WorldWideScience

Sample records for previous research efforts

  1. Summary of process research analysis efforts

    Science.gov (United States)

    Burger, D. R.

    1985-01-01

    A summary of solar-cell process research analysis efforts was presented. Process design and cell design are interactive efforts where technology from integrated circuit processes and other processes are blended. The primary factors that control cell efficiency are: (1) the bulk parameters of the available sheet material, (2) the retention and enhancement of these bulk parameters, and (3) the cell design and the cost to produce versus the finished cells performance. The process sequences need to be tailored to be compatible with the sheet form, the cell shape form, and the processing equipment. New process options that require further evaluation and utilization are lasers, robotics, thermal pulse techniques, and new materials. There are numerous process control techniques that can be adapted and used that will improve product uniformity and reduced costs. Two factors that can lead to longer life modules are the use of solar cell diffusion barriers and improved encapsulation.

  2. Green Roof Research through EPA's Regional Applied Research Effort - slides

    Science.gov (United States)

    The U.S. Environmental Protection Agency’s (EPA) Regional Applied Research Effort (RARE) allows the Regions of the EPA to choose research projects to be performed in partnership with EPA’s Office of Research and Development (ORD). Over the last decade, several green roof projects...

  3. Green Roof Research through EPA's Regional Applied Research Effort

    Science.gov (United States)

    ABSTRACT The U.S. Environmental Protection Agency’s (EPA) Regional Applied Research Effort (RARE) allows the Regions of the EPA to choose research projects to be performed in partnership with EPA’s Office of Research and Development (ORD). Over the last decade, several green roo...

  4. Regionally Applied Research Efforts (RARE) Report titled " ...

    Science.gov (United States)

    The traditional methodology for health risk assessment used by the U. S. Environmental Protection Agency (EPA) is based on the use of exposure assumptions (e.g. exposure duration, food ingestion rate, body weight, etc.) that represent the entire American population, either as a central tendency exposure (e.g. average, median) or as a reasonable maximum exposure (e.g. 95% upper confidence limit). Unfortunately, EPA lacked exposure information for assessing health risks for New England regional tribes sustaining a tribal subsistence way of life. As a riverine tribe, the Penobscot culture and traditions are inextricably tied to the Penobscot River watershed. It is through hunting, fishing, trapping, gathering and making baskets, pottery, moccasins, birch-bark canoes and other traditional practices that the Penobscot culture and people are sustained. The Penobscot River receives a variety of pollutant discharges leaving the Penobscot Indian Nation (PIN) questioning the ecological health and water quality of the river and how this may affect the practices that sustain their way of life. The objectives of this Regional Applied Research Effort (RARE) study were to: (1) Develop culturally sensitive methodologies for assessing the potential level of exposure to contaminants that Penobscot Indian Nation tribal members may have from maintaining tribal sustenance practices; (2) Conduct field surveys and laboratory analysis on targeted flora and fauna for chemical expo

  5. Successive Research: A Strategy for Building on Previous Research.

    Science.gov (United States)

    Noble, Mary Anne

    1979-01-01

    Describes an approach to clinical research used by the author in teaching graduate nursing students, involving replication and expansion of a primary study of hospital intensive care units. This approach provided valuable experience as well as validated data about clinical practice. Discusses advantages and disadvantages in the approach. (MF)

  6. Comparative assessment of world research efforts on magnetic confinement fusion

    International Nuclear Information System (INIS)

    McKenney, B.L.; McGrain, M.; Rutherford, P.H.

    1990-02-01

    This report presents a comparative assessment of the world's four major research efforts on magnetic confinement fusion, including a comparison of the capabilities in the Soviet Union, the European Community (Western Europe), Japan, and the United States. A comparative evaluation is provided in six areas: tokamak confinement; alternate confinement approaches; plasma technology and engineering; and fusion computations. The panel members are involved actively in fusion-related research, and have extensive experience in previous assessments and reviews of the world's four major fusion programs. Although the world's four major fusion efforts are roughly comparable in overall capabilities, two conclusions of this report are inescapable. First, the Soviet fusion effort is presently the weakest of the four programs in most areas of the assessment. Second, if present trends continue, the United States, once unambiguously the world leader in fusion research, will soon lose its position of leadership to the West European and Japanese fusion programs. Indeed, before the middle 1990s, the upgraded large-tokamak facilities, JT-60U (Japan) and JET (Western Europe), are likely to explore plasma conditions and operating regimes well beyond the capabilities of the TFTR tokamak (United States). In addition, if present trends continue in the areas of fusion nuclear technology and materials, and plasma technology and materials, and plasma technology development, the capabilities of Japan and Western Europe in these areas (both with regard to test facilities and fusion-specific industrial capabilities) will surpass those of the United States by a substantial margin before the middle 1990s

  7. 48 CFR 35.009 - Subcontracting research and development effort.

    Science.gov (United States)

    2010-10-01

    ... ACQUISITION REGULATION SPECIAL CATEGORIES OF CONTRACTING RESEARCH AND DEVELOPMENT CONTRACTING 35.009 Subcontracting research and development effort. Since the selection of R&D contractors is substantially based on... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Subcontracting research...

  8. Overview of NASA Magnet and Linear Alternator Research Efforts

    Science.gov (United States)

    Geng, Steven M.; Niedra, Janis M.; Schwarze, Gene E.

    2005-02-01

    The Department of Energy, Lockheed Martin, Stirling Technology Company, and NASA Glenn Research Center are developing a high-efficiency, 110 watt Stirling Radioisotope Generator (SRG110) for NASA Space Science missions. NASA Glenn is conducting in-house research on rare earth permanent magnets and on linear alternators to assist in developing a free-piston Stirling convertor for the SRG110 and for developing advanced technology. The permanent magnet research efforts include magnet characterization, short-term magnet aging tests, and long-term magnet aging tests. Linear alternator research efforts have begun just recently at GRC with the characterization of a moving iron type linear alternator using GRC's alternator test rig. This paper reports on the progress and future plans of GRC's magnet and linear alternator research efforts.

  9. A Critical Examination of My Qualitative Research Efforts in Turkey

    Directory of Open Access Journals (Sweden)

    Yıldız Uzuner

    2015-12-01

    Full Text Available . Today, it is known and widely accepted that researchers must know the research paradigms and develop skills and non-dogmatic attitudes for conducting and evaluating studies in any methodology. Quantitative research methodology is more common while qualitative research is relatively new in Turkey. Researchers who have not developed sufficient knowledge and experiences in qualitative study would create nonevidence based and non-ethical research projects. This creates threats to the research community. In order to improve and be competent in any methodology, it is important to review and critically analyze the completed dissertations, thesis and the journal articles emerged from those research efforts. In this effort self-reflection of one’s own research effort is essential. In this paper as an experienced researcher the author shares her experiences in supervising theses and dissertations and conducting her own research projects in qualitative research methodology in the last 20 years in Turkey. In the light of the literature considering various aspects she discusses advantages and disadvantages conducting qualitative studies in Turkey. Considering the disadvantages, the author came up with the idea of keeping thinking positively, acting modestly, being patient, learning how to deal with the authority, learning how to deal with the exploiters, working hard, never giving up, focusing on the target, being assertive when necessary, and so keeping going in the scientific way.

  10. Research Note Effects of previous cultivation on regeneration of ...

    African Journals Online (AJOL)

    We investigated the effects of previous cultivation on regeneration potential under miombo woodlands in a resettlement area, a spatial product of Zimbabwe's land reforms. We predicted that cultivation would affect population structure, regeneration, recruitment and potential grazing capacity of rangelands. Plant attributes ...

  11. Physics Education Research efforts to promote diversity: Challenges and opportunities

    Science.gov (United States)

    Brahmia, Suzanne

    2015-04-01

    We begin this talk with a brief description of the gender and ethnic diversity of the physics community. We then discuss several current efforts within Physics Education Research that have the potential to further our understanding of issues surrounding underrepresentation. These efforts include research into (1) the role of community and strategies for developing effective communities; (2) physics identity and self-efficacy; (3) the affordances that students from underrepresented groups bring to physics learning; (4) socioeconomics and its impact on mathematization. One of the challenges to conducting this research is the relatively small proportion of underrepresented minority students in current physics classes, and the small number of women in physics and engineering majors. In collaboration with Stephen Kanim, New Mexico State University.

  12. National High Frequency Radar Network (hfrnet) and Pacific Research Efforts

    Science.gov (United States)

    Hazard, L.; Terrill, E. J.; Cook, T.; de Paolo, T.; Otero, M. P.; Rogowski, P.; Schramek, T. A.

    2016-12-01

    The U.S. High Frequency Radar Network (HFRNet) has been in operation for over ten years with representation from 31 organizations spanning academic institutions, state and local government agencies, and private organizations. HFRNet currently holds a collection from over 130 radar installations totaling over 10 million records of surface ocean velocity measurements. HFRNet is a primary example of inter-agency and inter-institutional partnerships for improving oceanographic research and operations. HF radar derived surface currents have been used in several societal applications including coastal search and rescue, oil spill response, water quality monitoring and marine navigation. Central to the operational success of the large scale network is an efficient data management, storage, access, and delivery system. The networking of surface current mapping systems is characterized by a tiered structure that extends from the individual field installations to local regional operations maintaining multiple sites and on to centralized locations aggregating data from all regions. The data system development effort focuses on building robust data communications from remote field locations (sites) for ingestion into the data system via data on-ramps (Portals or Site Aggregators) to centralized data repositories (Nodes). Centralized surface current data enables the aggregation of national surface current grids and allows for ingestion into displays, management tools, and models. The Coastal Observing Research and Development Center has been involved in international relationships and research in the Philippines, Palau, and Vietnam. CORDC extends this IT architecture of surface current mapping data systems leveraging existing developments and furthering standardization of data services for seamless integration of higher level applications. Collaborations include the Philippine Atmospheric Geophysical and Astronomical Services Administration (PAGASA), The Coral Reef Research

  13. Research efforts for the resolution of hydrogen risk

    Directory of Open Access Journals (Sweden)

    Seong-Wan Hong

    2015-02-01

    Full Text Available During the past 10 years, the Korea Atomic Energy Research Institute (KAERI has performed a study to control hydrogen gas in the containment of the nuclear power plants. Before the Fukushima accident, analytical activities for gas distribution analysis in experiments and plants were primarily conducted using a multidimensional code: the GASFLOW. After the Fukushima accident, the COM3D code, which can simulate a multidimensional hydrogen explosion, was introduced in 2013 to complete the multidimensional hydrogen analysis system. The code validation efforts of the multidimensional codes of the GASFLOW and the COM3D have continued to increase confidence in the use of codes using several international experimental data. The OpenFOAM has been preliminarily evaluated for APR1400 containment, based on experience from coded validation and the analysis of hydrogen distribution and explosion using the multidimensional codes, the GASFLOW and the COM3D. Hydrogen safety in nuclear power has become a much more important issue after the Fukushima event in which hydrogen explosions occurred. The KAERI is preparing a large-scale test that can be used to validate the performance of domestic passive autocatalytic recombiners (PARs and can provide data for the validation of the severe accident code being developed in Korea.

  14. Global unbalance in seaweed production, research effort and biotechnology markets.

    Science.gov (United States)

    Mazarrasa, Inés; Olsen, Ylva S; Mayol, Eva; Marbà, Núria; Duarte, Carlos M

    2014-01-01

    Exploitation of the world's oceans is rapidly growing as evidenced by a booming patent market of marine products including seaweed, a resource that is easily accessible without sophisticated bioprospecting technology and that has a high level of domestication globally. The investment in research effort on seaweed aquaculture has recently been identified to be the main force for the development of a biotechnology market of seaweed-derived products and is a more important driver than the capacity of seaweed production. Here, we examined seaweed patent registrations between 1980 and 2009 to assess the growth rate of seaweed biotechnology, its geographic distribution and the types of applications patented. We compare this growth with scientific investment in seaweed aquaculture and with the market of seaweed production. We found that both the seaweed patenting market and the rate of scientific publications are rapidly growing (11% and 16.8% per year respectively) since 1990. The patent market is highly geographically skewed (95% of all registrations belonging to ten countries and the top two holding 65% of the total) compared to the distribution of scientific output among countries (60% of all scientific publications belonging to ten countries and the top two countries holding a 21%), but more homogeneously distributed than the production market (with a 99.8% belonging to the top ten countries, and a 71% to the top two). Food industry was the dominant application for both the patent registrations (37.7%) and the scientific publications (21%) followed in both cases by agriculture and aquaculture applications. This result is consistent with the seaweed taxa most represented. Kelp, which was the target taxa for 47% of the patent registrations, is a traditional ingredient in Asian food and Gracilaria and Ulva, which were the focus of 15% and 13% of the scientific publications respectively, that are also used in more sophisticated applications such as cosmetics, chemical

  15. Current research efforts of EP study in Korea

    International Nuclear Information System (INIS)

    Ryu, C.M.

    2013-01-01

    After the successful demonstration of H mode on KSTAR, the problem of fast-ion driven MHD modes such as Alfven eigenmodes (AEs) and the reverse effects on fast ions of MHD modes is under study in KSTAR. In this paper, I will briefly describe some recent efforts of KSTAR on energetic particle physics study. (J.P.N.)

  16. Future Efforts in Flynn Effect Research: Balancing Reductionism with Holism

    Directory of Open Access Journals (Sweden)

    Michael A. Mingroni

    2014-10-01

    Full Text Available After nearly thirty years of concerted effort by many investigators, the cause or causes of the secular gains in IQ test scores, known as the Flynn effect, remain elusive. In this target article, I offer six suggestions as to how we might proceed in our efforts to solve this intractable mystery. The suggestions are as follows: (1 compare parents to children; (2 consider other traits and conditions; (3 compare siblings; (4 conduct more and better intervention programs; (5 use subtest profile data in context; and (6 quantify the potential contribution of heterosis. This last section contains new simulations of the process of heterosis, which provide a plausible scenario whereby rapid secular changes in multiple genetically influenced traits are possible. If there is any theme to the present paper, it is that future study designs should be simpler and more highly focused, coordinating multiple studies on single populations.

  17. Geoengineering: Basic science and ongoing research efforts in China

    Directory of Open Access Journals (Sweden)

    Long Cao

    2015-09-01

    Full Text Available Geoengineering (also called climate engineering, which refers to large-scale intervention in the Earth's climate system to counteract greenhouse gas-induced warming, has been one of the most rapidly growing areas of climate research as a potential option for tackling global warming. Here, we provide an overview of the scientific background and research progress of proposed geoengineering schemes. Geoengineering can be broadly divided into two categories: solar geoengineering (also called solar radiation management, or SRM, which aims to reflect more sunlight to space, and carbon dioxide removal (CDR, which aims to reduce the CO2 content in the atmosphere. First, we review different proposed geoengineering methods involved in the solar radiation management and carbon dioxide removal schemes. Then, we discuss the fundamental science underlying the climate response to the carbon dioxide removal and solar radiation management schemes. We focus on two basic issues: 1 climate response to the reduction in solar irradiance and 2 climate response to the reduction in atmospheric CO2. Next, we introduce an ongoing geoengineering research project in China that is supported by National Key Basic Research Program. This research project, being the first coordinated geoengineering research program in China, will systematically investigate the physical mechanisms, climate impacts, and risk and governance of a few targeted geoengineering schemes. It is expected that this research program will help us gain a deep understanding of the physical science underlying geoengineering schemes and the impacts of geoengineering on global climate, in particular, on the Asia monsoon region.

  18. research efforts on intelligent transportation system in nigeria

    African Journals Online (AJOL)

    user

    Information System (ATIS) categories as products of research on ITS were developed with data derived from urban trip makers ..... Federal University of Technology, Minna, Nigeria aimed ... advocated for government and private sector driven.

  19. SARNET: An European cooperative effort on LWR severe accident research

    International Nuclear Information System (INIS)

    Micaelli, Jean-Claude; Van Dorsselaere, Jean-Pierre; Chaumont, Bernard; Adroguer, Bernard; Haste, Tim; Bonnet, Jean-Michel; Meyer, Leonhard; Beraha, David; Trambauer, Klaus; Annunziato, Alessandro; Sehgal, Raj

    2006-01-01

    49 organisations network in SARNET (Severe Accident Research and management NETwork) their capacities of research in order to resolve the most important remaining uncertainties and safety issues for enhancing, in regard of Severe Accidents (SA), the safety of existing and future Nuclear Power Plants (NPPs). This project has been defined bearing in mind the necessity to optimise the use of the available means and to constitute sustainable research groups. SARNET tackles the fragmentation that exists between the different R and D national programmes, notably in defining common research programmes and developing common computer tools and methodologies for safety assessment. SARNET comprises most of the actors involved in SA research in Europe. To reach these objectives, all the organizations networked in SARNET contribute to a so-called Joint Programme of Activities (JPA), which can be broken in several elements: - Implementing an advanced communication tool for fostering exchange of information; - Harmonizing and re-orienting the research programmes, and defining commonly new ones; - Analysing commonly the experimental results provided by research programmes in order to elaborate a common understanding of concerned phenomena; - Developing ASTEC code (integral computer code used to predict the NPP behaviour during a postulated SA), which capitalizes in terms of physical models the knowledge produced within SARNET; - Developing Scientific Databases, in which all the results of research programmes are stored; - Developing a common methodology for Probabilistic Safety Assessment (PSA) of NNPs; - Developing educational courses and text (source) books; - Promoting personnel mobility between the various European organisations. A few organizations are covering a wide range of competences though not complete, whereas others are specialized in very specific areas and thus complementarities are developing. The critical mass of competence for performing experiments needed in the

  20. Research on Children's Environmental Programmatic Efforts Pertaining to Fatherhood

    Science.gov (United States)

    Fagan, Jay

    2007-01-01

    Programmatic initiatives for fathers have grown rapidly in early childhood settings during the past decade. This article reviews the research literature on attitudes about father involvement in programs, patterns of father involvement, studies about program development, outcome studies, and correlates of father involvement in programs.…

  1. Analysis of international efforts in energy research and development

    International Nuclear Information System (INIS)

    Rezaiyan, A.J.; Gill, R.T.

    1995-09-01

    Research and experimental development comprise innovative and creative work undertaken systematically to increase the stock of knowledge of science, engineering, and society. This knowledge reserve is used to improve living conditions and standards, including economic growth. Research and development (R ampersand D) expenditures are useful measures of the scale and direction of technological innovation within a country, industry, or scientific field. Administrators concerned with economic growth and performance rely on R ampersand D statistics as one possible type of indicator of technological change. R ampersand D statistics are an essential tool in many government programs and evaluations (OECD 1993). The objective of the analysis was to identify and evaluate R ampersand D funding sources, levels, and trends in the energy sectors of selected industrialized countries (Australia, Belgium, Canada, Denmark, Finland, France, Germany, Italy, Japan, Netherlands, Norway, Sweden, Switzerland, United Kingdom, United States) and the European Union (EU). Fossil fuel technologies, particularly fuel cells and advanced gas turbines, were the focus of the analysis, whose results are presented in this report

  2. Group-effort Applied Research: Expanding Opportunities for Undergraduate Research through Original, Class-Based Research Projects

    Science.gov (United States)

    Moore, Sean D.; Teter, Ken

    2014-01-01

    Undergraduate research clearly enriches the educational development of participating students, but these experiences are limited by the inherent inefficiency of the standard one student-one mentor model for undergraduate research. Group-effort applied research (GEAR) was developed as a strategy to provide substantial numbers of undergraduates with…

  3. Husky Oil's gas migration research effort: An update

    International Nuclear Information System (INIS)

    Schmitz, R.; Carlson, P.B.; Lorenz, G.D.; Watson, M.D.; Erno, B.P.

    1993-01-01

    Gas migration, which is the leakage of gas from outside the wellbore casings of oil and gas wells, has been recognized for many years as a problem but is still not clearly understood. It can exhibit itself as gas pressure on the surface casing, gas migrating through the soil surrounding the casing, or both. The phenomena is particularly visible in the Lloydminster area, in part due to the fact that well density is high and much of the land is under cultivation, making the effects on soil more evident. A research and development program has been initiated to determine the extent and impact of the problem and to identify technical solutions. The magnitude of the problem is discussed, indicating that 1 in 20 wells in Alberta has gas pressure on the surface casing. In the Lloydminster area, nearly half of all wells show indication of gas migration. Industry/regulatory action in the past is discussed, and the search for technical and business solutions is described. It is shown that methane leakage from gas migration is low, and emission from most gas migration wells is comparable to that generated by a typical dairy cow. 8 refs., 6 figs., 4 tabs

  4. Trends of plasma physics and nuclear fusion research life cycle and research effort curve

    International Nuclear Information System (INIS)

    Ohe, Takeru; Kanada, Yasumasa; Momota, Hiromu; Ichikawa, Y.H.

    1979-05-01

    This paper presents a quantitative analysis of research trends in the fields of plasma physics and nuclear fusion. This analysis is based on information retrieval from available data bases such as INSPEC tapes. The results indicate that plasma physics research is now in the maturation phase of its life cycle, and that nuclear fusion research is in its growth phase. This paper indicates that there is a correlation between the number of accumulated papers in the fields of plasma physics and nuclear fusion and the experimentally attained values of the plasma ignition parameter ntT. Using this correlation ''research effort curve'', we forecast that the scientific feasibility of controlled fusion using magnetic confinement systems will be proved around 1983. (author)

  5. Directed Research in Bone Discipline: Refining Previous Research Observations for Space Medicine

    Science.gov (United States)

    Sibonga, Jean D.

    2015-01-01

    Dual-energy X-ray absorptiometry bone mass density, as a sole index, is an insufficient surrogate for fracture; Clinical Practice Guidelines using bone mass density (both World Health Organization and FRAX) are not specific for complicated subjects such as young, healthy persons following prolonged exposure to skeletal unloading (i.e. an attribute of spaceflight); Research data suggest that spaceflight induces changes to astronaut bones that could be profound, possibly irreversible and unlike age-related bone loss on Earth.; There is a need to objectively assess factors across human physiology that are also influenced by spaceflight (e.g., muscle) that contribute to fracture risk. Some of these objective assessments may require innovative technologies, analyses and modeling.; Astronauts are also exposed to novel situations that may overload their bones highlighting a need integrate biomechanics of physical activities into risk assessments.; As we accumulate data, which reflects the biomechanical competence of bone under specific mechanically-loaded scenarios (even activities of daily living), BONE expects Bone Fracture Module to be more sensitive and/or have less uncertainty in its assessments of fracture probability.; Fracture probability drives the requirement for countermeasures. Level of evidence will unlikely be obtained; hence, the Bone Research and Clinical Advisory Panel (like a Data Safety Monitoring Board) will provide the recommendations.

  6. Mentoring to develop research selfefficacy, with particular reference to previously disadvantaged individuals

    OpenAIRE

    S. Schulze

    2010-01-01

    The development of inexperienced researchers is crucial. In response to the lack of research self-efficacy of many previously disadvantaged individuals, the article examines how mentoring can enhance the research self-efficacy of mentees. The study is grounded in the self-efficacy theory (SET) – an aspect of the social cognitive theory (SCT). Insights were gained from an in-depth study of SCT, SET and mentoring, and from a completed mentoring project. This led to the formulation of three basi...

  7. Efforts to Bridge the Gap between Research and Practice in Social Work: Precedents and Prospects: Keynote Address at the Bridging the Gap Symposium

    Science.gov (United States)

    Rubin, Allen

    2015-01-01

    This keynote address discusses previous and ongoing efforts to reduce the persistent gap between research and practice in social work and offers recommendations for further bridging that gap. Key among those recommendations is the need to conduct descriptive outcome studies of efforts to adapt research-supported interventions in everyday practice…

  8. Mentoring to develop research selfefficacy, with particular reference to previously disadvantaged individuals

    Directory of Open Access Journals (Sweden)

    S. Schulze

    2010-07-01

    Full Text Available The development of inexperienced researchers is crucial. In response to the lack of research self-efficacy of many previously disadvantaged individuals, the article examines how mentoring can enhance the research self-efficacy of mentees. The study is grounded in the self-efficacy theory (SET – an aspect of the social cognitive theory (SCT. Insights were gained from an in-depth study of SCT, SET and mentoring, and from a completed mentoring project. This led to the formulation of three basic principles. Firstly, institutions need to provide supportive environmental conditions that facilitate research selfefficacy. This implies a supportive and efficient collective system. The possible effects of performance ratings and reward systems at the institution also need to be considered. Secondly, mentoring needs to create opportunities for young researchers to experience successful learning as a result of appropriate action. To this end, mentees need to be involved in actual research projects in small groups. At the same time the mentor needs to facilitate skills development by coaching and encouragement. Thirdly, mentors need to encourage mentees to believe in their ability to successfully complete research projects. This implies encouraging positive emotional states, stimulating self-reflection and self-comparison with others in the group, giving positive evaluative feedback and being an intentional role model.

  9. Identification of gaps in the national research effort related to radioactive waste management

    International Nuclear Information System (INIS)

    Thorne, M.C.; Plews, M.; Kane, P.

    1987-08-01

    Based on papers submitted to the Government's Radioactivity Research and Environmental Monitoring Committee (RadREM), this report presents a consolidated summary of perceived research requirements for 1988/89 and a comparison with the research proposed for that period. On this basis, discussion is included of gaps in the national research effort to 1989, duplication of research plans and areas where better co-ordination or funding of research might be appropriate. (author)

  10. Group-Effort Applied Research (GEAR): Expanding Opportunities for Undergraduate Research Through Original, Class-Based Research Projects

    Science.gov (United States)

    Moore, Sean D.; Teter, Ken

    2014-01-01

    Undergraduate research clearly enriches the educational development of participating students, but these experiences are limited by the inherent inefficiency of the standard one student - one mentor model for undergraduate research. Group-Effort Applied Research (GEAR) was developed as a strategy to provide substantial numbers of undergraduates with meaningful research experiences. The GEAR curriculum delivers concept-driven lecture material and provides hands-on training in the context of an active research project from the instructor's lab. Because GEAR is structured as a class, participating students benefit from intensive, supervised research training that involves a built-in network of peer support and abundant contact with faculty mentors. The class format also ensures a relatively standardized and consistent research experience. Furthermore, meaningful progress toward a research objective can be achieved more readily with GEAR than with the traditional one student - one mentor model of undergraduate research because sporadic mistakes by individuals in the class are overshadowed by the successes of the group as a whole. Three separate GEAR classes involving three distinct research projects have been offered to date. In this paper, we provide an overview of the GEAR format and review some of the recurring themes for GEAR instruction. We propose GEAR can serve as a template to expand student opportunities for life science research without sacrificing the quality of the mentored research experience. PMID:24898007

  11. A Semantic Web-Based Methodology for Describing Scientific Research Efforts

    Science.gov (United States)

    Gandara, Aida

    2013-01-01

    Scientists produce research resources that are useful to future research and innovative efforts. In a typical scientific scenario, the results created by a collaborative team often include numerous artifacts, observations and relationships relevant to research findings, such as programs that generate data, parameters that impact outputs, workflows…

  12. Do family physicians retrieve synopses of clinical research previously read as email alerts?

    Science.gov (United States)

    Grad, Roland; Pluye, Pierre; Johnson-Lafleur, Janique; Granikov, Vera; Shulha, Michael; Bartlett, Gillian; Marlow, Bernard

    2011-11-30

    A synopsis of new clinical research highlights important aspects of one study in a brief structured format. When delivered as email alerts, synopses enable clinicians to become aware of new developments relevant for practice. Once read, a synopsis can become a known item of clinical information. In time-pressured situations, remembering a known item may facilitate information retrieval by the clinician. However, exactly how synopses first delivered as email alerts influence retrieval at some later time is not known. We examined searches for clinical information in which a synopsis previously read as an email alert was retrieved (defined as a dyad). Our study objectives were to (1) examine whether family physicians retrieved synopses they previously read as email alerts and then to (2) explore whether family physicians purposefully retrieved these synopses. We conducted a mixed-methods study in which a qualitative multiple case study explored the retrieval of email alerts within a prospective longitudinal cohort of practicing family physicians. Reading of research-based synopses was tracked in two contexts: (1) push, meaning to read on email and (2) pull, meaning to read after retrieval from one electronic knowledge resource. Dyads, defined as synopses first read as email alerts and subsequently retrieved in a search of a knowledge resource, were prospectively identified. Participants were interviewed about all of their dyads. Outcomes were the total number of dyads and their type. Over a period of 341 days, 194 unique synopses delivered to 41 participants resulted in 4937 synopsis readings. In all, 1205 synopses were retrieved over an average of 320 days. Of the 1205 retrieved synopses, 21 (1.7%) were dyads made by 17 family physicians. Of the 1205 retrieved synopses, 6 (0.5%) were known item type dyads. However, dyads also occurred serendipitously. In the single knowledge resource we studied, email alerts containing research-based synopses were rarely retrieved

  13. Status of DOE efforts to renew acceptance of foreign research reactor spent nuclear fuel

    Energy Technology Data Exchange (ETDEWEB)

    Head, C.R.

    1997-08-01

    This presentation summarizes the efforts being made by the Department of Energy to renew acceptance of spent nuclear fuel shipments from foreign research reactors. The author reviews the actions undertaken in this process in a fairly chronological manner, through the present time, as well as the development of an environmental impact statement to support the proposed actions.

  14. [Effort-reward imbalance at work and depression: current research evidence].

    Science.gov (United States)

    Siegrist, J

    2013-01-01

    In view of highly prevalent stressful conditions in modern working life, in particular increasing work pressure and job insecurity, it is of interest to know whether specific constellations of an adverse psychosocial work environment increase the risk of depressive disorder among employed people. This contribution gives a short overview of current research evidence based on an internationally established work stress model of effort-reward imbalance. Taken together, results from seven prospective epidemiological investigations demonstrate a two-fold elevated relative risk of incident depressive disorder over a mean observation period of 2.7 years among exposed versus non-exposed employees. Additional findings from experimental and quasi-experimental studies point to robust associations of effort-reward imbalance at work with proinflammatory cytokines and markers of reduced immune competence. These latter markers may indicate potential psychobiological pathways. In conclusion, incorporating this new knowledge into medical treatment and preventive efforts seems well justified.

  15. A Global Review of Sustainable Construction Project Financing: Policies, Practices, and Research Efforts

    Directory of Open Access Journals (Sweden)

    Ming Shan

    2017-12-01

    Full Text Available Despite the increasing investment in sustainable development over the past decade, a systematic review of sustainable construction project financing is lacking. The objectives of this paper are to conduct a systematic review to examine the policies, practices, and research efforts in the area of sustainable construction project financing, and to explore the potential opportunities for the future research. To achieve these goals, this paper first reviewed the sustainable construction project financing practices implemented by four representative developed economies including the United Kingdom, the United States, Singapore, and Australia. Then, this paper reviewed the efforts and initiatives launched by three international organizations including the United Nations, the Organization for Economic Co-operation and Development, and International Finance Corporation. After that, this paper reviewed the research efforts of sustainable construction project financing published in peer-review journals and books. This paper identified four major research themes within this area, which are the review of financial stakeholders and market of sustainable construction, benefits and barriers to sustainable construction project financing, financial vehicles for sustainable construction projects, innovative models and mechanisms for sustainable construction project financing. Additionally, this paper revealed five directions for the future research of sustainable construction project financing, which are the identification of financial issues in sustainable construction projects, the investigation of financial vehicles for sustainable construction projects in terms of their strengths, limitations, and performances, the examination of critical drivers for implementing sustainable construction project financing, the development of a knowledge-based decision support system for implementing sustainable construction financing, and the development of best practices for

  16. The development of nuclear power and the research effort in the Community

    International Nuclear Information System (INIS)

    Davies, D.H.

    1986-01-01

    The development of nuclear power in the European Community up to the present time is reviewed in the light of the 1973 oil crisis. The European Community nuclear energy policy and strategy are described, as well as the future objectives for the development of nuclear power in Europe. The research effort in the Community, concerning energy resources, and including nuclear fission energy, is outlined. Research and development (R and D) work in the field of radioactive waste management is reviewed. Also some achievements of the twelve year Plan of Action, and of the multiannual R and D programmes are presented. (U.K.)

  17. On-power fuelling machine of Dhruva research reactor: An indigenous effort (Paper No. 043)

    International Nuclear Information System (INIS)

    Rao, T.K.; Andhansare, M.G.

    1987-02-01

    On-power fuelling machine of Dhruva Research Reactor has been indigenously designed, manufactured, installed and commissioned. This is being used for fuelling of Dhruva Research reactor regularly since June 1985. This paper deals with the developmental efforts made during design and manufacture for meeting the functional requirements of the fuelling machine. This paper also highlights the special features of the components like servo valves, hydraulic motors, S.S. bellows, bearings, roller chains, solenoid valves etc. needed for reliable operation and maintenance of the fuelling machine whose down time should be minimum to achieve maximum reactor availability. (author). 17 figs

  18. Recent research efforts in the area of biotechnology for fuels and chemicals: Poster session papers

    Energy Technology Data Exchange (ETDEWEB)

    Antonopoulos, A.A. [Argonne National Lab., IL (United States); Grohmann, K. [US Citrus and Subtropical Products Lab., Winter Haven, FL (United States)

    1992-09-01

    This report presents research presented at the poster session of the Symposium covering a wide spectrum of current biotechnological research activities. Research focused mostly on ethanol production and methane generation from biomass material via microbial processing, as well as on enhanced hydrogen yield from algae. Several of the posters dealt with the pretreatment of cellulosic materials, and enzyme production/characterization, while a good number of papers displayed research efforts on bioremediation, photosynthesis, production of various useful chemicals from biomass by bioprocessing, and on other miscellaneous subjects. One of the papers treated a very interesting topic of cellulose-cellulase complexes. Many of the poster papers are included in this volume, and a synopsis of all the poster/papers presented is the subject of this article.

  19. Recent research efforts in the area of biotechnology for fuels and chemicals: Poster session papers

    Energy Technology Data Exchange (ETDEWEB)

    Antonopoulos, A.A. (Argonne National Lab., IL (United States)); Grohmann, K. (US Citrus and Subtropical Products Lab., Winter Haven, FL (United States))

    1992-01-01

    This report presents research presented at the poster session of the Symposium covering a wide spectrum of current biotechnological research activities. Research focused mostly on ethanol production and methane generation from biomass material via microbial processing, as well as on enhanced hydrogen yield from algae. Several of the posters dealt with the pretreatment of cellulosic materials, and enzyme production/characterization, while a good number of papers displayed research efforts on bioremediation, photosynthesis, production of various useful chemicals from biomass by bioprocessing, and on other miscellaneous subjects. One of the papers treated a very interesting topic of cellulose-cellulase complexes. Many of the poster papers are included in this volume, and a synopsis of all the poster/papers presented is the subject of this article.

  20. Integrating qualitative research methods into care improvement efforts within a learning health system: addressing antibiotic overuse.

    Science.gov (United States)

    Munoz-Plaza, Corrine E; Parry, Carla; Hahn, Erin E; Tang, Tania; Nguyen, Huong Q; Gould, Michael K; Kanter, Michael H; Sharp, Adam L

    2016-08-15

    Despite reports advocating for integration of research into healthcare delivery, scant literature exists describing how this can be accomplished. Examples highlighting application of qualitative research methods embedded into a healthcare system are particularly needed. This article describes the process and value of embedding qualitative research as the second phase of an explanatory, sequential, mixed methods study to improve antibiotic stewardship for acute sinusitis. Purposive sampling of providers for in-depth interviews improved understanding of unwarranted antibiotic prescribing and elicited stakeholder recommendations for improvement. Qualitative data collection, transcription and constant comparative analyses occurred iteratively. Emerging themes and sub-themes identified primary drivers of unwarranted antibiotic prescribing patterns and recommendations for improving practice. These findings informed the design of a health system intervention to improve antibiotic stewardship for acute sinusitis. Core components of the intervention are also described. Qualitative research can be effectively applied in learning healthcare systems to elucidate quantitative results and inform improvement efforts.

  1. Applied and fundamental plankton research would benefit from more joint efforts

    DEFF Research Database (Denmark)

    Hansen, Benni Winding; Jepsen, Per Meyer; Drillet, Guillaume

    2017-01-01

    Increased collaboration and communication is needed between the planktologists engaged in marine ecological research and those working with industrial applications. Lessening the dichotomy between “basic” and “applied” sciences will lead to increase scientific advances in both fields. Thanks...... to dedicated research efforts, industrial production of rotifers, Artemia and, more recently, copepods as live feed for fish hatcheries is established. Yet, there are still many biological and technical challenges to be tackled for optimizing production. Some of these challenges could be eliminated faster...... examples from research carried out to support aquaculture production of the cosmopolitan calanoid copepod Acartia tonsa. We argue that research questions are often answered using similar experimental approaches and quality standards; and that scientists working across different fields would gain by more...

  2. Progress in indoor radon measurement. Review of previous research (July 1981-February 1985)

    International Nuclear Information System (INIS)

    1985-01-01

    Research progress in the following areas is reported: (1) scintillation cell development and applications, (2) charcoal adsorption development and applications; (3) surveys with Terradex detectors; (4) radon carcinogenesis epidemiology; (5) large scale surveys of radon concentrations in randomly selected houses; (6) ventilation rate studies; (7) soil studies; (8) diffusion of radon through materials other than soil; and (9) test house studies

  3. Understanding Infants' and Children's Social Learning about Foods: Previous Research and New Prospects

    Science.gov (United States)

    Shutts, Kristin; Kinzler, Katherine D.; DeJesus, Jasmine M.

    2013-01-01

    Developmental psychologists have devoted significant attention to investigating how children learn from others' actions, emotions, and testimony. Yet most of this research has examined children's socially guided learning about artifacts. The present article focuses on a domain that has received limited attention from those interested in the…

  4. Analysis of current research addressing complementary use of life-cycle assessment and risk assessment for engineered nanomaterials: have lessons been learned from previous experience with chemicals?

    International Nuclear Information System (INIS)

    Grieger, Khara D.; Laurent, Alexis; Miseljic, Mirko; Christensen, Frans; Baun, Anders; Olsen, Stig I.

    2012-01-01

    While it is generally agreed that successful strategies to address the health and environmental impacts of engineered nanomaterials (NM) should consider the well-established frameworks for conducting life-cycle assessment (LCA) and risk assessment (RA), scientific research, and specific guidance on how to practically apply these methods are still very much under development. This paper evaluates how research efforts have applied LCA and RA together for NM, particularly reflecting on previous experiences with applying these methods to chemicals. Through a literature review and a separate analysis of research focused on applying LCA and RA together for NM, it appears that current research efforts have taken into account some key “lessons learned” from previous experience with chemicals while many key challenges remain for practically applying these methods to NM. We identified two main approaches for using these methods together for NM: “LC-based RA” (traditional RA applied in a life-cycle perspective) and “RA-complemented LCA” (conventional LCA supplemented by RA in specific life-cycle steps). Hence, the latter is the only identified approach which genuinely combines LC- and RA-based methods for NM-risk research efforts to date as the former is rather a continuation of normal RA according to standard assessment procedures (e.g., REACH). Both these approaches along with recommendations for using LCA and RA together for NM are similar to those made previously for chemicals, and thus, there does not appear to be much progress made specific for NM. We have identified one issue in particular that may be specific for NM when applying LCA and RA at this time: the need to establish proper dose metrics within both methods.

  5. Understanding infants' and children's social learning about foods: previous research and new prospects.

    Science.gov (United States)

    Shutts, Kristin; Kinzler, Katherine D; DeJesus, Jasmine M

    2013-03-01

    Developmental psychologists have devoted significant attention to investigating how children learn from others' actions, emotions, and testimony. Yet most of this research has examined children's socially guided learning about artifacts. The present article focuses on a domain that has received limited attention from those interested in the development of social cognition: food. We begin by reviewing the available literature on infants' and children's development in the food domain and identify situations in which children evidence both successes and failures in their interactions with foods. We focus specifically on the role that other people play in guiding what children eat and argue that understanding patterns of successes and failures in the food domain requires an appreciation of eating as a social phenomenon. We next propose a series of questions for future research and suggest that examining food selection as a social phenomenon can shed light on mechanisms underlying children's learning from others and provide ideas for promoting healthy social relationships and eating behaviors early in development.

  6. Research and development efforts in the implementation of nuclear power programme in Indonesia

    International Nuclear Information System (INIS)

    Suhaemi, T.

    1986-04-01

    Research and development efforts in the implementation of nuclear power programme in Indonesia are presented. According to Indonesia Law, the National Atomic Energy Agency (BATAN) is an official body which is reponsible for all aspects of nuclear development. In implementing the nuclear power, BATAN together with the State Electricity Corporation (PLN) have pioneered the introduction of nuclear power plant in Indonesia by carrying out various activities, studies, seminars, workshops and report writings. A nuclear power planning study was carried out jointly with the International Atomic Energy Agency. The feasibility studies were also carried out by NIRA, an Italian consultant firm in cooperation with BATAN and PLN. To improve research and development, BATAN has established 5 research nuclear centres which function as centres of basic and applied research, isotope and radiation application, standardization and calibration and uranium exploration. Nowadays BATAN is constructing a sophisticated and multidisciplinary complex at Serpong near Jakarta. It is hoped that the participation of the national industry can be synchronized to the construction of the first nuclear power in Indonesia. To endorse the movement towards the industrial and technological future, the National Centre for Research, Science and Technology (known as PUSPITEK) has been established. There will be 12 different laboratories providing facilities for research and development of all aspects of technology. For training manpower, BATAN has established the Education and Training Centre (PUSDIKLAT). BATAN has also collaborated with universities, such as Gadjahmada University in Yogyakarta, in establishing Nuclear Engineering Division in the School of Engineering. 6 refs, 3 figs

  7. A Review of Previous Research in Direct Energy Conversion Fission Reactors

    International Nuclear Information System (INIS)

    DUONG, HENRY; POLANSKY, GARY F.; SANDERS, THOMAS L.; SIEGEL, MALCOLM D.

    1999-01-01

    From the earliest days of power reactor development, direct energy conversion was an obvious choice to produce high efficiency electric power generation. Directly capturing the energy of the fission fragments produced during nuclear fission avoids the intermediate conversion to thermal energy and the efficiency limitations of classical thermodynamics. Efficiencies of more than 80% are possible, independent of operational temperature. Direct energy conversion fission reactors would possess a number of unique characteristics that would make them very attractive for commercial power generation. These reactors would be modular in design with integral power conversion and operate at low pressures and temperatures. They would operate at high efficiency and produce power well suited for long distance transmission. They would feature large safety margins and passively safe design. Ideally suited to production by advanced manufacturing techniques, direct energy conversion fission reactors could be produced more economically than conventional reactor designs. The history of direct energy conversion can be considered as dating back to 1913 when Moseleyl demonstrated that charged particle emission could be used to buildup a voltage. Soon after the successful operation of a nuclear reactor, E.P. Wigner suggested the use of fission fragments for direct energy conversion. Over a decade after Wigner's suggestion, the first theoretical treatment of the conversion of fission fragment kinetic energy into electrical potential appeared in the literature. Over the ten years that followed, a number of researchers investigated various aspects of fission fragment direct energy conversion. Experiments were performed that validated the basic physics of the concept, but a variety of technical challenges limited the efficiencies that were achieved. Most research in direct energy conversion ceased in the US by the late 1960s. Sporadic interest in the concept appears in the literature until this

  8. Transcranial magnetic stimulation in developmental stuttering: Relations with previous neurophysiological research and future perspectives.

    Science.gov (United States)

    Busan, P; Battaglini, P P; Sommer, M

    2017-06-01

    Developmental stuttering (DS) is a disruption of the rhythm of speech, and affected people may be unable to execute fluent voluntary speech. There are still questions about the exact causes of DS. Evidence suggests there are differences in the structure and functioning of motor systems used for preparing, executing, and controlling motor acts, especially when they are speech related. Much research has been obtained using neuroimaging methods, ranging from functional magnetic resonance to diffusion tensor imaging and electroencephalography/magnetoencephalography. Studies using transcranial magnetic stimulation (TMS) in DS have been uncommon until recently. This is surprising considering the relationship between the functionality of the motor system and DS, and the wide use of TMS in motor-related disturbances such as Parkinson's Disease, Tourette's Syndrome, and dystonia. Consequently, TMS could shed further light on motor aspects of DS. The present work aims to investigate the use of TMS for understanding DS neural mechanisms by reviewing TMS papers in the DS field. Until now, TMS has contributed to the understanding of the excitatory/inhibitory ratio of DS motor functioning, also helping to better understand and critically review evidence about stuttering mechanisms obtained from different techniques, which allowed the investigation of cortico-basal-thalamo-cortical and white matter/connection dysfunctions. Copyright © 2017 International Federation of Clinical Neurophysiology. Published by Elsevier B.V. All rights reserved.

  9. Collaborative research efforts and related activities of the Office of Rare Diseases Research at the USA National Institutes of Health

    Directory of Open Access Journals (Sweden)

    Stephen C. Groft

    2009-12-01

    Full Text Available

    Introduction: Rare diseases present unique challenges to meet the numerous and varied needs of the rare diseases community and it is required to identify and address these needs. Significant financial and personnel resources are required to address these needs identified. The Office of Rare Diseases Research (ORDR at the USA National Institutes of Health (NIH has attempted to meet many of these needs in collaborative efforts with the research Institutes and Centers of NIH and other partners in the private and public sectors in the USA and around the world. Several of the activities of the NIH and the ORDR are presented as possible collaborative efforts available to research investigators and include the Rare Diseases Clinical Research Network, the Bench-to-Bedside research program at NIH, the Genetic and Rare Diseases Information center, the genetic test development program, and the information on clinical research studies made available through Clinical trials.gov. The value of an appropriate family medical history is discussed as are the provisions of the Genetic Information Non-Discrimination Act of 2008 (GINA. Definitions of rare or orphan diseases vary from country to country and may cause some confusion to the rare diseases community.

    Conclusions: Rare diseases are not limited by geographical or historical boundaries and global partnerships of the rare diseases community are experiencing rapid expansion to assist in the development of orphan products for the prevention, diagnosis and treatment of rare diseases and conditions. The unmet needs of the rare diseases community require additional innovative research and educational programs to reach the extensive global populations affected by the thousands of different rare diseases including activities with the National Organization for Rare Disorders and the Genetic Alliance.

  10. Efforts onto nuclear research and development such as new reactor and so forth

    International Nuclear Information System (INIS)

    Onishi, Tuneji

    2000-01-01

    The Japan Atomic Power Co. which is one of specified business company on nuclear power generation, has carried out construction and operation of power plants with different types of reactor such as boiling light water reactor (BWR), pressurized light water rector (PWR), and so forth. And, by actively using technical powers and experiences accumulated before then, additional construction of a new power unit, and researches and developments on a simplified light water reactor, a future type rector, and a high breeder proof reactor have been made some efforts. Here were introduced some outlines on development of an improved type PWR, development of a new type reactor for example, deep embedded plant), future type reactor (for example, revolutionary middle and small type reactor, simplified PWR, and simplified BWR), a fast breeder reactor, and a reactor building suitable for a ship shell structure. (G.K.)

  11. Qualitative Research Methods to Advance Research on Health Inequities among Previously Incarcerated Women Living with HIV in Alabama

    Science.gov (United States)

    Sprague, Courtenay; Scanlon, Michael L.; Pantalone, David W.

    2017-01-01

    Justice-involved HIV-positive women have poor health outcomes that constitute health inequities. Researchers have yet to embrace the range of qualitative methods to elucidate how psychosocial histories are connected to pathways of vulnerability to HIV and incarceration for this key population. We used life course narratives and…

  12. Analysis of current research addressing complementary use of life-cycle assessment and risk assessment for engineered nanomaterials: have lessons been learned from previous experience with chemicals?

    DEFF Research Database (Denmark)

    Grieger, Khara Deanne; Laurent, Alexis; Miseljic, Mirko

    2012-01-01

    of research focused on applying LCA and RA together for NM, it appears that current research efforts have taken into account some key ‘‘lessons learned’’ from previous experience with chemicals while many key challenges remain for practically applying these methods to NM. We identified two main approaches...... for using these methods together for NM: ‘‘LC-based RA’’ (traditional RA applied in a life-cycle perspective) and ‘‘RA-complemented LCA’’ (conventional LCA supplemented by RA in specific life-cycle steps). Hence, the latter is the only identified approach which genuinely combines LC- and RA-based methods......While it is generally agreed that successful strategies to address the health and environmental impacts of engineered nanomaterials (NM) should consider the well-established frameworks for conducting life-cycle assessment (LCA) and risk assessment (RA), scientific research, and specific guidance...

  13. Dopamine, Effort-Based Choice, and Behavioral Economics: Basic and Translational Research.

    Science.gov (United States)

    Salamone, John D; Correa, Merce; Yang, Jen-Hau; Rotolo, Renee; Presby, Rose

    2018-01-01

    Operant behavior is not only regulated by factors related to the quality or quantity of reinforcement, but also by the work requirements inherent in performing instrumental actions. Moreover, organisms often make effort-related decisions involving economic choices such as cost/benefit analyses. Effort-based decision making is studied using behavioral procedures that offer choices between high-effort options leading to relatively preferred reinforcers vs. low effort/low reward choices. Several neural systems, including the mesolimbic dopamine (DA) system and other brain circuits, are involved in regulating effort-related aspects of motivation. Considerable evidence indicates that mesolimbic DA transmission exerts a bi-directional control over exertion of effort on instrumental behavior tasks. Interference with DA transmission produces a low-effort bias in animals tested on effort-based choice tasks, while increasing DA transmission with drugs such as DA transport blockers tends to enhance selection of high-effort options. The results from these pharmacology studies are corroborated by the findings from recent articles using optogenetic, chemogenetic and physiological techniques. In addition to providing important information about the neural regulation of motivated behavior, effort-based choice tasks are useful for developing animal models of some of the motivational symptoms that are seen in people with various psychiatric and neurological disorders (e.g., depression, schizophrenia, Parkinson's disease). Studies of effort-based decision making may ultimately contribute to the development of novel drug treatments for motivational dysfunction.

  14. Dopamine, Effort-Based Choice, and Behavioral Economics: Basic and Translational Research

    Directory of Open Access Journals (Sweden)

    John D. Salamone

    2018-03-01

    Full Text Available Operant behavior is not only regulated by factors related to the quality or quantity of reinforcement, but also by the work requirements inherent in performing instrumental actions. Moreover, organisms often make effort-related decisions involving economic choices such as cost/benefit analyses. Effort-based decision making is studied using behavioral procedures that offer choices between high-effort options leading to relatively preferred reinforcers vs. low effort/low reward choices. Several neural systems, including the mesolimbic dopamine (DA system and other brain circuits, are involved in regulating effort-related aspects of motivation. Considerable evidence indicates that mesolimbic DA transmission exerts a bi-directional control over exertion of effort on instrumental behavior tasks. Interference with DA transmission produces a low-effort bias in animals tested on effort-based choice tasks, while increasing DA transmission with drugs such as DA transport blockers tends to enhance selection of high-effort options. The results from these pharmacology studies are corroborated by the findings from recent articles using optogenetic, chemogenetic and physiological techniques. In addition to providing important information about the neural regulation of motivated behavior, effort-based choice tasks are useful for developing animal models of some of the motivational symptoms that are seen in people with various psychiatric and neurological disorders (e.g., depression, schizophrenia, Parkinson’s disease. Studies of effort-based decision making may ultimately contribute to the development of novel drug treatments for motivational dysfunction.

  15. Leopard (Panthera pardus status, distribution, and the research efforts across its range

    Directory of Open Access Journals (Sweden)

    Andrew P. Jacobson

    2016-05-01

    Full Text Available The leopard’s (Panthera pardus broad geographic range, remarkable adaptability, and secretive nature have contributed to a misconception that this species might not be severely threatened across its range. We find that not only are several subspecies and regional populations critically endangered but also the overall range loss is greater than the average for terrestrial large carnivores. To assess the leopard’s status, we compile 6,000 records at 2,500 locations from over 1,300 sources on its historic (post 1750 and current distribution. We map the species across Africa and Asia, delineating areas where the species is confirmed present, is possibly present, is possibly extinct or is almost certainly extinct. The leopard now occupies 25–37% of its historic range, but this obscures important differences between subspecies. Of the nine recognized subspecies, three (P. p. pardus, fusca, and saxicolor account for 97% of the leopard’s extant range while another three (P. p. orientalis, nimr, and japonensis have each lost as much as 98% of their historic range. Isolation, small patch sizes, and few remaining patches further threaten the six subspecies that each have less than 100,000 km2 of extant range. Approximately 17% of extant leopard range is protected, although some endangered subspecies have far less. We found that while leopard research was increasing, research effort was primarily on the subspecies with the most remaining range whereas subspecies that are most in need of urgent attention were neglected.

  16. China's Efforts on Management, Surveillance, and Research of Noncommunicable Diseases: NCD Scorecard Project.

    Science.gov (United States)

    Zhu, Xiao-Lei; Luo, Jie-Si; Zhang, Xiao-Chang; Zhai, Yi; Wu, Jing

    where China had the greatest need for improvement included increasing taxes on tobacco and addressing the needs of the population older than age 70 dying from major NCDs. In China the burden of disease of NCDs and disabilities remains serious, although China has put significant efforts into its governance and surveillance and research. To improve, further action is needed on reducing tobacco consumption, increasing investment in the national health budget, and increasing the focus on system construction. Copyright © 2017 Icahn School of Medicine at Mount Sinai. Published by Elsevier Inc. All rights reserved.

  17. 76 FR 8788 - National Nanotechnology Coordination Office; Bridging NanoEHS Research Efforts: A Joint US-EU...

    Science.gov (United States)

    2011-02-15

    ... OFFICE OF SCIENCE AND TECHNOLOGY POLICY National Nanotechnology Coordination Office; Bridging NanoEHS Research Efforts: A Joint US-EU Workshop: Public Meeting AGENCY: National Nanotechnology Coordination Office, STPO. ACTION: Notice of public meeting. SUMMARY: The National Nanotechnology Coordination...

  18. Recent Efforts in Communications Research and Technology at the Glenn Research Center in Support of NASA's Mission

    Science.gov (United States)

    Miranda, Felix A.

    2015-01-01

    As it has done in the past, NASA is currently engaged in furthering the frontiers of space and planetary exploration. The effectiveness in gathering the desired science data in the amount and quality required to perform this pioneering work relies heavily on the communications capabilities of the spacecraft and space platforms being considered to enable future missions. Accordingly, the continuous improvement and development of radiofrequency and optical communications systems are fundamental to prevent communications to become the limiting factor for space explorations. This presentation will discuss some of the research and technology development efforts currently underway at the NASA Glenn Research Center in the radio frequency (RF) and Optical Communications. Examples of work conducted in-house and also in collaboration with academia, industry, and other government agencies (OGA) in areas such as antenna technology, power amplifiers, radio frequency (RF) wave propagation through Earths atmosphere, ultra-sensitive receivers, thin films ferroelectric-based tunable components, among others, will be presented. In addition, the role of these and other related RF technologies in enabling the NASA next generation space communications architecture will be also discussed.

  19. Maximizing industry benefit through cooperation between federal, state and private-sector floricultural research efforts

    Science.gov (United States)

    he USDA-ARS Greenhouse Production Research Group was established to provide a federally funded research emphasis on greenhouse crop production. It has focused on broad production issues (nutrition, water management, and energy conservation) by coordinating research between in-house researchers, Uni...

  20. Ecuador's Efforts to Raise Its Research Profile: The Prometeo Program Case Study

    Science.gov (United States)

    Van Hoof, Hubert B.

    2015-01-01

    Ecuador's government understands that capable research universities can help in solving the country's pressing socio-economic problems. However, research capabilities and research productivity in its national universities have historically been low, as professors primarily teach and often do not have the inclination, the ability, or the time to do…

  1. Research and development efforts relative to superconducting materials. Final report. [Nb/sub 3/Sn tapes

    Energy Technology Data Exchange (ETDEWEB)

    Adam, E; Beishcher, P; Marancik, W; Lucariello, R; Young, M

    1976-04-01

    Three processes for the production of low-loss superconducting tapes of Nb/sub 3/Sn were investigated. They are the rolled-bronze process, the electron beam (EB) bronze deposition process, and the high-rate sputtering process. Shortly after the start of the investigation, effort on the last two processes was suspended because the process-development time that would be needed to arrive at a suitable transmission-line tape appeared most likely to be the shortest with the rolled-bronze process. Long lengths of Nb/sub 3/Sn tapes were prepared by the rolled-bronze process from extruded and rolled bronze-clad niobium billets. Tapes were stabilized by removing the bronze layer after reaction and then coating the exposed Nb/sub 3/Sn with high-purity copper by EB evaporation. Several meters of high quality Nb/sub 3/Sn tapes were produced by the rolled-bronze process. Even when the tapes were stabilized with copper, the losses were as low as 1.8 ..mu..W/cm/sup 2/ at 4.2 K and a surface current density of 500 rms A/cm. Despite early curtailment of the effort on the EB bronze-deposition process, short samples of Nb/sub 3/Sn tapes were produced.

  2. SEAS-ERA: An overarching effort to coordinate marine research policies across Europe

    OpenAIRE

    Morales-Nin, Beatriz; Albaigés Riera, Joan

    2015-01-01

    © 2015 Elsevier Ltd. The aim of the SEAS-ERA initiative (2010-2014), developed within the European Union Framework Programme (EU FPVII) (contract 249552), was to coordinate the structure of national and regional marine and maritime research programs to empower and strengthen marine research all across Europe. A major goal was the development and implementation of common research strategies and programs related to European seas basins. To achieve this goal, SEAS-ERA was applied at two differen...

