell

2018-03-01

Full Text Available Background/objectivesAlthough the current evidence is insufficient to recommend a special diet for people with multiple sclerosis (MS, dietary advice for people with MS is prolific online and in the media. This study aimed to describe dietary changes made in the year following a first clinical diagnosis of central nervous system demyelination (FCD, a common precursor to MS.Subjects/methodsWe used follow-up data from the Ausimmune Study, a multicentre matched case-control study examining the environmental risk factors for a FCD. A total of 244 cases (60 male, 184 female completed a 1-year follow-up interview, which included a question about dietary changes. We described the number and proportion (% of participants who reported making dietary changes and the type of change made. We investigated independent predictors of making a dietary change using a multivariable logistic regression model.ResultsA total of 38% (n = 92 of participants at the 1-year follow-up reported making at least one dietary change over the last year. There were no statistically significant independent associations between any participant characteristic and odds of making a dietary change. Of those who made at least one dietary change, the most common changes were increasing fruit and/or vegetable intake (27%, n = 25 and following a low-fat diet (25%, n = 23.ConclusionA considerable proportion of the study population reported making at least one dietary change in the year following a FCD, with the majority of changes being toward a healthier diet. Further research is warranted to investigate the reasons behind any dietary changes adopted by people with a FCD or with MS, and whether making a dietary change has benefits for the progression of demyelinating diseases, e.g., to a diagnosis of MS, as well as for general health and well-being.

75 FR 54215 - Agency Request for Approval of a Previously Approved Information Collection(s): Uniform...

Science.gov (United States)

2010-09-03

... about our intention to request Office of Management and Budget (OMB) approval to renew a previously... because of management and oversight responsibilities of the agency imposed by OMB Circular 2 CFR 215 (A... Department has terminated Financial Status Report (SF-269 and SF-269A) and Federal Cash Transactions Report...

[Parathyroid cancer in a patient with previous history of hypernephroma: a clinical case].

Science.gov (United States)

Martín Navarro, J; Mendoza, E; Mateos, P; Cereceda, A; Coca, S

2007-01-01

We report the clinical case of a 55 year-old male patient, with a previous history of nephrectomy by hypernephroma sixteen years ago, first presenting hypercalcemia and rising of intact parathyroid hormone (iPTH) levels. A localization study revealed an intrathyroid nodule with cystic appearance. After undergoing a hemi-thyroidectomy, the patient is diagnosed with parathyroid carcinoma. This article analyzes previously published cases presenting parathyroidal pathologies associated with hypernephroma. A broader differential diagnosis--including the screening of parathyroidal pathologies should be considered in patients with hypercalcemia and hypernephroma.

Characterization of nuclear reactor containment penetrations. Final report

Energy Technology Data Exchange (ETDEWEB)

Shackelford, M.H.; Bump, T.R.; Seidensticker, R.W.

1985-02-01

This report concludes a preliminary report prepared by ANL for Sandia, published as NUREG/CR-3855, in June 1984. The preliminary report, NUREG/CR-3855, presented the results of a survey of nuclear reactor containment penetrations, covering the number of plants surveyed at that time (22 total). Since that time, an additional 26 plants have been included in the survey. This final report serves two purposes: (1) to add the summary data sheets and penetration details for the additional plants now included in the survey; and (2) to confirm, revise, or add to analyses and discussions presented in the first report which, of course, were based solely on the earlier sample of 22 plants. This final report follows the outline and format of the preliminary survey report. In general, changes and additions to the preliminary report are implied, rather than stated as such to avoid repeated reference to that report. If no changes have been made in a section the title of the section of the previous report is simply repeated followed by ''No Changes''. Some repetition is used for continuity and clarity.

Hanford Site Waste Management Units Report

Energy Technology Data Exchange (ETDEWEB)

Shearer, Jeffrey P. [Hanford Site (HNF), Richland, WA (United States)

2012-02-29

The Hanford Site Waste Management Units Report (HSWMUR) has been created to meet the requirements of the Tri-Party Agreement (TPA) Action Plan, Section 3.5, which states: “The Hanford Site Waste Management Units Report shall be generated, in a format agreed upon by the Parties, as a calendar year report and issued annually by the DOE by the end of February of each year, and posted electronically for regulator and public access. This report shall reflect all changes made in waste management unit status during the previous year.” This February 2012 version of the HSWMUR contains a comprehensive inventory of the 3389 sites and 540 subsites in the Waste Information Data System (WIDS). The information for each site contains a description of each unit and the waste it contains, where applicable. The WIDS database provides additional information concerning the sites contained in this report and is maintained with daily changes to these sites.

Hanford Site Waste Management Units Report

Energy Technology Data Exchange (ETDEWEB)

Shearer, Jeffrey P. [Hanford Site (HNF), Richland, WA (United States)

2013-02-13

The Hanford Site Waste Management Units Report (HSWMUR) has been created to meet the requirements of the Tri-Party Agreement (TPA) Action Plan, Section 3.5, which states: “The Hanford Site Waste Management Units Report shall be generated, in a format agreed upon by the Parties, as a calendar year report and issued annually by the DOE by the end of February of each year, and posted electronically for regulator and public access. This report shall reflect all changes made in waste management unit status during the previous year.” This February 2013 version of the HSWMUR contains a comprehensive inventory of the 3427 sites and 564 subsites in the Waste Information Data System (WIDS). The information for each site contains a description of each unit and the waste it contains, where applicable. The WIDS database provides additional information concerning the sites contained in this report and is maintained with daily changes to these sites.

Hanford Site Waste Management Units Report

Energy Technology Data Exchange (ETDEWEB)

Shearer, Jeffrey P. [Hanford Site (HNF), Richland, WA (United States)

2014-02-19

The Hanford Site Waste Management Units Report (HSWMUR) has been created to meet the requirements of the Tri-Party Agreement (TPA) Action Plan, Section 3.5, which states: “The Hanford Site Waste Management Units Report shall be generated, in a format agreed upon by the Parties, as a calendar year report and issued annually by the DOE by the end of February of each year, and posted electronically for regulator and public access. This report shall reflect all changes made in waste management unit status during the previous year.” This February 2013 version of the HSWMUR contains a comprehensive inventory of the 3438 sites and 569 subsites in the Waste Information Data System (WIDS). The information for each site contains a description of each unit and the waste it contains, where applicable. The WIDS database provides additional information concerning the sites contained in this report and is maintained with daily changes to these sites.

Third annual report 1990

International Nuclear Information System (INIS)

1990-01-01

The Independent Radiation Monitoring Scheme for Clwyd began its monitoring programme in Clwyd in 1988. This is the third report on the results of the radiation monitoring carried out within Clwyd. It identifies any changes in techniques that have occurred in the last twelve months together with the latest monitoring and analytical data. Samples of air, beach materials, coastal sand and silt, seaweed, meat, fish and milk were taken from various locations within the county. No significant changes were found from the previous two years of monitoring. The levels of radioactivity were within the limits currently being detected throughout the United Kingdom. (author)

Health effects of low-level radiation in shipyard workers: report of previous work

International Nuclear Information System (INIS)

Matanoski, G.M.

1984-01-01

Progress over the course of the Nuclear Shipyard Workers Study is reported. The derivation of the study population, the gathering of health histories, the US Navy radiation protection program, and the determination of radiation exposures is described

Identification and pathway analysis of microRNAs with no previous involvement in breast cancer.

Directory of Open Access Journals (Sweden)

Sandra Romero-Cordoba

Full Text Available microRNA expression signatures can differentiate normal and breast cancer tissues and can define specific clinico-pathological phenotypes in breast tumors. In order to further evaluate the microRNA expression profile in breast cancer, we analyzed the expression of 667 microRNAs in 29 tumors and 21 adjacent normal tissues using TaqMan Low-density arrays. 130 miRNAs showed significant differential expression (adjusted P value = 0.05, Fold Change = 2 in breast tumors compared to the normal adjacent tissue. Importantly, the role of 43 of these microRNAs has not been previously reported in breast cancer, including several evolutionary conserved microRNA*, showing similar expression rates to that of their corresponding leading strand. The expression of 14 microRNAs was replicated in an independent set of 55 tumors. Bioinformatic analysis of mRNA targets of the altered miRNAs, identified oncogenes like ERBB2, YY1, several MAP kinases, and known tumor-suppressors like FOXA1 and SMAD4. Pathway analysis identified that some biological process which are important in breast carcinogenesis are affected by the altered microRNA expression, including signaling through MAP kinases and TP53 pathways, as well as biological processes like cell death and communication, focal adhesion and ERBB2-ERBB3 signaling. Our data identified the altered expression of several microRNAs whose aberrant expression might have an important impact on cancer-related cellular pathways and whose role in breast cancer has not been previously described.

Previous Experiences with Epilepsy and Effectiveness of Information to Change Public Perception of Epilepsy

NARCIS (Netherlands)

Gutteling, Jan M.; Seydel, E.R.; Wiegman, O.

1986-01-01

Differences with regard to the effectiveness of health information and attitude change are suggested between people with direct, behavioral experiences with a health topic and people with indirect, nonbehavioral experiences. The effects of three different methods of health education about epilepsy,

Climate Change 2013. The Physical Science Basis. Working Group I Contribution to the Fifth Assessment Report of the Intergovernmental Panel on Climate Change - Abstract for decision-makers

International Nuclear Information System (INIS)

Stocker, Thomas F.; Qin, Dahe; Plattner, Gian-Kasper; Tignor, Melinda M.B.; Allen, Simon K.; Boschung, Judith; Nauels, Alexander; Xia, Yu; Bex, Vincent; Midgley, Pauline M.; Alexander, Lisa V.; Allen, Simon K.; Bindoff, Nathaniel L.; Breon, Francois-Marie; Church, John A.; Cubasch, Ulrich; Emori, Seita; Forster, Piers; Friedlingstein, Pierre; Gillett, Nathan; Gregory, Jonathan M.; Hartmann, Dennis L.; Jansen, Eystein; Kirtman, Ben; Knutti, Reto; Kumar Kanikicharla, Krishna; Lemke, Peter; Marotzke, Jochem; Masson-Delmotte, Valerie; Meehl, Gerald A.; Mokhov, Igor I.; Piao, Shilong; Plattner, Gian-Kasper; Dahe, Qin; Ramaswamy, Venkatachalam; Randall, David; Rhein, Monika; Rojas, Maisa; Sabine, Christopher; Shindell, Drew; Stocker, Thomas F.; Talley, Lynne D.; Vaughan, David G.; Xie, Shang-Ping; Allen, Myles R.; Boucher, Olivier; Chambers, Don; Hesselbjerg Christensen, Jens; Ciais, Philippe; Clark, Peter U.; Collins, Matthew; Comiso, Josefino C.; Vasconcellos de Menezes, Viviane; Feely, Richard A.; Fichefet, Thierry; Fiore, Arlene M.; Flato, Gregory; Fuglestvedt, Jan; Hegerl, Gabriele; Hezel, Paul J.; Johnson, Gregory C.; Kaser, Georg; Kattsov, Vladimir; Kennedy, John; Klein Tank, Albert M.G.; Le Quere, Corinne; Myhre, Gunnar; Osborn, Timothy; Payne, Antony J.; Perlwitz, Judith; Power, Scott; Prather, Michael; Rintoul, Stephen R.; Rogelj, Joeri; Rusticucci, Matilde; Schulz, Michael; Sedlacek, Jan; Stott, Peter A.; Sutton, Rowan; Thorne, Peter W.; Wuebbles, Donald

2013-10-01

The Working Group I contribution to the Fifth Assessment Report of the Intergovernmental Panel on Climate Change (IPCC) provides a comprehensive assessment of the physical science basis of climate change. It builds upon the Working Group I contribution to the IPCC's Fourth Assessment Report in 2007 and incorporates subsequent new findings from the Special Report on Managing the Risks of Extreme Events and Disasters to Advance Climate Change Adaptation, as well as from research published in the extensive scientific and technical literature. The assessment considers new evidence of past, present and projected future climate change based on many independent scientific analyses from observations of the climate system, paleo-climate archives, theoretical studies of climate processes and simulations using climate models. During the process of scoping and approving the outline of its Fifth Assessment Report, the IPCC focussed on those aspects of the current understanding of the science of climate change that were judged to be most relevant to policy-makers. In this report, Working Group I has extended coverage of future climate change compared to earlier reports by assessing near-term projections and predictability as well as long-term projections and irreversibility in two separate chapters. Following the decisions made by the Panel during the scoping and outline approval, a set of new scenarios, the Representative Concentration Pathways, are used across all three Working Groups for projections of climate change over the 21. century. The coverage of regional information in the Working Group I report is expanded by specifically assessing climate phenomena such as monsoon systems and their relevance to future climate change in the regions. The Working Group I Report is an assessment, not a review or a text book of climate science, and is based on the published scientific and technical literature available up to 15 March 2013. Underlying all aspects of the report is a

Reverse Shoulder Arthroplasty for the Treatment of Rotator Cuff Deficiency: A Concise Follow-up, at a Minimum of 10 Years, of Previous Reports.

Science.gov (United States)

Cuff, Derek J; Pupello, Derek R; Santoni, Brandon G; Clark, Rachel E; Frankle, Mark A

2017-11-15

We previously evaluated 94 patients (96 shoulders) who underwent reverse shoulder arthroplasty using a central compressive screw with 5.0-mm peripheral locking screws for baseplate fixation and a center of rotation lateral to the glenoid as treatment for end-stage rotator cuff deficiency. The purpose of this study was to report updated results at a minimum follow-up of 10 years. Forty patients (42 shoulders) were available for clinical follow-up. In the patients available for study, implant survivorship, with the end point being revision for any reason, was 90.7%. Since our 5-year report, 2 patients underwent revision surgery; 1 patient sustained a periprosthetic fracture 7 years postoperatively and 1 patient had a dislocation because of chronic shoulder instability at 8 years postoperatively. At a minimum follow-up of 10 years, the patients continued to maintain their improved outcome scores and range of motion, which were comparable with earlier follow-up evaluations. Therapeutic Level IV. See Instructions for Authors for a complete description of levels of evidence.

Climate change adaptation impact cost assessment in France. Second phase report. September 2009

International Nuclear Information System (INIS)

2009-01-01

Firstly, this report presents the context and challenges of works dealing with climate change adaptation assessment: observations and perspectives of climate change, concepts and definitions of adaptation to climate change, adaptation within national, European and international context, objectives and organisation of the France's inter-departmental Group. It describes the chosen methodology: hypothesis, methodological tools (climate model), bibliographical tool, and heat wave counting methodology. It discusses the present results, outlines the encountered difficulties and discusses the perspectives for future work

Malignant change of chronic ulcerative colitis: report of a case

International Nuclear Information System (INIS)

Kim, Ki Tae; Lee, Han Jin; Kang, Si Won; Bahk, Yong Whee

1988-01-01

Since the original report of Crohn and Rosenberg (1928) the association between long-standing ulcerative colitis and later development of colonic malignancy has been well known. There are many risk factors for the development of malignancy such as duration, extent, severity and age of the onset of ulcerative colitis, drugs and diagnostic radiation. The dysplasia of the colonic mucosa as a precancerous change are seen not only in the area of malignant focus but also in distant locations in long-standing ulcerative colitis. We present a case of malignant change occurred in a patient with long-standing ulcerative colitis in the rectosigmoid junction. This is probably the first documentation of malignant transformation of ulcerative colitis in the Korean literature.

Changes of biomass in some perennial grass species. | M.C. ...

African Journals Online (AJOL)

Patterns of seasonal herbaceous biomass change in a burned, ungrazed savanna woodland are reported. A standard clipping technique was used and material farmed in the current season was separated from that formed in the previous season for three perennial grass species: Brachiaria nigropedata, Andropogon ...

Responding to the challenge : the Climate Change Action Fund (CCAF) 1998-2001 report

International Nuclear Information System (INIS)

2001-01-01

In 1998, the government of Canada responded to the challenges of climate change and created the Climate Change Action Fund (CCAF) to help develop a national implementation strategy on climate change and to support early action. With the first three year phase of the CCAF complete and a new phase about to begin, this report describes the progress and achievements of the first phase of the CCAF. Results are described for the following distinct components of the CCAF: (1) foundation building, (2) technology early action measures (TEAM); science, impacts and adaptation (SIA), and public education and outreach (PEO). The government allocated $150 million over three years to accomplish goals within these four groups. Accomplishing the goals involved building on existing programs and establishing partnerships on climate change with provinces, territories and stakeholders. The report listed several general achievements in each of the four groups. The second phase of the CCAF is underway with an added fifth group to bring focus to the international aspects of the climate change issue so that Canada's vulnerabilities to climate change are better defined and opportunities are identified. The foundation building block has also been renamed. The five new blocks are called: (1) building on the future, (2) technology early action measures (TEAM), (3) science, impacts and adaptation (4) impacts and adaptation, and (5) public education and outreach. 1 tab., 1 fig

Self-Reported Changes in Attractions and Social Determinants of Mental Health in Transgender Adults.

Science.gov (United States)

Katz-Wise, Sabra L; Reisner, Sari L; White Hughto, Jaclyn M; Budge, Stephanie L

2017-07-01

This study examined associations between changes in self-reported attractions and mental health in a community-based sample of self-identified transgender adults. Participants were purposively recruited in 2013 using bimodal sampling methods and completed a one-time survey. Multivariable logistic regression models estimated adjusted risk ratios and 95 % confidence intervals to examine associations between changes in attractions and mental health outcomes (lifetime self-harm, suicide attempts, depression diagnosis; past-week clinically significant depressive distress assessed via CES-D 10) among the entire sample (N = 452; 285 female-to-male spectrum, 167 male-to-female spectrum) and after gender transition among those who had socially transitioned (n = 205; 156 female-to-male spectrum, 49 male-to-female spectrum). Models were adjusted for known population social determinants (age, race/ethnicity, gender identity, socioeconomic status, sexual orientation identity), transgender-specific determinants (age of transgender realization, social transition, medical transition, visual gender nonconformity, non-binary gender identification), and survey mode (online vs. in-person sampling). Lifetime changes in attractions were significantly associated with increased probability of all mental health outcomes; individuals reporting any change in attractions were more likely than individuals not reporting changes to indicate lifetime self-harm, suicide attempts, depression diagnosis, and current depressive distress (all ps social transition were not significantly associated with mental health outcomes. Many, but not all, population and transgender-specific social determinants were significantly associated with mental health in the full sample and among those who had socially transitioned. Clinical implications of findings about changes in attractions and mental health are discussed for transgender individuals.

77 FR 46789 - Agency Request for Renewal of a Previously Approved Collection: Disclosure of Change-of-Gauge...

Science.gov (United States)

2012-08-06

... change planes at an intermediate stop. In addition to one-flight-to-one-flight change-of-gauge services... changes planes, but in addition, the single flight to or from the exchange point itself has multiple... valuable consumer benefits, they can be confusing and misleading unless consumers are given reasonable and...

IMPACT OF TILLAGE, FERTILIZATION AND PREVIOUS CROP ON CHEMICAL PROPERTIES OF LUVISOL UNDER BARLEY FARMING SYSTEM

Directory of Open Access Journals (Sweden)

VLADIMÍR ŠIMANSKÝ

2012-01-01

Full Text Available In this paper, we report on the results of our investigation into the effects of different tillage, fertilization and previous crop on the chemical properties of loamy soil under spring barley and winter barley. We observed an increase of humus quality. More marked changes were in CT (r = 0.663, P < 0.05 than in RT (0.648, P < 0.05 and N fertilization (r = 0.678, P < 0.05 and SB (r = 0.761, P < 0.01 as well. A higher amount of TOC positively affected on parameters of soil sorptive complex in CT as well as in N and in SM treatments. A higher amount of TOC positively effected the portion of Ca2+ under CT (r= 0.795, P < 0.05, but also increased exchangeable Na+ (r= 0.830, P < 0.05 and K+ (r= 0.881, P < 0.01 in RT and N treatments.

IMPACT OF TILLAGE, FERTILIZATION AND PREVIOUS CROP ON CHEMICAL PROPERTIES OF LUVISOL UNDER BARLEY FARMING SYSTEM

Directory of Open Access Journals (Sweden)

VLADIMÍR ŠIMANSKÝ

2011-01-01

Full Text Available In this paper, we report on the results of our investigation into the effects of different tillage, fertilization and previous crop on the chemical properties of loamy soil under spring barley and winter barley. We observed an increase of humus quality. More marked changes were in CT (r = 0.663, P < 0.05 than in RT (0.648, P < 0.05 and N fertilization (r = 0.678, P < 0.05 and SB (r = 0.761, P < 0.01 as well. A higher amount of TOC positively affected on parameters of soil sorptive complex in CT as well as in N and in SM treatments. A higher amount of TOC positively effected the portion of Ca2+ under CT (r= 0.795, P < 0.05, but also increased exchangeable Na+ (r= 0.830, P < 0.05 and K+ (r= 0.881, P < 0.01 in RT and N treatments.

The Affordable Care Act, Insurance Coverage, and Health Care Utilization of Previously Incarcerated Young Men: 2008-2015.

Science.gov (United States)

Winkelman, Tyler N A; Choi, HwaJung; Davis, Matthew M

2017-05-01

To estimate health insurance and health care utilization patterns among previously incarcerated men following implementation of the Affordable Care Act's (ACA's) Medicaid expansion and Marketplace plans in 2014. We performed serial cross-sectional analyses using data from the National Survey of Family Growth between 2008 and 2015. Our sample included men aged 18 to 44 years with (n = 3476) and without (n = 8702) a history of incarceration. Uninsurance declined significantly among previously incarcerated men after ACA implementation (-5.9 percentage points; 95% confidence interval [CI] = -11.5, -0.4), primarily because of an increase in private insurance (6.8 percentage points; 95% CI = 0.1, 13.3). Previously incarcerated men accounted for a large proportion of the remaining uninsured (38.6%) in 2014 to 2015. Following ACA implementation, previously incarcerated men continued to be significantly less likely to report a regular source of primary care and more likely to report emergency department use than were never-incarcerated peers. Health insurance coverage improved among previously incarcerated men following ACA implementation. However, these men account for a substantial proportion of the remaining uninsured. Previously incarcerated men continue to lack primary care and frequently utilize acute care services.

78 FR 56816 - Vidalia Onions Grown in Georgia; Change in Reporting and Assessment Requirements

Science.gov (United States)

2013-09-16

... to regulation under the order and approximately 80 onion producers in the designated production area...; FV13-955-1 FIR] Vidalia Onions Grown in Georgia; Change in Reporting and Assessment Requirements AGENCY... the reporting and assessment requirements prescribed under the marketing order for Vidalia onions...

Change Blindness in Pigeons (Columba livia: the Effects of Change Salience and Timing

Directory of Open Access Journals (Sweden)

Walter Troy Herbranson

2015-08-01

Full Text Available Change blindness is a well-established phenomenon in humans, in which plainly visible changes in the environment go unnoticed. Recently a parallel change blindness phenomenon has been demonstrated in pigeons. The reported experiment follows up on this finding by investigating whether change salience affects change blindness in pigeons the same way it affects change blindness in humans. Birds viewed alternating displays of randomly generated lines back-projected onto three response keys, with one or more line features on a single key differing between consecutive displays. Change salience was manipulated by varying the number of line features that changed on the critical response key. Results indicated that change blindness is reduced if a change is made more salient, and this matches previous human results. Furthermore, accuracy patterns indicate that pigeons’ effective search area expanded over the course of a trial to encompass a larger portion of the stimulus environment. Thus, the data indicate two important aspects of temporal cognition. First, the timing of a change has a profound influence on whether or not that change will be perceived. Second, pigeons appear to engage in a serial search for changes, in which additional time is required to search additional locations.

New population-based exome data are questioning the pathogenicity of previously cardiomyopathy-associated genetic variants

DEFF Research Database (Denmark)

Andreasen, Charlotte Hartig; Nielsen, Jonas B; Refsgaard, Lena

2013-01-01

Cardiomyopathies are a heterogeneous group of diseases with various etiologies. We focused on three genetically determined cardiomyopathies: hypertrophic (HCM), dilated (DCM), and arrhythmogenic right ventricular cardiomyopathy (ARVC). Eighty-four genes have so far been associated with these card......Cardiomyopathies are a heterogeneous group of diseases with various etiologies. We focused on three genetically determined cardiomyopathies: hypertrophic (HCM), dilated (DCM), and arrhythmogenic right ventricular cardiomyopathy (ARVC). Eighty-four genes have so far been associated...... with these cardiomyopathies, but the disease-causing effect of reported variants is often dubious. In order to identify possible false-positive variants, we investigated the prevalence of previously reported cardiomyopathy-associated variants in recently published exome data. We searched for reported missense and nonsense...... variants in the NHLBI-Go Exome Sequencing Project (ESP) containing exome data from 6500 individuals. In ESP, we identified 94 variants out of 687 (14%) variants previously associated with HCM, 58 out of 337 (17%) variants associated with DCM, and 38 variants out of 209 (18%) associated with ARVC...

Increased Symptom Reporting in Young Athletes Based on History of Previous Concussions.

Science.gov (United States)

Moser, Rosemarie Scolaro; Schatz, Philip

2017-01-01

Research documents increased symptoms in adolescents with a history of two or more concussions. This study examined baseline evaluations of 2,526 younger athletes, ages 10 to 14. Between-groups analyses examined Post Concussion Symptom Scale symptoms by concussion history group (None, One, Two+) and clusters of Physical, Cognitive, Emotional, and Sleep symptoms. Healthy younger athletes with a concussion history reported greater physical, emotional, and sleep-related symptoms than those with no history of concussion, with a greater endorsement in physical/sleep symptom clusters. Findings suggest younger athletes with a history of multiple concussions may experience residual symptoms.

Change Best.Task 2.1. National Report on the Energy Efficiency Service Business in the Netherlands

International Nuclear Information System (INIS)

Boonekamp, P.; Vethman, P.

2009-11-01

The aim of the Change Best project is to promote the development of an energy efficiency service (EES) market and to give good practice examples of changes in energy service business, strategies, and supportive policies and measures in the course of the implementation of Directive 2006/32/EC on Energy End-Use Efficiency and Energy Services. This report addresses Task 2.1: National Report on the Energy Efficiency Service Business in the Netherlands. More information can be found on the website of Change Best at www.changebest.eu.

Urinary tract infections in hospital pediatrics: many previous antibiotherapy and antibiotics resistance, including fluoroquinolones.

Science.gov (United States)

Garraffo, A; Marguet, C; Checoury, A; Boyer, S; Gardrat, A; Houivet, E; Caron, F

2014-02-01

We studied antibiotic resistance in pediatric UTIs and we evaluated the impact of antibiotic exposure in the previous 12 months, very little French data being available for this population. We conducted a multicenter prospective study including children consulting for, or admitted in 2 hospitals. Prior antibiotic exposure was documented from their health record. One hundred and ten patients (73 girls), 11 days to 12 years of age, were included in 10 months. Ninety-six percent presented with pyelonephritis, associated to uropathy for 25%. Escherichia coli was predominant (78%), followed by Proteus spp. and Enterococcus spp. The antibiotic resistance rate of E. coli was high and close to that reported for adults with complicated UTIs: amoxicillin 60%, amoxicillin-clavulanate 35%, cefotaxim 5%, trimethoprim-sulfametoxazole 26%, nalidixic acid 9%, ciprofloxacin 7%, gentamycin 1%, nitrofurantoin and fosfomycin 0%. The antibiotic exposure in the previous 12 months involved 62 children (56%) most frequently with β-lactams (89%) for a respiratory tract infection (56%). A clear relationship between exposure and resistance was observed for amoxicillin (71% vs. 46%), first generation (65% vs. 46%) and third generation (9% vs. 3%) cephalosporins, or trimethoprim-sulfamethoxazole (36% vs. 15%). However, antibiotic exposure could not account alone for the results, as suggested by the 7% of ciprofloxacin resistance, observed without any identified previous treatment. Bacterial species and antibiotic resistance level in children are similar to those reported for adults. Antibiotic exposure in the previous 12 months increases the risk of resistance but other factors are involved (previous antibiotic therapies and fecal-oral or mother-to-child transmission). Copyright © 2013 Elsevier Masson SAS. All rights reserved.

Prospective monitoring and self-report of previous falls among older women at high risk of falls and fractures: a study of comparison and agreement.

Science.gov (United States)

Garcia, Patrícia A; Dias, João M D; Silva, Silvia L A; Dias, Rosângela C

2015-01-01

The identification of the occurrence of falls is an important step for screening and for rehabilitation processes for the elderly. The methods of monitoring these events are susceptible to recording biases, and the choice of the most accurate method remains challenging. (i) To investigate the agreement between retrospective self-reporting and prospective monitoring of methods of recording falls, and (ii) to compare the retrospective self-reporting of falls and the prospective monitoring of falls and recurrent falls over a 12-month period among older women at high risk of falls and fractures. A total of 118 community-dwelling older women with low bone density were recruited. The incidence of falls was monitored prospectively in 116 older women (2 losses) via monthly phone calls over the course of a year. At the end of this monitoring period, the older women were asked about their recall of falls in the same 12-month period. The agreement between the two methods was analyzed, and the sensitivity and specificity of self-reported previous falls in relation to the prospective monitoring were calculated. There was moderate agreement between the prospective monitoring and the retrospective self-reporting of falls in classifying fallers (Kappa = 0.595) and recurrent fallers (Kappa = 0.589). The limits of agreement were 0.35 ± 1.66 falls. The self-reporting of prior falls had a 67.2% sensitivity and a 94.2% specificity in classifying fallers among older women and a 50% sensitivity and a 98.9% specificity in classifying recurrent fallers. Self-reporting of falls over a 12-month period underestimated 32.8% of falls and 50% of recurrent falls. The findings recommend caution if one is considering replacing monthly monitoring with annual retrospective questioning.

