WorldWideScience

Sample records for prevention proposed rule

  1. Allowance System: Proposed acid-rain rule

    International Nuclear Information System (INIS)

    1991-12-01

    The U.S. Environmental Protection Agency (EPA) has proposed four rules containing the core acid rain requirements: the Permits Rule (40 CFR Part 72), the Allowance System Rule (40 CFR Part 73), the Continuous Emission Monitoring Rule (40 CFR Part 75), and the Excess Emissions Rule (40 CFR Part 77). EPA will also propose additional rules at a future date. These rules will include requirements for facilities that elect to opt into the Acid Rain Program (40 CFR Part 74) and for the nitrogen oxide (NOx) control program (40 CFR Part 76). The fact sheet summarizes the key components of EPA's proposed Allowance System

  2. 50 CFR 424.16 - Proposed rules.

    Science.gov (United States)

    2010-10-01

    ... 50 Wildlife and Fisheries 7 2010-10-01 2010-10-01 false Proposed rules. 424.16 Section 424.16... OF COMMERCE); ENDANGERED SPECIES COMMITTEE REGULATIONS SUBCHAPTER A LISTING ENDANGERED AND THREATENED SPECIES AND DESIGNATING CRITICAL HABITAT Revision of the Lists § 424.16 Proposed rules. (a) General. Based...

  3. Proposed Rule: Strengthening Transparency in Regulatory Science

    Science.gov (United States)

    April 24, 2018 proposed rule providing that when EPA develops regulations, including regulations for which the public is likely to bear the cost of compliance, with regard to those scientific studies that are pivotal to the action being taken, EPA should e

  4. CFC rules in the context of the proposed CCCTB directive

    Directory of Open Access Journals (Sweden)

    Veronika Sobotková

    2011-01-01

    Full Text Available In the proposal for a Council Directive on a Common Consolidated Corporate Tax Base (CCCTB there have been introduced a specific anti-abuse provisions, CFC rules. These rules are aimed at tax evasions and tax avoidance. The basic principle is the protection of the tax base against erosion through practices of artificial income shifting. Generally, CFC rules prevent tax avoidance in a state of a shareholder by denying the deferred taxation of profits generated by its controlled company, which is a resident in a tax preference jurisdiction. Even thought the CCCTB directive would be aided easier and low-costs cross-border business as well as it would be restricted the harmful tax competition there are questions whether it is advisable to introduce these rules into such system of the CCCTB, whether these rules are compatible with the CCCTB and whether it is regulated properly. So, the focus of this paper rests on the interaction of the proposed CCCTB directive with existing CFC rules in the European Union. The paper deals with pros and cons, economic and legal perspectives these rules in the context of the proposed CCCTB directive.

  5. A PROPOSAL OF FUZZY MULTIDIMENSIONAL ASSOCIATION RULES

    Directory of Open Access Journals (Sweden)

    Rolly Intan

    2006-01-01

    Full Text Available Association rules that involve two or more dimensions or predicates can be referred as multidimensional association rules. Rather than searching for frequent itemsets (as is done in mining single-dimensional association rules, in multidimensional association rules, we search for frequent predicate sets. In general, there are two types of multidimensional association rules, namely interdimension association rules and hybrid-dimension association rules. Interdimension association rules are multidimensional association rules with no repeated predicates. This paper introduces a method for generating interdimension association rules. A more meaningful association rules can be provided by generalizing crisp value of attributes to be fuzzy value. To generate the multidimensional association rules implying fuzzy value, this paper introduces an alternative method for mining the rules by searching for the predicate sets.

  6. Continuous-emission monitoring: Proposed acid-rain rule

    International Nuclear Information System (INIS)

    1991-12-01

    The U.S. Environmental Protection Agency (EPA) has proposed four rules containing the core acid rain requirements: the Permits Rule (40 CFR Part 72), the Allowances Rule (40 CFR Part 73), the Continuous Emission Monitoring Rule (40 CFR Part 75), and the Excess Emissions Rule (40 CRF Part 77). EPA will also propose additional rules at a future date. These rules will include requirements for facilities that elect to opt into the Acid Rain Program (40 CFR Part 74) and for the nitrogen oxide (NOx) control program (40 CFR Part 76). This fact sheet summarizes the key components of the proposed Continuous Emission Monitoring Rule (40 CFR Part 75)

  7. Economic analysis of the proposed rule to prevent arrival of new genetic strains of the rust fungus Puccinia psidii in Hawai'i.

    Science.gov (United States)

    Burnett, Kimberly; D'Evelyn, Sean; Loope, Lloyd; Wada, Christopher A.

    2012-01-01

    Since its first documented introduction to Hawai‘i in 2005, the rust fungus P. psidii has already severely damaged Syzygium jambos (Indian rose apple) trees and the federally endangered Eugenia koolauensis (nioi). Fortunately, the particular strain has yet to cause serious damage to ‘ōhi‘a, which comprises roughly 80% of the state’s native forests and covers 400,000 ha. Although the rust has affected less than 5% of Hawaii’s ‘ōhi‘a trees thus far, the introduction of more virulent strains and the genetic evolution of the current strain are still possible. Since the primary pathway of introduction is Myrtaceae plant material imported from outside the state, potential damage to ‘ohi‘a can be minimized by regulating those high-risk imports. We discuss the economic impact on the state’s florist, nursery, landscaping, and forest plantation industries of a proposed rule that would ban the import of non-seed Myrtaceae plant material and require a one-year quarantine of seeds. Our analysis suggests that the benefits to the forest plantation industry of a complete ban on non-seed material would likely outweigh the costs to other affected sectors, even without considering the reduction in risk to ‘ōhi‘a. Incorporating the value of ‘ōhi‘a protection would further increase the benefit-cost ratio in favor of an import ban.

  8. 75 FR 55728 - Withdrawal of Proposed Rules; Discontinuing Rulemaking Efforts Listed in the Unified Agenda of...

    Science.gov (United States)

    2010-09-14

    ..., Chemical Control Division (7405M), Office of Pollution Prevention and Toxics, Environmental Protection... stakeholders working with us to identify the most practical and effective solutions to problems and we stress... Proposed Test Rule for Hazardous Air Pollutants (RIN 2070-AC76) 1. What was proposed? In the Federal...

  9. Proposal to modify Rule 6, Rule 10a, and Rule 12c of the International Code of Nomenclature of Prokaryotes.

    Science.gov (United States)

    Oren, Aharon; Garrity, George M; Schink, Bernhard

    2014-04-01

    According to the current versions of Rule 10a and Rule 12c of the International Code of Nomenclature of Prokaryotes, names of a genus or subgenus and specific epithets may be taken from any source and may even be composed in an arbitrary manner. Based on these rules, names may be composed of any word or any combination of elements derived from any language with a Latin ending. We propose modifying these rules by adding the text, currently part of Recommendation 6, according to which words from languages other than Latin or Greek should be avoided as long as equivalents exist in Latin or Greek or can be constructed by combining word elements from these two languages. We also propose modification of Rule 6 by adopting some of the current paragraphs of Recommendation 6 to become part of the Rule.

  10. Family Violence Prevention and Services Programs. Final rule.

    Science.gov (United States)

    2016-11-02

    This rule will better prevent and protect survivors of family violence, domestic violence, and dating violence, by clarifying that all survivors must have access to services and programs funded under the Family Violence Prevention and Services Act. More specifically, the rule enhances accessibility and non-discrimination provisions, clarifies confidentiality rules, promotes coordination among community-based organizations, State Domestic Violence Coalitions, States, and Tribes, as well as incorporates new discretionary grant programs. Furthermore, the rule updates existing regulations to reflect statutory changes made to the Family Violence Prevention and Services Act, and updates procedures for soliciting and awarding grants. The rule also increases clarity and reduces potential confusion over statutory and regulatory standards. The rule codifies standards already used by the program in the Funding Opportunity Announcements and awards, in technical assistance, in reporting requirements, and in sub-regulatory guidance.

  11. 76 FR 72120 - Oil Pollution Prevention; Spill Prevention, Control, and Countermeasure (SPCC) Rule-Compliance...

    Science.gov (United States)

    2011-11-22

    ... Oil Pollution Prevention; Spill Prevention, Control, and Countermeasure (SPCC) Rule--Compliance Date... rule will be effective November 22, 2011. List of Subjects in 40 CFR Part 112 Oil pollution prevention... Regulations is amended as follows: PART 112--OIL POLLUTION PREVENTION 0 1. The authority citation for part 112...

  12. 75 FR 30095 - Self-Regulatory Organizations; NYSE Arca, Inc.; Order Approving Proposed Rule Amending Its...

    Science.gov (United States)

    2010-05-28

    ... market system. Specifically, the proposed rule change allows the pilot program to continue without... Commission has considered the proposed rule's impact on efficiency, competition, and capital formation. See...

  13. 77 FR 59030 - Self-Regulatory Organizations; BATS Exchange, Inc.; Order Granting Approval of Proposed Rule...

    Science.gov (United States)

    2012-09-25

    ...'' to modify the criteria for certain securities listed on BATS as Index Fund Shares. The proposed rule.... II. Description of the Proposed Rule Change Proposal To Amend Index Fund Shares Rules The Exchange proposes certain changes to Rule 14.11(c) relating to Index Fund Shares, commonly referred to as exchange...

  14. 76 FR 49479 - Franchise Rule Information Collection Activities; Proposed Collection; Comment Request

    Science.gov (United States)

    2011-08-10

    ... FEDERAL TRADE COMMISSION Franchise Rule Information Collection Activities; Proposed Collection... Concerning Franchising (``Franchise Rule''). That clearance expires on December 31, 2011. DATES: Comments... INFORMATION section below. Write ``Franchise Rule, PRA Comment, FTC File No. P094400'' on your comment, and...

  15. 78 FR 58500 - Water Quality Standards Regulatory Clarifications Proposed Rule; Public Meeting and Public Webinars

    Science.gov (United States)

    2013-09-24

    ... the proposed rule ``Water Quality Standards Regulatory Clarifications,'' which was published... the federal water quality standards (WQS) regulation at 40 CFR Part 131 which helps implement the..., the proposed rule will lead to improved water quality standard development, implementation and...

  16. 76 FR 36596 - Self-Regulatory Organizations; Chicago Stock Exchange, Inc.; Order Approving a Proposed Rule...

    Science.gov (United States)

    2011-06-22

    ... make additional rules subject to punishment under its MRP. These rules relate to: (1) Failure to notify the Exchange of a request to withdraw capital contribution (Article 3, Rule 6(b)); (2) failure to... notes that it has considered the proposed rule's impact on efficiency, competition, and capital...

  17. 78 FR 79048 - Self-Regulatory Organizations; NYSE MKT LLC; Order Approving Proposed Rule Change Amending...

    Science.gov (United States)

    2013-12-27

    ... acts and practices, to promote just and equitable principles of trade, to remove impediments to and... to the time the rule is deleted. Thus, the proposed rule change would have no impact on ongoing... Address Wash Sales in Order To Harmonize the Exchange's Rules With the Rules of New York Stock Exchange...

  18. 75 FR 81685 - Self-Regulatory Organizations; Notice of Filing and Immediate Effectiveness of Proposed Rule...

    Science.gov (United States)

    2010-12-28

    ... error. NYSE Arca Equities Rules 2.24 and 9.17 both require ETP Holders to maintain books and records pursuant to SEC Rules 17a-3 and 17a-4. Because Rule 9.17 also requires that ETP Holders maintain books and... governmental bodies, and because the Exchange only requires one such rule, the Exchange proposes to replace the...

  19. 76 FR 21652 - Oil Pollution Prevention; Spill Prevention, Control, and Countermeasure (SPCC) Rule-Amendments...

    Science.gov (United States)

    2011-04-18

    ... greases, and fish and marine mammal oils; oils of vegetable origin; other non-petroleum oils and greases; and petroleum oils. In differentiating between these classes of oils, Federal agencies are directed to... Oil Pollution Prevention; Spill Prevention, Control, and Countermeasure (SPCC) Rule--Amendments for...

  20. 75 FR 28842 - Self-Regulatory Organizations; Proposed Rule Change by Chicago Stock Exchange, Inc.; Notice of...

    Science.gov (United States)

    2010-05-24

    ... of the Proposed Rule Change CHX proposes to amend Article 20, Rule 2 to amend its rules to create... Basis for, the Proposed Rule Changes 1. Purpose The CHX is proposing to amend Article 20, Rule 2 to... received from the responsible single plan processor, the Exchange may resume trading in such stock. The...

  1. 77 FR 62547 - Self-Regulatory Organizations; NASDAQ OMX BX, Inc.; Notice of Filing of Proposed Rule Change To...

    Science.gov (United States)

    2012-10-15

    ... Organizations; NASDAQ OMX BX, Inc.; Notice of Filing of Proposed Rule Change To Modify the Listing Rules for... of the Substance of the Proposed Rule Change BX proposes to modify the listing rules for compensation... approval. Proposed BX Venture Market Listing Rule 5605(d)(3), which requires compensation committees to...

  2. Fact Sheet: Proposed Rule: State Plans to Address Emissions During Startup, Shutdown, and Malfunction (SSM)

    Science.gov (United States)

    On February 12, 2013, the U.S. Environmental Protection Agency (EPA) proposed a rule that would ensure states have plans in place that require industrial facilities across the country to follow air pollution rules during SSM operations.

  3. 76 FR 41157 - Guidance for Industry: Questions and Answers Regarding the Final Rule, Prevention of Salmonella...

    Science.gov (United States)

    2011-07-13

    ..., Prevention of Salmonella Enteritidis in Shell Eggs During Production, Storage, and Transportation... Industry: Questions and Answers Regarding the Final Rule, Prevention of Salmonella Enteritidis in Shell... Salmonella Enteritidis in Shell Eggs During Production, Storage, and Transportation'' (the final rule). The...

  4. 75 FR 4435 - Self-Regulatory Organizations; Notice of Filing and Immediate Effectiveness of Proposed Rule...

    Science.gov (United States)

    2010-01-27

    ... Commission (the ``Commission'') the proposed rule change as described in Items I, II, and III below, which... officers of the Exchange and are not affiliated with ATP Holders. The Exchange is now proposing to permit... comments were solicited or received with respect to the proposed rule change. III. Date of Effectiveness of...

  5. 78 FR 36608 - Self-Regulatory Organizations; Fixed Income Clearing Corporation; Order Approving Proposed Rule...

    Science.gov (United States)

    2013-06-18

    ... proposed rule change filing, the United Kingdom, Mexico, Ireland, Switzerland, Spain, Norway Denmark, Italy.... Customary legal agreements in the financial services industry already contain provisions allocating the risk...

  6. 77 FR 65608 - Proposed Collection; Comment Request for Revenue Ruling 2000-35

    Science.gov (United States)

    2012-10-29

    ... Internal Revenue Service Proposed Collection; Comment Request for Revenue Ruling 2000-35 AGENCY: Internal...(c)(2)(A)). Currently, the IRS is soliciting comments concerning Revenue Ruling 2000-35, Automatic...: Automatic Enrollment in Section 403(b) Plans. OMB Number: 1545-1694. Form Number: Revenue Ruling 2000-35...

  7. 18 CFR 385.912 - Proposed findings of fact, conclusions of law, and comments (Rule 912).

    Science.gov (United States)

    2010-04-01

    ... 18 Conservation of Power and Water Resources 1 2010-04-01 2010-04-01 false Proposed findings of fact, conclusions of law, and comments (Rule 912). 385.912 Section 385.912 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY PROCEDURAL RULES RULES OF...

  8. 78 FR 57538 - Proposed Waste Confidence Rule and Draft Generic Environmental Impact Statement

    Science.gov (United States)

    2013-09-19

    ...-2012-0246] RIN 3150-AJ20 Proposed Waste Confidence Rule and Draft Generic Environmental Impact... disposal (proposed Waste Confidence rule). In addition, the NRC will receive public comment on its forthcoming draft generic environmental impact statement (DGEIS), NUREG-2157, ``Waste Confidence Generic...

  9. 78 FR 54789 - Proposed Waste Confidence Rule and Draft Generic Environmental Impact Statement

    Science.gov (United States)

    2013-09-06

    ...-2012-0246] RIN 3150-AJ20 Proposed Waste Confidence Rule and Draft Generic Environmental Impact... disposal (proposed Waste Confidence rule). In addition, the NRC will receive public comment on its forthcoming draft generic environmental impact statement (DGEIS), NUREG-2157, ``Waste Confidence Generic...

  10. 75 FR 10532 - Self-Regulatory Organizations; Notice of Filing and Immediate Effectiveness of Proposed Rule...

    Science.gov (United States)

    2010-03-08

    ... Commission (the ``Commission'') the proposed rule change as described in Items I, II, and III below, which... all similarly situated ATP Holders. 2. Statutory Basis The Exchange believes that the proposed rule... to all similarly situated ATP Holders. \\4\\ 15 U.S.C. 78f(b). \\5\\ 15 U.S.C. 78f(b)(4). B. Self...

  11. 17 CFR 41.49 - Filing proposed margin rule changes with the Commission.

    Science.gov (United States)

    2010-04-01

    ... 17 Commodity and Securities Exchanges 1 2010-04-01 2010-04-01 false Filing proposed margin rule... TRADING COMMISSION SECURITY FUTURES PRODUCTS Customer Accounts and Margin Requirements § 41.49 Filing proposed margin rule changes with the Commission. (a) Notification requirement for notice-designated...

  12. 77 FR 50372 - Guidance for Industry: Questions and Answers Regarding the Final Rule, Prevention of Salmonella...

    Science.gov (United States)

    2012-08-21

    ..., Prevention of Salmonella Enteritidis in Shell Eggs During Production, Storage, and Transportation... Industry: Questions and Answers Regarding the Final Rule, Prevention of Salmonella Enteritidis in Shell... 33030), we issued a final rule requiring shell egg producers to implement measures to prevent Salmonella...

  13. Preventive Nephrology - Proposed Options in Childhood Nephropathy

    African Journals Online (AJOL)

    Three children with renal disorders managed at the University of Ilorin Teaching Hospital are reported as case studies to underscore the need for preventive nephrology . The first case illustrates the inevitability of rapidly progressive renal failure when remedial management desired in the early stages of the nephropathy is ...

  14. 77 FR 43407 - Self-Regulatory Organizations; The Options Clearing Corporation; Order Approving Proposed Rule...

    Science.gov (United States)

    2012-07-24

    ... Organizations; The Options Clearing Corporation; Order Approving Proposed Rule Change Relating to Amendments to Certain Rules Applicable to Stock Futures July 18, 2012. I. Introduction On May 24, 2012, The Options... stock options.) However, in the case of stock futures, OneChicago, the only futures exchange clearing...

  15. 78 FR 64412 - Proposed Waste Confidence Rule and Draft Generic Environmental Impact Statement

    Science.gov (United States)

    2013-10-29

    ... Confidence Rule and Draft Generic Environmental Impact Statement AGENCY: Nuclear Regulatory Commission... rescheduled to November 12 the Waste Confidence public meeting it initially planned to hold in Oak Brook... reactor's licensed life for operation and prior to ultimate disposal (the proposed Waste Confidence rule...

  16. 76 FR 17973 - Self-Regulatory Organizations; C2 Options Exchange, Incorporated; Order Approving Proposed Rule...

    Science.gov (United States)

    2011-03-31

    ...\\ and Rule 19b-4 thereunder,\\2\\ a proposed rule change to modify its governance structure. On February 9... Directors may establish an Advisory Board; and (3) eliminate the C2 Audit Committee. A. Elimination of the... C2 Nominating and Governance Committee would recommend the members of any Advisory Board for approval...

  17. 75 FR 65693 - Self-Regulatory Organizations; Notice of Filing and Immediate Effectiveness of Proposed Rule...

    Science.gov (United States)

    2010-10-26

    ... Exchange has observed the popularity of $0.50 strikes. The open interest in the $2.50 August strike series... Commission may designate, it has become effective pursuant to Section 19(b)(3)(A) of the Act \\9\\ and Rule 19b... are filed with the Commission, and all written communications relating to the proposed rule change...

  18. 77 FR 65754 - Self-Regulatory Organizations; C2 Options Exchange, Incorporated; Order Approving Proposed Rule...

    Science.gov (United States)

    2012-10-30

    ...,\\2\\ a proposed rule change to modify C2 Rule 6.13(c), ``Process for Complex Order RFR Auction,'' to: (i) Include the side of the market in the request for response (``RFR'') message sent to Participants at the start of a Complex Order Auction (``COA''); and (ii) require responses to an RFR message...

  19. 77 FR 3531 - Self-Regulatory Organizations; The Depository Trust Company; Order Approving Proposed Rule Change...

    Science.gov (United States)

    2012-01-24

    ... Organizations; The Depository Trust Company; Order Approving Proposed Rule Change To Enhance Risk Management.... Description The rule change will enhance the risk management controls associated with DTC's Receiver... settle in same-day funds subject to the net debit cap control\\6\\ and collateral controls\\7\\. Any DO that...

  20. 75 FR 57813 - Proposed Supplementary Rules on Public Land, Idaho

    Science.gov (United States)

    2010-09-22

    ... percent of alcohol by weight, and addresses prohibition of open containers of beer in motor vehicles... containers, including beer or wine containers, while operating or as a passenger in or on either a vehicle or... proposing to prohibit the possession of an open alcoholic beverage container by operators or passengers in...

  1. Medicare depreciation; useful life guidelines--HCFA. Proposed rule.

    Science.gov (United States)

    1982-09-30

    We are proposing to amend Medicare regulations to clarify which useful life guidelines providers of health care services may use to determine the useful life of a depreciable asset for Medicare reimbursement purposes. Current regulations state that providers must utilize HHS useful life guidelines or, if none have been published by HHS, the American Hospital Association (AHA) useful life guidelines of 1973 or IRS guidelines. We are proposing to eliminate the reference to IRS guidelines because those previously acceptable for Medicare purposes are outdated and have been made obsolete by the IRS or by statutory change. We would also delete the specific reference to the 1973 AHA guidelines. In addition, we intend this amendment to clarify that certain tax legislation on accelerated depreciation, recently passed by Congress, does not apply to the Medicare program.

  2. 76 FR 69774 - Self-Regulatory Organizations; NYSE Amex LLC; Notice of Filing of Rule Change Proposing a One...

    Science.gov (United States)

    2011-11-09

    ... Rule Change The Exchange proposes a one-year pilot program that would add new NYSE Amex Equities Rule... a one-year pilot program that would add new NYSE Amex Equities Rule 107C to establish a Retail...-Regulatory Organizations; NYSE Amex LLC; Notice of Filing of Rule Change Proposing a One-Year Pilot Program...

  3. 78 FR 76358 - Self-Regulatory Organizations; ICE Clear Credit LLC; Notice of Withdrawal of Proposed Rule Change...

    Science.gov (United States)

    2013-12-17

    ... Organizations; ICE Clear Credit LLC; Notice of Withdrawal of Proposed Rule Change To Add Rules Related to the Clearing of MCDX Index CDS Contracts and Make Conforming Changes to Existing Rules December 11, 2013. On... thereunder,\\2\\ a proposed rule change relating to the clearing of MCDX Index CDS Contracts and making...

  4. 78 FR 36616 - Self-Regulatory Organizations; The Depository Trust Company; Order Approving Proposed Rule Change...

    Science.gov (United States)

    2013-06-18

    ... of this proposed rule change filing, the United Kingdom, Mexico, Ireland, Switzerland, Spain, Norway... services industry already contain provisions allocating the risk of any FATCA Withholding tax that will...

  5. 75 FR 4451 - Financial Management Service; Proposed Collection of Information: Final Rule-Management of...

    Science.gov (United States)

    2010-01-27

    ... DEPARTMENT OF THE TREASURY Fiscal Service Financial Management Service; Proposed Collection of Information: Final Rule--Management of Federal Agency Disbursements. AGENCY: Financial Management Service, Fiscal Service, Treasury. ACTION: Notice and Request for comments. SUMMARY: The Financial Management...

  6. 76 FR 20773 - Self-Regulatory Organizations; Notice of Filing and Immediate Effectiveness of Proposed Rule...

    Science.gov (United States)

    2011-04-13

    ... Floor in violation of Rule 1080(o). The Exchange's proposal addresses the mechanics of executing the... interest and appropriate for the protection of investors and the maintenance of fair and orderly markets to...

  7. 77 FR 22827 - Self-Regulatory Organizations; Fixed Income Clearing Corporation; Order Approving Proposed Rule...

    Science.gov (United States)

    2012-04-17

    ... this sentence is incorrectly stated because FICC pays interest to those who were debited forward mark... practices and provide transparency in its processes, the Commission believes that the proposed rule change...

  8. 76 FR 62883 - Self-Regulatory Organizations; Options Clearing Corporation; Notice of Filing of Proposed Rule...

    Science.gov (United States)

    2011-10-11

    .... Self-Regulatory Organization's Statement of the Terms of Substance of the Proposed Rule Change The... that measures the implied volatility of options on the iShares Silver Trust, an exchange-traded fund...

  9. 75 FR 5363 - Self-Regulatory Organizations; NYSE Arca, Inc.; Order Approving Proposed Rule Change Modifying...

    Science.gov (United States)

    2010-02-02

    ... Realtime Reference Prices Service January 22, 2010. I. Introduction On December 1, 2009, NYSE Arca, Inc... thereunder,\\2\\ a proposed rule change to add data elements to its ``NYSE Arca Realtime Reference Prices.... Description of the Proposal The Exchange proposes several changes to the NYSE Arca Realtime Reference Prices...

  10. NRC proposes changes to nuke decommissioning funding rules

    International Nuclear Information System (INIS)

    Anon.

    1993-01-01

    The Nuclear Regulatory Commission (NRC) has proposed to amend its regulations to allow self-guarantee as a means of assuring adequate funding for nuclear plant decommissioning. It acted in response to a rulemaking petition filed by General Electric Co. and Westinghouse Electric Corp. The proposal would allow self-guarantees if certain conditions are met: Tangible net worth of at least $1 billion; Tangible net worth at least 10 times the present decommissioning cost estimate for all activities the utility is responsible for as a self-guaranteeing licensee and as parent guarantor; Domestic assets amounting to at least 90 percent of total assets or at least 10 times the present decommissioning cost estimate; A credit rating for the utility's most recent bond issuance of AAA, AA, or A (Standard ampersand Poor's), or Aaa, Aa, or A (Moody's). Additional requirements include that the utility licensee must have at least one class of equity securities registered under the Securities Exchange Act of 1934, and that an independent auditor must verify that the utility met the financial test. A utility also would be responsible for reporting any change in circumstances affecting the criteria used to meet the financial test, and would be responsible for meeting that test within 90 days of each financial year. The NRC will accept written comments until March 29, 1993

  11. 76 FR 75570 - Self-Regulatory Organizations; The Depository Trust Company; Notice of Filing of Proposed Rule...

    Science.gov (United States)

    2011-12-02

    ... Organizations; The Depository Trust Company; Notice of Filing of Proposed Rule Change To Enhance Risk Management... Proposed Rule Change The proposed rule change would enhance the risk management controls associated with... cap control \\5\\ and collateral controls.\\6\\ Any DO that obligated a Participant to pay $15 million or...

  12. 75 FR 12325 - Self-Regulatory Organizations; Notice of Filing and Immediate Effectiveness of Proposed Rule...

    Science.gov (United States)

    2010-03-15

    ... LLC To Increase the Monthly ATP Fee for All Options Market Makers and To Reduce the Per- Contract... Exchange Commission (the ``Commission'') the proposed rule change as described in Items I, II, and III... Amex Trading Permit (``ATP'') for options Market Makers. Effective March 1, 2010 the Exchange proposes...

  13. 76 FR 36947 - Self-Regulatory Organizations; The NASDAQ Stock Market LLC; Order Disapproving Proposed Rule...

    Science.gov (United States)

    2011-06-23

    ...\\ See proposed Nasdaq IM-5101-3(e). Under the proposed rule language, the facility ``should provide... its approval order, the Commission noted that the gold spot market is extremely deep and liquid, and... for the Gold Shares agreed to provide on its public Web site continuously updated information, from an...

  14. 77 FR 74449 - Water Quality Standards for the State of Florida's Lakes and Flowing Waters; Proposed Rule; Stay

    Science.gov (United States)

    2012-12-14

    ... Water Quality Standards for the State of Florida's Lakes and Flowing Waters; Proposed Rule; Stay AGENCY... State of Florida's Lakes and Flowing Waters; Final Rule'' (inland waters rule) to November 15, 2013. EPA's inland waters rule currently includes an effective date of January 6, 2013, for the entire...

  15. Overview of DOE proposed loss-of-coolant accident (LOCA) rule-revision study

    International Nuclear Information System (INIS)

    Hanson, D.J.; Batt, D.L.

    1982-01-01

    In 1981, an independent review group, a subcommittee of the President's Nuclear Oversight Committee, recognized the conservatism in particular features of the LOCA rule and recommended that research data be explicitly included in the licensing process. Also, an initial review indicated that a generic study, which is the subject of this paper, should be performed which will use research data to provide the basis for proposed revisions to the LOCA rule. The objective of this study is to develop and propose revisions to the current LOCA rule that will provide a defensible technical base upon which a more realistic assessment of safety issues can be made. From this proposed new rule, potential reductions in costs can be effected while maintaining the current level of safety. A survey of three NSSS Vendors, 14 utilities, and several other industry-related organizations was conducted to assess the industry interest, attitudes, and ideas regarding changing the LOCA rule. The survey indicated there would be benefits in having a revised LOCA rule

  16. 75 FR 39084 - Self-Regulatory Organizations; EDGX Exchange, Inc.; Notice of Filing of Proposed Rule Change To...

    Science.gov (United States)

    2010-07-07

    ... underlying assets such as futures contracts, commodities, and currency without actually trading futures or... Amend EDGX Rule 11.14, Entitled ``Trading Halts Due to Extraordinary Volatility.'' June 30, 2010... of the Proposed Rule Change The Exchange is proposing to amend EDGX Rule 11.14, entitled ``Trading...

  17. 75 FR 39074 - Self-Regulatory Organizations; EDGA Exchange, Inc.; Notice of Filing of Proposed Rule Change To...

    Science.gov (United States)

    2010-07-07

    ... underlying assets such as futures contracts, commodities, and currency without actually trading futures or... Amend EDGA Rule 11.14, Entitled ``Trading Halts Due to Extraordinary Volatility'' June 30, 2010... of the Proposed Rule Change The Exchange is proposing to amend EDGA Rule 11.14, entitled ``Trading...

  18. 75 FR 77923 - Self-Regulatory Organizations; Notice of Filing of Proposed Rule Change by NYSE Amex LLC Amending...

    Science.gov (United States)

    2010-12-14

    ... Change The Exchange proposes to amend its rules regarding the listing of $1 strike prices. The text of...-Regulatory Organizations; Notice of Filing of Proposed Rule Change by NYSE Amex LLC Amending Its Rules Regarding the Listing of Options Series With $1 Strike Prices December 8, 2010. Pursuant to Section 19(b)(1...

  19. 75 FR 77689 - Self-Regulatory Organizations; Notice of Filing of Proposed Rule Change by NYSE Arca, Inc...