  3. Co-ordinated Interdisciplinary Efforts on Research in Animal Production and Health

    Directory of Open Access Journals (Sweden)

    Houe Hans

    2003-03-01

    Full Text Available The objectives are to review results and experiences from interdisciplinary research projects in Research Centre for the Management of Animal Production and Health (CEPROS concerning scientific content, organisation, and collaboration. The Centre has been founded as a result of an agreement between four institutions: the Danish Institute of Agricultural Sciences (DIAS, the Danish Veterinary Laboratory (DVL, the Danish Veterinary Institute for Virus Research (DVIV and The Royal Veterinary and Agricultural University (KVL. CEPROS is a "research centre without walls" and is physically located as an integrated part of the four institutions named above. The Centre has close collaboration with the industry. The superior goals of the Centre are to co-ordinate fundamental and applied research and simultaneously integrate the veterinary and the production oriented livestock research within animal health and welfare, taking into consideration the production economics and reduced use of medication. The assignment of the Centre is to initiate and carry out research, aiming to investigate the influence of breeding and production systems on animal health and welfare as well as on production and product quality. The Centre has since 1997 established 16 interdisciplinary research projects dealing with cattle, pigs, poultry, or mink. The scientific content can be divided into three research clusters: A. Management of animal production and health in production systems, B: Pathogenesis of production diseases, and C. Animal health economics. In Cluster A, the physical environments of production systems have been investigated, broader definitions of the concept health have been established and used in identification of risk factors. Cluster B has investigated physiological, immunological and genetic mechanisms behind development of production diseases and how to apply this knowledge in disease prevention. The cluster in animal health economics has developed decision

  4. Supporting Faculty Efforts to Obtain Research Funding: Successful Practices and Lessons Learned

    Science.gov (United States)

    Reiser, Robert A.; Moore, Alison L.; Bradley, Terra W.; Walker, Reddick; Zhao, Weinan

    2015-01-01

    Faculty members face increasing pressure to secure external research funding, and as a result, there is a critical need for professional development in this area. This paper describes a series of tools and services that have been designed and implemented by a College of Education Office of Research at a southeastern university in order to help…

  5. Why Feminism? How Feminist Methodologies Can Aid Our Efforts to ‘Give Back’ Through Research

    Directory of Open Access Journals (Sweden)

    Hekia Ellen Golden Bodwitch

    2014-07-01

    Full Text Available In this thematic section, the authors take a critical stance to the notion of giving back. They emphasize that giving back should be a model of solidarity and movement building, not charity. They push us to consider the ways in which the framework of giving back may actually reinforce hierarchical relationships between the researcher and the researched. In doing so, they offer new ways of thinking about the relationship between researchers and their communities of subjects. The strategies employed by these authors resonate with work from feminist activists and scholars whose approaches bring us alternative theories and methods through which to address the potentially dangerous effects of speaking for others through research. Examined alongside the giving back pieces in this section, these feminist contributions illuminate ways that we can give back by advancing the anti-oppression agendas of marginalized subjects through our research.

  6. Anatomy of an organizational change effort at the Lewis Research Center

    Science.gov (United States)

    Hawker, James R.; Dali, Richard S.

    1988-01-01

    By 1979, after a long decline following the end of the Apollo program, the Lewis Research Center found its very existence endangered because it was not doing the kind of research that could attract funding at the time. New management under Andrew J. Stofan applied a program of strategic planning, participative management, and consensus decision making. A corporate-cultural change was effected which enabled Lewis to commit itself to four fundable research and development projects. Morale-building and training programs which were essential to this change are described.

  7. Pan Eurasian EXperiment (PEEX) - towards a new multinational environment and climate research effort in Eurasia

    Science.gov (United States)

    Petäjä, Tuukka; Kulmala, Markku; Lappalainen, Hanna; Sipilä, Mikko; Sorvari, Sanna; Alekseychik, Pavel; Paramonov, Mikhail; Kerminen, Veli-Matti; Zilitinkevich, Sergej

    2013-04-01

    Boreal forests are a substantial source of greenhouse gases, biogenic volatile organic compounds (BVOCs) and natural aerosols, the critical atmospheric components related to climate change processes. A large fraction of boreal forests of the world is situated in Siberian region. Representative measurements of carbon dioxide (CO2) and methane (CH4) concentrations, BVOC emissions and aerosols production from Siberian are of special importance when estimating global budgets of climate change relevant factors. The scope of a new concept of the Pan Eurasian Experiment (PEEX) is to set up a process for planning of a large-scale, long-term, coordinated observations and modeling experiment in the Pan Eurasian region, especially to cover ground base, airborne and satellite observations together with global and regional models to find out different forcing and feedback mechanisms in the changing climate. University of Helsinki together with Finnish Meteorological institute are organizing the Pan-Eurasian Experiment and to gather all the European and Russian key players in the field of climate and Earth system science to plan the future research activities in the Pan-Eurasian region. In the European scale PEEX is part of the JPI Climate Fast Track Activity 1.3. "Changing cryosphere in the climate system - from observations to climate modeling". PEEX research topics are closely related the NordForsk's Top Research Initiative CRAICC - Cryosphere - atmosphere interaction in the changing Arctic climate. PEEX is also a central part of the ongoing the Finnish Cultural Foundation - Earth System modeling Working Group activity (2012-2013). PEEX scientific aims and future actions to develop Pan Eurasian research infrastructure can be linked to several EC and ESA funded activities aiming to develop next generation research infrastructures and data products: EU-FP7-ACTRIS-I3-project (Aerosols, Clouds, and Trace gases Research InfraStructure Network-project 2011-2015); ICOS a research

  8. Application of the partitive analytical forecasting (PAF) technique to the United States controlled thermonuclear research effort

    International Nuclear Information System (INIS)

    Nichols, S.P.

    1975-01-01

    The Partitive Analytical Forecasting (PAF) technique is applied to the overall long-term program plans for the Division of Controlled Thermonuclear Research (DCTR) of the United States Energy Research and Development Administration (ERDA). As part of the PAF technique, the Graphical Evaluation and Review Technique (GERTS) IIIZ computer code is used to perform simulations on a logic network describing the DCTR long-term program plan. Logic networks describing the tokamak, mirror, and theta-pinch developments are simulated individually and then together to form an overall DCTR program network. The results of the simulation of the overall network using various funding schemes and strategies are presented. An economic sensitivity analysis is provided for the tokamak logic networks. An analysis is also performed of the fusion-fission hybrid concept in the context of the present DCTR goals. The results mentioned above as well as the PAF technique itself are evaluated, and recommendations for further research are discussed

  9. Coordinated effort to advance genomes-to-phenomes through the integration of bioinformatics with aquaculture research

    Science.gov (United States)

    Aquaculture is the fastest growing food production system in the world. The research program at the USDA-ARS-SNARC strives to improve the efficiency and sustainability of warmwater U.S. aquaculture. SNARC scientists have impacted the catfish (#1 U.S. aquaculture industry), tilapia (#3) and hybrid st...

  10. Effectiveness and profile of the SIMRAC research effort in improving safety in gold and platinum sectors.

    CSIR Research Space (South Africa)

    Triebel, R

    2001-11-01

    Full Text Available . The research indicated SIMRAC as not a waste of time and money. General positives that have emerged are the strong stakeholder support for the intent of the organisation, the view that SIMPROSS, in providing a project management and administrative support...

  11. Untied Efforts: The Challenges for Improved Research, Extension and Education Linkages

    Science.gov (United States)

    Eneyew, Adugna

    2013-01-01

    Ethiopian agriculture is characterized by smallholders farming whose access to modern technology and basic education is very limited. Research, extension, education and farmers are the main pillars of agricultural knowledge systems and their effectiveness largely depends on strong linkage among each other. However, the existing…

  12. NREL-Led Research Effort Creates New Alloys, Phase Diagram | News | NREL

    Science.gov (United States)

    the next-generation semiconductors. A multi-institutional team led by NREL discovered a way to create to right) Stephan Lany, Aaron Holder, Paul Ndione, and Andriy Zakutayev. A multi-institutional team the breakthrough and took the idea from theory to reality. An Energy Frontier Research Center, which

  13. Research efforts on fuels, fuel models, and fire behavior in eastern hardwood forests

    Science.gov (United States)

    Thomas A. Waldrop; Lucy Brudnak; Ross J. Phillips; Patrick H. Brose

    2006-01-01

    Although fire was historically important to most eastern hardwood systems, its reintroduction by prescribed burning programs has been slow. As a result, less information is available on these systems to fire managers. Recent research and nationwide programs are beginning to produce usable products to predict fuel accumulation and fire behavior. We introduce some of...

  14. Conflict resolution efforts through stakeholder mapping in Labanan Research Forest, Berau, East Kalimantan, Indonesia

    Science.gov (United States)

    Wiati, C. B.; Indriyanti, S. Y.; Maharani, R.; Subarudi

    2018-04-01

    Conflict resolution in Labanan Research Forest (LRF) by the Dipterocarps Forest Ecosystem Research and Development Center (Balai Besar Penelitian dan Pengembangan Ekosistem Hutan Dipterokarpa – B2P2EHD) needs support from other parties that are also interested in such forest management. This paper aimed to presented conflict resolution in LRF through stakeholder mapping for its engagement. This research was conducted for seven months (June to December 2015) with interviews and literature study as its data collection. Collected data were analysed by a stakeholder analysis and matrix based on their interest and power levels. Two important findings were: (1) There are 19 parties having interests in the existence of LRF should be engaged; (2) Conflict resolution of LRF can be achieved: (a) ensuring key stakeholders which have high interest and high power level has same perception in existence and management of LRF, (b) establishing a partnership with primary stakeholders which have high interest and high power levels; (c) building partnerships between primary stakeholders which have high interest but low power levels, (d) building partnerships between key and secondary stakeholders which have low interest but high power levels and (e) gaining support from primary and secondary stakeholders which have low interest and low power levels. Stakeholder mapping is an important tool for tenure conflict resolution through mapping the power and interest of the conflicted parties and finding the proper parties to be approached.

  15. Collaboration in Arctic Research: Best Practices to Build and Sustain Successful Cross- and Trans-disciplinary Efforts

    Science.gov (United States)

    Wiggins, H. V.; Rich, R. H.

    2015-12-01

    The rapid physical and social changes currently underway in the Arctic - and changes in the way in which we study and manage the region -- require coordinated research efforts to improve our understanding of the Arctic's physical, biological, and social systems and the implications of change at many scales. At the same time, policy-makers and Arctic communities need decision-support tools and synthesized information to respond and adapt to the "new Arctic". There are enormous challenges, however, in collaboration among the disparate groups of people needed for such efforts. A carefully planned strategic approach is required to bridge the scientific disciplinary and organizational boundaries, foster cooperation between local communities and science programs, and effectively communicate between scientists and policy-makers. Efforts must draw on bodies of knowledge from project management, strategic planning, organizational development, and group dynamics. This poster presentation will discuss best practices of building and sustaining networks of people to catalyze successful cross-disciplinary activities. Specific examples and case studies - both successes and failures -- will be presented that draw on several projects at the Arctic Research Consortium of the U.S. (ARCUS; www.arcus.org), a nonprofit membership organization composed of universities and institutions that have a substantial commitment to research in the Arctic.

  16. Towards a community effort to identify ethical principles for research in hydrology

    Science.gov (United States)

    Montanari, Alberto

    2010-05-01

    The hydrological community in Europe is growing rapidly in both size and, more importantly, scientific relevance and integrity. The Hydrological Sciences (HS) Division of EGU actively is promoting the above development by identifying research targets, stimulating the involvement of young scientists and managing a scientific open access journal based on a public peer review process. The management of the Division itself and the organisation of the General Assembly are carried out transparently, with the aim to seek an improved involvement of top and young scientists, with a bottom up approach. I believe the HS community is animated by a strong enthusiasm which, however, is not adequately supported by economical funding. In my opinion this is a major problem which HS should consider and discuss. The relevance of the societal and environmental problems dealt with by hydrologists, in a professional way and with exceptional scientific skills, is without doubt and therefore the limited amount of funding is not justified in practice. In my opinion, in order to refine the structure of the HS community, and promote its visibility, we should formally identify HS ethical principles for research in environmental science. The principles should highlight the role of hydrology as well as the ethical and scientific solidity of the HS community. Establishing ethical principles is even more important in view of the transparent approach HS is adopting for reviewing and publishing contributions and in view of the increasing need to transparently prove how public funding for research is administered. Establishing ethical principles for hydrology is not a trivial task. Hydrology is characterised by a relevant uncertainty in data, models and parameters. Hydrology is also relying on a large variety of approaches, ranging from statistical to physically based. The purpose of this poster is to present a collection of ethical principles for scientific research presented by the literature and

  17. Using research data to impact consumer protection legislation: lessons learned from CITY100 dissemination efforts.

    Science.gov (United States)

    Hoerster, Katherine D; Mayer, Joni A

    2013-09-01

    The Correlates of Indoor Tanning in Youth (CITY100) project evaluated individual, built-environmental, and policy correlates of indoor tanning by adolescents in the 100 most populous US cities. After CITY100's completion, the research team obtained supplemental dissemination funding to strategically share data with stakeholders. The primary CITY100 dissemination message was to encourage state-level banning of indoor tanning among youth. We created a user-friendly website to broadly share the most relevant CITY100 data. Journalists were a primary target audience, as were health organizations that would be well positioned to advocate for legislative change. CITY100 data were used to pass the first US state law to ban indoor tanning among those under 18 (CA, USA), as well as in other legislative advocacy activities. This paper concludes with lessons learned from CITY100 dissemination activities that we hope will encourage more health researchers to proactively address policy implications of their data and to design relevant, effective dissemination strategies.

  18. Enhancing the research and publication efforts of health sciences librarians via an academic writing retreat.

    Science.gov (United States)

    Bullion, John W; Brower, Stewart M

    2017-10-01

    This case study describes the South Central Chapter of the Medical Library Association (SCC/MLA) initiative to develop an academic writing retreat for members who sought the necessary time and support to advance their research projects toward publication. SCC/MLA staged a dedicated writing retreat to coincide with the organization's 2012, 2013, and 2014 annual meetings. Each cohort met over two days to write and to workshop their peers' manuscripts. Organizers distributed an online survey one month after each retreat to evaluate attendees' perceptions. Three years' worth of writing retreats yielded fourteen peer-reviewed articles and one book chapter. Participants indicated that the retreat helped them meet or exceed their writing goals by offering protected time and a setting conducive to productivity. The format of the retreat is cost effective and easily adaptable for fellow professionals who wish to organize a formal event as a conference offering or simply support a writing group at their home institutions. In SCC/MLA, the retreat revitalized interest in writing and demystified the scholarly publication process.

  19. 78 FR 8490 - Notice of Intent To Request Revision of the Previously Requested Experimental Economic Research-A...

    Science.gov (United States)

    2013-02-06

    ... techniques, including laboratory and field techniques, exploratory interviews, pilot experiments and... be managed for research purposes only. Specific details regarding information handling will be...

  20. Reasons for placement of restorations on previously unrestored tooth surfaces by dentists in The Dental Practice-Based Research Network

    DEFF Research Database (Denmark)

    Nascimento, Marcelle M; Gordan, Valeria V; Qvist, Vibeke

    2010-01-01

    The authors conducted a study to identify and quantify the reasons used by dentists in The Dental Practice-Based Research Network (DPBRN) for placing restorations on unrestored permanent tooth surfaces and the dental materials they used in doing so....

  1. Childhood Obesity Declines Project: An Effort of the National Collaborative on Childhood Obesity Research to Explore Progress in Four Communities.

    Science.gov (United States)

    Kauh, Tina J; Dawkins-Lyn, Nicola; Dooyema, Carrie; Harris, Carole; Jernigan, Jan; Kettel Khan, Laura; Ottley, Phyllis; Young-Hyman, Deborah

    2018-03-01

    Recent findings show that national childhood obesity prevalence overall is improving among some age groups, but that disparities continue to persist, particularly among populations that have historically been at higher risk of obesity and overweight. Over the past several years, many jurisdictions at the city or county level across the nation have also reported declines. Little evaluation has focused on understanding the factors that influence the implementation of efforts to reduce childhood obesity rates. This article summarizes the rationale, aims, and overall design of the Childhood Obesity Declines Project (COBD), which was the first of its kind to systematically study and document the what, how, when, and where of community-based obesity strategies in four distinct communities across the nation. COBD was initiated by the National Collaborative on Childhood Obesity Research (NCCOR), was led by a subset of NCCOR advisors and a research team at ICF, and was guided by external advisors made up of researchers, decision makers, and other key stakeholders. The research team used an adapted version of the Systematic Screening and Assessment method to review and collect retrospective implementation data in four communities. COBD found that sites implemented strategies across the many levels and environments that impact children's well being (akin to the social-ecological framework), building a Culture of Health in their communities. COBD demonstrates how collaboratives of major funders with the support of other experts and key stakeholders, can help to accelerate progress in identifying and disseminating strategies that promote healthy eating and physical activity.

  2. Continued efforts to improve the robustness of the French Gen II PWRs with respect to the risk of severe accidents. Safety assessment and research activities

    International Nuclear Information System (INIS)

    Raimond, E.; Bonnet, J.M.; Generino, G.; Dubreuil, M.; Pichereau, F.; Van Dorsselaere, J.P.

    2012-01-01

    In the context of post Fukushima accident, the paper presents the continuous efforts performed in France to upgrade progressively the French Gen II pressurised water reactors safety features in order to face the risks of any severe accident. It reminds some decisions taken after the TMI2 and the Chernobyl accidents and describes the situation in France before the Fukushima accident: -) progress done on severe accident consequences analysis thanks to recent research activities, -) improvement of Gen II PWRs safety features, in relation with the periodic safety review process, -) definition of higher safety levels requirement directly linked to the protection of population in the framework of Gen II PWRs long term operation. The last part of the paper comments carefully how the Fukushima accident will interfere on all these previous efforts to increase the Gen II PWRs robustness. The Fukushima accident clearly highlights a need of additional efforts to identify possible cliff edge effect in case of beyond design events (especially external events). The definition of additional accident management procedures and means to secure a reactor (or a site) whatever the conditions will be a major consequence for the French NPPs. In a second step, some complements on the existing defense-in-depth approach are now expected: additional requirements to define line of defense against adverse consequences of beyond design situations. The need for specific additional research activities after the Fukushima accident seems to be limited to some specific issues (for example spent fuel pool behaviour in case of long term loss of cooling). This paper is followed by the slides of the presentation

  3. [Great discoveries: from the painstaking efforts of researchers to the contribution of accidental findings and the dissemination of study results].

    Science.gov (United States)

    Garattini, Silvio

    2015-06-01

    This article takes its cue from the original work of sir Alexander Fleming on penicillin, published in the first issue of Recenti Progressi in Medicina in 1946 and reproduced here on the occasion of the approaching 70-year anniversary of the journal. The path that brought Fleming to the discovery of penicillin, one of the major milestones in the history of clinical pharmacology, provides insight for a range of considerations: the painstaking efforts of researchers, the contribution from accidental findings, and the dissemination of study results. Although the discovery of penicillin has changed the course of medicine, the benefits deriving from such an important advance are most likely to be offset by the overprescription of antibiotics, which is the leading cause of antimicrobial resistance and one of the most serious public health problems of our time.

  4. Coordinated research efforts for establishing an international radiotherapy dose intercomparison service based on the alanine/ESR system

    International Nuclear Information System (INIS)

    Nette, H.P.; Onori, S.; Fattibene, P.; Regulla, D.; Wieser, A.

    1993-01-01

    The IAEA has long been active in the field of high-dose standardization. An International Dose Assurance Service (IDAS) was established based on alanine/ESR dosimetry. This service operates over the range of 100 Gy to 100 kGy and is directed towards industrial radiation processing in IAEA member states. It complements the IAEA/WHO TLD postal dose intercomparison service for dose assurance in hospital radiotherapy departments. Experience with the alanine high dose service suggests that the alanine dosimeter might provide superior performance to TLD in the therapy dose range. Preliminary test measurements with the participation of GSF/Germany, Istituto Superiore di Sanita/Italy (both providing alanine dosimeters and their evaluation) and IAEA (providing reference irradiations) seems to justify research efforts through an IAEA Coordinated Research Programme (CRP). This CRP, entitled ''Therapy Level Dosimetry with the Alanine/ESR System'' is presently under set-up. It will include general work common to all assigned/potential contract holders as well as some specific research topics in accordance to individual proposals of each participant. (author)

  5. Engaging partners to initiate evaluation efforts: tactics used and lessons learned from the prevention research centers program.

    Science.gov (United States)

    Wright, Demia Sundra; Anderson, Lynda A; Brownson, Ross C; Gwaltney, Margaret K; Scherer, Jennifer; Cross, Alan W; Goodman, Robert M; Schwartz, Randy; Sims, Tom; White, Carol R

    2008-01-01

    The Centers for Disease Control and Prevention's (CDC's) Prevention Research Centers (PRC) Program underwent a 2-year evaluation planning project using a participatory process that allowed perspectives from the national community of PRC partners to be expressed and reflected in a national logic model. The PRC Program recognized the challenge in developing a feasible, useable, and relevant evaluation process for a large, diverse program. To address the challenge, participatory and utilization-focused evaluation models were used. Four tactics guided the evaluation planning process: 1) assessing stakeholders' communication needs and existing communication mechanisms and infrastructure; 2) using existing mechanisms and establishing others as needed to inform, educate, and request feedback; 3) listening to and using feedback received; and 4) obtaining adequate resources and building flexibility into the project plan to support multifaceted mechanisms for data collection. Participatory methods resulted in buy-in from stakeholders and the development of a national logic model. Benefits included CDC's use of the logic model for program planning and development of a national evaluation protocol and increased expectations among PRC partners for involvement. Challenges included the time, effort, and investment of program resources required for the participatory approach and the identification of whom to engage and when to engage them for feedback on project decisions. By using a participatory and utilization-focused model, program partners positively influenced how CDC developed an evaluation plan. The tactics we used can guide the involvement of program stakeholders and help with decisions on appropriate methods and approaches for engaging partners.

  6. Effortful echolalia.

    Science.gov (United States)

    Hadano, K; Nakamura, H; Hamanaka, T

    1998-02-01

    We report three cases of effortful echolalia in patients with cerebral infarction. The clinical picture of speech disturbance is associated with Type 1 Transcortical Motor Aphasia (TCMA, Goldstein, 1915). The patients always spoke nonfluently with loss of speech initiative, dysarthria, dysprosody, agrammatism, and increased effort and were unable to repeat sentences longer than those containing four or six words. In conversation, they first repeated a few words spoken to them, and then produced self initiated speech. The initial repetition as well as the subsequent self initiated speech, which were realized equally laboriously, can be regarded as mitigated echolalia (Pick, 1924). They were always aware of their own echolalia and tried to control it without effect. These cases demonstrate that neither the ability to repeat nor fluent speech are always necessary for echolalia. The possibility that a lesion in the left medial frontal lobe, including the supplementary motor area, plays an important role in effortful echolalia is discussed.

  7. Northeast Cooperative Research Study Fleet (SF) Program Combined GPS, Temperature/Depth, and Effort Fishery Dependent Data

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Temperature, depth(TD), GPS and haul by haul effort and catch data are collected during normal fishing activity of commercial fishing vessels participating in the...

  8. Development of an Internet-Administered Cognitive Behavior Therapy Program (ENGAGE) for Parents of Children Previously Treated for Cancer: Participatory Action Research Approach.

    Science.gov (United States)

    Wikman, Anna; Kukkola, Laura; Börjesson, Helene; Cernvall, Martin; Woodford, Joanne; Grönqvist, Helena; von Essen, Louise

    2018-04-18

    Parenting a child through cancer is a distressing experience, and a subgroup of parents report negative long-term psychological consequences years after treatment completion. However, there is a lack of evidence-based psychological interventions for parents who experience distress in relation to a child's cancer disease after end of treatment. One aim of this study was to develop an internet-administered, cognitive behavior therapy-based, psychological, guided, self-help intervention (ENGAGE) for parents of children previously treated for cancer. Another aim was to identify acceptable procedures for future feasibility and efficacy studies testing and evaluating the intervention. Participatory action research methodology was used. The study included face-to-face workshops and related Web-based exercises. A total of 6 parents (4 mothers, 2 fathers) of children previously treated for cancer were involved as parent research partners. Moreover, 2 clinical psychologists were involved as expert research partners. Research partners and research group members worked collaboratively throughout the study. Data were analyzed iteratively using written summaries of the workshops and Web-based exercises parallel to data collection. A 10-week, internet-administered, cognitive behavior therapy-based, psychological, guided, self-help intervention (ENGAGE) was developed in collaboration with parent research partners and expert research partners. The content of the intervention, mode and frequency of e-therapist support, and the individualized approach for feedback were modified based on the research partner input. Shared solutions were reached regarding the type and timing of support from an e-therapist (eg, initial video or telephone call, multiple methods of e-therapist contact), duration and timing of intervention (eg, 10 weeks, 30-min assessments), and the removal of unnecessary support functions (eg, removal of chat and forum functions). Preferences for study procedures in

  9. Crick's gossip test and Watson's boredom principle: A pseudo-mathematical analysis of effort in scientific research.

    Science.gov (United States)

    Charlton, Bruce G

    2008-01-01

    Crick and Watson gave complementary advice to the aspiring scientist based on the insight that to do your best work you need to make your greatest possible effort. Crick made the positive suggestion to work on the subject which most deeply interests you, the thing about which you spontaneously gossip - Crick termed this 'the gossip test'. Watson made the negative suggestion of avoiding topics and activities that bore you - which I have termed 'the boredom principle'. This is good advice because science is tough and the easy things have already been done. Solving the harder problems that remain requires a lot of effort. But in modern biomedical science individual effort does not necessarily correlate with career success as measured by salary, status, job security, etc. This is because Crick and Watson are talking about revolutionary science - using Thomas Kuhn's distinction between paradigm-shifting 'revolutionary' science and incremental 'normal' science. There are two main problems with pursuing a career in revolutionary science. The first is that revolutionary science is intrinsically riskier than normal science, the second that even revolutionary success in a scientific backwater may be less career-enhancing than mundane work in a trendy field. So, if you pick your scientific problem using the gossip test and the boredom principle, you might also be committing career suicide. This may explain why so few people follow Crick and Watson's advice. The best hope for future biomedical science is that it will evolve towards a greater convergence between individual effort and career success.

  10. Establishing an ethical climate in support of research integrity: efforts and activities of the American Sociological Association.

    Science.gov (United States)

    Iutcovich, Joyce M; Kennedy, John M; Levine, Felice J

    2003-04-01

    The article provides an overview of the recent efforts and activities of the American Sociological Association (ASA) to keep its Code of Ethics visible and relevant to its membership. The development process and challenges associated with the most recent revision of the ASA's code are reviewed, the current education and support activities are described, and other strategies for taking a proactive and leadership role in establishing an ethical climate are proposed. In conclusion, while the ASA has made significant progress in this area, it recognizes that a lot of work remains.

  11. Biomedical Big Data Training Collaborative (BBDTC): An effort to bridge the talent gap in biomedical science and research.

    Science.gov (United States)

    Purawat, Shweta; Cowart, Charles; Amaro, Rommie E; Altintas, Ilkay

    2017-05-01

    The BBDTC (https://biobigdata.ucsd.edu) is a community-oriented platform to encourage high-quality knowledge dissemination with the aim of growing a well-informed biomedical big data community through collaborative efforts on training and education. The BBDTC is an e-learning platform that empowers the biomedical community to develop, launch and share open training materials. It deploys hands-on software training toolboxes through virtualization technologies such as Amazon EC2 and Virtualbox. The BBDTC facilitates migration of courses across other course management platforms. The framework encourages knowledge sharing and content personalization through the playlist functionality that enables unique learning experiences and accelerates information dissemination to a wider community.

  12. Overcoming Limitations in Previous Research on Exercise as a Smoking Cessation Treatment: Rationale and Design of the “Quit for Health” Trial

    Science.gov (United States)

    Williams, David M.; Ussher, Michael; Dunsiger, Shira; Miranda, Robert; Gwaltney, Chad J.; Monti, Peter M.; Emerson, Jessica

    2013-01-01

    Aerobic exercise has been proposed as a stand-alone or adjunct smoking cessation treatment, but findings have been mixed. Laboratory studies have shown that individual exercise sessions lead to decreases in withdrawal symptoms and cigarette cravings, but findings are limited by lack of follow-up and artificial settings. On the other hand, smoking cessation treatment RCTs have generally failed to show positive effects of exercise on smoking cessation, but have been plagued by poor and/or unverified compliance with exercise programs. This paper describes the rationale and design for Quit for Health (QFH)—an RCT designed to determine the efficacy of aerobic exercise as an adjunct smoking cessation treatment among women. To overcome limitations of previous research, compliance with the exercise (and wellness contact control) program is incentivized and directly observed, and ecological momentary assessment is used to examine change over time in withdrawal symptoms and cigarette cravings in participants’ natural environments. PMID:24246818

  13. Community Advisory Boards Guiding Engaged Research Efforts within a Clinical Translational Sciences Award: Key Contextual Factors Explored.

    Science.gov (United States)

    Halladay, Jacqueline R; Donahue, Katrina E; Sleath, Betsy; Reuland, Dan; Black, Adina; Mitchell, C Madeline; Breland, Carol E; Coyne-Beasley, Tamera; Mottus, Kathleen; Watson, Sable Noelle; Lewis, Virginia; Wynn, Mysha; Corbie-Smith, Giselle

    2017-01-01

    Engaging stakeholders in research carries the promise of enhancing the research relevance, transparency, and speed of getting findings into practice. By describing the context and functional aspects of stakeholder groups, like those working as community advisory boards (CABs), others can learn from these experiences and operationalize their own CABs. Our objective is to describe our experiences with diverse CABs affiliated with our community engagement group within our institution's Clinical Translational Sciences Award (CTSA). We identify key contextual elements that are important to administering CABs. A group of investigators, staff, and community members engaged in a 6-month collaboration to describe their experiences of working with six research CABs. We identified the key contextual domains that illustrate how CABS are developed and sustained. Two lead authors, with experience with CABs and identifying contextual domains in other work, led a team of 13 through the process. Additionally, we devised a list of key tips to consider when devising CABs. The final domains include (1) aligned missions among stakeholders (2) resources/support, (3) defined operational processes/shared power, (4) well-described member roles, and (5) understanding and mitigating challenges. The tips are a set of actions that support the domains. Identifying key contextual domains was relatively easy, despite differences in the respective CAB's condition of focus, overall mission, or patient demographics represented. By contextualizing these five domains, other research and community partners can take an informed approach to move forward with CAB planning and engaged research.

  14. Recent Efforts in Advanced High Frequency Communications at the Glenn Research Center in Support of NASA Mission

    Science.gov (United States)

    Miranda, Felix A.

    2015-01-01

    This presentation will discuss research and technology development work at the NASA Glenn Research Center in advanced frequency communications in support of NASAs mission. An overview of the work conducted in-house and also in collaboration with academia, industry, and other government agencies (OGA) in areas such as antenna technology, power amplifiers, radio frequency (RF) wave propagation through Earths atmosphere, ultra-sensitive receivers, among others, will be presented. In addition, the role of these and other related RF technologies in enabling the NASA next generation space communications architecture will be also discussed.

  15. Effort in Multitasking: Local and Global Assessment of Effort.

    Science.gov (United States)

    Kiesel, Andrea; Dignath, David

    2017-01-01

    When performing multiple tasks in succession, self-organization of task order might be superior compared to external-controlled task schedules, because self-organization allows optimizing processing modes and thus reduces switch costs, and it increases commitment to task goals. However, self-organization is an additional executive control process that is not required if task order is externally specified and as such it is considered as time-consuming and effortful. To compare self-organized and externally controlled task scheduling, we suggest assessing global subjective and objectives measures of effort in addition to local performance measures. In our new experimental approach, we combined characteristics of dual tasking settings and task switching settings and compared local and global measures of effort in a condition with free choice of task sequence and a condition with cued task sequence. In a multi-tasking environment, participants chose the task order while the task requirement of the not-yet-performed task remained the same. This task preview allowed participants to work on the previously non-chosen items in parallel and resulted in faster responses and fewer errors in task switch trials than in task repetition trials. The free-choice group profited more from this task preview than the cued group when considering local performance measures. Nevertheless, the free-choice group invested more effort than the cued group when considering global measures. Thus, self-organization in task scheduling seems to be effortful even in conditions in which it is beneficiary for task processing. In a second experiment, we reduced the possibility of task preview for the not-yet-performed tasks in order to hinder efficient self-organization. Here neither local nor global measures revealed substantial differences between the free-choice and a cued task sequence condition. Based on the results of both experiments, we suggest that global assessment of effort in addition to

  16. The complex nature of mixed farming systems requires multidimensional actions supported by integrative research and development efforts

    DEFF Research Database (Denmark)

    González-García, E; Gourdine, J L; Alexandre, G

    2012-01-01

    the requirement for a change in research strategies and initiatives through the development of a complex but necessary multi-/inter-/trans-disciplinary teamwork spirit. We stress as essential the collaboration and active participation of local and regional actors, stakeholders and end-users in the identification...

  17. The complex nature of mixed farming systems requires multidimensional actions supported by integrative research and development efforts.

    Science.gov (United States)

    González-García, E; Gourdine, J L; Alexandre, G; Archimède, H; Vaarst, M

    2012-05-01

    Mixed farming systems (MFS) have demonstrated some success by focusing on the use of integrative and holistic mechanisms, and rationally building on and using the natural and local resource base without exhausting it, while enhancing biodiversity, optimizing complementarities between crops and animal systems and finally increasing opportunities in rural livelihoods. Focusing our analysis and discussion on field experiences and empirical knowledge in the Caribbean islands, this paper discusses the opportunities for a change needed in current MFS research-development philosophy. The importance of shifting from fragile/specialized production systems to MFS under current global conditions is argued with an emphasis on the case of Small Islands Developing States (SIDS) and the Caribbean. Particular vulnerable characteristics as well as the potential and constraints of SIDS and their agricultural sectors are described, while revealing the opportunities for the 'richness' of the natural and local resources to support authentic and less dependent production system strategies. Examples are provided of the use of natural grasses, legumes, crop residues and agro-industrial by-products. We analyse the requirement for a change in research strategies and initiatives through the development of a complex but necessary multi-/inter-/trans-disciplinary teamwork spirit. We stress as essential the collaboration and active participation of local and regional actors, stakeholders and end-users in the identification of research priorities, as well as the generation, exchange and dissemination of knowledge and technology innovations, while strengthening the leadership roles in the conduct of integrative and participative research and development projects.

  18. Human-centered automation and AI - Ideas, insights, and issues from the Intelligent Cockpit Aids research effort

    Science.gov (United States)

    Abbott, Kathy H.; Schutte, Paul C.

    1989-01-01

    A development status evaluation is presented for the NASA-Langley Intelligent Cockpit Aids research program, which encompasses AI, human/machine interfaces, and conventional automation. Attention is being given to decision-aiding concepts for human-centered automation, with emphasis on inflight subsystem fault management, inflight mission replanning, and communications management. The cockpit envisioned is for advanced commercial transport aircraft.

  19. The Process of Planning and Designing Research for an Educational Telecommunications Effort. Satellite Technology Demonstration, Technical Report No. 0209.

    Science.gov (United States)

    Connolly, A. J.; And Others

    The Satellite Technology Demonstration (STD) designed research for a satellite-based communication system that would transmit educational television programs. Their procedures were subject to a series of external and internal evaluations by the project sponsors, the National Institute of Education. In regard to external evaluation, STD recommended…

  20. Biomedical Big Data Training Collaborative (BBDTC): An effort to bridge the talent gap in biomedical science and research.

    Science.gov (United States)

    Purawat, Shweta; Cowart, Charles; Amaro, Rommie E; Altintas, Ilkay

    2016-06-01

    The BBDTC (https://biobigdata.ucsd.edu) is a community-oriented platform to encourage high-quality knowledge dissemination with the aim of growing a well-informed biomedical big data community through collaborative efforts on training and education. The BBDTC collaborative is an e-learning platform that supports the biomedical community to access, develop and deploy open training materials. The BBDTC supports Big Data skill training for biomedical scientists at all levels, and from varied backgrounds. The natural hierarchy of courses allows them to be broken into and handled as modules . Modules can be reused in the context of multiple courses and reshuffled, producing a new and different, dynamic course called a playlist . Users may create playlists to suit their learning requirements and share it with individual users or the wider public. BBDTC leverages the maturity and design of the HUBzero content-management platform for delivering educational content. To facilitate the migration of existing content, the BBDTC supports importing and exporting course material from the edX platform. Migration tools will be extended in the future to support other platforms. Hands-on training software packages, i.e., toolboxes , are supported through Amazon EC2 and Virtualbox virtualization technologies, and they are available as: ( i ) downloadable lightweight Virtualbox Images providing a standardized software tool environment with software packages and test data on their personal machines, and ( ii ) remotely accessible Amazon EC2 Virtual Machines for accessing biomedical big data tools and scalable big data experiments. At the moment, the BBDTC site contains three open Biomedical big data training courses with lecture contents, videos and hands-on training utilizing VM toolboxes, covering diverse topics. The courses have enhanced the hands-on learning environment by providing structured content that users can use at their own pace. A four course biomedical big data series is

  1. Using research to change public policy: reflections on 20 years of effort to eliminate corporal punishment in schools.

    Science.gov (United States)

    Hyman, I A

    1996-10-01

    In the past 20 years, over half of the states have abolished corporal punishment in schools. Without the use of ethically questionable, experimental studies in which students were randomly assigned to paddlings, advocacy researchers were able to integrate the literature and experimental research on reward, punishment, and motivation, and conduct enough studies to provide sufficient data for policy changes. Further, every popular school discipline training program promotes well-proven positive and preventive techniques and punishments that do not inflict physical pain. Research on alternatives, naturalistic evidence from schools that eliminated corporal punishment, and survey research prove that schools do not need to use corporal punishment. The movement to eliminate parental spanking is at a stage similar to the beginning of the school corporal punishment debate in 1976. Even though some studies may show that moderate parental spanking may do no short-term harm, there is little scientific evidence that it is necessary. There are no data to indicate that schools which eliminated corporal punishment became any worse. The same demographic factors and political polarizations that have kept about half of American school children from the protections against paddling afforded students in almost all other Western democracies also impede the movement to eliminate parental spanking. Since we know that corporal punishment too often leads to excesses, and since we have a multitude of effective positive approaches, what is the worst thing that would happen if all Americans stopped hitting children in any setting? The same children who are hit for misbehavior would continue that misbehavior and other ineffective punishments would be used. Most parents and teachers would discover what behavioral scientists already know. A combination of reward, positive motivational techniques and appropriate, nonphysical punishments would prevent most misbehavior. Other factors being equal, in

  2. The Use of Dual Task Paradigms in Memory Research: A Methodological Assessment and an Evaluation of Effort as a Measure of Levels of Processing.

    Science.gov (United States)

    1982-03-01

    sustained monitoring tasks. Human Factors, 1979, 21, 647-653. Craik , F. I. M., & Lockhart , R. Levels of processing : A framework for memory research...original levels approach to human memory ( Craik & Lockhart , 1972) contended that verbal stimuli could be classified along a continuum ranging from...AND AN EVALUATION OF EFFORT AS A MEASURr OF LEVELS OF PROCESSING Arthur D. Fisk, William L. Derrick, and Walter Schneider REPORT HARL-ONR-8105 E. C

  3. Start Up Research Effort in Fluid Mechanics. Advanced Methods for Acoustic and Thrust Benefits for Aircraft Engine Nozzle

    Science.gov (United States)

    White, Samuel G.; Gilinsky, Mikhail M.

    1997-01-01

    In accordance with the project plan for the report period in the proposal titled above, HU and FML teams investigated two sets of concepts for reduction of noise and improvement in efficiency for jet exhaust nozzles of aircraft engines and screws for mixers, fans, propellers and boats. The main achievements in the report period are: (a) Publication of the paper in the AIAA Journal, which described our concepts and some results. (b) The Award in the Civil Research and Development Foundation (CRDF) competition. This 2 year grant for Hampton University (HU) and Central AeroHydrodynamic Institute (TSAGI, Moscow, Russia) supports the research implementation under the current NASA FAR grant. (c) Selection for funding by NASA HQ review panel of the Partnership Awards Concept Paper. This two year grant also will support our current FAR grant. (d) Publication of a Mobius Strip concept in NASA Technical Briefs, June, 1996, and a great interest of many industrial companies in this invention. Successful experimental results with the Mobius shaped screw for mixers, which save more than 30% of the electric power by comparison with the standard screws. Creation of the scientific-popular video-film which can be used for commercial and educational purposes. (e) Organization work, joint meetings and discussions of the NASA LARC JNL Team and HU professors and administration for the solution of actual problems and effective work of the Fluid Mechanics Laboratory at Hampton University. In this report the main designs are enumerated. It also contains for both concept sets: (1) the statement of the problem for each design, some results, publications, inventions, patents, our vision for continuation of this research, and (2) present and expected problems in the future.

  4. Discrimination of Closely-Spaced Geosynchronous Satellites - Phase Curve Analysis & New Small Business Innovative Research (SBIR) Efforts

    Science.gov (United States)

    Levan, P.

    2010-09-01

    Geosynchronous objects appear as unresolved blurs even when observed with the largest ground-based telescopes. Due to the lack of any spatial detail, two or more objects appearing at similar brightness levels within the spectral bandpass they are observed are difficult to distinguish. Observing a changing pattern of such objects from one time epoch to another showcases the deficiencies in associating individual objects before and after the configuration change. This paper explores solutions to this deficiency in the form of spectral (under small business innovative research) and phase curve analyses. The extension of the technique to phase curves proves to be a powerful new capability.

  5. Overcoming limitations in previous research on exercise as a smoking cessation treatment: rationale and design of the "Quit for Health" trial.

    Science.gov (United States)

    Williams, David M; Ussher, Michael; Dunsiger, Shira; Miranda, Robert; Gwaltney, Chad J; Monti, Peter M; Emerson, Jessica

    2014-01-01

    Aerobic exercise has been proposed as a stand-alone or adjunct smoking cessation treatment, but findings have been mixed. Laboratory studies have shown that individual exercise sessions lead to decreases in withdrawal symptoms and cigarette cravings, but findings are limited by lack of follow-up and artificial settings. On the other hand, smoking cessation treatment RCTs have generally failed to show positive effects of exercise on smoking cessation, but have been plagued by poor and/or unverified compliance with exercise programs. This paper describes the rationale and design for Quit for Health (QFH)--an RCT designed to determine the efficacy of aerobic exercise as an adjunct smoking cessation treatment among women. To overcome limitations of previous research, compliance with the exercise (and wellness contact control) program is incentivized and directly observed, and ecological momentary assessment is used to examine change over time in withdrawal symptoms and cigarette cravings in participants' natural environments. Copyright © 2013 Elsevier Inc. All rights reserved.

  6. Review of the nutritional implications of farmers' markets and community gardens: a call for evaluation and research efforts.

    Science.gov (United States)

    McCormack, Lacey Arneson; Laska, Melissa Nelson; Larson, Nicole I; Story, Mary

    2010-03-01

    The development and promotion of farmers' markets and community gardens is growing in popularity as a strategy to increase community-wide fruit and vegetable consumption. Despite large numbers of farmers' markets and community gardens in the United States, as well as widespread enthusiasm for their use as a health promotion tool, little is known about their influence on dietary intake. This review examines the current scientific literature on the implications of farmers' market programs and community gardens on nutrition-related outcomes in adults. Studies published between January 1980 and January 2009 were identified via PubMed and Agricola database searches and by examining reference lists from relevant studies. Studies were included in this review if they took place in the United States and qualitatively or quantitatively examined nutrition-related outcomes, including dietary intake; attitudes and beliefs regarding buying, preparing, or eating fruits and vegetables; and behaviors and perceptions related to obtaining produce from a farmers' market or community garden. Studies focusing on garden-based youth programs were excluded. In total, 16 studies were identified for inclusion in this review. Seven studies focused on the impact of farmers' market nutrition programs for Special Supplemental Nutrition Program for Women, Infants, and Children participants, five focused on the influence of farmers' market programs for seniors, and four focused on community gardens. Findings from this review reveal that few well-designed research studies (eg, those incorporating control groups) utilizing valid and reliable dietary assessment methods to evaluate the influence of farmers' markets and community gardens on nutrition-related outcomes have been completed. Recommendations for future research on the dietary influences of farmers' markets and community gardens are provided. Copyright 2010 American Dietetic Association. Published by Elsevier Inc. All rights reserved.

  7. Continued internal and external research efforts of RAG. New insights for the geological evolution of the Molasse Basin of Austria

    Energy Technology Data Exchange (ETDEWEB)

    Hinsch, R. [Rohoel-Aufsuchungs AG, Vienna (Austria)

    2008-10-23

    The understanding of the detailed geological evolution of the Molasse Basin is crucial for the continued success of exploration in this mature basin. Results from several research projects help to find new play types and increase the understanding of stratigraphic traps by characterising the sedimentological processes that control them. Risks associated with play types can be better assessed considering their evolutionary framework. Several studies focussed on that subject have been concluded in recent years or are still ongoing. This presentation will give an overview of the objectives, results and implications of these initiatives for evaluation and analysis of the geological evolution and for exploration of the Molasse Basin. An initial collaboration with Stanford University integrated sedimentological core analyses with 3D seismic, wireline log data interpretation and outcrop studies in analogue settings. The study yielded a modern sedimentological model for the Upper Puchkirchen Formation which was subsequently applied to exploration. A sequence stratigraphic study examined the sequence framework of the Molasse Basin fill and was able to correlate 5 sequences from the shelf into the deep basin. Studies on seismic and core analyses from the south slope of the Puchkirchen trough show how slope morphology and confinement control sediment distribution in the southern slope deposits. The transition from deep to more shallow marine conditions and the progradation of deltaic sequences into the basin in Eggenburgian/Burdigalian times is described by an intense 3-D seismic interpretation in combination with sedimentological core work. Working on a more local scale, other projects are improving the understanding of the detailed architecture of distinct play elements such as the Upper Puchkirchen Channel or the Basal Hall Formation Channel. In general, these studies highlight the complex interaction of processes that control sediment distribution in the basin. Morphology

  8. Contaminated Sediment Management in Dam Removals and River Restoration Efforts: Critical Need for Research and Policy Development

    Science.gov (United States)

    Evans, J. E.

    2015-12-01

    Over 1,000 U.S. dams have been removed (1975-2015) for reasons including obsolescence, liability concerns, water quality upgrades, fisheries, or ecosystem enhancements. Contaminated sediment can significantly complicate the approval process, cost, and timeline of a dam removal, or stop it entirely. In a dam removal, reservoir sediment changes from a sink to a source of contaminants. Recently, the Sierra Club sued to stop the removal of a large dam in Ohio because of the potential impact of phosphate releases on toxic algal blooms in Lake Erie. Heavy metals, PCBs, PAHs, pesticides, and petroleum hydrocarbons can be present in reservoir sediments. In a non-dam removal scenario, reservoir management tools range from "no action" to dredging, dewatering and removal, or sediment capping. But it is not clear how these reservoir management techniques apply to dam removals. Case studies show typically >80% of the reservoir sediment is eventually eroded, precluding sediment capping as a containment option. However, the released contaminants are diluted by mixing with "clean" sediment and are transported to different physio-chemical environments which may immobilize or biodegrade the contaminants. Poorly understood options include phased drawdown/reseeding the former reservoir to contain sediments, diking contaminant "hot spots," and addressing contaminant stratigraphy (where historical use created "hot layers" in the reservoir sediment). Research and policy development needs include: (1) assessment methods based on synergistic effects of multiple contaminants being present; (2) ways to translate the pre-removal contaminant concentrations to post-removal health risks downstream; (3) evaluation of management practices for contaminant "hot spots" and "hot layers;" (4) tools to forecast the presence of contaminated sediment using easily accessible information; and (5) ways to limit liability risk for organizations participating in dam removals involving contaminated sediment.

  9. Metal loading in Soda Butte Creek upstream of Yellowstone National Park, Montana and Wyoming; a retrospective analysis of previous research; and quantification of metal loading, August 1999

    Science.gov (United States)

    Boughton, G.K.

    2001-01-01

    Acid drainage from historic mining activities has affected the water quality and aquatic biota of Soda Butte Creek upstream of Yellowstone National Park. Numerous investigations focusing on metals contamination have been conducted in the Soda Butte Creek basin, but interpretations of how metals contamination is currently impacting Soda Butte Creek differ greatly. A retrospective analysis of previous research on metal loading in Soda Butte Creek was completed to provide summaries of studies pertinent to metal loading in Soda Butte Creek and to identify data gaps warranting further investigation. Identification and quantification of the sources of metal loading to Soda Butte Creek was recognized as a significant data gap. The McLaren Mine tailings impoundment and mill site has long been identified as a source of metals but its contribution relative to the total metal load entering Yellowstone National Park was unknown. A tracer-injection and synoptic-sampling study was designed to determine metal loads upstream of Yellowstone National Park.A tracer-injection and synoptic-sampling study was conducted on an 8,511-meter reach of Soda Butte Creek from upstream of the McLaren Mine tailings impoundment and mill site downstream to the Yellowstone National Park boundary in August 1999. Synoptic-sampling sites were selected to divide the creek into discrete segments. A lithium bromide tracer was injected continuously into Soda Butte Creek for 24.5 hours. Downstream dilution of the tracer and current-meter measurements were used to calculate the stream discharge. Stream discharge values, combined with constituent concentrations obtained by synoptic sampling, were used to quantify constituent loading in each segment of Soda Butte Creek.Loads were calculated for dissolved calcium, silica, and sulfate, as well as for dissolved and total-recoverable iron, aluminum, and manganese. Loads were not calculated for cadmium, copper, lead, and zinc because these elements were infrequently

  10. Taxonomies in L1 and L2 Reading Strategies: A Critical Review of Issues Surrounding Strategy-Use Definitions and Classifications in Previous Think-Aloud Research

    Science.gov (United States)

    Alkhaleefah, Tarek A.

    2016-01-01

    Considering the various classifications of L1 and L2 reading strategies in previous think-aloud studies, the present review aims to provide a comprehensive look into those various taxonomies reported in major L1 and L2 reading studies. The rationale for this review is not only to offer a comprehensive overview of the different classifications in…

  11. The Efforts of the American Geophysical Union Space Physics and Aeronomy Section Education and Public Outreach Committee to Use NASA Research in Education and Outreach

    Science.gov (United States)

    Bering, E. A., III; Dusenbery, P.; Gross, N. A.; Johnson, R.; Lopez, R. E.; Lysak, R. L.; Moldwin, M.; Morrow, C. A.; Nichols-Yehling, M.; Peticolas, L. M.; Reiff, P. H.; Scherrer, D. K.; Thieman, J.; Wawro, M.; Wood, E. L.

    2017-12-01

    The American Geophysical Union Space Physics and Aeronomy Section Education and Public Outreach Committee (AGU SPA-EPO Committee) was established in 1990 to foster the growth of a culture of outreach and community engagement within the SPA Section of the AGU. The SPA was the first AGU Section to establish an EPO Committee. The Committee has initiated several key Section EPO programs that have grown to become Union programs. NASA sponsored research is central to the mission of the SPE-EPO. Programs highlighting NASA research include the Student Paper Competition, Exploration Station, a precursor to the GIFT workshops, the Student mixer, and more. The Committee played a key role in coordinating the AGU's outreach activities relating to the International Heliophysical Year in 2007-2008. This paper will review the triumphs, the failures, and the lessons learned about recruiting colleagues to join with us from the last quarter century of effort.

  12. Explaining Research Utilization Among 4-H Faculty, Staff, and Volunteers: The Role of Self-Efficacy, Learning Goal Orientation, Training, and Previous Experience

    Directory of Open Access Journals (Sweden)

    Julianne Tillman

    2014-06-01

    Full Text Available An investigation of factors that facilitate the utilization of research evidence among faculty, staff, and volunteers in the 4-H Youth Development Program is presented in this paper. Participants (N= 368; 86 4-H faculty, 153 staff, and 129 volunteers represented 35 states; structural equation modeling was utilized in the analyses. Results of the path analysis explained 56% of variance in research utilization and 28% in research utilization self-efficacy. Among the factors impacting research utilization, self-efficacy played the most important role. In turn, self-efficacy for research utilization was positively influenced by participants’ learning goal orientation, frequency of 4-H training during the last 12 months, education in research-related areas, and investigative career interests. In addition, 4-H staff who were exposed to research at higher levels reported higher research utilization self-efficacy. The findings reinforce the importance of fostering research utilization self-efficacy among 4-H faculty, staff, and volunteers. Among the suggestions presented are regular 4-H training opportunities and on-going exposure to program evaluation and program improvement experiences.

  13. The difference biocultural "place" makes to community efforts towards sustainable development: Youth participatory action research in a marine protected area of Colombia

    Science.gov (United States)

    McRuer, Jennifer; Zethelius, Margarita

    2017-12-01

    The Latin American concept of "(collective) biocultural heritage" arose from Indigenous knowledge and practices with respect to local natural resources and environment, including the food being hunted, the crops being grown, and the landscapes being created. The term is now used more widely to describe community practices, goals and priorities that are determined, maintained and managed by diverse cultural relationships with "place". The study presented in this article investigated biocultural place relationships in connection with well-being and sustainability. In the context of learning and action for sustainability in Isla Grande, an island in a marine protected area of Colombia, this study targeted the significance of place to the everyday lives of Afro-Colombian youth - from their perspective. Beyond aiming to merely observe and collect data, the methodology included a research design which actively involved local youth and incorporated the aspect of place. The authors describe and reflect on the processes, learning and action that emerged throughout the research, as well as the study's limitations. They discuss broad implications in terms of how place relationships influence research, and how research influences place relationships. Local implications include supporting the voice of youth in community efforts to re-imagine and transform place relationships in response to critical place issues such as climate change, top-down resource management, privatisation, commodification and growing environmental injustice.

  14. Submerged Medium Voltage Cable Systems at Nuclear Power Plants. A Review of Research Efforts Relevant to Aging Mechanisms and Condition Monitoring

    Energy Technology Data Exchange (ETDEWEB)

    Brown, Jason [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Bernstein, Robert [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); White, II, Gregory Von [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Glover, Steven F. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Neely, Jason C. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Pena, Gary [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Williamson, Kenneth Martin [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Zutavern, Fred J. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Gelbard, Fred [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2015-03-01

    In a submerged environment, power cables may experience accelerated insulation degradation due to water - related aging mechanisms . Direct contact with water or moisture intrusion in the cable insulation s ystem has been identified in the literature as a significant aging stressor that can affect performance and lifetime of electric cables . Progressive reduction of the dielectric strength is commonly a result of water treeing which involves the development of permanent hydrophilic structures in the insulation coinciding with the absorption of water into the cable . Water treeing is a phenomenon in which dendritic microvoids are formed in electric cable insulation due to electrochemic al reactions , electromechanical forces , and diffusion of contaminants over time . These reactions are caused by the combined effect s of water presence and high electrical stress es in the material . Water tree growth follow s a tree - like branching pattern , i ncreasing in volume and length over time . Although these cables can be "dried out," water tree degradation , specifically the growth of hydrophilic regions, is believed to be permanent and typically worsens over time. Based on established research , water treeing or water induced damage can occur in a variety of electric cables including XLPE, TR - XLPE and other insulating materials, such as EPR and butyl rubber . Once water trees or water induced damage form, the dielectric strength of an insulation materia l will decrease gradually with time as the water trees grow in length, which could eventually result in failure of the insulating material . Under wet conditions or i n submerged environments , several environmental and operational parameters can influence w ater tree initiation and affect water tree growth . These parameters include voltage cycling, field frequency, temperature, ion concentration and chemistry, type of insula tion material , and the characteristics of its defects. In this effort, a review of academic

  15. Laparoscopy After Previous Laparotomy

    Directory of Open Access Journals (Sweden)

    Zulfo Godinjak

    2006-11-01

    Full Text Available Following the abdominal surgery, extensive adhesions often occur and they can cause difficulties during laparoscopic operations. However, previous laparotomy is not considered to be a contraindication for laparoscopy. The aim of this study is to present that an insertion of Veres needle in the region of umbilicus is a safe method for creating a pneumoperitoneum for laparoscopic operations after previous laparotomy. In the last three years, we have performed 144 laparoscopic operations in patients that previously underwent one or two laparotomies. Pathology of digestive system, genital organs, Cesarean Section or abdominal war injuries were the most common causes of previouslaparotomy. During those operations or during entering into abdominal cavity we have not experienced any complications, while in 7 patients we performed conversion to laparotomy following the diagnostic laparoscopy. In all patients an insertion of Veres needle and trocar insertion in the umbilical region was performed, namely a technique of closed laparoscopy. Not even in one patient adhesions in the region of umbilicus were found, and no abdominal organs were injured.

  16. Populating a Control Point Database: A cooperative effort between the USGS, Grand Canyon Monitoring and Research Center and the Grand Canyon Youth Organization

    Science.gov (United States)

    Brown, K. M.; Fritzinger, C.; Wharton, E.

    2004-12-01

    The Grand Canyon Monitoring and Research Center measures the effects of Glen Canyon Dam operations on the resources along the Colorado River from Glen Canyon Dam to Lake Mead in support of the Grand Canyon Adaptive Management Program. Control points are integral for geo-referencing the myriad of data collected in the Grand Canyon including aerial photography, topographic and bathymetric data used for classification and change-detection analysis of physical, biologic and cultural resources. The survey department has compiled a list of 870 control points installed by various organizations needing to establish a consistent reference for data collected at field sites along the 240 mile stretch of Colorado River in the Grand Canyon. This list is the foundation for the Control Point Database established primarily for researchers, to locate control points and independently geo-reference collected field data. The database has the potential to be a valuable mapping tool for assisting researchers to easily locate a control point and reduce the occurrance of unknowingly installing new control points within close proximity of an existing control point. The database is missing photographs and accurate site description information. Current site descriptions do not accurately define the location of the point but refer to the project that used the point, or some other interesting fact associated with the point. The Grand Canyon Monitoring and Research Center (GCMRC) resolved this problem by turning the data collection effort into an educational exercise for the participants of the Grand Canyon Youth organization. Grand Canyon Youth is a non-profit organization providing experiential education for middle and high school aged youth. GCMRC and the Grand Canyon Youth formed a partnership where GCMRC provided the logistical support, equipment, and training to conduct the field work, and the Grand Canyon Youth provided the time and personnel to complete the field work. Two data

  17. Cognitive effort: A neuroeconomic approach

    Science.gov (United States)

    Braver, Todd S.