17 CFR 3.31 - Deficiencies, inaccuracies, and changes, to be reported.

Science.gov (United States)

2010-04-01

..., that where a registrant is reporting a change in the form of organization from or to a sole... registrant as a floor broker, floor trader or associated person, each person who qualifies for the temporary... floor trader, or whose name appears on a list of floor traders submitted in accordance with § 1.66(a) of...

Plasma volume changes during hypoglycaemia: the effect of arterial blood sampling

DEFF Research Database (Denmark)

Hilsted, J; Bendtsen, F; Christensen, N J

1990-01-01

To investigate whether previously reported changes in venous blood volume and composition induced by acute hypoglycaemia in humans are representative for the entire body we measured erythrocyte 51Cr content, haematocrit, plasma volume, intravascular albumin content and transcapillary escape rate...... hypoglycaemia. The magnitude of the changes in arterial and venous blood were not significantly different. These results indicate that the above changes in blood volume and composition are whole-body phenomena: furthermore, the major part of the changes are likely to occur in tissues other than upper extremity...

Blood pressure and fasting lipid changes after 24 weeks' treatment with vildagliptin: a pooled analysis in >2,000 previously drug-naïve patients with type 2 diabetes mellitus.

Science.gov (United States)

Evans, Marc; Schweizer, Anja; Foley, James E

2016-01-01

We have previously shown modest weight loss with vildagliptin treatment. Since body weight balance is associated with changes in blood pressure (BP) and fasting lipids, we have assessed these parameters following vildagliptin treatment. Data were pooled from all double-blind, randomized, controlled, vildagliptin mono-therapy trials on previously drug-naïve patients with type 2 diabetes mellitus who received vildagliptin 50 mg once daily (qd) or twice daily (bid; n=2,108) and wherein BP and fasting lipid data were obtained. Data from patients receiving vildagliptin 50 mg qd or bid showed reductions from baseline to week 24 in systolic BP (from 132.5±0.32 to 129.8±0.34 mmHg; Pvildagliptin shows a significant reduction in BP and a favorable fasting lipid profile that are associated with modest weight loss.

Streptococcus agalactiae endocarditis presenting as acalculous cholecystitis in a previously well woman.

LENUS (Irish Health Repository)

Brewer, Linda

2013-01-01

This case report describes the unusual presentation of a previously very well woman with Streptococcus agalactiae endocarditis in the emergency department. History, examination and preliminary laboratory and radiological investigations supported a diagnosis of acalculous cholecystitis, for which she was given intravenous broad spectrum antimicrobial therapy. One day following admission, the patient deteriorated and became unresponsive. Subsequent MRI of the brain revealed multiple bihemispheric cerebral emboli and a large, mobile mitral valve thrombus was visualised on her transoesophageal echocardiogram. S agalactiae was cultured from venous blood samples and her antimicrobial cover was adjusted accordingly. Despite her presumed guarded prognosis, this patient made a remarkable recovery. To our knowledge, the association of S agalactiae endocarditis with acalculous cholecystitis has not been previously described.

Pregnancy in a Previously Conjoined Thoracopagus Twin with a Crisscross Heart

Directory of Open Access Journals (Sweden)

Bassam H. Rimawi

2015-01-01

Full Text Available Background. Crisscross heart (CCH is a complex, rare, congenital, rotational, cardiac abnormality that accounts for <0.1% of congenital heart defects (CHD. CCH is characterized by the crossing of the inflow streams of the two ventricles due to an abnormal twisting of the heart. A case of maternal CCH has not been previously reported. Case. We report a case of a primigravida with a CCH, who was separated at birth from her thoracopagus conjoined twin. Pregnancy was managed by congenital cardiology, maternal-fetal medicine, anesthesiology, and obstetrics. She underwent a 39-week vaginal delivery without maternal or neonatal complication. Conclusion. A successful term pregnancy outcome was achieved in a patient with CCH using a multidisciplinary approach to address her cardiac condition.

Effects of previous growth hormone excess and current medical treatment for acromegaly on cognition

NARCIS (Netherlands)

Brummelman, Pauline; Koerts, Janneke; Dullaart, Robin P. F.; van den Berg, Gerrit; Tucha, Oliver; Wolffenbuttel, Bruce H. R.; van Beek, Andre P.

2012-01-01

Background In untreated acromegaly patients, decreased cognitive functioning is reported to be associated with the degree of growth hormone (GH) and IGF-1 excess. Whether previous GH excess or current medical treatment for acromegaly specifically affects cognition remains unclear. The aim of this

Revision and simplification of the boarding previous minimum of the lumbar column

International Nuclear Information System (INIS)

Lazannec, JY; Del Vecchio, R; Ramare, S; Saillant, G

2001-01-01

This paper describes the boarding retroperineal previous minimum, which provides access at any level discal and vertebral between T12 and S1. It is carried out a technique of dissection retroperineal that facilitates the renal and duodenum-pancreatic mobilization to consent to the face previous left of the whole lumbar column and of the thoracic-lumbar union. They were carried out careful anatomical dissections in fresh cadavers and preserved to determine the topography and the anatomical relationships of interest and this way to develop a sure boarding and easily reproducible. Special attention has been paid to the description of the lumbar veins and the anastomosis between the vein renal left and the hemiacigos system for the exhibition of the expensive left anterolateral of T12 and L1. A series of 94 patients is reported with lesions caused by traumas or degenerative processes. For all the lumbar levels, even in-patient with antecedents of surgery intraperitoneal, the boarding minimum retroperitoneal, was safe for the kidneys, ureters, spleen, hypo gastric plexus and duodenum-pancreatic union. Better cosmetic results are reported, decrease of the time surgical, scarce bled intraoperatory and easiness for the decortications and placement of implants. The previous boarding minimum retro peritoneal of the column developed starting from the boarding classic retroperineals, offers significant advantages on the endoscopic techniques, which require sophisticated machinery and they are technically plaintiffs. The exhibition of all the lumbar levels, as well as the reduction maneuvers and placement of implants, they can be carried out with easiness without causing muscular damage

Long-term effects of previous oxandrolone treatment in adult women with Turner syndrome

NARCIS (Netherlands)

K. Freriks (Kim); T.C.J. Sas (Theo); T. Traas (Theo); R.T. Netea-Maier (Romana ); M. den Heijer (Martin); A.R.M.M. Hermus (Ad); J.M. Wit (Jan); J.A.E.M. Van Alfen-van Der Velden (Janiëlle A. E.); B.J. Otten (Barto); S.M.P.F. de Muinck Keizer-Schrama (Sabine); M. Gotthardt (Martin); P.H. Dejonckere (Philippe); G.R.J. Zandwijken (Gladys); L.A. Menke (Leonie); H.J.L.M. Timmers

2013-01-01

textabstractObjective: Short stature is a prominent feature of Turner syndrome (TS), which is partially overcome by GH treatment. We have previously reported the results of a trial on the effect of oxandrolone (Ox) in girls with TS. Ox in a dose of 0.03 mg/kg per day (Ox 0.03) significantly

Functional MRI of the visual cortex and visual testing in patients with previous optic neuritis

DEFF Research Database (Denmark)

Langkilde, Annika Reynberg; Frederiksen, J.L.; Rostrup, Egill

2002-01-01

of the activated area and the signal change following ON, and compared the results with results of neuroophthalmological testing. We studied nine patients with previous acute ON and 10 healthy persons served as controls using fMRI with visual stimulation. In addition to a reduced activated volume, patients showed...... a reduced blood oxygenation level dependent (BOLD) signal increase and a greater asymmetry in the visual cortex, compared with controls. The volume of visual cortical activation was significantly correlated to the result of the contrast sensitivity test. The BOLD signal increase correlated significantly......The volume of cortical activation as detected by functional magnetic resonance imaging (fMRI) in the visual cortex has previously been shown to be reduced following optic neuritis (ON). In order to understand the cause of this change, we studied the cortical activation, both the size...

National Institute for Global Environmental Change. Semi-annual report, July 1, 1991--December 31, 1991

Energy Technology Data Exchange (ETDEWEB)

Werth, G.C.

1992-04-01

This document is the Semi-Annual Report of the National Institute for Global Environmental Change for the reporting period July 1 to December 31, 1991. The report is in two parts. Part I presents the mission of the Institute, examples of progress toward that mission, a brief description of the revised management plan, and the financial report. Part II presents the statements of the Regional Center Directors along with progress reports of the projects written by the researchers themselves.

Study of some physical aspects previous to design of an exponential experiment

International Nuclear Information System (INIS)

Caro, R.; Francisco, J. L. de

1961-01-01

This report presents the theoretical study of some physical aspects previous to the design of an exponential facility. The are: Fast and slow flux distribution in the multiplicative medium and in the thermal column, slowing down in the thermal column, geometrical distribution and minimum needed intensity of sources access channels and perturbations produced by possible variations in its position and intensity. (Author) 4 refs

Land-Use Scenarios: National-Scale Housing-Density Scenarios Consistent with Climate Change Storylines (Final Report)

Science.gov (United States)

EPA announced the availability of the final report, Land-Use Scenarios: National-Scale Housing-Density Scenarios Consistent with Climate Change Storylines. This report describes the scenarios and models used to generate national-scale housing density scenarios for the con...

Modular femoral component for conversion of previous hip surgery in total hip arthroplasty.

Science.gov (United States)

Goldstein, Wayne M; Branson, Jill J

2005-09-01

The conversion of previous hip surgery to total hip arthroplasty creates a durable construct that is anatomically accurate. Most femoral components with either cemented or cementless design have a fixed tapered proximal shape. The proximal femoral anatomy is changed due to previous hip surgery for fixation of an intertrochanteric hip fracture, proximal femoral osteotomy, or a fibular allograft for avascular necrosis. The modular S-ROM (DePuy Orthopaedics Inc., Warsaw, Ind) hip stem accommodates these issues and independently prepares the proximal and distal portion of the femur. In preparation and implantation, the S-ROM hip stem creates less hoop stresses on potentially fragile stress risers from screws and thin bone. The S-ROM hip stem also prepares a previously distorted anatomy by milling through cortical bone that can occlude the femoral medullar canals and recreate proper femoral anteversion and reduces the risk of intraoperative or postoperative periprosthetic fracture due to the flexible titanium-slotted stem. The S-ROM femoral stem is recommended for challenging total hip reconstructions.

76 FR 37376 - Sunshine Act Meeting Federal Register Citation of Previous Announcement: 76 FR 35472, June 17, 2011

Science.gov (United States)

2011-06-27

... DEPARTMENT OF JUSTICE Parole Commission Sunshine Act Meeting Federal Register Citation of Previous Announcement: 76 FR 35472, June 17, 2011 PREVIOUSLY ANNOUNCED TIME AND DATE OF THE MEETING: 10 a.m., Tuesday, June 21, 2011. CHANGES IN THE MEETING: Removal of agenda item 5: Discussion and vote on a final rule on...

Climate change, impacts and vulnerability in Europe 2012. An indicator-based report

Energy Technology Data Exchange (ETDEWEB)

NONE

2012-11-15

This European Environment Agency (EEA) report presents information on past and projected climate change and related impacts in Europe, based on a range of indicators. The report also assesses the vulnerability of society, human health and ecosystems in Europe and identifies those regions in Europe most at risk from climate change. Furthermore, the report discusses the principle sources of uncertainty for the indicators and notes how monitoring and scenario development can improve our understanding of climate change, its impacts and related vulnerabilities. Some key findings: The last decade (2002-2011) was the warmest on record in Europe, with European land temperature 1.3 deg. C warmer than the pre-industrial average. Various model projections show that Europe could be 2.5-4 deg. C warmer in the later part of the 21st Century, compared to the 1961-1990 average. Heat waves have increased in frequency and length, causing tens of thousands of deaths over the last decade. The projected increase in heat waves could increase the number of related deaths over the next decades, unless societies adapt, the report says. However, cold-related deaths are projected to decrease in many countries. While precipitation is decreasing in southern regions, it is increasing in northern Europe, the report says. These trends are projected to continue. Climate change is projected to increase river flooding, particularly in northern Europe, as higher temperatures intensify the water cycle. However, it is difficult to discern the influence of climate change in flooding data records for the past. River flow droughts appear to have become more severe and frequent in southern Europe. Minimum river flows are projected to decrease significantly in summer in southern Europe but also in many other parts of Europe to varying degrees. The Arctic is warming faster than other regions. Record low sea ice was observed in the Arctic in 2007, 2011 and 2012, falling to roughly half the minimum extent seen

POEMS syndrome (polyneuropathy, organomegaly, endocrinopathy, multiple myeloma and skin changes) with cranial vault plasmocytoma and the role of surgery in its management: a case report.

Science.gov (United States)

Plata Bello, Julio; Garcia-Marin, Victor

2013-10-18

POEMS syndrome (an acronym of polyneuropathy, organomegaly, endocrinopathy, multiple myeloma and skin changes) is a paraneoplastic disorder related to an underlying plasma cell dyscrasia. The development of such a syndrome is rare and its association with calvarial plasmocytoma is even less common, with only two previous reported cases. We describe, in detail, an unusual presentation of cranial plasmocytoma associated with POEMS syndrome and briefly discuss the possible role of surgery in the management of this disease. We present the case of a 45-year-old Caucasian man who was admitted to our department presenting with progressive weakness in his lower limbs, enlarged lymph nodes and a large mass on the scalp with intense bone erosion. POEMS criteria were present and pathological studies confirmed a Castleman's variant plasmocytoma. Clinical status improved noticeably after the excision of the plasmocytoma and the treatment was completed with radiotherapy and steroid pulse therapy. Cranial vault plasmocytoma and its association with POEMS syndrome are rare conditions with few previously reported cases. Although the role of surgery is not clearly defined in POEMS syndrome guidelines, the fact that there seems to be a better prognosis and clinical outcome when surgery is used as a part of the management in POEMS syndrome with cranial vault plasmocytoma is worth discussing.

Long-term effects of previous oxandrolone treatment in adult women with Turner syndrome

NARCIS (Netherlands)

Freriks, K.; Sas, T.C.J.; Traas, M.A.F.; Netea-Maier, R.T.; Heijer, M. den; Hermus, A.R.M.M.; Wit, J.M.; Alfen-van der Velden, J. van; Otten, B.J.; Muinck Keizer-Schrama, S.M.P.F. de; Gotthardt, M.; Dejonckere, P.H.; Zandwijken, G.R.; Menke, L.A.; Timmers, H.J.L.M.

2013-01-01

OBJECTIVE: Short stature is a prominent feature of Turner syndrome (TS), which is partially overcome by GH treatment. We have previously reported the results of a trial on the effect of oxandrolone (Ox) in girls with TS. Ox in a dose of 0.03 mg/kg per day (Ox 0.03) significantly increased adult

OCRWM procedure for reporting software baseline change information

International Nuclear Information System (INIS)

1994-07-01

The purpose of this procedure is to establish a requirement and method for participant organizations to report software baseline change information to the M ampersand O Configuration Management (CM) organization for inclusion in the OCRWM Configuration Information System (CIS). (The requirements for performing software configuration management (SCM) are found in the OCRWM Quality Assurance Requirements and Description (QARD) document and in applicable DOE orders, and not in this procedure.) This procedure provides a linkage between each participant's SCM system and the CIS, which may be accessed for identification, descriptive, and contact information pertaining to software released by a participant. Such information from the CIS will enable retrieval of details and copies of software code and documentation from the participant SCM system

Social identity change in response to discrimination.

Science.gov (United States)

Perozzo, Cristina; de la Sablonnière, Roxane; Auger, Emilie; Caron-Diotte, Mathieu

2016-09-01

This study investigated the conditions under which discrimination can lead to social identity changes among members of a minority group. Both positive and negative relations between perceptions of discrimination and social identity have previously been reported. To explain the conflicting results and understand the complex reality of members of stigmatized groups, we argue that group-based emotions (e.g., group-based dissatisfaction) and ambiguity of discrimination cues (i.e., overt vs. ambiguous) need to be considered. We hypothesized that perceptions of discrimination would play a moderating role between group-based dissatisfaction and social identity change in a context of ambiguous, but not of overt, discrimination. The sample was comprised of 151 Arab Muslims living in the province of Quebec. Participants read fictitious newspaper articles portraying either overt (n = 76) or ambiguous (n = 75) discrimination towards in-group members. Results revealed that for participants in the overt discrimination condition, only group-based dissatisfaction was positively associated with social identity change. In contrast, for the participants in the ambiguous discrimination condition, those who perceived little discrimination and felt low group-based dissatisfaction reported a decrease in social identity. However, those who perceived low group discrimination and felt high group-based dissatisfaction reported a positive social identity change. © 2016 The British Psychological Society.

Clear cell hidradenocarcinoma--a case report with unusual in situ malignant changes.

Science.gov (United States)

Al-Irhayim, B

1984-05-01

Clear cell hidradenocarcinoma is a rare tumour, the histogenesis of which has been much debated in the past. However, it is now considered a tumour of sweat gland origin. Presented herewith is a report of a case with unusual histological features of in situ malignant changes within sweat glands. These changes very closely simulate lobular cancerisation of the breast. On reviewing the English literature on the histopathology of sweat gland tumours, we have not found similar histological findings. These histological findings provide supportive evidence of the sweat gland origin of these tumours.

Retreatment with sofosbuvir/velpatasvir in cirrhotic patients with genotype-4 who failed a previous interferon-free regimen: a case series.

Science.gov (United States)

Boglione, Lucio; Pinna, Simone Mornese; Lupia, Tommaso; Cariti, Giuseppe; Di Perri, Giovanni

2018-02-14

The novel available interferon (IFN)-free regimens significantly improved the sustained virological response (SVR) in patients with chronic hepatitis C (CHC), without important side effects and with shorter duration of treatment. In a subset of patients, however, the treatment failure (TF) was due to the presence of resistance-associated substitutions (RAS) that lead to virological breakthrough (BT) or relapse. We analysed in this case series the role of RAS on the TF in cirrhotic patients with genotype (GT)4, treated with a previous IFN-free regimen, and retreated with the combination of sofosbuvir (SOF)/velpatasvir (VEL) for 12 or 24 weeks, without ribavirin (RBV). We included in this analysis all patients with GT4 who failed a previous IFN-free treatment, with the presence of RAS at BT or relapse. All patients were retreated with a fixed combination of SOF/VEL for 12/24 weeks, without RBV. We evaluated the SVR and the MELD score change after the treatment. Seven patients were described. All were cirrhotic, Child-Pugh A (n=5), B (n=2); baseline RAS were detected in 4/7 subjects; at post-treatment detection, NS5 RAS were: F28S (n=1), Q30K (n=2), S30G (n=1), NS3 were: S122R (n=1), S122G (n=2), D168V (n=3). All retreated patients gained SVR. MELD score improved in all subjects with a median change of 3 points. No significant side effects or adverse events were reported. The combination SOF/VEL could be considered for the retreatment of cirrhotic GT4 patients who failed a previous IFN-free treatment with the presence of RAS in NS3 or NS5 regions.

Retreatment with sofosbuvir/velpatasvir in cirrhotic patients with genotype 4 who failed a previous interferon-free regimen: a case series.

Science.gov (United States)

Boglione, Lucio; Pinna, Simone Mornese; Lupia, Tommaso; Cariti, Giuseppe; Di Perri, Giovanni

2018-02-14

The novel available interferon (IFN)-free regimens significantly improved the sustained virological response (SVR) in patients with chronic hepatitis C (CHC), without important side-effects and with shorter duration of treatment. In a subset of patients, however, the treatment failure (TF) was due to the presence of resistance-associated substitutions (RAS) that lead to virological breakthrough (BT) or relapse. We analyzed in this case-series the role of RAS on the TF in cirrhotic patients with GT4, treated with a previous IFN-free regimen, and retreated with the combination of sofosbuvir (SOF)/velpatasvir (VEL) for 12 or 24 weeks, without ribavirin (RBV). We included in this analysis all patients with GT4 who failed a previous IFN-free treatment, with the presence of RAS at BT or relapse. All patients were retreated with a fixed combination of SOF/VEL for 12/24 weeks, without RBV. We evaluated the SVR and the MELD score change after the treatment. Seven patients were described. All were cirrhotic, Child-Pug A (n=5), B (n=2); baseline RAS were detected in 4/7 subjects; at post-treatment detection, NS5 RAS were: F28S (n=1), Q30K (n=2), S30G (n=1), NS3 were: S122R (n=1), S122G (n=2), D168V (n=3). All retreated patients gained the SVR. MELD score improved in all subjects with a median change of 3 points. No significant side-effects or adverse events were reported. The combination SOF/VEL could be considered for the retreatment of cirrhotic GT4 patients who failed a previous IFN-free treatment with the presence of RAS in NS3 or NS5 regions.

Ecosystem services and livelihoods - Vulnerability and adaption to a changing climate. VACCIA Synthesis Report

Energy Technology Data Exchange (ETDEWEB)

Bergstroem, I.; Mattson, T.; Niemelae, E.; Vuorenmaa, J.; Forsius, M. (eds.)

2011-12-15

This report is a summary of results from the project Vulnerability Assessment of Ecosystem Services for Climate Change Impacts and Adaptation (VACCIA), funded by the European Union's LIFE+ programme. Partners in the extensive three-year (2009-2011) project, coordinated by the Finnish Environment Institute (SYKE), included the Finnish Meteorological Institute, the University of Helsinki, the University of Jyvaeskylae and the University of Oulu. Key results from the 13 VACCIA Actions are compiled in the summary. The Actions assessed the threats and challenges posed by climate change to ecosystem services and livelihoods, and suggested methods for adapting to changing conditions. The report also highlights further research needs. The publication's introduction describes the ecosystem service concept and provides an insight into policy processes for handling ecosystem services and their adaptation to a changing climate. Results of the Actions are assembled in the following three chapters, the first presenting key methods used in the project for monitoring changes and predicting future changes, the second describing the change in ecosystem services, and the third reviewing vulnerability and adaptation. An extensive summary section is also included. Annexed tables present the project's key results and conclusions compactly, alongside the resulting adaptation challenges and needs for further research. Monitoring and prediction of changes is based, e.g. on climate and air quality scenarios produced by the project, and remote sensing and geographic information materials. Of ecosystem services, those produced by catchments and water bodies are examined, alongside changes in the biodiversity of coastal, water and forest environments, studied with the help of sample species. Ecosystem services needed by urban areas are examined from the viewpoint of climate change and changes in land use. Among livelihoods, agriculture, forestry, fisheries and tourism are

Massachusetts shoreline change project: a GIS compilation of vector shorelines and associated shoreline change data for the 2013 update

Science.gov (United States)

Smith, Theresa L.; Himmelstoss, Emily A.; Thieler, E. Robert

2013-01-01

Identifying the rates and trends associated with the position of the shoreline through time presents vital information on potential impacts these changes may have on coastal populations and infrastructure, and supports informed coastal management decisions. This report publishes the historical shoreline data used to assess the scale and timing of erosion and accretion along the Massachusetts coast from New Hampshire to Rhode Island including all of Cape Cod, Martha’s Vineyard, Nantucket and the Elizabeth Islands. This data is an update to the Massachusetts Office of Coastal Zone Management Shoreline Change Project. Shoreline positions from the past 164 years (1845 to 2009) were used to compute the shoreline change rates. These data include a combined length of 1,804 kilometers of new shoreline data derived from color orthophoto imagery collected in 2008 and 2009, and topographic lidar collected in 2007. These new shorelines have been added to previously published historic shoreline data from the Massachusetts Office of Coastal Zone Management and the U.S. Geological Survey. A detailed report containing a discussion of the shoreline change data presented here and a summary of the resulting rates is available and cited at the end of the Introduction section of this report.

A new model for the mental health nursing change of shift report.

Science.gov (United States)

Priest, C S; Holmberg, S K

2000-08-01

Nursing shift reports are intended to enhance the continuity and quality of nursing care delivered by providing results of nursing assessments, summarizing medical information, and drawing attention to specific nursing interventions and goals anticipated during the upcoming shift. In this article, contemporary literature on shift reports is reviewed with specific attention to the unique characteristics and problems that commonly occur in change of shift reports in a mental health setting. The framework proposed is Gordon's functional health patterns because it provides a holistic structure for organizing patient data in a clear, objective manner. Additional methods for enhancing shift reports are recommended, including the use of specific behavioral descriptions, the inclusion of data from targeted nursing assessments, and the discussion of alternative care approaches that support the development of consistent, collaborative nursing interventions across shifts. A case example is used for demonstration.

Pushing the boundaries in liver graft utilisation in transplantation: Case report of a donor with previous bile duct injury repair.

Science.gov (United States)

Sultana, Asma; Powell, James J; Oniscu, Gabriel C

2017-01-01

Liver transplantation is a recognised treatment for extensive bile duct injuries with secondary biliary cirrhosis or recurring sepsis. However, there have been no reports of successful liver transplantation from a donor who sustained a previous bile duct injury. Here we discuss the case of a liver transplant from a 51-year-old brain dead donor who had suffered a Strasberg E1 bile duct injury and had undergone a Roux-en-Y hepaticojejunostomy 24 years prior to donation. The liver was successfully recovered and transplanted into a 56-year-old male recipient with end stage liver disease consequent to alpha 1 antitrypsin deficiency. The graft continues to function well 36 months post-transplant, with normal liver function tests and imaging revealing a patent hepaticojejunostomy. The potential associated vascular injuries should be identified during bench preparation whilst the management of biliary reconstruction at the time of transplant should follow the principles of biliary reconstruction in cases with biliary injuries, extending the hilar opening into the left duct. This case highlights the successful utilisation of a post bile duct injury repair liver, employing an experienced procurement team and careful bench assessment and reconstruction. Copyright © 2017. Published by Elsevier Ltd.

Previous bacterial infection affects textural quality parameters of heat-treated fillets from rainbow trout (Oncorhynchus mykiss)

DEFF Research Database (Denmark)

Ingerslev, Hans-Christian; Hyldig, Grethe; Przybylska, Dominika Alicja

2012-01-01

Sensory quality of fish meat is influenced by many parameters prior to slaughter. In the present study, it was examined if previous infections or damages in the muscle tissue influence product quality parameters in fish. Fillets from rainbow trout (Oncorhynchus mykiss) reared in seawater....... This article was the first to describe a correlation between previous infections in fish and changes in sensory-quality parameters. PRACTICAL APPLICATIONS. This work contributes with knowledge about sensory-quality parameters of fish meat after recovery from infections and physical-tissue damage. Because...... the results demonstrate an influence on the texture from previous disease, the practical potentials of the results are valuable for the aquaculture industry. In order to minimize the effects of previous diseases on the sensory quality regarding the texture, these fishes should be processed as cold...

[Lessons from abroad. Current and previous crisis in other countries. SESPAS report 2014].

Science.gov (United States)

Rivadeneyra-Sicilia, Ana; Minué Lorenzo, Sergio; Artundo Purroy, Carlos; Márquez Calderón, Soledad

2014-06-01

The evidence available on the impact of previous crises on health reveals different patterns attributable to study designs, the characteristics of each crisis, and other factors related to the socioeconomic and political context. There is greater consensus on the mediating role of government policy responses to financial crises. These responses may magnify or mitigate the adverse effects of crises on population health. Some studies have shown a significant deterioration in some health indicators in the context of the current crisis, mainly in relation to mental health and communicable diseases. Alcohol and tobacco use have also declined in some European countries. In addition, this crisis is being used by some governments to push reforms aimed at privatizing health services, thereby restricting the right to health and healthcare. Specifically, action is being taken on the three axes that determine health system financing: the population covered, the scope of services, and the share of the costs covered. These measures are often arbitrarily implemented based on ideological decisions rather than on the available evidence and therefore adverse consequences are to be expected in terms of financial protection, efficiency, and equity. Copyright © 2013 SESPAS. Published by Elsevier Espana. All rights reserved.

Are the Projections of Future Climate Change Reliable in the IPCC Reports?

Institute of Scientific and Technical Information of China (English)

Zongci Zhao

2011-01-01

@@ As we know,the projections of future climate change including impacts and strategies in the IPCC Assessment Reports were based on global climate models with scenarios on various human activities.Global climate model simulations provide key inputs for climate change assessments. In this study,the main objective is to analyze if the projections of fu-ture climate change by global climate models are reli-able.Several workshops have been held on this issue,such as the IPCC expert meeting on assessing and combining multi-model climate projections in January of 2010 (presided by the co-chairs of the IPCC WGI and WGII AR5),and the workshop of the combined global climate model group held by NCAR in June of 2010.

Plasma volume changes during hypoglycaemia

DEFF Research Database (Denmark)

Hilsted, J; Bendtsen, F; Christensen, N J

1990-01-01

To investigate whether previously reported changes in venous blood volume and composition induced by acute hypoglycaemia in humans are representative for the entire body we measured erythrocyte 51Cr content, haematocrit, plasma volume, intravascular albumin content and transcapillary escape rate...... of albumin in arterial and venous blood in seven healthy subjects before and during insulin-induced hypoglycaemia. In both vascular sites blood 51Cr content and the haematocrit increased, plasma volume and intravascular albumin content decreased and the transcapillary escape rate of albumin increased during...

Functional MRI of the visual cortex and visual testing in patients with previous optic neuritis

DEFF Research Database (Denmark)

Langkilde, Annika Reynberg; Frederiksen, J.L.; Rostrup, Egill

2002-01-01

to both the results of the contrast sensitivity test and to the Snellen visual acuity. Our results indicate that fMRI is a useful method for the study of ON, even in cases where the visual acuity is severely impaired. The reduction in activated volume could be explained as a reduced neuronal input......The volume of cortical activation as detected by functional magnetic resonance imaging (fMRI) in the visual cortex has previously been shown to be reduced following optic neuritis (ON). In order to understand the cause of this change, we studied the cortical activation, both the size...... of the activated area and the signal change following ON, and compared the results with results of neuroophthalmological testing. We studied nine patients with previous acute ON and 10 healthy persons served as controls using fMRI with visual stimulation. In addition to a reduced activated volume, patients showed...