    Science.gov (United States)

    2010-12-13

    ... Change The Exchange proposes to amend its rules regarding the listing of $1 strike prices. The text of...-Regulatory Organizations; Notice of Filing of Proposed Rule Change by NYSE Arca, Inc. Amending Its Rules Regarding the Listing of Option Series With $1 Strike Prices December 8, 2010. Pursuant to Section 19(b)(1...

  20. Heart Health Risk Assessment System: A Nonintrusive Proposal Using Ontologies and Expert Rules

    Directory of Open Access Journals (Sweden)

    Teresa Garcia-Valverde

    2014-01-01

    Full Text Available According to the World Health Organization, the world’s leading cause of death is heart disease, with nearly two million deaths per year. Although some factors are not possible to change, there are some keys that help to prevent heart diseases. One of the most important keys is to keep an active daily life, with moderate exercise. However, deciding what a moderate exercise is or when a slightly abnormal heart rate value is a risk depends on the person and the activity. In this paper we propose a context-aware system that is able to determine the activity the person is performing in an unobtrusive way. Then, we have defined ontology to represent the available knowledge about the person (biometric data, fitness status, medical information, etc. and her current activity (level of intensity, heart rate recommended for that activity, etc.. With such knowledge, a set of expert rules based on this ontology are involved in a reasoning process to infer levels of alerts or suggestions for the users when the intensity of the activity is detected as dangerous for her health. We show how this approach can be accomplished by using only everyday devices such as a smartphone and a smartwatch.

  1. Review of the Staff Rules and Regulations - Proposed modifications to the 10th edition

    CERN Document Server

    2006-01-01

    In accordance with the provisions of CERN/2567, CERN/FC/4824, a complete review of CERN's Staff Rules and Regulations is currently taking place, with a twofold aim: - to adapt the Organization's statutory provisions to the results of the Five-Yearly Review; - to update the Staff Rules and Regulations, which were last reviewed in full in 1996, in other areas and, wherever possible, to make them more consistent and better suited to the Organization's needs. This document contains a first set of proposed amendments, i.e. to the Preamble as well as to the first two Chapters of the Staff Rules and Regulations. These proposed amendments were examined by the Standing Concertation Committee (SCC) on 13 and 20 September 2006 and by the Tripartite Employment Conditions Forum (TREF) on 4 and 5 October 2006.

  2. 78 FR 33456 - Self-Regulatory Organizations; Fixed Income Clearing Corporation; Notice of Filing Proposed Rule...

    Science.gov (United States)

    2013-06-04

    ... certain locked- in trade sources in the future based on volumes and processing costs. \\9\\ Designated...-Regulatory Organizations; Fixed Income Clearing Corporation; Notice of Filing Proposed Rule Change to Include trueEX LLC as a Designated Locked-In Trade Source Pursuant to the Rulebook of the Government Securities...

  3. 75 FR 70665 - Proposed Significant New Use Rule for Cobalt Lithium Manganese Nickel Oxide

    Science.gov (United States)

    2010-11-18

    ... Proposed Significant New Use Rule for Cobalt Lithium Manganese Nickel Oxide AGENCY: Environmental... as cobalt lithium manganese nickel oxide (CAS No. 182442-95-1) which was the subject of... section 5(a)(2) of TSCA for the chemical substance identified as cobalt lithium manganese nickel oxide...

  4. 78 FR 6762 - Food and Drug Administration Food Safety Modernization Act: Proposed Rules To Establish Standards...

    Science.gov (United States)

    2013-01-31

    ... AGENCY: Food and Drug Administration, HHS. ACTION: Notification of public meeting. SUMMARY: The Food and Drug Administration (FDA) is announcing a public meeting to discuss the proposed rules to establish... DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration 21 CFR Parts 1, 16, 106, 110...

  5. 75 FR 11210 - Public Company Accounting Oversight Board; Order Approving Proposed Amendment to Board Rules...

    Science.gov (United States)

    2010-03-10

    ... the target threshold for U.S. market capitalization for 2009. The PCAOB was unable to conduct the... the U.S. market capitalization of the aforementioned 49 firms' issuer audit clients. The proposed rule... jurisdictions have or soon will have a local auditor oversight authority with which the Board would seek to work...

  6. 76 FR 61438 - Self-Regulatory Organizations; International Securities Exchange, LLC; Notice of Proposed Rule...

    Science.gov (United States)

    2011-10-04

    ... Organizations; International Securities Exchange, LLC; Notice of Proposed Rule Change Related to Trading Halts Due to Extraordinary Market Volatility September 28, 2011. Pursuant to Section 19(b)(1) of the... September 27, 2011, the International Securities Exchange, LLC (``Exchange'' or ``ISE'') filed with the...

  7. 76 FR 71411 - Self-Regulatory Organizations; BATS Exchange, Inc.; Order Approving Proposed Rule Change, as...

    Science.gov (United States)

    2011-11-17

    ... (the ``IPO''). The proposed rule change was published for comment in the Federal Register on September... Commission to register shares of Class A common stock and to disclose its intention to conduct an IPO offering those shares and to list those shares for trading on the Exchange. In connection with its IPO, the...

  8. 78 FR 3489 - Self-Regulatory Organizations; BATS Exchange, Inc.; Order Granting Approval of Proposed Rule...

    Science.gov (United States)

    2013-01-16

    ...-Regulatory Organizations; BATS Exchange, Inc.; Order Granting Approval of Proposed Rule Change to Amend BATS... current one-month price change is greater than or equal to the exponential weighted average of the past... price change is less than the exponential weighted average of the past seven monthly price inputs...

  9. 78 FR 59994 - Self-Regulatory Organizations; The Options Clearing Corporation; Order Approving Proposed Rule...

    Science.gov (United States)

    2013-09-30

    ... COMMISSION Self-Regulatory Organizations; The Options Clearing Corporation; Order Approving Proposed Rule... Regarding Public Directors and the Process for Designating Membership/Risk Committee Members September 24, 2013. I. Introduction On August 2, 2013, The Options Clearing Corporation (``OCC'') filed with the...

  10. 75 FR 35871 - Self-Regulatory Organizations; Notice of Filing and Immediate Effectiveness of Proposed Rule...

    Science.gov (United States)

    2010-06-23

    ... PHLX, Inc. To List Options on Trust Issued Receipts in $1 Strike Intervals June 15, 2010. Pursuant to... to list options on Trust Issued Receipts in $1 strike price intervals. The text of the proposed rule... additional text to Commentary .05(a)(vi) to allow the Exchange to list options on the Trust Issued Receipts...

  11. 75 FR 39720 - Self-Regulatory Organizations; Notice of Filing and Immediate Effectiveness of Proposed Rule...

    Science.gov (United States)

    2010-07-12

    ..., Inc. To List Options on Trust Issued Receipts in $1 Strike Intervals July 6, 2010. Pursuant to Section... strike price intervals for options on Trust Issued Receipts. The text of the proposed rule change is... strike price intervals for options on Trust Issued Receipts (``TIRs''), including Holding Company...

  12. 75 FR 40011 - Self-Regulatory Organizations; Notice of Filing and Immediate Effectiveness of Proposed Rule...

    Science.gov (United States)

    2010-07-13

    ... LLC To List Options on Trust Issued Receipts in $1 Strike Intervals July 6, 2010. Pursuant to section... strike price intervals for options on Trust Issued Receipts. The text of the proposed rule change is... establish strike price intervals for options on Trust Issued Receipts (``TIRs''), including Holding Company...

  13. 75 FR 35113 - Self-Regulatory Organizations; Notice of Filing and Immediate Effectiveness of Proposed Rule...

    Science.gov (United States)

    2010-06-21

    ... Stock Market LLC To List Options on Trust Issued Receipts in $1 Strike Intervals June 15, 2010. Pursuant... options on Trust Issued Receipts in $1 strike price intervals. The text of the proposed rule change is... options on the Trust Issued Receipts (``TIRs''), including HOLding Company Depository ReceiptS (``HOLDRS...

  14. 75 FR 3509 - Public Company Accounting Oversight Board; Order Approving Proposed Rules on Auditing Standard No...

    Science.gov (United States)

    2010-01-21

    ... Accounting Oversight Board; Order Approving Proposed Rules on Auditing Standard No. 7, Engagement Quality... standards for public company audits, including a requirement for each registered public accounting firm to... Accounting Oversight Board (the ``Board'' or the ``PCAOB'') filed with the Securities and Exchange Commission...

  15. 78 FR 68872 - Public Company Accounting Oversight Board; Notice of Filing of Proposed Rules on Auditing...

    Science.gov (United States)

    2013-11-15

    ... Accounting Oversight Board; Notice of Filing of Proposed Rules on Auditing Standard No. 17, Auditing... Public Company Accounting Oversight Board (``PCAOB'') standards. \\1\\ Terms defined in Appendix A... this standard has the same meaning as the term ``affiliates of the accounting firm'' as defined in...

  16. 75 FR 82417 - Public Company Accounting Oversight Board; Order Approving Proposed Rules on Auditing Standards...

    Science.gov (United States)

    2010-12-30

    ... Accounting Oversight Board; Order Approving Proposed Rules on Auditing Standards Related to the Auditor's Assessment of and Response to Risk and Related Amendments to PCAOB Standards December 23, 2010. I. Introduction On September 15, 2010, the Public Company Accounting Oversight Board (the ``Board'' or the ``PCAOB...

  17. 78 FR 18384 - Self-Regulatory Organizations; BATS Exchange, Inc.; Order Approving Proposed Rule Change To...

    Science.gov (United States)

    2013-03-26

    ... time by 10 total minutes, from 9:25 a.m. to 4:05 p.m.\\4\\ \\4\\ See proposed Exchange Rule 11.8.02(g)(1... designed, among other things, to promote just and equitable principles of trade, to remove impediments to... market size and could lead to tighter spreads. Finally, the Commission believes the extended time period...

  18. 77 FR 42327 - Proposed Supplementary Rules for the Morley Nelson Snake River Birds of Prey National...

    Science.gov (United States)

    2012-07-18

    ... DEPARTMENT OF THE INTERIOR Bureau of Land Management [LLIDB00100 LF1000000.HT0000 LXSS020D0000... Conservation Area AGENCY: Bureau of Land Management, Interior. ACTION: Proposed supplementary rules. SUMMARY... Canyon and within \\1/4\\ mile of the canyon rim eliminates the adverse effects to early cabin architecture...

  19. 77 FR 66196 - Self-Regulatory Organizations; Options Clearing Corporation; Order Approving Proposed Rule Change...

    Science.gov (United States)

    2012-11-02

    ... Accounting Principles (``GAAP''). Canadian clearing members that use Form 1 report the same, and in some... Organizations; Options Clearing Corporation; Order Approving Proposed Rule Change Relating to Financial... financial reporting by Canadian clearing members to reflect the Investment Industry Regulatory Organization...

  20. 78 FR 46563 - Endangered and Threatened Species: Proposed Rule To Designate Critical Habitat for the Northwest...

    Science.gov (United States)

    2013-08-01

    ... DEPARTMENT OF COMMERCE National Oceanic and Atmospheric Administration 50 CFR Part 226 [Docket No. 130513467-3467-01] RIN 0648-BD27 Endangered and Threatened Species: Proposed Rule To Designate Critical Habitat for the Northwest Atlantic Ocean Loggerhead Sea Turtle Distinct Population Segment (DPS) and...

  1. 75 FR 2573 - Self-Regulatory Organizations; Notice of Filing and Immediate Effectiveness of Proposed Rule...

    Science.gov (United States)

    2010-01-15

    ... utilizing unique and separate mnemonics specifically dedicated to SLP trading activity; (2) Adequate trading... proposed Rule). An SLP must use its SLP mnemonic when trading as an SLP in its assigned securities in order... and rebate credit will be measured only by using the SLP's unique mnemonics specifically designated...

  2. 76 FR 20910 - Proposed Approval of Air Quality Implementation Plans; Indiana; Stage I Vapor Recovery Rule

    Science.gov (United States)

    2011-04-14

    ... Engineer, Criteria Pollutant Section, Air Programs Branch (AR-18J), Environmental Protection Agency, Region... ENVIRONMENTAL PROTECTION AGENCY 40 CFR Part 52 [EPA-R05-OAR-2010-0545; FRL-9295-2] Proposed Approval of Air Quality Implementation Plans; Indiana; Stage I Vapor Recovery Rule AGENCY: Environmental...

  3. 75 FR 20018 - Self-Regulatory Organizations; BATS Exchange, Inc.; Order Approving a Proposed Rule Change, As...

    Science.gov (United States)

    2010-04-16

    ... providing such data. The proposed cost of user-accessible BATS Historical TOP Data, BATS Historical PITCH... change. The proposed rule change, as modified by Amendment No. 1, was published for comment in the... order approves the proposed rule change, as modified by Amendment Nos. 1 and 2. \\1\\ 15 U.S.C. 78s(b)(1...

  4. New security measures are proposed for N-plants: Insider Rule package is issued by NRC

    International Nuclear Information System (INIS)

    Anon.

    1984-01-01

    New rules proposed by the Nuclear Regulatory Commission (NRC) will require background investigations and psychological assessments of new job candidates and continual monitoring of the behavior of all power plant workers with access to sensitive areas. Licensees will have to submit an ''access authorization'' program for approval describing how they will conduct these security activities. The employee checks will go back five years to examine credit, educational, and criminal histories. Implementation of the rules could involve the Edison Electric Institute as an intermediary to funnel criminal checks from the Justice Department and FBI. The NRC is also considering a clarification of areas designated as ''vital'' because current designations may be too strict

  5. 75 FR 59311 - Self-Regulatory Organizations; The NASDAQ Stock Market LLC; Notice of Filing of a Proposed Rule...

    Science.gov (United States)

    2010-09-27

    ... COMMISSION Self-Regulatory Organizations; The NASDAQ Stock Market LLC; Notice of Filing of a Proposed Rule... hereby given that on September 17, 2010, The NASDAQ Stock Market LLC (``Nasdaq'' or the ``Exchange... market hours when stock pause triggers are not in effect under Rule 4120(a)(11) (or comparable rule of...

  6. 75 FR 64767 - Self-Regulatory Organizations; BATS Y-Exchange, Inc.; Notice of Filing of Proposed Rule Change To...

    Science.gov (United States)

    2010-10-20

    ...-Regulatory Organizations; BATS Y-Exchange, Inc.; Notice of Filing of Proposed Rule Change To Amend BATS Y-Exchange Rules To Conform to the Current Rules of BATS Exchange October 13, 2010. Pursuant to Section 19(b... hereby given that on October 4, 2010, BATS Y-Exchange, Inc. (the ``Exchange'' or ``BYX'') filed with the...

  7. 75 FR 70331 - Self-Regulatory Organizations; NASDAQ OMX PHLX LLC; Notice of Filing of Proposed Rule Change To...

    Science.gov (United States)

    2010-11-17

    ... standards, administrative responsibilities, and trade correction and exemptive relief data. Rule 515, like... results for all questionnaires. The Exchange has found that such questionnaires, being wholly subjective... proposes to consolidate Rules 511 and 515 into Rule 511 and to adopt for specialist units \\10\\ an objective...

  8. 75 FR 51863 - Self-Regulatory Organizations; NYSE Arca, Inc.; Order Approving Proposed Rule Change Relating to...

    Science.gov (United States)

    2010-08-23

    ...-Regulatory Organizations; NYSE Arca, Inc.; Order Approving Proposed Rule Change Relating to Listing of the... generic listing standards under NYSE Arca Equities Rule 5.2(j)(3); (ii) the continued listing standards... approving the generic listing rules applicable to the listing and trading of Units.\\9\\ \\6\\ Commentary .01(a...

  9. 77 FR 20087 - Self-Regulatory Organizations; NYSE Arca, Inc.; Order Granting Approval of Proposed Rule Change...

    Science.gov (United States)

    2012-04-03

    ... Inflation-Linked Bond Strategy Fund (``Fund'') under NYSE Arca Equities Rule 8.600. The proposed rule change... Listing and Trading of the PIMCO Global Advantage Inflation-Linked Bond Strategy Fund Under NYSE Arca Equities Rule 8.600 March 28, 2012. I. Introduction On January 27, 2012, NYSE Arca, Inc. (``Exchange'' or...

  10. Suicide prevention: A proposed national strategy for South Africa ...

    African Journals Online (AJOL)

    Suicidal behaviour is an important public health problem globally and in Africa. A brief overview of the nature and severity of the problem is provided, but the primary aim of this paper is to identify priorities and prevention strategies for reducing suicidal behaviour in South Africa by discussing a framework for a proposed ...

  11. Supplemental Nutrition Assistance Program: Nutrition Education and Obesity Prevention Grant Program. Final rule.

    Science.gov (United States)

    2016-03-31

    This rule adopts the interim rule implementing the Supplemental Nutrition Assistance Program (SNAP) nutrition education and obesity prevention grant program with changes as provided in this rule. This rule also amends SNAP regulations to implement section 28 of the Food and Nutrition Act (FNA) of 2008, as added by section 241 of the Healthy, Hunger-Free Kids Act (HHFKA) of 2010, to award grants to States for provision of nutrition education and obesity prevention programs. These programs provide services for eligible individuals that promote healthy food choices consistent with the current Dietary Guidelines for Americans (DGAs). The rule provides State agencies with requirements for implementing section 28, including the grant award process and describes the process for allocating the Federal grant funding for each State's approved SNAP-Ed plan authorized under the FNA to carry out nutrition education and obesity prevention services each fiscal year. This final rule also implements section 4028 of the Agricultural Act of 2014 (Farm Bill of 2014), which authorizes physical activity promotion in addition to promotion of healthy food choices as part of this nutrition education and obesity prevention program.

  12. Proposed amendments to the tenth edition of the staff rules and regulations

    CERN Document Server

    1999-01-01

    The implementation of the tenth edition of the Staff Rules and Regulations on 1st January 1996 has highlighted the need for certain drafting amendments, now presented in this document. These initial proposed amendments are presented independently of any changes which might arise from the five-yearly review of the financial conditions of the members of the personnel currently in progress. In accordance with Articles VII 1.07 and 1.08 of the Staff Rules, the proposals set out below have been the subject of discussion within the Standing Concertation Committee. These modifications to the Staff Regulations have been discussed in TREF at its twenty-eighth and twenty-ninth meetings. They are submitted by the Management to Finance Committee for examination and approval, to take effect on 1st January 2000.

  13. 76 FR 67784 - Self-Regulatory Organizations; BATS Y-Exchange, Inc.; Order Approving Proposed Rule Change To...

    Science.gov (United States)

    2011-11-02

    ... Stock (the ``IPO''). The proposed rule change was published for comment in the Federal Register on... intention to conduct its IPO and to list those shares for trading on the Exchange. In connection with its IPO, the Exchange filed this proposed rule change to amend and restate the Corporation's current...

  14. 78 FR 62884 - Self-Regulatory Organizations; NASDAQ OMX BX, Inc.; Order Approving a Proposed Rule Change To...

    Science.gov (United States)

    2013-10-22

    ... the regulatory services agreement in effect at the time of its ] acquisition must continue to be... Commission has considered the proposed rule's impact on efficiency, competition, and capital formation. See... the instant proposed rule change. In the Notice, the Exchange further represents that it will continue...

  15. 75 FR 17820 - Self-Regulatory Organizations; Notice of Filing and Immediate Effectiveness of a Proposed Rule...

    Science.gov (United States)

    2010-04-07

    ... Statement of the Terms of Substance of the Proposed Rule Change The Exchange is filing with the Commission a proposal to amend: Phlx Rule 1101A (Terms of Options Contracts) regarding listing options on the NASDAQ... 1107A (NASDAQ OMX Group, Inc. Indexes) regarding disclaimer of express or implied warranties in respect...

  16. 78 FR 17255 - Self-Regulatory Organizations; NASDAQ OMX BX, Inc.; Notice of Filing of Proposed Rule Change to...

    Science.gov (United States)

    2013-03-20

    ... Extraordinary Market Volatility. The text of the proposed rule change is below; proposed new language is in... option where the bid price is $0.00. Series of options quoted zero bid are usually deep out-of-the-money... Commission's Internet Web site ( http://www.sec.gov/rules/sro.shtml ). Copies of the submission, all...

  17. 76 FR 34781 - Self-Regulatory Organizations; The NASDAQ Stock Market LLC; Notice of Filing of Proposed Rule...

    Science.gov (United States)

    2011-06-14

    ... income statement, which must be presented in English, and is filed no later than six months following the..., consistent with Rule 5250(c)(2), it includes an interim balance sheet and income statement, which must be... Organization's Statement of the Terms of the Substance of the Proposed Rule Change Nasdaq proposes to adopt...

  18. 78 FR 1906 - Self-Regulatory Organizations; NASDAQ OX PHLX LLC; Order Approving Proposed Rule Change To Amend...

    Science.gov (United States)

    2013-01-09

    ... COMMISSION Self-Regulatory Organizations; NASDAQ OX PHLX LLC; Order Approving Proposed Rule Change To Amend...), competition among market makers, observance of ethical standards, and administrative factors. Specifically... Commission has considered the proposed rule's impact on efficiency, competition and capital formation. See 15...

  19. 76 FR 805 - Self-Regulatory Organizations; NYSE Arca, Inc.; Notice of Filing of Proposed Rule Change Relating...

    Science.gov (United States)

    2011-01-06

    ... Trading Shares of the SPDR Nuveen S&P High Yield Municipal Bond ETF December 30, 2010. Pursuant to Section... Change The Exchange proposes to list and trade shares of the SPDR Nuveen S&P High Yield Municipal Bond ETF under NYSE Arca Equities Rule 5.2(j)(3), Commentary .02. The text of the proposed rule change is...

  20. Analysis of public comments on the proposed rule on nuclear power plant license renewal

    International Nuclear Information System (INIS)

    1991-12-01

    This report provides a summary and analysis of public comments on the proposed license renewal rule for the nuclear power plants (10 CFR Part 54) published in the Federal Register on 17 July 1990. It also documents the NRC's resolution of the issues raised by the commenters. Comments from 121 organizations and 76 individuals were reviewed and analyzed to identify the issues, including those pertaining to the adequacy of the licensing basis, the performance of an integrated plant assessment, backfit considerations, and need for public hearings. The analysis included grouping of commenters' views according to the issues raised. The public comments analyzed in this report were taken into consideration in the development of the final rule and revisions to the supporting documents

  1. Citizens United, public health, and democracy: the Supreme Court ruling, its implications, and proposed action.

    Science.gov (United States)

    Wiist, William H

    2011-07-01

    The 2010 US Supreme Court Citizens United v Federal Election Commission 130 US 876 (2010) case concerned the plans of a nonprofit organization to distribute a film about presidential candidate Hillary Clinton. The Court ruled that prohibiting corporate independent expenditures for advocacy advertising during election campaigns unconstitutionally inhibits free speech. Corporations can now make unlimited contributions to election advocacy advertising directly from the corporate treasury. Candidates who favor public health positions may be subjected to corporate opposition advertising. Citizen groups and legislators have proposed remedies to ameliorate the effects of the Court's ruling. The public health field needs to apply its expertise, in collaboration with others, to work to reduce the disproportionate influence of corporate political speech on health policy and democracy.

  2. [Serious accidents caused by horses. Warnings and prevention rules].

    Science.gov (United States)

    Muñiz Fontán, M; Moure González, J D; Mirás Veiga, A; Rodríguez Núñez, A

    2009-05-01

    Children's equestrian activities in the domestic, play activities, sports and educational areas are relatively frequent, and are not exempt from risks. Nevertheless, there is a lack of data on horse-related injuries, their circumstances and the key points for their prevention. Retrospective and descriptive study of pediatric equestrian injuries admitted to Hospital between July 1997 and September 2008. A total of 17 patients with ages between 4 and 17 years were analyzed. There were 14 accidental falls, 2 kicks and 1 bite, and 8 patients had lost consciousness after the accident. Only 1 patient used a protective helmet. There were 3 skull fractures, 4 intracranial haemorrhages, 1 pneumoencephalus and 2 diffuse axonal injuries. There were also 4 long bone fractures, 1 jaw fracture, 1 vertebral wedging and 1 partial ear avulsion were recorded. A total of 8 patients required intensive care, 2 underwent neurosurgery due to an intracranial haematoma and 4 surgical fracture reduction. Horse handling by children and teenagers can be a high risk activity. In our cases brain trauma was the most common and severe injury. Due to the poor use of protection devices by our patients, we believe it is now necessary to take measures to increase safety in equestrian activities.

  3. Proposed Rule for Control of Air Pollution From New Motor Vehicles: Proposed Heavy-Duty Engine and Vehicle Standards and Highway Diesel Fuel Sulfur Control Requirements

    Science.gov (United States)

    Rule summary, CFR citations and additional resources concerning proposed new emission standards that will begin to take effect in 2007 and corresponding diesel fuel requirements that take effect in 2006.

  4. Proposed Adjustments to PI-RADS Version 2 Decision Rules: Impact on Prostate Cancer Detection.

    Science.gov (United States)

    Rosenkrantz, Andrew B; Babb, James S; Taneja, Samir S; Ream, Justin M

    2017-04-01

    Purpose To test the impact of existing Prostate Imaging Reporting and Data System (PI-RADS) version 2 (V2) decision rules, as well as of proposed adjustments to these decision rules, on detection of Gleason score (GS) 7 or greater (GS ≥7) prostate cancer. Materials and Methods Two radiologists independently provided PI-RADS V2 scores for the dominant lesion on 343 prostate magnetic resonance (MR) examinations. Diagnostic performance for GS ≥7 tumor was assessed by using MR imaging-ultrasonography fusion-targeted biopsy as the reference. The impact of existing PI-RADS V2 decision rules, as well as a series of exploratory proposed adjustments, on the frequency of GS ≥7 tumor detection, was evaluated. Results A total of 210 lesions were benign, 43 were GS 6, and 90 were GS ≥7. Lesions were GS ≥7 in 0%-4.1% of PI-RADS categories 1 and 2, 11.4%-27.1% of PI-RADS category 3, 44.4%-49.3% of PI-RADS category 4, and 72.1%-73.7% of PI-RADS category 5 lesions. PI-RADS category 4 or greater had sensitivity of 78.9%-87.8% and specificity of 75.5%-79.1 for detecting GS ≥7 tumor. The frequency of GS ≥7 tumor for existing PI-RADS V2 decision rules was 30.0%-33.3% in peripheral zone (PZ) lesions upgraded from category 3 to 4 based on dynamic contrast enhancement (DCE) score of positive; 50.0%-66.7% in transition zone (TZ) lesions upgraded from category 3 to 4 based on diffusion-weighted imaging (DWI) score of 5; and 71.7%-72.7% of lesions in both zones upgraded from category 4 to 5 based on size of 15 mm or greater. The frequency of GS ≥7 tumor for proposed adjustments to the decision rules was 30.0%-60.0% for TZ lesions upgraded from category 3 to 4 based on DWI score of 4; 33.3%-57.1% for TZ lesions upgraded from category 3 to 4 based on DCE score of positive when incorporating new criteria (unencapsulated sheetlike enhancement) for DCE score of positive in TZ; and 56.4%-61.9% for lesions in both zones upgraded from category 4 to 5 based on size of 10-14 mm. Other

  5. Request of General Electric Co. to exempt medical diagnostic equipment from the Commission's rules--Federal Communications Commission. Proposed rule.

    Science.gov (United States)

    1981-09-08

    This Notice responds to petitions from the General Electric Company and the Health Industries Manufacturers Association to exempt from the measurement, recordkeeping and labeling computing devices rules those medical devices marketed for use in hospitals.

  6. Standards to prevent, detect, and respond to sexual abuse and sexual harassment involving unaccompanied children. Interim final rule (IFR).

    Science.gov (United States)

    2014-12-24

    This IFR proposes standards and procedures to prevent, detect, and respond to sexual abuse and sexual harassment involving unaccompanied children (UCs) in ORR's care provider facilities. DATES: This IFR is effective on December 24, 2014. ORR care provider facilities must be in compliance with this IFR by June 24, 2015 but encourages care provider facilities to be in compliance sooner, if possible. HHS will work with facilities to implement and enforce the standards contained in this rule. Comments on this IFR must be received on or before February 23, 2015.

  7. 76 FR 55840 - Cape Hatteras National Seashore Proposed Rule: Off-Road Vehicle Management-Reopening of Public...

    Science.gov (United States)

    2011-09-09

    ... National Seashore Proposed Rule: Off-Road Vehicle Management--Reopening of Public Comment Period AGENCY...-road vehicle use at Cape Hatteras National Seashore in North Carolina. The additional comment period... rule to manage off-road vehicle use at Cape Hatteras National Seashore, North Carolina. (76 FR 39350...

  8. 77 FR 43618 - Self-Regulatory Organizations; The NASDAQ Stock Market LLC; Order Approving a Proposed Rule...

    Science.gov (United States)

    2012-07-25

    ...-Regulatory Organizations; The NASDAQ Stock Market LLC; Order Approving a Proposed Rule Change To Modify Its Corporate Governance Rules July 19, 2012. I. Introduction On May 17, 2012, The NASDAQ Stock Market LLC... market and a national market system and, in general, to protect investors and the public interest.\\21...

  9. 75 FR 57496 - Notice of Proposed Supplementary Rule To Require the Use of Certified Noxious-Weed-Free Forage...

    Science.gov (United States)

    2010-09-21

    ... supplementary rule that would require anyone bringing or anyone feeding or storing forage or straw on BLM... plans for noxious weeds. The proposed rules are intended to complement the existing regulatory framework... feeding, maintenance feeding, and emergency feeding on lands administered by the BLM. The stipulation...

  10. 77 FR 52096 - Self-Regulatory Organizations; EDGX Exchange, Inc.; Order Approving a Proposed Rule Change, as...

    Science.gov (United States)

    2012-08-28

    ...'s rules, the financial and regulatory risk management controls and supervisory procedures required...-Regulatory Organizations; EDGX Exchange, Inc.; Order Approving a Proposed Rule Change, as Modified by... that broker-dealers appropriately control the risks associated with market access, so as not to...

  11. 77 FR 52097 - Self-Regulatory Organizations; EDGA Exchange, Inc.; Order Approving a Proposed Rule Change, as...

    Science.gov (United States)

    2012-08-28

    ... financial and regulatory risk management controls and supervisory procedures required by Rule 15c3-5 under...-Regulatory Organizations; EDGA Exchange, Inc.; Order Approving a Proposed Rule Change, as Modified by... that broker-dealers appropriately control the risks associated with market access, so as not to...

  12. 77 FR 25770 - Self-Regulatory Organizations; NYSE Amex LLC; Notice of Filing of Proposed Rule Change Amending...

    Science.gov (United States)

    2012-05-01

    ... settings via Regulatory Bulletin. The Mechanism protects Market Makers from the risk associated with an...-Regulatory Organizations; NYSE Amex LLC; Notice of Filing of Proposed Rule Change Amending NYSE Amex Options Rule 928NY Specifying That the Potential Range for the Settings Applicable to the Market Maker Risk...

  13. 78 FR 68111 - Self-Regulatory Organizations; NYSE MKT LLC; Notice of Filing of Proposed Rule Change, as...

    Science.gov (United States)

    2013-11-13

    ... entered by ATP Holders. \\7\\ Under Rules 980NY(c)(i)-(iii), incoming orders or quotes, or those residing in... ATP Holder During the Trading Day November 6, 2013. Pursuant to Section 19(b)(1) of the Securities... (``Commission'') the proposed rule change as described in Items I, II, and III below, which Items have been...

