WorldWideScience

Sample records for previously developed potentials

  1. Predictive factors for the development of diabetes in women with previous gestational diabetes mellitus

    DEFF Research Database (Denmark)

    Damm, P.; Kühl, C.; Bertelsen, Aksel

    1992-01-01

    OBJECTIVES: The purpose of this study was to determine the incidence of diabetes in women with previous dietary-treated gestational diabetes mellitus and to identify predictive factors for development of diabetes. STUDY DESIGN: Two to 11 years post partum, glucose tolerance was investigated in 241...... women with previous dietary-treated gestational diabetes mellitus and 57 women without previous gestational diabetes mellitus (control group). RESULTS: Diabetes developed in 42 (17.4%) women with previous gestational diabetes mellitus (3.7% insulin-dependent diabetes mellitus and 13.7% non...... of previous patients with gestational diabetes mellitus in whom plasma insulin was measured during an oral glucose tolerance test in late pregnancy a low insulin response at diagnosis was found to be an independent predictive factor for diabetes development. CONCLUSIONS: Women with previous dietary...

  2. Milestone report on MD potential development for uranium silicide

    International Nuclear Information System (INIS)

    Yu, Jianguo; Zhang, Yongfeng; Hales, Jason Dean

    2016-01-01

    This report summarizes the progress on the interatomic potential development of triuranium-disilicide (U 3 Si 2 ) for molecular dynamics (MD) simulations. The development is based on the Tersoff type potentials for single element U and Si. The Si potential is taken from the literature and a Tersoff type U potential is developed in this project. With the primary focus on the U 3 Si 2 phase, some other U-Si systems such as U 3 Si are also included as a test of the transferability of the potentials for binary U-Si phases. Based on the potentials for unary U and Si, two sets of parameters for the binary U-Si system are developed using the Tersoff mixing rules and the cross-term fitting, respectively. The cross-term potential is found to give better results on the enthalpy of formation, lattice constants and elastic constants than those produced by the Tersoff mixing potential, with the reference data taken from either experiments or density functional theory (DFT) calculations. In particular, the results on the formation enthalpy and lattice constants for the U 3 Si 2 phase and lattice constants for the high temperature U 3 Si (h-U 3 Si) phase generated by the cross-term potential agree well with experimental data. Reasonable agreements are also reached on the elastic constants of U 3 Si 2 , on the formation enthalpy for the low temperature U 3 Si (m-U 3 Si) and h-U 3 Si phases, and on the lattice constants of m-U 3 Si phase. All these phases are predicted to be mechanically stable. The unary U potential is tested for three metallic U phases (α, β, γ). The potential is found capable to predict the cohesive energies well against experimental data for all three phases. It matches reasonably with previous experiments on the lattice constants and elastic constants of αU.

  3. Milestone report on MD potential development for uranium silicide

    Energy Technology Data Exchange (ETDEWEB)

    Yu, Jianguo [Idaho National Lab. (INL), Idaho Falls, ID (United States). Fuel Modeling and Simulation Dept.; Zhang, Yongfeng [Idaho National Lab. (INL), Idaho Falls, ID (United States). Fuel Modeling and Simulation Dept.; Hales, Jason Dean [Idaho National Lab. (INL), Idaho Falls, ID (United States). Fuel Modeling and Simulation Dept.

    2016-03-01

    This report summarizes the progress on the interatomic potential development of triuranium-disilicide (U3Si2) for molecular dynamics (MD) simulations. The development is based on the Tersoff type potentials for single element U and Si. The Si potential is taken from the literature and a Tersoff type U potential is developed in this project. With the primary focus on the U3Si2 phase, some other U-Si systems such as U3Si are also included as a test of the transferability of the potentials for binary U-Si phases. Based on the potentials for unary U and Si, two sets of parameters for the binary U-Si system are developed using the Tersoff mixing rules and the cross-term fitting, respectively. The cross-term potential is found to give better results on the enthalpy of formation, lattice constants and elastic constants than those produced by the Tersoff mixing potential, with the reference data taken from either experiments or density functional theory (DFT) calculations. In particular, the results on the formation enthalpy and lattice constants for the U3Si2 phase and lattice constants for the high temperature U3Si (h-U3Si) phase generated by the cross-term potential agree well with experimental data. Reasonable agreements are also reached on the elastic constants of U3Si2, on the formation enthalpy for the low temperature U3Si (m-U3Si) and h-U3Si phases, and on the lattice constants of m-U3Si phase. All these phases are predicted to be mechanically stable. The unary U potential is tested for three metallic U phases (α, β, γ). The potential is found capable to predict the cohesive energies well against experimental data for all three phases. It matches reasonably with previous experiments on the lattice constants and elastic constants of αU.

  4. Labor potential: enhancing its development

    Directory of Open Access Journals (Sweden)

    O.P. Melnichuk

    2016-06-01

    Full Text Available This publication presents the views of the author about the need to expand research of labor potential, estimation of quantitative indicators and qualitative characteristics at the individual, regional levels and the state as a whole to develop the mechanisms of its development. The existing methods of labour potential assessment are mainly based on the probable approach taking into account external and internal factors. In the case of assessment of labour potential of a single enterprise for the most suitable for this production method the mechanisms of its development can be worked out. However, for the state under a certain depreciation of the resource, property, financial and other potentials, aggressive manifestations of the crisis phenomena, processes etc. to resolve urgent is the problem of enhancing the development of qualitative characteristics of labor potential at all its levels. In this context it is important to exploit the potential of domestic education and science which now continue to be reformed for the sake of achieving European standards, using the advanced experience of other countries. Every means of legal, financial, managerial, and organizational impact should be used for this.

  5. Potentiality, Development Ideals, and Realities of Social Work

    DEFF Research Database (Denmark)

    Ringø, Pia

    2018-01-01

    a focus on “the healthy part”, resources, empowerment, and the will to imagine “the future of the future” and “the desirable present of the present” (Andersen & Poors, 2016). The aspiration to abolish previous understandings of welfare as they have developed in Denmark over the past 40-50 years is central...... as a question of providing stability in a changeable world, or in the lives of people who are vulnerable and exposed . Today the problem is the inherent tendency to provide too much stability, habitual behavior and inertia. My argument is that the vision of potentialization is currently expressing itself...... to this development. But what is the news in relation to social work? In the article I approach this question by showing 1: how potentionalization influences the perception as well as the concrete distribution of social problems. 2: how potentionalization influences the concrete practices of welfare services...

  6. Mentoring to develop research selfefficacy, with particular reference to previously disadvantaged individuals

    OpenAIRE

    S. Schulze

    2010-01-01

    The development of inexperienced researchers is crucial. In response to the lack of research self-efficacy of many previously disadvantaged individuals, the article examines how mentoring can enhance the research self-efficacy of mentees. The study is grounded in the self-efficacy theory (SET) – an aspect of the social cognitive theory (SCT). Insights were gained from an in-depth study of SCT, SET and mentoring, and from a completed mentoring project. This led to the formulation of three basi...

  7. The Development Potential in the System of Potentials of an Industrial Enterprise

    Directory of Open Access Journals (Sweden)

    Shpak Sergiy O.

    2018-03-01

    Full Text Available The aim of the article is to clarify the content and formulate a methodologically rigorous definition of the concept of enterprise development as a key category of management theory for restructuring industrial enterprises that provides the basis for a constructive definition of the concept of development potential and its place in the system of enterprise potentials. It is substantiated that the interpretation of the concept of enterprise development that is consistent with the philosophical concept of development should accumulate the concepts of competitiveness of an enterprise, as the ability to generate an acceptable profit on a long-term basis; the potential of an enterprise, as the ability to perform its basic activity characterizing the cumulative result of such activity, its marginal opportunities; the role of the structure of the enterprise as a system in the formation of its ultimate capabilities (potentials. It is shown that these requirements are met by the definition of the development process as a process of a purposeful transfer of the enterprise to a qualitatively new state described by broader opportunities for generating profits under the forecast conditions. At the same time, the structural adaptation of the enterprise to the new operating conditions is a tool for realizing the development process, which indicates the equivalence of the concepts of structural adaptability of an enterprise and its development potential. It is substantiated that the competitiveness of an enterprise is determined by its economic potential and development potential, which form the highest level of the hierarchy of potentials, the construction of which is possible in the course of decomposition of these potentials into their components according to the type of activity of the enterprise.

  8. Development of a potential based code for MHD analysis of LLCB TBM

    International Nuclear Information System (INIS)

    Bhuyan, P.J.; Goswami, K.S.

    2010-01-01

    A two dimensional solver is developed for MHD flows with low magnetic Reynolds' number based on the electrostatic potential formulation for the Lorentz forces and current densities which will be used to calculate the MHD pressure drop inside the channels of liquid breeder based Test Blanket Modules (TBMs). The flow geometry is assumed to be rectangular and perpendicular to the flow direction, with flow and electrostatic potential variations along the flow direction neglected. A structured, non-uniform, collocated grid is used in the calculation, where the velocity (u), pressure (p) and electrostatic potential (φ) are calculated at the cell centers, whereas the current densities are calculated at the cell faces. Special relaxation techniques are employed in calculating the electrostatic potential for ensuring the divergence-free condition for current density. The code is benchmarked over a square channel for various Hartmann numbers up to 25,000 with and without insulation coatings by (i) comparing the pressure drop with the approximate analytical results found in literature and (ii) comparing the pressure drop with the ones obtained in our previous calculations based on the induction formulation for the electromagnetic part. Finally the code is used to determine the MHD pressure drop in case of LLCB TBM. The code gives similar results as obtained by us in our previous calculations based on the induction formulation. However, the convergence is much faster in case of potential based code.

  9. Postpartum IGF-I and IGFBP-2 levels are prospectively associated with the development of type 2 diabetes in women with previous gestational diabetes mellitus.

    Science.gov (United States)

    Lappas, M; Jinks, D; Shub, A; Willcox, J C; Georgiou, H M; Permezel, M

    2016-12-01

    Women with previous gestational diabetes mellitus (GDM) are at greater risk of developing type 2 diabetes. In the general population, the insulin-like growth factor (IGF) system has been implicated in the development of type 2 diabetes. The aim of this study was to determine if circulating IGF-I, IGF-II, IGFBP-1 and IGFBP-2 levels 12weeks following a GDM pregnancy are associated with an increased risk of developing type 2 diabetes. IGF-I, IGF-II, IGFBP-1 and IGFBP-2 levels were measured in 98 normal glucose tolerant women, 12weeks following an index GDM pregnancy using enzyme immunoassay. Women were assessed for up to 10years for the development of overt type 2 diabetes. Among the 98 women with previous GDM, 21 (21%) developed diabetes during the median follow-up period of 8.5years. After adjusting for age and BMI, IGF-I and IGFBP-2 were significantly associated with the development of type 2 diabetes. In a clinical model of prediction of type 2 diabetes that included age, BMI, pregnancy fasting glucose and postnatal fasting glucose, the addition of IGF-I and IGFBP-2 resulted in an improvement in the net reclassification index of 17.8%. High postpartum IGF-I and low postpartum IGFBP-2 levels are a significant risk factor for the development of type 2 diabetes in women with a previous history of GDM. This is the first report that identifies IGF-I and IGFBP-2 as a potential biomarker for the prediction of type 2 diabetes in women with a history of GDM. Copyright © 2016 Elsevier Masson SAS. All rights reserved.

  10. Development potential for hydropower

    International Nuclear Information System (INIS)

    Laufer, F.; Groetzinger, S.; Peter, M.; Schmutz, A.

    2004-11-01

    This comprehensive report for the Swiss Federal Office of Energy (SFOE) takes a look at the potential for the development of hydropower in Switzerland. The report updates the energy perspectives made ten years earlier. An overview of Swiss electricity production and consumption is presented and the proportion provided by hydropower is noted. Figures on installed capacity and import/export quantities are presented and discussed. Technological developments and the economical frameworks involved are discussed, as are regulatory measures that can be taken. Theoretical and technically realisable potentials for increased use of hydropower are discussed. The methods used to do this are examined. Strategies and measures to be taken are listed and discussed. An appendix includes data sheets on power plant modelling, including examples

  11. Global assessment of research and development for algae biofuel production and its potential role for sustainable development in developing countries

    International Nuclear Information System (INIS)

    Adenle, Ademola A.; Haslam, Gareth E.; Lee, Lisa

    2013-01-01

    The possibility of economically deriving fuel from cultivating algae biomass is an attractive addition to the range of measures to relieve the current reliance on fossil fuels. Algae biofuels avoid some of the previous drawbacks associated with crop-based biofuels as the algae do not compete with food crops. The favourable growing conditions found in many developing countries has led to a great deal of speculation about their potentials for reducing oil imports, stimulating rural economies, and even tackling hunger and poverty. By reviewing the status of this technology we suggest that the large uncertainties make it currently unsuitable as a priority for many developing countries. Using bibliometric and patent data analysis, we indicate that many developing countries lack the human capital to develop their own algae industry or adequately prepare policies to support imported technology. Also, we discuss the potential of modern biotechnology, especially genetic modification (GM) to produce new algal strains that are easier to harvest and yield more oil. Controversy surrounding the use of GM and weak biosafety regulatory system represents a significant challenge to adoption of GM technology in developing countries. A range of policy measures are also suggested to ensure that future progress in algae biofuels can contribute to sustainable development. - Highlights: • Algae biofuels can make positive contribution to sustainable development in developing countries. • Bibliometric and patent data indicate that many lack the human capital to develop their own algae industry. • Large uncertainties make algae biofuels currently unsuitable as a priority for many developing countries

  12. Luminal progenitors restrict their lineage potential during mammary gland development.

    Science.gov (United States)

    Rodilla, Veronica; Dasti, Alessandro; Huyghe, Mathilde; Lafkas, Daniel; Laurent, Cécile; Reyal, Fabien; Fre, Silvia

    2015-02-01

    The hierarchical relationships between stem cells and progenitors that guide mammary gland morphogenesis are still poorly defined. While multipotent basal stem cells have been found within the myoepithelial compartment, the in vivo lineage potential of luminal progenitors is unclear. Here we used the expression of the Notch1 receptor, previously implicated in mammary gland development and tumorigenesis, to elucidate the hierarchical organization of mammary stem/progenitor cells by lineage tracing. We found that Notch1 expression identifies multipotent stem cells in the embryonic mammary bud, which progressively restrict their lineage potential during mammary ductal morphogenesis to exclusively generate an ERαneg luminal lineage postnatally. Importantly, our results show that Notch1-labelled cells represent the alveolar progenitors that expand during pregnancy and survive multiple successive involutions. This study reveals that postnatal luminal epithelial cells derive from distinct self-sustained lineages that may represent the cells of origin of different breast cancer subtypes.

  13. Development of an inter-atomic potential for the Pd-H binary system.

    Energy Technology Data Exchange (ETDEWEB)

    Zimmerman, Jonathan A.; Hoyt, Jeffrey John (McMaster University, Hamilton, Ontario, Canada); Leonard, Francois Leonard; Griffin, Joshua D.; Zhou, Xiao Wang

    2007-09-01

    Ongoing research at Sandia National Laboratories has been in the area of developing models and simulation methods that can be used to uncover and illuminate the material defects created during He bubble growth in aging bulk metal tritides. Previous efforts have used molecular dynamics calculations to examine the physical mechanisms by which growing He bubbles in a Pd metal lattice create material defects. However, these efforts focused only on the growth of He bubbles in pure Pd and not on bubble growth in the material of interest, palladium tritide (PdT), or its non-radioactive isotope palladium hydride (PdH). The reason for this is that existing inter-atomic potentials do not adequately describe the thermodynamics of the Pd-H system, which includes a miscibility gap that leads to phase separation of the dilute (alpha) and concentrated (beta) alloys of H in Pd at room temperature. This document will report the results of research to either find or develop inter-atomic potentials for the Pd-H and Pd-T systems, including our efforts to use experimental data and density functional theory calculations to create an inter-atomic potential for this unique metal alloy system.

  14. Assessment and management of building enterprise development potential

    Directory of Open Access Journals (Sweden)

    Елена Игоревна Угодникова

    2015-11-01

    Full Text Available The article is devoted to the development of the generalized integrated criterion of the evaluation of building enterprise development potential. The developed indicator is based on the potential structuring, accounting weighting factors of each structural elements and the possibility of building enterprise capital raising. The algorithm of the potential evaluation and the scheme of the management of building enterprise development potential with accounting future possibilities and hidden resources of business entities are proposed

  15. Talent development – dealing with potentiality

    DEFF Research Database (Denmark)

    Olesen, Jesper; Nielsen, Jens Christian; Søndergaard, Dorte Marie

    2017-01-01

    - and a talent development environment which, in their encounter, creates an affect that produces talent. Based on a case study on Jamie, a badminton player, we show that the combined talent/development assemblage is capable of maintaining a talent despite the fact that Jamie has a long-term injury...... and is completely unable to play badminton for long periods of time. We argue that talent development is a particular way of handling potentiality which, in the struggle to achieve the ultimate goal of excellence, results in a number of affects: it translates potential into a singular talent; it enables...

  16. Developing simplified Regional Potential Evapotranspiration (PET ...

    African Journals Online (AJOL)

    Regional Potential Evapotranspiration (PET) estimation method was developed to estimate the potential evapotranspiration (reference evapotranspiration) over Abbay Basin as a function of basin maximum and minimum temperature, and modulated by site specific elevation data. The method is intended to estimate PET in ...

  17. Sub-Saharan hydroelectric power development potential

    International Nuclear Information System (INIS)

    Lazenby, J.B.C.

    1991-01-01

    Though evidencing a power demand which is amongst the lowest in the world, the sub-Saharan regions of Africa are blessed with an enormous hydroelectric power resource potential, which, if suitably developed and tapped, may become a source of economic electric energy for Europe. With the aid of numerous statistical supply and demand data, this paper surveys the marketing potential of this energy source in Africa. The analysis of future development prospects is carried out with reference to the local socio-economic framework

  18. Research Note Effects of previous cultivation on regeneration of ...

    African Journals Online (AJOL)

    We investigated the effects of previous cultivation on regeneration potential under miombo woodlands in a resettlement area, a spatial product of Zimbabwe's land reforms. We predicted that cultivation would affect population structure, regeneration, recruitment and potential grazing capacity of rangelands. Plant attributes ...

  19. Study of the methanization development potential in the Mayenne district (53)

    International Nuclear Information System (INIS)

    Duval, Valentin; Lemarie, Christophe; Geneau De Lamarliere, Laurent; Hubert, Cecile; Le Guen, Gaelle

    2011-06-01

    The first objective of this study is to determine the quantity of fermentable wastes produced by agricultural exploitations, agri-food industries and communities at the district scale, and to identify the main agricultural, industrial and community-based consumers of agricultural heat in order to ensure project profitability. A second objective, based on previous assessments, is to highlight possible methanization projects on the whole district territory, and to determine needed surfaces in relationship with the spreading of the digestate produced by these methanization projects. As far as the second objective is concerned, the report propose some generalities (project typologies, development criteria, produced energy, other potential wastes), presents different types of liquid phase or dry methanization (methodology, technology, costs), alternative scenarios, spreading potentials, and an environmental assessment (greenhouse emissions, impact on the natural and human environment). Several appendices are provided which contain data tables, maps of production assessments and of location distributions of installations

  20. Software development tools using GPGPU potentialities

    International Nuclear Information System (INIS)

    Dudnik, V.A.; Kudryavtsev, V.I.; Sereda, T.M.; Us, S.A.; Shestakov, M.V.

    2011-01-01

    The paper deals with potentialities of various up-to-date software development tools for making use of graphic processor (GPU) parallel computing resources. Examples are given to illustrate the use of present-day software tools for the development of applications and realization of algorithms for scientific-technical calculations performed by GPGPU. The paper presents some classes of hard mathematical problems of scientific-technical calculations, for which the GPGPU can be efficiently used. is possible. To reduce the time of calculation program development with the use of GPGPU capabilities, various dedicated programming systems and problem-oriented subroutine libraries are recommended. Performance parameters when solving the problems with and without the use of GPGPU potentialities are compared.

  1. Challenging previous conceptions of vegetarianism and eating disorders.

    Science.gov (United States)

    Fisak, B; Peterson, R D; Tantleff-Dunn, S; Molnar, J M

    2006-12-01

    The purpose of this study was to replicate and expand upon previous research that has examined the potential association between vegetarianism and disordered eating. Limitations of previous research studies are addressed, including possible low reliability of measures of eating pathology within vegetarian samples, use of only a few dietary restraint measures, and a paucity of research examining potential differences in body image and food choice motives of vegetarians versus nonvegetarians. Two hundred and fifty-six college students completed a number of measures of eating pathology and body image, and a food choice motives questionnaire. Interestingly, no significant differences were found between vegetarians and nonvegetarians in measures of eating pathology or body image. However, significant differences in food choice motives were found. Implications for both researchers and clinicians are discussed.

  2. HUMAN POTENTIAL AS A STRATEGIC FACTOR OF REGIONAL DEVELOPMENT

    Directory of Open Access Journals (Sweden)

    A.M. Korobeynikov

    2008-12-01

    Full Text Available The article gives an insight of human potential as the strategic factor of regional development. The matter of human potential and its role in regional reproducing process is considered; regional intellectual potential as an integral part of human potential is analysed. The author outlines major directions of active social policy, aimed to develop regional human potential.

  3. Mentoring to develop research selfefficacy, with particular reference to previously disadvantaged individuals

    Directory of Open Access Journals (Sweden)

    S. Schulze

    2010-07-01

    Full Text Available The development of inexperienced researchers is crucial. In response to the lack of research self-efficacy of many previously disadvantaged individuals, the article examines how mentoring can enhance the research self-efficacy of mentees. The study is grounded in the self-efficacy theory (SET – an aspect of the social cognitive theory (SCT. Insights were gained from an in-depth study of SCT, SET and mentoring, and from a completed mentoring project. This led to the formulation of three basic principles. Firstly, institutions need to provide supportive environmental conditions that facilitate research selfefficacy. This implies a supportive and efficient collective system. The possible effects of performance ratings and reward systems at the institution also need to be considered. Secondly, mentoring needs to create opportunities for young researchers to experience successful learning as a result of appropriate action. To this end, mentees need to be involved in actual research projects in small groups. At the same time the mentor needs to facilitate skills development by coaching and encouragement. Thirdly, mentors need to encourage mentees to believe in their ability to successfully complete research projects. This implies encouraging positive emotional states, stimulating self-reflection and self-comparison with others in the group, giving positive evaluative feedback and being an intentional role model.

  4. Development of an Internet-Administered Cognitive Behavior Therapy Program (ENGAGE) for Parents of Children Previously Treated for Cancer: Participatory Action Research Approach.

    Science.gov (United States)

    Wikman, Anna; Kukkola, Laura; Börjesson, Helene; Cernvall, Martin; Woodford, Joanne; Grönqvist, Helena; von Essen, Louise

    2018-04-18

    future studies testing and evaluating the intervention were discussed; consensus was not reached for all aspects. To the best of our knowledge, this study is the first use of a participatory action research approach to develop a psychological intervention for parents of children previously treated for cancer and to identify acceptable study procedures. Involvement of parents with lived experience was vital in the development of a potentially relevant and acceptable intervention for this population. ©Anna Wikman, Laura Kukkola, Helene Börjesson, Martin Cernvall, Joanne Woodford, Helena Grönqvist, Louise von Essen. Originally published in the Journal of Medical Internet Research (http://www.jmir.org), 18.04.2018.

  5. Developing Human Resources through Actualizing Human Potential

    Science.gov (United States)

    Clarken, Rodney H.

    2012-01-01

    The key to human resource development is in actualizing individual and collective thinking, feeling and choosing potentials related to our minds, hearts and wills respectively. These capacities and faculties must be balanced and regulated according to the standards of truth, love and justice for individual, community and institutional development,…

  6. Human potential development as a prerequisite of public policy efficiency

    Directory of Open Access Journals (Sweden)

    Polishchuk Iryna Viktorivna

    2014-12-01

    Full Text Available The article analyses the role of the public officers’ human potential for the efficiency of making public policy. It introduces features and criteria of human potential in the context of its development of civil service. The article designates some key directions for the development of human potential of public officers.

  7. Potential success factors in brand development

    DEFF Research Database (Denmark)

    Esbjerg, Lars; Grunert, Klaus G.; Poulsen, Carsten Stig

    2005-01-01

    to the marketing of the brand." The branding literature mentions many important aspects, factors, issues, brand requirements, steps, building blocks or guidelines for building strong brands. However, these are all quite general and abstract. Given the substantial body of literature on branding, surprisingly few......? This is the question we want to answer. More specifically, we want to identify potential success factors in building strong brands, understood as brands with high consumer-based brand equity. Keller (1993, p. 2) defined customer-based brand equity as "the differential effect of brand knowledge on consumer response...... of this paper is to identify potential success factors in developing strong brands and to test whether these factors can be used to discriminate between strong and weak brands. It does so through a review of the literature for potential success factors. Furthermore, to ensure that important factors have...

  8. No discrimination against previous mates in a sexually cannibalistic spider

    Science.gov (United States)

    Fromhage, Lutz; Schneider, Jutta M.

    2005-09-01

    In several animal species, females discriminate against previous mates in subsequent mating decisions, increasing the potential for multiple paternity. In spiders, female choice may take the form of selective sexual cannibalism, which has been shown to bias paternity in favor of particular males. If cannibalistic attacks function to restrict a male's paternity, females may have little interest to remate with males having survived such an attack. We therefore studied the possibility of female discrimination against previous mates in sexually cannibalistic Argiope bruennichi, where females almost always attack their mate at the onset of copulation. We compared mating latency and copulation duration of males having experienced a previous copulation either with the same or with a different female, but found no evidence for discrimination against previous mates. However, males copulated significantly shorter when inserting into a used, compared to a previously unused, genital pore of the female.

  9. Second malignancies in high-dose areas of previous tumor radiotherapy

    Energy Technology Data Exchange (ETDEWEB)

    Welte, Birgitta; Suhr, Peter; Bottke, Dirk; Bartkowiak, Detlef; Wiegel, Thomas [Dept. of Radiotherapy and Radiation Oncology, Univ. of Ulm (Germany); Doerr, Wolfgang [Dept. of Radiotherapy and Radiation Oncology, Radiobiology Lab., Univ. of Technology Dresden (Germany); Trott, Klaus Ruediger [UCL Cancer Centre, Univ. Coll. London (United Kingdom)

    2010-03-15

    Purpose: To characterize second tumors that developed in or near the high-dose areas of a previous radiotherapy, regarding their frequency, entities, latency, and dose dependence. Patients and Methods: 9,995/15,449 tumor patients of the Radiation Oncology Department in Ulm, Germany, treated between 1981 and 2003, survived at least 1 year after radiotherapy. By long-term follow-up and review of treatment documentation, 100 of them were identified who developed an independent second cancer in or near the irradiated first tumor site. Results: Major primary malignancies were breast cancer (27%), lymphoma (24%), and pelvic gynecologic tumors (17%). Main second tumors were carcinomas of the upper (18%) and lower (12%) gastrointestinal tract, head and neck tumors (10%), lymphoma (10%), breast cancer (9%), sarcoma (9%), and lung cancer (8%). Overall median second tumor latency was 7.4 years (1-42 years). For colorectal cancer it was 3.5 and for leukemia 4.3 years, but for sarcoma 11.7 and for breast cancer 17.1 years. The relatively frequent second tumors of the upper gastrointestinal tract were associated with median radiation doses of 24 Gy. By contrast, second colorectal cancer and sarcoma developed after median doses of 50 Gy. Conclusion: The 5- and 15-year probability to develop a histopathologically independent second tumor in or near the irradiated first tumor site, i.e., after intermediate or high radiation doses, was 0.5% and 2.2%, respectively. To identify potentially radiogenic second malignancies, a follow-up far beyond 5 years is mandatory. The incidence and potential dose-response relationship intermediate will be analyzed by a case-case and a case-control study of the Ulm data. (orig.)

  10. Local self-government potential in sustainable development of region providing

    Directory of Open Access Journals (Sweden)

    O. Y. Bobrovska

    2016-06-01

    Full Text Available Ongoing decentralization of power in Ukraine enhances abilities of each region to independently choose their development path and use their own resources. It requires reviewing and updating of mechanisms and instruments of local government and public administration projected to increase the sustainability of development. This necessitates further research of issues of this extremely complex phenomenon. The problem of sustainable development of the regions and their internal capacities over the past decades has attracted the attention of many Ukrainian scientists. They considered the question of the essence and characteristics of this phenomenon, categorical apparatus, and formed approaches to the assessment of the state etc. Existing scientific researchers provided an opportunity for better understanding and deepening of the issues of processes of development formation, becoming the basis for further research. The purpose of the article is the definition of the potential of local governments in the sustainable development of the region, finding approaches for improving management and rational use of resources to enhance the regional development. Development of regions is the scope of display of results and public nature of local self-government. However, the results which are achieved by regional development and its level of sustainability do not meet the needs of society. The results of ongoing reforms, their economic, environmental and social significance do not correspond to spent resources and efforts of society. Strategies of regions for the transition to sustainable development are not systematic. To search for answers and ways to address the issues of the article attempts to identify common root causes in the organization of local government, the underlying increase its impact in the direction of creating conditions and ensure the flow of sustainable regional development through research and their potential influential factors. It is

  11. Development potential for hydropower; Ausbaupotential der Wasserkraft

    Energy Technology Data Exchange (ETDEWEB)

    Laufer, F.; Groetzinger, S.; Peter, M.; Schmutz, A.

    2004-11-15

    This comprehensive report for the Swiss Federal Office of Energy (SFOE) takes a look at the potential for the development of hydropower in Switzerland. The report updates the energy perspectives made ten years earlier. An overview of Swiss electricity production and consumption is presented and the proportion provided by hydropower is noted. Figures on installed capacity and import/export quantities are presented and discussed. Technological developments and the economical frameworks involved are discussed, as are regulatory measures that can be taken. Theoretical and technically realisable potentials for increased use of hydropower are discussed. The methods used to do this are examined. Strategies and measures to be taken are listed and discussed. An appendix includes data sheets on power plant modelling, including examples

  12. Potentials of Local Economic Development in Aspect of Tourism

    OpenAIRE

    Viktória Csizmadiáné Czuppon; Edina Sáriné Csajka; Tamás Molnár

    2015-01-01

    The objective of the study is to introduce the potentials of local economic development in one of the least favoured micro regions, Tamási. The paper examines operating and planned activities at settlements of the micro region. The authors introduce local economic development activities that support tourism. The economic development planning in Tamási micro region has typically two directions. One of them is the utilisation of thermal water and the use of further potentials of the thermal bat...

  13. The potential for coalbed methane (CBM) development in Alberta

    International Nuclear Information System (INIS)

    2001-09-01

    This report presents fiscal and regulatory recommendations of the coalbed methane (CBM) Advisory Committee which consists of representatives from Alberta's oil and gas industry who participated in a study to determine the potential for coalbed methane development in the province. CBM is a natural gas produced as a by-product of the coal formation process. This study examined the CBM reserve base in Alberta along with the necessary steps and strategies required to develop it. There is increased interest in natural gas from Alberta's coal resources because of the forecast for reasonable natural gas prices coupled with an increase in energy demand. The remaining established natural gas reserves are estimated at 43 trillion cubic feet and unconventional supplies of natural gas will be needed by 2008 to meet this increasing demand. The recoverable reserves of CBM are estimated to be between 0 and 135 trillion cubic feet. This report discussed the following mitigation strategies suggested by industry that may applicable to CBM development in Alberta: (1) potential technical mitigation strategies, (2) potential land access and tenure strategies, (3) potential water disposal and diversion mitigation strategies, (4) potential non-technical mitigation strategies, and (5) potential economic mitigation strategies. The study concluded that since no two CBM basins are the same, it is necessary to have good baseline resource inventory data. It was also noted that evolving management, drilling and completion techniques will continue to enhance the economic understanding of Alberta's extensive coal beds. It was suggested that lessons from CBM development in the United States can be useful for development in Alberta since there are currently no publicly recognized commercial production of CBM in Alberta. 24 refs., 6 tabs., 25 figs

  14. Relationship between the public's belief in recovery, level of mental illness stigma, and previous contact.

    Science.gov (United States)

    Barczyk, Amanda N

    2015-01-01

    Disbelief exits that individuals who have a mental health condition are able to recover and fully function in life. This study analyzed 1,437 adults from the 2006 General Social Survey. Structural equation modeling (1) examined the relationship between respondents' level of prejudicial attitudes and social distance (i.e., stigma) toward individuals who have a mental health condition and their belief in the potential of recovery (2) tested whether previous contact with an individual who received treatment was a mediator. Findings indicated that the belief in recovery led to lower levels of social distance. Prejudicial attitudes were found to be a predictor of one's level of social distance. Previous contact was not a mediator however; males, minorities and those with less education were less likely to have had previous contact. Results indicated a need to emphasize the probability of recovering from a mental health condition when developing target-specific stigma reducing strategies.

  15. The factors in the development of marketing potential of trading enterprises

    Directory of Open Access Journals (Sweden)

    Bubenets Iryna

    2016-03-01

    Full Text Available The purpose of this article is the selection and systematization of the influence factors the formation and development of marketing potential of trading enterprises. Currently, when enterprises have experienced an acute shortage of financial resources the value of the marketing potential of the enterprise increases. Since the marketing potential is determined by the possibility of using their own marketing resources, taking into account external and internal factors, their concretization and systematization for increasing the total effective functioning of the economic subsystems of the enterprise are now becoming ever more relevant. Taking into consideration the content of the main functions of business enterprises the author distinguishes the following groups of factors of formation and development of marketing potential of an enterprise: external (external development resources and market opportunities, external marketing environment; internal (internal marketing environment marketing reflects the tangible and intangible resources and capabilities internal development of commercial enterprise. The author has researched and identified the factors-activators of marketing potential of the trading enterprises, which influence greatly on the current and future state of the management system of the marketing potential of the enterprise and help define the desired strategy for the development of marketing potential.

  16. Possibility and potential of clean development mechanisms in China

    International Nuclear Information System (INIS)

    Gao Weijun; Zhou Nan; Li Haifeng; Kammen, Daniel M

    2007-01-01

    China has become the world's second largest greenhouse gas (GHG) emitter behind the United States. It emits approximately three billion tons of CO 2 equivalents every year. Its growing economy and large population are making a wealthier, more consumption-oriented country. Energy demand is expected to grow 5-10% per year through 2030. Therefore, a large potential of GHG emission reduction in China can be expected. The clean development mechanism (CDM) put forward in the Kyoto Protocol for reductions of GHGs can support the sustainable development of developing countries and help developed countries to achieve their emission reduction targets at low cost. However, there are still many disagreements to be resolved between developing and developed countries. In this letter, we try to introduce the current development of CDM projects in China and discuss its potential and opportunities in the future decades

  17. Cardiovascular magnetic resonance in adults with previous cardiovascular surgery.

    Science.gov (United States)

    von Knobelsdorff-Brenkenhoff, Florian; Trauzeddel, Ralf Felix; Schulz-Menger, Jeanette

    2014-03-01

    Cardiovascular magnetic resonance (CMR) is a versatile non-invasive imaging modality that serves a broad spectrum of indications in clinical cardiology and has proven evidence. Most of the numerous applications are appropriate in patients with previous cardiovascular surgery in the same manner as in non-surgical subjects. However, some specifics have to be considered. This review article is intended to provide information about the application of CMR in adults with previous cardiovascular surgery. In particular, the two main scenarios, i.e. following coronary artery bypass surgery and following heart valve surgery, are highlighted. Furthermore, several pictorial descriptions of other potential indications for CMR after cardiovascular surgery are given.

  18. Development of empirical potentials for amorphous silica

    Energy Technology Data Exchange (ETDEWEB)

    Carre, A.

    2007-09-15

    potential shows a better agreement with the CP data than the BKS ones: pair correlation functions, angular distribution functions, structure factors, density of states and pressure/density were improved. At low temperature, the diffusion coefficients appear to be three times higher than those predicted by the BKS model, however showing a similar temperature dependence. Calculations have also been carried out on crystalline samples in order to check the transferability of the potential. The equilibrium geometry as well as the elastic constants of {alpha}-quartz at 0 K are well described by our new potential although the crystalline phases have not been considered for the parameterization. We have developed a new potential for silica which represents an improvement over the pair potentials class proposed so far. Furthermore, the fitting methodology that has been developed in this work can be applied to other network forming systems such as germania as well as mixtures of SiO{sub 2} with other oxides (e.g. Al{sub 2}O{sub 3}, K{sub 2}O, Na{sub 2}O). (orig.)

  19. Potential of Fishing Port Development in the East Java

    Science.gov (United States)

    Rosana, N.; Prasita, V. D.

    2018-03-01

    The development of fishing ports in East Java is one of efforts to increase the province revenue, develop the fishing industry and to improve the welfare of fishermen. Profile of capture fisheries in East Java should be provide information that can be developed based on priorities and types of resources. The purpose of this study was to determine several districts in East Java which is a priority for the development of fishing ports based on the potential that exists. The method used is descriptive and spatial analysis in order to obtain an overview of the districts in East Java that has the potential to be developed. Results of the study is the districts in East Java are priorities for the development of fishing ports based on aspects related to the fishery is Banyuwangi, Trenggalek and Jember.

  20. Flavonoids from leaves of Derris urucu: assessment of potential effects on seed germination and development of weeds

    Directory of Open Access Journals (Sweden)

    EWERTON A.S. DA SILVA

    2013-09-01

    Full Text Available In some previous studies, we described the isolation of nine compounds from leaves of Derris urucu, a species found widely in the Amazon rainforest, identified as five stilbenes and four dihydroflavonols. In this work, three of these dihydroflavonols [urucuol A (1, urucuol B (2 and isotirumalin (3] were evaluated to identify their potential as allelochemicals, and we are also reporting the isolation and structural determination of a new flavonoid [5,3′-dihydroxy-4′-methoxy-(7,6:5″,6″-2″,2″-dimethylpyranoflavanone (4]. We investigated the effects of the dihydroflavonols 1-3 on seed germination and radicle and hypocotyl growth of the weed Mimosa pudica, using solutions at 150 mg.L–1. Urucuol B, alone, was the substance with the greatest potential to inhibit seed germination (26%, while isotirumalin showed greater ability to reduce the development of the hypocotyl (25%, but none of the three substances showed the potential to inhibit radicle. When combined in pairs, the substances showed synergism for the development of root and hypocotyl and effects on seed germination that could be attributed to antagonism. When tested separately, the trend has become more intense effects on seed germination, while for the substances tested in pairs, the intensity of the effect was greater on development of weed.

  1. Secondary recurrent miscarriage is associated with previous male birth.

    LENUS (Irish Health Repository)

    Ooi, Poh Veh

    2012-01-31

    Secondary recurrent miscarriage (RM) is defined as three or more consecutive pregnancy losses after delivery of a viable infant. Previous reports suggest that a firstborn male child is associated with less favourable subsequent reproductive potential, possibly due to maternal immunisation against male-specific minor histocompatibility antigens. In a retrospective cohort study of 85 cases of secondary RM we aimed to determine if secondary RM was associated with (i) gender of previous child, maternal age, or duration of miscarriage history, and (ii) increased risk of pregnancy complications. Fifty-three women (62.0%; 53\\/85) gave birth to a male child prior to RM compared to 32 (38.0%; 32\\/85) who gave birth to a female child (p=0.002). The majority (91.7%; 78\\/85) had uncomplicated, term deliveries and normal birth weight neonates, with one quarter of the women previously delivered by Caesarean section. All had routine RM investigations and 19.0% (16\\/85) had an abnormal result. Fifty-seven women conceived again and 33.3% (19\\/57) miscarried, but there was no significant difference in failure rates between those with a previous male or female child (13\\/32 vs. 6\\/25, p=0.2). When patients with abnormal results were excluded, or when women with only one previous child were considered, there was still no difference in these rates. A previous male birth may be associated with an increased risk of secondary RM but numbers preclude concluding whether this increases recurrence risk. The suggested association with previous male birth provides a basis for further investigations at a molecular level.

  2. Secondary recurrent miscarriage is associated with previous male birth.

    LENUS (Irish Health Repository)

    Ooi, Poh Veh

    2011-01-01

    Secondary recurrent miscarriage (RM) is defined as three or more consecutive pregnancy losses after delivery of a viable infant. Previous reports suggest that a firstborn male child is associated with less favourable subsequent reproductive potential, possibly due to maternal immunisation against male-specific minor histocompatibility antigens. In a retrospective cohort study of 85 cases of secondary RM we aimed to determine if secondary RM was associated with (i) gender of previous child, maternal age, or duration of miscarriage history, and (ii) increased risk of pregnancy complications. Fifty-three women (62.0%; 53\\/85) gave birth to a male child prior to RM compared to 32 (38.0%; 32\\/85) who gave birth to a female child (p=0.002). The majority (91.7%; 78\\/85) had uncomplicated, term deliveries and normal birth weight neonates, with one quarter of the women previously delivered by Caesarean section. All had routine RM investigations and 19.0% (16\\/85) had an abnormal result. Fifty-seven women conceived again and 33.3% (19\\/57) miscarried, but there was no significant difference in failure rates between those with a previous male or female child (13\\/32 vs. 6\\/25, p=0.2). When patients with abnormal results were excluded, or when women with only one previous child were considered, there was still no difference in these rates. A previous male birth may be associated with an increased risk of secondary RM but numbers preclude concluding whether this increases recurrence risk. The suggested association with previous male birth provides a basis for further investigations at a molecular level.

  3. Junk-food enhances conditioned food cup approach to a previously established food cue, but does not alter cue potentiated feeding; implications for the effects of palatable diets on incentive motivation.

    Science.gov (United States)

    Derman, Rifka C; Ferrario, Carrie R

    2018-03-16

    Efforts to stem the global rise in obesity have been minimally effective, perhaps in part because our understanding of the psychological and behavioral drivers of obesity is limited. It is well established that stimuli that are paired with palatable foods can powerfully influence food-seeking and feeding behaviors. However, how consumption of sugary, fatty "junk-foods" affects these motivational responses to food cues is poorly understood. Here, we determined the effects of short- and long-term "junk-food" consumption on the expression of cue potentiated feeding and conditioned food cup approach to Pavlovian conditioned stimuli (CS). Further, to determine the degree to which effects of "junk-food" were selective to Pavlovian motivational processes, we varied the predictive validity of the CS by including training groups conditioned with unique CS-US contingencies ranging from -1.0 to +1.0. "Junk-food" did not enhance cue potentiated feeding in any group, but expression of this potentiation effect varied with the CS-US contingency independent of diet. In contrast, "junk-food" consistently enhanced conditioned approach to the food cup; this effect was dependent on the previously established CS-US contingency. That is, consumption of "junk-food" following training enhanced approach to the food cup only in response to CSs with previously positive CS-US contingencies. This was accompanied by reduced motivation for the US itself. Together these data show that "junk-food" consumption selectively enhances incentive motivational responses to previously established food CSs, without altering cue potentiated feeding induced by these same CSs, and in the absence of enhanced motivation for food itself. Copyright © 2018 Elsevier Inc. All rights reserved.

  4. Erlotinib-induced rash spares previously irradiated skin

    International Nuclear Information System (INIS)

    Lips, Irene M.; Vonk, Ernest J.A.; Koster, Mariska E.Y.; Houwing, Ronald H.

    2011-01-01

    Erlotinib is an epidermal growth factor receptor inhibitor prescribed to patients with locally advanced or metastasized non-small cell lung carcinoma after failure of at least one earlier chemotherapy treatment. Approximately 75% of the patients treated with erlotinib develop acneiform skin rashes. A patient treated with erlotinib 3 months after finishing concomitant treatment with chemotherapy and radiotherapy for non-small cell lung cancer is presented. Unexpectedly, the part of the skin that had been included in his previously radiotherapy field was completely spared from the erlotinib-induced acneiform skin rash. The exact mechanism of erlotinib-induced rash sparing in previously irradiated skin is unclear. The underlying mechanism of this phenomenon needs to be explored further, because the number of patients being treated with a combination of both therapeutic modalities is increasing. The therapeutic effect of erlotinib in the area of the previously irradiated lesion should be assessed. (orig.)

  5. A potential mate influences reproductive development in female, but not male, pine siskins.

    Science.gov (United States)

    Watts, Heather E; Edley, Bruce; Hahn, Thomas P

    2016-04-01

    The role of photoperiod in avian reproductive timing has been well studied, and we are increasingly recognizing the roles of other environmental cues such as social cues. However, few studies have evaluated the extent to which males and females of the same species respond similarly to the same type of cue. Moreover, previous studies have rarely examined how variation in the quality or nature of a given social cue might modulate its effect. Here, we examine the sensitivity of male and female pine siskins (Spinus pinus) to a potential mate as a stimulatory cue for gonadal recrudescence, and we investigate whether variation in the relationship between a bird and its potential mate modulates the effect of that potential mate. Birds were initially housed without opposite sex birds on a 12L:12D photoperiod with ad libitum food. After gonadal recrudescence had begun males and females were randomly paired with an opposite sex bird or housed alone. An additional group of males was paired with estradiol-implanted females. In males, these social treatments had no effect on testis length, cloacal protuberance length, luteinizing hormone (LH) levels, or testosterone levels. In females, presence of a potential mate had a significant and positive effect on ovary score, defeathering of the brood patch, and LH levels. Among paired birds, the degree of affiliation within a pair corresponded to the extent of reproductive development in females, but not males. Thus, reproductive timing in females appears to be sensitive to both the presence of a potential mate and her relationship with him. Copyright © 2016 Elsevier Inc. All rights reserved.

  6. Potential Predictability of ZPD of Children’s Cognitive Development

    Directory of Open Access Journals (Sweden)

    Parviz Birjandi

    2011-05-01

    Full Text Available Obtaining information on whether the child has the potential for growth is not an easy task. Research shows that using different matrix like Raven or different batteries in a static way cannot
    be indicative of children further development. This study attempts to probe the potential predictability of children’s performance during Dynamic Assessment of their Future development.
    41 children between ages 3 to 6 years old participated in this study. The data in pretest, ZPD, and posttest were converted into Rasch Measure. The results of different analysis indicate that relying on children’s actual performance cannot be an indicative factor of their development in the future.

  7. Retention of high-potential employees in a development finance company

    Directory of Open Access Journals (Sweden)

    Lishani Letchmiah

    2017-09-01

    Full Text Available Orientation: The loss of high-potential employees was a concern to leaders at a South African development finance company. The research question that guided the study was: How can high-potential employees be retained in the company? Research purpose: The objective of the study was to identify factors that positively impact the retention of high-potential employees in a development finance company. Motivation for the study: The organisation that comprised the unit of study had prioritised employee development to retain high-potential employees, thereby aiming to build a strong talent pipeline and a sustainable knowledge base. A prevalent concern was that there were no formal retention programmes for high-potential employees. Accordingly, organisational leaders could benefit from understanding those retention factors that may serve to retain such employees. Research design, approach and method: A qualitative methodology promoted a deeper understanding of a social problem through a case study. Eleven purposefully chosen highpotential employees provided insights into factors they considered to be important in their retention. A content analysis of the data resulted in clusters of themes that addressed the research objective. Main findings: The following factors appeared to influence the retention of high-potential employees: leadership and organisational culture, organisational purpose, developmental opportunities, meaningful work and collegiality. Practical and managerial implications: Leaders in the company should consider factors that could influence the retention of high-potential employees. Such factors should be built into formal retention strategies based on the intrinsic needs of employees; the strengths that the organisational culture provides could be leveraged in this regard. Contribution: The practical value of the study was the highlighting of the factors that can be leveraged to retain high-potential employees in a development finance

  8. Potentials Of Agro-Tourism For Rural Development In Nigeria ...

    African Journals Online (AJOL)

    This paper highlights the potentials of agro-tourism for rural development in Nigeria and made policy recommendations for agro-tourism to flourish. The potentials include the promotion of entrepreneurship and industrialization, economic advancement, education and good health of the citizen. It was recommended that for ...

  9. Classification of geothermal resources by potential

    Science.gov (United States)

    Rybach, L.

    2015-03-01

    When considering and reporting resources, the term "geothermal potential" is often used without clearly stating what kind of potential is meant. For renewable energy resources it is nowadays common to use different potentials: theoretical, technical, economic, sustainable, developable - decreasing successively in size. In such a sequence, the potentials are progressively realizable and more and more rewarding financially. The theoretical potential describes the physically present energy, the technical potential the fraction of this energy that can be used by currently available technology and the economic potential the time- and location-dependent fraction of the previous category; the sustainable potential constrains the fraction of the economic potential that can be utilized in the long term; the developable potential is the fraction of the economic resource which can be developed under realistic conditions. In converting theoretical to technical potential, the recovery factor (the ratio extractable heat/heat present at depth) is of key importance. An example (global geothermal resources) is given, with numerical values of the various potentials. The proposed classification could and should be used as a kind of general template for future geothermal energy resources reporting.

  10. Conceptual aspects: analyses law, ethical, human, technical, social factors of development ICT, e-learning and intercultural development in different countries setting out the previous new theoretical model and preliminary findings

    NARCIS (Netherlands)

    Kommers, Petrus A.M.; Smyrnova-Trybulska, Eugenia; Morze, Natalia; Issa, Tomayess; Issa, Theodora

    2015-01-01

    This paper, prepared by an international team of authors focuses on the conceptual aspects: analyses law, ethical, human, technical, social factors of ICT development, e-learning and intercultural development in different countries, setting out the previous and new theoretical model and preliminary

  11. African Initiated Churches’ potential as development actors

    Directory of Open Access Journals (Sweden)

    Philipp Öhlmann

    2016-11-01

    Full Text Available African Initiated Churches (AICs are not yet recognised as relevant actors of community development interventions. While it has been acknowledged that many of them provide coping mechanisms in adverse environments, support in social transformation and social capital, little information is available on their role as development actors. In this article, we evaluate the potential of AICs as partners of international development agencies for community development. We draw on interviews and focus group discussions with leaders of various AICs conducted in South Africa in February and March 2016. In particular, we examine the churches’ understanding of development, their view on the separation of spiritual and development activities and their priorities. Moreover, we outline the development activities which they are currently engaged in and analyse the structures they have in place to do so. Our findings indicate that AICs are increasingly active in community development and offer various entry points for possible cooperation.

  12. Global wind power potential: Physical and technological limits

    International Nuclear Information System (INIS)

    Castro, Carlos de; Mediavilla, Margarita; Miguel, Luis Javier; Frechoso, Fernando

    2011-01-01

    This paper is focused on a new methodology for the global assessment of wind power potential. Most of the previous works on the global assessment of the technological potential of wind power have used bottom-up methodologies (e.g. ). Economic, ecological and other assessments have been developed, based on these technological capacities. However, this paper tries to show that the reported regional and global technological potential are flawed because they do not conserve the energetic balance on Earth, violating the first principle of energy conservation (). We propose a top-down approach, such as that in , to evaluate the physical-geographical potential and, for the first time, to evaluate the global technological wind power potential, while acknowledging energy conservation. The results give roughly 1 TW for the top limit of the future electrical potential of wind energy. This value is much lower than previous estimates and even lower than economic and realizable potentials published for the mid-century (e.g. ). - Highlights: → Reported wind power potentials are flawed because they violate energy conservation. → For the first time, it is evaluated the technological wind power potential with a top-down approach. → Our results show 1 TWe for the limit of wind power energy, which is much lower than previous estimates.

  13. On the Tengiz petroleum deposit previous study

    International Nuclear Information System (INIS)

    Nysangaliev, A.N.; Kuspangaliev, T.K.

    1997-01-01

    Tengiz petroleum deposit previous study is described. Some consideration about structure of productive formation, specific characteristic properties of petroleum-bearing collectors are presented. Recommendation on their detail study and using of experience on exploration and development of petroleum deposit which have analogy on most important geological and industrial parameters are given. (author)

  14. Energy development potential: An analysis of Brazil

    International Nuclear Information System (INIS)

    Perobelli, Fernando Salgueiro; Oliveira, Caio Cézar Calheiros de

    2013-01-01

    This paper develops an indicator for the energy development potential (EDP) of 27 Brazilian states. This indicator uses data on a state's infrastructure and its supply of and demand for energy. The indicator measures the data for three periods: the first part of the 1990s, which is a period of low economic growth; the first part of the 2000s, which is a period of high economic growth but with a historical crisis in the Brazilian energy sector; and 2009–2011, which is a period of economic growth after the energy crisis. Using a factor analysis, we are able to identify three factors for EDP. They are the demand for energy, the supply of renewable energy, and the supply of nonrenewable energy. We use these factors to classify the Brazilian states according to their EDP and to perform an exploratory spatial data analysis (ESDA) by using the Moran indicators and the local indicators of spatial association (LISA). - Highlights: • This paper deals with the spatial dimension of the Brazilian energy sector. • We construct an index of the energy development potential for Brazilian states. • Energy issues are defined over time and space, thus have spatial dimensions. • The spatial results show that there are two well-defined spatial patterns

  15. Potential contribution of biomass to the sustainable energy development

    International Nuclear Information System (INIS)

    Demirbas, M. Fatih; Balat, Mustafa; Balat, Havva

    2009-01-01

    Biomass is a renewable energy source and its importance will increase as national energy policy and strategy focuses more heavily on renewable sources and conservation. Biomass is considered the renewable energy source with the highest potential to contribute to the energy needs of modern society for both the industrialized and developing countries worldwide. The most important biomass energy sources are wood and wood wastes, agricultural crops and their waste byproducts, municipal solid waste, animal wastes, waste from food processing, and aquatic plants and algae. Biomass is one potential source of renewable energy and the conversion of plant material into a suitable form of energy, usually electricity or as a fuel for an internal combustion engine, can be achieved using a number of different routes, each with specific pros and cons. Currently, much research has been focused on sustainable and environmental friendly energy from biomass to replace conventional fossil fuels. The main objective of the present study is to investigate global potential and use of biomass energy and its contribution to the sustainable energy development by presenting its historical development.

  16. Commentary: The Development of Creativity--Ability, Motivation, and Potential

    Science.gov (United States)

    Silvia, Paul J.; Christensen, Alexander P.; Cotter, Katherine N.

    2016-01-01

    A major question for research on the development of creativity is whether it is interested in "creative potential" (a prospective approach that uses measures early in life to predict adult creativity) or in children's creativity for its own sake. We suggest that a focus on potential for future creativity diminishes the fascinating…

  17. Subsequent childbirth after a previous traumatic birth.

    Science.gov (United States)

    Beck, Cheryl Tatano; Watson, Sue

    2010-01-01

    Nine percent of new mothers in the United States who participated in the Listening to Mothers II Postpartum Survey screened positive for meeting the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition criteria for posttraumatic stress disorder after childbirth. Women who have had a traumatic birth experience report fewer subsequent children and a longer length of time before their second baby. Childbirth-related posttraumatic stress disorder impacts couples' physical relationship, communication, conflict, emotions, and bonding with their children. The purpose of this study was to describe the meaning of women's experiences of a subsequent childbirth after a previous traumatic birth. Phenomenology was the research design used. An international sample of 35 women participated in this Internet study. Women were asked, "Please describe in as much detail as you can remember your subsequent pregnancy, labor, and delivery following your previous traumatic birth." Colaizzi's phenomenological data analysis approach was used to analyze the stories of the 35 women. Data analysis yielded four themes: (a) riding the turbulent wave of panic during pregnancy; (b) strategizing: attempts to reclaim their body and complete the journey to motherhood; (c) bringing reverence to the birthing process and empowering women; and (d) still elusive: the longed-for healing birth experience. Subsequent childbirth after a previous birth trauma has the potential to either heal or retraumatize women. During pregnancy, women need permission and encouragement to grieve their prior traumatic births to help remove the burden of their invisible pain.

  18. China: an emerging offshore wind development hotspot. With a new assessment of China's offshore wind potential

    Energy Technology Data Exchange (ETDEWEB)

    Reinvang, Rasmus; Enslow, Rachel; Beaumont, Hubert

    2010-08-15

    This study provides new and more detailed estimates of the offshore wind energy resources in China, with particular focus on Southern China. The study points out that the offshore wind industry is ramping up in China with at least 11.9GW in the development pipeline per April 2010. The study estimates the offshore wind potential of China (excluding Taiwan) to 11,580TWh/year. The study proves estimates and wind energy resource maps per province. Fujian, Zhejiang and Hainan stand out with the highest offshore wind speeds in China while Guangdong also shows significant potential, with annual wind speed averages of 6.5-10.2m/s and an energy density range of 12-36GWh/km2. Even though current offshore wind development is mainly taking place in Fujian and Jiangsu, this study shows that the potential is likely even greater in other provinces. The study was developed by the Chinese Wind Energy Association (CWEA) and Sun Yat-sen University, and commissioned by WWF as part of a project funded by the Norwegian Agency of development Coopeartion (Norad). Methodology and constraints: The wind resource analysis improves upon previous studies in estimating the wind energy generation potential for offshore wind power in China, with available meteorological data adjusted for influence of typhoons. The study models how much energy offshore wind can produce along China's coast up to 100km from the shore by calculating the energy output of theoretical wind farms by applying the power curve of a 3MW turbine at a 100m hub height. In addition the study further expands by giving special consideration to the deep-sea offshore potential at +50m water depths. The study focuses particularly on the coastline from Shandong down to Hainan. The final results provide good indication of the offshore wind resource in China when comparing one area to the other. The report can therefore be used as a preliminary tool to identifying most interesting provinces and locations for offshore wind

  19. Development of technique for diagnostics of social reserves of development of collective labour potential

    OpenAIRE

    Голубєв, Станіслав Миколайович

    2015-01-01

    The problems of diagnostics of social reserves of the collective labour potential are considered in the article. The aim of this study is to develop diagnostic techniques of social reserves of the collective labour potential in the work and the essence of the concept of "social reserves" as a subject of study of economics and their features in the study of collective labour potential. The use of these reserves can increase the efficiency of the labour collective processes by improving coopera...

  20. Dietary self-efficacy predicts AHEI diet quality in women with previous gestational diabetes.

    Science.gov (United States)

    Ferranti, Erin Poe; Narayan, K M Venkat; Reilly, Carolyn M; Foster, Jennifer; McCullough, Marjorie; Ziegler, Thomas R; Guo, Ying; Dunbar, Sandra B

    2014-01-01

    The purpose of this study was to examine the association of intrapersonal influences of diet quality as defined by the Health Belief Model constructs in women with recent histories of gestational diabetes. A descriptive, correlational, cross-sectional design was used to analyze relationships between diet quality and intrapersonal variables, including perceptions of threat of type 2 diabetes mellitus development, benefits and barriers of healthy eating, and dietary self-efficacy, in a convenience sample of 75 community-dwelling women (55% minority; mean age, 35.5 years; SD, 5.5 years) with previous gestational diabetes mellitus. Diet quality was defined by the Alternative Healthy Eating Index (AHEI). Multiple regression was used to identify predictors of AHEI diet quality. Women had moderate AHEI diet quality (mean score, 47.6; SD, 14.3). Only higher levels of education and self-efficacy significantly predicted better AHEI diet quality, controlling for other contributing variables. There is a significant opportunity to improve diet quality in women with previous gestational diabetes mellitus. Improving self-efficacy may be an important component to include in nutrition interventions. In addition to identifying other important individual components, future studies of diet quality in women with previous gestational diabetes mellitus are needed to investigate the scope of influence beyond the individual to potential family, social, and environmental factors. © 2014 The Author(s).

  1. Potentials of Local Economic Development in Aspect of Tourism

    Directory of Open Access Journals (Sweden)

    Viktória Csizmadiáné Czuppon

    2015-10-01

    Full Text Available The objective of the study is to introduce the potentials of local economic development in one of the least favoured micro regions, Tamási. The paper examines operating and planned activities at settlements of the micro region. The authors introduce local economic development activities that support tourism. The economic development planning in Tamási micro region has typically two directions. One of them is the utilisation of thermal water and the use of further potentials of the thermal bath (Ability, such as to achieve tourism destination function in Hungary. Secondly, the local government aims to sell its fruits and vegetables produced in the frame of public employment programme for local market and institutions. The supply of local population has got in focus because of current external opportunities (or force? in the settlements being traditionally agricultural area. The objective is to join the local tourism attractions and destinations with other existing local developments, which is hold back by the owners of developments. The authors – by keeping in mind local conditions and endogenous resources – define recommendations for settlements to be able to create a well-organised framework of local economic development.

  2. The formation and development of innovative potential of the company’s employees

    Directory of Open Access Journals (Sweden)

    E. A. Kipervar

    2016-01-01

    Full Text Available Modern economic development is possible on the basis of increase of efficiency of activity of enterprises, which is based on the rational use of the labor potential of employees. The current research is formulated and enriched the concept of labor potential, but there are still many unresolved theoretical and methodologically aspects related to the study of labor potential and its components, as they arise in connection with changes in the economy, the modern requirements to enterprises in the period of their innovative development. Innovative activities of enterprises should be based on the use of highly skilled, highly intelligent, high-performance staff able to generate, develop, apply new ideas, technologies and products. The requirements of the environment to stimulate enterprise in the formation of personnel, concerned in the results of the enterprise, upbeat and generating innovation. Particular attention should be given to the formation and development of innovative potential of employees as part of the labor potential, its planning, that will be reflected in improving the efficiency of the personnel and the efficiency of enterprises. It is necessary to further develop approaches to the formation and development of the capacity of workers in relation to the innovation component of labor potential, aimed at improving the competitiveness of enterprises. Results of the research outlined in this paper are aimed at deepening and broadening of theoretical bases in this area. The authors of the necessity of innovative development based on employee motivation structure and the level of their claims, professional, intellectual level, as well as realize their innovative potential. The necessity of its correction and give you strength-of planning in the direction of determining acceptable and normative values of the innovative potential of each category of workers, determination of deviations of actual values from the standard followed by the

  3. Prevalent musculoskeletal pain as a correlate of previous exposure to torture

    DEFF Research Database (Denmark)

    Olsen, Dorte Reff; Montgomery, Edith; Bojholm, S

    2006-01-01

    AIM: To research possible associations between previous exposure to specific torture techniques and prevalent pain in the head and face, back, and feet. METHODS: 221 refugees, 193 males and 28 females, previously exposed to torture in their home country, were subject to a clinical interview...... was general abuse of the whole body (OR 5.64, 95% CI 1.93-16.45). CONCLUSION: In spite of many factors being potentially co-responsible for prevalent pain, years after the torture took place it presents itself as strongly associated with specific loci of pain, with generalized effects, and with somatizing....

  4. Estimation of potential uranium resources

    International Nuclear Information System (INIS)

    Curry, D.L.

    1977-09-01

    Potential estimates, like reserves, are limited by the information on hand at the time and are not intended to indicate the ultimate resources. Potential estimates are based on geologic judgement, so their reliability is dependent on the quality and extent of geologic knowledge. Reliability differs for each of the three potential resource classes. It is greatest for probable potential resources because of the greater knowledge base resulting from the advanced stage of exploration and development in established producing districts where most of the resources in this class are located. Reliability is least for speculative potential resources because no significant deposits are known, and favorability is inferred from limited geologic data. Estimates of potential resources are revised as new geologic concepts are postulated, as new types of uranium ore bodies are discovered, and as improved geophysical and geochemical techniques are developed and applied. Advances in technology that permit the exploitation of deep or low-grade deposits, or the processing of ores of previously uneconomic metallurgical types, also will affect the estimates

  5. The mountain Cer: Potentials for tourism development

    Directory of Open Access Journals (Sweden)

    Grčić Mirko D.

    2003-01-01

    Full Text Available In northwest of Serbia in the meridians directions an elongated mountain range of Cer with Iverak and Vlašić stretches itself. On the north it goes down to Mačva and Posavina, on the west to Podrinje, on the east to the valley of Kolubara, on the south to the basins and valleys of Jadar and upper Kolubara, which separate it from the mountains of Valjevo and Podrinje area. Cer mountain offers extremely good condition for development of eco-tourism. The variety of relief with gorgeous see-sites, natural rarities, convenient bio-climatic conditions, significant water resources, forest complexes, medieval fortresses, cultural-historic monuments, richness of flora and fauna, preserved rural environment, traditions and customs of local population, were all neglected as strategic factors in the development of tourism. This mountain’s potentials are quite satisfactory for the needs of eco-tourism, similar to the National Park of Fruška Gora, but it has lacked an adequate ecotourist strategy so far. This study aims to pointing to the potential and possibilities of ecotourist valorization of this mountain.

  6. Estimation of un-used land potential for biofuels development in China

    Energy Technology Data Exchange (ETDEWEB)

    Tian, Yishui [Chinese Academy of Agricultural Engineering, Beijing 100026 (China); Maelardalen University, Vaesteraas SE-721 23 (Sweden); Zhao, Lixin; Meng, Haibo; Sun, Liying [Chinese Academy of Agricultural Engineering, Beijing 100026 (China); Yan, Jinyue [Maelardalen University, Vaesteraas SE-721 23 (Sweden); Royal Institute of Technology, SE-100 44 Stockholm (Sweden)

    2009-11-15

    This paper presents the current status of biofuel development and estimates the potential of un-used land for biofuel development. The potential of crops including cassava, sweet potato, sweet sorghum, sugarcane, sugar beet and Jerusalem artichoke were assessed and discussed for different regions considering the geographical conditions and features of agricultural production. If reserved land resources are explored together with substitute planting implemented and unit area yield improved, potential production of ethanol fuel will be 22 million ton in 2020. The study also recommends the use of winter idle lands for rapeseed plantation for biofuel production. The potential for production of biodiesel by rapeseed and cottonseed can reach to 3.59 million ton. (author)

  7. Development of the human potential in Russian and foreign countries

    Directory of Open Access Journals (Sweden)

    Mikhail Ivanovich Maslennikov

    2013-09-01

    Full Text Available In the article, theoretical and methodical approaches to human development in Russia and foreign countries are analyzed. The contribution of the various countries to its formation and development is revealed. The indicators showing a level of development of human potential and components forming it in the creation of gross domestic product are analyzed. The alternative options of development of education, health care and science, expenses and benefit from their commercialization are revealed. The role of the state, federal regions and local authorities in management and development of health care, education, science during periods of crises, depressions and increases of economic activity is investigated. The interrelation of levels of development of the economy and human potential, with the levels and the population living conditions are revealed. The reasons of close attention of the governments of the developed countries to human development, and also the measures undertaken on minimization of interregional disproportions in its development become clear. Mechanisms and tools of development of health care, education, science in various regions of the world, a way of use of transfers, subsidies and grants on their development are investigated

  8. Potential distribution of dengue fever under scenarios of climate change and economic development.

    Science.gov (United States)

    Aström, Christofer; Rocklöv, Joacim; Hales, Simon; Béguin, Andreas; Louis, Valerie; Sauerborn, Rainer

    2012-12-01

    Dengue fever is the most important viral vector-borne disease with ~50 million cases per year globally. Previous estimates of the potential effect of global climate change on the distribution of vector-borne disease have not incorporated the effect of socioeconomic factors, which may have biased the results. We describe an empirical model of the current geographic distribution of dengue, based on the independent effects of climate and gross domestic product per capita (GDPpc, a proxy for socioeconomic development). We use the model, along with scenario-based projections of future climate, economic development, and population, to estimate populations at risk of dengue in the year 2050. We find that both climate and GDPpc influence the distribution of dengue. If the global climate changes as projected but GDPpc remained constant, the population at risk of dengue is estimated to increase by about 0.28 billion in 2050. However, if both climate and GDPpc change as projected, we estimate a decrease of 0.12 billion in the population at risk of dengue in 2050. Empirically, the geographic distribution of dengue is strongly dependent on both climatic and socioeconomic variables. Under a scenario of constant GDPpc, global climate change results in a modest but important increase in the global population at risk of dengue. Under scenarios of high GDPpc, this adverse effect of climate change is counteracted by the beneficial effect of socioeconomic development.