Giant fibroadenomatoid hyperplasia of the breast: a case report.

Science.gov (United States)

Zhang, Hao; Wang, Xin-Lu; Ren, Wei-Dong; Shi, Tie-Mei

2014-01-01

Fibroadenomatoid hyperplasia of the breast (FAHB) is a rare benign breast lesion and its clinical features are similar to fibroadenoma and fibrocystic changes. FAHB has been previously termed sclerosing lobular hyperplasia, fibroadenomatosis, fibroadenomatoid change, or fibroadenomatoid mastopathy. Typically, FAHB is derived from stroma and epithelia. The pathologic characteristics of FAHB are microfocal lobulocentric proliferation of stroma accompanied by epithelial and myoepithelial components resembling similar histological changes, as found in fibroadenoma, apocrine hyperplasia, intraductal hyperplasia, and lobular hyperplasia. FAHB could be present as a localized or diffused pattern in pathology. Most cases show no well-circumscribed mass lesions and no apparent capsules; it is usually identified as an incidental finding in other benign lesions or in random sampling in cancerous breast tissues. FAHB is categorized as a benign proliferative breast disease and it has previously been reported; however, the authors believe this study may be the first case with two giant masses reported. Fiber adenoma hyperplasia is a rare cystic hyperplasia of breast pathology and its ultrasonographic manifestations are easily confused with breast cancer. Comparative MRI ultrasound analysis will help make the differential diagnosis. © 2014 S. Karger AG, Basel.

ONERC. Observatoire National sur les Effets du Rechauffement Climatique (National Observatory of Climate warming effects). Report to the Prime Minister and to Parliament. Climate changes and public health risks in France; Changements climatiques et risques sanitaires en France. Rapport au Premier Ministre et au Parlement

Energy Technology Data Exchange (ETDEWEB)

NONE

2010-07-01

After having recalled the climate change context and the activities of the ONERC (the French National Observatory of Climate Warming Effects) since its previous report, this report gathers several contributions by as many scientists. They propose analysis, comments and discussions on various topics: human diseases which might be influenced by climate change in France (heat waves and allergies, emergence of animal and human diseases, potential impacts of climate change on vector-borne diseases, infectious diseases in overseas territories, public health consequences), surveillance and health alert systems (infectious disease national surveillance and monitoring network, emergency response, satellite imagery, public health and risk management, lessons learned from the chikungunya pandemic), public health and risk management (overview of international works on the relationship between climate change and public health, public health consequences of climate change)

Pituitary-adrenocortical adjustments to transport stress in horses with previous different handling and transport conditions

Directory of Open Access Journals (Sweden)

E. Fazio

2016-08-01

Full Text Available Aim: The changes of the hypothalamic pituitary adrenal (HPA axis response to a long distance transportation results in increase of adrenocorticotropic hormone (ACTH and cortisol levels. The purpose of the study was to quantify the level of short-term road transport stress on circulating ACTH and cortisol concentrations, related to the effect of previous handling and transport experience of horses. Materials and Methods: The study was performed on 56 healthy horses after short-term road transport of 30 km. The horses were divided into four groups, Groups A, B, C, and D, with respect to the handling quality: Good (Groups A and B, bad (Group D, and minimal handling (Group C conditions. According to the previous transport, experience horses were divided as follows: Horses of Groups A and D had been experienced long-distance transportation before; horses of Groups B and C had been limited experience of transportation. Results: One-way RM-ANOVA showed significant effects of transport on ACTH changes in Groups B and C and on cortisol changes in both Groups A and B. Groups A and B showed lower baseline ACTH and cortisol values than Groups C and D; Groups A and B showed lower post-transport ACTH values than Groups C and D. Groups A, B, and C showed lower post-transport cortisol values than Group D. Only Groups A and B horses have shown an adequate capacity of stress response to transportation. Conclusion: The previous transport experience and quality of handling could influence the HPA axis physiological responses of horses after short-term road transport.

Characterization of Change and Significance for Clinical Findings in Radiology Reports Through Natural Language Processing.

Science.gov (United States)

Hassanpour, Saeed; Bay, Graham; Langlotz, Curtis P

2017-06-01

We built a natural language processing (NLP) method to automatically extract clinical findings in radiology reports and characterize their level of change and significance according to a radiology-specific information model. We utilized a combination of machine learning and rule-based approaches for this purpose. Our method is unique in capturing different features and levels of abstractions at surface, entity, and discourse levels in text analysis. This combination has enabled us to recognize the underlying semantics of radiology report narratives for this task. We evaluated our method on radiology reports from four major healthcare organizations. Our evaluation showed the efficacy of our method in highlighting important changes (accuracy 99.2%, precision 96.3%, recall 93.5%, and F1 score 94.7%) and identifying significant observations (accuracy 75.8%, precision 75.2%, recall 75.7%, and F1 score 75.3%) to characterize radiology reports. This method can help clinicians quickly understand the key observations in radiology reports and facilitate clinical decision support, review prioritization, and disease surveillance.

Denmark's National Inventory Report - Submitted under the United Nations Framework Convention on Climate Change, 1990-2001

DEFF Research Database (Denmark)

Illerup, J. B.; Lyck, E.; Nielsen, M.

This report is Denmark's National Inventory Report reported to the Conference of the Parties under the United Nations Framework Convention on Climate Change (UNFCCC) due by 15 April 2003. The report contains information on Denmark's in-ventories for all years' from 1990 to 2001 for CO2, CH4, N2O......, CO, NMVOC, SO2 , HFCs, PFCs and SF6....

The influence of previous low back trouble, general health, and working conditions on future sick-listing because of low back trouble. A 15-year follow-up study of risk indicators for self-reported sick-listing caused by low back trouble.

Science.gov (United States)

Müller, C F; Monrad, T; Biering-Sørensen, F; Darre, E; Deis, A; Kryger, P

1999-08-01

A 15-year follow-up study. To find risk indicators for self-reported sick-listing because of low back trouble and to evaluate which variables were the most important indicators of work incapacity resulting from low back trouble during the follow-up period of 15 years. The initial data were obtained from a health survey conducted in a general population from the Municipality of Glostrup, Denmark. The follow-up data included information from the Central Person Register, the Early Retirement Pension Register, and a postal questionnaire regarding self-reported sick-listing because of low back trouble. An epidemiologic study, in which logistic regression analyses were used for evaluation of the data. The model used consisted of the variable in question, age, gender, and previous experience of low back trouble, along with interactions. It was found that 22 of 37 variables were risk indicators for later self-reported sick-listing because of low back trouble during the preceding year or the 7 years before the date of follow-up evaluation. In analyzing the most significant variables simultaneously, it was found that information from the initial investigation about sick-listing in general during the previous 10 years, sciatic pain, use of analgesics for low back trouble, previous sick-listing because of low back trouble, and occupation were the most important risk indicators for self-reported work incapacity resulting from low back trouble during the follow-up period of 15 years. Findings showed that the strongest prognostic indicators of later sick-listing because of low back trouble involve information from the person about previous sick-listing behavior in general and previous experience of low back trouble episodes, especially if these had been accompanied by sciatic pain, use of analgesics, or previous low back trouble sick-listing.

Chemical changes in silver carp (Hypophthalmichthys molitrix) minced muscle during frozen storage: Effect of a previous washing process

Energy Technology Data Exchange (ETDEWEB)

Asgharzadeh, A.; Shabanpour, B.; Aubourg, S. P.; Hosseini, H.

2010-07-01

previous washing process Silver carp (Hypophthalmichthys molitrix) has acquired great attention because of its increasing farming production and application in the surimi-product commercialization. This work focuses on the effect of a washing process followed by frozen storage (6 months; -18 degree centigrade) on the quality of minced silver carp muscle. A previous washing step has led to a positive effect on fish quality according to marked content decreases in expressible moisture, volatile amines, free fatty acids and thiobarbituric acid reactive substances; such quality performances were maintained throughout the frozen storage. On the other hand, most indexes tested showed quality losses throughout the frozen storage in both washed and unwashed fish material; however, water holding capacity (WHC) remained unchanged in washed fish throughout the frozen storage. Among quality indexes, a special attention should be given to the expressible moisture value and accordingly the WHC, as being closely related to the gel forming ability in order to obtain surimi-type commercial products. (Author) 46 refs.

Relationship of deer and moose populations to previous winters' snow

Science.gov (United States)

Mech, L.D.; McRoberts, R.E.; Peterson, R.O.; Page, R.E.

1987-01-01

(1) Linear regression was used to relate snow accumulation during single and consecutive winters with white-tailed deer (Odocoileus virginianus) fawn:doe ratios, mosse (Alces alces) twinning rates and calf:cow ratios, and annual changes in deer and moose populations. Significant relationships were found between snow accumulation during individual winters and these dependent variables during the following year. However, the strongest relationships were between the dependent variables and the sums of the snow accumulations over the previous three winters. The percentage of the variability explained was 36 to 51. (2) Significant relationships were also found between winter vulnerability of moose calves and the sum of the snow accumulations in the current, and up to seven previous, winters, with about 49% of the variability explained. (3) No relationship was found between wolf numbers and the above dependent variables. (4) These relationships imply that winter influences on maternal nutrition can accumulate for several years and that this cumulative effect strongly determines fecundity and/or calf and fawn survivability. Although wolf (Canis lupus L.) predation is the main direct mortality agent on fawns and calves, wolf density itself appears to be secondary to winter weather in influencing the deer and moose populations.

Potential climate change impacts and the BLM Rio Puerco field office's transportation system : a technical report

Science.gov (United States)

2015-03-01

This report provides information about potential climate change impacts in central New Mexico and their possible implications for the Bureau of Land Management (BLM) Rio Puerco Field Office (RPFO) transportation network. The report considers existing...

Renewable energy sources and climate change mitigation. Special report of the Intergovernmental Panel on Climate Change (IPCC)

Energy Technology Data Exchange (ETDEWEB)

Edenhofer, O. (Potsdam Institute for Climate Impact Research (PIK), Potsdam (Germany)); Pichs Madruga, R. (Centro de Investigaciones de la Economia Mundial (CIEM), Hanoi (Viet Nam)); Sokona, Y. (African Climate Policy Centre, United Nations Economic Commission for Africa, Addis Ababa (Ethiopia)) (and others)

2012-07-01

Climate change is one of the great challenges of the 21st century. Its most severe impacts may still be avoided if efforts are made to transform current energy systems. Renewable energy sources have a large potential to displace emissions of greenhouse gases from the combustion of fossil fuels and thereby to mitigate climate change. If implemented properly, renewable energy sources can contribute to social and economic development, to energy access, to a secure and sustainable energy supply, and to a reduction of negative impacts of energy provision on the environment and human health. This Special Report on Renewable Energy Sources and Climate Change Mitigation (SRREN) impartially assesses the scientific literature on the potential role of renewable energy in the mitigation of climate change for policymakers, the private sector, academic researchers and civil society. It covers six renewable energy sources - bioenergy, direct solar energy, geothermal energy, hydropower, ocean energy and wind energy - as well as their integration into present and future energy systems. It considers the environmental and social consequences associated with the deployment of these technologies, and presents strategies to overcome technical as well as non-technical obstacles to their application and diffusion. The authors also compare the levelized cost of energy from renewable energy sources to recent non-renewable energy costs. (Author)

Effects of Climate Change on Federal Hydropower. Report to Congress

Energy Technology Data Exchange (ETDEWEB)

None

2013-08-01

This is a formal Department of Energy report to Congress. It outlines the findings of an assessment directed by Congress in Section 9505 of the SECURE Water Act of 2009 (Public Law 111-11), the US Department of Energy (DOE), in consultation with the federal Power Marketing Administrations (PMAs) and other federal agencies, including federal dam owners, has prepared a comprehensive assessment examining the effects of climate change on water available for hydropower at federal facilities and on the marketing of power from these federal facilities.

Ultrastructural changes in tumor cells following boron neutron capture therapy

International Nuclear Information System (INIS)

Barkla, D.H.; Brown, J.K.; Meriaty, H.; Allen, B.J.

1992-01-01

In a previous study the authors reported on morphological changes in two human melanoma cell lines treated with 10 B-phenylalanine(BPA) and Boron Neutron Capture Therapy(BNCT). The present study describes morphological changes in melanoma and glioma cell lines treated with boron-tetraphenyl porphyrin(BTPP) and BNCT. Porphyrin compounds are selectively taken up by tumor cells and have been used clinically in phototherapy treatment of cancer patients. Boronated porphyrins show good potential as therapeutic agents in BNCT treatment of human cancer patients

Educational Imperatives for Oral Health Personnel: Change or Decay? Report of a WHO Expert Committee. Technical Report Series 794.

Science.gov (United States)

World Health Organization, Geneva (Switzerland).

This report highlights trends in disease patterns and technological advances that call for sweeping changes in the education of oral health personnel. It first provides a brief history of the development of dental education. The second and most extensive section analyzes global trends for dental caries, periodontal conditions, tooth loss and…

The economic impacts of climate change on the Chilean agricultural sector: A non-linear agricultural supply model

Directory of Open Access Journals (Sweden)

Roberto Ponce

2014-12-01

Full Text Available Agriculture could be one of the most vulnerable economic sectors to the impacts of climate change in the coming decades, with impacts threatening agricultural production in general and food security in particular. Within this context, climate change will impose a challenge to policy makers, especially in those countries that based their development on primary sectors. In this paper we present a non-linear agricultural supply model for the analysis of the economic impacts of changes in crop yields due to climate change. The model accounts for uncertainty through the use of Monte Carlo simulations about crop yields. According to our results, climate change impacts on the Chilean agricultural sector are widespread, with considerable distributional consequences across regions, and with fruits producers being worst-off than crops producers. In general, the results reported here are consistent with those reported by previous studies showing large economic impacts on the northern zone. However, our model does not simulate remarkable economic consequences at the country level as previous studies did.

Acidic deposition: State of science and technology. Report 11. Historical changes in surface-water acid-base chemistry in response to acidic deposition. Final report

International Nuclear Information System (INIS)

Sullivan, T.J.; Small, M.J.; Kingston, J.C.; Bernert, J.A.; Thomas, D.R.

1990-09-01

The objectives of the analyses reported in the State of Science report are to: identify the lake and stream populations in the United States that have experienced chronic changes in biologically significant constituents of surface water chemistry (e.g. pH, Al) in response to acidic deposition; quantify biologically meaningful historical changes in chronic surface water chemistry associated with acidic deposition, with emphasis on ANC, pH, and Al; estimate the proportion of lakes nor acidic that were not acidic in pre-industrial times; estimate the proportional response of each of the major chemical constituents that have changed in response to acidic deposition using a subset of statistically selected Adirondack lakes for which paleolimnological reconstructions of pre-industrial surface water chemistry have been performed; evaluate and improve, where appropriate and feasible, empirical models of predicting changes in ANC; and evaluate the response of seepage lakes to acidic deposition

Overseas territories facing the challenge of climate change - Report to the Prime Minister and to the Parliament

International Nuclear Information System (INIS)

Verges, Paul; Galliot, Michel; Mondon, Sylvain; Reysset, Bertrand; Zilli, Dario; Bourcier, Vincent; Duvernoy, Jerome; Omarjee, Younous; Duvat, Virginie; Mossot, Gabrielle; Magnan, Alexandre; Allenbach, Michel; Bocquet, Aurelie; Bonnardot, Francois; Dandin, Philippe; Palany, Philippe; Pontaud, Marc; Porcher, Michel; Delalande, Daniel

2012-12-01

This report identifies the social-environmental challenges associated with climate change for French overseas territories, proposes an analysis of the impact of activities of the different economic sectors on the environment, and proposes some principles for action. After an introduction which outlines the importance of addressing climate change and adaptation, and describes the situation of French overseas territories in front of climate change, a first part identifies and discusses the main social-environmental challenges associated with climate change (climate evolution, role of climate change in a context of economic development, the territory as a resource system, climate change considered as an impact chain, the relative weight of climatic uncertainties). Then, the report analyses the potential impacts of climate change on biodiversity, on tourism, on fishing and aquaculture, on agriculture and breeding, on forestry, on health, and on the energy sector. For each of them, the economic weight is indicated and commented, expected impacts are discussed, and adaptation possibilities and implementation modalities are commented. The issue of coastal planning and risks related to climate change is also addressed

Gastrointestinal tolerability with ibandronate after previous weekly bisphosphonate treatment.

Science.gov (United States)

Derman, Richard; Kohles, Joseph D; Babbitt, Ann

2009-01-01

Data from two open-label trials (PRIOR and CURRENT) of women with postmenopausal osteoporosis or osteopenia were evaluated to assess whether monthly oral and quarterly intravenous (IV) ibandronate dosing improved self-reported gastrointestinal (GI) tolerability for patients who had previously experienced GI irritation with bisphosphonate (BP) use. In PRIOR, women who had discontinued daily or weekly BP treatment due to GI intolerance received monthly oral or quarterly IV ibandronate for 12 months. The CURRENT subanalysis included women receiving weekly BP treatment who switched to monthly oral ibandronate for six months. GI symptom severity and frequency were assessed using the Osteoporosis Patient Satisfaction Questionnaire. In PRIOR, mean GI tolerability scores increased significantly at month 1 from screening for both treatment groups (oral: 79.3 versus 54.1; IV: 84.4 versus 51.0; p 90% at Month 10). In the CURRENT subanalysis >60% of patients reported improvements in heartburn or acid reflux and >70% indicated improvement in other stomach upset at month 6. Postmenopausal women with GI irritability with daily or weekly BPs experienced improvement in symptoms with extended dosing monthly or quarterly ibandronate compared with baseline.

Denmark's National Inventory Reports. Submitted under the United Nations framework convention on climate change

Energy Technology Data Exchange (ETDEWEB)

Boll Illerup, J.; Lyck, E.; Winther, M. [Danmarks Miljoeundersoegelser, Afd. for Systemanalyse (Denmark); Rasmussen, E. [Energistyrelsen (Denmark)

2000-05-01

This report is Denmark's National Inventory Report reported to the Conference of the Parties under the United Nations Framework Convention on Climate Change (UNFCCC) due by 15 April 2000. The report contains information on Denmark's inventories for all years from 1990 to 1998 for CO{sub 2}, CH{sub 4}, N{sub 2}O, NO{sub x}, CO, NMVOC, SO{sub 2}, HFCs, PFCs and SF. (au)

Integrating sustainable development into the Fourth Assessment Report of the Intergovernmental Panel on Climate Change

International Nuclear Information System (INIS)

Najam, Adil; Rahman, Atiq A.; Huq, Saleemul; Sokona, Youba

2003-01-01

This paper reviews how sustainable development was treated in prior assessment reports of the Intergovernmental Panel on Climate Change (IPCC) and presents proposals on how it might be integrated into the forthcoming Fourth Assessment Report (AR4). There has been a steady, but slow, increase in the exposure and treatment of sustainable development in each subsequent IPCC assessment. However, much more remains to be done if the mandate provided in the United Nations Framework Convention on Climate Change (UNFCCC) is to be met. The paper argues that the AR4 can take three practical steps in making the integration more complete. First, at the conceptual level, equity concerns should be made a more pervasive, even central, focus of the AR4. Second, at the analytical level, the examination of alternative development pathways begun during the TAR process needs to be continued and expanded. Third, at the operational level, the AR4 should deal with sustainable development in all its chapters rather than relegating it to a peripheral few, should broaden the base of expertise reflected in its panels of authors and reviewers, and should commission a companion special report on climate change and sustainable development

Influence of previous administration of trans-phenylcyclopropylamine on radioprotective and hypothermic effects of serotonin

International Nuclear Information System (INIS)

Misustova, J.; Hosek, B.; Novak, L.; Kautska, J.

1978-01-01

The influence of a previous administration of trans-phenylcyclopropylamine (t-PCPA) on radioprotective and hypothermic effects of serotonin was studied in male mice of the H strain, which were given t-PCPA in the dose of 4 mg/kg intraperitoneally 2 or 7 hours before application of serotonin (40 mg/kg, i.p.). The time course of protection was studied for exposures to 800 and 900 R. The results have shown that a previous administration of t-PCPA does not alter the short-time protective effect of serotonin, but that it significantly prolongs the time course of protection. The administration of t-PCPA also affects the starting speed and the duration of the serotonin-induced hypothermic reaction. The established correlation between prolongation of the radioprotective and hypothermic effects of serotonin induced by previous application of t-PCPA supplements the results with the existence of mutual relationship between changes of the energetic exchange and radioresistance of the organism. (author)

Behaviour change interventions to influence antimicrobial prescribing: a cross-sectional analysis of reports from UK state-of-the-art scientific conferences.

Science.gov (United States)

Rawson, T M; Moore, L S P; Tivey, A M; Tsao, A; Gilchrist, M; Charani, E; Holmes, A H

2017-01-01

To improve the quality of antimicrobial stewardship (AMS) interventions the application of behavioural sciences supported by multidisciplinary collaboration has been recommended. We analysed major UK scientific research conferences to investigate AMS behaviour change intervention reporting. Leading UK 2015 scientific conference abstracts for 30 clinical specialties were identified and interrogated. All AMS and/or antimicrobial resistance(AMR) abstracts were identified using validated search criteria. Abstracts were independently reviewed by four researchers with reported behavioural interventions classified using a behaviour change taxonomy. Conferences ran for 110 days with >57,000 delegates. 311/12,313(2.5%) AMS-AMR abstracts (oral and poster) were identified. 118/311(40%) were presented at the UK's infectious diseases/microbiology conference. 56/311(18%) AMS-AMR abstracts described behaviour change interventions. These were identified across 12/30(40%) conferences. The commonest abstract reporting behaviour change interventions were quality improvement projects [44/56 (79%)]. In total 71 unique behaviour change functions were identified. Policy categories; "guidelines" (16/71) and "service provision" (11/71) were the most frequently reported. Intervention functions; "education" (6/71), "persuasion" (7/71), and "enablement" (9/71) were also common. Only infection and primary care conferences reported studies that contained multiple behaviour change interventions. The remaining 10 specialties tended to report a narrow range of interventions focusing on "guidelines" and "enablement". Despite the benefits of behaviour change interventions on antimicrobial prescribing, very few AMS-AMR studies reported implementing them in 2015. AMS interventions must focus on promoting behaviour change towards antimicrobial prescribing. Greater focus must be placed on non-infection specialties to engage with the issue of behaviour change towards antimicrobial use.

Fourth annual report 1991

International Nuclear Information System (INIS)

1991-01-01

The Independent Radiation Monitoring Scheme for Clwyd began its monitoring programme in Clwyd in 1988. This is the fourth report on the results of the radiation monitoring carried out within Clwyd. The historical reasons for the conception of the Radiation Monitoring Scheme are given in the First Annual Report together with the protocol of operation and detailed sampling and monitoring information. The fourth Annual Report identifies any changes in techniques that have occurred in the last twelve months together with the latest monitoring and analytical data. Samples of air, beach materials, coastal sand and silt, seaweed, meat, fish and milk were taken from various locations within the county. No significant charges in radiation levels were found when compared with data from previous years. The values have remained within the range currently being expected throughout the United Kingdom. (author)

Bias versus bias: harnessing hindsight to reveal paranormal belief change beyond demand characteristics.

Science.gov (United States)

Kane, Michael J; Core, Tammy J; Hunt, R Reed

2010-04-01

Psychological change is difficult to assess, in part because self-reported beliefs and attitudes may be biased or distorted. The present study probed belief change, in an educational context, by using the hindsight bias to counter another bias that generally plagues assessment of subjective change. Although research has indicated that skepticism courses reduce paranormal beliefs, those findings may reflect demand characteristics (biases toward desired, skeptical responses). Our hindsight-bias procedure circumvented demand by asking students, following semester-long skepticism (and control) courses, to recall their precourse levels of paranormal belief. People typically remember themselves as previously thinking, believing, and acting as they do now, so current skepticism should provoke false recollections of previous skepticism. Given true belief change, therefore, skepticism students should have remembered themselves as having been more skeptical than they were. They did, at least about paranormal topics that were covered most extensively in the course. Our findings thus show hindsight to be useful in evaluating cognitive change beyond demand characteristics.

Changes on diffusion-weighted MRI with focal motor status epilepticus: case report

International Nuclear Information System (INIS)

Loevblad, K.O.; Senn, P.; Zutter, D.; Bassetti, C.; Donati, F.; Loevblad, K.O.; Zeller, O.; Schroth, G.

2003-01-01

Transient imaging abnormalities, including changes on diffusion-weighted imaging (DWI), may be seen in focal status epilepticus. The changes on DWI provide an insight into the pathophysiology. We report a 53-year-old man with focal motor status epilepticus involving the left hand, arm and face with focal slowing on EEG. The apparent diffusion coefficients (ADC) were higher in the affected hemisphere than on the other side. At 10 days and 6 weeks after the end of the seizures, we saw normal ADCs and atrophy of the affected hemisphere. We conclude that the MRI findings indicate both cytotoxic and vasogenic oedema during seizure activity and subsequent loss of brain parenchyma. (orig.)

Changes on diffusion-weighted MRI with focal motor status epilepticus: case report

Energy Technology Data Exchange (ETDEWEB)

Loevblad, K O [Neuroradiology, Radiodiagnostic, Hopital Cantonal de Geneve HUG, Geneve (Switzerland); Senn, P; Zutter, D; Bassetti, C; Donati, F [Dept. of Neurology, Inselspital, Univ. Hospital, Berne (Switzerland); Loevblad, K O; Zeller, O; Schroth, G [Div. of Neuroradiology, Inselspital, Univ. Hospital, Berne (Switzerland)

2003-04-01

Transient imaging abnormalities, including changes on diffusion-weighted imaging (DWI), may be seen in focal status epilepticus. The changes on DWI provide an insight into the pathophysiology. We report a 53-year-old man with focal motor status epilepticus involving the left hand, arm and face with focal slowing on EEG. The apparent diffusion coefficients (ADC) were higher in the affected hemisphere than on the other side. At 10 days and 6 weeks after the end of the seizures, we saw normal ADCs and atrophy of the affected hemisphere. We conclude that the MRI findings indicate both cytotoxic and vasogenic oedema during seizure activity and subsequent loss of brain parenchyma. (orig.)

INTRODUCTION Previous reports have documented a high ...

African Journals Online (AJOL)

Conclusion: The positive effect of education on oral hygiene practices is highlighted in this study. However there is still need for proper health enlightenment in this population with regards to use of the available oral health care facilities. Keywords: Oral hygiene, Pregnancy, Nigeria. Annals of Ibadan Postgraduate Medicine.

National Institute for Global Environmental Change. Final Technical Report 1990-2007

Energy Technology Data Exchange (ETDEWEB)

Athanasios Toulopoulos

2007-11-01

Research conducted by the six NIGEC Regional Centers during recent years is reported. An overview of the NIGEC program from its beginnings provides a description and evaluation of the program's vision, strategy and major accomplishments. The program's purpose was to support academic research on environmental change in regions of the country that had historically received relatively little federal funding. The overall vision of NIGEC may be stated as the performance of academic research on the regional interactions between ecosystems and climate. NIGEC's research presents important evidence on the impacts of climate variability and change, and in some cases adaptability, for a broad range of both managed and unmanaged ecosystems, and has thereby documented significant regional issues on the environmental responses to climate change. NIGEC's research has demonstrated large regional differences in the atmospheric carbon exchange budgets of croplands and forests, that there are significant variations of this exchange on diurnal, synoptic, seasonal and interannual time scales due to atmospheric variability (including temperature, precipitation and cloudiness), and that management practices and past history have predominant effects in grasslands and croplands. It is the mid-latitude forests, however, that have received more attention in NIGEC than any other specific ecosystem, and NIGEC's initiation of and participation in the AmeriFlux program, network of carbon flux measurement sites in North American old-growth forests, is generally considered to be its most significant single accomplishment. By including appendices with complete listings of NIGEC publications, principal investigators and participating institutions, this report may also serve as a useful comprehensive documentation of NIGEC.

49 CFR 173.23 - Previously authorized packaging.

Science.gov (United States)

2010-10-01

... 49 Transportation 2 2010-10-01 2010-10-01 false Previously authorized packaging. 173.23 Section... REQUIREMENTS FOR SHIPMENTS AND PACKAGINGS Preparation of Hazardous Materials for Transportation § 173.23 Previously authorized packaging. (a) When the regulations specify a packaging with a specification marking...

Reporting behaviour change interventions: do the behaviour change technique taxonomy v1, and training in its use, improve the quality of intervention descriptions?