  14. 77 FR 20869 - Self-Regulatory Organizations; NYSE Amex LLC; Order Approving a Proposed Rule Change Amending the...

    Science.gov (United States)

    2012-04-06

    ... identify all of its approved persons to the Exchange and each such approved person would continue to be... rule would have a significant effect on efficiency, competition, or capital formation. In light of the... formation and has concluded that the proposed rule is unlikely to have any significant effect.\\9\\ \\9\\ 15 U.S...

  15. 75 FR 44829 - Self-Regulatory Organizations; The NASDAQ Stock Market LLC; Order Approving a Proposed Rule...

    Science.gov (United States)

    2010-07-29

    ... Amendments No. 1 and 2 Thereto, To Amend Certain Corporate Governance Disclosure Requirements for Listed... rules relating to corporate governance standards for listed companies. The proposed rule change, as... audit, compensation, and nominating committees, and replace them with references to equivalent...

  16. 75 FR 51107 - Notice of Proposed Supplementary Rules for Public Lands in Routt County, CO: Emerald Mountain...

    Science.gov (United States)

    2010-08-18

    ... Proposed Supplementary Rules for Public Lands in Routt County, CO: Emerald Mountain Special Recreation... regulate conduct on specific public lands within Routt County, Colorado. The rules apply to the Emerald Mountain Special Recreation Management Area (SRMA), also known as Emerald Mountain. The BLM has determined...

  17. 76 FR 38226 - Self-Regulatory Organizations; NASDAQ OMX BX, Inc.; Notice of Filing of Proposed Rule Change...

    Science.gov (United States)

    2011-06-29

    ... than the proposed execution price; and (B) on the BOX Book within a depth of the BOX Book so that it... Customer Orders that are within a depth of the BOX Book so that they would otherwise trade with the Agency... prescribed within the BOX Rules. \\4\\ See, e.g., International Securities Exchange Rule 716 and Chicago Board...

  18. 78 FR 54696 - Self-Regulatory Organizations; The Depository Trust Company; Notice of Filing of Proposed Rule...

    Science.gov (United States)

    2013-09-05

    ... recovery, DTC has determined that it is not recovering its costs from usage of the Service by only a few... that the proposed rule change will have any impact, or impose any burden, on competition. (C) Self... Comments Use the Commission's Internet comment form ( http://www.sec.gov/rules/sro.shtml ); or Send an...

  19. 77 FR 29721 - Self-Regulatory Organizations; NYSE Amex LLC; Notice of Filing of Proposed Rule Change Amending...

    Science.gov (United States)

    2012-05-18

    ... NYSE Amex Options Rule 904 To Eliminate Position Limits for Options on the SPDR[supreg] S&P 500[supreg... limits for options on the SPDR[supreg] S&P 500[supreg] exchange-traded fund (``SPY ETF''),\\3\\ which list and trade under the symbol SPY. The text of the proposed rule change is available at the Exchange, the...

  20. 75 FR 55840 - Self-Regulatory Organizations; NYSE Arca, Inc.; Order Granting Approval of a Proposed Rule Change...

    Science.gov (United States)

    2010-09-14

    ... Listing and Trading of Shares of the PIMCO Build America Bond Strategy Fund September 7, 2010. I... (``Shares'') of the PIMCO Build America Bond Strategy Fund (the ``Fund'') of the PIMCO ETF Trust (the ``Trust'') under NYSE Arca Equities Rule 8.600 (Managed Fund Shares). The proposed rule change was...

  1. Conflict of Laws on Insurance Contracts in Europe : he Rome I proposal – Towards Uniform Conflict Rules for Insurance Contracts?

    NARCIS (Netherlands)

    X.E. Kramer (Xandra)

    2007-01-01

    textabstractThis contribution focuses on the conflict of law rules on insurance contracts and the proposed provision on the occasion of the establishment of the Rome I Regulation. It is concluded that the current conflict rules on insurance contracts are unclear and unsatisfactory as a result of

  2. 75 FR 6738 - Self-Regulatory Organizations; Notice of Filing and Immediate Effectiveness of Proposed Rule...

    Science.gov (United States)

    2010-02-10

    ..., to correspond to FINRA Rule 2220, Options Communications. Many elements of current NYSE Amex Rule 991... and approval process for advertisements, correspondence, and institutional sales material. The...

  3. 75 FR 6745 - Self-Regulatory Organizations; Notice of Filing and Immediate Effectiveness of Proposed Rule...

    Science.gov (United States)

    2010-02-10

    ..., to correspond to FINRA Rule 2220, Options Communications. Many elements of current NYSE Amex Rule 991... and approval process for advertisements, correspondence, and institutional sales material. The...

  4. Local Staff (LS) - Proposal by the Management, Including related Modifications to the Staff Rules And Regulations

    CERN Document Server

    2003-01-01

    The issue of Local Staff (LS) has been discussed since May 2002 at successive meetings of TREF and the Committees, leading to a proposal document by the Management, which was examined at TREF last November. As reported by the Chairman of TREF to the Finance Committee in December, the Management has now revised its proposal in the light of discussions at the Forum. This document summarises the background, the main aims, scope and features of LS, as well as estimated consequences of implementing the Management's proposal, including those indicated in the Human Resources Plan submitted last December. Related modifications of the Staff Rules and Regulations required to implement the Management's proposal are set out in Annex 8. After discussion at TREF in February 2003, the Management hereby submits its proposal for approval by the Finance Committee and the Council, for entry into force as of 1 April 2003. This time-scale would permit gradual implementation of LS starting this year, which is consistent with the f...

  5. 78 FR 26823 - Self-Regulatory Organizations; the Depository Trust Company; Notice of Filing of Proposed Rule...

    Science.gov (United States)

    2013-05-08

    ... date of this proposed rule change filing, the United Kingdom, Mexico, Ireland, Switzerland, Spain... services industry already contain provisions allocating the risk of any FATCA Withholding tax that will...

  6. 75 FR 1438 - Self-Regulatory Organizations; New York Stock Exchange LLC; Order Approving a Proposed Rule...

    Science.gov (United States)

    2010-01-11

    ... has considered the proposed rule's impact on efficiency, competition, and capital formation. See 15 U... conditions. Recent trends in market activity have driven down both average trade sizes and average stock...

  7. 77 FR 42349 - Self-Regulatory Organizations; NYSE Amex LLC; Order Approving a Proposed Rule Change Defining a...

    Science.gov (United States)

    2012-07-18

    ... ATP Holders via Regulatory Bulletin regarding the rule change. The Exchange plans to issue notice....\\7\\ \\7\\ See Notice, supra note 3, at 32158. III. Discussion The Commission finds that the proposed...

  8. 76 FR 28836 - Self-Regulatory Organizations; Notice of Filing of Proposed Rule Change by NASDAQ OMX PHLX LLC...

    Science.gov (United States)

    2011-05-18

    ... series. Second, in light of the proposed language in Rule 1101A(b) regarding opening one month and series... reference to the cycle month concept. See supra note 6. Third, the Exchange proposes to add new language in... language in subsection (b) about opening index options. The language change proposed by the Exchange in...

  9. 75 FR 1091 - Self-Regulatory Organizations; Notice of Filing and Immediate Effectiveness of Proposed Rule...

    Science.gov (United States)

    2010-01-08

    ... delete NYSE Rule 445 (Anti-Money Laundering Compliance Program) and adopt new Rule 3310 (Anti-Money..., subject to certain amendments, NASD Rule 3011 (Anti- Money Laundering Compliance Program) and related Interpretive Material NASD IM-3011-1 and 3011-2 as consolidated FINRA Rule 3310 (Anti-Money Laundering...

  10. 76 FR 20506 - Technical Amendment to Rule 19b-4: Filings With Respect to Proposed Rule Changes by Self...

    Science.gov (United States)

    2011-04-13

    ... anticipate that any competitive advantages or disadvantages would be created. List of Subjects in 17 CFR Part... that references to ``business day'' in Section 19(b) of the Exchange Act and Rule 19b-4 thereunder... business. DATES: Effective Date: April 13, 2011. FOR FURTHER INFORMATION CONTACT: Richard Holley III...

  11. 76 FR 64142 - Self-Regulatory Organizations; The NASDAQ Stock Market LLC; Notice of Filing of Proposed Rule...

    Science.gov (United States)

    2011-10-17

    ... COMMISSION Self-Regulatory Organizations; The NASDAQ Stock Market LLC; Notice of Filing of Proposed Rule... hereby given that on September 28, 2011, The NASDAQ Stock Market LLC (``NASDAQ'') filed with the... Change NASDAQ is filing with the Commission a proposal for the NASDAQ Options Market (``NOM'' or...

  12. 77 FR 61649 - Self-Regulatory Organizations; ICE Clear Credit LLC; Order Approving Proposed Rule Change To...

    Science.gov (United States)

    2012-10-10

    ..., 2012). II. Description of the Proposal The purpose of proposed rule change is to provide for the... Companies, Inc.; Pacific Gas and Electric Company; and Starwood Hotels & Resorts Worldwide, Inc. (the... Names (Starwood Hotels & Resorts Worldwide, Inc.) was recently added by Markit as one of the one hundred...

  13. 77 FR 20870 - Self-Regulatory Organizations; New York Stock Exchange LLC; Order Approving a Proposed Rule...

    Science.gov (United States)

    2012-04-06

    ... continue to be required to consent to the Exchange's jurisdiction. The Exchange also proposed to make... significant effect on efficiency, competition, or capital formation. In light of the record, the Commission has considered the proposed rule's impact on efficiency, competition, and capital formation and has...

  14. 77 FR 41829 - Self-Regulatory Organizations; BATS Exchange, Inc.; Notice of Filing of Proposed Rule Change, as...

    Science.gov (United States)

    2012-07-16

    ... From the Federal Register Online via the Government Publishing Office SECURITIES AND EXCHANGE... Modified by Amendment No. 1, To Adopt a New Market Maker Peg Order Available to Exchange Market Makers July... of the Proposed Rule Change The Exchange proposes to adopt a new Market Maker Peg Order to provide...

  15. 77 FR 41842 - Self-Regulatory Organizations; BATS Y-Exchange, Inc.; Notice of Filing of Proposed Rule Change...

    Science.gov (United States)

    2012-07-16

    ... From the Federal Register Online via the Government Publishing Office SECURITIES AND EXCHANGE... Modified by Amendment No. 1, To Adopt a New Market Maker Peg Order Available to Exchange Market Makers July... of the Proposed Rule Change The Exchange proposes to adopt a new Market Maker Peg Order to provide...

  16. 76 FR 49816 - Self-Regulatory Organizations; NASDAQ OMX PHLX LLC; Notice of Filing of Proposed Rule Change...

    Science.gov (United States)

    2011-08-11

    ... Regarding Streaming Quote Traders and Remote Streaming Quote Traders Entering Certain Option Day Limit... Commission a proposal to allow entry of day limit orders for the proprietary accounts of Streaming Quote Traders and Remote Streaming Quote Traders. The text of the proposed rule change is available on the...

  17. 75 FR 1099 - Self-Regulatory Organizations; Notice of Filing and Immediate Effectiveness of Proposed Rule...

    Science.gov (United States)

    2010-01-08

    ... Laundering Compliance Program) and adopt new Rule 3310--NYSE Amex Equities (Anti-Money Laundering Compliance... amendments, NASD Rule 3011 (Anti- Money Laundering Compliance Program) and related Interpretive Material NASD IM-3011-1 and 3011-2 as consolidated FINRA Rule 3310 (Anti-Money Laundering Compliance Program), and...

  18. Idiosyncratic drug hepatotoxicity: strategy for prevention and proposed mechanism.

    Science.gov (United States)

    Ikeda, Toshihiko

    2015-01-01

    Idiosyncratic drug toxicity has led to the market withdrawal of many drugs in the past. Since animal experiments are not predictive of such toxicity, the pharmaceutical industry continues to seek new methodologies for the prevention of such effects. Although the mechanism of idiosyncratic drug toxicity remains unclear, immune reactions are likely involved. Although drugs with low molecular weights are typically not themselves immunogenic, these drugs may become haptens after being converted to chemically reactive metabolites and becoming covalently cross-linked to proteins. Therefore, screening tests to detect chemically reactive metabolites, most typically by trapping with glutathione, are carried out at early stages of drug development. More quantitative methods are used in later stages of drug development; radioassays for covalent binding (using (14)Cor (3)H-labeled compounds) are most frequently employed. A zone classification system created by combining previous assessment criteria for the chemically reactive metabolites in vitro (assessment of drug candidates. A mechanism for idiosyncratic, drug-induced hepatotoxicity is proposed by analogy to virus-induced hepatitis, where cytotoxic T lymphocytes play an important role; we suggest that idiosyncrasy reflects the involvement of polymorphisms in the human leucocyte antigen-encoding loci. In fact, a strong correlation has been found between of idiosyncratic drug toxicity and specific human leucocyte antigen genotypes. Therefore, screening of patients for gene biomarkers is expected to reduce the clinical risk of idiosyncratic drug toxicity, thereby prolonging the life cycle of otherwise useful drugs.

  19. 77 FR 40392 - Self-Regulatory Organizations; EDGX Exchange, Inc.; Notice of Filing of Proposed Rule Changes To...

    Science.gov (United States)

    2012-07-09

    ... supervisory procedures that are reasonably designed to manage the financial, regulatory and other risks of... addition, the Market Access Rule requires certain regulatory risk management controls that, among other.... These regulatory risk management controls also include measures designed to prevent the entry of orders...

  20. FDA's proposed rules on patent listing requirements for new drug and 30-month stays on ANDA approval (proposed Oct. 24, 2002).

    Science.gov (United States)

    Hui, Yuk Fung

    2003-01-01

    In order to close the loophole in the generic drug approval process that allows a brand name drug patent holder to delay or defeat generic drug application merely by technicality, the FDA recently proposed to modify its regulations. Those proposals affect the patent listing requirements of a new drug application, and the duration of time that a generic drug application could be put on hold in the event of a patent infringement suit. With the modified rules, the FDA expects to see an increase in the availability of generic drugs, which eventually will lead to lower drug costs. Ms. Hui discusses the contents of the proposed regulations and provides an analysis of the proposed rule's legal authority, implications on patent rights, and impact on the pharmaceutical industry.

  1. Table - Impacts of the Proposed Transport Rule on Counties with Monitors Projected to have Ozone and/or Fine Particle Air Quality Problems

    Science.gov (United States)

    This table shows the impacts of the proposed Transport Rule on Counties with Monitors Projected to have Ozone and/or Fine Particle Air Quality Problems, both with and without the Cross-State Air Pollution Rule.

  2. 77 FR 9290 - Self-Regulatory Organizations; Notice of Filing and Immediate Effectiveness of Proposed Rule...

    Science.gov (United States)

    2012-02-16

    ... the exemption in NASD Rule 3020 for sole stockholders and sole proprietors. The rule change also... solely as a Designated Market Maker (``DMM''),\\10\\ floor broker or registered floor trader and does not... a one-person firm.\\11\\ Historically, a sole proprietor or sole stockholder member was excluded from...

  3. 75 FR 17816 - Self-Regulatory Organizations; Notice of Filing and Immediate Effectiveness of Proposed Rule...

    Science.gov (United States)

    2010-04-07

    ... definition shall not be applied to any other NYSE Rule and is separate and distinct from the Rule 1 definition discussed herein. Additionally, in certain instances, the Exchange's CRO is one of the named... unrest, terrorism, acts of war, or loss or interruption of facilities utilized by the Exchange, (2) a...

  4. 75 FR 54929 - Self-Regulatory Organizations; Fixed Income Clearing Corporation; Order Approving Proposed Rule...

    Science.gov (United States)

    2010-09-09

    ... (``U.S. Branches''). GSD and MBSD Rules currently classify the membership of such U.S. Branches as... their home country law with their membership application. III. Discussion The Commission finds that the... its Rules to will provide consistent treatment to all its Members that are regulated by a U.S. or...

  5. 77 FR 59227 - Self-Regulatory Organizations; BATS Exchange, Inc.; Order Granting Approval of Proposed Rule...

    Science.gov (United States)

    2012-09-26

    ... pools of mortgages. CMOs may have multiple classes with different payment rights and protections. \\13... conditions or for reasons that, in the view of the Exchange, make trading in the Shares inadvisable. \\25\\ See... subject to the provisions of Rule 204A-1 under the Advisers Act relating to codes of ethics. This Rule...

  6. 75 FR 76509 - Self-Regulatory Organizations; Notice of Filing and Immediate Effectiveness of Proposed Rule...

    Science.gov (United States)

    2010-12-08

    ... and other persons using any facility or system which the Exchange operates or controls. The impact of... national best bid and offer (i.e., its propensity to add or remove liquidity), its usage of Non-Displayed... Commission's Internet comment form ( http://www.sec.gov/rules/sro.shtml ); or Send an e-mail to rule-comments...

  7. 78 FR 42815 - Self-Regulatory Organizations; The Options Clearing Corporation; Order Approving Proposed Rule...

    Science.gov (United States)

    2013-07-17

    ... contract adjustments will retain all other functions and authority granted under the By-Laws, including...-references to By-Laws and Rules that are being amended. \\10\\ OCC's Securities Committee is empowered under...\\ the conforming and clarifying changes to OCC's By-Laws and Rules should help ensure that OCC maintains...

  8. 76 FR 12082 - U.S. Court of Appeals for the Armed Forces Proposed Rules Changes

    Science.gov (United States)

    2011-03-04

    ... the Court. (b) Any violation of this rule will be deemed a contempt of this Court and, after due... rule will be deemed a contempt of this Court and, after due notice and hearing, may be punished... Article 48, Uniform Code of Military Justice, to give express contempt power to the United States Court of...

  9. 75 FR 20401 - Self-Regulatory Organizations; NYSE Amex LLC; Notice of Filing of Proposed Rule Change, and...

    Science.gov (United States)

    2010-04-19

    ... may be examined at the places specified in Item IV below. The Exchange has prepared summaries, set... Replenishment Point (``LRP'') parameters. Trading in Nasdaq Securities will be subject to rules that are... ``QQQs'') and has proposed a set of special requirements governing the assignment of the QQQs and its...

  10. 75 FR 51861 - Self-Regulatory Organizations; The NASDAQ Stock Market LLC; Notice of Filing of Proposed Rule...

    Science.gov (United States)

    2010-08-23

    ...-2010-100] Self-Regulatory Organizations; The NASDAQ Stock Market LLC; Notice of Filing of Proposed Rule... on August 6, 2010, The NASDAQ Stock Market LLC (``NASDAQ'' or the ``Exchange'') filed with the... Acquisition of an ECN by The Nasdaq Stock Market, Inc.) and 52902 (December 7, 2005), 70 FR 73810 (December 13...

  11. 77 FR 37086 - Self-Regulatory Organizations; The NASDAQ Stock Market LLC; Notice of Filing of Proposed Rule...

    Science.gov (United States)

    2012-06-20

    ...-Regulatory Organizations; The NASDAQ Stock Market LLC; Notice of Filing of Proposed Rule Change To Adopt a... hereby given that on June 6, 2012, the NASDAQ Stock Market LLC (``NASDAQ'' or the ``Exchange'') filed... obligations, NASDAQ requires market makers for each stock in which they are registered to continuously...

  12. 78 FR 6842 - Self-Regulatory Organizations; The NASDAQ Stock Market LLC; Order Approving a Proposed Rule...

    Science.gov (United States)

    2013-01-31

    ...-Regulatory Organizations; The NASDAQ Stock Market LLC; Order Approving a Proposed Rule Change To Establish a... NASDAQ Stock Market LLC (``Exchange'' or ``NASDAQ'') filed with the Securities and Exchange Commission... optional means for clients to receive third party market data and NASDAQ TotalView ITCH market data. NASDAQ...

  13. 77 FR 19401 - Self-Regulatory Organizations; NYSE Arca, Inc.; Notice of Filing of Proposed Rule Change Amending...

    Science.gov (United States)

    2012-03-30

    .... Error positions may result from a technical or systems issue that causes orders to be executed in the... Operation of an Error Account for Arca Securities March 26, 2012. Pursuant to Section 19(b)(1) \\1\\ of the... describe the operation of an error account for Arca Securities. The text of the proposed rule change is...

  14. 77 FR 77141 - Self-Regulatory Organizations; The NASDAQ Stock Market LLC; Notice of Filing of a Proposed Rule...

    Science.gov (United States)

    2012-12-31

    ... MQP Company,\\5\\ on behalf of an MQP security, and one or more related Market Makers are accepted into..., conducive to naturally having such markets. The Exchange believes that these factors, which directly benefit...-Regulatory Organizations; The NASDAQ Stock Market LLC; Notice of Filing of a Proposed Rule Change and...

  15. 77 FR 60129 - 60-Day Proposed Information Collection: Indian Health Service Forms To Implement the Privacy Rule...

    Science.gov (United States)

    2012-10-02

    .... Yvette Roubideaux, Director, Indian Health Service. [FR Doc. 2012-24119 Filed 10-1-12; 8:45 am] BILLING... DEPARTMENT OF HEALTH AND HUMAN SERVICES Indian Health Service 60-Day Proposed Information Collection: Indian Health Service Forms To Implement the Privacy Rule; Request for Public Comment AGENCY...

  16. 76 FR 34281 - Self-Regulatory Organizations; The NASDAQ Stock Market LLC; Notice of Filing of Proposed Rule...

    Science.gov (United States)

    2011-06-13

    ...-Regulatory Organizations; The NASDAQ Stock Market LLC; Notice of Filing of Proposed Rule Change To Adopt a Risk Monitor Mechanism June 7, 2011. Pursuant to Section 19(b)(1) of the Securities Exchange Act of... interested persons. \\1\\ 15 U.S.C. 78s(b)(1). \\2\\ 17 CFR 240.19b-4. I. Self-Regulatory Organization's...

  17. 76 FR 59462 - Self-Regulatory Organizations; BATS Y-Exchange, Inc.; Notice of Filing of Proposed Rule Change To...

    Science.gov (United States)

    2011-09-26

    ...-Regulatory Organizations; BATS Y-Exchange, Inc.; Notice of Filing of Proposed Rule Change To Amend and Restate the Amended and Restated Bylaws of BATS Global Markets, Inc. September 19, 2011. Pursuant to...\\ notice is hereby given that on September 7, 2011, BATS Y-Exchange, Inc. (the ``Exchange'' or ``BYX...

  18. 76 FR 67783 - Self-Regulatory Organizations; BATS Exchange, Inc.; Order Approving Proposed Rule Change To Amend...

    Science.gov (United States)

    2011-11-02

    ... SECURITIES AND EXCHANGE COMMISSION [Release No. 34-65646, File No. SR-BATS-2011-033] Self-Regulatory Organizations; BATS Exchange, Inc.; Order Approving Proposed Rule Change To Amend and Restate the Second Amended and Restated Certificate of Incorporation of BATS Global Markets, Inc. October 27, 2011. I...

  19. 77 FR 39535 - Self-Regulatory Organizations; NYSE Arca, Inc.; Notice of Filing of Proposed Rule Change To List...

    Science.gov (United States)

    2012-07-03

    ... would be listed in only five issues, specifically SPDR S&P 500 (SPY), Apple, Inc. (AAPL), SPDR Gold... S&P 500 (SPY), Apple, Inc. (AAPL), SPDR Gold Trust (GLD), Google Inc. (GOOG), and Amazon.com Inc...-Regulatory Organizations; NYSE Arca, Inc.; Notice of Filing of Proposed Rule Change To List and Trade Option...

  20. 75 FR 16706 - Proposed Significant New Use Rule for 1-Propene, 2,3,3,3-tetrafluoro-

    Science.gov (United States)

    2010-04-02

    ... Organisation for Economic Co-operation and Development (OECD) 403 test guideline) with rabbits would help... Objectives of the Proposed Rule A. Rationale During the review of the chemical substance P-07-601, EPA... premanufacture review because the Agency wants to achieve the following objectives with regard to the significant...

  1. 76 FR 71396 - Self-Regulatory Organizations; BATS Y-Exchange, Inc.; Order Approving Proposed Rule Change, as...

    Science.gov (United States)

    2011-11-17

    ... (the ``IPO''). The proposed rule change was published for comment in the Federal Register on September... Commission to register shares of Class A common stock and to disclose its intention to conduct an IPO offering those shares and to list those shares for trading on the Exchange. In connection with its IPO, the...

  2. 76 FR 58555 - Self-Regulatory Organizations; NYSE Amex LLC; Notice of Filing of Proposed Rule Change Relating...

    Science.gov (United States)

    2011-09-21

    ... and Exchange Commission (``Commission'') the proposed rule change as described in Items I, II, and III... encourage efficient usage of systems capacity by all ATP firms.\\3\\ The Exchange believes that it is in the best interests of all ATP firms and investors who access our markets to encourage efficient usage of...

  3. 77 FR 12626 - Self-Regulatory Organizations; New York Stock Exchange LLC; Notice of Filing of Proposed Rule...

    Science.gov (United States)

    2012-03-01

    ... member organization. The Exchange believes that the current definition, which includes certain foreign... organization falls outside of the definition of ``securities person.'' By changing the definition of approved...-Regulatory Organizations; New York Stock Exchange LLC; Notice of Filing of Proposed Rule Change Amending the...

  4. 76 FR 46860 - Self-Regulatory Organizations; New York Stock Exchange LLC; Notice of Filing of Proposed Rule...

    Science.gov (United States)

    2011-08-03

    ...-Regulatory Organizations; New York Stock Exchange LLC; Notice of Filing of Proposed Rule Change Amending the Definition of Approved Person To Exclude Foreign Affiliates, Creating a New Definition of ``Foreign... Items have been substantially prepared by the self-regulatory organization. The Commission is publishing...

  5. 77 FR 12637 - Self-Regulatory Organizations; NYSE Amex LLC; Notice of Filing of Proposed Rule Change Amending...

    Science.gov (United States)

    2012-03-01

    ... that is under common control with an NYSE Amex member organization falls outside of the definition of...-Regulatory Organizations; NYSE Amex LLC; Notice of Filing of Proposed Rule Change Amending the NYSE Amex Equities Definition of Approved Person To Exclude Foreign Affiliates, Eliminating the Application Process...

  6. 76 FR 46863 - Self-Regulatory Organizations; NYSE Amex LLC; Notice of Filing of Proposed Rule Change Amending...

    Science.gov (United States)

    2011-08-03

    ...-Regulatory Organizations; NYSE Amex LLC; Notice of Filing of Proposed Rule Change Amending the Definition of Approved Person To Exclude Foreign Affiliates, Creating a New Definition of ``Foreign Securities Affiliate... prepared by the self-regulatory organization. The Commission is publishing this notice to solicit comments...

  7. 75 FR 19436 - Self-Regulatory Organizations; The NASDAQ Stock Market LLC; Order Approving Proposed Rule Change...

    Science.gov (United States)

    2010-04-14

    ...-Regulatory Organizations; The NASDAQ Stock Market LLC; Order Approving Proposed Rule Change, as Modified by... NASDAQ Stock Market LLC (``Nasdaq'') filed with the Securities and Exchange Commission (``Commission... director's death, resignation or removal, or until his or her successor is duly elected and qualified. To...

  8. 75 FR 9985 - Self-Regulatory Organizations; The NASDAQ Stock Market LLC; Notice of Filing of Proposed Rule...

    Science.gov (United States)

    2010-03-04

    ...-Regulatory Organizations; The NASDAQ Stock Market LLC; Notice of Filing of Proposed Rule Change To Amend the... February 24, 2010, The NASDAQ Stock Market LLC (the ``Exchange'' or ``NASDAQ'') filed with the Securities... ``for'' such election is required to tender his or her resignation promptly following receipt of the...

  9. 76 FR 55343 - Pacific Halibut Fisheries; Extension of Public Comment Period on Proposed Rule for a Catch...

    Science.gov (United States)

    2011-09-07

    ... on Proposed Rule for a Catch Sharing Plan for Guided Sport and Commercial Fisheries in Alaska AGENCY... sport and commercial fisheries for Pacific halibut in waters of International Pacific Halibut Commission... comments identified by 0648-BA37 by any one of the following methods: Electronic submissions: Submit all...

  10. 76 FR 55984 - Self-Regulatory Organizations; ICE Clear Credit LLC; Notice of Filing of Proposed Rule Change To...

    Science.gov (United States)

    2011-09-09

    ... Participants with respect to SES Contracts), 26D-303 (SES Contract Adjustments), 26D-309 (Acceptance of SES... (``CDS'') contracts. Specifically, ICC is proposing to amend Chapter 26 of its rules to add Sections 26D... Sovereign Single Names'' or ``SES Contracts''). As discussed in more detail in Item II(A) below, Section 26D...

  11. 78 FR 40531 - Self-Regulatory Organizations; BATS Exchange, Inc.; Notice of Filing of a Proposed Rule Change...

    Science.gov (United States)

    2013-07-05

    ... technical corrections and amended the proposed rule text to clarify that any CLP Security listed on the Exchange shall be eligible for the CLP Program for the first six months that it is listed on the Exchange... Liquidity Providers to enhance liquidity on the Exchange in all Exchange-listed securities (the ``CLP...

  12. 77 FR 47472 - Self-Regulatory Organizations; The NASDAQ Stock Market LLC; Order Approving Proposed Rule Change...

    Science.gov (United States)

    2012-08-08

    ... From the Federal Register Online via the Government Publishing Office SECURITIES AND EXCHANGE COMMISSION Self-Regulatory Organizations; The NASDAQ Stock Market LLC; Order Approving Proposed Rule Change, as Modified by Amendment No. 1, To Adopt a New Market Maker Peg Order Available to Exchange Market...

  13. 76 FR 61416 - Self-Regulatory Organizations; The Nasdaq Stock Market LLC; Notice of Filing of Proposed Rule...

    Science.gov (United States)

    2011-10-04

    ... From the Federal Register Online via the Government Publishing Office SECURITIES AND EXCHANGE COMMISSION Self-Regulatory Organizations; The Nasdaq Stock Market LLC; Notice of Filing of Proposed Rule Change To Revise the Methodology for Determining When to Halt Trading Due to Extraordinary Market...

  14. 78 FR 15093 - Self-Regulatory Organizations; BOX Options Exchange LLC; Notice of Filing of Proposed Rule Change...

    Science.gov (United States)

    2013-03-08

    ...-Regulatory Organization's Statement of the Terms of Substance of the Proposed Rule Change The Exchange... order on a Leg and a Complex Order having the same time stamp. For the same reason, an Implied Order on... have priority over Legging Orders at the same price. ``Implied Order'' is defined as ``a Complex Order...

  15. 76 FR 24951 - Self-Regulatory Organizations; NASDAQ OMX PHLX LLC; Notice of Filing of Proposed Rule Change To...

    Science.gov (United States)

    2011-05-03

    ... experienced an explosive gain in popularity and have been the most actively traded options for the last two... unusual activity in both options and underlying stocks.\\16\\ \\16\\ These procedures have been effective for... the Commission, and all written communications relating to the proposed rule change between the...

  16. 75 FR 67424 - Self-Regulatory Organizations; Notice of Filing of Proposed Rule Change by NYSE Amex LLC Amending...