  9. 24 CFR 1710.552 - Previously accepted state filings.

    Science.gov (United States)

    2010-04-01

    ... of Substantially Equivalent State Law § 1710.552 Previously accepted state filings. (a) Materials... and contracts or agreements contain notice of purchaser's revocation rights. In addition see § 1715.15..., unless the developer is obligated to do so in the contract. (b) If any such filing becomes inactive or...

  10. [Fatal amnioinfusion with previous choriocarcinoma in a parturient woman].

    Science.gov (United States)

    Hrgović, Z; Bukovic, D; Mrcela, M; Hrgović, I; Siebzehnrübl, E; Karelovic, D

    2004-04-01

    The case of 36-year-old tercipare is described who developed choriocharcinoma in a previous pregnancy. During the first term labour the patient developed cardiac arrest, so reanimation and sectio cesarea was performed. A male new-born was delivered in good condition, but even after intensive therapy and reanimation occurred death of parturient woman with picture of disseminate intravascular coagulopathia (DIK). On autopsy and on histology there was no sign of malignant disease, so it was not possible to connect previous choricarcinoma with amniotic fluid embolism. Maybe was place of choriocarcinoma "locus minoris resistentiae" which later resulted with failure in placentation what was hard to prove. On autopsy we found embolia of lung with a microthrombosis of terminal circulation with punctiformis bleeding in mucous, what stands for DIK.

  11. The Potential for Renewable Energy Development to Benefit Restoration of the Salton Sea. Analysis of Technical and Market Potential

    Energy Technology Data Exchange (ETDEWEB)

    Gagne, Douglas [National Renewable Energy Lab. (NREL), Golden, CO (United States); Haase, Scott [National Renewable Energy Lab. (NREL), Golden, CO (United States); Oakleaf, Brett [National Renewable Energy Lab. (NREL), Golden, CO (United States); Hurlbut, David [National Renewable Energy Lab. (NREL), Golden, CO (United States); Akar, Sertac [National Renewable Energy Lab. (NREL), Golden, CO (United States); Wall, Anna [National Renewable Energy Lab. (NREL), Golden, CO (United States); Turchi, Craig [National Renewable Energy Lab. (NREL), Golden, CO (United States); Pienkos, Philip [National Renewable Energy Lab. (NREL), Golden, CO (United States); Melius, Jennifer [National Renewable Energy Lab. (NREL), Golden, CO (United States); Melaina, Marc [National Renewable Energy Lab. (NREL), Golden, CO (United States)

    2015-11-01

    This report summarizes the potential for renewable energy development in the Salton Sea region, as well as the potential for revenues from this development to contribute financially to Salton Sea restoration costs. It considers solar, geothermal, biofuels or nutraceutical production from algae pond cultivation, desalination using renewable energy, and mineral recovery from geothermal fluids.


  12. Development of an interatomic EAM type potential for Zr

    International Nuclear Information System (INIS)

    Pasianot, R.C.; Monti, A.M.

    1996-01-01

    In the present work are developed interatomic potentials of the embedded atom type (EAM) adequate for computer simulation of microstructural defects in the Zr lattice. It is observed that the less repulsive potential agrees better with the experimental data of the self-interstitial relaxation volume and predicts the basal crowdion as the stable configuration, the basal dumbbell having a formation energy slightly higher (0.01 eV). (author). 9 refs., 1 fig., 3 tabs

  13. GPS-Based AR Games Development Potential

    Directory of Open Access Journals (Sweden)

    Gregorius Alvin Raditya Santoso

    2014-11-01

    Full Text Available The application of new technologies in a game is not a new thing. One example is the application of Augmented Reality (AR technology in game. Many people do not know the application of AR technology in game, although the application of this technology is able to produce a game with unique gameplay. In addition, since AR game is GPS-based, it offers new gaming experience, that is, playing outdoors in which the real world becomes the game arena. This advantage gives the AR technology a huge potential to be developed into a game

  14. Potentiality Prediction of Electric Power Replacement Based on Power Market Development Strategy

    Science.gov (United States)

    Miao, Bo; Yang, Shuo; Liu, Qiang; Lin, Jingyi; Zhao, Le; Liu, Chang; Li, Bin

    2017-05-01

    The application of electric power replacement plays an important role in promoting the development of energy conservation and emission reduction in our country. To exploit the potentiality of regional electric power replacement, the regional GDP (gross domestic product) and energy consumption are taken as potentiality evaluation indicators. The principal component factors are extracted with PCA (principal component analysis), and the integral potentiality analysis is made to the potentiality of electric power replacement in the national various regions; a region is taken as a research object, and the potentiality of electric power replacement is defined and quantified. The analytical model for the potentiality of multi-scenario electric power replacement is developed, and prediction is made to the energy consumption with the grey prediction model. The relevant theoretical research is utilized to realize prediction analysis on the potentiality amount of multi-scenario electric power replacement.

  15. Radon baseline monitoring around a potential shale gas development site in Yorkshire, England

    International Nuclear Information System (INIS)

    Daraktchieva, Z.; Wasikiewicz, J. M.; Howarth, C. B.; Bradley, E.J.

    2017-01-01

    The Vale of Pickering in Yorkshire, England has been identified as a potential area for shale gas extraction. Public Health England joined a collaboration led by the British Geological Survey for environmental baseline monitoring near the potential shale gas extraction site following a grant award from UK Government Department for Business, Energy and Industrial Strategy. The analysis of results for the first 6 months of indoor monitoring indicated that the results followed a log-normal distribution. The numbers of homes found to be at or above the Action Level followed the numbers predicted by the radon potential maps. The results from the measurements of outdoor air in this study indicated that the radon concentrations are slightly higher than previously measured but close to the detection limit of the technique. (authors)

  16. Mineral development prospects of the Indochina area: Potential exceeds problems

    Energy Technology Data Exchange (ETDEWEB)

    Clark, A L; Dorian, J P; Hudders, W A [East-West Center, Honolulu, HI (United States)

    1991-02-01

    Reform is under way in several nations within the Indochina area to stimulate economic growth and foreign investment. Though once forbidden, participation by foreign companies in mining exploration and development activities in Myanmar, Kampuchea, Laos, Thailand and Vietnam is now being solicited by the respective governments. This paper presents a preliminary evaluation of mineral and energy resources in the region and outlines possible development scenarios based on economic policies, financial and infrastructural constraints and industry interest. The investment climates for resource-related projects are assessed qualitatively by country. Clearly, the long-term development potential of mineral and energy resources in the Indochina area is large, and the potential gains outweigh any of today's problems. (author). 34 refs, 1 fig., 12 tabs.

  17. Agronomic potentials of quality protein maize hybrids developed in ...

    African Journals Online (AJOL)

    Agronomic potentials of quality protein maize hybrids developed in Ghana. ... Ghana Journal of Agricultural Science ... and Wheat Improvement (CIMMYT) were evaluated on research stations and in farmers\\' fields in Ghana from 1995 to 1996.

  18. The Boom of Electricity Demand in the Residential Sector in the Developing World and the Potential for Energy Efficiency

    Energy Technology Data Exchange (ETDEWEB)

    Letschert, Virginie; McNeil, Michael A.

    2008-05-13

    With the emergence of China as the world's largest energy consumer, the awareness of developing country energy consumption has risen. According to common economic scenarios, the rest of the developing world will probably see an economic expansion as well. With this growth will surely come continued rapid growth in energy demand. This paper explores the dynamics of that demand growth for electricity in the residential sector and the realistic potential for coping with it through efficiency. In 2000, only 66% of developing world households had access to electricity. Appliance ownership rates remain low, but with better access to electricity and a higher income one can expect that households will see their electricity consumption rise significantly. This paper forecasts developing country appliance growth using econometric modeling. Products considered explicitly - refrigerators, air conditioners, lighting, washing machines, fans, televisions, stand-by power, water heating and space heating - represent the bulk of household electricity consumption in developing countries. The resulting diffusion model determines the trend and dynamics of demand growth at a level of detail not accessible by models of a more aggregate nature. In addition, the paper presents scenarios for reducing residential consumption through cost-effective and/or best practice efficiency measures defined at the product level. The research takes advantage of an analytical framework developed by LBNL (BUENAS) which integrates end use technology parameters into demand forecasting and stock accounting to produce detailed efficiency scenarios, which allows for a realistic assessment of efficiency opportunities at the national or regional level. The past decades have seen some of the developing world moving towards a standard of living previously reserved for industrialized countries. Rapid economic development, combined with large populations has led to first China and now India to emerging as &apos

  19. HUMAN POTENTIAL AS A SOURCE OF ECONOMICAL DEVELOPMENT IN BEIUŞ LAND

    Directory of Open Access Journals (Sweden)

    Claudiu FILIMON

    2013-12-01

    Full Text Available : The present study that focuses on the human potential in Beiuş Land, seen as a source of economical development, aims at highlighting the human resource existing in this area. It constitutes the engine or the dynamic element of the economical development. Such an endeavour is necesssary and needs accomplishment, in order to support some territorial development policies, regardless of the scale they are set on. Its analysis of Beiuş Land highlighted the existence of several drawbacks of the human potential, triggered by the demographic aging process, but also by the possibilities this area offers. Depending on its evolution, it is necessary to achieve a certain level of development which should ensure its welfare status.

  20. Iodine-131 induced hepatotoxicity in previously healthy patients with Grave's disease.

    Science.gov (United States)

    Jhummon, Navina Priya; Tohooloo, Bhavna; Qu, Shen

    2013-01-01

    To describe the association of the rare and serious complication of liver toxicity in previously healthy Grave's disease (GD) patients after the treatment with radioactive iodine (131)I (RAI). We report the clinical, laboratory and pathologic findings of 2 cases of severe liver toxicity associated with the treatment with RAI in previously healthy patients with GD. Clinical examination and laboratory investigations excluded viral hepatitis, autoimmune hepatitis, granulomatous disease, primary biliary disease, extrahepatic biliary obstruction, and heart failure. Case 1: A previously healthy 52-years old man reportedly having a typical GD but following RAI treatment, concomitantly developed severe liver toxicity that required 1 week of treatment in hospital. Case 2: A previously healthy 34-years old woman is reported as having a typical GD but developed jaundice following RAI treatment that required several weeks of in hospital treatment in the hepato-biliary department. In both cases, the liver dysfunction resolved after intensive treatment with hepato-protective agents. In this report the therapeutic considerations as well as the pathogenetic possibilities are reviewed. To the best of our knowledge, this is the first description of the association observed, which is rare but may be severe and should be considered in any case of thyrotoxicosis where a liver dysfunction develops after the treatment with radioactive iodine (131)I.

  1. Interpreting "Personality" Taxonomies: Why Previous Models Cannot Capture Individual-Specific Experiencing, Behaviour, Functioning and Development. Major Taxonomic Tasks Still Lay Ahead.

    Science.gov (United States)

    Uher, Jana

    2015-12-01

    As science seeks to make generalisations, a science of individual peculiarities encounters intricate challenges. This article explores these challenges by applying the Transdisciplinary Philosophy-of-Science Paradigm for Research on Individuals (TPS-Paradigm) and by exploring taxonomic "personality" research as an example. Analyses of researchers' interpretations of the taxonomic "personality" models, constructs and data that have been generated in the field reveal widespread erroneous assumptions about the abilities of previous methodologies to appropriately represent individual-specificity in the targeted phenomena. These assumptions, rooted in everyday thinking, fail to consider that individual-specificity and others' minds cannot be directly perceived, that abstract descriptions cannot serve as causal explanations, that between-individual structures cannot be isomorphic to within-individual structures, and that knowledge of compositional structures cannot explain the process structures of their functioning and development. These erroneous assumptions and serious methodological deficiencies in widely used standardised questionnaires have effectively prevented psychologists from establishing taxonomies that can comprehensively model individual-specificity in most of the kinds of phenomena explored as "personality", especially in experiencing and behaviour and in individuals' functioning and development. Contrary to previous assumptions, it is not universal models but rather different kinds of taxonomic models that are required for each of the different kinds of phenomena, variations and structures that are commonly conceived of as "personality". Consequently, to comprehensively explore individual-specificity, researchers have to apply a portfolio of complementary methodologies and develop different kinds of taxonomies, most of which have yet to be developed. Closing, the article derives some meta-desiderata for future research on individuals' "personality".

  2. On the Lienard-Wiechert potentials

    International Nuclear Information System (INIS)

    Whitney, C.K.

    1988-01-01

    Very recently, questions have started to surface concerning the well-known Lienard-Wiechert potentials describing relativistically moving point sources in classical electrodynamics. The existence of questions prompts a review of the original derivations by Lienard and Wiechert. These were done at the turn of the present century, and so predate the development of relevant modern techniques from special relativity theory and generalized function theory. Only purely geometric reasoning was used. That reasoning is reviewed here, and a previously unrecognized flaw is noted. When this flaw is remedied, the potentials are slightly altered and become consistent with other new results reported elsewhere

  3. Reasoning with Previous Decisions: Beyond the Doctrine of Precedent

    DEFF Research Database (Denmark)

    Komárek, Jan

    2013-01-01

    in different jurisdictions use previous judicial decisions in their argument, we need to move beyond the concept of precedent to a wider notion, which would embrace practices and theories in legal systems outside the Common law tradition. This article presents the concept of ‘reasoning with previous decisions...... law method’, but they are no less rational and intellectually sophisticated. The reason for the rather conceited attitude of some comparatists is in the dominance of the common law paradigm of precedent and the accompanying ‘case law method’. If we want to understand how courts and lawyers......’ as such an alternative and develops its basic models. The article first points out several shortcomings inherent in limiting the inquiry into reasoning with previous decisions by the common law paradigm (1). On the basis of numerous examples provided in section (1), I will present two basic models of reasoning...

  4. Potential Trade-Offs between the Sustainable Development Goals in Coastal Bangladesh

    Directory of Open Access Journals (Sweden)

    Craig W. Hutton

    2018-04-01

    Full Text Available The Sustainable Development Goals (SDGs are offered as a comprehensive strategy to guide and encourage sustainable development at multiple scales both nationally and internationally. Furthermore, through the development of indicators associated with each goal and sub-goal, the SDGs support the notion of monitoring, evaluation and adaptive management, underpinned by the aspirations of social justice, equity and transparency. As such, the ethical intention of the SDGs is well founded. However, possible conflicts and trade-offs between individual SDGs have received little attention. For example, SDGs relating to poverty (SDG 1, inequality (SDG 10, food security (SDG2, economic development (SDG 8 and life in water and on land (SDGs 14 and 15, are potentially competing in many circumstances. In a social–ecological context, policy support and formulation are increasingly adopting systems approaches, which analyse the complex interactions of system elements. Adopting such an approach in this work, the above SDGs are analysed for coastal Bangladesh. This demonstrates multiple potential trade-offs between the SDGs, including agricultural farming approaches in the light of poverty reduction, and between economic growth and environmental integrity as well as equity. To develop coherent and policy relevant socio-ecological strategies, appropriate decision frameworks need to be co-developed across the range of stakeholders and decision-makers. Integrated models have great potential to support such a process.

  5. Previous Exposure to the Fish Parasite Anisakis as a Potential Risk Factor for Gastric or Colon Adenocarcinoma.

    Science.gov (United States)

    Garcia-Perez, Juan Carlos; Rodríguez-Perez, Rosa; Ballestero, Araceli; Zuloaga, Jaime; Fernandez-Puntero, Belen; Arias-Díaz, Javier; Caballero, María Luisa

    2015-10-01

    Anisakiasis is a global disease caused by consumption of raw or lightly cooked fish contaminated with L3 Anisakis spp. larvae. High rates of parasitization of fish worldwide make Anisakis a serious health hazard. In fact, anisakiasis is a growing disease in countries such as Spain, Italy, and Japan, where consumption of raw/marinated fish is high. Some parasitic infections have been recognized as a causative factor for human cancer. Suggested mechanisms include chronic inflammation elicited by the parasite, and a possible tumorigenic effect from certain parasitic secretions. Anisakis can produce persistent local inflammation and granuloma, and larvae have been incidentally found in gastrointestinal (GI) tumors. Our aim was to discover possible differences in the prevalence of unnoticed or asymptomatic previous Anisakis infection in GI cancer patients compared with healthy individuals. Serum levels of specific antibodies against Anisakis antigens were used as a reliable marker of previous contact with their larvae. Ninety-four participants without a previous history of Anisakis infection were prospectively allocated into 1 of 2 groups: 47 patients with GI cancer and 47 controls. Specific IgE, IgA1, and IgG1 against the Anisakis recombinant antigens Ani s 1, Ani s 5, Ani s 9, and Ani s 10 were determined by an ELISA assay. The ratio of positivity to sIgA1, rAni s 1, or rAni s 5 was significantly higher in the cancer patients than in the controls (38.30% vs 6.38%, P cancer showed a higher proportion of positive results for sIgA1 to rAni s 1 (P cancer patients were shown to be positive for sIgA1 to both rAni s 1 (P cancer.

  6. THE CONCEPTUAL BASIS FOR THE DEVELOPMENT OF SMALL BUSINESS POTENTIAL IN THE REGION

    Directory of Open Access Journals (Sweden)

    Nataliia Hryshyna

    2017-12-01

    Full Text Available The article deals with the study of conceptual foundations of the development of the potential of small business in the region. The purpose of the article is to study the essence and features of small business potential and to form conceptual foundations of its development at the regional level. The subject of the research is theoretical, methodological, and practical aspects of the potential of small business in providing a sustainable economic growth. In the course of the research, the following general scientific and special methods are used: dialectical, system analysis, graphical analysis, matrix, mathematical modelling in economics, and logical generalization of results. The essence of the category “small business potential of the region” is studied; it should be understood as a complex system of balanced and mutually related elements in the form of conditions, resources, and opportunities for small business enterprises in the region to conduct production, economic, commercial, and other activities in order to ensure public needs in terms of sustainable economic growth. Methodological principles for forming a conceptual model for the development of small business potential and the scheme of generalized stages of its implementation (preparatory, analytical, operational stages and stage of introduction and implementation are determined, the implementation of which will help to determine the preconditions for the formation of strategic potential, assess its modern quantitative and qualitative composition, and make a forecast of prospects of the use in ensuring sustainable economic growth. It is proposed to use economic and mathematical models, by means of which it is possible to quantitatively describe the connection between the input indicators of the economic system and the performance indicator. In order to substantiate directions of development of the potential of small business in the region in view of its role in creating new jobs

  7. Mechanism Of Environmental Franchising In The Sustainable Development Potential

    OpenAIRE

    Inna Illyashenko

    2011-01-01

    Reveals the types of environmental franchising: franchise environmental goods, manufacturing, service and environmental business format. Presents the methodological principles for the formation mechanisms of environmental franchise in implementing sustainable development potential. Proved economic, legal and organizational technology contractual relations regarding environmental franchise.

  8. RADON BASELINE MONITORING AROUND A POTENTIAL SHALE GAS DEVELOPMENT SITE IN YORKSHIRE, ENGLAND.

    Science.gov (United States)

    Daraktchieva, Z; Wasikiewicz, J M; Howarth, C B; Bradley, E J

    2017-11-01

    The Vale of Pickering in Yorkshire, England has been identified as a potential area for shale gas extraction. Public Health England joined a collaboration led by the British Geological Survey for environmental baseline monitoring near the potential shale gas extraction site following a grant award from UK Government Department for Business, Energy and Industrial Strategy. The analysis of results for the first 6 months of indoor monitoring indicated that the results followed a log-normal distribution. The numbers of homes found to be at or above the Action Level followed the numbers predicted by the radon potential maps. The results from the measurements of outdoor air in this study indicated that the radon concentrations are slightly higher than previously measured but close to the detection limit of the technique. © The Author 2017. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  9. GABAergic transmission and chloride equilibrium potential are not modulated by pyruvate in the developing optic tectum of Xenopus laevis tadpoles.

    Directory of Open Access Journals (Sweden)

    Arseny S Khakhalin

    Full Text Available In the developing mammalian brain, gamma-aminobutyric acid (GABA is thought to play an excitatory rather than an inhibitory role due to high levels of intracellular Cl(- in immature neurons. This idea, however, has been questioned by recent studies which suggest that glucose-based artificial cerebrospinal fluid (ACSF may be inadequate for experiments on immature and developing brains. These studies suggest that immature neurons may require alternative energy sources, such as lactate or pyruvate. Lack of these other energy sources is thought to result in artificially high intracellular Cl(- concentrations, and therefore a more depolarized GABA receptor (GABAR reversal potential. Since glucose metabolism can vary widely among different species, it is important to test the effects of these alternative energy sources on different experimental preparations. We tested whether pyruvate affects GABAergic transmission in isolated brains of developing wild type Xenopus tadpoles in vitro by recording the responsiveness of tectal neurons to optic nerve stimulation, and by measuring currents evoked by local GABA application in a gramicidin perforated patch configuration. We found that, in contrast with previously reported results, the reversal potential for GABAR-mediated currents does not change significantly between developmental stages 45 and 49. Partial substitution of glucose by pyruvate had only minor effects on both the GABA reversal potential, and the responsiveness of tectal neurons at stages 45 and 49. Total depletion of energy sources from the ACSF did not affect neural responsiveness. We also report a strong spatial gradient in GABA reversal potential, with immature cells adjacent to the lateral and caudal proliferative zones having more positive reversal potentials. We conclude that in this experimental preparation standard glucose-based ACSF is an appropriate extracellular media for in vitro experiments.

  10. Biofuel developments in Mozambique. Update and analysis of policy, potential and reality

    International Nuclear Information System (INIS)

    Schut, Marc; Slingerland, Maja; Locke, Anna

    2010-01-01

    Climate change, rising oil prices and concerns about future energy supplies have contributed to a growing interest in using biomass for energy purposes. Several studies have highlighted the biophysical potential of biofuel production on the African continent, and analysts see Mozambique as one of the most promising African countries. Favorable growing conditions and the availability of land, water and labor are mentioned as major drivers behind this potential. Moreover, the potential of biofuel production to generate socio-economic benefits is reflected in the government's policy objectives for the development of the sector, such as reducing fuel import dependency and creating rural employment. This article provides an overview of biofuel developments in Mozambique and explores to what extent reality matches the suggested potential in the country. We conclude that biofuel developments mainly take place in areas near good infrastructure, processing and storage facilities, where there is (skilled) labor available, and access to services and goods. Moreover, our analysis shows the need to timely harmonize current trends in biofuel developments with the government's policy objectives as the majority of existing and planned projects are not focusing on remote rural areas, and - in absence of domestic markets - principally target external markets.

  11. Adipocytes and abdominal aortic aneurysm: Putative potential role of adipocytes in the process of AAA development.

    Science.gov (United States)

    Kugo, Hirona; Moriyama, Tatsuya; Zaima, Nobuhiro

    2018-01-15

    Background Adipose tissue plays a role in the storage of excess energy as triglycerides (TGs). Excess fat accumulation causes various metabolic and cardiovascular diseases. It has been reported that ectopic fat deposition and excess TG accumulation in non-adipose tissue might be important predictors of cardiometabolic and vascular risk. For example, ectopic fat in perivascular tissue promotes atherosclerotic plaque formation in the arterial wall. Objective Recently, it has been reported that ectopic fat (adipocyte) in the vascular wall of an abdominal aortic aneurysm (AAA) is present in both human and experimental animal models. The pathological significance of adipocytes in the AAA wall has not been fully understood. In this review, we summarized the functions of adipocytes and discussed potential new drugs that target vascular adipocytes for AAA treatment. Result Previous studies suggest that adipocytes in vascular wall play an important role in the development of AAA. Conclusion Adipocytes in the vascular wall could be novel targets for the development of AAA therapeutic drugs. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.org.

  12. Ecthyma gangrenosum in the periorbital region in a previously healthy immunocompetent woman without bacteremia

    Directory of Open Access Journals (Sweden)

    Somenath Sarkar

    2016-01-01

    Full Text Available Ecthyma gangrenosum (EG is a cutaneous lesion classically associated with potentially fatal Pseudomonas septicemia in immunocompromised patients. Other bacterial and fungal pathogens have also been implicated. Although EG typically occurs in immunocompromised or neutropenic patients, it may occasionally affect a previously healthy person. The cutaneous findings are characteristic with small indurated papulovesicles progressing rapidly to necrotic ulcers with surrounding erythema and a central black Eschar. While lesions can occur at any site, most are commonly found over the buttocks, perineum, limbs, and axillae. We describe a case of EG in periorbital region in a previously healthy woman who responded to appropriate antibiotic treatment for Pseudomonas. It is very important to establish the diagnosis early so that appropriate systemic antibiotic therapy can be initiated to reduce morbidity and potential mortality.

  13. Arts Integration as Potentiality for Professional Development for Teachers

    DEFF Research Database (Denmark)

    Jensen, Julie Borup; McCandless, Peggy

    2013-01-01

    This paper investigates the potentialities for professional development, when teachers work with integration of arts and academic subjects in the classroom. The idea of integrating arts and academic subjects can be seen as a way of experimenting with teaching. Experiments in the classroom as a wa...

  14. Targeting Alzheimer's disease by investigating previously unexplored chemical space surrounding the cholinesterase inhibitor donepezil

    CSIR Research Space (South Africa)

    Van Greunen, DG

    2017-02-01

    Full Text Available A series of twenty seven acetylcholinesterase inhibitors, as potential agents for the treatment of Alzheimer's disease, were designed and synthesised based upon previously unexplored chemical space surrounding the molecular skeleton of the drug...

  15. Laparoscopy After Previous Laparotomy

    Directory of Open Access Journals (Sweden)

    Zulfo Godinjak

    2006-11-01

    Full Text Available Following the abdominal surgery, extensive adhesions often occur and they can cause difficulties during laparoscopic operations. However, previous laparotomy is not considered to be a contraindication for laparoscopy. The aim of this study is to present that an insertion of Veres needle in the region of umbilicus is a safe method for creating a pneumoperitoneum for laparoscopic operations after previous laparotomy. In the last three years, we have performed 144 laparoscopic operations in patients that previously underwent one or two laparotomies. Pathology of digestive system, genital organs, Cesarean Section or abdominal war injuries were the most common causes of previouslaparotomy. During those operations or during entering into abdominal cavity we have not experienced any complications, while in 7 patients we performed conversion to laparotomy following the diagnostic laparoscopy. In all patients an insertion of Veres needle and trocar insertion in the umbilical region was performed, namely a technique of closed laparoscopy. Not even in one patient adhesions in the region of umbilicus were found, and no abdominal organs were injured.

  16. Potential of wind power projects under the Clean Development Mechanism in India

    Directory of Open Access Journals (Sweden)

    Michaelowa Axel

    2007-07-01

    Full Text Available Abstract Background So far, the cumulative installed capacity of wind power projects in India is far below their gross potential (≤ 15% despite very high level of policy support, tax benefits, long term financing schemes etc., for more than 10 years etc. One of the major barriers is the high costs of investments in these systems. The Clean Development Mechanism (CDM of the Kyoto Protocol provides industrialized countries with an incentive to invest in emission reduction projects in developing countries to achieve a reduction in CO2 emissions at lowest cost that also promotes sustainable development in the host country. Wind power projects could be of interest under the CDM because they directly displace greenhouse gas emissions while contributing to sustainable rural development, if developed correctly. Results Our estimates indicate that there is a vast theoretical potential of CO2 mitigation by the use of wind energy in India. The annual potential Certified Emissions Reductions (CERs of wind power projects in India could theoretically reach 86 million. Under more realistic assumptions about diffusion of wind power projects based on past experiences with the government-run programmes, annual CER volumes by 2012 could reach 41 to 67 million and 78 to 83 million by 2020. Conclusion The projections based on the past diffusion trend indicate that in India, even with highly favorable assumptions, the dissemination of wind power projects is not likely to reach its maximum estimated potential in another 15 years. CDM could help to achieve the maximum utilization potential more rapidly as compared to the current diffusion trend if supportive policies are introduced.

  17. Mammography - recent technical developments and their clinical potential

    Energy Technology Data Exchange (ETDEWEB)

    Hemdal, Bengt; Mattsson, Soeren [Malmoe Univ. Hospital (Sweden). Dept. of Radiation Physics; Andersson, Ingvar [Malmoe Univ. Hospital (Sweden). Dept. of Diagnostic Radiology; Thilander Klang, Anne [Sahlgrenska Univ. Hospital, Goeteborg (Sweden). Dept. of Medical Physics and Biomedical Engineering; Bengtsson, Gert; Jarlman, O. [Lund Univ. Hospital (Sweden). Dept. of Diagnostic Radiology; Leitz, Wolfram [Swedish Radiation Protection Authority, Stockholm (Sweden); Bjurstam, Nils [Univ. of North Norway, Troms (Norway). Dept. of Radiology

    2002-05-01

    The recent technical developments in digital as well as screen-film X-ray mammography have been reviewed in order to evaluate their clinical potential and to analyse possible lines for future development. Material and methods: The scientific literature has been reviewed, conferences covered and contacts with colleagues developed. Companies in the field have been inquired and invited for presentations. Own experience has been gathered from different screen-film and digital mammography systems. Results and conclusions: Although there are important complementary techniques such as ultrasound and magnetic resonance imaging (MRI), X-ray mammography is still the golden standard for breast imaging. It is relatively simple and cost-effective, and it is presently the only realistic technique for screening in a large scale. It is still largely the only technique that can detect breast cancer in a pre invasive stage. Equipment for digital mammography is commercially available both with small area and full field technique (FFDM). The development of FFDM systems is now intense, as well as the development of dedicated workstations and computer-aided detection (CAD). In spite of this, the introduction of digital mammography has been very slow compared to most other X-ray examinations due to high costs and technical challenges to meet the high demands on image quality and dose in mammography as well as the demands on specialised workflow support for screening mammography and suitable display techniques. Film reading of digital mammograms has been the most common display mode so far, but to take full advantage of the digital concept, diagnostic as well as logistic, monitor reading must be applied. There is a potential of FFDM systems for significantly higher image quality or significantly lower dose than screen-film mammography (SFM), or both. Further research is necessary to fully use this potential. The investment costs are much higher for digital than screen-film mammography

  18. Mammography - recent technical developments and their clinical potential

    International Nuclear Information System (INIS)

    Hemdal, Bengt; Mattsson, Soeren; Bjurstam, Nils

    2002-05-01

    The recent technical developments in digital as well as screen-film X-ray mammography have been reviewed in order to evaluate their clinical potential and to analyse possible lines for future development. Material and methods: The scientific literature has been reviewed, conferences covered and contacts with colleagues developed. Companies in the field have been inquired and invited for presentations. Own experience has been gathered from different screen-film and digital mammography systems. Results and conclusions: Although there are important complementary techniques such as ultrasound and magnetic resonance imaging (MRI), X-ray mammography is still the golden standard for breast imaging. It is relatively simple and cost-effective, and it is presently the only realistic technique for screening in a large scale. It is still largely the only technique that can detect breast cancer in a pre invasive stage. Equipment for digital mammography is commercially available both with small area and full field technique (FFDM). The development of FFDM systems is now intense, as well as the development of dedicated workstations and computer-aided detection (CAD). In spite of this, the introduction of digital mammography has been very slow compared to most other X-ray examinations due to high costs and technical challenges to meet the high demands on image quality and dose in mammography as well as the demands on specialised workflow support for screening mammography and suitable display techniques. Film reading of digital mammograms has been the most common display mode so far, but to take full advantage of the digital concept, diagnostic as well as logistic, monitor reading must be applied. There is a potential of FFDM systems for significantly higher image quality or significantly lower dose than screen-film mammography (SFM), or both. Further research is necessary to fully use this potential. The investment costs are much higher for digital than screen-film mammography

  19. Co-development in the food industry: Status and potential advantages

    DEFF Research Database (Denmark)

    Olsen, Johanne R.; Harmsen, Hanne

    practice - co-development. Co-development gives the involved companies competitive advantages in the face of product imitation and globalization issues. An empirical study in the Danish food industry was performed to uncover tendencies in co-development activities and the potential for further development......The food industry is faced with new challenges. The need for fast solutions and convenience - and thus more complex products - is increasing as e.g. demographics and the every-day life of food consumers are changing. Companies have to break down traditional barriers to allow room for a new best...

  20. DISTANCE LEARNING: POTENTIAL APPLICATION AND DEVELOPMENT OUTLOOK

    Directory of Open Access Journals (Sweden)

    Yulija Mihajlovna Tsarapkina

    2017-11-01

    Full Text Available The article is devoted to the actual problem of distance education potential and prospects research in the Russian education system. According to the UNESCO estimates, if the current trend continues, then the number of people with a firm desire to receive an education would increase from 165 millions to 263 millions [7, 12]. Thus 98 million qualified students worldwide will be excluded from higher education due to a shortage of university seats. The purpose of the study is to analyze the historical and present state of the problem, to identify the potential and prospects of the development in distance learning within higher education. The methodological base of the research has become common methods of pedagogical sciences: pedagogical observation, survey, questionnaire, testing, comparative analysis, pedagogical experiment. The analytical review has shown several problem areas within distance learning, such as student’s motivation while distance course learning and training efficiency as compared to full-time university training. Combination of full-time training and distance learning leads to 31% enhancement of training efficiency and shows a sustainable increase of student’s motivation.

  1. Iodine-131 induced hepatotoxicity in previously healthy patients with Grave’s disease

    Science.gov (United States)

    2013-01-01

    Objective To describe the association of the rare and serious complication of liver toxicity in previously healthy Grave’s disease (GD) patients after the treatment with radioactive iodine 131I (RAI). Case presentation We report the clinical, laboratory and pathologic findings of 2 cases of severe liver toxicity associated with the treatment with RAI in previously healthy patients with GD. Clinical examination and laboratory investigations excluded viral hepatitis, autoimmune hepatitis, granulomatous disease, primary biliary disease, extrahepatic biliary obstruction, and heart failure. Case 1: A previously healthy 52-years old man reportedly having a typical GD but following RAI treatment, concomitantly developed severe liver toxicity that required 1 week of treatment in hospital. Case 2: A previously healthy 34-years old woman is reported as having a typical GD but developed jaundice following RAI treatment that required several weeks of in hospital treatment in the hepato-biliary department. In both cases, the liver dysfunction resolved after intensive treatment with hepato-protective agents. In this report the therapeutic considerations as well as the pathogenetic possibilities are reviewed. Conclusion To the best of our knowledge, this is the first description of the association observed, which is rare but may be severe and should be considered in any case of thyrotoxicosis where a liver dysfunction develops after the treatment with radioactive iodine 131I. PMID:23497434

  2. Personality disorders in previously detained adolescent females: a prospective study

    NARCIS (Netherlands)

    Krabbendam, A.; Colins, O.F.; Doreleijers, T.A.H.; van der Molen, E.; Beekman, A.T.F.; Vermeiren, R.R.J.M.

    2015-01-01

    This longitudinal study investigated the predictive value of trauma and mental health problems for the development of antisocial personality disorder (ASPD) and borderline personality disorder (BPD) in previously detained women. The participants were 229 detained adolescent females who were assessed

  3. On the assessment of cross-border regions' development potential

    Directory of Open Access Journals (Sweden)

    Bilchak Mikhail

    2011-06-01

    Full Text Available This article sets out to assess the potential of cross-border region development on the basis of theoretical and methodological materials. The study examines the Kaliningrad region and Warmian-Masurian Voivodeship. The article is focused on the modelling of interindustry balance and export/import functions of border territories.

  4. Developing Potential Candidates of Preclinical Preeclampsia

    Directory of Open Access Journals (Sweden)

    Sandra Founds

    2015-11-01

    Full Text Available The potential for developing molecules of interest in preclinical preeclampsia from candidate genes that were discovered on gene expression microarray analysis has been challenged by limited access to additional first trimester trophoblast and decidual tissues. The question of whether these candidates encode secreted proteins that may be detected in maternal circulation early in pregnancy has been investigated using various proteomic methods. Pilot studies utilizing mass spectrometry based proteomic assays, along with enzyme linked immunosorbent assays (ELISAs, and Western immunoblotting in first trimester samples are reported. The novel targeted mass spectrometry methods led to robust multiple reaction monitoring assays. Despite detection of several candidates in early gestation, challenges persist. Future antibody-based studies may lead to a novel multiplex protein panel for screening or detection to prevent or mitigate preeclampsia.

  5. Preoperative screening: value of previous tests.

    Science.gov (United States)

    Macpherson, D S; Snow, R; Lofgren, R P

    1990-12-15

    To determine the frequency of tests done in the year before elective surgery that might substitute for preoperative screening tests and to determine the frequency of test results that change from a normal value to a value likely to alter perioperative management. Retrospective cohort analysis of computerized laboratory data (complete blood count, sodium, potassium, and creatinine levels, prothrombin time, and partial thromboplastin time). Urban tertiary care Veterans Affairs Hospital. Consecutive sample of 1109 patients who had elective surgery in 1988. At admission, 7549 preoperative tests were done, 47% of which duplicated tests performed in the previous year. Of 3096 previous results that were normal as defined by hospital reference range and done closest to the time of but before admission (median interval, 2 months), 13 (0.4%; 95% CI, 0.2% to 0.7%), repeat values were outside a range considered acceptable for surgery. Most of the abnormalities were predictable from the patient's history, and most were not noted in the medical record. Of 461 previous tests that were abnormal, 78 (17%; CI, 13% to 20%) repeat values at admission were outside a range considered acceptable for surgery (P less than 0.001, frequency of clinically important abnormalities of patients with normal previous results with those with abnormal previous results). Physicians evaluating patients preoperatively could safely substitute the previous test results analyzed in this study for preoperative screening tests if the previous tests are normal and no obvious indication for retesting is present.

  6. [Incidence and clinical risk factors for the development of diabetes mellitus in women with previous gestational diabetes].

    Science.gov (United States)

    Domínguez-Vigo, P; Álvarez-Silvares, E; Alves-Pérez M T; Domínguez-Sánchez, J; González-González, A

    2016-04-01

    Gestational diabetes is considered a variant of diabetes mellitus as they share a common pathophysiological basis: insulin resistance in target and insufficient secretion of it by pancreatic p-cell bodies. Pregnancy is a unique physiological situation provides an opportunity to identify future risk of diabetes mellitus. To determine the long-term incidence of diabetes mellitus in women who have previously been diagnosed with gestational diabetes and identifying clinical risk factors for developing the same. nested case-control cohort study. 671 patients between 1996 and 2009 were diagnosed with gestational diabetes were selected. The incidence of diabetes mellitus was estimated and 2 subgroups were formed: Group A or cases: women who develop diabetes mellitus after diagnosis of gestational diabetes. Group B or control: random sample of 71 women with a history of gestational diabetes in the follow-up period remained normoglycemic. Both groups were studied up to 18 years postpartum. By studying Kaplan Meier survival of the influence of different gestational variables it was obtained in the later development of diabetes mellitus with time parameter and COX models for categorical variables were applied. Significant variables were studied by multivariate Cox analysis. In all analyzes the Hazard ratio was calculated with confidence intervals at 95%. The incidence of diabetes mellitus was 10.3% in patients with a history of gestational diabetes. They were identified as risk factors in the index pregnancy to later development of diabetes mellitus: greater than 35 and younger than 27 years maternal age, BMI greater than 30 kg/m2, hypertensive disorders of pregnancy, insulin therapy, poor metabolic control and more than a complicated pregnancy with gestational diabetes. Clinical factors have been identified in the pregnancy complicated by gestational diabetes that determine a higher probability of progression to diabetes mellitus in the medium and long term.

  7. Fast optimization of statistical potentials for structurally constrained phylogenetic models

    Directory of Open Access Journals (Sweden)

    Rodrigue Nicolas

    2009-09-01

    Full Text Available Abstract Background Statistical approaches for protein design are relevant in the field of molecular evolutionary studies. In recent years, new, so-called structurally constrained (SC models of protein-coding sequence evolution have been proposed, which use statistical potentials to assess sequence-structure compatibility. In a previous work, we defined a statistical framework for optimizing knowledge-based potentials especially suited to SC models. Our method used the maximum likelihood principle and provided what we call the joint potentials. However, the method required numerical estimations by the use of computationally heavy Markov Chain Monte Carlo sampling algorithms. Results Here, we develop an alternative optimization procedure, based on a leave-one-out argument coupled to fast gradient descent algorithms. We assess that the leave-one-out potential yields very similar results to the joint approach developed previously, both in terms of the resulting potential parameters, and by Bayes factor evaluation in a phylogenetic context. On the other hand, the leave-one-out approach results in a considerable computational benefit (up to a 1,000 fold decrease in computational time for the optimization procedure. Conclusion Due to its computational speed, the optimization method we propose offers an attractive alternative for the design and empirical evaluation of alternative forms of potentials, using large data sets and high-dimensional parameterizations.

  8. Validation of a Previously Developed Geospatial Model That Predicts the Prevalence of Listeria monocytogenes in New York State Produce Fields

    Science.gov (United States)

    Weller, Daniel; Shiwakoti, Suvash; Bergholz, Peter; Grohn, Yrjo; Wiedmann, Martin

    2015-01-01

    Technological advancements, particularly in the field of geographic information systems (GIS), have made it possible to predict the likelihood of foodborne pathogen contamination in produce production environments using geospatial models. Yet, few studies have examined the validity and robustness of such models. This study was performed to test and refine the rules associated with a previously developed geospatial model that predicts the prevalence of Listeria monocytogenes in produce farms in New York State (NYS). Produce fields for each of four enrolled produce farms were categorized into areas of high or low predicted L. monocytogenes prevalence using rules based on a field's available water storage (AWS) and its proximity to water, impervious cover, and pastures. Drag swabs (n = 1,056) were collected from plots assigned to each risk category. Logistic regression, which tested the ability of each rule to accurately predict the prevalence of L. monocytogenes, validated the rules based on water and pasture. Samples collected near water (odds ratio [OR], 3.0) and pasture (OR, 2.9) showed a significantly increased likelihood of L. monocytogenes isolation compared to that for samples collected far from water and pasture. Generalized linear mixed models identified additional land cover factors associated with an increased likelihood of L. monocytogenes isolation, such as proximity to wetlands. These findings validated a subset of previously developed rules that predict L. monocytogenes prevalence in produce production environments. This suggests that GIS and geospatial models can be used to accurately predict L. monocytogenes prevalence on farms and can be used prospectively to minimize the risk of preharvest contamination of produce. PMID:26590280

  9. Survey of renewable energy utilization and development potential in Oceania

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-03-01

    This paper reports fiscal 2000 survey of renewable energy utilization and development potential in Oceania. In Australia and New Zealand, renewable energy has already fairly been used. In Australia, it is promoted on the government policy level, with cost reduction and improved reliability in progress. The growth of 2% is set as a target in the year 2010. Promising are biomass and wind, while contributory in the long run are photovoltaic energies. New installations of hydraulic power generation are few, but potential is high for mini hydraulic power generation. Social interest is also comparatively high in renewable energies and greenhouse effect gas. However, further technological development is necessary for a full-scale contribution to global environmental problems. The situation in other south Pacific nations depends on their policy, economic condition and level of industrialization; each country heavily imports diesel oil for power generation, is under-developed industry-wise, and is a low income nation. The countries are desperately in need of foreign investment for the purpose of solving these problems. (NEDO)

  10. Economic development and foreign direct investment: How to create sustainable development an analysis of the potential for sustainable development on the Indian subcontinent

    Directory of Open Access Journals (Sweden)

    Homlong Nathalie

    2010-01-01

    Full Text Available Focusing critically on the effects of the conditions for foreign direct investment on sustainable growth in the recipient country, this paper analyzes the potential for investments in environmental innovations in India. The definition of sustainability applied in this paper incorporates economic development and investment which promotes environmentally and socially friendly production and innovation. As the Indian economy experienced strong growth in GDP in recent years, but is still lagging behind in providing the basic needs of clean water, clean air and proper waste management for households and companies, the necessity for sustainable development exists. From a methodological point of view this paper uses macroeconomic data to evaluate quantitatively the potentials and needs of Indian states. This results in a state ranking showing the potential for sustainable development in selected Indian states, based on economic and environmental indicators.

  11. Application of potential

    International Nuclear Information System (INIS)

    Petris, L.

    1979-01-01

    This report summarizes the results obtained with the nucleon-nucleon potential presented previously for: 1) the deuteron properties and wave function, 2) a Hartree-Fock calculation on O 16 , and 3) the perturbation V-matrix and G-matrix results for the potential in relation to the results of other potentials and to saturation

  12. Potential interest in Europe in SPS development

    Energy Technology Data Exchange (ETDEWEB)

    Reinhartz, K K

    1980-06-01

    The Solar Satellite Power System is a concept whereby large solar-energy converters are placed in outer space and the electrical energy produced is transmitted back to earth as microwave radiation. A number of studies, performed mainly in the United States, are aimed at assessing the technical, economic, social and health aspects of this concept. This paper does not address the feasibility of the SPS as such, but discusses the potential contribution that an SPS could make to the European energy scenario, the economic impact of the SPS as an indigenous European energy source, and the potential importance of the SPS as a technology driver. A European network of forty solar power satellites could supply electrical energy equal to Europe's present electrical energy production and significantly reduce Europe's dependence on energy imports. Additionally the development of a power satellite technology, if started by the United States, is expected to lead to such an advancement in technology in key areas, e.g., space industrialisation, photovoltaic energy conversion and wireless transmission of energy, that Europe would rapidly lose technical competence in many important fields if it were not to participate.

  13. Potential carbon impacts of smart grid development in six European countries

    Energy Technology Data Exchange (ETDEWEB)

    Darby, S. [Lower Carbon Futures, Environmental Change Institute, Oxford University, South Parks Road, Oxford, OX1 3QY (United Kingdom); Stroembaeck, J. [VaasaETT Global Energy Think Tank, Itaemerenkatu 5, 2nd floor, 00180 Helsinki (Finland); Wilks, M. [Poyry Management Consulting, King Charles House, Park End Street, Oxford, OX1 1JD (United Kingdom)

    2013-11-15

    This paper examines reports on work carried out for the European Commission to devise a methodology for estimating the potential impact of smart grids on carbon emissions. It first identifies functionalities that enable carbon benefits to be realised. Each functionality on the demand side is assumed to be mirrored on the supply side, as when dynamic peak shifting 'replaces' flexible peak generation. Metrics are developed to describe the state of markets and to estimate customer response to demand response initiatives. Quantitative analysis identifies where the greatest scope for emissions reduction lies, while qualitative assessment indicates where to expect more or less impact from smart grid deployment. The impact of smart grid functionalities by 2020 is then modelled for six representative EU markets (Austria, France, Germany, Great Britain, Portugal and Spain), using a detailed pan-European market model and also a high-level ancillary services model. Three scenarios are developed: baseline, in which no smart grid rollout is assumed; feasible, based on what could be achievable in the light of technology developments and with supportive legislation; and an intermediate expected scenario, in which new technologies are introduced but nothing else changes. The findings indicate the potential for emissions reductions by 2020. They also show that the potential is very unlikely to be reached without regulatory support for user engagement in demand response and demand reduction, along with enabling technology and programmes. Development of regulatory frameworks that allow full advantage to be taken of the new technologies emerges as a challenge for smart grid development.

  14. The potential of net zero energy buildings (NZEBs) concept at design stage for healthcare buildings towards sustainable development

    Science.gov (United States)

    Hazli Abdellah, Roy; Asrul Nasid Masrom, Md; Chen, Goh Kai; Mohamed, Sulzakimin; Omar, Roshartini

    2017-11-01

    The focus on net-zero energy buildings (NZEBs) has been widely analysed and discussed particularly when European Union Parliament are progressively moving towards regulation that promotes the improvement of energy efficiency (EE). Additionally, it also to reduce energy consumption through the recast of the EU Directive on Energy Performance of Buildings (EPBD) in which all new buildings to be “nearly Zero-Energy” Buildings by 2020. Broadly, there is a growing trend to explore the feasibility of net zero energy in healthcare sector as the level energy consumption for healthcare sector is found significantly high. Besides that, healthcare buildings energy consumption also exceeds of many other nondomestic building types, and this shortcoming is still undetermined yet especially for developing countries. This paper aims to review the potential of NZEBs in healthcare buildings by considering its concept in design features. Data are gathered through a comprehensive energy management literature review from previous studies. The review is vital to encourage construction players to increase their awareness, practices, and implementation of NZEBs in healthcare buildings. It suggests that NZEBs concept has a potential to be adapted in healthcare buildings through emphasizing of passive approach as well as the utilization of energy efficiency systems and renewable energy systems in buildings. This paper will provide a basis knowledge for construction key players mainly architects to promote NZEBs concept at design stage for healthcare buildings development.

  15. How to make the clean development mechanism sustainable-The potential of rent extraction

    International Nuclear Information System (INIS)

    Muller, Adrian

    2007-01-01

    The clean development mechanism (CDM) should foster sustainable development and greenhouse gas emission reductions. The design of the CDM and first experience suggest that it may not achieve these goals. Developing countries hosting CDM projects may lose cheap emission reduction possibilities for their own future use, and sustainable development and technology transfer may not take place. On the other hand, the CDM has the potential to generate considerable rents if permit prices are high or costs low. To account for equity and distributional issues, a deliberate decision on how to distribute these rents could be taken and the potential failure of the CDM in meeting its goals calls for some further regulation. I suggest to combine these two issues and to extract the rents by a profit tax. Ideally, the tax revenues could contribute to national sustainable development strategies, to offset external costs imposed by CDM projects and to extract part of the resource rent they may generate. The international character of the CDM could offer a frame for internationally coordinated tax design. This would hedge against a potential race to the bottom

  16. Protein Supplement Usage Among Male University Students: Comparisons Between Current and Previous Users.

    Science.gov (United States)

    Sung, Youngmo; Choi, Jinkyung

    2018-02-01

    Interest in specialized dietary supplements is leading market growth, and protein supplements are popular for increasing muscle mass among young males. Therefore, this study investigated the attitudes toward and satisfaction with protein supplements to identify detailed consumer behaviors related to the consumption of protein supplements. The study sample includes male university students in their 20s in South Korea. In total, 223 responses were entered for analysis. Questions related to attitudes, satisfaction, and future behavioral intentions were asked using 5-point Likert scales. The responses were divided into two groups, current and previous users, to identify significant differences in terms of attitudes, satisfaction, and future behavioral intentions. A descriptive analysis, analysis of variance (ANOVA), and multiple regression were run. The majority of respondents prefer the powdered form of supplements in bulk with a price range between 30,000 won and 60,000 won. Online shopping was preferred, while word of mouth and friends/family were considered credible information sources. The most common side effects experienced were problems with digestion and hives, although more than 78% did not experience side effects. In comparison between current and previous users in terms of attitudes and satisfaction, the following areas showed significances. Regarding attitudes, the importance of brand, preference for products from overseas, the search for nutritional facts, and reading carefully all product information were significant, while regarding satisfaction, price, effectiveness, and ease of consumption were significant. All significances showed that current users had more positive attitudes and greater satisfaction. Overall, consumers' satisfaction regarding ease of consumption influenced future behavioral intentions. The market for protein supplements has been growing, so measuring consumers' attitudes and satisfaction would help attract potential consumers. In

  17. INNOVATION POTENTIAL: IMPACT ON THE NATIONAL ECONOMY’S COMPETITIVENESS OF THE EU DEVELOPED COUNTRIES

    Directory of Open Access Journals (Sweden)

    Iryna Lomachynska

    2018-01-01

    Full Text Available The success of the economy of each country is determined by its innovation development. The purpose of the paper is to investigate the essence of innovation potential and its role in providing the national economy’s competitiveness under the conditions of technological changes on the example of the European Union developed countries. The subject of research is the innovation potential of Austria and Germany. Methodology. The study is based on a comparative analysis of approaches to determination and evaluation of innovation potential in specialized economic literature. Analysis and synthesis and the system approach were used to outline the entity of innovation potential, to explore and structure its elements in the context of providing the national economy’s competitiveness. The quality and quantity analysis were used to discover general characteristics of the EU countries’ innovation development, special aspects of the national innovation systems of Austria and Germany, the role of innovation potential in the national economies competitiveness of these countries. The method of mathematical modelling in economics, in particular, regression analysis based on annual data for the period from 1995 to 2015, was applied to assess the impact of innovation potential on the Austria and Germany competitiveness. The absolute value of GDP and the share of export of goods and services in GDP are used as a dependent variable. Elements that characterize the country’s innovation potential were used as independent variables: the share of researchers in R&D of total population, the share of labour force with advanced education of total working-age population with advanced education, expenditure on tertiary education as a percentage of GDP, R&D expenditure as a percentage of GDP, patent applications as a percentage of total population. Results of the survey of theoretical works showed that the most multifaceted and comprehensive approach to determining the

  18. The potential contribution of social impact assessment to megaproject developments

    NARCIS (Netherlands)

    Vanclay, Francis; Lehtonen, Markku; Joly, Pierre-Benoît; Aparicio, Luis

    2017-01-01

    Megaprojects have considerable potential to generate social impacts as well as environmental impacts. These social impacts occur at all phases in project development. Megaprojects tend to cause the displacement and resettlement of people, as well as induce inmigration and local inflation. They

  19. Contribution to the heavy-ion optical potential from coupling to vibrational states

    Energy Technology Data Exchange (ETDEWEB)

    Donangelo, R; Canto, L F; Hussein, M S

    1978-11-01

    The component of the optical potential in the elastic channel due to the coupling to vibrational states in Coulomb excitation is derived using a previously developed semiclassical method. Several numerical examples are worked out.

  20. Canada's potential role in the Clean Development Mechanism

    International Nuclear Information System (INIS)

    Pape-Salmon, A.

    2000-01-01

    The role that Canada might play in the Kyoto Protocol's Clean Development Mechanism (CDM) is discussed. The CDM prescribes the way in which industrialized countries could create emission reduction credits for greenhouse gas emission reduction projects in developing countries which, in turn they could use to meet their own commitments and possibly reduce their cost of compliance with the Kyoto Protocol. While Canada does not see itself as a CDM project investor, it strongly supports private sector involvement in the CDM and believes that it has a role to play in assisting CDM investments by the Canadian private sector by facilitating desirable outcomes via international negotiations on the rules and modalities for the CDM which would minimize transaction costs; give prominence to aspects that Canada recognizes as necessary precursors to mobilizing private sector involvement in CDM activities; maximize the flexibility for use of the CDM; allow for conversion of credits between different Kyoto Mechanisms; allow for the certification of emissions sequestration from sinks; and maximize the environmental and sustainable development benefits of CDM projects. Canada also supports, along with the other members of the 'Umbrella group', the fewest possible restrictions and significant autonomy to the private sector to implement a variety of project activities in developing countries. This report provides a detailed examination of the Canadian government's views on the CDM, Canada's participation in international emission reduction projects, the factors that drive Canadian demand for greenhouse gas emission reduction offsets and the potential demand for CDM offsets, Canada's greenhouse gas emission inventory and projections, the approach of Canadian corporate investors in the CDM and Canadian technology and expertise in greenhouse gas emission reductions. Various appendices to the report contain further details on a number of cooperation agreements between Canada and other

  1. MULTIDIMENSIONAL MODELING TOOL OF POTENTIAL EVALUATION OF REGION DEVELOPMENT

    Directory of Open Access Journals (Sweden)

    Володимир Олександрович ТІМОФЄЄВ

    2015-05-01

    Full Text Available The results of Ukrainian research of western towns are proposed for evaluation of development potential of recreational tourism and the whole tourism industry. Socio-economic factors, climatic and natural factors, state and perspectives of infrastructure in the region, political and administrative stability were chosen as evaluation parameters. The conclusion was done concerning the obtained results of rating evaluation.

  2. VBAC Scoring: Successful vaginal delivery in previous one caesarean section in induced labour

    International Nuclear Information System (INIS)

    Raja, J.F.; Bangash, K.T.; Mahmud, G.

    2013-01-01

    Objective: To develop a scoring system for the prediction of successful vaginal birth after caesarean section, following induction of labour with intra-vaginal E2 gel (Glandin). Methods: The cross-sectional study was conducted from January 2010 to August 2011, at the Pakistan Institute of Medical Sciences in Islamabad. Trial of labour in previous one caesarean section, undergoing induction with intra-vaginal E2 gel, was attempted in 100 women. They were scored according to six variables; maternal age; gestation; indications of previous caesarean; history of vaginal birth either before or after the previous caesarean; Bishop score and body mass index. Multivariate and univariate logistic regression analysis was used to develop the scoring system. Results: Of the total, 67 (67%) women delivered vaginally, while 33 (33%) ended in repeat caesarean delivery. Among the subjects, 55 (55%) women had no history of vaginal delivery either before or after previous caesarean section; 15 (15%) had history of vaginal births both before and after the previous caesarean; while 30 (30%) had vaginal delivery only after the previous caesarean section. Rates of successful vaginal birth after caesarean increased from 38% in women having a score of 0-3 to 58% in patients scoring 4-6. Among those having a score of 7-9 and 10-12, the success rates were 71% and 86% respectively. Conclusion: Increasing scores correlated with the increasing probability of vaginal birth after caesarean undergoing induction of labour. The admission VBAC scoring system is useful in counselling women with previous caesarean for the option of induction of labour or repeat caesarean delivery. (author)

  3. Effect of previous exhaustive exercise on metabolism and fatigue development during intense exercise in humans

    DEFF Research Database (Denmark)

    Iaia, F. M.; Perez-Gomez, J.; Nordsborg, Nikolai

    2010-01-01

    The present study examined how metabolic response and work capacity are affected by previous exhaustive exercise. Seven subjects performed an exhaustive cycle exercise ( approximately 130%-max; EX2) after warm-up (CON) and 2 min after an exhaustive bout at a very high (VH; approximately 30 s), high...

  4. 34 CFR 606.24 - How does the Secretary use an applicant's performance under a previous development grant when...

    Science.gov (United States)

    2010-07-01

    ... those goals and objectives, the Secretary may— (1) Decide not to fund the applicant; or (2) Fund the..., or is making substantial progress toward fulfilling, the goals and objectives of the previous grant... did not fulfill the goals and objectives of a previous grant or is not making substantial progress...

  5. 34 CFR 607.24 - How does the Secretary use an applicant's performance under a previous development grant when...

    Science.gov (United States)

    2010-07-01

    ... objectives, the Secretary may— (1) Decide not to fund the applicant; or (2) Fund the applicant but impose... progress toward fulfilling, the goals and objectives of the previous grant, including, but not limited to... the goals and objectives of a previous grant or is not making substantial progress towards fulfilling...

  6. Geographic conditions for distribution of agriculture and potentials for tourism development on Mokra mountain

    Directory of Open Access Journals (Sweden)

    Knežević Marko

    2009-01-01

    Full Text Available This work considers important natural conditions of distribution of agricultural production, cattle breeding in particular, and also potentials for tourism development on Mokra mountain. Half-nomadic cattle breeding in mountain settlements was highly developed in recent past. It represented the main source of existence for local highlanders. Today it is neglected and in phase of dying out. The mountain disposes with excellent natural potentials for ecological and mountain tourism, but these potentials are unused.

  7. Validation of a Previously Developed Geospatial Model That Predicts the Prevalence of Listeria monocytogenes in New York State Produce Fields.

    Science.gov (United States)

    Weller, Daniel; Shiwakoti, Suvash; Bergholz, Peter; Grohn, Yrjo; Wiedmann, Martin; Strawn, Laura K

    2016-02-01

    Technological advancements, particularly in the field of geographic information systems (GIS), have made it possible to predict the likelihood of foodborne pathogen contamination in produce production environments using geospatial models. Yet, few studies have examined the validity and robustness of such models. This study was performed to test and refine the rules associated with a previously developed geospatial model that predicts the prevalence of Listeria monocytogenes in produce farms in New York State (NYS). Produce fields for each of four enrolled produce farms were categorized into areas of high or low predicted L. monocytogenes prevalence using rules based on a field's available water storage (AWS) and its proximity to water, impervious cover, and pastures. Drag swabs (n = 1,056) were collected from plots assigned to each risk category. Logistic regression, which tested the ability of each rule to accurately predict the prevalence of L. monocytogenes, validated the rules based on water and pasture. Samples collected near water (odds ratio [OR], 3.0) and pasture (OR, 2.9) showed a significantly increased likelihood of L. monocytogenes isolation compared to that for samples collected far from water and pasture. Generalized linear mixed models identified additional land cover factors associated with an increased likelihood of L. monocytogenes isolation, such as proximity to wetlands. These findings validated a subset of previously developed rules that predict L. monocytogenes prevalence in produce production environments. This suggests that GIS and geospatial models can be used to accurately predict L. monocytogenes prevalence on farms and can be used prospectively to minimize the risk of preharvest contamination of produce. Copyright © 2016, American Society for Microbiology. All Rights Reserved.

  8. Plasticity during Early Brain Development Is Determined by Ontogenetic Potential.

    Science.gov (United States)

    Krägeloh-Mann, Ingeborg; Lidzba, Karen; Pavlova, Marina A; Wilke, Marko; Staudt, Martin

    2017-04-01

    Two competing hypotheses address neuroplasticity during early brain development: the "Kennard principle" describes the compensatory capacities of the immature developing CNS as superior to those of the adult brain, whereas the "Hebb principle" argues that the young brain is especially sensitive to insults. We provide evidence that these principles are not mutually exclusive. Following early brain lesions that are unilateral, the brain can refer to homotopic areas of the healthy hemisphere. This potential for reorganization is unique to the young brain but available only when, during ontogenesis of brain development, these areas have been used for the functions addressed. With respect to motor function, ipsilateral motor tracts can be recruited, which are only available during early brain development. Language can be reorganized to the right after early left hemispheric lesions, as the representation of the language network is initially bilateral. However, even in these situations, compensatory capacities of the developing brain are found to have limitations, probably defined by early determinants. Thus, plasticity and adaptivity are seen only within ontogenetic potential; that is, axonal or cortical structures cannot be recruited beyond early developmental possibilities. The young brain is probably more sensitive and vulnerable to lesions when these are bilateral. This is shown here for bilateral periventricular white matter lesions that clearly have an impact on cortical architecture and function, thus probably interfering with early network building. Georg Thieme Verlag KG Stuttgart · New York.

  9. Identification of color development potential of quartz by Raman spectroscopy

    International Nuclear Information System (INIS)

    Alkmim, Danielle G.; Lameiras, Fernando S.; Almeida, Frederico O.T.

    2013-01-01

    Colorless quartz is usually exposed to ionizing radiation (gamma rays or high energy electron beams) to acquire different colors for jewelry. Color development is due to the presence of traces of some elements such as aluminum, iron, hydrogen, lithium, or sodium. Most quartz crystals are extracted colorless from nature and it is necessary to separate those that can develop colors from those that cannot. Irradiation tests can be used to accomplish this separation, but they take a long time. Infrared signature of colorless quartz can also be used. However, infrared spectroscopy is quite expensive, especially when using portable devices. Raman spectroscopy is now available as an inexpensive and portable technique that could provide identification of the samples of colorless quartz still in the field, facilitating the prediction for their economic exploitation. In addition, Raman spectroscopy usually requires a minimum or no sample preparation. This paper presents an investigation of the feasibility of using Raman spectroscopy as a substitute for infrared spectroscopy to predict the potential for color development of quartz. A band at 3595 cm -1 in the Raman shift spectrum was observed only along the c axis of a prasiolite excited by a high power 514 nm laser. This band was not observed in quartz samples that do not develop color after irradiation. Further studies are required to identify the potential for color development by Raman spectroscopy of other types of colorless quartz. (author)

  10. Development of Optically Active Nanostructures for Potential Applications in Sensing, Therapeutics and Imaging

    Science.gov (United States)

    Joshi, Padmanabh

    Materials at nanoscale are finding manifold applications in the various fields like sensing, plasmonics, therapeutics, to mention a few. Large amount of development has taken place regarding synthesis and exploring the novel applications of the various types of nanomaterials like organic, inorganic and hybrid of both. Yet, it is believed that the full potential of different nanomaterials is yet to be fully established stimulating researchers to explore more in the field of nanotechnology. Building on the same premise, in the following studies we have developed the nanomaterials in the class of optically active nanoparticles. First part of the study we have successfully designed, synthesized, and characterized Ag-Fe3O4 nanocomposite substrate for potential applications in quantitative Surface Enhanced Raman Scattering (SERS) measurements. Quantitative SERS-based detection of dopamine was performed successfully. In subsequent study, facile, single-step synthesis of polyethyleneimine (PEI) coated lanthanide based NaYF4 (Yb, Er) nanoparticles was developed and their application as potential photodynamic therapy agent was studied using excitations by light in near infra-red and visible region. In the following and last study, synthesis and characterization of the conjugated polymer nanoparticles was attempted successfully. Functionalization of the conjugated nanoparticles, which is a bottleneck for their potential applications, was successfully performed by encapsulating them in the silica nanoparticles, surface of which was then functionalized by amine group. Three types of optically active nanoparticles were developed for potential applications in sensing, therapeutics and imaging.

  11. Priority of VHS Development Based in Potential Area using Principal Component Analysis

    Science.gov (United States)

    Meirawan, D.; Ana, A.; Saripudin, S.

    2018-02-01

    The current condition of VHS is still inadequate in quality, quantity and relevance. The purpose of this research is to analyse the development of VHS based on the development of regional potential by using principal component analysis (PCA) in Bandung, Indonesia. This study used descriptive qualitative data analysis using the principle of secondary data reduction component. The method used is Principal Component Analysis (PCA) analysis with Minitab Statistics Software tool. The results of this study indicate the value of the lowest requirement is a priority of the construction of development VHS with a program of majors in accordance with the development of regional potential. Based on the PCA score found that the main priority in the development of VHS in Bandung is in Saguling, which has the lowest PCA value of 416.92 in area 1, Cihampelas with the lowest PCA value in region 2 and Padalarang with the lowest PCA value.