Science.gov (United States)

Wood, Caroline E; Hardeman, Wendy; Johnston, Marie; Francis, Jill; Abraham, Charles; Michie, Susan

2016-06-07

Behaviour change interventions are likely to be reproducible only if reported clearly. We assessed whether the behaviour change technique taxonomy version 1 (BCTTv1), with and without training in identifying BCTs, improves the clarity and replicability of written reports of observed behaviour change interventions. Three studies assessed effects of using and training in the use of BCTTv1 on the clarity and replicability of intervention descriptions written after observing videos of smoking cessation interventions. Study 1 examined the effects of using and not using BCTTv1. Study 2 examined the effects of using BCTTv1 and training in use of BCTTv1 compared no use and no training. Study 3 employed a within-group design to assess change in descriptions written before and after training. One-hundred and 66 'writers' watched videos of behaviour change interventions and wrote descriptions of the active components delivered. In all studies, the participants' written descriptions were evaluated by (i) 12 'raters' (untrained in BCTTv1) for clarity and replicability and (ii) 12 'coders' (trained in BCTTv1) for reliability of BCT coding. Writers rated the usability and accessibility of using BCTTv1 to write descriptions. Ratings of clarity and replicability did not differ between groups in study 1 (all ps > 0.05), were poorer for trained users in study 2 (all ps < 0.01) and improved following training in study 3 (all ps < 0.05). BCT identification was more reliable from descriptions written by trained BCTTv1 users (p < 0.05; study 2) but not simple use of BCTTv1 (p = 0.93; study 1) or by writers who had written a description without BCTTv1, before training (p = 0.50; study 3). Writers reported that using BCTTv1 was difficult but 'useful', 'good' and 'desirable' and that their descriptions would be clear and replicable (all means above mid-point of the scale). Effects of training to use BCTTv1 on the quality of written reports of observed interventions

Analysis of over 10,000 Cases finds no association between previously reported candidate polymorphisms and ovarian cancer outcome

DEFF Research Database (Denmark)

White, Kristin L; Vierkant, Robert A; Fogarty, Zachary C

2013-01-01

Ovarian cancer is a leading cause of cancer-related death among women. In an effort to understand contributors to disease outcome, we evaluated single-nucleotide polymorphisms (SNP) previously associated with ovarian cancer recurrence or survival, specifically in angiogenesis, inflammation, mitosis...

22 CFR 40.91 - Certain aliens previously removed.

Science.gov (United States)

2010-04-01

... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Certain aliens previously removed. 40.91... IMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Aliens Previously Removed § 40.91 Certain aliens previously removed. (a) 5-year bar. An alien who has been found inadmissible, whether as a result...

Climate change on Twitter: topics, communities and conversations about the 2013 IPCC Working Group 1 report

NARCIS (Netherlands)

Pearce, W; Holmberg, K; Hellsten, I.; Nerlich, B.

2014-01-01

In September 2013 the Intergovernmental Panel on Climate Change published its Working Group 1 report, the first comprehensive assessment of physical climate science in six years, constituting a critical event in the societal debate about climate change. This paper analyses the nature of this debate

The Adaptation Gap Report. Towards Global Assessment

DEFF Research Database (Denmark)

2017-01-01

The Paris Agreement, adopted in 2015, established the global goal on adaptation of enhancing adaptive capacity, strengthening resilience and reducing vulnerability to climate change, with a view to contributing to sustainable development and ensuring an adequate adaptation response in the context...... Change (UNFCCC) to prepare for the implementation of the Paris Agreement. In contrast to previous Adaptation Gap Reports, the 2017 report focuses on issues relating to frameworks, comprising concepts, methodologies and data, rather than on assessing a particular dimension of the adaptation gap. Future...... extensive external review. The Paris Agreement’s global goal on adaptation provides a new starting point and impetus for assessing progress on adaptation at the global level, but additional information is required for assessing such progress. The global goal on adaptation provides a collective vision...

Differences between previously married and never married 'gay' men: family background, childhood experiences and current attitudes.

Science.gov (United States)

Higgins, Daryl J

2004-01-01

Despite a large body of literature on the development of sexual orientation, little is known about why some gay men have been (or remain) married to a woman. In the current study, a self-selected sample of 43 never married gay men ('never married') and 26 gay men who were married to a woman ('previously married') completed a self-report questionnaire. Hypotheses were based on five possible explanations for gay men's marriages: (a) differences in sexual orientation (i.e., bisexuality); (b) internalized homophobia; (c) religious intolerance; (d) confusion created because of childhood/adolescent sexual experiences; and/or (e) poor psychological adjustment. Previously married described their families' religious beliefs as more fundamentalist than never married. No differences were found between married' and never married' ratings of their sexual orientation and identity, and levels of homophobia and self-depreciation. Family adaptability and family cohesion and the degree to which respondents reported having experienced child maltreatment did not distinguish between previously married and never married. The results highlight how little is understood of the reasons why gay men marry, and the need to develop an adequate theoretical model.

A systematic review of patient reported factors associated with uptake and completion of cardiovascular lifestyle behaviour change

Directory of Open Access Journals (Sweden)

Murray Jenni

2012-12-01

Full Text Available Abstract Background Healthy lifestyles are an important facet of cardiovascular risk management. Unfortunately many individuals fail to engage with lifestyle change programmes. There are many factors that patients report as influencing their decisions about initiating lifestyle change. This is challenging for health care professionals who may lack the skills and time to address a broad range of barriers to lifestyle behaviour. Guidance on which factors to focus on during lifestyle consultations may assist healthcare professionals to hone their skills and knowledge leading to more productive patient interactions with ultimately better uptake of lifestyle behaviour change support. The aim of our study was to clarify which influences reported by patients predict uptake and completion of formal lifestyle change programmes. Methods A systematic narrative review of quantitative observational studies reporting factors (influences associated with uptake and completion of lifestyle behaviour change programmes. Quantitative observational studies involving patients at high risk of cardiovascular events were identified through electronic searching and screened against pre-defined selection criteria. Factors were extracted and organised into an existing qualitative framework. Results 374 factors were extracted from 32 studies. Factors most consistently associated with uptake of lifestyle change related to support from family and friends, transport and other costs, and beliefs about the causes of illness and lifestyle change. Depression and anxiety also appear to influence uptake as well as completion. Many factors show inconsistent patterns with respect to uptake and completion of lifestyle change programmes. Conclusion There are a small number of factors that consistently appear to influence uptake and completion of cardiovascular lifestyle behaviour change. These factors could be considered during patient consultations to promote a tailored approach to

Changing your mind.

Science.gov (United States)

Walsh, Clare R; Johnson-Laird, P N

2009-07-01

When individuals detect an inconsistency in a set of propositions, they tend to change their minds about at least one proposition to resolve the inconsistency. The orthodox view from William James (1907) onward has been that a rational change should be minimal. We propose an alternative hypothesis according to which individuals seek to resolve inconsistencies by explaining their origins. We report four experiments corroborating the explanatory hypothesis. Experiment 1 showed that participants' explanations revised general conditional claims rather than specific categorical propositions. Experiment 2 showed that, when explanations did revise the categorical proposition, participants also tended to deny the consequences of a second generalization. Experiment 3 showed that this tendency persists when participants previously affirmed these consequences explicitly. Experiment 4 showed that, when participants could easily explain an inconsistency by revising a generalization, they were more likely to accept the consequences of a second generalization. All four results contravene minimalism but support the explanatory hypothesis.

Wolff-Parkinson-White syndrome with cleft lip and palate: A rare, previously unreported association

Directory of Open Access Journals (Sweden)

K Kannan

2008-01-01

Full Text Available Wolff-Parkinson-White syndrome, also called Pre Excitation Syndrome, is characterized by an extra pathway that conducts the electrical impulses from the atria to the ventricles without the normal delay. We are reporting a case of WPW syndrome with a cleft lip and palate, which is a rare association and previously unreported in literature.

The second Swedish national report on climate changes. Under the United Nations framework convention on climate change

International Nuclear Information System (INIS)

Anon.

1997-01-01

The Swedish policy and measures for mitigating the climatic change and an inventory of Swedish greenhouse gas emissions are reported. 80% of these emission are carbon dioxide, and the transport sector is responsible for 33% of the emissions. Emissions from the energy sector and industry have been reduced, while the emissions from transports are increasing. The Swedish forests are a carbon sink, with a net accumulation of about 30 M tons/year, which roughly corresponds to half the emission of carbon dioxide from fossil fuels

The Relationship of Lumbar Multifidus Muscle Morphology to Previous, Current, and Future Low Back Pain

DEFF Research Database (Denmark)

Hebert, Jeffrey J; Kjær, Per; Fritz, Julie M

2014-01-01

of LBP after five and nine years.Summary of Background Data. Although low back pain (LBP) is a major source of disease burden, the biologic determinants of LBP are poorly understood.Methods. Participants were 40-year-old adults randomly sampled from a Danish population and followed-up at ages 45 and 49....... At each time point, participants underwent magnetic resonance imaging and reported ever having had LBP, LBP in the previous year, non-trivial LBP in the previous year, or a history of pain radiating into the legs. Pixel intensity and frequencies from T1-weighted magnetic resonance images identified...

Previous experience in manned space flight: A survey of human factors lessons learned

Science.gov (United States)

Chandlee, George O.; Woolford, Barbara

1993-01-01

Previous experience in manned space flight programs can be used to compile a data base of human factors lessons learned for the purpose of developing aids in the future design of inhabited spacecraft. The objectives are to gather information available from relevant sources, to develop a taxonomy of human factors data, and to produce a data base that can be used in the future for those people involved in the design of manned spacecraft operations. A study is currently underway at the Johnson Space Center with the objective of compiling, classifying, and summarizing relevant human factors data bearing on the lessons learned from previous manned space flights. The research reported defines sources of data, methods for collection, and proposes a classification for human factors data that may be a model for other human factors disciplines.

Annual report 2003

International Nuclear Information System (INIS)

2004-01-01

The annual report of SE, a. s., contains information for the year of 2003 and summarises SE's most important financial data for the stated period. The joint stock company Slovenske elektrarne, a. s. (Slovak Power Plants) was established on January 21, 2002, when it was entered into the Commercial Register as a new business entity formed by splitting the former Slovenska elektrarne, a. s. (SE, a. s.) into three independent business entities: Slovenska elektrarne, a. s. (SE, a. s.), Slovenska elektrizacna prenosova sustava, a. s. (Slovak Transmission Grid), and Teplaren Kosice, a. s. (Heating Plant Kosice). Data regarding electricity and heat generation and operational and financial results of the company are stated for the year of 2003, without providing a comparison to the previous year. The reason is that 2002 data do not cover the whole year, as the new SE a. s. was established on January 21, 2002 with changed mix of heat and electricity generation assets. Comparison data for previous years are provided only for certain technical parameters regarding nuclear safety, environment and human resources. This report contains the following headings: (1) SE Board of directors; (2) Supervisory Board; (3) Address by the Chairman of the Board of directors; (4) Year in brief; (5) Organisational structure of the company; (6) Participating interests held by the company; (7) Company strategy; (8) Heat and electricity generation; (9) Sales of electricity, ancillary services and heat; (10) Investments; (11) International cooperation; (12) Nuclear safety; (13) Environment; (14) Human resources; (15) Business report and financial statements; (16) Auditor's report; (17) List of abbreviations

How emotional media reports influence attitude formation and change: the interplay of attitude base, attitude certainty and persuasion

NARCIS (Netherlands)

Ryffel, F.A.; Wirz, D.S.; Kühne, R.; Wirth, W.

2014-01-01

This study examined the influence of an emotionally arousing writing style on attitude formation and change. It has been proposed that different writing styles induce attitudes based on either affect or cognition and with either high or low certainty. Previous work indicates that the interplay of

A rare case of failed healing in previously burned skin after a secondary burns.

Science.gov (United States)

Goldie, Stephen J; Parsons, Shaun; Menezes, Hana; Ives, Andrew; Cleland, Heather

2017-01-01

Patients presenting with large surface area burns are common in our practice; however, patients with a secondary large burn on pre-existing burn scars and grafts are rare and not reported. We report on an unusual case of a patient sustaining a secondary large burn to areas previously injured by a burn from a different mechanism. We discuss the potential implications when managing a case like this and suggest potential biological reasons why the skin may behave differently. Our patient was a 33-year-old man who presented with a 5% TBSA burn on skin scarred by a previous 40% total body surface area (TBSA) burn and skin grafts. Initially assessed as superficial partial thickness in depth, the wounds were treated conservatively with dressings; however, they failed to heal and became infected requiring surgical management. Burns sustained in areas of previous burn scars and grafts may behave differently to normal patterns of healing, requiring more aggressive management and surgical intervention at an early stage.

Changing patterns of brain activation during maze learning.

Science.gov (United States)

Van Horn, J D; Gold, J M; Esposito, G; Ostrem, J L; Mattay, V; Weinberger, D R; Berman, K F

1998-05-18

Recent research has found that patterns of brain activation involving the frontal cortex during novel task performance change dramatically following practice and repeat performance. Evidence for differential left vs. right frontal lobe activation, respectively, during episodic memory encoding and retrieval has also been reported. To examine these potentially related issues regional cerebral blood flow (rCBF) was measured in 15 normal volunteers using positron emission tomography (PET) during the naive and practiced performance of a maze task paradigm. SPM analysis indicated a largely right-sided, frontal lobe activation during naive performance. Following training and practice, performance of the same maze task elicited a more posterior pattern of rCBF activation involving posterior cingulate and precuneus. The change in the pattern of rCBF activation between novel and practiced task conditions agrees with results found in previous studies using repeat task methodology, and indicates that the neural circuitry required for encoding novel task information differs from that required when the same task has become familiar and information is being recalled. The right-sided preponderance of activation during naive performance may relate to task novelty and the spatially-based nature of the stimuli, whereas posterior areas activated during repeat performance are those previously found to be associated with visuospatial memory recall. Activation of these areas, however, does not agree with previously reported findings of left-sided activation during verbal episodic memory encoding and right-sided activation during retrieval, suggesting different neural substrates for verbal and visuospatial processing within memory. Copyright 1998 Elsevier Science B.V.

Micrococcus sedentarius bacteraemia presenting with haemophagocytic syndrome in previously healthy boy.

Science.gov (United States)

Kuskonmaz, Baris; Kara, Ates; Ozen, Maide; Cengiz, A Bülent; Ozen, Metehan; Seçmeer, Gülten; Gürgey, Aytemiz

2006-01-01

Haemophagocytic syndromes are the clinical manifestation of an increased macrophagic activity with haemophagocytosis. Infection-associated HS was originally described by Risdall in 1979, in viral disease. Since the initial description HS has also been documented in patients with bacterial, parasitic or fungal infections. We describe a case of Micrococcus sedentarius bacteraemia in a previously healthy 10-y-old boy with haemophagocytic syndrome. Species of micrococci are generally considered as non-pathogenic commensals that colonize the skin, mucosae and oropharynx. We report the first case of Microccoccus sedentarius bacteraemia in an immunocompetent host and first case of HS associated with Micrococcus species.

Previous Mental Disorders and Subsequent Onset of Chronic Back or Neck Pain : Findings From 19 Countries

NARCIS (Netherlands)

Viana, Maria Carmen; Lim, Carmen C W; Garcia Pereira, Flavia; Aguilar-Gaxiola, Sergio; Alonso, Jordi; Bruffaerts, Ronny; de Jonge, Peter; Caldas-de-Almeida, Jose Miguel; O'Neill, Siobhan; Stein, Dan J; Al-Hamzawi, Ali; Benjet, Corina; Cardoso, Graça; Florescu, Silvia; de Girolamo, Giovanni; Haro, Josep Maria; Hu, Chiyi; Kovess-Masfety, Viviane; Levinson, Daphna; Piazza, Marina; Posada-Villa, José; Rabczenko, Daniel; Kessler, Ronald C; Scott, Kate M

Associations between depression/anxiety and pain are well established, but its directionality is not clear. We examined the associations between temporally previous mental disorders and subsequent self-reported chronic back/neck pain onset, and investigated the variation in the strength of

The change of music preferences following the onset of a mental disorder

OpenAIRE

Stefan Gebhardt; Richard von Georgi

2015-01-01

A psychiatric population (n=123) was examined on how music preferences had changed after the onset of a mental disorder. Most patients did not change their previous music preference; this group of patients considered music helpful for their mental state, showed more attractivity and enforcement as personality traits and used music more for emotion modulation. Patients who experienced a preference shift reported that music had impaired them during the time of illness; these patients showed les...

3D Fourier synthesis of a new X-ray picture identical in projection to a previous picture

International Nuclear Information System (INIS)

Carlsson, P.E.

1993-01-01

A central problem in diagnostic radiology is to compare a new X-ray picture with a previous picture and from this comparison be able to decide if anatomical changes have occurred in the patient or not. It is of primary interest that these pictures are identical in projection. If not it is difficult to decide with confidence if differences between the pictures are due to anatomical changes or differences in their projection geometry. In this thesis we present a non invasive method that makes it possible to find the relative changes in the projection geometry between the exposure of a previous picture and a new picture. The method presented is based on the projection slice theorem (central section theorem). Instead of an elaborate search for a single new picture a pre-planned set of pictures are exposed from a circular orbit above the patient. By using 3D Fourier transform techniques we are able to synthesize a new X-ray picture from this set of pictures that is identical in projection to the previous one. The method has certain limits. Those are as follows: *The X-ray focus position must always be at a fixed distance from the image plane. *The object may only be translated parallel to the image plane and rotated around axes perpendicular to this plane. Under those restrictions, we may treat divergent projection pictures as if they are generated by a parallel projection of a scaled object. The unknown rotation and translation of the object in the previous case are both retrieved in two different procedures and compensated for. Experiments on synthetic data has proved that the method is working even in the presence of severe noise

Climate Change Mitigation in a Sustainable World - Findings of the IPCC 4th Assessment Report

International Nuclear Information System (INIS)

Sims, R. E. H.

2007-01-01

The 4th Assessment Report on climate change of the Intergovernmental Panel on Climate Change (IPCC, 2007) has recently been completed. The fi rst report in the IPCC 4th Assessment series by Working Group I outlined the latest knowledge on Climate Science. The second by Working Group 2 covered the possibilities for Adaptation of ecosystems, glaciers preceding, sea level rising, droughts etc in various regions. This paper is based on the findings of Working Group III as presented in the recently published report Climate Change 2007: Mitigation of Climate Change. The 27 paragraph Summary for Policy Makers was approved sentence by sentence over 4 days in May 2007 by 120 government delegations in Bangkok, Thailand. The three short Summaries for Policy Makers (SPM), Synthesis report, and the three full reports can be found at www.ipcc.ch. In addition the short Synthesis Report across all three working groups is soon to be released. The report on Mitigation attempted to compile the latest scientific knowledge relating to low-carbon emitting technologies; assessed their costs and potentials for greenhouse gas (GHG) emission avoidance; evaluated their long term prospects out to 2100 for stabilising atmospheric GHGs; provided a detailed list of policy options; and discussed the opportunities for sustainable development and equity linked with GHG abatement. Over the 3 year writing and review process, the author of this paper was the co-ordinating lead author of the writing team for the Working Group III chapter on Energy Supply. Of the 13 chapters, this one received the greatest attention with over 5000 review comments that were each responded to, and with the sections on nuclear and renewable energy receiving a major share of them. Since the 3rd Assessment Report (TAR) was published in 2001, the over-arching message now being delivered by Working Group III is a stronger but positive one: Action is required. The situation is urgent - but not beyond repair. Many energy

National climate assessment technical report on the impacts of climate and land use and land cover change

Science.gov (United States)

Thomas Loveland; Rezaul Mahmood; Toral Patel-Weynand; Krista Karstensen; Kari Beckendorf; Norman Bliss; Andrew Carleton

2012-01-01

This technical report responds to the recognition by the U.S. Global Change Research Program (USGCRP) and the National Climate Assessment (NCA) of the importance of understanding how land use and land cover (LULC) affects weather and climate variability and change and how that variability and change affects LULC. Current published, peer-reviewed, scientific literature...

Anaesthetic management for caesarean section in a case of previously operated with residual pituitary tumour

Directory of Open Access Journals (Sweden)

Prerana N Shah

2011-01-01

Full Text Available Successful anaesthetic management for caesarean section in a case with previous pituitary tumour resection, with residual tumour, is reported. The pituitary gland undergoes global hyperplasia during pregnancy. Functional pituitary tumours may exhibit symptomatic enlargement during pregnancy. Growth hormone secreting tumour is associated with acromegaly which has associated anaesthetic implications of difficult airway, systemic hypertension, and diabetes and electrolyte imbalance. Intracranial space occupying lesions can increase intra cranial pressure and compromise cerebral perfusion or cause herniation. We report management of this case.

Photometric changes on Saturn's Titan: Evidence for active cryovolcanism

Science.gov (United States)

Nelson, R.M.; Kamp, L.W.; Lopes, R.M.C.; Matson, D.L.; Kirk, R.L.; Hapke, B.W.; Wall, S.D.; Boryta, M.D.; Leader, F.E.; Smythe, W.D.; Mitchell, K.L.; Baines, K.H.; Jaumann, R.; Sotin, Christophe; Clark, R.N.; Cruikshank, D.P.; Drossart, P.; Lunine, J.I.; Combes, M.; Bellucci, G.; Bibring, J.-P.; Capaccioni, F.; Cerroni, P.; Coradini, A.; Formisano, V.; Filacchione, G.; Langevin, Y.; McCord, T.B.; Mennella, V.; Nicholson, P.D.; Sicardy, B.; Irwin, P.G.J.; Pearl, J.C.

2009-01-01

We report infrared spectrophotometric variability on the surface of Saturn's moon Titan detected in images returned by the Visual and Infrared Mapping Spectrometer (VIMS) onboard the Cassini Saturn Orbiter. The changes were observed at 7??S, 138??W and occurred between October 27, 2005 and January 15, 2006. After that date the surface was unchanged until the most recent observation, March 18, 2006. We previously reported spectrophotometric variability at another location (26??S, 78??W). Cassini Synthetic Aperture RADAR (SAR) images find that the surface morphology at both locations is consistent with surface flows possibly resulting from cryovolcanic activity (Wall et al., companion paper, this issue). The VIMS-reported time variability and SAR morphology results suggest that Titan currently exhibits intermittent surface changes consistent with present ongoing surface processes. We suggest that these processes involve material from Titan's interior being extruded or effiised and deposited on the surface, as might be expected from cryovolcanism. ?? 2009.

Gastrointestinal tolerability with ibandronate after previous weekly bisphosphonate treatment

Directory of Open Access Journals (Sweden)

Richard Derman

2009-09-01

Full Text Available Richard Derman1, Joseph D Kohles2, Ann Babbitt31Department of Obstetrics and Gynecology, Christiana Hospital, Newark, DE, USA; 2Roche, Nutley, NJ, USA; 3Greater Portland Bone and Joint Specialists, Portland, ME, USAAbstract: Data from two open-label trials (PRIOR and CURRENT of women with postmenopausal osteoporosis or osteopenia were evaluated to assess whether monthly oral and quarterly intravenous (IV ibandronate dosing improved self-reported gastrointestinal (GI tolerability for patients who had previously experienced GI irritation with bisphosphonate (BP use. In PRIOR, women who had discontinued daily or weekly BP treatment due to GI intolerance received monthly oral or quarterly IV ibandronate for 12 months. The CURRENT subanalysis included women receiving weekly BP treatment who switched to monthly oral ibandronate for six months. GI symptom severity and frequency were assessed using the Osteoporosis Patient Satisfaction Questionnaire™. In PRIOR, mean GI tolerability scores increased significantly at month 1 from screening for both treatment groups (oral: 79.3 versus 54.1; IV: 84.4 versus 51.0; p < 0.001 for both. Most patients reported improvement in GI symptom severity and frequency from baseline at all post-screening assessments (>90% at Month 10. In the CURRENT subanalysis >60% of patients reported improvements in heartburn or acid reflux and >70% indicated improvement in other stomach upset at month 6. Postmenopausal women with GI irritability with daily or weekly BPs experienced improvement in symptoms with extended dosing monthly or quarterly ibandronate compared with baseline.Keywords: ibandronate, osteoporosis, bisphosphonate, gastrointestinal

Leiomyosarcoma of the Prostate: Case Report and Review of 54 Previously Published Cases

Directory of Open Access Journals (Sweden)

Gerasimos P. Vandoros

2008-01-01

Full Text Available Prostate leiomyosarcoma is an extremely rare and highly aggressive neoplasm that accounts for less than 0.1% of primary prostate malignancies. We present a patient with primary leiomyosarcoma of the prostate and review 54 cases reported in the literature to discuss the clinical, diagnostic and therapeutic aspects of this uncommon tumor. Median survival was estimated at 17 months (95% C.I. 20.7–43.7 months and the 1-, 3-, and 5-year actuarial survival rates were 68%, 34%, and 26%, respectively. The only factors predictive of long-term survival were negative surgical margins and absence of metastatic disease at presentation. A multidisciplinary approach is necessary for appropriate management of this dire entity.

Adolescents' physical activity is associated with previous and current physical activity practice by their parents.

Science.gov (United States)

Christofaro, Diego Giulliano Destro; Andersen, Lars Bo; Andrade, Selma Maffei de; Barros, Mauro Virgílio Gomes de; Saraiva, Bruna Thamyres Ciccotti; Fernandes, Rômulo Araújo; Ritti-Dias, Raphael Mendes

The purpose of this study was to determine whether parents' current and previous physical activity practice is associated with adolescents' physical activity. The sample was composed of 1231 adolescents (14-17 years), and 1202 mothers and 871 fathers were interviewed. Weight and height of the adolescents were measured. Self-reported parents' weight and height were obtained. The current and previous physical activity levels (Baecke's questionnaire) of parents (during childhood and adolescence) and adolescents' physical activity levels were obtained using a questionnaire. The magnitude of the associations between parent and adolescent physical activity levels was determined by binary logistic regression (adjusted by sex, age, and socioeconomic level of adolescents and education level of parents). The current physical activity practice by parents was associated with adolescents' physical activity (p<0.001). The physical activities reported by parents in their childhood and adolescence were also associated with higher physical activity levels among adolescents. Adolescents whose parents were both physically active in the past and present were six times (OR=6.67 [CI=1.94-22.79]) more likely to be physically active compared to adolescents with no parents who were physically active in the past. The current and previous physical activities of parents were associated with higher levels of physical activity in adolescents, even after controlling for confounding factors. Copyright © 2017 Sociedade Brasileira de Pediatria. Published by Elsevier Editora Ltda. All rights reserved.

Adolescents' physical activity is associated with previous and current physical activity practice by their parents

Directory of Open Access Journals (Sweden)

Diego Giulliano Destro Christofaro

Full Text Available Abstract Objective: The purpose of this study was to determine whether parents' current and previous physical activity practice is associated with adolescents' physical activity. Methods: The sample was composed of 1231 adolescents (14-17 years, and 1202 mothers and 871 fathers were interviewed. Weight and height of the adolescents were measured. Self-reported parents' weight and height were obtained. The current and previous physical activity levels (Baecke's questionnaire of parents (during childhood and adolescence and adolescents' physical activity levels were obtained using a questionnaire. The magnitude of the associations between parent and adolescent physical activity levels was determined by binary logistic regression (adjusted by sex, age, and socioeconomic level of adolescents and education level of parents. Results: The current physical activity practice by parents was associated with adolescents' physical activity (p < 0.001. The physical activities reported by parents in their childhood and adolescence were also associated with higher physical activity levels among adolescents. Adolescents whose parents were both physically active in the past and present were six times (OR = 6.67 [CI = 1.94-22.79] more likely to be physically active compared to adolescents with no parents who were physically active in the past. Conclusions: The current and previous physical activities of parents were associated with higher levels of physical activity in adolescents, even after controlling for confounding factors.

Implementation of intensity ratio change and line-of-sight rate change algorithms for imaging infrared trackers

Science.gov (United States)

Viau, C. R.

2012-06-01

The use of the intensity change and line-of-sight (LOS) change concepts have previously been documented in the open-literature as techniques used by non-imaging infrared (IR) seekers to reject expendable IR countermeasures (IRCM). The purpose of this project was to implement IR counter-countermeasure (IRCCM) algorithms based on target intensity and kinematic behavior for a generic imaging IR (IIR) seeker model with the underlying goal of obtaining a better understanding of how expendable IRCM can be used to defeat the latest generation of seekers. The report describes the Intensity Ratio Change (IRC) and LOS Rate Change (LRC) discrimination techniques. The algorithms and the seeker model are implemented in a physics-based simulation product called Tactical Engagement Simulation Software (TESS™). TESS is developed in the MATLAB®/Simulink® environment and is a suite of RF/IR missile software simulators used to evaluate and analyze the effectiveness of countermeasures against various classes of guided threats. The investigation evaluates the algorithm and tests their robustness by presenting the results of batch simulation runs of surface-to-air (SAM) and air-to-air (AAM) IIR missiles engaging a non-maneuvering target platform equipped with expendable IRCM as self-protection. The report discusses how varying critical parameters such track memory time, ratio thresholds and hold time can influence the outcome of an engagement.

Sunburn and sun-protective behaviors among adults with and without previous nonmelanoma skin cancer: a population-based study

Science.gov (United States)

Fischer, Alexander H.; Wang, Timothy S.; Yenokyan, Gayane; Kang, Sewon; Chien, Anna L.

2016-01-01

Background Individuals with previous nonmelanoma skin cancer (NMSC) are at increased risk for subsequent skin cancer, and should therefore limit UV exposure. Objective To determine whether individuals with previous NMSC engage in better sun protection than those with no skin cancer history. Methods We pooled self-reported data (2005 and 2010 National Health Interview Surveys) from US non-Hispanic white adults (758 with and 34,161 without previous NMSC). We calculated adjusted prevalence odds ratios (aPOR) and 95% confidence intervals (95% CI), taking into account the complex survey design. Results Individuals with previous NMSC versus no history of NMSC had higher rates of frequent use of shade (44.3% versus 27.0%; aPOR=1.41; 1.16–1.71), long sleeves (20.5% versus 7.7%; aPOR=1.55; 1.21–1.98), a wide-brimmed hat (26.1% versus 10.5%; aPOR=1.52; 1.24–1.87), and sunscreen (53.7% versus 33.1%; aPOR=2.11; 95% CI=1.73–2.59), but did not have significantly lower odds of recent sunburn (29.7% versus 40.7%; aPOR=0.95; 0.77–1.17). Among subjects with previous NMSC, recent sunburn was inversely associated with age, sun avoidance, and shade but not sunscreen. Limitations Self-reported cross-sectional data and unavailable information quantifying regular sun exposure. Conclusion Physicians should emphasize sunburn prevention when counseling patients with previous NMSC, especially younger adults, focusing on shade and sun avoidance over sunscreen. PMID:27198078

What's in a name? Commonalities and differences in public understanding of "climate change" and "global warming"

OpenAIRE

Whitmarsh, Lorraine E.