    Science.gov (United States)

    2010-11-02

    ... a Complex Order RFR Auction. NYSE Amex proposes a similar auction under Rule 980NY, with one... Holder representing the order that it be COA'd, the Exchange will send an RFR message to ATP Holders with an interface connection to NYSE Amex that have elected to receive such RFR messages. This RFR message...

  17. 78 FR 17251 - Self-Regulatory Organizations; The NASDAQ Stock Market LLC; Notice of Filing of Proposed Rule...

    Science.gov (United States)

    2013-03-20

    ...; proposed new language is in italics. * * * * * Chapter V Regulation of Trading on NOM * * * * * Sec. 3... quoted zero bid are usually deep out-of-the-money series that are perceived as having little if any... Commission's Internet Web site ( http://www.sec.gov/rules/sro.shtml ). Copies of the submission, all...

  18. 76 FR 61444 - Self-Regulatory Organizations; EDGX Exchange, Inc.; Notice of Filing of Proposed Rule Change To...

    Science.gov (United States)

    2011-10-04

    ... market participants to establish equilibrium between buying and selling interest and to ensure that... better cross-market measure of market volatility. Second, the Exchange proposes to change the... 11.13(c)(1) to re-number the cross- reference to Interpretation .05 of Rule 11.14 as Interpretation...

  19. 75 FR 4598 - Self-Regulatory Organizations; NYSE Amex, Inc.; Order Approving Proposed Rule Change To Establish...

    Science.gov (United States)

    2010-01-28

    ... Realtime Reference Prices Service January 22, 2010. I. Introduction On November 30, 2009, the NYSE Amex... thereunder,\\2\\ a proposed rule change to establish the NYSE Amex Realtime Reference Prices service and to... believes that the NYSE Amex Realtime Reference Prices service would provide a low-cost service that makes...

  20. 75 FR 500 - Self-Regulatory Organizations; New York Stock Exchange LLC; Order Approving a Proposed Rule...

    Science.gov (United States)

    2010-01-05

    .... 61043 (November 20, 2009), 74 FR 62612. On January 22, 2009, the Commission approved the formation of... wholly-owned subsidiary, NYSE Market, Inc., owns less than 9% of the aggregate limited partnership... proposed rule's impact on efficiency, competition, and capital formation. See 15 U.S.C. 78c(f). \\12\\ 15 U.S...

  1. 76 FR 54271 - Self-Regulatory Organizations; NASDAQ OMX PHLX LLC; Order Approving Proposed Rule Change Relating...

    Science.gov (United States)

    2011-08-31

    ... gross revenues received by the Director's firm or partnership; (v) provides professional services to a... partnership; or (vi) has a consulting or employment relationship with or provides professional services to the... considered the proposed rule's impact on efficiency, competition, and capital formation. See 15 U.S.C. 78c(f...

  2. 78 FR 31993 - Self-Regulatory Organizations; NASDAQ OMX BX, Inc.; Order Approving Proposed Rule Change Relating...

    Science.gov (United States)

    2013-05-28

    ... proposed rule's impact on efficiency, competition, and capital formation. See 15 U.S.C. 78c(f). \\6\\ 15 U.S... Director's firm or partnership; (v) provides professional services to a director, officer, or employee of a... more of the gross revenues received by the Director's firm or partnership; or (vi) has a consulting or...

  3. 77 FR 24236 - Self-Regulatory Organizations; NYSE Amex LLC; Notice of Filing of Proposed Rule Change Amending...

    Science.gov (United States)

    2012-04-23

    ... mnemonics. In addition, the business unit of the member organization acting as an SLP must enter proprietary..., pursuant to proposed Rule 107B(d)(3), the SLMM would be required to maintain unique mnemonics specifically dedicated to SLMM activity. Use of these unique mnemonics will enable SLMMs to meet their requirement under...

  4. 75 FR 82420 - Self-Regulatory Organizations, The NASDAQ Stock Market LLC; Order Approving Proposed Rule Change...

    Science.gov (United States)

    2010-12-30

    ... exchange is an activity of critical importance to financial markets and the investing public. Listing... concern since the SPAC must complete business combinations with a target having a fair market value of at...-Regulatory Organizations, The NASDAQ Stock Market LLC; Order Approving Proposed Rule Change To Amend IM-5101...

  5. 77 FR 17536 - Self-Regulatory Organizations; ICE Clear Credit LLC; Notice of Filing of Proposed Rule Change to...

    Science.gov (United States)

    2012-03-26

    ... Organizations; ICE Clear Credit LLC; Notice of Filing of Proposed Rule Change to Its Risk Model To Reduce the Current Level of Risk Mutualization Among Its Clearing Participants and To Modify the Initial Margin Risk Model so That It Is Easier for Market Participants To Measure Their Risk March 20, 2012. Pursuant to...

  6. 76 FR 1477 - Self-Regulatory Organizations; NYSE Arca, Inc.; Notice of Filing of Proposed Rule Change Relating...

    Science.gov (United States)

    2011-01-10

    ... 30-Year U.S. Treasury Bond Futures (``Treasury Index Futures Contract''). The Equity Index Futures... Bonds. The Equity Index Futures Contract provides an exposure to the S&P 500[supreg] Index. The Equity... Exchange proposes to list and trade shares of the following pursuant to NYSE Arca Equities Rule 8.200...

  7. 78 FR 12702 - Endangered and Threatened Species; Proposed Rule To List 66 Reef-Building Coral Species; Proposed...

    Science.gov (United States)

    2013-02-25

    ...; Proposed Reclassification of Elkhorn Acropora palmata and Staghorn Acropora cervicornis Under the... reclassifications of elkhorn (Acropora palmata) and staghorn (Acropora cervicornis) corals under the ESA until April...

  8. 77 FR 47662 - Proposed Supplementary Rules for Public Lands Within the Lower Lake Creek Special Recreation...

    Science.gov (United States)

    2012-08-09

    ... supplementary rules do not ban consumption, possession, or furnishing of alcohol by anyone who is of legal... Area. This area's regional popularity has led to undesirable impacts associated with large numbers of...

  9. New Fiscal Rules for the Czech Republic: Analysis of the Proposal

    Czech Academy of Sciences Publication Activity Database

    Baxa, Jaromír; Paulus, M.

    2016-01-01

    Roč. 2016, č. 1 (2016) Institutional support: RVO:67985556 Keywords : fiscal rules * fiscal policy * real-time data Subject RIV: AH - Economics http://library.utia.cas.cz/separaty/2016/E/baxa-0465222.pdf

  10. Society for immunotherapy of cancer (SITC) statement on the proposed changes to the common rule.

    Science.gov (United States)

    Kaufman, Howard L; Butterfield, Lisa H; Coulie, Pierre G; Demaria, Sandra; Ferris, Robert L; Galon, Jérôme; Khleif, Samir N; Mellman, Ira; Ohashi, Pamela S; Overwijk, Willem W; Topalian, Suzanne L; Marincola, Francesco M

    2016-01-01

    The Common Rule is a set of ethical principles that provide guidance on the management of human subjects taking part in biomedical and behavioral research in the United States. The elements of the Common Rule were initially developed in 1981 following a revision of the Declaration of Helsinki in 1975. Most academic facilities follow the Common Rule in the regulation of clinical trials research. Recently, the government has suggested a revision of the Common Rule to include more contemporary and streamlined oversight of clinical research. In this commentary, the leadership of the Society for Immunotherapy of Cancer (SITC) provides their opinion on this plan. While the Society recognizes the considerable contribution of clinical research in supporting progress in tumor immunotherapy and supports the need for revisions to the Common Rule, there is also some concern over certain elements which may restrict access to biospecimens and clinical data at a time when high throughput technologies, computational biology and assay standardization is allowing major advances in understanding cancer biology and providing potential predictive biomarkers of immunotherapy response. The Society values its professional commitment to patients for improving clinical outcomes with tumor immunotherapy and supports continued discussion with all stakeholders before implementing changes to the Common Rule in order to ensure maximal patient protections while promoting continued clinical research at this historic time in cancer research.

  11. Proposing New Heuristic Approaches for Preventive Maintenance Scheduling

    Directory of Open Access Journals (Sweden)

    majid Esmailian

    2013-08-01

    Full Text Available The purpose of preventive maintenance management is to perform a series of tasks that prevent or minimize production breakdowns and improve reliability of production facilities. An important objective of preventive maintenance management is to minimize downtime of production facilities. In order to accomplish this objective, personnel should efficiently allocate resources and determine an effective maintenance schedule. Gopalakrishnan (1997 developed a mathematical model and four heuristic approaches to solve the preventive maintenance scheduling problem of assigning skilled personnel to work with tasks that require a set of corresponding skills. However, there are several limitations in the prior work in this area of research. The craft combination problem has not been solved because the craft combination is assumed as given. The craft combination problem concerns the computation of all combinations of assigning multi skilled workers to accomplishment of a particular task. In fact, determining craft combinations is difficult because of the exponential number of craft combinations that are possible. This research provides a heuristic approach for determining the craft combination and four new heuristic approach solution for the preventive maintenance scheduling problem with multi skilled workforce constraints. In order to examine the new heuristic approach and to compare the new heuristic approach with heuristic approach of Gopalakrishnan (1997, 81 standard problems have been generated based on the criterion suggested by from Gopalakrishnan (1997. The average solution quality (SQ of the new heuristic approaches is 1.86% and in old heuristic approaches is 8.32%. The solution time of new heuristic approaches are shorter than old heuristic approaches. The solution time of new heuristic approaches is 0.78 second and old heuristic approaches is 6.43 second, but the solution time of mathematical model provided by Gopalakrishnan (1997 is 152 second.

  12. 77 FR 75085 - Proposed Significant New Use Rule on Ethoxylated, Propoxylated Diamine Diaryl Substituted...

    Science.gov (United States)

    2012-12-19

    ... (EcoSAR) analysis of test data on analogous amphoteric dyes, EPA predicts toxicity to aquatic organisms....gov/opptintr/newchems . IX. Economic Analysis EPA has evaluated the potential costs of establishing... during the development of the direct final rule. EPA's complete economic analysis is available in the...

  13. 75 FR 16217 - Self-Regulatory Organizations; Notice of Filing and Immediate Effectiveness of Proposed Rule...

    Science.gov (United States)

    2010-03-31

    ... Rule 5.2(j)(3)(A). The Fund is an ``index fund'' that seeks to provide daily investment results that... Investable Market Index (``Index''). The Fund does not seek to achieve its stated objective over a period of... because the Index for the Fund does not meet all of the ``generic'' listing requirements of Commentary .01...

  14. 78 FR 64413 - Proposed Waste Confidence Rule and Draft Generic Environmental Impact Statement

    Science.gov (United States)

    2013-10-29

    ... Confidence Rule and Draft Generic Environmental Impact Statement AGENCY: Nuclear Regulatory Commission... rescheduled the Waste Confidence public meetings it initially planned to hold in San Luis Obispo and Carlsbad... appropriations. The Waste Confidence public meeting in Carlsbad will now be held on November 18, 2013. The Waste...

  15. 76 FR 42152 - Self-Regulatory Organizations; Notice of Filing and Immediate Effectiveness of Proposed Rule...

    Science.gov (United States)

    2011-07-18

    .... Rule 7034(d): installation fees for cooling fans, perforated floor tiles and fiber downspouts, which are necessary items to support a higher density cabinet and fiber cross connects, relating to an order...-mail to [email protected] . Please include File Number SR-NASDAQ-2011-094 on the subject line...

  16. 75 FR 60352 - Notice of Proposed Rulemaking: Mortgage Acts and Practices - Advertising Rule

    Science.gov (United States)

    2010-09-30

    ... communications such as e- mail or text messages. Many types of entities market and advertise mortgage products... Acts and Practices - Advertising Rule AGENCY: Federal Trade Commission (FTC or Commission). ACTION...) relating to unfair or deceptive acts and practices that may occur with regard to mortgage advertising, the...

  17. 76 FR 9067 - Self-Regulatory Organizations; Notice of Filing and Immediate Effectiveness of Proposed Rule...

    Science.gov (United States)

    2011-02-16

    ... Exchange Rule 1014(b) as a regular member or a foreign currency options participant of the Exchange located... Securities Exchange, LLC's (``ISE'') Schedule of Fees, specifically ISE's Select Symbols and the rates... SECURITIES AND EXCHANGE COMMISSION [Release No. 34-63880; File No. SR-Phlx-2011-12] Self...

  18. 76 FR 28106 - Self-Regulatory Organizations; Notice of Filing and Immediate Effectiveness of Proposed Rule...

    Science.gov (United States)

    2011-05-13

    ... neither a SQT or a RSQT. A ROT is defined in Exchange Rule 1014(b) as a regular member or a foreign...- Dealers are assessed a higher rate as compared to other market participants and the Exchange is not seeking to increase that rate further.\\12\\ \\12\\ International Securities Exchange, LLC (``ISE'') assess...

  19. 75 FR 67791 - Self-Regulatory Organizations; Notice of Filing and Immediate Effectiveness of Proposed Rule...

    Science.gov (United States)

    2010-11-03

    ...\\ 17 CFR 240.19b-4. I. Self-Regulatory Organization's Statement of the Terms of Substance of the... month. (b) Financial Information Exchange (FIX) [Options] Ports Price FIX Trading Port $500/port/month... $475 per user per month (including data entitlement package). Nasdaq Workstation Post Trade See Rule...

  20. 75 FR 68392 - Self-Regulatory Organizations; The Options Clearing Corporation; Order Approving Proposed Rule...

    Science.gov (United States)

    2010-11-05

    ... Expand the Forms of Collateral Eligible for Incorporation in the System for Theoretical Analysis and Numerical Simulations Risk Management Methodology November 1, 2010. I. Introduction On August 25, 2010, The... Rules to expand the forms of collateral eligible for incorporation in OCC's System for Theoretical...

  1. 76 FR 20063 - Self-Regulatory Organizations; The Options Clearing Corporation; Order Approving a Proposed Rule...

    Science.gov (United States)

    2011-04-11

    ... treatment under Rule 15c3-1 \\2\\ of collateral and margin posted by clearing members participating in stock... collateral to the borrowing clearing member upon close-out of the stock loan transaction.\\5\\ One advantage of... the clearing member's options account at OCC and, to the extent that they offset the risk of options...

  2. 76 FR 60566 - Self-Regulatory Organizations; NASDAQ OMX PHLX LLC; Order Approving Proposed Rule Change...

    Science.gov (United States)

    2011-09-29

    ... Streaming Quote Traders and Remote Streaming Quote Traders Entering Certain Option Day Limit Orders... Streaming Quote Traders (``SQTs'') and Remote Streaming Quote Traders (``RSQTs'') to enter day limit orders... Rule 1080 to allow entry of day limit orders for the proprietary accounts of SQTs and RSQTs. Current...

  3. 75 FR 1426 - National Futures Association; Notice of Filing and Immediate Effectiveness of Proposed Rule...

    Science.gov (United States)

    2010-01-11

    ...) require that certain audio and video advertisements that appear on the Internet--like similar radio and... CPO/CTA Advisory Committees considered the growing use of social networking groups such as blogs, chat... advertisements, while participating in a chat room is a public appearance subject to FINRA rules. The guidance...

  4. 78 FR 13132 - Self-Regulatory Organizations; NASDAQ OMX PHLX LLC; Notice of Filing of Proposed Rule Change To...

    Science.gov (United States)

    2013-02-26

    ... is $1.00 greater than the selling price of 10 XYZ Jun 60 calls.\\7\\ Conversely, a net credit price of $1.00 would indicate that the purchase price of 10 XYZ Mar 50 calls is $1.00 less than the selling... orders (or crosses).\\15\\ This is described in proposed Rule 1063(e)(iv) and Advice C-2 (and cross...

  5. Coverage of Certain Preventive Services Under the Affordable Care Act. Final rules.

    Science.gov (United States)

    2015-07-14

    This document contains final regulations regarding coverage of certain preventive services under section 2713 of the Public Health Service Act (PHS Act), added by the Patient Protection and Affordable Care Act, as amended, and incorporated into the Employee Retirement Income Security Act of 1974 and the Internal Revenue Code. Section 2713 of the PHS Act requires coverage without cost sharing of certain preventive health services by non-grandfathered group health plans and health insurance coverage. These regulations finalize provisions from three rulemaking actions: Interim final regulations issued in July 2010 related to coverage of preventive services, interim final regulations issued in August 2014 related to the process an eligible organization uses to provide notice of its religious objection to the coverage of contraceptive services, and proposed regulations issued in August 2014 related to the definition of "eligible organization,'' which would expand the set of entities that may avail themselves of an accommodation with respect to the coverage of contraceptive services.

  6. 76 FR 64368 - Notice of Submission of Proposed Information Collection to OMB Homelessness Prevention Study

    Science.gov (United States)

    2011-10-18

    ... Proposed Information Collection to OMB Homelessness Prevention Study AGENCY: Office of Policy Development... Homelessness Prevention Study. The proposed information collection was approved under emergency review (OMB...) has submitted to OMB a request to extend approval for information collection for the Homelessness...

  7. 76 FR 81959 - Notice of Proposed Information Collection: Comment Request; Homelessness Prevention Study Site...

    Science.gov (United States)

    2011-12-29

    ... Information Collection: Comment Request; Homelessness Prevention Study Site Visits AGENCY: Office of the Chief.... This Notice also lists the following information: Title of Proposal: Homelessness Prevention Study Site... of the Paperwork Reduction Act requirements associated with HUD's Homelessness Prevention Study Site...

  8. 78 FR 68488 - Self-Regulatory Organizations; NYSE MKT LLC; Notice of Filing of Proposed Rule Change Amending...

    Science.gov (United States)

    2013-11-14

    ... bad faith or unethically.''). Rule 2010--Equities is a broad ethical concept that covers all unethical... regulatory responsibilities for certain NYSE rules and rule interpretations (``FINRA Incorporated NYSE Rules...

  9. Ruling out food allergy in pediatrics and preventing the "march" of the allergic child.

    Science.gov (United States)

    Fiocchi, Alessandro; Bouygue, Gabriel R; Terracciano, Luigi; Sarratud, Teresita; Martelli, Alberto

    2006-01-01

    When a child presents with an allergic symptom, the general pediatrician needs to discriminate which patient has to be sent to the specialist for an allergologic evaluation. If referred, the child will undergo not only skin-prick test, but also more complex specialistic evaluations that we define here as "the march of allergic children." The objective of this article is to overview the clinical evidence about possible diagnostic interventions to avoid unuseful referrals of children reported with allergy from the general to the specialist level. Data sources include PubMed, using a search algorithm selecting for diagnostic studies of respiratory and food allergy in all children to August 2005. Also included are commentaries based on the authors' clinical experience in the allergy unit of a University Hospital in Italy. No study prospectively assessed the rule-out efficacy of clinical history, physical evaluation, and skin-prick test panels on the allergic disease. Three prospective studies on in vitro panels of specific IgE sensitization matched entry criteria. Diverse trial designs and diagnostic criteria precluded meta-analytic methods. The use of in vitro panels proved effective in ruling out the allergic condition in children. The screening efficacy of panels of food and respiratory skin-prick tests remains to be evaluated. With sensitivities and negative predictive values exceeding 90%, in vitro panels can inform the decisions of pediatricians in their capacity as gateway to specialist care. Avoiding the march of allergic children from the GPs to the secondary level is a more realistic goal than preventing the allergic march.

  10. 76 FR 54514 - Self-Regulatory Organizations; Notice of Filing and Immediate Effectiveness of Proposed Rule...

    Science.gov (United States)

    2011-09-01

    ...- based virtual private networks. Currently, the Feed reflects the Exchange's view of the BBO data, at any...,\\10\\ in particular in that it is designed to prevent fraudulent and manipulative acts and practices...

  11. 78 FR 68782 - Public Meeting on the Improve Tracking of Workplace Injuries and Illnesses Proposed Rule

    Science.gov (United States)

    2013-11-15

    ... notice and comments requirements in the Administrative Procedure Act (APA) (5 U.S.C. 553) rather than... health standards. Section 553 of the APA, which governs this proposal, does not require a public hearing... presentation'' (5 U.S.C. 553(c)) (emphasis added). To promulgate a proposed regulation, the APA requires the...

  12. 75 FR 25887 - Self-Regulatory Organizations; Notice of Filing and Immediate Effectiveness of Proposed Rule...

    Science.gov (United States)

    2010-05-10

    ... Generally Accepted Accounting Principles (GAAP). The Exchange also proposes to require firms that fail to... and equitable principles of trade, to foster cooperation and coordination with persons engaged in...

  13. 75 FR 39301 - Self-Regulatory Organizations; Notice of Filing and Immediate Effectiveness of Proposed Rule...

    Science.gov (United States)

    2010-07-08

    ... error in the Fee Schedule. Specifically, the spelling of the word facilitation is being corrected. While... Payment. The Exchange also proposes correcting a typographical error. While changes to the Exchange's Fee...

  14. 76 FR 10530 - Supplemental Proposed Rule of Source Specific Federal Implementation Plan for Implementing Best...

    Science.gov (United States)

    2011-02-25

    ... person may provide written or oral comments, in English or Din[eacute], and data pertaining to our proposal at the Public Hearing. English-Din[eacute] translation services will be provided at both the Open...

  15. 78 FR 23184 - Proposed Significant New Use Rules on Certain Chemical Substances

    Science.gov (United States)

    2013-04-18

    ... correspondence, but do not submit any completed forms to this address. C. Regulatory Flexibility Act (RFA) On...) Protection in the workplace. Requirements as specified in Sec. 721.63(a)(1), (a)(3), (a)(4), (a)(6), (b...., workplace policies and procedures) shall be considered and implemented to prevent exposure, where feasible...

  16. Comparison of existing syncope rules and newly proposed anatolian syncope rule to predict short-term serious outcomes after syncope in the Turkish population.

    Science.gov (United States)

    Kayayurt, Kamil; Akoglu, Haldun; Limon, Onder; Ergene, Asım Oktay; Yavasi, Ozcan; Bayata, Serdar; Berk, Nergiz Vanden; Unluer, Erden Erol

    2012-04-20

    We wished to compare the San Francisco Syncope Rule (SFSR), Evaluation of Guidelines in Syncope Study (EGSYS) and the Osservatorio Epidemiologico sulla Sincope nel Lazio (OESIL) risk scores and to assess their efficacy in recognising patients with syncope at high risk for short-term adverse events (death, the need for major therapeutic procedures, and early readmission to the hospital). We also wanted to test those variables to designate a local risk score, the Anatolian Syncope Rule (ASR). This prospective, cohort study was conducted at the emergency department of a tertiary care centre. Between December 1 2009 and December 31 2010, we prospectively collected data on patients of ages 18 and over who presented to the emergency department with syncope. We enrolled 231 patients to the study. A univariate analysis found 23 variables that predicted syncope with adverse events. Dyspnoea, orthostatic hypotension, precipitating cause of syncope, age over 58 years, congestive heart failure, and electrocardiogram abnormality (termed DO-PACE) were found to predict short-term serious outcomes by logistic regression analysis and these were used to compose the ASR. The sensitivity of ASR, OESIL, EGSYS and SFSR for mortality were 100% (0.66 to 1.00); 90% (0.54 to 0.99), 80% (0.44 to 0.97) and 100% (0.66 to 1.00), respectively. The specificity of ASR, OESIL, EGSYS and SFSR for mortality were 78% (0.72 to 0.83); 76% (0.70 to 0.82); 80% (0.74 to 0.85) and 70% (0.63 to 0.76). The sensitivity of ASR, OESIL, EGSYS and SFSR for any adverse event were 97% (0.85 to 1.00); 70% (0.52 to 0.82); 56% (0.40 to 0.72) and 87% (0.72 to 0.95). The specificity of ASR, OESIL, EGSYS and SFSR for any adverse event were 72% (0.64 to 0.78); 82% (0.76 to 0.87); 84% (0.78 to 0.89); 78% (0.71 to 0.83), respectively. The newly proposed ASR appears to be highly sensitive for identifying patients at risk for short-term serious outcomes, with scores at least as good as those provided by existing diagnostic

  17. 76 FR 51453 - Self-Regulatory Organizations; The NASDAQ Stock Market LLC; Notice of Filing of Proposed Rule...

    Science.gov (United States)

    2011-08-18

    ... persistently produces robust reference prices, NOM is proposing to create a level of protection that prevents the market from moving beyond set thresholds. The thresholds consist of a reference price plus (minus... Trade Range threshold becomes the reference price for the next Acceptable Trade Range calculation. If an...

  18. The Outcomes of an Alcohol Prevention Program on Parents' Rule Setting and Self-efficacy: a Bidirectional Model.

    Science.gov (United States)

    Glatz, Terese; Koning, Ina M

    2016-04-01

    Most adolescents have their first encounter with alcohol in early or middle adolescence. Parents' rule setting about alcohol has been shown to be important to delay the onset and reduce the frequency of adolescents' alcohol drinking, but less is known about the potential role of parents' beliefs about their competence in and ability to influence their adolescents' drinking habits (i.e., parental self-efficacy [PSE], Bandura (Psychological Review, 84, 191-215, 1977). In this study, we examined the direction of influence between parents' rule setting and PSE as outcomes of the program "Prevention of Alcohol use in Students" (PAS), a prevention program aiming to reduce underage drinking by targeting parents and adolescents both separately and in a combined intervention. We tested two mediation processes in which the program would (a) have a direct effect on PSE, which in turn would increase parents' rule setting or (b) have a direct effect on parents' rule setting, which in turn would increase PSE. To examine these processes, we used a sample of 2562 parent-adolescent dyads (age 12 at baseline), followed annually over 3 years. The results showed that the combined intervention increased PSE via an increase in parents' rule setting. No significant effect of the intervention on rules about alcohol via PSE was found. This is the first study to test the mediation processes involving PSE and parental rule setting in an experimental context where parenting practices are being actively changed. The results suggest that giving parents concrete advice on how to deal with alcohol drinking in their adolescents and at the same time helping adolescents to develop healthy attitudes about alcohol drinking have a positive influence on parents' self-efficacy.

  19. Net modelling of energy mix among European Countries: A proposal for ruling new scenarios

    International Nuclear Information System (INIS)

    Dassisti, M.; Carnimeo, L.

    2012-01-01

    European energy policy pursues the objective of a sustainable, competitive and secure supply of energy. In 2007, the European Commission adopted an energy policy for Europe, which was supported by several documents on different aspects of energy and included an action plan to meet the major energy challenges Europe has to face. A farsighted diversified yearly mix of energies was suggested to countries, aiming at increasing security of supply and efficiency, but a wide and contemporary view of energy interchanges between states was not available. In a previous work of the same authors, energy import/export interchanges between European States were used to develop a geographic overview at one-glance. In this paper, the enhanced Interchange Energy Network (IEN) is investigated from a modelling point of view, as a Small-World Net, by supposing that connections can exist between States with a probability depending also on economic/political relations between countries. -- Highlights: ► Different view of the imports and exports of electric energy flows between European for potential use in ruling exchanges. ► Panel data from 1996 to 2008 as part of a network of exchanges was considered from Eurostat official database. ► The European import/export energy flows modelled as a network with Small-World phenomena, interpreting the evolution over the years. ► Interesting behavioural features as outcome derived, as shown for the case example of the Germany.

  20. 75 FR 26299 - Self-Regulatory Organizations; Notice of Filing and Immediate Effectiveness of Proposed Rule...

    Science.gov (United States)

    2010-05-11

    ... Index Fund. 288 KBH KB Home. 289 CREE Cree Inc. 290 SIRI Sirius XM Radio Inc. 291 MMR McMoRan...) (order approving SR-NYSEArca-2009-44). \\5\\ Index products would be included in the expansion if the underlying index level was under 200. NYSE Arca proposes adding the following 75 options classes to the Penny...

  1. 77 FR 30032 - Self-Regulatory Organizations; Fixed Income Clearing Corporation; Order Approving Proposed Rule...

    Science.gov (United States)

    2012-05-21

    ... liquidation and distribution of the property and funds of a GSD Netting Member that is a registered broker... Cross-Margining Agreement for this purpose. Segregation and Liquidation Considerations The proposed Market Professional Cross-Margining Program addresses concerns regarding segregation and liquidation...

  2. 75 FR 7985 - Blueberry Promotion, Research, and Information Order; Withdrawal of a Proposed Rule

    Science.gov (United States)

    2010-02-23

    ...-09-0021; FV-09-704] Blueberry Promotion, Research, and Information Order; Withdrawal of a Proposed... amend the Blueberry Promotion, Research, and Information Order (Order) by increasing the assessment rate on producers and importers who produce or import more than 2,000 pounds of highbush blueberries...

  3. 75 FR 5546 - Proposed Significant New Use Rule for Multi-walled Carbon Nanotubes

    Science.gov (United States)

    2010-02-03

    ... Organisation for Economic Co-operation and Development (OECD) 474 test guideline) in vivo, in bone marrow, by.... Rationale During review of the chemical substance P-08-199, EPA determined that one or more of the criteria... proposing this SNUR for a chemical substance that has undergone premanufacture review because the Agency...

  4. 77 FR 6608 - Self-Regulatory Organizations; BATS Exchange, Inc.; Order Granting Approval of Proposed Rule...

    Science.gov (United States)

    2012-02-08

    ... Liquidity Provider Program (``CLP Program''). The securities eligible to be included in the CLP Program... consecutive calendar months during the first two years the security is subject to the CLP Program, or until the security has been subject to the CLP Program for two years. In addition, the Exchange proposes to...

  5. 77 FR 37634 - Proposed Significant New Use Rule on Certain Chemical Substances

    Science.gov (United States)

    2012-06-22

    ... aluminum, rare earth doped, which were the subject of premanufacture notices (PMNs) P-12-22, P-12-23, P-12... PMNs. The five chemical substances are identified generically as complex strontium aluminum, rare earth... proposed SNUR, EPA considered relevant information about the toxicity of the chemical substances, likely...

  6. 75 FR 16543 - Self-Regulatory Organizations; Notice of Filing and Immediate Effectiveness of Proposed Rule...

    Science.gov (United States)

    2010-04-01

    ... making this rate change the Exchange seeks to remain competitive with other markets that often charge a higher rate. In proposing this new rate, NYSE Amex also seeks to adopt industry practice which sets the electronic broker dealer rate at a level slightly higher than the manual broker dealer charge. The pricing...

  7. 77 FR 1107 - Self-Regulatory Organizations; Options Clearing Corporation; Notice of Filing of Proposed Rule...

    Science.gov (United States)

    2012-01-09

    ... price of the OTC option, times the multiplier that determines the size of the OTC option. In the case of OTC index options on the S&P 500, the multiplier will be fixed at 1. The multipliers for additional... for whom clearing members may effect transactions in OTC options. Otherwise, the currently proposed...

  8. 77 FR 75243 - Self-Regulatory Organizations; Options Clearing Corporation; Order Approving Proposed Rule Change...

    Science.gov (United States)

    2012-12-19

    ... buyer should reduce bilateral credit risk, replacing it with the credit risk of the more robustly risk... otherwise be exposed to each other's credit risk could cause transactions that currently occur in the listed... OTC S&P 500 Index Options until a subsequent proposal concerning certain enhancements to OCC's risk...

  9. 75 FR 44037 - Self-Regulatory Organizations; Notice of Filing and Immediate Effectiveness of Proposed Rule...