  12. China Refrigerator Information Label: Specification Development and Potential Impact

    Energy Technology Data Exchange (ETDEWEB)

    Fridley, David; Fridley, David; Zheng, Nina; Zhou, Nan; Aden, Nathaniel; Lin, Jiang; Jianhong, Cheng; Sakamoto, Tomoyuki

    2008-02-01

    In the last five years, China's refrigerator market has grown rapidly, and now urban markets are showing signs of saturation, with ownership rates in urban households reaching 92%. Rural markets continue to grow from a much lower base. As a result of this growth, the Chinese government in 2006 decided to revise the refrigerator standards and its associated efficiency grades for the mandatory energy information label. In the Chinese standards process, the efficiency grades for the information label are tied to the minimum standards. Work on the minimum standards revision began in 2006 and continued through the first half of 2007, when the draft standard was completed under the direction of the China National Institute of Standardization (CNIS). Development of the information label grades required consideration of stakeholder input, continuity with the previous grade classification, ease of implementation, and potential impacts on the market. In this process, CLASP, with the support of METI/IEEJ, collaborated with CNIS to develop the efficiency grades, providing technical input to the process, comment and advice on particular technical issues, and evaluation of the results. After three months of effort and three drafts of the final grade specifications, this work was completed. In addition, in order to effectively evaluate the impact of the label on China's market, CLASP further provided assistance to CNIS to collect data on both the efficiency distribution and product volume distribution of refrigerators on the market. The new information label thresholds to be implemented in 2008 maintain the approach first adopted in 2005 of establishing efficiency levels relative to the minimum standard, but increased the related required efficiency levels by 20% over those established in 2003 and implemented in 2005. The focus of improvement was on the standard refrigerator/freezer (class 5), which constitutes the bulk of the Chinese market. Indeed, the new

  13. THE RESOURCE POTENTIAL AND THE DEVELOPMENT STRATEGY OF COMPETITIVE ADVANTAGES IN BUSINESS STRUCTURE

    Directory of Open Access Journals (Sweden)

    Okolnishnikova Irina Yurievna

    2013-02-01

    Full Text Available The aim of the research is the development of theoretical approaches to the study of the essence and structure of the resource potential of entrepreneurship in the context of the development strategy of the competitive advantages in business structure. As the research methodology the complex of principles and tools of system and axiological approaches is used. According to the results of the conducted research, possessing the scientific novelty, the conceptual apparatus is clarified and the author's definition of the resource potential of the enterprise is given, a model of the resource potential structure in commercial organization is analyzed and the mechanism of strategy formation for sustainable competitive advantages provision of the organization on the basis of the effective use of its resource potential is identified. Area of application of the research results is the control of competitiveness in general and resource potential of entrepreneurial structures, in particular at all levels of the socio-economic system of society.

  14. Sustainable development, tourism and territory. Previous elements towards a systemic approach

    Directory of Open Access Journals (Sweden)

    Pierre TORRENTE

    2009-01-01

    Full Text Available Today, tourism is one of the major challenges for many countries and territories. The balance of payments, an ever-increasing number of visitors and the significant development of the tourism offer clearly illustrate the booming trend in this sector. This macro-economic approach is often used by the organizations in charge of tourism, WTO for instance. Quantitative assessments which consider the satisfaction of customers’ needs as an end in itself have prevailed both in tourism development schemes and in prospective approaches since the sixties.

  15. Perturbation analysis of spontaneous action potential initiation by stochastic ion channels

    KAUST Repository

    Keener, James P.

    2011-07-01

    A stochastic interpretation of spontaneous action potential initiation is developed for the Morris-Lecar equations. Initiation of a spontaneous action potential can be interpreted as the escape from one of the wells of a double well potential, and we develop an asymptotic approximation of the mean exit time using a recently developed quasistationary perturbation method. Using the fact that the activating ionic channel\\'s random openings and closings are fast relative to other processes, we derive an accurate estimate for the mean time to fire an action potential (MFT), which is valid for a below-threshold applied current. Previous studies have found that for above-threshold applied current, where there is only a single stable fixed point, a diffusion approximation can be used. We also explore why different diffusion approximation techniques fail to estimate the MFT. © 2011 American Physical Society.

  16. Neurodevelopment of Conflict Adaptation: Evidence From Event-Related Potentials

    DEFF Research Database (Denmark)

    Liu, Xiuying; Liu, Tongran; Shangguan, Fangfang

    2018-01-01

    Conflict adaptation is key in how children self-regulate and assert cognitive control in a given situation compared with a previous experience. In the current study, we analyzed event-related potentials (ERPs) to identify age-related differences in conflict adaptation. Participants of different a...... to better assimilate and accommodate potential environmental conflicts. The results may also indicate that the development of conflict adaption is affected by the specific characteristic of the different types of conflict.......Conflict adaptation is key in how children self-regulate and assert cognitive control in a given situation compared with a previous experience. In the current study, we analyzed event-related potentials (ERPs) to identify age-related differences in conflict adaptation. Participants of different...... ages (5-year-old children, 10-year-old children, and adults) were subjected to a stimulus-stimulus (S-S) conflict control task (the flanker task) and a stimulus-response (S-R) conflict control task (the Simon task). The behavioral results revealed that all age groups had reliable conflict adaptation...

  17. Eco-Tourism Potential and Development within Lake Nakuru National Park and its Catchment.

    OpenAIRE

    2004-01-01

    This report summarises the eco-tourism potentials within Lake Nakuru National Park and its catchment to promote environmental conservation and socio-economic development that involves community participation for poverty alleviation. The area is of immense importance both nationally and internationally with tremendous potential for eco-tourism development. Currently, the Park receives about 200,000 visitors per year, most of whom on average stay only for two nights. In the recent past minimal ...

  18. Energy Savings Potential and Research & Development Opportunities for Commercial Refrigeration

    Energy Technology Data Exchange (ETDEWEB)

    none,

    2009-09-01

    This study documents the energy consumption of commercial refrigeration equipment (CRE) in the U.S. and evaluated the energy savings potential of various technologies and energy efficiency measures that could be applied to such equipment. The study provided an overview of CRE applications, assessed the energy-savings potential of CRE in the U.S., outline key barriers to adoption of energy-savings technologies, and recommended opportunities for advanced energy saving technology research. The study was modeled after an earlier 1996 report by Arthur D. Little, Inc., and updated key information, examined more equipment types, and outlined long-term research and development opportunities.

  19. THEORETICAL AND PRACTICAL ASPECTS OF EXPLORATION THE INNOVATIVE ACTIVE ORGANIZATIONS’ POTENTIAL OF A BALANCED DEVELOPMENT

    Directory of Open Access Journals (Sweden)

    A. I. Khorev

    2014-01-01

    Full Text Available Summary. The concept of "potential" put into practice as a method of study permits the uncertainty associated with the absence of any information about the conditions of functioning in the future. Critical importance is the study of the potential development of an economic entity. S.I. Ozhegov noted that development - natural process changes, the transition from one state to another, more perfect, the transition from an old qualitative state to a new, simple to complex, from lowest to highest. The essential content of balanced development potential based on study of the relationship concepts of «potential of the company», «the development of an economic entity», «balanced development» have been considered in the article. Particular attention is paid to the specifics of development of innovation-active organizations. Conclusion has been made that to the timely detection of potential balanced development need a comprehensive analysis of the conditions and factors functioning economic entity, which have been grouped into three groups: factors of macro, meso and micro level. A comprehensive study of the factors determining the future development of innovation-active enterprises has been conducted in the article. It is shown that the effectiveness of the balanced development of innovation-active organizations in general, and the object of research , in particular , is determined by such factors as the structure and needs of the market , the resource base of innovative development , effective management system development, innovation activity . The authors believe that the inclusion of the multifaceted impact of factors will allow innovative active organizations to build a control system which allows more accurately predict the perspective direction of their future development.

  20. Presence in the pre-surgical fine-needle aspiration of potential thyroid biomarkers previously identified in the post-surgical one.

    Directory of Open Access Journals (Sweden)

    Federica Ciregia

    Full Text Available Fine-needle aspiration biopsy (FNA is usually applied to distinguish benign from malignant thyroid nodules. However, cytological analysis cannot always allow a proper diagnosis. We believe that the improvement of the diagnostic capability of pre-surgical FNA could avoid unnecessary thyroidectomy. In a previous study, we performed a proteome analysis to examine FNA collected after thyroidectomy. With the present study, we examined the applicability of these results on pre-surgical FNA. We collected pre-surgical FNA from 411 consecutive patients, and to obtain a correct comparison with our previous results, we processed only benign (n=114, papillary classical variant (cPTC (n=34 and papillary tall cell variant (TcPTC (n=14 FNA. We evaluated levels of five proteins previously found up-regulated in thyroid cancer with respect to benign nodules. ELISA and western blot (WB analysis were used to assay levels of L-lactate dehydrogenase B chain (LDHB, Ferritin heavy chain, Ferritin light chain, Annexin A1 (ANXA1, and Moesin in FNA. ELISA assays and WB analysis confirmed the increase of LDHB, Moesin, and ANXA1 in pre-surgical FNA of thyroid papillary cancer. Sensitivity and specificity of ANXA1 were respectively 87 and 94% for cPTC, 85 and 100% for TcPTC. In conclusion, a proteomic analysis of FNA from patients with thyroid nodules may help to distinguish benign versus malignant thyroid nodules. Moreover, ANXA1 appears to be an ideal candidate given the high sensitivity and specificity obtained from ROC curve analysis.

  1. Potential development in dye-sensitized solar cells for renewable energy

    CERN Document Server

    Pandikumar, Alagarsamy

    2013-01-01

    The development of photovoltaic technology is expected to solve problems related to energy shortages and environmental pollution caused by the use of fossil fuels. Dye-sensitizedsolar cells (DSSCs) are promising next-generation alternatives to conventional silicon-based photovoltaic devices owing to their low manufacturing cost and potentially high conversion efficiency. This special topic volume addresses recent advances in the research on dye-sensitized solar cells. The focus of this special topic volume is on materials development (sensitizers, nanostructured oxide films, and electrolyte),

  2. Modular femoral component for conversion of previous hip surgery in total hip arthroplasty.

    Science.gov (United States)

    Goldstein, Wayne M; Branson, Jill J

    2005-09-01

    The conversion of previous hip surgery to total hip arthroplasty creates a durable construct that is anatomically accurate. Most femoral components with either cemented or cementless design have a fixed tapered proximal shape. The proximal femoral anatomy is changed due to previous hip surgery for fixation of an intertrochanteric hip fracture, proximal femoral osteotomy, or a fibular allograft for avascular necrosis. The modular S-ROM (DePuy Orthopaedics Inc., Warsaw, Ind) hip stem accommodates these issues and independently prepares the proximal and distal portion of the femur. In preparation and implantation, the S-ROM hip stem creates less hoop stresses on potentially fragile stress risers from screws and thin bone. The S-ROM hip stem also prepares a previously distorted anatomy by milling through cortical bone that can occlude the femoral medullar canals and recreate proper femoral anteversion and reduces the risk of intraoperative or postoperative periprosthetic fracture due to the flexible titanium-slotted stem. The S-ROM femoral stem is recommended for challenging total hip reconstructions.

  3. Hepatic steatosis development with four weeks of physical inactivity in previously active, hyperphagic OLETF rats.

    Science.gov (United States)

    Linden, Melissa A; Meers, Grace M; Ruebel, Meghan L; Jenkins, Nathan T; Booth, Frank W; Laughlin, M Harold; Ibdah, Jamal A; Thyfault, John P; Rector, R Scott

    2013-05-01

    Physical activity-induced prevention of hepatic steatosis is maintained during short-term (7-day) transitions to an inactive state; however, whether these protective effects are present under a longer duration of physical inactivity is largely unknown. Here, we sought to determine whether previous physical activity had protective effects on hepatic steatosis and metabolic health following 4 wk of physical inactivity. Four-week old, hyperphagic, male Otsuka Long-Evans Tokushima fatty (OLETF) rats were randomly assigned to either a sedentary group for 16 wk (OLETF-SED), given access to running wheels for 16 wk with wheels locked 5 h (OLETF-WL5hr) or given access to running wheels for 12 wk with wheels locked 4 wk (OLETF-WL4wk) prior to death. Four weeks of physical inactivity caused hepatic steatosis development, but liver triglycerides remained 60% lower than OLETF-SED (P inactivity, whereas markers of fatty acid uptake and lipogenesis remained relatively suppressed following 4 wk of inactivity. In addition, 4 wk of inactivity caused a complete loss of activity-induced increases in serum IL-6 and reductions in regulated upon activation, normal T-cell expressed, and secreted (RANTES), and a partial loss in reductions in leptin, monocyte chemoattractant protein-1, and TNF-α. In conclusion, 4 wk of physical inactivity does not result in a complete loss in physical activity-induced benefits but does cause deterioration in the liver phenotype and overall metabolic health in hyperphagic OLETF rats.

  4. Fast Plasma Potential Measurements Using an Emissive Probe

    Science.gov (United States)

    Ready, Amanda; Clark, Michael; Endrizzi, Douglass; Forest, Cary; Peterson, Ethan

    2017-10-01

    A heated emissive probe was developed for making direct plasma potential (Vp) measurements in rapidly fluctuating plasmas. Previous experiments on the Big Red Ball (BRB) were hindered by sudden potential drops, making Langmuir measurements of the plasma potential difficult. DC heating of a tungsten filament to emission allowed for fast (4 MHz) floating potential measurements that closely matched Vp. Two BRB experiments currently use the emissive probe. The investigation of unmagnetized, collisionless shocks used plasma potential measurements to study the sub-structure of strong plasma shocks. A separate investigation of emulated magnetospheres in laboratory plasmas used the plasma potential to map the equilibria and instabilities in the electric field of such structures. Results showing electric field measurements and comparison with cold Langmuir measurements will be presented. Future plans for probe modifications and applications to other experiments on the BRB will also be shown.

  5. Potential role of nuclear power in developing and transition economies

    International Nuclear Information System (INIS)

    Ganiage, D.; Dierstein, P.

    1995-01-01

    The potential role of nuclear power is different in developing or in transition economies; in developing countries such as China, the growth of electricity consumption is high and the construction of several standardized plants is economically justified; in transitional economies, such as Ukraine, the needs are uncertain, old and unsafe plants have to be decommissioned and uncompleted nuclear plants (due to financial problems) should be completed. Nuclear power may provide the developing and transition economies with several advantages such as energy independence and fuel supply security, minimal environmental pollution, support to local industry and employment. It also means the support of national authorities and the development of a suitable infrastructure for plant safety and waste management, financial help and local population acceptance

  6. Previous bacterial infection affects textural quality parameters of heat-treated fillets from rainbow trout (Oncorhynchus mykiss)

    DEFF Research Database (Denmark)

    Ingerslev, Hans-Christian; Hyldig, Grethe; Przybylska, Dominika Alicja

    2012-01-01

    Sensory quality of fish meat is influenced by many parameters prior to slaughter. In the present study, it was examined if previous infections or damages in the muscle tissue influence product quality parameters in fish. Fillets from rainbow trout (Oncorhynchus mykiss) reared in seawater....... This article was the first to describe a correlation between previous infections in fish and changes in sensory-quality parameters. PRACTICAL APPLICATIONS. This work contributes with knowledge about sensory-quality parameters of fish meat after recovery from infections and physical-tissue damage. Because...... the results demonstrate an influence on the texture from previous disease, the practical potentials of the results are valuable for the aquaculture industry. In order to minimize the effects of previous diseases on the sensory quality regarding the texture, these fishes should be processed as cold...

  7. Boron neutron capture therapy (BNCT) inhibits tumor development from precancerous tissue: An experimental study that supports a potential new application of BNCT

    International Nuclear Information System (INIS)

    Monti Hughes, A.; Heber, E.M.; Pozzi, E.; Nigg, D.W.; Calzetta, O.; Blaumann, H.; Longhino, J.; Nievas, S.I.; Aromando, R.F.; Itoiz, M.E.; Trivillin, V.A.; Schwint, A.E.

    2009-01-01

    We previously demonstrated the efficacy of boron neutron capture therapy (BNCT) mediated by boronophenylalanine (BPA), GB-10 (Na 2 10 B 10 H 10 ) and (GB-10+BPA) to control tumors, with no normal tissue radiotoxicity, in the hamster cheek pouch oral cancer model. Herein we developed a novel experimental model of field-cancerization and precancerous lesions (globally termed herein precancerous tissue) in the hamster cheek pouch to explore the long-term potential inhibitory effect of the same BNCT protocols on the development of second primary tumors from precancerous tissue. Clinically, second primary tumor recurrences occur in field-cancerized tissue, causing therapeutic failure. We performed boron biodistribution studies followed by in vivo BNCT studies, with 8 months follow-up. All 3 BNCT protocols induced a statistically significant reduction in tumor development from precancerous tissue, reaching a maximum inhibition of 77-100%. The inhibitory effect of BPA-BNCT and (GB-10+BPA)-BNCT persisted at 51% at the end of follow-up (8 months), whereas for GB-10-BNCT it faded after 2 months. Likewise, beam-only elicited a significant but transient reduction in tumor development. No normal tissue radiotoxicity was observed. At 8 months post-treatment with BPA-BNCT or (GB-10+BPA)-BNCT, the precancerous pouches that did not develop tumors had regained the macroscopic and histological appearance of normal (non-cancerized) pouches. A potential new clinical application of BNCT would lie in its capacity to inhibit local regional recurrences.

  8. Boron neutron capture therapy (BNCT) inhibits tumor development from precancerous tissue: An experimental study that supports a potential new application of BNCT

    Energy Technology Data Exchange (ETDEWEB)

    Monti Hughes, A.; Heber, E.M. [Department of Radiobiology, National Atomic Energy Commission (CNEA), Buenos Aires (Argentina); Pozzi, E. [Department of Radiobiology, National Atomic Energy Commission (CNEA), Buenos Aires (Argentina); Department of Research and Production Reactors, Ezeiza Atomic Center, CNEA, Buenos Aires (Argentina); Nigg, D.W. [Idaho National Laboratory, Idaho Falls, Idaho (United States); Calzetta, O.; Blaumann, H.; Longhino, J. [Department of Nuclear Engineering, Bariloche Atomic Center, CNEA, Rio Negro (Argentina); Nievas, S.I. [Department of Chemistry, CNEA, Buenos Aires (Argentina); Aromando, R.F. [Department of Oral Pathology, Faculty of Dentistry, University of Buenos Aires, Buenos Aires (Argentina); Itoiz, M.E. [Department of Radiobiology, National Atomic Energy Commission (CNEA), Buenos Aires (Argentina); Department of Oral Pathology, Faculty of Dentistry, University of Buenos Aires, Buenos Aires (Argentina); Trivillin, V.A. [Department of Radiobiology, National Atomic Energy Commission (CNEA), Buenos Aires (Argentina); Schwint, A.E. [Department of Radiobiology, National Atomic Energy Commission (CNEA), Buenos Aires (Argentina)], E-mail: schwint@cnea.gov.ar

    2009-07-15

    We previously demonstrated the efficacy of boron neutron capture therapy (BNCT) mediated by boronophenylalanine (BPA), GB-10 (Na{sub 2}{sup 10}B{sub 10}H{sub 10}) and (GB-10+BPA) to control tumors, with no normal tissue radiotoxicity, in the hamster cheek pouch oral cancer model. Herein we developed a novel experimental model of field-cancerization and precancerous lesions (globally termed herein precancerous tissue) in the hamster cheek pouch to explore the long-term potential inhibitory effect of the same BNCT protocols on the development of second primary tumors from precancerous tissue. Clinically, second primary tumor recurrences occur in field-cancerized tissue, causing therapeutic failure. We performed boron biodistribution studies followed by in vivo BNCT studies, with 8 months follow-up. All 3 BNCT protocols induced a statistically significant reduction in tumor development from precancerous tissue, reaching a maximum inhibition of 77-100%. The inhibitory effect of BPA-BNCT and (GB-10+BPA)-BNCT persisted at 51% at the end of follow-up (8 months), whereas for GB-10-BNCT it faded after 2 months. Likewise, beam-only elicited a significant but transient reduction in tumor development. No normal tissue radiotoxicity was observed. At 8 months post-treatment with BPA-BNCT or (GB-10+BPA)-BNCT, the precancerous pouches that did not develop tumors had regained the macroscopic and histological appearance of normal (non-cancerized) pouches. A potential new clinical application of BNCT would lie in its capacity to inhibit local regional recurrences.

  9. Phytochemicals and Medicinal Properties of Indigenous Tropical Fruits with Potential for Commercial Development

    Directory of Open Access Journals (Sweden)

    Hock Eng Khoo

    2016-01-01

    Full Text Available Hundreds of fruit-bearing trees are native to Southeast Asia, but many of them are considered as indigenous or underutilized. These species can be categorized as indigenous tropical fruits with potential for commercial development and those possible for commercial development. Many of these fruits are considered as underutilized unless the commercialization is being realized despite the fact that they have the developmental potential. This review discusses seven indigenous tropical fruits from 15 species that have been identified, in which their fruits are having potential for commercial development. As they are not as popular as the commercially available fruits, limited information is found. This paper is the first initiative to provide information on the phytochemicals and potential medicinal uses of these fruits. Phytochemicals detected in these fruits are mainly the phenolic compounds, carotenoids, and other terpenoids. Most of these phytochemicals are potent antioxidants and have corresponded to the free radical scavenging activities and other biological activities of the fruits. The scientific research that covered a broad range of in vitro to in vivo studies on the medicinal potentials of these fruits is also discussed in detail. The current review is an update for researchers to have a better understanding of the species, which simultaneously can provide awareness to enhance their commercial value and promote their utilization for better biodiversity conservation.

  10. [Electronic cigarettes - effects on health. Previous reports].

    Science.gov (United States)

    Napierała, Marta; Kulza, Maksymilian; Wachowiak, Anna; Jabłecka, Katarzyna; Florek, Ewa

    2014-01-01

    Currently very popular in the market of tobacco products have gained electronic cigarettes (ang. E-cigarettes). These products are considered to be potentially less harmful in compared to traditional tobacco products. However, current reports indicate that the statements of the producers regarding to the composition of the e- liquids not always are sufficient, and consumers often do not have reliable information on the quality of the product used by them. This paper contain a review of previous reports on the composition of e-cigarettes and their impact on health. Most of the observed health effects was related to symptoms of the respiratory tract, mouth, throat, neurological complications and sensory organs. Particularly hazardous effects of the e-cigarettes were: pneumonia, congestive heart failure, confusion, convulsions, hypotension, aspiration pneumonia, face second-degree burns, blindness, chest pain and rapid heartbeat. In the literature there is no information relating to passive exposure by the aerosols released during e-cigarette smoking. Furthermore, the information regarding to the use of these products in the long term are not also available.

  11. Small Scaffolds, Big Potential: Developing Miniature Proteins as Therapeutic Agents.

    Science.gov (United States)

    Holub, Justin M

    2017-09-01

    Preclinical Research Miniature proteins are a class of oligopeptide characterized by their short sequence lengths and ability to adopt well-folded, three-dimensional structures. Because of their biomimetic nature and synthetic tractability, miniature proteins have been used to study a range of biochemical processes including fast protein folding, signal transduction, catalysis and molecular transport. Recently, miniature proteins have been gaining traction as potential therapeutic agents because their small size and ability to fold into defined tertiary structures facilitates their development as protein-based drugs. This research overview discusses emerging developments involving the use of miniature proteins as scaffolds to design novel therapeutics for the treatment and study of human disease. Specifically, this review will explore strategies to: (i) stabilize miniature protein tertiary structure; (ii) optimize biomolecular recognition by grafting functional epitopes onto miniature protein scaffolds; and (iii) enhance cytosolic delivery of miniature proteins through the use of cationic motifs that facilitate endosomal escape. These objectives are discussed not only to address challenges in developing effective miniature protein-based drugs, but also to highlight the tremendous potential miniature proteins hold for combating and understanding human disease. Drug Dev Res 78 : 268-282, 2017. © 2017 Wiley Periodicals, Inc. © 2017 Wiley Periodicals, Inc.

  12. Potential Development of Hydrocarbon in Basement Reservoirs In Indonesia

    Directory of Open Access Journals (Sweden)

    D. Sunarjanto

    2014-07-01

    Full Text Available DOI: 10.17014/ijog.v8i3.165Basement rocks, in particular igneous and metamorphic rocks are known to have porosity and permeability which should not be ignored. Primary porosity of basement rocks occurs as the result of rock formation. The porosity increases by the presence of cracks occurring as the result of tectonic processes (secondary porosity. Various efforts have been carried out to explore hydrocarbon in basement rocks. Some oil and gas fields proved that the basement rocks are as reservoirs which so far have provided oil and gas in significant amount. A review using previous research data, new data, and observation of igneous rocks in some fields has been done to see the development of exploration and basement reservoirs in Indonesia. A review on terminology of basement rock up till the identification of oil and gas exploration in basement rocks need to be based on the latest technology. An environmental approach is suggested to be applied as an alternative in analyzing the policy on oil and gas exploration development, especially in basement reservoirs.

  13. THE RESOURCE POTENTIAL AND THE DEVELOPMENT STRATEGY OF COMPETITIVE ADVANTAGES IN BUSINESS STRUCTURE

    Directory of Open Access Journals (Sweden)

    Ирина Юрьевна Окольнишникова

    2013-04-01

    Full Text Available The aim of the research is the development of theoretical approaches to the study of the essence and structure of the resource potential of entrepreneurship in the context of the development strategy of the competitive advantages in business structure.As the research methodology the complex of principles and tools of system and axiological approaches is used.According to the results of the conducted research, possessing the scientific novelty, the conceptual apparatus is clarified and the author's definition of the resource potential of the enterprise is given, a model of the resource potential structure in commercial organization is analyzed and the mechanism of strategy formation for sustainable competitive advantages provision of the organization on the basis of the effective use of its resource potential is identified.Area of application of the research results is the control of competitiveness in general and resource potential of entrepreneurial structures, in particular at all levels of the socio-economic system of society.DOI: http://dx.doi.org/10.12731/2218-7405-2013-2-39

  14. Development of genomic SSR and potential EST-SSR markers in ...

    African Journals Online (AJOL)

    In addition, forty four EST-SSRs which can be amplified with expected sizes were identified from a B. chinense root cDNA library. The genomic SSR markers and potential EST-SSR markers developed in the present study should be useful for genetic diversity and molecular marker assistant selection breeding research in ...

  15. Development of a Simple Tool for Identifying Alcohol Use Disorder in Female Korean Drinkers from Previous Questionnaires.

    Science.gov (United States)

    Seo, Yu Ri; Kim, Jong Sung; Kim, Sung Soo; Yoon, Seok Joon; Suh, Won Yoon; Youn, Kwangmi

    2016-01-01

    This study aimed to develop a simple tool for identifying alcohol use disorders in female Korean drinkers from previous questionnaires. This research was conducted on 400 women who consumed at least one alcoholic drink during the past month and visited the health promotion center at Chungnam National University Hospital between June 2013 to May 2014. Drinking habits and alcohol use disorders were assessed by structured interviews using the Diagnostic and Statistical Manual of Mental Disorders, 5th Edition diagnostic criteria. The subjects were also asked to answer the Alcohol Use Disorders Identification Test (AUDIT), AUDIT-Consumption, CAGE (Cut down, Annoyed, Guilty, Eye-opener), TWEAK (Tolerance, Worried, Eye-opener, Amnesia, Kut down), TACE (Tolerance, Annoyed, Cut down, Eye-opener), and NET (Normal drinker, Eye-opener, Tolerance) questionnaires. The area under receiver operating characteristic (AUROC) of each question of the questionnaires on alcohol use disorders was assessed. After combining two questions with the largest AUROC, it was compared to other previous questionnaires. Among the 400 subjects, 58 (14.5%) were identified as having an alcohol use disorder. Two questions with the largest AUROC were question no. 7 in AUDIT, "How often during the last year have you had a feeling of guilt or remorse after drinking?" and question no. 5 in AUDIT, "How often during the past year have you failed to do what was normally expected from you because of drinking?" with an AUROC (95% confidence interval [CI]) of 0.886 (0.850-0.915) and 0.862 (0.824-0.894), respectively. The AUROC (95% CI) of the combination of the two questions was 0.958 (0.934-0.976) with no significant difference as compared to the existing AUDIT with the largest AUROC. The above results suggest that the simple tool consisting of questions no. 5 and no. 7 in AUDIT is useful in identifying alcohol use disorders in Korean female drinkers.

  16. Characterization of previously unidentified lunar pyroclastic deposits using Lunar Reconnaissance Orbiter Camera (LROC) data

    Science.gov (United States)

    Gustafson, J. Olaf; Bell, James F.; Gaddis, Lisa R.R.; Hawke, B. Ray Ray; Giguere, Thomas A.

    2012-01-01

    We used a Lunar Reconnaissance Orbiter Camera (LROC) global monochrome Wide-angle Camera (WAC) mosaic to conduct a survey of the Moon to search for previously unidentified pyroclastic deposits. Promising locations were examined in detail using LROC multispectral WAC mosaics, high-resolution LROC Narrow Angle Camera (NAC) images, and Clementine multispectral (ultraviolet-visible or UVVIS) data. Out of 47 potential deposits chosen for closer examination, 12 were selected as probable newly identified pyroclastic deposits. Potential pyroclastic deposits were generally found in settings similar to previously identified deposits, including areas within or near mare deposits adjacent to highlands, within floor-fractured craters, and along fissures in mare deposits. However, a significant new finding is the discovery of localized pyroclastic deposits within floor-fractured craters Anderson E and F on the lunar farside, isolated from other known similar deposits. Our search confirms that most major regional and localized low-albedo pyroclastic deposits have been identified on the Moon down to ~100 m/pix resolution, and that additional newly identified deposits are likely to be either isolated small deposits or additional portions of discontinuous, patchy deposits.

  17. Clinical potential of boron neutron capture therapy for locally recurrent inoperable previously irradiated head and neck cancer

    International Nuclear Information System (INIS)

    Lim, Diana; Quah, Daniel SC; Leech, Michelle; Marignol, Laure

    2015-01-01

    This review compares the safety and efficacy of boron neutron capture therapy (BNCT) in the treatment of previously irradiated, inoperable locoregional recurrent HNC patients and compares BNCT against the standard treatment of platinum-based chemotherapy. Our analysis of published clinical trials highlights efficacy of BNCT associated with mild side effects. However, the use of BNCT should be explored in stratified randomised trials. - Highlights: • BNCT can prolong median overall survival. • BNCT can be associated with severe adverse effects. • BNCT may be comparable to chemotherapy-based regimens. • BNCT may be comparable to re-irradiation techniques regimens in patients with low performance status.

  18. Formation and development of hightechnology export corporate potential

    Directory of Open Access Journals (Sweden)

    Yevgen Panchenko

    2015-06-01

    Full Text Available This paper investigates the essence and peculiarities of high-Technology products exports in conditions of global competition with performed classification of its models on a corporate level. Peculiarities of corporate motivation of exporting high-technology products have been determined. Interconnection between innovation management system in transnational corporations and their capabilities of strengthening their competitive positions on world markets of high-technology products has been shown. Tendencies of fixing studies and developments during the last decade of leading companies, along with their influence on corporate innovative potential have been studied. On the example of aerospace sector of Ukraine, possibilities of strengthening the influence of high-technology export on rising of national economy international competitiveness have been determined. The need has been proved, and the ways have been shown for attraction of international investments into hightechnology sectors of Ukrainian economy through improvement of business conduct area, defense of intellectual property rights, and development of cooperation between national and transnational companies. Directions of use of integration factors of rising of volumes of export of high-technology Ukrainian products on the basis of developing cooperation of national enterprises with Russian partners have been shown.

  19. Cogeneration development and market potential in China

    Energy Technology Data Exchange (ETDEWEB)

    Yang, F.; Levine, M.D.; Naeb, J. [Lawrence Berkeley Lab., CA (United States); Xin, D. [State Planning Commission of China, Beijing, BJ (China). Energy Research Inst.

    1996-05-01

    China`s energy production is largely dependent on coal. China currently ranks third in global CO{sub 2} emissions, and rapid economic expansion is expected to raise emission levels even further in the coming decades. Cogeneration provides a cost-effective way of both utilizing limited energy resources and minimizing the environmental impacts from use of fossil fuels. However, in the last 10 years state investments for cogeneration projects in China have dropped by a factor of 4. This has prompted this study. Along with this in-depth analysis of China`s cogeneration policies and investment allocation is the speculation that advanced US technology and capital can assist in the continued growth of the cogeneration industry. This study provides the most current information available on cogeneration development and market potential in China.

  20. Potential protective effect of lactation against incidence of type 2 diabetes mellitus in women with previous gestational diabetes mellitus: A systematic review and meta-analysis.

    Science.gov (United States)

    Tanase-Nakao, Kanako; Arata, Naoko; Kawasaki, Maki; Yasuhi, Ichiro; Sone, Hirohito; Mori, Rintaro; Ota, Erika

    2017-05-01

    Lactation may protect women with previous gestational diabetes mellitus (GDM) from developing type 2 diabetes mellitus, but the results of existing studies are inconsistent, ranging from null to beneficial. We aimed to conduct a systematic review to gather available evidence. Databases MEDLINE, CINAHL, PubMed, and EMBASE were searched on December 15, 2015, without restriction of language or publication year. A manual search was also conducted. We included observational studies (cross-sectional, case-control, and cohort study) with information on lactation and type 2 diabetes mellitus incidence among women with previous GDM. We excluded case studies without control data. Data synthesis was conducted by random-effect meta-analysis. Fourteen reports of 9 studies were included. Overall risk of bias using RoBANS ranged from low to unclear. Longer lactation for more than 4 to 12 weeks postpartum had risk reduction of type 2 diabetes mellitus compared with shorter lactation (OR 0.77, 95% CI 0.01-55.86; OR 0.56, 95% CI 0.35-0.89; OR 0.22, 95% CI 0.13-0.36; type 2 diabetes mellitus evaluation time 5 y, respectively). Exclusive lactation for more than 6 to 9 weeks postpartum also had lower risk of type 2 diabetes mellitus compared with exclusive formula (OR 0.42, 95% CI 0.22-0.81). The findings support the evidence that longer and exclusive lactation may be beneficial for type 2 diabetes mellitus prevention in women with previous GDM. However, the evidence relies only on observational studies. Therefore, further studies are required to address the true causal effect. © 2017 The Authors. Diabetes/Metabolism Research and Reviews Published by John Wiley & Sons Ltd.

  1. Complication of cesarean section: pregnancy on the cicatrix of a previous cesarean section.

    Science.gov (United States)

    Wang, Weimin; Long, Wenqing; Yu, Qunhuan

    2002-02-01

    To probe into the clinical manifestation, diagnosis, as well as treatment of pregnancy on the cicatrix of a previous cesarean section at the uterine isthmus in the first trimester. Analysis of 14 patients with pregnancy on the cicatrix of a previous cesarean section at the uterine isthmus in the first trimester was made after conservative treatment by drugs from January 1996 to December 1999. The 14 patients with a pregnancy on the cicatrix of a previous cesarean section at the uterine isthmus in the first trimester were painless, had slight vaginal bleeding, and concurrently had increased serum beta-subunit human chorionic gonadotropin (beta-HCG). Doppler ultrasonic examination revealed an obvious enlargement of the previous cesarean section cicatrix in the uterine isthmus, and found a gestational sac or mixed mass attached to the cicatrice, with a very thin myometrium between the gestational sac and bladder walls. Among the 14 patients, 12 patients had crystalline trichosanthes injected into the cervix, mifepristone taken orally, or methotrexate in the form of intramuscular injection. Following this procedure, their serum beta-HCG dropped to normal. The other 2 patients had a total hysterectomy. Pregnancy on the cicatrix of a previous cesarean section at the uterine isthmus in the first trimester is a complication of cesarean section. Early diagnosis and effective conservative treatment by drugs are instrumental in decreasing the potential occurrence of uterine rupture, which is also conducive to preserving the patient's future fertility.

  2. A rare case of failed healing in previously burned skin after a secondary burns.

    Science.gov (United States)

    Goldie, Stephen J; Parsons, Shaun; Menezes, Hana; Ives, Andrew; Cleland, Heather

    2017-01-01

    Patients presenting with large surface area burns are common in our practice; however, patients with a secondary large burn on pre-existing burn scars and grafts are rare and not reported. We report on an unusual case of a patient sustaining a secondary large burn to areas previously injured by a burn from a different mechanism. We discuss the potential implications when managing a case like this and suggest potential biological reasons why the skin may behave differently. Our patient was a 33-year-old man who presented with a 5% TBSA burn on skin scarred by a previous 40% total body surface area (TBSA) burn and skin grafts. Initially assessed as superficial partial thickness in depth, the wounds were treated conservatively with dressings; however, they failed to heal and became infected requiring surgical management. Burns sustained in areas of previous burn scars and grafts may behave differently to normal patterns of healing, requiring more aggressive management and surgical intervention at an early stage.

  3. Development of Leadership Potential in Students within an Education Space of a Pedagogical University

    Science.gov (United States)

    Alimbekova, Anar; Asylbekova, Marziya; Karimova, Raziya

    2016-01-01

    In recent years in psychological and pedagogical sciences there is a trend for increase of interest in studies of students' potential in higher education institutions, because it is the major factor affecting development of student's inner potential. Majority of works in this field deal with the issues of study of student's personal potential,…

  4. Potential Development Essential Oil Production of Central Java, Indonesia

    Science.gov (United States)

    Alighiri, D.; Eden, W. T.; Supardi, K. I.; Masturi; Purwinarko, A.

    2017-04-01

    Indonesia is the source of raw essential oil in the world. Essential oils are used in various types of industries such as food and beverage, flavour, fragrance, perfumery, pharmaceuticals, and cosmetics. However, the development of Indonesian essential oil industry has not been encouraging for the production of essential oils, further it is unable to meet global demand. Besides that, the quality of volatile oil resulted cannot meet the international market standards. Based on the facts, the potential of Indonesian essential oils needs to be developed to provide added value, through increased production, improved quality and product diversification. One part of Indonesia having abundant of raw essential oil source is Central Java. Central Java has the quite large potential production of essential oils. Some essential oils produced from refining industry owned by the government, private and community sectors include cananga oils (Boyolali district), clove oils (Semarang district), patchouli oils (Brebes district, Pemalang district, and Klaten district). The main problem in the development of plants industries that producing essential oil in Central Java is low crops production, farming properties, quality of essential oils are diverse, providing poor-quality products and volatile oil price fluctuations. Marketing constraints of Central Java essential oils are quite complex supply chain. In general, marketing constraints of essential oils due to three factors, namely the low quality due to type of essential oil business that generally shaped small businesses with different capital and technology, domestic marketing is still a buyer-market (price determined by the buyer) because of weak bargaining position processors businessman, and prices fluctuate (domestic and foreign) due to uncontrolled domestic production and inter-country competition among manufacturers.

  5. Arts Integration as Potentiality for Professional Development for School Teachers

    DEFF Research Database (Denmark)

    Jensen, Julie Borup

    This paper investigates the potentialities for professional development, when teachers work with integration of arts and academic subjects in the classroom. The idea of integrating arts and academic subjects can be seen as a way of experimenting with teaching. Experiments in the classroom as a way...... of creating new knowledge about teaching is very closely linked to ideas from action research approaches to development of both new practices and new knowledge. Therefore, we will draw on concepts from action research theory to explore how teachers learn and at the same time develop new knowledge when......: Experience, Exploration, and Experimentation. In this way, the action research approach has the possibility of creating not only new practices, but also to develop new theoretic understanding of the learning processes involved in creating change in a living practice as classroom teaching. As an empirical...

  6. Perspective: the potential of student organizations for developing leadership: one school's experience.

    Science.gov (United States)

    Veronesi, Michael C; Gunderman, Richard B

    2012-02-01

    Leadership development is vital to the future of medicine. Some leadership development may take place through the formal curriculum of the medical school, yet extracurricular activities, such as student government and affiliated student organizations, can provide additional, highly valuable leadership development opportunities. These organizations and their missions can serve as catalysts for students to work with one another, with the faculty and administration of the medical school, with the community, and with local, regional, and national organizations. The authors have organized this discussion of the leadership development potential of student organizations around six important principles of leadership: ownership, experience, efficacy, sense of community, service learning, and peer-to-peer mentoring. They provide practical examples of these leadership principles from one institution. They do not presume that the school is unique, but they do believe their practical examples help to illuminate the potential of extracurricular programs for enhancing the leadership capabilities of future physicians. In addition, the authors use their examples to demonstrate how the medical school, its surrounding community, and the profession of medicine can benefit from promoting leadership through student organizations.

  7. Development of an identification system for potential ICES projects

    Energy Technology Data Exchange (ETDEWEB)

    None

    1978-11-01

    An earlier study by Real Estate Research Corporation (RERC) provides an overview of methods for developing marketing strategies for ICES. One aim of that document was to establish an information system for identifying areas, subareas, sites, or projects with substantial growth or development activity as potential candidates for the application of ICES. This report summarizes RERC's effort to implement and test such an information system. The specific objectives of this report are: (1) identify and collect basic information on 150 large-scale construction projects; (2) identify areas of the country, i.e., states and SMSAs that evidence general growth characteristics that would support ICES applications; (3) identify regions, states, and SMSAs that display higher-than-average energy costs; and (4) identify regions, states, and SMSAs that have experienced significant activity in identified land-use sectors and subsectors. Recent development activities in the commercial, industrial, residential, institutional, and transportation sectors are detailed. Mixed-use projects are included within the commercial sector. An annotated bibliography is included. (MCW)

  8. Development and potential applications of CRISPR-Cas9 genome editing technology in sarcoma.

    Science.gov (United States)

    Liu, Tang; Shen, Jacson K; Li, Zhihong; Choy, Edwin; Hornicek, Francis J; Duan, Zhenfeng

    2016-04-01

    Sarcomas include some of the most aggressive tumors and typically respond poorly to chemotherapy. In recent years, specific gene fusion/mutations and gene over-expression/activation have been shown to drive sarcoma pathogenesis and development. These emerging genomic alterations may provide targets for novel therapeutic strategies and have the potential to transform sarcoma patient care. The RNA-guided nuclease CRISPR-Cas9 (Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)-associated protein-9 nuclease) is a convenient and versatile platform for site-specific genome editing and epigenome targeted modulation. Given that sarcoma is believed to develop as a result of genetic alterations in mesenchymal progenitor/stem cells, CRISPR-Cas9 genome editing technologies hold extensive application potentials in sarcoma models and therapies. We review the development and mechanisms of the CRISPR-Cas9 system in genome editing and introduce its application in sarcoma research and potential therapy in clinic. Additionally, we propose future directions and discuss the challenges faced with these applications, providing concise and enlightening information for readers interested in this area. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

  9. Tetrahydroborates: Development and Potential as Hydrogen Storage Medium

    Directory of Open Access Journals (Sweden)

    Julián Puszkiel

    2017-10-01

    Full Text Available The use of fossil fuels as an energy supply becomes increasingly problematic from the point of view of both environmental emissions and energy sustainability. As an alternative, hydrogen is widely regarded as a key element for a potential energy solution. However, different from fossil fuels such as oil, gas, and coal, the production of hydrogen requires energy. Alternative and intermittent renewable sources such as solar power, wind power, etc., present multiple advantages for the production of hydrogen. On one hand, the renewable sources contribute to a remarkable reduction of pollutants released to the air. On the other hand, they significantly enhance the sustainability of energy supply. In addition, the storage of energy in form of hydrogen has a huge potential to balance an effective and synergetic utilization of the renewable energy sources. In this regard, hydrogen storage technology presents a key roadblock towards the practical application of hydrogen as “energy carrier”. Among the methods available to store hydrogen, solid-state storage is the most attractive alternative both from the safety and the volumetric energy density points of view. Because of their appealing hydrogen content, complex hydrides and complex hydride-based systems have attracted considerable attention as potential energy vectors for mobile and stationary applications. In this review, the progresses made over the last century on the development in the synthesis and research on the decomposition reactions of homoleptic tetrahydroborates is summarized. Furthermore, theoretical and experimental investigations on the thermodynamic and kinetic tuning of tetrahydroborates for hydrogen storage purposes are herein reviewed.

  10. Indicators of small town tourism development potential: the case of Fouriesburg, South Africa

    CSIR Research Space (South Africa)

    Halseth, G

    2009-05-01

    Full Text Available of Clarens has developed a substantial tourism economy, we pose the question of whether there are already indicators that Fouriesburg may be poised for similar change. The findings suggest that, while Fouriesburg has potential for developing a tourism...

  11. Development of Tools for Ensuring the Quality of Labor Potential of Industrial Enterprises

    Directory of Open Access Journals (Sweden)

    Ruslan Skrynkovskyy

    2017-09-01

    Full Text Available The purpose of the article is to deepen theoretical and methodological provisions and to develop tools for ensuring the quality of labor potential of industrial enterprises. It was established that the basis of the development of tools for quality assurance of labor potential (within the framework of the development of industrial enterprises lies the system of goals of managerial diagnostics of an industrial enterprise, which includes such key diagnostic objectives as: 1 diagnostics of the effectiveness of controlling the internal business processes of the enterprise; 2 diagnostics of the effectiveness of the typical organizational structure of enterprise management; 3 diagnostics of the efficiency of standardization of the work of linear and functional managers and specialists at the enterprise; 4 diagnostics of the enterprise in the areas of vocational education, labor activity and motivation, innovation work and social development; 5 diagnostics of management policies in the areas of social responsibility, information security and labor protection; 6 diagnostics of the level of conflict in the team at the enterprise 7 diagnosis of the effectiveness of the use of information technology in the management of the enterprise. It was determined that effective management of the quality of labor potential of the personnel (on the basis of its objective assessment is one of the key conditions that determines the success of industrial enterprises. The prospect of further research in this direction is improving the system of diagnostics and planning of reserves for improving the quality of labor potential of an industrial enterprise in crisis conditions.

  12. Harmonic development of tide-generating potential of terrestrial planets

    Science.gov (United States)

    Kudryavtsev, Sergey M.

    2008-08-01

    The aim of this study is to obtain high-accurate harmonic developments of the tide-generating potential (TGP) of Mercury, Venus and Mars. The planets’ TGP values have been first calculated on the base of DE/LE-406 numerical planetary/lunar ephemerides over a long period of time and then processed by a new spectral analysis method. According to this method the development is directly made to Poisson series where both amplitudes and arguments of the series’ terms are high-degree polynomials of time. A new harmonic development of Mars TGP is made over the time period 1900 AD 2100 AD and includes 767 second-order Poisson series’ terms of minimum amplitude equal to 10-7 m2 s-2. Analogous series composing both Mercury and Venus TGP harmonic models are built over the time period 1000 AD 3000 AD and include 1,061 and 693 terms, respectively. A modification of the standard HW95 format for representation of the terrestrial planets’ TGP is proposed. The number of terms in the planets’ TGP models transformed to the modified HW95 format is 650 for Mercury, 422 for Venus, and 480 for Mars. The quality of the new developments of the terrestrial planets’ TGP is better than that of the similar developments obtained earlier.

  13. Rambutan Commodity Development Strategy as Regional Potential Product

    Directory of Open Access Journals (Sweden)

    Amin Pujiati

    2016-06-01

    Full Text Available The potential product of a region needs to be developed in order to improve the social welfare. Commonly, at harvest time, there is abundant horticulture commodity. Unluckily, the price of the commodity drops significantly. In other words, it costs extremely cheap. The purpose of research is analyzing the internal and external factors and determining an appropriate strategy for developing rambutan in Central Java, especially at Gunungpati District, Semarang, Central Java Province. The primary data of this research is obtained from 58 rambutan farmers that have been interviewed and have filled out the questionnaire forms. The secondary data is taken from the Central Bureau of Statistics, the monograph of the village and the internet by implementing the literature study method. Then, SWOT analysis is implemented for analizing the data. The internal factors that become the strengths are fertilized land for rambutan to grow and the farmers’ hereditary experiences in cultivating rambutan. Further, the lack of absorbing power of knowledge and technologies and the low existence of rambutan business are the weaknesses. Next, the external factor that becomes opportunity is the continuous increasing market demand, while the threat is the young generations having no interest in rambutan business. Finally, the stability (hold and maintain strategy should be implemented for developing rambutan business

  14. Rambutan Commodity Development Strategy as Regional Potential Product

    Directory of Open Access Journals (Sweden)

    Amin Pujiati

    2016-06-01

    Full Text Available The potential product of a region needs to be developed in order to improve the social welfare. Commonly, at harvest time, there is abundant horticulture commodity. Unluckily, the price of the commodity drops significantly. In other words, it costs  extremely cheap. The purpose of research is analyzing the internal and external factors and determining an appropriate strategy for developing rambutan in Central Java, especially at Gunungpati District, Semarang, Central Java Province. The primary data of this research is obtained from 58 rambutan farmers that have been interviewed and have filled out the questionnaire forms. The secondary data is taken from the Central Bureau of Statistics, the monograph of the village and the internet by implementing the literature study method. Then, SWOT analysis is implemented for analizing the data. The internal factors that become the strengths are fertilized land for rambutan to grow and the farmers’ hereditary experiences in cultivating rambutan. Further, the lack of absorbing power of knowledge and technologies and the low existence of rambutan business are the weaknesses. Next, the external factor that becomes opportunity is the continuous increasing market demand, while the threat is the young generations having no interest in rambutan business. Finally, the stability (hold and maintain strategy should be implemented for developing rambutan business

  15. Case report of electronic cigarettes possibly associated with eosinophilic pneumonitis in a previously healthy active-duty sailor.

    Science.gov (United States)

    Thota, Darshan; Latham, Emi

    2014-07-01

    Electronic cigarettes (e-cigarettes) are a technology that has been touted as a safe and effective alternative to traditional cigarettes. There is, however, a paucity of literature showing the adverse outcomes of e-cigarettes and a correlation with acute eosinophilic pneumonia (AEP). To present a possible association between e-cigarettes and AEP. A 20-year-old previously healthy man was found to develop AEP after smoking an e-cigarette. He was treated with antibiotics and steroids and his symptoms improved. Though an alternative to traditional cigarettes, e-cigarettes can have unpredictable and potentially serious adverse effects. More research needs to be conducted to determine their safety. If seeing a patient in the ED with pulmonary symptoms after use of e-cigarettes, AEP should be considered in the differential. Published by Elsevier Inc.

  16. Calcium-Induced calcium release during action potential firing in developing inner hair cells.

    Science.gov (United States)

    Iosub, Radu; Avitabile, Daniele; Grant, Lisa; Tsaneva-Atanasova, Krasimira; Kennedy, Helen J

    2015-03-10

    In the mature auditory system, inner hair cells (IHCs) convert sound-induced vibrations into electrical signals that are relayed to the central nervous system via auditory afferents. Before the cochlea can respond to normal sound levels, developing IHCs fire calcium-based action potentials that disappear close to the onset of hearing. Action potential firing triggers transmitter release from the immature IHC that in turn generates experience-independent firing in auditory neurons. These early signaling events are thought to be essential for the organization and development of the auditory system and hair cells. A critical component of the action potential is the rise in intracellular calcium that activates both small conductance potassium channels essential during membrane repolarization, and triggers transmitter release from the cell. Whether this calcium signal is generated by calcium influx or requires calcium-induced calcium release (CICR) is not yet known. IHCs can generate CICR, but to date its physiological role has remained unclear. Here, we used high and low concentrations of ryanodine to block or enhance CICR to determine whether calcium release from intracellular stores affected action potential waveform, interspike interval, or changes in membrane capacitance during development of mouse IHCs. Blocking CICR resulted in mixed action potential waveforms with both brief and prolonged oscillations in membrane potential and intracellular calcium. This mixed behavior is captured well by our mathematical model of IHC electrical activity. We perform two-parameter bifurcation analysis of the model that predicts the dependence of IHCs firing patterns on the level of activation of two parameters, the SK2 channels activation and CICR rate. Our data show that CICR forms an important component of the calcium signal that shapes action potentials and regulates firing patterns, but is not involved directly in triggering exocytosis. These data provide important insights

  17. Formation of the controlling mechanism in the management of innovative development of enterprise potential

    Directory of Open Access Journals (Sweden)

    Андрій Анатолійович Пилипенко

    2015-11-01

    Full Text Available The article presents the guidelines for the formation of the controlling mechanism in the activation cycles of innovative activities and the formation of the development programs of the enterprise potential. It is offered understanding the development potential and proved grouping of controlled performance, taking into account the level of innovation ability of the enterprise. It is presented the strategic matrix of determining the composition of performance, determination of monitoring parameters and aspects of controlling mechanism

  18. The limits and potential of community development for personal and social change.

    Science.gov (United States)

    Dixon, J

    1989-01-01

    Some health and welfare workers are making claims for community development which are both unrealistic and misleading. By tracing the history and public policy use of community development and by defining its characteristics, much of the mystique which surrounds this intervention is eliminated. Community development is revealed in this paper to have potential in the areas of personal and planned social change. However, community development's contribution to fundamental social change is circumscribed by the nature of government sponsorship and by its very process which emphasizes parochialism and the generation of self reliance.

  19. Potential for Jobs and Economic Development from Offshore Wind in California

    Energy Technology Data Exchange (ETDEWEB)

    Tegen, Suzanne

    2016-11-02

    In California's future scenarios, energy demand increases with population growth and productivity. Decision-makers will have to make choices about which energy resources to utilize, and offshore wind offers one option for carbon-free electricity with the potential for increased local jobs. This presentation discusses results from an NREL report, Floating Offshore Wind in California: Gross Potential for Jobs and Economic Impacts from Two Future Scenarios. Presenter Suzanne Tegen describes the Jobs and Economic Development Impact (JEDI) model and its results for two offshore wind scenarios in California. She discusses different assumptions and how they affect the scenarios.

  20. Developments and potential of radiation processing in the Philippines

    Energy Technology Data Exchange (ETDEWEB)

    Singson, C; Carmona, C [Philippine Atomic Energy Commission, Diliman, Quezon City

    1981-01-01

    This paper describes the research and development activities in three areas of radiation processing, namely: food irradiation, medical product sterilization and wood plastic combination. Plans and efforts exerted to acquire a larger gamma source to augment our present 5,000 curie source are discussed. Cost estimates for a radiation facility are presented on the basis of the market potential of food irradiation and medical product sterilization. Existing local industries that can benefit from the adaptation of irradiation technology in their processing requirements are described.

  1. ICTs for rural development: potential applications and barriers involved

    Directory of Open Access Journals (Sweden)

    Anastasia Stratigea

    2013-03-01

    Full Text Available Rural policy nowadays is at the heart of the policy discussion in many countries all over the world, in the effort to address and effectively support the specific needs and opportunities of rural places and their population in the new era. Along these lines, the focus of the present paper is twofold: on the one hand it attempts to shed light on the role of ICTs and their applications as enabling tools empowering rural development; while on the other hand it explores the barriers appearing towards the adoption and use of ICTs in rural regions. In such a context, it firstly places emphasis on the evolving new rural development paradigm. Then, the range and potential of ICTs applications is explored, that can serve the implementation of the new policy paradigm in rural regions. It follows a discussion on the steps that are needed in order to develop value-added ICTs applications in rural regions and the barriers appearing in the adoption and use of ICTs in these regions. Finally, are presented some issues of policy concern in respect to the adoption and use of ICTs in a rural development perspective.

  2. Development of molecular dynamics potential for uranium silicide fuels

    Energy Technology Data Exchange (ETDEWEB)

    Yu, Jianguo; Zhang, Yongfeng; Hales, Jason D.

    2016-09-01

    Use of uranium–silicide (U-Si) in place of uranium dioxide (UO2) is one of the promising concepts being proposed to increase the accident tolerance of nuclear fuels. This is due to a higher thermal conductivity than UO2 that results in lower centerline temperatures. U-Si also has a higher fissile density, which may enable some new cladding concepts that would otherwise require increased enrichment limits to compensate for their neutronic penalty. However, many critical material properties for U-Si have not been determined experimentally. For example, silicide compounds (U3Si2 and U3Si) are known to become amorphous under irradiation. There was clear independent experimental evidence to support a crystalline to amorphous transformation in those compounds. However, it is still not well understood how the amorphous transformation will affect on fuel behavior. It is anticipated that modeling and simulation may deliver guidance on the importance of various properties and help prioritize experimental work. In order to develop knowledge-based models for use at the engineering scale with a minimum of empirical parameters and increase the predictive capabilities of the developed model, inputs from atomistic simulations are essential. First-principles based density functional theory (DFT) calculations will provide the most reliable information. However, it is probably not possible to obtain kinetic information such as amorphization under irradiation directly from DFT simulations due to size and time limitations. Thus, a more feasible way may be to employ molecular dynamics (MD) simulation. Unfortunately, so far no MD potential is available for U-Si to discover the underlying mechanisms. Here, we will present our recent progress in developing a U-Si potential from ab initio data. This work is supported by the Nuclear Energy Advanced Modeling and Simulation (NEAMS) program funded by the U.S. Department of Energy, Office of Nuclear Energy.

  3. The potential impacts of sodium management on Frit Development for Coupled Operations

    Energy Technology Data Exchange (ETDEWEB)

    Johnson, F. C. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL); Edwards, T. B. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL); Peeler, D. K. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL)

    2015-06-10

    In this report, Section 2.0 provides a description of sodium management and its impact on the glass waste form, Section 3.0 provides background information on phase separation, Section 4.0 provides the impact of sodium management on SB9 frit development efforts and the results of a limited scoping study investigating phase separation in potential DWPF frits, and Section 5.0 discusses potential technical issues associated with using a phase separated frit for DWPF operations.

  4. Development and validation of SUCROS-Cotton : A potential crop growth simulation model for cotton

    NARCIS (Netherlands)

    Zhang, L.; Werf, van der W.; Cao, W.; Li, B.; Pan, X.; Spiertz, J.H.J.

    2008-01-01

    A model for the development, growth and potential production of cotton (SUCROS-Cotton) was developed. Particular attention was given to the phenological development of the plant and the plasticity of fruit growth in response to temperature, radiation, daylength, variety traits, and management. The

  5. Antimetabolites in cataract surgery to prevent failure of a previous trabeculectomy.

    Science.gov (United States)

    Thomas, Roger E; Crichton, Andrew; Thomas, Bennett C

    2014-07-28

    Patients having cataract surgery have often earlier undergone a trabeculectomy for glaucoma. However, cataract surgery may be associated with failure of the previous glaucoma surgery and antimetabolites may be used with cataract surgery to prevent such failure. There is no systematic review on whether antimetabolites with cataract surgery prevent failure of a previous trabeculectomy. To assess the effects of antimetabolites with cataract surgery on functioning of a previous trabeculectomy. We searched CENTRAL (which contains the Cochrane Eyes and Vision Group Trials Register) (2014, Issue 5), Ovid MEDLINE, Ovid MEDLINE In-Process and Other Non-Indexed Citations, Ovid MEDLINE Daily, Ovid OLDMEDLINE (January 1946 to June 2014), EMBASE (January 1980 to June 2014), Latin American and Caribbean Health Sciences Literature Database (LILACS) (January 1982 to June 2014), the metaRegister of Controlled Trials (mRCT) (www.controlled-trials.com), ClinicalTrials.gov (www.clinicaltrials.gov) and the World Health Organization (WHO) International Clinical Trials Registry Platform (ICTRP) (www.who.int/ictrp/search/en). We did not use any date or language restrictions in the electronic searches for trials. We last searched the electronic databases on 10 June 2014. We also searched the Science Citation Index database (July 2013) and reference lists of potentially relevant studies. Randomised controlled trials (RCTs) of antimetabolites with cataract surgery in people with a functioning trabeculectomy. Two review authors independently reviewed the titles and abstracts from the electronic searches. Two review authors independently assessed relevant full-text articles and entered data. We identified no RCTs to test the effectiveness of antimetabolites with cataract surgery in individuals with the intention of preventing failure of a previous trabeculectomy. There are no RCTs of antimetabolites with cataract surgery in people with a functioning trabeculectomy. Appropriately powered RCTs

  6. The Resource Structure of the Potential of Economic Development and Growth of Wealth of the Modern Macroeconomic Systems

    Directory of Open Access Journals (Sweden)

    Silantiev Oleh I.

    2018-03-01

    Full Text Available The publication is aimed at researching the features of formation and structure of economic potential of the economic development of modern macroeconomic systems. The research used the structural-functional, systemic, integral and logical approaches together with the methods of analysis and synthesis, induction and deduction. A formalization of the resource structure of the potential of economic development of modern macroeconomic systems with allocation of defining (mandatory kinds of resources (wealth and clarification of their (its specifics in the concrete historical conditions of society’s living was carried out. The bases of identification of essence and structure of the economic potential of development of the modern macroeconomic systems are clarified by its kinds. The factors of strategic influence on the process of formation of the economic development potential of the modern macroeconomic systems were researched. The value of the carried out research is the improved theoretical approaches to understanding the essence and structure of both the economic potential and the economic development potential of macroeconomic systems. Prospects for further research are the in-depth analysis of the individual components of the resource structure of the economic development potential of macroeconomic systems, especially the imperative types of wealth.

  7. Delayed vaginal reconstruction in the fibrotic pelvis following radiation or previous reconstruction

    International Nuclear Information System (INIS)

    Berek, J.S.; Hacker, N.F.; Lagasse, L.D.; Smith, M.L.

    1983-01-01

    Vaginal reconstruction was performed in 14 patients who had developed vaginal stenosis secondary to extensive pelvic fibrosis after pelvic radiation therapy (12 patients) or prior vaginal reconstruction (2 patients). Sixteen procedures were performed using a split-thickness skin graft. All patients had satisfactory vaginal restoration, and 12 patients reported good vaginal function. No fistula developed as a result of the operative procedure, but one patient later developed a rectovaginal fistula resulting from tumor recurrence. Successful vaginal reconstruction can be achieved even years after initial therapy in patients who develop an obliterated vagina from previous radiation or surgery

  8. Planning policy, sustainability and housebuilder practices: The move into (and out of?) the redevelopment of previously developed land.

    Science.gov (United States)

    Karadimitriou, Nikos

    2013-05-01

    This paper explores the transformations of the housebuilding industry under the policy requirement to build on previously developed land (PDL). This requirement was a key lever in promoting the sustainable urban development agenda of UK governments from the early 1990s to 2010 and has survived albeit somewhat relaxed and permutated in the latest National Planning Policy Framework (NPPF). The paper therefore looks at the way in which the policy push towards densification and mixed use affected housebuilders' business strategy and practices and their ability to cope with the 2007 downturn of the housing market and its aftermath. It also points out the eventual feedback of some of these practices into planning policy. Following the gradual shift of British urban policy focus towards sustainability which started in the early 1990s, new configurations of actors, new skills, strategies and approaches to managing risk emerged in property development and housebuilding. There were at least two ways in which housebuilders could have responded to the requirements of developing long term mixed use high density projects on PDL. One way was to develop new products and to employ practices and combinations of practices involving phasing, a flexible approach to planning applications and innovative production methods. Alternatively, they could approach PDL development as a temporary turn of policy or view mixed use high density schemes as a niche market to be explored without drastically overhauling the business model of the entire firm. These transformations of the UK housebuilding sector were unfolding during a long period of buoyancy in the housing market which came to an end in 2007. Very little is known both about how housebuilder strategies and production practices evolved during the boom years as well as about how these firms coped with the effects of the 2007 market downturn. The paper draws on published data (company annual reports, government statistics) and primary

  9. Planning policy, sustainability and housebuilder practices: The move into (and out of?) the redevelopment of previously developed land

    Science.gov (United States)

    Karadimitriou, Nikos

    2013-01-01

    This paper explores the transformations of the housebuilding industry under the policy requirement to build on previously developed land (PDL). This requirement was a key lever in promoting the sustainable urban development agenda of UK governments from the early 1990s to 2010 and has survived albeit somewhat relaxed and permutated in the latest National Planning Policy Framework (NPPF). The paper therefore looks at the way in which the policy push towards densification and mixed use affected housebuilders’ business strategy and practices and their ability to cope with the 2007 downturn of the housing market and its aftermath. It also points out the eventual feedback of some of these practices into planning policy. Following the gradual shift of British urban policy focus towards sustainability which started in the early 1990s, new configurations of actors, new skills, strategies and approaches to managing risk emerged in property development and housebuilding. There were at least two ways in which housebuilders could have responded to the requirements of developing long term mixed use high density projects on PDL. One way was to develop new products and to employ practices and combinations of practices involving phasing, a flexible approach to planning applications and innovative production methods. Alternatively, they could approach PDL development as a temporary turn of policy or view mixed use high density schemes as a niche market to be explored without drastically overhauling the business model of the entire firm. These transformations of the UK housebuilding sector were unfolding during a long period of buoyancy in the housing market which came to an end in 2007. Very little is known both about how housebuilder strategies and production practices evolved during the boom years as well as about how these firms coped with the effects of the 2007 market downturn. The paper draws on published data (company annual reports, government statistics) and primary

  10. A review on the potential of aquaculture development in Kenya for ...

    African Journals Online (AJOL)

    A review on the potential of aquaculture development in Kenya for poverty alleviation and food security. ... It is estimated that another 40 million metric tonnes of aquatic food will be required by the year 2030. Today ... Key words: Fish production, capture fisheries, culture systems, Economic Stimulus Programme, aquaculture ...

  11. The association between previous and future severe exacerbations of chronic obstructive pulmonary disease: Updating the literature using robust statistical methodology.

    Science.gov (United States)

    Sadatsafavi, Mohsen; Xie, Hui; Etminan, Mahyar; Johnson, Kate; FitzGerald, J Mark

    2018-01-01

    There is minimal evidence on the extent to which the occurrence of a severe acute exacerbation of COPD that results in hospitalization affects the subsequent disease course. Previous studies on this topic did not generate causally-interpretable estimates. Our aim was to use corrected methodology to update previously reported estimates of the associations between previous and future exacerbations in these patients. Using administrative health data in British Columbia, Canada (1997-2012), we constructed a cohort of patients with at least one severe exacerbation, defined as an episode of inpatient care with the main diagnosis of COPD based on international classification of diseases (ICD) codes. We applied a random-effects 'joint frailty' survival model that is particularly developed for the analysis of recurrent events in the presence of competing risk of death and heterogeneity among individuals in their rate of events. Previous severe exacerbations entered the model as dummy-coded time-dependent covariates, and the model was adjusted for several observable patient and disease characteristics. 35,994 individuals (mean age at baseline 73.7, 49.8% female, average follow-up 3.21 years) contributed 34,271 severe exacerbations during follow-up. The first event was associated with a hazard ratio (HR) of 1.75 (95%CI 1.69-1.82) for the risk of future severe exacerbations. This risk decreased to HR = 1.36 (95%CI 1.30-1.42) for the second event and to 1.18 (95%CI 1.12-1.25) for the third event. The first two severe exacerbations that occurred during follow-up were also significantly associated with increased risk of all-cause mortality. There was substantial heterogeneity in the individual-specific rate of severe exacerbations. Even after adjusting for observable characteristics, individuals in the 97.5th percentile of exacerbation rate had 5.6 times higher rate of severe exacerbations than those in the 2.5th percentile. Using robust statistical methodology that controlled

  12. Bioenergy development pathways for Europe. Potentials, costs and environmental impacts

    Energy Technology Data Exchange (ETDEWEB)

    De Wit, M.P.