    2015-01-01

    Cognitive effort has been implicated in numerous theories regarding normal and aberrant behavior and the physiological response to engagement with demanding tasks. Yet, despite broad interest, no unifying, operational definition of cognitive effort itself has been proposed. Here, we argue that the most intuitive and epistemologically valuable treatment is in terms of effort-based decision-making, and advocate a neuroeconomics-focused research strategy. We first outline psychological and neuroscientific theories of cognitive effort. Then we describe the benefits of a neuroeconomic research strategy, highlighting how it affords greater inferential traction than do traditional markers of cognitive effort, including self-reports and physiologic markers of autonomic arousal. Finally, we sketch a future series of studies that can leverage the full potential of the neuroeconomic approach toward understanding the cognitive and neural mechanisms that give rise to phenomenal, subjective cognitive effort. PMID:25673005

  18. Social participation: redesign of education, research, and practice in occupational therapy. Previously published in Scandinavian Journal of Occupational Therapy 2013; 20: 2-8.

    Science.gov (United States)

    Piškur, Barbara

    2014-01-01

    There is growing attention to participation and social participation in literature and policy reports. Occupational therapists strongly believe that creating coherence between the person's occupations and environment will facilitate participation of each individual. Nowadays, societal developments such as "health literacy and self-management", "Web 2.0 social media", "empowering communities", and "Nothing About Us Without Us" increase opportunities for people to interact on different levels of social participation. Social participation can be used as an outcome, though it can also be seen as a means to change society and to develop solutions for barriers experienced by people with chronic diseases or disabilities. Societal developments will have an impact on social participation in terms of supporting each other and contributing to society. Additionally, these changes will have a major influence on the way we educate, conduct research, and deliver occupational therapy practice.

  19. Lessons from previous 'coal Transitions'. High-level summary for decision-makers, Part of 'Coal Transitions: Research and Dialogue on the Future of Coal' Project

    International Nuclear Information System (INIS)

    Caldecott, Ben; Sartor, Oliver; Spencer, Thomas

    2017-01-01

    The need for a so-called 'just transition' is acknowledged, away from carbon intensive activities, such as coal production and use. But what might a just transition look like in practice? What specific risks need to be managed and what are the best approaches to managing them? There is an urgent need to develop a deeper understanding of these issues. It is to this need that this report tries to respond. It provides a summary of lessons from six historical case studies of regional coal mining transitions that have occurred or are ongoing in Europe and the United States in recent decades. These case studies and this report were developed as part of a broader project led by IDDRI and Climate Strategies, entitled 'Coal Transitions: Research and Dialogue on the Future of Coal'. This project seeks to utilise these historical lessons to facilitate the development of feasible coal transition scenarios in large coal producing countries today'

  20. Research and implementation of novel approaches for the control of nematode parasites in Latin America and the Caribbean: is there sufficient incentive for a greater extension effort?

    Science.gov (United States)

    Torres-Acosta, J F J; Molento, M; Mendoza de Gives, P

    2012-05-04

    The widespread presence of anthelmintic resistant gastrointestinal parasitic nematodes in outdoor ruminant production systems has driven the need to identify and develop novel approaches for the control of helminths with the intention to reduce the dependence on commercial anthelmintic drugs. This paper identifies what has been done in Latin America (LA) in terms of estimating the prevalence of anthelmintic resistance (AR) in ruminant production systems and the application of different novel approaches for the control of helminths in those systems, including research and extension activities. Firstly, the paucity of knowledge of AR is discussed in the context of different countries, as well as, the available economic resources for research, the technical infrastructure available and the practical difficulties of the production systems. It is then proposed that the search for novel approaches is not only driven by AR but also by the need for techniques that are feasible for application by resource-poor farmers in non-commercial subsistence farming systems. However, the commercial benefits of these approaches are often limited and so are funding inputs in most countries. The workers participating in the research into different novel approaches are identified as well as the different methods being studied in the different areas of LA according to their published results. In addition, the difficulties experienced during extension efforts to reach farmers and help them to adopt novel approaches for the control of parasitic nematodes in LA are discussed. The role of regulatory authorities in these countries is discussed as some methods of control might need an official confirmation of their efficacy as well as authorization prior to application as they may affect animal products (i.e. residues) and/or impose a hazard for animal welfare. The role of the pharmaceutical companies is also discussed. Copyright © 2011. Published by Elsevier B.V.

  1. Exploring Challenges and Opportunities of Coproduction: USDA Climate Hub Efforts to Integrate Coproduction with Applied Research and Decision Support Tool Development in the Northwest

    Science.gov (United States)

    Roesch-McNally, G.; Prendeville, H. R.

    2017-12-01

    A lack of coproduction, the joint production of new technologies or knowledge among technical experts and other groups, is arguably one of the reasons why much scientific information and resulting decision support systems are not very usable. Increasingly, public agencies and academic institutions are emphasizing the importance of coproduction of scientific knowledge and decision support systems in order to facilitate greater engagement between the scientific community and key stakeholder groups. Coproduction has been embraced as a way for the scientific community to develop actionable scientific information that will assist end users in solving real-world problems. Increasing the level of engagement and stakeholder buy-in to the scientific process is increasingly necessary, particularly in the context of growing politicization of science and the scientific process. Coproduction can be an effective way to build trust and can build-on and integrate local and traditional knowledge. Employing coproduction strategies may enable the development of more relevant and useful information and decision support tools that address stakeholder challenges at relevant scales. The USDA Northwest Climate Hub has increasingly sought ways to integrate coproduction in the development of both applied research projects and the development of decision support systems. Integrating coproduction, however, within existing institutions is not always simple, given that coproduction is often more focused on process than products and products are, for better or worse, often the primary focus of applied research and tool development projects. The USDA Northwest Climate Hub sought to integrate coproduction into our FY2017 call for proposal process. As a result we have a set of proposals and fledgling projects that fall along the engagement continuum (see Figure 1- attached). We will share the challenges and opportunities that emerged from this purposeful integration of coproduction into the work

  2. DOE Research and Development Accomplishments Previous Highlights

    Science.gov (United States)

    through his Nobel Lecture in 1961, about unraveling the secrets of photosynthesis -- the process by which . March 10, 2015 Twenty years ago, the top quark was first observed in experiments at the Tevatron proton sophisticated detectors, the top was hard to find. After a top is made from a proton-antiproton collision, a

  3. Effort rights-based management

    DEFF Research Database (Denmark)

    Squires, Dale; Maunder, Mark; Allen, Robin

    2017-01-01

    Effort rights-based fisheries management (RBM) is less widely used than catch rights, whether for groups or individuals. Because RBM on catch or effort necessarily requires a total allowable catch (TAC) or total allowable effort (TAE), RBM is discussed in conjunction with issues in assessing fish...... populations and providing TACs or TAEs. Both approaches have advantages and disadvantages, and there are trade-offs between the two approaches. In a narrow economic sense, catch rights are superior because of the type of incentives created, but once the costs of research to improve stock assessments...

  4. Maximum effort in the minimum-effort game

    Czech Academy of Sciences Publication Activity Database

    Engelmann, Dirk; Normann, H.-T.

    2010-01-01

    Roč. 13, č. 3 (2010), s. 249-259 ISSN 1386-4157 Institutional research plan: CEZ:AV0Z70850503 Keywords : minimum-effort game * coordination game * experiments * social capital Subject RIV: AH - Economics Impact factor: 1.868, year: 2010

  5. Estimation of inspection effort

    International Nuclear Information System (INIS)

    Mullen, M.F.; Wincek, M.A.

    1979-06-01

    An overview of IAEA inspection activities is presented, and the problem of evaluating the effectiveness of an inspection is discussed. Two models are described - an effort model and an effectiveness model. The effort model breaks the IAEA's inspection effort into components; the amount of effort required for each component is estimated; and the total effort is determined by summing the effort for each component. The effectiveness model quantifies the effectiveness of inspections in terms of probabilities of detection and quantities of material to be detected, if diverted over a specific period. The method is applied to a 200 metric ton per year low-enriched uranium fuel fabrication facility. A description of the model plant is presented, a safeguards approach is outlined, and sampling plans are calculated. The required inspection effort is estimated and the results are compared to IAEA estimates. Some other applications of the method are discussed briefly. Examples are presented which demonstrate how the method might be useful in formulating guidelines for inspection planning and in establishing technical criteria for safeguards implementation

  6. How much longer will Africa have to depend on western nations for support of its capacity-building efforts for biomedical research?

    Science.gov (United States)

    Laabes, Emmanuel Philip; Desai, Rizwana; Zawedde, Stella Muyanja; Glew, Robert Hayes

    2011-03-01

    Advances in biomedical research techniques have resulted in the conquest of many diseases and the improvement in the health and well-being of populations, yet sub-Saharan Africa continues to lag behind western nations in terms of research infrastructure and capacity. The increasing numbers of links and collaborations between western institutions of higher learning and teaching hospitals and universities in sub-Saharan Africa have undoubtedly promoted scholarly research activity on the continent. However, most of the research agenda is, understandably, dominated by western collaborators who provide the much needed funding. Given the recent exposure by events on Wall Street of the frailties of western economies, Africa urgently needs to look inwards in its quest to train biomedical researchers of repute and to secure funding for its capacity-building needs. © 2011 Blackwell Publishing Ltd.

  7. Swedish nuclear waste efforts

    International Nuclear Information System (INIS)

    Rydberg, J.

    1981-09-01

    After the introduction of a law prohibiting the start-up of any new nuclear power plant until the utility had shown that the waste produced by the plant could be taken care of in an absolutely safe way, the Swedish nuclear utilities in December 1976 embarked on the Nuclear Fuel Safety Project, which in November 1977 presented a first report, Handling of Spent Nuclear Fuel and Final Storage of Vitrified Waste (KBS-I), and in November 1978 a second report, Handling and Final Storage of Unreprocessed Spent Nuclear Fuel (KBS II). These summary reports were supported by 120 technical reports prepared by 450 experts. The project engaged 70 private and governmental institutions at a total cost of US $15 million. The KBS-I and KBS-II reports are summarized in this document, as are also continued waste research efforts carried out by KBS, SKBF, PRAV, ASEA and other Swedish organizations. The KBS reports describe all steps (except reprocessing) in handling chain from removal from a reactor of spent fuel elements until their radioactive waste products are finally disposed of, in canisters, in an underground granite depository. The KBS concept relies on engineered multibarrier systems in combination with final storage in thoroughly investigated stable geologic formations. This report also briefly describes other activities carried out by the nuclear industry, namely, the construction of a central storage facility for spent fuel elements (to be in operation by 1985), a repository for reactor waste (to be in operation by 1988), and an intermediate storage facility for vitrified high-level waste (to be in operation by 1990). The R and D activities are updated to September 1981

  8. ASME Code Efforts Supporting HTGRs

    Energy Technology Data Exchange (ETDEWEB)

    D.K. Morton

    2012-09-01

    In 1999, an international collaborative initiative for the development of advanced (Generation IV) reactors was started. The idea behind this effort was to bring nuclear energy closer to the needs of sustainability, to increase proliferation resistance, and to support concepts able to produce energy (both electricity and process heat) at competitive costs. The U.S. Department of Energy has supported this effort by pursuing the development of the Next Generation Nuclear Plant, a high temperature gas-cooled reactor. This support has included research and development of pertinent data, initial regulatory discussions, and engineering support of various codes and standards development. This report discusses the various applicable American Society of Mechanical Engineers (ASME) codes and standards that are being developed to support these high temperature gascooled reactors during construction and operation. ASME is aggressively pursuing these codes and standards to support an international effort to build the next generation of advanced reactors so that all can benefit.

  9. ASME Code Efforts Supporting HTGRs

    Energy Technology Data Exchange (ETDEWEB)

    D.K. Morton

    2011-09-01

    In 1999, an international collaborative initiative for the development of advanced (Generation IV) reactors was started. The idea behind this effort was to bring nuclear energy closer to the needs of sustainability, to increase proliferation resistance, and to support concepts able to produce energy (both electricity and process heat) at competitive costs. The U.S. Department of Energy has supported this effort by pursuing the development of the Next Generation Nuclear Plant, a high temperature gas-cooled reactor. This support has included research and development of pertinent data, initial regulatory discussions, and engineering support of various codes and standards development. This report discusses the various applicable American Society of Mechanical Engineers (ASME) codes and standards that are being developed to support these high temperature gascooled reactors during construction and operation. ASME is aggressively pursuing these codes and standards to support an international effort to build the next generation of advanced reactors so that all can benefit.

  10. Creating supportive nutrition environments for population health impact and health equity: an overview of the Nutrition and Obesity Policy Research and Evaluation Network's efforts.

    Science.gov (United States)

    Blanck, Heidi M; Kim, Sonia A

    2012-09-01

    Childhood obesity is a major threat to individual health and society overall. Policies that support healthier food and beverage choices have been endorsed by many decision makers. These policies may reach a large proportion of the population or in some circumstances aim to reduce nutrition disparities to ensure health equity. The Nutrition and Obesity Policy Research and Evaluation Network (NOPREN) evaluates policy as a tool to improve food and beverage environments where Americans live, work, play, and learn. The network aspires to address research and evaluation gaps related to relevant policies, create standardized research tools, and help build the evidence base of effective policy solutions for childhood obesity prevention with a focus on reach, equity, cost effectiveness, and sustainability. Published by Elsevier Inc.

  11. Dopamine, behavioral economics, and effort

    Directory of Open Access Journals (Sweden)

    John D Salamone

    2009-09-01

    Full Text Available Abstract. There are numerous problems with the hypothesis that brain dopamine (DA systems, particularly in the nucleus accumbens, directly mediate the rewarding or primary motivational characteristics of natural stimuli such as food. Research and theory related to the functions of mesolimbic DA are undergoing a substantial conceptual restructuring, with the traditional emphasis on hedonia and primary reward yielding to other concepts and lines of inquiry. The present review is focused upon the involvement of nucleus accumbens DA in behavioral activation and effort-related processes. Viewed from the framework of behavioral economics, the effects of accumbens DA depletions and antagonism on food-reinforced behavior are highly dependent upon the work requirements of the instrumental task, and DA depleted rats are more sensitive to increases in response costs (i.e., ratio requirements. Moreover, interference with accumbens DA transmission exerts a powerful influence over effort-related choice behavior. Rats with accumbens DA depletions or antagonism reallocate their instrumental behavior away from food-reinforced tasks that have high response requirements, and instead these rats select a less-effortful type of food-seeking behavior. Nucleus accumbens DA and adenosine interact in the regulation of effort-related functions, and other brain structures (anterior cingulate cortex, amygdala, ventral pallidum also are involved. Studies of the brain systems regulating effort-based processes may have implications for understanding drug abuse, as well as energy-related disorders such as psychomotor slowing, fatigue or anergia in depression and other neurological disorders.

  12. Reduced Delay of Gratification and Effortful Control among Young Children with Autism Spectrum Disorders

    Science.gov (United States)

    Faja, Susan; Dawson, Geraldine

    2015-01-01

    We explored internal control of behavior using direct observation and parent report. Previous research has found that both the delay of gratification task and parent-reported effortful control predict later social ability and more positive outcomes in typically developing children. Children with autism spectrum disorder have previously been…

  13. United States Department of Agriculture Forest Service 1996 annual report wetlands research related to the Pen Branch restoration effort on the Savannah River site

    Energy Technology Data Exchange (ETDEWEB)

    Nelson, E.A. [Westinghouse Savannah River Company, Aiken, SC (United States); Kolka, R.K. [USDA Forest Service, Charleston, SC (United States); Trettin, C.C. [USDA Forest Service, Charleston, SC (United States)

    1997-01-01

    This report documents the role of the USDA Forest Service and their collaborators (SRTC, SREL, and several universities) in wetlands monitoring and research on the Savannah River Site. This report describes the rationales, methods, and results (when available) of these studies and summarizes and integrates the available information through 1996.

  14. A case for the expansion of effort and the adoption of a modified approach in Australia to education and research on the engineering and technology of nuclear power

    International Nuclear Information System (INIS)

    Ford, G.W.K.

    1981-11-01

    A positive initiative needs to be taken to place more emphasis on undergraduate education in the field of nuclear engineering in Australia. Excellent facilities exist at the AAEC to aid tertiary institutions. Many excellent opportunities also exist for developing post-graduate research projects in nuclear technology

  15. Organization of research team for nano-associated safety assessment in effort to study nanotoxicology of zinc oxide and silica nanoparticles

    Directory of Open Access Journals (Sweden)

    Kim YR

    2014-12-01

    Full Text Available Yu-Ri Kim,1,* Sung Ha Park,2,* Jong-Kwon Lee,3 Jayoung Jeong,3 Ja Hei Kim,4 Eun-Ho Meang,5 Tae Hyun Yoon,6 Seok Tae Lim,7 Jae-Min Oh,8 Seong Soo A An,9 Meyoung-Kon Kim1 1Department of Biochemistry and Molecular Biology, Korea University Medical School and College, Seoul, South Korea; 2Department of Biochemistry, University of Bath, Bath, UK; 3Toxicological Research Division, National Institute of Food and Drug Safety Evaluation, Chungchungbuk-do, 4Consumers Korea, Chongro-ku, 5General toxicology team, Korea Testing and Research Institute, 6Laboratory of Nanoscale Characterization and Environmental Chemistry, Department of Chemistry, College of Natural Sciences, Hanyang University, Seoul, 7Department of Nuclear Medicine, Chonbuk National University Medical School, Jeonju, Jellabuk-Do, 8Department of Chemistry and Medical Chemistry, College of Science and Technology, Yonsei University, Gangwon-do, 9Department of Bionanotechnology, Gachon Medical Research Institute, Gachon University, Seongnam, South Korea *Authors contributed equally to this work Abstract: Currently, products made with nanomaterials are used widely, especially in biology, biotechnologies, and medical areas. However, limited investigations on potential toxicities of nanomaterials are available. Hence, diverse and systemic toxicological data with new methods for nanomaterials are needed. In order to investigate the nanotoxicology of nanoparticles (NPs, the Research Team for Nano-Associated Safety Assessment (RT-NASA was organized in three parts and launched. Each part focused on different contents of research directions: investigators in part I were responsible for the efficient management and international cooperation on nano-safety studies; investigators in part II performed the toxicity evaluations on target organs such as assessment of genotoxicity, immunotoxicity, or skin penetration; and investigators in part III evaluated the toxicokinetics of NPs with newly developed

  16. What role can child-care settings play in obesity prevention? A review of the evidence and call for research efforts.

    Science.gov (United States)

    Larson, Nicole; Ward, Dianne S; Neelon, Sara Benjamin; Story, Mary

    2011-09-01

    Given the widespread use of out-of-home child care and an all-time high prevalence of obesity among US preschool-aged children, it is imperative to consider the opportunities that child-care facilities may provide to reduce childhood obesity. This review examines the scientific literature on state regulations, practices and policies, and interventions for promoting healthy eating and physical activity, and for preventing obesity in preschool-aged children attending child care. Research published between January 2000 and July 2010 was identified by searching PubMed and MEDLINE databases, and by examining the bibliographies of relevant studies. Although the review focused on US child-care settings, interventions implemented in international settings were also included. In total, 42 studies were identified for inclusion in this review: four reviews of state regulations, 18 studies of child-care practices and policies that may influence eating or physical activity behaviors, two studies of parental perceptions and practices relevant to obesity prevention, and 18 evaluated interventions. Findings from this review reveal that most states lack strong regulations for child-care settings related to healthy eating and physical activity. Recent assessments of child-care settings suggest opportunities for improving the nutritional quality of food provided to children, the time children are engaged in physical activity, and caregivers' promotion of children's health behaviors and use of health education resources. A limited number of interventions have been designed to address these concerns, and only two interventions have successfully demonstrated an effect on child weight status. Recommendations are provided for future research addressing opportunities to prevent obesity in child-care settings. Copyright © 2011 American Dietetic Association. Published by Elsevier Inc. All rights reserved.

  17. Progress of JT-60SA Project: EU-JA joint efforts for assembly and fabrication of superconducting tokamak facilities and its research planning

    Energy Technology Data Exchange (ETDEWEB)

    Shirai, Hiroshi, E-mail: shirai.hiroshi@jaea.go.jp [JT-60SA Project Team, Japan Atomic Energy Agency, 801-1 Mukoyama, Naka, Ibaraki 311-0193 (Japan); Barabaschi, Pietro [JT-60SA EU-Home Team, Fusion for Energy, Boltsmannstr 2, Garching 85748 (Germany); Kamada, Yutaka [JT-60SA JA-Home Team, Japan Atomic Energy Agency, 801-1 Mukoyama, Naka, Ibaraki 311-0193 (Japan)

    2016-11-01

    Highlights: • JT-60SA Project is promoted under the BA Agreement and JA national programme. • JT-60SA is designed to operate in break-even equivalent condition for a long period. • JT-60SA Project supports and complements the ITER project, and promotes DEMO design. • Fabrication of JT-60SA components and assembly in Naka are steadily going on. • JT-60SA Research Plan has been developed jointly by EU and JA fusion communities. - Abstract: Aiming at supporting the early realization of fusion energy, the JT-60SA Project has shown steady progress for several years toward the first plasma in 2019 under the dual frameworks: the Satellite Tokamak Programme of the Broader Approach Agreement between EU and Japan, and the Japanese national programme. JT-60SA is a superconducting tokamak designed to operate in break-even equivalent conditions for a long pulse duration (typically 100 s) with a maximum plasma current of 5.5 MA. A variety of plasma control capabilities enable JT-60SA to contribute directly to the ITER project and also to DEMO by addressing key engineering and physics issues for advanced plasma operation. Design and fabrication of JT-60SA components, shared by the EU and Japan, started in 2007. Assembly in the torus hall started in January 2013, and welding work of the vacuum vessel sectors (seven 40° sectors and two 30° sectors) is currently ongoing on the cryostat base. Other components such as TF coils, PF coils, power supplies, cryogenic system, cryostat vessel, thermal shields and so on were or are being delivered to the Naka site for installation, assembly and commissioning. This paper gives technical progress on fabrication, installation and assembly of tokamak components and ancillary systems, as well as progress of the JT-60SA Research Plan being developed jointly by European and Japanese fusion communities.

  18. A survey of previous and current industry-wide efforts regarding burnup credit

    International Nuclear Information System (INIS)

    Jones, R.H.

    1989-01-01

    Sandia has examined the matter of burnup credit from the perspective of physics, logistics, risk, and economics. A limited survey of the nuclear industry has been conducted to get a feeling for the actual application of burnup credit. Based on this survey, it can be concluded that the suppliers of spent fuel storage and transport casks are in general agreement that burnup credit offers the potential for improvements in cask efficiency without increasing the risk of accidental criticality. The actual improvement is design-specific but limited applications have demonstrated that capacity increases in the neighborhood of 20 percent are not unrealistic. A number of these vendors acknowledge that burnup credit has not been reduced to practice in cask applications and suggest that operational considerations may be more important to regulatory acceptance than to the physics. Nevertheless, the importance of burnup credit to the nuclear industry as a cask design and analysis tool has been confirmed by this survey

  19. Enhancing atmospheric mercury research in China to improve the current understanding of the global mercury cycle: the need for urgent and closely coordinated efforts.

    Science.gov (United States)

    Ci, Zhijia; Zhang, Xiaoshan; Wang, Zhangwei

    2012-06-05

    The current understanding of the global mercury (Hg) cycle remains uncertain because Hg behavior in the environment is very complicated. The special property of Hg causes the atmosphere to be the most important medium for worldwide dispersion and transformation. The source and fate of atmospheric Hg and its interaction with the surface environment are the essential topics in the global Hg cycle. Recent declining measurement trends of Hg in the atmosphere are in apparent conflict with the increasing trends in global anthropogenic Hg emissions. As the single largest country contributor of anthropogenic Hg emission, China's role in the global Hg cycle will become more and more important in the context of the decreasing man-made Hg emission from developed regions. However, much less Hg information in China is available. As a global pollutant which undergoes long-range transport and is persistence in the environment, increasing Hg knowledge in China could not only promote the Hg regulation in this country but also improve the understanding of the fundamental of the global Hg cycle and further push the abatement of this toxin on a global scale. Then the atmospheric Hg research in China may be a breakthrough for improving the current understanding of the global Hg cycle. However, due to the complex behavior of Hg in the atmosphere, a deeper understanding of the atmospheric Hg cycle in China needs greater cooperation across fields.

  20. CHEMICAL EFFECTS ON PWR SUMP STRAINER BLOCKAGE AFTER A LOSS-OF-COOLANT ACCIDENT: REVIEW ON U.S. RESEARCH EFFORTS

    Directory of Open Access Journals (Sweden)

    CHI BUM BAHN

    2013-06-01

    Full Text Available Industry- or regulatory-sponsored research activities on the resolution of Generic Safety Issue (GSI-191 were reviewed, especially on the chemical effects. Potential chemical effects on the head loss across the debris-loaded sump strainer under a post-accident condition were experimentally evidenced by small-scale bench tests, integrated chemical effects test (ICET, and vertical loop head loss tests. Three main chemical precipitates were identified by WCAP-16530-NP: calcium phosphate, aluminum oxyhydroxide, and sodium aluminum silicate. The former two precipitates were also identified as major chemical precipitates by the ICETs. The assumption that all released calcium would form precipitates is reasonable. CalSil insulation needs to be minimized especially in a plant using trisodium phosphate buffer. The assumption that all released aluminum would form precipitates appears highly conservative because ICETs and other studies suggest substantial solubility of aluminum at high temperature and inhibition of aluminum corrosion by silicate or phosphate. The industry-proposed chemical surrogates are quite effective in increasing the head loss across the debris-loaded bed and more effective than the prototypical aluminum hydroxide precipitates generated by in-situ aluminum corrosion. There appears to be some unresolved potential issues related to GSI-191 chemical effects as identified in NUREG/CR-6988. The United States Nuclear Regulatory Commission, however, concluded that the implications of these issues are either not generically significant or are appropriately addressed, although several issues associated with downstream in-vessel effects remain.

  1. Comparison of practice based research network based quality improvement technical assistance and evaluation to other ongoing quality improvement efforts for changes in agency culture.

    Science.gov (United States)

    Livingood, William C; Peden, Angela H; Shah, Gulzar H; Marshall, Nandi A; Gonzalez, Ketty M; Toal, Russell B; Alexander, Dayna S; Wright, Alesha R; Woodhouse, Lynn D

    2015-07-31

    Public health agencies in the USA are increasingly challenged to adopt Quality Improvement (QI) strategies to enhance performance. Many of the functional and structural barriers to effective use of QI can be found in the organizational culture of public health agencies. The purpose of this study was to assess the impact of public health practice based research network (PBRN) evaluation and technical assistance for QI interventions on the organizational culture of public health agencies in Georgia, USA. An online survey of key informants in Georgia's districts and county health departments was used to compare perceptions of characteristics of organizational QI culture between PBRN supported QI districts and non-PBRN supported districts before and after the QI interventions. The primary outcomes of concern were number and percentage of reported increases in characteristics of QI culture as measured by key informant responses to items assessing organizational QI practices from a validated instrument on QI Collaboratives. Survey results were analyzed using Multi-level Mixed Effects Logistic Model, which accounts for clustering/nesting. Increases in QI organizational culture were consistent for all 10- items on a QI organizational culture survey related to: leadership support, use of data, on-going QI, and team collaboration. Statistically significant odds ratios were calculated for differences in increased QI organizational culture between PBRN-QI supported districts compared to Non-PBRN supported districts for 5 of the 10 items, after adjusting for District clustering of county health departments. Agency culture, considered by many QI experts as the main goal of QI, is different than use of specific QI methods, such as Plan-Do-Study-Act (PDSA) cycles or root-cause analyses. The specific use of a QI method does not necessarily reflect culture change. Attempts to measure QI culture are newly emerging. This study documented significant improvements in characteristics of

  2. Current research efforts with Bacillus thuringiensis

    Science.gov (United States)

    Normand R. Dubois

    1991-01-01

    The bioassay of 260 strains of Bacillus thuringiensis (Bt) and 70 commercial preparations show that regression coefficient estimates may be as critical as LC5O estimates when evaluating them for future consideration.

  3. Literality and Cognitive Effort

    DEFF Research Database (Denmark)

    Lacruz, Isabel; Carl, Michael; Yamada, Masaru

    2018-01-01

    We introduce a notion of pause-word ratio computed using ranges of pause lengths rather than lower cutoffs for pause lengths. Standard pause-word ratios are indicators of cognitive effort during different translation modalities.The pause range version allows for the study of how different types...... remoteness. We use data from the CRITT TPR database, comparing translation and post-editing from English to Japanese and from English to Spanish, and study the interaction of pause-word ratio for short pauses ranging between 300 and 500ms with syntactic remoteness, measured by the CrossS feature, semantic...... remoteness, measured by HTra, and syntactic and semantic remoteness, measured by Literality....

  4. Breckinridge Project, initial effort

    Energy Technology Data Exchange (ETDEWEB)

    None, None

    1982-09-01

    Report III, Volume 1 contains those specifications numbered A through J, as follows: General Specifications (A); Specifications for Pressure Vessels (C); Specifications for Tanks (D); Specifications for Exchangers (E); Specifications for Fired Heaters (F); Specifications for Pumps and Drivers (G); and Specifications for Instrumentation (J). The standard specifications of Bechtel Petroleum Incorporated have been amended as necessary to reflect the specific requirements of the Breckinridge Project, and the more stringent specifications of Ashland Synthetic Fuels, Inc. These standard specifications are available to the Initial Effort (Phase Zero) work performed by all contractors and subcontractors. Report III, Volume 1 also contains the unique specifications prepared for Plants 8, 15, and 27. These specifications will be substantially reviewed during Phase I of the project, and modified as necessary for use during the engineering, procurement, and construction of this project.

  5. Mapping telemedicine efforts

    DEFF Research Database (Denmark)

    Kierkegaard, Patrick

    2015-01-01

    are being utilized? What medical disciplines are being addressed using telemedicine systems? Methods: All data was surveyed from the "Telemedicinsk Landkort", a newly created database designed to provide a comprehensive and systematic overview of all telemedicine technologies in Denmark. Results......Objectives: The aim of this study is to survey telemedicine services currently in operation across Denmark. The study specifically seeks to answer the following questions: What initiatives are deployed within the different regions? What are the motivations behind the projects? What technologies......: The results of this study suggest that a growing number of telemedicine initiatives are currently in operation across Denmark but that considerable variations existed in terms of regional efforts as the number of operational telemedicine projects varied from region to region. Conclusions: The results...

  6. Motivation and effort in individuals with social anhedonia.

    Science.gov (United States)

    McCarthy, Julie M; Treadway, Michael T; Blanchard, Jack J

    2015-06-01

    It has been proposed that anhedonia may, in part, reflect difficulties in reward processing and effortful decision making. The current study aimed to replicate previous findings of effortful decision making deficits associated with elevated anhedonia and expand upon these findings by investigating whether these decision making deficits are specific to elevated social anhedonia or are also associated with elevated positive schizotypy characteristics. The current study compared controls (n=40) to individuals elevated on social anhedonia (n=30), and individuals elevated on perceptual aberration/magical ideation (n=30) on the Effort Expenditure for Rewards Task (EEfRT). Across groups, participants chose a higher proportion of hard tasks with increasing probability of reward and reward magnitude, demonstrating sensitivity to probability and reward values. Contrary to our expectations, when the probability of reward was most uncertain (50% probability), at low and medium reward values, the social anhedonia group demonstrated more effortful decision making than either individuals high in positive schizotypy or controls. The positive schizotypy group only differed from controls (making less effortful choices than controls) when reward probability was lowest (12%) and the magnitude of reward was the smallest. Our results suggest that social anhedonia is related to intact motivation and effort for monetary rewards, but that individuals with this characteristic display a unique and perhaps inefficient pattern of effort allocation when the probability of reward is most uncertain. Future research is needed to better understand effortful decision making and the processing of reward across a range of individual difference characteristics. Copyright © 2015 Elsevier B.V. All rights reserved.

  7. Previously unknown species of Aspergillus.

    Science.gov (United States)

    Gautier, M; Normand, A-C; Ranque, S

    2016-08-01

    The use of multi-locus DNA sequence analysis has led to the description of previously unknown 'cryptic' Aspergillus species, whereas classical morphology-based identification of Aspergillus remains limited to the section or species-complex level. The current literature highlights two main features concerning these 'cryptic' Aspergillus species. First, the prevalence of such species in clinical samples is relatively high compared with emergent filamentous fungal taxa such as Mucorales, Scedosporium or Fusarium. Second, it is clearly important to identify these species in the clinical laboratory because of the high frequency of antifungal drug-resistant isolates of such Aspergillus species. Matrix-assisted laser desorption/ionization-time of flight mass spectrometry (MALDI-TOF MS) has recently been shown to enable the identification of filamentous fungi with an accuracy similar to that of DNA sequence-based methods. As MALDI-TOF MS is well suited to the routine clinical laboratory workflow, it facilitates the identification of these 'cryptic' Aspergillus species at the routine mycology bench. The rapid establishment of enhanced filamentous fungi identification facilities will lead to a better understanding of the epidemiology and clinical importance of these emerging Aspergillus species. Based on routine MALDI-TOF MS-based identification results, we provide original insights into the key interpretation issues of a positive Aspergillus culture from a clinical sample. Which ubiquitous species that are frequently isolated from air samples are rarely involved in human invasive disease? Can both the species and the type of biological sample indicate Aspergillus carriage, colonization or infection in a patient? Highly accurate routine filamentous fungi identification is central to enhance the understanding of these previously unknown Aspergillus species, with a vital impact on further improved patient care. Copyright © 2016 European Society of Clinical Microbiology and

  8. A Concentrated Effort

    Science.gov (United States)

    Lum, Lydia

    2010-01-01

    For years, New York health-care providers have treated Asian-Americans afflicted by serious, even life-threatening illnesses with ever-increasing frequency. Many doctors in the nation's largest city agreed that Asians seemed particularly at risk for specific health problems, but there was neither research nor statistics supporting physician…

  9. Worldwide effort against smoking.

    Science.gov (United States)

    1986-07-01

    The 39th World Health Assembly, which met in May 1986, recognized the escalating health problem of smoking-related diseases and affirmed that tobacco smoking and its use in other forms are incompatible with the attainment of "Health for All by the Year 2000." If properly implemented, antismoking campaigns can decrease the prevalence of smoking. Nations as a whole must work toward changing smoking habits, and governments must support these efforts by officially stating their stand against smoking. Over 60 countries have introduced legislation affecting smoking. The variety of policies range from adopting a health education program designed to increase peoples' awareness of its dangers to increasing taxes to deter smoking by increasing tobacco prices. Each country must adopt an antismoking campaign which works most effectively within the cultural parameters of the society. Other smoking policies include: printed warnings on cigarette packages; health messages via radio, television, mobile teams, pamphlets, health workers, clinic walls, and newspapers; prohibition of smoking in public areas and transportation; prohibition of all advertisement of cigarettes and tobacco; and the establishment of upper limits of tar and nicotine content in cigarettes. The tobacco industry spends about $2000 million annually on worldwide advertising. According to the World Health Organization (WHO), controlling this overabundance of tobacco advertisements is a major priority in preventing the spread of smoking. Cigarette and tobacco advertising can be controlled to varying degrees, e.g., over a dozen countries have enacted a total ban on advertising on television or radio, a mandatory health warning must accompany advertisements in other countries, and tobacco companies often are prohibited from sponsoring sports events. Imposing a substantial tax on cigarettes is one of the most effective means to deter smoking. However, raising taxes and banning advertisements is not enough because

  10. Fiscal 1998 research report. Survey on the current trend of private R and D efforts; 1998 nendo chosa hokokusho. Minkan no kenkyu kaihatsu doko no jittai ni kansuru chosa

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-03-01

    For promotion of the R and D system of technologies creating new industries, this survey collected the basic data and information on the trend of private R and D efforts and industries, and arranged every data and information obtained. The data on United States, Germany, France and U.K. in addition to Japan were collected. Survey was made first on the administrative support system for private R and D efforts. The R and D-related budget, R and D support program and private R and D-related fund of Japan, United States and U.K. are mainly outlined. Survey was made next on private R and D activities. The R and D-related fund, researcher and patent of main countries are outlined in international comparison. Survey was also made on the current state of various industries. The industry scale and structure of every Japanese manufacturing industry are outlined. Finally, the industrial statistics are given concerning Japanese 'chemical industry,' 'communication-electronics-electric measuring instrument industry' and 'automobile industry' with a high rate of R and D-related expenditures. (NEDO)

  11. The Effort Paradox: Effort Is Both Costly and Valued.

    Science.gov (United States)

    Inzlicht, Michael; Shenhav, Amitai; Olivola, Christopher Y

    2018-04-01

    According to prominent models in cognitive psychology, neuroscience, and economics, effort (be it physical or mental) is costly: when given a choice, humans and non-human animals alike tend to avoid effort. Here, we suggest that the opposite is also true and review extensive evidence that effort can also add value. Not only can the same outcomes be more rewarding if we apply more (not less) effort, sometimes we select options precisely because they require effort. Given the increasing recognition of effort's role in motivation, cognitive control, and value-based decision-making, considering this neglected side of effort will not only improve formal computational models, but also provide clues about how to promote sustained mental effort across time. Copyright © 2018 Elsevier Ltd. All rights reserved.

  12. Cognitive Load and Listening Effort: Concepts and Age-Related Considerations.

    Science.gov (United States)

    Lemke, Ulrike; Besser, Jana

    2016-01-01

    Listening effort has been recognized as an important dimension of everyday listening, especially with regard to the comprehension of spoken language. At constant levels of comprehension performance, the level of effort exerted and perceived during listening can differ considerably across listeners and situations. In this article, listening effort is used as an umbrella term for two different types of effort that can arise during listening. One of these types is processing effort, which is used to denote the utilization of "extra" mental processing resources in listening conditions that are adverse for an individual. A conceptual description is introduced how processing effort could be defined in terms of situational influences, the listener's auditory and cognitive resources, and the listener's personal state. Also, the proposed relationship between processing effort and subjectively perceived listening effort is discussed. Notably, previous research has shown that the availability of mental resources, as well as the ability to use them efficiently, changes over the course of adult aging. These common age-related changes in cognitive abilities and their neurocognitive organization are discussed in the context of the presented concept, especially regarding situations in which listening effort may be increased for older people.

  13. Research

    African Journals Online (AJOL)

    abp

    2016-02-01

    Feb 1, 2016 ... University Hospital, DK-5000 Odense, Denmark, 3Center for Global Health, Institute of Clinical Research, University of Southern Denmark, DK-5000. Odense .... BHP is a Danish-Guinean Demographic Surveillance Site with a study-area .... variables such as age groups, previous military duty, history of.

  14. Research

    African Journals Online (AJOL)

    abp

    2015-06-24

    Jun 24, 2015 ... related immunosuppression, previous history of TB, and pause in treatment [6]. In Brazil, researchers .... treatment, use of traditional medicines or herbs, history of TB drug side effects and treatment delay). ..... therapy for pulmonary tuberculosis in Lima Ciudad, Peru. International journal of tuberculosis and ...

  15. Subsequent childbirth after a previous traumatic birth.

    Science.gov (United States)

    Beck, Cheryl Tatano; Watson, Sue

    2010-01-01

    Nine percent of new mothers in the United States who participated in the Listening to Mothers II Postpartum Survey screened positive for meeting the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition criteria for posttraumatic stress disorder after childbirth. Women who have had a traumatic birth experience report fewer subsequent children and a longer length of time before their second baby. Childbirth-related posttraumatic stress disorder impacts couples' physical relationship, communication, conflict, emotions, and bonding with their children. The purpose of this study was to describe the meaning of women's experiences of a subsequent childbirth after a previous traumatic birth. Phenomenology was the research design used. An international sample of 35 women participated in this Internet study. Women were asked, "Please describe in as much detail as you can remember your subsequent pregnancy, labor, and delivery following your previous traumatic birth." Colaizzi's phenomenological data analysis approach was used to analyze the stories of the 35 women. Data analysis yielded four themes: (a) riding the turbulent wave of panic during pregnancy; (b) strategizing: attempts to reclaim their body and complete the journey to motherhood; (c) bringing reverence to the birthing process and empowering women; and (d) still elusive: the longed-for healing birth experience. Subsequent childbirth after a previous birth trauma has the potential to either heal or retraumatize women. During pregnancy, women need permission and encouragement to grieve their prior traumatic births to help remove the burden of their invisible pain.

  16. Rapid fish stock depletion in previously unexploited seamounts: the ...

    African Journals Online (AJOL)

    Rapid fish stock depletion in previously unexploited seamounts: the case of Beryx splendens from the Sierra Leone Rise (Gulf of Guinea) ... A spectral analysis and red-noise spectra procedure (REDFIT) algorithm was used to identify the red-noise spectrum from the gaps in the observed time-series of catch per unit effort by ...

  17. Multidisciplinary Efforts Driving Translational Theranostics

    Science.gov (United States)

    Hu, Tony Y.

    2014-01-01

    This themed issue summarizes significant efforts aimed at using “biological language” to discern between “friends” and “foes” in the context of theranostics for true clinical application. It is expected that the success of theranostics depends on multidisciplinary efforts, combined to expedite our understanding of host responses to “customized” theranostic agents and formulating individualized therapies. PMID:25285169

  18. Learning Environment and Student Effort

    Science.gov (United States)

    Hopland, Arnt O.; Nyhus, Ole Henning

    2016-01-01

    Purpose: The purpose of this paper is to explore the relationship between satisfaction with learning environment and student effort, both in class and with homework assignments. Design/methodology/approach: The authors use data from a nationwide and compulsory survey to analyze the relationship between learning environment and student effort. The…

  19. Respiratory effort from the photoplethysmogram.

    Science.gov (United States)

    Addison, Paul S

    2017-03-01

    The potential for a simple, non-invasive measure of respiratory effort based on the pulse oximeter signal - the photoplethysmogram or 'pleth' - was investigated in a pilot study. Several parameters were developed based on a variety of manifestations of respiratory effort in the signal, including modulation changes in amplitude, baseline, frequency and pulse transit times, as well as distinct baseline signal shifts. Thirteen candidate parameters were investigated using data from healthy volunteers. Each volunteer underwent a series of controlled respiratory effort maneuvers at various set flow resistances and respiratory rates. Six oximeter probes were tested at various body sites. In all, over three thousand pleth-based effort-airway pressure (EP) curves were generated across the various airway constrictions, respiratory efforts, respiratory rates, subjects, probe sites, and the candidate parameters considered. Regression analysis was performed to determine the existence of positive monotonic relationships between the respiratory effort parameters and resulting airway pressures. Six of the candidate parameters investigated exhibited a distinct positive relationship (poximeter probe and an ECG (P2E-Effort) and the other using two pulse oximeter probes placed at different peripheral body sites (P2-Effort); and baseline shifts in heart rate, (BL-HR-Effort). In conclusion, a clear monotonic relationship was found between several pleth-based parameters and imposed respiratory loadings at the mouth across a range of respiratory rates and flow constrictions. The results suggest that the pleth may provide a measure of changing upper airway dynamics indicative of the effort to breathe. Copyright © 2017 The Author. Published by Elsevier Ltd.. All rights reserved.

  20. Understanding the Association Between Negative Symptoms and Performance on Effort-Based Decision-Making Tasks: The Importance of Defeatist Performance Beliefs.

    Science.gov (United States)

    Reddy, L Felice; Horan, William P; Barch, Deanna M; Buchanan, Robert W; Gold, James M; Marder, Stephen R; Wynn, Jonathan K; Young, Jared; Green, Michael F

    2017-11-13

    Effort-based decision-making paradigms are increasingly utilized to gain insight into the nature of motivation deficits. Research has shown associations between effort-based decision making and experiential negative symptoms; however, the associations are not consistent. The current study had two primary goals. First, we aimed to replicate previous findings of a deficit in effort-based decision making among individuals with schizophrenia on a test of cognitive effort. Second, in a large sample combined from the current and a previous study, we sought to examine the association between negative symptoms and effort by including the related construct of defeatist beliefs. The results replicated previous findings of impaired cognitive effort-based decision making in schizophrenia. Defeatist beliefs significantly moderated the association between negative symptoms and effort-based decision making such that there was a strong association between high negative symptoms and deficits in effort-based decision making, but only among participants with high levels of defeatist beliefs. Thus, our findings suggest the relationship between negative symptoms and effort performance may be understood by taking into account the role of defeatist beliefs, and finding that might explain discrepancies in previous studies. Published by Oxford University Press on behalf of the Maryland Psychiatric Research Center 2017.

  1. Hydrogen economy: a little bit more effort

    International Nuclear Information System (INIS)

    Pauron, M.

    2008-01-01

    In few years, the use of hydrogen in economy has become a credible possibility. Today, billions of euros are invested in the hydrogen industry which is strengthened by technological advances in fuel cells development and by an increasing optimism. However, additional research efforts and more financing will be necessary to make the dream of an hydrogen-based economy a reality

  2. Pandemic Influenza: Domestic Preparedness Efforts

    National Research Council Canada - National Science Library

    Lister, Sarah A

    2005-01-01

    .... Though influenza pandemics occur with some regularity, and the United States has been involved in specific planning efforts since the early 1990s, the H5N1 situation has created a sense of urgency...

  3. Effort Estimation in BPMS Migration

    OpenAIRE

    Drews, Christopher; Lantow, Birger

    2018-01-01

    Usually Business Process Management Systems (BPMS) are highly integrated in the IT of organizations and are at the core of their business. Thus, migrating from one BPMS solution to another is not a common task. However, there are forces that are pushing organizations to perform this step, e.g. maintenance costs of legacy BPMS or the need for additional functionality. Before the actual migration, the risk and the effort must be evaluated. This work provides a framework for effort estimation re...

  4. Hiding effort to gain a competitive advantage: Evidence from China.

    Science.gov (United States)

    Zhao, Li; Heyman, Gail D

    2018-06-01

    Previous studies with Western populations have shown that adolescents' tendency to downplay their academic effort is affected by two kinds of motives: ability-related motives (e.g., to appear competent) and social approval motives (e.g., to be popular). In this research, we test for the presence of additional competition-related motives in China, a culture placing strong emphasis on academic competition. Study 1 (N = 150) showed that, in response to a scenario in which a hard-working high-school junior hid effort from classmates, the most highly endorsed explanation was "to influence others to work less hard to maintain a competitive advantage." Study 2 (N = 174) revealed that competition-related explanations were endorsed relatively more often when the speaker and audience had similar academic rankings. This tendency was most evident when both speaker and audience were top performers, and when this was the case, participants' desire to demonstrate superiority over others was a positive predictor of endorsement of competition-related motives. Study 3 (N = 137) verified that competition-related motives were more strongly endorsed among Chinese participants than U.S. These results suggest that at least in cultures that emphasize academic competition and in contexts where competition is salient, hiding effort is often about attempting to gain strategic advantage. © 2016 International Union of Psychological Science.

  5. ON MIND MAPS: PREVIOUS IDEAS TO A RESEARCH PROPOUSAL

    Directory of Open Access Journals (Sweden)

    Javier Flórez Miranda

    2011-05-01

    Full Text Available Después de un diagnóstico poco alentador sobre las competencias lecto-escritoras de los estudiantes, fenómeno al que llama: ";Síndrome del pensamiento inmaduro";, el autor propone el uso de los llamados ";signos-herramienta"; de la teoría socio-cultural de Vigotsky. Con base en sus ideas, acerca de la posibilidad de utilizar vías de rodeo para superar algunas dificultades cognitivas de los estudiantes, propone la herramienta de los mapas mentales, cuya eficacia ha probado, durante su práctica docente.

  6. Effort Estimation in BPMS Migration

    Directory of Open Access Journals (Sweden)

    Christopher Drews

    2018-04-01

    Full Text Available Usually Business Process Management Systems (BPMS are highly integrated in the IT of organizations and are at the core of their business. Thus, migrating from one BPMS solution to another is not a common task. However, there are forces that are pushing organizations to perform this step, e.g. maintenance costs of legacy BPMS or the need for additional functionality. Before the actual migration, the risk and the effort must be evaluated. This work provides a framework for effort estimation regarding the technical aspects of BPMS migration. The framework provides questions for BPMS comparison and an effort evaluation schema. The applicability of the framework is evaluated based on a simplified BPMS migration scenario.

  7. Effort problem of chemical pipelines

    Energy Technology Data Exchange (ETDEWEB)

    Okrajni, J.; Ciesla, M.; Mutwil, K. [Silesian Technical University, Katowice (Poland)

    1998-12-31

    The problem of the technical state assessment of the chemical pipelines working under mechanical and thermal loading has been shown in the paper. The pipelines effort after the long time operating period has been analysed. Material geometrical and loading conditions of the crack initiation and crack growth process in the chosen object has been discussed. Areas of the maximal effort have been determined. The material structure charges after the long time operating period have been described. Mechanisms of the crack initiation and crack growth in the pipeline elements have been analysed and mutual relations between the chemical and mechanical influences have been shown. (orig.) 16 refs.

  8. Learner Characteristic Based Learning Effort Curve Mode: The Core Mechanism on Developing Personalized Adaptive E-Learning Platform

    Science.gov (United States)

    Hsu, Pi-Shan

    2012-01-01

    This study aims to develop the core mechanism for realizing the development of personalized adaptive e-learning platform, which is based on the previous learning effort curve research and takes into account the learner characteristics of learning style and self-efficacy. 125 university students from Taiwan are classified into 16 groups according…

  9. Reproductive effort in viscous populations

    NARCIS (Netherlands)

    Pen, Ido

    Here I study a kin selection model of reproductive effort, the allocation of resources to fecundity versus survival, in a patch-structured population. Breeding females remain in the same patch for life. Offspring have costly, partial long-distance dispersal and compete for breeding sites, which

  10. Environmental Determinants of Lexical Processing Effort

    OpenAIRE

    McDonald, Scott

    2000-01-01

    Institute for Adaptive and Neural Computation A central concern of psycholinguistic research is explaining the relative ease or difficulty involved in processing words. In this thesis, we explore the connection between lexical processing effort and measurable properties of the linguistic environment. Distributional information (information about a word’s contexts of use) is easily extracted from large language corpora in the form of co-occurrence statistics. We claim that su...

  11. IAEA Patient Protection Effort Reaches Key Milestone

    International Nuclear Information System (INIS)

    2012-01-01

    Full text: An International Atomic Energy Agency (IAEA) effort to help people track their radiation exposure from medical procedures achieved a significant milestone this week. The Agency received the final approval from a group of medical oversight organizations for the 'Joint Position Statement on the IAEA Patient Radiation Exposure Tracking', a set of principles to guide patient protection efforts at the sub-national, national, and international level. The joint statement endorses the IAEA's three-year-old Smart Card/SmartRadTrack project, which aims to help nations develop systems to track medical radiation procedures and radiation doses. The statement has been agreed by the World Health Organization (WHO), the U.S. Food and Drug Administration (FDA), the European Society of Radiology (ESR), the International Organization for Medical Physics (IOMP), the International Society of Radiographers and Radiological Technologists (ISRRT), and the Conference of Radiation Control Program Directors, USA (CRCPD). 'This system is critical if the medical community is going to keep patients safe when they are being referred for more and more diagnostic scans. These scans, over the years, are made using more and more powerful machines', said Madan Rehani, Radiation Safety Specialist in the IAEA's Radiation Protection of Patients Unit. 'The tracking system will draw doctors' attention to previous radiological examinations, both in terms of clinical information and radiation dose and thus help them assess whether the 11th or 20th CT scan is really appropriate, whether it will do more good than harm.' Advances in radiation-based diagnostic technologies, such as the CT scan, have led to patients receiving such procedures more frequently. The convenience of CT with the added advantage of increased information has resulted in increased usage to the point that there are instances of patients getting tens of CT scans in a few years, not all of which may be justified, or getting CT

  12. Toward a Rational and Mechanistic Account of Mental Effort.

    Science.gov (United States)

    Shenhav, Amitai; Musslick, Sebastian; Lieder, Falk; Kool, Wouter; Griffiths, Thomas L; Cohen, Jonathan D; Botvinick, Matthew M

    2017-07-25

    In spite of its familiar phenomenology, the mechanistic basis for mental effort remains poorly understood. Although most researchers agree that mental effort is aversive and stems from limitations in our capacity to exercise cognitive control, it is unclear what gives rise to those limitations and why they result in an experience of control as costly. The presence of these control costs also raises further questions regarding how best to allocate mental effort to minimize those costs and maximize the attendant benefits. This review explores recent advances in computational modeling and empirical research aimed at addressing these questions at the level of psychological process and neural mechanism, examining both the limitations to mental effort exertion and how we manage those limited cognitive resources. We conclude by identifying remaining challenges for theoretical accounts of mental effort as well as possible applications of the available findings to understanding the causes of and potential solutions for apparent failures to exert the mental effort required of us.

  13. Efforts to Improve Writing Skills of High School Students

    Directory of Open Access Journals (Sweden)

    Nurul Inayah

    2016-03-01

    Full Text Available Writing in English is one of the language skills that are taught in the context of learning English as a Foreign Language (EFL in Indonesian senior high schools. According to previous studies, most of the students consider writing is the most difficult of the four skills. This research was aimed at finding out the main difficulties in writing faced by the grade XI students at SMA Negeri 10 Fajar Harapan, Banda Aceh, and the efforts made by their teacher to overcome those problems. The design of this study was a descriptive qualitative study. To obtain the data, the writers used document collection and interviews. The results from the document collection showed that the highest percentages of problems faced by the students were in the aspect of language use and the least problems were in the aspect of content. The results from the interviews showed that the most common correcting efforts made by the teacher were giving written feedback for all aspects of writing i.e. language use, mechanics, vocabulary, organization, and content. Likewise, teachers need to develop systemized forms of feedback and make it clear to students what the feedback means and what they are to do with them to assist students in improving their writing skills.

  14. Voluntary versus Enforced Team Effort

    Directory of Open Access Journals (Sweden)

    Claudia Keser

    2011-08-01

    Full Text Available We present a model where each of two players chooses between remuneration based on either private or team effort. Although at least one of the players has the equilibrium strategy to choose private remuneration, we frequently observe both players to choose team remuneration in a series of laboratory experiments. This allows for high cooperation payoffs but also provides individual free-riding incentives. Due to significant cooperation, we observe that, in team remuneration, participants make higher profits than in private remuneration. We also observe that, when participants are not given the option of private remuneration, they cooperate significantly less.

  15. Preoperative screening: value of previous tests.

    Science.gov (United States)

    Macpherson, D S; Snow, R; Lofgren, R P

    1990-12-15

    To determine the frequency of tests done in the year before elective surgery that might substitute for preoperative screening tests and to determine the frequency of test results that change from a normal value to a value likely to alter perioperative management. Retrospective cohort analysis of computerized laboratory data (complete blood count, sodium, potassium, and creatinine levels, prothrombin time, and partial thromboplastin time). Urban tertiary care Veterans Affairs Hospital. Consecutive sample of 1109 patients who had elective surgery in 1988. At admission, 7549 preoperative tests were done, 47% of which duplicated tests performed in the previous year. Of 3096 previous results that were normal as defined by hospital reference range and done closest to the time of but before admission (median interval, 2 months), 13 (0.4%; 95% CI, 0.2% to 0.7%), repeat values were outside a range considered acceptable for surgery. Most of the abnormalities were predictable from the patient's history, and most were not noted in the medical record. Of 461 previous tests that were abnormal, 78 (17%; CI, 13% to 20%) repeat values at admission were outside a range considered acceptable for surgery (P less than 0.001, frequency of clinically important abnormalities of patients with normal previous results with those with abnormal previous results). Physicians evaluating patients preoperatively could safely substitute the previous test results analyzed in this study for preoperative screening tests if the previous tests are normal and no obvious indication for retesting is present.

  16. Analysis Efforts Supporting NSTX Upgrades

    International Nuclear Information System (INIS)

    Zhang, H.; Titus, P.; Rogoff, P.; Zolfaghari, A.; Mangra, D.; Smith, M.

    2010-01-01

    The National Spherical Torus Experiment (NSTX) is a low aspect ratio, spherical torus (ST) configuration device which is located at Princeton Plasma Physics Laboratory (PPPL) This device is presently being updated to enhance its physics by doubling the TF field to 1 Tesla and increasing the plasma current to 2 Mega-amperes. The upgrades include a replacement of the centerstack and addition of a second neutral beam. The upgrade analyses have two missions. The first is to support design of new components, principally the centerstack, the second is to qualify existing NSTX components for higher loads, which will increase by a factor of four. Cost efficiency was a design goal for new equipment qualification, and reanalysis of the existing components. Showing that older components can sustain the increased loads has been a challenging effort in which designs had to be developed that would limit loading on weaker components, and would minimize the extent of modifications needed. Two areas representing this effort have been chosen to describe in more details: analysis of the current distribution in the new TF inner legs, and, second, analysis of the out-of-plane support of the existing TF outer legs.

  17. APS Education and Diversity Efforts

    Science.gov (United States)

    Prestridge, Katherine; Hodapp, Theodore

    2015-11-01

    American Physical Society (APS) has a wide range of education and diversity programs and activities, including programs that improve physics education, increase diversity, provide outreach to the public, and impact public policy. We present the latest programs spearheaded by the Committee on the Status of Women in Physics (CSWP), with highlights from other diversity and education efforts. The CSWP is working to increase the fraction of women in physics, understand and implement solutions for gender-specific issues, enhance professional development opportunities for women in physics, and remedy issues that impact gender inequality in physics. The Conferences for Undergraduate Women in Physics, Professional Skills Development Workshops, and our new Professional Skills program for students and postdocs are all working towards meeting these goals. The CSWP also has site visit and conversation visit programs, where department chairs request that the APS assess the climate for women in their departments or facilitate climate discussions. APS also has two significant programs to increase participation by underrepresented minorities (URM). The newest program, the APS National Mentoring Community, is working to provide mentoring to URM undergraduates, and the APS Bridge Program is an established effort that is dramatically increasing the number of URM PhDs in physics.

  18. An overview of the fire risk scoping study objectives, approach, findings and follow-on efforts

    International Nuclear Information System (INIS)

    Nowlen, S.P.; Lambright, J.A.; Nicolette, V.F.; Bohn, M.P.