2009-01-01

This paper reports on findings from a survey of public understanding of climate change and global warming amongst residents in the south of England. Whereas much previous research has relied on survey checklists to measure public understanding of climate change, this study employed a more qualitative approach to reveal participants' unprompted conceptions of climate change and global warming. Overall, the findings show a tendency for the public to dissociate themselves from the causes, impact...

Towards A Minimum Conceptualisation Of Ethical Organisational Change: The Platform Provided By The "King II" Report

Directory of Open Access Journals (Sweden)

C. L. Van Tonder

2006-11-01

Full Text Available Despite the fact that organisational change is one of the most frequently recurring organisational phenomena of our time, organisations do not succeed at instituting change processes effectively and dismal change "success rates" are recorded. Van Tonder and Van Vuuren (2004 suggested that the adoption of an ethical framework would significantly mitigate the implicit risk of change practices and reduce the negative consequences of such change initiatives. The literature on ethical change practices however is exceedingly sparse and offers little guidance to management on how to conduct change practices ethically. This study argues that the King II report on corporate governance indirectly yet substantially informs issues of governance, risk and ethics in change management and provides a useful point of departure for establishing ethical change practices.

Possible pulmonary Rhizopus oryzae infection in a previously healthy child after a near-drowning incident.

Science.gov (United States)

Gerlach, Magdalena M; Lippmann, Norman; Kobelt, Louise; Petzold-Quinque, Stefanie; Ritter, Lutz; Kiess, Wieland; Siekmeyer, Manuela

2016-06-01

This article reports on a previously healthy 17-month-old boy who developed pulmonary mucormycosis after a near-drowning incident in a goose pond. The patient survived without neurological sequelae and recovered, under treatment with amphotericin B, from the rare and often invasive fungal infection with Rhizopus spp., usually occurring in immunodeficient patients.

Change of risk information disclosure in annual report. Before and after earthquake disaster

International Nuclear Information System (INIS)

Ueno, Takefumi

2011-01-01

This research examines how risk information disclosure is changing in annual report before and after East Japan Great Earthquake Disaster. Company voluntary disclose risk information in annual report. Manager can decide a style and items of risk information. This paper explores risk information disclosures of Tokyo Electric Power Company, Chubu Power Electric Company, Kansai Electric Power Company and Toyota Motor Corporation. The managers except Tokyo Electric Company are likely to disclose own catastrophe risk before the disaster. However, they do not try to reduce their risk. Corporations' risk information do not link with own risk management. (author)

Rhabdomyosarcoma Arising in a Previously Irradiated Field: An Analysis of 43 Patients

Energy Technology Data Exchange (ETDEWEB)

Dang, Nguyen D. [Department of Radiation Oncology, Baylor College of Medicine, Houston, Texas (United States); Teh, Bin S. [Department of Radiation Oncology, The Methodist Hospital and Methodist Hospital Research Institute, Houston, Texas (United States); Paulino, Arnold C., E-mail: apaulino@tmhs.org [Department of Radiation Oncology, The Methodist Hospital and Methodist Hospital Research Institute, Houston, Texas (United States)

2013-03-01

Patients with soft tissue sarcomas that arise from previously irradiated fields have traditionally been reported to have a poor prognosis. In this report, we examined the characteristics and outcomes of patients who developed a rhabdomyosarcoma in a previously irradiated field (RMS-RIF); we hypothesize that these patients should have a better outcome compared to other postradiation soft tissue sarcomas as these tumors are chemosensitive and radiosensitive. A PubMed search of the literature from 1961-2010 yielded 33 studies with data for patients with RMS-RIF. The study included 43 patients with a median age of 6.5 years at the time of radiation therapy (RT) for the initial tumor. The median RT dose was 48 Gy. The median latency period, the time from RT to development of RMS-RIF, was 8 years. The 3-year overall survival for RMS-RIF was 42%. The 3-year overall survival was 66% for patients receiving chemotherapy and local treatment (surgery and/or RT) compared to 29% for those who had systemic treatment only or local treatment only (P=.049). Other factors associated with increased 3-year overall survival included retinoblastoma initial diagnosis (P<.001), age ≤18 years at diagnosis of RMS-RIF (P=.003), favorable site (P=.008), and stage 1 disease (P=.002). Age at time of RMS-RIF, retinoblastoma initial tumor, favorable site, stage 1 disease, and use of both systemic and local treatment were found to be favorable prognostic factors for 3-year overall survival.

Exercise induced ST elevation and residual myocardial ischemia in previous myocardial infarction

International Nuclear Information System (INIS)

Shimonagata, Tsuyoshi; Nishimura, Tsunehiko; Uehara, Toshiisa; Hayashida, Kohei; Saito, Muneyasu; Sumiyoshi, Tetsuya

1987-01-01

The purpose of this study was to evaluate the clinical significance of stress induced ST elevation on infarcted area in 65 patients with previous myocardial infarction (single vessel disease) who had stress thallium scan. Stress induced ST changes on infarcted area were compared with quantitative assessment of myocardial ischemia (thallium ischemic score; TIS) and extent of myocardial infarction (defect score; DS) derived from circumferential profile analysis. In patients with previous myocardial infarction in less than 3 month from the onset (n = 36), left ventricular ejection fraction (LVEF) and extent of abnormal LV wall motion were not significantly different between patients with stress induced ST elevation ( ≥ 2 mm, n = 26) and those with stress induced ST elevation ( < 2 mm, n = 10), while, in patients with previous myocardial infarction in more than 3 month (n = 29), patients with stress induced ST elevation ( ≥ 2 mm, n = 15) showed left ventricular dyskinesis more frequently than those with ST elevation ( < 2 mm, n = 14). In addition, the former showed significantly higher DS and significantly lower TIS than the latter. In patients with previous myocardial infarction in less than 3 month, patients with ST elevation ( ≥ 2 mm, n = 15) with prominent upright T wave (n = 15) had transient thallium defect in infarcted area in 73 % and they had significantly higher LVEF and TIS than those with ST elevation ( < 2 mm, n = 11). These results indicated that ST elevation in infarcted area reflect different significance according to the recovery of injured myocardium and stress induced ST elevation with prominent upright T wave in infarcted area reflect residual myocardial ischemia in less than 3 month from the onset of myocardial infarction. (author)

The Effects of the Previous Outcome on Probabilistic Choice in Rats

Science.gov (United States)

Marshall, Andrew T.; Kirkpatrick, Kimberly

2014-01-01

This study examined the effects of previous outcomes on subsequent choices in a probabilistic-choice task. Twenty-four rats were trained to choose between a certain outcome (1 or 3 pellets) versus an uncertain outcome (3 or 9 pellets), delivered with a probability of .1, .33, .67, and .9 in different phases. Uncertain outcome choices increased with the probability of uncertain food. Additionally, uncertain choices increased with the probability of uncertain food following both certain-choice outcomes and unrewarded uncertain choices. However, following uncertain-choice food outcomes, there was a tendency to choose the uncertain outcome in all cases, indicating that the rats continued to “gamble” after successful uncertain choices, regardless of the overall probability or magnitude of food. A subsequent manipulation, in which the probability of uncertain food varied within each session as a function of the previous uncertain outcome, examined how the previous outcome and probability of uncertain food affected choice in a dynamic environment. Uncertain-choice behavior increased with the probability of uncertain food. The rats exhibited increased sensitivity to probability changes and a greater degree of win–stay/lose–shift behavior than in the static phase. Simulations of two sequential choice models were performed to explore the possible mechanisms of reward value computations. The simulation results supported an exponentially decaying value function that updated as a function of trial (rather than time). These results emphasize the importance of analyzing global and local factors in choice behavior and suggest avenues for the future development of sequential-choice models. PMID:23205915

Changes in Consumer Demand Following Public Reporting of Summary Quality Ratings: An Evaluation in Nursing Homes.

Science.gov (United States)

Werner, Rachel M; Konetzka, R Tamara; Polsky, Daniel

2016-06-01

Limited consumer use of health care report cards may be due to the large amount of information presented in report cards, which can be difficult to understand. These limitations may be overcome with summary measures. Our objective was to evaluate consumer response to summary measures in the setting of nursing homes. 2005-2010 nursing home Minimum Data Set and Online Survey, Certification and Reporting (OSCAR) datasets. In December 2008, Medicare converted its nursing home report card to summary or star ratings. We test whether there was a change in consumer demand for nursing homes related to the nursing home's star rating after the information was released. The star rating system was associated with a significant change in consumer demand for low- and high-scoring facilities. After the star-based rating system was released, 1-star facilities typically lost 8 percent of their market share and 5-star facilities gained over 6 percent of their market share. The nursing home star rating system significantly affected consumer demand for high- and low-rated nursing homes. These results support the use of summary measures in report cards. © Health Research and Educational Trust.

The UK Government response to the Royal Commission on Environmental Pollution's twenty-second report: energy - the changing climate

Energy Technology Data Exchange (ETDEWEB)

NONE

2003-02-01

The Royal Commission on Environmental Pollution's Twenty Second Report 'Energy - the Changing Climate' was presented to Parliament in June 2000. The report advocates a transformation in the use of energy in the UK to counter climate change. As a contribution to global efforts to prevent excessive climate change, the Royal Commission recommends that the UK should plan to reduce carbon dioxide emissions by some 60% from current levels by about 2050. The Report explores what this will mean for industry and households and highlights how Government policies need to change. This document provides the Government's formal response to the Twenty Second Report. The response summarises the action being taken and proposed, and it relates to the Royal Commission's recommendations. Its structure is thematic, rather than being a point-by-point response. This allows the action to be described coherently, but maintains the link with the recommendations.

The frequency of previously undetectable deletions involving 3' Exons of the PMS2 gene.

Science.gov (United States)

Vaughn, Cecily P; Baker, Christine L; Samowitz, Wade S; Swensen, Jeffrey J

2013-01-01

Lynch syndrome is characterized by mutations in one of four mismatch repair genes, MLH1, MSH2, MSH6, or PMS2. Clinical mutation analysis of these genes includes sequencing of exonic regions and deletion/duplication analysis. However, detection of deletions and duplications in PMS2 has previously been confined to Exons 1-11 due to gene conversion between PMS2 and the pseudogene PMS2CL in the remaining 3' exons (Exons 12-15). We have recently described an MLPA-based method that permits detection of deletions of PMS2 Exons 12-15; however, the frequency of such deletions has not yet been determined. To address this question, we tested for 3' deletions in 58 samples that were reported to be negative for PMS2 mutations using previously available methods. All samples were from individuals whose tumors exhibited loss of PMS2 immunohistochemical staining without concomitant loss of MLH1 immunostaining. We identified seven samples in this cohort with deletions in the 3' region of PMS2, including three previously reported samples with deletions of Exons 13-15 (two samples) and Exons 14-15. Also detected were deletions of Exons 12-15, Exon 13, and Exon 14 (two samples). Breakpoint analysis of the intragenic deletions suggests they occurred through Alu-mediated recombination. Our results indicate that ∼12% of samples suspected of harboring a PMS2 mutation based on immunohistochemical staining, for which mutations have not yet been identified, would benefit from testing using the new methodology. Copyright © 2012 Wiley Periodicals, Inc.

Kernicterus with abnormal high-signal changes bilaterally in the globus pallidus: A case report.

LENUS (Irish Health Repository)

Culleton, S

2018-04-01

Kernicterus is a relatively rare consequence of hyperbilirubinemia. There is an important role for MRI imaging for this entity in the appropriate clinical context as there are distinct signal changes in the globus pallidus. A case report and image findings are presented

Is change bad? Personality change is associated with poorer psychological health and greater metabolic syndrome in midlife

Science.gov (United States)

Human, Lauren J.; Biesanz, Jeremy C.; Miller, Gregory E.; Chen, Edith; Lachman, Margie E.; Seeman, Teresa E.

2013-01-01

Objective Personality change is emerging as an important predictor of health and well-being. Extending previous research, we examined whether two types of personality change, directional and absolute, are associated with both subjective and objective indicators of health. Method Utilizing the longitudinal Midlife in the United States Survey (MIDUS) data, we examined whether both types of change over 10 years were associated with psychological well-being, self-reported global health, and the presence of metabolic syndrome (MetS) components and diagnosis. Results Socially undesirable personality change (e.g., becoming less conscientious and more neurotic) and absolute personality change were independently associated with worse perceived health and well-being at Time 2. Notably, absolute personality change, regardless of the direction, was also associated with having a greater number of MetS components and a greater probability of diagnosis at Time 2. Conclusions In sum, too much personality change may be bad for one’s health: socially undesirable and absolute personality change were both associated with worse psychological health and worse metabolic profiles over 10 years. These findings suggest that personality change may contribute to psychological and physical health, and provide initial insight into potential intermediate links between personality change and distal outcomes such as mortality. PMID:22924900

Is change bad? Personality change is associated with poorer psychological health and greater metabolic syndrome in midlife.

Science.gov (United States)

Human, Lauren J; Biesanz, Jeremy C; Miller, Gregory E; Chen, Edith; Lachman, Margie E; Seeman, Teresa E

2013-06-01

Personality change is emerging as an important predictor of health and well-being. Extending previous research, we examined whether two types of personality change, directional and absolute, are associated with both subjective and objective indicators of health. Utilizing the longitudinal Midlife in the United States survey (MIDUS) data, we examined whether both types of change over 10 years were associated with psychological well-being, self-reported global health, and the presence of metabolic syndrome (MetS) components and diagnosis. Socially undesirable personality change (e.g., becoming less conscientious and more neurotic) and absolute personality change were independently associated with worse perceived health and well-being at Time 2. Notably, absolute personality change, regardless of the direction, was also associated with having a greater number of MetS components and a greater probability of diagnosis at Time 2. In sum, too much personality change may be bad for one's health: Socially undesirable and absolute personality change were both associated with worse psychological health and worse metabolic profiles over 10 years. These findings suggest that personality change may contribute to psychological and physical health, and provide initial insight into potential intermediate links between personality change and distal outcomes such as mortality. © 2012 Wiley Periodicals, Inc.

Incidence of cancer in adolescent idiopathic scoliosis patients treated 25 years previously

DEFF Research Database (Denmark)

Simony, Ane; Hansen, Emil Jesper; Christensen, Steen Bach

2016-01-01

, is comparable to modern equipment. This is to our knowledge the first study to report increased rates of endometrial cancers in a cohort of AIS patients, and future attention is needed to reduce the radiation dose distributed to the AIS patients both pre-operatively and during surgery.......PURPOSE: To report the incidence of cancer in a cohort of adolescent idiopathic scoliosis (AIS) patients treated 25 years previously. METHODS: 215 consecutive AIS patients treated between 1983 and 1990 were identified and requested to return for clinical and radiographic examination. The incidence....... RESULTS: From the original cohort of 215 consecutive AIS patients, radiation information was available in 211 of the patients, and medical charts were available in 209 AIS patients. 170 (83 %) of the 205 AIS patients participated in the follow-up study with questionnaires. The calculated mean total...

Gonad development in Midas cichlids and the evolution of sex change in fishes.

Science.gov (United States)

Oldfield, Ronald G

2011-01-01

Some fishes mature and function as one sex and later transform to the other sex in response to social interactions. Previous evidence suggested that a change in developmental timing may be involved in the evolution of adult sex change in fishes. The most recent support for this idea came from reports that sex in the Midas cichlid, Amphilophus citrinellus, was determined by social conditions experienced at the juvenile stage. Differentiation as a male was reported to be dependent on large body size relative to group-mates, and thought to be mediated through aggressive interactions. Here I demonstrate that socially controlled sex determination does not occur as was originally reported. Previously, I found that sex was not associated with body size in juveniles either in nature or in captivity. Similarly, I found no association between aggressive behavior and sex in juveniles. I later demonstrated that socially controlled sex determination does not typically occur in the Midas cichlid and closely related species and supported an alternative mechanism to explain large body size in adult males. Finally, in the current study I analyze gonad histology of fish from the same population used by the original authors and lay to rest the idea of socially controlled sex determination in this species. Recent observations of socially controlled sex determination in juveniles of species that typically change sex at the adult stage are examples of phenotypic plasticity, not genetic variation. Therefore, juvenile socially controlled sex determination does not support a theory that a change in developmental timing is involved in the evolution of adult sex change in fishes. © 2011 Wiley Periodicals, Inc.

Correlated charge-changing uion-atom collisions. Final Technical Report

International Nuclear Information System (INIS)

John Tanis

2005-01-01

This document comprises the final technical report for atomic collisions research supported by DOE grant No. DE-FG02-87ER13778 from September 1, 2001 through August 31, 2004. The research involved the experimental investigation of excitation and charge-changing processes occurring in ion-atom and ion-molecule collisions. Major emphases of the study were: (1) interference effects resulting from coherent electron emission in H2, (2) production of doubly vacant K-shell (hollow ion) states due to electron correlation, and (3) formation of long-lived metastable states in electron transfer processes. During the period of the grant, this research resulted in 23 publications, 12 invited presentations, and 39 contributed presentations at national and international meetings and other institutions. Brief summaries of the completed research are presented below

National Diet and Nutrition Survey: fat and fatty acid intakes from the first year of the rolling programme and comparison with previous surveys

Science.gov (United States)

Pot, Gerda K.; Prynne, Celia J.; Roberts, Caireen; Olson, Ashley; Nicholson, Sonja K.; Whitton, Clare; Teucher, Birgit; Bates, Beverley; Henderson, Helen; Pigott, Sarah; Swan, Gillian; Stephen, Alison M.

2012-01-01

High saturated fat intake is an established risk factor for several chronic diseases. The objective of the present study is to report dietary intakes and main food sources of fat and fatty acids (FA) from the first year of the National Diet and Nutrition Survey (NDNS) rolling programme in the UK. Dietary data were collected using 4d estimated food diaries (n896) and compared with dietary reference values (DRV) and previous NDNS results. Total fat provided 34–36% food energy (FE) across all age groups, which was similar to previous surveys for adults. Men (19–64 years) and older girls (11–18 years) had mean intakes just above the DRV, while all other groups had mean total fat intakes of <35% FE. SFA intakes were lower compared with previous surveys, ranging from 13 to 15% FE, but still above the DRV. Mean MUFA intakes were 12.5% FE for adults and children aged 4–18 years and all were below the DRV. Mean n–3 PUFA intake represented 0.7–1.1% FE. Compared with previous survey data, the direction of change for n–3 PUFA was upwards for all age groups, although the differences in absolute terms were very small. Trans-FA intakes were lower than in previous NDNS and were less than 2g/d for all age groups, representing 0.8% FE and lower than the DRV in all age groups. In conclusion, dietary intake of fat and FA is moving towards recommended levels for the UK population. However, there remains room for considerable further improvement. PMID:21767448

Some fibrocystic breast change may be caused by sexually transmitted H. pylori during oral nipple contact: supporting literature and case report of resolution after gut H. pylori eradication treatment.

Science.gov (United States)

Kast, R E

2007-01-01

To briefly review previously published evidence for Helicobacter pylori (Hp), colonization of extra-intestinal sites and suggest an hypothesis that breast acini and ducts be added to this list, concluding such breast colonization is not rare and is a sexually transmitted infection. PubMed literature search and review with a case report. (1) Evidence indicates oral Hp is common and can remain in the mouth after successful eradication in stomach and duodenum. (2) Evidence indicates that the breast is also occasionally colonized by Hp. (3) Hp may be injected retrograde up into ducts of the breast during oral nipple stimulation during sexual activity and this Hp may give rise to some cases of fibrocystic breast change. (4) A case of painful fibrocystic change that had been present for two years in a 27 year old female, resolved after gastrointestinal Hp treatment.

Atomoxetine-Related Change in Sluggish Cognitive Tempo Is Partially Independent of Change in Attention-Deficit/Hyperactivity Disorder Inattentive Symptoms.

Science.gov (United States)

McBurnett, Keith; Clemow, David; Williams, David; Villodas, Miguel; Wietecha, Linda; Barkley, Russell

2017-02-01

To evaluate effects of atomoxetine versus placebo on sluggish cognitive tempo (SCT) and determine factors affecting improvement of SCT in children with attention-deficit/hyperactivity disorder (ADHD) with dyslexia (ADHD+D) or dyslexia only. This is a post hoc analysis of a 16-week placebo-controlled, double-blind randomized phase of a previously reported atomoxetine study in children aged 10-16 years with ADHD+D, Dyslexia-only, or ADHD-only (no placebo arm). Least squares mean changes from baseline to endpoint for atomoxetine versus placebo on the Kiddie-Sluggish Cognitive Tempo Interview (K-SCT) (Parent, Teacher, and Youth) were analyzed using analysis of covariance and multiple regression (partial R 2 ) analyses to test contributions of ADHD and dyslexia to improvements in K-SCT scores. Results were examined for the three informants within the three diagnostic groups (nine outcomes). Atomoxetine treatment was associated with significant reductions from baseline in seven of the nine outcomes using the p = 0.05 significance level, appropriate for exploratory analysis. When change in ADHD symptom severity was controlled, all of the seven SCT outcomes remained significant; changes in effect sizes were minimal. Regression analyses using SCT change as the criterion found a significant contribution by inattention change only for parent report, whereas, baseline SCT severity was a significant predictor in the randomized groups with the exception of teacher report in the Dyslexia-only group. Given that controlling for change in ADHD symptoms had little effect on change in SCT scores, findings suggest that change in SCT is substantially independent of change in ADHD. By inference, SCT and its response to treatment is a partially distinct phenomenon from ADHD response. Regression analyses did not reveal global effects of inattention change on SCT change; instead, baseline SCT severity was the strongest predictor of placebo-controlled treatment effect on SCT. Atomoxetine

Impact of previously disadvantaged land-users on sustainable ...

African Journals Online (AJOL)

Impact of previously disadvantaged land-users on sustainable agricultural ... about previously disadvantaged land users involved in communal farming systems ... of input, capital, marketing, information and land use planning, with effect on ...

Data from studies of previous radioactive waste disposal in Massachusetts Bay

International Nuclear Information System (INIS)

Curtis, W.R.; Mardis, H.M.

1984-12-01

This report presents the results of studies conducted in Massachusetts Bay during 1981 and 1982. Included are data from: (1) a side scan sonar survey of disposal areas in the Bay that was carried out by the National Oceanic and Atmospheric Administration (NOAA) for EPA; (2) Collections of sediment and biota by NOAA for radiochemical analysis by EPA; (3) collections of marketplace seafood samples by the Food and Drug Administration (FDA) for radioanalysis by both FDA and EPA; and (4) a radiological monitoring survey of LLW disposal areas by EPA to determine whether there should be any concern for public health resulting from previous LLW disposals in the Bay

AbobotulinumtoxinA Efficacy and Safety in Children With Equinus Foot Previously Treated With Botulinum Toxin.

Science.gov (United States)

Dabrowski, Edward; Bonikowski, Marcin; Gormley, Mark; Volteau, Magali; Picaut, Philippe; Delgado, Mauricio R

2018-05-01

The effects of botulinum toxin are transient, and repeat injections are required in children with lower-limb spasticity. However, the efficacy of botulinum toxin in patients who have received previous injections has remained largely unexplored. We present subgroup analyses of a phase III study conducted in ambulatory children (aged two to 17) with spastic equinus foot. Patients were randomized to single doses of abobotulinumtoxinA 10 U/kg/leg, 15 U/kg/leg, or placebo injected into the gastrocnemius-soleus complex (one or both legs). The first analysis was prespecified to review the effect of abobotulinumtoxinA in children previously treated with botulinum toxin versus those children new to the treatment; a second post hoc analysis evaluated the effect of abobotulinumtoxinA in children who changed botulinum toxin formulation. Of the 241 randomized patients, 113 had previously received botulinum toxin, including 86 who had been treated with another formulation. In both analyses, muscle tone (Modified Ashworth Scale) and the Physicians Global Assessment, at week 4, improved with abobotulinumtoxinA treatment versus placebo, regardless of baseline botulinum toxin status. Placebo responses in patients new to treatment were consistently higher than in the previously treated group. These results demonstrate similar abobotulinumtoxinA efficacy and safety profiles in children with spasticity who are new to botulinum toxin treatment and those children who were previously treated. The efficacy and safety of abobotulinumtoxinA treatment in these previously treated patients were comparable with the overall trial population, indicating that doses of 10 and 15 U/kg/leg are suitable starting doses for children with spasticity regardless of the previous botulinum toxin preparation used. Copyright © 2018 Elsevier Inc. All rights reserved.

Validation of the Online version of the Previous Day Food Questionnaire for schoolchildren

Directory of Open Access Journals (Sweden)

Raquel ENGEL

Full Text Available ABSTRACT Objective To evaluate the validity of the web-based version of the Previous Day Food Questionnaire Online for schoolchildren from the 2nd to 5th grades of elementary school. Methods Participants were 312 schoolchildren aged 7 to 12 years of a public school from the city of Florianópolis, Santa Catarina, Brazil. Validity was assessed by sensitivity, specificity, as well as by agreement rates (match, omission, and intrusion rates of food items reported by children on the Previous Day Food Questionnaire Online, using direct observation of foods/beverages eaten during school meals (mid-morning snack or afternoon snack on the previous day as the reference. Multivariate multinomial logistic regression analysis was used to evaluate the influence of participants’ characteristics on omission and intrusion rates. Results The results showed adequate sensitivity (67.7% and specificity (95.2%. There were low omission and intrusion rates of 22.8% and 29.5%, respectively when all food items were analyzed. Pizza/hamburger showed the highest omission rate, whereas milk and milk products showed the highest intrusion rate. The participants who attended school in the afternoon shift presented a higher probability of intrusion compared to their peers who attended school in the morning. Conclusion The Previous Day Food Questionnaire Online possessed satisfactory validity for the assessment of food intake at the group level in schoolchildren from the 2nd to 5th grades of public school.

Relationship between self-reported weight change, educational status, and health-related quality of life in patients with diabetes in Luxembourg.

Science.gov (United States)

Tchicaya, Anastase; Lorentz, Nathalie; Demarest, Stefaan; Beissel, Jean; Wagner, Daniel R

2015-09-18

The aim of this study was to assess the relationship between self-reported weight change, socio-economic status, and health-related quality of life (HRQOL) in patients with diabetes, 5 years after they underwent coronary angiography. Between 2013 and 2014, 1873 of 4391 patients (319 with diabetes) who underwent coronary angiography between 2008 and 2009 participated in a follow-up study. Three out of four domains of the World Health Organization Quality of Life (WHOQOL)-BREF (physical health, psychological health and social relationships) were surveyed during the follow-up period. To assess the relationship between weight change and HRQOL, generalized linear models were constructed for every dimension of the WHOQOL-BREF, with educational level as a predictor and sex, age, marital status, smoking status, hypertension, cholesterol, ischemic heart disease, acute myocardial infarction, and stable angina pectoris as covariates. The mean age of the patients was 70 years and almost three-quarters of the patients (72.7 %) were men. During the 12 months preceding the follow-up survey, 22.6 % of the patients reported weight loss, 20 % reported weight gain, and 57.4 % reported no weight change. There were significant differences in the HRQOL scores between patients who reported weight loss and those who reported either weight gain or unchanged weight. The most affected domains were physical and psychological health, with higher scores for patients who reported weight loss (54.7 and 67.2, respectively) than those who reported weight gain (46.3 and 58.5, respectively). The generalized linear model confirmed higher HRQOL scores among patients who reported weight loss and revealed an association between the HRQOL score and education level. Weight change and education level were associated with HRQOL in patients with diabetes. Self-reported weight loss and no weight change were positively associated with HRQOL in patients with diabetes, while weight gain was negatively

Spontaneous Fundal Uterine Rupture in a Pregnant Woman at 32 Weeks Gestation who had Two Previous Cesarean Sections

Directory of Open Access Journals (Sweden)

Metin Kaba

2017-08-01

Full Text Available Spontaneous uterine rupture during pregnancy can cause severe complications, even maternal and fetal demise. We report successful management of a spontaneous fundal uterine rupture in a 32 week pregnant who had undergone two previous cesarean sections due to preterm delivery. We explain causes of spontaneous uterine rupture and the management of this rare event in the presented case report.

Survival of dental implants placed in sites of previously failed implants.

Science.gov (United States)

Chrcanovic, Bruno R; Kisch, Jenö; Albrektsson, Tomas; Wennerberg, Ann

2017-11-01

To assess the survival of dental implants placed in sites of previously failed implants and to explore the possible factors that might affect the outcome of this reimplantation procedure. Patients that had failed dental implants, which were replaced with the same implant type at the same site, were included. Descriptive statistics were used to describe the patients and implants; survival analysis was also performed. The effect of systemic, environmental, and local factors on the survival of the reoperated implants was evaluated. 175 of 10,096 implants in 98 patients were replaced by another implant at the same location (159, 14, and 2 implants at second, third, and fourth surgeries, respectively). Newly replaced implants were generally of similar diameter but of shorter length compared to the previously placed fixtures. A statistically significant greater percentage of lost implants were placed in sites with low bone quantity. There was a statistically significant difference (P = 0.032) in the survival rates between implants that were inserted for the first time (94%) and implants that replaced the ones lost (73%). There was a statistically higher failure rate of the reoperated implants for patients taking antidepressants and antithrombotic agents. Dental implants replacing failed implants had lower survival rates than the rates reported for the previous attempts of implant placement. It is suggested that a site-specific negative effect may possibly be associated with this phenomenon, as well as the intake of antidepressants and antithrombotic agents. © 2016 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Denmark's national inventory report. Submitted under the United Nations framework convention on climate change, 1990-2001. Emission inventories

International Nuclear Information System (INIS)

Illerup, J.B.; Lyck, E.; Nielsen, M.; Winther, M.; Hjort Mikkelsen, M.