    2011-09-26

    Fossil resources dominate the global energy system today which cannot be sustained indefinitely. Bioenergy use can meet a large share of future energy supply sustainably. For example, it can substitute fossil fuels including petroleum, and when sustainably produced, bioenergy avoids greenhouse gas emissions. However, with the recent increase of modern bioenergy use several drawbacks have become apparent that may lead to negative ecological impacts. Europe plays an important role in the further sustainable development of bioenergy due to its ambitious renewable energy policies and its state-of-the-art agricultural sector. The main objective of this thesis is to evaluate development pathways for bioenergy in Europe by assessing preconditions for its development, an economic outlook for such development and an assessment of its environmental implications. The technical European biomass potential has a substantial potential to contribute to Europe's energy consumption. Energy crop production on European croplands and grasslands supplemented with agricultural and forestry residues offers an ultimate technical potential of 27.7 EJ y-1. These findings were based on the assumption that agricultural land needs for future domestic food production decrease as productivities per hectare increase. Central and Eastern Europe pose the more attractive region with relatively high potentials and low costs. In European agriculture, it is possible to combine large-scale biomass production with food production sustained at current levels, without direct or indirect land-use changes and while accomplishing significant net cumulative greenhouse gas emission reductions when both bioenergy and agricultural production are considered. To accomplish this situation two preconditions need to be met: a gradual intensification of food production and implementation of structural improvements to agricultural management. Based on the current economic performance and future prospects for

  13. KEY DEVELOPMENT FACTORS OF THE TRANSIT AND TRANSPORT POTENTIAL OF KAZAKHSTAN

    Directory of Open Access Journals (Sweden)

    Seidulla ABDULLAYEV

    2016-06-01

    Full Text Available Nowadays, the Republic of Kazakhstan is dynamically forming up its transit policy, improving its directions and the development of new vectors. This article looks into the development of the transit and transport potential of the Republic of Kazakhstan. It presents the main conclusions on the development of a feasibility study for the construction of a logistics terminal in the seaport of Lianyungang (China as one of the directions of building transit policy, improving its direction and the formation of new vectors. The urgency of building a logistics terminal is conditioned by the necessity for national interests and further expansion of political and economic advantages of Kazakhstan.

  14. 49 CFR 173.23 - Previously authorized packaging.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 2 2010-10-01 2010-10-01 false Previously authorized packaging. 173.23 Section... REQUIREMENTS FOR SHIPMENTS AND PACKAGINGS Preparation of Hazardous Materials for Transportation § 173.23 Previously authorized packaging. (a) When the regulations specify a packaging with a specification marking...

  15. 22 CFR 40.91 - Certain aliens previously removed.

    Science.gov (United States)

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Certain aliens previously removed. 40.91... IMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Aliens Previously Removed § 40.91 Certain aliens previously removed. (a) 5-year bar. An alien who has been found inadmissible, whether as a result...

  16. TOURISTIC POTENTIAL, MANAGEMENT AND DEVELOPMENT IN THE RARĂU MASSIF

    Directory of Open Access Journals (Sweden)

    Dinu OPREA-GANCEVICI

    2011-06-01

    Full Text Available As a socio-economic activity, tourism is strongly influenced by numerous factors that determine the size and direction of tourist flows. Mountain tourism is no exception; the mountainous land relief, which generates this type of tourism, possesses a large array of factors which, by definition, represent true attractions for tourists (morphometric elements, types and landforms, oxygen-rich air, specific flora and fauna, but also several factors that may inhibit tourist activity proper (development capacity, climate, natural phenomena hazards.In particular, with reference to the Rarău Massif, we shall emphasize its tourist potential, especially the geomorphologic one, but we shall also highlight the evolution and the present state of infrastructure (accommodation facilities, tourist paths. The cartographic analysis and representation were obtained using dedicated software, generically called Geographic Informatics Systems (GIS, and a social research method as well – the questionnaire. As such, our research features several maps that highlight the differentiated land relief potential as well as the potential resulted from the application of questionnaires, thus bringing into the foreground the areas with maximal morphologic attractiveness and implicitly potential for tourist activity. In order to make the most of the entire massif and to diversify tourist routes we propose new itineraries with a view to covering the entire area more effectively and offering new exploration variants for the massif. The applied questionnaire proves the connection between the tourist potential of land relief and tourists’ perceptions of the tourist sights in the Rarău Massif.

  17. Development of a portable blood irradiator for potential clinical uses

    Energy Technology Data Exchange (ETDEWEB)

    Hungate, F.P.

    1988-12-01

    This document provides an account of the development of a fully portable blood irradiator and the evaluation of its safety and efficacy when implanted in goats, sheep, a baboon and dogs. The program was initiated because the control of lymphocyte populations by irradiation is a potential method for improving success in organ or tissue transplantation and for treating a variety of blood diseases. 15 refs., 27 figs., 2 tabs.

  18. Potential Market for Satellite Technology in Meeting Telecommunication Needs of Developing Nations

    Science.gov (United States)

    1996-01-01

    A recent study examined the potential for satellite technology to meet the telecommunication needs of developing nations. The growth of these nations depends on their attracting and holding the industrial investments of developed nations. This will not be likely with the antiquated telecommunications infrastructure typical of developing nations. On the contrary, it will require an infrastructure that is compatible with international standards. Most of the developing nations perceive this necessity and are pursuing the necessary upgrades. The rate of replacement, types of technology, services affected, and the terrestrial/satellite mix differ by each nation's priorities and gross national product (GNP).

  19. Previous experience in manned space flight: A survey of human factors lessons learned

    Science.gov (United States)

    Chandlee, George O.; Woolford, Barbara

    1993-01-01

    Previous experience in manned space flight programs can be used to compile a data base of human factors lessons learned for the purpose of developing aids in the future design of inhabited spacecraft. The objectives are to gather information available from relevant sources, to develop a taxonomy of human factors data, and to produce a data base that can be used in the future for those people involved in the design of manned spacecraft operations. A study is currently underway at the Johnson Space Center with the objective of compiling, classifying, and summarizing relevant human factors data bearing on the lessons learned from previous manned space flights. The research reported defines sources of data, methods for collection, and proposes a classification for human factors data that may be a model for other human factors disciplines.

  20. Global warming potential of pavements

    Energy Technology Data Exchange (ETDEWEB)

    Santero, Nicholas J [Department of Civil and Environmental Engineering, 407 McLaughlin Hall, University of California, Berkeley, CA 94720-1712 (United States); Horvath, Arpad, E-mail: njsantero@cal.berkeley.ed, E-mail: horvath@ce.berkeley.ed [Department of Civil and Environmental Engineering, 215B McLaughlin Hall, University of California, Berkeley, CA 94720-1712 (United States)

    2009-09-15

    Pavements comprise an essential and vast infrastructure system supporting our transportation network, yet their impact on the environment is largely unquantified. Previous life-cycle assessments have only included a limited number of the applicable life-cycle components in their analysis. This research expands the current view to include eight different components: materials extraction and production, transportation, onsite equipment, traffic delay, carbonation, lighting, albedo, and rolling resistance. Using global warming potential as the environmental indicator, ranges of potential impact for each component are calculated and compared based on the information uncovered in the existing research. The relative impacts between components are found to be orders of magnitude different in some cases. Context-related factors, such as traffic level and location, are also important elements affecting the impacts of a given component. A strategic method for lowering the global warming potential of a pavement is developed based on the concept that environmental performance is improved most effectively by focusing on components with high impact potentials. This system takes advantage of the fact that small changes in high-impact components will have more effect than large changes in low-impact components.

  1. Global warming potential of pavements

    International Nuclear Information System (INIS)

    Santero, Nicholas J; Horvath, Arpad

    2009-01-01

    Pavements comprise an essential and vast infrastructure system supporting our transportation network, yet their impact on the environment is largely unquantified. Previous life-cycle assessments have only included a limited number of the applicable life-cycle components in their analysis. This research expands the current view to include eight different components: materials extraction and production, transportation, onsite equipment, traffic delay, carbonation, lighting, albedo, and rolling resistance. Using global warming potential as the environmental indicator, ranges of potential impact for each component are calculated and compared based on the information uncovered in the existing research. The relative impacts between components are found to be orders of magnitude different in some cases. Context-related factors, such as traffic level and location, are also important elements affecting the impacts of a given component. A strategic method for lowering the global warming potential of a pavement is developed based on the concept that environmental performance is improved most effectively by focusing on components with high impact potentials. This system takes advantage of the fact that small changes in high-impact components will have more effect than large changes in low-impact components.

  2. CO2 emissions mitigation potential of solar home systems under clean development mechanism in India

    International Nuclear Information System (INIS)

    Purohit, Pallav

    2009-01-01

    The Government of India has taken several initiatives for promotion of solar energy systems in the country during the last two decades. A variety of policy measures have been adopted which include provision of financial and fiscal incentives to the potential users of solar energy systems however, only 0.4 million solar home systems (SHSs) have been installed so far that is far below their respective potential. One of the major barriers is the high costs of investments in these systems. The clean development mechanism (CDM) of the Kyoto Protocol provides industrialized (Annex-I) countries with an incentive to invest in emission reduction projects in developing (non-Annex-I) countries to achieve a reduction in carbon dioxide (CO 2 ) emissions at lowest cost that also promotes sustainable development in the host country. SHSs could be of interest under the CDM because they directly displace greenhouse gas (GHG) emissions while contributing to sustainable rural development, if developed correctly. In this study an attempt has been made to estimate the CO 2 mitigation potential of SHSs under CDM in India.

  3. The relationship between cerebrovascular complications and previously established use of antiplatelet therapy in left-sided infective endocarditis

    DEFF Research Database (Denmark)

    Snygg-Martin, Ulrika; Rasmussen, Rasmus Vedby; Hassager, Christian

    2011-01-01

    Cerebrovascular complications (CVC) in infective endocarditis (IE) are common. The only established treatments to reduce the incidence of CVC in IE are antibiotics and in selected cases early cardiac surgery. Potential effects of previously established antiplatelet therapy are under debate....

  4. Potential Bioenergy Options in Developed and Developing Countries

    African Journals Online (AJOL)

    Plant –based energy production (energy crops, forest growth) and residue and waste based fuels can substitute fossil fuels in a sustainable and environmental friendly way. In this study, bioenergy includes bio-resources that can be potentially used for modern energy production. Modern bioenergy options offer significant, ...

  5. How to prevent type 2 diabetes in women with previous gestational diabetes?

    DEFF Research Database (Denmark)

    Pedersen, Anne Louise Winkler; Terkildsen Maindal, Helle; Juul, Lise

    2017-01-01

    OBJECTIVES: Women with previous gestational diabetes (GDM) have a seven times higher risk of developing type 2 diabetes (T2DM) than women without. We aimed to review the evidence of effective behavioural interventions seeking to prevent T2DM in this high-risk group. METHODS: A systematic review...... of RCTs in several databases in March 2016. RESULTS: No specific intervention or intervention components were found superior. The pooled effect on diabetes incidence (four trials) was estimated to: -5.02 per 100 (95% CI: -9.24; -0.80). CONCLUSIONS: This study indicates that intervention is superior...... to no intervention in prevention of T2DM among women with previous GDM....

  6. Potential of Sugarcane in Modern Energy Development in Southern Africa

    Energy Technology Data Exchange (ETDEWEB)

    Souza, Simone P., E-mail: sp.souza@yahoo.com.br; Horta Nogueira, Luiz A. [Interdisciplinary Center for Energy Planning, University of Campinas (UNICAMP), Campinas, SP (Brazil); Watson, Helen K. [School of Agricultural, Earth and Environmental Sciences, University of KwaZulu-Natal, Durban, KZN (South Africa); Lynd, Lee Rybeck [Dartmouth College, Thayer School of Engineering, Dartmouth, NH (United States); Elmissiry, Mosad [New Partnership for Africa’s Development (NEPAD), Johannesburg, GT (South Africa); Cortez, Luís A. B. [Faculty of Agricultural Engineering, University of Campinas (UNICAMP), Campinas, SP (Brazil)

    2016-12-26

    For more than half of the Southern African population, human development is limited by a lack of access to electricity and modern energy for cooking. Modern bioenergy merits consideration as one means to address this situation in areas where sufficient arable land is available. While numerous studies have concluded that Africa has significant biomass potential, they do not indicate by how much it can effectively reduce the use of traditional biomass and provide more accessible energy, especially at a country level. Here, we evaluate the potential of sugarcane to replace traditional biomass and fossil fuel and enlarge the access to electricity in Southern Africa. By using its current molasses for ethanol production, Swaziland could increase electricity generation by 40% using bagasse and replace 60% of cooking fuel or 30% of liquid fossil fuel. Sugarcane expansion over 1% of the pasture land in Angola, Mozambique, and Zambia could replace greater than 70% of cooking fuel. Bioelectricity generation from modest sugarcane expansion could be increased by 10% in Malawi, Mozambique, and Zambia and by 20% in Angola. Our results support the potential of sugarcane as a modern energy alternative for Southern Africa.

  7. Potential of Sugarcane in Modern Energy Development in Southern Africa

    International Nuclear Information System (INIS)

    Souza, Simone P.; Horta Nogueira, Luiz A.; Watson, Helen K.; Lynd, Lee Rybeck; Elmissiry, Mosad; Cortez, Luís A. B.

    2016-01-01

    For more than half of the Southern African population, human development is limited by a lack of access to electricity and modern energy for cooking. Modern bioenergy merits consideration as one means to address this situation in areas where sufficient arable land is available. While numerous studies have concluded that Africa has significant biomass potential, they do not indicate by how much it can effectively reduce the use of traditional biomass and provide more accessible energy, especially at a country level. Here, we evaluate the potential of sugarcane to replace traditional biomass and fossil fuel and enlarge the access to electricity in Southern Africa. By using its current molasses for ethanol production, Swaziland could increase electricity generation by 40% using bagasse and replace 60% of cooking fuel or 30% of liquid fossil fuel. Sugarcane expansion over 1% of the pasture land in Angola, Mozambique, and Zambia could replace greater than 70% of cooking fuel. Bioelectricity generation from modest sugarcane expansion could be increased by 10% in Malawi, Mozambique, and Zambia and by 20% in Angola. Our results support the potential of sugarcane as a modern energy alternative for Southern Africa.

  8. MAPPING OF TOURISM POTENTIAL: THE PRECONDITIONS FOR THE DEVELOPMENT OF TOURISM IN CONTINENTAL CROATIA

    Directory of Open Access Journals (Sweden)

    Mario Banožić

    2015-07-01

    Full Text Available Many Croatian scientists indicate that there are significant opportunities in tourism that can beneficially influence the overall socio-economic development of Croatia. It is recognised that Croatia has to follow more closely the contemporary tourism trends, in which much greater attention is given to ecology, the cultural identity of the destination, active vacations, service quality and selective forms of tourism development. There is also agreement that the clean sea, the coast, and the abundance of natural and cultural beauty are the advantages of Croatia’s tourism supply in the maritime part of the country. However, there are some discussions that the Continental part of Croatia is also abundant in natural beauty, cultural wealth, and gastronomy, and that it has many other underutilised tourism potentials. Different viewpoints on tourism in Croatia are based on statistical indicators, such as the level of development of tourist regions expressed through investments in infrastructure, the number of employed and the direct benefit of tourism to the economy. Despite the fact that the Continental part of Croatia abounds in tourism potential, what is offered is recognised only locally. This problem has negative impacts at the strategic level, as project planning and financing need to have a regional dimension. Some authors (Kušen, 1999; Koščak, 1998; Krippendorf, 1986; Müller, 1994; Stabler, 1996; Travis et al., 1994 have developed a cadastre of tourism potential, which has never been implemented. Therefore, this paper aims to map the tourism potentials of Continental Croatia by using the triple helix model, based on which regional tourism can be developed and future project funding ensured.

  9. Development of a calculation methodology for potential flow over irregular topographies

    International Nuclear Information System (INIS)

    Del Carmen, Alejandra F.; Ferreri, Juan C.; Boutet, Luis I.

    2003-01-01

    Full text: Computer codes for the calculation of potential flow fields over surfaces with irregular topographies have been developed. The flows past multiple simple obstacles and past the neighboring region of the Embalse Nuclear Power Station have been considered. The codes developed allow the calculation of velocities quite near the surface. It, in turn, imposed developing high accuracy techniques. The Boundary Element Method, using a linear approximation on triangular plane elements and an analytical integration methodology has been applied. A particular and quite efficient technique for the calculation of the solid angle at each node vertex was also considered. The results so obtained will be applied to predict the dispersion of passive pollutants coming from discontinuous emissions. (authors)

  10. Residents’ Attitudes towards Sustainable Tourism Development in a Historical-Cultural Village: Influence of Perceived Impacts, Sense of Place and Tourism Development Potential

    Directory of Open Access Journals (Sweden)

    He Zhu

    2017-01-01

    Full Text Available This study aims to assess the residents’ support for sustainable tourism development in a destination that is in the initial tourism development stage. Residents’ perception of sustainable tourism development potential, sense of place, perceived tourism impacts, and tourism development support were involved in this study. A total of 331 completed questionnaire surveys were collected in Luozhou, a historical-cultural village in China. The empirical data were analyzed using a structural equation modeling (SEM technique, and the results revealed that perceived collective benefits had a significant positive effect on tourism development support, whereas the other three perceived impacts’ influence were not significant. The relationship between residents’ sense of place and perceived collective and personal benefits, perceived personal costs and tourism development support, were significant. Additionally, residents’ perceptions of tourism development potential had a significant influence on perceived impact and tourism development support except for perceived personal benefits. Some practical implications of those findings for tourism planning and development are also discussed.

  11. Characterization of OAZ1 and its potential functions in goose follicular development

    Directory of Open Access Journals (Sweden)

    Bo Kang

    2017-03-01

    Conclusions: The goose OAZ1 structure confirms that OAZ1 plays an important role in ornithine decarboxylase-mediated regulation of polyamine homeostasis. Our findings provide an evidence for a potential function of OAZ1 in follicular development, ovulation and regression.

  12. Reevaluation of Turkey's hydropower potential and electric energy demand

    International Nuclear Information System (INIS)

    Yueksek, Omer

    2008-01-01

    This paper deals with Turkey's hydropower potential and its long-term electric energy demand predictions. In the paper, at first, Turkey's energy sources are briefly reviewed. Then, hydropower potential is analyzed and it has been concluded that Turkey's annual economically feasible hydropower potential is about 188 TWh, nearly 47% greater than the previous estimation figures of 128 TWh. A review on previous prediction models for Turkey's long-term electric energy demand is presented. In order to predict the future demand, new increment ratio scenarios, which depend on both observed data and future predictions of population, energy consumption per capita and total energy consumption, are developed. The results of 11 prediction models are compared and analyzed. It is concluded that Turkey's annual electric energy demand predictions in 2010, 2015 and 2020 vary between 222 and 242 (average 233) TWh; 302 and 356 (average 334) TWh; and 440 and 514 (average 476) TWh, respectively. A discussion on the role of hydropower in meeting long-term demand is also included in the paper and it has been predicted that hydropower can meet 25-35% of Turkey's electric energy demand in 2020

  13. Integrating future scenario‐based crop expansion and crop conditions to map switchgrass biofuel potential in eastern Nebraska, USA

    Science.gov (United States)

    Gu, Yingxin; Wylie, Bruce K.

    2018-01-01

    Switchgrass (Panicum virgatum) has been evaluated as one potential source for cellulosic biofuel feedstocks. Planting switchgrass in marginal croplands and waterway buffers can reduce soil erosion, improve water quality, and improve regional ecosystem services (i.e. it serves as a potential carbon sink). In previous studies, we mapped high risk marginal croplands and highly erodible cropland buffers that are potentially suitable for switchgrass development, which would improve ecosystem services and minimally impact food production. In this study, we advance our previous study results and integrate future crop expansion information to develop a switchgrass biofuel potential ensemble map for current and future croplands in eastern Nebraska. The switchgrass biomass productivity and carbon benefits (i.e. NEP: net ecosystem production) for the identified biofuel potential ensemble areas were quantified. The future scenario‐based (‘A1B’) land use and land cover map for 2050, the US Geological Survey crop type and Compound Topographic Index (CTI) maps, and long‐term (1981–2010) averaged annual precipitation data were used to identify future crop expansion regions that are suitable for switchgrass development. Results show that 2528 km2 of future crop expansion regions (~3.6% of the study area) are potentially suitable for switchgrass development. The total estimated biofuel potential ensemble area (including cropland buffers, marginal croplands, and future crop expansion regions) is 4232 km2 (~6% of the study area), potentially producing 3.52 million metric tons of switchgrass biomass per year. Converting biofuel ensemble regions to switchgrass leads to potential carbon sinks (the total NEP for biofuel potential areas is 0.45 million metric tons C) and is environmentally sustainable. Results from this study improve our understanding of environmental conditions and ecosystem services of current and future cropland systems in eastern Nebraska and provide

  14. Proteomics Analysis Reveals Previously Uncharacterized Virulence Factors in Vibrio proteolyticus

    Directory of Open Access Journals (Sweden)

    Ann Ray

    2016-07-01

    Full Text Available Members of the genus Vibrio include many pathogens of humans and marine animals that share genetic information via horizontal gene transfer. Hence, the Vibrio pan-genome carries the potential to establish new pathogenic strains by sharing virulence determinants, many of which have yet to be characterized. Here, we investigated the virulence properties of Vibrio proteolyticus, a Gram-negative marine bacterium previously identified as part of the Vibrio consortium isolated from diseased corals. We found that V. proteolyticus causes actin cytoskeleton rearrangements followed by cell lysis in HeLa cells in a contact-independent manner. In search of the responsible virulence factor involved, we determined the V. proteolyticus secretome. This proteomics approach revealed various putative virulence factors, including active type VI secretion systems and effectors with virulence toxin domains; however, these type VI secretion systems were not responsible for the observed cytotoxic effects. Further examination of the V. proteolyticus secretome led us to hypothesize and subsequently demonstrate that a secreted hemolysin, belonging to a previously uncharacterized clan of the leukocidin superfamily, was the toxin responsible for the V. proteolyticus-mediated cytotoxicity in both HeLa cells and macrophages. Clearly, there remains an armory of yet-to-be-discovered virulence factors in the Vibrio pan-genome that will undoubtedly provide a wealth of knowledge on how a pathogen can manipulate host cells.

  15. High-Grade Leiomyosarcoma Arising in a Previously Replanted Limb

    Directory of Open Access Journals (Sweden)

    Tiffany J. Pan

    2015-01-01

    Full Text Available Sarcoma development has been associated with genetics, irradiation, viral infections, and immunodeficiency. Reports of sarcomas arising in the setting of prior trauma, as in burn scars or fracture sites, are rare. We report a case of a leiomyosarcoma arising in an arm that had previously been replanted at the level of the elbow joint following traumatic amputation when the patient was eight years old. He presented twenty-four years later with a 10.8 cm mass in the replanted arm located on the volar forearm. The tumor was completely resected and pathology examination showed a high-grade, subfascial spindle cell sarcoma diagnosed as a grade 3 leiomyosarcoma with stage pT2bNxMx. The patient underwent treatment with brachytherapy, reconstruction with a free flap, and subsequently chemotherapy. To the best of our knowledge, this is the first case report of leiomyosarcoma developing in a replanted extremity. Development of leiomyosarcoma in this case could be related to revascularization, scar formation, or chronic injury after replantation. The patient remains healthy without signs of recurrence at three-year follow-up.

  16. Generalized magnetic Rosenbluth potentials

    International Nuclear Information System (INIS)

    Hassan, M.H.A.

    1977-12-01

    It is shown that the coefficients of friction and diffusion of the magnetized Balescu-Lenard equation describing the interaction of ion test particles with electron field particles can be derived from two scalar potentials, which reduce to the potentials derived previously when wave effects are neglected. The parts of the potentials describing ''wave effects'' are evaluated explicitly in the case of Maxwellian electrons and the results are compared with the unmagnetized Rosenbluth potentials. The correction is dominant when eta=Ωsub(e)/ωsub(e)(>)1

  17. The Potential of Women’s Organization for Rural Development in Sierra Leone

    Directory of Open Access Journals (Sweden)

    Theresa Tenneh Dick

    2013-01-01

    Full Text Available Organizations are among the preferred outlets women use both to voice societal prejudices against them and to showcase their potential for rural/community development. There is an increasing advocacy for gender equality, women’s empowerment and the integration of women folks into the socio-economic, political and cultural fabrics of society. Girl-child education and women-based capacity building programs such as micro-finance, entrepreneurship, political activism, etc. have surfaced prominently on these women’s empowerment efforts. In this study, a questionnaire-driven survey is conducted in two districts in southern Sierra Leone. The survey covers 36 influential women in 36 town-level communities in the country. The study analyzes the personal and organization characteristics of the women in relation to social perceptions and rural/community development. A large percent of the women surveyed are educated, married and belong to social organizations. In addition to other social/development organizations, women’s organizations are also present in each of the surveyed communities. Most of the women organizations are local in nature and operate entirely on funds raised from within the local communities. This display of organizational ability of the surveyed rural women shows a significant perceptional shift towards recognizing women folks as productive counterparts in our societies. This trend also psychologically strengthens the women community to take on tangible responsibilities that were ones meant for men only. The analysis also shows that rural women hold managerial and other administrative positions in the organizations which are strongly oriented towards various forms of rural/community development. This is a significant positive deviation from the traditional perception which has unduly confined the women folks to the backyard for centuries now. This trend not only has the potential of benefiting the millions more women languishing in

  18. Analytical W–He and H–He interatomic potentials for a W–H–He system

    International Nuclear Information System (INIS)

    Li Xiaochun; Shu Xiaolin; Liu Yinan; Yu Yi; Gao, F.; Lu Guanghong

    2012-01-01

    We have constructed W–He and H–He analytical bond-order potentials for a W–H–He system. In combination with the previously self-developed W–H potential [X.-C. Li, X. Shu, Y.-N. Liu, F. Gao, G.-H. Lu, J. Nucl. Mater. 408 (2011) 12] and the Hartree–Fock-dispersion pair potential (Aziz-potential) for He−He interactions, we demonstrate that such potentials behave well for reproducing various properties of the W–H–He system such as defect formation energies, structural properties, and diffusion barriers. Such potentials can be employed to model both the He behaviours and the H–He synergetic effects in the W–H–He system.

  19. Study of the renewable energy potential and development in Alsace

    International Nuclear Information System (INIS)

    2016-01-01

    This report is part of a study which aimed at assessing the possibility of a renewable energy production equal to or greater than Alsace energy production between 2020 and 2050. It comprised an analysis of potentials and deadlocks for the development of each renewable energy. After an overview of renewable energy production by the end of 2012, the report addresses the different sectors (solar, biomass fuel, geothermal, heat recovery, aero-thermal, wind, hydroelectricity, methanization, agricultural fuels, transports). For each of them, it proposes assessments for the different specific technical resources and processes. Then, after a synthesis of the obtained maximum theoretical resources, it reports the development of three scenarios (a trend-based one, a maximum one, and a proactive one) while addressing each resource within them

  20. Recruitment potential of a green alga Ulva flexuosa Wolfen dark preserved zoospore and its development

    Digital Repository Service at National Institute of Oceanography (India)

    Imchen, T.

    Green Alga Ulva flexuosa Wulfen Dark Preserved Zoospore and Its Development Temjensangba Imchen* National Institute of Oceanography (Council of Scientific and Industrial Research), Goa, India Abstract The recruitment potential and the ability of Ulva... factors play a role in the process of recruitment. Citation: Imchen T (2012) Recruitment Potential of a Green Alga Ulva flexuosa Wulfen Dark Preserved Zoospore and Its Development. PLoS ONE 7(3): e32651. doi:10.1371/journal.pone.0032651 Editor: Ross...

  1. Gestational Diabetes in Korea: Incidence and Risk Factors of Diabetes in Women with Previous Gestational Diabetes

    Directory of Open Access Journals (Sweden)

    Hak Chul Jang

    2011-02-01

    Full Text Available Korean women with a history of gestational diabetes mellitus (GDM have a 3.5 times greater risk of developing postpartum diabetes than the general population. The incidence of type 2 diabetes mellitus in early postpartum is reported as 10-15% in Korean women. A prospective follow-up study on Korean women with GDM showed that approximately 40% of women with previous GDM were expected to develop diabetes within 5 years postpartum. Independent risk factors for the development of diabetes in Korean women with previous GDM are pre-pregnancy body weight, gestational age at diagnosis, antepartum hyperglycemia on oral glucose tolerance test, low insulin response to oral glucose load, and family history of diabetes. Women with postpartum diabetes have greater body mass indexes, body weight, and waist circumferences than women with normal glucose tolerance. Multiple logistic regression analysis has revealed that waist circumference is the strongest obesity index along with systolic blood pressure and that triglyceride levels are a major independent risk factor for developing diabetes. These results in Korean women with previous GDM underline the importance of postpartum testing in Korean women diagnosed with GDM, and demonstrate that impaired B-cell function, obesity, and especially visceral obesity, are associated with the development of diabetes.

  2. Nuclear energy role and potential for global sustainable development

    International Nuclear Information System (INIS)

    Ujita, H.; Matsui, K.

    2006-01-01

    The long-term energy supply simulation that optimizes the energy system cost until 2100 for the world is being performed, by using the energy module of GRAPE model, where energy demand under the C02 emission constraint etc. is assumed. The model has been taken up for the trial calculation in I PCC the third report . Role and potential of nuclear energy system in the energy options is discussed here from the viewpoint of sustainable development with protecting from global warming. Taking the effort for energy conservation as major premise, carbon-sequestration for fossil fuel, renewable energy and nuclear energy should be altogether developed under the C02 constraint. Especially, fast breeder reactor will be attached importance to, as the 22nd century is approaching, due to its carbon free and resource limitless features when the nuclear generation cost is cheap as a current light water reactor level. It takes time around 30 years in order for breeding of Pu, a fast breeder reactor will begin to be introduced from around 2030. If the period for the technology establish of nuclear fuel cycle is assumed to be 30 years, it is necessary to start technical development right now. If the Kyoto Protocol, the emission constraint on only the developed countries, is extended in 21st century, it will promote the growth of nuclear power in the developed countries in the first half of the century. After 2050, the developing countries will face the shortage of uranium and plutonium. Carbon emission constraint should be covered all countries in the World not only for the developed countries but also for the developing countries. Therefore, it is important that the developing countries will use nuclear power effectively from the viewpoint of harmonization of energy growth and global environment. The policy that nuclear power is considered as Clean Development Mechanism would mitigate such global warming problems

  3. Effect of media composition, including gelling agents, on isolation of previously uncultured rumen bacteria.

    Science.gov (United States)

    Nyonyo, T; Shinkai, T; Tajima, A; Mitsumori, M

    2013-01-01

    The aim of this study was to develop novel anaerobic media using gellan gum for the isolation of previously uncultured rumen bacteria. Four anaerobic media, a basal liquid medium (BM) with agar (A-BM), a modified BM (MBM) with agar (A-MBM), an MBM with phytagel (P-MBM) and an MBM with gelrite (G-MBM) were used for the isolation of rumen bacteria and evaluated for the growth of previously uncultured rumen bacteria. Of the 214 isolates composed of 144 OTUs, 103 isolates (83 OTUs) were previously uncultured rumen bacteria. Most of the previously uncultured strains were obtained from A-MBM, G-MBM and P-MBM, but the predominant cultural members, isolated from each medium, differed. A-MBM and G-MBM showed significantly higher numbers of different OTUs derived from isolates than A-BM (P rumen bacteria were isolated from all media used, the ratio of previously uncultured bacteria to total isolates was increased in A-MBM, P-MBM and G-MBM. © 2012 The Society for Applied Microbiology.

  4. Effective exchange potentials for electronically inelastic scattering

    International Nuclear Information System (INIS)

    Schwenke, D.W.; Staszewska, G.; Truhlar, D.G.

    1983-01-01

    We propose new methods for solving the electron scattering close coupling equations employing equivalent local exchange potentials in place of the continuum-multiconfiguration-Hartree--Fock-type exchange kernels. The local exchange potentials are Hermitian. They have the correct symmetry for any symmetries of excited electronic states included in the close coupling expansion, and they have the same limit at very high energy as previously employed exchange potentials. Comparison of numerical calculations employing the new exchange potentials with the results obtained with the standard nonlocal exchange kernels shows that the new exchange potentials are more accurate than the local exchange approximations previously available for electronically inelastic scattering. We anticipate that the new approximations will be most useful for intermediate-energy electronically inelastic electron--molecule scattering

  5. Coal development potential in Pakistan

    Energy Technology Data Exchange (ETDEWEB)

    Khan, M N; Pelofsky, A H [eds.

    1986-01-01

    A total of 48 papers were presented, and covered the following topics: the current situation in Pakistan with respect to development and utilization of coal resources; the policies that have been responsible for the development and utilization of coal resources in Pakistan; coal development and utilization in other developing nations e.g. Indonesia, Greece, Philippines, China, Thailand and Haiti; and technological developments in coal exploration; extraction, handling, transport and utilization which could accelerate future development of Pakistan's coal resources. Specific subjects covered include the use of coal in the cement industry of Pakistan; the production of briquettes for domestic use, development and training of personnel for the coal industry; and sources of finance for coal development projects. Particular emphasis is given throughout the conference to the Lakhra coal mine/power plant project which aims to develop and effectively utilize the lignite reserves of Sind Province. 47 papers have been abstracted separately.

  6. Effects of soil organic matter on the development of the microbial polycyclic aromatic hydrocarbons (PAHs) degradation potentials

    International Nuclear Information System (INIS)

    Yang, Y.; Zhang, N.; Xue, M.; Lu, S.T.; Tao, S.

    2011-01-01

    The microbial activity in soils was a critical factor governing the degradation of organic micro-pollutants. The present study was conducted to analyze the effects of soil organic matter on the development of degradation potentials for polycyclic aromatic hydrocarbons (PAHs). Most of the degradation kinetics for PAHs by the indigenous microorganisms developed in soils can be fitted with the Logistic growth models. The microbial activities were relatively lower in the soils with the lowest and highest organic matter content, which were likely due to the nutrition limit and PAH sequestration. The microbial activities developed in humic acid (HA) were much higher than those developed in humin, which was demonstrated to be able to sequester organic pollutants stronger. The results suggested that the nutrition support and sequestration were the two major mechanisms, that soil organic matter influenced the development of microbial PAHs degradation potentials. - Research highlights: → PAH degradation kinetics obey Logistic model. → Degradation potentials depend on soil organic carbon content. → Humin inhibits the development of PAH degradation activity. → Nutrition support and sequestration regulate microbial degradation capacity. - Soil organic matter regulated PAH degradation potentials through nutrition support and sequestration.

  7. Potential involvement of the immune system in the development of endometriosis

    Directory of Open Access Journals (Sweden)

    Mwenda Jason M

    2003-12-01

    Full Text Available Abstract This article presents an overview of immunological factors and their role in the development of endometriosis, with emphasis on inflammatory cytokines, growth and adhesion factors. Although retrograde menstruation is a common phenomenon among women of reproductive age, not all women who have retrograde menstruation develop endometriosis. The development of endometriosis is hypothesised to be a complex process, which may be facilitated by several factors, including the quantity and quality of endometrial cells in peritoneal fluid (PF, increased inflammatory activity in PF, increased endometrial-peritoneal adhesion and angiogenesis, reduced immune surveillance and clearance of endometrial cells, and increased production of autoantibodies against endometrial cells. Potential biomarkers like cytokines and autoantibodies upregulated during development of endometriosis may be useful in the development of a non-surgical diagnostic tool. Although endometriosis can be treated using hormonal suppression, there is need for non-hormonal drugs, which can inhibit the development of endometriosis and alleviate pain or infertility without inhibition of ovulation. New molecules that modulate immune function in endometriosis should be the targets for future research.

  8. Impact of previously disadvantaged land-users on sustainable ...

    African Journals Online (AJOL)

    Impact of previously disadvantaged land-users on sustainable agricultural ... about previously disadvantaged land users involved in communal farming systems ... of input, capital, marketing, information and land use planning, with effect on ...

  9. Development of an empirical interatomic potential for the Ag–Ti system

    Energy Technology Data Exchange (ETDEWEB)

    Zhou, Ying, E-mail: y.zhou3@lboro.ac.uk [Department of Mathematical Sciences, Loughborough University, Leicestershire LE11 3TU (United Kingdom); Smith, Roger [Department of Mathematical Sciences, Loughborough University, Leicestershire LE11 3TU (United Kingdom); Kenny, Steven D. [Department of Materials, Loughborough University, Leicestershire LE11 3TU (United Kingdom); Lloyd, Adam L. [Department of Mathematical Sciences, Loughborough University, Leicestershire LE11 3TU (United Kingdom)

    2017-02-15

    Highlights: • A new modified embedded-atom method interatomic potential for Ag and Ti was developed. • Binding energies for various configurations were calculated using SIESTA and were used as the fitting target. • Two mixing rules for the embedded-atom method based on the same elemental potentials were also investigated. • The results showed that the MEAM with the optimised parameters gives the best agreement to the DFT results. - Abstract: Two interatomic potential mixing rules for the Ti–Ag system were investigated based on the embedded-atom method (EAM) elemental potentials. First principles calculations were performed using SIESTA for various configurations of the Ti–Ag system to see which model best fitted the ab initio results. The results showed that the surface energies, especially that of Ti, were not well fitted by either model and the surface binding energies differed from the ab initio calculations. As a result, the modified embedded-atom method (MEAM) was investigated. In contrast to the other models, surface energies for pure Ti calculated by MEAM were in good agreement with the experimental data and the ab initio results. The MEAM mixing rule was used to investigate Ag ad-atoms on Ti and Ti ad-atoms on Ag. The results showed good agreement with SIESTA after parameter optimisation.

  10. The Social Influences on the Realization of Genetic Potential for Intellectual Development.

    Science.gov (United States)

    Guo, Guang; Stearns, Elizabeth

    2002-01-01

    Hypothesizes that a child's realization of genetic potential for intellectual development depends on socioeconomic environment. Peabody Picture Vocabulary Test results were examined for a large sibling sample of African American and White adolescents from the National Longitudinal Study of Adolescent Health. When SES factors were considered…

  11. Influence of the Reform of Local Self-Government in Ukraine on the Formation and Development of Labor Potential

    Directory of Open Access Journals (Sweden)

    Kharuk Kateryna B.

    2015-09-01

    Full Text Available The article determines the peculiarities of formation and development of the labor potential in the process of the reforming local self-government in Ukraine. It has been found that an integration of population, the system of economic entities, infrastructure units, scientific-technical potential allows to determine the need for modern spatial forms of concentration of labor potential, i.e. for consolidated territorial communities. With the purpose of formation and development of labor potential, considering impacts of the reform of local self-government in Ukraine, the following activities has been proposed to be carried out: improving the living standards of rural residents, creation of productive jobs, socio-economic cooperation between communities, infrastructure development, use of natural resources, socio-labor, agricultural and industrial capacities, effective use of rural socio-labour potential, development of agricultural production, rural non-farm activities, development of social infrastructure, creation of advisory service and introduction of a system of continuous education, development of family medicine, collaboration with regional and central authorities, involvement of the regional budget funds, establishment of a fund for economic development, cooperation with domestic and foreign investors. It has been determined that the introduction of the above measures will affect the increase in employment within the consolidated territorial communities.

  12. The Potential of Religion in the Promotion and Implementation of the Concept of Sustainable Development

    Science.gov (United States)

    Sadowski, Ryszard F.

    2017-12-01

    This article presents religion's potential where the promotion and implementation of the concept of sustainable development are concerned. First inspired by Lynn White in the 1960s, discussion on religion's role in the ecological crisis now allows for an honest assessment of the ecological potential of various religious traditions and their contribution to the building of a sustainable world. This article on the one hand points to the religious inspirations behind the concept of sustainable development, and on the other highlights the joint action of representatives of religion and science in the name of sustainable development, as well as the involvement of religions in the concept's implementation.

  13. Developing a molecular platform for potential carbon dioxide fixing

    DEFF Research Database (Denmark)

    Mikkelsen, Mette; Jørgensen, Mikkel; Krebs, Frederik C

    2010-01-01

    This paper presents an attempt to develop a new system for fixing carbon dioxide from the atmosphere. The proposed molecular system has been designed to have the capacity to spontaneously bind CO2 from the atmosphere with high affinity. The molecular system is furthermore designed to have...... the ability to liberate CO2 at a later stage in the process, i.e., in a separate compartment. The liberated CO2 presents a carbon neutral way of obtaining pure CO2. The proposed molecular system is based on a small stable organic molecule that potentially have two forms: one without bound CO2 and one...

  14. Retrofitting the Low Impact Development Practices into Developed Urban areas Including Barriers and Potential Solution

    Science.gov (United States)

    Shafique, Muhammad; Kim, Reeho

    2017-06-01

    Low impact development (LID)/green infrastructure (GI) practices have been identified as the sustainable practices of managing the stormwater in urban areas. Due to the increasing population, most of the cities are more developing which results in the change of natural area into impervious areas (roads, buildings etc.). Moreover, urbanization and climate change are causing many water-related problems and making over cities unsafe and insecure. Under these circumstances, there is a need to introduce new stormwater management practices into developed cities to reduce the adverse impacts of urbanization. For this purpose, retrofitting low impact development practices demands more attention to reduce these water-related problems and trying to make our cities sustainable. In developed areas, there is a little space is available for the retrofitting of LID practices for the stormwater management. Therefore, the selection of an appropriate place to retrofitting LID practices needs more concern. This paper describes the successfully applied retrofitting LID practices around the globe. It also includes the process of applying retrofitting LID practices at the suitable place with the suitable combination. Optimal places for the retrofitting of different LID practices are also mentioned. This paper also highlights the barriers and potential solutions of retrofitting LID practices in urban areas.

  15. Retrofitting the Low Impact Development Practices into Developed Urban areas Including Barriers and Potential Solution

    Directory of Open Access Journals (Sweden)

    Shafique Muhammad

    2017-06-01

    Full Text Available Low impact development (LID/green infrastructure (GI practices have been identified as the sustainable practices of managing the stormwater in urban areas. Due to the increasing population, most of the cities are more developing which results in the change of natural area into impervious areas (roads, buildings etc.. Moreover, urbanization and climate change are causing many water-related problems and making over cities unsafe and insecure. Under these circumstances, there is a need to introduce new stormwater management practices into developed cities to reduce the adverse impacts of urbanization. For this purpose, retrofitting low impact development practices demands more attention to reduce these water-related problems and trying to make our cities sustainable. In developed areas, there is a little space is available for the retrofitting of LID practices for the stormwater management. Therefore, the selection of an appropriate place to retrofitting LID practices needs more concern. This paper describes the successfully applied retrofitting LID practices around the globe. It also includes the process of applying retrofitting LID practices at the suitable place with the suitable combination. Optimal places for the retrofitting of different LID practices are also mentioned. This paper also highlights the barriers and potential solutions of retrofitting LID practices in urban areas.

  16. A survey among potential employers for developing a curriculum in public health nutrition.

    Science.gov (United States)

    Torheim, Liv E; Granli, Gry I; Barikmo, Ingrid; Oshaug, Arne

    2009-08-01

    To describe which functions potential employers of public health nutritionists in Norway find important for a person trained in public health nutrition to be able to carry out. Further, to illustrate how the findings were used in the development of a curriculum for a bachelor in public health nutrition at Akershus University College. A non-random, cross-sectional survey using a questionnaire with both pre-coded and open-ended questions. Ninety-one establishments working in various fields more or less related to nutrition responded (response rate of 45 %). Local offices of the Norwegian Food Safety Authority were over-represented among respondents. Functions related to communication and food and nutrition laws and regulations were most frequently rated as important by the respondents. Functions in nutrition research, project work and policy and planning were also regarded important by more than half of the respondents. The priorities of the potential employers together with the additional comments and suggestions were taken into account when a new curriculum on public health nutrition was developed. The assessment of functions prioritized by employers of public health nutritionists gave a valuable input for developing a new curriculum in public health nutrition. It reflected the challenges of the real world that public health nutritionists will work in and therefore helped making the curriculum potentially more relevant.

  17. Fuel cell two-wheelers : good market potential in Shanghai and suggestions for development

    International Nuclear Information System (INIS)

    Li, L.; Yu, Z.; Gong, H.

    2005-01-01

    A feasibility study on the market potential of 2-wheel fuel cell vehicles in Shanghai, China was presented. The Chinese government has recently invested a considerable amount of money in fuel cell technology research programs. However, 2-wheel fuel cell vehicles are not included in the program's plans. Considering future transportation models and examining market demand, it was anticipated that the 2-wheel fuel cell vehicles have an enormous market potential in China. An outline of market demands was presented. Issues concerning technological availability, hydrogen supply availability and government policies were considered. An economic overview of Shanghai was presented. International trends in fuel cell vehicles were reviewed, as well as issues concerning traffic and environmental impacts. Recommended policies for development were presented. Supply and demand issues were also considered. At present, 2-wheelers are only at the conceptual and demonstration stage. A graduated commercial framework for fuel cell bicycles and scooters was presented, which included initial production and medium scale production phases as well as the development of a hydrogen supply network over a period of 9 years. It was concluded that, as there are more than 9 million bicycles and over 300,000 motorcycles in Shanghai, there is potentially a huge market and a good base the development phases and gradual commercialization of 2-wheel fuel cell vehicles. 9 refs., 4 tabs., 3 figs

  18. Evidence for nitrite-dependent anaerobic methane oxidation as a previously overlooked microbial methane sink in wetlands

    Science.gov (United States)

    Hu, Bao-lan; Shen, Li-dong; Lian, Xu; Zhu, Qun; Liu, Shuai; Huang, Qian; He, Zhan-fei; Geng, Sha; Cheng, Dong-qing; Lou, Li-ping; Xu, Xiang-yang; Zheng, Ping; He, Yun-feng

    2014-01-01

    The process of nitrite-dependent anaerobic methane oxidation (n-damo) was recently discovered and shown to be mediated by “Candidatus Methylomirabilis oxyfera” (M. oxyfera). Here, evidence for n-damo in three different freshwater wetlands located in southeastern China was obtained using stable isotope measurements, quantitative PCR assays, and 16S rRNA and particulate methane monooxygenase gene clone library analyses. Stable isotope experiments confirmed the occurrence of n-damo in the examined wetlands, and the potential n-damo rates ranged from 0.31 to 5.43 nmol CO2 per gram of dry soil per day at different depths of soil cores. A combined analysis of 16S rRNA and particulate methane monooxygenase genes demonstrated that M. oxyfera-like bacteria were mainly present in the deep soil with a maximum abundance of 3.2 × 107 gene copies per gram of dry soil. It is estimated that ∼0.51 g of CH4 m−2 per year could be linked to the n-damo process in the examined wetlands based on the measured potential n-damo rates. This study presents previously unidentified confirmation that the n-damo process is a previously overlooked microbial methane sink in wetlands, and n-damo has the potential to be a globally important methane sink due to increasing nitrogen pollution. PMID:24616523

  19. Potential for Development of Solar and Wind Resource in Bhutan

    Energy Technology Data Exchange (ETDEWEB)

    Gilman, P.; Cowlin, S.; Heimiller, D.

    2009-09-01

    With support from the U.S. Agency for International Development (USAID), the U.S. Department of Energy's National Renewable Energy Laboratory (NREL) produced maps and data of the wind and solar resources in Bhutan. The solar resource data show that Bhutan has an adequate resource for flat-plate collectors, with annual average values of global horizontal solar radiation ranging from 4.0 to 5.5 kWh/m2-day (4.0 to 5.5 peak sun hours per day). The information provided in this report may be of use to energy planners in Bhutan involved in developing energy policy or planning wind and solar projects, and to energy analysts around the world interested in gaining an understanding of Bhutan's wind and solar energy potential.

  20. Determining root correspondence between previously and newly detected objects

    Science.gov (United States)

    Paglieroni, David W.; Beer, N Reginald

    2014-06-17

    A system that applies attribute and topology based change detection to networks of objects that were detected on previous scans of a structure, roadway, or area of interest. The attributes capture properties or characteristics of the previously detected objects, such as location, time of detection, size, elongation, orientation, etc. The topology of the network of previously detected objects is maintained in a constellation database that stores attributes of previously detected objects and implicitly captures the geometrical structure of the network. A change detection system detects change by comparing the attributes and topology of new objects detected on the latest scan to the constellation database of previously detected objects.

  1. Development of global medium-energy nucleon-nucleus optical model potentials

    International Nuclear Information System (INIS)

    Madland, D.G.; Sierk, A.J.

    1997-01-01

    The authors report on the development of new global optical model potentials for nucleon-nucleus scattering at medium energies. Using both Schroedinger and Dirac scattering formalisms, the goal is to construct a physically realistic optical potential describing nucleon-nucleus elastic scattering observables for a projectile energy range of (perhaps) 20 meV to (perhaps) 2 GeV and a target mass range of 16 to 209, excluding regions of strong nuclear deformation. They use a phenomenological approach guided by conclusions from recent microscopic studies. The experimental database consists largely of proton-nucleus elastic differential cross sections, analyzing powers, spin-rotation functions, and total reaction cross sections, and neutron-nucleus total cross sections. They will use this database in a nonlinear least-squares adjustment of optical model parameters in both relativistic equivalent Schroedinger (including relativistic kinematics) and Dirac (second-order reduction) formalisms. Isospin will be introduced through the standard Lane model and a relativistic generalization of that model

  2. Effective intermolecular potential and critical point for C60 molecule

    Science.gov (United States)

    Ramos, J. Eloy

    2017-07-01

    The approximate nonconformal (ANC) theory is applied to the C60 molecule. A new binary potential function is developed for C60, which has three parameters only and is obtained by averaging the site-site carbon interactions on the surface of two C60 molecules. It is shown that the C60 molecule follows, to a good approximation, the corresponding states principle with n-C8H18, n-C4F10 and n-C5F12. The critical point of C60 is estimated in two ways: first by applying the corresponding states principle under the framework of the ANC theory, and then by using previous computer simulations. The critical parameters obtained by applying the corresponding states principle, although very different from those reported in the literature, are consistent with the previous results of the ANC theory. It is shown that the Girifalco potential does not correspond to an average of the site-site carbon-carbon interaction.

  3. Sustainable Production of Second-Generation Biofuels. Potential and perspectives in major economies and developing countries

    Energy Technology Data Exchange (ETDEWEB)

    Eisentraut, A

    2010-02-15

    The paper focuses on opportunities and risks presented by second-generation biofuels technologies in eight case study countries: Brazil, Cameroon, China, India, Mexico, South Africa, Tanzania and Thailand. The report begins by exploring the state of the art of second-generation technologies and their production, followed by projections of future demand and a discussion of drivers of that demand. The report then delves into various feedstock options and the global potential for bioenergy production. The final chapter offers a look at the potential for sustainable second-generation biofuel production in developing countries including considerations of economic, social and environmental impacts. Key findings of the report include that: second-generation biofuels produced from agricultural and forestry residues can play a crucial role in the transport sector without competing with food production; the potential for second-generation biofuels should be mobilized in emerging and developing countries where a large share of global residues is produced; less-developed countries will first need to invest in agricultural production and infrastructure in order to improve the framework conditions for the production of second-generation biofuels; financial barriers to production exist in many developing countries; and the suitability of second-generation biofuels against individual developing countries' needs should be evaluated.

  4. Sustainable Production of Second-Generation Biofuels. Potential and perspectives in major economies and developing countries

    International Nuclear Information System (INIS)

    Eisentraut, A.

    2010-02-01

    The paper focuses on opportunities and risks presented by second-generation biofuels technologies in eight case study countries: Brazil, Cameroon, China, India, Mexico, South Africa, Tanzania and Thailand. The report begins by exploring the state of the art of second-generation technologies and their production, followed by projections of future demand and a discussion of drivers of that demand. The report then delves into various feedstock options and the global potential for bioenergy production. The final chapter offers a look at the potential for sustainable second-generation biofuel production in developing countries including considerations of economic, social and environmental impacts. Key findings of the report include that: second-generation biofuels produced from agricultural and forestry residues can play a crucial role in the transport sector without competing with food production; the potential for second-generation biofuels should be mobilized in emerging and developing countries where a large share of global residues is produced; less-developed countries will first need to invest in agricultural production and infrastructure in order to improve the framework conditions for the production of second-generation biofuels; financial barriers to production exist in many developing countries; and the suitability of second-generation biofuels against individual developing countries' needs should be evaluated.

  5. Sustainable Production of Second-Generation Biofuels. Potential and perspectives in major economies and developing countries

    Energy Technology Data Exchange (ETDEWEB)

    Eisentraut, A.

    2010-02-15

    The paper focuses on opportunities and risks presented by second-generation biofuels technologies in eight case study countries: Brazil, Cameroon, China, India, Mexico, South Africa, Tanzania and Thailand. The report begins by exploring the state of the art of second-generation technologies and their production, followed by projections of future demand and a discussion of drivers of that demand. The report then delves into various feedstock options and the global potential for bioenergy production. The final chapter offers a look at the potential for sustainable second-generation biofuel production in developing countries including considerations of economic, social and environmental impacts. Key findings of the report include that: second-generation biofuels produced from agricultural and forestry residues can play a crucial role in the transport sector without competing with food production; the potential for second-generation biofuels should be mobilized in emerging and developing countries where a large share of global residues is produced; less-developed countries will first need to invest in agricultural production and infrastructure in order to improve the framework conditions for the production of second-generation biofuels; financial barriers to production exist in many developing countries; and the suitability of second-generation biofuels against individual developing countries' needs should be evaluated.

  6. Crossing the Barriers: An Analysis of Land Access Barriers to Geothermal Development and Potential Improvement Scenarios

    Energy Technology Data Exchange (ETDEWEB)

    Levine, Aaron L [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Young, Katherine R [National Renewable Energy Laboratory (NREL), Golden, CO (United States)

    2017-10-04

    Developers have identified many non-technical barriers to geothermal power development, including access to land. Activities required for accessing land, such as environmental review and private and public leasing can take a considerable amount of time and can delay or prevent project development. This paper discusses the impacts to available geothermal resources and deployment caused by land access challenges, including tribal and cultural resources, environmentally sensitive areas, biological resources, land ownership, federal and state lease queues, and proximity to military installations. In this analysis, we identified challenges that have the potential to prevent development of identified and undiscovered hydrothermal geothermal resources. We found that an estimated 400 MW of identified geothermal resource potential and 4,000 MW of undiscovered geothermal resource potential were either unallowed for development or contained one or more significant barriers that could prevent development at the site. Potential improvement scenarios that could be employed to overcome these barriers include (1) providing continuous funding to the U.S. Forest Service (USFS) for processing geothermal leases and permit applications and (2) the creation of advanced environmental mitigation measures. The model results forecast that continuous funding to the USFS could result in deployment of an additional 80 MW of geothermal capacity by 2030 and 124 MW of geothermal capacity by 2050 when compared to the business-as-usual scenario. The creation of advanced environmental mitigation measures coupled with continuous funding to the USFS could result in deployment of an additional 97 MW of geothermal capacity by 2030 and 152 MW of geothermal capacity by 2050 when compared to the business-as-usual scenario. The small impact on potential deployment in these improvement scenarios suggests that these 4,400 MW have other barriers to development in addition to land access. In other words, simply

  7. Technique for sparing previously irradiated critical normal structures in salvage proton craniospinal irradiation

    International Nuclear Information System (INIS)

    McDonald, Mark W; Wolanski, Mark R; Simmons, Joseph W; Buchsbaum, Jeffrey C

    2013-01-01

    Cranial reirradiation is clinically appropriate in some cases but cumulative radiation dose to critical normal structures remains a practical concern. The authors developed a simple technique in 3D conformal proton craniospinal irradiation (CSI) to block organs at risk (OAR) while minimizing underdosing of adjacent target brain tissue. Two clinical cases illustrate the use of proton therapy to provide salvage CSI when a previously irradiated OAR required sparing from additional radiation dose. The prior radiation plan was coregistered to the treatment planning CT to create a planning organ at risk volume (PRV) around the OAR. Right and left lateral cranial whole brain proton apertures were created with a small block over the PRV. Then right and left lateral “inverse apertures” were generated, creating an aperture opening in the shape of the area previously blocked and blocking the area previously open. The inverse aperture opening was made one millimeter smaller than the original block to minimize the risk of dose overlap. The inverse apertures were used to irradiate the target volume lateral to the PRV, selecting a proton beam range to abut the 50% isodose line against either lateral edge of the PRV. Together, the 4 cranial proton fields created a region of complete dose avoidance around the OAR. Comparative photon treatment plans were generated with opposed lateral X-ray fields with custom blocks and coplanar intensity modulated radiation therapy optimized to avoid the PRV. Cumulative dose volume histograms were evaluated. Treatment plans were developed and successfully implemented to provide sparing of previously irradiated critical normal structures while treating target brain lateral to these structures. The absence of dose overlapping during irradiation through the inverse apertures was confirmed by film. Compared to the lateral X-ray and IMRT treatment plans, the proton CSI technique improved coverage of target brain tissue while providing the least

  8. Identification of informative features for predicting proinflammatory potentials of engine exhausts.

    Science.gov (United States)

    Wang, Chia-Chi; Lin, Ying-Chi; Lin, Yuan-Chung; Jhang, Syu-Ruei; Tung, Chun-Wei

    2017-08-18

    The immunotoxicity of engine exhausts is of high concern to human health due to the increasing prevalence of immune-related diseases. However, the evaluation of immunotoxicity of engine exhausts is currently based on expensive and time-consuming experiments. It is desirable to develop efficient methods for immunotoxicity assessment. To accelerate the development of safe alternative fuels, this study proposed a computational method for identifying informative features for predicting proinflammatory potentials of engine exhausts. A principal component regression (PCR) algorithm was applied to develop prediction models. The informative features were identified by a sequential backward feature elimination (SBFE) algorithm. A total of 19 informative chemical and biological features were successfully identified by SBFE algorithm. The informative features were utilized to develop a computational method named FS-CBM for predicting proinflammatory potentials of engine exhausts. FS-CBM model achieved a high performance with correlation coefficient values of 0.997 and 0.943 obtained from training and independent test sets, respectively. The FS-CBM model was developed for predicting proinflammatory potentials of engine exhausts with a large improvement on prediction performance compared with our previous CBM model. The proposed method could be further applied to construct models for bioactivities of mixtures.

  9. Teacher's Ability to Develop Learning Materials Potentially Mathematical Discourse

    Directory of Open Access Journals (Sweden)

    Hamdani Hamdani

    2017-10-01

    Full Text Available In the process of learning in the field, the teacher still dominates the conversation while the students as a passive listener. As a result, not only the communication skills of students who are less developed, the understanding of student material is also lacking. Therefore it is necessary to research the ability of teachers in developing learning tools potentially mathematical discourse to improve students' mathematical communication skills. The research method used is descriptive. Research activities include: identification of problems through questionnaires, observation, and interviews; teacher training; teachers develop learning tools; validation; and enhancement of the device by the teacher. The subject of this research is the junior high school mathematics teacher from several districts in the border area of Sambas-Sarawak Regency. The results show that in every learning mathematics there is always a conversation between teachers and students, but rarely use the question "why" and "how". Most teacher-made lesson plans contain scenarios of conversations between teachers and students, but just plain questioning, have not led to a debate between each other so that understanding becomes deeper. Student worksheet made by the teacher in the form of a matter of the ordinary story, rarely load non-routine problem let alone open-ended.

  10. Granulomatous lobular mastitis: report of a case with previously undescribed histopathological abnormalities.

    Science.gov (United States)

    Axelsen, R A; Reasbeck, P

    1988-10-01

    A 41-yr-old multiparous woman presented with a discrete breast lump which proved histologically to be an example of granulomatous lobular mastitis. The clinical and histological features were similar to those noted in previous reports. Additional histological features in the present case were an intense mononuclear cell infiltration of lobular and ductal epithelium, associated with nuclear fragments morphologically suggestive of apoptosis. These appearances, which have not previously been described, are illustrated, together with the more classical features of the condition well demonstrated by the present case. The novel histological features noted here suggest that the development of granulomatous lobular mastitis may be at least in part immunologically mediated, and that the cellular infiltrates seen may be a manifestation of cell-mediated destruction of mammary epithelium.

  11. The Potential Development of Betawi Culinary as an Ecotourism Product in Jakarta

    Directory of Open Access Journals (Sweden)

    Dhian Tyas Untari

    2016-11-01

    Full Text Available The aims of this research were to rebuild the existence of Betawi culinary. The objectives of this research were representing the values of socio-cultural of Betawi culinary, determining the aspects of supply and demand, and developing strategies to improve Betawi culinary potential as an ecotourism products. The research consists method consists of three stages. Those were representation test, market test, and arranging alternatives strategic. The results show that to improve Betawi culinary as the ecotourism products in Jakarta; it can be done with a series of strategies, classified into three classifications. Those are market penetration, market development, and product development. The result is expected to be a reference to the development of Betawi culinary ecotourismas one of the products in Jakarta.

  12. Reconciling semiclassical and Bohmian mechanics. III. Scattering states for continuous potentials

    International Nuclear Information System (INIS)

    Trahan, Corey; Poirier, Bill

    2006-01-01

    In a previous paper [B. Poirier, J. Chem. Phys. 121, 4501 (2004)] a unique bipolar decomposition Ψ=Ψ 1 +Ψ 2 was presented for stationary bound states Ψ of the one-dimensional Schroedinger equation, such that the components Ψ 1 and Ψ 2 approach their semiclassical WKB analogs in the large-action limit. The corresponding bipolar quantum trajectories, as defined in the usual Bohmian mechanical formulation, are classical-like and well behaved, even when Ψ has many nodes or is wildly oscillatory. A modification for discontinuous potential stationary scattering states was presented in a second, companion paper [C. Trahan and B. Poirier, J. Chem. Phys.124, 034115 (2006), previous paper], whose generalization for continuous potentials is given here. The result is an exact quantum scattering methodology using classical trajectories. For additional convenience in handling the tunneling case, a constant-velocity-trajectory version is also developed

  13. 77 FR 5998 - Airworthiness Directives; EADS CASA (Type Certificate Previously Held by Construcciones...

    Science.gov (United States)

    2012-02-07

    ... Airworthiness Directives; EADS CASA (Type Certificate Previously Held by Construcciones Aeronauticas, S.A... proposed to correct an unsafe condition for the specified products. The MCAI states: EADS-CASA received... address this condition, EADS-CASA has developed an engine condition control cable P/N 35-56382-0005 with...

  14. Justification of the Trade Enterprises Development Strategy in the Process of Strategic Management of the Marketing Potential

    Directory of Open Access Journals (Sweden)

    Grosul Viktoriya A.

    2013-11-01

    Full Text Available The article justifies a necessity of strategic management of marketing potential of retail trade enterprises. The article develops a general structural and logic scheme of the process of strategic management of the marketing potential of a trade enterprise taking into account specific features of the trade industry. It establishes that the main key issue in the theory of strategic management is argumentation of selection of the basic strategy of development of a subject of economy. It justifies a scientific and methodical approach to selection of the basic strategy of development of a trade enterprise in the process of management of the marketing potential, main stages of which are: assessment of the level of loyalty of external marketing environment; identification of marketing stratagems; and selection of the enterprise development strategy. The article offers to use the model of marketing stratagem, the components of which are policy of management of the marketing potential, strategic market position of the enterprise and level of loyalty of external marketing environment. The article develops an interactive strategic cube of formation of the complex of marketing stratagems on the basis of use of which marketing stratagems for various trade networks of the Kharkiv region are identified and strategies of their further development are justified.

  15. Development of an EAM potential for simulation of radiation damage in Fe-Cr alloys

    International Nuclear Information System (INIS)

    Wallenius, J.; Abrikosov, I.A.; Chakarova, R.; Lagerstedt, C.; Malerba, L.; Olsson, P.; Pontikis, V.; Sandberg, N.; Terentyev, D.

    2004-01-01

    We have developed a set of EAM potentials for simulation of Fe-Cr alloys. By relaxing the requirement of reproducing the pressure-volume relation at short distances and by fitting to the thermal expansion coefficients of Fe and Cr, stability of the self-interstitial could be obtained. For Cr, properties of the paramagnetic state were applied, providing a positive Cauchy pressure. Mixed Fe-Cr pair potentials were fitted to the calculated mixing enthalpy of ferromagnetic Fe-Cr. Simulation of thermal ageing in Fe-Cr alloys using the Fe-20Cr potential exhibited pronounced Cr-precipitation for temperatures below 900 K, a feature not observed at any temperature using a potential fitted to the mixing enthalpy of Fe-5Cr

  16. WP-Cave - assessment of feasibility, safety and development potential

    International Nuclear Information System (INIS)

    1989-09-01

    According to SKB R and D-programme 1986, alternative disposal methods will be investigated to provide a basis for selecting a site and a repository system for the Swedish spent nuclear fuel. The present report is a comparison between the WP-Cave and the reference concept KBS-3. The comparison has resulted in the following conclusions: - Both concepts are judged to be able to provide adequate safety. - A utilization of the potential of the WP-Cave requires, however, extensive development in areas where the current state of knowledge and available data are incomplete. - The higher temperatures in the WP-Cave lead to greater uncertainty as to long-term performance. Reducing this uncertainty would require many yaers of research and substantial resources. - Both repositories, including the barriers they incorporate, could be built with a normal adaption of available technology. -It is not possible to say today whether it would be simpler to find suitable sites for one design or the other. - The WP-Cave is considerably more expensive. A future research direction based on a concentrated emplacement of spent fuel along the lines of the WP-Cave is therefore judged to entail greater uncertainty as regards the possibilities of achieving acceptable safety and to require greater resources for research and development, at the same time as the costs of building the repository would be higher. The studies of the WP-Cave as an integral system should therfore be discontinued. Certain barrier designs in the WP-Cave could also be utulized in repository designs with lower temperature, for example the reduction potential of the steel canisters and the hydraulic cage's diversion of groundwater. Studies within these areas are being conducted within SKB and should continue

  17. Cancer-Specific and All-Cause Mortality in Kidney Transplant Recipients With and Without Previous Cancer.

    Science.gov (United States)

    Viecelli, Andrea K; Lim, Wai H; Macaskill, Petra; Chapman, Jeremy R; Craig, Jonathan C; Clayton, Philip; Cohney, Solomon; Carroll, Robert; Wong, Germaine

    2015-12-01

    For dialysis patients with a cancer history, a period of surveillance is generally recommended before listing for transplantation. However, the outcomes of patients with cancer recurrence and/or a second primary cancer after transplantation are unknown. To determine the prognosis of kidney transplant recipients who developed cancer after transplantation and whether this varied with cancer types (first cancer, recurrence, second primary cancer). Using data from the Australian and New Zealand Dialysis and Transplant Registry, we compared the cancer-specific and all-cause mortality among recipients with different cancer types using adjusted Cox proportional hazard models. Of the 21,415 recipients transplanted between 1965 and 2012, 3% (651 of 21,415) had a previous cancer history. A total of 2840 (13%) recipients developed cancer after the first transplant, of whom 2760 (97.2%) developed a first cancer, 23 (0.8%) experienced cancer recurrence, and 57 (2%) developed a second primary cancer. There were no significant differences in the risks of cancer-specific and all-cause mortality between recipients who developed their first cancer after transplant, those with cancer recurrence (adjusted hazard ratios [aHRs], 0.79; 95% confidence interval [95% CI], 0.38-1.67; P = 0.54 and aHRs, 0.86; 95% CI, 0.45-1.66; P = 0.66, respectively) and recipients who developed a second primary cancer after transplantation (aHRs, 1.01; 95%CI, 0.63-1.62; P = 0.95 and aHRs, 1.16; 95% CI, 0.79-1.69; P = 0.45, respectively). Among patients with a previous history of malignancy, recurrent and second primary cancers are infrequent after renal transplantation. A history of previous malignancy does not have an additive effect on the cancer-specific and overall survival of kidney transplant recipients who develop cancer.