    Science.gov (United States)

    2010-07-27

    ... proposes to pay a rebate to add liquidity through NOM in All Other Options of $0.20 per executed contract... Stock Market LLC Relating to Fees for Execution of Contracts on the NASDAQ Options Market July 21, 2010... Receipts/SPDRs (``SPY''),\\6\\ PowerShares QQQ Trust (``QQQQ'')[supreg] and Ishares Russell 2000 (``IWM...

  10. Proposed Title 20 rules could jeopardize delivery of family planning services.

    Science.gov (United States)

    1975-06-01

    It is the view of the Planned Parenthood Federation of America that the new Title 20 regulations of the Social Security Act could have an adverse effect on the progress that has been made in family planning services. Under the proposed regulations family planning services would exclude abortion. The regulations fail to specify that sexually active minors should be served on their own initiative and consent; that outreach, transportation, and child care should be cited as allowable family planning expenses; that a choice of method and of source of service should be provided; and that medical standards should be maintained. Planned Parenthood believes that the proposed regulations do not expand the availability of family planning services for low-income persons, which was the congressional intent.

  11. Hell no, we won't ACO. Providers, once eager to sign up for new program, say proposed rule on accountable care is a deal-breaker.

    Science.gov (United States)

    Evans, Melanie

    2011-06-06

    Hospital executives were eager to sign up for Medicare's proposed ACO program--until they saw the proposed rule spelling out how the CMS wants to structure it. They see too many risks, with too little chance of rewards. Stephen Mansfield, left, of Methodist Health System, describes the rule as "cold water" on the industry's interest and says he fears a promising opportunity will be sidelined. "I am so disappointed," Mansfield says.

  12. 77 FR 17533 - Self-Regulatory Organizations; ICE Clear Europe Limited; Order Approving Proposed Rule Change To...

    Science.gov (United States)

    2012-03-26

    ... into three categories: First, under ICE Clear Europe's current rule framework, CDS Contracts that arise... CDS Contract later. Accordingly, the first change establishes Rule 401(a)(xi) to permit ICE Clear... members of a contract under Rule 401(a)(xi), the contract will stand, unless it is voidable under Rule 404...

  13. Responding to the 2015 CMS Proposed Rule Changes for LTC Facilities: A Call to Redouble Efforts to Prepare Students and Practitioners for Nursing Homes.

    Science.gov (United States)

    Bern-Klug, Mercedes; Connolly, Robert; Downes, Deirdre; Galambos, Colleen; Kusmaul, Nancy; Kane, Rosalie; Hector, Paige; Beaulieu, Elise

    2016-01-01

    In July of 2015, the Federal Register published for public comment proposed rule changes for nursing homes certified to receive Medicare and/or Medicaid. If the final rules are similar to the proposed rules, they will represent the largest change in federal rules governing nursing homes since the Nursing Home Reform Act which was part of OBRA 1987. The proposed changes have the potential to enhance the quality of care and quality of life of nursing home residents. Many of the proposed changes would directly affect the practice of social work and would likely expand the role for nursing home social workers. This article discusses the role that members of the National Nursing Home Social Work Network (NNHSW Network) played in developing and submitting a response to CMS. The article provides the context for the publication of the proposed rules, describes the process used by the NNHSW Network to develop and build support for comments on these rules, and also includes the actual comments submitted to CMS. Social work education programs and continuing education programs throughout the country will continue to have an important role to play in helping to prepare social work students and practitioners for a career in long-term care.

  14. 76 FR 51447 - Self-Regulatory Organizations; Chicago Stock Exchange, Inc.; Notice of Filing of Proposed Rule...

    Science.gov (United States)

    2011-08-18

    ... broken by the exchange if they exceed the applicable percentage from the Reference Price, as noted in the table found under Rule 10(c)(1).\\9\\ The Reference Price, for purposes of Rule 10(c)(4), is the price...\\ Pursuant to Rule 10(c)(1), a security with a Reference Price of greater than zero and up to an including...

  15. 76 FR 51092 - Self-Regulatory Organizations; BATS Y-Exchange, Inc.; Notice of Filing of Proposed Rule Change To...

    Science.gov (United States)

    2011-08-17

    ... Trades will be broken by the Exchange if they exceed the applicable percentage from the Reference Price, as noted in the table found under Rule 11.17(c)(1).\\8\\ The Reference Price, for purposes of Rule 11... the Trading Pause Trigger Price.\\9\\ \\8\\ Pursuant to Rule 11.17(c)(1), a security with a Reference...

  16. 77 FR 6833 - Self-Regulatory Organizations; The NASDAQ Stock Market LLC; Notice of Filing of Proposed Rule...

    Science.gov (United States)

    2012-02-09

    ... provisions of the trust issued receipts rules, Bylaws, and all other rules and procedures of the Board of... NASDAQ Rule 5711(d) provides that a Commodity-Based Trust Share is a Trust Issued Receipt that holds a...-Linked Securities; Index-Linked Exchangeable Notes; Equity Gold Shares; Trust Certificates; Commodity...

  17. 75 FR 3774 - Self-Regulatory Organizations; The NASDAQ Stock Market LLC; Notice of Filing of Proposed Rule...

    Science.gov (United States)

    2010-01-22

    ... into any contract with or for a customer for the purchase or sale of such security, disclose to the... Control Relationship with Issuer Nasdaq Members shall comply with NASD Rule 2240 as if such Rule were part....] * * * * * 2262. Disclosure of Control Relationship with Issuer Nasdaq Members shall comply with FINRA Rule 2262...

  18. 78 FR 4955 - Self-Regulatory Organizations; NYSE Arca, Inc.; Order Granting Approval of Proposed Rule Change...

    Science.gov (United States)

    2013-01-23

    ... Equities Rule 5.2(j)(3) January 16, 2013. I. Introduction On September 27, 2012, NYSE Arca, Inc... personnel are subject to the provisions of Rule 204A-1 under the Advisers Act relating to codes of ethics. This Rule requires investment advisers to adopt a code of ethics that reflects the fiduciary nature of...

  19. 76 FR 38444 - [Self-Regulatory Organizations; NASDAQ OMX PHLX LLC; Order Granting Approval of Proposed Rule...

    Science.gov (United States)

    2011-06-30

    ... listing rules that govern the opening for trading of series and expiration months for approved options... to the rules in place for the listing of expiration months and series in stock or exchange-traded... that it has previously approved language in exchange listing rules that provide an exchange will open...

  20. 78 FR 68480 - Self-Regulatory Organizations; ICE Clear Credit LLC; Notice of Filing of Proposed Rule Change to...

    Science.gov (United States)

    2013-11-14

    ... Clearing of MCDX Index CDS Contracts and Make Conforming Changes to Existing Rules November 7, 2013... Chapter 26 of its rules to add Section 26H to provide for the clearance of the MCDX Untranched Contracts... Restructuring Rules) is modified to provide that it will not apply to MCDX Contracts (as such contracts are...

  1. 77 FR 7652 - Self-Regulatory Organizations; ICE Clear Europe Limited; Notice of Proposed Rule Change To Revise...

    Science.gov (United States)

    2012-02-13

    ... three categories: First, under the current Rules, CDS Contracts that arise following the end-of-day... ICE Clear Europe has notified the two affected clearing members of a contract under Rule 401(a)(xi), the contract will stand, unless it is voidable under Rule 404 (for example due to illegality or...

  2. 75 FR 13181 - Self-Regulatory Organizations; NYSE Arca, Inc.; Notice of Filing of Proposed Rule Change Relating...

    Science.gov (United States)

    2010-03-18

    ... wall'' provisions contained in Commentary .07 to NYSE Arca Equities Rule 8.600. PNC Global Investment... Investment Advisers Act Rule 204A-1. This Rule specifically requires the adoption of a code of ethics by an investment advisor to include, at a minimum: (i) Standards of business conduct that reflect the firm's...

  3. 76 FR 10899 - Proposed HHS Recommendation for Fluoride Concentration in Drinking Water for Prevention of Dental...

    Science.gov (United States)

    2011-02-28

    ... address changes in the prevalence of dental fluorosis, fluid intake among children, and the contribution... dental caries while limiting the risk of dental fluorosis. The proposed recommendation was published in... Drinking Water for Prevention of Dental Caries; Extension of Comment Period AGENCY: Office of the Secretary...

  4. Staff analysis of public comments on proposed rule 10 CFR Part 60, Disposal of High-Level Radioactive Wastes in Geologic Repositories

    International Nuclear Information System (INIS)

    1983-12-01

    On February 25, 1981, the Nuclear Regulatory Commission published rules which establish procedures for the licensing of geologic disposal, by the US Department of Energy, of high-level radioactive wastes. On July 8, 1981, proposed technical criteria which would be used in the evaluation of license applications under those procedural rules were published in the Federal Register. The Commission received 93 comment letters on the proposed technical criteria, 89 of which were received in time for the Commission to consider in preparing the final technical criteria which were published on June 21, 1983. This document presents a detailed analysis of the comments received on the proposed rule by the Commission's staff and also contains the Rationale for the Performance Objectives of 10 CFR Part 60

  5. 76 FR 51089 - Self-Regulatory Organizations; BATS Exchange, Inc.; Notice of Filing of Proposed Rule Change To...

    Science.gov (United States)

    2011-08-17

    ... Price, as noted in the table found under Rule 11.17(c)(1).\\8\\ The Reference Price, for purposes of Rule... Trading Pause Trigger Price.\\9\\ \\8\\ Pursuant to Rule 11.17(c)(1), a security with a Reference Price of... Reference Price of greater than $25.00 and up to and including $50.00 is subject to a 5% threshold; and a...

  6. Proposed Rule for Modification of Federal On Board Diagnostic Regulations for: Light Duty Vehicles, Light Duty Trucks, Medium Duty Passenger Vehicles, Complete Heavy Duty Vehicles and Engines Intended for Use in Heavy Duty Vehicles Weighing 14,000 Pounds

    Science.gov (United States)

    Following is information for the proposed rule for the Modification of Federal On Board Diagnostic Regulations for Light-Duty Vehicles, Light-Duty Trucks, etc. Includes links to Federal Register and final rule.

  7. [Reemergence of measles in vaccinated patients: report of 6 cases and proposals for prevention].

    Science.gov (United States)

    Agut-Busquet, Eugènia; Gené Tous, Emili; Navarro, Gemma; González, Araceli

    2016-06-01

    A 2014 measles outbreak in Catalonia affected 131 persons. We describe a series of 6 cases diagnosed in our emergency department. All the patients were under 31 years of age and complained of flu-like symptoms, including high fever and rash. Five had been properly vaccinated and one was a health care worker. A firm diagnosis of measles need not be made in the emergency department, but a high level of suspicion is important for ruling out complications, isolating the patient, and protecting health care staff at high risk for exposure. We found that 6% of the staff of our emergency department had a low level of immunity to measles. Given our findings, we suggest that preventive treatment is necessary when health care staff have been exposed to measles and their vaccination status is unknown.

  8. Fact Sheet: Clean Air Act Section 112(r): Accidental Release Prevention / Risk Management Plan Rule

    Science.gov (United States)

    EPA is required to publish regulations and guidance for chemical accident prevention at facilities that pose the greatest risk of harm from accidental releases of regulated flammable and toxic substances above threshold quantities.

  9. 75 FR 35865 - Self-Regulatory Organizations; Notice of Filing of Proposed Rule Change by NYSE Amex LLC Amending...

    Science.gov (United States)

    2010-06-23

    ... the rules of the New York Stock Exchange LLC (``NYSE''). See SR-NYSE-2010-43. Background Round lot... for a size within the standard unit (round- lot) of trading, which is 100 shares for most stocks, but... references to Odd-Lot Dealers in NYSE Amex Equities Rules 94 (``Designated Market Markers or Odd-Lot Dealers...

  10. 75 FR 25005 - Self-Regulatory Organizations; NYSE Arca, Inc.; Notice of Filing of Proposed Rule Change Amending...

    Science.gov (United States)

    2010-05-06

    ... ``Units'') that are traded on a national securities exchange and are defined as an ``NMS stock'' in Rule... securities and/or Financial Instruments and Money Marker Instruments); or (ii) interests in a trust or... the ETFS Platinum Trust ceases to be an ``NMS stock'' as provided for in Rule 5.4(b)(5) or the ETFS...

  11. 75 FR 1734 - Children’s Online Privacy Protection Rule Safe Harbor Proposed Self-Regulatory Guidelines; i-SAFE...

    Science.gov (United States)

    2010-01-13

    ... FEDERAL TRADE COMMISSION 16 CFR Part 312 Children's Online Privacy Protection Rule Safe Harbor... safe harbor provision of the Children's Online Privacy Protection Rule. FOR FURTHER INFORMATION CONTACT: Mamie Kresses, Attorney, (202) 326- 2070, Division of Advertising Practices, Federal Trade Commission...

  12. 76 FR 62873 - Self-Regulatory Organizations; NYSE Arca, Inc.; Order Granting Approval of Proposed Rule Change...

    Science.gov (United States)

    2011-10-11

    ... leverage, respectively. Stock Selection Algorithm The Sub-Adviser will use an algorithm to give a relative weight to the three decile rankings, combining them in a single ranking (combined ranking). The algorithm... provisions of Rule 204A-1 under the Advisers Act relating to codes of ethics. This Rule requires investment...

  13. 76 FR 51442 - Self-Regulatory Organizations; NYSE Arca, Inc.; Notice of Filing of Proposed Rule Change To List...

    Science.gov (United States)

    2011-08-18

    ... Rule 204A-1 under the Advisers Act relating to codes of ethics. This Rule requires investment advisers to adopt a code of ethics that reflects the fiduciary nature of the relationship to clients as well... Selection Algorithm The Sub-Adviser uses an algorithm to give a relative weight to the three decile rankings...

  14. 75 FR 80553 - Self-Regulatory Organizations; NYSE Amex LLC; Order Approving a Proposed Rule Change Relating to...

    Science.gov (United States)

    2010-12-22

    ... these provisions to Stock/Complex Orders; (iii) delete Rule 963.1NY; (iv) add Rule 980NY(e) to establish... executed at a net debit or credit with another ATP Holder without giving priority to equivalent bids... specialist).\\7\\ Upon receipt of a COA-eligible order, and direction from the entering ATP Holder that an...

  15. 77 FR 39288 - Self-Regulatory Organizations; NYSE MKT LLC; Notice of Filing of Proposed Rule Change Amending...

    Science.gov (United States)

    2012-07-02

    ... (i) ``ATP Holders,'' as that term is defined in Rule 900.2NY(5); (ii) Sponsored Participants, as that term is defined in Rule 900.2NY(77); and (iii) non-ATP Holder broker-dealers and vendors that request... change as described in Items I, II, and III below, which Items have been prepared by the self-regulatory...

  16. 76 FR 814 - Self-Regulatory Organizations; NASDAQ OMX PHLX LLC; Order Approving a Proposed Rule Change To...

    Science.gov (United States)

    2011-01-06

    ... responsibilities, and trade correction and exemptive relief data. Rule 515, as well as OFPA C-8, also discusses the... combined Rule 511 and to adopt for specialist units \\9\\ an objective review process that is similar to the... broker questionnaire. The Exchange believes that the questionnaire, which is subjective in nature and not...

  17. 76 FR 12180 - Self-Regulatory Organizations; Notice of Filing of Proposed Rule Change by NASDAQ OMX PHLX LLC...

    Science.gov (United States)

    2011-03-04

    ... Amendments to NASDAQ OMX PHLX LLC's Limited Liability Company Agreement, By-Laws, Rules, Advices and... Limited Liability Company Agreement and By-Laws; (2) eliminate the Series A Preferred Shareholder and... Exchange's Limited Liability Company Agreement (``LLC Agreement'') By-Laws, Rules, Advices and Regulations...

  18. 76 FR 4963 - Self-Regulatory Organizations; NYSE Arca, Inc.; Order Approving a Proposed Rule Change To List...

    Science.gov (United States)

    2011-01-27

    ... NYSE Arca Equities Rule 8.200 applies to Trust Issued Receipts that invest in ``Financial Instruments... continued listing requirements applicable to Trust Issued Receipts in NYSE Arca Equities Rule 8.200 and... Holders \\16\\ acting as registered Market Makers \\17\\ in Trust Issued Receipts to facilitate surveillance...

  19. 77 FR 12631 - Self-Regulatory Organizations; NYSE Arca, Inc.; Order Granting Approval of Proposed Rule Change...

    Science.gov (United States)

    2012-03-01

    ... Arca Equities Rule 8.200, Commentary .02, which permits the trading of Trust Issued Receipts either by... applies to Trust Issued Receipts that invest in ``Financial Instruments.'' The term ``Financial... Trust Issued Receipts in NYSE Arca Equities Rule 8.200 and Commentary .02 thereto. The Exchange further...

  20. 77 FR 29435 - Self-Regulatory Organizations; The NASDAQ Stock Market LLC; Notice of Filing of Proposed Rule...

    Science.gov (United States)

    2012-05-17

    ... protocols. \\8\\ Child Orders that require routing will be routed by NES, NASDAQ's wholly-owned routing broker... executed within the NASDAQ system under NASDAQ's existing processing rules, or made available for routing under NASDAQ's current routing rules.\\3\\ [[Page 29436

  1. 77 FR 32157 - Self-Regulatory Organizations; NYSE Amex LLC; Notice of Filing of Proposed Rule Change Defining a...

    Science.gov (United States)

    2012-05-31

    ... in each class compete in the Specialist Pool on a size pro-rata basis, and do not compete at all for... pro-rata basis. \\3\\ Under the rule, the Specialist's pro-rata allocation may receive additional... would move to the next step in the allocation process--size pro rata allocation pursuant to Rule 964NY(b...

  2. 77 FR 39763 - Self-Regulatory Organizations; NYSE Arca, Inc.; Order Granting Approval of Proposed Rule Change...

    Science.gov (United States)

    2012-07-05

    ... tracking stock. However, holders of the tracking stock may not have the same rights as holders of the... conditions or for reasons that, in the view of the Exchange, make trading in the Shares inadvisable. \\19\\ See... the provisions of Rule 204A-1 under the Advisers Act relating to codes of ethics. This Rule requires...

  3. 78 FR 24276 - Self-Regulatory Organizations; NYSE Arca, Inc.; Order Granting Approval of Proposed Rule Change...

    Science.gov (United States)

    2013-04-24

    ... interest rate adjustment formula and a right of demand on the part of the holder thereof to receive payment... reached or because of market conditions or for reasons that, in the view of the Exchange, make trading in... provisions of Rule 204A-1 under the Advisers Act relating to codes of ethics. This Rule requires investment...

  4. 78 FR 76867 - Self-Regulatory Organizations; NYSE Arca, Inc.; Notice of Filing of Proposed Rule Change Relating...

    Science.gov (United States)

    2013-12-19

    ... Exchange has prepared summaries, set forth in sections A, B, and C below, of the most significant parts of... Statement''). The description of the operation of the Trust and the Funds herein is based, in part, on the... Rule 8.200); Commodity-Based Trust Shares (as described in NYSE Arca Equities Rule 8.201); Currency...

  5. 76 FR 61425 - Self-Regulatory Organizations; EDGA Exchange, Inc.; Notice of Filing of Proposed Rule Change by...

    Science.gov (United States)

    2011-10-04

    ... and selling interest and to ensure that market participants have an opportunity to become aware of and... products, such as the E-Mini and SPDR S&P 500 Exchange-Traded Fund (``SPY''), will allow for a better cross... cross- reference to Interpretation .05 of Rule 11.14 as Interpretation .01 of Rule 11.14. 2. Statutory...

  6. 78 FR 15990 - Self-Regulatory Organizations; NYSE Arca, Inc.; Order Granting Approval of Proposed Rule Change...

    Science.gov (United States)

    2013-03-13

    ..., 2013. I. Introduction On January 4, 2013, NYSE Arca, Inc. (``Exchange'' or ``NYSE Arca'') filed with... personnel are subject to the provisions of Rule 204A-1 under the Advisers Act relating to codes of ethics. This Rule requires investment advisers to adopt a code of ethics that reflects the fiduciary nature of...

  7. 77 FR 47131 - Self-Regulatory Organizations; NYSE Arca, Inc.; Order Granting Approval of Proposed Rule Change...

    Science.gov (United States)

    2012-08-07

    .... I. Introduction On May 31, 2012, NYSE Arca, Inc. (``Exchange'' or ``NYSE Arca'') filed with the... personnel are subject to the provisions of Rule 204A-1 under the Advisers Act relating to codes of ethics. This Rule requires investment advisers to adopt a code of ethics that reflects the fiduciary nature of...

  8. 75 FR 36138 - Self-Regulatory Organizations; New York Stock Exchange LLC; Notice of Filing of Proposed Rule...

    Science.gov (United States)

    2010-06-24

    ... evolution of the market probe response that Floor brokers have always been entitled to receive and may... Comments Use the Commission's Internet comment form ( http://www.sec.gov/rules/sro.shtml ); or Send an e... post all comments on the Commission's Internet Web site ( http://www.sec.gov/rules/sro.shtml ). Copies...

  9. 75 FR 36140 - Self-Regulatory Organizations; NYSE Amex LLC; Notice of Filing of Proposed Rule Change Amending...

    Science.gov (United States)

    2010-06-24

    ... dissemination of this MOC/LOC imbalance information is the electronic evolution of the market probe response... Comments Use the Commission's Internet comment form ( http://www.sec.gov/rules/sro.shtml ); or Send an e... Commission will post all comments on the Commission's Internet Web site ( http://www.sec.gov/rules/sro.shtml...

  10. 77 FR 61804 - Self-Regulatory Organizations; NYSE Arca, Inc.; Order Granting Approval of Proposed Rule Change...

    Science.gov (United States)

    2012-10-11

    ... Series Under NYSE Arca Equities Rule 5.2(j)(3), Commentary .02 October 4, 2012. I. Introduction On August... the Funds pursuant to NYSE Arca Equities Rule 5.2(j)(3), Commentary .02, which governs the listing and... amount at maturity. The 2018 Index measures the performance of investment-grade U.S. municipal bonds...

  11. 78 FR 11245 - Self-Regulatory Organizations; NYSE Arca, Inc.; Order Granting Approval of Proposed Rule Change...

    Science.gov (United States)

    2013-02-15

    ... and potential rewards of investing in both equity funds and bond funds. Certain of the Preferred... First Trust Preferred Securities and Income ETF Under NYSE Arca Equities Rule 8.600 February 8, 2013. I...'') of the First Trust Preferred Securities and Income ETF (``Fund'') under NYSE Arca Equities Rule 8.600...

  12. 77 FR 7643 - Self-Regulatory Organizations; NYSE Arca, Inc.; Order Granting Approval of a Proposed Rule Change...

    Science.gov (United States)

    2012-02-13

    ... Bond ETF; and Russell Real Return ETF Under NYSE Arca Equities Rule 8.600 February 7, 2012. I... list and trade shares (``Shares'') of the Russell Global Opportunity ETF; Russell Bond ETF; and Russell Real Return ETF (each, a ``Fund'' and, collectively, ``Funds'') under NYSE Arca Equities Rule 8.600...

  13. 76 FR 9065 - Self-Regulatory Organizations; NYSE Arca, Inc.; Order Approving a Proposed Rule Change To List...

    Science.gov (United States)

    2011-02-16

    ... Municipal Bond ETF (``ETF'' or ``Fund'') under NYSE Arca Equities Rule 5.2(j)(3), Commentary .02. The... the SPDR Nuveen S&P High Yield Municipal Bond ETF February 9, 2011. I. Introduction On December 21... shares (``Shares'') under NYSE Arca Equities Rule 5.2(j)(3), Commentary .02, which governs the listing...

  14. 76 FR 76205 - Self-Regulatory Organizations; NYSE Arca, Inc.; Notice of Filing of Proposed Rule Change Relating...

    Science.gov (United States)

    2011-12-06

    ... Shares \\3\\ (``Shares'') under NYSE Arca Equities Rule 8.600: Russell Global Opportunity ETF; Russell Bond... and Trading of the Russell Global Opportunity ETF; Russell Bond ETF; and Russell Real Return ETF Under NYSE Arca Equities Rule 8.600 December 1, 2011. Pursuant to Section 19(b)(1) of the Securities Exchange...

  15. 77 FR 26798 - Self-Regulatory Organizations; NYSE Amex LLC; Notice of Filing of Proposed Rule Change to List...

    Science.gov (United States)

    2012-05-07

    ... Positions......... 4.64 Total Metals Positions..... 17.39 Livestock Cattle Live Short 3.87 Hogs Lean Short 2... September 30, 2011. These are not the actual signals or weights of the Fund. The Index construction rules... construction rules and other information about the Index can be found on Morningstar's Web site at http...

  16. Accident prevention on ski slopes - Perceptions of safety and knowledge of existing rules.

    Science.gov (United States)

    Hildebrandt, Carolin; Mildner, Esmeralda; Hotter, Barbara; Kirschner, Werner; Höbenreich, Chistoph; Raschner, Christian

    2011-07-01

    Increases in the numbers of people participating in snow sports raise safety concerns. Despite declining numbers of skiing injuries among recreational skiers, collisions resulting in severe injuries appear to be on the rise. Skiers' risk of injury depends on a considerable number of different factors but only a few studies have investigated risk-taking behaviour and knowledge of proper skiing behaviour. To promote safe skiing the International Ski Federation (FIS) introduced regulations in 1967. We investigated participants' familiarity with the FIS regulations on the ski slopes in relation to age, skiing ability and country of origin. Random interviews were conducted with 1450 recreational skiers at 17 ski resorts in Tyrol, an Austrian province. A questionnaire assessing skiers' knowledge of existing rules, their intuitive behaviour in given situations and perceptions of safety was developed. The study revealed that beginners, young skiers and those who were not local residents displayed insufficient knowledge. Risk-inducing situations that could result in collisions, such as moving upwards during carving, were largely assessed incorrectly. Appropriate intuitive behaviour increases with experience, and beginners are less able to implement FIS regulations than more experienced skiers. Ski resorts, the media and schools should direct educational efforts toward these high-risk groups. More research is needed to determine the causal connection between skiing injuries and disregard of the FIS Rules. Copyright © 2011 Elsevier Ltd. All rights reserved.

  17. The new proposal for harmonised rules for the online sales of tangible goods: conformity, lack of conformity and remedies: in-depth analysis

    NARCIS (Netherlands)

    Smits, Jan

    2016-01-01

    Upon request by the JURI Committee, this paper evaluates the European Commission proposal of 9 December 2015 harmonizing certain civil law contractual rules for Online Shopping. The directive's approach concerning conformity, lack of conformity and remedies is analized. It also examines the question

  18. 77 FR 36314 - Self-Regulatory Organizations; NYSE Arca, Inc.; Notice of Filing of Proposed Rule Change Relating...

    Science.gov (United States)

    2012-06-18

    ... relating to codes of ethics. This Rule requires investment advisers to adopt a code of ethics that reflects... States, the Commodity Credit Corporation, the Federal Financing Bank, the Student Loan Marketing...

  19. 75 FR 20016 - Self-Regulatory Organizations; Notice of Filing of Proposed Rule Change by NASDAQ OMX PHLX, Inc...

    Science.gov (United States)

    2010-04-16

    ... quote spread parameters appear in a chart in Advice F-6 and in the text of Rule 1014(c)(i)(A)(1)(a). The... that there exists a pattern or practice of violative conduct without exceptional circumstances or when...

  20. 77 FR 73104 - Self-Regulatory Organizations; The NASDAQ Stock Market LLC; Order Approving Proposed Rule Change...

    Science.gov (United States)

    2012-12-07

    ..., stock price, the number of publicly traded shares, and corporate governance standards to ensure... corporate governance listing standards, Nasdaq Rule 5101 also gives the Exchange discretion to deny listing...

  1. 77 FR 68191 - Self-Regulatory Organizations; NYSE MKT LLC; Notice of Filing of Proposed Rule Change Deleting...

    Science.gov (United States)

    2012-11-15

    ... executed them. Floor brokers in 1994, in other words, could stand at the point of sale and trade more... Rule 95(c), as these are markings that were required to be included on manual order tickets that were...

  2. 77 FR 62576 - Self-Regulatory Organizations; NYSE MKT LLC; Notice of Filing of Proposed Rule Change, as...

    Science.gov (United States)

    2012-10-15

    ... adviser; and (vi) Any business or personal relationship of the compensation consultant, legal counsel... factors should explicitly include consideration of the personal and business relationships between... rule; a discussion of the exchange's consideration of factors relevant to compensation committee...

  3. Getting ready for identity theft rules: creating a prevention program for your medical practice.

    Science.gov (United States)

    Cascardo, Debra

    2009-01-01

    Identity theft worries have found their way into medical practices. By August 1, 2009, all "creditors" must have a written program to prevent, detect, and minimize damage from identity theft. Any medical practice that bills patients is considered a creditor. Like HIPAA, these new Red Flag guidelines will serve to protect your practice from lawsuits as well as protect your patients from identity theft of their financial, personal, and medical information.

  4. [AIDS/education and prevention: methodologic proposal for the development of educational games].

    Science.gov (United States)

    Araújo, M F; de Almeida, M I; da Silva, R M

    2000-01-01

    The development of educational resources to mediate actions in health education and AIDS prevention has been a challenge to health's educators. Due to the undeniable importance of this kind of material in environments favourable to learning, the authors created a methodological proposal to be used in the elaboration of educative games with the purpose of mediating educational measures and the prevention of HIV/AIDS. For theoretical framework, the study relied on the ideas/premises about problem solving, adapted from Charles Manguerez's "arch method", which where put into practice in public schools and health institutions in the state of Ceara, having as study population a group of students (180), aged 13 to 19 years, from the period of 1995 to 1997. Data collection occurred during four workshops, according to a predefined scheme. The results dealing with the meaning of the game, place of action and social environment were obtained from the teenagers while they were engaged in the games and further analysed by them, resulting in the formulation of (03) educative games (memor AIDS, baralhAIDS and dominAIDS). The authors conclude that the proposal is favourable to participatory action, encouraging during its entire process the development of intellectual and creative skills, by way of mobilizing human capacities and exercising associations related to the AIDS epidemic. Due to its clarity, the authors consider the proposal scientifically acceptable as a methodological guideline for the elaboration of educative games.