2003-01-01

This report is Denmark's National Inventory Report reported to the Conference of the Parties under the United Nations Framework Convention on Climate Change (UNFCCC) due bye 15 April 2003. The report contains information on Denmark's inventories for all years' from 1990 to 2001 for CO 2 , CH 4 , N 2 O, CO, NMVOC, SO 2 , HFCs, PFCs and SF 6 . (au)

Intra-Campaign Changes in Voting Preferences: The Impact of Media and Party Communication

Science.gov (United States)

Johann, David; Königslöw, Katharina Kleinen-von; Kritzinger, Sylvia; Thomas, Kathrin

2018-01-01

An increasing number of citizens change and adapt their party preferences during the electoral campaign. We analyze which short-term factors explain intra-campaign changes in voting preferences, focusing on the visibility and tone of news media reporting and party canvassing. Our analyses rely on an integrative data approach, linking data from media content analysis to public opinion data. This enables us to investigate the relative impact of news media reporting as well as party communication. Inherently, we overcome previously identified methodological problems in the study of communication effects on voting behavior. Our findings reveal that campaigns matter: Especially interpersonal party canvassing increases voters’ likelihood to change their voting preferences in favor of the respective party, whereas media effects are limited to quality news outlets and depend on individual voters’ party ambivalence.

Intra-Campaign Changes in Voting Preferences: The Impact of Media and Party Communication.

Science.gov (United States)

Johann, David; Königslöw, Katharina Kleinen-von; Kritzinger, Sylvia; Thomas, Kathrin

2018-01-01

An increasing number of citizens change and adapt their party preferences during the electoral campaign. We analyze which short-term factors explain intra-campaign changes in voting preferences, focusing on the visibility and tone of news media reporting and party canvassing. Our analyses rely on an integrative data approach, linking data from media content analysis to public opinion data. This enables us to investigate the relative impact of news media reporting as well as party communication. Inherently, we overcome previously identified methodological problems in the study of communication effects on voting behavior. Our findings reveal that campaigns matter: Especially interpersonal party canvassing increases voters' likelihood to change their voting preferences in favor of the respective party, whereas media effects are limited to quality news outlets and depend on individual voters' party ambivalence.

Tunisia: World Oil Report 1991

International Nuclear Information System (INIS)

Anon.

1991-01-01

This paper reports on more attractive E and P terms, and the Abiod Chalk oil play which means busier exploration in Tunisia. E and P agreement terms and conditions have been liberalized in the face of declining oil and gas production, thus encouraging development of smaller, previously marginal prospects. Ownership and acreage changes may have significant impact in the next few years as Texaco, under a farm-in, has acquired 60% and operatorship of Conquest Exploration's El Jem onshore block and Samedan acquired large acreage interests from Royal Dutch Shell

Deepwater Gulf of Mexico more profitable than previously thought

International Nuclear Information System (INIS)

Craig, M.J.K.; Hyde, S.T.

1997-01-01

Economic evaluations and recent experience show that the deepwater Gulf of Mexico (GOM) is much more profitable than previously thought. Four factors contributing to the changed viewpoint are: First, deepwater reservoirs have proved to have excellent productive capacity, distribution, and continuity when compared to correlative-age shelf deltaic sands. Second, improved technologies and lower perceived risks have lowered the cost of floating production systems (FPSs). Third, projects now get on-line quicker. Fourth, a collection of other important factors are: Reduced geologic risk and associated high success rates for deepwater GOM wells due primarily to improved seismic imaging and processing tools (3D, AVO, etc.); absence of any political risk in the deepwater GOM (common overseas, and very significant in some international areas); and positive impact of deepwater federal royalty relief. This article uses hypothetical reserve distributions and price forecasts to illustrate indicative economics of deepwater prospects. Economics of Shell Oil Co.'s three deepwater projects are also discussed

Endurance training-induced changes in the GH-IGF-I axis influence maximal muscle strength in previously untrained men.

Science.gov (United States)

Grandys, Marcin; Majerczak, Joanna; Kuczek, Piotr; Sztefko, Krystyna; Duda, Krzysztof; Zoladz, Jerzy A

2017-02-01

In this study we have determined the effects of 20weeks of endurance running training on the GH-IGF-I axis changes in the context of the skeletal muscle performance and physical capacity level. Before and after the endurance training program a maximal incremental exercise tests, a 1500m race and a muscle strength measurements were performed and the blood samples were taken to determine both resting as well as end-exercise serum growth hormone (GH), insulin-like growth hormone-I (IGF-I), insulin-like growth hormone binding protein-3 (IGFBP-3) and plasma interleukin-6 (IL-6) concentrations. 20weeks of endurance running training improved power output generated at the end of the maximal incremental test by 24% (P<0.012), 1500m running time by 13% (P<0.012) and maximal muscle strength by 9% (P<0.02). End-exercise IGF-I/IGFBP-3 ratio was decreased by 22% after the training (P<0.04) and the magnitude of IGF-I/IGFBP-3 ratio decrease (ΔIGF-I/IGFBP-3 ex ) was 2.3 times higher after the training (P<0.04). The magnitude of the exercise-induced changes in IGFBP-3 concentration was also significantly higher (P<0.04) and there was a trend toward lower end-exercise IGF-I concentration (P=0.08) after the training. These changes were accompanied by a significantly higher (30%) end-exercise IL-6 concentration (P<0.01) as well as by a 3.4 times higher magnitude of IL-6 increase (P<0.02) after the training. Moreover, there were strong positive correlations between changes in resting serum IGF-I concentration (ΔIGF-I res ) and IGF-I/IGFBP-3 ratio (ΔIGF-I/IGFBP-3 res ) and changes in muscle strength (ΔMVC) (r=0.95, P=0.0003 and r=0.90, P=0.002, respectively). The training-induced changes in the components of the GH-IGF-I axis may have additive effects on skeletal muscle performance and physical capacity improvement. Copyright © 2016 Elsevier Ltd. All rights reserved.

78 FR 28118 - Vidalia Onions Grown in Georgia; Change in Reporting and Assessment Requirements

Science.gov (United States)

2013-05-14

... onion producers in the designated production area. Small agricultural service firms, which include...; FV13-955-1 IR] Vidalia Onions Grown in Georgia; Change in Reporting and Assessment Requirements AGENCY... Vidalia onions grown in Georgia (order). The order regulates the handling of Vidalia onions grown in...

Human factors engineering report for the cold vacuum drying facility

Energy Technology Data Exchange (ETDEWEB)

IMKER, F.W.

1999-06-30

The purpose of this report is to present the results and findings of the final Human Factors Engineering (HFE) technical analysis and evaluation of the Cold Vacuum Drying Facility (CVDF). Ergonomics issues are also addressed in this report, as appropriate. This report follows up and completes the preliminary work accomplished and reported by the Preliminary HFE Analysis report (SNF-2825, Spent Nuclear Fuel Project Cold Vacuum Drying Facility Human Factors Engineering Analysis: Results and Findings). This analysis avoids redundancy of effort except for ensuring that previously recommended HFE design changes have not affected other parts of the system. Changes in one part of the system may affect other parts of the system where those changes were not applied. The final HFE analysis and evaluation of the CVDF human-machine interactions (HMI) was expanded to include: the physical work environment, human-computer interface (HCI) including workstation and software, operator tasks, tools, maintainability, communications, staffing, training, and the overall ability of humans to accomplish their responsibilities, as appropriate. Key focal areas for this report are the process bay operations, process water conditioning (PWC) skid, tank room, and Central Control Room operations. These key areas contain the system safety-class components and are the foundation for the human factors design basis of the CVDF.

Human factors engineering report for the cold vacuum drying facility

International Nuclear Information System (INIS)

IMKER, F.W.

1999-01-01

The purpose of this report is to present the results and findings of the final Human Factors Engineering (HFE) technical analysis and evaluation of the Cold Vacuum Drying Facility (CVDF). Ergonomics issues are also addressed in this report, as appropriate. This report follows up and completes the preliminary work accomplished and reported by the Preliminary HFE Analysis report (SNF-2825, Spent Nuclear Fuel Project Cold Vacuum Drying Facility Human Factors Engineering Analysis: Results and Findings). This analysis avoids redundancy of effort except for ensuring that previously recommended HFE design changes have not affected other parts of the system. Changes in one part of the system may affect other parts of the system where those changes were not applied. The final HFE analysis and evaluation of the CVDF human-machine interactions (HMI) was expanded to include: the physical work environment, human-computer interface (HCI) including workstation and software, operator tasks, tools, maintainability, communications, staffing, training, and the overall ability of humans to accomplish their responsibilities, as appropriate. Key focal areas for this report are the process bay operations, process water conditioning (PWC) skid, tank room, and Central Control Room operations. These key areas contain the system safety-class components and are the foundation for the human factors design basis of the CVDF

Bird Species and Climate Change. The Global Status Report. A synthesis of current scientific understanding of anthropogenic climate change impacts on global bird species now, and projected future effects

International Nuclear Information System (INIS)

Wormworth, J.; Mallon, K.

2006-01-01

The results of a global analysis of current and future impacts of climate change on birds are presented. The report reviews more than 200 research reports to assemble a clear and consistent picture of climatic risk to this important animal group, illustrated with numerous examples and case studies. It is found that: climate change now affects bird species' behaviour, ranges and population dynamics; some bird species are already experiencing strong negative impacts from climate change; and in future, subject to greenhouse gas emissions levels and climatic response, climate change will put large numbers of bird species at risk of extinction, with estimates of extinction rates varying from 2 to 72%, depending on the region, climate scenario and potential for birds to shift to new habitat

Bird Species and Climate Change. The Global Status Report. A synthesis of current scientific understanding of anthropogenic climate change impacts on global bird species now, and projected future effects

Energy Technology Data Exchange (ETDEWEB)

Wormworth, J.; Mallon, K. [Climate Risk Pty Limited, Fairlight (Australia)

2006-07-01

The results of a global analysis of current and future impacts of climate change on birds are presented. The report reviews more than 200 research reports to assemble a clear and consistent picture of climatic risk to this important animal group, illustrated with numerous examples and case studies. It is found that: climate change now affects bird species' behaviour, ranges and population dynamics; some bird species are already experiencing strong negative impacts from climate change; and in future, subject to greenhouse gas emissions levels and climatic response, climate change will put large numbers of bird species at risk of extinction, with estimates of extinction rates varying from 2 to 72%, depending on the region, climate scenario and potential for birds to shift to new habitat.

Adenomyoepithelioma of the breast with hemorrhagic change diagnosed as papiloma on core needle biopsy: A case report

Energy Technology Data Exchange (ETDEWEB)

Nam, Kyung Sun; Kim, Ji Young; Kim, Soung Hee; Bae, Kyung Eun; Lee, Ji Hae; Kang, Mi Jin; Jeong, Myeong Ja; Kim, Soo Hyun; Kim, Jae Hyung [Dept. of Radiology, Sanggye Paik Hospital, Inje University College of Medicine, Seoul (Korea, Republic of)

2016-11-15

Adenomyoepithelioma (AME) is a rare disease entity that represents biphasic proliferation of ductal epithelial and myoepithelial cells. AME can be confused with other neoplasms including malignancy because AME has various cytologic characteristics and nonspecific radiologic features. We describe an unusual AME with hemorrhagic change that was diagnosed as papilloma on core needle biopsy three times previously. The imaging features of AME are also discussed here.

Preconception lifestyle changes in women with planned pregnancies.

Science.gov (United States)

Goossens, Joline; Beeckman, Dimitri; Van Hecke, Ann; Delbaere, Ilse; Verhaeghe, Sofie

2018-01-01

(1) to study preconception lifestyle changes and associated factors in women with planned pregnancies; (2) to assess the prevalence of risk factors for adverse pregnancy outcomes in women not reporting any preconception lifestyle changes; and (3) to explore the need for and use of preconception-related advice. secondary data analysis of a cross-sectional study about pregnancy planning. six Flemish Hospitals (Belgium). four hundred and thirty women with a planned pregnancy ending in birth. preconception lifestyle changes were measured during the first 5 days postpartum using the validated London Measure of Unplanned Pregnancy. The following changes were assessed: folic acid or multivitamin intake, smoking reduction or cessation, alcohol reduction or cessation, caffeine reduction or cessation, eating more healthily, achieving a healthier weight, obtaining medical or health advice, or another self-reported preconception lifestyle change. most women (83%) that planned their pregnancy reported ≥1 lifestyle change in preparation for pregnancy. Overall, nulliparous women (OR 2.18, 95% CI 1.23-3.87) and women with a previous miscarriage (OR 2.44, 95% CI 1.14-5.21) were more likely to prepare for pregnancy, while experiencing financial difficulties (OR 0.20, 95% CI 0.04-0.97) or having a lower educational level (OR 0.56, 95% CI 0.32-0.99) decreased the likelihood of preparing for pregnancy. Half of the women (48%) obtained advice about preconception health, and 86% of these women received their advice from a professional caregiver. Three-quarters (77%) of the women who did not improve their lifestyle before conceiving reported one or more risk factors for adverse pregnancy outcomes. multiparous women and women of lower socio-economic status were less likely to change their lifestyle before conception. Strategies to promote preconception health in these women need to be tailored to their needs and characteristics to overcome barriers to change. It may be advantageous to

Prospective Primary Teachers' Understanding of Climate Change, Greenhouse Effect, and Ozone Layer Depletion

Science.gov (United States)

Papadimitriou, Vasiliki

2004-01-01

Climate change is one of the most serious global environmental problems and for that reason there has been lately a great interest in educating pupils, the future citizens, about it. Previous research has shown that pupils of all ages and teachers hold many misconceptions and misunderstandings concerning this issue. This paper reports on research…

Report to New England Governors and Eastern Canadian Premiers on climate change projects

International Nuclear Information System (INIS)

2002-08-01

The Premiers-Governors energy discussions are aimed at promoting joint energy cooperation between provinces and states. This report outlines the major accomplishments in the implementation of the Climate Change Action Plan adopted by the Conference in 1998. The project priorities for the coming year are also outlined. In 2001, the New England Governors (NEG) and the Eastern Canadian Premiers (ECP) directed the Environment Committee and the Northeast International Committee on Energy (NICE) to implement a plan to develop a regional emissions inventory so that participating jurisdictions would have common data for measuring progress. The plan also identified specific climate actions that could be readily implemented. This report describes the results of 5 working groups which were created to focus on the following potential categories: energy, transportation, inventory and registry, adaptation, and 'lead by example'. In addition to the working groups, the Climate Change Steering Committee developed 4 proposals for consideration for implementation. These were the LED Traffic Light Proposal, the College and University Partnerships in Emissions Reductions, State/Provincial Purchasing Programs for High Efficiency-Low Emission Office Equipment, and Use of Cleaner, More Energy-Efficient Vehicles in State/Provincial Fleets. The Steering Committee will also pursue other tasks in the coming year, including the study of other proposals for cost-effective measures that could contribute to the goals of the Climate Change Action Plan, examine Internet options for coordinating internal project work, examine opportunities to pursue climate action, and identify opportunities to improve vehicle fuel efficiency

Polychlorinated biphenyl exposure, diabetes and endogenous hormones: a cross-sectional study in men previously employed at a capacitor manufacturing plant.

Science.gov (United States)

Persky, Victoria; Piorkowski, Julie; Turyk, Mary; Freels, Sally; Chatterton, Robert; Dimos, John; Bradlow, H Leon; Chary, Lin Kaatz; Burse, Virlyn; Unterman, Terry; Sepkovic, Daniel W; McCann, Kenneth

2012-08-29

Studies have shown associations of diabetes and endogenous hormones with exposure to a wide variety of organochlorines. We have previously reported positive associations of polychlorinated biphenyls (PCBs) and inverse associations of selected steroid hormones with diabetes in postmenopausal women previously employed in a capacitor manufacturing plant. This paper examines associations of PCBs with diabetes and endogenous hormones in 63 men previously employed at the same plant who in 1996 underwent surveys of their exposure and medical history and collection of bloods and urine for measurements of PCBs, lipids, liver function, hematologic markers and endogenous hormones. PCB exposure was positively associated with diabetes and age and inversely associated with thyroid stimulating hormone and triiodothyronine-uptake. History of diabetes was significantly related to total PCBs and all PCB functional groupings, but not to quarters worked and job score, after control for potential confounders. None of the exposures were related to insulin resistance (HOMA-IR) in non-diabetic men. Associations of PCBs with specific endogenous hormones differ in some respects from previous findings in postmenopausal women employed at the capacitor plant. Results from this study, however, do confirm previous reports relating PCB exposure to diabetes and suggest that these associations are not mediated by measured endogenous hormones.

HIV risk perception and testing behaviours among men having sex with men (MSM) reporting potential transmission risks in the previous 12 months from a large online sample of MSM living in Germany.

Science.gov (United States)

Marcus, Ulrich; Gassowski, Martyna; Drewes, Jochen

2016-10-22

HIV testing and serostatus awareness are essential to implement biomedical strategies (treatment as prevention; oral chemoprophylaxis), and for effective serostatus-based behaviours (HIV serosorting; strategic positioning). The analysis focuses on the associations between reported sexual risks, the perceived risk for HIV infection, and HIV testing behaviour in order to identify the most relevant barriers for HIV test uptake among MSM living in Germany. MSM were recruited to a nationwide anonymous online-survey in 2013 on MSM social networking/dating sites. Questions covered testing behaviours, reasons for testing decisions, and HIV risk perception (5-point scale). Additional questions addressed arguments in favour of home/ home collection testing (HT). Using descriptive statistics and logistic regression we compared men reporting recent HIV testing (RT; previous 12 month) with men never tested (NT) in a subsample not previously diagnosed with HIV and reporting ≥2 episodes of condomless anal intercourse (CLAI) with a non-steady partner of unknown HIV serostatus in the previous 12 months. The subsample consisted of 775 RT (13 % of RT) and 396 NT (7 % of NT). The number of CLAI episodes in the last 12 months with non-steady partners of unknown HIV status did not differ significantly between the groups, but RT reported significantly higher numbers of partners (>5 AI partners: 65 vs. 44 %). While perceived risks regarding last AI were comparable between the groups, 49vs. 30 % NT were risks (67 %) and routine testing (49 %) were the most common testing reasons for RT, while the strong belief not to be infected (59 %) and various worries (41 %) and fears of testing positive (35 %) were predominant reasons of NT. Greater anonymity (aOR 3.2; 2.4-4.4), less embarrassment, (aOR 2.8; 1.9-4.1), and avoiding discussions on sexual behaviour (aOR 1.6; 1.1-2.2) were emphasized in favour of HT by NT. Perceived partner knowledge and reasons reflecting perceived gay- and

Characterization of Cladosporols from the Marine Algal-Derived Endophytic Fungus Cladosporium cladosporioides EN-399 and Configurational Revision of the Previously Reported Cladosporol Derivatives.

Science.gov (United States)

Li, Hong-Lei; Li, Xiao-Ming; Mándi, Attila; Antus, Sándor; Li, Xin; Zhang, Peng; Liu, Yang; Kurtán, Tibor; Wang, Bin-Gui

2017-10-06

Four new cladosporol derivatives, cladosporols F-I (1-4), the known cladosporol C (5), and its new epimer, cladosporol J (6), were isolated and identified from the marine algal-derived endophytic fungus Cladosporium cladosporioides EN-399. Their structures were determined by detailed interpretation of NMR and MS data, and the absolute configurations were established on the basis of TDDFT-ECD and OR calculations. The configurational assignment of cladosporols F (1) and G (2) showed that the previously reported absolute configuration of cladosporol A and all the related cladosporols need to be revised from (4'R) to (4'S). Compounds 1-6 showed antibacterial activity against Escherichia coli, Micrococcus luteus, and Vibrio harveyi with MIC values ranging from 4 to 128 μg/mL. Compound 3 showed significant cytotoxicity against A549, Huh7, and LM3 cell lines with IC 50 values of 5.0, 1.0, and 4.1 μM, respectively, and compound 5 showed activity against H446 cell line with IC 50 value of 4.0 μM.

Erlotinib-induced rash spares previously irradiated skin

International Nuclear Information System (INIS)

Lips, Irene M.; Vonk, Ernest J.A.; Koster, Mariska E.Y.; Houwing, Ronald H.

2011-01-01

Erlotinib is an epidermal growth factor receptor inhibitor prescribed to patients with locally advanced or metastasized non-small cell lung carcinoma after failure of at least one earlier chemotherapy treatment. Approximately 75% of the patients treated with erlotinib develop acneiform skin rashes. A patient treated with erlotinib 3 months after finishing concomitant treatment with chemotherapy and radiotherapy for non-small cell lung cancer is presented. Unexpectedly, the part of the skin that had been included in his previously radiotherapy field was completely spared from the erlotinib-induced acneiform skin rash. The exact mechanism of erlotinib-induced rash sparing in previously irradiated skin is unclear. The underlying mechanism of this phenomenon needs to be explored further, because the number of patients being treated with a combination of both therapeutic modalities is increasing. The therapeutic effect of erlotinib in the area of the previously irradiated lesion should be assessed. (orig.)

Residual limb fluid volume change and volume accommodation: Relationships to activity and self-report outcomes in people with trans-tibial amputation.

Science.gov (United States)

Sanders, Joan E; Youngblood, Robert T; Hafner, Brian J; Ciol, Marcia A; Allyn, Katheryn J; Gardner, David; Cagle, John C; Redd, Christian B; Dietrich, Colin R

2018-02-01

Fluctuations in limb volume degrade prosthesis fit and require users to accommodate changes using management strategies, such as donning and doffing prosthetic socks. To examine how activities and self-report outcomes relate to daily changes in residual limb fluid volume and volume accommodation. Standardized, two-part laboratory protocol with an interim observational period. Participants were classified as "accommodators" or "non-accommodators," based on self-report prosthetic sock use. Participants' residual limb fluid volume change was measured using a custom bioimpedance analyzer and a standardized in-laboratory activity protocol. Self-report health outcomes were assessed with the Socket Comfort Score and Prosthesis Evaluation Questionnaire. Activity was monitored while participants left the laboratory for at least 3 h. They then returned to repeat the bioimpedance test protocol. Twenty-nine people were enrolled. Morning-to-afternoon percent limb fluid volume change per hour was not strongly correlated to percent time weight-bearing or to self-report outcomes. As a group, non-accommodators ( n = 15) spent more time with their prosthesis doffed and reported better outcomes than accommodators. Factors other than time weight-bearing may contribute to morning-to-afternoon limb fluid volume changes and reported satisfaction with the prosthesis among trans-tibial prosthesis users. Temporary doffing may be a more effective and satisfying accommodation method than sock addition. Clinical relevance Practitioners should be mindful that daily limb fluid volume change and prosthesis satisfaction are not dictated exclusively by activity. Temporarily doffing the prosthesis may slow daily limb fluid volume loss and should be investigated as an alternative strategy to sock addition.

Detecting changes in real-world objects: The relationship between visual long-term memory and change blindness.

Science.gov (United States)

Brady, Timothy F; Konkle, Talia; Oliva, Aude; Alvarez, George A

2009-01-01

A large body of literature has shown that observers often fail to notice significant changes in visual scenes, even when these changes happen right in front of their eyes. For instance, people often fail to notice if their conversation partner is switched to another person, or if large background objects suddenly disappear.1,2 These 'change blindness' studies have led to the inference that the amount of information we remember about each item in a visual scene may be quite low.1 However, in recent work we have demonstrated that long-term memory is capable of storing a massive number of visual objects with significant detail about each item.3 In the present paper we attempt to reconcile these findings by demonstrating that observers do not experience 'change blindness' with the real world objects used in our previous experiment if they are given sufficient time to encode each item. The results reported here suggest that one of the major causes of change blindness for real-world objects is a lack of encoding time or attention to each object (see also refs. 4 and 5).

Time course of changes in cerebral blood flow velocity after tourniquet deflation in patients with diabetes mellitus or previous stroke under sevoflurane anesthesia.

Science.gov (United States)

Hinohara, Hiroshi; Kadoi, Yuji; Takahashi, Kenichiro; Saito, Shigeru; Kawauchi, Chikara; Mizutani, Akio

2011-06-01

We observed an increase in mean middle cerebral artery blood flow velocity (V(mca)) after tourniquet deflation during orthopedic surgery under sevoflurane anesthesia in patients with diabetes mellitus or previous stroke. Eight controls, seven insulin-treated diabetic patients, and eight previous stroke patients were studied. Arterial blood pressure, heart rate, V(mca), arterial blood gases, and plasma lactate levels were measured every minute for 10 min after tourniquet release in all patients. V(mca) was measured using a transcranial Doppler probe. V(mca) in all three groups increased after tourniquet deflation, the increase lasting for 4 or 5 min. However, the degree of increase in V(mca) in the diabetic patients was smaller than that in the other two groups after tourniquet deflation (at 2 min after tourniquet deflation: control 58.5 ± 3.3, previous stroke 58.4 ± 4.6, diabetes 51.7 ± 2.3; P < 0.05 compared with the other two groups). In conclusion, the degree of increase in V (mca) in diabetic patients is smaller than that in controls and patients with previous stroke.

76 FR 59542 - Mandatory Reporting of Greenhouse Gases: Changes to Provisions for Electronics Manufacturing To...

Science.gov (United States)

2011-09-27

... Mandatory Reporting of Greenhouse Gases: Changes to Provisions for Electronics Manufacturing To Provide... regulation to amend the calculation and monitoring provisions in the Electronics Manufacturing portion of the... Electronics Manufacturing 334111 Microcomputer manufacturing facilities. 334413 Semiconductor, photovoltaic...

Vaginal prostaglandin gel to induce labour in women with one previous caesarean section.

LENUS (Irish Health Repository)

Agnew, G

2012-02-01

This retrospective study reviewed the mode of delivery when vaginal prostaglandins were used to induce labour in women with a single previous lower segment caesarean section. Over a 4-year period, PGE 2 gel was used cautiously in low doses in 54 women. Induction with PGE 2 gel was associated with an overall vaginal birth after caesarean section (VBAC) rate of 74%, which compared favourably with the 74% VBAC rate in women who went into spontaneous labour (n = 1969). There were no adverse outcomes recorded after the prostaglandin inductions but the number reported are too small to draw any conclusions about the risks, such as uterine rupture. We report our results because they may be helpful in assessing the chances of a successful VBAC in the uncommon clinical circumstances where prostaglandin induction is being considered.

Urinary incontinence and vaginal squeeze pressure two years post-cesarean delivery in primiparous women with previous gestational diabetes mellitus

OpenAIRE

Barbosa, Angélica Mércia Pascon; Dias, Adriano; Marini, Gabriela; Calderon, Iracema Mattos Paranhos; Witkin, Steven; Rudge, Marilza Vieira Cunha

2011-01-01

OBJECTIVE: To assess the prevalence of urinary incontinence and associated vaginal squeeze pressure in primiparous women with and without previous gestational diabetes mellitus two years post-cesarean delivery. METHODS: Primiparous women who delivered by cesarean two years previously were interviewed about the delivery and the occurrence of incontinence. Incontinence was reported by the women and vaginal pressure evaluated by a Perina perineometer. Sixty-three women with gestational diabetes ...

Maternal and foetal outcome in term patients with previous one lower segment cesarean section

OpenAIRE

Meena Naresh Satia; Kimaya A. Mali; Rakhi Sikarwar

2016-01-01

Background: In modern day obstetric practice we encounter increasing number of patients with history of caesarean section because of rise in primary caesarean due to changing trends in their indications. There is increasing fear and anxiety by obstetricians for managing these cases from medico legal point of view. Present study was done to look at the feto-maternal outcome and for appropriate mode of delivery and overall to conduct the proper management of patients with previous one lower...

Delayed vaginal reconstruction in the fibrotic pelvis following radiation or previous reconstruction

International Nuclear Information System (INIS)

Berek, J.S.; Hacker, N.F.; Lagasse, L.D.; Smith, M.L.

1983-01-01

Vaginal reconstruction was performed in 14 patients who had developed vaginal stenosis secondary to extensive pelvic fibrosis after pelvic radiation therapy (12 patients) or prior vaginal reconstruction (2 patients). Sixteen procedures were performed using a split-thickness skin graft. All patients had satisfactory vaginal restoration, and 12 patients reported good vaginal function. No fistula developed as a result of the operative procedure, but one patient later developed a rectovaginal fistula resulting from tumor recurrence. Successful vaginal reconstruction can be achieved even years after initial therapy in patients who develop an obliterated vagina from previous radiation or surgery

Congenital costo-vertebral fibrous band and congenital kyphoscoliosis: a previously unreported combination.

Science.gov (United States)

Eid, Tony; Ghostine, Bachir; Kreichaty, Gaby; Daher, Paul; Ghanem, Ismat

2013-05-01

Congenital kyphoscoliosis (CKS) results from abnormal vertebral chondrification. Congenital fibrous bands occur in several locations with variable impact on vertebral development. We report a previously unreported case of a female infant with CKS presenting with an L2 hypoplastic vertebra and a costo-vertebral fibrous band extending to the skin in the form of a dimple. We also describe the therapeutic approach, consisting of surgical excision of the fibrous band and postoperative fulltime bracing, with a 7-year follow-up. We recommend a high index of suspicion in any unusual presentation of CKS and insist on case by case management in such cases.