  18. The Antibacterial Potential of Fermented Taro and Its Development as a Food Preservative

    National Research Council Canada - National Science Library

    Muller, Wayne

    2002-01-01

    ...: The antibacterial potential of the fermented taro and its development as a food preservative. In an attempt to understand the natural fermentation of taro to poi, bacteria have been isolated from freeze dried poi produced in Hawaii...

  19. [Assessment, delivery and peripartum care in the case of a uterine rupture during labor of a woman with a previous C-section].

    Science.gov (United States)

    Parrilla-Fernández, Alberto; Manrique-Tejedor, Javier; Figuerol-Calderó, M Inmaculada; García-Romero, Verónica

    Uterine rupture is a rare but severe complication in obstetrics. A previous C-section is the most important risk factor. Its incidence during labor in women with a previous C-section is of approximately 0.3-0.47%, being potentially severe. We present the case of a pregnant women with a previous C-section who suffered uterine rupture during labor. The rapid assessment and action of the midwife and obstetric team was essential to obtain a successful obstetric outcome, avoiding maternal and fetal mortality; and nursing care given to the mother and the newborn after birth contributed to achieving a normal postpartum. It is necessary to have specific knowledge about this condition that, despite rare, can present insidiously with a potential risk for the mother and the fetus. Copyright © 2016 Elsevier España, S.L.U. All rights reserved.

  20. Revision and simplification of the boarding previous minimum of the lumbar column

    International Nuclear Information System (INIS)

    Lazannec, JY; Del Vecchio, R; Ramare, S; Saillant, G

    2001-01-01

    This paper describes the boarding retroperineal previous minimum, which provides access at any level discal and vertebral between T12 and S1. It is carried out a technique of dissection retroperineal that facilitates the renal and duodenum-pancreatic mobilization to consent to the face previous left of the whole lumbar column and of the thoracic-lumbar union. They were carried out careful anatomical dissections in fresh cadavers and preserved to determine the topography and the anatomical relationships of interest and this way to develop a sure boarding and easily reproducible. Special attention has been paid to the description of the lumbar veins and the anastomosis between the vein renal left and the hemiacigos system for the exhibition of the expensive left anterolateral of T12 and L1. A series of 94 patients is reported with lesions caused by traumas or degenerative processes. For all the lumbar levels, even in-patient with antecedents of surgery intraperitoneal, the boarding minimum retroperitoneal, was safe for the kidneys, ureters, spleen, hypo gastric plexus and duodenum-pancreatic union. Better cosmetic results are reported, decrease of the time surgical, scarce bled intraoperatory and easiness for the decortications and placement of implants. The previous boarding minimum retro peritoneal of the column developed starting from the boarding classic retroperineals, offers significant advantages on the endoscopic techniques, which require sophisticated machinery and they are technically plaintiffs. The exhibition of all the lumbar levels, as well as the reduction maneuvers and placement of implants, they can be carried out with easiness without causing muscular damage

  1. The biomechanics of running in athletes with previous hamstring injury: A case-control study.

    Science.gov (United States)

    Daly, C; Persson, U McCarthy; Twycross-Lewis, R; Woledge, R C; Morrissey, D

    2016-04-01

    Hamstring injury is prevalent with persistently high reinjury rates. We aim to inform hamstring rehabilitation by exploring the electromyographic and kinematic characteristics of running in athletes with previous hamstring injury. Nine elite male Gaelic games athletes who had returned to sport after hamstring injury and eight closely matched controls sprinted while lower limb kinematics and muscle activity of the previously injured biceps femoris, bilateral gluteus maximus, lumbar erector spinae, rectus femoris, and external oblique were recorded. Intergroup comparisons of muscle activation ratios and kinematics were performed. Previously injured athletes demonstrated significantly reduced biceps femoris muscle activation ratios with respect to ipsilateral gluteus maximus (maximum difference -12.5%, P = 0.03), ipsilateral erector spinae (maximum difference -12.5%, P = 0.01), ipsilateral external oblique (maximum difference -23%, P = 0.01), and contralateral rectus femoris (maximum difference -22%, P = 0.02) in the late swing phase. We also detected sagittal asymmetry in hip flexion (maximum 8°, P = 0.01), pelvic tilt (maximum 4°, P = 0.02), and medial rotation of the knee (maximum 6°, P = 0.03) effectively putting the hamstrings in a lengthened position just before heel strike. Previous hamstring injury is associated with altered biceps femoris associated muscle activity and potentially injurious kinematics. These deficits should be considered and addressed during rehabilitation. © 2015 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  2. How to actualize potential: a bioecological approach to talent development.

    Science.gov (United States)

    Ceci, Stephen J; Williams-Ceci, Sterling; Williams, Wendy M

    2016-08-01

    Bioecological theory posits three interacting principles to explain developmental outcomes such as fluctuating achievement levels and changing heritability coefficients. Here, we apply the theory to the domain of talent development, by reviewing short-term and long-term cognitive interventions. We argue that macro-level analyses of cultural practices (e.g., matrilineal inheritance and property ownership) and national systems of education are consistent with the bioecological theory; when the findings from these analyses are unpacked, the engines that drive them are so-called proximal processes. This finding has implications for the design and delivery of instruction and the development of talent. We argue that talent is fostered by the same three bioecological mechanisms that explain the actualization of genetic potential. We conclude by discussing several self-descriptions and personal narratives by gifted students in which they spontaneously refer to these bioecological mechanisms in their own talent-development processes. Similar testimonials have been documented by historic talent researchers such as Benjamin Bloom, noting the importance of continual adjustments in feedback. © 2016 New York Academy of Sciences.

  3. The potentials of rural tourism in developing rural areas in Albania

    Directory of Open Access Journals (Sweden)

    Henrietta Nagy

    2017-12-01

    Full Text Available The inspiration that drove us to this study is that conventional tourism in Albania is focused more on promoting seaside, cultural tourism, luxury resorts, etc. which has demonstrated a good trend. At the same time, specific parts of the country have been abandoned due to their underdeveloped situation. Given their assets as constructed and indigenous habitat, they progressively appear as regions for rural tourism development. It could provide good development opportunities in remote mountainous areas that every day more are abandoned by the population because they do not have enough employment opportunities. But as for other rural areas which have a great potential for development of rural tourism, they are not preferred by the population either to live because they do not have developed agriculture. They do not provide the opportunity to earn enough money to live on at the appropriate standard. So the development of rural tourism would help the population in such areas to diversify their activities and earn some extra income, motivating inhabitants to stay in their own areas. Overall, it would contribute to the balanced development of the regions of Albania.

  4. Localized palmar-plantar epidermal hyperplasia: a previously undefined dermatologic toxicity to sorafenib.

    Science.gov (United States)

    Beldner, Matthew; Jacobson, Michael; Burges, Gene E; Dewaay, Deborah; Maize, John C; Chaudhary, Uzair B

    2007-10-01

    The development of multitargeted tyrosine kinase inhibitors has provided significant advances in the treatment of renal cell carcinoma. This case describes initial therapy for managing renal cell cancer with the administration of sorafenib, a multitargeted tyrosine kinase inhibitor. We report the development of localized palmar-plantar epidermal hyperplasia, a rare but significant cutaneous adverse event from sorafenib therapy. Mild-to-moderate dermatologic toxicity from sorafenib has been well described in the literature. We also review the current knowledge and the proposed hypothesis for the development of cutaneous events related to tyrosine kinase inhibitors. This particular case represents a unique form of dermatologic toxicity to sorafenib that has not previously been described in the literature.

  5. Fully depleted CMOS pixel sensor development and potential applications

    Energy Technology Data Exchange (ETDEWEB)

    Baudot, J.; Kachel, M. [Universite de Strasbourg, IPHC, 23 rue du Loess 67037 Strasbourg (France); CNRS, UMR7178, 67037 Strasbourg (France)

    2015-07-01

    CMOS pixel sensors are often opposed to hybrid pixel sensors due to their very different sensitive layer. In standard CMOS imaging processes, a thin (about 20 μm) low resistivity epitaxial layer acts as the sensitive volume and charge collection is mostly driven by thermal agitation. In contrast, the so-called hybrid pixel technology exploits a thick (typically 300 μm) silicon sensor with high resistivity allowing for the depletion of this volume, hence charges drift toward collecting electrodes. But this difference is fading away with the recent availability of some CMOS imaging processes based on a relatively thick (about 50 μm) high resistivity epitaxial layer which allows for full depletion. This evolution extents the range of applications for CMOS pixel sensors where their known assets, high sensitivity and granularity combined with embedded signal treatment, could potentially foster breakthrough in detection performances for specific scientific instruments. One such domain is the Xray detection for soft energies, typically below 10 keV, where the thin sensitive layer was previously severely impeding CMOS sensor usage. Another application becoming realistic for CMOS sensors, is the detection in environment with a high fluence of non-ionizing radiation, such as hadron colliders. However, when considering highly demanding applications, it is still to be proven that micro-circuits required to uniformly deplete the sensor at the pixel level, do not mitigate the sensitivity and efficiency required. Prototype sensors in two different technologies with resistivity higher than 1 kΩ, sensitive layer between 40 and 50 μm and featuring pixel pitch in the range 25 to 50 μm, have been designed and fabricated. Various biasing architectures were adopted to reach full depletion with only a few volts. Laboratory investigations with three types of sources (X-rays, β-rays and infrared light) demonstrated the validity of the approach with respect to depletion, keeping a

  6. Production Systems and Potential Development of Corn in West Pasaman Districts

    Directory of Open Access Journals (Sweden)

    Yulmar Jastra

    2015-09-01

    Full Text Available Maize (Zea mays L. is the second national food crop after rice and its role is increasing in line increase of population, livestock operations, and development of raw material corn processing industry. This research is a descriptive qualitative and quantitative as well as done in stages, namely: pre -study in order neighbor information gathering and general condition of farmers in the districts of West Pasaman, intensive desk study on the extent of data and the development of hybrid corn and all information obtained from pre -study activities; observation, field survey. This study aims to: identify systems of maize production in West Pasaman, identify potential areas of development and analysis of maize farming, Prepare Corn Development Action Programme in West Pasaman. Age maize farmers in West Pasaman between 40-60 years old, with old school for 9 years and the number of family members of farmers 5. The highest maize production in West Pasaman district occurred in 2009 amounted to 364 287 tonnes with 44 793 ha of harvested area and productivity of 6.99 tonnes/ha, in 2010, a decline in production to 220 761 tonnes with a productivity of 6.3 tons /ha due to a decline in harvested area into 33 757 ha. And in 2011 the production of corn production back to normal by 286 078 tons / year with 44 360 ha of harvested area and productivity of 6.50 tonnes/ha. Potential land that can be used to achieve the 142 850 ha of maize farming dominated peat and mineral soil of each area of 7,550 ha and 16,550 ha. Of corn farming can provide a gain of Rp 8,860,000,-/ha . When the period of 4 months of the corn crop corn farmer income per month is Rp 2.215.000,-

  7. Development of a prediction model for the cost saving potentials in implementing the building energy efficiency rating certification

    International Nuclear Information System (INIS)

    Jeong, Jaewook; Hong, Taehoon; Ji, Changyoon; Kim, Jimin; Lee, Minhyun; Jeong, Kwangbok; Koo, Choongwan

    2017-01-01

    Highlights: • This study evaluates the building energy efficiency rating (BEER) certification. • Prediction model was developed for cost saving potentials by the BEER certification. • Prediction model was developed using LCC analysis, ROV, and Monte Carlo simulation. • Cost saving potential was predicted to be 2.78–3.77% of the construction cost. • Cost saving potential can be used for estimating the investment value of BEER. - Abstract: Building energy efficiency rating (BEER) certification is an energy performance certificates (EPCs) in South Korea. It is critical to examine the cost saving potentials of the BEER-certification in advance. This study aimed to develop a prediction model for the cost saving potentials in implementing the BEER-certification, in which the cost saving potentials included the energy cost savings of the BEER-certification and the relevant CO_2 emissions reduction as well as the additional construction cost for the BEER-certification. The prediction model was developed by using data mining, life cycle cost analysis, real option valuation, and Monte Carlo simulation. The database were established with 437 multi-family housing complexes (MFHCs), including 116 BEER-certified MFHCs and 321 non-certified MFHCs. The case study was conducted to validate the developed prediction model using 321 non-certified MFHCs, which considered 20-year life cycle. As a result, compared to the additional construction cost, the average cost saving potentials of the 1st-BEER-certified MFHCs in Groups 1, 2, and 3 were predicted to be 3.77%, 2.78%, and 2.87%, respectively. The cost saving potentials can be used as a guideline for the additional construction cost of the BEER-certification in the early design phase.

  8. Advances in Development of Antimicrobial Peptidomimetics as Potential Drugs.

    Science.gov (United States)

    Molchanova, Natalia; Hansen, Paul R; Franzyk, Henrik

    2017-08-29

    The rapid emergence of multidrug-resistant pathogens has evolved into a global health problem as current treatment options are failing for infections caused by pan-resistant bacteria. Hence, novel antibiotics are in high demand, and for this reason antimicrobial peptides (AMPs) have attracted considerable interest, since they often show broad-spectrum activity, fast killing and high cell selectivity. However, the therapeutic potential of natural AMPs is limited by their short plasma half-life. Antimicrobial peptidomimetics mimic the structure and biological activity of AMPs, but display extended stability in the presence of biological matrices. In the present review, focus is on the developments reported in the last decade with respect to their design, synthesis, antimicrobial activity, cytotoxic side effects as well as their potential applications as anti-infective agents. Specifically, only peptidomimetics with a modular structure of residues connected via amide linkages will be discussed. These comprise the classes of α-peptoids ( N -alkylated glycine oligomers), β-peptoids ( N -alkylated β-alanine oligomers), β³-peptides, α/β³-peptides, α-peptide/β-peptoid hybrids, α/γ N -acylated N -aminoethylpeptides (AApeptides), and oligoacyllysines (OAKs). Such peptidomimetics are of particular interest due to their potent antimicrobial activity, versatile design, and convenient optimization via assembly by standard solid-phase procedures.

  9. Development of a machine learning potential for graphene

    Science.gov (United States)

    Rowe, Patrick; Csányi, Gábor; Alfè, Dario; Michaelides, Angelos

    2018-02-01

    We present an accurate interatomic potential for graphene, constructed using the Gaussian approximation potential (GAP) machine learning methodology. This GAP model obtains a faithful representation of a density functional theory (DFT) potential energy surface, facilitating highly accurate (approaching the accuracy of ab initio methods) molecular dynamics simulations. This is achieved at a computational cost which is orders of magnitude lower than that of comparable calculations which directly invoke electronic structure methods. We evaluate the accuracy of our machine learning model alongside that of a number of popular empirical and bond-order potentials, using both experimental and ab initio data as references. We find that whilst significant discrepancies exist between the empirical interatomic potentials and the reference data—and amongst the empirical potentials themselves—the machine learning model introduced here provides exemplary performance in all of the tested areas. The calculated properties include: graphene phonon dispersion curves at 0 K (which we predict with sub-meV accuracy), phonon spectra at finite temperature, in-plane thermal expansion up to 2500 K as compared to NPT ab initio molecular dynamics simulations and a comparison of the thermally induced dispersion of graphene Raman bands to experimental observations. We have made our potential freely available online at [http://www.libatoms.org].

  10. Surface and zeta-potentials of silver halide single crystals: pH-dependence in comparison to particle systems

    International Nuclear Information System (INIS)

    Selmani, Atiða; Kallay, Nikola; Preočanin, Tajana; Lützenkirchen, Johannes

    2014-01-01

    We have carried out surface and zeta-potential measurements on AgCl and AgBr single crystals. As for particle systems we find that, surprisingly and previously unnoted, the zeta-potential exhibits pH-dependence, while the surface potential does not. A possible interpretation of these observations is the involvement of water ions in the interfacial equilibria and in particular, stronger affinity of the hydroxide ion compared to the proton. The pH-dependence of the zeta-potential can be suppressed at sufficiently high silver concentrations, which agrees with previous measurements in particle systems where no pH-dependence was found at high halide ion concentrations. The results suggest a subtle interplay between the surface potential determining the halide and silver ion concentrations, and the water ions. Whenever the charge due to the halide and silver ions is sufficiently high, the influence of the proton/hydroxide ion on the zeta-potential vanishes. This might be related to the water structuring at the relevant interfaces which should be strongly affected by the surface potential. Another interesting observation is accentuation of the assumed water ion effect on the zeta-potential at the flat single crystal surfaces compared to the corresponding silver halide colloids. Previous generic MD simulations have indeed predicted that hydroxide ion adsorption is accentuated on flat/rigid surfaces. A thermodynamic model for AgI single crystals was developed to describe the combined effects of iodide, silver and water ions, based on two independently previously published models for AgI (that only consider constituent and background electrolyte ions) and inert surfaces (that only consider water and background electrolyte ions). The combined model correctly predicts all the experimentally observed trends. (paper)

  11. Development and exploration of potential routes of discovery of new superconductors

    Energy Technology Data Exchange (ETDEWEB)

    Lin, Xiao [Iowa State Univ., Ames, IA (United States)

    2013-01-01

    This thesis summarizes our efforts to develop and explore potential routes for the discovery of new superconductors. The development of viable solutions for sulfur-bearing compounds is presented. It also provides the details of searching for quantum critical points (QCPs) and possible superconductors by suppressing ferromagnetic states via chemical substitution and the application of pressure. The ferromagnetism in La(VxCr1-x)Ge3 was successfully suppressed by pressure, and, in addition, a potential QCP at ambient pressure was discovered for x = 0.16. On the other hand, the La(VxCr1-x)Sb3 series is likely to evolve into new magnetic state with V-substitution with the Cr-based magnetism appearing to be more local-moment like than for the case of LaCrGe3. We also performed detailed characterization on BaSn5 superconductor, giving further understanding of its superconducting state, and on R3Ni2-xSn7 and RNi1-xBi2±y series putting to rest spurious claims of superconductivity.

  12. Development of innovative potential of the region as a way to increase Russian economy competitiveness in today's realities

    Directory of Open Access Journals (Sweden)

    Yamkova S. P.

    2016-04-01

    Full Text Available the article explains the importance of the development of innovation as the economic competitiveness of regions of Russia. Considered term innovation potential of the region. The problems of development of innovative potential of the region and ways to solve them.

  13. Regional Entrepreneurship System: Development Parameters and Potential of Reconfiguration

    Directory of Open Access Journals (Sweden)

    Natalya Zinovyevna Solodilova

    2017-12-01

    Full Text Available The article deals with the development of entrepreneurship in the Russian regions. Firstly, the state of both Russian entrepreneurship, in general, and small and medium-sized business in particular is not satisfactory. Secondly, the measures implemented by the state in the field of entrepreneurship development are not sufficiently effective. To the authors’ opinion, these two facts are due, among other things, to a lack of a holistic understanding of what constitutes an institution of entrepreneurship in a spatial context. The authors propose to consider the development of regional entrepreneurship using the system approach with the scope to the regional business system. Within the proposed authors’ approach, resources, economic agents and institutions are considered as the main elements of this system. The authors substantiate that there are institutional configurations, and not simple institutions, which determine the parameters of interaction between the elements of the regional enterprise system. These elements can contribute to the enterprise processes in the territory or block them. We assume that even a region with an essential resource of business potential is not able to realize it completely until it develops an effective institutional configuration of the regional business system. In order to investigate certain parameters of the institutional configuration of the regional business system, we propose a methodology for assessing the institutional loyalty of business entities and testing this technique on the example of eighty-four constituent entities of the Russian Federation. We have concluded that, in a large part of the Russian regions, a successful implementation of strategy for the development of small and medium-sized businesses will require the transformation of the regional enterprise system on the basis of reengineering. It involves a radical redesigning the entire system, ensuring the entrepreneurial processes in a

  14. Identifying factors for optimal development of health-related websites: a delphi study among experts and potential future users.

    Science.gov (United States)

    Schneider, Francine; van Osch, Liesbeth; de Vries, Hein

    2012-02-14

    The Internet has become a popular medium for offering tailored and targeted health promotion programs to the general public. However, suboptimal levels of program use in the target population limit the public health impact of these programs. Optimizing program development is considered as one of the main processes to increase usage rates. To distinguish factors potentially related to optimal development of health-related websites by involving both experts and potential users. By considering and incorporating the opinions of experts and potential users in the development process, involvement in the program is expected to increase, consequently resulting in increased appreciation, lower levels of attrition, and higher levels of sustained use. We conducted a systematic three-round Delphi study through the Internet. Both national and international experts (from the fields of health promotion, health psychology, e-communication, and technical Web design) and potential users were invited via email to participate. During this study an extensive list of factors potentially related to optimal development of health-related websites was identified, by focusing on factors related to layout, general and risk information provision, questionnaire use, additional services, and ease of use. Furthermore, we assessed the extent to which experts and potential users agreed on the importance of these factors. Differences as well as similarities among experts and potentials users were deduced. In total, 20 of 62 contacted experts participated in the first round (32% response rate); 60 of 200 contacted experts (30% response rate) and 210 potential users (95% response rate) completed the second-round questionnaire, and 32 of 60 contacted experts completed the third round (53% response rate). Results revealed important factors consented upon by experts and potential users (eg, ease of use, clear structure, and detailed health information provision), as well as differences regarding

  15. Development of an EAM potential for simulation of radiation damage in Fe-Cr alloys

    Energy Technology Data Exchange (ETDEWEB)

    Wallenius, J.; Abrikosov, I.A.; Chakarova, R.; Lagerstedt, C. E-mail: christina@neutron.kth.se; Malerba, L.; Olsson, P.; Pontikis, V.; Sandberg, N.; Terentyev, D

    2004-08-01

    We have developed a set of EAM potentials for simulation of Fe-Cr alloys. By relaxing the requirement of reproducing the pressure-volume relation at short distances and by fitting to the thermal expansion coefficients of Fe and Cr, stability of the <1 1 0> self-interstitial could be obtained. For Cr, properties of the paramagnetic state were applied, providing a positive Cauchy pressure. Mixed Fe-Cr pair potentials were fitted to the calculated mixing enthalpy of ferromagnetic Fe-Cr. Simulation of thermal ageing in Fe-Cr alloys using the Fe-20Cr potential exhibited pronounced Cr-precipitation for temperatures below 900 K, a feature not observed at any temperature using a potential fitted to the mixing enthalpy of Fe-5Cr.

  16. Four essays on offshore wind power potential, development, regulatory framework, and integration

    Science.gov (United States)

    Dhanju, Amardeep

    Offshore wind power is an energy resource whose potential in the US has been recognized only recently. There is now growing interest among the coastal states to harness the resource, particularly in states adjacent to the Mid-Atlantic Bight where the shallow continental shelf allows installation of wind turbines using the existing foundation technology. But the promise of bountiful clean energy from offshore wind could be delayed or forestalled due to policy and regulatory challenges. This dissertation is an effort to identify and address some of the important challenges. Focusing on Delaware as a case study it calculates the extent of the wind resource; considers one means to facilitate resource development---the establishment of statewide and regional public power authorities; analyzes possible regulatory frameworks to manage the resource in state-controlled waters; and assesses the use of distributed storage to manage intermittent output from wind turbines. In order to cover a diversity of topics, this research uses a multi-paper format with four essays forming the body of work. The first essay lays out an accessible methodology to calculate offshore wind resource potential using publicly available data, and uses this methodology to access wind resources off Delaware. The assessment suggests a wind resource approximately four times the average electrical load in Delaware. The second essay examines the potential role of a power authority, a quasi-public institution, in lowering the cost of capital, reducing financial risk of developing and operating a wind farm, and enhancing regional collaboration on resource development and management issues. The analysis suggests that a power authority can lower the cost of offshore wind power by as much as 1/3, thereby preserving the ability to pursue cost-competitive development even if the current federal incentives are removed. The third essay addresses the existing regulatory void in state-controlled waters of Delaware

  17. Automatic electromagnetic valve for previous vacuum

    International Nuclear Information System (INIS)

    Granados, C. E.; Martin, F.

    1959-01-01

    A valve which permits the maintenance of an installation vacuum when electric current fails is described. It also lets the air in the previous vacuum bomb to prevent the oil ascending in the vacuum tubes. (Author)

  18. Recurrent severe invasive pneumococcal disease in an adult with previously unknown hyposplenia

    DEFF Research Database (Denmark)

    Ballegaard, Vibe C; Schejbel, Lone; Hoffmann, Steen

    2015-01-01

    was found. Despite immunization against S. pneumoniae and measurement of what was interpreted as protective levels of serotype-specific IgG antibodies after vaccination, the patient suffered from a third episode of IPD. CONCLUSIONS: Individuals with predisposing medical conditions or a history of severe......BACKGROUND: The risk of life-threatening and invasive infections with encapsulated bacteria is increased in patients with hyposplenia or asplenia. We report a case of recurrent invasive pneumococcal meningitis in a woman with previous unknown hyposplenia. She was vaccinated after the first episode...... of meningitis and developed sufficient levels of pneumococcal antibodies. The pneumococcal strains isolated were serotype 7 F and 17 F. To our knowledge, there has been no previously reported case of recurrent invasive pneumococcal disease in a pneumococcal vaccinated adult with hyposplenia and apparently...

  19. Ontogenetic development of the inner ear saccule and utricle in the Lusitanian toadfish: Potential implications for auditory sensitivity.

    Science.gov (United States)

    Chaves, Patrícia P; Valdoria, Ciara M C; Amorim, M Clara P; Vasconcelos, Raquel O

    2017-09-01

    Studies addressing structure-function relationships of the fish auditory system during development are sparse compared to other taxa. The Batrachoididae has become an important group to investigate mechanisms of auditory plasticity and evolution of auditory-vocal systems. A recent study reported ontogenetic improvements in the inner ear saccule sensitivity of the Lusitanian toadfish, Halobatrachus didactylus, but whether this results from changes in the sensory morphology remains unknown. We investigated how the macula and organization of auditory receptors in the saccule and utricle change during growth in this species. Inner ear sensory epithelia were removed from the end organs of previously PFA-fixed specimens, from non-vocal posthatch fry (23 cm). Epithelia were phalloidin-stained and analysed for area, shape, number and orientation patterns of hair cells (HC), and number and size of saccular supporting cells (SC). Saccular macula area expanded 41x in total, and significantly more (relative to body length) among vocal juveniles (2.3-2.9 cm). Saccular HC number increased 25x but HC density decreased, suggesting that HC addition is slower relative to epithelial growth. While SC density decreased, SC apical area increased, contributing to the epithelial expansion. The utricule revealed increased HC density (striolar region) and less epithelial expansion (5x) with growth, contrasting with the saccule that may have a different developmental pattern due to its larger size and main auditory functions. Both macula shape and HC orientation patterns were already established in the posthatch fry and retained throughout growth in both end organs. We suggest that previously reported ontogenetic improvements in saccular sensitivity might be associated with changes in HC number (not density), size and/or molecular mechanisms controlling HC sensitivity. This is one of the first studies investigating the ontogenetic development of the saccule and utricle in a vocal fish and

  20. Exploring the Poverty Reduction Potential of Social Marketing in Tourism Development

    Directory of Open Access Journals (Sweden)

    Dao V. Truong

    2015-12-01

    Full Text Available Although social marketing has been demonstrated to be an effective tool of behavior change in a variety of contexts, its poverty reduction potential in tourism development has captured limited research attention. This paper explores the potential contribution of social marketing to tourism-related poverty alleviation in Sapa, Vietnam. It does so by creating an understanding of how local residents perceive poverty, then exploring whether social marketing could be a potential solution in the case of Sapa. Through participant observations and semi-structured interviews, this study reveals that local people perceive poverty as a lack of rice and/or income and ascribe it to both internal and external factors. Local women often follow tourists to sell handicrafts, causing discomfort for tourists and driving them away from certain destinations. Insufficient capital and farming land are also identified as a critical barrier to poverty reduction. This study argues that by understanding the poor people’s perspectives on poverty, we can identify meaningful approaches to poverty alleviation. Thereby, social marketing can be one of the tools to bring the marginalized voice of poor people to the attention of decision-makers.

  1. Wood energy in Switzerland - State of the art, developments and potential

    International Nuclear Information System (INIS)

    Rutschmann, C.

    2006-01-01

    This article reviews the present-day use of wood as a source of energy and the potential it exhibits as part of a future Swiss energy supply system. The history of the use of wood to provide energy is looked at and its changing share of total energy consumption is commented on. In particular, the use of wood energy during the period 1991-2004 is looked at and its promotion by various programmes examined. Apart from wood-fired heating systems, open fires are commented on as are the changes noted over this period in the types of heating systems installed. The potential of wood-energy and custom-tailored solutions are looked at. The important role played by quality assurance for fast market development is stressed. Finally, the role to be played by wood energy in the future is looked at

  2. Mapping industrial networks as an approach to identify inter-organisational collaborative potential in new product development

    DEFF Research Database (Denmark)

    Parraguez, Pedro; Maier, Anja

    2012-01-01

    . Consequently, identifying and selecting potential partners to establish collaboration agreements can be a key activity in the new product development process. This paper explores the implications of mapping industrial networks with the purpose of identifying inter-organisational collaborative potential...

  3. Geographical Information Systems Assessment of Development Disparities Among Romanian Regions of Development

    Directory of Open Access Journals (Sweden)

    SORIN DANIEL MANOLE

    2012-01-01

    Full Text Available New strategies of the European Union, focused directly on regional development or originated from different areas, but leading to changes in this field, had resulted into a set of indices used to monitor the effects of their implementation. Previous studies suggest that flexible systems perform better and could strengthen the administrative capacity of accessing structural and cohesion funds. Our study used the Geographical Information Systems (GIS to produce hierarchies of the territorial indices at NUTS level II, displayed as charts and maps underlining the disparities between the socioeconomic, cultural and environmental aspects of the development. The results suggest that the regions with a low potential of development are situated in the south of Romania, but, most important, underline the potential of the method to be used as a planning tool in regional development, as its flexibility allows for an input with particular focus from different stakeholders, resulting into the selection of different indices and weights.

  4. Delineation of groundwater development potential zones in parts of marginal Ganga Alluvial Plain in South Bihar, Eastern India.

    Science.gov (United States)

    Saha, Dipankar; Dhar, Y R; Vittala, S S

    2010-06-01

    A part of the Gangetic Alluvial Plain covering 2,228 km(2), in the state of Bihar, is studied for demarcating groundwater development potential zones. The area is mainly agrarian and experiencing intensive groundwater draft to the tune of 0.12 million cubic metre per square kilometres per year from the Quaternary marginal alluvial deposits, unconformably overlain northerly sloping Precambrian bedrock. Multiparametric data on groundwater comprising water level, hydraulic gradient (pre- and post-monsoon), aquifer thickness, permeability, suitability of groundwater for drinking and irrigation and groundwater resources vs. draft are spatially analysed and integrated on a Geographical Information System platform to generate thematic layers. By integrating these layers, three zones have been delineated based on groundwater development potential. It is inferred that about 48% of the area covering northern part has high development potential, while medium and low development potential category covers 41% of the area. Further increase in groundwater extraction is not recommended for an area of 173 km(2), affected by over-exploitation. The replenishable groundwater resource available for further extraction has been estimated. The development potential enhances towards north with increase in thickness of sediments. Local deviations are due to variation of-(1) cumulative thickness of aquifers, (2) deeper water level resulting from localised heavy groundwater extraction and (3) aquifer permeability.

  5. Migratory Behavior and Physiological Development as Potential Determinants of Life History Diversity in Fall Chinook Salmon in the Clearwater River

    Energy Technology Data Exchange (ETDEWEB)

    Tiffan, Kenneth F. [U.S. Geological Survey, Western Fisheries Research Center, 5501-A Cook-Underwood Road Cook Washington 98605 USA; Kock, Tobias J. [U.S. Geological Survey, Western Fisheries Research Center, 5501-A Cook-Underwood Road Cook Washington 98605 USA; Connor, William P. [U.S. Fish and Wildlife Service, Idaho Fishery Resource Office, Post Office Box 18 Ahsahka Idaho 81530 USA; Richmond, Marshall C. [Pacific Northwest National Laboratory, Post Office Box 999 Richland Washington 99352 USA; Perkins, William A. [Pacific Northwest National Laboratory, Post Office Box 999 Richland Washington 99352 USA

    2018-03-01

    We studied the influence of behavior, water velocity, and physiological development on the downstream movement of subyearling fall Chinook Salmon Oncorhynchus tshawytscha in free-flowing and impounded reaches of the Clearwater and Snake rivers as potential mechanisms that might explain life history diversity in this stock. Movement rates and the percentage of radio-tagged fish that moved faster than the average current velocity were highest in the free-flowing Clearwater River compared to impounded reaches. This provided support for our hypothesis that water velocity is a primary determinant of downstream movement regardless of a fish’s physiological development. In contrast, movement rates slowed and detections became fewer in impounded reaches where velocities were much lower. The percentage of fish that moved faster than the average current velocity continued to decline and reached zero in the lower-most reach of Lower Granite Reservoir suggesting that behavioral disposition to move downstream was low. These findings contrast those of a similar, previous study of Snake River subyearlings in spite of hydrodynamic conditions being similar. Physiological differences between Snake and Clearwater river migrants shed light on this disparity. Subyearlings from the Clearwater River were parr-like in their development and never showed an increase in gill Na+/K+-ATPase activity as did smolts from the Snake River. The later emergence timing and cooler rearing temperatures in the Clearwater River may suppress normal physiological development that causes many fish to delay downstream movement and adopt a yearling life history strategy.

  6. Potential development of an intercity passenger transit system in Texas : final project report.

    Science.gov (United States)

    2010-05-01

    This report describes the findings of a research study of the potential for development of an intercity rail and : express bus system in the state of Texas. Rather than focus on regional commuter or light rail systems : radiating from urban areas, th...

  7. Managing Virtual Product Development team: A Review

    Directory of Open Access Journals (Sweden)

    Amir Mohammad Colabi

    2014-05-01

    Full Text Available Although there are many potential benefits associated with the use of virtual product development teams, exploiting these benefits requires an appropriate management. Managing virtual product development team is a critical issue as many of these teams fail to accomplish their goals. Review of previous literature shows that body of knowledge in managing virtual product development teams is fragmented and inconsistent. The main objective of this paper is to categorize the previous research on the subject of virtual product development team management in order to integrate the research into a thematic model and to enable recommendations for future research. So, this study reviews and summarizes empirical research in the field, also conceptual and qualitative papers, experiences, reports and explorative case studies. Results show that there are three fields of research in this area, including: Virtual production and Virtual team in Product Development, Managing virtual team in R&D[1] and product development, Managing global virtual product development teams. In order to organize previous studies in this area, a thematic map is proposed which shows the structure and sequence of research. Finally, a comprehensive discussion on the future directions in this field is proposed.

  8. Occupational Exposure to Antineoplastic Drugs: Identification of Job Categories Potentially Exposed throughout the Hospital Medication System

    Directory of Open Access Journals (Sweden)

    Chun-Yip Hon

    2011-09-01

    Conclusion: We found drug contamination on select surfaces at every stage of the medication system, which indicates the existence of an exposure potential throughout the facility. Our results suggest that a broader range of workers are potentially exposed than has been previously examined. These results will allow us to develop a more inclusive exposure assessment encompassing all healthcare workers that are at risk throughout the hospital medication system.

  9. Residents’ Attitudes towards Sustainable Tourism Development in a Historical-Cultural Village: Influence of Perceived Impacts, Sense of Place and Tourism Development Potential

    OpenAIRE

    He Zhu; Jiaming Liu; Zongcai Wei; Weiheng Li; Lei Wang

    2017-01-01

    This study aims to assess the residents’ support for sustainable tourism development in a destination that is in the initial tourism development stage. Residents’ perception of sustainable tourism development potential, sense of place, perceived tourism impacts, and tourism development support were involved in this study. A total of 331 completed questionnaire surveys were collected in Luozhou, a historical-cultural village in China. The empirical data were analyzed using a structural equatio...

  10. Spectrophotometric determination of uranium with arsenazo previous liquid-liquid extraction and colour development in organic medium

    International Nuclear Information System (INIS)

    Palomares Delgado, F.; Vera Palomino, J.; Petrement Eguiluz, J. C.

    1964-01-01

    The determination of uranium with arsenazo is hindered by a great number of cation which form stable complexes with the reactive and may given rise to serious interferences. By studying the optimum conditions of uranium the extraction be means of tributylphosphate solutions dissolved in methylisobuthylketone, under conditions for previous masking of the interfering cations, an organic extract was obtained containing all the uranium together with small amounts of iron. The possible interference derived from the latter element is avoided by reduction with hydroxylammoniumchlorid followed by complex formation of the Fe(II)-ortophenantroline compound in alcoholic medium. (Author) 17 refs

  11. Response to deep TMS in depressive patients with previous electroconvulsive treatment.

    Science.gov (United States)

    Rosenberg, Oded; Zangen, Abraham; Stryjer, Rafael; Kotler, Moshe; Dannon, Pinhas N

    2010-10-01

    The efficacy of transcranial magnetic stimulation (TMS) in the treatment of major depression has already been shown. Novel TMS coils allowing stimulation of deeper brain regions have recently been developed and studied. Our study is aimed at exploring the possible efficacy of deep TMS in patients with resistant depression, who previously underwent electroconvalsive therapy (ECT). Using Brainsway's deep TMS H1 coil, six patients who previously underwent ECT, were treated with 120% power of the motor threshold at a frequency of 20 Hz. Patients underwent five sessions per week, up to 4 weeks. Before the study, patients were evaluated using the Hamilton depression rating scale (HDRS, 24 items), the Hamilton anxiety scale, and the Beck depression inventory and were again evaluated after 5, 10, 15, and 20 daily treatments. Response to treatment was considered a reduction in the HDRS of at least 50%, and remission was considered a reduction of the HDRS-24 below 10 points. Two of six patients responded to the treatment with deep TMS, including one who achieved full remission. Our results suggest the possibility of a subpopulation of depressed patients who may benefit from deep TMS treatment, including patients who did not respond to ECT previously. However, the power of the study is small and similar larger samples are needed. Copyright © 2010 Elsevier Inc. All rights reserved.

  12. THEORY OF GENERATIONS AS A TOOL FOR ANALYSIS, FORMATION AND DEVELOPMENT OF LABOUR POTENTIAL

    Directory of Open Access Journals (Sweden)

    I. M. Gurova

    2016-01-01

    Full Text Available The modern Strauss–Howe generational theory created at the intersection of economic, sociological, historical and psychological Sciences. She focuses primarily on difference of attitudes of generations, due to the specific social environment, corresponding to a certain period of time. Such a perspective on issues related to the human factor in the economy, has recently attracted interest not only from researchers, but also finds application for solving practical problems in some fields of business.Subject / theme. The article is devoted to one of the urgent contemporary socio-economic problems – the issue of the formation and development of labor potential. In this context, the theory of generations is offered by the authors as a tool for the study of qualitative parameters of human resources and the planning of future work opportunities in our country. In particular, the article considers the main aspects of the classical version of the Strauss–Howe generational theory and its Russian adaptation. Statistics describing the General demographics and working population of Russia from the point of view of generational groups. On this basis, a forecast is made of the labor potential of the country in the long term structure, review and compare the basic values and business characteristics of its constituent generations. Problem areas for which use of generational approach is rational are revealed and the corresponding recommendations are made.Objectives. The purpose of this article is justification of the possible application of provisions of modern theories of generations to identify and predict the dynamics of qualitative characteristics of the domestic workforce, as well as the prospects of its use in order to control the formation and development of labor potential.Methods. Methodological basis of the presented work make comparative and economic-statistical and socio-cultural methods of analysis.Results. In the framework of this article

  13. Rapid mineralisation of the herbicide isoproturon in soil from a previously treated Danish agricultural field.

    Science.gov (United States)

    Sørensen, Sebastian R; Aamand, Jens

    2003-10-01

    Mineralisation of the phenylurea herbicide isoproturon (3-(4-isopropylphenyl)-1,1-dimethylurea) and two of its known metabolites, 3-(4-isopropylphenyl)-1-methylurea (monodesmethyl-isoproturon) and 4-isopropylaniline, was studied in Danish agricultural soils with or without previous exposure to isoproturon. A potential for rapid mineralisation of isoproturon and the two metabolites was present in soils sampled from three plots within an agricultural field previously treated regularly with the herbicide, with 34-45%, 51-58% and 33-36% of the added [phenyl-U-14C]isoproturon, [phenyl-U-14C]monodesmethyl-isoproturon and [phenyl-U-14C]4-isopropylaniline metabolised to [14C]carbon dioxide within 30 days at 20 degrees C. In contrast, such extensive mineralisation of these three compounds was not observed within this period in soils sampled from two other agricultural fields without previous treatment with isoproturon. The mineralisation patterns indicated growth-linked metabolism of the three compounds in the previously exposed soils, and doubling times for [14C]carbon dioxide production ranged from 1.6 to 3.2, 1.0 to 2.1 and 1.3 to 1.7 days for isoproturon, monodesmethyl-isoproturon and 4-isopropylaniline, respectively. The ability to mineralise [phenyl-U-14C]isoproturon to [14C]carbon dioxide was successfully sub-cultured to a fresh mineral medium which provided isoproturon as sole source of carbon and nitrogen. One of the soils sampled from an agricultural field not previously treated with isoproturon showed accelerated mineralisation of [phenyl-U-14C]4-isopropylaniline toward the end of the experiment, with a doubling time for [14C]carbon dioxide production of 7.4days. This study indicates that the occurrence of rapid mineralisation of the phenyl ring of isoproturon to carbon dioxide is related to previous exposure to the herbicide, which suggests that microbial adaptation upon repeated isoproturon use may occur within agricultural fields.

  14. Miscellaneous conditions and future potential

    International Nuclear Information System (INIS)

    Berquist, T.H.; Ehman, R.L.; Richardson, M.L.; Helms, C.A.

    1987-01-01

    The previous chapters have discussed basic principles and the types of musculoskeletal pathology that have been most extensively studied with magnetic resonance (MR) techniques. MR has also demonstrated significant potential in other areas, but experience is more limited. Despite this limited experience, the potential application of MR imaging in these areas is discussed in this paper

  15. DOE Research and Development Accomplishments Previous Highlights

    Science.gov (United States)

    through his Nobel Lecture in 1961, about unraveling the secrets of photosynthesis -- the process by which . March 10, 2015 Twenty years ago, the top quark was first observed in experiments at the Tevatron proton sophisticated detectors, the top was hard to find. After a top is made from a proton-antiproton collision, a

  16. The potential for developing a tactile communication system based on Blissymbolics.

    Science.gov (United States)

    Isaacson, Mick D; Lloyd, Lyle L

    2015-02-01

    To be useful for tactile communication, tactile stimuli need to be discriminable from each other. The objective of this study was to determine whether raised-line renderings of Blissymbols have the capacity for being developed into a tactile communication system as measured by their tactile discriminability. Tactile discrimination of Blissymbols was measured by performance on a task in which participants were asked to feel a target raised-line Blissymbol and then to find the target within an array containing the target and raised-line Blissymbol foils. The vast majority of tactile Blissymbols had tactile discrimination scores of 90% accuracy or better. Most raised-line Blissymbols can be tactilely discriminated from each other, indicating that they have the potential for being developed into a tactile communication system.

  17. Development of the Damage Potential resulting from Avalanche Risks, Case Study Galtür (Tyrol, Austria)

    Science.gov (United States)

    Keiler, M.

    2003-04-01

    Reports on catastrophes with high damage caused by natural hazards seem to have increased in number recently. A new trend in dealing with these natural processes leads to the integration of risk into natural hazards evaluations and approaches of integral risk management. The risk resulting from natural hazards can be derived from the combination of parameters of physical processes (intensity and recurrence probability) and damage potential (probability of presence and expected damage value). Natural hazard research focuses mainly on the examination, modelling and estimation of individual geomorphological processes as well as on future developments caused by climate change. Even though damage potential has been taken into account more frequently, quantifying statements are still missing. Due to the changes of the socio-economic structures in mountain regions (urban sprawl, population growth, increased mobility and tourism) these studies are mandatory. This study presents a conceptual method that records the damage potential (probability of physical presence, evaluation of buildings) and shows the development of the damage potential resulting from avalanches since 1950. The study area is the community of Galtür, Austria. 36 percent of the existing buildings are found in officially declared avalanche hazard zones. The majority of these buildings are either agricultural or accommodation facilities. Additionally, the effects of physical planning and/or technical measures on the spatial development of the potential damage are illustrated. The results serve to improve risk determination and point out an unnoticed increase of damage potential and risk in apparently safe settlement areas.

  18. Secukinumab for rheumatology: development and its potential place in therapy

    Directory of Open Access Journals (Sweden)

    Koenders MI

    2016-06-01

    Full Text Available Marije I Koenders, Wim B van den Berg Experimental Rheumatology, Radboud University Medical Center, Nijmegen, the Netherlands Abstract: Rheumatic disease is not a single disorder, but a group of more than 100 diseases that affect joints, connective tissues, and/or internal organs. Although rheumatic diseases like rheumatoid arthritis (RA, psoriatic arthritis, and ankylosing spondylitis (AS differ in their pathogenesis and clinical presentation, the treatment of these inflammatory disorders overlaps. Non-steroid anti-inflammatory drugs are used to reduce pain and inflammation. Additional disease-modifying anti-rheumatic drugs are prescribed to slowdown disease progression, and is in RA more frequently and effectively applied than in AS. Biologicals are a relatively new class of treatments that specifically target cytokines or cells of the immune system, like tumor necrosis factor alpha inhibitors or B-cell blockers. A new kid on the block is the interleukin-17 (IL-17 inhibitor secukinumab, which has been recently approved by the US Food and Drug Administration for moderate-to-severe plaque psoriasis, psoriatic arthritis, and AS. IL-17 is a proinflammatory cytokine that has an important role in host defense, but its proinflammatory and destructive effects have also been linked to pathogenic processes in autoimmune diseases like RA and psoriasis. Animal models have greatly contributed to further insights in the potential of IL-17 blockade in autoimmune and autoinflammatory diseases, and have resulted in the development of various potential drugs targeting the IL-17 pathway. Secukinumab (AIN457 is a fully human monoclonal antibody that selectively binds to IL-17A and recently entered the market under the brand name Cosentyx®. By binding to IL-17A, secukinumab prevents it from binding to its receptor and inhibits its ability to trigger inflammatory responses that play a role in the development of various autoimmune diseases. With secukinumab being

  19. Developing estimates of potential demand for renewable wood energy products in Alaska

    Science.gov (United States)

    Allen M. Brackley; Valerie A. Barber; Cassie Pinkel

    2010-01-01

    Goal three of the current U.S. Department of Agriculture, Forest Service strategy for improving the use of woody biomass is to help develop and expand markets for woody biomass products. This report is concerned with the existing volumes of renewable wood energy products (RWEP) that are currently used in Alaska and the potential demand for RWEP for residential and...

  20. EDUCATIONAL POTENTIAL OF DEVELOPMENT: INTERNATIONAL COMPARISONS ON THE BASIS OF STATISTICAL INDICATORS

    Directory of Open Access Journals (Sweden)

    S. Bychkova

    2014-04-01

    Full Text Available Using information WEF, UNDP, OECD investigated differences in the characteristics of education as a factor of competitiveness and level of development of countries, formed the group of OECD countries and their partners, significantly differ in indicators of education, studied Russian position among OECD countries and BRICS, formulated conclusions about ways of improving the educational potential of the country

  1. Regenerative Potential of Ependymal Cells for Spinal Cord Injuries Over Time

    Directory of Open Access Journals (Sweden)

    Xiaofei Li

    2016-11-01

    Full Text Available Stem cells have a high therapeutic potential for the treatment of spinal cord injury (SCI. We have shown previously that endogenous stem cell potential is confined to ependymal cells in the adult spinal cord which could be targeted for non-invasive SCI therapy. However, ependymal cells are an understudied cell population. Taking advantage of transgenic lines, we characterize the appearance and potential of ependymal cells during development. We show that spinal cord stem cell potential in vitro is contained within these cells by birth. Moreover, juvenile cultures generate more neurospheres and more oligodendrocytes than adult ones. Interestingly, juvenile ependymal cells in vivo contribute to glial scar formation after severe but not mild SCI, due to a more effective sealing of the lesion by other glial cells. This study highlights the importance of the age-dependent potential of stem cells and post-SCI environment in order to utilize ependymal cell's regenerative potential.

  2. Development of Comparative Toxicity Potentials of TiO2 Nanoparticles for Use in Life Cycle Assessment

    DEFF Research Database (Denmark)

    Ettrup, Kim; Kounina, Anna; Hansen, Steffen Foss

    2017-01-01

    for TiO2 nanoparticles (TiO2-NP) for use in LCA. We adapted the USEtox 2.0 consensus model to integrate the SimpleBox4Nano fate model, and we populated the resulting model with TiO2-NP specific data. We thus calculated CTP values for TiO2 nanoparticles for air, water, and soil emission compartments...... in earlier studies. Assumptions, which were performed in those previous studies because of lack of data and knowledge at the time they were made, primarily explain such discrepancies. For future assessment of potential toxic impacts of TiO2 nanoparticles in LCA studies, we therefore recommend the use of our......Studies have shown that releases of nanoparticles may take place through the life cycle of products embedding nanomaterials, thus resulting in potential impacts on ecosystems and human health. While several life cycle assessment (LCA) studies have assessed such products, only a few of them have...

  3. Development of an Improved Methodology to Assess Potential Unconventional Gas Resources

    International Nuclear Information System (INIS)

    Salazar, Jesus; McVay, Duane A.; Lee, W. John

    2010-01-01

    Considering the important role played today by unconventional gas resources in North America and their enormous potential for the future around the world, it is vital to both policy makers and industry that the volumes of these resources and the impact of technology on these resources be assessed. To provide for optimal decision making regarding energy policy, research funding, and resource development, it is necessary to reliably quantify the uncertainty in these resource assessments. Since the 1970s, studies to assess potential unconventional gas resources have been conducted by various private and governmental agencies, the most rigorous of which was by the United States Geological Survey (USGS). The USGS employed a cell-based, probabilistic methodology which used analytical equations to calculate distributions of the resources assessed. USGS assessments have generally produced distributions for potential unconventional gas resources that, in our judgment, are unrealistically narrow for what are essentially undiscovered, untested resources. In this article, we present an improved methodology to assess potential unconventional gas resources. Our methodology is a stochastic approach that includes Monte Carlo simulation and correlation between input variables. Application of the improved methodology to the Uinta-Piceance province of Utah and Colorado with USGS data validates the means and standard deviations of resource distributions produced by the USGS methodology, but reveals that these distributions are not right skewed, as expected for a natural resource. Our investigation indicates that the unrealistic shape and width of the gas resource distributions are caused by the use of narrow triangular input parameter distributions. The stochastic methodology proposed here is more versatile and robust than the USGS analytic methodology. Adoption of the methodology, along with a careful examination and revision of input distributions, should allow a more realistic

  4. Identification of Color Development Potential of Quartz by Raman Spectroscopy

    International Nuclear Information System (INIS)

    Gomides Alkmim, D.; Soares Lameiras, F.

    2013-01-01

    Colorless quartz is usually exposed to ionizing radiation (gamma rays or high energy electron beams) in order to acquire different colors for jewelry. This is due to the presence of traces of some elements such as aluminum, iron, hydrogen, lithium, or sodium, which are responsible for the extrinsic colors developed after irradiation. Most quartz crystals are extracted colorless from nature and it is necessary to separate those that can develop colors from those that cannot. This can be done through irradiation tests, which take a long time. Other option is to collect the infrared signature of colorless quartz. However, infrared spectroscopic analysis is quite expensive, especially when using portable devices. Raman spectroscopy is now available as an inexpensive and portable technique that could provide identification of the samples of colorless quartz still in the field, facilitating the prediction for their economic exploitation. In addition, Raman spectroscopy usually requires a minimum or no sample preparation. This paper presents an investigation of the feasibility of using Raman spectroscopy as a substitute for infrared spectroscopy to predict the potential for color development of quartz. A band at 3595 cm -1 was observed, only along the c axis of a prasiolite excited by a high power 514 nm laser. This band was nor observed in quartz samples that do not develop color after irradiation, hence requiring further studies. (Author)

  5. Development of a potential screening measure for adolescent depression.

    Science.gov (United States)

    Taouk, Mona; Meiser, Bettina; Hadzi-Pavlovic, Dusan; Dudley, Michael; Mitchell, Philip B

    2017-06-01

    Few adolescent-specific depression screening instruments have been developed in recent years using multi-method approaches (qualitative and quantitative), and some of those available have limitations with an adolescent audience. We describe the development of a potential measure - the Taouk Scale for Adolescent Depression. Draft items were informed by findings from focus groups and reviews by adolescents and healthcare professionals, resulting in a provisional 97-item scale. This was administered to a nation-wide sample of 3087 secondary students. Exploratory factor analysis was used in a development subset to examine dimensionality of items and reduce their number, with the final item set evaluated in a validation subset. Four reliable factors - negative outlook, emotional distress, behavioural changes and cognitive and somatic disturbances - were obtained from the exploratory factor analysis, resulting in a 28-item instrument, which was corroborated by confirmatory factor analysis. The final scale includes a number of novel items not included in current measures, i.e., whether respondents wear more black clothing than usual, deliberately damage property, take more risks, 'space out' at school and are engaged in substance abuse and/or increased sexual activity. The Taouk Scale for Adolescent Depression demonstrated sound psychometric properties and may have utility for future screening and future epidemiological purposes. It appears to be a valid and reliable screening instrument for adolescent depression that includes a number of novel items. Further research is necessary to confirm its criterion validity in clinically depressed samples.

  6. Potential drug development candidates for human soil-transmitted helminthiases.

    Directory of Open Access Journals (Sweden)

    Piero Olliaro

    2011-06-01

    Full Text Available Few drugs are available for soil-transmitted helminthiasis (STH; the benzimidazoles albendazole and mebendazole are the only drugs being used for preventive chemotherapy as they can be given in one single dose with no weight adjustment. While generally safe and effective in reducing intensity of infection, they are contra-indicated in first-trimester pregnancy and have suboptimal efficacy against Trichuris trichiura. In addition, drug resistance is a threat. It is therefore important to find alternatives.We searched the literature and the animal health marketed products and pipeline for potential drug development candidates. Recently registered veterinary products offer advantages in that they have undergone extensive and rigorous animal testing, thus reducing the risk, cost and time to approval for human trials. For selected compounds, we retrieved and summarised publicly available information (through US Freedom of Information (FoI statements, European Public Assessment Reports (EPAR and published literature. Concomitantly, we developed a target product profile (TPP against which the products were compared.The paper summarizes the general findings including various classes of compounds, and more specific information on two veterinary anthelmintics (monepantel, emodepside and nitazoxanide, an antiprotozoal drug, compiled from the EMA EPAR and FDA registration files.Few of the compounds already approved for use in human or animal medicine qualify for development track decision. Fast-tracking to approval for human studies may be possible for veterinary compounds like emodepside and monepantel, but additional information remains to be acquired before an informed decision can be made.

  7. Fuel cell two wheelers: Good market potential in Shanghai and the suggestions for development. Paper no. IGEC-1-145

    International Nuclear Information System (INIS)

    Li, L.; Yu, Z.; Gong, H.

    2005-01-01

    This paper presents the feasibility and the market potential for developing the Fuel Cell two-wheelers in Asia. Shanghai is taken as one case for this analysis. Based on the study of the transportation modal, the constitute of the vehicles both motored and non-motored, the future planning for the transportation and the market potential of two-wheelers requirement and the quick development market of Battery Bicycles in Shanghai, the potential market of Fuel Cell Two-wheelers in Shanghai is predicated. The predominance in the research and development for Fuel Cell stacks, the storage for the hydrogen and the local supply ability of hydrogen of Shanghai are also introduced. The Shanghai's Fuel Cell Market potential is also presented based on the population of motorcycles at last. The suggestions for the further development of Fuel Cell two-wheelers are proposed. (author)

  8. Exploring the potential impacts of tourism development on social and ecological change in the Solomon Islands.

    Science.gov (United States)

    Diedrich, Amy; Aswani, Shankar

    2016-11-01

    Pacific Island communities may be vulnerable to negative impacts of economic development, which is often considered a strategy for reducing vulnerability to environmental change. Studies that evaluate potential impacts of economic development in isolated communities may be inaccurate to only focus on asking people to anticipate impacts of phenomena they have had minimal exposure to. We used an open-ended approach to evaluate how communities in the Solomon Islands perceived change, and used this information to anticipate potential impacts of the government's plans to develop tourism. Our results showed mostly negative expectations of change, particularly socio-cultural, which was perceived as being driven by diminishing social capital, foreign influence, and economic development. Despite minimal exposure, locals supported tourism and had more positive expectations of change associated with this activity. Our findings emphasize the need for locally appropriate planning to ensure intended positive impacts of tourism and other forms of economic development.

  9. Intralesional Osteophyte Regrowth Following Autologous Chondrocyte Implantation after Previous Treatment with Marrow Stimulation Technique.

    Science.gov (United States)

    Demange, Marco Kawamura; Minas, Tom; von Keudell, Arvind; Sodha, Sonal; Bryant, Tim; Gomoll, Andreas H

    2017-04-01

    Objective Bone marrow stimulation surgeries are frequent in the treatment of cartilage lesions. Autologous chondrocyte implantation (ACI) may be performed after failed microfracture surgery. Alterations to subchondral bone as intralesional osteophytes are commonly seen after previous microfracture and removed during ACI. There have been no reports on potential recurrence. Our purpose was to evaluate the incidence of intralesional osteophyte development in 2 cohorts: existing intralesional osteophytes and without intralesional osteophytes at the time of ACI. Study Design We identified 87 patients (157 lesions) with intralesional osteophytes among a cohort of 497 ACI patients. Osteophyte regrowth was analyzed on magnetic resonance imaging and categorized as small or large (less or more than 50% of the cartilage thickness). Twenty patients (24 defects) without intralesional osteophytes at the time of ACI acted as control. Results Osteophyte regrowth was observed in 39.5% of lesions (34.4% of small osteophytes and 5.1% of large osteophytes). In subgroup analyses, regrowth was observed in 45.8% of periosteal-covered defects and in 18.9% of collagen membrane-covered defects. Large osteophyte regrowth occurred in less than 5% in either group. Periosteal defects showed a significantly higher incidence for regrowth of small osteophytes. In the control group, intralesional osteophytes developed in 16.7% of the lesions. Conclusions Even though intralesional osteophytes may regrow after removal during ACI, most of them are small. Small osteophyte regrowth occurs almost twice in periosteum-covered ACI. Large osteophytes occur only in 5% of patients. Intralesional osteophyte formation is not significantly different in preexisting intralesional osteophytes and control groups.

  10. Effect of temperature on development and growth potential of axillary buds in roses

    NARCIS (Netherlands)

    Marcelis-van Acker, C.A.M.

    1995-01-01

    The effect of temperature during axillary bud formation on axillary bud development and subsequent shoot growth was investigated. Growth potential of the axillary buds was studied either in situ, by pruning the parent shoot above the bud, or in isolation, by grafting the bud or by culturing the bud

  11. Characterization of the Burkholderia mallei tonB Mutant and Its Potential as a Backbone Strain for Vaccine Development.

    Directory of Open Access Journals (Sweden)

    Tiffany M Mott

    Full Text Available In this study, a Burkholderia mallei tonB mutant (TMM001 deficient in iron acquisition was constructed, characterized, and evaluated for its protective properties in acute inhalational infection models of murine glanders and melioidosis.Compared to the wild-type, TMM001 exhibits slower growth kinetics, siderophore hyper-secretion and the inability to utilize heme-containing proteins as iron sources. A series of animal challenge studies showed an inverse correlation between the percentage of survival in BALB/c mice and iron-dependent TMM001 growth. Upon evaluation of TMM001 as a potential protective strain against infection, we found 100% survival following B. mallei CSM001 challenge of mice previously receiving 1.5 x 10(4 CFU of TMM001. At 21 days post-immunization, TMM001-treated animals showed significantly higher levels of B. mallei-specific IgG1, IgG2a and IgM when compared to PBS-treated controls. At 48 h post-challenge, PBS-treated controls exhibited higher levels of serum inflammatory cytokines and more severe pathological damage to target organs compared to animals receiving TMM001. In a cross-protection study of acute inhalational melioidosis with B. pseudomallei, TMM001-treated mice were significantly protected. While wild type was cleared in all B. mallei challenge studies, mice failed to clear TMM001.Although further work is needed to prevent chronic infection by TMM001 while maintaining immunogenicity, our attenuated strain demonstrates great potential as a backbone strain for future vaccine development against both glanders and melioidosis.

  12. Surveillance for previously unmonitored organic contaminants in the San Francisco Estuary.

    Science.gov (United States)

    Oros, Daniel R; Jarman, Walter M; Lowe, Theresa; David, Nicole; Lowe, Sarah; Davis, Jay A

    2003-09-01

    The San Francisco Estuary Regional Monitoring Program initiated surveillance monitoring to identify previously unmonitored synthetic organic contaminants in the San Francisco Estuary. Organic extracts of water samples were analyzed using gas chromatography-mass spectrometry in full scan mode. The major contaminant classes identified in the samples were fire retardants, pesticides, personal care product ingredients, and plasticizers. Evidence from the literature suggests that some of these contaminants can persist in the environment, induce toxicity, and accumulate in marine biota and in higher food chain consumers. The major sources of these contaminants into the marine environment are the discharge of municipal and industrial wastewater effluents, urban stormwater, and agricultural runoff. As a proactive effort, it is suggested that surveillance studies be used routinely in monitoring programs to identify and prevent potential problem contaminants from harming the marine environment.

  13. Reoperative sentinel lymph node biopsy after previous mastectomy.

    Science.gov (United States)

    Karam, Amer; Stempel, Michelle; Cody, Hiram S; Port, Elisa R

    2008-10-01

    Sentinel lymph node (SLN) biopsy is the standard of care for axillary staging in breast cancer, but many clinical scenarios questioning the validity of SLN biopsy remain. Here we describe our experience with reoperative-SLN (re-SLN) biopsy after previous mastectomy. Review of the SLN database from September 1996 to December 2007 yielded 20 procedures done in the setting of previous mastectomy. SLN biopsy was performed using radioisotope with or without blue dye injection superior to the mastectomy incision, in the skin flap in all patients. In 17 of 20 patients (85%), re-SLN biopsy was performed for local or regional recurrence after mastectomy. Re-SLN biopsy was successful in 13 of 20 patients (65%) after previous mastectomy. Of the 13 patients, 2 had positive re-SLN, and completion axillary dissection was performed, with 1 having additional positive nodes. In the 11 patients with negative re-SLN, 2 patients underwent completion axillary dissection demonstrating additional negative nodes. One patient with a negative re-SLN experienced chest wall recurrence combined with axillary recurrence 11 months after re-SLN biopsy. All others remained free of local or axillary recurrence. Re-SLN biopsy was unsuccessful in 7 of 20 patients (35%). In three of seven patients, axillary dissection was performed, yielding positive nodes in two of the three. The remaining four of seven patients all had previous modified radical mastectomy, so underwent no additional axillary surgery. In this small series, re-SLN was successful after previous mastectomy, and this procedure may play some role when axillary staging is warranted after mastectomy.

  14. Comparative analysis of countries in the peer-group based on economic potential and components of sustainable development

    Directory of Open Access Journals (Sweden)

    Sergii VOITKO

    2017-10-01

    Full Text Available The authors study levels of sustainable development potential and determine the positions of Ukraine and other countries in the peer-groups [4], based on individual macroeconomic indicators. The research includes a comparative analysis of absolute and relative terms of GDP, industrial production and the index of competitiveness for the countries included to the peer-groups. The authors analyse the position of countries based on the GDP per capita and components of sustainable development (Quality of Life Index and Security of Life Index. In the article, the authors suggest the methodical approach of performing the comparative analysis of peer-group countries based on their indicators values. This approach gives the possibility to investigate the country’s potential in the limits of the chosen peer-group and propose the recommendations for increase of economic potential in purpose of sustainable development achievement.

  15. 77 FR 70176 - Previous Participation Certification

    Science.gov (United States)

    2012-11-23

    ... participants' previous participation in government programs and ensure that the past record is acceptable prior... information is designed to be 100 percent automated and digital submission of all data and certifications is... government programs and ensure that the past record is acceptable prior to granting approval to participate...

  16. Exome sequencing of a large family identifies potential candidate genes contributing risk to bipolar disorder.

    Science.gov (United States)

    Zhang, Tianxiao; Hou, Liping; Chen, David T; McMahon, Francis J; Wang, Jen-Chyong; Rice, John P

    2018-03-01

    Bipolar disorder is a mental illness with lifetime prevalence of about 1%. Previous genetic studies have identified multiple chromosomal linkage regions and candidate genes that might be associated with bipolar disorder. The present study aimed to identify potential susceptibility variants for bipolar disorder using 6 related case samples from a four-generation family. A combination of exome sequencing and linkage analysis was performed to identify potential susceptibility variants for bipolar disorder. Our study identified a list of five potential candidate genes for bipolar disorder. Among these five genes, GRID1(Glutamate Receptor Delta-1 Subunit), which was previously reported to be associated with several psychiatric disorders and brain related traits, is particularly interesting. Variants with functional significance in this gene were identified from two cousins in our bipolar disorder pedigree. Our findings suggest a potential role for these genes and the related rare variants in the onset and development of bipolar disorder in this one family. Additional research is needed to replicate these findings and evaluate their patho-biological significance. Copyright © 2017 Elsevier B.V. All rights reserved.

  17. Development Potential, in a Greenhouse, of Cuttings of the Hybrid Eucalyptus grandis x Eucalyptus camaldulensis

    Directory of Open Access Journals (Sweden)

    M. N. Garcia

    2013-03-01

    Full Text Available Abstract: This study evaluated the potential for development in the greenhouse, cuttings of the hybrid of Eucalyptus grandis x Eucalyptus camaldulensis in Sinop - Mato Grosso and generated equations to estimate the percentage of rooting parameters. Were measured: the percentage of cuttings with some degree of modification, the percentage of cuttings in the percentage of cuttings with roots larger than 10 cm in length. Also measured was the neck diameter, height and leaf area index. The heights and leaf area showed lower development within the greenhouse. The rooting potential is based on curve speed of rooting and was found 12 days after staking. The identification of the optimal point of withdrawal of the shoots of the greenhouse through the intercept curves daily current increase curve (DCI e daily average increase (DAI, being 19 days after staking. The company derives the stakes with 24 days underdoing the potential of the species and structures used.Keywords: Eucalyptus, greenhouse management and rooting

  18. Assessment of the Joint Development Potential of Wave and Wind Energy in the South China Sea

    Directory of Open Access Journals (Sweden)

    Yong Wan

    2018-02-01

    Full Text Available The South China Sea is a major shipping hub between the West Pacific and Indian Oceans. In this region, the demand for energy is enormous, both for residents’ daily lives and for economic development. Wave energy and wind energy are two major clean and low-cost ocean sources of renewable energy. The reasonable development and utilization of these energy sources can provide a stable energy supply for coastal cities and remote islands of China. Before wave energy and wind energy development, however, we must assess the potential of each of these sources. Based on high-resolution and high-accuracy wave field data and wind field data obtained by ERA-Interim reanalysis for the recent 38-year period from 1979–2016, the joint development potential of wave energy and wind energy was assessed in detail for offshore and nearshore areas in the South China Sea. Based on potential installed capacity, the results revealed three promising areas for the joint development of nearshore wave energy and wind energy, including the Taiwan Strait, Luzon Strait and the sea southeast of the Indo-China Peninsula. For these three dominant areas (key stations, the directionality of wave energy and wind energy propagation were good in various seasons; the dominant wave conditions and the dominant wind conditions were the same, which is advantageous for the joint development of wave and wind energy. Existing well-known wave energy converters (WECs are not suitable for wave energy development in the areas of interest. Therefore, we must consider the distributions of wave conditions and develop more suitable WECs for these areas. The economic and environmental benefits of the joint development of wave and wind energy are high in these promising areas. The results described in this paper can provide references for the joint development of wave and wind energy in the South China Sea.