    1989-01-01

    The Fire Risk Scoping Study was sponsored by the US Nuclear Regulatory Commission and performed at Sandia National Laboratories. The study was initiated as a result of previous USNRC-sponsored fire research efforts that had identified certain fire risk issues which had not been addressed in previously completed commercial nuclear power plant fire risk analyses. The specific objectives of this study were (1) to review and requantify fire risk scenarios from four fire probabilistic risk assessments (PRAs) in light of updated data bases made available as a result of USNRC sponsored Fire Protection Research Program and updated computer fire modeling capabilities, (2) to identify potentially significant fire risk issues that have not been previously addressed in a fire risk context and to quantify the potential impact of those identified fire risk issues where possible, and (3) to review current fire regulations and plant implementation practices for relevance to the identified unaddressed fire risk issues. 8 refs., 2 tabs

  19. Automatic electromagnetic valve for previous vacuum

    International Nuclear Information System (INIS)

    Granados, C. E.; Martin, F.

    1959-01-01

    A valve which permits the maintenance of an installation vacuum when electric current fails is described. It also lets the air in the previous vacuum bomb to prevent the oil ascending in the vacuum tubes. (Author)

  20. Supporting Students as Scientists: One Mission's Efforts

    Science.gov (United States)

    Taylor, J.; Chambers, L. H.; Trepte, C. R.

    2012-12-01

    NASA's CALIPSO satellite mission provides an array of opportunities for teachers, students, and the general public. In developing our latest plan for education and public outreach, CALIPSO focused on efforts that would support students as scientists. CALIPSO EPO activities are aimed at inspiring young scientists through multiple avenues of potential contact, including: educator professional development, student-scientist mentoring, curriculum resource development, and public outreach through collaborative mission efforts. In this session, we will explore how these avenues complement one another and take a closer look at the development of the educator professional development activities. As part of CALIPSO's EPO efforts, we have developed the GLOBE Atmosphere Investigations Programs (AIP). The program encourages students to engage in authentic science through research on the atmosphere. The National Research Council (NRC) has emphasized the importance of teaching scientific inquiry in the National Science Education Standards (1996, 2000) and scientific practice in the recent Framework for K-12 Science Education (2011). In order to encourage student-centered science inquiry, teacher training utilizing GLOBE Atmosphere Investigations and GLOBE's Student Research Process are provided to middle and high school teachers to assist them in incorporating real scientific investigations into their classroom. Through participation in the program, teachers become a part of GLOBE (Global Learning and Observations to Benefit the Environment) - an international community of teachers, students, and scientists studying environmental science in over 24,000 schools around the world. The program uses NASA's satellites and the collection of atmosphere data by students to provide an engaging science learning experience for the students, and teachers. The GLOBE Atmosphere Investigations program offers year-long support to both teachers and students through direct involvement with NASA

  1. Development Efforts Of Oil Companies As Perceived By Rural ...

    African Journals Online (AJOL)

    ... that the host communities are highly satisfied with companies' efforts (projects and services) to them. Based on these findings, recommendations were made. Key words: Oil producing communities; oil exploration/production; company's development efforts; Journal of Agriculture and Social Research Vol.4(1) 2004: 60-71 ...

  2. Private Speech Moderates the Effects of Effortful Control on Emotionality

    Science.gov (United States)

    Day, Kimberly L.; Smith, Cynthia L.; Neal, Amy; Dunsmore, Julie C.

    2018-01-01

    Research Findings: In addition to being a regulatory strategy, children's private speech may enhance or interfere with their effortful control used to regulate emotion. The goal of the current study was to investigate whether children's private speech during a selective attention task moderated the relations of their effortful control to their…

  3. Termination of prehospital resuscitative efforts

    DEFF Research Database (Denmark)

    Mikkelsen, Søren; Schaffalitzky de Muckadell, Caroline; Binderup, Lars Grassmé

    2017-01-01

    -and-death decision-making in the patient's medical records is required. We suggest that a template be implemented in the prehospital medical records describing the basis for any ethical decisions. This template should contain information regarding the persons involved in the deliberations and notes on ethical......BACKGROUND: Discussions on ethical aspects of life-and-death decisions within the hospital are often made in plenary. The prehospital physician, however, may be faced with ethical dilemmas in life-and-death decisions when time-critical decisions to initiate or refrain from resuscitative efforts...... need to be taken without the possibility to discuss matters with colleagues. Little is known whether these considerations regarding ethical issues in crucial life-and-death decisions are documented prehospitally. This is a review of the ethical considerations documented in the prehospital medical...

  4. Students' Academic Performance: Academic Effort Is an Intervening ...

    African Journals Online (AJOL)

    PROMOTING ACCESS TO AFRICAN RESEARCH ... Students' Academic Performance: Academic Effort Is an Intervening Variable ... This study was designed to seek explanations for differences in academic performance among junior ...

  5. Students Collaborating to Undertake Tracking Efforts for Sturgeon(SCUTES)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Students Collaborating to Undertake Tracking Efforts for Sturgeon (SCUTES) is a collaboration between NOAA Fisheries, sturgeon researchers, and teachers/educators in...

  6. 77 FR 70176 - Previous Participation Certification

    Science.gov (United States)

    2012-11-23

    ... participants' previous participation in government programs and ensure that the past record is acceptable prior... information is designed to be 100 percent automated and digital submission of all data and certifications is... government programs and ensure that the past record is acceptable prior to granting approval to participate...

  7. On the Tengiz petroleum deposit previous study

    International Nuclear Information System (INIS)

    Nysangaliev, A.N.; Kuspangaliev, T.K.

    1997-01-01

    Tengiz petroleum deposit previous study is described. Some consideration about structure of productive formation, specific characteristic properties of petroleum-bearing collectors are presented. Recommendation on their detail study and using of experience on exploration and development of petroleum deposit which have analogy on most important geological and industrial parameters are given. (author)

  8. Subsequent pregnancy outcome after previous foetal death

    NARCIS (Netherlands)

    Nijkamp, J. W.; Korteweg, F. J.; Holm, J. P.; Timmer, A.; Erwich, J. J. H. M.; van Pampus, M. G.

    Objective: A history of foetal death is a risk factor for complications and foetal death in subsequent pregnancies as most previous risk factors remain present and an underlying cause of death may recur. The purpose of this study was to evaluate subsequent pregnancy outcome after foetal death and to

  9. [Limitation of the therapeutic effort].

    Science.gov (United States)

    Herreros, B; Palacios, G; Pacho, E

    2012-03-01

    The limitation of the therapeutic effort (LTE) consists in not applying extraordinary or disproportionate measures for therapeutic purposes that are proposed for a patient with poor life prognosis and/or poor quality of life. There are two types. The first is to not initiate certain measures or to withdraw them when they are established. A decision of the LTE should be based on some rigorous criteria, so that we make the following proposal. First, it is necessary to know the most relevant details of the case to make a decision: the preferences of the patient, the preferences of the family when pertinent, the prognosis (severity), the quality of life and distribution of the limited resources. After, the decision should be made. In this phase, participatory deliberation should be established to clarify the end of the intervention. Finally, if it is decided to perform an LTE, it should be decided how to do it. Special procedures, disproportionate measures, that are useless and vain should not be initiated for the therapeutic objective designed (withdraw them if they have been established). When it has been decided to treat a condition (interim measures), the treatment should be maintained. This complex phase may need stratification of he measures. Finally, the necessary palliative measures should be established. Copyright © 2011 Elsevier España, S.L. All rights reserved.

  10. Mental and physical effort affect vigilance differently

    NARCIS (Netherlands)

    Smit, A.S.; Eling, P.A.T.M.; Hopman, M.T.E.; Coenen, A.M.L.

    2005-01-01

    Both physical and mental effort are thought to affect vigilance. Mental effort is known for its vigilance declining effects, but the effects of physical effort are less clear. This study investigated whether these two forms of effort affect the EEG and subjective alertness differently. Participants

  11. Mental and physical effort affect vigilance differently.

    NARCIS (Netherlands)

    Smit, A.S.; Eling, P.A.T.M.; Hopman, M.T.E.; Coenen, A.M.L.

    2005-01-01

    Both physical and mental effort are thought to affect vigilance. Mental effort is known for its vigilance declining effects, but the effects of physical effort are less clear. This study investigated whether these two forms of effort affect the EEG and subjective alertness differently. Participants

  12. Challenging previous conceptions of vegetarianism and eating disorders.

    Science.gov (United States)

    Fisak, B; Peterson, R D; Tantleff-Dunn, S; Molnar, J M

    2006-12-01

    The purpose of this study was to replicate and expand upon previous research that has examined the potential association between vegetarianism and disordered eating. Limitations of previous research studies are addressed, including possible low reliability of measures of eating pathology within vegetarian samples, use of only a few dietary restraint measures, and a paucity of research examining potential differences in body image and food choice motives of vegetarians versus nonvegetarians. Two hundred and fifty-six college students completed a number of measures of eating pathology and body image, and a food choice motives questionnaire. Interestingly, no significant differences were found between vegetarians and nonvegetarians in measures of eating pathology or body image. However, significant differences in food choice motives were found. Implications for both researchers and clinicians are discussed.

  13. Minimal-effort planning of active alignment processes for beam-shaping optics

    Science.gov (United States)

    Haag, Sebastian; Schranner, Matthias; Müller, Tobias; Zontar, Daniel; Schlette, Christian; Losch, Daniel; Brecher, Christian; Roßmann, Jürgen

    2015-03-01

    In science and industry, the alignment of beam-shaping optics is usually a manual procedure. Many industrial applications utilizing beam-shaping optical systems require more scalable production solutions and therefore effort has been invested in research regarding the automation of optics assembly. In previous works, the authors and other researchers have proven the feasibility of automated alignment of beam-shaping optics such as collimation lenses or homogenization optics. Nevertheless, the planning efforts as well as additional knowledge from the fields of automation and control required for such alignment processes are immense. This paper presents a novel approach of planning active alignment processes of beam-shaping optics with the focus of minimizing the planning efforts for active alignment. The approach utilizes optical simulation and the genetic programming paradigm from computer science for automatically extracting features from a simulated data basis with a high correlation coefficient regarding the individual degrees of freedom of alignment. The strategy is capable of finding active alignment strategies that can be executed by an automated assembly system. The paper presents a tool making the algorithm available to end-users and it discusses the results of planning the active alignment of the well-known assembly of a fast-axis collimator. The paper concludes with an outlook on the transferability to other use cases such as application specific intensity distributions which will benefit from reduced planning efforts.

  14. The job satisfaction of principals of previously disadvantaged schools

    African Journals Online (AJOL)

    The aim of this study was to identify influences on the job satisfaction of previously disadvantaged school principals in North-West Province. Evans's theory of job satisfaction, morale and motivation was useful as a conceptual framework. A mixedmethods explanatory research design was important in discovering issues with ...

  15. Perception of effort in Exercise Science: Definition, measurement and perspectives.

    Science.gov (United States)

    Pageaux, Benjamin

    2016-11-01

    Perception of effort, also known as perceived exertion or sense of effort, can be described as a cognitive feeling of work associated with voluntary actions. The aim of the present review is to provide an overview of what is perception of effort in Exercise Science. Due to the addition of sensations other than effort in its definition, the neurophysiology of perceived exertion remains poorly understood. As humans have the ability to dissociate effort from other sensations related to physical exercise, the need to use a narrower definition is emphasised. Consequently, a definition and some brief guidelines for its measurement are provided. Finally, an overview of the models present in the literature aiming to explain its neurophysiology, and some perspectives for future research are offered.

  16. Sebacinales Everywhere: Previously Overlooked Ubiquitous Fungal Endophytes

    Czech Academy of Sciences Publication Activity Database

    Weiss, M.; Sýkorová, Zuzana; Garnica, S.; Riess, K.; Martos, F.; Krause, C.; Oberwinkler, F.; Bauer, R.; Redecker, D.

    2011-01-01

    Roč. 6, č. 2 (2011), s. 1-7 E-ISSN 1932-6203 Institutional research plan: CEZ:AV0Z60050516 Keywords : Sebacinales * endophytes * mycorrhiza Subject RIV: EF - Botanics Impact factor: 4.092, year: 2011

  17. Self-regulating the effortful "social dos".

    Science.gov (United States)

    Cortes, Kassandra; Kammrath, Lara K; Scholer, Abigail A; Peetz, Johanna

    2014-03-01

    In the current research, we explored differences in the self-regulation of the personal dos (i.e., engaging in active and effortful behaviors that benefit the self) and in the self-regulation of the social dos (engaging in those same effortful behaviors to benefit someone else). In 6 studies, we examined whether the same trait self-control abilities that predict task persistence on personal dos would also predict task persistence on social dos. That is, would the same behavior, such as persisting through a tedious and attentionally demanding task, show different associations with trait self-control when it is framed as benefitting the self versus someone else? In Studies 1-3, we directly compared the personal and social dos and found that trait self-control predicted self-reported and behavioral personal dos but not social dos, even when the behaviors were identical and when the incentives were matched. Instead, trait agreeableness--a trait linked to successful self-regulation within the social domain--predicted the social dos. Trait self-control did not predict the social dos even when task difficulty increased (Study 4), but it did predict the social don'ts, consistent with past research (Studies 5-6). The current studies provide support for the importance of distinguishing different domains of self-regulated behaviors and suggest that social dos can be successfully performed through routes other than traditional self-control abilities. (PsycINFO Database Record (c) 2014 APA, all rights reserved).

  18. Books average previous decade of economic misery.

    Science.gov (United States)

    Bentley, R Alexander; Acerbi, Alberto; Ormerod, Paul; Lampos, Vasileios

    2014-01-01

    For the 20(th) century since the Depression, we find a strong correlation between a 'literary misery index' derived from English language books and a moving average of the previous decade of the annual U.S. economic misery index, which is the sum of inflation and unemployment rates. We find a peak in the goodness of fit at 11 years for the moving average. The fit between the two misery indices holds when using different techniques to measure the literary misery index, and this fit is significantly better than other possible correlations with different emotion indices. To check the robustness of the results, we also analysed books written in German language and obtained very similar correlations with the German economic misery index. The results suggest that millions of books published every year average the authors' shared economic experiences over the past decade.

  19. Books Average Previous Decade of Economic Misery

    Science.gov (United States)

    Bentley, R. Alexander; Acerbi, Alberto; Ormerod, Paul; Lampos, Vasileios

    2014-01-01

    For the 20th century since the Depression, we find a strong correlation between a ‘literary misery index’ derived from English language books and a moving average of the previous decade of the annual U.S. economic misery index, which is the sum of inflation and unemployment rates. We find a peak in the goodness of fit at 11 years for the moving average. The fit between the two misery indices holds when using different techniques to measure the literary misery index, and this fit is significantly better than other possible correlations with different emotion indices. To check the robustness of the results, we also analysed books written in German language and obtained very similar correlations with the German economic misery index. The results suggest that millions of books published every year average the authors' shared economic experiences over the past decade. PMID:24416159

  20. New generation of space capabilities resulting from US/RF cooperative efforts

    Science.gov (United States)

    Humpherys, Thomas; Misnik, Victor; Sinelshchikov, Valery; Stair, A. T., Jr.; Khatulev, Valery; Carpenter, Jack; Watson, John; Chvanov, Dmitry; Privalsky, Victor

    2006-09-01

    Previous successful international cooperative efforts offer a wealth of experience in dealing with highly sensitive issues, but cooperative remote sensing for monitoring and understanding the global environmental is in the national interest of all countries. Cooperation between international partners is paramount, particularly with the Russian Federation, due to its technological maturity and strategic political and geographical position in the world. Based on experience gained over a decade of collaborative space research efforts, continued cooperation provides an achievable goal as well as understanding the fabric of our coexistence. Past cooperative space research efforts demonstrate the ability of the US and Russian Federation to develop a framework for cooperation, working together on a complex, state-of-the-art joint satellite program. These efforts consisted of teams of scientists and engineers who overcame numerous cultural, linguistic, engineering approaches and different political environments. Among these major achievements are: (1) field measurement activities with US satellites MSTI and MSX and the Russian RESURS-1 satellite, as well as the joint experimental use of the US FISTA aircraft; (2) successful joint Science, Conceptual and Preliminary Design Reviews; (3) joint publications of scientific research technical papers, (4) Russian investment in development, demonstration and operation of the Monitor-E spacecraft (Yacht satellite bus), (5) successful demonstration of the conversion of the SS-19 into a satellite launch system, and (6) negotiation of contractual and technical assistant agreements. This paper discusses a new generation of science and space capabilities available to the Remote Sensing community. Specific topics include: joint requirements definition process and work allocation for hardware and responsibility for software development; the function, description and status of Russian contributions in providing space component prototypes

  1. Optimal Effort in Consumer Choice : Theory and Experimental Evidence for Binary Choice

    NARCIS (Netherlands)

    Conlon, B.J.; Dellaert, B.G.C.; van Soest, A.H.O.

    2001-01-01

    This paper develops a theoretical model of optimal effort in consumer choice.The model extends previous consumer choice models in that the consumer not only chooses a product, but also decides how much effort to apply to a given choice problem.The model yields a unique optimal level of effort, which

  2. Measuring collections effort improves cash performance.

    Science.gov (United States)

    Shutts, Joe

    2009-09-01

    Having a satisfied work force can lead to an improved collections effort. Hiring the right people and training them ensures employee engagement. Measuring collections effort and offering incentives is key to revenue cycle success.

  3. Spent fuel and high level waste: Chemical durability and performance under simulated repository conditions. Results of a coordinated research project 1998-2004. Part 2: Results of a previously unpublished CRP: Performance of high level waste forms and packages under repository conditions. Results of a co-ordinated research project 1991-1998

    International Nuclear Information System (INIS)

    2007-07-01

    The objective of the CRP (Coordinated Research Projekt) on the 'Performance of High Level Waste Forms and Packages under Repository Conditions' was to contribute to the development and implementation of proper and sound technologies for HLW and spent fuel management. Special emphasis was given to the identification of various waste form properties and the study of their long term durability in simulated repository conditions. Another objective was to promote the co-operation and exchange of information between Member States on experimental concerning behaviour of the waste form. The CRP was composed of research contracts and agreements with Argentina, Australia, Belgium, Canada, China, Czech Republic, Finland, France, Germany, India, Japan, Russia, and the United States of America. The publication includes 14 individual contributions of the participants to the CRP, which are indexed separately.

  4. Research

    African Journals Online (AJOL)

    ebutamanya

    2015-05-25

    May 25, 2015 ... Abstract. Introduction: insecticide-treated nets (ITNs) stood at center in the current efforts to prevent and control malaria at community and individual levels. Though ITNs are the most prominent measure for large-scale deployment in highly endemic areas their compliance in terms of ownership and usage ...

  5. Dopamine does double duty in motivating cognitive effort

    Science.gov (United States)

    Westbrook, Andrew; Braver, Todd S.

    2015-01-01

    Cognitive control is subjectively costly, suggesting that engagement is modulated in relationship to incentive state. Dopamine appears to play key roles. In particular, dopamine may mediate cognitive effort by two broad classes of functions: 1) modulating the functional parameters of working memory circuits subserving effortful cognition, and 2) mediating value-learning and decision-making about effortful cognitive action. Here we tie together these two lines of research, proposing how dopamine serves “double duty”, translating incentive information into cognitive motivation. PMID:26889810

  6. Goddard Technology Efforts to Improve Space Borne Laser Reliability

    Science.gov (United States)

    Heaps, William S.

    2006-01-01

    In an effort to reduce the risk, perceived and actual, of employing instruments containing space borne lasers NASA initiated the Laser Risk Reduction Program (LRRP) in 2001. This program managed jointly by NASA Langley and NASA Goddard and employing lasers researchers from government, university and industrial labs is nearing the conclusion of its planned 5 year duration. This paper will describe some of the efforts and results obtained by the Goddard half of the program.

  7. Underestimation of Severity of Previous Whiplash Injuries

    Science.gov (United States)

    Naqui, SZH; Lovell, SJ; Lovell, ME

    2008-01-01

    INTRODUCTION We noted a report that more significant symptoms may be expressed after second whiplash injuries by a suggested cumulative effect, including degeneration. We wondered if patients were underestimating the severity of their earlier injury. PATIENTS AND METHODS We studied recent medicolegal reports, to assess subjects with a second whiplash injury. They had been asked whether their earlier injury was worse, the same or lesser in severity. RESULTS From the study cohort, 101 patients (87%) felt that they had fully recovered from their first injury and 15 (13%) had not. Seventy-six subjects considered their first injury of lesser severity, 24 worse and 16 the same. Of the 24 that felt the violence of their first accident was worse, only 8 had worse symptoms, and 16 felt their symptoms were mainly the same or less than their symptoms from their second injury. Statistical analysis of the data revealed that the proportion of those claiming a difference who said the previous injury was lesser was 76% (95% CI 66–84%). The observed proportion with a lesser injury was considerably higher than the 50% anticipated. CONCLUSIONS We feel that subjects may underestimate the severity of an earlier injury and associated symptoms. Reasons for this may include secondary gain rather than any proposed cumulative effect. PMID:18201501

  8. [Electronic cigarettes - effects on health. Previous reports].

    Science.gov (United States)

    Napierała, Marta; Kulza, Maksymilian; Wachowiak, Anna; Jabłecka, Katarzyna; Florek, Ewa

    2014-01-01

    Currently very popular in the market of tobacco products have gained electronic cigarettes (ang. E-cigarettes). These products are considered to be potentially less harmful in compared to traditional tobacco products. However, current reports indicate that the statements of the producers regarding to the composition of the e- liquids not always are sufficient, and consumers often do not have reliable information on the quality of the product used by them. This paper contain a review of previous reports on the composition of e-cigarettes and their impact on health. Most of the observed health effects was related to symptoms of the respiratory tract, mouth, throat, neurological complications and sensory organs. Particularly hazardous effects of the e-cigarettes were: pneumonia, congestive heart failure, confusion, convulsions, hypotension, aspiration pneumonia, face second-degree burns, blindness, chest pain and rapid heartbeat. In the literature there is no information relating to passive exposure by the aerosols released during e-cigarette smoking. Furthermore, the information regarding to the use of these products in the long term are not also available.

  9. Dissociating variability and effort as determinants of coordination.

    Directory of Open Access Journals (Sweden)

    Ian O'Sullivan

    2009-04-01

    Full Text Available When coordinating movements, the nervous system often has to decide how to distribute work across a number of redundant effectors. Here, we show that humans solve this problem by trying to minimize both the variability of motor output and the effort involved. In previous studies that investigated the temporal shape of movements, these two selective pressures, despite having very different theoretical implications, could not be distinguished; because noise in the motor system increases with the motor commands, minimization of effort or variability leads to very similar predictions. When multiple effectors with different noise and effort characteristics have to be combined, however, these two cost terms can be dissociated. Here, we measure the importance of variability and effort in coordination by studying how humans share force production between two fingers. To capture variability, we identified the coefficient of variation of the index and little fingers. For effort, we used the sum of squared forces and the sum of squared forces normalized by the maximum strength of each effector. These terms were then used to predict the optimal force distribution for a task in which participants had to produce a target total force of 4-16 N, by pressing onto two isometric transducers using different combinations of fingers. By comparing the predicted distribution across fingers to the actual distribution chosen by participants, we were able to estimate the relative importance of variability and effort of 1:7, with the unnormalized effort being most important. Our results indicate that the nervous system uses multi-effector redundancy to minimize both the variability of the produced output and effort, although effort costs clearly outweighed variability costs.

  10. Implicit activation of the aging stereotype influences effort-related cardiovascular response: The role of incentive.

    Science.gov (United States)

    Zafeiriou, Athina; Gendolla, Guido H E

    2017-09-01

    Based on previous research on implicit effects on effort-related cardiovascular response and evidence that aging is associated with cognitive difficulties, we tested whether the mere activation of the aging stereotype can systematically influence young individuals' effort-mobilization during cognitive performance. Young participants performed an objectively difficult short-term memory task during which they processed elderly vs. youth primes and expected low vs. high incentive for success. When participants processed elderly primes during the task, we expected cardiovascular response to be weak in the low-incentive condition and strong in the high-incentive condition. Unaffected by incentive, effort in the youth-prime condition should fall in between the two elderly-prime cells. Effects on cardiac pre-ejection period (PEP) and heart rate (HR) largely supported these predictions. The present findings show for the first time that the mere activation of the aging stereotype can systematically influence effort mobilization during cognitive performance-even in young adults. Copyright © 2017 Elsevier B.V. All rights reserved.

  11. Research

    African Journals Online (AJOL)

    ebutamanya

    2015-03-02

    Mar 2, 2015 ... Joseph Daniels1,&, Ruth Nduati1,2, James Kiarie1,3, Carey Farquhar1,4,5 .... or basic science research career (Socio-Behavioral Research, .... a research environment that supports knowledge sharing to develop research ...

  12. Research

    African Journals Online (AJOL)

    abp

    2017-10-24

    Oct 24, 2017 ... Health Insurance Programme (TISHIP) in Nigeria: a case study of ... University Medical Centre staff responses showed a satisfactory scheme implementation. ... benefits. Previous studies revealed that students barely visit.

  13. Research

    African Journals Online (AJOL)

    abp

    2013-07-23

    Jul 23, 2013 ... 1Department of Family Medicine, Faculty of Medicine, Suez Canal University, Egypt. &Corresponding ... Results: Hundred family physicians were included in the study. They were previously ..... organization. There was a ...

  14. Research

    African Journals Online (AJOL)

    raoul

    2012-04-16

    Apr 16, 2012 ... We chose to include male students in our study because previous studies have shown widespread lack of knowledge of the disease .... masculinity. ... The last few years have seen widespread use of internet social media.

  15. Previous climatic alterations are caused by the sun

    International Nuclear Information System (INIS)

    Groenaas, Sigbjoern

    2003-01-01

    The article surveys the scientific results of previous research into the contribution of the sun to climatic alterations. The author concludes that there is evidence of eight cold periods after the last ice age and that the alterations largely were due to climate effects from the sun. However, these effects are only causing a fraction of the registered global warming. It is assumed that the human activities are contributing to the rest of the greenhouse effect

  16. The effects of freedom of choice in action selection on perceived mental effort and the sense of agency.

    Science.gov (United States)

    Barlas, Zeynep; Hockley, William E; Obhi, Sukhvinder S

    2017-10-01

    Previous research showed that increasing the number of action alternatives enhances the sense of agency (SoA). Here, we investigated whether choice space could affect subjective judgments of mental effort experienced during action selection and examined the link between subjective effort and the SoA. Participants performed freely selected (among two, three, or four options) and instructed actions that produced pleasant or unpleasant tones. We obtained action-effect interval estimates to quantify intentional binding - the perceived interval compression between actions and outcomes and feeling of control (FoC) ratings. Additionally, participants reported the degree of mental effort they experienced during action selection. We found that both binding and FoC were systematically enhanced with increasing choice-level. Outcome valence did not influence binding, while FoC was stronger for pleasant than unpleasant outcomes. Finally, freely chosen actions were associated with low subjective effort and slow responses (i.e., higher reaction times), and instructed actions were associated with high effort and fast responses. Although the conditions that yielded the greatest and least subjective effort also yielded the greatest and least binding and FoC, there was no significant correlation between subjective effort and SoA measures. Overall, our results raise interesting questions about how agency may be influenced by response selection demands (i.e., indexed by speed of responding) and subjective mental effort. Our work also highlights the importance of understanding how subjective mental effort and response speed are related to popular notions of fluency in response selection. Copyright © 2017 Elsevier B.V. All rights reserved.

  17. New research centre supports adaptation efforts in Egypt's Nile Delta

    International Development Research Centre (IDRC) Digital Library (Canada)

    2014-06-20

    Jun 20, 2014 ... ... one of the world's most vulnerable regions to climate change threats. ... This effect was recently explored in another IDRC-supported project, which ... in Kenya, farmers seldom use them for farm level decision-making.

  18. NREL at 40: Research Efforts Drive Advanced Energy | News | NREL

    Science.gov (United States)

    benefits. The laboratory gives U.S. entrepreneurs a competitive edge in the global energy race by bridging a steadily increasing amount of solar power added annually and a single gigawatt (GW) having the increasing obstacles in transporting these massive structures." The solution may be in manufacturing

  19. Previous Experience a Model of Practice UNAE

    Directory of Open Access Journals (Sweden)

    Ormary Barberi Ruiz

    2017-02-01

    Full Text Available The statements presented in this article represents a preliminary version of the proposed model of pre-professional practices (PPP of the National University of Education (UNAE of Ecuador, an urgent institutional necessity is revealed in the descriptive analyzes conducted from technical support - administrative (reports, interviews, testimonials, pedagogical foundations of UNAE (curricular directionality, transverse axes in practice, career plan, approach and diagnostic examination as subject nature of the pre professional practice and the demand of socio educational contexts where the practices have been emerging to resize them. By relating these elements allowed conceiving the modeling of the processes of the pre-professional practices for the development of professional skills of future teachers through four components: contextual projective, implementation (tutoring, accompaniment (teaching couple and monitoring (meetings at the beginning, during and end of practice. The initial training of teachers is inherent to teaching (academic and professional training, research and links with the community, these are fundamental pillars of Ecuadorian higher education.

  20. Local recurrence risk after previous salvage mastectomy.

    Science.gov (United States)

    Tanabe, M; Iwase, T; Okumura, Y; Yoshida, A; Masuda, N; Nakatsukasa, K; Shien, T; Tanaka, S; Komoike, Y; Taguchi, T; Arima, N; Nishimura, R; Inaji, H; Ishitobi, M

    2016-07-01

    Breast-conserving surgery is a standard treatment for early breast cancer. For ipsilateral breast tumor recurrence (IBTR) after breast-conserving surgery, salvage mastectomy is the current standard surgical procedure. However, it is not rare for patients with IBTR who have received salvage mastectomy to develop local recurrence. In this study, we examined the risk factors of local recurrence after salvage mastectomy for IBTR. A total of 118 consecutive patients who had histologically confirmed IBTR without distant metastases and underwent salvage mastectomy without irradiation for IBTR between 1989 and 2008 were included from eight institutions in Japan. The risk factors of local recurrence were assessed. The median follow-up period from salvage mastectomy for IBTR was 4.6 years. Patients with pN2 or higher on diagnosis of the primary tumor showed significantly poorer local recurrence-free survival than those with pN0 or pN1 at primary tumor (p mastectomy for IBTR. Further research and validation studies are needed. (UMIN-CTR number UMIN000008136). Copyright © 2016 Elsevier Ltd. All rights reserved.

  1. NREL Quickens its Tech Transfer Efforts

    Energy Technology Data Exchange (ETDEWEB)

    Lammers, H.

    2012-02-01

    Innovations and 'aha' movements in renewable energy and energy efficiency, while exciting in the lab, only truly live up to their promise once they find a place in homes or business. Late last year President Obama issued a directive to all federal agencies to increase their efforts to transfer technologies to the private sector in order to achieve greater societal and economic impacts of federal research investments. The president's call to action includes efforts to establish technology transfer goals and to measure progress, to engage in efforts to increase the speed of technology transfer and to enhance local and regional innovation partnerships. But, even before the White House began its initiative to restructure the commercialization process, the National Renewable Energy Laboratory had a major effort underway designed to increase the speed and impact of technology transfer activities and had already made sure its innovations had a streamlined path to the private sector. For the last three years, NREL has been actively setting commercialization goals and tracking progress against those goals. For example, NREL sought to triple the number of innovations over a five-year period that began in 2009. Through best practices associated with inventor engagement, education and collaboration, NREL quadrupled the number of innovations in just three years. Similar progress has been made in patenting, licensing transactions, income generation and rewards to inventors. 'NREL is known nationally for our cutting-edge research and companies know to call us when they are ready to collaborate,' William Farris, vice president for commercialization and technology transfer, said. 'Once a team is ready to dive in, they don't want be mired in paperwork. We've worked to make our process for licensing NREL technology faster; it now takes less than 60 days for us to come to an agreement and start work with a company interested in our research

  2. Research

    African Journals Online (AJOL)

    A descriptive qualitative research design was used to determine whether participants ... simulation as a teaching method; a manikin offering effective learning; confidence ..... Tesch R. Qualitative Research: Analysis Types and Software Tools.

  3. Investigating the Nature of Relationship between Software Size and Development Effort

    OpenAIRE

    Bajwa, Sohaib-Shahid

    2008-01-01

    Software effort estimation still remains a challenging and debatable research area. Most of the software effort estimation models take software size as the base input. Among the others, Constructive Cost Model (COCOMO II) is a widely known effort estimation model. It uses Source Lines of Code (SLOC) as the software size to estimate effort. However, many problems arise while using SLOC as a size measure due to its late availability in the software life cycle. Therefore, a lot of research has b...

  4. Cognitive dissonance in children: justification of effort or contrast?

    Science.gov (United States)

    Alessandri, Jérôme; Darcheville, Jean-Claude; Zentall, Thomas R

    2008-06-01

    Justification of effort is a form of cognitive dissonance in which the subjective value of an outcome is directly related to the effort that went into obtaining it. However, it is likely that in social contexts (such as the requirements for joining a group) an inference can be made (perhaps incorrectly) that an outcome that requires greater effort to obtain in fact has greater value. Here we present evidence that a cognitive dissonance effect can be found in children under conditions that offer better control for the social value of the outcome. This effect is quite similar to contrast effects that recently have been studied in animals. We suggest that contrast between the effort required to obtain the outcome and the outcome itself provides a more parsimonious account of this phenomenon and perhaps other related cognitive dissonance phenomena as well. Research will be needed to identify cognitive dissonance processes that are different from contrast effects of this kind.

  5. Pocket money and child effort at school

    OpenAIRE

    François-Charles Wolff; Christine Barnet-Verzat

    2008-01-01

    In this paper, we study the relationship between the provision of parental pocket and the level of effort undertaken by the child at school. Under altruism, an increased amount of parental transfer should reduce the child's effort. Our empirical analysis is based on a French data set including about 1,400 parent-child pairs. We find that children do not undertake less effort when their parents are more generous.

  6. Research

    African Journals Online (AJOL)

    research process, as part of which students must find and appraise evidence from research.[5] This highlights that teaching research methodology is inclined towards equipping students ... Students believed that evidence-based practice was vital, yet their understanding of the concept was restricted when compared with the.

  7. Incentive Design and Mis-Allocated Effort

    OpenAIRE

    Schnedler, Wendelin

    2013-01-01

    Incentives often distort behavior: they induce agents to exert effort but this effort is not employed optimally. This paper proposes a theory of incentive design allowing for such distorted behavior. At the heart of the theory is a trade-off between getting the agent to exert effort and ensuring that this effort is used well. The theory covers various moral-hazard models, ranging from traditional single-task to multi-task models. It also provides -for the first time- a formalization and proof...

  8. Global Data Grid Efforts for ATLAS

    CERN Multimedia

    Gardner, R.

    2001-01-01

    Over the past two years computational data grids have emerged as a promising new technology for large scale, data-intensive computing required by the LHC experiments, as outlined by the recent "Hoffman" review panel that addressed the LHC computing challenge. The problem essentially is to seamlessly link physicists to petabyte-scale data and computing resources, distributed worldwide, and connected by high-bandwidth research networks. Several new collaborative initiatives in Europe, the United States, and Asia have formed to address the problem. These projects are of great interest to ATLAS physicists and software developers since their objective is to offer tools that can be integrated into the core ATLAS application framework for distributed event reconstruction, Monte Carlo simulation, and data analysis, making it possible for individuals and groups of physicists to share information, data, and computing resources in new ways and at scales not previously attempted. In addition, much of the distributed IT...

  9. Research

    African Journals Online (AJOL)

    abp

    2016-07-20

    Jul 20, 2016 ... Abstract. Introduction: In sub Saharan Africa, childbirth remains a challenge that creates the need for additional screening tools. Maternal pelvis height, which is currently in use by automotive engineers has previously been shown to have significant associations with various childbirth related outcomes and ...

  10. Research

    African Journals Online (AJOL)

    retention in a newly established medical school in Tanzania. Previous studies found that small salaries, limited career options, heavy teaching loads, growing enrolment and the absence of equipment and support staff were the main barriers to retain faculty staff.[11] These factors have been confirmed by the study at CUHAS ...

  11. Research

    African Journals Online (AJOL)

    [2,3] The definition of a rural-origin student. (ROS) has come under some debate, but for the purpose of this study ... The language of teaching and learning for students not studying in their mother tongue has been seen to pose problems ... trend towards e-learning. Students not previously exposed to this level of technology ...

  12. Time preferences, study effort, and academic performance

    NARCIS (Netherlands)

    Non, J.A.; Tempelaar, D.T.

    2014-01-01

    We analyze the relation between time preferences, study effort, and academic performance among first-year Business and Economics students. Time preferences are measured by stated preferences for an immediate payment over larger delayed payments. Data on study efforts are derived from an electronic

  13. Interests, Effort, Achievement and Vocational Preference.

    Science.gov (United States)

    Sjoberg, L.

    1984-01-01

    Relationships between interest in natural sciences and technology and perceived ability, success, and invested effort were studied in Swedish secondary school students. Interests were accounted for by logical orientation and practical value. Interests and grades were strongly correlated, but correlations between interests and effort and vocational…

  14. Dopamine and Effort-Based Decision Making

    Directory of Open Access Journals (Sweden)

    Irma Triasih Kurniawan

    2011-06-01

    Full Text Available Motivational theories of choice focus on the influence of goal values and strength of reinforcement to explain behavior. By contrast relatively little is known concerning how the cost of an action, such as effort expended, contributes to a decision to act. Effort-based decision making addresses how we make an action choice based on an integration of action and goal values. Here we review behavioral and neurobiological data regarding the representation of effort as action cost, and how this impacts on decision making. Although organisms expend effort to obtain a desired reward there is a striking sensitivity to the amount of effort required, such that the net preference for an action decreases as effort cost increases. We discuss the contribution of the neurotransmitter dopamine (DA towards overcoming response costs and in enhancing an animal’s motivation towards effortful actions. We also consider the contribution of brain structures, including the basal ganglia (BG and anterior cingulate cortex (ACC, in the internal generation of action involving a translation of reward expectation into effortful action.

  15. Listening Effort With Cochlear Implant Simulations

    NARCIS (Netherlands)

    Pals, Carina; Sarampalis, Anastasios; Başkent, Deniz

    2013-01-01

    Purpose: Fitting a cochlear implant (CI) for optimal speech perception does not necessarily optimize listening effort. This study aimed to show that listening effort may change between CI processing conditions for which speech intelligibility remains constant. Method: Nineteen normal-hearing

  16. Effort and Selection Effects of Incentive Contracts

    NARCIS (Netherlands)

    Bouwens, J.F.M.G.; van Lent, L.A.G.M.

    2003-01-01

    We show that the improved effort of employees associated with incentive contracts depends on the properties of the performance measures used in the contract.We also find that the power of incentives in the contract is only indirectly related to any improved employee effort.High powered incentive

  17. The Effect of Age on Listening Effort

    Science.gov (United States)

    Degeest, Sofie; Keppler, Hannah; Corthals, Paul

    2015-01-01

    Purpose: The objective of this study was to investigate the effect of age on listening effort. Method: A dual-task paradigm was used to evaluate listening effort in different conditions of background noise. Sixty adults ranging in age from 20 to 77 years were included. A primary speech-recognition task and a secondary memory task were performed…

  18. Low-effort thought promotes political conservatism.

    Science.gov (United States)

    Eidelman, Scott; Crandall, Christian S; Goodman, Jeffrey A; Blanchar, John C

    2012-06-01

    The authors test the hypothesis that low-effort thought promotes political conservatism. In Study 1, alcohol intoxication was measured among bar patrons; as blood alcohol level increased, so did political conservatism (controlling for sex, education, and political identification). In Study 2, participants under cognitive load reported more conservative attitudes than their no-load counterparts. In Study 3, time pressure increased participants' endorsement of conservative terms. In Study 4, participants considering political terms in a cursory manner endorsed conservative terms more than those asked to cogitate; an indicator of effortful thought (recognition memory) partially mediated the relationship between processing effort and conservatism. Together these data suggest that political conservatism may be a process consequence of low-effort thought; when effortful, deliberate thought is disengaged, endorsement of conservative ideology increases.

  19. Research

    African Journals Online (AJOL)

    2014-05-06

    May 6, 2014 ... facilitate and support articulation between the ECT mid-level worker qualification and the professional B EMC degree. Methods. The researchers used an exploratory, sequential mixed-method design, which is characterised by a qualitative phase of research followed by a quantitative phase. This design is ...

  20. Research

    African Journals Online (AJOL)

    supports medical education and research at institutions in 12 ... (CBE). CapacityPlus, led by IntraHealth International, is the USAID-funded ... acquire public health, clinical, and/or research skills, usually through applied learning in a .... If students were evaluated, indicate the type of student (i.e. medical, dental, nursing, etc.) ...

  1. Research

    African Journals Online (AJOL)

    abp

    2017-01-24

    Jan 24, 2017 ... and the specific rotavirus VP4 (P-types) and VP7 (G-types) determined. Results: The .... Centre for Virus Research (CVR) of the Kenya Medical Research. Institute (KEMRI) ... rotavirus dsRNA was run on 10% polyacrylamide resolving gels using a large format .... What is known about this topic. •. Rotavirus is ...

  2. Shopping Effort Classification: Implications for Segmenting the College Student Market

    Science.gov (United States)

    Wright, Robert E.; Palmer, John C.; Eidson, Vicky; Griswold, Melissa

    2011-01-01

    Market segmentation strategies based on levels of consumer shopping effort have long been utilized by marketing professionals. Such strategies can be beneficial in assisting marketers with development of appropriate marketing mix variables for segments. However, these types of strategies have not been assessed by researchers examining segmentation…

  3. 48 CFR 1352.231-71 - Duplication of effort.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Duplication of effort. 1352.231-71 Section 1352.231-71 Federal Acquisition Regulations System DEPARTMENT OF COMMERCE CLAUSES... benefit of the Government, and not incidental to any other work, pursuit, research, or purpose of the...

  4. Efforts to Develop a 300°C Solder

    Energy Technology Data Exchange (ETDEWEB)

    Norann, Randy A [Perma Works LLC

    2015-01-25

    This paper covers the efforts made to find a 300°C electrical solder solution for geothermal well monitoring and logging tools by Perma Works LLC. This paper covers: why a high temperature solder is needed, what makes for a good solder, testing flux, testing conductive epoxy and testing intermetallic bonds. Future areas of research are suggested.

  5. Control and Effort Costs Influence the Motivational Consequences of Choice

    Directory of Open Access Journals (Sweden)

    Holly Sullivan-Toole

    2017-05-01

    Full Text Available The act of making a choice, apart from any outcomes the choice may yield, has, paradoxically, been linked to both the enhancement and the detriment of intrinsic motivation. Research has implicated two factors in potentially mediating these contradictory effects: the personal control conferred by a choice and the costs associated with a choice. Across four experiments, utilizing a physical effort task disguised as a simple video game, we systematically varied costs across two levels of physical effort requirements (Low-Requirement, High-Requirement and control over effort costs across three levels of choice (Free-Choice, Restricted-Choice, and No-Choice to disambiguate how these factors affect the motivational consequences of choosing within an effortful task. Together, our results indicated that, in the face of effort requirements, illusory control alone may not sufficiently enhance perceptions of personal control to boost intrinsic motivation; rather, the experience of actual control may be necessary to overcome effort costs and elevate performance. Additionally, we demonstrated that conditions of illusory control, while otherwise unmotivating, can through association with the experience of free-choice, be transformed to have a positive effect on motivation.

  6. The influence of music on mental effort and driving performance.

    Science.gov (United States)

    Ünal, Ayça Berfu; Steg, Linda; Epstude, Kai

    2012-09-01

    The current research examined the influence of loud music on driving performance, and whether mental effort mediated this effect. Participants (N=69) drove in a driving simulator either with or without listening to music. In order to test whether music would have similar effects on driving performance in different situations, we manipulated the simulated traffic environment such that the driving context consisted of both complex and monotonous driving situations. In addition, we systematically kept track of drivers' mental load by making the participants verbally report their mental effort at certain moments while driving. We found that listening to music increased mental effort while driving, irrespective of the driving situation being complex or monotonous, providing support to the general assumption that music can be a distracting auditory stimulus while driving. However, drivers who listened to music performed as well as the drivers who did not listen to music, indicating that music did not impair their driving performance. Importantly, the increases in mental effort while listening to music pointed out that drivers try to regulate their mental effort as a cognitive compensatory strategy to deal with task demands. Interestingly, we observed significant improvements in driving performance in two of the driving situations. It seems like mental effort might mediate the effect of music on driving performance in situations requiring sustained attention. Other process variables, such as arousal and boredom, should also be incorporated to study designs in order to reveal more on the nature of how music affects driving. Copyright © 2012 Elsevier Ltd. All rights reserved.

  7. Cognitive strategies, perception of effort and heart rate in endurance ...

    African Journals Online (AJOL)

    Subjects consisted of eight elite, eight average and eight recreational cyclists. ... was used to document the subjects' verbalised thoughts while training. ... which had not previously been required in similar research on marathon runners.

  8. Visual cues and listening effort: individual variability.

    Science.gov (United States)

    Picou, Erin M; Ricketts, Todd A; Hornsby, Benjamin W Y

    2011-10-01

    To investigate the effect of visual cues on listening effort as well as whether predictive variables such as working memory capacity (WMC) and lipreading ability affect the magnitude of listening effort. Twenty participants with normal hearing were tested using a paired-associates recall task in 2 conditions (quiet and noise) and 2 presentation modalities (audio only [AO] and auditory-visual [AV]). Signal-to-noise ratios were adjusted to provide matched speech recognition across audio-only and AV noise conditions. Also measured were subjective perceptions of listening effort and 2 predictive variables: (a) lipreading ability and (b) WMC. Objective and subjective results indicated that listening effort increased in the presence of noise, but on average the addition of visual cues did not significantly affect the magnitude of listening effort. Although there was substantial individual variability, on average participants who were better lipreaders or had larger WMCs demonstrated reduced listening effort in noise in AV conditions. Overall, the results support the hypothesis that integrating auditory and visual cues requires cognitive resources in some participants. The data indicate that low lipreading ability or low WMC is associated with relatively effortful integration of auditory and visual information in noise.

  9. Programming effort analysis of the ELLPACK language

    Science.gov (United States)

    Rice, J. R.

    1978-01-01

    ELLPACK is a problem statement language and system for elliptic partial differential equations which is implemented by a FORTRAN preprocessor. ELLPACK's principal purpose is as a tool for the performance evaluation of software. However, it is used here as an example with which to study the programming effort required for problem solving. It is obvious that problem statement languages can reduce programming effort tremendously; the goal is to quantify this somewhat. This is done by analyzing the lengths and effort (as measured by Halstead's software science technique) of various approaches to solving these problems.

  10. Research

    African Journals Online (AJOL)

    abp

    2017-10-25

    Oct 25, 2017 ... stigma and superstition are known to lead to frequent presentation .... The limited documented research on challenges to help-seeking behaviour for cancer ..... to touch your breast [16] that breast self-examination may cause.

  11. Research

    African Journals Online (AJOL)

    ebutamanya

    2015-10-02

    Oct 2, 2015 ... thought to prevent infection, but recent research has proven otherwise. In addition ... One patient had ophthalmalgia and was exposed to. Kaiy for one year and ... migraine, ear infections, tuberculosis, bone fractures, epilepsy,.

  12. Research

    African Journals Online (AJOL)

    abp

    2016-07-12

    Jul 12, 2016 ... multiple risk factors provides support for multiple-behavior interventions as ... consumption) with smoking therefore needs further research. As such this study .... restaurants, in bars, and on a statewide basis. They preferred to.

  13. Research

    African Journals Online (AJOL)

    The mini-clinical-evaluation exercise (mini-CEX) is a way of assessing the clinical ... Ethical approval for this study was obtained from the Medical Health. Research ..... mini-CEX assessment and feedback session, the greater the likelihood of.

  14. Research

    African Journals Online (AJOL)

    abp

    2016-04-14

    Apr 14, 2016 ... Qualitative data, content analysis approach was used. Results: Overall 422 .... Study design: A mixed method cross-sectional design using both quantitative and qualitative research methods as described by. Hanson et al [33] ...

  15. Research

    International Nuclear Information System (INIS)

    1999-01-01

    Subjects covered in this section are: (1) PCAST panel promotes energy research cooperation; (2) Letter issued by ANS urges funding balance in FFTF restart consideration and (3) FESAC panel releases report on priorities and balance

  16. Research

    African Journals Online (AJOL)

    Research. December 2017, Vol. 9, No. 4 AJHPE 171. During curriculum development, teachers ... Ideally, examiners need an educational method to determine ..... A major focus of this study was addressing the human resource gap when.

  17. Work ability, effort-reward imbalance and disability pension claims.

    Science.gov (United States)

    Wienert, J; Spanier, K; Radoschewski, F M; Bethge, M

    2017-12-30

    Effort-reward imbalance (ERI) and self-rated work ability are known independent correlates and predictors of intended disability pension claims. However, little research has focused on the interrelationship between the three and whether self-rated work ability mediates the relationship between ERI and intended disability pension claims. To investigate whether self-rated work ability mediates the association between ERI and intended disability pension claims. Baseline data from participants of the Third German Sociomedical Panel of Employees, a 5-year cohort study that investigates determinants of work ability, rehabilitation utilization and disability pensions in employees who have previously received sickness benefits, were analysed. We tested direct associations between ERI with intended disability pension claims (Model 1) and self-rated work ability (Model 2). Additionally, we tested whether work ability mediates the association between ERI and intended disability pension claims (Model 3). There were 2585 participants. Model 1 indicated a significant association between ERI and intended disability pension claims. Model 2 showed a significant association between ERI and self-rated work ability. The mediation in Model 3 revealed a significant indirect association between ERI and intended disability pension claims via self-rated work ability. There was no significant direct association between ERI and intended disability pension claims. Our results support the adverse health-related impact of ERI on self-rated work ability and intended disability pension claims. © The Author 2017. Published by Oxford University Press on behalf of the Society of Occupational Medicine. All rights reserved. For Permissions, please email: journals.permissions@oup.com

  18. Illinois highway materials sustainability efforts of 2015.

    Science.gov (United States)

    2016-08-01

    This report provides a summary of the sustainability efforts of the Illinois Department of Transportation (IDOT) in recycling : reclaimed materials in highway construction during calendar year 2015. This report meets the requirements of Illinois Publ...

  19. EU grid computing effort takes on malaria

    CERN Multimedia

    Lawrence, Stacy

    2006-01-01

    Malaria is the world's most common parasitic infection, affecting more thatn 500 million people annually and killing more than 1 million. In order to help combat malaria, CERN has launched a grid computing effort (1 page)

  20. Illinois highway materials sustainability efforts of 2014.

    Science.gov (United States)

    2015-08-01

    This report presents the 2014 sustainability efforts of the Illinois Department of Transportation (IDOT) in : recycling reclaimed materials in highway construction. This report meets the requirements of Illinois : Public Act 097-0314 by documenting I...

  1. Illinois highway materials sustainability efforts of 2016.

    Science.gov (United States)

    2017-07-04

    This report provides a summary of the sustainability efforts of the Illinois Department of Transportation (IDOT) in recycling : reclaimed materials in highway construction during calendar year 2016. This report meets the requirements of Illinois Publ...

  2. Illinois highway materials sustainability efforts of 2013.

    Science.gov (United States)

    2014-08-01

    This report presents the sustainability efforts of the Illinois Department of Transportation (IDOT) in : recycling and reclaiming materials for use in highway construction. This report meets the requirements of : Illinois Public Act 097-0314 by docum...

  3. Research

    African Journals Online (AJOL)

    abp

    2017-05-18

    May 18, 2017 ... available to populations of developing countries [2-5]. In 2013, in. Western and Central Europe and ..... initiation among the infected persons in the community. Addressing stigma and educating ... Lifespan/Tufts/Brown Center for AIDS Research (P30AI042853). Tables. Table 1: Baseline characteristics of ...

  4. Research

    African Journals Online (AJOL)

    abp

    15 févr. 2016 ... présentent un Indice de Masse Corporel (IMC) normal, les autres femmes sont soit ..... In The health belief model and personal health behavior, edited by MH ... Evaluation of the Osteoporosis Health Belief Scale. Research in.

  5. Research

    African Journals Online (AJOL)

    2017-03-14

    Mar 14, 2017 ... R Ebrahim,1 MSc (Dent); H Julie,2 MPH, MCur, PhD. 1 Extended ... and research is applied to develop and sustain society.[5]. Methods .... service they want, not the service we want to give whether they want it or. Co math. G.

  6. Research

    African Journals Online (AJOL)

    abp

    2017-11-24

    Nov 24, 2017 ... Page number not for citation purposes. 1. Prevalence and determinants of common mental ..... illnesses were smoke cigarette in the last 3 months that make prevalence of tobacco use 38.2%. ..... Okasha A, Karam E.Mental health services and research in the. Arab world. Acta Psychiatrica Scandinavica.

  7. Research

    African Journals Online (AJOL)

    abp

    2014-04-21

    Apr 21, 2014 ... Prospective assessment of the risk of obstructive sleep apnea in ... Faculty of Clinical Sciences, College of Medicine, University of .... University Teaching Hospital Health Research Ethics Committee ... BANG, Berlin questionnaire and the American Society of .... The epidemiology of adult obstructive sleep.

  8. Research

    African Journals Online (AJOL)

    Research. May 2016, Vol. 8, No. 1 AJHPE 37. Students who enrol in occupational therapy (OT) at the. University of Kwa Zulu-Natal (UKZN), Durban, South Africa ... The latter may include becoming familiar with the disintegrating social systems in primary .... They also lacked the skills needed to adapt sessions and failed to ...

  9. Research

    African Journals Online (AJOL)

    ebutamanya

    2015-06-22

    Jun 22, 2015 ... collaboration with Makerere University, School of Public Health. We acknowledge The Family Health Research and Development Centre. (FHRDC) Uganda. Supported by Bill & Melinda Gates Institute for. Population & Reproductive Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, ...

  10. Research

    African Journals Online (AJOL)

    However, a focus on competence alone is inadequate to produce graduates who are capable of adapting to the changing needs of health systems. While knowledge and technical ... shared their responses to guided questions. There were three sessions; after each session the researcher aggregated participant responses ...

  11. Research

    African Journals Online (AJOL)

    abp

    2014-01-31

    Jan 31, 2014 ... by Hazarika in a population-based study in India. The researcher noted that patients' preference to the private health facilities was due mainly to their dissatisfaction with the services in the public health facilities [11]. Furthermore, the quality of the services in the private health facilities could also be a major ...

  12. Research

    African Journals Online (AJOL)

    2018-03-20

    Mar 20, 2018 ... student health professionals in various institutions, both in South Africa. (SA) and internationally. ... field include dentists, dental therapists and oral hygienists in training, .... The College of Health Sciences at UKZN has four schools: clinical ..... Journal of Emerging Trends in Educational Research and Policy ...

  13. Research

    African Journals Online (AJOL)

    abp

    2017-09-14

    Sep 14, 2017 ... Abstract. Introduction: Medical and dental students are a high-risk group for hepatitis B virus (HBV) infection which is an ... The Pan African Medical Journal - ISSN 1937-8688. ... Research ... in the College of Health Sciences and clinical students (years four to .... Hepatology International.2017 Jan; 11(1):.

  14. Research

    African Journals Online (AJOL)

    abp

    2015-01-19

    Jan 19, 2015 ... One research assistant was available to assist the learners and to answer questions while they completed the questionnaires during a classroom period. ..... PubMed | Google Scholar. 4. Hall PA, Holmqvist M, Sherry SB. Risky adolescent sexual behaviour: A psychological perspective for primary care.

  15. A Web-based database for pathology faculty effort reporting.

    Science.gov (United States)

    Dee, Fred R; Haugen, Thomas H; Wynn, Philip A; Leaven, Timothy C; Kemp, John D; Cohen, Michael B

    2008-04-01

    To ensure appropriate mission-based budgeting and equitable distribution of funds for faculty salaries, our compensation committee developed a pathology-specific effort reporting database. Principles included the following: (1) measurement should be done by web-based databases; (2) most entry should be done by departmental administration or be relational to other databases; (3) data entry categories should be aligned with funding streams; and (4) units of effort should be equal across categories of effort (service, teaching, research). MySQL was used for all data transactions (http://dev.mysql.com/downloads), and scripts were constructed using PERL (http://www.perl.org). Data are accessed with forms that correspond to fields in the database. The committee's work resulted in a novel database using pathology value units (PVUs) as a standard quantitative measure of effort for activities in an academic pathology department. The most common calculation was to estimate the number of hours required for a specific task, divide by 2080 hours (a Medicare year) and then multiply by 100. Other methods included assigning a baseline PVU for program, laboratory, or course directorship with an increment for each student or staff in that unit. With these methods, a faculty member should acquire approximately 100 PVUs. Some outcomes include (1) plotting PVUs versus salary to identify outliers for salary correction, (2) quantifying effort in activities outside the department, (3) documenting salary expenditure for unfunded research, (4) evaluating salary equity by plotting PVUs versus salary by sex, and (5) aggregating data by category of effort for mission-based budgeting and long-term planning.

  16. Fostering Integrity in Research

    Science.gov (United States)

    McNutt, M. K.

    2017-12-01

    The responsible conduct of research requires that all involved in the research enterprise - researchers, sponsors, reviewers, publishers, and communicators - adhere to a set of integrity principles to protect the public's investment. Given the increasing complexity and globalization of the research enterprise, the National Academies recently re-examined and updated its integrity recommendations for researchers in the report Fostering Integrity in Research, with sponsorship from the National Science Foundation. Major departures from the previous recommendations 25-years earlier are the recognition that practices that were previously classified as merely questionable are indeed detrimental to the responsible conduct of research. Furthermore, the report concludes that there has been insufficient effort to respond to the threats that lapses in research integrity pose to the quality of research products and the reputation of researchers as deserving of the public trust. It recommends the creation of an independent, non-profit entity dedicated to promoting research integrity by serving as a resource and clearing house for expertise, advice, materials, and best practices on fostering research integrity and responding to allegations of research misconduct.

  17. Let's Go to the Zoo: Guiding Elementary Students through Research; Ladders of Collaboration; Information Literacy and Assessment: Web Resources Too Good To Miss; Top Secret: Collaborative Efforts Really Do Make a Difference; What Is Collaboration to You?; Volunteering for Information Literacy; Getting an Early Start on Using Technology for Research; Collaborations: Working with Restrictions.