  5. Triple surveillance: a proposal for an integrated strategy to support and accelerate birth defect prevention

    Science.gov (United States)

    Mastroiacovo, Pierpaolo

    2018-01-01

    Abstract Preventing neural tube defects (NTDs) easily qualifies as a high‐value opportunity to improve childhood survival and health: the unmet need is significant (major preventable burden), the intervention is transformative (providing sufficient folic acid), and delivery strategies (e.g., fortification) are effective in low‐resource countries. Yet, NTD prevention is lagging. Can public health surveillance help fix this problem? Critics contend that surveillance is largely unnecessary, that limited resources are best spent on interventions, and that surveillance is unrealistic in developing countries. The counterargument is twofold: (1) in the absence of surveillance, interventions will provide fewer benefits and cost more and (2) effective surveillance is likely possible nearly everywhere, with appropriate strategies. As a base strategy, we propose “triple surveillance:” integrating surveillance of cause (folate insufficiency), of disease occurrence (NTD prevalence), and of health outcomes (morbidity, mortality, and disability). For better sustainability and usefulness, it is crucial to refocus and streamline surveillance activities (no recreational data collection), weave surveillance into clinical care (integrate in clinical workflow), and, later, work on including additional risk factors and pediatric outcomes (increase benefits at low marginal cost). By doing so, surveillance becomes not a roadblock but a preferential path to prevention and better care. PMID:29532515

  6. Willingness of Mentally Ill Individuals to Sign Up for a Novel Proposal to Prevent Firearm Suicide.

    Science.gov (United States)

    Vars, Fredrick E; McCullumsmith, Cheryl B; Shelton, Richard C; Cropsey, Karen L

    2017-08-01

    The study goal was to determine whether a significant number of high suicide risk individuals would confidentially put their own names onto a list to prevent future gun purchases. An anonymous written survey was administered in an inpatient psychiatric unit and two outpatient psychiatric clinics at an academic medical center. Two hundred forty individuals were approached to fill out the survey, of whom 200 (83.3%) did so. Forty-six percent of participants stated that they would put their own name onto the list. This novel suicide prevention proposal, a Do-Not-Sell List, would appeal to many people at high risk for suicide. © 2016 The American Association of Suicidology.

  7. Proposal for an IT Security Standard for Preventing Tax Fraud in Cash Registers

    Science.gov (United States)

    Neuhaus, Mathias; Wolff, Jörg; Zisky, Norbert

    This paper describes a technology solution for preventing tax fraud in electronic cash registers (ECR) and point of sale (POS) systems. The solution is based on electronic signatures, and as a result, any alterations to protected data will be detected. The signed transaction data can be stored on various electronic memory devices. Technical provisions enable the estimation of transaction volumes, even after tampering or loss of data. In this way the solution presented here differs significantly from other fiscal solutions where a pattern of approvals for ECRs and permanent technical supervision of the market is necessary. This paper is focused on the architecture, the protocols and the usability of the proposed system.

  8. Proposal to modify Rule 10a and to delete Recommendation 10a(3) from the International Code of Nomenclature of Prokaryotes.

    Science.gov (United States)

    Oren, Aharon

    2017-09-01

    Principle 2 of the Prokaryotic Code, as modified by the ICSP in 1999, reads: 'The nomenclature of prokaryotes is not independent of botanical and zoological nomenclature. When naming new taxa in the rank of genus or higher, due consideration is to be given to avoiding names which are regulated by the International Code of Zoological Nomenclature and the International Code of Nomenclature for algae, fungi and plants'. But in the current version of the Prokaryotic Code no Rule implements this version of Principle 2. I therefore propose adding the following sentence to Rule 10a: 'As from January 2001, newly proposed generic names must not be later homonyms of names in use in botany or zoology'. Recommendation 10a(3) of the Code states: 'Avoid introducing into bacteriology as generic names such names as are in use in botany or zoology, in particular well-known names'. This Recommendation contravenes the current version of Principle 2 and the proposed new version of Rule 10a. Therefore I propose to delete Recommendation 10a(3) from the Prokaryotic Code.

  9. Coverage of certain preventive services under the Affordable Care Act. Interim final rules.

    Science.gov (United States)

    2014-08-27

    This document contains interim final regulations regarding coverage of certain preventive services under section 2713 of the Public Health Service Act (PHS Act), added by the Patient Protection and Affordable Care Act, as amended, and incorporated into the Employee Retirement Income Security Act of 1974 and the Internal Revenue Code. Section 2713 of the PHS Act requires coverage without cost sharing of certain preventive health services by non-grandfathered group health plans and health insurance coverage. Among these services are women's preventive health services, as specified in guidelines supported by the Health Resources and Services Administration (HRSA). As authorized by the current regulations, and consistent with the HRSA Guidelines, group health plans established or maintained by certain religious employers (and group health insurance coverage provided in connection with such plans) are exempt from the otherwise applicable requirement to cover certain contraceptive services. Additionally, under current regulations, accommodations are available with respect to the contraceptive coverage requirement for group health plans established or maintained by eligible organizations (and group health insurance coverage provided in connection with such plans), and student health insurance coverage arranged by eligible organizations that are institutions of higher education, that effectively exempt them from this requirement. The regulations establish a mechanism for separately furnishing payments for contraceptive services on behalf of participants and beneficiaries of the group health plans of eligible organizations that avail themselves of an accommodation, and enrollees and dependents of student health coverage arranged by eligible organizations that are institutions of higher education that avail themselves of an accommodation. These interim final regulations augment current regulations in light of the Supreme Court's interim order in connection with an

  10. 75 FR 41258 - Self-Regulatory Organizations; The NASDAQ Stock Market LLC; Notice of Filing of a Proposed Rule...

    Science.gov (United States)

    2010-07-15

    ... Halt Cross as set forth in subsection (b)(2)-(4) above. (4) No change. * * * * * II. Self-Regulatory... is set forth in Sections A, B, and C below. A. Self-Regulatory Organization's Statement of the... from volatility to companies that list with it [sic]. \\12\\ NYSE Rule 1000(a)(iv). \\13\\ NYSE's LRP...

  11. 76 FR 26085 - Endangered and Threatened Wildlife and Plants; Proposed Rule To Revise the List of Endangered and...

    Science.gov (United States)

    2011-05-05

    ... lacked gray wolf populations were the coastal and interior portions of California, the arid deserts and..., intermingling in post-glacial times along contact zones. The results of recent molecular genetic analyses (e.g... 1978 rule, we also identified Isle Royale National Park, Michigan, and Minnesota wolf management zones...

  12. 77 FR 50187 - Self-Regulatory Organizations; NASDAQ OMX PHLX LLC; Order Approving a Proposed Rule Change With...

    Science.gov (United States)

    2012-08-20

    ... routing destination, or a non-affiliate third-party Routing Broker that affects one or more orders.'' For... will be required to provide notice of the cancellation to all affected members as soon as practicable... nondiscriminatory fashion.\\14\\ \\14\\ See Phlx Rule 3315(d)(3). Phlx and NES will be required to assign all error...

  13. 76 FR 61453 - Self-Regulatory Organizations; C2 Options Exchange, Incorporated; Notice of Proposed Rule Change...

    Science.gov (United States)

    2011-10-04

    ... Authority, Inc. (``FINRA''), and staffs of the Commission and the Commodity Futures Trading Commission...\\ Upon reopening, a rotation shall be held in each class of options in accordance with Exchange Rule 6.11..., including but not limited to, no rotation, an abbreviated rotation or any other variation in the manner of...

  14. 76 FR 62118 - Self-Regulatory Organizations; NYSE Arca, Inc.; Order Approving a Proposed Rule Change Amending...

    Science.gov (United States)

    2011-10-06

    ... Rule 6.96(b)(2) To Make Permanent the Pilot Program That Permits the Exchange To Accept Inbound Orders Routed by Archipelago Securities LLC in Its Capacity as a Facility of Affiliated Exchanges and To Clarify... program that permits the Exchange to accept inbound orders routed by Archipelago Securities LLC (``Arca...

  15. 76 FR 53515 - Self-Regulatory Organizations; NYSE Arca, Inc.; Notice of Filing of Proposed Rule Change Amending...

    Science.gov (United States)

    2011-08-26

    ... Options Rule 6.96(b)(2) To Make Permanent the Pilot Program That Permits the Exchange To Accept Inbound Orders Routed by Archipelago Securities LLC in its Capacity as a Facility of Affiliated Exchanges and To... permanent the pilot program that permits the Exchange to accept inbound orders routed by Archipelago...

  16. 76 FR 62119 - Self-Regulatory Organizations; NYSE Arca, Inc; Order Approving a Proposed Rule Change Amending...

    Science.gov (United States)

    2011-10-06

    ... Rule 7.45(c)(2) To Make Permanent the Pilot Program That Permits the Exchange To Accept Inbound Orders Routed by Archipelago Securities LLC in Its Capacity as a Facility of Affiliated Exchanges and To Clarify... program that permits the Exchange to accept inbound orders routed by Archipelago Securities LLC (``Arca...

  17. 76 FR 53509 - Self-Regulatory Organizations; NYSE Arca, Inc.; Notice of Filing of Proposed Rule Change Amending...

    Science.gov (United States)

    2011-08-26

    ... Equities Rule 7.45(c)(2) To Make Permanent the Pilot Program That Permits the Exchange To Accept Inbound Orders Routed by Archipelago Securities LLC in Its Capacity as a Facility of Affiliated Exchanges and To... permanent the pilot program that permits the Exchange to accept inbound orders routed by Archipelago...

  18. 76 FR 53513 - Self-Regulatory Organizations; New York Stock Exchange LLC; Notice of Filing of Proposed Rule...

    Science.gov (United States)

    2011-08-26

    ... Rule 17(c)(2)(B) To Make Permanent the Pilot Program That Permits the Exchange To Accept Inbound Orders Routed by Archipelago Securities LLC in Its Capacity as a Facility of Affiliated Exchanges and To Clarify... the pilot program that permits the Exchange to accept inbound orders routed by Archipelago Securities...

  19. 76 FR 53516 - Self-Regulatory Organizations; NYSE Amex LLC; Notice of Filing of Proposed Rule Change Amending...

    Science.gov (United States)

    2011-08-26

    ... Rule 993NY(b)(2) To Make Permanent the Pilot Program That Permits the Exchange To Accept Inbound Orders Routed by Archipelago Securities LLC in Its Capacity as a Facility of Affiliated Exchanges and To Clarify...(b)(2) to make permanent the pilot program that permits the Exchange to accept inbound orders routed...

  20. 76 FR 53511 - Self-Regulatory Organizations; NYSE Amex LLC; Notice of Filing of Proposed Rule Change Amending...

    Science.gov (United States)

    2011-08-26

    ... Rule 17(c)(2)(B) To Make Permanent the Pilot Program that Permits the Exchange To Accept Inbound Orders Routed by Archipelago Securities LLC in Its Capacity as a Facility of Affiliated Exchanges and To Clarify... make permanent the pilot program that permits the Exchange to accept inbound orders routed by...

  1. 76 FR 62125 - Self-Regulatory Organizations; NYSE Amex LLC; Order Approving a Proposed Rule Change Amending...

    Science.gov (United States)

    2011-10-06

    ... Rule 993NY(b)(2) To Make Permanent the Pilot Program that Permits the Exchange To Accept Inbound Orders Routed by Archipelago Securities LLC in Its Capacity as a Facility of Affiliated Exchanges and To Clarify... program that permits the Exchange to accept inbound orders routed by Archipelago Securities LLC (``Arca...

  2. 76 FR 62116 - Self-Regulatory Organizations; NYSE Amex LLC; Order Approving a Proposed Rule Change Amending...

    Science.gov (United States)

    2011-10-06

    ... Rule 17(c)(2)(B) To Make Permanent the Pilot Program That Permits the Exchange To Accept Inbound Orders Routed by Archipelago Securities LLC in Its Capacity as a Facility of Affiliated Exchanges and To Clarify... program that permits the Exchange to accept inbound orders routed by Archipelago Securities LLC (``Arca...

  3. 76 FR 62122 - Self-Regulatory Organizations; New York Stock Exchange LLC; Order Approving a Proposed Rule...

    Science.gov (United States)

    2011-10-06

    ... Rule 17(c)(2)(B) To Make Permanent the Pilot Program That Permits the Exchange To Accept Inbound Orders Routed by Archipelago Securities LLC in Its Capacity as a Facility of Affiliated Exchanges and To Clarify... existing pilot program that permits the Exchange to accept inbound orders routed by Archipelago Securities...

  4. 78 FR 6161 - Self-Regulatory Organizations; NYSE Arca, Inc.; Order Granting Approval of Proposed Rule Change...

    Science.gov (United States)

    2013-01-29

    ... of the ``generic'' listing requirements of Commentary .01(a)(A) to NYSE Arca Equities Rule 5.2(j)(3..., the NASDAQ Global Select Market, the NASDAQ Select Market, and the NASDAQ Capital Market. Business... a covered call strategy. It consists of long positions in companies in the Reference Index and out...

  5. 77 FR 52776 - Self-Regulatory Organizations; NYSE Arca, Inc.; Notice of Filing of Proposed Rule Change Relating...

    Science.gov (United States)

    2012-08-30

    ... funds). In addition, the Commission has approved NYSE Arca generic listing rules for Units based on a... Strategy Fund and PIMCO Intermediate Municipal Bond Strategy Fund, among others). The Commission has... a market value weighted index and is rebalanced after the close on the last business day of each...

  6. 75 FR 76505 - Self-Regulatory Organizations; Notice of Filing and Immediate Effectiveness of a Proposed Rule...

    Science.gov (United States)

    2010-12-08

    ... days will not be counted toward the calculation of certain Investor Support Program (``ISP'') credit... of certain ISP credit eligibility requirements pursuant to subsection (c)(2) of the rule... its ISP- designated ports and executed in the Nasdaq Market Center during the month. The Exchange...

  7. 78 FR 15394 - Self-Regulatory Organizations; New York Stock Exchange LLC; Order Approving Proposed Rule Change...

    Science.gov (United States)

    2013-03-11

    ... inbound and outbound routing of certain orders. See NYSE Rule 17(c). The Exchange also has a joint venture... required unless the Respondent establishes that the failure to make the Document available was not harmless... Directors, would determine whether the failure to make the document available was not harmless error...

  8. 78 FR 5213 - Self-Regulatory Organizations; New York Stock Exchange LLC; Notice of Filing of Proposed Rule...

    Science.gov (United States)

    2013-01-24

    ... or the Act, making a material misstatement, or engaging in manipulation. NYSE Rule 476(b) describes... respondent to inspect and copy documents or records in the possession of the Exchange that are material to... material and that there was reasonable ground [sic] for failure to adduce it before the Hearing Panel or...

  9. 75 FR 65263 - Virginia Graeme Baker Pool and Spa Safety Act; Public Accommodation; Withdrawal of Proposed Rule

    Science.gov (United States)

    2010-10-22

    ...'' or ``Act'') as ``an inn, hotel, motel, or other place of lodging, except for an establishment located... interpretive rule to interpret ``public accommodations facility'' in the VGB Act as ``an inn, hotel, motel, or... CONSUMER PRODUCT SAFETY COMMISSION 16 CFR Part 1450 Virginia Graeme Baker Pool and Spa Safety Act...

  10. 75 FR 2902 - Self-Regulatory Organizations; NASDAQ OMX PHLX, Inc.; Notice of Filing of Proposed Rule Change by...

    Science.gov (United States)

    2010-01-19

    ... market activity altogether. In today's evolving regulatory climate, the Exchange believes that the... SECURITIES AND EXCHANGE COMMISSION [Release No. 34-61326; File No. SR-Phlx-2009-113] Self... Securities Exchange Act of 1934 (``Act'') \\1\\ and Rule 19b-4 thereunder,\\2\\ notice is hereby given that on...

  11. 77 FR 27254 - Self-Regulatory Organizations; ICE Clear Europe Limited; Order Approving Proposed Rule Change To...

    Science.gov (United States)

    2012-05-09

    ... respect of the Clearing Member's Proprietary Account and any relevant customer account. Where the Daily...\\ requires, among other things, that the rules of a clearing agency be designed to promote the safeguarding... safeguarding of securities and funds, which are in the custody or control of ICE Clear Europe or for which it...

  12. 78 FR 18386 - Self-Regulatory Organizations; NASDAQ OMX PHLX LLC; Notice of Filing of Proposed Rule Change To...

    Science.gov (United States)

    2013-03-26

    ... posted order. Thus, if 100 shares of an incoming order to buy 200 shares are designated to execute... not intend to buy shares that it is simultaneously selling. The revisions to the rule retain this logic, but give the Participant additional choice as to how the conflict should be resolved. First, the...

  13. 77 FR 22042 - Self-Regulatory Organizations; The NASDAQ Stock Market LLC; Notice of Filing of Proposed Rule...

    Science.gov (United States)

    2012-04-12

    ... Quality Program is implemented by the Exchange and an MQP Company \\5\\ and one or more related Market... rules related to the qualification, listing, and delisting of Companies on the NASDAQ Stock Market. The... prior to hiring a market maker * * * [have] a high loading on a liquidity risk factor, experience a...

  14. 75 FR 51960 - Proposed Rule To Implement the 1997 8-Hour Ozone National Ambient Air Quality Standard: New...

    Science.gov (United States)

    2010-08-24

    ... South Severe-17 Los Angeles South Extreme. Coast Air Basin, Coast Air Basin, CA. CA. CA Los Angeles-San.... Anti-Backsliding Provisions B. Reconsideration of Certain Provisions of the Phase 1 Rule C. South Coast... was revoked. C. South Coast Decision In South Coast Air Quality Management District, et al., v. EPA...

  15. 78 FR 12125 - Self-Regulatory Organizations; ICE Clear Credit LLC; Notice of Filing of Proposed Rule Change To...

    Science.gov (United States)

    2013-02-21

    ... within Chapter 5 (Risk Committee) of the ICC Rules. This update will provide direct reference within the... financial single names, additional single- name constituents of the Emerging Markets Index, and High Yield... Services, Energy, Financials, Healthcare, Industrials, Technology, Telecommunications Services, and...

  16. 78 FR 19790 - Self-Regulatory Organizations; ICE Clear Credit LLC; Order Approving Proposed Rule Change, as...

    Science.gov (United States)

    2013-04-02

    ... includes a conforming edit within Chapter 5 (Risk Committee) of the ICC Rules. This update will provide... circumstances (e.g., certain financial single names, additional single- name constituents of the Emerging..., Energy, Financials, Healthcare, Industrials, Technology, Telecommunications Services, and Utilities. The...

  17. 76 FR 16650 - Self-Regulatory Organizations; NASDAQ OMX BX, Inc.; Order Approving Proposed Rule Change To Amend...

    Science.gov (United States)

    2011-03-24

    ... heterogeneously informed agents,'' Journal of Financial Economics 14 (1985), at 71-100; and Copeland, T., and D... whether to provide price improvement to a particular order. \\11\\ See also Rule 723 of the International..., H. R., ``The supply of dealer services in securities of markets,'' Journal of Finance 33 (1978), at...

  18. 78 FR 55312 - Self-Regulatory Organizations; NYSE Arca, Inc.; Notice of Filing of a Proposed Rule Change...

    Science.gov (United States)

    2013-09-10

    ... or different across all exchanges trading the same option? What are the advantages and disadvantages...: Electronic Comments Use the Commission's Internet comment form ( http://www.sec.gov/rules/sro.shtml ); or... method. The Commission will post all comments on the Commission's Internet Web site ( http://www.sec.gov...

  19. 77 FR 75459 - Self-Regulatory Organizations; BATS Exchange, Inc.; Notice of Filing of a Proposed Rule Change To...

    Science.gov (United States)

    2012-12-20

    ... Information'' in order to both make clear that the rule should apply to IPO Auctions and to make a change to... public offering auction (an ``IPO Auction''), and an auction in the event of a halt of trading in the... requirements should apply to both IPO Auctions and Halt Auctions, and to make a change to the data that will be...

  20. 76 FR 67238 - Self-Regulatory Organizations; BATS Exchange, Inc.; Order Approving Proposed Rule Change by BATS...

    Science.gov (United States)

    2011-10-31

    ... offering (``IPO Auction''); and (4) an auction in the event of a halt of trading in a security (``Halt Auction''). The Opening Auction, IPO Auction, Halt Auction, and Closing Auction operated by BATS will be a... the Opening Auction, the Closing Auction, and IPO/Halt Auctions. \\8\\ BATS Rule 1.5(w) defines...

  1. 77 FR 73500 - Self-Regulatory Organizations; NYSE Arca, Inc.; Notice of Filing of Proposed Rule Change Relating...

    Science.gov (United States)

    2012-12-10

    ... (``REITs'') are eligible for inclusion as equity securities, with the exception of mortgage REITs... Call ETF, and Horizons S&P Energy Select Sector Covered Call ETF Under NYSE Arca Equities Rule 5.2(j)(3... Sector Covered Call ETF, and Horizons S&P Energy Select Sector Covered Call ETF under NYSE Arca Equities...

  2. 76 FR 38712 - Self-Regulatory Organizations; BATS Exchange, Inc.; Order Approving a Proposed Rule Change To...

    Science.gov (United States)

    2011-07-01

    ... to BATS Rule 11.13 to state that the Exchange will consider it inconsistent with just and equitable... the very inside of the market but are temporarily un-executable at their full limit price due to the... price improvement for market participants at times when such participants are not receiving executions...

  3. 77 FR 50734 - Self-Regulatory Organizations; NYSE MKT LLC; Order Approving a Proposed Rule Change Amending the...

    Science.gov (United States)

    2012-08-22

    ... Rule 900.2NY(77); and (iii) non-ATP Holder broker-dealers and vendors that request to receive co...-2010-101). \\5\\ For purposes of its co-location services, the term ``User'' includes (i) ``ATP Holders... cabinet space, in which the power is not utilized, of $360 per month. III. Discussion and Commission's...

  4. 77 FR 66209 - Self-Regulatory Organizations; ICE Clear Europe Limited; Notice of Filing of Proposed Rule Change...

    Science.gov (United States)

    2012-11-02

    ... Spain (the ``New Sovereign Contracts''). II. Self-Regulatory Organization's Statement of the Purpose of... the termination of relevant positions. The margin model applicable to New Sovereign Contracts will use... Comments Use the Commission's Internet comment form ( http://www.sec.gov/rules/sro.shtml ); or Send an...

  5. 75 FR 10851 - Self-Regulatory Organizations; NYSE Amex LLC; Notice of Filing of Proposed Rule Change Relating...

    Science.gov (United States)

    2010-03-09

    ...\\6\\ and to provide competitive pricing. \\4\\ See NYSE Amex Rule 900.2NY(18). \\5\\ See, e.g., NYSE Amex... pricing models based on real-time streaming data, access to multiple markets simultaneously, and order and... theoretical value of the option, which moves with various factors in their pricing models, such as the value...

  6. 77 FR 59995 - Self-Regulatory Organizations; NYSE Arca, Inc.; Notice of Filing of Proposed Rule Change Amending...

    Science.gov (United States)

    2012-10-01

    ... Rule 1.1(q). \\6\\ OTP Firm means a sole proprietorship, partnership, corporation, limited liability... Incorporation and Sections 3.02, 4.01, and 4.02 of the NYSE Arca Equities Bylaws. \\22\\ ETP Holder means a sole proprietorship, partnership, corporation, limited liability company or other organization in good standing that...

  7. 75 FR 42804 - Self-Regulatory Organizations; Notice of Filing of Proposed Rule Change by NASDAQ OMX PHLX, Inc...

    Science.gov (United States)

    2010-07-22

    ... Registered Principals.\\18\\ Specifically, an Exchange member organization, except a sole proprietorship, shall... securities business, (2) who is no longer functioning as a representative, or (3) where the sole purpose is... Principal, or (3) where the sole purpose is to avoid the examination requirement of this rule. A member...

  8. 77 FR 13668 - Self-Regulatory Organizations; NASDAQ OMX PHLX LLC; Notice of Filing of Proposed Rule Change To...

    Science.gov (United States)

    2012-03-07

    ... organization for any of these functions are principals. Such persons shall include: sole proprietors, officers... be contained in new Rule 611(e).\\27\\ Specifically, an Exchange member organization, except a sole proprietorship, shall have at least two officers or partners who are registered as principals with respect to...

  9. 77 FR 64167 - Self-Regulatory Organizations; The NASDAQ Stock Market LLC; Notice of Filing of Proposed Rule...

    Science.gov (United States)

    2012-10-18

    ... Stocks (as defined in Rule 5705), changes in the intraday net asset value (``INAV''), as appropriate. A... Portfolio Value (IPV) amongst others. The INAV is intended to approximate the fair value of the securities... values do not change, particularly in periods of low volatility. Additionally, the INAV may become stale...

  10. 77 FR 67722 - Self-Regulatory Organizations; BOX Options Exchange LLC; Notice of Filing of Proposed Minor Rule...

    Science.gov (United States)

    2012-11-13

    ... final or such determination must be contested. If the person against whom the fine is imposed pays the... contest the Exchange's determination by filing with the Exchange a written answer, at which point the... individual and/or organization, the nature of the violation, the specific rule provision violated, the...

  11. 78 FR 62841 - Self-Regulatory Organizations; NASDAQ OMX BX, Inc.; Notice of Filing of Proposed Rule Change To...

    Science.gov (United States)

    2013-10-22

    ... million, shares of liquidity during the month, which is a higher rate than the base rate of $0.0007 per... SECURITIES AND EXCHANGE COMMISSION [Release No. 34-70655; File No. SR-BX-2013-054] Self-Regulatory... Exchange Rule 7018(a) With Respect to Transactions in Securities Priced at $1 per Share or Greater October...

  12. 75 FR 82106 - Self-Regulatory Organizations; NYSE Arca, Inc.; Order Granting Approval of Proposed Rule Change...

    Science.gov (United States)

    2010-12-29

    ..., risks, fees and expenses, creation and redemption procedures, portfolio holdings and policies... addition, an estimated value, defined in NYSE Arca Equities Rule 8.600 as the ``Portfolio Indicative Value,'' that reflects an estimated intra-day value of the Fund's portfolio, will be disseminated. The Portfolio...

  13. 75 FR 47323 - Self-Regulatory Organizations; NYSE Arca, Inc.; Order Granting Approval of Proposed Rule Change...

    Science.gov (United States)

    2010-08-05

    ... redemptions of the Shares, investment risks, NAV calculation, the dissemination of key values and availability... assets. In addition, an estimated value that reflects an estimated intraday value of the Fund's portfolio, defined in NYSE Arca Equities Rule 8.600 as the ``Portfolio Indicative Value,'' will also be disseminated...

  14. 76 FR 62112 - Self-Regulatory Organizations; NYSE Arca, Inc.; Order Granting Approval of Proposed Rule Change...

    Science.gov (United States)

    2011-10-06

    ... risk by maintaining an aggregate portfolio duration of between two and eight years under normal market... Portfolio Indicative Value, as defined in NYSE Arca Equities Rule 8.600(c)(3), will be updated and widely... Fixed Income Securities in the Fund's portfolio are closed, the Portfolio Indicative Value will be...

  15. 76 FR 8388 - Self-Regulatory Organizations; NYSE Arca, Inc.; Order Approving a Proposed Rule Change To List...

    Science.gov (United States)

    2011-02-14

    ... investment strategies, risks, creation and redemption procedures, fees, portfolio holdings and disclosure..., defined in NYSE Arca Equities Rule 8.600 as the Portfolio Indicative Value (``PIV'') that reflects an estimated intraday value of the ETF's portfolio, will be updated and disseminated by [[Page 8389

  16. 76 FR 27127 - Self-Regulatory Organizations; NYSE Arca, Inc.; Notice of Filing of Proposed Rule Change To List...

    Science.gov (United States)

    2011-05-10

    ... relating to codes of ethics. This Rule requires investment advisers to adopt a code of ethics that reflects... other method of public dissemination. The Fund reserves the right to accept or pay out a basket of.... Trading may be halted because of market conditions or for reasons that, in the view of the Exchange, make...

  17. 78 FR 5518 - Self-Regulatory Organizations; NASDAQ OMX PHLX LLC; Notice of Filing of Proposed Rule Change To...

    Science.gov (United States)

    2013-01-25

    ... customer order (other than a stop or stop-limit order as defined in Rule 1066) to buy or sell which has..., capacity restrictions or other factors relevant to the maintenance of a fair and orderly market, the Board... Directors (``Board'') from a decision of the Exchange may be requested by a member or member organization...

  18. 78 FR 62751 - Self-Regulatory Organizations; NYSE Arca, Inc.; Notice of Filing of Proposed Rule Change To List...

    Science.gov (United States)

    2013-10-22

    .... \\10\\ Data for the global currencies is derived, in part, from the Bank for International Settlements..., and the WisdomTree Commodity Currency Bearish Fund Under NYSE Arca Equities Rule 8.600 October 8, 2013... Currency Bearish Fund (``CC Bear Fund,'' and collectively with the DI Funds, ``Funds''). The shares of the...

  19. 75 FR 6072 - Self-Regulatory Organizations; The NASDAQ Stock Market LLC; Order Approving Proposed Rule Change...

    Science.gov (United States)

    2010-02-05

    ... delisting process if such rule changes are found to benefit Nasdaq's financial position.\\46\\ [[Page 6075... SEC filing made by listing companies, including proxies and annual and quarterly financial reports... the changes that have taken place in the financial markets, the existing time periods are unreasonably...

  20. 75 FR 3948 - Self-Regulatory Organizations; The NASDAQ Stock Market LLC; Notice of Filing of Proposed Rule...

    Science.gov (United States)

    2010-01-25

    ..., Other than Paid Advertising) and 9810 (Initiation of Proceeding) to reflect recent changes to... Paid Advertising) and 9810 (Initiation of Proceeding) to update cross-references to corresponding rules...-FINRA-2009-078)(notice of filing and immediate effectiveness). \\5\\ See Securities Exchange Act Release...

  1. 78 FR 58364 - Self-Regulatory Organizations; BOX Options Exchange LLC; Notice of Filing of Proposed Rule Change...

    Science.gov (United States)

    2013-09-23

    ... Internet Web site at http://boxexchange.com . II. Self-Regulatory Organization's Statement of the Purpose... buy or sell an equal quantity of two options series resting on the Complex Order Book. \\9\\ See Rule... initially as follows: Orders for Strategy A+B: BOX Book Interest to buy 10 at $2.00 BOX Book Interest to...

  2. 78 FR 25774 - Self-Regulatory Organizations; The NASDAQ Stock Market LLC; Order Approving a Proposed Rule...

    Science.gov (United States)

    2013-05-02

    ...; real estate; intangible assets such as trademarks, copyrights and patents; and securities of... determined net asset value; and (c) when aggregated in the same specified minimum number, may be redeemed at... value equal to the next determined net asset value. See Nasdaq Rule 5735(c)(1). \\5\\ See Notice, supra...

  3. 17 CFR 240.19b-4 - Filings with respect to proposed rule changes by self-regulatory organizations.

    Science.gov (United States)

    2010-04-01

    ... and fairly implied by that rule. (e) For the purposes of this paragraph, new derivative securities product means any type of option, warrant, hybrid securities product or any other security, other than a single equity option or a security futures product, whose value is based, in whole or in part, upon the...

  4. 78 FR 71002 - Self-Regulatory Organizations; New York Stock Exchange LLC; Notice of Filing of Proposed Rule...

    Science.gov (United States)

    2013-11-27

    ... 19(b)(1) \\1\\ of the Securities Exchange Act of 1934 (the ``Act'') \\2\\ and Rule 19b-4 thereunder,\\3... believes that the incentives offered by the Program, in particular the balanced and limited segmentation of..., and much of it is through client segmentation whereby non-exchange venues are able to incentivize...

  5. 78 FR 70992 - Self-Regulatory Organizations; NYSE MKT LLC; Notice of Filing of Proposed Rule Change to...

    Science.gov (United States)

    2013-11-27

    ... the Securities Exchange Act of 1934 (the ``Act'') \\2\\ and Rule 19b-4 thereunder,\\3\\ notice is hereby... segmentation of Institutional Interest and the Program's incorporation of price-size-time priority, have the... order handling practices, and much of it is through client segmentation whereby non-exchange venues are...