  19. Potential applications of the Internet of Things in sustainable rural development in South Africa

    CSIR Research Space (South Africa)

    Dlodlo, N

    2012-05-01

    Full Text Available Conference of Information Science and Computer Applications (ICISCA), Bali, Indonesia, 19-20 November 2012 Potential applications of the Internet of Things in sustainable rural development in South Africa Nomusa Dlodlo and Mofolo Mofolo CSIR...

  20. Energy Savings Potential and Research, Development, & Demonstration Opportunities for Residential Building Heating, Ventilation, and Air Conditioning Systems

    Energy Technology Data Exchange (ETDEWEB)

    Goetzler, William [Navigant Consulting, Inc., Burlington, MA (United States); Zogg, Robert [Navigant Consulting, Inc., Burlington, MA (United States); Young, Jim [Navigant Consulting, Inc., Burlington, MA (United States); Schmidt, Justin [Navigant Consulting, Inc., Burlington, MA (United States)

    2012-10-01

    This report is an assessment of 135 different heating, ventilation, and air-conditioning (HVAC) technologies for U.S. residential buildings to identify and provide analysis on 19 priority technology options in various stages of development. The analyses include an estimation of technical energy-savings potential, descriptions of technical maturity, descriptions of non-energy benefits, descriptions of current barriers for market adoption, and descriptions of the technology's applicability to different building or HVAC equipment types. From these technology descriptions, are suggestions for potential research, development and demonstration (RD&D) initiatives that would support further development of the priority technology options.

  1. Energy Savings Potential and Research, Development, & Demonstration Opportunities for Commercial Building Heating, Ventilation, and Air Conditioning Systems

    Energy Technology Data Exchange (ETDEWEB)

    none,

    2011-09-01

    This report covers an assessment of 182 different heating, ventilation, and air-conditioning (HVAC) technologies for U.S. commercial buildings to identify and provide analysis on 17 priority technology options in various stages of development. The analyses include an estimation of technical energy-savings potential, description of technical maturity, description of non-energy benefits, description of current barriers for market adoption, and description of the technology’s applicability to different building or HVAC equipment types. From these technology descriptions, are suggestions for potential research, development and demonstration (RD&D) initiatives that would support further development of the priority technology options.

  2. A decision tree approach to screen drinking water contaminants for multiroute exposure potential in developing guideline values.

    Science.gov (United States)

    Krishnan, Kannan; Carrier, Richard

    2017-07-03

    The consideration of inhalation and dermal routes of exposures in developing guideline values for drinking water contaminants is important. However, there is no guidance for determining the eligibility of a drinking water contaminant for its multiroute exposure potential. The objective of the present study was to develop a 4-step framework to screen chemicals for their dermal and inhalation exposure potential in the process of developing guideline values. The proposed framework emphasizes the importance of considering basic physicochemical properties prior to detailed assessment of dermal and inhalation routes of exposure to drinking water contaminants in setting guideline values.

  3. Typhi–Induced Septic Shock and Acute Respiratory Distress Syndrome in a Previously Healthy Teenage Patient Treated With High-Dose Dexamethasone

    Directory of Open Access Journals (Sweden)

    Melissa Brosset Ugas MD

    2016-05-01

    Full Text Available Typhoid fever is commonly characterized by fever and abdominal pain. Rare complications include intestinal hemorrhage, bowel perforation, delirium, obtundation, and septic shock. Herein we describe the case of a previously healthy 16-year-old male without history of travel, diagnosed with typhoid fever complicated by septic shock and acute respiratory distress syndrome treated with high-dose dexamethasone. This case details severe complications of typhoid fever that are uncommonly seen in developed countries, and the successful response to high-dose dexamethasone as adjunct therapy. High-dose dexamethasone treatment has reportedly decreased Salmonella Typhi mortality, but controlled studies specifically performed in children are lacking, and most reports of its use are over 30 years old and all have originated in developing countries. Providers should include Salmonella Typhi in the differential diagnosis of the pediatric patient with fever, severe abdominal pain, and enteritis, and be aware of its potentially severe complications and the limited data on safety and efficacy of adjunctive therapies that can be considered in addition to antibiotics.

  4. Biometrics — Developments and Potential

    NARCIS (Netherlands)

    Meuwly, Didier; Veldhuis, Raymond N.J.

    2014-01-01

    This article describes the use of biometric technology in forensic science, for the development of new methods and tools, improving the current forensic biometric applications, and allowing for the creation of new ones. The article begins with a definition and a summary of the development of this

  5. Strategies to avoid the loss of developmental potential in more than 200 million children in the developing world.

    Science.gov (United States)

    Engle, Patrice L; Black, Maureen M; Behrman, Jere R; Cabral de Mello, Meena; Gertler, Paul J; Kapiriri, Lydia; Martorell, Reynaldo; Young, Mary Eming

    2007-01-20

    This paper is the third in the Child Development Series. The first paper showed that more than 200 million children under 5 years of age in developing countries do not reach their developmental potential. The second paper identified four well-documented risks: stunting, iodine deficiency, iron deficiency anaemia, and inadequate cognitive stimulation, plus four potential risks based on epidemiological evidence: maternal depression, violence exposure, environmental contamination, and malaria. This paper assesses strategies to promote child development and to prevent or ameliorate the loss of developmental potential. The most effective early child development programmes provide direct learning experiences to children and families, are targeted toward younger and disadvantaged children, are of longer duration, high quality, and high intensity, and are integrated with family support, health, nutrition, or educational systems and services. Despite convincing evidence, programme coverage is low. To achieve the Millennium Development Goals of reducing poverty and ensuring primary school completion for both girls and boys, governments and civil society should consider expanding high quality, cost-effective early child development programmes.

  6. Is Uric Acid a Missing Link between Previous Gestational Diabetes Mellitus and the Development of Type 2 Diabetes at a Later Time of Life?

    Science.gov (United States)

    Molęda, Piotr; Fronczyk, Aneta; Safranow, Krzysztof; Majkowska, Lilianna

    2016-01-01

    A high level of uric acid (UA) is a strong, independent risk factor for type 2 diabetes mellitus. The relationship between UA levels and the development of type 2 diabetes in women with previous gestational diabetes mellitus (pGDM) remains unclear. The aim of study was to evaluate the UA levels in pGDM women in relation to their current nutritional status and carbohydrate metabolism. 199 women with pGDM diagnoses based on oral glucose tolerance tests (OGTTs) 5-12 years previously and a control group of 50 women without pGDM. The assessment included anthropometric parameters, body composition (Tanita SC-330S), current OGTT, insulin resistance index (HOMA-IR), β-cell function (HOMA-%B), HbA1c, lipids, and uric acid. No differences between groups were found in terms of age, time from the index pregnancy, anthropometric parameters, lipids or creatinine levels. The incidences of overweight and obesity were similar. Carbohydrate abnormalities were more frequent in the pGDM group than the control group (43.2% vs 12.0% p1). The women with pGDM had significantly higher fasting glucose, HbA1c, glucose and insulin levels in the OGTTs, but similar HOMA-IR values. Their UA levels were significantly higher (258±58 vs 230±50 μmol/L, p1, p1), creatinine level (β = 0.23, 95% CI 0.11-0.35, pdiabetes (β = 0.13, 95% CI 0.01-0.25, pdiabetes) was statistically significant (odds ratio 3.62 [95% CI 1.8-7.3], p1). Higher UA levels may be associated with the development of type 2 diabetes in pGDM women, also in these with normal body weights.

  7. Impact of the Z potential technique on reducing the sperm DNA fragmentation index, fertilization rate and embryo development.

    Science.gov (United States)

    Duarte, Carlos; Núñez, Víctor; Wong, Yat; Vivar, Carlos; Benites, Elder; Rodriguez, Urso; Vergara, Carlos; Ponce, Jorge

    2017-12-01

    In assisted reproduction procedures, we need to develop and enhance new protocols to optimize sperm selection. The aim of this study is to evaluate the ability of the Z potential technique to select sperm with intact DNA in non-normospermic patients and evaluate the impact of this selection on embryonic development. We analyzed a total of 174 human seminal samples with at least one altered parameter. We measured basal, post density gradients, and post density gradients + Z potential DNA fragmentation index. To evaluate the impact of this technique on embryo development, 54 cases were selected. The embryo development parameters evaluated were fertilization rate, cleavage rate, top quality embryos at the third day and blastocysts rate. We found significant differences in the study groups when we compared the sperm fragmentation index by adding the Z potential technique to density gradient selection vs. density gradients alone. Furthermore, there was no significant difference in the embryo development parameters between the low sperm fragmentation index group vs. the moderate and high sperm fragmentation index groups, when selecting sperms with this new technique. The Z potential technique is a very useful tool for sperm selection; it significantly reduces the DNA fragmentation index and improves the parameters of embryo development. This technique could be considered routine for its simplicity and low cost.

  8. Trends and Future Potential of Payment for Ecosystem Services to Alleviate Rural Poverty in Developing Countries

    Directory of Open Access Journals (Sweden)

    Jeffrey C. Milder

    2010-06-01

    Full Text Available Payment for ecosystem services (PES is a market-based approach to environmental management that compensates land stewards for ecosystem conservation and restoration. Because low-income households and communities control much of the ecologically sensitive land in developing countries, they potentially stand to gain from PES, as environmentally responsible stewardship is assigned a value by various actors in society. To date, however, instances of PES benefiting the poor have been limited mainly to specific localities, small-scale projects, and a handful of broader government programs. We analyze the size, characteristics, and trends of PES to evaluate its future potential to benefit low-income land stewards in developing countries. We estimate that by the year 2030, markets for biodiversity conservation could benefit 10-15 million low-income households in developing countries, carbon markets could benefit 25-50 million, markets for watershed protection could benefit 80-100 million, and markets for landscape beauty and recreation could benefit 5-8 million. If payments and markets reach these potentials, they could provide a non-negligible contribution to poverty alleviation at the global level.

  9. The activity of spontaneous action potentials in developing hair cells is regulated by Ca(2+-dependence of a transient K+ current.

    Directory of Open Access Journals (Sweden)

    Snezana Levic

    Full Text Available Spontaneous action potentials have been described in developing sensory systems. These rhythmic activities may have instructional roles for the functional development of synaptic connections. The importance of spontaneous action potentials in the developing auditory system is underpinned by the stark correlation between the time of auditory system functional maturity, and the cessation of spontaneous action potentials. A prominent K(+ current that regulates patterning of action potentials is I(A. This current undergoes marked changes in expression during chicken hair cell development. Although the properties of I(A are not normally classified as Ca(2+-dependent, we demonstrate that throughout the development of chicken hair cells, I(A is greatly reduced by acute alterations of intracellular Ca(2+. As determinants of spike timing and firing frequency, intracellular Ca(2+ buffers shift the activation and inactivation properties of the current to more positive potentials. Our findings provide evidence to demonstrate that the kinetics and functional expression of I(A are tightly regulated by intracellular Ca(2+. Such feedback mechanism between the functional expression of I(A and intracellular Ca(2+ may shape the activity of spontaneous action potentials, thus potentially sculpting synaptic connections in an activity-dependent manner in the developing cochlea.

  10. Scoping study on SADC energy sector carbon market potential; SADC = Southern African Development Community

    Energy Technology Data Exchange (ETDEWEB)

    2010-10-22

    This study shows that, while there is a certain degree of institutional and project development capacity in the region and significant Clean Development Mechanism (CDM) potential, very little of this potential is currently being tapped. National institutional structures are mostly very new, understaffed, and working in isolation from each other. There are ongoing national CDM capacity building programmes in several SADC countries that will address barriers and develop projects at a national level, but there are also regional opportunities that these programmes will not address. For some of large scale project opportunities such as landfill gas, industrial energy use, fugitive emission and transport, a national approach is required because these projects depend on local industrial base, regulatory environment, and are also large enough that the carbon revenue can cover the transaction costs. There are a few key areas that should be addressed, however, at a regional level: Energy trade and power development: any low carbon power projects that are developed to serve regional energy needs and displace coal fired power can only receive carbon credits if the baseline is a regional power grid rather than just a national grid. This is also true for large scale energy efficiency projects in countries that have only hydropower - these would not receive any carbon credits unless there is justification for a regional grid definition that includes fossil fuel fired power stations.Small scale projects: While the total potential for small scale renewables may not be large in terms of tonnes of CO{sub 2} mitigated, the local development impacts of distributed renewable energy and energy efficiency projects are very large. For these projects to be implemented at a large enough scale to recoup the transaction costs of project development, a regional approach is critical. The CDM 'Programme of Activities' (PoA) approach is ideally suited for such regional small scale energy

  11. Marker-assisted selection as a potential tool for genetic improvement in developing countries: debating the issues

    International Nuclear Information System (INIS)

    Robinson, J.; Ruane, J.

    2007-01-01

    Marker-assisted selection (MAS) is a complementary technology, for use in conjunction with more established conventional methods of genetic selection, for plant and animal improvement. It has generated a good deal of expectations, many of which have yet to be realized. Although documentation is limited, the current impact of MAS on products delivered to farmers seems small. While the future possibilities and potential impacts of MAS are considerable, there are also obstacles to its use, particularly in developing countries. Principal among these are issues relating to current high costs of the technology and its appropriateness, given that publicly funded agricultural research in many developing countries is suboptimal and development priorities do not necessarily include genetic improvement programmes. Other potential obstacles to the uptake of MAS in developing countries include limited infrastructure, the absence of conventional selection and breeding programmes, poor private sector involvement and lack of research on specific crops of importance in developing countries. Intellectual property rights may also be an important constraint to development and uptake of MAS in the developing world. It is hoped that through partnerships between developing and developed country institutions and individuals, including public-private sector collaboration, MAS costs can be reduced, resources pooled and shared and capacity developed. With the assistance of the Consultative Group on International Agricultural Research (CGIAR) and international organizations such as FAO, developing countries can benefit more from MAS. These were some of the outcomes of a moderated e-mail conference, entitled 'Molecular Marker- Assisted Selection as a Potential Tool for Genetic Improvement of Crops, Forest Trees, Livestock and Fish in Developing Countries', that FAO hosted at the end of 2003. During the four-week conference, 627 people subscribed and 85 messages were posted, about 60 percent

  12. Uncovering product development competence by applying the laddering technique

    DEFF Research Database (Denmark)

    Jensen, Bjarne; Harmsen, Hanne

    This paper addresses companies' lack of implementation of success factors in new product development. Drawing on theories in the competence perspective and an exploratory empirical study, the paper points to two major areas that have not been covered by previous studies on new product development...... success factors. The two areas are individual employees' knowledge, skills, and values and norms. It is suggested that increased understanding of these two areas hold potential in making identified success factors more accessible to companies.......This paper addresses companies' lack of implementation of success factors in new product development. Drawing on theories in the competence perspective and an exploratory empirical study, the paper points to two major areas that have not been covered by previous studies on new product development...

  13. Previous geological exploration of antimony ore occurrences Krčeva Reka (eastern Serbia in terms of the potentiality of the epithermal gold

    Directory of Open Access Journals (Sweden)

    Vukas Radoslav B.

    2014-01-01

    Full Text Available This paper presents the results of a previous geological exploration of antimony ore occurrences in the area Krčeva river. Data analysis of geological, geophysical, geochemical prospecting and appropriate methods of laboratory testing identified a series of similarities to epithermal gold mineralization Carline type and formed a preliminary model of its creation.

  14. [Prevalence of previously diagnosed diabetes mellitus in Mexico.

    Science.gov (United States)

    Rojas-Martínez, Rosalba; Basto-Abreu, Ana; Aguilar-Salinas, Carlos A; Zárate-Rojas, Emiliano; Villalpando, Salvador; Barrientos-Gutiérrez, Tonatiuh

    2018-01-01

    To compare the prevalence of previously diagnosed diabetes in 2016 with previous national surveys and to describe treatment and its complications. Mexico's national surveys Ensa 2000, Ensanut 2006, 2012 and 2016 were used. For 2016, logistic regression models and measures of central tendency and dispersion were obtained. The prevalence of previously diagnosed diabetes in 2016 was 9.4%. The increase of 2.2% relative to 2012 was not significant and only observed in patients older than 60 years. While preventive measures have increased, the access to medical treatment and lifestyle has not changed. The treatment has been modified, with an increase in insulin and decrease in hypoglycaemic agents. Population aging, lack of screening actions and the increase in diabetes complications will lead to an increase on the burden of disease. Policy measures targeting primary and secondary prevention of diabetes are crucial.

  15. A four-body potential in multiquark states

    International Nuclear Information System (INIS)

    Warner, R.C.; Joshi, G.C.

    1980-01-01

    A detailed analysis is presented of the first member of a previously derived hierarchy of instanton generated many-body potentials for multiquark states. Comparison with two-body instanton generated potential in the heavy quark framework is made in the T-baryonium system

  16. Assessment of potential impacts of climate change on agricultural development in the Lower Benue River Basin.

    Science.gov (United States)

    Abah, Roland Clement; Petja, Brilliant Mareme

    2016-12-01

    Agriculture in the Lower Benue River Basin faces several challenges which threaten the future of agricultural development. This study was an assessment of potential impacts of climate change on agricultural development in the Lower Benue River Basin. Through analysis of physical and socioeconomic parameters, the study adapted an impact assessment model to rank potential impacts on agricultural development in the study area. Rainfall intensity seemed to be increasing with a gradual reduction in the number of rainy days. The average discharge at Makurdi hydrological station was 3468.24 cubic metres per second (m 3  s -1 ), and the highest peak flow discharge was 16,400 m 3  s -1 . The daily maximum temperature and annual temperature averages for the study area are gradually rising leading to increased heat stress. Physical and chemical analyses showed that the soils are moderately fertile but require effective application of inorganic and organic fertilisers. The main occupational activities in the study area are agricultural based. The identified potential impacts of climate change on agriculture were categorised under atmospheric carbon dioxides and oxides, rainfall intensity, frequency of floods and droughts, temperature intensity and variation, heat stress, surface water trends, and soil quality and fertility. The identified potential impacts related to population dynamics on agriculture were categorised under population growth, rural-urban migration, household income and infectious diseases and HIV and AIDS. Community-level mitigation strategies were proffered. Policy makers are advised to promote irrigation farming, support farmers with farm inputs and credit facilities and establish active agricultural extension services to support the sustainable development of agriculture.

  17. CONVERGENT (NBIC TECHNOLOGIES: PROBLEMS OF DEVELOPMENT AND TRANSFORMATIONAL POTENTIAL

    Directory of Open Access Journals (Sweden)

    И В Данилин

    2017-12-01

    Full Text Available Modern innovation policy is formed under strong influence of disruptive technologies con-cepts, which help mobilize support for Science and Technology (S&T policy, structure international S&T cooperation and system, etc. They are also important for the global processes, promising changes in leading powers cohort. This is why disruptive technology concepts are accented by the emerging economics, especially by BRIC nations. A concept of converging (or nano-bio-info-cognitive, also known as NBIC technologies is very illustrative. Being originally a part of the USA nanotechnology policy and transhumanistic discourse, it gradually evolved globally with focus on “Grand Challenges”. But, despite successes of technology convergence since 2000s, concept itself proved to be not fully operational, being mostly a metaphor for rising interdisciplinarity and discipline convergence. Nonetheless its revolutionary potential was meaningful, but linked not to technological, but institu-tional and socio-cultural dimensions. Among them were human capital development, changing logic of S&T organization, reforming S&T policies, formation of new culture and ethics of research and development, systemic development of national innovation systems. These ideas, implicitly present in the NBIC concept, were of a special importance for the emerging economies as key factors for their enforced growth and rising quality of development processes. But these issues were surprisingly weak articulated in NBIC concept. Partly that was the influence of transhumanist discourse with its escape from solving societal challenges by technological change of human self. Not less important was that NBIC were seen by elites as a mean to bypass deep reforms and buildup of innovation institutions. I.e., concepts of disruptive technologies represent a psychological sub-stitute for a really intense development. Uniqueness of NBIC is that it makes this contradiction very visible. As shown in

  18. Maximising the local development potential of Nature Tourism accommodation establishments in South Africa

    Directory of Open Access Journals (Sweden)

    Jayne M Rogerson

    2014-01-01

    Full Text Available Within extant scholarship on tourism and local development one knowledge gap concerns the role of the accommodation sector as a base for tourism-led local development in rural areas and small towns. The focus is upon nature tourism accommodation establishments which cluster mainly in geographically marginal areas in South Africa where poverty levels are high and the imperative exists for new drivers of economic and social development. A national audit of nature tourism accommodation establishments confirms their potential critical relevance for local development planning in many parts of the country. Nevertheless, existing evidence points to limitations in local linkages through the food supply chain. A critical review is given of several constraints which impact upon tourism-agriculture linkages with policy conclusions for strengthening such linkages.

  19. Sublimator Driven Coldplate Engineering Development Unit Test Results and Development of Second Generation SDC

    Science.gov (United States)

    Stephan, Ryan A.; Sheth, Rubik B.

    2009-01-01

    The Sublimator Driven Coldplate (SDC) is a unique piece of thermal control hardware that has several advantages over a traditional thermal control scheme. The principal advantage is the possible elimination of a pumped fluid loop, potentially increasing reliability and reducing complexity while saving both mass and power. Furthermore, the Integrated Sublimator Driven Coldplate (ISDC) concept couples a coolant loop with the previously described SDC hardware. This combination allows the SDC to be used as a traditional coldplate during long mission phases. The previously developed SDC technology cannot be used for long mission phases due to the fact that it requires a consumable feedwater for heat rejection. Adding a coolant loop also provides for dissimilar redundancy on the Altair Lander ascent module thermal control system, which is the target application for this technology. Tests were performed on an Engineering Development Unit at NASA s Johnson Space Center to quantify and assess the performance of the SDC. Correlated thermal math models were developed to help explain the test data. The paper also outlines the preliminary results of an ISDC concept being developed.

  20. Potential of Compost with Some Added Supplementary Materials on the Development of Agaricus blazei Murill

    OpenAIRE

    Horm, Visal; Ohga, Shoji; 大賀, 祥治

    2008-01-01

    Potential of compost on the development of Agaricus blazei Murill was evaluated on various compost concentrations with two kinds of supplementary materials. Sugarcane compost as well as cattle compost added with sawdust and rice bran was influential substrates on mycelial growth and fruit body development. The fast spawn running was realized on cattle compost concentrations, but primordial formation and fruit body development took a short period on sugarcane compost concentrations. All cattle...

  1. The Impact of a Potential Shale Gas Development in Germany and the United Kingdom on Local and Regional Air Quality

    Science.gov (United States)

    Weger, L.; Lupascu, A.; Cremonese, L.; Butler, T. M.

    2017-12-01

    Numerous countries in Europe that possess domestic shale gas reserves are considering exploiting this unconventional gas resource as part of their energy transition agenda. While natural gas generates less CO2 emissions upon combustion compared to coal or oil, making it attractive as a bridge in the transition from fossil fuels to renewables, production of shale gas leads to emissions of CH4 and air pollutants such as NOx, VOCs and PM. These gases in turn influence the climate as well as air quality. In this study, we investigate the impact of a potential shale gas development in Germany and the United Kingdom on local and regional air quality. This work builds on our previous study in which we constructed emissions scenarios based on shale gas utilization in these counties. In order to explore the influence of shale gas production on air quality, we investigate emissions predicted from our shale gas scenarios with the Weather Research and Forecasting model with chemistry (WRF-Chem) model. In order to do this, we first design a model set-up over Europe and evaluate its performance for the meteorological and chemical parameters. Subsequently we add shale gas emissions fluxes based on the scenarios over the area of the grid in which the shale gas activities are predicted to occur. Finally, we model these emissions and analyze the impact on air quality on both a local and regional scale. The aims of this work are to predict the range of adverse effects on air quality, highlight the importance of emissions control strategies in reducing air pollution, to promote further discussion, and to provide policy makers with information for decision making on a potential shale gas development in the two study countries.

  2. Potential for offshore geothermal developments using deep gas wells

    Energy Technology Data Exchange (ETDEWEB)

    Teodoriu, C.; Falcone, G. [Technische Univ. Clausthal, Clausthal-Zellerfeld (Germany). ITE

    2013-08-01

    The development of geothermal resources is steadily increasing as operators meet the challenge of maximising the temperature difference between production and injection wells, while minimising the wellhead temperature of the latter. At present, the minimum working wellhead temperature reported for the heat-to-electricity conversion cycles is limited to about 80 C. The cycle efficiency can be improved by reducing the injection temperature, which is the temperature at which the fluid exits the process. This paper evaluates the potential for generating electricity with a subsea geothermal plant using the difference between downhole reservoir temperature and that of the cold seawater at the mud line. The temperature in the world's oceans is relatively constant, ranging from 0 to 4 C at around 400 meters water depth. The use of these lower offshore water temperatures may help boost geothermal energy development. Deep gas resources are considered to be held within reservoirs below 4600 meters (15000 feet) and are relatively undeveloped as the risks and costs involved in drilling and producing such resources are extremely high. These deep resources have high reservoir temperatures, which offer an opportunity for geothermal exploitation if a new development concept can be formulated. In particular, the well design and reservoir development plan should consider reutilising existing well stock, including dry and plugged and abandoned wells for geothermal application once the gas field has been depleted. The major risks considered in this study include alternative uses of wells in no flow or rapid depletion situations. Reutilisation of the wells of depleted gas reservoirs will invariably lead to lower geothermal development costs compared with starting a geothermal campaign by drilling new wells. In particular, the well design and reservoir development plan should consider reutilising existing well stock, including dry and plugged and abandoned wells for geothermal

  3. Interdisciplinary researches for potential developments of drugs and natural products

    Directory of Open Access Journals (Sweden)

    Arunrat Chaveerach

    2017-04-01

    Full Text Available Developments of drugs or natural products from plants are possibly made, simple to use and lower cost than modern drugs. The development processes can be started with studying local wisdom and literature reviews to choose the plants which have long been used in diverse areas, such as foods, traditional medicine, fragrances and seasonings. Then those data will be associated with scientific researches, namely plant collection and identification, phytochemical screening by gas chromatography-mass spectrometry, pharmacological study/review for their functions, and finally safety and efficiency tests in human. For safety testing, in vitro cell toxicity by cell viability assessment and in vitro testing of DNA breaks by the comet assay in human peripheral blood mononuclear cells can be performed. When active chemicals and functions containing plants were chosen with safety and efficacy for human uses, then, the potential medicinal natural products will be produced. Based on these procedures, the producing cost will be cheaper and the products can be evaluated for their clinical properties. Thus, the best and lowest-priced medicines and natural products can be distributed worldwide.

  4. Interdisciplinary researches for potential developments of drugs and natural products

    Institute of Scientific and Technical Information of China (English)

    Arunrat Chaveerach; Runglawan Sudmoon; Tawatchai Tanee

    2017-01-01

    Developments of drugs or natural products from plants are possibly made,simple to use and lower cost than modern drugs.The development processes can be started with studying local wisdom and literature reviews to choose the plants which have long been used in diverse areas,such as foods,traditional medicine,fragrances and seasonings.Then those data will be associated with scientific researches,namely plant collection and identification,phytochemical screening by gas chromatography-mass spectrometry,pharmacological study/review for their functions,and finally safety and efficiency tests in human.For safety testing,in vitro cell toxicity by cell viability assessment and in vitro testing of DNA breaks by the comet assay in human peripheral blood mononuclear cells can be performed.When active chemicals and functions containing plants were chosen with safety and efficacy for human uses,then,the potential medicinal natural products will be produced.Based on these procedures,the producing cost will be cheaper and the products can be evaluated for their clinical properties.Thus,the best and lowest-priced medicines and natural products can be distributed worldwide.

  5. Using GeoRePORT to report socio-economic potential for geothermal development

    Energy Technology Data Exchange (ETDEWEB)

    Young, Katherine R.; Levine, Aaron

    2018-07-01

    The Geothermal Resource Portfolio Optimization and Reporting Tool (GeoRePORT, http://en.openei.org/wiki/GeoRePORT) was developed for reporting resource grades and project readiness levels, providing the U.S. Department of Energy a consistent and comprehensible means of evaluating projects. The tool helps funding organizations (1) quantitatively identify barriers, (2) develop measureable goals, (3) objectively evaluate proposals, including contribution to goals, (4) monitor progress, and (5) report portfolio performance. GeoRePORT assesses three categories: geological, technical, and socio-economic. Here, we describe GeoRePORT, then focus on the socio-economic assessment and its applications for assessing deployment potential in the U.S. Socio-economic attributes include land access, permitting, transmission, and market.

  6. Verification of the SLC wake potentials

    International Nuclear Information System (INIS)

    Bane, K.; Weiland, T.

    1983-01-01

    The accurate knowledge of the monopole, dipole, and quadrupole wake potentials is essential for SLC. These wake potentials were previously computed by the modal method. The time domain code TBCI allows independent verification of these results. This comparison shows that the two methods agree to within 10% for bunch lengths down to 1 mm. TBCI results also indicate that rounding the irises gives at least a 10% reduction in the wake potentials

  7. Spectrophotometric determination of uranium by previous extraction chromatography separation in polimetalic mineral, phosphorites and technological licours

    International Nuclear Information System (INIS)

    Moreno Bermudez, J.; Cabrera Quevedo, C.; Alfonso Mendez, L.; Rodriguez Aguilera, M.

    1994-01-01

    The development of an analytical procedure for spectrophotometric determination of uranium in polimetalic mineral, phosphorites and technological licours is described. The method is based on the previous separation of interfering elements by extraction chromatography and on spectrophotometric determination of uranium (IV) with arsenazo III in concentrated hydrochloric acid. Tributyl phosphate impregnate on politetrafluoroethylene is used as stationary phase and 5.5 M nitric acid is used as movie phase. The influence of matrix-component elements was studies. The development procedure was applied to real samples, being the results compared with those obtained by other well established analytical methods like gamma-spectrometry, laser fluorimetric, spectrophotometry previous uranium separation by liquid liquid extraction and anion exchange. The reproducibility is evaluated and the detection limited has been established for each studied matrix. A procedure for correcting the thorium interference has been developed for samples with a Th/ 3U8O higher than 0.2

  8. T-type calcium channel antagonism decreases motivation for nicotine and blocks nicotine- and cue-induced reinstatement for a response previously reinforced with nicotine.

    Science.gov (United States)

    Uslaner, Jason M; Vardigan, Joshua D; Drott, Jason M; Uebele, Victor N; Renger, John J; Lee, Ariel; Li, Zhaoxia; Lê, A D; Hutson, Pete H

    2010-10-15

    Recent evidence suggests an involvement of T-type calcium channels in the effects of drugs of abuse. We examined the influence of the novel, potent, and selective T-type calcium channel antagonist [2-(4-cyclopropylphenyl)-N-((1R)-1-{5-[2,2,2-trifluoroethyl]oxo}pyridine-2-yl)ethyl]acetamide] (TTA-A2) (.3, 1, or 3 mg/kg) on motivation for nicotine, as measured by nicotine self-administration on a progressive ratio (PR) schedule, and nicotine- and cue-induced reinstatement for a response previously reinforced with nicotine delivery (n = 11 or 12 Long Evans rats/group). Furthermore, we examined the specificity of the TTA-A2 effects by characterizing its influence on PR responding for food (in the absence or presence of nicotine-potentiated responding), food- versus nicotine-induced cue-potentiated reinstatement for a response previously reinforced by food administration (n = 11 or 12 Wistar Hannover rats/group), and its ability to induce a conditioned place aversion. TTA-A2 dose-dependently decreased self-administration of nicotine on a PR schedule and the ability of both nicotine and a cue paired with nicotine to reinstate responding. The effects were specific for nicotine's incentive motivational properties, as TTA-A2 did not influence responding for food on a PR schedule but did attenuate the ability of nicotine to potentiate responding for food. Likewise, TTA-A2 did not alter food-induced cue-potentiated reinstatement for a response previously reinforced by food but did decrease nicotine-induced cue-potentiated reinstatement. Finally, TTA-A2 did not produce an aversive state, as indicated by a lack of ability to induce conditioned place aversion. These data suggest that T-type calcium channel antagonists have potential for alleviating nicotine addiction by selectively decreasing the incentive motivational properties of nicotine. Copyright © 2010 Society of Biological Psychiatry. Published by Elsevier Inc. All rights reserved.

  9. Assessing values of Arctic wildlife and habitat subject to potential petroleum development

    Energy Technology Data Exchange (ETDEWEB)

    McCabe, Thomas R. (USFWS, Alaska Fish and Wildlife Research Center, Fairbanks, AK (United States))

    1994-02-01

    The National Wildlife Refuge system of the US Fish and Wildlife Service (FWS) is predicated on the principle of conserving and perpetuating the natural diversity and abundance of wildlife and wildlands. The prospect of petroleum development on the 1002 area of the 10,000 km[sup 2] pristine coastal plain of the Arctic National Wildlife Refuge (ANWR) has been a contentious national issue. The FWS assessed the habitat and its constituent wildlife species to determine potential impacts from this development. As part of the assessment effort, research was conducted on the 163,000 member porcupine caribou (Rangifer tarandus) herd, its primary predator at calving, brown bear (Ursus arctos), and the vegetation communities on the coastal plain. We found the traditional calving area within the 1002 area had significantly greater forage species availability and nutrient quality than areas peripheral to the 1002 area. Increased post-perinatal, predator-related mortality has been associated with the foothills and mountains adjacent to the 1002 area. Displacement of the calving caribou from the 1002 area would mean a lesser abundance of high quality forage for calving cows, and calves would be subjected to a potentially higher predation risk. These factors could have a negative impact on the population dynamics of the Porcupine herd. If petroleum development were authorized on the 1002 area of ANWR, the challenge for the FWS will be to assure that the dynamics of the tundra ecosystem are adequately understood and to conserve the abundance and diversity of natural wildlife populations and their habitat

  10. Assessing values of Arctic wildlife and habitat subject to potential petroleum development

    International Nuclear Information System (INIS)

    McCabe, Thomas R.

    1994-01-01

    The National Wildlife Refuge system of the US Fish and Wildlife Service (FWS) is predicated on the principle of conserving and perpetuating the natural diversity and abundance of wildlife and wildlands. The prospect of petroleum development on the 1002 area of the 10,000 km 2 pristine coastal plain of the Arctic National Wildlife Refuge (ANWR) has been a contentious national issue. The FWS assessed the habitat and its constituent wildlife species to determine potential impacts from this development. As part of the assessment effort, research was conducted on the 163,000 member porcupine caribou (Rangifer tarandus) herd, its primary predator at calving, brown bear (Ursus arctos), and the vegetation communities on the coastal plain. We found the traditional calving area within the 1002 area had significantly greater forage species availability and nutrient quality than areas peripheral to the 1002 area. Increased post-perinatal, predator-related mortality has been associated with the foothills and mountains adjacent to the 1002 area. Displacement of the calving caribou from the 1002 area would mean a lesser abundance of high quality forage for calving cows, and calves would be subjected to a potentially higher predation risk. These factors could have a negative impact on the population dynamics of the Porcupine herd. If petroleum development were authorized on the 1002 area of ANWR, the challenge for the FWS will be to assure that the dynamics of the tundra ecosystem are adequately understood and to conserve the abundance and diversity of natural wildlife populations and their habitat

  11. The effect of a glucagon-like peptide-1 receptor agonist on glucose tolerance in women with previous gestational diabetes mellitus

    DEFF Research Database (Denmark)

    Foghsgaard, Signe; Vedtofte, Louise; Mathiesen, Elisabeth R

    2013-01-01

    INTRODUCTION: Pregnancy is associated with decreased insulin sensitivity, which is usually overcome by a compensatory increase in insulin secretion. Some pregnant women are not able to increase their insulin secretion sufficiently, and consequently develop gestational diabetes mellitus (GDM......). The disease normally disappears after delivery. Nevertheless, women with previous GDM have a high risk of developing type 2 diabetes (T2D) later in life. We aim to investigate the early development of T2D in women with previous GDM and to evaluate whether treatment with the glucagon-like peptide-1 receptor...

  12. Intermediate Latency-Evoked Potentials of Multimodal Cortical Vestibular Areas: Galvanic Stimulation

    Directory of Open Access Journals (Sweden)

    Stefan Kammermeier

    2017-11-01

    Full Text Available IntroductionHuman multimodal vestibular cortical regions are bilaterally anterior insulae and posterior opercula, where characteristic vestibular-related cortical potentials were previously reported under acoustic otolith stimulation. Galvanic vestibular stimulation likely influences semicircular canals preferentially. Galvanic stimulation was compared to previously established data under acoustic stimulation.Methods14 healthy right-handed subjects, who were also included in the previous acoustic potential study, showed normal acoustic and galvanic vestibular-evoked myogenic potentials. They received 2,000 galvanic binaural bipolar stimuli for each side during EEG recording.ResultsVestibular cortical potentials were found in all 14 subjects and in the pooled data of all subjects (“grand average” bilaterally. Anterior insula and posterior operculum were activated exclusively under galvanic stimulation at 25, 35, 50, and 80 ms; frontal regions at 30 and 45 ms. Potentials at 70 ms in frontal regions and at 110 ms at all of the involved regions could also be recorded; these events were also found using acoustic stimulation in our previous study.ConclusionGalvanic semicircular canal stimulation evokes specific potentials in addition to those also found with acoustic otolith stimulation in identically located regions of the vestibular cortex. Vestibular cortical regions activate differently by galvanic and acoustic input at the peripheral sensory level.SignificanceDifferential effects in vestibular cortical-evoked potentials may see clinical use in specific vertigo disorders.

  13. DEVELOPMENT OF INNOVATIVE LEADERSHIP POTENTIAL IN EDUCATION SYSTEM

    Directory of Open Access Journals (Sweden)

    A. Y. Ogorodnikov

    2014-01-01

    Full Text Available The aim of the research is to reveal the educational formation mechanisms of manager personality, including the ability to operate the intellectual capital at all levels of activities, to disclose innovative competence in dealingwith special problems as the regulation of social and organizational processes, to apply knowledge on the management factors efficiency, human needs, attitudes, and modern management techniques. Methods. The research outcomes include the methods of social control organization in the innovation sphere, based on the design of the value system that integrates the intellectual activities of employees into a unified semantic informational space, which promotes the socio-cultural development of various social groups and institutions. Sociological methods of the expert survey in the form of in-depth interviews are applied as an empirical basis of the present study. Cognitive modeling method is used in the course of interpretation and data analysis. The author draws the conclusion using the method of dialectical opposition unity. Results. The research findings demonstrate the characteristics of managers who are good at effective mobilizing the intellectual resources while encouraging the staff members’ capabilities of self-development and self-training. The article deals with the integral indicators of management entity engagement including the arrangement of conditions and interaction system that sustain innovative values updating in some organizations in order to improve organization efficiency in accordance with the stated objectives.Scientific novelty. The author summarizes the theoretical basis of modern means and methods of social institutions management, including educational institutions. General management mechanisms of innovative leadership potential realization are presented in the form of the hierarchic unity. It is shown that intellectualcapital integration into innovative processes of an organization

  14. Development of a high-throughput method for the systematic identification of human proteins nuclear translocation potential

    Directory of Open Access Journals (Sweden)

    Kawai Jun

    2009-09-01

    Full Text Available Abstract Background Important clues to the function of novel and uncharacterized proteins can be obtained by identifying their ability to translocate in the nucleus. In addition, a comprehensive definition of the nuclear proteome undoubtedly represents a key step toward a better understanding of the biology of this organelle. Although several high-throughput experimental methods have been developed to explore the sub-cellular localization of proteins, these methods tend to focus on the predominant localizations of gene products and may fail to provide a complete catalog of proteins that are able to transiently locate into the nucleus. Results We have developed a method for examining the nuclear localization potential of human gene products at the proteome scale by adapting a mammalian two-hybrid system we have previously developed. Our system is composed of three constructs co-transfected into a mammalian cell line. First, it contains a PCR construct encoding a fusion protein composed of a tested protein, the PDZ-protein TIP-1, and the transactivation domain of TNNC2 (referred to as ACT construct. Second, our system contains a PCR construct encoding a fusion protein composed of the DNA binding domain of GAL4 and the PDZ binding domain of rhotekin (referred to as the BIND construct. Third, a GAL4-responsive luciferase reporter is used to detect the reconstitution of a transcriptionally active BIND-ACT complex through the interaction of TIP-1 and rhotekin, which indicates the ability of the tested protein to translocate into the nucleus. We validated our method in a small-scale feasibility study by comparing it to green fluorescent protein (GFP fusion-based sub-cellular localization assays, sequence-based computational prediction of protein sub-cellular localization, and current sub-cellular localization data available from the literature for 22 gene products. Conclusion Our reporter-based system can rapidly screen gene products for their ability

  15. 75 FR 76056 - FEDERAL REGISTER CITATION OF PREVIOUS ANNOUNCEMENT:

    Science.gov (United States)

    2010-12-07

    ... SECURITIES AND EXCHANGE COMMISSION Sunshine Act Meeting FEDERAL REGISTER CITATION OF PREVIOUS ANNOUNCEMENT: STATUS: Closed meeting. PLACE: 100 F Street, NE., Washington, DC. DATE AND TIME OF PREVIOUSLY ANNOUNCED MEETING: Thursday, December 9, 2010 at 2 p.m. CHANGE IN THE MEETING: Time change. The closed...

  16. The Effects of the Previous Outcome on Probabilistic Choice in Rats

    Science.gov (United States)

    Marshall, Andrew T.; Kirkpatrick, Kimberly

    2014-01-01

    This study examined the effects of previous outcomes on subsequent choices in a probabilistic-choice task. Twenty-four rats were trained to choose between a certain outcome (1 or 3 pellets) versus an uncertain outcome (3 or 9 pellets), delivered with a probability of .1, .33, .67, and .9 in different phases. Uncertain outcome choices increased with the probability of uncertain food. Additionally, uncertain choices increased with the probability of uncertain food following both certain-choice outcomes and unrewarded uncertain choices. However, following uncertain-choice food outcomes, there was a tendency to choose the uncertain outcome in all cases, indicating that the rats continued to “gamble” after successful uncertain choices, regardless of the overall probability or magnitude of food. A subsequent manipulation, in which the probability of uncertain food varied within each session as a function of the previous uncertain outcome, examined how the previous outcome and probability of uncertain food affected choice in a dynamic environment. Uncertain-choice behavior increased with the probability of uncertain food. The rats exhibited increased sensitivity to probability changes and a greater degree of win–stay/lose–shift behavior than in the static phase. Simulations of two sequential choice models were performed to explore the possible mechanisms of reward value computations. The simulation results supported an exponentially decaying value function that updated as a function of trial (rather than time). These results emphasize the importance of analyzing global and local factors in choice behavior and suggest avenues for the future development of sequential-choice models. PMID:23205915

  17. Implant breast reconstruction after salvage mastectomy in previously irradiated patients.

    Science.gov (United States)

    Persichetti, Paolo; Cagli, Barbara; Simone, Pierfranco; Cogliandro, Annalisa; Fortunato, Lucio; Altomare, Vittorio; Trodella, Lucio

    2009-04-01

    The most common surgical approach in case of local tumor recurrence after quadrantectomy and radiotherapy is salvage mastectomy. Breast reconstruction is the subsequent phase of the treatment and the plastic surgeon has to operate on previously irradiated and manipulated tissues. The medical literature highlights that breast reconstruction with tissue expanders is not a pursuable option, considering previous radiotherapy a contraindication. The purpose of this retrospective study is to evaluate the influence of previous radiotherapy on 2-stage breast reconstruction (tissue expander/implant). Only patients with analogous timing of radiation therapy and the same demolitive and reconstructive procedures were recruited. The results of this study prove that, after salvage mastectomy in previously irradiated patients, implant reconstruction is still possible. Further comparative studies are, of course, advisable to draw any conclusion on the possibility to perform implant reconstruction in previously irradiated patients.

  18. Potential role of power authorities in offshore wind power development in the US

    International Nuclear Information System (INIS)

    Dhanju, Amardeep; Firestone, Jeremy; Kempton, Willett

    2011-01-01

    This article examines how power authorities could facilitate and manage offshore wind power development in US coastal waters. The power authority structure is an American 20th century institution for managing energy resources-a form of a public authority or public corporation dedicated to creating, operating and maintaining electric generation and transmission infrastructure. Offshore wind power is characterized by high capital costs but no fuel costs and thus low operating costs. Therefore a power authority, by virtue of its access to low-cost capital and managerial flexibility, could facilitate offshore wind power development by reducing financial risk of developing and lowering debt payments, thus improving the risk profile and lowering the cost of electricity production. Additionally, power authorities can be made up of multiple states, thus opening the possibility for joint action by neighboring coastal states. Using primary and secondary data, we undertake an in-depth analysis of the potential benefits and shortcomings of a power authority approach. - Highlights: → Proposes an institutional solution in the form of power authority for offshore wind power. → Power authority structure can significantly lower the cost of capital. → Tax-free bond financing available to power authority can significantly reduce the cost of energy. → It can enhance regional collaboration among coastal states to harness the offshore wind potential.

  19. Development of unutilized biomass potentials in forestry and landscape conservation. Logistical challenges and potential uses of innovative telematics technologies and services

    Energy Technology Data Exchange (ETDEWEB)

    Erhardt, I; Waesche, M [Fraunhofer Institute for Factory Operation and Automation IFF, Magdeburg (Germany)

    2006-07-01

    Among other things, the heterogeneity of the types, quantities and numbers of potential sources and sinks as well as the means of transportation used continue to make it difficult to describe as a whole logistics processes for developing raw material in forest and field, especially for the wood processing industry, or for recovering renewable energies. Conventional methods of logistics controlling and measurement only capture these processes incompletely and partially. Innovative developments in the field of mobile information technologies are opening tremendous potentials for improving logistics processes. Taking into account the multitude of national and international standards and guidelines in this field, catchphrases such as location based services or LBS and radio frequency identification or RFID already stand for effective and practicable solutions in traditional fields of application for logistics. Building upon RFID and telematic trends and applications in classical fields of logistics, this paper presents current successes and addresses further needs in the forestry and wood processing industries as well as related sectors. The following theses are put forth for discussion: The use of RFID and telematics must guarantee a quantifiable benefit for everyone involved in a process. The development of a broader range of solutions customized for individual cases and preconfigured will help the technology to a breakthrough more than striving for the universal solution will. Standardization is a fundamental prerequisite to user acceptance in general and investment protection, particularly for smaller enterprises. (orig.)

  20. 28 CFR 10.5 - Incorporation of papers previously filed.

    Science.gov (United States)

    2010-07-01

    ... 28 Judicial Administration 1 2010-07-01 2010-07-01 false Incorporation of papers previously filed... CARRYING ON ACTIVITIES WITHIN THE UNITED STATES Registration Statement § 10.5 Incorporation of papers previously filed. Papers and documents already filed with the Attorney General pursuant to the said act and...

  1. Development of an investigation method for redox condition of rocks by self potential (SP) method

    International Nuclear Information System (INIS)

    Kubota, Kenji; Inohara, Yoshiki; Oyama, Takahiro

    2012-01-01

    One of the major issues in subsurface disposal of low level radioactive wastes is that long term behaviors of sedimentary rocks can be affected by geochemical factors. Redox conditions can affect to corrosion of metal included in artificial barrier or wastes and adsorption characteristics of a nuclide. Therefore, it is necessary to develop a method for evaluating the redox conditions around natural barrier at waste facilities. In general, geochemical properties are acquired by rock samples or water sampling at a borehole. However, there is a possibility not to acquire data we want to evaluate. If geophysical methods are applied, redox conditions can be evaluated widely and briefly. There is a possibility that self potential (SP) and redox conditions have a correlation. So we have conducted self potential method around test caverns where redox front can be observed at the Rokkasho site. The results demonstrated that self potential decreased around redox front. There was a positive correlation between self potential and pH. One of the factors of self potential change is difference of elevation, however, self potential change around redox front was larger than that expected from elevation difference. Zeta potential is one of the important factors for determination of self potential, and it had a correlation with self potential or pH. Therefore, there is a possibility that self potential change occurs by geochemical condition changes around redox front, and redox condition can be detected by self potential method. (author)

  2. A PET scanner developed by CERN

    CERN Multimedia

    Laurent Guiraud

    1998-01-01

    This image shows a Position Emission Tomography (PET) scanner at the Hopital Cantonal Universitaire de Genève. Development of the multiwire proportional chamber at CERN in the mid-1970s was soon seen as a potential device for medical imaging. It is much more sensitive than previous devices and greatly reduced the dose of radiation received by the patient.

  3. Potential impacts of biofuel development on food security in Botswana: A contribution to energy policy

    International Nuclear Information System (INIS)

    Kgathi, Donald L.; Mfundisi, K.B.; Mmopelwa, G.; Mosepele, K.

    2012-01-01

    Biofuel development continues to be a critical development strategy in Africa because it promises to be an important part of the emerging bio-economy. However, there is a growing concern that the pattern of biofuel development is not always consistent with the principles of sustainable development. This paper assesses the potential of the impacts of biofuel development on food security in Botswana. Drawing on informal and semi-structured interviews, the paper concludes that there is potential for the development of biofuels in Botswana without adverse effects on food security due mainly to availability of idle land which accounted for 72% of agricultural land in the eastern part of the country in 2008. It is suggested that farmers could be incentivized to produce energy crops and more food from such land. Although it is hypothesized that the implementation of biofuel development programmes in other countries had an impact on local commodity prices during the period 2005–2008 in Botswana, it is argued that local biofuel production may not necessarily lead to a substantial increase in commodity food prices because land availability is not a major issue. The paper makes policy recommendations for sustainable biofuel development in Botswana. - Highlights: ► Biofuel development in Botswana can be pursued without harming food security. ► There is plenty idle land which could be used for biofuel and food production. ► Biofuel production will not lead to significant increases in food prices. ► There is need to define land for biofuels to avoid future scarcity of land for food production.

  4. Differences between previously married and never married 'gay' men: family background, childhood experiences and current attitudes.

    Science.gov (United States)

    Higgins, Daryl J

    2004-01-01

    Despite a large body of literature on the development of sexual orientation, little is known about why some gay men have been (or remain) married to a woman. In the current study, a self-selected sample of 43 never married gay men ('never married') and 26 gay men who were married to a woman ('previously married') completed a self-report questionnaire. Hypotheses were based on five possible explanations for gay men's marriages: (a) differences in sexual orientation (i.e., bisexuality); (b) internalized homophobia; (c) religious intolerance; (d) confusion created because of childhood/adolescent sexual experiences; and/or (e) poor psychological adjustment. Previously married described their families' religious beliefs as more fundamentalist than never married. No differences were found between married' and never married' ratings of their sexual orientation and identity, and levels of homophobia and self-depreciation. Family adaptability and family cohesion and the degree to which respondents reported having experienced child maltreatment did not distinguish between previously married and never married. The results highlight how little is understood of the reasons why gay men marry, and the need to develop an adequate theoretical model.

  5. Influence of the Level of the Development of Skills on Labour Potential, its Implementation and Choice of Work Position

    Directory of Open Access Journals (Sweden)

    Kseniya Aleksandrovna Ustinova

    2016-09-01

    Full Text Available The article deals with the sociological assessment of the skills level and identification of its influence on some aspects of labour activity: the realization of labour potential, choice of the scope of activity, position and occupation. It suggests an approach based on the subjective evaluation of the population as an instrument of the skills level assessment. The received results are compared with the indirect estimates allowing to characterize some particular components of labour potential which are similar to the considered skills. A specific feature of the research is not only the determination of the professional sphere, occupation and position on the skills level, but also the accounting of the reverse effect. The methodological tools including the methods for the assessment of skills level, labour potential and extent of its implementation in a labour activity have been approved in the Vologda region. The study revealed that, at the present time, the most developed skills are the teamwork, communication and mutual understanding while the least developed ones are the initiative and creativity as well as ability to be retrained and readiness to increase the professional level. It shows that the employees of socially oriented spheres and also the representatives of state structures have more developed skills. At the same time, the development of innovative skills not only leads to the growth of labour potential, but also creates conditions for the employment in workplaces with higher skills requirements. The paper shows that higher skills level along with higher skills requirements leads to more complete implementation of cumulative potential in the labour activity. The received results can be used by regional authorities for the development of the analytical system of labour market, the development of labour force and the labour potential of the population.

  6. MAPPING OF POTENTIAL AGRICULTURE IN THE DEVELOPMENT OF PRIORITY AGROINDUSTRY IN KEPULAUAN MERANTY REGENCY

    Directory of Open Access Journals (Sweden)

    Septina Elida

    2017-06-01

    Full Text Available The agricultural sector has an important role for rural communities in moving its economy. Therefore, that agricultural potential should be utilized as much as possible for socialwelfare. This study aimed to analyze the potential of agricultural commodities and priority of the factors that determine superioragroindustrybased potensial of agricultural commodities. This study usedsurvey, which was conduct in the Meranti IslandsDistrict from January to May 2016.Respondents involving stakeholders from experts, government agencies and community leaders. The analysis was the Hirarchi Analytical Process (AHP. The results showedthat the potential of agricultural commodities which was develope in Meranti Islands District were sago, coconut and rubber. Determinants: 1 Natural resources (climate, rainfall and land suitability, the priority factor were the land suitability and climate. 2 Human resources (formal education and skills, the priority factor was skill, 3 capital (land, seeds, tools, technology, and ease of cultivation, the priority factor were land, seeds, ease of cultivation. 4 Socio-economic and cultural (ethnic, contribution to GDP, the priority factor was the contribution to the GDP.Superior agroindustriesthat has be developed in the District of Meranti Islands based agricultural potential was agroindustrial sago and coconut. Determinants: 1. The technical aspects (raw materials, capital, technology and infrastructure, the priority factor were the raw material and capital. 2 Economical aspects (price, market, downstream prospects, and the contribution to the GDP, the priority factor are market and downstream prospects. 3 Socio-economic and cultural aspects (education and labor absorption, the priority factor in Agroindustry sago was education, whereas in the palm agro-industry was labor absorption. 

  7. Approximate self-consistent potentials for density-functional-theory exchange-correlation functionals

    International Nuclear Information System (INIS)

    Cafiero, Mauricio; Gonzalez, Carlos

    2005-01-01

    We show that potentials for exchange-correlation functionals within the Kohn-Sham density-functional-theory framework may be written as potentials for simpler functionals multiplied by a factor close to unity, and in a self-consistent field calculation, these effective potentials find the correct self-consistent solutions. This simple theory is demonstrated with self-consistent exchange-only calculations of the atomization energies of some small molecules using the Perdew-Kurth-Zupan-Blaha (PKZB) meta-generalized-gradient-approximation (meta-GGA) exchange functional. The atomization energies obtained with our method agree with or surpass previous meta-GGA calculations performed in a non-self-consistent manner. The results of this work suggest the utility of this simple theory to approximate exchange-correlation potentials corresponding to energy functionals too complicated to generate closed forms for their potentials. We hope that this method will encourage the development of complex functionals which have correct boundary conditions and are free of self-interaction errors without the worry that the functionals are too complex to differentiate to obtain potentials

  8. RUSTEC: Greening Europe's energy supply by developing Russia's renewable energy potential

    International Nuclear Information System (INIS)

    Boute, Anatole; Willems, Patrick

    2012-01-01

    The North-West of Russia is characterized by a large renewable energy resource base in geographic proximity to the EU. At the same time, EU Member States are bound by mandatory renewable energy targets which could prove to be costly to achieve in the current budgetary context and which often face strong local opposition. Directive 2009/28/EC on Renewable Energy makes it possible for Member States to achieve their targets by importing electricity produced from renewable energy sources from non-EU countries. So far, most attention has been on the Mediterranean Solar Plan or Desertec. An EU–Russia Renewable Energy Plan or RUSTEC – being based on onshore wind/biomass/hydro energy and on-land interconnection, rather than solar power and subsea lines – could present a cost-efficient and short-term complement to Desertec. This article examines the political, geopolitical, economic, social and legal challenges and opportunities of exporting “green” energy from Russia to the EU. It argues that EU–Russian cooperation in the renewable energy field would present a win-win situation: Member States could achieve their targets on the basis of Russia's renewable energy potential, while Russia could begin to develop a national renewable energy industry without risking potential price increases for domestic consumers—a concern of great political sensitivity in Russia. - Highlights: ► Russia has a huge renewable energy potential in geographic proximity to the EU. ► This potential could help the EU decarbonize its electricity supply at least cost.► EU–Russia green energy export is a win-win situation but lacks political attention.► RUSTEC could be a short-term and cost-efficient complement to Desertec. ► RUSTEC would diversify EU energy imports/Russian exports and stimulate innovation.

  9. STATE SUPPORT FOR DEVELOPMENT OF PERSONNEL POTENTIAL IN HOSPITALITY IN CHINA

    Directory of Open Access Journals (Sweden)

    Yu Yi

    2014-01-01

    Full Text Available The article considers the state support fordevelopment of personnel potential in hospitality business in China. Hospitality frameshave quantitative and qualitative characteristics. The gap between the needs of business organizations of hospitality for highlyqualified personnel at all levels and theirpresence in such a gigantic scale of countriessuch as China, can only be overcome withthe assistance of the state targeted programplanning. Support for human resourcesdevelopment in the hospitality businessincludes directions - the integration of stateformation, educational institutions and businesses. Further step towards improving thecompetitiveness of Chinese tourism shouldbe to develop a national target program fortraining of hospitality

  10. Financial potential and economic development trend of Chuvash Republic, Russian Federation

    Directory of Open Access Journals (Sweden)

    Lyubovtseva E.G.

    2017-01-01

    Full Text Available this article discusses the economic potential and development trend of Chuvash Republic. All important economic indicators of Chuvash Republic like, Gross Regional Production (GRP, employment, export, import, performance of credit organization, per capita income have been taken into consideration to analyze economic performance. This paper also shows how any increase in per capita income effects socio-economic condition. Finally, this paper proposes adequate and proper measures to improve the efficiency and effectiveness in policy formation and use of financial resources in Chuvash Republic on the basis of analysis. Only secondary source of data has been used for analysis.

  11. Surface contact potential patches and Casimir force measurements

    International Nuclear Information System (INIS)

    Kim, W. J.; Sushkov, A. O.; Lamoreaux, S. K.; Dalvit, D. A. R.

    2010-01-01

    We present calculations of contact potential surface patch effects that simplify previous treatments. It is shown that, because of the linearity of Laplace's equation, the presence of patch potentials does not affect an electrostatic calibration of a two-plate Casimir measurement apparatus. Using models that include long-range variations in the contact potential across the plate surfaces, a number of experimental observations can be reproduced and explained. For these models, numerical calculations show that if a voltage is applied between the plates which minimizes the force, a residual electrostatic force persists, and that the minimizing potential varies with distance. The residual force can be described by a fit to a simple two-parameter function involving the minimizing potential and its variation with distance. We show the origin of this residual force by use of a simple parallel capacitor model. Finally, the implications of a residual force that varies in a manner different from 1/d on the accuracy of previous Casimir measurements is discussed.

  12. Technical overview of cogeneration: the hardware, the industries, the potential development

    Energy Technology Data Exchange (ETDEWEB)

    None

    1977-12-01

    Because the by-product heat from a power-conversion process is captured for productive use in a cogeneration system, instead of exhausted to the environment as it is in a conventional power plant, cogeneration represents an important energy-conservation technique. By cogenerating, an industrial plant can save the fuel that would have been needed to produce the amount of heat captured. Recognizing the significant energy-savings potential offered by cogeneration, DOE has undertaken a major R, D, and D program to investigate and promote cogeneration in industry. Resource Planning Associates, Inc. (RPA), has been working to accomplish four of the program's objectives: (1) survey current, near state-of-the-art, and future cogeneration equipment, and identify any gaps or deficiencies; (2) characterize the energy requirements of the manufacturing sectors of five of the country's most energy-intensive industries - chemical, petroleum refining, paper and pulp, textiles, and food; (3) identify principal targets for, and barriers to, the increased market development of cogeneration systems; and (4) estimate the potential maximum and the probable energy savings that could be achieved in the five selected industries through cogeneration. In investigating cogeneration hardware, three specific technologies - steam turbines, gas turbines, and diesel engines - were emphasized. It is estimated that the widespread application of cogeneration technology in the five industries studied could result in a maximum potential savings of 2.4 million barrels of oil equivalent per day (or a maximum incremental capacity of 140,000 MWe) by 1985.

  13. The potential role of sclerostin in the development of osteoarthritis

    DEFF Research Database (Denmark)

    Shen, Jianlin; Lin, S.; Dong, Q

    2016-01-01

    Osteoarthritis (OA), a debilitating degenerative joint disease which is greatly influenced by alterations in the local mechanical loading environment in the joint. The exact aetiology of OA remains unknown, but loss of articular cartilage, subchondral sclerosis, and bone remodeling has been known...... and cartilage/subchondral in both physiological and pathological conditions may lead to development of more effective strategies for treating OA patients. © 2016, E-Century Publishing Corporation. All rights reserved....... of literatures have reported about the relation between Sclerostin and OA. In this review we have tried to summarize the current knowledge on the effect of Sclerostin and to explore the potential role of Sclerostin during the process of OA. A better understanding of the relationship between Sclerostin...

  14. MicroRNA profiling of antler stem cells in potentiated and dormant states and their potential roles in antler regeneration.

    Science.gov (United States)

    Ba, Hengxing; Wang, Datao; Li, Chunyi

    2016-04-01

    MicroRNAs (miRNAs) can effectively regulate gene expression at the post-transcriptional level and play a critical role in tissue growth, development and regeneration. Our previous studies showed that antler regeneration is a stem cell-based process and antler stem cells reside in the periosteum of a pedicle, the permanent bony protuberance, from which antler regeneration takes place. Antlers are the only mammalian organ that can fully regenerate and hence provide a unique opportunity to identify miRNAs that are involved in organ regeneration. In the present study, we used next generation sequencing technology sequenced miRNAs of the stem cells derived from either the potentiated or the dormant pedicle periosteum. A population of both conserved and 20 deer-specific miRNAs was identified. These conserved miRNAs were derived from 453 homologous hairpin precursors across 88 animal species, and were further grouped into 167 miRNA families. Among them, the miR-296 is embryonic stem cell-specific. The potentiation process resulted in the significant regulation (>±2 Fold, q value cell potentiation process. This research has identified miRNAs that are associated either with the dormant or the potentiated antler stem cells and identified some target miRNAs for further research into their role played in mammalian organ regeneration.

  15. Potentials of biofuels

    Energy Technology Data Exchange (ETDEWEB)

    Munack, A.; Schroder, O. [Johann Heinrich von Thunen Inst., Braunschweig (Germany); Krahl, J. [Coburg Univ. of Applied Sciences, Coburg (Germany); Bunger, J. [Inst. for Prevention and Occupational Medicine of the German Social Accident Insurance, Ruhr-Univ. Inst., Bochum (Germany)

    2010-07-01

    This paper discussed the potential of biofuels with particular reference to the situation in Germany and Europe. Emphasis was on technical potential, such as biofuel production, utilization and environmental aspects. The Institute of Agricultural Technology and Biosystems Engineering ran vTI emission tests on diesel engines to evaluate the environmental impacts of biofuels. This testing facility is able to drive heavy-duty diesel engines in both stationary and dynamic test cycles, such as the European ESC and ETC. Additional analyses were conducted to determine the fine and ultra-fine particles, polycyclic aromatic hydrocarbons (PAH), aldehydes, ketones, and the usual regulated exhaust gas compounds. Ames tests were conducted to assess the mutagenic potential of tailpipe emissions. Previous study results showed that neat vegetable oils can render the exhaust high in mutagenic potency. Some of the non-regulated exhaust gas compounds were found to vary nonlinearly with the blend composition. B20 was found to have high mutagenic potential and was subject to sedimentation.

  16. INNOVATION POTENTIAL OF RUSSIAN NORTHERN REGIONS: DEVELOPMENT TRENDS

    Directory of Open Access Journals (Sweden)

    E.N. Berezikova

    2008-06-01

    Full Text Available In the work for the first time a methodology of complex evaluation of innovation potentials of the regions is proposed. As a result the index of innovation potentials of Russian northern regions was determined, and on its basis all regions are referred to groups corresponding their innovation rating. A system of measures on stimulation of innovation activities in regions has been proposed

  17. Developments in mercuric iodide gamma ray imaging

    Energy Technology Data Exchange (ETDEWEB)

    Patt, B E; Beyerle, A G; Dolin, R C; Ortale, C [EG and G Energy Measurements, Inc., Goleta, CA (USA). Santa Barbara Operations

    1989-11-01

    A mercuric iodide (HgI{sub 2}) gamma ray imaging array and camera system previously described have been characterized for spatial and energy resolution. Based on these data a new camera is being developed to more fully exploit the potential of the array. Characterization results and design criteria for the new camera will be presented. (orig.).

  18. Essential multimeric enzymes in kinetoplastid parasites: A host of potentially druggable protein-protein interactions.

    Science.gov (United States)

    Wachsmuth, Leah M; Johnson, Meredith G; Gavenonis, Jason

    2017-06-01

    Parasitic diseases caused by kinetoplastid parasites of the genera Trypanosoma and Leishmania are an urgent public health crisis in the developing world. These closely related species possess a number of multimeric enzymes in highly conserved pathways involved in vital functions, such as redox homeostasis and nucleotide synthesis. Computational alanine scanning of these protein-protein interfaces has revealed a host of potentially ligandable sites on several established and emerging anti-parasitic drug targets. Analysis of interfaces with multiple clustered hotspots has suggested several potentially inhibitable protein-protein interactions that may have been overlooked by previous large-scale analyses focusing solely on secondary structure. These protein-protein interactions provide a promising lead for the development of new peptide and macrocycle inhibitors of these enzymes.