    Science.gov (United States)

    Futch, Lynn; Asper, Vicki; Repman, Judi; Tschamler, Addie; Thomas, Melody; Kearns, Jodi; Farmer, Lesley S. J.; Buzzeo, Toni

    2002-01-01

    Includes eight articles that address the role of the elementary school librarian in developing information literacy, focusing on collaboration between media specialists and classroom teachers. Highlights include student research, including a research planning sheet; Web resources on information literacy and assessment; and helping students use…

  18. The costs of parental care: a meta-analysis of the trade-off between parental effort and survival in birds.

    Science.gov (United States)

    Santos, E S A; Nakagawa, S

    2012-09-01

    A fundamental premise of life-history theory is that organisms that increase current reproductive investment suffer increased mortality. Possibly the most studied life-history phenotypic relationship is the trade-off between parental effort and survival. However, evidence supporting this trade-off is equivocal. Here, we conducted a meta-analysis to test the generality of this tenet. Using experimental studies that manipulated parental effort in birds, we show that (i) the effect of parental effort on survival was similar across species regardless of phylogeny; (ii) individuals that experienced reduced parental effort had similar survival probabilities than control individuals, regardless of sex; and (iii) males that experienced increased parental effort were less likely to survive than control males, whereas females that experienced increased effort were just as likely to survive as control females. Our results suggest that the trade-off between parental effort and survival is more complex than previously assumed. Finally, our study provides recommendations of unexplored avenues of future research into life-history trade-offs. © 2012 The Authors. Journal of Evolutionary Biology © 2012 European Society For Evolutionary Biology.

  19. Stuttering Frequency, Speech Rate, Speech Naturalness, and Speech Effort During the Production of Voluntary Stuttering.

    Science.gov (United States)

    Davidow, Jason H; Grossman, Heather L; Edge, Robin L

    2018-05-01

    Voluntary stuttering techniques involve persons who stutter purposefully interjecting disfluencies into their speech. Little research has been conducted on the impact of these techniques on the speech pattern of persons who stutter. The present study examined whether changes in the frequency of voluntary stuttering accompanied changes in stuttering frequency, articulation rate, speech naturalness, and speech effort. In total, 12 persons who stutter aged 16-34 years participated. Participants read four 300-syllable passages during a control condition, and three voluntary stuttering conditions that involved attempting to produce purposeful, tension-free repetitions of initial sounds or syllables of a word for two or more repetitions (i.e., bouncing). The three voluntary stuttering conditions included bouncing on 5%, 10%, and 15% of syllables read. Friedman tests and follow-up Wilcoxon signed ranks tests were conducted for the statistical analyses. Stuttering frequency, articulation rate, and speech naturalness were significantly different between the voluntary stuttering conditions. Speech effort did not differ between the voluntary stuttering conditions. Stuttering frequency was significantly lower during the three voluntary stuttering conditions compared to the control condition, and speech effort was significantly lower during two of the three voluntary stuttering conditions compared to the control condition. Due to changes in articulation rate across the voluntary stuttering conditions, it is difficult to conclude, as has been suggested previously, that voluntary stuttering is the reason for stuttering reductions found when using voluntary stuttering techniques. Additionally, future investigations should examine different types of voluntary stuttering over an extended period of time to determine their impact on stuttering frequency, speech rate, speech naturalness, and speech effort.

  20. Significance of promoting innovative efforts and technology transfer for industry

    Energy Technology Data Exchange (ETDEWEB)

    Rembser, J [Bundesministerium fuer Forschung und Technologie, Bonn-Bad Godesberg (Germany, F.R.)

    1978-11-01

    Technological know how and innovations will be of considerable future importance for West German industry. Changes in the reliability of sources of supply (energy, raw materials), the burden imposed on the environment by intensive industrial production and numerous private sources, and the stiffening of international competition necessitate cLoser collaboration between industry and government. Public aid in research and development efforts will assume an important role. In West Germany there is a wide variety of such governmental aids. The range extends from direct grants to enterprises for research and development work to the furnishing of advice to promote innovative efforts and technology transfer. Banks provide risk capital with governmental aid to firms trying to indroduce high-risk innovations into the market. In recent years the aim has been to provide small and medium-size firms with better access to technological know how and governmental aids.

  1. Interference from previous distraction disrupts older adults' memory.

    Science.gov (United States)

    Biss, Renée K; Campbell, Karen L; Hasher, Lynn

    2013-07-01

    Previously relevant information can disrupt the ability of older adults to remember new information. Here, the researchers examined whether prior irrelevant information, or distraction, can also interfere with older adults' memory for new information. Younger and older adults first completed a 1-back task on pictures that were superimposed with distracting words. After a delay, participants learned picture-word paired associates and memory was tested using picture-cued recall. In 1 condition (high interference), some pairs included pictures from the 1-back task now paired with new words. In a low-interference condition, the transfer list used all new items. Older adults had substantially lower cued-recall performance in the high- compared with the low-interference condition. In contrast, younger adults' performance did not vary across conditions. These findings suggest that even never-relevant information from the past can disrupt older adults' memory for new associations.

  2. Breaking the Double-Edged Sword of Effort/Trying Hard: Developmental Equilibrium and Longitudinal Relations among Effort, Achievement, and Academic Self-Concept

    Science.gov (United States)

    Marsh, Herbert W.; Pekrun, Reinhard; Lichtenfeld, Stephanie; Guo, Jiesi; Arens, A. Katrin; Murayama, Kou

    2016-01-01

    Ever since the classic research of Nicholls (1976) and others, effort has been recognized as a double-edged sword: while it might enhance achievement, it undermines academic self-concept (ASC). However, there has not been a thorough evaluation of the longitudinal reciprocal effects of effort, ASC, and achievement, in the context of modern…

  3. Food packaging cues influence taste perception and increase effort provision for a recommended snack product in children

    Directory of Open Access Journals (Sweden)

    Laura eEnax

    2015-07-01

    Full Text Available Food marketing research shows that child-directed marketing cues have pronounced effects on food preferences and consumption, but are most often placed on products with low nutritional quality. Effects of child-directed marketing strategies for healthy food products remain to be studied in more detail. Previous research suggests that effort provision explains additional variance in food choice. This study investigated the effects of packaging cues on explicit preferences and effort provision for healthy food items in elementary school children. Each of 179 children rated three, objectively identical, recommended yoghurt-cereal-fruit snacks presented with different packaging cues. Packaging cues included a plain label, a label focusing on health aspects of the product, and a label that additionally included unknown cartoon characters. The children were asked to state the subjective taste-pleasantness of the respective food items. We also used a novel approach to measure effort provision for food items in children, namely handgrip strength. Results show that packaging cues significantly induce a taste-placebo effect in 88% of the children, i.e., differences in taste ratings for objectively identical products. Taste ratings were highest for the child-directed product that included cartoon characters. Also, applied effort to receive the child-directed product was significantly higher. Our results confirm the positive effect of child-directed marketing strategies also for healthy snack food products. Using handgrip strength as a measure to determine the amount of effort children are willing to provide for a product may explain additional variance in food choice and might prove to be a promising additional research tool for field studies and the assessment of public policy interventions.

  4. Food packaging cues influence taste perception and increase effort provision for a recommended snack product in children.

    Science.gov (United States)

    Enax, Laura; Weber, Bernd; Ahlers, Maren; Kaiser, Ulrike; Diethelm, Katharina; Holtkamp, Dominik; Faupel, Ulya; Holzmüller, Hartmut H; Kersting, Mathilde

    2015-01-01

    Food marketing research shows that child-directed marketing cues have pronounced effects on food preferences and consumption, but are most often placed on products with low nutritional quality. Effects of child-directed marketing strategies for healthy food products remain to be studied in more detail. Previous research suggests that effort provision explains additional variance in food choice. This study investigated the effects of packaging cues on explicit preferences and effort provision for healthy food items in elementary school children. Each of 179 children rated three, objectively identical, recommended yogurt-cereal-fruit snacks presented with different packaging cues. Packaging cues included a plain label, a label focusing on health aspects of the product, and a label that additionally included unknown cartoon characters. The children were asked to state the subjective taste-pleasantness of the respective food items. We also used a novel approach to measure effort provision for food items in children, namely handgrip strength. Results show that packaging cues significantly induce a taste-placebo effect in 88% of the children, i.e., differences in taste ratings for objectively identical products. Taste ratings were highest for the child-directed product that included cartoon characters. Also, applied effort to receive the child-directed product was significantly higher. Our results confirm the positive effect of child-directed marketing strategies also for healthy snack food products. Using handgrip strength as a measure to determine the amount of effort children are willing to provide for a product may explain additional variance in food choice and might prove to be a promising additional research tool for field studies and the assessment of public policy interventions.

  5. Food packaging cues influence taste perception and increase effort provision for a recommended snack product in children

    Science.gov (United States)

    Enax, Laura; Weber, Bernd; Ahlers, Maren; Kaiser, Ulrike; Diethelm, Katharina; Holtkamp, Dominik; Faupel, Ulya; Holzmüller, Hartmut H.; Kersting, Mathilde

    2015-01-01

    Food marketing research shows that child-directed marketing cues have pronounced effects on food preferences and consumption, but are most often placed on products with low nutritional quality. Effects of child-directed marketing strategies for healthy food products remain to be studied in more detail. Previous research suggests that effort provision explains additional variance in food choice. This study investigated the effects of packaging cues on explicit preferences and effort provision for healthy food items in elementary school children. Each of 179 children rated three, objectively identical, recommended yogurt-cereal-fruit snacks presented with different packaging cues. Packaging cues included a plain label, a label focusing on health aspects of the product, and a label that additionally included unknown cartoon characters. The children were asked to state the subjective taste-pleasantness of the respective food items. We also used a novel approach to measure effort provision for food items in children, namely handgrip strength. Results show that packaging cues significantly induce a taste-placebo effect in 88% of the children, i.e., differences in taste ratings for objectively identical products. Taste ratings were highest for the child-directed product that included cartoon characters. Also, applied effort to receive the child-directed product was significantly higher. Our results confirm the positive effect of child-directed marketing strategies also for healthy snack food products. Using handgrip strength as a measure to determine the amount of effort children are willing to provide for a product may explain additional variance in food choice and might prove to be a promising additional research tool for field studies and the assessment of public policy interventions. PMID:26191012

  6. Mechanisms of Biliary Plastic Stent Occlusion and Efforts at Prevention

    Directory of Open Access Journals (Sweden)

    Chang-Il Kwon

    2016-03-01

    Full Text Available Biliary stenting via endoscopic retrograde cholangiopancreatography has greatly improved the quality of patient care over the last 30 years. Plastic stent occlusion limits the life span of such stents. Attempts to improve plastic stent patency duration have mostly failed. Metal stents (self-expandable metal stents [SEMSs] have therefore replaced plastic stents, especially for malignant biliary strictures. SEMS are at least 10 times more expensive than plastic stents. In this focused review, we will discuss basic mechanisms of plastic stent occlusion, along with a systematic summary of previous efforts and related studies to improve stent patency and potential new techniques to overcome existing limitations.

  7. Instruction Emphasizing Effort Improves Physics Problem Solving

    Science.gov (United States)

    Li, Daoquan

    2012-01-01

    Effectively using strategies to solve complex problems is an important educational goal and is implicated in successful academic performance. However, people often do not spontaneously use the effective strategies unless they are motivated to do so. The present study was designed to test whether educating students about the importance of effort in…

  8. Student Effort, Consistency, and Online Performance

    Science.gov (United States)

    Patron, Hilde; Lopez, Salvador

    2011-01-01

    This paper examines how student effort, consistency, motivation, and marginal learning, influence student grades in an online course. We use data from eleven Microeconomics courses taught online for a total of 212 students. Our findings show that consistency, or less time variation, is a statistically significant explanatory variable, whereas…

  9. Net benefits of wildfire prevention education efforts

    Science.gov (United States)

    Jeffrey P. Prestemon; David T. Butry; Karen L. Abt; Ronda Sutphen

    2010-01-01

    Wildfire prevention education efforts involve a variety of methods, including airing public service announcements, distributing brochures, and making presentations, which are intended to reduce the occurrence of certain kinds of wildfires. A Poisson model of preventable Florida wildfires from 2002 to 2007 by fire management region was developed. Controlling for...

  10. Has Malaysia's antidrug effort been effective?

    Science.gov (United States)

    Scorzelli, J F

    1992-01-01

    It is a common belief that a massive effort in law enforcement, preventive education and rehabilitation will result in the elimination of a country's drug problem. Based on this premise. Malaysia in 1983 implemented such a multifaceted anti-drug strategy, and the results of a 1987 study by the author suggested that Malaysia's effort had begun to contribute to a steady decrease in the number of identified drug abusers. Although the number of drug-addicted individuals declined, the country's recidivism rates were still high. Because of this high relapse rate, Malaysia expanded their rehabilitation effort and developed a community transition program. In order to determine the impact of these changes on the country's battle against drug abuse, a follow-up study was conducted in 1990. The results of this study did not clearly demonstrate that the Malaysian effort had been successful in eliminating the problem of drug abuse, and raised some questions concerning the effectiveness of the country's drug treatment programs.

  11. Phase transitions in least-effort communications

    International Nuclear Information System (INIS)

    Prokopenko, Mikhail; Ay, Nihat; Obst, Oliver; Polani, Daniel

    2010-01-01

    We critically examine a model that attempts to explain the emergence of power laws (e.g., Zipf's law) in human language. The model is based on the principle of least effort in communications—specifically, the overall effort is balanced between the speaker effort and listener effort, with some trade-off. It has been shown that an information-theoretic interpretation of this principle is sufficiently rich to explain the emergence of Zipf's law in the vicinity of the transition between referentially useless systems (one signal for all referable objects) and indexical reference systems (one signal per object). The phase transition is defined in the space of communication accuracy (information content) expressed in terms of the trade-off parameter. Our study explicitly solves the continuous optimization problem, subsuming a recent, more specific result obtained within a discrete space. The obtained results contrast Zipf's law found by heuristic search (that attained only local minima) in the vicinity of the transition between referentially useless systems and indexical reference systems, with an inverse-factorial (sub-logarithmic) law found at the transition that corresponds to global minima. The inverse-factorial law is observed to be the most representative frequency distribution among optimal solutions

  12. The Galileo Teacher Training Program Global Efforts

    Science.gov (United States)

    Doran, R.; Pennypacker, C.; Ferlet, R.

    2012-08-01

    The Galileo Teacher Training Program (GTTP) successfully named representatives in nearly 100 nations in 2009, the International Year of Astronomy (IYA2009). The challenge had just begun. The steps ahead are how to reach educators that might benefit from our program and how to help build a more fair and science literate society, a society in which good tools and resources for science education are not the privilege of a few. From 2010 on our efforts have been to strengthen the newly formed network and learn how to equally help educators and students around the globe. New partnerships with other strong programs and institutions are being formed, sponsorship schemes being outlined, new tools and resources being publicized, and on-site and video conference training conducted all over the world. Efforts to officially accredit a GTTP curriculum are on the march and a stronger certification process being outlined. New science topics are being integrated in our effort and we now seek to discuss the path ahead with experts in this field and the community of users, opening the network to all corners of our beautiful blue dot. The main aim of this article is to open the discussion regarding the urgent issue of how to reawaken student interest in science, how to solve the gender inequality in science careers, and how to reach the underprivileged students and open to them the same possibilities. Efforts are in strengthening the newly formed network and learning how to equally help educators and students around the globe.

  13. Effort - Final technical report on task 3

    DEFF Research Database (Denmark)

    Bay, Niels; Henningsen, Poul; Eriksen, Morten

    The present report is documentation for the work carried out at DTU on the Brite/Euram project No. BE96-3340, contract No. BRPR-CT97-0398, with the title Enhanced Framework for forging design using reliable three-dimensional simulation (EFFORTS). The objective of task 3 is to determine data...

  14. Workplace High Tech Spurs Retraining Efforts.

    Science.gov (United States)

    Davis, Dwight B.

    1984-01-01

    Discusses who should provide training for displaced workers who need new skills. Areas examined include: (1) the need for retraining; (2) current corporate efforts; (3) agreements in the automotive industry; (4) job quality; (5) the federal government's role; and (6) federal legislation related to the problem. (JN)

  15. Testosterone and reproductive effort in male primates.

    Science.gov (United States)

    Muller, Martin N

    2017-05-01

    Considerable evidence suggests that the steroid hormone testosterone mediates major life-history trade-offs in vertebrates, promoting mating effort at the expense of parenting effort or survival. Observations from a range of wild primates support the "Challenge Hypothesis," which posits that variation in male testosterone is more closely associated with aggressive mating competition than with reproductive physiology. In both seasonally and non-seasonally breeding species, males increase testosterone production primarily when competing for fecund females. In species where males compete to maintain long-term access to females, testosterone increases when males are threatened with losing access to females, rather than during mating periods. And when male status is linked to mating success, and dependent on aggression, high-ranking males normally maintain higher testosterone levels than subordinates, particularly when dominance hierarchies are unstable. Trade-offs between parenting effort and mating effort appear to be weak in most primates, because direct investment in the form of infant transport and provisioning is rare. Instead, infant protection is the primary form of paternal investment in the order. Testosterone does not inhibit this form of investment, which relies on male aggression. Testosterone has a wide range of effects in primates that plausibly function to support male competitive behavior. These include psychological effects related to dominance striving, analgesic effects, and effects on the development and maintenance of the armaments and adornments that males employ in mating competition. Copyright © 2016 Elsevier Inc. All rights reserved.

  16. Reasonable limits to radiation protection efforts

    International Nuclear Information System (INIS)

    Gonen, Y.G.

    1982-01-01

    It is shown that change in life expectancy (ΔLE) is an improved estimate for risks and safety efforts, reflecting the relevant social goal. A cost-effectiveness index, safety investment/ΔLE, is defined. The harm from low level radiation is seen as a reduction of life expectancy instead of an increased probability of contracting cancer. (author)

  17. Measuring progress of collaborative action in a community health effort

    OpenAIRE

    Vicki L. Collie-Akers; Stephen B. Fawcett; Jerry A. Schultz

    2013-01-01

    OBJECTIVE: To measure the progress made by the collaborative actions of multisectorial partners in a community health effort using a systematic method to document and evaluate community/system changes over time. METHODS: This was a community-based participatory research project engaging community partners of the Latino Health for All Coalition, which based on the Health for All model, addresses health inequity in a low-income neighborhood in Kansas City, Kansas, United States of America. Guid...

  18. Radon anomalies prior to earthquakes (1). Review of previous studies

    International Nuclear Information System (INIS)

    Ishikawa, Tetsuo; Tokonami, Shinji; Yasuoka, Yumi; Shinogi, Masaki; Nagahama, Hiroyuki; Omori, Yasutaka; Kawada, Yusuke

    2008-01-01

    The relationship between radon anomalies and earthquakes has been studied for more than 30 years. However, most of the studies dealt with radon in soil gas or in groundwater. Before the 1995 Hyogoken-Nanbu earthquake, an anomalous increase of atmospheric radon was observed at Kobe Pharmaceutical University. The increase was well fitted with a mathematical model related to earthquake fault dynamics. This paper reports the significance of this observation, reviewing previous studies on radon anomaly before earthquakes. Groundwater/soil radon measurements for earthquake prediction began in 1970's in Japan as well as foreign countries. One of the most famous studies in Japan is groundwater radon anomaly before the 1978 Izu-Oshima-kinkai earthquake. We have recognized the significance of radon in earthquake prediction research, but recently its limitation was also pointed out. Some researchers are looking for a better indicator for precursors; simultaneous measurements of radon and other gases are new trials in recent studies. Contrary to soil/groundwater radon, we have not paid much attention to atmospheric radon before earthquakes. However, it might be possible to detect precursors in atmospheric radon before a large earthquake. In the next issues, we will discuss the details of the anomalous atmospheric radon data observed before the Hyogoken-Nanbu earthquake. (author)

  19. Can previous acid etching increase the bond strength of a self-etching primer adhesive to enamel?

    Directory of Open Access Journals (Sweden)

    Ana Paula Morales Cobra Carvalho

    2009-06-01

    Full Text Available Because a greater research effort has been directed to analyzing the adhesive effectiveness of self etch primers to dentin, the aim of this study was to evaluate, by microtensile testing, the bond strength to enamel of a composite resin combined with a conventional adhesive system or with a self-etching primer adhesive, used according to its original prescription or used with previous acid etching. Thirty bovine teeth were divided into 3 groups with 10 teeth each (n= 10. In one of the groups, a self-etching primer (Clearfil SE Bond - Kuraray was applied in accordance with the manufacturer's instructions and, in the other, it was applied after previous acid etching. In the third group, a conventional adhesive system (Scotchbond Multipurpose Plus - 3M-ESPE was applied in accordance with the manufacturer's instructions. The results obtained by analysis of variance revealed significant differences between the adhesive systems (F = 22.31. The self-etching primer (Clearfil SE Bond presented lower enamel bond strength values than the conventional adhesive system (Scotchbond Multipurpose Plus (m = 39.70 ± 7.07 MPa both when used according to the original prescription (m = 27.81 ± 2.64 MPa and with previous acid etching (m = 25.08 ± 4.92 MPa.

  20. Student Effort, Consistency and Online Performance

    Directory of Open Access Journals (Sweden)

    Hilde Patron

    2011-07-01

    Full Text Available This paper examines how student effort, consistency, motivation, and marginal learning, influence student grades in an online course. We use data from eleven Microeconomics courses taught online for a total of 212 students. Our findings show that consistency, or less time variation, is a statistically significant explanatory variable, whereas effort, or total minutes spent online, is not. Other independent variables include GPA and the difference between a pre-test and a post-test. The GPA is used as a measure of motivation, and the difference between a post-test and pre-test as marginal learning. As expected, the level of motivation is found statistically significant at a 99% confidence level, and marginal learning is also significant at a 95% level.

  1. Non-proliferation efforts in South Asia

    International Nuclear Information System (INIS)

    Chellaney, B.

    1994-01-01

    Southern Asia is one of the most volatile regions in the world because of inter-State and intra-State conflicts. Security in the region highly depends on the rival capabilities of the involved states, Pakistan, India, China. Increased Confidence building and nuclear transparency are becoming more significant issues in attaining stability in the region, although non-proliferation efforts in this region have attained little headway

  2. Some recent efforts toward high density implosions

    International Nuclear Information System (INIS)

    McClellan, G.E.

    1980-01-01

    Some recent Livermore efforts towards achieving high-density implosions are presented. The implosion dynamics necessary to compress DT fuel to 10 to 100 times liquid density are discussed. Methods of diagnosing the maximum DT density for a specific design are presented along with results to date. The dynamics of the double-shelled target with an exploding outer shell are described, and some preliminary experimental results are presented

  3. Evaluative language, cognitive effort and attitude change.

    OpenAIRE

    van der Pligt, J.; van Schie, E.C.M.; Martijn, C.

    1994-01-01

    Tested the hypotheses that evaluatively biased language influences attitudes and that the magnitude and persistence of attitude change depends on the amount of cognitive effort. 132 undergraduates participated in the experiment, which used material focusing on the issue of restricting adolescent driving over the weekends to reduce the number of fatal traffic accidents. Results indicate that evaluatively biased language can affect attitudes. Using words that evaluate the pro-position positivel...

  4. Efforts to identify spore forming bacillus

    Energy Technology Data Exchange (ETDEWEB)

    Zuleiha, M.S.; Hilmy, N. (National Atomic Energy Agency, Jakarta (Indonesia). Pasar Djumat Research Centre)

    1982-04-01

    Efforts to identify 47 species of radioresistant spore forming bacillus sp. isolated from locally produced medical devices have been carried out. The identifications was conducted using 19 kinds of biochemical tests and compared to species to bacillus subtilis W. T.; bacillus pumilus E 601 and bacillus sphaericus Csub(I)A. The results showed that bacillus sp. examined could be divided into 6 groups, i.e. bacillus cereus; bacillus subtilis; bacillus stearothermophylus; bacillus coagulans; bacillus sphaericus and bacillus circulans.

  5. Efforts to identify spore forming bacillus

    International Nuclear Information System (INIS)

    Zuleiha, M.S.; Hilmy, Nazly

    1982-01-01

    Efforts to identify 47 species of radioresistant spore forming bacillus sp. isolated from locally produced medical devices have been carried out. The identifications was conducted using 19 kinds of biochemical tests and compared to species to bacillus subtilis W. T.; bacillus pumilus E 601 and bacillus sphaericus Csub(I)A. The results showed that bacillus sp. examined could be divided into 6 groups, i.e. bacillus cereus; bacillus subtilis; bacillus stearothermophylus; bacillus coagulans; bacillus sphaericus and bacillus circulans. (author)

  6. Duke Power's liquid radwaste processing improvement efforts

    International Nuclear Information System (INIS)

    Baker, R.E. Jr.; Bramblett, J.W.

    1995-01-01

    The rising cost of processing liquid radwaste and industry efforts to reduce offsite isotopic contributions has drawn greater attention to the liquid radwaste area. Because of economic pressures to reduce cost and simultaneously improve performance, Duke Power has undertaken a wide ranging effort to cost effectively achieve improvements in the liquid radwaste processing area. Duke Power has achieved significant reductions over recent years in the release of curies to the environment from the Liquid Radwaste Treatmentt systems at its Catawba, McGuire, and Oconee stations. System wide site curie reductions of 78% have been achieved in a 3 year period. These curie reductions have been achieved while simultaneously reducing the amount of media used to accomplish treatment. The curie and media usage reductions have been achieved at low capital cost expenditures. A large number of approaches and projects have been used to achieve these curie and media usage reductions. This paper will describe the various projects and the associated results for Duke Power's processing improvement efforts. The subjects/projects which will be described include: (1) Cooperative philosophy between stations (2) Source Control (3) Processing Improvements (4) Technology Testing

  7. To boost or to CRUNCH? Effect of effortful encoding on episodic memory in older adults is dependent on executive functioning.

    Directory of Open Access Journals (Sweden)

    Li Fu

    Full Text Available It is essential to develop effective interventions aimed at ameliorating age-related cognitive decline. Previous studies found that effortful encoding benefits episodic memory in older adults. However, to date it is unclear whether this benefit is different for individuals with strong versus weak executive functioning (EF. Fifty-one older adults were recruited and divided into low (N = 26 and high (N = 25 functioning groups, based on their EF capacity. All participants performed a semantic and a perceptual incidental encoding task. Each encoding task was performed under four difficulty levels to establish different effort levels. Encoding was followed by a recognition task. Results showed that the high EF group benefitted from increased effort in both tasks. However, the low EF group only showed a beneficial effect under low levels of effort. Results are consistent with the Compensation-Related Utilization of Neural Circuits Hypothesis (CRUNCH and suggest that future research directed at developing efficient memory strategies to reduce negative cognitive aging effects should take individual cognitive differences among older adults into account, such as differences in EF.

  8. Urethrotomy has a much lower success rate than previously reported.

    Science.gov (United States)

    Santucci, Richard; Eisenberg, Lauren

    2010-05-01

    We evaluated the success rate of direct vision internal urethrotomy as a treatment for simple male urethral strictures. A retrospective chart review was performed on 136 patients who underwent urethrotomy from January 1994 through March 2009. The Kaplan-Meier method was used to analyze stricture-free probability after the first, second, third, fourth and fifth urethrotomy. Patients with complex strictures (36) were excluded from the study for reasons including previous urethroplasty, neophallus or previous radiation, and 24 patients were lost to followup. Data were available for 76 patients. The stricture-free rate after the first urethrotomy was 8% with a median time to recurrence of 7 months. For the second urethrotomy stricture-free rate was 6% with a median time to recurrence of 9 months. For the third urethrotomy stricture-free rate was 9% with a median time to recurrence of 3 months. For procedures 4 and 5 stricture-free rate was 0% with a median time to recurrence of 20 and 8 months, respectively. Urethrotomy is a popular treatment for male urethral strictures. However, the performance characteristics are poor. Success rates were no higher than 9% in this series for first or subsequent urethrotomy during the observation period. Most of the patients in this series will be expected to experience failure with longer followup and the expected long-term success rate from any (1 through 5) urethrotomy approach is 0%. Urethrotomy should be considered a temporizing measure until definitive curative reconstruction can be planned. 2010 American Urological Association Education and Research, Inc. Published by Elsevier Inc. All rights reserved.

  9. Impact of previously disadvantaged land-users on sustainable ...

    African Journals Online (AJOL)

    Impact of previously disadvantaged land-users on sustainable agricultural ... about previously disadvantaged land users involved in communal farming systems ... of input, capital, marketing, information and land use planning, with effect on ...

  10. 22 CFR 40.91 - Certain aliens previously removed.

    Science.gov (United States)

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Certain aliens previously removed. 40.91... IMMIGRANTS UNDER THE IMMIGRATION AND NATIONALITY ACT, AS AMENDED Aliens Previously Removed § 40.91 Certain aliens previously removed. (a) 5-year bar. An alien who has been found inadmissible, whether as a result...

  11. GLCF: Research

    Science.gov (United States)

    Global Land Cover Facility About GLCF Research Publications Data & Products Gallery Library Services Contact Site Map Go Research The Global Land Cover Facility is a research center focusing on the GLCF in developing forest change products. Past research efforts were directed at boreal forests in

  12. Pioneering efforts to control AIDS. Review: IHO.

    Science.gov (United States)

    Chatterji, A; Sehgal, K

    1995-01-01

    The Indian Health Organisation (IHO) is a nongovernmental organization based in Bombay with more than 12 years experience in HIV/AIDS prevention and control efforts. It has attacked ignorance and prejudice via communication efforts. IHO has created a bond with some hospital systems of Bombay. IHO disseminated information about HIV/AIDS in Bombay's red light districts and has bridged the gap between the city's medical establishment and the community most in need. IHO's aggressive street-level fighting in a sector replete with sensitive issues has somewhat isolated it from mainstream national NGOs involved in HIV/AIDS education and control as well as from the medical establishment and potential partners. IHO funds have been reduced, forcing IHO to reduce intervention programs and responses to field demands. It suffers from a high rate of turnover among middle management staff. IHO's chief advantage is its confidence gained over the past 12 years. IHO has clearly delineated the direction it wants to go: care and support programs for persons affected by HIV/AIDS and for commercial sex workers to allow them to quit prostitution, orphan care, and development of training institutions for the education and motivation of medical personnel on HIV/AIDS care and prevention. It plans to build a hospice for AIDS patients and orphans and a training center. Training activities will vary from one-week orientation programs to three-month certificate courses for medical workers, NGOs, and managers from the commercial sector. IHO is prepared to share its experiences in combating HIV/AIDS in Bombay in a team effort. As official and bilateral funding has been decreasing, IHO has targeted industry for funding. Industry has responded, which enables IHO to sustain its core programs and approaches. IHO observations show a decrease in the number of men visiting red-light districts. IHO enjoys a positive relationship with Bombay's media reporting on AIDS.

  13. Economic growth, biodiversity loss and conservation effort.

    Science.gov (United States)

    Dietz, Simon; Adger, W Neil

    2003-05-01

    This paper investigates the relationship between economic growth, biodiversity loss and efforts to conserve biodiversity using a combination of panel and cross section data. If economic growth is a cause of biodiversity loss through habitat transformation and other means, then we would expect an inverse relationship. But if higher levels of income are associated with increasing real demand for biodiversity conservation, then investment to protect remaining diversity should grow and the rate of biodiversity loss should slow with growth. Initially, economic growth and biodiversity loss are examined within the framework of the environmental Kuznets hypothesis. Biodiversity is represented by predicted species richness, generated for tropical terrestrial biodiversity using a species-area relationship. The environmental Kuznets hypothesis is investigated with reference to comparison of fixed and random effects models to allow the relationship to vary for each country. It is concluded that an environmental Kuznets curve between income and rates of loss of habitat and species does not exist in this case. The role of conservation effort in addressing environmental problems is examined through state protection of land and the regulation of trade in endangered species, two important means of biodiversity conservation. This analysis shows that the extent of government environmental policy increases with economic development. We argue that, although the data are problematic, the implications of these models is that conservation effort can only ever result in a partial deceleration of biodiversity decline partly because protected areas serve multiple functions and are not necessarily designated to protect biodiversity. Nevertheless institutional and policy response components of the income biodiversity relationship are important but are not well captured through cross-country regression analysis.

  14. Effect of fishing effort on catch rate and catchability of largemouth bass in small impoundments

    Science.gov (United States)

    Wegener, M. G.; Schramm, Harold; Neal, J. W.; Gerard, P.D.

    2018-01-01

    Largemouth bass Micropterus salmoides (Lacepède) catch rates decline with sustained fishing effort, even without harvest. It is unclear why declines in catch rate occur, and little research has been directed at how to improve catch rate. Learning has been proposed as a reason for declining catch rate, but has never been tested on largemouth bass. If catch rate declines because fish learn to avoid lures, periods of no fishing could be a management tool for increasing catch rate. In this study, six small impoundments with established fish populations were fished for two May to October fishing seasons to evaluate the effect of fishing effort on catch rate. Closed seasons were implemented to test whether a 2‐month period of no fishing improved catch rates and to determine whether conditioning from factors other than being captured reduced catch rate. Mixed‐model analysis indicated catch rate and catchability declined throughout the fishing season. Catch rate and catchability increased after a 2‐month closure but soon declined to the lowest levels of the fishing season. These changes in catch rate and catchability support the conclusion of learned angler avoidance, but sustained catchability of fish not previously caught does not support that associative or social learning affected catchability.

  15. Determining root correspondence between previously and newly detected objects

    Science.gov (United States)

    Paglieroni, David W.; Beer, N Reginald

    2014-06-17

    A system that applies attribute and topology based change detection to networks of objects that were detected on previous scans of a structure, roadway, or area of interest. The attributes capture properties or characteristics of the previously detected objects, such as location, time of detection, size, elongation, orientation, etc. The topology of the network of previously detected objects is maintained in a constellation database that stores attributes of previously detected objects and implicitly captures the geometrical structure of the network. A change detection system detects change by comparing the attributes and topology of new objects detected on the latest scan to the constellation database of previously detected objects.

  16. Educational Outreach Efforts at the NNDC

    International Nuclear Information System (INIS)

    Holden, N.E.

    2014-01-01

    Isotopes and nuclides are important in our everyday life. The general public and most students are never exposed to the concepts of stable and radioactive isotopes/nuclides. The National Nuclear Data Center (NNDC) is involved in an international project to develop a Periodic Table of the Isotopes for the educational community to illustrate the importance of isotopes and nuclides in understanding the world around us. This effort should aid teachers in introducing these concepts to students from the high school to the graduate school level

  17. Effort variation regularization in sound field reproduction

    DEFF Research Database (Denmark)

    Stefanakis, Nick; Jacobsen, Finn; Sarris, Ioannis

    2010-01-01

    In this paper, active control is used in order to reproduce a given sound field in an extended spatial region. A method is proposed which minimizes the reproduction error at a number of control positions with the reproduction sources holding a certain relation within their complex strengths......), and adaptive wave field synthesis (AWFS), both under free-field conditions and in reverberant rooms. It is shown that effort variation regularization overcomes the problems associated with small spaces and with a low ratio of direct to reverberant energy, improving thus the reproduction accuracy...

  18. Multipartite Entanglement Detection with Minimal Effort

    Science.gov (United States)

    Knips, Lukas; Schwemmer, Christian; Klein, Nico; Wieśniak, Marcin; Weinfurter, Harald

    2016-11-01

    Certifying entanglement of a multipartite state is generally considered a demanding task. Since an N qubit state is parametrized by 4N-1 real numbers, one might naively expect that the measurement effort of generic entanglement detection also scales exponentially with N . Here, we introduce a general scheme to construct efficient witnesses requiring a constant number of measurements independent of the number of qubits for states like, e.g., Greenberger-Horne-Zeilinger states, cluster states, and Dicke states. For four qubits, we apply this novel method to experimental realizations of the aforementioned states and prove genuine four-partite entanglement with two measurement settings only.

  19. Influence of Previous Knowledge in Torrance Tests of Creative Thinking

    Directory of Open Access Journals (Sweden)

    María Aranguren

    2015-07-01

    Full Text Available The aim of this work is to analyze the influence of study field, expertise and recreational activities participation in Torrance Tests of Creative Thinking (TTCT, 1974 performance. Several hypotheses were postulated to explore the possible effects of previous knowledge in TTCT verbal and TTCT figural university students’ outcomes. Participants in this study included 418 students from five study fields: Psychology;Philosophy and Literature, Music; Engineering; and Journalism and Advertising (Communication Sciences. Results found in this research seem to indicate that there in none influence of the study field, expertise and recreational activities participation in neither of the TTCT tests. Instead, the findings seem to suggest some kind of interaction between certain skills needed to succeed in specific studies fields and performance on creativity tests, such as the TTCT. These results imply that TTCT is a useful and valid instrument to measure creativity and that some cognitive process involved in innovative thinking can be promoted using different intervention programs in schools and universities regardless the students study field.

  20. Economics of fusion research

    International Nuclear Information System (INIS)

    1977-01-01

    This report provides the results of a study of methods of economic analysis applied to the evaluation of fusion research. The study recognizes that a hierarchy of economic analyses of research programs exists: standard benefit-cost analysis, expected value of R and D information, and expected utility analysis. It is shown that standard benefit-cost analysis, as commonly applied to research programs, is inadequate for the evaluation of a high technology research effort such as fusion research. A methodology for performing an expected value analysis is developed and demonstrated and an overview of an approach to perform an expected utility analysis of fusion research is presented. In addition, a potential benefit of fusion research, not previously identified, is discussed and rough estimates of its magnitude are presented. This benefit deals with the effect of a fusion research program on optimal fossil fuel consumption patterns. The results of this study indicate that it is both appropriate and possible to perform an expected value analysis of fusion research in order to assess the economics of a fusion research program. The results indicate further that the major area of benefits of fusion research is likely due to the impact of a fusion research program on optimal fossil fuel consumption patterns and it is recommended that this benefit be included in future assessments of fusion research economics

  1. Economics of fusion research

    Energy Technology Data Exchange (ETDEWEB)

    None, None

    1977-10-15

    This report provides the results of a study of methods of economic analysis applied to the evaluation of fusion research. The study recognizes that a hierarchy of economic analyses of research programs exists: standard benefit-cost analysis, expected value of R and D information, and expected utility analysis. It is shown that standard benefit-cost analysis, as commonly applied to research programs, is inadequate for the evaluation of a high technology research effort such as fusion research. A methodology for performing an expected value analysis is developed and demonstrated and an overview of an approach to perform an expected utility analysis of fusion research is presented. In addition, a potential benefit of fusion research, not previously identified, is discussed and rough estimates of its magnitude are presented. This benefit deals with the effect of a fusion research program on optimal fossil fuel consumption patterns. The results of this study indicate that it is both appropriate and possible to perform an expected value analysis of fusion research in order to assess the economics of a fusion research program. The results indicate further that the major area of benefits of fusion research is likely due to the impact of a fusion research program on optimal fossil fuel consumption patterns and it is recommended that this benefit be included in future assessments of fusion research economics.

  2. International Efforts for the Nuclear Security

    International Nuclear Information System (INIS)

    Yoo, Ho Sik; Kwak, Sung Woo; Lee, Ho Jin; Shim, Hye Won; Lee, Jong Uk

    2005-01-01

    Many concerns have been focused on the nuclear security since the 9.11. With increasing the threat related to nuclear material and nuclear facilities, the demand of strengthening the international physical protection system has been raised. Along with this, the international communities are making their efforts to increase nuclear security. The agreement of revising the 'Convention on Physical Protection of Nuclear Materials'(hereafter, CPPNM), which was held in Vienna on the July of 2005, was one of these efforts. U.N is also preparing the 'International Convention for the Suppression of Acts of Nuclear Terrorism' to show its firm resolution against nuclear terror. It is important to understand what measures should be taken to meet the international standard for establishing national physical protection system. To do this, international trend on the physical protection system such as CPPNM and U.N. convention should be followed. This paper explains about the content of the CPPNM and U.N convention. They will be helpful to consolidate the physical protection system in Korea

  3. Sidoarjo mudflow phenomenon and its mitigation efforts

    Science.gov (United States)

    Wibowo, H. T.; Williams, V.

    2009-12-01

    Hot mud first erupted in Siring village, Porong, Sidoarjo May 29th 2006. The mud first appeared approximately 200 meters from Banjarpanji-1 gas-drilling well. The mud volume increased day by day, from 5000 cubic meters per day on June 2006 to 50,000 cubic meters per day during the last of 2006, and then increased to 100,000-120,000 cubic meters per day during 2007. Flow still continues at a high rate. Moreover, as the water content has gone down, the clast content has gone up. Consequently, there is now the threat of large amounts of solid material being erupted throughout the area. Also, there is the issue of subsurface collapse and ground surface subsidence. The Indonesian government has set up a permanent team to support communities affected by the mudflow that has swamped a number of villages near LUSI. Toll roads, railway tracks and factories also have been submerged and over 35,000 people have been displaced to date. The Sidoarjo Mudflow Mitigation Agency [SMMA, BPLS (Indonesia)] replaces a temporary team called National Team PSLS which was installed for seven months and ended their work on 7 April 2007. BPLS was set up by Presidential Regulation No. 14 / 2007, and it will have to cover the costs related to the social impact of the disaster, especially outside the swamped area. BPLS is the central government institution designated to handle the disaster by coordination with both the drilling company and local (provincial and district) governments. It takes a comprehensive, integrated and holistic approach for its mission and challenges. Those are: 1) How to stop the mudflow, 2) How to mitigate the impacts of the mudflow, and 3) How to minimize the social, economic, environmental impacts, and infrastructure impacts. The mudflow mitigation efforts were constrained by dynamic geology conditions, as well as resistance to certain measures by residents of impacted areas. Giant dykes were built to retain the spreading mud, and the mudflow from the main vent was

  4. Partnering Against Cancer Today: A Blueprint for Coordinating Efforts Through Communication Science

    Science.gov (United States)

    2013-01-01

    One of the hallmarks of the communication revolution over the past decade has been its support for participation, whether that be in the active engagement of patients searching the Web for answers to vital health questions, or in the collective energies of self-organizing communities through social media. At the same time, some of the major obstacles to achieving a full and equitable reach of evidence-based cancer control knowledge have been traced back to discontinuities in communication either within clinical care or the broader public awareness system. Communication scientists from the National Cancer Institute, the Centers for Disease Control and Prevention, and the American Cancer Society joined forces in 2010 to investigate ways in which communication science can be used to improve coordination and enhance participation in cancer control for the nation. From 2010 to 2013, the three organizations worked together in 1) convening two meetings designed to assess the status of funded research in communication science, 2) completing a systematic review of literature published over the previous 10 years, and 3) authoring a blueprint for coordinated efforts using the implications of communication science. The blueprint consists of three major goals: first, to identify high-yield targets of opportunity using the health impact pyramid articulated by Centers for Disease Control and Prevention Director, Thomas Frieden; second, to leverage opportunities within the new communication environment, including the opportunities catalyzed by national efforts to create an infrastructure for evidence implementation through health information technology; and third, to assist in coordinating efforts across collaborative entities through participative media. PMID:24395998

  5. Measuring progress of collaborative action in a community health effort

    Directory of Open Access Journals (Sweden)

    Vicki L. Collie-Akers

    2013-12-01

    Full Text Available OBJECTIVE: To measure the progress made by the collaborative actions of multisectorial partners in a community health effort using a systematic method to document and evaluate community/system changes over time. METHODS: This was a community-based participatory research project engaging community partners of the Latino Health for All Coalition, which based on the Health for All model, addresses health inequity in a low-income neighborhood in Kansas City, Kansas, United States of America. Guided by three research questions regarding the extent to which the Coalition catalyzed change, intensity of change, and how to visually display change, data were collected on community/system changes implemented by the community partners from 2009-2012. These changes were characterized and rated according to intensity (event duration, population reach, and strategy and by other categories, such as social determinant of health mechanism and sector. RESULTS: During the 4-year study period, the Coalition implemented 64 community/system changes. These changes were aligned with the Coalition's primary goals of healthy nutrition, physical activity, and access to health screenings. Community/system efforts improved over time, becoming longer in duration and reaching more of the population. CONCLUSIONS: Although evidence of its predictive validity awaits further research, this method for documenting and characterizing community/system changes enables community partners to see progress made by their health initiatives.

  6. The Role of Student-Teacher Ratio in Parents' Perceptions of Schools' Engagement Efforts

    Science.gov (United States)

    Rodriguez, Raymond J.; Elbaum, Batya

    2014-01-01

    Research suggests a positive relationship between schools' efforts to engage parents and parents' involvement in their child's education. The authors investigated school socioeconomic status, school size, grade level, and student-teacher ratio as predictors of schools' efforts to engage parents of students receiving special education services. The…

  7. Living systematic reviews: 2. Combining human and machine effort.

    Science.gov (United States)

    Thomas, James; Noel-Storr, Anna; Marshall, Iain; Wallace, Byron; McDonald, Steven; Mavergames, Chris; Glasziou, Paul; Shemilt, Ian; Synnot, Anneliese; Turner, Tari; Elliott, Julian

    2017-11-01

    New approaches to evidence synthesis, which use human effort and machine automation in mutually reinforcing ways, can enhance the feasibility and sustainability of living systematic reviews. Human effort is a scarce and valuable resource, required when automation is impossible or undesirable, and includes contributions from online communities ("crowds") as well as more conventional contributions from review authors and information specialists. Automation can assist with some systematic review tasks, including searching, eligibility assessment, identification and retrieval of full-text reports, extraction of data, and risk of bias assessment. Workflows can be developed in which human effort and machine automation can each enable the other to operate in more effective and efficient ways, offering substantial enhancement to the productivity of systematic reviews. This paper describes and discusses the potential-and limitations-of new ways of undertaking specific tasks in living systematic reviews, identifying areas where these human/machine "technologies" are already in use, and where further research and development is needed. While the context is living systematic reviews, many of these enabling technologies apply equally to standard approaches to systematic reviewing. Copyright © 2017 The Authors. Published by Elsevier Inc. All rights reserved.

  8. STAR Infrastructure Database: An effort to know each other

    Energy Technology Data Exchange (ETDEWEB)

    Mora, J.C.; Real, Almudena [Centro de Investigaciones Energeticas, Medioambientales y Tecnologicas - CIEMAT (Spain); Vesterbacka, Pia; Outola, Iisa [STUK - Radiation and Nuclear Safety Authority (Finland); Barnett, Catherine; Beresford, Nick [Natural Environment Research Council - NERC-CEH (United Kingdom); Bradshaw, Clare [Stockholm University (Sweden); Skipperud, Lindis [Norwegian University of Life Sciences - UMB (Norway); Wilrodt, Christine; Steiner, Martin [Federal Office for Radiation Protection - BfS (Germany); Vanhoudt, Nathalie [Belgian Nuclear Research Centre SCK-CEN (Belgium); Komperoed, Mari [Norwegian Radiation Protection Authority - NRPA (Norway); Gurriaran, Rodolfo; Gilbin, Rodolphe; Hinton, Thomas [Institut de Radioprotection et de Surete Nucleaire - IRSN (France)

    2014-07-01

    Effort over the last decade to make radioecology stronger and sustainable within Europe crystallized in the creation of the European Radioecology Alliance. The first step for this integrative effort was the establishment of a network of excellence (NoE) under the EU FP7 Strategy for Allied Radioecology (STAR www.star-radioecology.org) project which commenced in 2011. One of the project objectives was to share knowledge of European radioecological capabilities. To help achieve this, a register of these capabilities at each of the STAR laboratories has been created. An Infrastructure Database was designed and programmed using web 2.0 technologies on a 'wiki' platform. Its intended use was to identify what assets were held and where improvements could be made. Information collated includes an inventory of the radioanalytical or conventional equipment and methods, bio-informatics equipment and methods, sample and data archives held, and models and codes used. It also provides a summary of the radioecological expertise of the 170 radio-ecologists at STAR institutes whose knowledge is wide-ranging and encompasses: atmospheric dispersion, dosimetry, ecology, ecotoxicology, environmental radiation protection, environmental surveillance, foodstuffs, terrestrial, freshwater and marine radioecology, modelling, radiobiology and radionuclide analyses, emergency preparedness, education and training, amongst others. In 2013, the EU FP7 Coordination and implementation of a pan-European instrument for radioecology (COMET, www.comet-radioecology.org) project, involving the STAR partners and additionally one Japanese and two Ukrainian research institutes, was initiated. The capabilities of these additional partners will be added to the database in 2014. The aim of the database was to gather information to: - avoid duplication of effort and thereby increase efficiency, - improve synergy and collaboration between the STAR project partners and others involved in

  9. V and V Efforts of Auroral Precipitation Models: Preliminary Results

    Science.gov (United States)

    Zheng, Yihua; Kuznetsova, Masha; Rastaetter, Lutz; Hesse, Michael

    2011-01-01

    Auroral precipitation models have been valuable both in terms of space weather applications and space science research. Yet very limited testing has been performed regarding model performance. A variety of auroral models are available, including empirical models that are parameterized by geomagnetic indices or upstream solar wind conditions, now casting models that are based on satellite observations, or those derived from physics-based, coupled global models. In this presentation, we will show our preliminary results regarding V&V efforts of some of the models.

  10. Linking effort and fishing mortality in a mixed fisheries model

    DEFF Research Database (Denmark)

    Thøgersen, Thomas Talund; Hoff, Ayoe; Frost, Hans Staby

    2012-01-01

    in fish stocks has led to overcapacity in many fisheries, leading to incentives for overfishing. Recent research has shown that the allocation of effort among fleets can play an important role in mitigating overfishing when the targeting covers a range of species (multi-species—i.e., so-called mixed...... fisheries), while simultaneously optimising the overall economic performance of the fleets. The so-called FcubEcon model, in particular, has elucidated both the biologically and economically optimal method for allocating catches—and thus effort—between fishing fleets, while ensuring that the quotas...

  11. Efforts in Public Relations on Fusion in Europe

    Science.gov (United States)

    Ongena, J.; van Oost, G.

    2001-10-01

    An overview will be given of different published materials currently in use in Europe for public relations on fusion. We will also present a CD-ROM for individual and classroom use, containing (i) a general background on different energy forms, (ii) general principles of fusion, (iii) current research efforts and (iv) future prospects of fusion. This CD-ROM is currently in English, German, French, Spanish, Portuguese and Italian. Fusion posters developed in collaboration with CPEP in Dutch, French, German, Italian, Spanish and Portuguese will be shown. Several new brochures and leaflets intended to increase the public awareness on fusion in Europe will be on display.

  12. Kuwait poised for massive well kill effort

    Energy Technology Data Exchange (ETDEWEB)

    1991-04-08

    This paper reports that full scale efforts to extinguish Kuwait's oil well fires are to begin. The campaign to combat history's worst oil fires, originally expected to begin in mid-March, has been hamstrung by logistical problems, including delays in equipment deliveries caused by damage to Kuwait's infrastructure. Meantime, production from a key field off Kuwait--largely unaffected by the war--is expected to resume in May, but Kuwaiti oil exports will still be hindered by damaged onshore facilities. In addition, Kuwait is lining up equipment and personnel to restore production from its heavily damaged oil fields. Elsewhere in the Persian Gulf, Saudi Arabia reports progress in combating history's worst oil spills but acknowledges a continuing threat.

  13. Directed-energy process technology efforts

    Science.gov (United States)

    Alexander, P.

    1985-01-01

    A summary of directed-energy process technology for solar cells was presented. This technology is defined as directing energy or mass to specific areas on solar cells to produce a desired effect in contrast to exposing a cell to a thermal or mass flow environment. Some of these second generation processing techniques are: ion implantation; microwave-enhanced chemical vapor deposition; rapid thermal processing; and the use of lasers for cutting, assisting in metallization, assisting in deposition, and drive-in of liquid dopants. Advantages of directed energy techniques are: surface heating resulting in the bulk of the cell material being cooler and unchanged; better process control yields; better junction profiles, junction depths, and metal sintering; lower energy consumption during processing and smaller factory space requirements. These advantages should result in higher-efficiency cells at lower costs. The results of the numerous contracted efforts were presented as well as the application potentials of these new technologies.

  14. The European fusion nuclear technology effort

    International Nuclear Information System (INIS)

    Darvas, J.

    1989-01-01

    The role of fusion technology in the European fusion development strategy is outlined. The main thrust of the present fusion technology programme is responding to development needs of the Next European Torus. A smaller, but important and growing R and D effort is dealing with problems specific to the Demonstration, or Fusion Power, Reactor. The part of the programme falling under the somewhat arbitrarily defined category of 'fusion nuclear technology' is reviewed and an outlook to future activities is given. The review includes tritium technology, blanket technology and breeder materials development, technology and materials for the protection of the first wall and of other plasma facing components, remote handling technology, and safety and environmental impact studies. A few reflections are offered on the future long-term developments in fusion technology. (orig.)

  15. Peru continues to press privitization efforts

    International Nuclear Information System (INIS)

    Anon.

    1992-01-01

    This paper reports that Peru has again extended the deadline for bids on a 30 year operating contract for state owned Petromar SA's offshore Block Z-2b. The tender is key to efforts to privatize Petromar, a subsidiary of state oil company Petroleos del Peru. The committee charged with implementing Petromar privatization extended the deadline for bids another 70 days Oct. 30, following a 60 day extension made in September. The latest deadline for bids is Feb. 10, with the contract expected to be awarded Feb. 26. A bid package on Block Z-2b is available from Petroperu's Lima headquarters for $20,000. Petromar operates the former Belco Petroleum Corp. offshore assets Peru's government expropriated in 1985. It currently produces 17,600 b/d, compared with 27,000 b/d at the time of expropriation

  16. The present gravitational wave detection effort

    International Nuclear Information System (INIS)

    Riles, Keith

    2010-01-01

    Gravitational radiation offers a new non-electromagnetic window through which to observe the universe. The LIGO and Virgo Collaborations have completed a first joint data run with unprecedented sensitivities to gravitational waves. Results from searches in the data for a variety of astrophysical sources are presented. A second joint data run with improved detector sensitivities is underway, and soon major upgrades will be carried out to build Advanced LIGO and Advanced Virgo with expected improvements in event rates of more than 1000. In parallel there is a vigorous effort in the radio pulsar community to detect nHz gravitational waves via the timing residuals in an array of pulsars at different locations in the sky.

  17. Superconducting cavities developments efforts at RRCAT

    International Nuclear Information System (INIS)

    Puntambekar, A.; Bagre, M.; Dwivedi, J.; Shrivastava, P.; Mundra, G.; Joshi, S.C.; Potukuchi, P.N.

    2011-01-01

    Superconducting RE cavities are the work-horse for many existing and proposed linear accelerators. Raja Ramanna Centre for Advanced Technology (RRCAT) has initiated a comprehensive R and D program for development of Superconducting RF cavities suitable for high energy accelerator application like SNS and ADS. For the initial phase of technology demonstration several prototype 1.3 GHz single cell-cavities have been developed. The work began with development of prototype single cell cavities in aluminum and copper. This helped in development of cavity manufacturing process, proving various tooling and learning on various mechanical and RF qualification processes. The parts manufacturing was done at RRCAT and Electron beam welding was carried out at Indian industry. These cavities further served during commissioning trials for various cavity processing infrastructure being developed at RRCAT and are also a potential candidate for Niobium thin film deposition R and D. Based on the above experience, few single cell cavities were developed in fine grain niobium. The critical technology of forming and machining of niobium and the intermediate RF qualification were developed at RRCAT. The EB welding of bulk niobium cavities was carried out in collaboration with IUAC, New Delhi at their facility. As a next logical step efforts are now on for development of multicell cavities. The prototype dumbbells and end group made of aluminium, comprising of RF and HOM couplers ports have also been developed, with their LB welding done at Indian industry. In this paper we shall present the development efforts towards manufacturing of 1.3 GHz single cell cavities and their initial processing and qualification. (author)

  18. Research Reports

    Data.gov (United States)

    U.S. Department of Health & Human Services — The Centers for Medicare and Medicaid Services (CMS) research efforts span many topics, methods, and interests. Some projects address the Agencys immediate...

  19. Effortful semantic decision-making boosts memory performance in older adults

    OpenAIRE

    Fu, L.; Maes, J.H.R.; Varma, S.; Kessels, R.P.C.; Daselaar, S.M.

    2017-01-01

    A major concern in age-related cognitive decline is episodic memory (EM). Previous studies indicate that both resource and binding deficits contribute to EM decline. Environmental support by task manipulations encouraging stronger cognitive effort and deeper levels of processing may facilitate compensation for these two deficits. To clarify factors that can counteract age-related EM decline, we assessed effects of cognitive effort (four levels) and level of processing (LoP, shallow/deep) duri...

  20. Effort, anhedonia, and function in schizophrenia: reduced effort allocation predicts amotivation and functional impairment.

    Science.gov (United States)

    Barch, Deanna M; Treadway, Michael T; Schoen, Nathan

    2014-05-01

    One of the most debilitating aspects of schizophrenia is an apparent interest in or ability to exert effort for rewards. Such "negative symptoms" may prevent individuals from obtaining potentially beneficial outcomes in educational, occupational, or social domains. In animal models, dopamine abnormalities decrease willingness to work for rewards, implicating dopamine (DA) function as a candidate substrate for negative symptoms given that schizophrenia involves dysregulation of the dopamine system. We used the effort-expenditure for rewards task (EEfRT) to assess the degree to which individuals with schizophrenia were wiling to exert increased effort for either larger magnitude rewards or for rewards that were more probable. Fifty-nine individuals with schizophrenia and 39 demographically similar controls performed the EEfRT task, which involves making choices between "easy" and "hard" tasks to earn potential rewards. Individuals with schizophrenia showed less of an increase in effort allocation as either reward magnitude or probability increased. In controls, the frequency of choosing the hard task in high reward magnitude and probability conditions was negatively correlated with depression severity and anhedonia. In schizophrenia, fewer hard task choices were associated with more severe negative symptoms and worse community and work function as assessed by a caretaker. Consistent with patterns of disrupted dopamine functioning observed in animal models of schizophrenia, these results suggest that 1 mechanism contributing to impaired function and motivational drive in schizophrenia may be a reduced allocation of greater effort for higher magnitude or higher probability rewards.