  6. 77 FR 15440 - Self-Regulatory Organizations; NYSE Arca, Inc.; Order Granting Approval of Proposed Rule Change...

    Science.gov (United States)

    2012-03-15

    ... policies or regulatory or tax law requirements. ProShares UltraPro Australian Dollar, ProShares UltraPro... including: Austria, Belgium, Cyprus, Estonia, Finland, France, Germany, Greece, Ireland, Italy, Luxembourg... Index or changes to the U.S. Dollar Index methodology in violation of applicable laws, rules, or...

  7. 75 FR 47652 - Self-Regulatory Organizations; NYSE Arca, Inc.; Order Granting Approval of a Proposed Rule Change...

    Science.gov (United States)

    2010-08-06

    ... August 2, 2010. I. Introduction On June 10, 2010, NYSE Arca, Inc. (``Exchange'' or ``NYSE Arca''), filed... Rule specifically requires the adoption of a code of ethics by an investment adviser to include, at a... supervised persons to report any violations of the code of ethics promptly to the chief compliance officer...

  8. 77 FR 62541 - Self-Regulatory Organizations; New York Stock Exchange LLC; Notice of Filing of Proposed Rule...

    Science.gov (United States)

    2012-10-15

    ... business or personal relationship of the compensation consultant, legal counsel, other adviser or the... standards satisfy the requirements of the final rule; a discussion of the exchange's consideration of... revenues. For purposes of Sections 303A.01, 303A.03, 303A.04, 303A.05 and 303A.09, a director of a business...

  9. 77 FR 51088 - Self-Regulatory Organizations; NASDAQ OMX PHLX LLC; Notice of Filing of Proposed Rule Change...

    Science.gov (United States)

    2012-08-23

    ... securities'' (also known as Treasury debt securities) means a bond or note or other evidence of indebtedness... are organized as noted. Generally, rules applicable to equity and currency options can currently be... databases providing bond information, including information regarding the listing and/or trading location of...

  10. 75 FR 81697 - Self-Regulatory Organizations; NYSE Arca, Inc.; Notice of Filing of Proposed Rule Change Relating...

    Science.gov (United States)

    2010-12-28

    ... investment types (equities, bonds, etc.), global regions, countries, styles (market capitalization, value... diversified exposure to various investment types (equities, bonds, etc.), global regions, countries, styles... and trade the following Managed Fund Shares under NYSE Arca Equities Rule 8.600: SiM Dynamic...

  11. Proposed reductions of preventable deaths in rural Indonesia through stormwater harvesting and wastewater treatment

    Directory of Open Access Journals (Sweden)

    Shane Elson

    2013-02-01

    Full Text Available Worldwide, what is responsible for killing the most children each year? AcuteRespiratory Infection (2 million children. What is second? Diarrhoea (1.8 million children. Thisstatistic does not include the additional 300,000 adults who also die from this preventable condition.Diarrhoea kills more children that malaria, HIV and measles combined (UNDP, 2006. “In most ofthe developing world, unclean water is a greater threat to human lives than violent conflict. Rightnow almost half the population of the developing world suffer from diseases because of dirty waterand inadequate sanitation” (Peace Child International, 2006. While the Millennial DevelopmentGoals (MDG and the United Nations provide an overarching view of the existing situations bycountry, the initial goal of this project is to investigating the specific existing conditions in ruralIndonesia, especially Southern Kalimantan, and how they relate to the MDG (UNDP, 2003.This will in turn allow site specific proposals in partnership with the local communities that areculturally and financially feasible. They will then be designed and constructed in conjunctionwith community education. The preliminary proposal is to use stormwater harvesting to providea clean water source in replacement of their current sources; seasonal wells, contaminated riversand swamps. In conjunction is the proposal to eliminate their exposure to open sewage throughsimple septic systems. Through these processes, the goal is to decrease the preventable cases ofsickness through increased access to clean up and decreased exposure to open sewage. This in turnwill reduce the associated deaths due to diarrhoea (WHO/UNICEF, 2009. The project is still inthe initial research and development stages as of March 2012 with the first project hoping to beundertaken by the end of 2012.

  12. Towards flash flood disaster prevention: the SciNetNat Haz proposal

    Science.gov (United States)

    Konstantinos, Papatheodorou; Elena, Tzanou; Carmen, Maftei; Ozgur, Kirca; Hafzullah, Aksoy

    2015-04-01

    Floods occur with a continuously increasing frequency due to climatic changes and cause serious damage in the wider Black Sea area, endangering human life and property. As societies continuously expand, these phenomena are expected to play an increasingly important role, blocking sustainable development unless properly tackled. Flash flood prevention seems at this point, to be the target of effectively mitigating the potential threat. Since in many cases, there is a cross-border character of the problem, collaborative efforts have to be made involving cooperation between countries. To this end, a variety of problems exist, including the "information gap" related to the unavailability of data and the multitude of methodologies used to assess flood hazard; a fact that renders comparison of hazard assessment results and cross border cooperation ineffective. An effort made within the context of the SciNetNatHaz project, suggests a two step approach to produce reliable the results which can lead to decision making regarding designing preventive measures. The first step aims at defining the flood prone areas on a regional scale, using geomorphometric models and readily available topographic data; thus overcoming the problem of data availability for any region of interest. The second step follows a vulnerability and risk assessment of the flood prone areas of interest and focuses on the calculation of flood parameters on a local scale using hydraulic models. Implementation of the full process is based on Open Source software tools so that it can be implemented with minimal costs by anyone interested. Implementation of the proposed procedure in three different cases in Greece and in Romania shows that it can provide accurate and reliable results to support decision making regarding the design of preventive measures. Keywords: Flash floods, hazard assessment, flood disaster prevention, HEC-RAS, SAGA GIS . Acknowledgements: This work is partially funded by the EU through the

  13. 77 FR 50671 - Withdrawal of Proposed Rule on Insurer Reporting Requirements; List of Insurers Required To File...

    Science.gov (United States)

    2012-08-22

    ... of Transportation to promulgate a Theft Prevention Standard for selected passenger cars exhibiting... through an affiliate, including pooling arrangements established under state law or regulation for the...

  14. The impact of preventive maintenance practices on manufacturing performance: A proposed model for SMEs in Malaysia

    Science.gov (United States)

    Lazim, Halim Mad; Taib, Che Azlan; Lamsali, Hendrik; Saleh, Mohamed Najib; Subramaniam, Chandrakantan

    2016-08-01

    Preventive maintenance (PM) plays important role to avoid or mitigate potential stoppages and disruptions of equipment or machinery from occurring in daily operations. PM emphasized total employee involvement and it is important for companies as well as Small and Medium Sized Enterprises (SMEs). SME sectors contribution to the Malaysian economy makes up 95% of the total manufacturers, however PM remain relatively lacking. The ability, reliability and effective maintenance management is highly important in order to achieve desired manufacturing performance. Therefore, organizational capability in planning, controlling, implementing and monitoring PM activities is important. Furthermore, empirical evidence on the potential impact of PM practices towards manufacturing performance with organizational capability as a moderating effect is still limited and indecisive. Henceforth, this paper aims to explore and investigate potential relationships between PM practices and manufacturing performance moderated by organizational capability in the contact of Malaysian SMEs in the manufacturing sector. Correspondently, the study intends to propose a new research framework and hypotheses to examine the abovementioned relationships. The proposed framework includes PM team, PM strategy and planned maintenance as the determinants, while organizational capability serves as the moderating variable. Manufacturing performance will be viewed in terms of innovation and financial factors. Proposed research direction and conclusion are discussed at the end of the study.

  15. Prediction of Clinically Important Traumatic Brain Injury in Pediatric Minor Head Trauma; proposing Pediatric Traumatic Brain Injury (PTBI Prognostic Rule

    Directory of Open Access Journals (Sweden)

    Babak Nakhjavan-Shahraki

    2017-01-01

    Full Text Available Background: The present study assesses independent predictors of clinically important traumatic brain injury (ciTBI in order to design a prognostic rule for identification of high risk children with mild head injury. Materials and Methods: In a retrospective cross-sectional study, 3,199 children with mild traumatic brain injury (TBI brought to emergency ward of three hospitals in Tehran, Iran were gathered, from April 2014 to April 2016. The associations between probable predictors of ciTBI in children with mild TBI were assessed and a prediction rule for identification of high risk children in need of computed tomography (CT scan was designed based on a stepwise multivariate logistic regression. Results: 592 (18.5% children had ciTBI. History of loss of conciseness (odds ratio [OR]=3.0; p

  16. Quality assurance in central nuclear power plant control systems. (Status report containing proposed enhancements for KTA rules)

    International Nuclear Information System (INIS)

    Gossner, S.

    1985-01-01

    All enterprises investigated observe the requirements laid down in KTA 1401. In most cases, the quality assurance systems and measures applied even go beyond the requirements of KTA 1401, especially in those enterprises working primarily for export and having to meet foreign quality assurance standards. Quality assurance measures in these enterprises are based primarily on 10 CFR 50, App.B and related rules and standards (e.g. ANSI N 54.2; NUREG 75/087). Internal quality assurance in these enterprises is organized on the basis of graphic flow diagrams which are even presented in the quality assurance manuals. These flow diagrams, in contrast to the German KTA rules, meet the international standards for quality assurance. KTA 1401 requirements not sufficiently met are, e.g. the operator audits with plant producers and unit and equipment producer audits with component producers. The report presents hints for improvements of the quality assurance concept in control systems engineering. (orig./HP) [de

  17. Academic stress in Chinese schools and a proposed preventive intervention program

    Directory of Open Access Journals (Sweden)

    Xu Zhao

    2015-12-01

    Full Text Available While American educators fret about the mediocre educational performance of American students in international contests (e.g. the Program for International Student Assessment and wonder why the Chinese education system produces such high-achieving students, educators, journalists, and public officials in China want to know what causes and how to prevent the high levels of academic stress that Chinese students, their families, and their school systems experience. So far, much of the blame for these toxic levels of stress has been directed to the Gaokao, the Chinese national college entrance exam that takes place in June each year. But to date, top-down Chinese educational reforms have been ineffective in reducing the problem. In this article, we build a case for strengthening bottom-up efforts at the school level in China and propose an evidence-based approach for addressing the challenge of academic stress experienced by Chinese students.

  18. Rule of Thumb Proposing the Size of Aperture Expected to be Sufficient to Resolve Double Stars with Given Parameters

    Science.gov (United States)

    Knapp, Wilfried

    2018-01-01

    Visual observation of double stars is an anachronistic passion especially attractive for amateurs looking for sky objects suitable for visual observation even in light polluted areas. Session planning then requires a basic idea which objects might be suitable for a given equipment—this question is a long term issue for visual double star observers and obviously not easy to answer, especially for unequal bright components. Based on a reasonably large database with limited aperture observations (done with variable aperture equipment iris diaphragm or aperture masks) a heuristic approach is used to derive a statistically well founded Rule of Thumb formula.

  19. 77 FR 3021 - Self-Regulatory Organizations; The NASDAQ Stock Market LLC; Notice of Filing of Proposed Rule...

    Science.gov (United States)

    2012-01-20

    ... intangible assets and liabilities) in excess of $2,000,000, if the issuer has been in continuous operation... would also have to satisfy the proposed net tangible assets or revenue test,\\12\\ which is not a... addition, a company qualifying under the proposed standard must have either: (a) Net tangible assets in...

  20. Disruptive Influences on Research in Academic Pathology Departments: Proposed Changes to the Common Rule Governing Informed Consent for Research Use of Biospecimens and to Rules Governing Return of Research Results.

    Science.gov (United States)

    Sobel, Mark E; Dreyfus, Jennifer C

    2017-01-01

    Academic pathology departments will be dramatically affected by proposed United States federal government regulatory initiatives. Pathology research will be substantially altered if proposed changes to the Common Rule (Code of Federal Regulations: Protection of Human Subjects title 45 CFR 46) and regulations governing the return of individual research results are approved and finalized, even more so now that the Precision Medicine initiative has been launched. Together, these changes are disruptive influences on academic pathology research as we know it, straining limited resources and compromising advances in diagnostic and academic pathology. Academic research pathologists will be challenged over the coming years and must demonstrate leadership to ensure the continued availability of and the ethical use of research pathology specimens. Copyright © 2017 American Society for Investigative Pathology. Published by Elsevier Inc. All rights reserved.

  1. Watercraft and watersport injuries in children: trauma mechanisms and proposed prevention strategies.

    Science.gov (United States)

    Keijzer, Richard; Smith, Geni F; Georgeson, Keith E; Muensterer, Oliver J

    2013-08-01

    Watercraft-associated trauma (WAT) in children has received little attention so far, despite the potentially severe and debilitating resulting injuries. The aim of this study was to evaluate all cases of major watercraft-associated trauma admitted to the Children's of Alabama during the past 10 years, identify patterns in mechanism and injury, and propose future prevention strategies. We reviewed our (prospective) database for children admitted through our trauma center after major WAT. Charts were abstracted for mechanism, epidemiologic data, injury type and injury severity scale (ISS), as well as outcome. We identified 15 children (6 males, 9 females, age range 7 to 15, mean 12 ± 2 years), involved in 14 accidents. Sharp trauma was inflicted by a propeller (n=4) or a rope (n=1). Towed tubing (riding an inflatable tube while being pulled by a boat) was the most prevalent mechanism (n=6). There was a trend towards higher ISS after towed tubing (24.8 ± 12.4) compared to all other mechanisms (15.1±7.7). Mean length of stay was longer after towed tubing accidents (14.2 ± 7.2 versus 4.9 ± 3.4 days). All patients survived and eventually were discharged home. In one of the incidences, involving 2 victims of this series, the driver of the boat was intoxicated with alcohol. Pediatric watercraft-related accidents are infrequent, but often result in major injuries. More awareness for safety measures to prevent these injuries is warranted. Alcohol is not a major factor in pediatric watercraft-associated trauma. Tubes towed by a boat seem to be particularly dangerous, perhaps because of the rider's limited maneuverability and the fact that centrifugal force lets the tube travel well outside the wake in curves. Limiting boat speed and the use of protective gear on towed tubes when children are involved may decrease the incidence and severity of pediatric WAT. Copyright © 2013 Elsevier Inc. All rights reserved.

  2. 78 FR 50358 - Notice of Intent To Prepare an Environmental Impact Statement for the Proposed Rule, Standards...

    Science.gov (United States)

    2013-08-19

    ... Escherichia. coli exceedance of the proposed standard occurred during 5 percent of the monitoring period with.../2013/5079/SIR2013-5079.pdf . Accessed July 30, 2013. Dated: August 13, 2013. Leslie Kux, Assistant...

  3. 78 FR 33136 - Self-Regulatory Organizations; BATS Y-Exchange, Inc.; Order Granting Approval to Proposed Rule...

    Science.gov (United States)

    2013-06-03

    ... retail brokers of implementing technology changes to identify orders as Retail or non-Retail. Furthermore... the proposal may cause an exponential increase in monitoring and recordkeeping burdens associated with...

  4. 75 FR 48391 - Self-Regulatory Organizations; NASDAQ OMX PHLX, Inc.; Order Approving a Proposed Rule Change...

    Science.gov (United States)

    2010-08-10

    ... them and pay the fees as detailed in the proposal. As represented by Phlx, these fees are uniform for... interest because it will provide greater transparency regarding the connectivity options available to...

  5. 75 FR 49543 - Self-Regulatory Organizations; The NASDAQ Stock Market LLC; Order Approving a Proposed Rule...

    Science.gov (United States)

    2010-08-13

    ... voluntarily request them and pay the fees as detailed in the proposal. As represented by NASDAQ, these fees... and the public interest because it will provide greater transparency regarding the connectivity...

  6. 78 FR 15392 - Self-Regulatory Organizations; The NASDAQ Stock Market LLC; Notice of Filing of Proposed Rule...

    Science.gov (United States)

    2013-03-11

    ... Alert to make clear that the ``substantially all'' language is meant to permit the presence of only... is designed to prevent fraudulent and manipulative acts and practices, to promote just and equitable... in securities, and to remove impediments to and perfect the mechanism of a free and open market and a...

  7. 78 FR 22360 - Self-Regulatory Organizations; C2 Options Exchange, Incorporated; Order Approving a Proposed Rule...

    Science.gov (United States)

    2013-04-15

    ... exchange be designed to prevent fraudulent and manipulative acts and practices, to promote just and equitable principles of trade, to remove impediments to and perfect the mechanism of a free and open market... appointments; (2) to make markets that, absent changed market conditions, will be honored in accordance with...

  8. 77 FR 40396 - Self-Regulatory Organizations; EDGA Exchange, Inc.; Notice of Filing of Proposed Rule Changes To...

    Science.gov (United States)

    2012-07-09

    ... designed to manage the financial, regulatory and other risks of this business activity. These controls... certain regulatory risk management controls that, among other things, prevent the entry of orders unless... have been pre- approved and authorized by the broker-dealer. These regulatory risk management controls...

  9. 77 FR 16879 - Self-Regulatory Organizations; NASDAQ OMX PHLX LLC; Order Granting Approval of Proposed Rule...

    Science.gov (United States)

    2012-03-22

    ... for free from sources such as http://finance.yahoo.com/ ; as well as from brokers with whom investors... equitable principles of trade, to foster cooperation and coordination with persons engaged in facilitating... prevent fraudulent and manipulative acts and practices, to promote just and equitable principles of trade...

  10. Federal old-age, survivors, and disability insurance; listing of impairments--mental disorders--SSA. Proposed rules.

    Science.gov (United States)

    1985-02-04

    These proposed amendments revise the medical evaluation criteria for mental disorders for the disability program in title II and title XVI of the Social Security Act. No substantial revisions have been made to these criteria since 1979. The proposed revisions reflect advances in medical treatment and in methods of evaluating certain mental impairments, and will provide up-to-date medical criteria for use in the evaluation of disability claims based on mental disorders.

  11. US Department of Energy response to standards for remedial actions at inactive uranium processing sites: Proposed rule

    International Nuclear Information System (INIS)

    1988-01-01

    The Title I groundwater standards for inactive uranium mill tailings sites, which were promulgated on January 5, 1983, by the US Environmental Protection Agency (EPA) for the Uranium Mill Tailings Remedial Action (UMTRA) Project, were remanded to the EPA on September 3, 1985, by the US Tenth Circuit Court of Appeals. The Court instructed the EPA to compile general groundwater standards for all Title I sites. On September 24, 1987, the EPA published proposed standards (52FR36000-36008) in response to the remand. This report includes an evaluation of the potential effects of the proposed EPA groundwater standards on the UMTRA Project, as well as a discussion of the DOE's position on the proposed standards. The report also contains and appendix which provides supporting information and cost analyses. In order to assess the impacts of the proposed EPA standards, this report summarizes the proposed EPA standards in Section 2.0. The next three sections assess the impacts of the three parts of the EPA standards: Subpart A considers disposal sites; Subpart B is concerned with restoration at processing sites; and Subpart C addresses supplemental standards. Section 6.0 integrates previous sections into a recommendations section. Section 7.0 contains the DOE response to questions posed by the EPA in the preamble to the proposed standards. 6 refs., 5 figs., 3 tabs

  12. Proposal of procedures to prevent errors in radiotherapy based in learned lessons of accidental expositions

    International Nuclear Information System (INIS)

    Bueno, Giselle Oliveira Vieira

    2007-01-01

    In order to consider some procedures to prevent errors in radiotherapy based in learned lessons of accidental expositions and in accordance with information contained in international reports elaborated by International Atomic Energy Agency (IAEA) and of the data base availability by the European group Radiation Oncology Safety Information System (ROSIS) on the events, a research of the occurred errors was performed. For the evaluation of the incidents a data base based in the ROSIS and added plus a parameter was created 'type of error'. All the stored data make possible the evaluation of the 839 incidents in terms of frequency of the type of error, the process of detention, the number of reached patients and the degree of severity. Of the 50 types of found errors, the type of error more frequently was 'incorrect treatment coordinate', confirmed with the data of literature and representing 28,96 por cent of the total of the incidents. The results showed 44,44 por cent are discovered at the moment of the treatment and that the process of verification of the fiche or clinical revision of the patient is a verification more occurred insurance and in 43,33 por cent of the searched events. The results indicated that more than 50 por cent of the incidents the severity degree are void and approximately 62 por cent a patient are affected during the accomplishment of the radiotherapy. This work showed that to analyze the data base according to methodology proposal for Klein et al.; for Reason, and Dunscombe et al. is interesting to insert more characteristic detailed in the data base such as: the number of fractions for affected patient, number of fields of treatment for fraction that was affected, shunting line of the prescribed dose and shunting line of the volume prescribed in all the registered in cadastral map events. Some causes exist that can lead the errors when patient they are submitted to the radiotherapy. Some measures can be taken so that these errors do not

  13. Proposal of a thermo-hygrometric assessment methodology for the preventive conservation of paper

    Directory of Open Access Journals (Sweden)

    Marí­a de la Paz Diulio

    2014-06-01

    Full Text Available A method is proposed for assessing the thermo-hygrometric quality of stack areas in libraries which considers the stability of the variables as a complement to the performance index calculation. The analysis was conducted using samples collected in libraries at the National University of La Plata in successive environmental monitoring campaigns during which temperature and relative interior and exterior humidity were measured. The result is a grid where the location of each evaluated space with respect to the axes indicates its status in relation to the two criteria that determine materials conservation: permanence within proper ranges of temperature and relative humidity and the daily variation of the same within a maximum admissible margin. A new grouping of the buildings was established in accordance with their ability to allow improvement measures to be taken that are applicable to the group. This procedure enables a deeper level of evaluation when the analysis according to performance index gives null results and prevents the understanding of other variables that positively influence paper conservation, as is the case with the stability of the values.

  14. 76 FR 9637 - Proposed Information Collection (Veteran Suicide Prevention Online Quantitative Surveys) Activity...

    Science.gov (United States)

    2011-02-18

    ... Collection (Veteran Suicide Prevention Online Quantitative Surveys) Activity: Comment Request AGENCY... prevention of suicide among Veterans and their families. DATES: Written comments and recommendations on the.... Abstract: VA's top priority is the prevention of Veterans suicide. It is imperative to reach these at-risk...

  15. 75 FR 21061 - Self-Regulatory Organizations; Chicago Stock Exchange, Inc.; Notice of Filing of Proposed Rule...

    Science.gov (United States)

    2010-04-22

    ... Organizations) of Article 3, we are replacing cross-reference to former Article II (Participants) with that of... Participant Personnel), we are replacing the reference to the definition of Principal Stockholders in former... and Trial Proceedings), we propose to update the cross references to former Article XII (Discipline...

  16. 77 FR 30576 - Self-Regulatory Organizations; NASDAQ OMX BX, Inc.; Notice of Filing of Proposed Rule Change With...

    Science.gov (United States)

    2012-05-23

    .... Error positions may result from a technical or systems issue that causes orders to be executed in the... System Issue Occurs and To Describe the Operation of an Error Account May 17, 2012. Pursuant to Section... of an error account for NES. BX will implement the proposed change upon approval by the Commission...

  17. 76 FR 49520 - Self-Regulatory Organizations; Chicago Stock Exchange, Inc.; Notice of Filing of Proposed Rule...

    Science.gov (United States)

    2011-08-10

    ... the potential use or misuse of post-trade clearing information to compromise the information barrier.... The Exchange proposes to add information barrier requirements for Institutional Brokers that wish to... trading floor) and could trade from any location. A customer order would be deemed to be on the Exchange...

  18. 78 FR 21681 - Self-Regulatory Organizations; NYSE Arca, Inc.; Notice of Filing of Proposed Rule Change and...

    Science.gov (United States)

    2013-04-11

    ... a sole proprietorship, partnership, corporation, limited liability company, or other organization in... of whom must be the individual trader of the LMM who is proposed to trade the ETP. If the LMM were.... Within two business days after the final LMM interview, the Exchange staff, in its sole discretion, would...

  19. 78 FR 60352 - Self-Regulatory Organizations; Notice of Filing and Immediate Effectiveness of a Proposed Rule...

    Science.gov (United States)

    2013-10-01

    ...-adjusted option series of each multiply listed option class allocated to it for 90% of the trading day. If... customers. The Exchange believes that its Market Makers would be disadvantaged without this proposed relief. Other Members and public customers would also be disadvantaged if Market Makers withdrew from...

  20. 77 FR 42780 - Self-Regulatory Organizations; NASDAQ OMX PHLX LLC; Notice of Filing of Proposed Rule Change...

    Science.gov (United States)

    2012-07-20

    ... certain trading and hedging strategies. Thus, weeklies may be attractive for retail trading strategies... strategies effectively via STOs,\\8\\ particularly in the current fast and volatile multi-faceted trading and... proposal, to allow execution of more effective trading and hedging strategies on the Exchange. See...

  1. 77 FR 45706 - Self-Regulatory Organizations; The NASDAQ Stock Market LLC; Notice of Filing of Proposed Rule...

    Science.gov (United States)

    2012-08-01

    ... the initial public offering (``IPO'') of Facebook, Inc. (``Facebook'' or ``FB'') on May 18, 2012. In the weeks since the Facebook IPO, Nasdaq has reviewed the events of May 18 with the goal of proposing... with the Facebook IPO process on May 18, 2012, and the impacts that those system difficulties had on...

  2. 78 FR 53181 - Self-Regulatory Organizations; New York Stock Exchange LLC; Order Approving Proposed Rule Change...

    Science.gov (United States)

    2013-08-28

    ..., the performance of the company's internal audit function. The proposed amendment would provide that if... Section 303A.00, the company's charter must provide that the committee will assist board oversight of the..., the audit committee must meet periodically with the company personnel primarily responsible for the...

  3. 78 FR 62889 - Self-Regulatory Organizations; New York Stock Exchange LLC; Notice of Filing of Proposed Rule...

    Science.gov (United States)

    2013-10-22

    ... consist of a combination of governance, risk, compliance and board tools for company directors and... proposes to include corporate governance tools and advisory services with a commercial value of approximately $45,000 annually (the ``Enhanced Package''), corporate governance tools with a commercial value of...

  4. 75 FR 69494 - Self-Regulatory Organizations; NYSE Arca, Inc.; Notice of Filing of Proposed Rule Change To List...

    Science.gov (United States)

    2010-11-12

    ... overlaps with trading in the United States, which is when OTC market trading in London, New York and other... institutions such as bullion banks and dealers for the trading of spot gold, as well as a feed of live..., the Exchange may propose to list and/or trade pursuant to unlisted trading privileges (``UTP...

  5. 77 FR 7558 - Withdrawal of Proposed Rule on Approval of Farm Credit System Lending Institutions in Federal...

    Science.gov (United States)

    2012-02-13

    ... recent difficulties in mortgage finance markets indicated reduced availability of housing credit in rural... System has been a source of consistent and reliable credit for rural homeowners and that the ability to... afoul of the Administration's proposal to reduce government involvement in the housing finance market...

  6. 76 FR 13251 - Self-Regulatory Organizations; New York Stock Exchange LLC; Notice of Filing of Proposed Rule...

    Science.gov (United States)

    2011-03-10

    ... its DMM. In that case, the selection is made by an Exchange Selection Panel (``ESP'') comprised of...\\ in particular in that it is designed to promote just and equitable principles of trade, to foster... when conducting their DMM activities, and the proposed amendments are consistent with Section 806.01 of...

  7. 78 FR 12123 - Self-Regulatory Organizations; NYSE MKT LLC; Notice of Filing of Proposed Rule Change Amending...

    Science.gov (United States)

    2013-02-21

    ... in Items I, II, and III below, which Items have been prepared by the self-regulatory organization... Exchange proposes to amend the times in which certain ATP Holders are required to notify the Exchange in... to extend the time ATP Holders acting as agent for Customer orders have to notify the Exchange of a...

  8. 76 FR 45885 - Self-Regulatory Organizations; NYSE Arca, Inc.; Notice of Filing of Proposed Rule Change To List...

    Science.gov (United States)

    2011-08-01

    ... participants in the soybean industry and other industries seeking to hedge the risk of losses in their soybean... of the Teucrium Wheat Fund, the Teucrium Soybean Fund and the Teucrium Sugar Fund Under NYSE Arca... proposes to list and trade shares of the Teucrium Wheat Fund, the Teucrium Soybean Fund and the Teucrium...

  9. 76 FR 75573 - Self-Regulatory Organizations; NASDAQ OMX BX, Inc.; Order Approving Proposed Rule Change With...

    Science.gov (United States)

    2011-12-02

    ... (``Board'') to determine the size of its Audit Committee, so long as the Audit Committee includes at least three directors, as well as the size of its Nominating & Governance Committee, so long as the Nominating & Governance Committee includes at least two directors. The proposal is intended to provide greater flexibility...

  10. 76 FR 75924 - Self-Regulatory Organizations; NASDAQ OMX PHLX LLC; Order Approving Proposed Rule Change To Amend...

    Science.gov (United States)

    2011-12-05

    ...'') to determine the size of its Audit Committee, so long as the Audit Committee includes at least three directors, as well as the size of its Nominating & Governance Committee, so long as the Nominating & Governance Committee includes at least two directors. The proposal is intended to provide greater flexibility...

  11. 76 FR 55148 - Self-Regulatory Organizations; BATS Exchange, Inc.; Order Approving Proposed Rule Change To Adopt...

    Science.gov (United States)

    2011-09-06

    ...) prepared in accordance with International Financial Reporting Standards, as issued by the International Accounting Standards Board, for Companies that are permitted to file financial statements using those... represents that the proposed standards for a security's initial and continued listing on Tier I are nearly...

  12. 78 FR 24449 - Self-Regulatory Organizations; BOX Options Exchange, LLC; Order Approving a Proposed Rule Change...

    Science.gov (United States)

    2013-04-25

    ... in the Price Improvement Period (``PIP'') auction; (vii) provide for the generation of Implied Orders... the display of Legging Orders, Complex Orders, and Implied Orders in BOX's proprietary High Speed...-Option Orders on BOX in the future. See id. In addition, BOX proposes to add the following defined terms...

  13. 78 FR 1281 - Self-Regulatory Organizations; ICE Clear Europe Limited; Notice of Filing of Proposed Rule Change...

    Science.gov (United States)

    2013-01-08

    ... changes in the recovery rate assumptions and their impact on the net asset value of the CDS portfolio... proposes to implement an enhanced margin methodology (``Decomp Model'') that addresses the risk of both... permits appropriate portfolio margining between related index and single-name CDS positions. II. Self...

  14. 78 FR 33457 - Self-Regulatory Organizations; The NASDAQ Stock Market LLC; Notice of Filing of a Proposed Rule...

    Science.gov (United States)

    2013-06-04

    ... continue to manage the Funds in the manner prescribed in the Prior Approval Orders, and will not implement..., and variable rate or floating rate securities which are readjusted on set dates (such as the last day... change occurs in the case of a floating rate instrument.\\18\\ The Adviser represents that these proposed...

  15. 76 FR 61463 - Self-Regulatory Organizations; NYSE Arca, Inc.; Notice of Filing of Proposed Rule Change Amending...

    Science.gov (United States)

    2011-10-04

    ... trading day begins.\\13\\ \\13\\ The Exchange and other markets will advise via Trader Update the specific... proposed amendments must strike the appropriate balance between permitting trading halts as late in the day....--one hour; at or after 2 p.m.--trading shall halt and not resume for the rest of the day. Level 3 Halt...