  19. A previous hamstring injury affects kicking mechanics in soccer players.

    Science.gov (United States)

    Navandar, Archit; Veiga, Santiago; Torres, Gonzalo; Chorro, David; Navarro, Enrique

    2018-01-10

    Although the kicking skill is influenced by limb dominance and sex, how a previous hamstring injury affects kicking has not been studied in detail. Thus, the objective of this study was to evaluate the effect of sex and limb dominance on kicking in limbs with and without a previous hamstring injury. 45 professional players (males: n=19, previously injured players=4, age=21.16 ± 2.00 years; females: n=19, previously injured players=10, age=22.15 ± 4.50 years) performed 5 kicks each with their preferred and non-preferred limb at a target 7m away, which were recorded with a three-dimensional motion capture system. Kinematic and kinetic variables were extracted for the backswing, leg cocking, leg acceleration and follow through phases. A shorter backswing (20.20 ± 3.49% vs 25.64 ± 4.57%), and differences in knee flexion angle (58 ± 10o vs 72 ± 14o) and hip flexion velocity (8 ± 0rad/s vs 10 ± 2rad/s) were observed in previously injured, non-preferred limb kicks for females. A lower peak hip linear velocity (3.50 ± 0.84m/s vs 4.10 ± 0.45m/s) was observed in previously injured, preferred limb kicks of females. These differences occurred in the backswing and leg-cocking phases where the hamstring muscles were the most active. A variation in the functioning of the hamstring muscles and that of the gluteus maximus and iliopsoas in the case of a previous injury could account for the differences observed in the kicking pattern. Therefore, the effects of a previous hamstring injury must be considered while designing rehabilitation programs to re-educate kicking movement.

  20. Development of GIS-based Wind Potential Map of Makkah Province, Saudi Arabia

    Science.gov (United States)

    Nayyar, Z. A.; Zaigham, N. A.; Aburizaiza, O. S.; Mahar, G. A.; Eusufi, S. N.

    2011-12-01

    Global energy scenario is changing drastically toward decline, as new major discoveries of fossil fuel are not coming up significantly on regional basis. In case of Saudi Arabia, one of the largest fossil fuel producers, the major oil fields have started exhausting significantly as revealed from the literature research study. Considering the future energy crisis, different other renewable options presently have became imperative to be consider anticipating for the national development. Wind energy in one of them. The development of wind energy technology requires the baseline data relevant to the wind trends and their potentials. Under the present study, an attempt has been made to develop wind power density map of the Makkah Province of Saudi Arabia based on the meteorological data collected at different sparsely located weather stations. GIS application has provided a good option to interpolate the gap areas between the sparsely located weather recording stations. This paper describe the methodology and results of the present study.

  1. An automated patient recognition method based on an image-matching technique using previous chest radiographs in the picture archiving and communication system environment

    International Nuclear Information System (INIS)

    Morishita, Junji; Katsuragawa, Shigehiko; Kondo, Keisuke; Doi, Kunio

    2001-01-01

    An automated patient recognition method for correcting 'wrong' chest radiographs being stored in a picture archiving and communication system (PACS) environment has been developed. The method is based on an image-matching technique that uses previous chest radiographs. For identification of a 'wrong' patient, the correlation value was determined for a previous image of a patient and a new, current image of the presumed corresponding patient. The current image was shifted horizontally and vertically and rotated, so that we could determine the best match between the two images. The results indicated that the correlation values between the current and previous images for the same, 'correct' patients were generally greater than those for different, 'wrong' patients. Although the two histograms for the same patient and for different patients overlapped at correlation values greater than 0.80, most parts of the histograms were separated. The correlation value was compared with a threshold value that was determined based on an analysis of the histograms of correlation values obtained for the same patient and for different patients. If the current image is considered potentially to belong to a 'wrong' patient, then a warning sign with the probability for a 'wrong' patient is provided to alert radiology personnel. Our results indicate that at least half of the 'wrong' images in our database can be identified correctly with the method described in this study. The overall performance in terms of a receiver operating characteristic curve showed a high performance of the system. The results also indicate that some readings of 'wrong' images for a given patient in the PACS environment can be prevented by use of the method we developed. Therefore an automated warning system for patient recognition would be useful in correcting 'wrong' images being stored in the PACS environment

  2. Comprehensive simulation study on local and global development of auroral arcs and field-aligned potentials

    International Nuclear Information System (INIS)

    Watanabe, Tomohiko; Oya, Hiroshi; Watanabe, Kunihiko; Sato, Tetsuya.

    1992-10-01

    Extensive three-dimensional computer simulations of the magnetosphere-ionosphere (M-I) coupling are performed to study self-excitation of auroral arcs with special emphasis on 1) nonlinear evolution of the feedback instability in the M-I coupling system, 2) controlling mechanisms of the auroral arc structure, 3) formation of a field-aligned electric potential structure in association with the development of the feedback instability, and 4) effects of the parallel potential generation on auroral arc development. It is reconfirmed that the feedback instability produces a longitudinally elongated, latitudinally striated structure where the upward field-aligned current and the ionospheric density are locally enhanced. The following important new features are revealed. 1) The global distribution of the striation structure is primarily governed by the magnetospheric convection pattern and the ionospheric density distribution. 2) There appears a significant dawn-dusk asymmetry in the auroral arc formation, even though the apparent geometrical relationship is symmetric. 3) The recombination effect plays a significant role in the global, as well as local, development of the auroral arc structure. The nonlinearity of recombination, in conjunction with the closure of an arc-associated local field-aligned current system, acts to destroy an old arc and creates a new arc in a different but adjacent position. 4) A V-shaped field aligned potential structure is created in association with an auroral arc. Rapid increase in the electron density and the local upward field-aligned current of an arc arises as a result of enhanced ionization by precipitating electrons accelerated by the parallel potential. 5) A drastic oscillatory behavior of appearance and disappearance of auroral arcs is obtained when the ionization effect is strong. The period is primarily given by the Alfven bounce time. (J.P.N.)

  3. Time Eigenstates for Potential Functions without Extremal Points

    Directory of Open Access Journals (Sweden)

    Gabino Torres-Vega

    2013-09-01

    Full Text Available In a previous paper, we introduced a way to generate a time coordinate system for classical and quantum systems when the potential function has extremal points. In this paper, we deal with the case in which the potential function has no extremal points at all, and we illustrate the method with the harmonic and linear potentials.

  4. Potential Development of Bioindustry in Cattle and Oil Palm Integration System

    Directory of Open Access Journals (Sweden)

    Gunawan

    2014-06-01

    Full Text Available An integrated system between cattle and oil palm plantation has a great potency for development of bioindustry, either in the form of animal feed or organic fertilizer bioindustry. Bioindustry of cattle feed is developed from biomass of plantations, such as stem and leaves of palm, palm kernel and solid. Bioindustry of organic fertilizer is developed from cattle manure. The targets of development of bioindustry are palm plantations in Sumatera and Kalimantan regions, covering 9.25 million hectares. It is estimated to be able to produce biomass quantity as much as 54.60 million tons per year which can be used as fodder for 12.13 million animal unit (AU of beef cattle, whereas currently there are only 3.06 million AU cattle in Sumatera and Kalimantan, so the opportunities for the addition of cattle in both islands are 9.07 million AU. The existing beef cattle population of 3.06 million AU has the potency to produce 6.1 million tons of organic fertilizer can be used to fertilize 3.0 million hectares, therefore the rest of 6.25 million hectares remain unfertilised. The prospect of bioindustries on integration system of cattle with oil palm plantations in Sumatera and Kalimantan is very potential to meet the needs of organic fertilizer for plants and to utilize oil palm biomass for cattle feed.

  5. Migratory behavior and physiological development as potential determinants of life history diversity in fall Chinook Salmon in the Clearwater River

    Science.gov (United States)

    Tiffan, Kenneth F.; Kock, Tobias J.; Connor, William P.; Richmond, Marshall C.; Perkins, William A.

    2018-01-01

    We studied the influence of behavior, water velocity, and physiological development on the downstream movement of subyearling fall‐run Chinook Salmon Oncorhynchus tshawytscha in both free‐flowing and impounded reaches of the Clearwater and Snake rivers as potential mechanisms that might explain life history diversity in this stock. Movement rates and the percentage of radio‐tagged fish that moved faster than the average current velocity were higher in the free‐flowing Clearwater River than in impounded reaches. This supports the notion that water velocity is a primary determinant of downstream movement regardless of a fish's physiological development. In contrast, movement rates slowed and detections became fewer in impounded reaches, where water velocities were much lower. The percentage of fish that moved faster than the average current velocity continued to decline and reached zero in the lowermost reach of Lower Granite Reservoir, suggesting that the behavioral disposition to move downstream was low. These findings contrast with those of a similar, previous study of Snake River subyearlings despite similarity in hydrodynamic conditions between the two studies. Physiological differences between Snake and Clearwater River migrants shed light on this disparity. Subyearlings from the Clearwater River were parr‐like in their development and never showed the increase in gill Na+/K+‐ATPase activity displayed by smolts from the Snake River. Results from this study provide evidence that behavioral and life history differences between Snake and Clearwater River subyearlings may have a physiological basis that is modified by environmental conditions.

  6. Study on the nonlocality effects for generalized optical potentials

    International Nuclear Information System (INIS)

    Gurbanovich, I.S.; Zelenskaya, N.S.

    1981-01-01

    In previous studies the authors have ihown that the generalized optic potential (GOP) of particles interaction is a superposition of local and non local potentials (LP, NLP). On the example of α- particles scattering on the 8 Be nucleus at about 10-15 MeV the GOP nonlocal part is considered. For obtaining NLP the spectral decomposition of the Green function taking into account only contribution of relative motion of two α-particles in S-state is used. The locally-equivalent addition to central potential of α-particles scattering at 8 Be previously calculated is obtained. In a graphical form a total locally-equivalent potential and local GOP part are presented. It is shown that taking into account the nonlocallity effect in a locally energy approximation for precise wave function in S-state widen a potential hole without changing its depth. Such widening corresponds to the general character of behaviour of non local potentials calculated in the microscopic approach [ru

  7. Rhabdomyosarcoma Arising in a Previously Irradiated Field: An Analysis of 43 Patients

    Energy Technology Data Exchange (ETDEWEB)

    Dang, Nguyen D. [Department of Radiation Oncology, Baylor College of Medicine, Houston, Texas (United States); Teh, Bin S. [Department of Radiation Oncology, The Methodist Hospital and Methodist Hospital Research Institute, Houston, Texas (United States); Paulino, Arnold C., E-mail: apaulino@tmhs.org [Department of Radiation Oncology, The Methodist Hospital and Methodist Hospital Research Institute, Houston, Texas (United States)

    2013-03-01

    Patients with soft tissue sarcomas that arise from previously irradiated fields have traditionally been reported to have a poor prognosis. In this report, we examined the characteristics and outcomes of patients who developed a rhabdomyosarcoma in a previously irradiated field (RMS-RIF); we hypothesize that these patients should have a better outcome compared to other postradiation soft tissue sarcomas as these tumors are chemosensitive and radiosensitive. A PubMed search of the literature from 1961-2010 yielded 33 studies with data for patients with RMS-RIF. The study included 43 patients with a median age of 6.5 years at the time of radiation therapy (RT) for the initial tumor. The median RT dose was 48 Gy. The median latency period, the time from RT to development of RMS-RIF, was 8 years. The 3-year overall survival for RMS-RIF was 42%. The 3-year overall survival was 66% for patients receiving chemotherapy and local treatment (surgery and/or RT) compared to 29% for those who had systemic treatment only or local treatment only (P=.049). Other factors associated with increased 3-year overall survival included retinoblastoma initial diagnosis (P<.001), age ≤18 years at diagnosis of RMS-RIF (P=.003), favorable site (P=.008), and stage 1 disease (P=.002). Age at time of RMS-RIF, retinoblastoma initial tumor, favorable site, stage 1 disease, and use of both systemic and local treatment were found to be favorable prognostic factors for 3-year overall survival.

  8. Preinflationary dynamics in loop quantum cosmology: Power-law potentials

    Science.gov (United States)

    Shahalam, M.; Sharma, Manabendra; Wu, Qiang; Wang, Anzhong

    2017-12-01

    In this paper, we study the preinflationary dynamics for the power-law potential [V (ϕ )∝ϕn] with n consideration and compare our results with the ones obtained previously for different potentials.

  9. Developing index maps of water-harvest potential in Africa

    Science.gov (United States)

    Senay, G.B.; Verdin, J.P.

    2004-01-01

    The food security problem in Africa is tied to the small farmer, whose subsistence farming relies heavily on rain-fed agriculture. A dry spell lasting two to three weeks can cause a significant yield reduction. A small-scale irrigation scheme from small-capacity ponds can alleviate this problem. This solution would require a water harvest mechanism at a farm level. In this study, we looked at the feasibility of implementing such a water harvest mechanism in drought prone parts of Africa. A water balance study was conducted at different watershed levels. Runoff (watershed yield) was estimated using the SCS curve number technique and satellite derived rainfall estimates (RFE). Watersheds were delineated from the Africa-wide HYDRO-1K digital elevation model (DEM) data set in a GIS environment. Annual runoff volumes that can potentially be stored in a pond during storm events were estimated as the product of the watershed area and runoff excess estimated from the SCS Curve Number method. Estimates were made for seepage and net evaporation losses. A series of water harvest index maps were developed based on a combination of factors that took into account the availability of runoff, evaporation losses, population density, and the required watershed size needed to fill a small storage reservoir that can be used to alleviate water stress during a crop growing season. This study presents Africa-wide water-harvest index maps that could be used for conducting feasibility studies at a regional scale in assessing the relative differences in runoff potential between regions for the possibility of using ponds as a water management tool. ?? 2004 American Society of Agricultural Engineers.

  10. Study of methanization resource and potential development in Aquitaine - Technical report. To keep on developing the methanization sector in the Dordogne district

    International Nuclear Information System (INIS)

    Priarollo, Jeremie; Michels, Julie; Jimenez, Julien

    2015-05-01

    This study aims at characterising territories of the Aquitaine region in terms of potential of development of individual, collective and territorial methanization units. The territory organic resource potential has first been assessed, and then combined with energetic outlets for biogas and outlets for digestates. A first phase aimed at providing a situational analysis of the methanization sector in the region. During a second phase, different resources of mobilisable organic wastes have been quantified, characterised and mapped at the district level in combination with energetic outlets (gas and heat) and digestate outlets. A third phase aimed at identifying and characterising areas of the different districts of the region displaying a methanization potential. After this report, a set of Power Point presentations is proposed which present this study under another form. Thus, these presentations contain graphs and data which illustrate these different aspects and issues: presentation of the different methanizable resources (quantitative results and maps), energy valorisation potential (co-generation and thermal outlets, injection into natural gas networks, definition and characterisation of areas displaying an interesting potential), presentation of a regional support arrangement (Methaqtion)

  11. Developing leadership as a trainee- opportunities, barriers and potential improvements.

    Science.gov (United States)

    Doherty, Rachel; Lawson, Sara; Mc Laughlin, Laura; Donaghy, Grainne; Courtney, Julia; Gardiner, Keith

    2018-05-01

    The General Medical Council explicitly state that doctors completing training should demonstrate capabilities in leadership and teamwork. 1 However, most trainees receive little formal training in leadership. In March 2017, at the Faculty of Medical Leadership and Management (FMLM) Northern Ireland Regional Conference, a workshop on developing leadership skills as a trainee was hosted and the views of doctors in training regarding current opportunities, potential barriers and improvements were sought. In Northern Ireland presently there are a number of opportunities available for trainees to gain experience in leadership - both by learning through observation and learning through experience. These range from informal activities which do not require significant time commitment to focused, immersive leadership experiences such as ADEPT (Achieve Develop Explore Programme for Trainees) 2 , and the Royal College of Physicians' Chief Registrar scheme. 3 Several barriers to developing leadership have been identified, including limited understanding of what constitutes leadership, a lack of senior support and little formal recognition for trainees leading teams. Time pressures, frequently rotating jobs, limited resources and difficulty upscaling can also undermine the sustainability of improvement and other leadership projects. Incorporating awareness of and training in leadership skills, as well as greater engagement with senior leaders and managers, at an early stage in training could promote understanding and encourage trainees. Formalising leadership roles within training posts may improve experience. Deaneries and Trusts can also enable leadership opportunities by facilitating study leave, raising awareness amongst supervisors, and providing career enhancing incentives for interested trainees.

  12. Potential of beta-adrenergic agonists for increasing protein deposition in ruminants in developing countries

    International Nuclear Information System (INIS)

    Berschauer, F.

    1989-01-01

    Various substituted phenylethanolamines, acting on the sympathetic nervous system, have been shown to increase protein retention (via decreased proteolysis) and reduce fat deposition (via increased lipolysis and reduced lipogenesis) in ruminants and monogastrics. Research with finishing lambs in developed countries show various beta-adrenergic agonists to improve growth rate (by 18%), feed conversion (by 12%) and carcass quality (28% increase in area of longissimus dorsi and 33% reduction in subcutaneous fat). Similar effects of beta-agonists on carcass composition of well fed cattle have been reported. The effects of beta-agonists on livestock in developing countries of the tropics have not yet been investigated, but their effects in increasing metabolic rate suggest that treated ruminants would be more vulnerable to hot environments. Beta-agonists appear to improve nitrogen retention to a greater extent in breeds with a lower potential for muscle growth. In view of this, they might be particularly effective in improving nitrogen retention in tropical breeds which have a low growth potential. This aspect, together with the response of undernourished animals in the developing countries, needs investigation. Beta-adrenergic agonists are not yet registered for use in animal production, but product licenses for some of them are expected to be granted soon. (author). 31 refs, 1 fig., 12 tabs

  13. Influence of Previous Knowledge, Language Skills and Domain-specific Interest on Observation Competency

    Science.gov (United States)

    Kohlhauf, Lucia; Rutke, Ulrike; Neuhaus, Birgit

    2011-10-01

    Many epoch-making biological discoveries (e.g. Darwinian Theory) were based upon observations. Nevertheless, observation is often regarded as `just looking' rather than a basic scientific skill. As observation is one of the main research methods in biological sciences, it must be considered as an independent research method and systematic practice of this method is necessary. Because observation skills form the basis of further scientific methods (e.g. experiments or comparisons) and children from the age of 4 years are able to independently generate questions and hypotheses, it seems possible to foster observation competency at a preschool level. To be able to provide development-adequate individual fostering of this competency, it is first necessary to assess each child's competency. Therefore, drawing on the recent literature, we developed in this study a competency model that was empirically evaluated within learners ( N = 110) from different age groups, from kindergarten to university. In addition, we collected data on language skills, domain-specific interest and previous knowledge to analyse coherence between these skills and observation competency. The study showed as expected that previous knowledge had a high impact on observation competency, whereas the influence of domain-specific interest was nonexistent. Language skills were shown to have a weak influence. By utilising the empirically validated model consisting of three dimensions (`Describing', `Scientific reasoning' and `Interpreting') and three skill levels, it was possible to assess each child's competency level and to develop and evaluate guided play activities to individually foster a child's observation competency.

  14. Evaluation of an interdisciplinary re-isolation policy for patients with previous Clostridium difficile diarrhea.

    Science.gov (United States)

    Boone, N; Eagan, J A; Gillern, P; Armstrong, D; Sepkowitz, K A

    1998-12-01

    difficile required interdisciplinary cooperation between infection control and the admitting department. By identifying patients who were positive for toxin through admitting, we were able to place all potentially infected patients into isolation. Our positivity rate of 15% on readmission demonstrates the importance of this policy. The cost of controlling C difficile can be significantly lowered by clearing patients who were previously positive for toxin before hospital readmission.

  15. Potential implementation of light steel housing system for affordable housing project in Malaysia

    Science.gov (United States)

    Saikah, M.; Kasim, N.; Zainal, R.; Sarpin, N.; Rahim, M. H. I. A.

    2017-11-01

    An unparalleled number between housing demand and housing supply in Malaysia has increased the housing prices, which gives consequences to the homeownership issue. One way to reduce the housing price is by faster increase the number of affordable housing, but the construction sector faces difficulties in delivering as expected number by using conventional and current industrialised building system (IBS) due to the issue related high project cost, time and labour. Therefore, light steel housing (LSH) system as one of another type of IBS method can be utilised in housing construction project. This method can replace the conventional method that was currently used in the construction of affordable housing project. The objectives of this study are to identify the potential of LSH and influencing factors of system implementation. This is an initial stage to review the previous study related to LSH implementation in developed and developing countries. The previous study will be analysed regarding advantages and disadvantages of LSH and factors that influence the implementation of the system. Based on the literature review it is expected to define the potential and influencing factors of the LSH system. The findings are meaningful in framing and enhance construction housing method of an affordable housing project in Malaysia.

  16. A longitudinal study of plasma insulin and glucagon in women with previous gestational diabetes

    DEFF Research Database (Denmark)

    Damm, P; Kühl, C; Hornnes, P

    1995-01-01

    OBJECTIVE: To investigate whether plasma insulin or glucagon predicts later development of diabetes in women with gestational diabetes mellitus (GDM). RESEARCH DESIGN AND METHODS: The subjects studied were 91 women with diet-treated GDM and 33 healthy women. Plasma insulin and glucagon during a 50...... at follow-up (2 had insulin-dependent diabetes mellitus, 13 had non-insulin-dependent diabetes mellitus, and 12 had impaired glucose tolerance). Compared with the control subjects, women with previous GDM had relatively impaired insulin secretion (decreased insulinogenic index and delayed peak insulin...... for subsequent development of overt diabetes (logistic regression analysis). CONCLUSIONS: Women who develop GDM have a relative insulin secretion deficiency, the severity of which is predictive for later development of diabetes. Furthermore, our data indicate that their relatively reduced beta-cell function may...

  17. Previously unknown species of Aspergillus.

    Science.gov (United States)

    Gautier, M; Normand, A-C; Ranque, S

    2016-08-01

    The use of multi-locus DNA sequence analysis has led to the description of previously unknown 'cryptic' Aspergillus species, whereas classical morphology-based identification of Aspergillus remains limited to the section or species-complex level. The current literature highlights two main features concerning these 'cryptic' Aspergillus species. First, the prevalence of such species in clinical samples is relatively high compared with emergent filamentous fungal taxa such as Mucorales, Scedosporium or Fusarium. Second, it is clearly important to identify these species in the clinical laboratory because of the high frequency of antifungal drug-resistant isolates of such Aspergillus species. Matrix-assisted laser desorption/ionization-time of flight mass spectrometry (MALDI-TOF MS) has recently been shown to enable the identification of filamentous fungi with an accuracy similar to that of DNA sequence-based methods. As MALDI-TOF MS is well suited to the routine clinical laboratory workflow, it facilitates the identification of these 'cryptic' Aspergillus species at the routine mycology bench. The rapid establishment of enhanced filamentous fungi identification facilities will lead to a better understanding of the epidemiology and clinical importance of these emerging Aspergillus species. Based on routine MALDI-TOF MS-based identification results, we provide original insights into the key interpretation issues of a positive Aspergillus culture from a clinical sample. Which ubiquitous species that are frequently isolated from air samples are rarely involved in human invasive disease? Can both the species and the type of biological sample indicate Aspergillus carriage, colonization or infection in a patient? Highly accurate routine filamentous fungi identification is central to enhance the understanding of these previously unknown Aspergillus species, with a vital impact on further improved patient care. Copyright © 2016 European Society of Clinical Microbiology and

  18. Deriving muscle fiber diameter from recorded single fiber potential.

    Science.gov (United States)

    Zalewska, Ewa

    2017-12-01

    The aim of the study was to estimate muscle fiber diameters through analysis of single muscle fiber potentials (SFPs) recorded in the frontalis muscle of a healthy subject. Our previously developed analytical and graphic method to derive fiber diameter from the analysis of the negative peak duration and the amplitude of SFP, was applied to a sample of ten SFPs recorded in vivo. Muscle fiber diameters derived from the simulation method for the sample of frontalis muscle SFPs are consistent with anatomical data for this muscle. The results confirm the utility of proposed simulation method. Outlying data could be considered as the result of a contribution of other fibers to the potential recorded using an SFEMG electrode. Our graphic tool provides a rapid estimation of muscle fiber diameter. Copyright © 2017 Elsevier Masson SAS. All rights reserved.

  19. The tachyon potential in string theory

    International Nuclear Information System (INIS)

    Banks, T.

    1991-01-01

    We argue that the tachyon potential in string theory is exactly given by the unstable quadratic mass term calculated perturbatively around the critical string. The argument is given in terms of the sigma model formulation. The same result follows from the exact Wilson renormalization group equations. The discrepancy with previous calculations of the tachyon potential is explained by the fact that other authors worked near the tachyon mass shell where it is impossible to distinguish a potential from derivative terms in the effective action. (orig.)

  20. Development and optimization of a cell-based assay for the selection of synthetic compounds that potentiate bone morphogenetic protein-2 activity.

    Science.gov (United States)

    Okada, Motohiro; Sangadala, Sreedhara; Liu, Yunshan; Yoshida, Munehito; Reddy, Boojala Vijay B; Titus, Louisa; Boden, Scott D

    2009-12-01

    The requirement of large amounts of the recombinant human bone morphogenetic protein-2 (BMP-2) produces a huge translational barrier for its routine clinical use due to high cost. This leads to an urgent need to develop alternative methods to lower costs and/or increase efficacies for using BMP-2. In this study, we describe the development and optimization of a cell-based assay that is sensitive, reproducible, and reliable in identifying reagents that potentiate the effects of BMP-2 in inducing transdifferentiation of C2C12 myoblasts into the osteoblastic phenotype. The assay is based on a BMP-responsive Smad1-driven luciferase reporter gene. LIM mineralization protein-1 (LMP-1) is a novel intracellular LIM domain protein that has been shown by our group to enhance cellular responsiveness to BMP-2. Our previous report elucidated that the binding of LMP-1 with the WW2 domain in Smad ubiquitin regulatory factor-1 (Smurf1) rescues the osteogenic Smads from degradation. Here, using the optimized cell-based assay, we first evaluated the activity of the recombinantly prepared proteins, LMP-1, and its mutant (LMP-1DeltaSmurf1) that lacks the Smurf1-WW2 domain-binding motif. Both the wild type and the mutant proteins were engineered to contain an 11-amino acid HIV-TAT protein derived membrane transduction domain to aid the cellular delivery of recombinant proteins. The cell-based reporter assay confirmed that LMP-1 potentiates the BMP-induced stimulation of C2C12 cells towards the osteoblastic phenotype. The potentiating effect of LMP-1 was significantly reduced when a specific-motif known to interact with Smurf1 was mutated. We validated the results obtained in the reporter assay by also monitoring the expression of mRNA for osteocalcin and alkaline phosphatase (ALP) which is widely accepted osteoblast differentiation marker genes. Finally, we provide further confirmation of our results by measuring the activity of alkaline phosphatase in support of the accuracy and

  1. Using Event-Related Potentials to Study Perinatal Nutrition and Brain Development in Infants of Diabetic Mothers

    OpenAIRE

    deRegnier, Raye-Ann; Long, Jeffrey D.; Georgieff, Michael K.; Nelson, Charles A.

    2007-01-01

    Proper prenatal and postnatal nutrition is essential for optimal brain development and function. The early use of event-related potentials enables neuroscientists to study the development of cognitive function from birth and to evaluate the role of specific nutrients in development. Perinatal iron deficiency occurs in severely affected infants of diabetic mothers. In animal models, severe perinatal iron deficiency targets the explicit memory system of the brain. Cross-sectional ERP studies ha...

  2. Methodology developed to make the Quebec indoor radon potential map

    International Nuclear Information System (INIS)

    Drolet, Jean-Philippe; Martel, Richard; Poulin, Patrick; Dessau, Jean-Claude

    2014-01-01

    This paper presents a relevant approach to predict the indoor radon potential based on the combination of the radiogeochemical data and the indoor radon measurements in the Quebec province territory (Canada). The Quebec ministry of health asked for such a map to identify the radon-prone areas to manage the risk for the population related to indoor radon exposure. Three radiogeochemical criteria including (1) equivalent uranium (eU) concentration from airborne surface gamma-ray surveys, (2) uranium concentration measurements in sediments, (3) bedrock and surficial geology were combined with 3082 basement radon concentration measurements to identify the radon-prone areas. It was shown that it is possible to determine thresholds for the three criteria that implied statistically significant different levels of radon potential using Kruskal–Wallis one way analyses of variance by ranks. The three discretized radiogeochemical datasets were combined into a total predicted radon potential that sampled 98% of the studied area. The combination process was also based on Kruskal–Wallis one way ANOVA. Four statistically significant different predicted radon potential levels were created: low, medium, high and very high. Respectively 10 and 13% of the dwellings exceed the Canadian radon guideline of 200 Bq/m 3 in low and medium predicted radon potentials. These proportions rise up to 22 and 45% respectively for high and very high predicted radon potentials. This predictive map of indoor radon potential based on the radiogeochemical data was validated using a map of confirmed radon exposure in homes based on the basement radon measurements. It was shown that the map of predicted radon potential based on the radiogeochemical data was reliable to identify radon-prone areas even in zones where no indoor radon measurement exists. - Highlights: • 5 radiogeochemical datasets were used to map the geogenic indoor radon potential. • An indoor radon potential was determined for each

  3. Cellulosic ethanol. Potential, technology and development status

    Energy Technology Data Exchange (ETDEWEB)

    Rarbach, M. [Sued-Chemie AG, Muenchen (Germany)

    2012-07-01

    In times of rising oil prices and a growing energy demand, sustainable alternative energy sources are needed. Cellulosic ethanol is a sustainable biofuel, made from lignocellulosic feedstock such as agricultural residues (corn stover, cereal straw, bagasse) or dedicated energy crops. Its production is almost carbon neutral, doesn't compete with food or feed production and induces no land use changes. It constitutes a new energy source using an already existing renewable feedstock without needing any further production capacity and can thus play a major role on the way to more sustainability in transport and the chemical industry and reducing the dependence on the import of fossil resources. The potential for cellulosic ethanol is huge: In the US, the annual production of agricultural residues (cereal straw and corn stover) reached almost 384 million tons in 2009 and Brazil alone produced more than 670 million tons of sugar cane in 2009 yielding more than 100 million tons of bagasse (dry basis). And alone in the European Union, almost 300 million tons of crop straw are produced annually. The last years have seen success in the development and deployment in the field of cellulosic ethanol production. The main challenge thereby remains to demonstrate that the technology is economically feasible for the up-scaling to industrial scale. Clariant has developed the sunliquid {sup registered} process, a proprietary cellulosic ethanol technology that reaches highest greenhouse gas (GHG) emission savings while cutting production costs to a minimum. The sunliquid {sup registered} process for cellulosic ethanol matches the ambitious targets for economically and ecologically sustainable production and greenhouse gas reduction. It was developed using an integrated design concept. Highly optimized, feedstock and process specific biocatalysts and microorganisms ensure a highly efficient process with improved yields and feedstock-driven production costs. Integrated, on

  4. The patents-based pharmaceutical development process: rationale, problems, and potential reforms.

    Science.gov (United States)

    Barton, John H; Emanuel, Ezekiel J

    2005-10-26

    The pharmaceutical industry is facing substantial criticism from many directions, including financial barriers to access to drugs in both developed and developing countries, high profits, spending on advertising and marketing, and other issues. Underlying these criticisms are fundamental questions about the value of the current patent-based drug development system. Six major problems with the patent system are (1) recovery of research costs by patent monopoly reduces access to drugs; (2) market demand rather than health needs determines research priorities; (3) resources between research and marketing are misallocated; (4) the market for drugs has inherent market failures; (5) overall investment in drug research and development is too low, compared with profits; and (6) the existing system discriminates against US patients. Potential solutions fall into 3 categories: change in drug pricing through either price controls or tiered pricing; change in drug industry structure through a "buy-out" pricing system or with the public sector acting as exclusive research funder; and change in development incentives through a disease burden incentive system, orphan drug approaches, or requiring new drugs to demonstrate improvement over existing products prior to US Food and Drug Administration approval. We recommend 4 complementary reforms: (1) having no requirement to test new drug products against existing products prior to approval but requiring rigorous comparative postapproval testing; (2) international tiered pricing and systematic safeguards to prevent flow-back; (3) increased government-funded research and buy-out for select conditions; and (4) targeted experiments using other approaches for health conditions in which there has been little progress and innovation over the last few decades.

  5. Assessment of market potential of compressed air energy storage systems

    Science.gov (United States)

    Boyd, D. W.; Buckley, O. E.; Clark, C. E., Jr.

    1983-12-01

    This report describes an assessment of potential roles that EPRI might take to facilitate the commercial acceptance of compressed air energy storage (CAES) systems. The assessment is based on (1) detailed analyses of the market potential of utility storage technologies, (2) interviews with representatives of key participants in the CAES market, and (3) a decision analysis synthesizing much of the information about market and technology status. The results indicate a large potential market for CAES systems if the overall business environment for utilities improves. In addition, it appears that EPRI can have a valuable incremental impact in ensuring that utilities realize the potential of CAES by (1) continuing an aggressive information dissemination and technology transfer program, (2) working to ensure the success of the first United States CAES installation at Soyland Power Cooperative, (3) developing planning methods to allow utilities to evaluate CAES and other storage options more effectively and more realistically, and (4) supporting R and D to resolve residual uncertainties in first-generation CAES cost and performance characteristics. Previously announced in STAR as N83-25121

  6. Trial of labour and vaginal birth after previous caesarean section: A population based study of Eastern African immigrants in Victoria, Australia.

    Science.gov (United States)

    Belihu, Fetene B; Small, Rhonda; Davey, Mary-Ann

    2017-03-01

    Variations in caesarean section (CS) between some immigrant groups and receiving country populations have been widely reported. Often, African immigrant women are at higher risk of CS than the receiving population in developed countries. However, evidence about subsequent mode of birth following CS for African women post-migration is lacking. The objective of this study was to examine differences in attempted and successful vaginal birth after previous caesarean (VBAC) for Eastern African immigrants (Eritrea, Ethiopia, Somalia and Sudan) compared with Australian-born women. A population-based observational study was conducted using the Victorian Perinatal Data Collection. Pearson's chi-square test and logistic regression analysis were performed to generate adjusted odds ratios for attempted and successful VBAC. Victoria, Australia. 554 Eastern African immigrants and 24,587 Australian-born eligible women with previous CS having singleton births in public care. 41.5% of Eastern African immigrant women and 26.1% Australian-born women attempted a VBAC with 50.9% of Eastern African immigrants and 60.5% of Australian-born women being successful. After adjusting for maternal demographic characteristics and available clinical confounding factors, Eastern African immigrants were more likely to attempt (OR adj 1.94, 95% CI 1.57-2.47) but less likely to succeed (OR adj 0.54 95% CI 0.41-0.71) in having a VBAC. There are disparities in attempted and successful VBAC between Eastern African origin and Australian-born women. Unsuccessful VBAC attempt is more common among Eastern African immigrants, suggesting the need for improved strategies to select and support potential candidates for vaginal birth among these immigrants to enhance success and reduce potential complications associated with failed VBAC attempt. Crown Copyright © 2017. Published by Elsevier Ltd. All rights reserved.

  7. 22 CFR 40.93 - Aliens unlawfully present after previous immigration violation.

    Science.gov (United States)

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Aliens unlawfully present after previous... TO BOTH NONIMMIGRANTS AND IMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Aliens Previously Removed § 40.93 Aliens unlawfully present after previous immigration violation. An alien described...

  8. PROBLEMS AND POTENTIAL OF DEVELOPMENT OF THE INDUSTRIAL ENTERPRISES OF THE KNOWLEDGE-INTENSIVE BRANCHES

    Directory of Open Access Journals (Sweden)

    Mikhail Yakovlevich Veselovsky

    2016-01-01

    Full Text Available In the article the problems of enterprise development high-tech industries, analyzes the factors that complicate the processes of knowledge-intensive production management. It provided a number of problems that make it difficult to increase the economic efficiency of high-tech industry. To solve the above problems need to increase the investment program and the economic attractiveness of high-tech industries that is to be developed, modern management system, carried out the reform of the knowledge-based industry to provide high levels of efficiency of new organizational structures in the current economic conditions compared to the existing, outdated forms. The purpose / goal. The aim of this study is to analyze the causes that affect the development potential of knowledge-based industries and enterprises identify problems that impede improving the economic efficiency of the Russian high-tech industry. Purpose: To identify the problems that are most difficult to improve the economic efficiency of the Russian high-tech industry; consider the high-tech industry; examine the reasons for the reform of the knowledge-based industry; explore the level of innovation activity of organizations of high-tech industries. Methodology. The methodological and theoretical basis of the study are the works, monographs, research papers, studies of Soviet authors on the development of knowledge-intensive industries, materials of State Statistics. We used scientific methods of research, such as the comparative method of analysis, synthesis, analysis and synthesis. Results. Given the concept of the domestic high-tech complex (NEC, defined the environment in which businesses operate NEC. The features of these companies, where there is the presence of a strong innovation potential. The requirements for knowledge-intensive production as the backbone of a new stage of the development lifecycle. A number of problems hampering the development and transformation of enterprise

  9. Possible pulmonary Rhizopus oryzae infection in a previously healthy child after a near-drowning incident.

    Science.gov (United States)

    Gerlach, Magdalena M; Lippmann, Norman; Kobelt, Louise; Petzold-Quinque, Stefanie; Ritter, Lutz; Kiess, Wieland; Siekmeyer, Manuela

    2016-06-01

    This article reports on a previously healthy 17-month-old boy who developed pulmonary mucormycosis after a near-drowning incident in a goose pond. The patient survived without neurological sequelae and recovered, under treatment with amphotericin B, from the rare and often invasive fungal infection with Rhizopus spp., usually occurring in immunodeficient patients.

  10. Energy intensities: Prospects and potential

    International Nuclear Information System (INIS)

    Anon.

    1992-01-01

    In the previous chapter, the author described how rising activity levels and structural change are pushing toward higher energy use in many sectors and regions, especially in the developing countries. The extent to which more activity leads to greater energy use will depend on the energy intensity of end-use activities. In this chapter, the author presents an overview of the potential for intensity reductions in each sector over the next 10-20 years. It is not the author's intent to describe in detail the various technologies that could be employed to improve energy efficiency, which has been done by others (see, for example, Lovins ampersand Lovins, 1991; Goldembert et al., 1987). Rather, he discusses the key factors that will shape future energy intensities in different parts of the world, and gives a sense for the changes that could be attained if greater attention were given to accelerate efficiency improvement. The prospects for energy intensities, and the potential for reduction, vary among sectors and parts of the world. In the majority of cases, intensities are tending to decline as new equipment and facilities come into use and improvements are made on existing stocks. The effect of stock turnover will be especially strong in the developing countries, where stocks are growing at a rapid pace, and the Former East Bloc, where much of the existing industrial plant will eventually be retired and replaced with more modern facilities. While reductions in energy intensity are likely in most areas, there is a large divergence between the technical and economic potential for reducing energy intensities and the direction in which present trends are moving. In the next chapter, the author presents scenarios that illustrate where trends are pointing, and what could be achieved if improving energy efficiency were a focus of public policies. 53 refs., 4 figs., 2 tabs

  11. Development and growth potential of axillary buds in roses as affected by bud age.

    NARCIS (Netherlands)

    Marcelis-van Acker, C.A.M.

    1994-01-01

    The effect of axillary bud age on the development and potential for growth of the bud into a shoot was studied in roses. Age of the buds occupying a similar position on the plant varied from 'subtending leaf just unfolded' up to 1 year later. With increasing age of the axillary bud its dry mass,

  12. Evaluating Potential Human Health Risks Associated with the Development of Utility-Scale Solar Energy Facilities on Contaminated Sites

    Energy Technology Data Exchange (ETDEWEB)

    Cheng, J. -J. [Argonne National Lab. (ANL), Argonne, IL (United States); Chang, Y. -S. [Argonne National Lab. (ANL), Argonne, IL (United States); Hartmann, H. [Argonne National Lab. (ANL), Argonne, IL (United States); Wescott, K. [Argonne National Lab. (ANL), Argonne, IL (United States); Kygeris, C. [Indiana Univ. of Pennsylvania, PA (United States)

    2013-09-01

    This report presents a general methodology for obtaining preliminary estimates of the potential human health risks associated with developing a utility-scale solar energy facility on a contaminated site, based on potential exposures to contaminants in soils (including transport of those contaminants into the air).

  13. Study of the regional potential for the development of small hydroelectricity - Final report

    International Nuclear Information System (INIS)

    Ruillet, Mathieu; Buchet, Eric

    2005-01-01

    Whereas the potential of small hydroelectric plants in the eastern part of the PACA region, and more generally in the whole region appears to be promising to support energy supply safety, to reduce greenhouse gas emissions, and for local development, this study aimed at making an inventory of existing hydraulic plants (to be renewed or developed for a higher production), of existing weirs to be equipped, and of new sites to be possibly developed (non classified rives, irrigation canals, drinkable water networks). Another objective of this study was to propose a selection among the most promising sites or works. Moreover, the power for these existing or possible installations ranges from 100 kW to 10 MW. After a presentation of the adopted methodology, lists of sites are provided, as well as more detailed presentations of selected sites

  14. Detection of Lateralized Readiness Potential using Emotiv EPOC

    OpenAIRE

    Bártík, Radovan

    2013-01-01

    Emotiv EPOC is a low-cost consumer headset capable of acquiring a raw EEG signal. The thesis evaluates its usage for an acquisition of research event-related potentials. A controlled laboratory experiment was performed with an objective of isolating the Bereitschaftspotential (Readiness Potential) and other movement-related potentials and comparing the results with the results of the previous research. The possibility of measuring the potential with Emotiv EPOC was not confirmed, most probabl...

  15. An overview of water disinfection in developing countries and the potential for solar thermal water pasteurization

    Energy Technology Data Exchange (ETDEWEB)

    Burch, J.; Thomas, K.E.

    1998-01-01

    This study originated within the Solar Buildings Program at the U.S. Department of Energy. Its goal is to assess the potential for solar thermal water disinfection in developing countries. In order to assess solar thermal potential, the alternatives must be clearly understood and compared. The objectives of the study are to: (a) characterize the developing world disinfection needs and market; (b) identify competing technologies, both traditional and emerging; (c) analyze and characterize solar thermal pasteurization; (d) compare technologies on cost-effectiveness and appropriateness; and (e) identify research opportunities. Natural consequences of the study beyond these objectives include a broad knowledge of water disinfection problems and technologies, introduction of solar thermal pasteurization technologies to a broad audience, and general identification of disinfection opportunities for renewable technologies.

  16. Assessment of clean development mechanism potential of large-scale energy efficiency measures in heavy industries

    International Nuclear Information System (INIS)

    Hayashi, Daisuke; Krey, Matthias

    2007-01-01

    This paper assesses clean development mechanism (CDM) potential of large-scale energy efficiency measures in selected heavy industries (iron and steel, cement, aluminium, pulp and paper, and ammonia) taking India and Brazil as examples of CDM project host countries. We have chosen two criteria for identification of the CDM potential of each energy efficiency measure: (i) emission reductions volume (in CO 2 e) that can be expected from the measure and (ii) likelihood of the measure passing the additionality test of the CDM Executive Board (EB) when submitted as a proposed CDM project activity. The paper shows that the CDM potential of large-scale energy efficiency measures strongly depends on the project-specific and country-specific context. In particular, technologies for the iron and steel industry (coke dry quenching (CDQ), top pressure recovery turbine (TRT), and basic oxygen furnace (BOF) gas recovery), the aluminium industry (point feeder prebake (PFPB) smelter), and the pulp and paper industry (continuous digester technology) offer promising CDM potential

  17. Simple exercises to flatten your potential

    Energy Technology Data Exchange (ETDEWEB)

    Dong, Xi; Horn, Bart; Silverstein, Eva [Stanford Univ., Stanford, CA (United States). SLAC and Dept. of Physics; California Univ., Santa Barbara, CA (United States). Kavli Inst. for Theoretical Physics; Westphal, Alexander [Deutsches Elektronen-Synchrotron (DESY), Hamburg (Germany); Stanford Univ., Stanford, CA (United States). SLAC and Dept. of Physics

    2010-11-15

    We show how backreaction of the inflation potential energy on heavy scalar fields can flatten the inflationary potential, as the heavy fields adjust to their most energetically favorable configuration. This mechanism operates in previous UV-complete examples of axion monodromy inflation - flattening a would-be quadratic potential to one linear in the inflaton field - but occurs more generally, and we illustrate the effect with several examples. Special choices of compactification minimizing backreaction may realize chaotic inflation with a quadratic potential, but we argue that a flatter potential such as power-law inflation V({phi}){proportional_to} {phi}{sup p} with p<2 is a more generic option at sufficiently large values of {phi}. (orig.)

  18. Simple exercises to flatten your potential

    International Nuclear Information System (INIS)

    Dong, Xi; Horn, Bart; Silverstein, Eva; California Univ., Santa Barbara, CA; Westphal, Alexander; Stanford Univ., Stanford, CA

    2010-11-01

    We show how backreaction of the inflation potential energy on heavy scalar fields can flatten the inflationary potential, as the heavy fields adjust to their most energetically favorable configuration. This mechanism operates in previous UV-complete examples of axion monodromy inflation - flattening a would-be quadratic potential to one linear in the inflaton field - but occurs more generally, and we illustrate the effect with several examples. Special choices of compactification minimizing backreaction may realize chaotic inflation with a quadratic potential, but we argue that a flatter potential such as power-law inflation V(φ)∝ φ p with p<2 is a more generic option at sufficiently large values of φ. (orig.)

  19. Geoheritage and geotourism potential of the Strzelin Hills (Sudetic Foreland, SW Poland

    Directory of Open Access Journals (Sweden)

    Solarska Anna

    2010-01-01

    Full Text Available The aim of this paper is to present a state of knowledge about geotourism potential of the Strzelin Hills. Still there is no geotouristic infrastructure in the Strzelin Hills that could make available all their advantages for educational purposes. There are being carried out works on inventory and documentation to create a base for a development of geotourism. The geotouristic potential is described on the basis of previously studied and valorized objects of geological and geomorphological heritage. There were inventoried 38 objects of geoheritage. During valorization of 17 geosites and geomorphosites were selected 8 represented objects, which present 10 from the 15 thematic groups. There were briefly described 6 of them in this paper. .

  20. [Renal oncocytoma in the single kidney after previous surgery of renal carcinoma. Apropos of 2 cases].

    Science.gov (United States)

    Veneroni, L; Canclini, L; Berti, G L; Giola, V; Leidi, G L; Maccaroni, A; Raimoldi, A; Sironi, M; Assi, A; Bacchioni, A M

    1997-12-01

    Renal oncocytoma is a neoplasm which rarely occurs in patients with solitary kidney, the other being absent because of a previous nephrectomy performed for renal cancer. We present two case reports and a literature review. We have studied some important problems such as the histogenesis, the potential for malignancy, the diagnosis, the treatment and the follow up. The high incidence of coexistence of renal oncocytoma and renal cell carcinoma has important clinical implications. We would like to emphasize the importance of preoperatory FNAB, nephron sparing surgery and very careful follow up.

  1. Previous exercise training has a beneficial effect on renal and cardiovascular function in a model of diabetes.

    Directory of Open Access Journals (Sweden)

    Kleiton Augusto dos Santos Silva

    Full Text Available Exercise training (ET is an important intervention for chronic diseases such as diabetes mellitus (DM. However, it is not known whether previous exercise training intervention alters the physiological and medical complications of these diseases. We investigated the effects of previous ET on the progression of renal disease and cardiovascular autonomic control in rats with streptozotocin (STZ-induced DM. Male Wistar rats were divided into five groups. All groups were followed for 15 weeks. Trained control and trained diabetic rats underwent 10 weeks of exercise training, whereas previously trained diabetic rats underwent 14 weeks of exercise training. Renal function, proteinuria, renal sympathetic nerve activity (RSNA and the echocardiographic parameters autonomic modulation and baroreflex sensitivity (BRS were evaluated. In the previously trained group, the urinary albumin/creatinine ratio was reduced compared with the sedentary diabetic and trained diabetic groups (p<0.05. Additionally, RSNA was normalized in the trained diabetic and previously trained diabetic animals (p<0.05. The ejection fraction was increased in the previously trained diabetic animals compared with the diabetic and trained diabetic groups (p<0.05, and the myocardial performance index was improved in the previously trained diabetic group compared with the diabetic and trained diabetic groups (p<0.05. In addition, the previously trained rats had improved heart rate variability and BRS in the tachycardic response and bradycardic response in relation to the diabetic group (p<0.05. This study demonstrates that previous ET improves the functional damage that affects DM. Additionally, our findings suggest that the development of renal and cardiac dysfunction can be minimized by 4 weeks of ET before the induction of DM by STZ.

  2. Prevention of type 2 diabetes mellitus in women with previous gestational diabetes mellitus.

    Science.gov (United States)

    Moon, Joon Ho; Kwak, Soo Heon; Jang, Hak C

    2017-01-01

    Gestational diabetes mellitus (GDM), defined as any degree of glucose intolerance with onset or first recognition during pregnancy, is characterized by underlying maternal defects in the β-cell response to insulin during pregnancy. Women with a previous history of GDM have a greater than 7-fold higher risk of developing postpartum diabetes compared with women without GDM. Various risk factors for postpartum diabetes have been identified, including maternal age, glucose levels in pregnancy, family history of diabetes, pre-pregnancy and postpartum body mass index, dietary patterns, physical activity, and breastfeeding. Genetic studies revealed that GDM shares common genetic variants with type 2 diabetes. A number of lifestyle interventional trials that aimed to ameliorate modifiable risk factors, including diet, exercise, and breastfeeding, succeeded in reducing the incidence of postpartum diabetes, weight retention, and other obesity-related morbidities. The present review summarizes the findings of previous studies on the incidence and risk factors of postpartum diabetes and discusses recent lifestyle interventional trials that attempted to prevent postpartum diabetes.

  3. Energy Savings Potential and Research, Development, & Demonstration Opportunities for Commercial Building Appliances

    Energy Technology Data Exchange (ETDEWEB)

    Zogg, Robert [Navigant Consulting, Inc., Burlington, MA (United States); Goetzler, William [Navigant Consulting, Inc., Burlington, MA (United States); Ahlfeldt, Christopher [Navigant Consulting, Inc., Burlington, MA (United States); Hiraiwa, Hirokazu [Navigant Consulting, Inc., Burlington, MA (United States); Sathe, Amul [Navigant Consulting, Inc., Burlington, MA (United States); Sutherland, Timothy [Navigant Consulting, Inc., Burlington, MA (United States)

    2009-12-01

    This study characterizes and assesses the appliances used in commercial buildings. The primary objectives of this study were to document the energy consumed by commercial appliances and identify research, development and demonstration (RD&D) opportunities for efficiency improvements, excluding product categories such as HVAC, building lighting, refrigeration equipment, and distributed generation systems. The study included equipment descriptions, characteristics of the equipment’s market, national energy consumption, estimates of technical potential for energy-saving technologies, and recommendations for U.S. Department of Energy programs that can promote energy savings in commercial appliances.

  4. Methodology developed to make the Quebec indoor radon potential map

    Energy Technology Data Exchange (ETDEWEB)

    Drolet, Jean-Philippe, E-mail: jean-philippe.drolet@ete.inrs.ca [Institut national de la recherche scientifique, Eau Terre Environnement Research Centre (ETE-INRS), 490 de la Couronne, G1K 9A9 Quebec (Canada); Martel, Richard [Institut national de la recherche scientifique, Eau Terre Environnement Research Centre (ETE-INRS), 490 de la Couronne, G1K 9A9 Quebec (Canada); Poulin, Patrick [Institut national de santé publique du Québec (INSPQ), 945 avenue Wolfe, G1V 5B3 Quebec (Canada); Dessau, Jean-Claude [Agence de la santé et des services sociaux des Laurentides, 1000 rue Labelle, J7Z 5 N6 Saint-Jérome (Canada)

    2014-03-01

    This paper presents a relevant approach to predict the indoor radon potential based on the combination of the radiogeochemical data and the indoor radon measurements in the Quebec province territory (Canada). The Quebec ministry of health asked for such a map to identify the radon-prone areas to manage the risk for the population related to indoor radon exposure. Three radiogeochemical criteria including (1) equivalent uranium (eU) concentration from airborne surface gamma-ray surveys, (2) uranium concentration measurements in sediments, (3) bedrock and surficial geology were combined with 3082 basement radon concentration measurements to identify the radon-prone areas. It was shown that it is possible to determine thresholds for the three criteria that implied statistically significant different levels of radon potential using Kruskal–Wallis one way analyses of variance by ranks. The three discretized radiogeochemical datasets were combined into a total predicted radon potential that sampled 98% of the studied area. The combination process was also based on Kruskal–Wallis one way ANOVA. Four statistically significant different predicted radon potential levels were created: low, medium, high and very high. Respectively 10 and 13% of the dwellings exceed the Canadian radon guideline of 200 Bq/m{sup 3} in low and medium predicted radon potentials. These proportions rise up to 22 and 45% respectively for high and very high predicted radon potentials. This predictive map of indoor radon potential based on the radiogeochemical data was validated using a map of confirmed radon exposure in homes based on the basement radon measurements. It was shown that the map of predicted radon potential based on the radiogeochemical data was reliable to identify radon-prone areas even in zones where no indoor radon measurement exists. - Highlights: • 5 radiogeochemical datasets were used to map the geogenic indoor radon potential. • An indoor radon potential was determined for

  5. Deposition potential of polonium

    Energy Technology Data Exchange (ETDEWEB)

    Heal, H. G.

    1948-11-23

    The cathodic deposition potential for polonium in concentrations of 10{sup -13} normal and 8 x 10{sup -13} normal, the former being 100-fold smaller than the smallest concentrations previously studied, has been determined. The value is 0.64 volt on the hydrogen scale. Considering the various ways in which the graphs can reasonably be drawn, we consider the maximum possible error to be of the order of +- 0.03 volt. There is apparently no shift of deposition potential between concentrations of 10{sup -8} and 10{sup -13} normal, indicating that the Nernst equation is not applicable in these circumstances.

  6. 18 CFR 154.302 - Previously submitted material.

    Science.gov (United States)

    2010-04-01

    ... 18 Conservation of Power and Water Resources 1 2010-04-01 2010-04-01 false Previously submitted material. 154.302 Section 154.302 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY... concurrently with the rate change filing. There must be furnished to the Director, Office of Energy Market...

  7. Subsequent pregnancy outcome after previous foetal death

    NARCIS (Netherlands)

    Nijkamp, J. W.; Korteweg, F. J.; Holm, J. P.; Timmer, A.; Erwich, J. J. H. M.; van Pampus, M. G.

    Objective: A history of foetal death is a risk factor for complications and foetal death in subsequent pregnancies as most previous risk factors remain present and an underlying cause of death may recur. The purpose of this study was to evaluate subsequent pregnancy outcome after foetal death and to

  8. Development Potentials and Policy Options of Biomass in China

    Science.gov (United States)

    Shen, Lei; Liu, Litao; Yao, Zhijun; Liu, Gang; Lucas, Mario

    2010-10-01

    Biomass, one of the most important renewable energies, is playing and will continue to play an important role in the future energy structure of the world. This article aims to analyze the position and role, assess the resource availability, discuss the geographic distribution, market scale and industry development, and present the policy options of biomass in China. The resource availability and geographical distribution of biomass byproducts are assessed in terms of crop residues, manure, forest and wood biomass byproducts, municipal waste and wastewater. The position of biomass use for power generation is just next to hydropower among types of renewable energy in China. The potential quantity of all biomass byproducts energy in 2004 is 3511 Mtce (Mtce is the abbreviation of million tons of coal equivalents and 1 Mtce is equal to106 tce.), while the acquirable quantity is 460 Mtce. Biomass energy plays a critical role in rural regions of China. The geographical distribution and quantity of biomass byproducts resources depends mainly on the relationship between ecological zones and climate conditions. Our estimation shows that the total quantity of crop residues, manure, forest and wood biomass byproducts, municipal waste and wastewater resources are 728, 3926, 2175, 155 and 48240 Mt (million tons), respectively. Crop residues come mainly from the provinces of Henan, Shandong, Heilongjiang, Jilin and Sichuan. All manure is mainly located in the provinces of Henan, Shandong, Sichuan, Hebei and Hunan. Forest and wood biomass byproducts are mainly produced in the provinces or autonomous regions of Tibet, Sichuan, Yunnan, Heilongjiang and Inner Mongolia, while most of municipal waste mainly comes from Guangdong, Shandong, Heilongjiang, Hubei and Jiangsu. Most of wastewater is largely discharged from advanced provinces like Guangdong, Jiangsu, Zhejiang, Shandong and Henan. Biomass byproducts’ energy distribution also varies from province to province in China. Based on

  9. A Parametric Computational Model of the Action Potential of Pacemaker Cells.

    Science.gov (United States)

    Ai, Weiwei; Patel, Nitish D; Roop, Partha S; Malik, Avinash; Andalam, Sidharta; Yip, Eugene; Allen, Nathan; Trew, Mark L

    2018-01-01

    A flexible, efficient, and verifiable pacemaker cell model is essential to the design of real-time virtual hearts that can be used for closed-loop validation of cardiac devices. A new parametric model of pacemaker action potential is developed to address this need. The action potential phases are modeled using hybrid automaton with one piecewise-linear continuous variable. The model can capture rate-dependent dynamics, such as action potential duration restitution, conduction velocity restitution, and overdrive suppression by incorporating nonlinear update functions. Simulated dynamics of the model compared well with previous models and clinical data. The results show that the parametric model can reproduce the electrophysiological dynamics of a variety of pacemaker cells, such as sinoatrial node, atrioventricular node, and the His-Purkinje system, under varying cardiac conditions. This is an important contribution toward closed-loop validation of cardiac devices using real-time heart models.

  10. Being prepared on time: On the importance of the previous foreperiod on current preparation, as reflected in speed force and preparation-related brain potentials.

    NARCIS (Netherlands)

    Van der Lubbe, R.H.J.; Los, S.A.; Jaskowski, P.; Verleger, R.

    2004-01-01

    How do participants adapt to temporal variation of preparatory foreperiods? For reaction times, specific sequential effects have been observed. Responses become slower when the foreperiod is shorter on the current than on the previous trial. If this effect is due to changes in motor activation, it

  11. Being prepared on time: on the importance of the previous foreperiod to current preparation, as reflected in speed, force and preparation-related brain potentials

    NARCIS (Netherlands)

    van der Lubbe, Robert Henricus Johannes; Los, Sander A.; Jaśkowski, Piotr; Verleger, Rolf

    2004-01-01

    How do participants adapt to temporal variation of preparatory foreperiods? For reaction times, specific sequential effects have been observed. Responses become slower when the foreperiod is shorter on the current than on the previous trial. If this effect is due to changes in motor activation, it

  12. Career development and personal success profile of students - followers and students - potential future leaders: The case of RIT Croatia

    Directory of Open Access Journals (Sweden)

    Jasminka Samardžija

    2017-01-01

    Full Text Available This study examines the differences among students in terms of self-reported leadership characteristics. It was conducted among all three programs and four generations of undergraduates at RIT Croatia. The goal of this study is to determine the differences among students who report being more and less leadership prone (Potential Future Leaders and Followers, respectively with regard to demographic characteristics, reported self reliance socialization pattern, college level and program choice, career focus attainment and development, and reported attitudes regarding the importance of specific personality traits in leadership, the importance of specific career development factors and success indicators. Research showed that generation and college program are not related to student reported leadership proneness, suggesting that college education’s impact on leadership traits is not significant. Only one socio-demographic factor considered was significantly different between clusters; namely, the respondents who had moved once were significantly more represented in the Potential Future Leaders cluster, suggesting that study-abroad programs might play a role in leadership development. In terms of ranking career development factors, success indicators, the importance of emotional stability and openness to experience as a specific leadership trait, Potential Future Leaders reported higher scores in comparison with Followers cluster, potentially resulting from their forwardlooking, goal-oriented attitude.

  13. [Meningitis and white matter lesions due to Streptococcus mitis in a previously healthy child].

    Science.gov (United States)

    Yiş, Reyhan; Yüksel, Ciğdem Nükhet; Derundere, Umit; Yiş, Uluç

    2011-10-01

    Streptococcus mitis, an important member of viridans streptococci, is found in the normal flora of the oropharynx, gastrointestinal tract, female genital tract and skin. Although it is of low pathogenicity and virulence, it may cause serious infections in immunocompromised patients. Meningitis caused by S.mitis has been described in patients with previous spinal anesthesia, neurosurgical procedure, malignancy, bacterial endocarditis with neurological complications and alcoholics, but it is rare in patients who are previously healthy. In this report, a rare case of meningoencephalitis caused by S.mitis developed in a previously healthy child has been presented. A previously healthy eight-year-old girl who presented with fever, altered state of consciousness, and headache was hospitalized in intensive care unit with the diagnosis of meningitis. Past history revealed that she was treated with amoxicillin-clavulanate for acute sinusitis ten days before her admission. Whole blood count revealed the followings: hemoglobin 13 g/dl, white blood cell count 18.6 x 109/L (90% neutrophils), platelet count 200 x 109/L and 150 leucocytes were detected on cerebrospinal fluid (CSF) examination. Protein and glucose levels of CSF were 80 mg/dl and 40 mg/dl (concomitant blood glucose 100 mg/dl), respectively. Brain magnetic resonance imaging (MRI) revealed widespread white matter lesions, and alpha-hemolytic streptococci were grown in CSF culture. The isolate was identified as S.mitis with conventional methods, and also confirmed by VITEK2 (bioMerieux, France) and API 20 STREP (bioMerieux, France) systems. Isolate was found susceptible to penicillin, erythromycin, clindamycin, tetracycline, cefotaxime, vancomycin and chloramphenicol. Regarding the etiology, echocardiography revealed no vegetation nor valve pathology, and peripheral blood smear showed no abnormality. Immunoglobulin and complement levels were within normal limits. Ongoing inflammation in maxillary sinuses detected in

  14. POTENTIAL FOR DEVELOPMENT OF INTEGRATED MULTI-TROPHIC AQUACULTURE (IMTA IN THE ADRIATIC SEA

    Directory of Open Access Journals (Sweden)

    Danijel Kanski

    2012-12-01

    Full Text Available Over recent years, scientific interest for investigating ecological, economical and social effects of Integrated Multi-trophic Aquaculture (IMTA has increased worldwide. Its development in the Mediterranean, including the Adriatic Sea, is still in the early stages. The main obstacle preventing IMTA to be commercially adopted is the lack of scientific information on choosing compatible species, knowing the carrying capacity of a production area and interactions between species feeding at different trophic levels, as well as its socio–economic impacts. Current experience in the area is based on smaller experimental studies of local importance but they generally give a good insight into potential of IMTA and its interactions with the environment. The aim of this paper was to overview current literature and experiences worldwide and to review the potential for adopting IMTA principles in the Adriatic Sea.

  15. Is Cup Positioning Challenged in Hips Previously Treated With Periacetabular Osteotomy?

    DEFF Research Database (Denmark)

    Hartig-Andreasen, Charlotte; Stilling, Maiken; Søballe, Kjeld

    2014-01-01

    After periacetabular osteotomy (PAO), some patients develop osteoarthritis with need of a total hip arthroplasty (THA). We evaluated the outcome of THA following PAO and explored factors associated with inferior cup position and increased polyethylene wear. Follow-up were performed 4 to 10years...... after THA in 34 patients (38 hips) with previous PAO. Computer analysis evaluated cup position and wear rates. No patient had dislocations or revision surgery. Median scores were: Harris hip 96, Oxford hip 38 and WOMAC 78. Mean cup anteversion and abduction angles were 22(o) (range 7°-43°) and 45......° (range 28°-65°). Outliers of cup abduction were associated with persisting dysplasia (CE...

  16. Left ventricular asynergy score as an indicator of previous myocardial infarction

    International Nuclear Information System (INIS)

    Backman, C.; Jacobsson, K.A.; Linderholm, H.; Osterman, G.

    1986-01-01

    Sixty-eight patients with coronary heart disease (CHD) i.e. a hisotry of angina of effort and/or previous 'possible infarction' were examined inter alia with ECG and cinecardioangiography. A system of scoring was designed which allowed a semiquantitative estimate of the left ventricular asynergy from cinecardioangiography - the left ventricular motion score (LVMS). The LVMS was associated with the presence of a previous myocardial infarction (MI), as indicated by the history and ECG findings. The ECG changes specific for a previous MI were associated with high LVMS values and unspecific or absent ECG changes with low LVMS values. Decision thresholds for ECG changes and asynergy in diagnosing a previous MI were evaluated by means of a ROC analysis. The accuracy of ECG in detecting a previous MI was slightly higher when asynergy indicated a 'true MI' than when autopsy result did so in a comparable group. Therefore the accuracy of asynergy (LVMS ≥ 1) in detecting a previous MI or myocardial fibrosis in patients with CHD should be at least comparable with that of autopsy (scar > 1 cm). (orig.)

  17. High-temperature axion potential

    International Nuclear Information System (INIS)

    Dowrick, N.J.; McDougall, N.A.

    1989-01-01

    We investigate the possibility of new terms in the high-temperature axion potential arising from the dynamical nature of the axion field and from higher-order corrections to the θ dependence in the free energy of the quark-gluon plasma. We find that the dynamical nature of the axion field does not affect the potential but that the higher-order effects lead to new terms in the potential which are larger than the term previously considered. However, neither the magnitude nor the sign of the potential can be calculated by a perturbative expansion of the free energy since the coupling is too large. We show that a change in the magnitude of the potential does not significantly affect the bound on the axion decay constant but that the sign of the potential is of crucial importance. By investigating the formal properties of the functional integral within the instanton dilute-gas approximation, we find that the sign of the potential does not change and that the minimum remains at θ=0. We conclude that the standard calculation of the axion energy today is not significantly modified by this investigation

  18. Polychlorinated biphenyl exposure, diabetes and endogenous hormones: a cross-sectional study in men previously employed at a capacitor manufacturing plant.

    Science.gov (United States)

    Persky, Victoria; Piorkowski, Julie; Turyk, Mary; Freels, Sally; Chatterton, Robert; Dimos, John; Bradlow, H Leon; Chary, Lin Kaatz; Burse, Virlyn; Unterman, Terry; Sepkovic, Daniel W; McCann, Kenneth

    2012-08-29

    Studies have shown associations of diabetes and endogenous hormones with exposure to a wide variety of organochlorines. We have previously reported positive associations of polychlorinated biphenyls (PCBs) and inverse associations of selected steroid hormones with diabetes in postmenopausal women previously employed in a capacitor manufacturing plant. This paper examines associations of PCBs with diabetes and endogenous hormones in 63 men previously employed at the same plant who in 1996 underwent surveys of their exposure and medical history and collection of bloods and urine for measurements of PCBs, lipids, liver function, hematologic markers and endogenous hormones. PCB exposure was positively associated with diabetes and age and inversely associated with thyroid stimulating hormone and triiodothyronine-uptake. History of diabetes was significantly related to total PCBs and all PCB functional groupings, but not to quarters worked and job score, after control for potential confounders. None of the exposures were related to insulin resistance (HOMA-IR) in non-diabetic men. Associations of PCBs with specific endogenous hormones differ in some respects from previous findings in postmenopausal women employed at the capacitor plant. Results from this study, however, do confirm previous reports relating PCB exposure to diabetes and suggest that these associations are not mediated by measured endogenous hormones.