Climate change 101 : understanding and responding to global climate change

Science.gov (United States)

2009-01-01

To inform the climate change dialogue, the Pew Center on Global Climate Change and the Pew Center on the States have developed a series of brief reports entitled Climate Change 101: Understanding and Responding to Global Climate Change. These reports...

Indiana pouch continent urinary reservoir in patients with previous pelvic irradiation

International Nuclear Information System (INIS)

Mannel, R.S.; Braly, P.S.; Buller, R.E.

1990-01-01

Little information exists on the use of continent urinary reservoirs in patients with previous pelvic irradiation. We report the use of the Indiana pouch urinary reservoir in ten women with a history of pelvic irradiation for cervical cancer, of whom eight underwent a total pelvic exenteration for recurrent pelvic tumor and two had diversion for radiation-induced vesicovaginal fistula. All ten women achieved daytime continence, with a median time between catheterizations of 4.5 hours and a median pouch capacity of 500 mL. There was no evidence of leakage from the reservoir or significant ureteral reflux or obstruction on postoperative radiographic evaluation. No patient has required reoperation or had significant postoperative complications with the technique described

Conference Report: "Health Policy and Programs Evaluative Research for Social Change". An Ibero-American Symposium

Directory of Open Access Journals (Sweden)

Francisco Mercado-Martínez

2008-05-01

Full Text Available This is a report of the "Health Policy and Programs Evaluative Research for Social Change" Ibero-American Symposium held in Guadalajara, Mexico November 1-3, 2006. Attendees represented eight countries, and were associated with NGO's and academic and health services organizations. The most important themes included in the debates were the meaning of qualitative and evaluative health research for social change, the challenges of teaching for change, ethical challenges, and possibilities for making the findings of qualitative research available to different groups or stakeholders (users, policy makers, professionals, and the population as a whole. URN: urn:nbn:de:0114-fqs0802194

Summary for Policy Makers: Intergovernmental Panel on Climate Change Special Report Renewable Energy Sources (SRREN)

Energy Technology Data Exchange (ETDEWEB)

Arvizu, Dan; Bruckner, Thomas; Christensen, John; Devernay, Jean-Michel; Faaij , Andre; Fischedick, Manfred; Goldstein, Barry; Hansen, Gerrit; Huckerby , John; Jager-Waldau, Arnulf; Kadner, Susanne; Kammen, Daniel; Krey, Volker; Kumar, Arun; Lewis , Anthony; Lucon, Oswaldo; Matschoss, Patrick; Maurice, Lourdes; Mitchell , Catherine; Moomaw, William; Moreira, Jose; Nadai, Alain; Nilsson, Lars J.; Nyboer, John; Rahman, Atiq; Sathaye, Jayant; Sawin, Janet; Schaeffer, Roberto; Schei, Tormod; Schlomer, Steffen; Sims, Ralph; von Stechow, Christoph; Verbruggen, Aviel; Urama, Kevin; Wiser, Ryan; Yamba, Francis; Zwickel, Timm

2011-05-08

The Working Group III Special Report on Renewable Energy Sources and Climate Change Mitigation (SRREN) presents an assessment of the literature on the scientific, technological, environmental, economic and social aspects of the contribution of six renewable energy (RE) sources to the mitigation of climate change. It is intended to provide policy relevant information to governments, intergovernmental processes and other interested parties. This Summary for Policymakers provides an overview of the SRREN, summarizing the essential findings. The SRREN consists of 11 chapters. Chapter 1 sets the context for RE and climate change; Chapters 2 through 7 provide information on six RE technologies, and Chapters 8 through 11 address integrative issues.

Solid Waste Integrated Forecast Technical (SWIFT) Report FY 2001 to FY 2046 Volume 1

International Nuclear Information System (INIS)

BARCOT, R.A.

2001-01-01

In an effort to maintain an up-to-date Solid Waste Forecast, Fluor Hanford, Inc. requested a midyear update to the FY2001 Solid Waste Forecast collected in June 2000. Below is a list of generators reporting significant changes from the baseline FY2001 forecast, as well as approved generators previously not reporting wastes. The updated data was collected in February 2001. The cumulative effect of the changes in the near term was minor. Included in this update are waste generation maps for onsite facilities. The maps are updated annually and use the baseline forecast as a data reference

Patient emotions and perceptions of antiepileptic drug changes and titration during treatment for epilepsy.

Science.gov (United States)

Fishman, Jesse; Cohen, Greg; Josephson, Colin; Collier, Ann Marie; Bharatham, Srikanth; Zhang, Ying; Wild, Imane

2017-04-01

To investigate the impact of antiepileptic drug (AED) change and dose titration on the emotional well-being of patients with epilepsy. Members of an online epilepsy community were invited to voluntarily participate in an online survey. The cross-sectional anonymous survey consisted of 31 multiple choice questions balanced in terms of variety and positivity/negativity of emotions concerning participants' most recent AED change. To substantiate survey results, spontaneous comments from epilepsy-related online forums and social media websites that mentioned participants' experiences with AED medication changes (termed passive listening statements) were analyzed and categorized by theme. All 345 survey participants (270 [78.3%] female; 172 [49.9%] were 26-45years old) self-reported an epilepsy/seizure diagnosis and were currently taking seizure medication; 263 (76.2%) were taking ≥2 AEDs and 301 (87.2%) had ≥1 seizure in the previous 18months. All participants reported a medication change within the previous 12months (dose increased [153 participants (44.3%)], medication added [105 (30.4%)], dose decreased [49 (14.2%)], medication removed [38 (11.0%)]). Improving seizure control (247 [71.6%]) and adverse events (109 [31.6%]) were the most common reasons for medication change. Primary emotions most associated (≥10% of participants) with an AED regimen change were (before medication change; during/after medication change) hopefulness (50 [14.5%]; 43 [12.5%]), uncertainty (50 [14.5%]; 69 [20.0%]), and anxiety (35 [10.1%]; 45 [13.0%]), and were largely due to concerns whether the change would work (212/345 [61.4%]; 180/345 [52.2%]). In the text analysis segment aimed at validating the survey, 230 participants' passive listening statements about medication titration were analyzed; additional seizure activity during dose titration (93 [40.4%]), adverse events during titration (71 [30.9%]), higher medication dosages (33 [14.3%]), and drug costs (25 [10.9%]) were the

Rib cage deformity during two-stage tissue expander breast reconstruction in patient with previous radiotherapy: a case report

Directory of Open Access Journals (Sweden)

Aleš Porčnik

2016-02-01

Full Text Available Patients undergoing two-stage breast reconstruction with tissue expander and a history of previous irradiation are predisposed to a various chest-wall deformations more than non-irradiated patients. If chest-wall depression with/without rib fracture is found intra-operatively, bigger implant should be used, with a subsequent radiologic evaluation. In the future, the development of a new, modified expander with a harder base could minimise such complications.

Molecular Imaging with Activatable Reporter Systems

Directory of Open Access Journals (Sweden)

Gang Niu, Xiaoyuan Chen

2012-01-01

Full Text Available Molecular imaging is a newly emerged multiple disciplinary field that aims to visualize, characterize and quantitatively measure biological processes at cellular and molecular levels in humans and other living systems. A reporter gene is a piece of DNA encoding reporter protein, which presents as a readily measurable phenotype that can be distinguished easily from the background of endogenous protein. After being transferred into cells of organ systems (transgenes, the reporter gene can be utilized to visualize transcriptional and posttranscriptional regulation of gene expression, protein-protein interactions, or trafficking of proteins or cells in living subjects. Herein, we review previous classification of reporter genes and regroup the reporter gene based imaging as basic, inducible and activatable, based on the regulation of reporter gene transcription and post-translational modification of reporter proteins. We then focus on activatable reporters, in which the signal can be activated at the posttranslational level for visualizing protein-protein interactions, protein phosphorylation or tertiary structure changes. The applications of several types of activatable reporters will also be summarized. We conclude that activatable reporter imaging can benefit both basic biomedical research and drug development.

Standardization for climate change. Approaches and perspectives. Final report; Normstelling voor klimaatverandering. Invalshoeken en perspectieven. Eindrapport

Energy Technology Data Exchange (ETDEWEB)

Weterings, R.

1995-01-01

The results of a project, aimed at support of the environmental quality target for climate policy on a national level (Follow-up Memorandum Climatic Change of the Dutch government) and on an international level (elaboration of the UN Framework Convention on Climate Change). In order to generate ideas for standards of the climate policy a workshop was held on Environmental Quality and Climate. During the workshop standards of climatic change were highlighted from different points of view. Those views and perspectives are analyzed and the results are presented in this report. 4 figs., 31 refs.

Do emotional intelligence and previous caring experience influence student nurse performance? A comparative analysis.

Science.gov (United States)

Stenhouse, Rosie; Snowden, Austyn; Young, Jenny; Carver, Fiona; Carver, Hannah; Brown, Norrie

2016-08-01

Reports of poor nursing care have focused attention on values based selection of candidates onto nursing programmes. Values based selection lacks clarity and valid measures. Previous caring experience might lead to better care. Emotional intelligence (EI) might be associated with performance, is conceptualised and measurable. To examine the impact of 1) previous caring experience, 2) emotional intelligence 3) social connection scores on performance and retention in a cohort of first year nursing and midwifery students in Scotland. A longitudinal, quasi experimental design. Adult and mental health nursing, and midwifery programmes in a Scottish University. Adult, mental health and midwifery students (n=598) completed the Trait Emotional Intelligence Questionnaire-short form and Schutte's Emotional Intelligence Scale on entry to their programmes at a Scottish University, alongside demographic and previous caring experience data. Social connection was calculated from a subset of questions identified within the TEIQue-SF in a prior factor and Rasch analysis. Student performance was calculated as the mean mark across the year. Withdrawal data were gathered. 598 students completed baseline measures. 315 students declared previous caring experience, 277 not. An independent-samples t-test identified that those without previous caring experience scored higher on performance (57.33±11.38) than those with previous caring experience (54.87±11.19), a statistically significant difference of 2.47 (95% CI, 0.54 to 4.38), t(533)=2.52, p=.012. Emotional intelligence scores were not associated with performance. Social connection scores for those withdrawing (mean rank=249) and those remaining (mean rank=304.75) were statistically significantly different, U=15,300, z=-2.61, p$_amp_$lt;0.009. Previous caring experience led to worse performance in this cohort. Emotional intelligence was not a useful indicator of performance. Lower scores on the social connection factor were associated

New population-based exome data question the pathogenicity of some genetic variants previously associated with Marfan syndrome

DEFF Research Database (Denmark)

Yang, Ren-Qiang; Jabbari, Javad; Cheng, Xiao-Shu

2014-01-01

BACKGROUND: Marfan syndrome (MFS) is a rare autosomal dominantly inherited connective tissue disorder with an estimated prevalence of 1:5,000. More than 1000 variants have been previously reported to be associated with MFS. However, the disease-causing effect of these variants may be questionable...

Automatic electromagnetic valve for previous vacuum

International Nuclear Information System (INIS)

Granados, C. E.; Martin, F.

1959-01-01

A valve which permits the maintenance of an installation vacuum when electric current fails is described. It also lets the air in the previous vacuum bomb to prevent the oil ascending in the vacuum tubes. (Author)

Adjusting to future demands in healthcare: Curriculum changes and nursing students' self-reported professional competence.

Science.gov (United States)

Theander, Kersti; Wilde-Larsson, Bodil; Carlsson, Marianne; Florin, Jan; Gardulf, Ann; Johansson, Eva; Lindholm, Christina; Nordström, Gun; Nilsson, Jan

2016-02-01

Nursing competence is of significant importance for patient care. Newly graduated nursing students rate their competence as high. However, the impact of different designs of nursing curricula on nursing students' self-reported nursing competence areas is seldom reported. To compare newly graduated nursing students' self-reported professional competence before and after the implementation of a new nursing curriculum. The study had a descriptive comparative design. Nursing students, who graduated in 2011, having studied according to an older curriculum, were compared with those who graduated in 2014, after a new nursing curriculum with more focus on person-centered nursing had been implemented. A higher education nursing program at a Swedish university. In total, 119 (2011 n=69, 2014 n=50) nursing students responded. Nursing students' self-reported professional competencies were assessed with the Nurse Professional Competence (NPC) scale. There were no significant differences between the two groups of nursing students, who graduated in 2011 and 2014, respectively, with regard to age, sex, education, or work experience. Both groups rated their competencies as very high. Competence in value-based nursing was perceived to be significantly higher after the change in curriculum. The lowest competence, both in 2011 and 2014, was reported in education and supervision of staff and students. Our findings indicate that newly graduated nursing students - both those following the old curriculum and the first batch of students following the new one - perceive that their professional competence is high. Competence in value-based nursing, measured with the NPC scale, was reported higher after the implementation of a new curriculum, reflecting curriculum changes with more focus on person-centered nursing. Copyright © 2015 Elsevier Ltd. All rights reserved.

77 FR 21813 - Changes to the Generic Aging Lessons Learned (GALL) Report Revision 2 AMP XI.M41, “Buried and...

Science.gov (United States)

2012-04-11

... NUCLEAR REGULATORY COMMISSION [NRC-2012-0055] Changes to the Generic Aging Lessons Learned (GALL) Report Revision 2 AMP XI.M41, ``Buried and Underground Piping and Tanks'' AGENCY: Nuclear Regulatory... Guidance (LR-ISG), LR-ISG-2011-03, ``Changes to GALL Report Revision 2 Aging Management Program (AMP) XI...

Medical homes for at-risk children: parental reports of clinician-parent relationships, anticipatory guidance, and behavior changes.

Science.gov (United States)

Nelson, Catherine S; Higman, Susan M; Sia, Calvin; McFarlane, Elizabeth; Fuddy, Loretta; Duggan, Anne K

2005-01-01

Family-centeredness, compassion, and trust are 3 attributes of the clinician-parent relationship in the medical home. Among adults, these attributes are associated with patients' adherence to clinicians' advice. The objectives were (1) to measure medical home attributes related to the clinician-parent relationship, (2) to measure provision of anticipatory guidance regarding injury and illness prevention, (3) to relate anticipatory guidance to parental behavior changes, and (4) to relate medical home attributes to anticipatory guidance and parental behavior changes. A cross-sectional study of data collected among at-risk families when children were 1 year of age, in a randomized, controlled trial of a home-visiting program to prevent child abuse and neglect, was performed. Modified subscales of the Primary Care Assessment Survey were used to measure parental ratings of clinicians' family-centeredness, compassion, and trust. Parental reports of provision of anticipatory guidance regarding injury and illness prevention topics (smoke alarms, infant walkers, car seats, hot water temperature, stair guards, sunscreen, firearm safety, and bottle propping) and behavior changes were recorded. Of the 564 mothers interviewed when their children were 1 year of age, 402 (71%) had a primary care provider and had complete data for anticipatory guidance items. By definition, poverty, partner violence, poor maternal mental health, and maternal substance abuse were common in the study sample. Maternal ratings of clinicians' family-centeredness, compassion, and trust were fairly high but ranged widely and varied among population subgroups. Families reported anticipatory guidance for a mean of 4.6 +/- 2.2 topics relevant for discussion. Each medical home attribute was positively associated with parental reports of completeness of anticipatory guidance, ie, family-centeredness (beta = .026, SE = .004), compassion (beta = .019, SE = .005), and trust (beta = .016, SE = .005). Parents

Human Development report 2007/2008 - Fighting climate change: human solidarity in a divided world

International Nuclear Information System (INIS)

2007-01-01

Climate change is the defining human development challenge of the 21. Century. Failure to respond to that challenge will stall and then reverse international efforts to reduce poverty. The poorest countries and most vulnerable citizens will suffer the earliest and most damaging setbacks, even though they have contributed least to the problem. Looking to the future, no country - however wealthy or powerful - will be immune to the impact of global warming. The Human Development Report 2007/2008 shows that climate change is not just a future scenario. Increased exposure to droughts, floods and storms is already destroying opportunity and reinforcing inequality. Meanwhile, there is now overwhelming scientific evidence that the world is moving towards the point at which irreversible ecological catastrophe becomes unavoidable. Business-as-usual climate change points in a clear direction: unprecedented reversal in human development in our lifetime, and acute risks for our children and their grandchildren. There is a window of opportunity for avoiding the most damaging climate change impacts, but that window is closing: the world has less than a decade to change course. Actions taken - or not taken - in the years ahead will have a profound bearing on the future course of human development. The world lacks neither the financial resources nor the technological capabilities to act. What is missing is a sense of urgency, human solidarity and collective interest. As the Human Development Report 2007/2008 argues, climate change poses challenges at many levels. In a divided but ecologically interdependent world, it challenges all people to reflect upon how we manage the environment of the one thing that we share in common: planet Earth. It challenges us to reflect on social justice and human rights across countries and generations. It challenges political leaders and people in rich nations to acknowledge their historic responsibility for the problem, and to initiate deep and

Propaganda, News, or Education: Reporting Changing Arctic Sea Ice Conditions

Science.gov (United States)

Leitzell, K.; Meier, W.

2010-12-01

The National Snow and Ice Data Center provides information on Arctic sea ice conditions via the Arctic Sea Ice News & Analysis (ASINA) website. As a result of this effort to explain climatic data to the general public, we have attracted a huge amount of attention from our readers. Sometimes, people write to thank us for the information and the explanation. But people also write to accuse us of bias, slant, or outright lies in our posts. The topic of climate change is a minefield full of political animosity, and even the most carefully written verbiage can appear incomplete or biased to some audiences. Our strategy has been to report the data and stick to the areas in which our scientists are experts. The ASINA team carefully edits our posts to make sure that all statements are based on the science and not on opinion. Often this means using some technical language that may be difficult for a layperson to understand. However, we provide concise definitions for technical terms where appropriate. The hope is that by communicating the data clearly, without an agenda, we can let the science speak for itself. Is this an effective strategy to communicate clearly about the changing climate? Or does it downplay the seriousness of climate change? By writing at a more advanced level and avoiding oversimplification, we require our readers to work harder. But we may also maintain the attention of skeptics, convincing them to read further and become more knowledgeable about the topic.

European Climate Change Programme. Working Group II. Impacts and Adaptation. Urban Planning and Construction. Sectoral Report

International Nuclear Information System (INIS)

2007-03-01

Adaptation is a new policy area for the European Climate Change Policy. The Impacts and Adaptation Workgroup has been set up as part of European Climate Change Programme (ECCP II). The main objective of the workgroup is to explore options to improve Europe's resilience to climate change impacts, to encourage the integration of climate change adaptation into other policy areas at the European, national, regional and local level and to define the role of EU-wide policies complementing action by Member States. The aim of this initial programme of work is to identify good practice in the development of adaptation policy and foster learning from different sectoral experiences and explore a possible EU role in adaptation policies. The Commission has led a series of 10 sectoral meetings looking at adaptation issues for different sectors. One of these meetings looked at the impacts on urban planning and infrastructure in particular. This report summarises the state of play in the urban planning sector in relation to adaptation to climate change on the basis of the information gathered at the stakeholder meeting. Some of the other stakeholder meetings, such as the meeting on human health, have a strong connection with the urban planning agenda. Therefore, some actions in the sector report on adaptation and human health relate to urban planning and infrastructure considerations

Measuring the Success of Changes to Existing Business Intelligence Solutions to Improve Business Intelligence Reporting

OpenAIRE

Dedić, Nedim; Stanier, Clare

2016-01-01

Evaluating the success of changes to an existing Business Intelligence (BI) environment means that there is a need to compare the level of user satisfaction with the original and amended versions of the application. The focus of this paper is on producing an evaluation tool, which can be used to measure the success of changes to existing BI solutions to support improved BI reporting. The paper identifies the users involved in the BI process and investigates what is meant by satisfaction in th...

Changes in self-reported driving intentions and attitudes while learning to drive in Great Britain.

Science.gov (United States)

Helman, S; Kinnear, N A D; McKenna, F P; Allsop, R E; Horswill, M S

2013-10-01

Novice drivers are overrepresented in traffic collisions, especially in their first year of solo driving. It is widely accepted that some driving behaviours (such as speeding and thrill-seeking) increase risk in this group. Increasingly research is suggesting that attitudes and behavioural intentions held in the pre-driver and learning stage are important in determining later driver behaviour in solo driving. In this study we examine changes in several self-reported attitudes and behavioural intentions across the learning stage in a sample of learner drivers in Great Britain. A sample of 204 learner drivers completed a self-report questionnaire near the beginning of their learning, and then again shortly after they passed their practical driving test. Results showed that self-reported intentions regarding speed choice, perceptions regarding skill level, and intentions regarding thrill-seeking (through driving) became less safe over this time period, while self-reported intentions regarding following distance and overtaking tendency became safer. The results are discussed with reference to models of driver behaviour that focus on task difficulty; it is suggested that the manner in which behind-the-wheel experience relates to the risk measures of interest may be the key determining factor in how these change over the course of learning to drive. Crown Copyright © 2013. Published by Elsevier Ltd. All rights reserved.

Trends in marine climate change research in the Nordic region since the first IPCC report

DEFF Research Database (Denmark)

Pedersen, Martin Wæver; Kokkalis, Alexandros; Bardarson, H.

2016-01-01

Oceans are exposed to anthropogenic climate change shifting marine systems toward potential instabilities. The physical, biological and social implications of such shifts can be assessed within individual scientific disciplines, but can only be fully understood by combining knowledge and expertise...... across disciplines. For climate change related problems these research directions have been well-established since the publication of the first IPCC report in 1990, however it is not well-documented to what extent these directions are reflected in published research. Focusing on the Nordic region, we...... evaluated the development of climate change related marine science by quantifying trends in number of publications, disciplinarity, and scientific focus of 1362 research articles published between 1990 and 2011. Our analysis showed a faster increase in publications within climate change related marine...

Tank farm restoration and safe operation, Project W-314, upgrade scope summary report (USSR)

International Nuclear Information System (INIS)

Gilbert, J.L.

1998-01-01

The revision to the Project W-314 Upgrade Scope Summary Report (USSR), incorporates changes to the project scope from customer guidance. Included are incorporation of the recommendations from HNF-2500, agreements regarding interfaces with Project W-211, and assumption of scope previously assigned to Project W-454

The Response Shift Bias in Self-Report Tests: A Function of an Expectation of Change or a Shift in Internal Scaling?

Science.gov (United States)

Riedel, Sharon; And Others

Self-report, pre/post testing is a frequently employed measure of therapeutic change. To investigate whether expectation of change might be an alternative explanation to the scale shift explanation of response shift bias in a self-report measure, a two-session assertiveness training intervention for college women was evaluated under manipulated…

Changes in the relationship between nursing home financial performance and quality of care under public reporting.

Science.gov (United States)

Park, Jeongyoung; Werner, Rachel M

2011-07-01

The relationship between financial performance and quality of care in nursing homes is not well defined and prior work has been mixed. The recent focus on improving the quality of nursing homes through market-based incentives such as public reporting may have changed this relationship, as public reporting provides nursing homes with increased incentives to engage in quality-based competition. If quality improvement activities require substantial production costs, nursing home profitability may become a more important predictor of quality under public reporting. This study explores the relationship between financial performance and quality of care and test whether this relationship changes under public reporting. Using a 10-year (fiscal years 1997-2006) panel data set of 9444 skilled nursing facilities in the US, this study employs a facility fixed-effects with and without instrumental variables approach to test the effect of finances on quality improvement and correct for potential endogeneity. The results show that better financial performance, as reflected by the 1-year lagged total profit margin, is modestly associated with higher quality but only after public reporting is initiated. These findings have important policy implications as federal and state governments use market-based incentives to increase demand for high-quality care and induce providers to compete based on quality. Copyright © 2010 John Wiley & Sons, Ltd.

Sunburn and sun-protective behaviors among adults with and without previous nonmelanoma skin cancer (NMSC): A population-based study.

Science.gov (United States)

Fischer, Alexander H; Wang, Timothy S; Yenokyan, Gayane; Kang, Sewon; Chien, Anna L

2016-08-01

Individuals with previous nonmelanoma skin cancer (NMSC) are at increased risk for subsequent skin cancer, and should therefore limit ultraviolet exposure. We sought to determine whether individuals with previous NMSC engage in better sun protection than those with no skin cancer history. We pooled self-reported data (2005 and 2010 National Health Interview Surveys) from US non-Hispanic white adults (758 with and 34,161 without previous NMSC). We calculated adjusted prevalence odds ratios (aPOR) and 95% confidence intervals (CI), taking into account the complex survey design. Individuals with previous NMSC versus no history of NMSC had higher rates of frequent use of shade (44.3% vs 27.0%; aPOR 1.41; 95% CI 1.16-1.71), long sleeves (20.5% vs 7.7%; aPOR 1.55; 95% CI 1.21-1.98), a wide-brimmed hat (26.1% vs 10.5%; aPOR 1.52; 95% CI 1.24-1.87), and sunscreen (53.7% vs 33.1%; aPOR 2.11; 95% CI 1.73-2.59), but did not have significantly lower odds of recent sunburn (29.7% vs 40.7%; aPOR 0.95; 95% CI 0.77-1.17). Among those with previous NMSC, recent sunburn was inversely associated with age, sun avoidance, and shade but not sunscreen. Self-reported cross-sectional data and unavailable information quantifying regular sun exposure are limitations. Physicians should emphasize sunburn prevention when counseling patients with previous NMSC, especially younger adults, focusing on shade and sun avoidance over sunscreen. Copyright © 2016 American Academy of Dermatology, Inc. Published by Elsevier Inc. All rights reserved.

Contribution of the working group 2 to the fourth evaluation report of the inter government expert group on the climatic change. Evaluation 2007 of the climatic changes: impacts, adaptation and vulnerability

International Nuclear Information System (INIS)

2007-01-01

This document exposes the results of the fourth evaluation report of the working group II of the inter government experts group on the climatic change. This evaluation presents the today scientific understanding of the climatic change impacts on the humans and their adaptation ability and vulnerability. It is based on the GIEC evaluations and new knowledge added since the third evaluation report. (A.L.B.)

UNSCEAR report 2006, 2008, and 2010

International Nuclear Information System (INIS)

Yonehara, Hidenori

2013-01-01

Explained is the outline of the recently issued Reports in the title by UN Scientific Committee on the Effect of Atomic Radiation (UNSCEAR). The Report 2006 (Effects of Ionizing Radiation) contains Vol. I of the report to UN and of scientific attachments of A. epidemiological studies of radiation and cancer and B. epidemiological assessment of cardiovascular and other non-cancerous diseases after radiation exposure; and Vol. II of the attachments of C. non-target effect and late effect by exposure to ionizing radiation, D. effect of ionizing radiation on immune system and E. assessment of the effect of radon-222 source in residence and in workplace. The definition of the upper limit of low dose is changed to be 100 mGy from previous 200 mGy. The Report 2008 (Sources and Effects of Ionizing Radiation) contains Vol. I of the report to UN and the attachments of A. exposure in medicare and B. exposure of the public and workers to various sources; and Vol. II of C. exposure by accidents, D. health effect by radiation from Chernobyl accident and E. effect of ionizing radiation on non-human livings. Yearly medical dose per person is increased to be 0.6 mSv from previous 0.4 mSv. The Report 2010 summarizes the low-dose radiation effects on health described in the Report 2006 concerning the radiation-induced cancer formation and genetic effects. In the latter, the threshold value 100 mSv is assumed for the fetal exposure to yield abnormality. National Institute of Radiological Sciences (NIRS) has been responsible for publishing Japanese version of UNSCEAR Reports under contract with UN. The role of UNSCEAR is conceivably re-realized important by our society in particular after Fukushima Nuclear Power Plant Accident, of which Report is in preparation for publication. (T.T.)

Alveolar nerve repositioning with rescue implants for management of previous treatment. A clinical report.

Science.gov (United States)

Amet, Edward M; Uehlein, Chris

2013-12-01

The goal of modern implant dentistry is to return patients to oral health in a rapid and predictable fashion, following a diagnostically driven treatment plan. If only a limited number of implants can be placed, or some fail and the prosthetic phase of implant dentistry is chosen to complete the patient's treatment, the final outcome may result in partial patient satisfaction and is commonly referred to as a "compromise." Previous All-on-4 implant treatment for the patient presented here resulted in a compromise, with an inadequate support system for the mandibular prosthesis and a maxillary complete denture with poor esthetics. The patient was unable to function adequately and also was disappointed with the resulting appearance. Correction of the compromised treatment consisted of bilateral inferior alveolar nerve elevation and repositioning without bone removal for lateral transposition, to gain room for rescue implants for a totally implant-supported and stabilized prosthesis. Treatment time to return the patient to satisfactory comfort, function, facial esthetics, and speech was approximately 2 weeks. The definitive mandibular prosthesis was designed for total implant support and stability with patient retrievability. Adequate space between the mandibular bar system and the soft tissue created a high water bridge effect for self-cleansing. Following a short interim mandibular healing period, the maxillary sinuses were bilaterally grafted to compensate for bone inadequacies and deficiencies for future maxillary implant reconstruction. © 2013 by the American College of Prosthodontists.

Climate change on Twitter: topics, communities and conversations about the 2013 IPCC Working Group 1 report.

Science.gov (United States)

Pearce, Warren; Holmberg, Kim; Hellsten, Iina; Nerlich, Brigitte

2014-01-01

In September 2013 the Intergovernmental Panel on Climate Change published its Working Group 1 report, the first comprehensive assessment of physical climate science in six years, constituting a critical event in the societal debate about climate change. This paper analyses the nature of this debate in one public forum: Twitter. Using statistical methods, tweets were analyzed to discover the hashtags used when people tweeted about the IPCC report, and how Twitter users formed communities around their conversational connections. In short, the paper presents the topics and tweeters at this particular moment in the climate debate. The most used hashtags related to themes of science, geographical location and social issues connected to climate change. Particularly noteworthy were tweets connected to Australian politics, US politics, geoengineering and fracking. Three communities of Twitter users were identified. Researcher coding of Twitter users showed how these varied according to geographical location and whether users were supportive, unsupportive or neutral in their tweets about the IPCC. Overall, users were most likely to converse with users holding similar views. However, qualitative analysis suggested the emergence of a community of Twitter users, predominantly based in the UK, where greater interaction between contrasting views took place. This analysis also illustrated the presence of a campaign by the non-governmental organization Avaaz, aimed at increasing media coverage of the IPCC report.