  1. The Kavirondo Escarpment: a previously unrecognized site of high ...

    African Journals Online (AJOL)

    Despite only a limited effort there, we report several new atlas square occurrences, presence of the local and poorly known Rock Cisticola Cisticola emini and a significant range extension for the Stone Partridge Ptilopachus petrosus. Our short visits indicate high avian species richness is associated with the escarpment and ...

  2. Mindfulness training affects attention—Or is it attentional effort?

    DEFF Research Database (Denmark)

    Jensen, Christian Gaden; Vangkilde, Signe Allerup; Frøkjær, Vibe Gedsø

    2012-01-01

    Improvements in attentional performance are at the core of proposed mechanisms for stress reduction in mindfulness meditation practices. However, this claim can be questioned because no previous studies have actively manipulated test effort in control groups and controlled for effects of stress...... reduction per se. In a blinded design, 48 young, healthy meditation novices were randomly assigned to a mindfulness-based stress reduction (MBSR), nonmindfulness stress reduction (NMSR), or inactive control group. At posttest, inactive controls were randomly split into nonincentive and incentive controls......, the latter receiving a financial reward to improve attentional performance. Pre- and postintervention, 5 validated attention paradigms were employed along with self-report scales on mindfulness and perceived stress and saliva cortisol samples to measure physiological stress. Attentional effects of MBSR, NMSR...

  3. Maintenance personnel performance simulation (MAPPS) model: overview and evaluation efforts

    International Nuclear Information System (INIS)

    Knee, H.E.; Haas, P.M.; Siegel, A.I.; Bartter, W.D.; Wolf, J.J.; Ryan, T.G.

    1984-01-01

    The development of the MAPPS model has been completed and the model is currently undergoing evaluation. These efforts are addressing a number of identified issues concerning practicality, acceptability, usefulness, and validity. Preliminary analysis of the evaluation data that has been collected indicates that MAPPS will provide comprehensive and reliable data for PRA purposes and for a number of other applications. The MAPPS computer simulation model provides the user with a sophisticated tool for gaining insights into tasks performed by NPP maintenance personnel. Its wide variety of input parameters and output data makes it extremely flexible for application to a number of diverse applications. With the demonstration of favorable model evaluation results, the MAPPS model will represent a valuable source of NPP maintainer reliability data and provide PRA studies with a source of data on maintainers that has previously not existed

  4. Military efforts in nanosensors, 3D printing, and imaging detection

    Science.gov (United States)

    Edwards, Eugene; Booth, Janice C.; Roberts, J. Keith; Brantley, Christina L.; Crutcher, Sihon H.; Whitley, Michael; Kranz, Michael; Seif, Mohamed; Ruffin, Paul

    2017-04-01

    A team of researchers and support organizations, affiliated with the Army Aviation and Missile Research, Development, and Engineering Center (AMRDEC), has initiated multidiscipline efforts to develop nano-based structures and components for advanced weaponry, aviation, and autonomous air/ground systems applications. The main objective of this research is to exploit unique phenomena for the development of novel technology to enhance warfighter capabilities and produce precision weaponry. The key technology areas that the authors are exploring include nano-based sensors, analysis of 3D printing constituents, and nano-based components for imaging detection. By integrating nano-based devices, structures, and materials into weaponry, the Army can revolutionize existing (and future) weaponry systems by significantly reducing the size, weight, and cost. The major research thrust areas include the development of carbon nanotube sensors to detect rocket motor off-gassing; the application of current methodologies to assess materials used for 3D printing; and the assessment of components to improve imaging seekers. The status of current activities, associated with these key areas and their implementation into AMRDEC's research, is outlined in this paper. Section #2 outlines output data, graphs, and overall evaluations of carbon nanotube sensors placed on a 16 element chip and exposed to various environmental conditions. Section #3 summarizes the experimental results of testing various materials and resulting components that are supplementary to additive manufacturing/fused deposition modeling (FDM). Section #4 recapitulates a preliminary assessment of the optical and electromechanical components of seekers in an effort to propose components and materials that can work more effectively.

  5. Safety and immunogenicity of 2010-2011 H1N12009-containing trivalent inactivated influenza vaccine in children 12-59 months of age previously given AS03-adjuvanted H1N12009 pandemic vaccine: a PHAC/CIHR Influenza Research Network (PCIRN) study.

    Science.gov (United States)

    Langley, Joanne M; Scheifele, David W; Quach, Caroline; Vanderkooi, Otto G; Ward, Brian; McNeil, Shelly; Dobson, Simon; Kellner, James D; Kuhn, Susan; Kollman, Tobias; MacKinnon-Cameron, Donna; Smith, Bruce; Li, Yan; Halperin, Scott A

    2012-05-14

    Concern arose in 2010 that reactogenicity, particularly febrile seizures, to influenza A/H1N1-containing 2010-2011 trivalent seasonal inactivated influenza vaccine (TIV) could occur in young children who had been previously immunized and/or infected with the pandemic strain. We conducted a pre-season study of 2010-2011 TIV safety and immunogenicity in children 12-59 months of age to inform public health decision making. Children immunized with 1 or 2 doses of the pandemic vaccine, with or without the 2009-10 TIV, received 1 or 2 doses of 2010-11 TIV in an observational, multicentre Canadian study. Standard safety monitoring was enhanced by a telephone call at ~24 h post-TIV when adverse events were expected to peak. Summary safety reports were rapidly reported to public health before the launch of public programs. TIV immunogenicity was assessed day 0, and 21 days after final vaccination. Clinical Trials Registration NCT01180621. Among 207 children, a general adverse event was reported by 60.9% of children post-dose one and by 58.3% post-dose two. Only severe fever (>38.5°C) was more common in two-dose compared to one dose recipients (16.7%, n=4 v. 1.0%, n=2). At baseline 99.0% of participants had A/H1N1 hemagglutinin inhibition (HAI) titers ≥10, and 85.5% had a protective titer of ≥40 (95% CI 80.0, 90.0). Baseline geometric mean titers (GMT) were higher in recipients of a 2-dose schedule of pandemic vaccine compared to one-dose recipients: 153.1 (95% CI 126.2, 185.7) v. 78.8 ((58.1, 106.8, pvaccine immunogenicity were exceeded for A/H1N1 and H3N2, but responses to the B antigen were poor. No correlations between reactogenicity and either baseline high influenza titers or serologic response to revaccination were evident. Infants and toddlers who received AS03-adjuvanted A/H1N1 2009 vaccine up to 11 months earlier retained high titers in the subsequent season but re-exposure to A/H1N1 2009 antigen in TIV resulted in no unusual adverse effects and 100% were sero

  6. 49 CFR 173.23 - Previously authorized packaging.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 2 2010-10-01 2010-10-01 false Previously authorized packaging. 173.23 Section... REQUIREMENTS FOR SHIPMENTS AND PACKAGINGS Preparation of Hazardous Materials for Transportation § 173.23 Previously authorized packaging. (a) When the regulations specify a packaging with a specification marking...

  7. 28 CFR 10.5 - Incorporation of papers previously filed.

    Science.gov (United States)

    2010-07-01

    ... 28 Judicial Administration 1 2010-07-01 2010-07-01 false Incorporation of papers previously filed... CARRYING ON ACTIVITIES WITHIN THE UNITED STATES Registration Statement § 10.5 Incorporation of papers previously filed. Papers and documents already filed with the Attorney General pursuant to the said act and...

  8. 75 FR 76056 - FEDERAL REGISTER CITATION OF PREVIOUS ANNOUNCEMENT:

    Science.gov (United States)

    2010-12-07

    ... SECURITIES AND EXCHANGE COMMISSION Sunshine Act Meeting FEDERAL REGISTER CITATION OF PREVIOUS ANNOUNCEMENT: STATUS: Closed meeting. PLACE: 100 F Street, NE., Washington, DC. DATE AND TIME OF PREVIOUSLY ANNOUNCED MEETING: Thursday, December 9, 2010 at 2 p.m. CHANGE IN THE MEETING: Time change. The closed...

  9. International Collaboration Enhances Cancer Screening Efforts

    Science.gov (United States)

    CGH is working with the International Agency for Research on CancerExit Disclaimer (IARC) and the Pan American Health Organization (PAHO) on the ESTAMPA Study, a multi-centric study of cervical cancer screening and triage with HPV testing.

  10. No discrimination against previous mates in a sexually cannibalistic spider

    Science.gov (United States)

    Fromhage, Lutz; Schneider, Jutta M.

    2005-09-01

    In several animal species, females discriminate against previous mates in subsequent mating decisions, increasing the potential for multiple paternity. In spiders, female choice may take the form of selective sexual cannibalism, which has been shown to bias paternity in favor of particular males. If cannibalistic attacks function to restrict a male's paternity, females may have little interest to remate with males having survived such an attack. We therefore studied the possibility of female discrimination against previous mates in sexually cannibalistic Argiope bruennichi, where females almost always attack their mate at the onset of copulation. We compared mating latency and copulation duration of males having experienced a previous copulation either with the same or with a different female, but found no evidence for discrimination against previous mates. However, males copulated significantly shorter when inserting into a used, compared to a previously unused, genital pore of the female.

  11. Implant breast reconstruction after salvage mastectomy in previously irradiated patients.

    Science.gov (United States)

    Persichetti, Paolo; Cagli, Barbara; Simone, Pierfranco; Cogliandro, Annalisa; Fortunato, Lucio; Altomare, Vittorio; Trodella, Lucio

    2009-04-01

    The most common surgical approach in case of local tumor recurrence after quadrantectomy and radiotherapy is salvage mastectomy. Breast reconstruction is the subsequent phase of the treatment and the plastic surgeon has to operate on previously irradiated and manipulated tissues. The medical literature highlights that breast reconstruction with tissue expanders is not a pursuable option, considering previous radiotherapy a contraindication. The purpose of this retrospective study is to evaluate the influence of previous radiotherapy on 2-stage breast reconstruction (tissue expander/implant). Only patients with analogous timing of radiation therapy and the same demolitive and reconstructive procedures were recruited. The results of this study prove that, after salvage mastectomy in previously irradiated patients, implant reconstruction is still possible. Further comparative studies are, of course, advisable to draw any conclusion on the possibility to perform implant reconstruction in previously irradiated patients.

  12. Efek Keadilan Remunerasi, Kompetensi Atasan dan Kohesivitas Kelompok terhadap Withholding Effort

    Directory of Open Access Journals (Sweden)

    Ida Ayu Kartika Maharani

    2016-12-01

    Full Text Available Withholding effort is a tendency employee to reduce work contribution as the possibility of an individual in giving less than maximum effort on tasks associated with the job. The purpose of this study is to analyze the remuneration fairness influences, supervisor competencies and group cohesiveness on withholding effort. The population in this study was all administrative employees with the status of civil servants and probationary civil servants who were actively working in the Institute Hindu Dharma Negeri Denpasar. The number of respondents were 80 people. The research data was primary data obtained from questionnaires. This study used confirmatory factor analysis and multiple linear regression analysis as analytic technique. The results show that fairness of remuneration has a negative and significant effect on the withholding effort, supervisor competencies has a negative and significant effect on the withholding effort, group cohesiveness  has a negative and significant effect on the withholding effort

  13. Effect of social influence on effort-allocation for monetary rewards.

    Science.gov (United States)

    Gilman, Jodi M; Treadway, Michael T; Curran, Max T; Calderon, Vanessa; Evins, A Eden

    2015-01-01

    Though decades of research have shown that people are highly influenced by peers, few studies have directly assessed how the value of social conformity is weighed against other types of costs and benefits. Using an effort-based decision-making paradigm with a novel social influence manipulation, we measured how social influence affected individuals' decisions to allocate effort for monetary rewards during trials with either high or low probability of receiving a reward. We found that information about the effort-allocation of peers modulated participant choices, specifically during conditions of low probability of obtaining a reward. This suggests that peer influence affects effort-based choices to obtain rewards especially under conditions of risk. This study provides evidence that people value social conformity in addition to other costs and benefits when allocating effort, and suggests that neuroeconomic studies that assess trade-offs between effort and reward should consider social environment as a factor that can influence decision-making.

  14. Left ventricular asynergy score as an indicator of previous myocardial infarction

    International Nuclear Information System (INIS)

    Backman, C.; Jacobsson, K.A.; Linderholm, H.; Osterman, G.

    1986-01-01

    Sixty-eight patients with coronary heart disease (CHD) i.e. a hisotry of angina of effort and/or previous 'possible infarction' were examined inter alia with ECG and cinecardioangiography. A system of scoring was designed which allowed a semiquantitative estimate of the left ventricular asynergy from cinecardioangiography - the left ventricular motion score (LVMS). The LVMS was associated with the presence of a previous myocardial infarction (MI), as indicated by the history and ECG findings. The ECG changes specific for a previous MI were associated with high LVMS values and unspecific or absent ECG changes with low LVMS values. Decision thresholds for ECG changes and asynergy in diagnosing a previous MI were evaluated by means of a ROC analysis. The accuracy of ECG in detecting a previous MI was slightly higher when asynergy indicated a 'true MI' than when autopsy result did so in a comparable group. Therefore the accuracy of asynergy (LVMS ≥ 1) in detecting a previous MI or myocardial fibrosis in patients with CHD should be at least comparable with that of autopsy (scar > 1 cm). (orig.)

  15. Molecular biologists backing effort to map entire human genome

    International Nuclear Information System (INIS)

    Zurer, P.S.

    1988-01-01

    This article discusses how the program to map and sequence the human genome will be managed. The National Research Council (NRC) recommends that a 15-year $200-million-a-year effort to map all human genes should begin immediately. However, some people have balked at the idea, saying it is a ploy to raise money. Part of the skeptic's uneasiness stems from the involvement of the Department of Energy (DOE), an agency not often linked with biological research. The DOE's interest arises from its commitment to understanding the biological effects of nuclear radiation. Critics say it is a budget-boosting tactic. This article explains some of the arguments for and against the project and explains exactly what it would involve

  16. Slow growth efforts renewed in Iran.

    Science.gov (United States)

    Aghajanian, A

    1992-10-01

    Iran's first population policy was developed under the Shah in 1967. Policymakers brought in with the Islamic Revolution of 1979, however, rejected much of the earlier regime's views on women and childbearing. During the Iran-Iraq war of 1980-88, large population size and rapid growth were seen as advantageous to the war effort. After the war, the government of Iran again began to voice concern about rapid population growth. The pragmatic and proactive approach taken by the government since 1988 may, indeed, accelerate a decline in fertility began in the late 1960s, but stalled in the 1980s. The following are examples of the new governmental attitude: the Iranian government announced March 1992 that it would begin importing Norplant and make it available along with other contraceptives at public clinics; last year, the government announced that the fourth child of a family would not be eligible for food rationing or nutritional supplements and other public child benefits; the Minister of Health in 1991 for the first time publicly encouraged male sterilization; and last fall, Iran conducted a special census of the population five years before the regular decennial census date of 1996. These actions represent dramatic policy changes on population growth and family planning in this country of 60 million, the largest and one of the fastest growing in the Middle East.

  17. ICRP new recommendations. Committee 2's efforts

    International Nuclear Information System (INIS)

    Eckerman, K.F.

    2007-01-01

    The International Commission on Radiological Protection (ICRP) may release new primary radiation protection recommendation in 2007. Committee 2 has underway reviews of the dosimetric and biokinetic models and associated data used in calculating dose coefficients for intakes of radionuclides and exposures to external radiation fields. This paper outlines the work plans of Committee 2 during the current term, 2005-2009, in anticipation of the new primary recommendations. The two task groups of Committee 2 responsible for the computations of dose coefficients, INDOS and DOCAL, are reviewing the models and data used in the computations. INDOS is reviewing the lung model and the biokinetic models that describe the behavior of the radionuclides in the body. DOCAL is reviewing its computational formulations with the objective of harmonizing the formulation with those of nuclear medicine, and developing new computational phantoms representing the adult male and female reference individuals of ICRP Publication 89. In addition, DOCAL will issue a publication on nuclear decay data to replace ICRP Publication 38. While the current efforts are focused on updating the dose coefficients for occupational intakes of radionuclides plans are being formulated to address dose coefficients for external radiation fields which include consideration of high energy fields associated with accelerators and space travel and the updating of dose coefficients for members of the public. (author)

  18. STEM Education Efforts in the Ares Projects

    Science.gov (United States)

    Doreswamy, Rajiv; Armstrong, Robert C.

    2010-01-01

    According to the National Science Foundation, of the more than 4 million first university degrees awarded in science and engineering in 2006, students in China earned about 21%, those in the European Union earned about 19%, and those in the United States earned about 11%. Statistics like these are of great interest to NASA's Ares Projects, which are responsible for building the rockets for the U.S. Constellation Program to send humans beyond low-Earth orbit. Science, technology, engineering, and mathematics students are essential for the long-term sustainability of any space program. Since the Projects creation, the Ares Outreach Team has used a variety of STEM-related media, methods, and materials to engage students, educators, and the general public in Constellation's mission. Like Project Apollo, the nation s exploration destinations and the vehicles used to get there can inspire students to learn more about STEM. Ares has been particularly active in public outreach to schools in Northern Alabama; on the Internet via outreach and grade-specific educational materials; and in more informal social media settings such as YouTube and Facebook. These combined efforts remain integral to America s space program, regardless of its future direction.

  19. 1991 research and technology

    Science.gov (United States)

    1992-01-01

    Selected research and technology activities at Ames Research Center, including the Moffett Field site and the Dryden Flight Research Facility, are summarized. These activities exemplify the Center's varied and productive research efforts for 1991.

  20. Quality-oriented efforts in IPD, - a framework

    DEFF Research Database (Denmark)

    Andreasen, Mogens Myrup

    1998-01-01

    It is generally expected that modern quality efforts like TQM and ISO9000 should deliver a sufficient framework for quality efforts in industrial companies. Our findings in Danish industry shows a fragmented picture of islands of efforts and a weak understanding of basic quality concepts between...... designers. The paper propose a framework for quality efforts, illustrated by simple metaphors....

  1. Personality disorders in previously detained adolescent females: a prospective study

    NARCIS (Netherlands)

    Krabbendam, A.; Colins, O.F.; Doreleijers, T.A.H.; van der Molen, E.; Beekman, A.T.F.; Vermeiren, R.R.J.M.

    2015-01-01

    This longitudinal study investigated the predictive value of trauma and mental health problems for the development of antisocial personality disorder (ASPD) and borderline personality disorder (BPD) in previously detained women. The participants were 229 detained adolescent females who were assessed

  2. Payload specialist Reinhard Furrer show evidence of previous blood sampling

    Science.gov (United States)

    1985-01-01

    Payload specialist Reinhard Furrer shows evidence of previous blood sampling while Wubbo J. Ockels, Dutch payload specialist (only partially visible), extends his right arm after a sample has been taken. Both men show bruises on their arms.

  3. Choice of contraception after previous operative delivery at a family ...

    African Journals Online (AJOL)

    Choice of contraception after previous operative delivery at a family planning clinic in Northern Nigeria. Amina Mohammed‑Durosinlorun, Joel Adze, Stephen Bature, Caleb Mohammed, Matthew Taingson, Amina Abubakar, Austin Ojabo, Lydia Airede ...

  4. Previous utilization of service does not improve timely booking in ...

    African Journals Online (AJOL)

    Previous utilization of service does not improve timely booking in antenatal care: Cross sectional study ... Journal Home > Vol 24, No 3 (2010) > ... Results: Past experience on antenatal care service utilization did not come out as a predictor for ...

  5. Quality management: efforts and problems in Ethiopian ...

    African Journals Online (AJOL)

    This paper deals with the analysis and the current quality management practices in Ethiopian manufacturing industries. The research is based on a survey conducted on 55 representative industries all over the country. A brief introduction is given on the fundamental concepts of quality with reference to the recent literature ...

  6. A previous hamstring injury affects kicking mechanics in soccer players.

    Science.gov (United States)

    Navandar, Archit; Veiga, Santiago; Torres, Gonzalo; Chorro, David; Navarro, Enrique

    2018-01-10

    Although the kicking skill is influenced by limb dominance and sex, how a previous hamstring injury affects kicking has not been studied in detail. Thus, the objective of this study was to evaluate the effect of sex and limb dominance on kicking in limbs with and without a previous hamstring injury. 45 professional players (males: n=19, previously injured players=4, age=21.16 ± 2.00 years; females: n=19, previously injured players=10, age=22.15 ± 4.50 years) performed 5 kicks each with their preferred and non-preferred limb at a target 7m away, which were recorded with a three-dimensional motion capture system. Kinematic and kinetic variables were extracted for the backswing, leg cocking, leg acceleration and follow through phases. A shorter backswing (20.20 ± 3.49% vs 25.64 ± 4.57%), and differences in knee flexion angle (58 ± 10o vs 72 ± 14o) and hip flexion velocity (8 ± 0rad/s vs 10 ± 2rad/s) were observed in previously injured, non-preferred limb kicks for females. A lower peak hip linear velocity (3.50 ± 0.84m/s vs 4.10 ± 0.45m/s) was observed in previously injured, preferred limb kicks of females. These differences occurred in the backswing and leg-cocking phases where the hamstring muscles were the most active. A variation in the functioning of the hamstring muscles and that of the gluteus maximus and iliopsoas in the case of a previous injury could account for the differences observed in the kicking pattern. Therefore, the effects of a previous hamstring injury must be considered while designing rehabilitation programs to re-educate kicking movement.

  7. The value of the wechsler intelligence scale for children-fourth edition digit span as an embedded measure of effort: an investigation into children with dual diagnoses.

    Science.gov (United States)

    Loughan, Ashlee R; Perna, Robert; Hertza, Jeremy

    2012-11-01

    The Test of Memory Malingering (TOMM) is a measure of test-taking effort which has traditionally been utilized with adults, but which more recently has demonstrated utility with children. The purpose of this study was to investigate whether the Wechsler Intelligence Scale for Children-Fourth Edition (WISC-IV) Digit Span, commonly used in neuropsychological evaluations, can also be functional as an embedded measure by detecting effort in children with dual diagnoses; a population yet to be investigated. Participants (n = 51) who completed neuropsychological evaluations including the TOMM, WISC-IV, Wisconsin Card Sorting Test, Children's Memory Scale, and Delis-Kaplan Executive Function System were divided into two groups: Optimal Effort and Suboptimal Effort, based on their TOMM Trial 2 scores. Digit Span findings suggest a useful scaled score of ≤4 resulted in optimal cutoff scores, yielding specificity of 91% and sensitivity of 43%. This study supports previous research that the WISC-IV Digit Span has good utility in determining optimal effort, even in children with dual diagnosis or comorbidities.

  8. Do Effort and Reward at Work Predict Changes in Cognitive Function? First Longitudinal Results from the Representative German Socio-Economic Panel.

    Science.gov (United States)

    Riedel, Natalie; Siegrist, Johannes; Wege, Natalia; Loerbroks, Adrian; Angerer, Peter; Li, Jian

    2017-11-15

    It has been suggested that work characteristics, such as mental demands, job control, and occupational complexity, are prospectively related to cognitive function. However, current evidence on links between psychosocial working conditions and cognitive change over time is inconsistent. In this study, we applied the effort-reward imbalance model that allows to build on previous research on mental demands and to introduce reward-based learning as a principle with beneficial effect on cognitive function. We aimed to investigate whether high effort, high reward, and low over-commitment in 2006 were associated with positive changes in cognitive function in terms of perceptual speed and word fluency (2006-2012), and whether the co-manifestation of high effort and high reward would yield the strongest association. To this end, we used data on 1031 employees who participated in a large and representative study. Multivariate linear regression analyses supported our main hypotheses (separate and combined effects of effort and reward), particularly on changes in perceptual speed, whereas the effects of over-commitment did not reach the level of statistical significance. Our findings extend available knowledge by examining the course of cognitive function over time. If corroborated by further evidence, organization-based measures in the workplace can enrich efforts towards preventing cognitive decline in ageing workforces.

  9. 1996 Design effort for IFMIF HEBT

    International Nuclear Information System (INIS)

    Blind, B.

    1997-01-01

    The paper details the 1996 design effort for the IFMIF HEBT. Following a brief overview, it lists the primary requirements for the beam at the target, describes the design approach and design tools used, introduces the beamline modules, gives the results achieved with the design at this stage, points out possible improvements and gives the names and computer locations of the TRACE3-D and PARMILA files that sum up the design work. The design does not fully meet specifications in regards to the flatness of the distribution at the target. With further work, including if necessary some backup options, the flatness specifications may be realized. It is not proposed that the specifications, namely flatness to ±5% and higher-intensity ridges that are no more than 15% above average, be changed at this time. The design also does not meet the requirement that the modules of all beamlines should operate at the same settings. However, the goal of using identical components and operational procedures has been met and only minor returning is needed to produce very similar beam distributions from all beamlines. Significant further work is required in the following areas: TRACE3-D designs and PARMILA runs must be made for the beams coming from accelerators No. 3 and No. 4. Transport of 30-MeV and 35-MeV beams to the targets and beam dump must be studied. Comprehensive error studies must be made. These must result in tolerance specifications and may require design iterations. Detailed interfacing with target-spot instrumentation is required. This instrumentation must be able to check all aspects of the specifications

  10. Manager's effort and endogenous economic discrimination

    Directory of Open Access Journals (Sweden)

    Jaime Orrillo

    2004-09-01

    Full Text Available Assume a labor supply consisting of two types of workers, 1 and 2. Both workers are equally productive and exhibit supply functions with the same elasticity. We consider a firm (entrepreneur or shareholders that is competitive in the output market and monopsonistic in input markets. The firm uses the services of a manager who has a high human capital and whose wage is given by the market. It is supposed that the manager does not like to work with one type of worker, say type 1. If we allow the manager's effort to be an additional input without any extra (in addition to his salary cost for the firm, then the firm's pricing decision will be different for both workers. That is, there will be a wage differential and therefore endogenous economic discrimination2 in the labor markets.Vamos assumir que a oferta de trabalho consiste de dois tipos de trabalhadores, 1 e 2. Ambos os trabalhadores são igualmente produtivos e exibem funções de oferta com a mesma elasticidade. Consideramos uma firma (empresário ou acionistas, a qual é competitiva no mercado de produtos e monopsonista nos mercados de insumos. A firma usa os serviços de um gerente quem tem um alto capital humano e cujo salário é dado pelo mercado. Suponhamos que o gerente não gosta de trabalhar com um tipo de trabalhador, digamos o tipo 1. Se permitirmos que o esforço do gerente seja um insumo adicional sem nenhum custo extra (além de seu salário, a decisão de salários será diferente para ambos os trabalhadores. Isto é, haverá um diferencial de salários e, em conseqüência, uma discriminação econômica1 endógena nos mercados de trabalho.

  11. Complementary roles of different oscillatory activities in the subthalamic nucleus in coding motor effort in Parkinsonism.

    Science.gov (United States)

    Tan, Huiling; Pogosyan, Alek; Anzak, Anam; Ashkan, Keyoumars; Bogdanovic, Marko; Green, Alexander L; Aziz, Tipu; Foltynie, Thomas; Limousin, Patricia; Zrinzo, Ludvic; Brown, Peter

    2013-10-01

    The basal ganglia may play an important role in the control of motor scaling or effort. Recently local field potential (LFP) recordings from patients with deep brain stimulation electrodes in the basal ganglia have suggested that local increases in the synchronisation of neurons in the gamma frequency band may correlate with force or effort. Whether this feature uniquely codes for effort and whether such a coding mechanism holds true over a range of efforts is unclear. Here we investigated the relationship between frequency-specific oscillatory activities in the subthalamic nucleus (STN) and manual grips made with different efforts. The latter were self-rated using the 10 level Borg scale ranging from 0 (no effort) to 10 (maximal effort). STN LFP activities were recorded in patients with Parkinson's Disease (PD) who had undergone functional surgery. Patients were studied while motor performance was improved by dopaminergic medication. In line with previous studies we observed power increase in the theta/alpha band (4-12 Hz), power suppression in the beta band (13-30 Hz) and power increase in the gamma band (55-90 Hz) and high frequency band (101-375 Hz) during voluntary grips. Beta suppression deepened, and then reached a floor level as effort increased. Conversely, gamma and high frequency power increases were enhanced during grips made with greater effort. Multiple regression models incorporating the four different spectral changes confirmed that the modulation of power in the beta band was the only independent predictor of effort during grips made with efforts rated <5. In contrast, increases in gamma band activity were the only independent predictor of effort during grips made with efforts ≥5. Accordingly, the difference between power changes in the gamma and beta bands correlated with effort across all effort levels. These findings suggest complementary roles for changes in beta and gamma band activities in the STN in motor effort coding. The latter function

  12. Task difficulty, risk, effort and comfort in a simulated driving task--Implications for Risk Allostasis Theory.

    Science.gov (United States)

    Lewis-Evans, Ben; Rothengatter, Talib

    2009-09-01

    Risk Allostasis Theory states that drivers seek to maintain a feeling of risk within a preferred range [Fuller, R., 2008. What drives the driver? Surface tensions and hidden consensus. In: Keynote at the 4th International Conference on Traffic and Transport Psychology, Washington, DC, August 31-September 4, 2008]. Risk Allostasis Theory is the latest version of Task-Difficulty Homeostasis theory, and is in part based on the findings of experiments where participants were asked to rate the task difficulty, feeling of risk and chance of collision of scenes shown in digitally altered video clips [Fuller, R., McHugh, C., Pender, S., 2008b. Task difficulty and risk in the determination of driver behaviour. Revue européenne de psychologie appliqée 58, 13-21]. The focus of the current research was to expand upon the previous video based experiments using a driving simulator. This allowed participants to be in control of the vehicle rather than acting as passive observers, as well as providing additional speed cues. The results support previous findings that ratings of task difficulty and feeling of risk are related, and that they are also highly related to ratings of effort and moderately related to ratings of comfort and habit. However, the linearly increasing trend for task difficulty and feeling of risk described by the previous research was not observed: instead the findings of this experiment support a threshold effect where ratings of risk (feeling of and chance of loss of control/collision), difficulty, effort, and comfort go through a period of stability and only start to increase once a certain threshold has been crossed. It is within the period of stability where subjective experience of risk and difficulty is low, or absent, that drivers generally prefer to operate.

  13. Comparison of cardiovascular response to combined static-dynamic effort, postprandial dynamic effort and dynamic effort alone in patients with chronic ischemic heart disease

    International Nuclear Information System (INIS)

    Hung, J.; McKillip, J.; Savin, W.; Magder, S.; Kraus, R.; Houston, N.; Goris, M.; Haskell, W.; DeBusk, R.

    1982-01-01

    The cardiovascular responses to combined static-dynamic effort, postprandial dynamic effort and dynamic effort alone were evaluated by upright bicycle ergometry during equilibrium-gated blood pool scintigraphy in 24 men, mean age 59 +/- 8 years, with chronic ischemic heart disease. Combined static-dynamic effort and the postprandial state elicited a peak cardiovascular response similar to that of dynamic effort alone. Heart rate, intraarterial systolic and diastolic pressures, rate-pressure product and ejection fraction were similar for the three test conditions at the onset of ischemia and at peak effort. The prevalence and extent of exercise-induced ischemic left ventricular dysfunction, ST-segment depression, angina pectoris and ventricular ectopic activity were also similar during the three test conditions. Direct and indirect measurements of systolic and diastolic blood pressure were highly correlated. The onset of ischemic ST-segment depression and angina pectoris correlated as strongly with heart rate alone as with the rate-pressure product during all three test conditions. The cardiovascular response to combined static-dynamic effort and to postprandial dynamic effort becomes more similar to that of dynamic effort alone as dynamic effort reaches a symptom limit. If significant ischemic and arrhythmic abnormalities are absent during symptom-limited dynamic exercise testing, they are unlikely to appear during combined static-dynamic or postprandial dynamic effort

  14. The Assessment of Muscular Effort, Fatigue, and Physiological Adaptation Using EMG and Wavelet Analysis.

    Science.gov (United States)

    Graham, Ryan B; Wachowiak, Mark P; Gurd, Brendon J

    2015-01-01

    Peroxisome proliferator-activated receptor gamma coactivator 1 alpha (PGC-1α) is a transcription factor co-activator that helps coordinate mitochondrial biogenesis within skeletal muscle following exercise. While evidence gleaned from submaximal exercise suggests that intracellular pathways associated with the activation of PGC-1α, as well as the expression of PGC-1α itself are activated to a greater extent following higher intensities of exercise, we have recently shown that this effect does not extend to supramaximal exercise, despite corresponding increases in muscle activation amplitude measured with electromyography (EMG). Spectral analyses of EMG data may provide a more in-depth assessment of changes in muscle electrophysiology occurring across different exercise intensities, and therefore the goal of the present study was to apply continuous wavelet transforms (CWTs) to our previous data to comprehensively evaluate: 1) differences in muscle electrophysiological properties at different exercise intensities (i.e. 73%, 100%, and 133% of peak aerobic power), and 2) muscular effort and fatigue across a single interval of exercise at each intensity, in an attempt to shed mechanistic insight into our previous observations that the increase in PGC-1α is dissociated from exercise intensity following supramaximal exercise. In general, the CWTs revealed that localized muscle fatigue was only greater than the 73% condition in the 133% exercise intensity condition, which directly matched the work rate results. Specifically, there were greater drop-offs in frequency, larger changes in burst power, as well as greater changes in burst area under this intensity, which were already observable during the first interval. As a whole, the results from the present study suggest that supramaximal exercise causes extreme localized muscular fatigue, and it is possible that the blunted PGC-1α effects observed in our previous study are the result of fatigue-associated increases in

  15. The Assessment of Muscular Effort, Fatigue, and Physiological Adaptation Using EMG and Wavelet Analysis.

    Directory of Open Access Journals (Sweden)

    Ryan B Graham

    Full Text Available Peroxisome proliferator-activated receptor gamma coactivator 1 alpha (PGC-1α is a transcription factor co-activator that helps coordinate mitochondrial biogenesis within skeletal muscle following exercise. While evidence gleaned from submaximal exercise suggests that intracellular pathways associated with the activation of PGC-1α, as well as the expression of PGC-1α itself are activated to a greater extent following higher intensities of exercise, we have recently shown that this effect does not extend to supramaximal exercise, despite corresponding increases in muscle activation amplitude measured with electromyography (EMG. Spectral analyses of EMG data may provide a more in-depth assessment of changes in muscle electrophysiology occurring across different exercise intensities, and therefore the goal of the present study was to apply continuous wavelet transforms (CWTs to our previous data to comprehensively evaluate: 1 differences in muscle electrophysiological properties at different exercise intensities (i.e. 73%, 100%, and 133% of peak aerobic power, and 2 muscular effort and fatigue across a single interval of exercise at each intensity, in an attempt to shed mechanistic insight into our previous observations that the increase in PGC-1α is dissociated from exercise intensity following supramaximal exercise. In general, the CWTs revealed that localized muscle fatigue was only greater than the 73% condition in the 133% exercise intensity condition, which directly matched the work rate results. Specifically, there were greater drop-offs in frequency, larger changes in burst power, as well as greater changes in burst area under this intensity, which were already observable during the first interval. As a whole, the results from the present study suggest that supramaximal exercise causes extreme localized muscular fatigue, and it is possible that the blunted PGC-1α effects observed in our previous study are the result of fatigue

  16. Standardization efforts of digital pathology in Europe.

    Science.gov (United States)

    Rojo, Marcial García; Daniel, Christel; Schrader, Thomas

    2012-01-01

    EURO-TELEPATH is a European COST Action IC0604. It started in 2007 and will end in November 2011. Its main objectives are evaluating and validating the common technological framework and communication standards required to access, transmit, and manage digital medical records by pathologists and other medical specialties in a networked environment. Working Group 1, "Business Modelling in Pathology," has designed main pathology processes - Frozen Study, Formalin Fixed Specimen Study, Telepathology, Cytology, and Autopsy - using Business Process Modelling Notation (BPMN). Working Group 2 has been dedicated to promoting the application of informatics standards in pathology, collaborating with Integrating Healthcare Enterprise (IHE), Digital Imaging and Communications in Medicine (DICOM), Health Level Seven (HL7), and other standardization bodies. Health terminology standardization research has become a topic of great interest. Future research work should focus on standardizing automatic image analysis and tissue microarrays imaging.

  17. Is CR39 worth the effort?

    International Nuclear Information System (INIS)

    Griffith, R.V.

    1987-01-01

    CR39 proton sensitive track detectors were greeted by the radiation protection community at the end of the last decade as a major breakthrough for personnel neutron dosimetry. A number of laboratories eagerly began research on application of CR39 to their dosimetry needs. However, in the last two or three years the enthusiasm has subsided, and many health physicists have stopped working with the material. The number of participants using CR39 in the Oak Ridge National Laboratory Personnel Intercomparison Studies dropped from six in 1985 to three in 1986. On a national level, the Federal Republic of Germany with researchers active in CR39 research recently adopted an albedo system as their national standard. In contrast, the United States Department of Energy (DOE) is supporting development of a CR39 based combination dosimeter to meet Department wide dosimetry needs. The English National Radiological Protection Board (NRPB) now features the use of CR39 in the NRPB PADC(CR39). There has obviously been a range of experiences with CR39 in the dosimetry community. Why has this been the case, and what is the proper role for CR39 in personnel neutron dosimetry. 12 refs., 2 figs., 1 tab

  18. Supporting non proliferation and global security efforts

    International Nuclear Information System (INIS)

    Pochon, E.

    2013-01-01

    CEA contributes as a major actor of France's action against nuclear proliferation and to the strengthening of nuclear security at national level as European and International levels, in particular through the support of the IAEA activities in nuclear non proliferation with the French Support Programme for the IAEA safeguards system and security with the contribution to the IAEA Nuclear Security Plan and cooperation projects with the European Commission. The CEA is a French government funded technological research organization, organized around 5 branches: Nuclear Energy, Technological Researches, Defence (DAM), Material Sciences and Life Sciences. Within the scope of its activities, CEA covers most of the research areas and techniques in nuclear non-proliferation and security. The CEA is also the advisor of the French Government on nuclear policy. Treaty monitoring and the development and implementation of non proliferation and global security programs is an important mission of DAM which rely on nuclear weapons manufacture and past testing experience. The programmes on non proliferation and global security carried out to fulfil DAM's mission cover the following areas: development of monitoring and detection methods and equipments, country profiles and nuclear stockpiles assessment, arms control instruments, proliferation resistance of nuclear fuel cycle, monitoring of nuclear tests, operation and maintenance of national detection capabilities and contribution to CTBT verification systems. (A.C.)

  19. Secondary recurrent miscarriage is associated with previous male birth.

    LENUS (Irish Health Repository)

    Ooi, Poh Veh

    2012-01-31

    Secondary recurrent miscarriage (RM) is defined as three or more consecutive pregnancy losses after delivery of a viable infant. Previous reports suggest that a firstborn male child is associated with less favourable subsequent reproductive potential, possibly due to maternal immunisation against male-specific minor histocompatibility antigens. In a retrospective cohort study of 85 cases of secondary RM we aimed to determine if secondary RM was associated with (i) gender of previous child, maternal age, or duration of miscarriage history, and (ii) increased risk of pregnancy complications. Fifty-three women (62.0%; 53\\/85) gave birth to a male child prior to RM compared to 32 (38.0%; 32\\/85) who gave birth to a female child (p=0.002). The majority (91.7%; 78\\/85) had uncomplicated, term deliveries and normal birth weight neonates, with one quarter of the women previously delivered by Caesarean section. All had routine RM investigations and 19.0% (16\\/85) had an abnormal result. Fifty-seven women conceived again and 33.3% (19\\/57) miscarried, but there was no significant difference in failure rates between those with a previous male or female child (13\\/32 vs. 6\\/25, p=0.2). When patients with abnormal results were excluded, or when women with only one previous child were considered, there was still no difference in these rates. A previous male birth may be associated with an increased risk of secondary RM but numbers preclude concluding whether this increases recurrence risk. The suggested association with previous male birth provides a basis for further investigations at a molecular level.

  20. Secondary recurrent miscarriage is associated with previous male birth.

    LENUS (Irish Health Repository)

    Ooi, Poh Veh

    2011-01-01

    Secondary recurrent miscarriage (RM) is defined as three or more consecutive pregnancy losses after delivery of a viable infant. Previous reports suggest that a firstborn male child is associated with less favourable subsequent reproductive potential, possibly due to maternal immunisation against male-specific minor histocompatibility antigens. In a retrospective cohort study of 85 cases of secondary RM we aimed to determine if secondary RM was associated with (i) gender of previous child, maternal age, or duration of miscarriage history, and (ii) increased risk of pregnancy complications. Fifty-three women (62.0%; 53\\/85) gave birth to a male child prior to RM compared to 32 (38.0%; 32\\/85) who gave birth to a female child (p=0.002). The majority (91.7%; 78\\/85) had uncomplicated, term deliveries and normal birth weight neonates, with one quarter of the women previously delivered by Caesarean section. All had routine RM investigations and 19.0% (16\\/85) had an abnormal result. Fifty-seven women conceived again and 33.3% (19\\/57) miscarried, but there was no significant difference in failure rates between those with a previous male or female child (13\\/32 vs. 6\\/25, p=0.2). When patients with abnormal results were excluded, or when women with only one previous child were considered, there was still no difference in these rates. A previous male birth may be associated with an increased risk of secondary RM but numbers preclude concluding whether this increases recurrence risk. The suggested association with previous male birth provides a basis for further investigations at a molecular level.

  1. Researching research

    DEFF Research Database (Denmark)

    Pais, Alexandre; Valero, Paola

    2012-01-01

    We discuss contemporary theories in mathematics education in order to do research on research. Our strategy consists of analysing discursively and ideologically recent key publications addressing the role of theory in mathematics education research. We examine how the field fabricates its object...... of research by deploying Foucault’s notion of bio-politics - mainly to address the object “learning” - and Žižek’s ideology critique - to address the object “mathematics”. These theories, which have already been used in the field to research teaching and learning, have a great potential to contribute...... to a reflexivity of research on its discourses and effects. Furthermore, they enable us to present a clear distinction between what has been called the sociopolitical turn in mathematics education research and what we call a positioning of mathematics education (research) practices in the Political....

  2. Measuring cognitive load: performance, mental effort and simulation task complexity.

    Science.gov (United States)

    Haji, Faizal A; Rojas, David; Childs, Ruth; de Ribaupierre, Sandrine; Dubrowski, Adam

    2015-08-01

    Interest in applying cognitive load theory in health care simulation is growing. This line of inquiry requires measures that are sensitive to changes in cognitive load arising from different instructional designs. Recently, mental effort ratings and secondary task performance have shown promise as measures of cognitive load in health care simulation. We investigate the sensitivity of these measures to predicted differences in intrinsic load arising from variations in task complexity and learner expertise during simulation-based surgical skills training. We randomly assigned 28 novice medical students to simulation training on a simple or complex surgical knot-tying task. Participants completed 13 practice trials, interspersed with computer-based video instruction. On trials 1, 5, 9 and 13, knot-tying performance was assessed using time and movement efficiency measures, and cognitive load was assessed using subjective rating of mental effort (SRME) and simple reaction time (SRT) on a vibrotactile stimulus-monitoring secondary task. Significant improvements in knot-tying performance (F(1.04,24.95)  = 41.1, p cognitive load (F(2.3,58.5)  = 57.7, p load among novices engaged in simulation-based learning. These measures can be used to track cognitive load during skills training. Mental effort ratings are also sensitive to small differences in intrinsic load arising from variations in the physical complexity of a simulation task. The complementary nature of these subjective and objective measures suggests their combined use is advantageous in simulation instructional design research. © 2015 John Wiley & Sons Ltd.

  3. Erlotinib-induced rash spares previously irradiated skin

    International Nuclear Information System (INIS)

    Lips, Irene M.; Vonk, Ernest J.A.; Koster, Mariska E.Y.; Houwing, Ronald H.

    2011-01-01

    Erlotinib is an epidermal growth factor receptor inhibitor prescribed to patients with locally advanced or metastasized non-small cell lung carcinoma after failure of at least one earlier chemotherapy treatment. Approximately 75% of the patients treated with erlotinib develop acneiform skin rashes. A patient treated with erlotinib 3 months after finishing concomitant treatment with chemotherapy and radiotherapy for non-small cell lung cancer is presented. Unexpectedly, the part of the skin that had been included in his previously radiotherapy field was completely spared from the erlotinib-induced acneiform skin rash. The exact mechanism of erlotinib-induced rash sparing in previously irradiated skin is unclear. The underlying mechanism of this phenomenon needs to be explored further, because the number of patients being treated with a combination of both therapeutic modalities is increasing. The therapeutic effect of erlotinib in the area of the previously irradiated lesion should be assessed. (orig.)

  4. Reasoning with Previous Decisions: Beyond the Doctrine of Precedent

    DEFF Research Database (Denmark)

    Komárek, Jan

    2013-01-01

    in different jurisdictions use previous judicial decisions in their argument, we need to move beyond the concept of precedent to a wider notion, which would embrace practices and theories in legal systems outside the Common law tradition. This article presents the concept of ‘reasoning with previous decisions...... law method’, but they are no less rational and intellectually sophisticated. The reason for the rather conceited attitude of some comparatists is in the dominance of the common law paradigm of precedent and the accompanying ‘case law method’. If we want to understand how courts and lawyers......’ as such an alternative and develops its basic models. The article first points out several shortcomings inherent in limiting the inquiry into reasoning with previous decisions by the common law paradigm (1). On the basis of numerous examples provided in section (1), I will present two basic models of reasoning...

  5. [Prevalence of previously diagnosed diabetes mellitus in Mexico.

    Science.gov (United States)

    Rojas-Martínez, Rosalba; Basto-Abreu, Ana; Aguilar-Salinas, Carlos A; Zárate-Rojas, Emiliano; Villalpando, Salvador; Barrientos-Gutiérrez, Tonatiuh

    2018-01-01

    To compare the prevalence of previously diagnosed diabetes in 2016 with previous national surveys and to describe treatment and its complications. Mexico's national surveys Ensa 2000, Ensanut 2006, 2012 and 2016 were used. For 2016, logistic regression models and measures of central tendency and dispersion were obtained. The prevalence of previously diagnosed diabetes in 2016 was 9.4%. The increase of 2.2% relative to 2012 was not significant and only observed in patients older than 60 years. While preventive measures have increased, the access to medical treatment and lifestyle has not changed. The treatment has been modified, with an increase in insulin and decrease in hypoglycaemic agents. Population aging, lack of screening actions and the increase in diabetes complications will lead to an increase on the burden of disease. Policy measures targeting primary and secondary prevention of diabetes are crucial.

  6. Analysis of over 10,000 Cases finds no association between previously reported candidate polymorphisms and ovarian cancer outcome

    DEFF Research Database (Denmark)

    White, Kristin L; Vierkant, Robert A; Fogarty, Zachary C

    2013-01-01

    Ovarian cancer is a leading cause of cancer-related death among women. In an effort to understand contributors to disease outcome, we evaluated single-nucleotide polymorphisms (SNP) previously associated with ovarian cancer recurrence or survival, specifically in angiogenesis, inflammation, mitosis...

  7. Cardiovascular magnetic resonance in adults with previous cardiovascular surgery.

    Science.gov (United States)

    von Knobelsdorff-Brenkenhoff, Florian; Trauzeddel, Ralf Felix; Schulz-Menger, Jeanette

    2014-03-01

    Cardiovascular magnetic resonance (CMR) is a versatile non-invasive imaging modality that serves a broad spectrum of indications in clinical cardiology and has proven evidence. Most of the numerous applications are appropriate in patients with previous cardiovascular surgery in the same manner as in non-surgical subjects. However, some specifics have to be considered. This review article is intended to provide information about the application of CMR in adults with previous cardiovascular surgery. In particular, the two main scenarios, i.e. following coronary artery bypass surgery and following heart valve surgery, are highlighted. Furthermore, several pictorial descriptions of other potential indications for CMR after cardiovascular surgery are given.

  8. Collaborative Efforts Driving Progress in Pediatric Acute Myeloid Leukemia

    Science.gov (United States)

    Zwaan, C. Michel; Kolb, Edward A.; Reinhardt, Dirk; Abrahamsson, Jonas; Adachi, Souichi; Aplenc, Richard; De Bont, Eveline S.J.M.; De Moerloose, Barbara; Dworzak, Michael; Gibson, Brenda E.S.; Hasle, Henrik; Leverger, Guy; Locatelli, Franco; Ragu, Christine; Ribeiro, Raul C.; Rizzari, Carmelo; Rubnitz, Jeffrey E.; Smith, Owen P.; Sung, Lillian; Tomizawa, Daisuke; van den Heuvel-Eibrink, Marry M.; Creutzig, Ursula; Kaspers, Gertjan J.L.

    2015-01-01

    Diagnosis, treatment, response monitoring, and outcome of pediatric acute myeloid leukemia (AML) have made enormous progress during the past decades. Because AML is a rare type of childhood cancer, with an incidence of approximately seven occurrences per 1 million children annually, national and international collaborative efforts have evolved. This overview describes these efforts and includes a summary of the history and contributions of each of the main collaborative pediatric AML groups worldwide. The focus is on translational and clinical research, which includes past, current, and future clinical trials. Separate sections concern acute promyelocytic leukemia, myeloid leukemia of Down syndrome, and relapsed AML. A plethora of novel antileukemic agents that have emerged, including new classes of drugs, are summarized as well. Finally, an important aspect of the treatment of pediatric AML—supportive care—and late effects are discussed. The future is bright, with a wide range of emerging innovative therapies and with more and more international collaboration that ultimately aim to cure all children with AML, with fewer adverse effects and without late effects. PMID:26304895

  9. Trait Anticipatory Pleasure Predicts Effort Expenditure for Reward.

    Directory of Open Access Journals (Sweden)

    Joachim T Geaney

    Full Text Available Research in motivation and emotion has been increasingly influenced by the perspective that processes underpinning the motivated approach of rewarding goals are distinct from those underpinning enjoyment during reward consummation. This distinction recently inspired the construction of the Temporal Experience of Pleasure Scale (TEPS, a self-report measure that distinguishes trait anticipatory pleasure (pre-reward feelings of desire from consummatory pleasure (feelings of enjoyment and gratification upon reward attainment. In a university community sample (N = 97, we examined the TEPS subscales as predictors of (1 the willingness to expend effort for monetary rewards, and (2 affective responses to a pleasant mood induction procedure. Results showed that both anticipatory pleasure and a well-known trait measure of reward motivation predicted effort-expenditure for rewards when the probability of being rewarded was relatively low. Against expectations, consummatory pleasure was unrelated to induced pleasant affect. Taken together, our findings provide support for the validity of the TEPS anticipatory pleasure scale, but not the consummatory pleasure scale.

  10. Organized Out-of-School Activities and Peer Relationships: Theoretical Perspectives and Previous Research

    Science.gov (United States)

    Fredricks, Jennifer A.; Simpkins, Sandra D.

    2013-01-01

    The goal of this volume is to show how organized activities provide an ideal setting for developing a deeper understanding of peer relations, as well as offering a context for a more positive study of peers. The chapters in this volume focus on youth 10 to 18 years of age. In this introductory chapter we first describe the reasons why organized…

  11. Including Performance Assessments in Accountability Systems: A Review of Scale-Up Efforts

    Science.gov (United States)

    Tung, Rosann

    2010-01-01

    The purpose of this literature and field review is to understand previous efforts at scaling up performance assessments for use across districts and states. Performance assessments benefit students and teachers by providing more opportunities for students to demonstrate their knowledge and complex skills, by providing teachers with better…

  12. Effortful semantic decision-making boosts memory performance in older adults

    NARCIS (Netherlands)

    Fu, L.; Maes, J.H.R.; Varma, S.; Kessels, R.P.C.; Daselaar, S.M.

    2017-01-01

    A major concern in age-related cognitive decline is episodic memory (EM). Previous studies indicate that both resource and binding deficits contribute to EM decline. Environmental support by task manipulations encouraging stronger cognitive effort and deeper levels of processing may facilitate

  13. Convincing American Women to Join in the Efforts to Win World War I: A Lesson Plan.

    Science.gov (United States)

    Sunal, Cynthia S.; Haas, Mary E.

    1994-01-01

    Asserts that World War I, unlike previous wars, was not fought by small groups of professional soldiers, but with large groups of citizens, including women. Presents a lesson plan using poster and postcards that examines methods used by the U.S. government to rally women to join the war effort. (CFR)

  14. Activation of the cannabinoid system in the nucleus accumbens affects effort-based decision making.

    Science.gov (United States)

    Fatahi, Zahra; Haghparast, Abbas

    2018-02-01

    Effort-based decision making addresses how we make an action choice based on an integration of action and goal values. The nucleus accumbens (NAc) is implicated in allowing an animal to overcome effort constraints to obtain greater benefits, and it has been previously shown that cannabis derivatives may affect such processes. Therefore, in this study, we intend to evaluate the involvement of the cannabinoid system in the entire NAc on effort-based decision making. Rats were trained in a T-maze cost-benefit decision making the task in which they could choose either to climb a barrier to obtain a large reward in one arm or run into the other arm without a barrier to obtaining a small reward. Following training, the animals were bilaterally implanted with guide cannulae in the NAc. On test day, rats received cannabinoid agonist (Win 55,212-2; 2, 10 and 50μM) and/or antagonist (AM251; 45μM), afterward percentage of large reward choice and latency of reward attainment were investigated. Results revealed that the administration of cannabinoid agonist led to decrease of large reward choice percentage such that the animals preferred to receive a small reward with low effort instead of receiving a large reward with high effort. The administration of antagonist solely did not affect effort-based decision making, but did attenuate the Win 55,212-2-induced impairments in effort allocation. In agonist-treated animals, the latency of reward collection increased. Moreover, when the effort was equated on both arms, the animals returned to choosing large reward showing that obtained results were not caused by spatial memory impairment. Our finding suggested that activation of the cannabinoid system in the NAc impaired effort-based decision making and led to rats were less willing to invest the physical effort to gain large reward. Copyright © 2017 Elsevier Inc. All rights reserved.

  15. Organizing the HIV vaccine development effort.

    Science.gov (United States)

    Voronin, Yegor; Snow, William

    2013-09-01

    To describe and compare the diverse organizational structures and funding mechanisms applied to advance HIV preventive vaccine research and development and to help explain and inform evolving infrastructures and collaborative funding models. On the basis of models that have been tried, improved or abandoned over three decades, the field seems to have settled into a relatively stable set of diverse initiatives, each with its own organizational signature. At the same time, this set of organizations is forging cross-organizational collaborations, which promise to acquire newly emergent beneficial properties. Strong motivation to expedite HIV vaccine R&D has driven a diversity of customized and inventive organizational approaches, largely government and foundation funded. Although no one approach has proven a panacea, the field has evolved into a constellation of often overlapping organizations that complement or reinforce one another. The Global HIV Vaccine Enterprise, a responsive, rapidly evolving loose infrastructure, is an innovative collaboration to catalyze that evolution.

  16. Squamous cell carcinoma arising in previously burned or irradiated skin

    International Nuclear Information System (INIS)

    Edwards, M.J.; Hirsch, R.M.; Broadwater, J.R.; Netscher, D.T.; Ames, F.C.

    1989-01-01

    Squamous cell carcinoma (SCC) arising in previously burned or irradiated skin was reviewed in 66 patients treated between 1944 and 1986. Healing of the initial injury was complicated in 70% of patients. Mean interval from initial injury to diagnosis of SCC was 37 years. The overwhelming majority of patients presented with a chronic intractable ulcer in previously injured skin. The regional relapse rate after surgical excision was very high, 58% of all patients. Predominant patterns of recurrence were in local skin and regional lymph nodes (93% of recurrences). Survival rates at 5, 10, and 20 years were 52%, 34%, and 23%, respectively. Five-year survival rates in previously burned and irradiated patients were not significantly different (53% and 50%, respectively). This review, one of the largest reported series, better defines SCC arising in previously burned or irradiated skin as a locally aggressive disease that is distinct from SCC arising in sunlight-damaged skin. An increased awareness of the significance of chronic ulceration in scar tissue may allow earlier diagnosis. Regional disease control and survival depend on surgical resection of all known disease and may require radical lymph node dissection or amputation

  17. Outcome Of Pregnancy Following A Previous Lower Segment ...

    African Journals Online (AJOL)

    Background: A previous ceasarean section is an important variable that influences patient management in subsequent pregnancies. A trial of vaginal delivery in such patients is a feasible alternative to a secondary section, thus aiding to reduce the ceasarean section rate and its associated co-morbidities. Objective: To ...

  18. 24 CFR 1710.552 - Previously accepted state filings.

    Science.gov (United States)

    2010-04-01

    ... of Substantially Equivalent State Law § 1710.552 Previously accepted state filings. (a) Materials... and contracts or agreements contain notice of purchaser's revocation rights. In addition see § 1715.15..., unless the developer is obligated to do so in the contract. (b) If any such filing becomes inactive or...

  19. The job satisfaction of principals of previously disadvantaged schools

    African Journals Online (AJOL)

    The aim of this study was to identify influences on the job satisfaction of previously disadvantaged ..... I am still riding the cloud … I hope it lasts. .... as a way of creating a climate and culture in schools where individuals are willing to explore.

  20. Haemophilus influenzae type f meningitis in a previously healthy boy

    DEFF Research Database (Denmark)

    Ronit, Andreas; Berg, Ronan M G; Bruunsgaard, Helle

    2013-01-01

    Non-serotype b strains of Haemophilus influenzae are extremely rare causes of acute bacterial meningitis in immunocompetent individuals. We report a case of acute bacterial meningitis in a 14-year-old boy, who was previously healthy and had been immunised against H influenzae serotype b (Hib...

  1. Cryptococcal meningitis in a previously healthy child | Chimowa ...

    African Journals Online (AJOL)

    An 8-year-old previously healthy female presented with a 3 weeks history of headache, neck stiffness, deafness, fever and vomiting and was diagnosed with cryptococcal meningitis. She had documented hearing loss and was referred to tertiary-level care after treatment with fluconazole did not improve her neurological ...

  2. Investigation of previously derived Hyades, Coma, and M67 reddenings

    International Nuclear Information System (INIS)

    Taylor, B.J.