  19. Congenital costo-vertebral fibrous band and congenital kyphoscoliosis: a previously unreported combination.

    Science.gov (United States)

    Eid, Tony; Ghostine, Bachir; Kreichaty, Gaby; Daher, Paul; Ghanem, Ismat

    2013-05-01

    Congenital kyphoscoliosis (CKS) results from abnormal vertebral chondrification. Congenital fibrous bands occur in several locations with variable impact on vertebral development. We report a previously unreported case of a female infant with CKS presenting with an L2 hypoplastic vertebra and a costo-vertebral fibrous band extending to the skin in the form of a dimple. We also describe the therapeutic approach, consisting of surgical excision of the fibrous band and postoperative fulltime bracing, with a 7-year follow-up. We recommend a high index of suspicion in any unusual presentation of CKS and insist on case by case management in such cases.

  20. A review of Curtiss-Wright rotary engine developments with respect to general aviation potential

    Science.gov (United States)

    Jones, C.

    1979-01-01

    Aviation related rotary (Wankel-type) engine tests, possible growth directions and relevant developments at Curtiss-Wright have been reviewed. Automotive rotary engines including stratified charge are described and flight test results of rotary aircraft engines are presented. The current 300 HP engine prototype shows basic durability and competitive performance potential. Recent parallel developments have separately confirmed the geometric advantages of the rotary engine for direct injected unthrottled stratified charge. Specific fuel consumption equal to or better than pre- or swirl-chamber diesels, low emission and multi-fuel capability have been shown by rig tests of similar rotary engine.

  1. Advanced Self-Potential Inversion. Development and Use for Investigating Natural Recharge Processes at the ORNL IFC

    Energy Technology Data Exchange (ETDEWEB)

    Revil, Andre [Colorado School of Mines, Golden, CO (United States)

    2013-01-15

    Understanding the influence of coupled biological, chemical, and hydrological processes on subsurface contaminant behavior at multiple scales is a prerequisite for developing effective remedial approaches, whether they are active remediation or natural attenuation strategies. To develop this understanding, methods are needed that can measure critical components of the natural system in real time. The self-potential method corresponds to the passive measurement of the distribution of the electrical potential at the surface of the Earth or in boreholes. This method is very complemetary to other geophysical methods like DC resistivity and induced polarization. In this report, we summarize of research efforts to advance the theory of low-frequency geoelectrical methods and their applications to the contaminant plumes in the vicinity of the former S-3 settling basins at Oak Ridge, TN.

  2. Beyond cockpit-ism : Four insights to enhance the transformative potential of the sustainable development goals

    NARCIS (Netherlands)

    Hajer, Maarten|info:eu-repo/dai/nl/074798626; Nilsson, Måns; Raworth, Kate; Berkhout, Frans; de Boer, Yvo; Rockström, Johan; Ludwig, Kathrin; Kok, Marcel

    2015-01-01

    The Sustainable Development Goals (SDG) have the potential to become a powerful political vision that can support the urgently needed global transition to a shared and lasting prosperity. In December 2014, the United Nations (UN) Secretary General published his report on the SDGs. However, the final

  3. Potential effects of energy development on environmental resources of the Williston Basin in Montana, North Dakota, and South Dakota

    Science.gov (United States)

    Post van der Burg, Max; Vining, Kevin C.; Frankforter, Jill D.

    2017-09-28

    The Williston Basin, which includes parts of Montana, North Dakota, and South Dakota in the United States, has been a leading domestic oil and gas producing area. To better understand the potential effects of energy development on environmental resources in the Williston Basin, the U.S. Geological Survey, in cooperation with the Bureau of Land Management, and in support of the needs identified by the Bakken Federal Executive Group (consisting of representatives from 13 Federal agencies and Tribal groups), began work to synthesize existing information on science topics to support management decisions related to energy development. This report is divided into four chapters (A–D). Chapter A provides an executive summary of the report and principal findings from chapters B–D. Chapter B provides a brief compilation of information regarding the history of energy development, physiography, climate, land use, demographics, and related studies in the Williston Basin. Chapter C synthesizes current information about water resources, identifies potential effects from energy development, and summarizes water resources research and information needs in the Williston Basin. Chapter D summarizes information about ecosystems, species of conservation concern, and potential effects to those species from energy development in the Williston Basin.

  4. Potential brain imaging using near field radiomety

    International Nuclear Information System (INIS)

    Oikonomou, A; Karanasiou, I S; Uzunoglu, N K

    2009-01-01

    During the past decades there has been a tremendous increase throughout the scientific community for developing methods of understanding human brain functionality, as diagnosis and treatment of diseases and malfunctions could be effectively developed through understanding of how the brain works. In parallel, research effort is driven on minimizing drawbacks of existing imaging techniques including potential risks from radiation and invasive attributes of the imaging methodologies. Towards that direction, we are proposing a near filed radiometry imaging system for intracranial applications. The methodology is based on the fact that human tissues emit chaotic thermal type radiation at temperatures above the absolute zero. Using a phase shifted antenna array system, resolution, detection depth and sensitivity are increased. Several different setups are theoretically investigated and compared, so as to make the proposed system useful for clinical applications. Combining previous research as well as new findings, the possibility of using the proposed system as a complementary method for brain imaging is discussed in the present paper.

  5. Development of a Strontium Magneto-Optical Trap for Probing Casimir-Polder Potentials

    Science.gov (United States)

    Martin, Paul J.

    In recent years, cold atoms have been the centerpiece of many remarkably sensitive measurements, and much effort has been made to devise miniaturized quantum sensors and quantum information processing devices. At small distances, however, mechanical effects of the quantum vacuum begin to significantly impact the behavior of the cold-atom systems. A better understanding of how surface composition and geometry affect Casimir and Casimir-Polder potentials would benefit future engineering of small-scale devices. Unfortunately, theoretical solutions are limited and the number of experimental techniques that can accurately detect such short-range forces is relatively small. We believe the exemplary properties of atomic strontium--which have enabled unprecedented frequency metrology in optical lattice clocks--make it an ideal candidate for probing slight spectroscopic perturbations caused by vacuum fluctuations. To that end, we have constructed a magneto-optical trap for strontium to enable future study of atom-surface potentials, and the apparatus and proposed detection scheme are discussed herein. Of special note is a passively stable external-cavity diode laser we developed that is both affordable and competitive with high-end commercial options.

  6. Expert Evaluation of Potential Points of Economic Growth in the Regions of Russia and the Conditions of their Development

    Directory of Open Access Journals (Sweden)

    A. V. Tihonov

    2017-01-01

    Full Text Available Purpose: the main purpose of this article is to identify « growth points» of economic growth in the regions, determine their type, and assess the conditions for their development. Methods: the main feature of this study is to obtain an expert assessment of the qualitative aspects of regional development. The main source of empirical data was an online survey conducted by the authors in 2016. Results: the study identified potential «growth points» in five regions of the Russian Federation and determined their nature according to the idea of modernizing the socio-economic environment. The selected points allow to develop the potential of the region horizontally. However, there are certain problems that hinder this development and they have been identified. Conclusions and Relevance: at the moment, the identified «growth points» can not be classified as information or intellectual, but in all regions there is the possibility of activating such industries. The «growth points» allocated by experts are still potential, because their technical, technological and innovative components have medium level of development. «Growth points» in the Republic of Sakha and the Nizhny Novgorod region have a greater modernization activity. Such expertise can be used by local authorities to adjust development vectors and strategies. It can also be an element of monitoring the socioeconomic development of regions. 

  7. The potential for satellite and marginal field developments on the Norwegian continental shelf

    International Nuclear Information System (INIS)

    Raustein, O.; Abrahamsen, L.E.; Einang, G.

    1994-01-01

    Norway is faced with decreasing field sizes in hostile waters. On the other hand, approximately 620 billion 1993-NOK have been invested in field installations and transport systems. These installations will have significant available processing and transport capacity in the future, and thus represent a valuable infrastructure. This paper describes the resource situation and the installed infrastructure on the Norwegian Continental Shelf. Then the potential of still maintaining a high activity level in field developments is outlined

  8. Potentials for development of spa tourism in region of Cer Mountain: Western Serbia

    Directory of Open Access Journals (Sweden)

    Grčić Mirko

    2006-01-01

    Full Text Available Because of their particularities, thermal and mineral springs at the foothill of Cer Mountain deserve special analysis. This is the reason we wrote this article, aiming to take reader's attention to the touristic potentials of the spa zone of Cer Mountain and possibilities for its perspective development. From the medical and excursion-recreational tourism point of view, there is a possibility for combining the spa tourism with the complementary values of Cer Mountain.

  9. US enrichment safeguards program development activities with potential International Atomic Energy Agency safeguards applications. Part 1. Executive summaries

    International Nuclear Information System (INIS)

    Swindle, D.W. Jr.

    1984-07-01

    The most recent progress, results, and plans for future work on the US Enrichment Safeguards Program's principal development activities are summarized. Nineteen development activities are reported that have potential International Atomic Energy Agency (IAEA) safeguards applications. Part 1 presents Executive Summaries for these, each of which includes information on (1) the purpose and scope of the development activity; (2) the potential IAEA safeguards application and/or use if adopted; (3) significant development work, results, and/or conclusions to date; and where appropriate (4) future activities and plans for continued work. Development activities cover: measurement technology for limited-frequency-unannounced-access stategy inspections; integrated data acquisition system; enrichment-monitoring system; load-cell-based weighing system for UF 6 cylinder mass verifications; vapor phase versus liquid phase sampling of UF 6 cylinders; tamper-safing hardware and systems; an alternative approach to IAEA nuclear material balance verifications resulting from intermittent inspections; UF 6 sample bottle enrichment analyzer; crated waste assay monitor; and compact 252 Cf shuffler for UF 6 measurements

  10. Implementation of success factors in new product development: The missing link

    DEFF Research Database (Denmark)

    Jensen, Bjarne; Harmsen, Hanne

    2001-01-01

    This paper addresses companies' lack of implementation of success factors in new product development. Drawing on theory in the competence perspective and an exploratory empirical study, the paper points to two major areas that have not been covered by previous studies on new product development s...... success factors. The two areas are knowledge and skills of individual employees, values and norms and it is suggested that increased understanding of these two areas hold potential in making identified success factors more accessible to companies.......This paper addresses companies' lack of implementation of success factors in new product development. Drawing on theory in the competence perspective and an exploratory empirical study, the paper points to two major areas that have not been covered by previous studies on new product development...

  11. On transparent potentials: a Born approximation study

    International Nuclear Information System (INIS)

    Coudray, C.

    1980-01-01

    In the frame of the scattering inverse problem at fixed energy, a class of potentials transparent in Born approximation is obtained. All these potentials are spherically symmetric and are oscillating functions of the reduced radial variable. Amongst them, the Born approximation of the transparent potential of the Newton-Sabatier method is found. In the same class, quasi-transparent potentials are exhibited. Very general features of potentials transparent in Born approximation are then stated. And bounds are given for the exact scattering amplitudes corresponding to most of the potentials previously exhibited. These bounds, obtained at fixed energy, and for large values of the angular momentum, are found to be independent on the energy

  12. An Exploration of the Validity and Potential of Adult Ego Development for Enhancing Understandings of School Leadership

    Science.gov (United States)

    James, Chris; James, Jane; Potter, Ian

    2017-01-01

    An adult ego development (AED) perspective accepts that the way adults interpret and interact in the social world can change during their life-span. This article seeks to analyse the validity and potential of AED for enhancing understandings of educational leadership practice and development. We analysed the AED literature and interviewed 16…

  13. Pattern visual evoked potentials in malingering.

    Science.gov (United States)

    Nakamura, A; Akio, T; Matsuda, E; Wakami, Y

    2001-03-01

    We previously developed a new method for estimating objective visual acuity by means of pattern visual evoked potentials (PVEP). In this study, this method was applied to the diagnosis of malingering. Six patients ranging in age from 40 to 54 years (mean 47 years) with suspected malingering were evaluated by means of the visual evoked potential test, optokinetic nystagmus (OKN) inhibition test, and the visual field test. In the PVEP study, the stimulus consisted of black and white checkerboards (39', 26', 15', and 9') with a visual angle of 8 degrees, contrast level of 15%, and a frequency of 0.7 Hz. One hundred PVEP responses were averaged per session. Routine ophthalmic examinations were normal in all patients. Five patients had a tubularly constricted visual field, and the remaining patient had a normal visual field. The objective visual acuities of the six patients estimated from PVEP were better than their subjective visual acuities estimated with Landolt rings. Among a variety of psychophysical and electrophysiologic ancillary tests, we consider our PVEP method a useful method for objectively determining visual acuity in a patient with signs of ocular malingering.

  14. Heparan Sulfate: A Potential Candidate for the Development of Biomimetic Immunomodulatory Membranes

    Directory of Open Access Journals (Sweden)

    Bruna Corradetti

    2017-09-01

    Full Text Available Clinical trials have demonstrated that heparan sulfate (HS could be used as a therapeutic agent for the treatment of inflammatory diseases. Its anti-inflammatory effect makes it suitable for the development of biomimetic innovative strategies aiming at modulating stem cells behavior toward a pro-regenerative phenotype in case of injury or inflammation. Here, we propose collagen type I meshes fabricated by solvent casting and further crosslinked with HS (HS-Col to create a biomimetic environment resembling the extracellular matrix of soft tissue. HS-Col meshes were tested for their capability to provide physical support to stem cells’ growth, maintain their phenotypes and immunosuppressive potential following inflammation. HS-Col effect on stem cells was investigated in standard conditions as well as in an inflammatory environment recapitulated in vitro through a mix of pro-inflammatory cytokines (tumor necrosis factor-α and interferon-gamma; 20 ng/ml. A significant increase in the production of molecules associated with immunosuppression was demonstrated in response to the material and when cells were grown in presence of pro-inflammatory stimuli, compared to bare collagen membranes (Col, leading to a greater inhibitory potential when mesenchymal stem cells were exposed to stimulated peripheral blood mononuclear cells. Our data suggest that the presence of HS is able to activate the molecular machinery responsible for the release of anti-inflammatory cytokines, potentially leading to a faster resolution of inflammation.

  15. Cumulative environmental risk in substance abusing women: early intervention, parenting stress, child abuse potential and child development.

    Science.gov (United States)

    Nair, Prasanna; Schuler, Maureen E; Black, Maureen M; Kettinger, Laurie; Harrington, Donna

    2003-09-01

    To assess the relationship between cumulative environmental risks and early intervention, parenting attitudes, potential for child abuse and child development in substance abusing mothers. We studied 161 substance-abusing women, from a randomized longitudinal study of a home based early intervention, who had custody of their children through 18 months. The intervention group received weekly home visits in the first 6 months and biweekly visits from 6 to 18 months. Parenting stress and child abuse potential were assessed at 6 and 18 months postpartum. Children's mental and motor development (Bayley MDI and PDI) and language development (REEL) were assessed at 6, 12, and 18 months postpartum. Ten maternal risk factors were assessed: maternal depression, domestic violence, nondomestic violence, family size, incarceration, no significant other in home, negative life events, psychiatric problems, homelessness, and severity of drug use. Level of risk was recoded into four categories (2 or less, 3, 4, and 5 or more), which had adequate cell sizes for repeated measures analysis. Repeated measures analyses were run to examine how level of risk and group (intervention or control) were related to parenting stress, child abuse potential, and children's mental, motor and language development over time. Parenting stress and child abuse potential were higher for women with five risks or more compared with women who had four or fewer risks; children's mental, motor, and language development were not related to level of risk. Children in the intervention group had significantly higher scores on the PDI at 6 and 18 months (107.4 vs. 103.6 and 101.1 vs. 97.2) and had marginally better scores on the MDI at 6 and 12 months (107.7 vs. 104.2 and 103.6 vs. 100.1), compared to the control group. Compared to drug-abusing women with fewer than five risks, women with five or more risks found parenting more stressful and indicated greater inclination towards abusive and neglectful behavior

  16. DIFFERENT ARGUMENTS FOR AND AGAINST THE ROLE AND IMPACT OF FOREIGN INVESTMENT ON THE DEVELOPMENT POTENTIALS OF DEVELOPING COUNTRIES: AN OVERVIEW

    Directory of Open Access Journals (Sweden)

    HÜSEYİN ŞEN

    2013-05-01

    Full Text Available This study explores different arguments for and against the role of foreign investment on the development potentials of developing countries. Generally, foreign investment comes to host countries through transnational corporatios (TNCs. These corporations are global profit-seeking organisations, investing in more than one country and supplying financial capital, management, technology and marketing enterprise. The arguments for and against the role and impact of foreign investment focus mainly on the following areas: economic growth, technology transfer, balance of payments, export performance, employment, environment, and transfer pricing as well as socio-cultural aspects of TNCs. The study concludes that with the appropriate government policies, such as unbiased trade regime, market reform and cooperation, developing countries could provide more benefits from foreign investment.

  17. The Importance of Business Model Factors for Cloud Computing Adoption: Role of Previous Experiences

    Directory of Open Access Journals (Sweden)

    Bogataj Habjan Kristina

    2017-08-01

    Full Text Available Background and Purpose: Bringing several opportunities for more effective and efficient IT governance and service exploitation, cloud computing is expected to impact the European and global economies significantly. Market data show that despite many advantages and promised benefits the adoption of cloud computing is not as fast and widespread as foreseen. This situation shows the need for further exploration of the potentials of cloud computing and its implementation on the market. The purpose of this research was to identify individual business model factors with the highest impact on cloud computing adoption. In addition, the aim was to identify the differences in opinion regarding the importance of business model factors on cloud computing adoption according to companies’ previous experiences with cloud computing services.

  18. Development of Creative Potential of Cinema Tourism

    Science.gov (United States)

    Dzhandzhugazova, Elena A.; Ilinaa, Elena L.; Latkin, Aleksander N.; Koshelevava, Anna I.

    2016-01-01

    The relevance of the problem indicated in the article is caused by the fact that under current conditions it is necessary to offer high-quality and demanded tourist products, formed at the combination of various industries on the basis of wide application of creative potential of different industries, including tourism and cinema, a harmonious…

  19. Classification for longevity potential: the use of novel biomarkers

    Directory of Open Access Journals (Sweden)

    Marian Beekman

    2016-10-01

    Full Text Available Background: In older people chronological age may not be the best predictor of residual lifespan and mortality, because with age the heterogeneity in health is increasing. Biomarkers for biological age and residual lifespan are being developed to predict disease and mortality better at an individual level than chronological age. In the current paper we aim to classify a group of older people into those with longevity potential or controls.Methods: In the Leiden Longevity Study participated 1671 offspring of nonagenarian siblings, as the group with longevity potential, and 744 similarly aged controls. Using known risk factors for cardiovascular disease, previously reported markers for human longevity and other physiological measures as predictors, classification models for longevity potential were constructed with multiple logistic regression of the offspring-control status.Results: The Framingham Risk Score is predictive for longevity potential (AUC = 64.7. Physiological parameters involved in immune responses and glucose, lipid and energy metabolism further improve the prediction performance for longevity potential (AUCmale = 71.4, AUCfemale = 68.7.Conclusion: Using the Framingham Risk Score, the classification of older people in groups with longevity potential and controls is moderate, but can be improved to a reasonably good classification in combination with markers of immune response, glucose, lipid and energy metabolism. We show that individual classification of older people for longevity potential may be feasible using biomarkers from a wide variety of different biological processes.

  20. Total knee arthroplasty in patients with a previous patellectomy.

    Science.gov (United States)

    Maslow, Jed; Zuckerman, Joseph D; Immerman, Igor

    2013-01-01

    Post-patellectomy patients represent a specific subgroup of patients that may develop arthritis and persistent knee pain and potentially require treatment with total knee arthroplasty. This article reviews the treatment and functional outcomes following total knee arthroplasty in patients with prior patellectomy. A case report is presented as an example of the clinical management of a post-patellectomy patient with significant knee pain and disability treated with total knee arthroplasty. Emphasis will be placed in decision- making, specifically with the use of a posterior stabilized implant. In addition, postoperative strengthening of the quadriceps is essential to compensate for the lack of the patella and increase the success of total knee arthroplasty in this subgroup of patients.

  1. Should previous mammograms be digitised in the transition to digital mammography?

    International Nuclear Information System (INIS)

    Taylor-Phillips, S.; Gale, A.G.; Wallis, M.G.

    2009-01-01

    Breast screening specificity is improved if previous mammograms are available, which presents a challenge when converting to digital mammography. Two display options were investigated: mounting previous film mammograms on a multiviewer adjacent to the workstation, or digitising them for soft copy display. Eight qualified screen readers were videotaped undertaking routine screen reading for two 45-min sessions in each scenario. Analysis of gross eye and head movements showed that when digitised, previous mammograms were examined a greater number of times per case (p=0.03), due to a combination of being used in 19% more cases (p=0.04) and where used, looked at a greater number of times (28% increase, p=0.04). Digitising previous mammograms reduced both the average time taken per case by 18% (p=0.04) and the participants' perceptions of workload (p < 0.05). Digitising previous analogue mammograms may be advantageous, in particular in increasing their level of use. (orig.)

  2. The Tourist Potential and Sustainable Development – New Trends and Opportunities for Galati Located in Romania´S South-East Development Region

    Directory of Open Access Journals (Sweden)

    Ionica SOARE

    2017-12-01

    Full Text Available Galati, danubian harbor city from the South Eastern Development Area of Romania, in not found on the UNESCO patrimony list of tourist attractions but disposes of a huge tourist potential that can be capitalized. Along with the neighbouring danubian harbour city – Braila – it forms one of the unique urban groups in the country through its geographical position, number of inhabitants, history and culture and both towns are regarded as poles of urban development. For the time being, the lack of the abilities/ competences of comprehensible formulation of efficient capitalization of the tourist potential generated by the natural environment and cultural inheritance of Galati Town, through the cosmopolitan character of great Danube harbour and fair (with agricultural products- cereals, honey and wax and so on close to the Black Sea and everything that belongs to it restrains and detains the manifestation of its tourist identity and competitiveness and identity. Thus, the identification of novelty elements as opportunities on which the paper focuses and which can ensure the promotion and development of the real needs of the town through tourism comes from an integrated correlation of the aspects that belong to the whole potential of Galatzi area, from the impact arising out of the geographical, geopolitical, political and economical position of Galati,the level of implication various actors can have, the policies and contemporary local / regional / European strategies, etc. The development of ideas in an integrated and partial way can constitute even the support of a proeminent consulting base (work groups formed of spokesmen with high qualification from academic, economic and business fields and who know the real needs of development ; consultation and public debates, including the local population and the formulation of a direction of short, medium or long term strategic action and their transposition through a portfolio of projects. Only through

  3. Development of an EAM potential for zinc and its application to the growth of nanoparticles.

    Science.gov (United States)

    Römer, F; Braun, S; Kraska, T

    2009-05-28

    In the context of the investigation of particle formation, a potential model by means of the embedded atom method is developed for the hexagonal close packed metal zinc. This type of model includes many-body interactions caused by delocalised electrons in metals. The effective core charge as function of the distance is calculated here by an integral over the electron distribution function rather than fitting it to experimental data. In addition, the dimer potential is included in the parameterisation because we focus on the formation of nanoparticles from the vapour phase. With this potential model, the growth of zinc clusters consisting of 125 to 1000 atoms is investigated, which takes place at elevated temperatures in a liquid-like cluster state. The growing clusters are embedded in an argon carrier gas atmosphere which regulates the cluster temperature. The average thermal expansion of the clusters and the different lattice constants are analysed. For the determination of the cluster structure, the common-neighbour analysis method is extended to hexagonal close packed surface structures. During growth, small clusters with less than approximately 60 atoms develop transient icosahedral structure before transforming into hexagonal close-packed structure. The surface of the clusters exhibits a transformation from planes with high surface energy to the most stable ones. Besides ambiguous surface structures the final clusters are almost completely in an hexagonal close packed structure.

  4. K ocenke potenciala razvitija prigranichnyh regionov [On the assessment of cross-border regions' development potential

    Directory of Open Access Journals (Sweden)

    Bilchak Mikhail

    2011-01-01

    Full Text Available This article sets out to assess the potential of cross-border region development on the basis of theoretical and methodological materials. The study examines the Kaliningrad region and Warmian-Masurian Voivodeship. The article is focused on the modelling of interindustry balance and export/import functions of border territories.

  5. Intrinsic motivation and metacognition as predictors of learning potential in patients with remitted schizophrenia.

    Science.gov (United States)

    Tas, Cumhur; Brown, Elliot C; Esen-Danaci, Aysen; Lysaker, Paul H; Brüne, Martin

    2012-08-01

    Previous research has suggested that neurocognitive functioning predicts best the potential of patients with schizophrenia to acquire newly learned material, which, in turn may impact patients' social functioning. Recent studies have also shown that intrinsic motivation and metacognitive abilities play a decisive role in social functioning in schizophrenia. Accordingly, the present study sought to examine the relationship between intelligence, motivation, metacognition, and learning during a cognitive remediation experimental training. We hypothesized that metacognition and intrinsic motivation would have a strong relationship and independently predict learning potential. Thirty-two patients with schizophrenia who fulfilled the criteria of functional remission were recruited. In a pre-training-post experimental design, patients' learning potential was assessed using previously defined cognitive remediation training for WCST. Intrinsic motivation was examined using Intrinsic Motivation Inventory for schizophrenia; mastery, a domain of metacognition, was measured using the Metacognitive Assessment Scale. Metacognition significantly correlated with subdomains of intrinsic motivation. Patients with higher intrinsic motivation and preserved metacognition improved more in the learning paradigm compared to poorly motivated patients and patients with reduced metacognitive abilities. In particular, "mastery" was determined as an independent predictor of learning potential. Motivation and metacognition are important predictors of learning in schizophrenia. Psychological interventions in schizophrenia may therefore consider incorporating techniques to stimulate metacognitive and motivational abilities as well as developing individualized training programs. Copyright © 2012 Elsevier Ltd. All rights reserved.

  6. THE POTENTIAL OF FEMALE ENTREPRENEURSHIP AS A REGIONAL GROWTH AND DEVELOPMENT ENGINE IN THE WESTERN ROMANIA

    Directory of Open Access Journals (Sweden)

    Pop Cohut Ioana

    2011-07-01

    Full Text Available Starting from the objectives, activities, and the results of the empirical, quantitative, and qualitative research carried out in the AntrES project (AntrES - Project acronym "Entrepreneurship and Equal Opportunities. A new school for women entrepreneurship" – Antreprenoriatul şi egalitatea de şanse. Un nou model de şcoală antreprenorială pentru femei, during the two years of implementation, in the Western Romania referring to the new businesses start up; business development; the motivation and difficulties of female entrepreneurs and potentially enterprising women; of their perceptions regarding the need for entrepreneurship education, the role of female entrepreneurship promotion and the impact of the successful models on new businesses start up – this paper presents directions of action meant to emphasize and support the potential of the female entrepreneurship in Romania, as a regional growth and development engine.

  7. Nuclear desalting potential for developing countries

    International Nuclear Information System (INIS)

    1969-01-01

    Nuclear power, having proved its success in large units, now poses problems for application in developing countries. Possible solutions for electricity supply, desalting systems and agricultural development are suggested by Joseph R. Wilson, of the Agency's Division of Nuclear Power and Reactors. His article is adapted from a lecture to students in Switzerland. (author)

  8. 14 CFR 121.406 - Credit for previous CRM/DRM training.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 3 2010-01-01 2010-01-01 false Credit for previous CRM/DRM training. 121... previous CRM/DRM training. (a) For flightcrew members, the Administrator may credit CRM training received before March 19, 1998 toward all or part of the initial ground CRM training required by § 121.419. (b...

  9. Nuclear power in developing countries: Its potential role and strategies for its deployment. Proceedings

    International Nuclear Information System (INIS)

    2000-01-01

    The demand for energy, especially electricity, in developing countries is expected to grow rapidly in the coming decades as these countries seek to improve the living standards of their growing populations. Substantial growth in developing country energy demand plus a continued heavy reliance of the power sector on fossil fuels is likely to result in an increased dependence of these countries on energy imports and thus to potential deterioration of their terms-of-trade, reduced energy security and, in the absence of costly mitigation measures, severe degradation of the environment and public health, and will also lead to increasing emissions of greenhouse gases. If supply security, health and environmental protection and climate change become pressing policy issues, nuclear power is, in the short to medium term, the only viable non-fossil base load electricity generating alternative (other than hydro where growth potential is limited) that is already meeting 17% of global electricity needs and contributing more than 30% of electricity supplies in 14 countries. It is in the above context that the International Atomic Energy Agency organized this seminar to explore the role of nuclear power in meeting the growing demand for electricity in the developing world, and to identify and discuss suitable ways and means for proper implementation of nuclear power programmes in these countries. Several issues were discussed, in particular, the need and role of nuclear power; economic and financial aspects; technology transfer and national participation; safety, regulation and safeguards; and public acceptance

  10. Nuclear power in developing countries: Its potential role and strategies for its deployment. Proceedings

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-08-01

    The demand for energy, especially electricity, in developing countries is expected to grow rapidly in the coming decades as these countries seek to improve the living standards of their growing populations. Substantial growth in developing country energy demand plus a continued heavy reliance of the power sector on fossil fuels is likely to result in an increased dependence of these countries on energy imports and thus to potential deterioration of their terms-of-trade, reduced energy security and, in the absence of costly mitigation measures, severe degradation of the environment and public health, and will also lead to increasing emissions of greenhouse gases. If supply security, health and environmental protection and climate change become pressing policy issues, nuclear power is, in the short to medium term, the only viable non-fossil base load electricity generating alternative (other than hydro where growth potential is limited) that is already meeting 17% of global electricity needs and contributing more than 30% of electricity supplies in 14 countries. It is in the above context that the International Atomic Energy Agency organized this seminar to explore the role of nuclear power in meeting the growing demand for electricity in the developing world, and to identify and discuss suitable ways and means for proper implementation of nuclear power programmes in these countries. Several issues were discussed, in particular, the need and role of nuclear power; economic and financial aspects; technology transfer and national participation; safety, regulation and safeguards; and public acceptance.

  11. Development and evaluation of camptothecin loaded polymer stabilized nanoemulsion: Targeting potential in 4T1-breast tumour xenograft model.

    Science.gov (United States)

    Sugumaran, Abimanyu; Ponnusamy, Chandrasekar; Kandasamy, Palanivel; Krishnaswami, Venkateshwaran; Palanichamy, Rajaguru; Kandasamy, Ruckmani; Lakshmanan, Manikandan; Natesan, Subramanian

    2018-04-30

    Targeted delivery of anticancer agents is poised to improve cancer therapy, for which polymers can serve as targeting ligands or nanocarriers for chemotherapeutic agents. In this study, we have developed and evaluated the efficacy of a camptothecin (CPT)-loaded polymer stabilized nanoemulsion (PSNE) for the passive targeted delivery to breast cancer. Based on the pseudo-ternary phase diagrams, PSNEs were developed using capmul MCM:poloxamer 407 (4:1), solutol HS 15:simulsol P23 (1:2) and water. CPT polymer mixture was developed by solvent evaporation technique. The PSNEs were characterized for droplet size distribution, plasma protein adsorption, drug release, in-vivo targeting potential, hemolytic potential, cytotoxicity, genotoxicity, in-vivo biodistribution and CPT lactone ring stability. The developed PSNEs showed uniform droplet distribution, extended drug release (76.59±6.12% at 24h), acceptable hemolytic potential, significant cytotoxicity (IC 50 =176±4.3ng/mL) and genotoxicity against MCF-7 cancer cells but low DNA damage potential in human peripheral blood lymphocytes. The efficiency of PSNEs for the targeted delivery of CPT into the tumour regions was documented in 4T1-breast tumour xenografted BALB/c mice. In-vivo biodistribution study shows that 7105.84±568.46ng/g of CPT was passively targeted from PSNE to breast cancer tissue. About 80% of the lactone form was stable for 24h. Taken together, our study provides a promising strategy for developing PSNE-targeted drug delivery system for the breast cancer therapy. Copyright © 2017 Elsevier B.V. All rights reserved.

  12. Prevention of type 2 diabetes mellitus in women with previous gestational diabetes mellitus

    Science.gov (United States)

    Moon, Joon Ho; Kwak, Soo Heon; Jang, Hak C.

    2017-01-01

    Gestational diabetes mellitus (GDM), defined as any degree of glucose intolerance with onset or first recognition during pregnancy, is characterized by underlying maternal defects in the β-cell response to insulin during pregnancy. Women with a previous history of GDM have a greater than 7-fold higher risk of developing postpartum diabetes compared with women without GDM. Various risk factors for postpartum diabetes have been identified, including maternal age, glucose levels in pregnancy, family history of diabetes, pre-pregnancy and postpartum body mass index, dietary patterns, physical activity, and breastfeeding. Genetic studies revealed that GDM shares common genetic variants with type 2 diabetes. A number of lifestyle interventional trials that aimed to ameliorate modifiable risk factors, including diet, exercise, and breastfeeding, succeeded in reducing the incidence of postpartum diabetes, weight retention, and other obesity-related morbidities. The present review summarizes the findings of previous studies on the incidence and risk factors of postpartum diabetes and discusses recent lifestyle interventional trials that attempted to prevent postpartum diabetes. PMID:28049284

  13. An interatomic potential model for molecular dynamics simulation of silicon etching by Br+-containing plasmas

    International Nuclear Information System (INIS)

    Ohta, H.; Iwakawa, A.; Eriguchi, K.; Ono, K.

    2008-01-01

    An interatomic potential model for Si-Br systems has been developed for performing classical molecular dynamics (MD) simulations. This model enables us to simulate atomic-scale reaction dynamics during Si etching processes by Br + -containing plasmas such as HBr and Br 2 plasmas, which are frequently utilized in state-of-the-art techniques for the fabrication of semiconductor devices. Our potential form is based on the well-known Stillinger-Weber potential function, and the model parameters were systematically determined from a database of potential energies obtained from ab initio quantum-chemical calculations using GAUSSIAN03. For parameter fitting, we propose an improved linear scheme that does not require any complicated nonlinear fitting as that in previous studies [H. Ohta and S. Hamaguchi, J. Chem. Phys. 115, 6679 (2001)]. In this paper, we present the potential derivation and simulation results of bombardment of a Si(100) surface using a monoenergetic Br + beam

  14. Status of helium-cooled nuclear power systems. [Development potential

    Energy Technology Data Exchange (ETDEWEB)

    Melese-d' Hospital, G.; Simnad, M

    1977-09-01

    Helium-cooled nuclear power systems offer a great potential for electricity generation when their long-term economic, environmental, conservation and energy self-sufficiency features are examined. The high-temperature gas-cooled reactor (HTGR) has the unique capability of providing high-temperature steam for electric power and process heat uses and/or high-temperature heat for endothermic chemical reactions. A variation of the standard steam cycle HTGR is one in which the helium coolant flows directly from the core to one or more closed cycle gas turbines. The effective use of nuclear fuel resources for electric power and nuclear process heat will be greatly enhanced by the gas-cooled fast breeder reactor (GCFR) currently being developed. A GCFR using thorium in the radial blanket could generate sufficient U-233 to supply the fuel for three HTGRs, or enough plutonium from a depleted uranium blanket to fuel a breeder economy expanding at about 10% per year. The feasibility of utilizing helium to cool a fusion reactor is also discussed. The status of helium-cooled nuclear energy systems is summarized as a basis for assessing their prospects. 50 references.

  15. Implementation of Research and Development Based on Patent Natural Ingredients and Potential Utilization of Tradition Medicine

    Directory of Open Access Journals (Sweden)

    Tommy Hendrix

    2016-12-01

    Full Text Available The results of research and development based on natural ingredients for traditional medicines become an interesting topic to discuss at this point; it’s shown from increasing number in utilization. The use of traditional medicine especially on natural ingredients at this moment becomes effective solution to increase the level of market acceptance in herbal extracts, including an affordable purchase from potential utilization of natural resources which are owned. By using Matheo Patent XE Ver 10.2 as methodology of searching, we can know potentials useful through strategy, research and development, patent analysis and patent collaboration among users in utilization of Natural Ingredient for Traditional Medicine. From the data result shows majority in the field of chemistry for human necessity related to Health; Amusement; Medical or Veterinary Science; Hygiene sectors with total patent 108, family 65. The use of patent analysis is a way to find how the development of technology and products that have been produced and how commercial processes connecting with technology users, especially in traditional medicine. From the data that exist in particular of patents, it is critical to identify the number of patents that has been registered through the innovation process development including technology dissemination is used.

  16. Nurturing Quality of Higher Education through National Ranking: A Potential Empowerment Model for Developing Countries

    Science.gov (United States)

    Kusumastuti, Dyah; Idrus, Nirwan

    2017-01-01

    This paper reviews the recently introduced National Higher Education ranking system in Indonesia in order to evaluate its potential as a sustainable model to improve the quality of higher education in the country. It is a scaffold towards an established world-universities ranking system that may prove formidable for a developing country. This…

  17. Fluorescence quenching studies of potential-dependent DNA reorientation dynamics at glassy carbon electrode surfaces.

    Science.gov (United States)

    Li, Qin; Cui, Chenchen; Higgins, Daniel A; Li, Jun

    2012-09-05

    The potential-dependent reorientation dynamics of double-stranded DNA (ds-DNA) attached to planar glassy carbon electrode (GCE) surfaces were investigated. The orientation state of surface-bound ds-DNA was followed by monitoring the fluorescence from a 6-carboxyfluorescein (FAM6) fluorophore covalently linked to the distal end of the DNA. Positive potentials (i.e., +0.2 V vs open circuit potential, OCP) caused the ds-DNA to align parallel to the electrode surface, resulting in strong dipole-electrode quenching of FAM6 fluorescence. Switching of the GCE potential to negative values (i.e., -0.2 V vs OCP) caused the ds-DNA to reorient perpendicular to the electrode surface, with a concomitant increase in FAM6 fluorescence. In addition to the very fast (submilliseconds) dynamics of the initial reorientation process, slow (0.1-0.9 s) relaxation of FAM6 fluorescence to intermediate levels was also observed after potential switching. These dynamics have not been previously described in the literature. They are too slow to be explained by double layer charging, and chronoamperometry data showed no evidence of such effects. Both the amplitude and rate of the dynamics were found to depend upon buffer concentration, and ds-DNA length, demonstrating a dependence on the double layer field. The dynamics are concluded to arise from previously undetected complexities in the mechanism of potential-dependent ds-DNA reorientation. The possible origins of these dynamics are discussed. A better understanding of these dynamics will lead to improved models for potential-dependent ds-DNA reorientation at electrode surfaces and will facilitate the development of advanced electrochemical devices for detection of target DNAs.

  18. Development of an automated processing system for potential fishing zone forecast

    Science.gov (United States)

    Ardianto, R.; Setiawan, A.; Hidayat, J. J.; Zaky, A. R.

    2017-01-01

    The Institute for Marine Research and Observation (IMRO) - Ministry of Marine Affairs and Fisheries Republic of Indonesia (MMAF) has developed a potential fishing zone (PFZ) forecast using satellite data, called Peta Prakiraan Daerah Penangkapan Ikan (PPDPI). Since 2005, IMRO disseminates everyday PPDPI maps for fisheries marine ports and 3 days average for national areas. The accuracy in determining the PFZ and processing time of maps depend much on the experience of the operators creating them. This paper presents our research in developing an automated processing system for PPDPI in order to increase the accuracy and shorten processing time. PFZ are identified by combining MODIS sea surface temperature (SST) and chlorophyll-a (CHL) data in order to detect the presence of upwelling, thermal fronts and biological productivity enhancement, where the integration of these phenomena generally representing the PFZ. The whole process involves data download, map geo-process as well as layout that are carried out automatically by Python and ArcPy. The results showed that the automated processing system could be used to reduce the operator’s dependence on determining PFZ and speed up processing time.

  19. Potential Relationship between Inadequate Response to DNA Damage and Development of Myelodysplastic Syndrome

    Directory of Open Access Journals (Sweden)

    Ting Zhou

    2015-01-01

    Full Text Available Hematopoietic stem cells (HSCs are responsible for the continuous regeneration of all types of blood cells, including themselves. To ensure the functional and genomic integrity of blood tissue, a network of regulatory pathways tightly controls the proliferative status of HSCs. Nevertheless, normal HSC aging is associated with a noticeable decline in regenerative potential and possible changes in other functions. Myelodysplastic syndrome (MDS is an age-associated hematopoietic malignancy, characterized by abnormal blood cell maturation and a high propensity for leukemic transformation. It is furthermore thought to originate in a HSC and to be associated with the accrual of multiple genetic and epigenetic aberrations. This raises the question whether MDS is, in part, related to an inability to adequately cope with DNA damage. Here we discuss the various components of the cellular response to DNA damage. For each component, we evaluate related studies that may shed light on a potential relationship between MDS development and aberrant DNA damage response/repair.

  20. Mechanisms of developing post-traumatic stress disorder: new targets for drug development and other potential interventions.

    Science.gov (United States)

    Wimalawansa, Sunil J

    2014-01-01

    The post-traumatic stress disorder (PTSD) is defined as a severe anxiety disorder that develops after exposure to an event with actual, threatened, or perceived death or serious injury, or a threat to the physical integrity of oneself or others that results in significant psychological trauma. Moreover, the ability of people to handle acute severe stress experiences varies among individuals. Depending on the underlying personality and resiliency, therefore, PTSD can occur in individuals exposed to exceedingly stressful incidences or those who have encountered seemingly less overwhelming stressors. In addition to severe stressful exposure, multiple other factors including genetic susceptibility; past experiences; cultural, spiritual, and personal beliefs; bullying and harassments; and lack of support at the workplace, social, and home environement may contribute to the development of PTSD. Author investigated multiple potential mechanisms for the development and sustenance of PTSD based on the recent literature and his own experiences and insight. Based on this search, author indicates that among other pathological and biochemical abnormalities, hormonal aberrations are most likely key mechanisms initiating and the maintenance of the PTSD. These pathophysiological neuro-hormonal changes instigate maladaptive learning processes caused by sustained high levels of anxiety and fear, through a hypo-responsive hypothalamic-pituitary axis and hyper-responsive catecholamine system (persistently elevated blood norepinephrine levels and lower than appropriate glucocorticoid levels). In addition to having inappropriately low serum cortisol levels and high epinephrine and norepinephrine levels, patients with PTSD also have mitochondrial dysfunctions and other hormonal abnormalities. Based on these data, author concluded that these pathological, biochemical and sustained neurohormonal abnormalities are likely to influence the structural brain changes, particularly in the

  1. Biofuels: What potential for development?

    International Nuclear Information System (INIS)

    Alazard-Toux, Nathalie

    2010-01-01

    The current production chain of the first generation of biofuels has quite real limits. To overcome them, efforts are being made to develop processes for converting vegetable resources of little worth into fuel. This research focuses both on these resources and on the technology and processes for turning them into fuel

  2. Organizational mechanism for imlementation of the travel agency financial potential development strategy

    Directory of Open Access Journals (Sweden)

    І.V. Saukh

    2017-03-01

    Full Text Available The article discusses the implementation of the financial development strategy as a set of means required for its accomplishment, including consecutive execution of this strategy, creation of the communication channels, distribution of duties between the parties to the strategic plan, and formation of the system of strategic control. The research analyzes the scientific and methodological approaches used to implement the strategy and form the organizational mechanism of this process within the development of the company's financial potential, based on the use of systemic approach and the concept of strategic change. The paper reveals that travel companies are not able to apply the unified approach to accomplish this strategy, because the process of its implementation is creative and informal. Moreover, it is greatly influenced by the activity of each business. The organizational mechanism of this strategic development embraces a complex of levels, stages, instruments and methods of organizational change. Their systemic application contributes to the development of the company's financial strength. The structure of this organizational mechanism is described as the result of the analysis of traditional and situational methodological approaches to the strategy's formalization and implementation. It centers around the concept of strategic change and seamless cooperation of the target, subject-to-object (injunctive and process-related (regulatory subsystems of the developed mechanism. The mechanism allows to pinpoint and implement the strategies aimed at the development of the company's financial resources and its other structural units. In order to simplify the process of coordination of the subjects implementing the strategy in real-time business activities, the operogram for strategic analysis of the financial development is created. It can be used to optimize the duration of this analysis and allocate the company’s resources in the most

  3. Response to health insurance by previously uninsured rural children.

    Science.gov (United States)

    Tilford, J M; Robbins, J M; Shema, S J; Farmer, F L

    1999-08-01

    To examine the healthcare utilization and costs of previously uninsured rural children. Four years of claims data from a school-based health insurance program located in the Mississippi Delta. All children who were not Medicaid-eligible or were uninsured, were eligible for limited benefits under the program. The 1987 National Medical Expenditure Survey (NMES) was used to compare utilization of services. The study represents a natural experiment in the provision of insurance benefits to a previously uninsured population. Premiums for the claims cost were set with little or no information on expected use of services. Claims from the insurer were used to form a panel data set. Mixed model logistic and linear regressions were estimated to determine the response to insurance for several categories of health services. The use of services increased over time and approached the level of utilization in the NMES. Conditional medical expenditures also increased over time. Actuarial estimates of claims cost greatly exceeded actual claims cost. The provision of a limited medical, dental, and optical benefit package cost approximately $20-$24 per member per month in claims paid. An important uncertainty in providing health insurance to previously uninsured populations is whether a pent-up demand exists for health services. Evidence of a pent-up demand for medical services was not supported in this study of rural school-age children. States considering partnerships with private insurers to implement the State Children's Health Insurance Program could lower premium costs by assembling basic data on previously uninsured children.

  4. Abiraterone in metastatic prostate cancer without previous chemotherapy

    NARCIS (Netherlands)

    Ryan, Charles J.; Smith, Matthew R.; de Bono, Johann S.; Molina, Arturo; Logothetis, Christopher J.; de Souza, Paul; Fizazi, Karim; Mainwaring, Paul; Piulats, Josep M.; Ng, Siobhan; Carles, Joan; Mulders, Peter F. A.; Basch, Ethan; Small, Eric J.; Saad, Fred; Schrijvers, Dirk; van Poppel, Hendrik; Mukherjee, Som D.; Suttmann, Henrik; Gerritsen, Winald R.; Flaig, Thomas W.; George, Daniel J.; Yu, Evan Y.; Efstathiou, Eleni; Pantuck, Allan; Winquist, Eric; Higano, Celestia S.; Taplin, Mary-Ellen; Park, Youn; Kheoh, Thian; Griffin, Thomas; Scher, Howard I.; Rathkopf, Dana E.; Boyce, A.; Costello, A.; Davis, I.; Ganju, V.; Horvath, L.; Lynch, R.; Marx, G.; Parnis, F.; Shapiro, J.; Singhal, N.; Slancar, M.; van Hazel, G.; Wong, S.; Yip, D.; Carpentier, P.; Luyten, D.; de Reijke, T.

    2013-01-01

    Abiraterone acetate, an androgen biosynthesis inhibitor, improves overall survival in patients with metastatic castration-resistant prostate cancer after chemotherapy. We evaluated this agent in patients who had not received previous chemotherapy. In this double-blind study, we randomly assigned

  5. Analyses of more than 60,000 exomes questions the role of numerous genes previously associated with dilated cardiomyopathy

    DEFF Research Database (Denmark)

    Nouhravesh, Nina; Ahlberg, Gustav; Ghouse, Jonas

    2016-01-01

    BACKGROUND: Hundreds of genetic variants have been described as disease causing in dilated cardiomyopathy (DCM). Some of these associations are now being questioned. We aimed to identify the prevalence of previously DCM associated variants in the Exome Aggregation Consortium (ExAC), in order...... to identify potentially false-positive DCM variants. METHODS: Variants listed as DCM disease-causing variants in the Human Gene Mutation Database were extracted from ExAC. Pathogenicity predictions for these variants were mined from dbNSFP v 2.9 database. RESULTS: Of the 473 DCM variants listed in HGMD, 148...... (31%) were found in ExAC. The expected number of individuals with DCM in ExAC is 25 based on the prevalence in the general population. Yet, 35 variants were found in more than 25 individuals. In 13 genes, we identified all variants previously associated with DCM; four genes contained variants above...

  6. Squamous cell carcinoma arising in previously burned or irradiated skin

    International Nuclear Information System (INIS)

    Edwards, M.J.; Hirsch, R.M.; Broadwater, J.R.; Netscher, D.T.; Ames, F.C.

    1989-01-01

    Squamous cell carcinoma (SCC) arising in previously burned or irradiated skin was reviewed in 66 patients treated between 1944 and 1986. Healing of the initial injury was complicated in 70% of patients. Mean interval from initial injury to diagnosis of SCC was 37 years. The overwhelming majority of patients presented with a chronic intractable ulcer in previously injured skin. The regional relapse rate after surgical excision was very high, 58% of all patients. Predominant patterns of recurrence were in local skin and regional lymph nodes (93% of recurrences). Survival rates at 5, 10, and 20 years were 52%, 34%, and 23%, respectively. Five-year survival rates in previously burned and irradiated patients were not significantly different (53% and 50%, respectively). This review, one of the largest reported series, better defines SCC arising in previously burned or irradiated skin as a locally aggressive disease that is distinct from SCC arising in sunlight-damaged skin. An increased awareness of the significance of chronic ulceration in scar tissue may allow earlier diagnosis. Regional disease control and survival depend on surgical resection of all known disease and may require radical lymph node dissection or amputation

  7. Investigation of tenuous plasma environment using Active Spacecraft Potential Control (ASPOC) on Magnetospheric Multiscale (MMS) Mission

    Science.gov (United States)

    Nakamura, Rumi; Jeszenszky, Harald; Torkar, Klaus; Andriopoulou, Maria; Fremuth, Gerhard; Taijmar, Martin; Scharlemann, Carsten; Svenes, Knut; Escoubet, Philippe; Prattes, Gustav; Laky, Gunter; Giner, Franz; Hoelzl, Bernhard

    2015-04-01

    The NASA's Magnetospheric Multiscale (MMS) Mission is planned to be launched on March 12, 2015. The scientific objectives of the MMS mission are to explore and understand the fundamental plasma physics processes of magnetic reconnection, particle acceleration and turbulence in the Earth's magnetosphere. The region of scientific interest of MMS is in a tenuous plasma environment where the positive spacecraft potential reaches an equilibrium at several tens of Volts. An Active Spacecraft Potential Control (ASPOC) instrument neutralizes the spacecraft potential by releasing positive charge produced by indium ion emitters. ASPOC thereby reduces the potential in order to improve the electric field and low-energy particle measurement. The method has been successfully applied on other spacecraft such as Cluster and Double Star. Two ASPOC units are present on each of the MMS spacecraft. Each unit contains four ion emitters, whereby one emitter per instrument is operated at a time. ASPOC for MMS includes new developments in the design of the emitters and the electronics enabling lower spacecraft potentials, higher reliability, and a more uniform potential structure in the spacecraft's sheath compared to previous missions. Model calculations confirm the findings from previous applications that the plasma measurements will not be affected by the beam's space charge. A perfectly stable spacecraft potential precludes the utilization of the spacecraft as a plasma probe, which is a conventional technique used to estimate ambient plasma density from the spacecraft potential. The small residual variations of the potential controlled by ASPOC, however, still allow to determine ambient plasma density by comparing two closely separated spacecraft and thereby reconstructing the uncontrolled potential variation from the controlled potential. Regular intercalibration of controlled and uncontrolled potentials is expected to increase the reliability of this new method.

  8. Analyzing the greenhouse gas impact potential of smallholder development actions across a global food security program

    Science.gov (United States)

    Grewer, Uwe; Nash, Julie; Gurwick, Noel; Bockel, Louis; Galford, Gillian; Richards, Meryl; Costa Junior, Ciniro; White, Julianna; Pirolli, Gillian; Wollenberg, Eva

    2018-04-01

    This article analyses the greenhouse gas (GHG) impact potential of improved management practices and technologies for smallholder agriculture promoted under a global food security development program. Under ‘business-as-usual’ development, global studies on the future of agriculture to 2050 project considerable increases in total food production and cultivated area. Conventional cropland intensification and conversion of natural vegetation typically result in increased GHG emissions and loss of carbon stocks. There is a strong need to understand the potential greenhouse gas impacts of agricultural development programs intended to achieve large-scale change, and to identify pathways of smallholder agricultural development that can achieve food security and agricultural production growth without drastic increases in GHG emissions. In an analysis of 134 crop and livestock production systems in 15 countries with reported impacts on 4.8 million ha, improved management practices and technologies by smallholder farmers significantly reduce GHG emission intensity of agricultural production, increase yields and reduce post-harvest losses, while either decreasing or only moderately increasing net GHG emissions per area. Investments in both production and post-harvest stages meaningfully reduced GHG emission intensity, contributing to low emission development. We present average impacts on net GHG emissions per hectare and GHG emission intensity, while not providing detailed statistics of GHG impacts at scale that are associated to additional uncertainties. While reported improvements in smallholder systems effectively reduce future GHG emissions compared to business-as-usual development, these contributions are insufficient to significantly reduce net GHG emission in agriculture beyond current levels, particularly if future agricultural production grows at projected rates.

  9. ACCELERATING CONSTRUCTION INDUSTRY DEVELOPMENT

    Directory of Open Access Journals (Sweden)

    Mohan M. Kumaraswamy

    2006-06-01

    Full Text Available The needs for construction industry development are initially viewed from the broader perspectives of imperatives for infrastructure development and national development. All these are clearly more critical in developing countries. A non-exhaustive set of potential drivers and common barriers to construction industry development is identified from previous research. These suggest the usefulness of consolidating a cluster of recent proposals and exercises aiming at (a construction organization development in terms of an over-arching management support system model, as well as improved information and knowledge management; and (b project team development in the context of relationally integrated teams and supply chains, joint risk management and ‘technology and knowledge exchange’ in joint ventures, as well as longer term public private partnerships. These apparently disparate research thrusts are threaded together into a pattern that may inspire, if not feed, specific research and development (R & D agendas for construction industry development in different countries according to their own priorities, constraints and stages of infrastructure and national development.

  10. Characterization of structure and development of models to quantify wood potential of an unmanaged Araucaria angustifolia stand

    Directory of Open Access Journals (Sweden)

    Rafaella De Angeli Curto

    2014-12-01

    Full Text Available The objective of this study was to characterize of an unmanaged stand of Araucaria angustifolia and to development of models to quantify the wood potential, aiming to support the development of forest management plans in stands with similar conditions. The work was developed into a stand established in 1946, in National Forest of Açungui, in Campo Largo County, Paraná State, Brazil. There was only one thinning in the stand, between 1970 and 1980. From the frequency of individuals in each diametric class, it was observed the condition of stagnation and competition with cohort in the beginning of class distribution. With the application of the probability density function of Weibull-3P, Trorey model, and the 5th polynomial by diameter class, it was possible to confirm the stock estimative of timber volume of the stand. This analysis indicated that the stand presents average annual wood production smaller than the species potential. So it is recommended the thinning to promote growth of remnant trees. With the probability density function of Weibull-3p, that was selected, it is possible to project the diametric distribution of the stand, when analyzed complementarily with growth diameter information, if the stand remains unmanaged. Certainly, the optimum potential of timber production could have been manifested if the stand were managed during the cycle planed.

  11. Developing global climate anomalies suggest potential disease risks for 2006-2007.

    Science.gov (United States)

    Anyamba, Assaf; Chretien, Jean-Paul; Small, Jennifer; Tucker, Compton J; Linthicum, Kenneth J

    2006-12-28

    El Niño/Southern Oscillation (ENSO) related climate anomalies have been shown to have an impact on infectious disease outbreaks. The Climate Prediction Center of the National Oceanic and Atmospheric Administration (NOAA/CPC) has recently issued an unscheduled El Niño advisory, indicating that warmer than normal sea surface temperatures across the equatorial eastern Pacific may have pronounced impacts on global tropical precipitation patterns extending into the northern hemisphere particularly over North America. Building evidence of the links between ENSO driven climate anomalies and infectious diseases, particularly those transmitted by insects, can allow us to provide improved long range forecasts of an epidemic or epizootic. We describe developing climate anomalies that suggest potential disease risks using satellite generated data. Sea surface temperatures (SSTs) in the equatorial east Pacific ocean have anomalously increased significantly during July - October 2006 indicating the typical development of El Niño conditions. The persistence of these conditions will lead to extremes in global-scale climate anomalies as has been observed during similar conditions in the past. Positive Outgoing Longwave Radiation (OLR) anomalies, indicative of severe drought conditions, have been observed across all of Indonesia, Malaysia and most of the Philippines, which are usually the first areas to experience ENSO-related impacts. This dryness can be expected to continue, on average, for the remainder of 2006 continuing into the early part of 2007. During the period November 2006 - January 2007 climate forecasts indicate that there is a high probability for above normal rainfall in the central and eastern equatorial Pacific Islands, the Korean Peninsula, the U.S. Gulf Coast and Florida, northern South America and equatorial east Africa. Taking into consideration current observations and climate forecast information, indications are that the following regions are at increased

  12. Development of EEM based silicon–water and silica–water wall potentials for non-reactive molecular dynamics simulations

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Junghan; Iype, Eldhose; Frijns, Arjan J.H.; Nedea, Silvia V.; Steenhoven, Anton A. van

    2014-07-01

    Molecular dynamics simulations of heat transfer in gases are computationally expensive when the wall molecules are explicitly modeled. To save computational time, an implicit boundary function is often used. Steele's potential has been used in studies of fluid–solid interface for a long time. In this work, the conceptual idea of Steele's potential was extended in order to simulate water–silicon and water–silica interfaces. A new wall potential model is developed by using the electronegativity-equalization method (EEM), a ReaxFF empirical force field and a non-reactive molecular dynamics package PumMa. Contact angle simulations were performed in order to validate the wall potential model. Contact angle simulations with the resulting tabulated wall potentials gave a silicon–water contact angle of 129°, a quartz–water contact angle of 0°, and a cristobalite–water contact angle of 40°, which are in reasonable agreement with experimental values.

  13. Generating carbon finance through avoided deforestation and its potential to create climatic, conservation and human development benefits.

    Science.gov (United States)

    Ebeling, Johannes; Yasué, Maï

    2008-05-27

    Recent proposals to compensate developing countries for reducing emissions from deforestation (RED) under forthcoming climate change mitigation regimes are receiving increasing attention. Here we demonstrate that if RED credits were traded on international carbon markets, even moderate decreases in deforestation rates could generate billions of Euros annually for tropical forest conservation. We also discuss the main challenges for a RED mechanism that delivers real climatic benefits. These include providing sufficient incentives while only rewarding deforestation reductions beyond business-as-usual scenarios, addressing risks arising from forest degradation and international leakage, and ensuring permanence of emission reductions. Governance may become a formidable challenge for RED because some countries with the highest RED potentials score poorly on governance indices. In addition to climate mitigation, RED funds could help achieve substantial co-benefits for biodiversity conservation and human development. However, this will probably require targeted additional support because the highest biodiversity threats and human development needs may exist in countries that have limited income potentials from RED. In conclusion, how successfully a market-based RED mechanism can contribute to climate change mitigation, conservation and development will strongly depend on accompanying measures and carefully designed incentive structures involving governments, business, as well as the conservation and development communities.

  14. Positive Youth Development from Sport to Life: Explicit or Implicit Transfer?

    Science.gov (United States)

    Turnnidge, Jennifer; Côté, Jean; Hancock, David J.

    2014-01-01

    While previous studies indicate that participation in sport has the potential to facilitate positive developmental outcomes, there is a lack of consensus regarding the possible transfer of these outcomes to other environments (i.e., school or work). An important issue within the positive development literature concerns how sport programs should…

  15. Do soil organic carbon levels affect potential yields and nitrogen use efficiency?

    DEFF Research Database (Denmark)

    Oelofse, Myles; Markussen, Bo; Knudsen, Leif

    2015-01-01

    Soil organic carbon (SOC) is broadly recognised as an important parameter affecting soil quality, and can therefore contribute to improving a number of soil properties that influence crop yield. Previous research generally indicates that soil organic carbon has positive effects on crop yields......, the yield with no fertiliser N application and the N use efficiency would be positively affected by SOC level. A statistical model was developed to explore relationships between SOC and potential yield, yields at zero N application and N use efficiency (NUE). The model included a variety of variables...

  16. The Social Form of Wealth as a Dominant in the Development Potential of Modern Macroeconomic Systems

    Directory of Open Access Journals (Sweden)

    Silantiev Oleh I.

    2018-02-01

    Full Text Available The publication is aimed at researching the role of the social form of wealth and its constituents in the development potential of modern macroeconomic systems. The essence of social wealth has been disclosed and the concept of «social form of wealth» has been defined. The ability of social capital to promote materialization of the potential reserves of development of society is characterized, that is caused by its productive value when it develops itself and develops possibilities of increase of other forms of wealth in certain combinations. The ability of social capital to be integrated into a reproduced process at almost any stage of the latter has been determined. Presence of a controversy between the traditional capitalist way of production of wealth (with a focus on the growth of private wealth corporations and post-industrial (which in practice is manifested in the asymmetry of information has been proved. It has been determined that the social capital is considered as an individual property of everyone, which, however, can become a public (collective resource in whole or in part. The importance of the carried out research is an improvement of theoretical approaches to understanding how the volume of social wealth, accumulated by macroeconomic systems, impacts economic-social development. Prospects for further research are an in-depth study of the relationship between the social wealth of macroeconomic systems and the volume of their wealth.

  17. Facilitating the selection and creation of accurate interatomic potentials with robust tools and characterization

    Science.gov (United States)

    Trautt, Zachary T.; Tavazza, Francesca; Becker, Chandler A.

    2015-10-01

    The Materials Genome Initiative seeks to significantly decrease the cost and time of development and integration of new materials. Within the domain of atomistic simulations, several roadblocks stand in the way of reaching this goal. While the NIST Interatomic Potentials Repository hosts numerous interatomic potentials (force fields), researchers cannot immediately determine the best choice(s) for their use case. Researchers developing new potentials, specifically those in restricted environments, lack a comprehensive portfolio of efficient tools capable of calculating and archiving the properties of their potentials. This paper elucidates one solution to these problems, which uses Python-based scripts that are suitable for rapid property evaluation and human knowledge transfer. Calculation results are visible on the repository website, which reduces the time required to select an interatomic potential for a specific use case. Furthermore, property evaluation scripts are being integrated with modern platforms to improve discoverability and access of materials property data. To demonstrate these scripts and features, we will discuss the automation of stacking fault energy calculations and their application to additional elements. While the calculation methodology was developed previously, we are using it here as a case study in simulation automation and property calculations. We demonstrate how the use of Python scripts allows for rapid calculation in a more easily managed way where the calculations can be modified, and the results presented in user-friendly and concise ways. Additionally, the methods can be incorporated into other efforts, such as openKIM.

  18. Facilitating the selection and creation of accurate interatomic potentials with robust tools and characterization

    International Nuclear Information System (INIS)

    Trautt, Zachary T; Tavazza, Francesca; Becker, Chandler A

    2015-01-01

    The Materials Genome Initiative seeks to significantly decrease the cost and time of development and integration of new materials. Within the domain of atomistic simulations, several roadblocks stand in the way of reaching this goal. While the NIST Interatomic Potentials Repository hosts numerous interatomic potentials (force fields), researchers cannot immediately determine the best choice(s) for their use case. Researchers developing new potentials, specifically those in restricted environments, lack a comprehensive portfolio of efficient tools capable of calculating and archiving the properties of their potentials. This paper elucidates one solution to these problems, which uses Python-based scripts that are suitable for rapid property evaluation and human knowledge transfer. Calculation results are visible on the repository website, which reduces the time required to select an interatomic potential for a specific use case. Furthermore, property evaluation scripts are being integrated with modern platforms to improve discoverability and access of materials property data. To demonstrate these scripts and features, we will discuss the automation of stacking fault energy calculations and their application to additional elements. While the calculation methodology was developed previously, we are using it here as a case study in simulation automation and property calculations. We demonstrate how the use of Python scripts allows for rapid calculation in a more easily managed way where the calculations can be modified, and the results presented in user-friendly and concise ways. Additionally, the methods can be incorporated into other efforts, such as openKIM. (paper)

  19. Study on the Potential Development of Rainwater Utilization in the Hilly City of Southern China

    Science.gov (United States)

    Fu, Xiaoran; Liu, Jiahong; Shao, Weiwei; Zhang, Haixing

    2017-12-01

    Aimed at the current flood problems and the contradiction between supply and demand of water resources in the southern cities of China, the comprehensive utilization of Urban Rainwater Resources (URRs) is a significant solution. At present, the research on the comprehensive utilization system of urban rainwater resources in China is still immature, especially the lack of a comprehensive method for the comprehensive utilization of the rainwater and flood resources in the south. Based on the current mode for utilization of URRs at home and abroad, Fenghuang County in Hunan Province was taken as a case of study, which is a typical mountainous city in the southern China. And the potential development of URRs was simulated and evaluated with a comparison of before and after the exploitation and utilization of URRs in this paper. The reduction effect of flood and waterlogging on the ancient city area is analyzed from SWMM. The simulation results show that the potential of exploitation and utilization of URRs in Fenghuang county is remarkable under the mode of exploitation and utilization which is given priority to flood prevention and control, and the annual development potential is 4.865×105 m3. The rainwater utilization measures of flood control effect is obvious with this mode, and the relevant research results can provide theoretical and technical support for enhancing urban water security capability, water conservation capacity, and disaster mitigation of urban flood.

  20. Developing tools to identify marginal lands and assess their potential for bioenergy production

    Science.gov (United States)

    Galatsidas, Spyridon; Gounaris, Nikolaos; Dimitriadis, Elias; Rettenmaier, Nils; Schmidt, Tobias; Vlachaki, Despoina

    2017-04-01

    The term "marginal land" is currently intertwined in discussions about bioenergy although its definition is neither specific nor firm. The uncertainty arising from marginal land classification and quantification is one of the major constraining factors for its potential use. The clarification of political aims, i.e. "what should be supported?" is also an important constraining factor. Many approaches have been developed to identify marginal lands, based on various definitions according to the management goals. Concerns have been frequently raised regarding the impacts of marginal land use on environment, ecosystem services and sustainability. Current tools of soil quality and land potentials assessment fail to meet the needs of marginal land identification and exploitation for biomass production, due to the lack of comprehensive analysis of interrelated land functions and their quantitative evaluation. Land marginality is determined by dynamic characteristics in many cases and may therefore constitute a transitional state, which requires reassessment in due time. Also, marginal land should not be considered simply a dormant natural resource waiting to be used, since it may already provide multiple benefits and services to society relating to wildlife, biodiversity, carbon sequestration, etc. The consequences of cultivating such lands need to be fully addressed to present a balanced view of their sustainable potential for bioenergy. This framework is the basis for the development of the SEEMLA tools, which aim at supporting the identification, assessment, management of marginal lands in Europe and the decision-making for sustainable biomass production of them using appropriate bioenergy crops. The tools comprise two applications, a web-based one (independent of spatial data) and a GIS-based application (land regionalization on the basis of spatial data), which both incorporate: - Land resource characteristics, restricting the cultivation of agricultural crops but