Climate change on Twitter: topics, communities and conversations about the 2013 IPCC Working Group 1 report.

Directory of Open Access Journals (Sweden)

Warren Pearce

Full Text Available In September 2013 the Intergovernmental Panel on Climate Change published its Working Group 1 report, the first comprehensive assessment of physical climate science in six years, constituting a critical event in the societal debate about climate change. This paper analyses the nature of this debate in one public forum: Twitter. Using statistical methods, tweets were analyzed to discover the hashtags used when people tweeted about the IPCC report, and how Twitter users formed communities around their conversational connections. In short, the paper presents the topics and tweeters at this particular moment in the climate debate. The most used hashtags related to themes of science, geographical location and social issues connected to climate change. Particularly noteworthy were tweets connected to Australian politics, US politics, geoengineering and fracking. Three communities of Twitter users were identified. Researcher coding of Twitter users showed how these varied according to geographical location and whether users were supportive, unsupportive or neutral in their tweets about the IPCC. Overall, users were most likely to converse with users holding similar views. However, qualitative analysis suggested the emergence of a community of Twitter users, predominantly based in the UK, where greater interaction between contrasting views took place. This analysis also illustrated the presence of a campaign by the non-governmental organization Avaaz, aimed at increasing media coverage of the IPCC report.

Denmark's national inventory report 2006 - Submitted under the United Nations framework convention on climate change, 1990-2004. Emission inventories

International Nuclear Information System (INIS)

Illerup, J.B.; Lyck, E.; Nielsen, Ole-Kenneth

2006-08-01

This report is Denmark's National Inventory Report reported to the Conference of the Parties under the United Nations Framework Convention on Climate Change (UNFCCC) due by 15 April 2006. The report contains information on Denmark's inventories for all years' from 1990 to 2004 for CO 2 , CH 4 , N 2 O, HFCs, PFCs and SF 6 , CO, NMVOC, SO 2 . (au)

Case report of right hamate hook fracture in a patient with previous fracture history of left hamate hook: is it hamate bipartite?

Directory of Open Access Journals (Sweden)

Norton Sandra

2006-10-01

Full Text Available Abstract Background Hamate hook fracture is a common fracture in golfers and others who play sports that involve rackets or sticks such as tennis or hockey. This patient had a previous hamate fracture in the opposing wrist along with potential features of hamate bipartite. Case presentation A 19 year old male presented with a complaint of right wrist pain on the ulnar side of the wrist with no apparent mechanism of injury. The pain came on gradually one week before being seen in the office and he reported no prior care for the complaint. His history includes traumatic left hamate hook fracture with surgical excision. Conclusion The patient was found to have marked tenderness over the hamate and with a prior fracture to the other wrist, computed tomography of the wrist was ordered revealing a fracture to the hamate hook in the right wrist. He was referred for surgical evaluation and the hook of the hamate was excised. Post-surgically, the patient was able to return to normal activity within eight weeks. This case is indicative of fracture rather than hamate bipartite. This fracture should be considered in a case of ulnar sided wrist pain where marked tenderness is noted over the hamate, especially after participation in club or racket sports.

Report on modelling the macroeconomic competitiveness impacts of EU climate change policy

International Nuclear Information System (INIS)

2007-01-01

This report details the results of a study carried out by Oxford Economics on the macroeconomic impacts of the EU Emissions Trading Scheme (EU ETS) on competitiveness in different sectors and different Member States. An economic model was used to assess the impacts of carbon pricing, building on previous work that looked at the effects on the UK economy. The model was used to estimate the impact on competitiveness and output associated with various carbon prices and assumptions for the proposed third EU ETS trading period (2013-2023) by sector for all countries. The model covered 30 sectors for each of the 27 EU Member states plus the USA, Japan and China. The report describes the EU model methodology (direct cost effects, second-round cost effects, cost effects without substitution, cost effects after substitution, pass through to prices, and output effects) and the key results in terms of: impacts of carbon-reduction policies unilateral EU action, sectoral impacts, electricity generation sector only; the non-power sector in the ETS; global action; developed world action; and a summary across all scenarios. The three annexes set out the UK Energy Industry Model (UKEIM), model equations for the EU-wide model and modelling assumptions for electricity generation

Total hip arthroplasty after a previous pelvic osteotomy: A systematic review and meta-analysis.

Science.gov (United States)

Shigemura, T; Yamamoto, Y; Murata, Y; Sato, T; Tsuchiya, R; Wada, Y

2018-06-01

There are several reports regarding total hip arthroplasty (THA) after a previous pelvic osteotomy (PO). However, to our knowledge, until now there has been no formal systematic review and meta-analysis published to summarize the clinical results of THA after a previous PO. Therefore, we conducted a systematic review and meta-analysis of results of THA after a previous PO. We focus on these questions as follows: does a previous PO affect the results of subsequent THA, such as clinical outcomes, operative time, operative blood loss, and radiological parameters. Using PubMed, Web of Science, and Cochrane Library, we searched for relevant original papers. The pooling of data was performed using RevMan software (version 5.3, Cochrane Collaboration, Oxford, UK). A p-value50%, significant heterogeneity was assumed and a random-effects model was applied for the meta-analysis. A fixed-effects model was applied in the absence of significant heterogeneity. Eleven studies were included in this meta-analysis. The pooled results indicated that there was no significant difference in postoperative Merle D'Aubigne-Postel score (I 2 =0%, SMD=-0.15, 95% CI: -0.36 to 0.06, p=0.17), postoperative Harris hip score (I 2 =60%, SMD=-0.23, 95% CI: -0.50 to 0.05, p=0.10), operative time (I 2 =86%, SMD=0.37, 95% CI: -0.09 to 0.82, p=0.11), operative blood loss (I 2 =82%, SMD=0.23, 95% CI: -0.17 to 0.63, p=0.25), and cup abduction angle (I 2 =43%, SMD=-0.08, 95% CI: -0.25 to 0.09, p=0.38) between THA with and without a previous PO. However, cup anteversion angle of THA with a previous PO was significantly smaller than that of without a previous PO (I 2 =77%, SMD=-0.63, 95% CI: -1.13 to -0.13, p=0.01). Systematic review and meta-analysis of results of THA after a previous PO was performed. A previous PO did not affect the results of subsequent THA, except for cup anteversion. Because of the low quality evidence currently available, high-quality randomized controlled trials are required

Changes in self-reported and parent-reported health-related quality of life in overweight children and adolescents participating in an outpatient training: findings from a 12-month follow-up study

Directory of Open Access Journals (Sweden)

Finne Emily

2013-01-01

Full Text Available Abstract Background Health-related quality of life (HRQoL was found to improve in participants of weight management interventions. However, information on moderately overweight youth as well as on maintaining HRQoL improvements following treatment is sparse. We studied the HRQoL of 74 overweight, but not obese participants (32.4% male, mean age = 11.61 ± 1.70 SD of a comprehensive and effective six-month outpatient training at four time-points up to 12 months after end of treatment. Methods HRQoL was measured by self-report and proxy-report versions of the generic German KINDL-R, including six sub domains, and an obesity-specific additional module. Changes in original and z-standardized scores were analyzed by (2×4 doubly multivariate analysis of variance. This was done separately for self- and proxy-reported HRQoL, taking into account further socio-demographic background variables and social desirability. Additionally, correlations between changes in HRQoL scores and changes in zBMI were examined. Results There were significant multivariate time effects for self-reported and proxy-reported HRQoL and a significant time-gender interaction in self-reports revealed (p 2 = 0.14-0.19. Generic HRQoL further increased after end of treatment. The largest effects were found on the dimension self-esteem (partial η2 = 0.08-0.09 for proxy- and self-reported z-scores, respectively. Correlations with changes in weight were gender-specific, and weight reduction was only associated with HRQoL improvements in girls. Conclusions Positive effects of outpatient training on generic and weight-specific HRQoL of moderately overweight (not obese children and adolescents could be demonstrated. Improvements in HRQoL were not consistently bound to weight reduction. While changes in weight-specific HRQoL were more immediate, generic HRQoL further increased after treatment ended. An extended follow-up may therefore be needed to scrutinize HRQo

Relationship Between Changes in Workplace Bullying Status and the Reporting of Personality Characteristics

DEFF Research Database (Denmark)

Persson, Roger; Høgh, Annie; Grynderup, Matias Brdsgaard

2016-01-01

Objective: To examine whether a shift in work-related bullying status, from being non-bullied to being bullied or vice versa, was associated with changes in reporting of personality characteristics. Methods: Data on bullying and personality (neuroticism, extraversion, and sense of coherence) were...... collected in three waves approximately 2 years apart (N1/44947). Using a within-subjects design, personality change scores that followed altered bullying status were evaluated with one-sample t tests. Sensitivity analyses targeted depressive symptoms. Results: Shifts from non-bullied to frequently bullied...... were associated with increased neuroticism or decreased sense of coherence manageability scores. Shifts from bullied to non-bullied were associated with decreasing neuroticism and increasing extraversion scores, or increasing sense of coherence meaningfulness and comprehensibility scores. Excluding...

Unique Bond Breaking in Crystalline Phase Change Materials and the Quest for Metavalent Bonding.

Science.gov (United States)

Zhu, Min; Cojocaru-Mirédin, Oana; Mio, Antonio M; Keutgen, Jens; Küpers, Michael; Yu, Yuan; Cho, Ju-Young; Dronskowski, Richard; Wuttig, Matthias

2018-05-01

Laser-assisted field evaporation is studied in a large number of compounds, including amorphous and crystalline phase change materials employing atom probe tomography. This study reveals significant differences in field evaporation between amorphous and crystalline phase change materials. High probabilities for multiple events with more than a single ion detected per laser pulse are only found for crystalline phase change materials. The specifics of this unusual field evaporation are unlike any other mechanism shown previously to lead to high probabilities of multiple events. On the contrary, amorphous phase change materials as well as other covalently bonded compounds and metals possess much lower probabilities for multiple events. Hence, laser-assisted field evaporation in amorphous and crystalline phase change materials reveals striking differences in bond rupture. This is indicative for pronounced differences in bonding. These findings imply that the bonding mechanism in crystalline phase change materials differs substantially from conventional bonding mechanisms such as metallic, ionic, and covalent bonding. Instead, the data reported here confirm a recently developed conjecture, namely that metavalent bonding is a novel bonding mechanism besides those mentioned previously. © 2018 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Reading Aloud: Does Previous Trial History Modulate the Joint Effects of Stimulus Quality and Word Frequency?

Science.gov (United States)

O'Malley, Shannon; Besner, Derek

2013-01-01

No one would argue with the proposition that how we process events in the world is strongly affected by our experience. Nonetheless, recent experience (e.g., from the previous trial) is typically not considered in the analysis of timed cognitive performance in the laboratory. Masson and Kliegl (2013) reported that, in the context of the lexical…

75 FR 25137 - Changes to Standard Numbering System, Vessel Identification System, and Boating Accident Report...

Science.gov (United States)

2010-05-07

...-2003-14963] RIN 1625-AB45 Changes to Standard Numbering System, Vessel Identification System, and... System (SNS), the Vessel Identification System (VIS), and casualty reporting; require validation of... Standard Numbering System U.S.C. United States Code VIS Vessel Identification System III. Background Coast...

Mediastinal involvement in lymphangiomatosis: a previously unreported MRI sign

Energy Technology Data Exchange (ETDEWEB)

Shah, Vikas; Shah, Sachit; Barnacle, Alex; McHugh, Kieran [Great Ormond Street Hospital for Children, Department of Radiology, London (United Kingdom); Sebire, Neil J. [Great Ormond Street Hospital for Children, Department of Histopathology, London (United Kingdom); Brock, Penelope [Great Ormond Street Hospital for Children, Department of Oncology, London (United Kingdom); Harper, John I. [Great Ormond Street Hospital for Children, Department of Dermatology, London (United Kingdom)

2011-08-15

Multifocal lymphangiomatosis is a rare systemic disorder affecting children. Due to its rarity and wide spectrum of clinical, histological and imaging features, establishing the diagnosis of multifocal lymphangiomatosis can be challenging. The purpose of this study was to describe a new imaging sign in this disorder: paraspinal soft tissue and signal abnormality at MRI. We retrospectively reviewed the imaging, clinical and histopathological findings in a cohort of eight children with thoracic involvement from this condition. Evidence of paraspinal chest disease was identified at MRI and CT in all eight of these children. The changes comprise heterogeneous intermediate-to-high signal parallel to the thoracic vertebrae on T2-weighted sequences at MRI, with abnormal paraspinal soft tissue at CT and plain radiography. Multifocal lymphangiomatosis is a rare disorder with a broad range of clinicopathological and imaging features. MRI allows complete evaluation of disease extent without the use of ionising radiation and has allowed us to describe a previously unreported imaging sign in this disorder, namely, heterogeneous hyperintense signal in abnormal paraspinal tissue on T2-weighted images. (orig.)

Correlated compositional and mineralogical investigations at the Chang'e-3 landing site.

Science.gov (United States)

Ling, Zongcheng; Jolliff, Bradley L; Wang, Alian; Li, Chunlai; Liu, Jianzhong; Zhang, Jiang; Li, Bo; Sun, Lingzhi; Chen, Jian; Xiao, Long; Liu, Jianjun; Ren, Xin; Peng, Wenxi; Wang, Huanyu; Cui, Xingzhu; He, Zhiping; Wang, Jianyu

2015-12-22

The chemical compositions of relatively young mare lava flows have implications for the late volcanism on the Moon. Here we report the composition of soil along the rim of a 450-m diameter fresh crater at the Chang'e-3 (CE-3) landing site, investigated by the Yutu rover with in situ APXS (Active Particle-induced X-ray Spectrometer) and VNIS (Visible and Near-infrared Imaging Spectrometer) measurements. Results indicate that this region's composition differs from other mare sample-return sites and is a new type of mare basalt not previously sampled, but consistent with remote sensing. The CE-3 regolith derived from olivine-normative basaltic rocks with high FeO/(FeO+MgO). Deconvolution of the VNIS data indicates abundant high-Ca ferropyroxene (augite and pigeonite) plus Fe-rich olivine. We infer from the regolith composition that the basaltic source rocks formed during late-stage magma-ocean differentiation when dense ferropyroxene-ilmenite cumulates sank and mixed with deeper, relatively ferroan olivine and orthopyroxene in a hybridized mantle source.

A CHANGE DETECTION AND RESOURCE-AWARE DATA SENSING APPROACHES FOR IMPROVING THE REPORTING PROTOCOL MECHANISM FOR MOBILE USER

Directory of Open Access Journals (Sweden)

annisaa sri indrawanti

2015-08-01

Full Text Available Update mechanism is an important process that relays information to the end-user by sending the data from the client to the server. There are several kinds of update mechanism that are used, one of them is reporting protocol. Reporting protocol sends the data from the client to the server continuously in a certain time interval. Reporting protocol occasionally sends the same information repeatedly to the end-user and sometimes the data aren’t needed by the end-user. This is an issue, because it can cause a large amount of bandwidth usage. In this research, we have developed an improvement of the reporting protocol mechanism for mobile user using change detection and resource-aware data sensing to minimize the bandwidth and resource usage. The improvement of reporting protocol that is implemented reduces frequency of data transfer with the prediction of the changes in user activity and position. The prediction is used as a trigger when the data is about to be sent. The results have shown that the adaptive reporting protocol could improve the performance of the overall reporting protocol. This is shown by the improvement of the bandwidth efficiency up to 36-97%, memory efficiency at 1.5-6% and battery efficiency at 7-13%.

Absence of psilocybin in species of fungi previously reported to contain psilocybin and related tryptamine derivatives

NARCIS (Netherlands)

Stijve, T.; Kuyper, Th.W.

1988-01-01

Seven taxa of agarics reported in literature to contain psilocybin (viz. Psathyrella candolleana, Gymnopilus spectabilis, G. fulgens, Hygrocybe psittacina var. psittacina and var. californica, Rickenella fibula, R. swartzii) have been analysed for psilocybin and related tryptamines with negative

Examining patterns of change in the critical thinking skills of graduate nursing students.

Science.gov (United States)

McMullen, Maureen A; McMullen, William F

2009-06-01

Although critical thinking in undergraduate nursing education has been explored in depth, little is known about the critical thinking skills of graduate nursing students. Prior research on change in critical thinking scores is based primarily on pretest and posttest assessments that provide minimal information about change. This study used individual growth modeling to investigate how critical thinking skills change during a 2-year graduate nurse program. Scores from the evaluation, inference, and analysis subscales of the California Critical Thinking Skills Test comprised the empirical growth record. Change in the three critical thinking skills was more dynamic than that reported in previous studies. Patterns of change differed by critical thinking skill and in relation to students' initial critical thinking skill levels at program entry.

Quality appraisal of generic self-reported instruments measuring health-related productivity changes: a systematic review

Science.gov (United States)

2014-01-01

Background Health impairments can result in disability and changed work productivity imposing considerable costs for the employee, employer and society as a whole. A large number of instruments exist to measure health-related productivity changes; however their methodological quality remains unclear. This systematic review critically appraised the measurement properties in generic self-reported instruments that measure health-related productivity changes to recommend appropriate instruments for use in occupational and economic health practice. Methods PubMed, PsycINFO, Econlit and Embase were systematically searched for studies whereof: (i) instruments measured health-related productivity changes; (ii) the aim was to evaluate instrument measurement properties; (iii) instruments were generic; (iv) ratings were self-reported; (v) full-texts were available. Next, methodological quality appraisal was based on COSMIN elements: (i) internal consistency; (ii) reliability; (iii) measurement error; (iv) content validity; (v) structural validity; (vi) hypotheses testing; (vii) cross-cultural validity; (viii) criterion validity; and (ix) responsiveness. Recommendations are based on evidence syntheses. Results This review included 25 articles assessing the reliability, validity and responsiveness of 15 different generic self-reported instruments measuring health-related productivity changes. Most studies evaluated criterion validity, none evaluated cross-cultural validity and information on measurement error is lacking. The Work Limitation Questionnaire (WLQ) was most frequently evaluated with moderate respectively strong positive evidence for content and structural validity and negative evidence for reliability, hypothesis testing and responsiveness. Less frequently evaluated, the Stanford Presenteeism Scale (SPS) showed strong positive evidence for internal consistency and structural validity, and moderate positive evidence for hypotheses testing and criterion validity. The

Reverse arthroplasty for osteoarthritis and rotator cuff deficiency after previous surgery for recurrent anterior shoulder instability.

Science.gov (United States)

Raiss, Patric; Zeifang, Felix; Pons-Villanueva, Juan; Smithers, Christopher J; Loew, Markus; Walch, Gilles

2014-07-01

Osteoarthritis in combination with rotator cuff deficiency following previous shoulder stabilisation surgery and after failed surgical treatment for chronic anterior shoulder dislocation is a challenging condition. The aim of this study was to analyse the results of reverse shoulder arthroplasty in such patients. Thirteen patients with a median follow-up of 3.5 (range two to eight) years and a median age of 70 (range 48-82) years were included. In all shoulders a tear of at least one rotator cuff tendon in combination with osteoarthritis was present at the time of arthroplasty. The Constant score, shoulder flexion and external and internal rotation with the elbow at the side were documented pre-operatively and at the final follow-up. Pre-operative, immediate post-operative and final follow-up radiographs were analysed. All complications and revisions were documented. Twelve patients were either satisfied or very satisfied with the procedure. The median Constant score increased from 26 points pre-operatively to 67 points at the final follow-up (p = 0.001). The median shoulder flexion increased significantly from 70° to 130° and internal rotation from two to four points (p = 0.002). External rotation did not change significantly (p = 0.55). Glenoid notching was present in five cases and was graded as mild in three cases and moderate in two. One complication occurred leading to revision surgery. Reverse arthroplasty leads to high satisfaction rates for patients with osteoarthritis and rotator cuff deficiency who had undergone previous shoulder stabilisation procedures. The improvements in clinical outcome as well as the radiographic results seem to be comparable with those of other studies reporting on the outcome of reverse shoulder arthroplasty for other conditions.

Plutonium carbonate speciation changes as measured in dilute solutions with photoacoustic spectroscopy: Yucca Mountain Site Characterization Program Milestone report 3350

International Nuclear Information System (INIS)

Tait, C.D.; Ekberg, S.A.; Palmer, P.D.; Morris, D.E.

1995-05-01

The stability fields for dilute Pu-carbonate species versus pH (8.4 to 12.0) and total carbonate concentrations (3 mM to 1.0 M) have been mapped-out using photoacoustic absorption spectroscopy (PAS). At least four different plutonium species, characterized by absorption peaks at 486, 492, 500, and 513 rim, have been found. A redox change to a Pu(VI) complex can not account for the speciation change associated with the first two spectra (486 and 492 nm peaks). Moreover, the data are consistent with what is predicted from a previous YMP milestone. This previous study was performed under very different conditions of plutonium concentration and carbonate/pH changes, and extension of these conditions to much lower Pu concentrations and to more neutral pHs was made possible with PAS spectroscopy. These new results reinforce the previous results by extending the range of direct observation and by eliminating other possibilities such as dimerization/polymerization reactions. As bicarbonate concentration is increased from .01 M to 1.0 M at pH=8.4 to 8.9, predominately [Pu(OH) x+1 (CO 3 ) y ] 4-(x+2y) (492 nm peak) is converted to [Pu(OH) x (CO 3 ) y+l ] 4-(x+2y+2) (486 nm peak). The starting stoichiometry (x and y values) remain undetermined, but the effect of ionic strength and temperature indicate that the 486 nm species is highly charged, and therefore x+2y≥3. The temperature effect on the equilibrium between these two species was also investigated, with the species giving rise to the 486 nm peak reversibly losing importance at elevated (50 and 75 degrees C temperatures)

Absence of psilocybin in species of fungi previously reported to contain psilocybin and related tryptamine derivatives

OpenAIRE

Stijve, T.; Kuyper, Th.W.

1988-01-01

Seven taxa of agarics reported in literature to contain psilocybin (viz. Psathyrella candolleana, Gymnopilus spectabilis, G. fulgens, Hygrocybe psittacina var. psittacina and var. californica, Rickenella fibula, R. swartzii) have been analysed for psilocybin and related tryptamines with negative results.

Outcomes after radical prostatectomy in men receiving previous pelvic radiation for non-prostate malignancies.

Science.gov (United States)

Masterson, Timothy A; Wedmid, Alexei; Sandhu, Jaspreet S; Eastham, James A

2009-08-01

To report the perioperative and functional outcomes of nine patients treated at our institution who had radical prostatectomy (RP) after previous pelvic radiotherapy (RT) for non-prostate malignancies. From 1993 to 2007, nine patients had RP after external beam RT for testicular seminoma (six), anorectal cancer (two) and colon cancer (one). Clinical information was obtained from a prospective prostate cancer database. RP was completed with no identifiable injury to adjacent structures in all nine patients. Four patients had significant pelvic fibrosis, and three required bilateral neurovascular bundle (NVB) resection. The NVB was preserved in the remaining six patients, four with good preoperative erectile function. However, no patient recovered erectile function after RP at a median (range) follow-up of 75 (12-172) months. Of seven men continent before RP, four required one or fewer pads daily and three were completely dry, achieving complete urinary control at a median (range) time of 7.5 (2-20) months. Two patients developed an anastomotic stricture, one being associated with concomitant ureteric stricture. RP after pelvic RT for non-prostate malignancies was not associated with increased intraoperative morbidity. However, rates of anastomotic stricture, erectile dysfunction and urinary incontinence appeared to be higher than those reported after RP in men with no previous RT, and comparable with those seen in the salvage RP setting.

Patient and parental self-reports of executive functioning in a sample of young female adolescents with anorexia nervosa before and after cognitive remediation therapy.

Science.gov (United States)

Dahlgren, Camilla Lindvall; Lask, Bryan; Landrø, Nils Inge; Rø, Øyvind

2014-01-01

Previous studies assessing the potency of cognitive remediation therapy (CRT) have largely focused on performance-based assessments and how these change during the course of the intervention. Little is known of behavioural manifestations of such changes, and no previous studies have studied parental reports before and after CRT. Patient and parental self-reports of executive function using the Behaviour Rating Inventory of Executive Function (BRIEF) were obtained for 17 adolescent patients in treatment for anorexia nervosa before and after CRT. Results indicated that patients scored significantly lower on the BRIEF shift subscale after CRT, whereas parental reports revealed significantly lower scores on the shift and emotional control subscales, and on the two composite indices Behavioural Regulation Index and Global Executive Composite. Case-wise comparisons support variations in executive functions in adolescents with anorexia nervosa. Changes are evaluated in light of the relationship between patients and parents and with regard to the limitations of the study design. Copyright © 2013 John Wiley & Sons, Ltd and Eating Disorders Association.

European Climate Change Programme. Working Group II. Impacts and Adaptation. Water Management. Sectoral Report

International Nuclear Information System (INIS)

2007-03-01

Adaptation is a new policy area for the European climate change policy. The Impacts and Adaptation Workgroup has been set up as part of European Climate Change Programme (ECCP II). The main objective of the workgroup is to explore options to improve Europe's resilience to Climate Change Impacts, to encourage the integration of climate change adaptation into other policy areas at the European, national and regional level and to define the role of EU-wide policies complementing action by Member States. The aim of this initial programme of work is to identify good practice in the development of adaptation policy and foster learning from different sectoral experiences and explore a possible EU role in adaptation policies. The Commission has led a series of 10 sectoral meetings looking at adaptation issues for different sectors. One of these meetings looked at the impacts on the water cycle and water resources management and prediction of extreme events in particular. This report summarises the state of play in the Water Resources sector in relation to adaptation to climate change on the basis of the information gathered at the stakeholder meeting on 11 April, 2006

The Climate Science Special Report: Detection and Attribution

Science.gov (United States)

Wehner, M. F.

2017-12-01

The Climate Science Special Report reiterates previous findings about the human influence on global mean surface air temperature with the statement "…it is extremely likely that human activities, especially emissions of greenhouse gases, are the dominant cause of the observed warming since the mid 20th century. For the warming over the last century, there is no convincing alternative explanation supported by the extent of the observational evidence." This is a statement made with high confidence and supported by multiple lines of evidence. The report also assesses the latest developments in the field of probabilistic extreme event attribution—the quantification of the influence of anthropogenic climate change on individual extreme weather events—with a focus on those recent events within the United States that have been analyzed. Thirty different events within the US are reported on including heat waves, cold snaps, wet seasons, individual storms and droughts. Most but not all of the individual US events studied revealed an influence from human induced changes to the climate system.

Climate change science compendium 2009

Energy Technology Data Exchange (ETDEWEB)

McMullen, C.P.; Jabbour, J.

2009-09-15

In a matter of a few weeks' time, governments will gather in Copenhagen, Denmark, for a crucial UN climate convention meeting. Many governments and stakeholders have requested an annual snapshot of how the science has been evolving since the publication of the IPCC's landmark fourth assessment in advance of the panel's next one in 2014. This Climate Change Science Compendium, based on the wealth of peerreviewed research published by researchers and institutions since 2006, has been compiled by UNEP in response to that request. The findings indicate that ever more rapid environmental change is underway with the pace and the scale of climate change accelerating, along with the confidence among researchers in their forecasts. The Arctic, with implications for the globe, is emerging as an area of major concern. There is growing evidence that the ice there is melting far faster than had been previously supposed. Mountains glaciers also appear to be retreating faster. Scientists now suggest that the Arctic could be virtually ice free in September of 2037 and that a nearly ice-free September by 2028 is well within the realms of possibility. Recent findings also show that significant warming extends well beyond the Antarctic Peninsula to cover most of West Antarctica, an area of warming much larger than previously reported. The impact on the Earth's multi-trillion dollar ecosystems is also a key area of concern. Under a high emission scenario-the one that most closely matches current trends-12-39 per cent of the planet's terrestrial surface could experience novel climate conditions and 10-48 per cent could suffer disappearing climates by 2100. Rising levels of aridity are also concentrating scientific minds. New research indicates that by the end of the 21st century the Mediterranean region will also experience much more severe increases in aridity than previously estimated rendering the entire region, but particularly the southern Mediterranean

Determinants of Behavior Change Intention Among Heterosexual Thai Males Diagnosed with Sexually Transmitted Diseases.

Science.gov (United States)

Thato, Ratsiri; Daengsaard, Ekkachai

2016-11-01

This study sought to identify factors associated with intention to change sexual practices among heterosexual Thai males diagnosed with sexually transmitted infections (STIs). STI clinic patients (n = 247) reported their sexual behaviors and condom use during the previous 3 months. STI and HIV knowledge, motivation to change sexual practices, and behavioral skills were assessed. Then, self-reported behavior change intention, including consistent condom use, reducing number of sexual partners, not using drugs and alcohol when having sex, and refusal of condomless sex, was examined. Consistent condom use in the past 3 months by Thai males diagnosed with STIs was low across all types of sexual partners (lover 13.8%, casual partner 14.9%, and sex worker 2.5%). Risk reduction self-efficacy (p behavior change intention. Significant predictors of behavior change intention were risk reduction self-efficacy (p behavior change intention variance. Intervention aimed at enhancing motivation and behavioral skills to adopt preventive behaviors should be developed to prevent recurrent STIs, including HIV infection, among heterosexual Thai males diagnosed with STIs.