    1980-01-01

    New Hyades polarimetry and field star photometry have been obtained to check the Hyades reddening, which was found to be nonzero in a previous paper. The new Hyades polarimetry implies essentially zero reddening; this is also true of polarimetry published by Behr (which was incorrectly interpreted in the previous paper). Four photometric techniques which are presumed to be insensitive to blanketing are used to compare the Hyades to nearby field stars; these four techniques also yield essentially zero reddening. When all of these results are combined with others which the author has previously published and a simultaneous solution for the Hyades, Coma, and M67 reddenings is made, the results are E (B-V) =3 +- 2 (sigma) mmag, -1 +- 3 (sigma) mmag, and 46 +- 6 (sigma) mmag, respectively. No support for a nonzero Hyades reddening is offered by the new results. When the newly obtained reddenings for the Hyades, Coma, and M67 are compared with results from techniques given by Crawford and by users of the David Dunlap Observatory photometric system, no differences between the new and other reddenings are found which are larger than about 2 sigma. The author had previously found that the M67 main-sequence stars have about the same blanketing as that of Coma and less blanketing than the Hyades; this conclusion is essentially unchanged by the revised reddenings

  3. 18 CFR 154.302 - Previously submitted material.

    Science.gov (United States)

    2010-04-01

    ... 18 Conservation of Power and Water Resources 1 2010-04-01 2010-04-01 false Previously submitted material. 154.302 Section 154.302 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY... concurrently with the rate change filing. There must be furnished to the Director, Office of Energy Market...

  4. Process cells dismantling of EUREX pant: previous activities

    International Nuclear Information System (INIS)

    Gili, M.

    1998-01-01

    In the '98-'99 period some process cells of the EUREX pant will be dismantled, in order to place there the liquid wastes conditioning plant 'CORA'. This report resumes the previous activities (plant rinsing campaigns and inactive Cell 014 dismantling), run in the past three years and the drawn experience [it

  5. Obstructive pulmonary disease in patients with previous tuberculosis ...

    African Journals Online (AJOL)

    Obstructive pulmonary disease in patients with previous tuberculosis: Pathophysiology of a community-based cohort. B.W. Allwood, R Gillespie, M Galperin-Aizenberg, M Bateman, H Olckers, L Taborda-Barata, G.L. Calligaro, Q Said-Hartley, R van Zyl-Smit, C.B. Cooper, E van Rikxoort, J Goldin, N Beyers, E.D. Bateman ...

  6. Abiraterone in metastatic prostate cancer without previous chemotherapy

    NARCIS (Netherlands)

    Ryan, Charles J.; Smith, Matthew R.; de Bono, Johann S.; Molina, Arturo; Logothetis, Christopher J.; de Souza, Paul; Fizazi, Karim; Mainwaring, Paul; Piulats, Josep M.; Ng, Siobhan; Carles, Joan; Mulders, Peter F. A.; Basch, Ethan; Small, Eric J.; Saad, Fred; Schrijvers, Dirk; van Poppel, Hendrik; Mukherjee, Som D.; Suttmann, Henrik; Gerritsen, Winald R.; Flaig, Thomas W.; George, Daniel J.; Yu, Evan Y.; Efstathiou, Eleni; Pantuck, Allan; Winquist, Eric; Higano, Celestia S.; Taplin, Mary-Ellen; Park, Youn; Kheoh, Thian; Griffin, Thomas; Scher, Howard I.; Rathkopf, Dana E.; Boyce, A.; Costello, A.; Davis, I.; Ganju, V.; Horvath, L.; Lynch, R.; Marx, G.; Parnis, F.; Shapiro, J.; Singhal, N.; Slancar, M.; van Hazel, G.; Wong, S.; Yip, D.; Carpentier, P.; Luyten, D.; de Reijke, T.

    2013-01-01

    Abiraterone acetate, an androgen biosynthesis inhibitor, improves overall survival in patients with metastatic castration-resistant prostate cancer after chemotherapy. We evaluated this agent in patients who had not received previous chemotherapy. In this double-blind study, we randomly assigned

  7. Response to health insurance by previously uninsured rural children.

    Science.gov (United States)

    Tilford, J M; Robbins, J M; Shema, S J; Farmer, F L

    1999-08-01

    To examine the healthcare utilization and costs of previously uninsured rural children. Four years of claims data from a school-based health insurance program located in the Mississippi Delta. All children who were not Medicaid-eligible or were uninsured, were eligible for limited benefits under the program. The 1987 National Medical Expenditure Survey (NMES) was used to compare utilization of services. The study represents a natural experiment in the provision of insurance benefits to a previously uninsured population. Premiums for the claims cost were set with little or no information on expected use of services. Claims from the insurer were used to form a panel data set. Mixed model logistic and linear regressions were estimated to determine the response to insurance for several categories of health services. The use of services increased over time and approached the level of utilization in the NMES. Conditional medical expenditures also increased over time. Actuarial estimates of claims cost greatly exceeded actual claims cost. The provision of a limited medical, dental, and optical benefit package cost approximately $20-$24 per member per month in claims paid. An important uncertainty in providing health insurance to previously uninsured populations is whether a pent-up demand exists for health services. Evidence of a pent-up demand for medical services was not supported in this study of rural school-age children. States considering partnerships with private insurers to implement the State Children's Health Insurance Program could lower premium costs by assembling basic data on previously uninsured children.

  8. A community effort to protect genomic data sharing, collaboration and outsourcing.

    Science.gov (United States)

    Wang, Shuang; Jiang, Xiaoqian; Tang, Haixu; Wang, Xiaofeng; Bu, Diyue; Carey, Knox; Dyke, Stephanie Om; Fox, Dov; Jiang, Chao; Lauter, Kristin; Malin, Bradley; Sofia, Heidi; Telenti, Amalio; Wang, Lei; Wang, Wenhao; Ohno-Machado, Lucila

    2017-01-01

    The human genome can reveal sensitive information and is potentially re-identifiable, which raises privacy and security concerns about sharing such data on wide scales. In 2016, we organized the third Critical Assessment of Data Privacy and Protection competition as a community effort to bring together biomedical informaticists, computer privacy and security researchers, and scholars in ethical, legal, and social implications (ELSI) to assess the latest advances on privacy-preserving techniques for protecting human genomic data. Teams were asked to develop novel protection methods for emerging genome privacy challenges in three scenarios: Track (1) data sharing through the Beacon service of the Global Alliance for Genomics and Health. Track (2) collaborative discovery of similar genomes between two institutions; and Track (3) data outsourcing to public cloud services. The latter two tracks represent continuing themes from our 2015 competition, while the former was new and a response to a recently established vulnerability. The winning strategy for Track 1 mitigated the privacy risk by hiding approximately 11% of the variation in the database while permitting around 160,000 queries, a significant improvement over the baseline. The winning strategies in Tracks 2 and 3 showed significant progress over the previous competition by achieving multiple orders of magnitude performance improvement in terms of computational runtime and memory requirements. The outcomes suggest that applying highly optimized privacy-preserving and secure computation techniques to safeguard genomic data sharing and analysis is useful. However, the results also indicate that further efforts are needed to refine these techniques into practical solutions.

  9. EURATOM achievements and challenges in facilitating Pan-European infrastructure collaborative efforts

    International Nuclear Information System (INIS)

    Garbil, Roger

    2017-01-01

    The European Atomic Energy Community (Euratom) Research and Training framework programmes are benefiting from a consistent success in pursuing excellence in research and facilitating Pan European collaborative efforts across a broad range of nuclear science and technologies, nuclear fission and radiation protection. To fulfil Euratom R and D programmes keys objectives of maintaining high levels of nuclear knowledge and building a more dynamic and competitive European industry, promotion of Pan-European mobility of researchers are implemented by co-financing transnational access to research infrastructures (RIs) and joint research activities. 'Euratom Achievements and Challenges' show the benefits of research efforts in key fields, of building an effective 'critical mass', of promoting the creation of 'centres of excellence' with an increased support for 'open access to key research infrastructures', exploitation of research results, management of knowledge, dissemination and sharing of learning outcomes.

  10. EURATOM achievements and challenges in facilitating Pan-European infrastructure collaborative efforts

    Energy Technology Data Exchange (ETDEWEB)

    Garbil, Roger [European Commission, Brussels (Belgium). DG Research and Innovation, Euratom Fission

    2017-10-15

    The European Atomic Energy Community (Euratom) Research and Training framework programmes are benefiting from a consistent success in pursuing excellence in research and facilitating Pan European collaborative efforts across a broad range of nuclear science and technologies, nuclear fission and radiation protection. To fulfil Euratom R and D programmes keys objectives of maintaining high levels of nuclear knowledge and building a more dynamic and competitive European industry, promotion of Pan-European mobility of researchers are implemented by co-financing transnational access to research infrastructures (RIs) and joint research activities. 'Euratom Achievements and Challenges' show the benefits of research efforts in key fields, of building an effective 'critical mass', of promoting the creation of 'centres of excellence' with an increased support for 'open access to key research infrastructures', exploitation of research results, management of knowledge, dissemination and sharing of learning outcomes.

  11. Laboratory and Field-Based Evaluation of Short-Term Effort with Maximal Intensity in Individuals with Intellectual Disabilities

    Directory of Open Access Journals (Sweden)

    Lencse-Mucha Judit

    2015-12-01

    Full Text Available Results of previous studies have not indicated clearly which tests should be used to assess short-term efforts of people with intellectual disabilities. Thus, the aim of the present study was to evaluate laboratory and field-based tests of short-term effort with maximal intensity of subjects with intellectual disabilities. Twenty four people with intellectual disability, who trained soccer, participated in this study. The 30 s Wingate test and additionally an 8 s test with maximum intensity were performed on a bicycle ergometer. The fatigue index, maximal and mean power, relative maximal and relative mean power were measured. Overall, nine field-based tests were conducted: 5, 10 and 20 m sprints, a 20 m shuttle run, a seated medicine ball throw, a bent arm hang test, a standing broad jump, sit-ups and a hand grip test. The reliability of the 30 s and 8 s Wingate tests for subjects with intellectual disability was confirmed. Significant correlation was observed for mean power between the 30 s and 8 s tests on the bicycle ergometer at a moderate level (r >0.4. Moreover, significant correlations were indicated between the results of laboratory tests and field tests, such as the 20 m sprint, the 20 m shuttle run, the standing long jump and the medicine ball throw. The strongest correlation was in the medicine ball throw. The 30 s Wingate test is a reliable test assessing maximal effort in subjects with intellectual disability. The results of this research confirmed that the 8 s test on a bicycle ergometer had a moderate correlation with the 30 s Wingate test in this population, thus, this comparison needs further investigation to examine alternativeness of the 8 s to 30 s Wingate tests. The non-laboratory tests could be used to indirectly assess performance in short-term efforts with maximal intensity.

  12. Enjoying mathematics or feeling competent in mathematics? Reciprocal effects on mathematics achievement and perceived math effort expenditure.

    Science.gov (United States)

    Pinxten, Maarten; Marsh, Herbert W; De Fraine, Bieke; Van Den Noortgate, Wim; Van Damme, Jan

    2014-03-01

    The multidimensionality of the academic self-concept in terms of domain specificity has been well established in previous studies, whereas its multidimensionality in terms of motivational functions (the so-called affect-competence separation) needs further examination. This study aims at exploring differential effects of enjoyment and competence beliefs on two external validity criteria in the field of mathematics. Data analysed in this study were part of a large-scale longitudinal research project. Following a five-wave design, math enjoyment, math competence beliefs, math achievement, and perceived math effort expenditure measures were repeatedly collected from a cohort of 4,724 pupils in Grades 3-7. Confirmatory factor analysis (CFA) was used to test the internal factor structure of the math self-concept. Additionally, a series of nested models was tested using structural equation modelling to examine longitudinal reciprocal interrelations between math competence beliefs and math enjoyment on the one hand and math achievement and perceived math effort expenditure on the other. Our results showed that CFA models with separate factors for math enjoyment and math competence beliefs fit the data substantially better than models without it. Furthermore, differential relationships between both constructs and the two educational outcomes were observed. Math competence beliefs had positive effects on math achievement and negative effects on perceived math effort expenditure. Math enjoyment had (mild) positive effects on subsequent perceived effort expenditure and math competence beliefs. This study provides further support for the affect-competence separation. Theoretical issues regarding adequate conceptualization and practical consequences for practitioners are discussed. © 2013 The British Psychological Society.

  13. Laboratory and Field-Based Evaluation of Short-Term Effort with Maximal Intensity in Individuals with Intellectual Disabilities

    Science.gov (United States)

    Lencse-Mucha, Judit; Molik, Bartosz; Marszałek, Jolanta; Kaźmierska-Kowalewska, Kalina; Ogonowska-Słodownik, Anna

    2015-01-01

    Results of previous studies have not indicated clearly which tests should be used to assess short-term efforts of people with intellectual disabilities. Thus, the aim of the present study was to evaluate laboratory and field-based tests of short-term effort with maximal intensity of subjects with intellectual disabilities. Twenty four people with intellectual disability, who trained soccer, participated in this study. The 30 s Wingate test and additionally an 8 s test with maximum intensity were performed on a bicycle ergometer. The fatigue index, maximal and mean power, relative maximal and relative mean power were measured. Overall, nine field-based tests were conducted: 5, 10 and 20 m sprints, a 20 m shuttle run, a seated medicine ball throw, a bent arm hang test, a standing broad jump, sit-ups and a hand grip test. The reliability of the 30 s and 8 s Wingate tests for subjects with intellectual disability was confirmed. Significant correlation was observed for mean power between the 30 s and 8 s tests on the bicycle ergometer at a moderate level (r >0.4). Moreover, significant correlations were indicated between the results of laboratory tests and field tests, such as the 20 m sprint, the 20 m shuttle run, the standing long jump and the medicine ball throw. The strongest correlation was in the medicine ball throw. The 30 s Wingate test is a reliable test assessing maximal effort in subjects with intellectual disability. The results of this research confirmed that the 8 s test on a bicycle ergometer had a moderate correlation with the 30 s Wingate test in this population, thus, this comparison needs further investigation to examine alternativeness of the 8 s to 30 s Wingate tests. The non-laboratory tests could be used to indirectly assess performance in short-term efforts with maximal intensity. PMID:26834874

  14. Reoperative sentinel lymph node biopsy after previous mastectomy.

    Science.gov (United States)

    Karam, Amer; Stempel, Michelle; Cody, Hiram S; Port, Elisa R

    2008-10-01

    Sentinel lymph node (SLN) biopsy is the standard of care for axillary staging in breast cancer, but many clinical scenarios questioning the validity of SLN biopsy remain. Here we describe our experience with reoperative-SLN (re-SLN) biopsy after previous mastectomy. Review of the SLN database from September 1996 to December 2007 yielded 20 procedures done in the setting of previous mastectomy. SLN biopsy was performed using radioisotope with or without blue dye injection superior to the mastectomy incision, in the skin flap in all patients. In 17 of 20 patients (85%), re-SLN biopsy was performed for local or regional recurrence after mastectomy. Re-SLN biopsy was successful in 13 of 20 patients (65%) after previous mastectomy. Of the 13 patients, 2 had positive re-SLN, and completion axillary dissection was performed, with 1 having additional positive nodes. In the 11 patients with negative re-SLN, 2 patients underwent completion axillary dissection demonstrating additional negative nodes. One patient with a negative re-SLN experienced chest wall recurrence combined with axillary recurrence 11 months after re-SLN biopsy. All others remained free of local or axillary recurrence. Re-SLN biopsy was unsuccessful in 7 of 20 patients (35%). In three of seven patients, axillary dissection was performed, yielding positive nodes in two of the three. The remaining four of seven patients all had previous modified radical mastectomy, so underwent no additional axillary surgery. In this small series, re-SLN was successful after previous mastectomy, and this procedure may play some role when axillary staging is warranted after mastectomy.

  15. Effortful semantic decision-making boosts memory performance in older adults.

    Science.gov (United States)

    Fu, Li; Maes, Joseph H R; Varma, Samarth; Kessels, Roy P C; Daselaar, Sander M

    2017-04-01

    A major concern in age-related cognitive decline is episodic memory (EM). Previous studies indicate that both resource and binding deficits contribute to EM decline. Environmental support by task manipulations encouraging stronger cognitive effort and deeper levels of processing may facilitate compensation for these two deficits. To clarify factors that can counteract age-related EM decline, we assessed effects of cognitive effort (four levels) and level of processing (LoP, shallow/deep) during encoding on subsequent retrieval. Young (YAs, N = 23) and older (OAs, N = 23) adults performed two incidental encoding tasks, deep/semantic and shallow/perceptual. Cognitive effort was manipulated by varying decision-making demands. EM performance, indexed by d-prime, was later tested using a recognition task. Results showed that regardless of LoP, increased cognitive effort caused higher d-primes in both age groups. Compared to YAs, OAs showed a lower d-prime after shallow encoding across all cognitive effort levels, and after deep encoding with low cognitive effort. Deep encoding with higher levels of cognitive effort completely eliminated these age differences. Our findings support an environmental-compensatory account of cognitive ageing and can have important therapeutic implications.

  16. The power of competition: Effects of social motivation on attention, sustained physical effort, and learning

    Directory of Open Access Journals (Sweden)

    Brynne Catherine DiMenichi

    2015-09-01

    Full Text Available Competition has often been implicated as a means to improve effort-based learning and attention. Two experiments examined the effects of competition on effort and memory. In Experiment 1, participants completed a physical effort task in which they were rewarded for winning an overall percentage, or for winning a competition they believed was against another player. In Experiment 2, participants completed a memory task in which they were rewarded for remembering an overall percentage of shapes, or more shapes than a competitor. We found that, in the physical effort task, participants demonstrated faster reaction times—a previous indicator of increased attention— in the competitive environment. Moreover, individual differences predicted the salience of competition’s effect. Furthermore, male participants showed faster reaction times and greater sustained effort as a result of a competitive environment, suggesting that males may be more affected by competition in physical effort tasks. However, in Experiment 2, participants remembered fewer shapes when competing, and later recalled less of these shapes during a post-test, suggesting that competition was harmful in our memory task. The different results from these two experiments suggest that competition can improve attention in a physical effort task, yet caution the use of competition in memory tasks.

  17. The effects of savings on reservation wages and search effort

    NARCIS (Netherlands)

    Lammers, M.

    2014-01-01

    This paper discusses the interrelations among wealth, reservation wages and search effort. A theoretical job search model predicts wealth to affect reservation wages positively, and search effort negatively. Subsequently, reduced form equations for reservation wages and search intensity take these

  18. Effort levels of the partners in networked manufacturing

    Science.gov (United States)

    Chai, G. R.; Cai, Z.; Su, Y. N.; Zong, S. L.; Zhai, G. Y.; Jia, J. H.

    2017-08-01

    Compared with traditional manufacturing mode, could networked manufacturing improve effort levels of the partners? What factors will affect effort level of the partners? How to encourage the partners to improve their effort levels? To answer these questions, we introduce network effect coefficient to build effort level model of the partners in networked manufacturing. The results show that (1) with the increase of the network effect in networked manufacturing, the actual effort level can go beyond the ideal level of traditional manufacturing. (2) Profit allocation based on marginal contribution rate would help improve effort levels of the partners in networked manufacturing. (3) The partners in networked manufacturing who wishes to have a larger distribution ratio must make a higher effort level, and enterprises with insufficient effort should be terminated in networked manufacturing.

  19. EURATOM Success Stories in Facilitating Pan-European E&T Collaborative Efforts

    International Nuclear Information System (INIS)

    Garbil, R.

    2016-01-01

    Full text: The European Atomic Energy Community (Euratom) Research and Training framework programmes are benefiting from a consistent success in pursuing excellence in research and facilitating Pan-European collaborative efforts across a broad range of nuclear science and technologies, nuclear fission and radiation protection. To fulfil Euratom R&D programmes keys objectives of maintaining high levels of nuclear knowledge and building a more dynamic and competitive European industry, promotion of Pan-European mobility of researchers are implemented by co-financing transnational access to research infrastructures and joint research activities through to research and innovation and coordination and support actions funding schemes. Establishment by the research community of European technology platforms are being capitalized. Mapping of research infrastructures and E&T capabilities is allowing a closer cooperation within the European Union and beyond, benefiting from multilateral international agreements and from closer cooperation between Euratom, OECD/NEA and IAEA and international fora. “Euratom success stories” in facilitating Pan-European E&T collaborative efforts through research and training framework programmes show the benefits of research efforts in key fields, of building an effective “critical mass”, of promoting the creation of “centres of excellence” with an increased support for “open access to key research infrastructures”, exploitation of research results, management of knowledge, dissemination and sharing of learning outcomes. (author

  20. Fontan Surgical Planning: Previous Accomplishments, Current Challenges, and Future Directions.

    Science.gov (United States)

    Trusty, Phillip M; Slesnick, Timothy C; Wei, Zhenglun Alan; Rossignac, Jarek; Kanter, Kirk R; Fogel, Mark A; Yoganathan, Ajit P

    2018-04-01

    The ultimate goal of Fontan surgical planning is to provide additional insights into the clinical decision-making process. In its current state, surgical planning offers an accurate hemodynamic assessment of the pre-operative condition, provides anatomical constraints for potential surgical options, and produces decent post-operative predictions if boundary conditions are similar enough between the pre-operative and post-operative states. Moving forward, validation with post-operative data is a necessary step in order to assess the accuracy of surgical planning and determine which methodological improvements are needed. Future efforts to automate the surgical planning process will reduce the individual expertise needed and encourage use in the clinic by clinicians. As post-operative physiologic predictions improve, Fontan surgical planning will become an more effective tool to accurately model patient-specific hemodynamics.

  1. Perceived effort for motor control and decision-making.

    Directory of Open Access Journals (Sweden)

    Ignasi Cos

    2017-08-01

    Full Text Available How effort is internally quantified and how it influences both movement generation and decisions between potential movements are 2 difficult questions to answer. Physical costs are known to influence motor control and decision-making, yet we lack a general, principled characterization of how the perception of effort operates across tasks and conditions. Morel and colleagues introduce an insightful approach to that end, assessing effort indifference points and presenting a quadratic law between perceived effort and force production.

  2. Chair Talk: Resources to Maximize Administrative Efforts

    Science.gov (United States)

    MacDonald, H.; Chan, M. A.; Bierly, E. W.; Manduca, C. A.; Ormand, C. J.

    2009-12-01

    Earth science department chairs are generally scientists who have little/no formal administrative training. The common rotation of faculty members in three-six year cycles distributes the heavy leadership responsibilities but involves little preparation beforehand to deal with budgets, fundraising, personnel issues, confrontations, and crises. The amount of information exchange and support upon exit and handoff to the next chair is variable. Resources for chairs include workshops, meetings (ranging from annual meetings of geoscience chairs to monthly meetings of small groups of chairs from various disciplines on a campus), discussions, and online resources. These resources, some of which we designed in the past several years, provide information and support for chairs, help them share best practices, and reduce time spent “reinventing the wheel”. Most of these resources involve groups of chairs in our discipline who meet together. The AGU Board of Heads and Chairs of Earth and Space Science Departments offers annual one-day workshops at the Fall AGU meeting. The specific topics vary from year to year; they have included goals and roles of heads and chairs, fundraising and Advisory Boards, student recruitment, interdisciplinarity, dual-career couples, and undergraduate research. The workshop provides ample opportunities for open discussion. Annual one-two day meetings of groups of geoscience department chairs (e.g., research universities in a particular region) provide an opportunity for chairs to share specific data about their departments (e.g., salaries, graduate student stipends, information about facilities) and discuss strategies. At the College of William and Mary, a small group of chairs meets monthly throughout the year; each session includes time for open discussion as well as a more structured discussion on a particular topic (e.g., merit review, development and fundraising, mentoring early career faculty and the tenure process, leadership styles

  3. Instrument demonstration effort for the CLARREO mission

    Science.gov (United States)

    Grandmont, Frédéric; Moreau, Louis; Bourque, Hugo; Taylor, Joe; Girard, Frédéric; Larouche, Martin; Veilleux, James

    2017-11-01

    NASA and other national agencies ask the National Research Council (NRC) once every decade to look out ten or more years into the future and prioritize research areas, observations, and notional missions to make those observations. The latest such scientific community consultation referred to as the Decadal Survey (DS), was completed in 2007 [1]. DS thematic panels developed 35 missions from more than 100 missions proposed, from which the DS Executive Committee synthesized 17 missions, with suggested order presented in three time-phased blocks. The first block with aim for near term launch (2010-2013) included four missions. The Climate Absolute Radiance and Refractivity Observatory (CLARREO) mission is one of them. The CLARREO mission was classified as a Small Mission to be contained in a 300 M US$ budgetary envelope. CLARREO will provide a benchmark climate record that is global, accurate in perpetuity, tested against independent strategies that reveal systematic errors, and pinned to international standards. The long term objective thus suggests that NOAA or NASA will fly the CLARREO instrument suite on an operational basis following the first scientific experiment The CLARREO missions will conduct the following observations: 1. Absolute spectrally-resolved measurements of terrestrial thermal emission with an absolute accuracy of 0.1 K in brightness temperature (3σ or 99% confidence limits.) The measurements should cover most of the thermal spectrum. 2. Absolute spectrally-resolved measurements of the solar radiation reflected from Earth. The measurements should cover the part of the solar spectrum most important to climate, including the near-ultraviolet, visible, and near-infrared. 3. Independent measurements of atmospheric temperature, pressure, and humidity using Global Positioning System (GPS) occultation measurements of atmospheric refraction. 4. Serve as a high accuracy calibration standard for use by the broadband CERES instruments on-orbit. Following

  4. [Fatal amnioinfusion with previous choriocarcinoma in a parturient woman].

    Science.gov (United States)

    Hrgović, Z; Bukovic, D; Mrcela, M; Hrgović, I; Siebzehnrübl, E; Karelovic, D

    2004-04-01

    The case of 36-year-old tercipare is described who developed choriocharcinoma in a previous pregnancy. During the first term labour the patient developed cardiac arrest, so reanimation and sectio cesarea was performed. A male new-born was delivered in good condition, but even after intensive therapy and reanimation occurred death of parturient woman with picture of disseminate intravascular coagulopathia (DIK). On autopsy and on histology there was no sign of malignant disease, so it was not possible to connect previous choricarcinoma with amniotic fluid embolism. Maybe was place of choriocarcinoma "locus minoris resistentiae" which later resulted with failure in placentation what was hard to prove. On autopsy we found embolia of lung with a microthrombosis of terminal circulation with punctiformis bleeding in mucous, what stands for DIK.

  5. Previously unreported abnormalities in Wolfram Syndrome Type 2.

    Science.gov (United States)

    Akturk, Halis Kaan; Yasa, Seda

    2017-01-01

    Wolfram syndrome (WFS) is a rare autosomal recessive disease with non-autoimmune childhood onset insulin dependent diabetes and optic atrophy. WFS type 2 (WFS2) differs from WFS type 1 (WFS1) with upper intestinal ulcers, bleeding tendency and the lack ofdiabetes insipidus. Li-fespan is short due to related comorbidities. Only a few familieshave been reported with this syndrome with the CISD2 mutation. Here we report two siblings with a clinical diagnosis of WFS2, previously misdiagnosed with type 1 diabetes mellitus and diabetic retinopathy-related blindness. We report possible additional clinical and laboratory findings that have not been pre-viously reported, such as asymptomatic hypoparathyroidism, osteomalacia, growth hormone (GH) deficiency and hepatomegaly. Even though not a requirement for the diagnosis of WFS2 currently, our case series confirm hypogonadotropic hypogonadism to be also a feature of this syndrome, as reported before. © Polish Society for Pediatric Endocrinology and Diabetology.

  6. The middle manager role in energy company environmental efforts

    Science.gov (United States)

    Fischhoff, Maya E.

    2005-12-01

    This research examines the internal organizational processes determining corporate environmental action. Corporations have a tremendous environmental impact, yet relatively little is known about how employees within them view and work on these issues. The research focused on middle managers, a level of the company whose value is often questioned. Interviews were conducted with 70 middle managers at two energy companies (comprising utilities and unregulated businesses). Interviews examined the shape and significance of middle manager involvement in environmental issues, looking specifically at what issues middle managers deal with, what goals they pursue, and what approaches they use. The research finds middle managers' roles with respect to environmental issues to be far-reaching and complex. Much of their effort is focused on meeting regulatory requirements ("complying"). They are committed to compliance, in part for ethical reasons, but often find regulations frustrating and costly. Compliance is more challenging than commonly thought; it demands time, knowledge, and substantial creativity. In pursuing it, interviewees work with employees throughout the organization. This research shows middle managers interacting with those hierarchically above and below them in ways that greatly modify earlier portrayals of middle managers. Earlier portrayals often emphasized struggles for power within the organization. Here, middle managers work in ways best characterized as collaborative and supportive. Middle managers also have extensive involvement laterally within the company and with groups outside the company. These links have received modest attention in literature, yet are found to be terribly important. Middle managers' lateral efforts inside the company, often on teams, allow diverse expertise (e.g., from people in different functions) to be applied to environmental issues. Documenting middle managers' involvement externally, with governmental officials and sectors

  7. Influence of previous knowledge in Torrance tests of creative thinking

    OpenAIRE

    Aranguren, María; Consejo Nacional de Investigaciones Científicas y Técnicas CONICET

    2015-01-01

    The aim of this work is to analyze the influence of study field, expertise and recreational activities participation in Torrance Tests of Creative Thinking (TTCT, 1974) performance. Several hypotheses were postulated to explore the possible effects of previous knowledge in TTCT verbal and TTCT figural university students’ outcomes. Participants in this study included 418 students from five study fields: Psychology;Philosophy and Literature, Music; Engineering; and Journalism and Advertisin...

  8. Goal Setting and Expectancy Theory Predictions of Effort and Performance.

    Science.gov (United States)

    Dossett, Dennis L.; Luce, Helen E.

    Neither expectancy (VIE) theory nor goal setting alone are effective determinants of individual effort and task performance. To test the combined ability of VIE and goal setting to predict effort and performance, 44 real estate agents and their managers completed questionnaires. Quarterly income goals predicted managers' ratings of agents' effort,…

  9. Innovation and performance outcomes of market information collection efforts : The role of top management team involvement

    NARCIS (Netherlands)

    Harmancioglu, Nukhet; Grinstein, A.; Goldman, Arieh

    Research on organizational market information processing in marketing has not yet examined a key issue associated with information collection: the role of top management team (TMT) involvement. Research in marketing has typically studied market information collection efforts from the perspective of

  10. Exploring the Identity-Theft Prevention Efforts of Consumers in the United States

    Science.gov (United States)

    Lewis, Jacquelyne L.

    2011-01-01

    Identity theft is quite expensive and devastating for victims; unfortunately, it is also a rapidly growing crime. Much of the prior research on identity theft has focused on legislative efforts that may prevent the crime. However, limited research exists on what consumers perceive as identity prevention and the measures they take to prevent…

  11. Analysis of previous screening examinations for patients with breast cancer

    International Nuclear Information System (INIS)

    Lee, Eun Hye; Cha, Joo Hee; Han, Dae Hee; Choi, Young Ho; Hwang, Ki Tae; Ryu, Dae Sik; Kwak, Jin Ho; Moon, Woo Kyung

    2007-01-01

    We wanted to improve the quality of subsequent screening by reviewing the previous screening of breast cancer patients. Twenty-four breast cancer patients who underwent previous screening were enrolled. All 24 took mammograms and 15 patients also took sonograms. We reviewed the screening retrospectively according to the BI-RADS criteria and we categorized the results into false negative, true negative, true positive and occult cancers. We also categorized the causes of false negative cancers into misperception, misinterpretation and technical factors and then we analyzed the attributing factors. Review of the previous screening revealed 66.7% (16/24) false negative, 25.0% (6/24) true negative, and 8.3% (2/24) true positive cancers. False negative cancers were caused by the mammogram in 56.3% (9/16) and by the sonogram in 43.7% (7/16). For the false negative cases, all of misperception were related with mammograms and this was attributed to dense breast, a lesion located at the edge of glandular tissue or the image, and findings seen on one view only. Almost all misinterpretations were related with sonograms and attributed to loose application of the final assessment. To improve the quality of breast screening, it is essential to overcome the main causes of false negative examinations, including misperception and misinterpretation. We need systematic education and strict application of final assessment categories of BI-RADS. For effective communication among physicians, it is also necessary to properly educate them about BI-RADS

  12. Analysis of Product Buying Decision on Lazada E-commerce based on Previous Buyers’ Comments

    Directory of Open Access Journals (Sweden)

    Neil Aldrin

    2017-06-01

    Full Text Available The aims of the present research are: 1 to know that product buying decision possibly occurs, 2 to know how product buying decision occurs on Lazada e-commerce’s customers, 3 how previous buyers’ comments can increase product buying decision on Lazada e-commerce. This research utilizes qualitative research method. Qualitative research is a research that investigates other researches and makes assumption or discussion result so that other analysis results can be made in order to widen idea and opinion. Research result shows that product which has many ratings and reviews will trigger other buyers to purchase or get that product. The conclusion is that product buying decision may occur because there are some processes before making decision which are: looking for recognition and searching for problems, knowing the needs, collecting information, evaluating alternative, evaluating after buying. In those stages, buying decision on Lazada e-commerce is supported by price, promotion, service, and brand.

  13. Intrinsic and extrinsic motivation as predictors of work effort: The moderating role of achievement goals

    OpenAIRE

    Dysvik, Anders; Kuvaas, Bård

    2013-01-01

    This is the accepted, refereed and final manuscript to the article This research explored the roles of intrinsic and extrinsic motivation and the 2 x 2 model of achievement goals as predictors of increased work effort. A cross-lagged field study was conducted among 1,441 employees from three large Norwegian service organizations across a 10-month time span. The results showed that the relationship between intrinsic motivation and increased work effort was more positive for employees with h...

  14. Joint Efforts Towards European HF Radar Integration

    Science.gov (United States)

    Rubio, A.; Mader, J.; Griffa, A.; Mantovani, C.; Corgnati, L.; Novellino, A.; Schulz-Stellenfleth, J.; Quentin, C.; Wyatt, L.; Ruiz, M. I.; Lorente, P.; Hartnett, M.; Gorringe, P.

    2016-12-01

    During the past two years, significant steps have been made in Europe for achieving the needed accessibility to High Frequency Radar (HFR) data for a pan-European use. Since 2015, EuroGOOS Ocean Observing Task Teams (TT), such as HFR TT, are operational networks of observing platforms. The main goal is on the harmonization of systems requirements, systems design, data quality, improvement and proof of the readiness and standardization of HFR data access and tools. Particular attention is being paid by HFR TT to converge from different projects and programs toward those common objectives. First, JERICO-NEXT (Joint European Research Infrastructure network for Coastal Observatory - Novel European eXpertise for coastal observaTories, H2020 2015 Programme) will contribute on describing the status of the European network, on seeking harmonization through exchange of best practices and standardization, on developing and giving access to quality control procedures and new products, and finally on demonstrating the use of such technology in the general scientific strategy focused by the Coastal Observatory. Then, EMODnet (European Marine Observation and Data Network) Physics started to assemble HF radar metadata and data products within Europe in a uniform way. This long term program is providing a combined array of services and functionalities to users for obtaining free of charge data, meta-data and data products on the physical conditions of European sea basins and oceans. Additionally, the Copernicus Marine Environment Monitoring Service (CMEMS) delivers from 2015 a core information service to any user related to 4 areas of benefits: Maritime Safety, Coastal and Marine Environment, Marine Resources, and Weather, Seasonal Forecasting and Climate activities. INCREASE (Innovation and Networking for the integration of Coastal Radars into EuropeAn marine SErvices - CMEMS Service Evolution 2016) will set the necessary developments towards the integration of existing European

  15. Previous Pedagogical Beliefs of Freshman of Teacher Education

    OpenAIRE

    Rivas Flores, José Ignacio; Pérez Ferra, Miguel; Leite-Méndez, Analía Elizabeth; Quijano López, Rocío; Núñez, Claudio

    2013-01-01

    This paper is part of a research project about how students of teacher education elaborate their professional identity. Through a inquiry on their life stories, the research aims to understand and analyse the experiences of these students along their primary and secondary education, their experiences in university classrooms, and the incidence of these experiences, as well as those generated in schools, in the early years of his teaching career. The project, called “the professional identity ...

  16. Moyamoya disease in a child with previous acute necrotizing encephalopathy

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Taik-Kun; Cha, Sang Hoon; Chung, Kyoo Byung; Kim, Jung Hyuck; Kim, Baek Hyun; Chung, Hwan Hoon [Department of Diagnostic Radiology, Korea University College of Medicine, Ansan Hospital, 516 Kojan-Dong, Ansan City, Kyungki-Do 425-020 (Korea); Eun, Baik-Lin [Department of Pediatrics, Korea University College of Medicine, Seoul (Korea)

    2003-09-01

    A previously healthy 24-day-old boy presented with a 2-day history of fever and had a convulsion on the day of admission. MRI showed abnormal signal in the thalami, caudate nuclei and central white matter. Acute necrotising encephalopathy was diagnosed, other causes having been excluded after biochemical and haematological analysis of blood, urine and CSF. He recovered, but with spastic quadriparesis. At the age of 28 months, he suffered sudden deterioration of consciousness and motor weakness of his right limbs. MRI was consistent with an acute cerebrovascular accident. Angiography showed bilateral middle cerebral artery stenosis or frank occlusion with numerous lenticulostriate collateral vessels consistent with moyamoya disease. (orig.)

  17. MCNP HPGe detector benchmark with previously validated Cyltran model.

    Science.gov (United States)

    Hau, I D; Russ, W R; Bronson, F

    2009-05-01

    An exact copy of the detector model generated for Cyltran was reproduced as an MCNP input file and the detection efficiency was calculated similarly with the methodology used in previous experimental measurements and simulation of a 280 cm(3) HPGe detector. Below 1000 keV the MCNP data correlated to the Cyltran results within 0.5% while above this energy the difference between MCNP and Cyltran increased to about 6% at 4800 keV, depending on the electron cut-off energy.

  18. HEART TRANSPLANTATION IN PATIENTS WITH PREVIOUS OPEN HEART SURGERY

    Directory of Open Access Journals (Sweden)

    R. Sh. Saitgareev

    2016-01-01

    Full Text Available Heart Transplantation (HTx to date remains the most effective and radical method of treatment of patients with end-stage heart failure. The defi cit of donor hearts is forcing to resort increasingly to the use of different longterm mechanical circulatory support systems, including as a «bridge» to the follow-up HTx. According to the ISHLT Registry the number of recipients underwent cardiopulmonary bypass surgery increased from 40% in the period from 2004 to 2008 to 49.6% for the period from 2009 to 2015. HTx performed in repeated patients, on the one hand, involves considerable technical diffi culties and high risks; on the other hand, there is often no alternative medical intervention to HTx, and if not dictated by absolute contradictions the denial of the surgery is equivalent to 100% mortality. This review summarizes the results of a number of published studies aimed at understanding the immediate and late results of HTx in patients, previously underwent open heart surgery. The effect of resternotomy during HTx and that of the specifi c features associated with its implementation in recipients previously operated on open heart, and its effects on the immediate and long-term survival were considered in this review. Results of studies analyzing the risk factors for perioperative complications in repeated recipients were also demonstrated. Separately, HTx risks after implantation of prolonged mechanical circulatory support systems were examined. The literature does not allow to clearly defi ning the impact factor of earlier performed open heart surgery on the course of perioperative period and on the prognosis of survival in recipients who underwent HTx. On the other hand, subject to the regular fl ow of HTx and the perioperative period the risks in this clinical situation are justifi ed as a long-term prognosis of recipients previously conducted open heart surgery and are comparable to those of patients who underwent primary HTx. Studies

  19. A Collaborative Effort to Assess Environmental Health in ...

    Science.gov (United States)

    The Region 3 “Making a Visible Difference in Communities” (MVD) initiative for Southeast Newport News, VA has taken a community-centric, place-based approach to identifying and delivering service to the area’s residents and the city as a whole. Beginning with a CARE (Community Action for a Renewed Environment) Level 1 cooperative agreement (a grant with substantial government involvement and required outputs) in 2011, Region 3 funding helped to establish the Southeast CARE Coalition (“the Coalition”), and quickly formed a bond with the organization. Two years later, Region 3, the US EPA Office of Research and Development (ORD) and the Coalition embarked on a scientific, socio-demographic Regional Sustainable Environmental Science (RESES) research project to assess local pollutant sources and their potential impacts to the community. These efforts helped EPA select Newport News as an MVD community, resulting in an expanded partnership that now includes the City of Newport News. Through this association and the MVD designation, the partners have identified and prioritized environmental and other concerns (e.g., improving air and water quality, adapting to extreme weather, promoting equitable development, improving transportation). Newport News has recently held workshops and training on topics such as environmental health, asthma, weather events, and equitable development, and continues to improve the community’s health, its knowledge of the relevant e

  20. Do Effort and Reward at Work Predict Changes in Cognitive Function? First Longitudinal Results from the Representative German Socio-Economic Panel

    Science.gov (United States)

    Riedel, Natalie; Siegrist, Johannes; Wege, Natalia; Loerbroks, Adrian; Angerer, Peter; Li, Jian

    2017-01-01

    It has been suggested that work characteristics, such as mental demands, job control, and occupational complexity, are prospectively related to cognitive function. However, current evidence on links between psychosocial working conditions and cognitive change over time is inconsistent. In this study, we applied the effort–reward imbalance model that allows to build on previous research on mental demands and to introduce reward-based learning as a principle with beneficial effect on cognitive function. We aimed to investigate whether high effort, high reward, and low over-commitment in 2006 were associated with positive changes in cognitive function in terms of perceptual speed and word fluency (2006–2012), and whether the co-manifestation of high effort and high reward would yield the strongest association. To this end, we used data on 1031 employees who participated in a large and representative study. Multivariate linear regression analyses supported our main hypotheses (separate and combined effects of effort and reward), particularly on changes in perceptual speed, whereas the effects of over-commitment did not reach the level of statistical significance. Our findings extend available knowledge by examining the course of cognitive function over time. If corroborated by further evidence, organization-based measures in the workplace can enrich efforts towards preventing cognitive decline in ageing workforces. PMID:29140258

  1. Do Effort and Reward at Work Predict Changes in Cognitive Function? First Longitudinal Results from the Representative German Socio-Economic Panel

    Directory of Open Access Journals (Sweden)

    Natalie Riedel

    2017-11-01

    Full Text Available It has been suggested that work characteristics, such as mental demands, job control, and occupational complexity, are prospectively related to cognitive function. However, current evidence on links between psychosocial working conditions and cognitive change over time is inconsistent. In this study, we applied the effort–reward imbalance model that allows to build on previous research on mental demands and to introduce reward-based learning as a principle with beneficial effect on cognitive function. We aimed to investigate whether high effort, high reward, and low over-commitment in 2006 were associated with positive changes in cognitive function in terms of perceptual speed and word fluency (2006–2012, and whether the co-manifestation of high effort and high reward would yield the strongest association. To this end, we used data on 1031 employees who participated in a large and representative study. Multivariate linear regression analyses supported our main hypotheses (separate and combined effects of effort and reward, particularly on changes in perceptual speed, whereas the effects of over-commitment did not reach the level of statistical significance. Our findings extend available knowledge by examining the course of cognitive function over time. If corroborated by further evidence, organization-based measures in the workplace can enrich efforts towards preventing cognitive decline in ageing workforces.

  2. Designing Interventions that Last: A Classification of Environmental Behaviors in Relation to the Activities, Costs, and Effort Involved for Adoption and Maintenance

    Science.gov (United States)

    Moore, Harriet E.; Boldero, Jennifer

    2017-01-01

    Policy makers draw on behavioral research to design interventions that promote the voluntary adoption of environmental behavior in societies. Many environmental behaviors will only be effective if they are maintained over the long-term. In the context of climate change and concerns about future water security, behaviors that involve reducing energy consumption and improving water quality must be continued indefinitely to mitigate global warming and preserve scarce resources. Previous reviews of environmental behavior have focused exclusively on factors related to adoption. This review investigates the factors that influence both adoption and maintenance, and presents a classification of environmental behaviors in terms of the activities, costs, and effort required for both adoption and maintenance. Three categories of behavior are suggested. One-off behaviors involve performing an activity once, such as purchasing an energy efficient washing machine, or signing a petition. Continuous behaviors involve the performance of the same set of behaviors for adoption and for maintenance, such as curbside recycling. Dynamic behaviors involve the performance of different behaviors for adoption and maintenance, such as revegetation. Behaviors can also be classified into four categories related to cost and effort: those that involve little cost and effort for adoption and maintenance, those that involve moderate cost and effort for adoption and maintenance, those that involve a high cost or effort for adoption and less for maintenance, and those that involve less cost or effort for adoption and a higher amount for maintenance. In order to design interventions that last, policy makers should consider the factors that influence the maintenance as well as the adoption of environmental behaviors. PMID:29163265

  3. Nicotine increases impulsivity and decreases willingness to exert cognitive effort despite improving attention in "slacker" rats: insights into cholinergic regulation of cost/benefit decision making.

    Science.gov (United States)

    Hosking, Jay G; Lam, Fred C W; Winstanley, Catharine A

    2014-01-01

    Successful decision making in our daily lives requires weighing an option's costs against its associated benefits. The neuromodulator acetylcholine underlies both the etiology and treatment of a number of illnesses in which decision making is perturbed, including Alzheimer's disease, attention-deficit/hyperactivity disorder, and schizophrenia. Nicotine acts on the cholinergic system and has been touted as a cognitive enhancer by both smokers and some researchers for its attention-boosting effects; however, it is unclear whether treatments that have a beneficial effect on attention would also have a beneficial effect on decision making. Here we utilize the rodent Cognitive Effort Task (rCET), wherein animals can choose to allocate greater visuospatial attention for a greater reward, to examine cholinergic contributions to both attentional performance and choice based on attentional demand. Following the establishment of baseline behavior, four drug challenges were administered: nicotine, mecamylamine, scopolamine, and oxotremorine (saline plus three doses for each). As per previous rCET studies, animals were divided by their baseline preferences, with "worker" rats choosing high-effort/high-reward options more than their "slacker" counterparts. Nicotine caused slackers to choose even fewer high-effort trials than at baseline, but had no effect on workers' choice. Despite slackers' decreased willingness to expend effort, nicotine improved their attentional performance on the task. Nicotine also increased measures of motor impulsivity in all animals. In contrast, scopolamine decreased animals' choice of high-effort trials, especially for workers, while oxotremorine decreased motor impulsivity for all animals. In sum, the cholinergic system appears to contribute to decision making, and in part these contributions can be understood as a function of individual differences. While nicotine has been considered as a cognitive enhancer, these data suggest that its modest

  4. Nicotine increases impulsivity and decreases willingness to exert cognitive effort despite improving attention in "slacker" rats: insights into cholinergic regulation of cost/benefit decision making.

    Directory of Open Access Journals (Sweden)

    Jay G Hosking

    Full Text Available Successful decision making in our daily lives requires weighing an option's costs against its associated benefits. The neuromodulator acetylcholine underlies both the etiology and treatment of a number of illnesses in which decision making is perturbed, including Alzheimer's disease, attention-deficit/hyperactivity disorder, and schizophrenia. Nicotine acts on the cholinergic system and has been touted as a cognitive enhancer by both smokers and some researchers for its attention-boosting effects; however, it is unclear whether treatments that have a beneficial effect on attention would also have a beneficial effect on decision making. Here we utilize the rodent Cognitive Effort Task (rCET, wherein animals can choose to allocate greater visuospatial attention for a greater reward, to examine cholinergic contributions to both attentional performance and choice based on attentional demand. Following the establishment of baseline behavior, four drug challenges were administered: nicotine, mecamylamine, scopolamine, and oxotremorine (saline plus three doses for each. As per previous rCET studies, animals were divided by their baseline preferences, with "worker" rats choosing high-effort/high-reward options more than their "slacker" counterparts. Nicotine caused slackers to choose even fewer high-effort trials than at baseline, but had no effect on workers' choice. Despite slackers' decreased willingness to expend effort, nicotine improved their attentional performance on the task. Nicotine also increased measures of motor impulsivity in all animals. In contrast, scopolamine decreased animals' choice of high-effort trials, especially for workers, while oxotremorine decreased motor impulsivity for all animals. In sum, the cholinergic system appears to contribute to decision making, and in part these contributions can be understood as a function of individual differences. While nicotine has been considered as a cognitive enhancer, these data suggest

  5. Milky Way Past Was More Turbulent Than Previously Known

    Science.gov (United States)

    2004-04-01

    Results of 1001 observing nights shed new light on our Galaxy [1] Summary A team of astronomers from Denmark, Switzerland and Sweden [2] has achieved a major breakthrough in our understanding of the Milky Way, the galaxy in which we live. After more than 1,000 nights of observations spread over 15 years, they have determined the spatial motions of more than 14,000 solar-like stars residing in the neighbourhood of the Sun. For the first time, the changing dynamics of the Milky Way since its birth can now be studied in detail and with a stellar sample sufficiently large to allow a sound analysis. The astronomers find that our home galaxy has led a much more turbulent and chaotic life than previously assumed. PR Photo 10a/04: Distribution on the sky of the observed stars. PR Photo 10b/04: Stars in the solar neigbourhood and the Milky Way galaxy (artist's view). PR Video Clip 04/04: The motions of the observed stars during the past 250 million years. Unknown history Home is the place we know best. But not so in the Milky Way - the galaxy in which we live. Our knowledge of our nearest stellar neighbours has long been seriously incomplete and - worse - skewed by prejudice concerning their behaviour. Stars were generally selected for observation because they were thought to be "interesting" in some sense, not because they were typical. This has resulted in a biased view of the evolution of our Galaxy. The Milky Way started out just after the Big Bang as one or more diffuse blobs of gas of almost pure hydrogen and helium. With time, it assembled into the flattened spiral galaxy which we inhabit today. Meanwhile, generation after generation of stars were formed, including our Sun some 4,700 million years ago. But how did all this really happen? Was it a rapid process? Was it violent or calm? When were all the heavier elements formed? How did the Milky Way change its composition and shape with time? Answers to these and many other questions are 'hot' topics for the

  6. Deliberate practice theory: perceived relevance, effort, and inherent enjoyment of music practice: study II.

    Science.gov (United States)

    Hyllegard, Randy; Bories, Tamara L

    2009-10-01

    This study, based on the theory of deliberate practice, examined the practice relevance, effort, and inherent enjoyment aspects of the theory. 25 college undergraduates practiced playing a melody on an electronic keyboard for three 20-min. practice sessions. Following each session, the perceived relevance of the practice for improving performance of the melody, the effort needed to learn the melody, and the inherent enjoyment of the practice were each rated on 10-point scales. Findings were consistent with theory and similar to previous studies also involving music practice and other tasks.

  7. "Efforts to Reprioritise the Agenda" in China: British American Tobacco's Efforts to Influence Public Policy on Secondhand Smoke in China.

    Directory of Open Access Journals (Sweden)

    Monique E Muggli

    2008-12-01

    Full Text Available Each year, 540 million Chinese are exposed to secondhand smoke (SHS, resulting in more than 100,000 deaths. Smoke-free policies have been demonstrated to decrease overall cigarette consumption, encourage smokers to quit, and protect the health of nonsmokers. However, restrictions on smoking in China remain limited and ineffective. Internal tobacco industry documents show that transnational tobacco companies (TTCs have pursued a multifaceted strategy for undermining the adoption of restrictions on smoking in many countries.To understand company activities in China related to SHS, we analyzed British American Tobacco's (BAT's internal corporate documents produced in response to litigation against the major cigarette manufacturers to understand company activities in China related to SHS. BAT has carried out an extensive strategy to undermine the health policy agenda on SHS in China by attempting to divert public attention from SHS issues towards liver disease prevention, pushing the so-called "resocialisation of smoking" accommodation principles, and providing "training" for industry, public officials, and the media based on BAT's corporate agenda that SHS is an insignificant contributor to the larger issue of air pollution.The public health community in China should be aware of the tactics previously used by TTCs, including efforts by the tobacco industry to co-opt prominent Chinese benevolent organizations, when seeking to enact stronger restrictions on smoking in public places.

  8. "Efforts to Reprioritise the Agenda" in China: British American Tobacco's Efforts to Influence Public Policy on Secondhand Smoke in China.

    Science.gov (United States)

    Muggli, Monique E; Lee, Kelley; Gan, Quan; Ebbert, Jon O; Hurt, Richard D

    2008-12-23

    Each year, 540 million Chinese are exposed to secondhand smoke (SHS), resulting in more than 100,000 deaths. Smoke-free policies have been demonstrated to decrease overall cigarette consumption, encourage smokers to quit, and protect the health of nonsmokers. However, restrictions on smoking in China remain limited and ineffective. Internal tobacco industry documents show that transnational tobacco companies (TTCs) have pursued a multifaceted strategy for undermining the adoption of restrictions on smoking in many countries. To understand company activities in China related to SHS, we analyzed British American Tobacco's (BAT's) internal corporate documents produced in response to litigation against the major cigarette manufacturers to understand company activities in China related to SHS. BAT has carried out an extensive strategy to undermine the health policy agenda on SHS in China by attempting to divert public attention from SHS issues towards liver disease prevention, pushing the so-called "resocialisation of smoking" accommodation principles, and providing "training" for industry, public officials, and the media based on BAT's corporate agenda that SHS is an insignificant contributor to the larger issue of air pollution. The public health community in China should be aware of the tactics previously used by TTCs, including efforts by the tobacco industry to co-opt prominent Chinese benevolent organizations, when seeking to enact stronger restrictions on smoking in public places.

  9. Proteomics Analysis Reveals Previously Uncharacterized Virulence Factors in Vibrio proteolyticus

    Directory of Open Access Journals (Sweden)

    Ann Ray

    2016-07-01

    Full Text Available Members of the genus Vibrio include many pathogens of humans and marine animals that share genetic information via horizontal gene transfer. Hence, the Vibrio pan-genome carries the potential to establish new pathogenic strains by sharing virulence determinants, many of which have yet to be characterized. Here, we investigated the virulence properties of Vibrio proteolyticus, a Gram-negative marine bacterium previously identified as part of the Vibrio consortium isolated from diseased corals. We found that V. proteolyticus causes actin cytoskeleton rearrangements followed by cell lysis in HeLa cells in a contact-independent manner. In search of the responsible virulence factor involved, we determined the V. proteolyticus secretome. This proteomics approach revealed various putative virulence factors, including active type VI secretion systems and effectors with virulence toxin domains; however, these type VI secretion systems were not responsible for the observed cytotoxic effects. Further examination of the V. proteolyticus secretome led us to hypothesize and subsequently demonstrate that a secreted hemolysin, belonging to a previously uncharacterized clan of the leukocidin superfamily, was the toxin responsible for the V. proteolyticus-mediated cytotoxicity in both HeLa cells and macrophages. Clearly, there remains an armory of yet-to-be-discovered virulence factors in the Vibrio pan-genome that will undoubtedly provide a wealth of knowledge on how a pathogen can manipulate host cells.

  10. Incidence of Acneform Lesions in Previously Chemically Damaged Persons-2004

    Directory of Open Access Journals (Sweden)

    N Dabiri

    2008-04-01

    Full Text Available ABSTRACT: Introduction & Objective: Chemical gas weapons especially nitrogen mustard which was used in Iraq-Iran war against Iranian troops have several harmful effects on skin. Some other chemical agents also can cause acne form lesions on skin. The purpose of this study was to compare the incidence of acneform in previously chemically damaged soldiers and non chemically damaged persons. Materials & Methods: In this descriptive and analytical study, 180 chemically damaged soldiers, who have been referred to dermatology clinic between 2000 – 2004, and forty non-chemically damaged people, were chosen randomly and examined for acneform lesions. SPSS software was used for statistic analysis of the data. Results: The mean age of the experimental group was 37.5 ± 5.2 and that of the control group was 38.7 ± 5.9 years. The mean percentage of chemical damage in cases was 31 percent and the time after the chemical damage was 15.2 ± 1.1 years. Ninety seven cases (53.9 percent of the subjects and 19 people (47.5 percent of the control group had some degree of acne. No significant correlation was found in incidence, degree of lesions, site of lesions and age of subjects between two groups. No significant correlation was noted between percentage of chemical damage and incidence and degree of lesions in case group. Conclusion: Incidence of acneform lesions among previously chemically injured peoples was not higher than the normal cases.

  11. Relationship of deer and moose populations to previous winters' snow

    Science.gov (United States)

    Mech, L.D.; McRoberts, R.E.; Peterson, R.O.; Page, R.E.

    1987-01-01

    (1) Linear regression was used to relate snow accumulation during single and consecutive winters with white-tailed deer (Odocoileus virginianus) fawn:doe ratios, mosse (Alces alces) twinning rates and calf:cow ratios, and annual changes in deer and moose populations. Significant relationships were found between snow accumulation during individual winters and these dependent variables during the following year. However, the strongest relationships were between the dependent variables and the sums of the snow accumulations over the previous three winters. The percentage of the variability explained was 36 to 51. (2) Significant relationships were also found between winter vulnerability of moose calves and the sum of the snow accumulations in the current, and up to seven previous, winters, with about 49% of the variability explained. (3) No relationship was found between wolf numbers and the above dependent variables. (4) These relationships imply that winter influences on maternal nutrition can accumulate for several years and that this cumulative effect strongly determines fecundity and/or calf and fawn survivability. Although wolf (Canis lupus L.) predation is the main direct mortality agent on fawns and calves, wolf density itself appears to be secondary to winter weather in influencing the deer and moose populations.

  12. Kidnapping Detection and Recognition in Previous Unknown Environment

    Directory of Open Access Journals (Sweden)

    Yang Tian

    2017-01-01

    Full Text Available An unaware event referred to as kidnapping makes the estimation result of localization incorrect. In a previous unknown environment, incorrect localization result causes incorrect mapping result in Simultaneous Localization and Mapping (SLAM by kidnapping. In this situation, the explored area and unexplored area are divided to make the kidnapping recovery difficult. To provide sufficient information on kidnapping, a framework to judge whether kidnapping has occurred and to identify the type of kidnapping with filter-based SLAM is proposed. The framework is called double kidnapping detection and recognition (DKDR by performing two checks before and after the “update” process with different metrics in real time. To explain one of the principles of DKDR, we describe a property of filter-based SLAM that corrects the mapping result of the environment using the current observations after the “update” process. Two classical filter-based SLAM algorithms, Extend Kalman Filter (EKF SLAM and Particle Filter (PF SLAM, are modified to show that DKDR can be simply and widely applied in existing filter-based SLAM algorithms. Furthermore, a technique to determine the adapted thresholds of metrics in real time without previous data is presented. Both simulated and experimental results demonstrate the validity and accuracy of the proposed method.

  13. [ANTITHROMBOTIC MEDICATION IN PREGNANT WOMEN WITH PREVIOUS INTRAUTERINE GROWTH RESTRICTION].

    Science.gov (United States)

    Neykova, K; Dimitrova, V; Dimitrov, R; Vakrilova, L

    2016-01-01

    To analyze pregnancy outcome in patients who were on antithrombotic medication (AM) because of previous pregnancy with fetal intrauterine growth restriction (IUGR). The studied group (SG) included 21 pregnancies in 15 women with history of previous IUGR. The patients were on low dose aspirin (LDA) and/or low molecular weight heparin (LMWH). Pregnancy outcome was compared to the one in two more groups: 1) primary group (PG) including the previous 15 pregnancies with IUGR of the same women; 2) control group (CG) including 45 pregnancies of women matched for parity with the ones in the SG, with no history of IUGR and without medication. The SG, PG and CG were compared for the following: mean gestational age (g.a.) at birth, mean birth weight (BW), proportion of cases with early preeclampsia (PE), IUGR (total, moderate, and severe), intrauterine fetal death (IUFD), neonatal death (NND), admission to NICU, cesarean section (CS) because of chronic or acute fetal distress (FD) related to IUGR, PE or placental abruption. Student's t-test was applied to assess differences between the groups. P values < 0.05 were considered statistically significant. The differences between the SG and the PG regarding mean g. a. at delivery (33.7 and 29.8 w.g. respectively) and the proportion of babies admitted to NICU (66.7% vs. 71.4%) were not statistically significant. The mean BW in the SG (2114,7 g.) was significantly higher than in the PG (1090.8 g.). In the SG compared with the PG there were significantly less cases of IUFD (14.3% and 53.3% respectively), early PE (9.5% vs. 46.7%) moderate and severe IUGR (10.5% and 36.8% vs. 41.7% and 58.3%). Neonatal mortality in the SG (5.6%) was significantly lower than in the PG (57.1%), The proportion of CS for FD was not significantly different--53.3% in the SG and 57.1% in the PG. On the other hand, comparison between the SG and the CG demonstrated significantly lower g.a. at delivery in the SG (33.7 vs. 38 w.g.) an lower BW (2114 vs. 3094 g

  14. DARPA-funded efforts in the development of novel brain-computer interface technologies.

    Science.gov (United States)

    Miranda, Robbin A; Casebeer, William D; Hein, Amy M; Judy, Jack W; Krotkov, Eric P; Laabs, Tracy L; Manzo, Justin E; Pankratz, Kent G; Pratt, Gill A; Sanchez, Justin C; Weber, Douglas J; Wheeler, Tracey L; Ling, Geoffrey S F

    2015-04-15

    The Defense Advanced Research Projects Agency (DARPA) has funded innovative scientific research and technology developments in the field of brain-computer interfaces (BCI) since the 1970s. This review highlights some of DARPA's major advances in the field of BCI, particularly those made in recent years. Two broad categories of DARPA programs are presented with respect to the ultimate goals of supporting the nation's warfighters: (1) BCI efforts aimed at restoring neural and/or behavioral function, and (2) BCI efforts aimed at improving human training and performance. The programs discussed are synergistic and complementary to one another, and, moreover, promote interdisciplinary collaborations among researchers, engineers, and clinicians. Finally, this review includes a summary of some of the remaining challenges for the field of BCI, as well as the goals of new DARPA efforts in this domain. Copyright © 2014 The Authors. Published by Elsevier B.V. All rights reserved.

  15. Life-history traits in an evergreen Mediterranean oak respond differentially to previous experimental environments

    Directory of Open Access Journals (Sweden)

    J. M. Rey Benayas

    2008-06-01

    Full Text Available Living organisms respond both to current and previous environments, which can have important consequences on population dynamics. However, there is little experimental evidence based on long-term field studies of the effects of previous environments on the performance of individuals. We tested the hypothesis that trees that establish under different environmental conditions perform differently under similar post-establishment conditions. We used the slow-growing, evergreen Mediterranean oak Quercus ilex subsp. rotundifolia as target species. We analyzed the effects of previous environments, competition effects and tradeoffs among life-history traits (survival, growth, and reproduction. We enhanced seedling establishment for three years by reducing abiotic environmental harshness by means of summer irrigation and artificial shading in 12 experimental plots, while four plots remained as controls. Then these treatments were interrupted for ten years. Seedlings under ameliorated environmental conditions survived and grew faster during early establishment. During the post-management period, previous treatments 1 did not have any effect on survival, 2 experienced a slower above-ground growth, 3 decreased root biomass as indicated from reflectivity of Ground Penetration Radar, 4 increased acorn production mostly through a greater canopy volume and 5 increased acorn production effort. The trees exhibited a combination of effects related to acclimation for coping with abiotic stress and effects of intra-specific competition. In accordance with our hypothesis, tree performance overall depended on previous environmental conditions, and the response was different for different life-history traits. We recommend early management because it increased plot cover, shortened the time to attain sexual maturity and increased the amount of acorn production. Plots such as those assessed in this study may act as sources of propagules in deforested

  16. Age, training, and previous experience predict race performance in long-distance inline skaters, not anthropometry.

    Science.gov (United States)

    Knechtle, Beat; Knechtle, Patrizia; Rüst, Christoph Alexander; Rosemann, Thomas; Lepers, Romuald

    2012-02-01

    The association of characteristics of anthropometry, training, and previous experience with race time in 84 recreational, long-distance, inline skaters at the longest inline marathon in Europe (111 km), the Inline One-eleven in Switzerland, was investigated to identify predictor variables for performance. Age, duration per training unit, and personal best time were the only three variables related to race time in a multiple regression, while none of the 16 anthropometric variables were related. Anthropometric characteristics seem to be of no importance for a fast race time in a long-distance inline skating race in contrast to training volume and previous experience, when controlled with covariates. Improving performance in a long-distance inline skating race might be related to a high training volume and previous race experience. Also, doing such a race requires a parallel psychological effort, mental stamina, focus, and persistence. This may be reflected in the preparation and training for the event. Future studies should investigate what motivates these athletes to train and compete.

  17. New energy carriers in vehicles and their impact on confined infrastructures Overview of previous research and research needs

    OpenAIRE

    Salvi , Olivier; Lonnermark , Anders; Ingason , Haukur; Truchot , Benjamin; Leucker , Roland; Amberg , Félix; Molenaar , Dirk-Jan; Hejny , Horst

    2010-01-01

    International audience; The global warming debate forces the vehicle industry to come up with new environmentally friendly solutions. In 10 years time, or even faster depending on the pressure from different governments in particular in Europe, vehicles will not only use gasoline, diesel and LPG, but also CNG, Hydrogen, ethanol, DME and other bio-fuels, as well as batteries and fuel cells. This quick development and the diversity of new energy carriers can jeopardize the safety in underground...

  18. Deepwater Gulf of Mexico more profitable than previously thought

    International Nuclear Information System (INIS)

    Craig, M.J.K.; Hyde, S.T.

    1997-01-01

    Economic evaluations and recent experience show that the deepwater Gulf of Mexico (GOM) is much more profitable than previously thought. Four factors contributing to the changed viewpoint are: First, deepwater reservoirs have proved to have excellent productive capacity, distribution, and continuity when compared to correlative-age shelf deltaic sands. Second, improved technologies and lower perceived risks have lowered the cost of floating production systems (FPSs). Third, projects now get on-line quicker. Fourth, a collection of other important factors are: Reduced geologic risk and associated high success rates for deepwater GOM wells due primarily to improved seismic imaging and processing tools (3D, AVO, etc.); absence of any political risk in the deepwater GOM (common overseas, and very significant in some international areas); and positive impact of deepwater federal royalty relief. This article uses hypothetical reserve distributions and price forecasts to illustrate indicative economics of deepwater prospects. Economics of Shell Oil Co.'s three deepwater projects are also discussed

  19. Corneal perforation after conductive keratoplasty with previous refractive surgery.

    Science.gov (United States)

    Kymionis, George D; Titze, Patrik; Markomanolakis, Marinos M; Aslanides, Ioannis M; Pallikaris, Ioannis G

    2003-12-01

    A 56-year-old woman had conductive keratoplasty (CK) for residual hyperopia and astigmatism. Three years before the procedure, the patient had arcuate keratotomy, followed by laser in situ keratomileusis 2 years later for high astigmatism correction in both eyes. During CK, a corneal perforation occurred in the right eye; during the postoperative examination, an iris perforation and anterior subcapsule opacification were seen beneath the perforation site. The perforation was managed with a bandage contact lens and an antibiotic-steroid ointment; it had a negative Seidel sign by the third day. The surgery in the left eye was uneventful. Three months after the procedure, the uncorrected visual acuity was 20/32 and the best corrected visual acuity 20/20 in both eyes with a significant improvement in corneal topography. Care must be taken to prevent CK-treated spots from coinciding with areas in the corneal stroma that might have been altered by previous refractive procedures.

  20. The long-term consequences of previous hyperthyroidism

    DEFF Research Database (Denmark)

    Hjelm Brandt Kristensen, Frans

    2015-01-01

    Thyroid hormones affect every cell in the human body, and the cardiovascular changes associated with increased levels of thyroid hormones are especially well described. As an example, short-term hyperthyroidism has positive chronotropic and inotropic effects on the heart, leading to a hyperdynamic...... with CVD, LD and DM both before and after the diagnosis of hyperthyroidism. Although the design used does not allow a stringent distinction between cause and effect, the findings indicate a possible direct association between hyperthyroidism and these morbidities, or vice versa....... vascular state. While it is biologically plausible that these changes may induce long-term consequences, the insight into morbidity as well as mortality in patients with previous hyperthyroidism is limited. The reasons for this are a combination of inadequately powered studies, varying definitions...

  1. Is Previous Respiratory Disease a Risk Factor for Lung Cancer?

    Science.gov (United States)

    Denholm, Rachel; Schüz, Joachim; Straif, Kurt; Stücker, Isabelle; Jöckel, Karl-Heinz; Brenner, Darren R.; De Matteis, Sara; Boffetta, Paolo; Guida, Florence; Brüske, Irene; Wichmann, Heinz-Erich; Landi, Maria Teresa; Caporaso, Neil; Siemiatycki, Jack; Ahrens, Wolfgang; Pohlabeln, Hermann; Zaridze, David; Field, John K.; McLaughlin, John; Demers, Paul; Szeszenia-Dabrowska, Neonila; Lissowska, Jolanta; Rudnai, Peter; Fabianova, Eleonora; Dumitru, Rodica Stanescu; Bencko, Vladimir; Foretova, Lenka; Janout, Vladimir; Kendzia, Benjamin; Peters, Susan; Behrens, Thomas; Vermeulen, Roel; Brüning, Thomas; Kromhout, Hans

    2014-01-01

    Rationale: Previous respiratory diseases have been associated with increased risk of lung cancer. Respiratory conditions often co-occur and few studies have investigated multiple conditions simultaneously. Objectives: Investigate lung cancer risk associated with chronic bronchitis, emphysema, tuberculosis, pneumonia, and asthma. Methods: The SYNERGY project pooled information on previous respiratory diseases from 12,739 case subjects and 14,945 control subjects from 7 case–control studies conducted in Europe and Canada. Multivariate logistic regression models were used to investigate the relationship between individual diseases adjusting for co-occurring conditions, and patterns of respiratory disease diagnoses and lung cancer. Analyses were stratified by sex, and adjusted for age, center, ever-employed in a high-risk occupation, education, smoking status, cigarette pack-years, and time since quitting smoking. Measurements and Main Results: Chronic bronchitis and emphysema were positively associated with lung cancer, after accounting for other respiratory diseases and smoking (e.g., in men: odds ratio [OR], 1.33; 95% confidence interval [CI], 1.20–1.48 and OR, 1.50; 95% CI, 1.21–1.87, respectively). A positive relationship was observed between lung cancer and pneumonia diagnosed 2 years or less before lung cancer (OR, 3.31; 95% CI, 2.33–4.70 for men), but not longer. Co-occurrence of chronic bronchitis and emphysema and/or pneumonia had a stronger positive association with lung cancer than chronic bronchitis “only.” Asthma had an inverse association with lung cancer, the association being stronger with an asthma diagnosis 5 years or more before lung cancer compared with shorter. Conclusions: Findings from this large international case–control consortium indicate that after accounting for co-occurring respiratory diseases, chronic bronchitis and emphysema continue to have a positive association with lung cancer. PMID:25054566

  2. Twelve previously unknown phage genera are ubiquitous in global oceans.

    Science.gov (United States)

    Holmfeldt, Karin; Solonenko, Natalie; Shah, Manesh; Corrier, Kristen; Riemann, Lasse; Verberkmoes, Nathan C; Sullivan, Matthew B

    2013-07-30

    Viruses are fundamental to ecosystems ranging from oceans to humans, yet our ability to study them is bottlenecked by the lack of ecologically relevant isolates, resulting in "unknowns" dominating culture-independent surveys. Here we present genomes from 31 phages infecting multiple strains of the aquatic bacterium Cellulophaga baltica (Bacteroidetes) to provide data for an underrepresented and environmentally abundant bacterial lineage. Comparative genomics delineated 12 phage groups that (i) each represent a new genus, and (ii) represent one novel and four well-known viral families. This diversity contrasts the few well-studied marine phage systems, but parallels the diversity of phages infecting human-associated bacteria. Although all 12 Cellulophaga phages represent new genera, the podoviruses and icosahedral, nontailed ssDNA phages were exceptional, with genomes up to twice as large as those previously observed for each phage type. Structural novelty was also substantial, requiring experimental phage proteomics to identify 83% of the structural proteins. The presence of uncommon nucleotide metabolism genes in four genera likely underscores the importance of scavenging nutrient-rich molecules as previously seen for phages in marine environments. Metagenomic recruitment analyses suggest that these particular Cellulophaga phages are rare and may represent a first glimpse into the phage side of the rare biosphere. However, these analyses also revealed that these phage genera are widespread, occurring in 94% of 137 investigated metagenomes. Together, this diverse and novel collection of phages identifies a small but ubiquitous fraction of unknown marine viral diversity and provides numerous environmentally relevant phage-host systems for experimental hypothesis testing.

  3. Typing DNA profiles from previously enhanced fingerprints using direct PCR.

    Science.gov (United States)

    Templeton, Jennifer E L; Taylor, Duncan; Handt, Oliva; Linacre, Adrian

    2017-07-01

    Fingermarks are a source of human identification both through the ridge patterns and DNA profiling. Typing nuclear STR DNA markers from previously enhanced fingermarks provides an alternative method of utilising the limited fingermark deposit that can be left behind during a criminal act. Dusting with fingerprint powders is a standard method used in classical fingermark enhancement and can affect DNA data. The ability to generate informative DNA profiles from powdered fingerprints using direct PCR swabs was investigated. Direct PCR was used as the opportunity to generate usable DNA profiles after performing any of the standard DNA extraction processes is minimal. Omitting the extraction step will, for many samples, be the key to success if there is limited sample DNA. DNA profiles were generated by direct PCR from 160 fingermarks after treatment with one of the following dactyloscopic fingerprint powders: white hadonite; silver aluminium; HiFi Volcano silk black; or black magnetic fingerprint powder. This was achieved by a combination of an optimised double-swabbing technique and swab media, omission of the extraction step to minimise loss of critical low-template DNA, and additional AmpliTaq Gold ® DNA polymerase to boost the PCR. Ninety eight out of 160 samples (61%) were considered 'up-loadable' to the Australian National Criminal Investigation DNA Database (NCIDD). The method described required a minimum of working steps, equipment and reagents, and was completed within 4h. Direct PCR allows the generation of DNA profiles from enhanced prints without the need to increase PCR cycle numbers beyond manufacturer's recommendations. Particular emphasis was placed on preventing contamination by applying strict protocols and avoiding the use of previously used fingerprint brushes. Based on this extensive survey, the data provided indicate minimal effects of any of these four powders on the chance of obtaining DNA profiles from enhanced fingermarks. Copyright © 2017

  4. Impact of stimulus-related factors and hearing impairment on listening effort as indicated by pupil dilation

    DEFF Research Database (Denmark)

    Ohlenforst, Barbara; Zekveld, Adriana A.; Lunner, Thomas

    2017-01-01

    Previous research has reported effects of masker type and signal-to-noise ratio (SNR) on listening effort, as indicated by the peak pupil dilation (PPD) relative to baseline during speech recognition. At about 50% correct sentence recognition performance, increasing SNRs generally results...... in declining PPDs, indicating reduced effort. However, the decline in PPD over SNRs has been observed to be less pronounced for hearing-impaired (HI) compared to normal-hearing (NH) listeners. The presence of a competing talker during speech recognition generally resulted in larger PPDs as compared......-talker masker) on the PPD during speech perception. Twenty-five HI and 32 age-matched NH participants listened to sentences across a broad range of SNRs, masked with speech from a single talker (-25 dB to +15 dB SNR) or with stationary noise (-12 dB to +16 dB). Correct sentence recognition scores and pupil...

  5. Basic research for environmental restoration

    International Nuclear Information System (INIS)

    1990-12-01

    The Department of Energy (DOE) is in the midst of a major environmental restoration effort to reduce the health and environmental risks resulting from past waste management and disposal practices at DOE sites. This report describes research needs in environmental restoration and complements a previously published document, DOE/ER-0419, Evaluation of Mid-to-Long Term Basic Research for Environmental Restoration. Basic research needs have been grouped into five major categories patterned after those identified in DOE/ER-0419: (1) environmental transport and transformations; (2) advanced sampling, characterization, and monitoring methods; (3) new remediation technologies; (4) performance assessment; and (5) health and environmental effects. In addition to basic research, this document deals with education and training needs for environmental restoration. 2 figs., 6 tabs

  6. Basic research for environmental restoration

    Energy Technology Data Exchange (ETDEWEB)

    1990-12-01

    The Department of Energy (DOE) is in the midst of a major environmental restoration effort to reduce the health and environmental risks resulting from past waste management and disposal practices at DOE sites. This report describes research needs in environmental restoration and complements a previously published document, DOE/ER-0419, Evaluation of Mid-to-Long Term Basic Research for Environmental Restoration. Basic research needs have been grouped into five major categories patterned after those identified in DOE/ER-0419: (1) environmental transport and transformations; (2) advanced sampling, characterization, and monitoring methods; (3) new remediation technologies; (4) performance assessment; and (5) health and environmental effects. In addition to basic research, this document deals with education and training needs for environmental restoration. 2 figs., 6 tabs.

  7. Supercomputer and cluster performance modeling and analysis efforts:2004-2006.

    Energy Technology Data Exchange (ETDEWEB)

    Sturtevant, Judith E.; Ganti, Anand; Meyer, Harold (Hal) Edward; Stevenson, Joel O.; Benner, Robert E., Jr. (.,; .); Goudy, Susan Phelps; Doerfler, Douglas W.; Domino, Stefan Paul; Taylor, Mark A.; Malins, Robert Joseph; Scott, Ryan T.; Barnette, Daniel Wayne; Rajan, Mahesh; Ang, James Alfred; Black, Amalia Rebecca; Laub, Thomas William; Vaughan, Courtenay Thomas; Franke, Brian Claude

    2007-02-01

    This report describes efforts by the Performance Modeling and Analysis Team to investigate performance characteristics of Sandia's engineering and scientific applications on the ASC capability and advanced architecture supercomputers, and Sandia's capacity Linux clusters. Efforts to model various aspects of these computers are also discussed. The goals of these efforts are to quantify and compare Sandia's supercomputer and cluster performance characteristics; to reveal strengths and weaknesses in such systems; and to predict performance characteristics of, and provide guidelines for, future acquisitions and follow-on systems. Described herein are the results obtained from running benchmarks and applications to extract performance characteristics and comparisons, as well as modeling efforts, obtained during the time period 2004-2006. The format of the report, with hypertext links to numerous additional documents, purposefully minimizes the document size needed to disseminate the extensive results from our research.

  8. Heart rate variability reflects self-regulatory strength, effort, and fatigue.

    Science.gov (United States)

    Segerstrom, Suzanne C; Nes, Lise Solberg

    2007-03-01

    Experimental research reliably demonstrates that self-regulatory deficits are a consequence of prior self-regulatory effort. However, in naturalistic settings, although people know that they are sometimes vulnerable to saying, eating, or doing the wrong thing, they cannot accurately gauge their capacity to self-regulate at any given time. Because self-regulation and autonomic regulation colocalize in the brain, an autonomic measure, heart rate variability (HRV), could provide an index of self-regulatory strength and activity. During an experimental manipulation of self-regulation (eating carrots or cookies), HRV was elevated during high self-regulatory effort (eat carrots, resist cookies) compared with low self-regulatory effort (eat cookies, resist carrots). The experimental manipulation and higher HRV at baseline independently predicted persistence at a subsequent anagram task. HRV appears to index self-regulatory strength and effort, making it possible to study these phenomena in the field as well as the lab.

  9. Wives without husbands: gendered vulnerability to sexually transmitted infections among previously married women in India.

    Science.gov (United States)

    Walters, Kimberly; Dandona, Rakhi; Walters, Lawrence C; Lakshmi, Vemu; Dandona, Lalit; Schneider, John A

    2012-01-01

    Using population-based and family structural data from a high HIV-prevalence district of Southern India, this paper considers four suggested social scenarios used to explain the positive correlation between HIV prevalence and previously married status among Indian women: (1) infection from and then bereavement of an infected husband; (2) abandonment after husbands learn of their wives' HIV status; (3) economic instability after becoming previously married, leading women to seek financial support through male partners; and (4) the social status of being previously married exposing women to sexual harassment and predation. By also considering seroprevalence of two other common sexually transmitted infections (STIs), herpes and syphilis, in a combined variable with HIV, we limit the likelihood of the first two scenarios accounting for the greater part of this correlation. Through a nuanced analysis of household residences patterns (family structure), standard of living, and education, we also limit the probability that scenario three explains a greater portion of the correlation. Scenario four emerges as the most likely explanation for this correlation, recognizing that other scenarios are also possible. Further, the interdisciplinary literature on the social position of previously married women in India strongly supports the suggestion that, as a population, previously married women are sexually vulnerable in India. Previously married status as an STI risk factor requires further biosocial research and warrants concentrated public health attention.

  10. Bodily Effort Enhances Learning and Metacognition: Investigating the Relation Between Physical Effort and Cognition Using Dual-Process Models of Embodiment.

    Science.gov (United States)

    Skulmowski, Alexander; Rey, Günter Daniel

    2017-01-01

    Recent embodiment research revealed that cognitive processes can be influenced by bodily cues. Some of these cues were found to elicit disparate effects on cognition. For instance, weight sensations can inhibit problem-solving performance, but were shown to increase judgments regarding recall probability (judgments of learning; JOLs) in memory tasks. We investigated the effects of physical effort on learning and metacognition by conducting two studies in which we varied whether a backpack was worn or not while 20 nouns were to be learned. Participants entered a JOL for each word and completed a recall test. Experiment 1 ( N = 18) revealed that exerting physical effort by wearing a backpack led to higher JOLs for easy nouns, without a notable effect on difficult nouns. Participants who wore a backpack reached higher recall scores. Therefore, physical effort may act as a form of desirable difficulty during learning. In Experiment 2 ( N = 30), the influence of physical effort on JOL s and learning disappeared when more difficult nouns were to be learned, implying that a high cognitive load may diminish bodily effects. These findings suggest that physical effort mainly influences superficial modes of thought and raise doubts concerning the explanatory power of metaphor-centered accounts of embodiment for higher-level cognition.

  11. Effort-Based Career Opportunities and Working Time

    OpenAIRE

    Bratti, M.; Staffolani, S.

    2005-01-01

    The authors evaluate the economic effects of the hypothesis of effort-based career opportunities, described as a situation in which a firm creates incentives for employees to work longer hours than bargained (or desired), by making career prospects depend on relative working hours. Firms' personnel management policies may tend to increase working time (or workers' effort) in order to maximize profits. Effort-based career opportunities raise working time, production and output per worker, and ...

  12. The Role of Cognitive Effort in Framing Effects

    OpenAIRE

    Krzysztof Przybyszewski; Dorota Rutkowska

    2013-01-01

    Framing effects are a common bias in people making risky decisions. The account for this bias is found in the loss aversion derived from Prospect Theory. Most often in the decision making literature this is the effortful processes that are claimed to reduce framing effects in risky choice tasks i.e. investing of mental effort should de-bias the decision makers. However, in goal framing studies, effortful mental processes may produce those effects. In our experiment participants were primed wi...

  13. Greater effort increases perceived value in an invertebrate.

    Science.gov (United States)

    Czaczkes, Tomer J; Brandstetter, Birgit; di Stefano, Isabella; Heinze, Jürgen

    2018-05-01

    Expending effort is generally considered to be undesirable. However, both humans and vertebrates will work for a reward they could also get for free. Moreover, cues associated with high-effort rewards are preferred to low-effort associated cues. Many explanations for these counterintuitive findings have been suggested, including cognitive dissonance (self-justification) or a greater contrast in state (e.g., energy or frustration level) before and after an effort-linked reward. Here, we test whether effort expenditure also increases perceived value in ants, using both classical cue-association methods and pheromone deposition, which correlates with perceived value. In 2 separate experimental setups, we show that pheromone deposition is higher toward the reward that requires more effort: 47% more pheromone deposition was performed for rewards reached via a vertical runway (high effort) compared with ones reached via a horizontal runway (low effort), and deposition rates were 28% higher on rough (high effort) versus smooth (low effort) runways. Using traditional cue-association methods, 63% of ants trained on different surface roughness, and 70% of ants trained on different runway elevations, preferred the high-effort related cues on a Y maze. Finally, pheromone deposition to feeders requiring memorization of one path bifurcation was up to 29% higher than to an identical feeder requiring no learning. Our results suggest that effort affects value perception in ants. This effect may stem from a cognitive process, which monitors the change in a generalized hedonic state before and after reward. (PsycINFO Database Record (c) 2018 APA, all rights reserved).

  14. A website evaluation model by integration of previous evaluation models using a quantitative approach

    Directory of Open Access Journals (Sweden)

    Ali Moeini

    2015-01-01

    Full Text Available Regarding the ecommerce growth, websites play an essential role in business success. Therefore, many authors have offered website evaluation models since 1995. Although, the multiplicity and diversity of evaluation models make it difficult to integrate them into a single comprehensive model. In this paper a quantitative method has been used to integrate previous models into a comprehensive model that is compatible with them. In this approach the researcher judgment has no role in integration of models and the new model takes its validity from 93 previous models and systematic quantitative approach.

  15. Prevalent musculoskeletal pain as a correlate of previous exposure to torture

    DEFF Research Database (Denmark)

    Olsen, Dorte Reff; Montgomery, Edith; Bojholm, S

    2006-01-01

    AIM: To research possible associations between previous exposure to specific torture techniques and prevalent pain in the head and face, back, and feet. METHODS: 221 refugees, 193 males and 28 females, previously exposed to torture in their home country, were subject to a clinical interview...... was general abuse of the whole body (OR 5.64, 95% CI 1.93-16.45). CONCLUSION: In spite of many factors being potentially co-responsible for prevalent pain, years after the torture took place it presents itself as strongly associated with specific loci of pain, with generalized effects, and with somatizing....

  16. Leveraging the International Polar Year Legacy: Providing Historical Perspective for IPY Education, Outreach and Communication Efforts

    Science.gov (United States)

    Tsukernik, M.; McCaffrey, M. S.

    2006-12-01

    As the International Polar Year 2007-2008 (IPY) is fast approaching, it is important to look back and learn from the previous experience. Over 125 years ago, when an Austrian explorer and naval officer Lt. Karl Weyprecht called for an international yearlong intensive effort to study the Polar Regions, he probably never imagined that his model for international collaboration would become so widely popular. Frustrated by the lack of coordinated, international collaboration in research activities, Weyprecht proposed an intensive burst of research activity over the course of at least a year. The first IPY began in 1882 with 12 nations establishing 13 stations in the Arctic and 2 in the Southern Hemisphere. The initial yearlong plan did not go beyond data collection. However, the idea lived in the minds of scientists worldwide and the second IPY followed the first one 50 years later. By 1932, technology evolved significantly, and on top of ground-based meteorological and geophysical measurements, data collection also included radiosonde and acoustic atmospheric measurements. Occurring during a global economic depression, and between world wars, the second IPY faced many challenges. However, 40 permanent stations were established, some of which are still active. Scientific exploration also reached remote frontiers from Antarctica to the Earth's ionosphere. Less than a decade after the WWII, the idea of the next IPY started to circulate in scientific circles. The world was focused on space exploration and the word "polar" seemed too narrow for the gigantic projects planned for the 1957. That is why the initial idea of the third IPY evolved into the International Geophysical Year (IGY), although polar regions were still a major focus. The success of the IGY is almost overwhelming the first Earth orbiting satellites, a traverse of Antarctica, a discovery of the Radiation Belt, a series of science education films about IGY activities and research themes are just a few

  17. Stretch-sensitive paresis and effort perception in hemiparesis.

    Science.gov (United States)

    Vinti, Maria; Bayle, Nicolas; Hutin, Emilie; Burke, David; Gracies, Jean-Michel

    2015-08-01

    In spastic paresis, stretch applied to the antagonist increases its inappropriate recruitment during agonist command (spastic co-contraction). It is unknown whether antagonist stretch: (1) also affects agonist recruitment; (2) alters effort perception. We quantified voluntary activation of ankle dorsiflexors, effort perception, and plantar flexor co-contraction during graded dorsiflexion efforts at two gastrocnemius lengths. Eighteen healthy (age 41 ± 13) and 18 hemiparetic (age 54 ± 12) subjects performed light, medium and maximal isometric dorsiflexion efforts with the knee flexed or extended. We determined dorsiflexor torque, Root Mean Square EMG and Agonist Recruitment/Co-contraction Indices (ARI/CCI) from the 500 ms peak voluntary agonist recruitment in a 5-s maximal isometric effort in tibialis anterior, soleus and medial gastrocnemius. Subjects retrospectively reported effort perception on a 10-point visual analog scale. During gastrocnemius stretch in hemiparetic subjects, we observed: (1) a 25 ± 7 % reduction of tibialis anterior voluntary activation (maximum reduction 98 %; knee extended vs knee flexed; p = 0.007, ANOVA); (2) an increase in dorsiflexion effort perception (p = 0.03, ANCOVA). Such changes did not occur in healthy subjects. Effort perception depended on tibialis anterior recruitment only (βARI(TA) = 0.61, p hemiparesis, voluntary ability to recruit agonist motoneurones is impaired--sometimes abolished--by antagonist stretch, a phenomenon defined here as stretch-sensitive paresis. In addition, spastic co-contraction increases effort perception, an additional incentive to evaluate and treat this phenomenon.

  18. Sharing Information among Various Organizations in Relief Efforts

    National Research Council Canada - National Science Library

    Costur, Gurkan

    2005-01-01

    .... An analysis is presented of the December 2004 Indian Ocean tsunami relief effort; specifically, how different organizations such as the military, United Nations, and non-governmental organizations...

  19. Stochastic evolutionary dynamics in minimum-effort coordination games

    Science.gov (United States)

    Li, Kun; Cong, Rui; Wang, Long

    2016-08-01

    The minimum-effort coordination game draws recently more attention for the fact that human behavior in this social dilemma is often inconsistent with the predictions of classical game theory. Here, we combine evolutionary game theory and coalescence theory to investigate this game in finite populations. Both analytic results and individual-based simulations show that effort costs play a key role in the evolution of contribution levels, which is in good agreement with those observed experimentally. Besides well-mixed populations, set structured populations have also been taken into consideration. Therein we find that large number of sets and moderate migration rate greatly promote effort levels, especially for high effort costs.

  20. The Relationship Between the Effort-Reward Imbalance and Psychosocial Health in Nurses

    Directory of Open Access Journals (Sweden)

    Fariborz Roshangar

    2017-09-01

    Full Text Available The health of nurses as providers of health affects the quality of care provided by health care organizations to patients. The effort-reward imbalance is accompanied by repressive responses that can lead to physical and psychological diseases as well as stressful experiences in nurses’ activity. Regarding the existence of some discrimination in the system of health, the present study was conducted to determine the relationship between the effort-reward imbalance and psychosocial health in nurses. In this descriptive cross-sectional study, 270 nurses working in five medical-educational centers in Tabriz participated through random-quota sampling. The research tool included a demographic questionnaire, Siegrist effort- reward imbalance questionnaire and Copenhagen Psychosocial questionnaire. Data were analyzed by SPSS V18 and descriptive and inferential statistics. In the present study, 54.8% of the patients were suffering from effort- reward imbalance model (occupational stress. The relatively high prevalence of this can be attributed to the conditions of the hospital's working environment. The results of this study showed a significant relationship between psychosocial health and balance of reward and effort in nurses and also the findings of the research showed a positive and significant relationship between mental and social health and the score of effort-reward imbalance model (0.95 = R, and P <0.05. There was a significant relationship between effort and work commitment and job burnout. Considering the stressful nature of the profession among many reasons, the mental health of nurses is at a higher risk than that of other groups in the society. Because some factors related to the imbalance in the effort and reward (stress is inevitable, it is necessary in the profession of nursing for managers to review their employees' position and characteristics to find out their staff’s attitudes and behaviors and direct them in the right path.

  1. Research and technology, 1993

    Science.gov (United States)

    1994-01-01

    Selected research and technology activities at Ames Research Center, including the Moffett Field site and the Dryden Flight Research Facility, are summarized. These activities exemplify the center's varied and productive research efforts for 1993. This year's report presents some of the challenging work recently accomplished in the areas of aerospace systems, flight operations and research, aerophysics, and space research.

  2. Safety enhancement efforts after Fukushima accident in Korea

    Energy Technology Data Exchange (ETDEWEB)

    Lee, U.C., E-mail: uclee@nssc.go.kr [Nuclear Safety & Security Commission, Seoul (Korea, Republic of)

    2014-07-01

    , 2011. The regulatory function was hence completely separated from the promotion and utilization of nuclear power. Since its establishment, NSSC has continuously been putting in effort to strengthen regulatory practice and system up to international standards. In particular, it has been proceeding with statute revision in relation to obligating severe accident evaluation, enhancing periodic safety evaluation etc and reviewing safety evaluation measure during extreme disaster situation. Additionally, it is revising the bill to expand regulatory scope to include the operator, design, manufacture, supply, qualification test companies throughout the life cycle of NPPs. Furthermore, 'Coordination Committee on Nuclear Safety Policy' (tentative) is to be established for the purpose of supporting and promoting consistency in nuclear safety related policies such as nuclear safety research, accident-failure information, safety of food and medical equipment, radiation in agriculture-livestock-marine product and ground water which are under jurisdiction of different Ministries. One of the most important lessons-learned from the Fukushima accident is communication with the public. NSSC has been emphasizing active and transparent disclosure of information through websites, blogs, SNS etc in order to relieve anxiety and restore public confidence. Other efforts include securing constant communication channel by organizing regional conference to disclose information, discuss issues, and receive feedbacks. Apart from the lessons learned from the Fukushima accident, the Korean Government is expanding its efforts to ensure nuclear safety in other areas such as CFSI issues. It is pushing forward to broaden regulatory scope to include the operator, design, manufacture, supply as well as investigation agencies. As for the management of performance verification agencies, it is to be under direct jurisdiction of the regulatory body. (author)

  3. Surveillance for previously unmonitored organic contaminants in the San Francisco Estuary.

    Science.gov (United States)

    Oros, Daniel R; Jarman, Walter M; Lowe, Theresa; David, Nicole; Lowe, Sarah; Davis, Jay A

    2003-09-01

    The San Francisco Estuary Regional Monitoring Program initiated surveillance monitoring to identify previously unmonitored synthetic organic contaminants in the San Francisco Estuary. Organic extracts of water samples were analyzed using gas chromatography-mass spectrometry in full scan mode. The major contaminant classes identified in the samples were fire retardants, pesticides, personal care product ingredients, and plasticizers. Evidence from the literature suggests that some of these contaminants can persist in the environment, induce toxicity, and accumulate in marine biota and in higher food chain consumers. The major sources of these contaminants into the marine environment are the discharge of municipal and industrial wastewater effluents, urban stormwater, and agricultural runoff. As a proactive effort, it is suggested that surveillance studies be used routinely in monitoring programs to identify and prevent potential problem contaminants from harming the marine environment.

  4. Mediastinal involvement in lymphangiomatosis: a previously unreported MRI sign

    Energy Technology Data Exchange (ETDEWEB)

    Shah, Vikas; Shah, Sachit; Barnacle, Alex; McHugh, Kieran [Great Ormond Street Hospital for Children, Department of Radiology, London (United Kingdom); Sebire, Neil J. [Great Ormond Street Hospital for Children, Department of Histopathology, London (United Kingdom); Brock, Penelope [Great Ormond Street Hospital for Children, Department of Oncology, London (United Kingdom); Harper, John I. [Great Ormond Street Hospital for Children, Department of Dermatology, London (United Kingdom)

    2011-08-15

    Multifocal lymphangiomatosis is a rare systemic disorder affecting children. Due to its rarity and wide spectrum of clinical, histological and imaging features, establishing the diagnosis of multifocal lymphangiomatosis can be challenging. The purpose of this study was to describe a new imaging sign in this disorder: paraspinal soft tissue and signal abnormality at MRI. We retrospectively reviewed the imaging, clinical and histopathological findings in a cohort of eight children with thoracic involvement from this condition. Evidence of paraspinal chest disease was identified at MRI and CT in all eight of these children. The changes comprise heterogeneous intermediate-to-high signal parallel to the thoracic vertebrae on T2-weighted sequences at MRI, with abnormal paraspinal soft tissue at CT and plain radiography. Multifocal lymphangiomatosis is a rare disorder with a broad range of clinicopathological and imaging features. MRI allows complete evaluation of disease extent without the use of ionising radiation and has allowed us to describe a previously unreported imaging sign in this disorder, namely, heterogeneous hyperintense signal in abnormal paraspinal tissue on T2-weighted images. (orig.)

  5. Cerebral Metastasis from a Previously Undiagnosed Appendiceal Adenocarcinoma

    Directory of Open Access Journals (Sweden)

    Antonio Biroli

    2012-01-01

    Full Text Available Brain metastases arise in 10%–40% of all cancer patients. Up to one third of the patients do not have previous cancer history. We report a case of a 67-years-old male patient who presented with confusion, tremor, and apraxia. A brain MRI revealed an isolated right temporal lobe lesion. A thorax-abdomen-pelvis CT scan showed no primary lesion. The patient underwent a craniotomy with gross-total resection. Histopathology revealed an intestinal-type adenocarcinoma. A colonoscopy found no primary lesion, but a PET-CT scan showed elevated FDG uptake in the appendiceal nodule. A right hemicolectomy was performed, and the specimen showed a moderately differentiated mucinous appendiceal adenocarcinoma. Whole brain radiotherapy was administrated. A subsequent thorax-abdomen CT scan revealed multiple lung and hepatic metastasis. Seven months later, the patient died of disease progression. In cases of undiagnosed primary lesions, patients present in better general condition, but overall survival does not change. Eventual identification of the primary tumor does not affect survival. PET/CT might be a helpful tool in detecting lesions of the appendiceal region. To the best of our knowledge, such a case was never reported in the literature, and an appendiceal malignancy should be suspected in patients with brain metastasis from an undiagnosed primary tumor.

  6. Coronary collateral vessels in patients with previous myocardial infarction

    International Nuclear Information System (INIS)

    Nakatsuka, M.; Matsuda, Y.; Ozaki, M.

    1987-01-01

    To assess the degree of collateral vessels after myocardial infarction, coronary angiograms, left ventriculograms, and exercise thallium-201 myocardial scintigrams of 36 patients with previous myocardial infarction were reviewed. All 36 patients had total occlusion of infarct-related coronary artery and no more than 70% stenosis in other coronary arteries. In 19 of 36 patients with transient reduction of thallium-201 uptake in the infarcted area during exercise (Group A), good collaterals were observed in 10 patients, intermediate collaterals in 7 patients, and poor collaterals in 2 patients. In 17 of 36 patients without transient reduction of thallium-201 uptake in the infarcted area during exercise (Group B), good collaterals were seen in 2 patients, intermediate collaterals in 7 patients, and poor collaterals in 8 patients (p less than 0.025). Left ventricular contractions in the infarcted area were normal or hypokinetic in 10 patients and akinetic or dyskinetic in 9 patients in Group A. In Group B, 1 patient had hypokinetic contraction and 16 patients had akinetic or dyskinetic contraction (p less than 0.005). Thus, patients with transient reduction of thallium-201 uptake in the infarcted area during exercise had well developed collaterals and preserved left ventricular contraction, compared to those in patients without transient reduction of thallium-201 uptake in the infarcted area during exercise. These results suggest that the presence of viable myocardium in the infarcted area might be related to the degree of collateral vessels

  7. High-Grade Leiomyosarcoma Arising in a Previously Replanted Limb

    Directory of Open Access Journals (Sweden)

    Tiffany J. Pan

    2015-01-01

    Full Text Available Sarcoma development has been associated with genetics, irradiation, viral infections, and immunodeficiency. Reports of sarcomas arising in the setting of prior trauma, as in burn scars or fracture sites, are rare. We report a case of a leiomyosarcoma arising in an arm that had previously been replanted at the level of the elbow joint following traumatic amputation when the patient was eight years old. He presented twenty-four years later with a 10.8 cm mass in the replanted arm located on the volar forearm. The tumor was completely resected and pathology examination showed a high-grade, subfascial spindle cell sarcoma diagnosed as a grade 3 leiomyosarcoma with stage pT2bNxMx. The patient underwent treatment with brachytherapy, reconstruction with a free flap, and subsequently chemotherapy. To the best of our knowledge, this is the first case report of leiomyosarcoma developing in a replanted extremity. Development of leiomyosarcoma in this case could be related to revascularization, scar formation, or chronic injury after replantation. The patient remains healthy without signs of recurrence at three-year follow-up.

  8. Global functional atlas of Escherichia coli encompassing previously uncharacterized proteins.

    Directory of Open Access Journals (Sweden)

    Pingzhao Hu

    2009-04-01

    Full Text Available One-third of the 4,225 protein-coding genes of Escherichia coli K-12 remain functionally unannotated (orphans. Many map to distant clades such as Archaea, suggesting involvement in basic prokaryotic traits, whereas others appear restricted to E. coli, including pathogenic strains. To elucidate the orphans' biological roles, we performed an extensive proteomic survey using affinity-tagged E. coli strains and generated comprehensive genomic context inferences to derive a high-confidence compendium for virtually the entire proteome consisting of 5,993 putative physical interactions and 74,776 putative functional associations, most of which are novel. Clustering of the respective probabilistic networks revealed putative orphan membership in discrete multiprotein complexes and functional modules together with annotated gene products, whereas a machine-learning strategy based on network integration implicated the orphans in specific biological processes. We provide additional experimental evidence supporting orphan participation in protein synthesis, amino acid metabolism, biofilm formation, motility, and assembly of the bacterial cell envelope. This resource provides a "systems-wide" functional blueprint of a model microbe, with insights into the biological and evolutionary significance of previously uncharacterized proteins.

  9. Global functional atlas of Escherichia coli encompassing previously uncharacterized proteins.

    Science.gov (United States)

    Hu, Pingzhao; Janga, Sarath Chandra; Babu, Mohan; Díaz-Mejía, J Javier; Butland, Gareth; Yang, Wenhong; Pogoutse, Oxana; Guo, Xinghua; Phanse, Sadhna; Wong, Peter; Chandran, Shamanta; Christopoulos, Constantine; Nazarians-Armavil, Anaies; Nasseri, Negin Karimi; Musso, Gabriel; Ali, Mehrab; Nazemof, Nazila; Eroukova, Veronika; Golshani, Ashkan; Paccanaro, Alberto; Greenblatt, Jack F; Moreno-Hagelsieb, Gabriel; Emili, Andrew

    2009-04-28

    One-third of the 4,225 protein-coding genes of Escherichia coli K-12 remain functionally unannotated (orphans). Many map to distant clades such as Archaea, suggesting involvement in basic prokaryotic traits, whereas others appear restricted to E. coli, including pathogenic strains. To elucidate the orphans' biological roles, we performed an extensive proteomic survey using affinity-tagged E. coli strains and generated comprehensive genomic context inferences to derive a high-confidence compendium for virtually the entire proteome consisting of 5,993 putative physical interactions and 74,776 putative functional associations, most of which are novel. Clustering of the respective probabilistic networks revealed putative orphan membership in discrete multiprotein complexes and functional modules together with annotated gene products, whereas a machine-learning strategy based on network integration implicated the orphans in specific biological processes. We provide additional experimental evidence supporting orphan participation in protein synthesis, amino acid metabolism, biofilm formation, motility, and assembly of the bacterial cell envelope. This resource provides a "systems-wide" functional blueprint of a model microbe, with insights into the biological and evolutionary significance of previously uncharacterized proteins.

  10. Gastrointestinal tolerability with ibandronate after previous weekly bisphosphonate treatment.

    Science.gov (United States)

    Derman, Richard; Kohles, Joseph D; Babbitt, Ann

    2009-01-01

    Data from two open-label trials (PRIOR and CURRENT) of women with postmenopausal osteoporosis or osteopenia were evaluated to assess whether monthly oral and quarterly intravenous (IV) ibandronate dosing improved self-reported gastrointestinal (GI) tolerability for patients who had previously experienced GI irritation with bisphosphonate (BP) use. In PRIOR, women who had discontinued daily or weekly BP treatment due to GI intolerance received monthly oral or quarterly IV ibandronate for 12 months. The CURRENT subanalysis included women receiving weekly BP treatment who switched to monthly oral ibandronate for six months. GI symptom severity and frequency were assessed using the Osteoporosis Patient Satisfaction Questionnaire. In PRIOR, mean GI tolerability scores increased significantly at month 1 from screening for both treatment groups (oral: 79.3 versus 54.1; IV: 84.4 versus 51.0; p 90% at Month 10). In the CURRENT subanalysis >60% of patients reported improvements in heartburn or acid reflux and >70% indicated improvement in other stomach upset at month 6. Postmenopausal women with GI irritability with daily or weekly BPs experienced improvement in symptoms with extended dosing monthly or quarterly ibandronate compared with baseline.

  11. Pertussis-associated persistent cough in previously vaccinated children.

    Science.gov (United States)

    Principi, Nicola; Litt, David; Terranova, Leonardo; Picca, Marina; Malvaso, Concetta; Vitale, Cettina; Fry, Norman K; Esposito, Susanna

    2017-11-01

    To evaluate the role of Bordetella pertussis infection, 96 otherwise healthy 7- to 17-year-old subjects who were suffering from a cough lasting from 2 to 8 weeks were prospectively recruited. At enrolment, a nasopharyngeal swab and an oral fluid sample were obtained to search for pertussis infection by the detection of B. pertussis DNA and/or an elevated titre of anti-pertussis toxin IgG. Evidence of pertussis infection was found in 18 (18.7 %; 95 % confidence interval, 11.5-28.0) cases. In 15 cases, the disease occurred despite booster administration. In two cases, pertussis was diagnosed less than 2 years after the booster injection, whereas in the other cases it was diagnosed between 2 and 9 years after the booster dose. This study used non-invasive testing to show that pertussis is one of the most important causes of long-lasting cough in school-age subjects. Moreover, the protection offered by acellular pertussis vaccines currently wanes more rapidly than previously thought.

  12. Multispecies Coevolution Particle Swarm Optimization Based on Previous Search History

    Directory of Open Access Journals (Sweden)

    Danping Wang

    2017-01-01

    Full Text Available A hybrid coevolution particle swarm optimization algorithm with dynamic multispecies strategy based on K-means clustering and nonrevisit strategy based on Binary Space Partitioning fitness tree (called MCPSO-PSH is proposed. Previous search history memorized into the Binary Space Partitioning fitness tree can effectively restrain the individuals’ revisit phenomenon. The whole population is partitioned into several subspecies and cooperative coevolution is realized by an information communication mechanism between subspecies, which can enhance the global search ability of particles and avoid premature convergence to local optimum. To demonstrate the power of the method, comparisons between the proposed algorithm and state-of-the-art algorithms are grouped into two categories: 10 basic benchmark functions (10-dimensional and 30-dimensional, 10 CEC2005 benchmark functions (30-dimensional, and a real-world problem (multilevel image segmentation problems. Experimental results show that MCPSO-PSH displays a competitive performance compared to the other swarm-based or evolutionary algorithms in terms of solution accuracy and statistical tests.

  13. Autonomic nervous system responses during perception of masked speech may reflect constructs other than subjective listening effort

    Directory of Open Access Journals (Sweden)

    Alexander L. Francis

    2016-03-01

    Full Text Available Typically, understanding speech seems effortless and automatic. However, a variety of factors may, independently or interactively, make listening more effortful. Physiological measures may help to distinguish between the application of different cognitive mechanisms whose operation is perceived as effortful. In the present study, physiological and behavioral measures associated with task demand were collected along with behavioral measures of performance while participants listened to and repeated sentences. The goal was to measure psychophysiological reactivity associated with three degraded listening conditions, each of which differed in terms of the source of the difficulty (distortion, energetic masking, and informational masking, and therefore were expected to engage different cognitive mechanisms. These conditions were chosen to be matched for overall performance (keywords correct, and were compared to listening to unmasked speech produced by a natural voice. The three degraded conditions were: (1 Unmasked speech produced by a computer speech synthesizer, (2 Speech produced by a natural voice and masked by speech-shaped noise and (3 Speech produced by a natural voice and masked by two-talker babble. Masked conditions were both presented at a -8 dB signal to noise ratio (SNR, a level shown in previous research to result in comparable levels of performance for these stimuli and maskers. Performance was measured in terms of proportion of key words identified correctly, and task demand or effort was quantified subjectively by self-report. Measures of psychophysiological reactivity included electrodermal (skin conductance response frequency and amplitude, blood pulse amplitude and pulse rate. Results suggest that the two masked conditions evoked stronger psychophysiological reactivity than did the two unmasked conditions even when behavioral measures of listening performance and listeners’ subjective perception of task demand were comparable

  14. Transvestism: previous findings and new areas for inquiry.

    Science.gov (United States)

    Wise, T N; Meyer, J K

    1980-01-01

    The transvestite is a heterosexual fetishistic cross-dresser. The phenomenology of the disorder reveals individuals to be heterosexual males who have usually married and fathered children. The course of the disorder is unknown. Many transvestites note genital arousal from cross-dressing abates, yet continue episodically to wear women's clothes. A small segment of these individuals become gender dysphoric and seek sexual reassignment. Etiologic explanations include pregenital psychopathology in the genesis of the condition. The treatment for transvestism remains disappointing although behavior modification may offer individuals who wish to change their transvestitic behavior some hope. This review suggests new areas for inquiry and possible research strategies.

  15. European Technological Effort in Preparation of ITER Construction

    International Nuclear Information System (INIS)

    Andreani, Roberto

    2005-01-01

    Europe has started since the '80s with the preparatory work done on NET, the Next European Torus, the successor of JET, to prepare for the construction of the next generation experiment on the road to the fusion reactor. In 2000 the European Fusion Development Agreement (EFDA) has been signed by sixteen countries, including Switzerland, not a member of the Union. Now the signatory countries have increased to twenty-five. A vigorous programme of design and R and D in support of ITER construction has been conducted by EFDA through the coordinated effort of the national institutes and laboratories supported financially, in the framework of the VI European Framework Research Programme (2002-2006), by contracts of association with EURATOM. In the last three years, with the expenditure of 160 M[Euro], the accent has been particularly put on the preparation of the industrial manufacturing activities of components and systems for ITER. Prototypes and manufacturing methods have been developed in all the main critical areas of machine construction with the objective of providing sound and effective solutions: vacuum vessel, toroidal field coils, poloidal field coils, remote handling equipment, plasma facing components and divertor components, electrical power supplies, generators and power supplies for the Heating and Current Drive Systems and other minor subsystems.Europe feels to be ready to host the ITER site and to provide adequate support and guidance for the success of construction to our partners in the ITER collaboration, wherever needed

  16. Social entrepreneurship in religious congregations' efforts to address health needs.

    Science.gov (United States)

    Werber, Laura; Mendel, Peter J; Derose, Kathryn Pitkin

    2014-01-01

    Examine how religious congregations engage in social entrepreneurship as they strive to meet health-related needs in their communities. Multiple case studies. Los Angeles County, California. Purposive sample of 14 congregations representing diverse races/ethnicities (African-American, Latino, and white) and faith traditions (Jewish and various Christian). Congregations were recruited based on screening data and consultation of a community advisory board. In each congregation, researchers conducted interviews with clergy and lay leaders (n = 57); administered a congregational questionnaire; observed health activities, worship services, and neighborhood context; and reviewed archival information. Interviews were analyzed by using a qualitative, code-based approach. Congregations' health-related activities tended to be episodic, small in scale, and local in scope. Trust and social capital played important roles in congregations' health initiatives, providing a safe, confidential environment and leveraging resources from-and for-faith-based and secular organizations in their community networks. Congregations also served as "incubators" for members to engage in social entrepreneurship. Although the small scale of congregations' health initiatives suggest they may not have the capacity to provide the main infrastructure for service provision, congregations can complement the efforts of health and social providers with their unique strengths. Specifically, congregations are distinctive in their ability to identify unmet local needs, and congregations' position in their communities permit them to network in productive ways.

  17. Social Entrepreneurship in Religious Congregations’ Efforts to Address Health Needs

    Science.gov (United States)

    Werber, Laura; Mendel, Peter J.; Derose, Kathryn Pitkin

    2013-01-01

    Purpose Examine how religious congregations engage in social entrepreneurship as they strive to meet health-related needs in their communities. Design Multiple case studies. Setting Los Angeles County, California. Participants Purposive sample of 14 congregations representing diverse races-ethnicities (African American, Latino, and white) and faith traditions (Jewish and various Christian). Method Congregations were recruited based on screening data and consultation of a community advisory board. In each congregation, researchers conducted interviews with clergy and lay leaders (n=57); administered a congregational questionnaire; observed health activities, worship services, and neighborhood context; and reviewed archival information. Interviews were analyzed using a qualitative, code-based approach. Results Congregations’ health-related activities tended to be episodic, small in scale, and local in scope. Trust and social capital played important roles in congregations’ health initiatives, providing a safe, confidential environment and leveraging resources from – and for – faith-based and secular organizations in their community networks. Congregations also served as “incubators” for members to engage in social entrepreneurship. Conclusion Although the small scale of congregations’ health initiatives suggest they may not have the capacity to provide the main infrastructure for service provision, congregations can complement the efforts of health and social providers with their unique strengths. Specifically, congregations are distinctive in their ability to identify unmet local needs, and congregations’ position in their communities permit them to network in productive ways. PMID:23875986

  18. Central diabetes insipidus: a previously unreported side effect of temozolomide.

    Science.gov (United States)

    Faje, Alexander T; Nachtigall, Lisa; Wexler, Deborah; Miller, Karen K; Klibanski, Anne; Makimura, Hideo

    2013-10-01

    Temozolomide (TMZ) is an alkylating agent primarily used to treat tumors of the central nervous system. We describe 2 patients with apparent TMZ-induced central diabetes insipidus. Using our institution's Research Patient Database Registry, we identified 3 additional potential cases of TMZ-induced diabetes insipidus among a group of 1545 patients treated with TMZ. A 53-year-old male with an oligoastrocytoma and a 38-year-old male with an oligodendroglioma each developed symptoms of polydipsia and polyuria approximately 2 months after the initiation of TMZ. Laboratory analyses demonstrated hypernatremia and urinary concentrating defects, consistent with the presence of diabetes insipidus, and the patients were successfully treated with desmopressin acetate. Desmopressin acetate was withdrawn after the discontinuation of TMZ, and diabetes insipidus did not recur. Magnetic resonance imaging of the pituitary and hypothalamus was unremarkable apart from the absence of a posterior pituitary bright spot in both of the cases. Anterior pituitary function tests were normal in both cases. Using the Research Patient Database Registry database, we identified the 2 index cases and 3 additional potential cases of diabetes insipidus for an estimated prevalence of 0.3% (5 cases of diabetes insipidus per 1545 patients prescribed TMZ). Central diabetes insipidus is a rare but reversible side effect of treatment with TMZ.

  19. "I put in effort, therefore I am passionate": Investigating the path from effort to passion in entrepreneurship

    OpenAIRE

    Gielnik, Michael Marcus; Spitzmuller, Matthias; Schmitt, Antje; Klemann, Katharina; Frese, Michael

    2015-01-01

    Most theoretical frameworks in entrepreneurship emphasize that entrepreneurial passion drives entrepreneurial effort. We hypothesize that the reverse effect is also true, and investigate changes in passion as an outcome of effort. Based on theories of self-regulation and self-perception, we hypothesize that making new venture progress and free choice are two factors that help to explain why and under which conditions entrepreneurial effort affects entrepreneurial passion. We undertook two stu...

  20. Impulsivity moderates the relationship between previous quit failure and cue-induced craving.

    Science.gov (United States)

    Erblich, Joel; Michalowski, Alexandra

    2015-12-01

    Poor inhibitory control has been shown to be an important predictor of relapse to a number of drugs, including nicotine. Indeed, smokers who exhibit higher levels of impulsivity are thought to have impaired regulation of urges to smoke, and previous research has suggested that impulsivity may moderate cue-induced cigarette cravings. To that end, we conducted a study to evaluate the interplay between failed smoking cessation, cue-induced craving, and impulsivity. Current smokers (n=151) rated their cigarette cravings before and after laboratory to exposure to smoking cues, and completed questionnaires assessing impulsivity and previous failed quit attempts. Findings indicated that shorter duration of previous failed quit attempts was related to higher cue-induced cigarette craving, especially among smokers with higher levels of impulsivity. Results underscore the importance of considering trait impulsivity as a factor in better understanding the management of cue-induced cravings. Copyright © 2015 Elsevier Ltd. All rights reserved.