  16. 77 FR 63370 - Self-Regulatory Organizations; Chicago Stock Exchange, Inc.; Notice of Filing of Proposed Rule...

    Science.gov (United States)

    2012-10-16

    ... composed entirely of independent directors, subject to the general independence requirements of proposed... independent directors functioning within either formal committees of the board of directors or a non-committee... board of directors who oversee executive compensation matters on behalf of the board of directors, who...

  17. 75 FR 36765 - Self-Regulatory Organizations; EDGX Exchange, Inc.; Notice of Filing of Proposed Rule Change, as...

    Science.gov (United States)

    2010-06-28

    ... Guidelines or Reference Prices in various ``Unusual Circumstances.'' The Exchange proposes to replace this... reviews of Multi-Stock Events involving twenty or more securities, the Exchange may use a Reference Price... to the one or more specific points in time selected as the Reference Price. The Exchange will nullify...

  18. 75 FR 36743 - Self-Regulatory Organizations; Chicago Stock Exchange, Inc.; Notice of Filing of Proposed Rule...

    Science.gov (United States)

    2010-06-28

    ... or Reference Prices in various ``Unusual Circumstances.'' The Exchange proposes to replace this... reviews of Multi-Stock Events involving twenty or more securities, the Exchange may use a Reference Price... to the one or more specific points in time selected as the Reference Price. The Exchange will nullify...

  19. 75 FR 36762 - Self-Regulatory Organizations; EDGA Exchange, Inc.; Notice of Filing of Proposed Rule Change, as...

    Science.gov (United States)

    2010-06-28

    ... Guidelines or Reference Prices in various ``Unusual Circumstances.'' The Exchange proposes to replace this... Reference Price other than consolidated last sale in its review of potentially clearly erroneous executions... prior to the one or more specific points in time selected as the Reference Price. The Exchange will...

  20. 77 FR 35444 - Self-Regulatory Organizations; NYSE Amex LLC; Order Granting Approval of Proposed Rule Change...

    Science.gov (United States)

    2012-06-13

    ... meet the 5% average quoting requirement, and use of specified SLP mnemonics. In addition, the business... unique mnemonics specifically dedicated to SLMM activity. Use of these unique mnemonics will enable SLMMs... to the Exchange. As proposed, such mnemonics may not be used for trading in securities other than SLP...

  1. 77 FR 24239 - Self-Regulatory Organizations; New York Stock Exchange LLC; Notice of Filing of Proposed Rule...

    Science.gov (United States)

    2012-04-23

    ... requirement, and use of specified SLP mnemonics. In addition, the business unit of the member organization... to maintain unique mnemonics specifically dedicated to SLMM activity. Use of these unique mnemonics...-making activity to the Exchange. As proposed, such mnemonics may not be used for trading in securities...

  2. 75 FR 6241 - Self-Regulatory Organizations; The NASDAQ Stock Market LLC; Notice of Filing of Proposed Rule...

    Science.gov (United States)

    2010-02-08

    ... as a going concern. This requirement, which was adopted in 2003,\\11\\ is duplicative of disclosure... regard to whether it expresses doubt about the ability of the company to continue as a going concern.\\13... reference to the going concern requirement because it will no longer apply. In addition, Nasdaq is proposing...

  3. 77 FR 3539 - Self-Regulatory Organizations; NASDAQ OMX PHLX LLC; Order Approving a Proposed Rule Change...

    Science.gov (United States)

    2012-01-24

    ...) (order approving a joint venture between NYSE and BIDS Holdings L.P.). The Exchange has proposed four... venture with, an Exchange member or an affiliate of an Exchange member in the absence of an effective... with respect to NES, and has demonstrated that NES cannot use any information advantage it may have...

  4. 76 FR 30415 - Self-Regulatory Organizations; NYSE Amex LLC; Notice of Filing of Proposed Rule Change Amending...

    Science.gov (United States)

    2011-05-25

    ..., acquisition, joint venture, spinoff, dissolution, bankruptcy filing or other similar type of event involving... time, place, or information advantage with respect to the proposed proprietary trading activity that... time, place, or information advantage but permits them to more fully utilize booth staff and thereby...

  5. 76 FR 16462 - Self-Regulatory Organizations; NASDAQ OMX BX LLC; Order Approving a Proposed Rule Change Relating...

    Science.gov (United States)

    2011-03-23

    ... a joint venture between NYSE and BIDS Holdings L.P.). The Exchange has proposed four ongoing... responsibility with respect to NES, and has demonstrated that NES cannot use any information advantage it may... members raises potential conflicts of interest, and the potential for unfair competitive advantage.\\26...

  6. Is the Recently Proposed Mars-Sized Perturber at 65–80 AU Ruled Out by the Cassini Ranging Data?

    Energy Technology Data Exchange (ETDEWEB)

    Iorio, Lorenzo, E-mail: lorenzo.iorio@libero.it [Ministero dell' Istruzione, dell' Università e della Ricerca, Rome (Italy)

    2017-10-26

    Recently, the existence of a pointlike pertuber PX with 1 m{sub ♂} ≲ m{sub X} ≲ 2.4 m{sub ⊕} (the symbol “♂” denotes Mars) supposedly moving at 65–80 AU along a moderately inclined orbit has been hypothesized in order to explain certain features of the midplane of the Kuiper Belt Objects (KBOs). We preliminarily selected two possible scenarios for such a PX, and numerically simulated its effect on the Earth-Saturn range ρ(t) by varying some of its orbital parameters over a certain time span; then, we compared our results with some existing actual range residuals. By assuming m{sub X} = 1 m{sub ♂} and a circular orbit, such a putative new member of our Solar System would nominally perturb ρ(t) by a few km over Δt = 12 year (2004 − 2016). However, the Cassini spacecraft accurately measured ρ(t) to the level of σ{sub ρ} ≃ 100 m. Nonetheless, such a scenario should not be considered as necessarily ruled out since the Cassini data were reduced so far without explicitly modeling any PX. Indeed, a NASA JPL team recently demonstrated that an extra-signature as large as 4 km affecting the Kronian range would be almost completely absorbed in fitting incomplete dynamical models, i.e., without PX itself, to such simulated data, thus not showing up in the standard post-fit range residuals. Larger anomalous signatures would instead occur for m{sub X} > 1 m{sub ♂}. Their nominal amplitude could be as large as 50 − 150 km for m{sub X} = 2.4 m{sub ⊕}, thus making less plausible their existence.

  7. Is the Recently Proposed Mars-Sized Perturber at 65–80 AU Ruled Out by the Cassini Ranging Data?

    Directory of Open Access Journals (Sweden)

    Lorenzo Iorio

    2017-10-01

    Full Text Available Recently, the existence of a pointlike pertuber PX with 1 m♂ ≲ mX ≲ 2.4 m⊕ (the symbol “♂” denotes Mars supposedly moving at 65–80 AU along a moderately inclined orbit has been hypothesized in order to explain certain features of the midplane of the Kuiper Belt Objects (KBOs. We preliminarily selected two possible scenarios for such a PX, and numerically simulated its effect on the Earth-Saturn range ρ(t by varying some of its orbital parameters over a certain time span; then, we compared our results with some existing actual range residuals. By assuming mX = 1 m♂ and a circular orbit, such a putative new member of our Solar System would nominally perturb ρ(t by a few km over Δt = 12 year (2004 − 2016. However, the Cassini spacecraft accurately measured ρ(t to the level of σρ ≃ 100 m. Nonetheless, such a scenario should not be considered as necessarily ruled out since the Cassini data were reduced so far without explicitly modeling any PX. Indeed, a NASA JPL team recently demonstrated that an extra-signature as large as 4 km affecting the Kronian range would be almost completely absorbed in fitting incomplete dynamical models, i.e., without PX itself, to such simulated data, thus not showing up in the standard post-fit range residuals. Larger anomalous signatures would instead occur for mX > 1 m♂. Their nominal amplitude could be as large as 50 − 150 km for mX = 2.4 m⊕, thus making less plausible their existence.

  8. 78 FR 21650 - Self-Regulatory Organizations; NYSE Arca, Inc.; Order Granting Approval of Proposed Rule Change...

    Science.gov (United States)

    2013-04-11

    ... efficiency, competition, and capital formation. See 15 U.S.C. 78c(f). II. Description NYSE Euronext intends..., competition, and capital formation. See 15 U.S.C. 78c(f). \\16\\ 15 U.S.C. 78f(b)(5). The proposal would... currently apply to the Exchange. The Exchange would continue as an indirect wholly-owned subsidiary of NYSE...

  9. Research paper no. 18. Trading rules for CO2 emission permits systems. A proposal for ceilings on quantities and prices

    International Nuclear Information System (INIS)

    Criqui, P.; Viguier, L.

    2000-01-01

    Tradable emission permit (TEP) systems for greenhouse gases (GHGs) as they could develop following the Kyoto Protocol - that is if they are limited to Annex B countries and are not bound by exchange regulations) - do not appear to be greatly acceptable today, either to the United States or to the European Union. The problem of the uncertainty related to the cost of reducing emissions is strongly highlighted in the United States: in fact, the approach adopted in the Kyoto Protocol, that of quantitative emissions targets, leaves the question of the reduction programme costs wide open. For the European Union, the unregulated TEP system is hardly acceptable because it would not guarantee that the principle of 'supplementarity' adopted in the Kyoto Protocol, that is, the fact that the purchase of permits should be in addition to action taken within each of the Annex B countries. The section two of this paper is an in-depth economic analysis of the european proposal for ''concrete ceilings''. The alternative proposals, formulated in the United States and relating more to permit price ceilings or''trigger price'', are examined in Section 3. After showing that each of the foregoing proposals could have consequences unacceptable to some or others of the parties to the Protocol, Section 4 offers the proposal of a hybrid formula for regulating the rights market. In fact, the main aim of this paper is to show that the implementation of a 'hybrid solution', consisting of limiting the volume of exchanges while at the same time introducing a TEP price ceiling, could provide a market regulation framework effect allowing the benefits of most of the economic advantages to be enjoyed and also having characteristics acceptable to the various parties from an environmental as well as from an international fairness point of view. (A.L.B.)

  10. Proposed amendments to the Staff Rules & Regulations related to exceptional contract extension beyond the statutory retirement age for members of the personnel appointed by the Council pursuant to Article S II 1.01

    CERN Document Server

    2011-01-01

    Proposed amendments to the Staff Rules & Regulations related to exceptional contract extension beyond the statutory retirement age for members of the personnel appointed by the Council pursuant to Article S II 1.01

  11. Proposed amendments to the Staff Rules and Regulations related to exceptional contract extension beyond the statutory retirement age for members of the personnel appointed by the Council pursuant to article S II 1.01

    CERN Document Server

    2011-01-01

    Proposed amendments to the Staff Rules and Regulations related to exceptional contract extension beyond the statutory retirement age for members of the personnel appointed by the Council pursuant to article S II 1.01

  12. A Proposal for Increasing Student Safety through Suicide Prevention in Schools

    Science.gov (United States)

    Ward, Janice E.; Odegard, Melissa A.

    2011-01-01

    A considerable amount of literature points to the criticality of implementing prevention and intervention strategies to address suicide in the context of schools. The authors address these elements along with a case study to increase student safety in schools.

  13. The Outcomes of an Alcohol Prevention Program on Parents’ Rule Setting and Self-efficacy: A Bi-directional Model

    NARCIS (Netherlands)

    Koning, H.M.; Glatz, T.

    2016-01-01

    Most adolescents have their first encounter with alcohol in early or middle adolescence. Parents’ rule setting about alcohol has been shown to be important to delay the onset and reduce the frequency of adolescents’ alcohol drinking, but less is known about the potential role of parents’ beliefs

  14. Proposed national strategies for the prevention of leading work-related diseases and injuries. Part 1

    Energy Technology Data Exchange (ETDEWEB)

    1986-01-01

    Preliminary strategies developed at the National Symposium on the Prevention of Leading Work Related Diseases and Injuries, held in Atlanta, Georgia on May 1 to 3, 1985 were revised, elaborated, and further developed. Strategies were developed for the prevention of occupational lung diseases, musculoskeletal injuries, occupational cancers, severe occupational traumatic injuries, and occupational cardiovascular diseases. Lung diseases considered included silicosis, asbestosis, lung cancer mesothelioma, coal workers' pneumoconiosis, byssinosis, occupational asthma, hypersensitivity pneumonitis, asphyxiation, irritation, pulmonary edema, brucellosis, psitticosis, anthrax, mycobacterioses, histoplasmosis, aspergillosis, and coccidioidomycosis. Occupational cancers were discussed as they occur in the lung, pleura, peritoneum, bladder, kidneys, blood, nasal cavity, skin, nasal sinuses, and liver.

  15. Proposed Rule and Related Materials for Proposed Finding That Greenhouse Gas Emissions From Aircraft Cause or Contribute to Air Pollution That May Reasonably Be Anticipated To Endanger Public Health and Welfare and Advance Notice of Proposed Rulemaking

    Science.gov (United States)

    FR notice and fact sheet concerning Advance Notice of Proposed Rulemaking that provides information on the process for setting an international CO2 emissions standard for aircraft at the International Civil Aviation Organization (ICAO)

  16. Academic stress in Chinese schools and a proposed preventive intervention program

    OpenAIRE

    Xu Zhao; Robert L. Selman; Helen Haste

    2015-01-01

    While American educators fret about the mediocre educational performance of American students in international contests (e.g. the Program for International Student Assessment) and wonder why the Chinese education system produces such high-achieving students, educators, journalists, and public officials in China want to know what causes and how to prevent the high levels of academic stress that Chinese students, their families, and their school systems experience. So far, much of the blame for...

  17. Blackout control : proposal of a preventive methodology and its implementation in the Portuguese grid

    Energy Technology Data Exchange (ETDEWEB)

    Fernandes, M.M.; Perro, L.L.; Rodrigues, A.C.R. [Rede Electrica Nacional (Portugal)

    2007-07-01

    This paper presented simulation results of the behaviour of the Portuguese electric power transmission grid after the non simultaneous tripping of existing and future natural gas combined-cycle power plants for different load profiles. Of the 62 identified main causes of worldwide major power disturbances, 24 were found to be due to natural events such as fires and storms; 20 were due to failure of primary equipment such as circuit breakers; and, 18 were due to incorrect behaviour of protection systems. A disturbance was classified as a major disturbance if the event had a severity greater then 1 system minute, or if the loss of generation was greater than 10 per cent of peak demand. Seven of these major disturbances have been reported by the Portuguese transmission grid. The tripping of big power plants in Portugal was caused by the loss of multiple grid elements during normal operation of the system. Identifying the main causes of major disturbances offers the possibility of establishing a methodology to prevent major disturbances by simulating the behaviour of the power system under an appropriate set of severe contingencies. This paper described the methodology used to choose the more severe contingencies that should be simulated in the Portuguese transmission grid to help prevent major disturbances. 4 refs., 3 tabs., 5 figs.

  18. A proposal on restart rule of nuclear power plants with piping having local wall thinning subjected to an earthquake. Former part. Aiming at further application

    International Nuclear Information System (INIS)

    Urabe, Yoshio

    2011-01-01

    Restart rule of nuclear power plants (NPPs) with piping having local wall thinning subjected to an earthquake was proposed taking account of local wall thinning, seismic effects and restart of NPPs with applicability of 'Guidelines for NPP Response to an Earthquake (EPRI NP-6695)' in Japan. Japan Earthquake Damage Intensity Scale (JEDIS) and Earthquake Ground Motion Level (EGML) were introduced. JEDIS was classified into four scales obtained from damage level of components and structures of NPPs subjected to an earthquake, while EGML was divided into four levels by safe shutdown earthquake ground motion (So), elastic design earthquake ground motion (Sd) and design earthquake ground motion (Ss). Combination of JEDIS and EGML formulated 4 x 4 matrix and determined detailed conditions of restart of NPPs. As a response to an earthquake, operator walk inspections and evaluation of earthquake ground motion were conducted to know the level of JEDIS. JEDIS level requested respective allowable conditions of restart of NPP, which were scale level dependent and consisted of weighted combination of damage inspection (operator walk inspections, focused inspections/tests and expanded inspections), integrity evaluation and repair/replacement. If JEDIS were assigned greater than 3 with expanded inspections, inspection of piping with local wall thinning, its integrity evaluation and repair/replacement if necessary were requested. Inspection and evaluation of piping with local wall thinning was performed based on JSME or ASME codes. Detailed work flow charts were presented. Carbon steel piping and elbow was chosen for evaluation. (T. Tanaka)

  19. Oncology patients' and their significant others' responses to a proposed cancer prevention/detection program.

    Science.gov (United States)

    Vranicar-Lapka, D; Barbour-Randall, L; Trippon, M; Wild, L D; Coffou, B; Grace-Louthen, C; Hausen, V; Schaeffer, C

    1992-02-01

    We used a needs assessment questionnaire to survey a primarily adult oncology population and their significant others, to gauge their interest in a cancer screening program. The purpose of the study was to determine the feasibility of developing a cancer prevention and detection program for this group of individuals. Although there was overwhelming interest in participating in the program, the subjects held varied opinions about the program's benefits. Differences correlated with personal and familial history of cancer and, in some categories, were quite significant. Additional questionnaire information related to patients' preference in the design of a cancer screening program. The majority preferred the screening examination to be performed by both nurses and physicians. In selecting what should be included in examinations, those surveyed chose testicular cancer and prostate cancer the least number of times. Results of this questionnaire can be used to demonstrate the need for nurses to take an active role in the screening process, especially in patient education.

  20. 32 CFR 324.6 - Procedural rules.

    Science.gov (United States)

    2010-07-01

    ... 32 National Defense 2 2010-07-01 2010-07-01 false Procedural rules. 324.6 Section 324.6 National... DFAS PRIVACY ACT PROGRAM Systems of Records § 324.6 Procedural rules. DFAS procedural rules... first as a proposed rule to allow for public comment and then as a final rule. Procedural rules will be...

  1. Outbreak of resistant Acinetobacter baumannii: measures and proposal for prevention and control

    Directory of Open Access Journals (Sweden)

    Roberta Maia de Castro Romanelli

    Full Text Available Acinetobacter baumannii colonization and infection, frequent in Intensive Care Unit (ICU patients, is commonly associated with high morbimortality. Several outbreaks due to multidrug-resistant (MDR A. baumanii have been reported but few of them in Brazil. This study aimed to identify risk factors associated with colonization and infection by MDR and carbapenem-resistant A. baumannii strains isolated from patients admitted to the adult ICU at HC/UFMG. A case-control study was performed from January 2007 to June 2008. Cases were defined as patients colonized or infected by MDR/carbapenem-resistant A. baumannii, and controls were patients without MDR/carbapenem-resistant A. baumannii isolation, in a 1:2 proportion. For statistical analysis, due to changes in infection control guidelines, infection criteria and the notification process, this study was divided into two periods. During the first period analyzed, from January to December 2007, colonization or infection by MDR/carbapenem-resistant A. baumannii was associated with prior infection, invasive device utilization, prior carbapenem use and clinical severity. In the multivariate analysis, prior infection and mechanical ventilation proved to be statistically significant risk factors. Carbapenem use showed a tendency towards a statistical association. During the second study period, from January to June 2008, variables with a significant association with MDR/carbapenem-resistant A. baumannii colonization/infection were catheter utilization, carbapenem and third-generation cephalosporin use, hepatic transplantation, and clinical severity. In the multivariate analysis, only CVC use showed a statistical difference. Carbapenem and third-generation cephalosporin use displayed a tendency to be risk factors. Risk factors must be focused on infection control and prevention measures considering A. baumanni dissemination.

  2. 75 FR 27272 - Amateur Service Rules

    Science.gov (United States)

    2010-05-14

    ... COMMISSION 47 CFR Part 97 Amateur Service Rules AGENCY: Federal Communications Commission. ACTION: Proposed rule. SUMMARY: This document proposes to amend the amateur radio service rules to facilitate the use of... the amateur service rules by making them conform with other Commission rules, thereby eliminating...

  3. Assisted Protection Headphone Proposal to Prevent Chronic Exposure to Percussion Instruments on Musicians

    Directory of Open Access Journals (Sweden)

    Lorena Parra

    2018-01-01

    Full Text Available The effects of chronic exposure to high sound pressure levels (SPLs are widely studied in the industry environment. However, the way that SPLs affect music students has not been thoroughly examined. In this paper, we study the SPL exposure of batucada students and we propose an assisted protection headphone as a part of e-health system. We measured the SPL reached during a regular percussion class. Pure-tone audiometries were performed to a set of percussion students. The gathered data were statistically analyzed. The assisted protection headphones and their operation are detailed and tested during a regular class. Our results show that 35% of the musicians present with a noise-induced hearing loss, considered as two frequencies with hearing loss of 25 dB or more or one frequency with a hearing loss of 30 dB or more. Our data also shows that those students that do not use any protection have a greater hearing loss. However, the students that use protection headphones are also suffering hearing loss. There might be a problem in the way that musicians are using the protection headphones. Our assisted protection headphones as a part of e-health measures can diminish the negative effects of percussion instruments for musicians.

  4. A Proposed Molecular Mechanism of High-Dose Vitamin D3 Supplementation in Prevention and Treatment of Preeclampsia.

    Science.gov (United States)

    Zabul, Piotr; Wozniak, Michal; Slominski, Andrzej T; Preis, Krzysztof; Gorska, Magdalena; Korozan, Marek; Wieruszewski, Jan; Zmijewski, Michal A; Zabul, Ewa; Tuckey, Robert; Kuban-Jankowska, Alicja; Mickiewicz, Wieslawa; Knap, Narcyz

    2015-06-09

    A randomized prospective clinical study performed on a group of 74 pregnant women (43 presenting with severe preeclampsia) proved that urinary levels of 15-F(2t)-isoprostane were significantly higher in preeclamptic patients relative to the control (3.05 vs. 2.00 ng/mg creatinine). Surprisingly enough, plasma levels of 25-hydroxyvitamin D3 in both study groups were below the clinical reference range with no significant difference between the groups. In vitro study performed on isolated placental mitochondria and placental cell line showed that suicidal self-oxidation of cytochrome P450scc may lead to structural disintegration of heme, potentially contributing to enhancement of oxidative stress phenomena in the course of preeclampsia. As placental cytochrome P450scc pleiotropic activity is implicated in the metabolism of free radical mediated arachidonic acid derivatives as well as multiple Vitamin D3 hydroxylations and progesterone synthesis, we propose that Vitamin D3 might act as a competitive inhibitor of placental cytochrome P450scc preventing the production of lipid peroxides or excess progesterone synthesis, both of which may contribute to the etiopathogenesis of preeclampsia. The proposed molecular mechanism is in accord with the preliminary clinical observations on the surprisingly high efficacy of high-dose Vitamin D3 supplementation in prevention and treatment of preeclampsia.

  5. A Proposed Molecular Mechanism of High-Dose Vitamin D3 Supplementation in Prevention and Treatment of Preeclampsia

    Directory of Open Access Journals (Sweden)

    Piotr Zabul

    2015-06-01

    Full Text Available A randomized prospective clinical study performed on a group of 74 pregnant women (43 presenting with severe preeclampsia proved that urinary levels of 15-F2t-isoprostane were significantly higher in preeclamptic patients relative to the control (3.05 vs. 2.00 ng/mg creatinine. Surprisingly enough, plasma levels of 25-hydroxyvitamin D3 in both study groups were below the clinical reference range with no significant difference between the groups. In vitro study performed on isolated placental mitochondria and placental cell line showed that suicidal self-oxidation of cytochrome P450scc may lead to structural disintegration of heme, potentially contributing to enhancement of oxidative stress phenomena in the course of preeclampsia. As placental cytochrome P450scc pleiotropic activity is implicated in the metabolism of free radical mediated arachidonic acid derivatives as well as multiple Vitamin D3 hydroxylations and progesterone synthesis, we propose that Vitamin D3 might act as a competitive inhibitor of placental cytochrome P450scc preventing the production of lipid peroxides or excess progesterone synthesis, both of which may contribute to the etiopathogenesis of preeclampsia. The proposed molecular mechanism is in accord with the preliminary clinical observations on the surprisingly high efficacy of high-dose Vitamin D3 supplementation in prevention and treatment of preeclampsia.

  6. The New Rule of the Preventing Measures in the Brazilian Criminal Procedure Law: Judicial Subjectivity and Constitutional Criticism.

    Directory of Open Access Journals (Sweden)

    Hamilton da Cunha Iribure Júnior

    2015-12-01

    Full Text Available This approach is summarized in particular in a substantial analysis of some of the main innovations incorporated into the Criminal Procedure Code by Law n. 12.403/11 and its consequences in view of the new constitutional order. The problem is centered in the new procedural devices that add up to a microsystem application specific procedural measures, authorizing of the application of a range of alternatives precautionary measures to procedural prison. One of the start-up propositions of the current Brazilian Constitutional Law is that the State must promote and respect the existence worthy of human beings valuing it both in its individual dimension as a context of social justice. The plea guides a plurality of key elements, which, though heterogeneous, maintain a concatenation each other, justifying the existence of the democratic state. Not only as a Republican foundation, but mainly as a guiding rule creation and interpretation of legal standards, human dignity establishing a new concrete constitutional order making it a fundamental rights application base that, in turn, lining up as the primary core of existence and justification of the state body, his biggest reason. The method employed is the direct, document analysis, inference about the system that currently governs the measures that matter to a lesser restriction on individual freedom by aligning the current thinking of the higher courts in Brazil.

  7. Prevention

    Science.gov (United States)

    ... Error processing SSI file About Heart Disease & Stroke Prevention Heart disease and stroke are an epidemic in ... secondhand smoke. Barriers to Effective Heart Disease & Stroke Prevention Many people with key risk factors for heart ...

  8. Level of information about gynaecological prevention in teenagers at risk from social exclusion, referred by family court rulings to juvenile attendance centres – a pilot study

    Directory of Open Access Journals (Sweden)

    Marcin Bobiński

    2015-09-01

    Full Text Available Introduction and objective. The objective of the study was to present preliminary results of a pilot study concerning the level of knowledge of gynaecological prevention, conducted in teenagers referred by court rulings to a juvenile attendance centre. Materials and method. The instrument was an anonymous survey questionnaire completed by participants in health prevention classes in late 2010 and early 2011. The studied group consisted of teenagers aged 15–17 years (mean age: 15.72 years, median = 16 years, SD = 0.679 who were under probation officers’ supervision in the Zamość region of south-eastern Poland. The sample size was 101 persons – 51 boys (50.50%, 50 girls (49.5%. Results. According to the respondents, the most important reasons for seeing a gynaecologist were: menstrual disorders (70.30%, suspicion of pregnancy (63.37% and pain or burning sensations while urinating (58.42%. The following were regarded as prevalent cancers in women: cancers of the breast (99.01%, cervix (89.1%, and ovaries (62.38%. Over 92% of subjects stated that it was possible to protect oneself from cervical cancer, but only 41.5% of respondents indicated the correct definition of the term ‘cytology’. Statistical analysis focused on differences between genders. A higher self-assessment of mental health was shown in boys. Conclusions. Teenagers of similar background may find it more difficult to gain access to knowledge about health prophylaxis, including gynaecological prevention. Efforts should be intensified in order to ‘equalize health opportunities’ through appropriate preparation of teaching curricula (including health education and philosophy of medicine.

  9. The subgenus names Moraxella subgen. Moraxella and Moraxella subgen. Branhamella and the species names included within these taxa should have been included on the Approved Lists of Bacterial Names and a ruling on the proposal to make changes to Rule 34a. Opinion 83.

    Science.gov (United States)

    2008-07-01

    The Judicial Commission of the International Committee for Systematics of Prokaryotes rules that the following names should have been included on the Approved Lists of Bacterial Names, Moraxella (subgen. Branhamella Bøvre 1979), Moraxella (subgen. Moraxella Lwoff 1939), Moraxella (subgen. Branhamella Bøvre 1979) catarrhalis, Moraxella (subgen. Branhamella Bøvre 1979) caviae, Moraxella (subgen. Branhamella Bøvre 1979) ovis, Moraxella (subgen. Moraxella Lwoff 1939) atlantae, Moraxella (subgen. Moraxella Lwoff 1939) bovis, Moraxella (subgen. Moraxella Lwoff 1939) lacunata, Moraxella (subgen. Moraxella Lwoff 1939) nonliquefaciens, Moraxella (subgen. Moraxella Lwoff 1939) osloensis, Moraxella (subgen. Moraxella Lwoff 1939) phenylpyruvica. Proposals to alter Rule 34a were rejected.

  10. REVIEW OF RULE MODIFICATION IN SPORT

    Directory of Open Access Journals (Sweden)

    Jose L. Arias

    2011-03-01

    Full Text Available The goal of this qualitative review was to analyze the state of the bibliography about rule modification in sport. In the literature reviewed, there are few studies of rule modification and related aspects. Most studies omit mentioning the purpose of the modifications, but they do refer to the goals of their analysis (improving players' performance, attracting spectators and athletes, attending to commercial pressure, adapting the sport to children's needs and interests, preventing injuries. Eighty percent of the studies did not report the outcome of the previous modifications they analyzed. More than half of the studies (60% achieved the proposed goals. Nearly two-thirds (63.83% analyzed the effect of rule modification on game actions occurring during the game or through a test. Most of the studies (91.5% did not consult the participants. Three-fourths of the studies (74.46% examined the effect of rule modification without any knowledge of a previous analysis or without any previous analysis, and 74.47% studied rule modification related to internal logic. Modifications to be introduced in a sport should be analyzed through a reflective process before their final introduction. The following points should be considered: establishing goals, respecting the basic rules without modifying them, becoming familiar with players' and coaches' opinions, determining the effect of the modification on a wide spectrum of variables, elaborating useful proposals for the organizations that are responsible for competitions, using more than one type of data, modifying the internal logic and, preferably, the functional rules, and following some basic stages to consolidate rule modification.

  11. Esophageal lesions following button-battery ingestion in children: Analysis of causes and proposals for preventive measures.

    Science.gov (United States)

    Lahmar, J; Célérier, C; Garabédian, E N; Couloigner, V; Leboulanger, N; Denoyelle, F

    2017-10-17

    To study recent cases of esophageal injury due to button-battery ingestion in children presenting in pediatric ENT emergency departments of the Paris area of France (Île-de-France region), in order to propose appropriate preventive measures. A retrospective descriptive single-center study included all children under 15 years of age, presenting in pediatric ENT emergency departments between January 2008 and April 2014 for button-battery ingestion with esophageal impaction requiring emergency removal. Twenty-two boys and 4 girls, with a median age of 25 months, were included. Twenty-five of the 26 batteries had diameters of 20mm or more. Median esophageal impaction time was 7 hours 30 minutes (range, 2 to 72 hours). The complications rate was 23%. Mean hospital stay cost was €38,751 (range, €5130-119,737). The origin of the battery was known in 23 of the 26 cases: remote control without screw-secured compartment (42.3%), open battery pack (15.4%), children's toy (15.3%), camera (7.7%), watch (1 case) and hearing aid without screw-secured compartment (1 case). Esophageal lesions due to ingestion of button-batteries in children are almost always due to batteries larger than 20mm in diameter, mostly from devices with a poorly protected compartment, or batteries that are not individually packaged. These lesions cause serious complications in a quarter of cases and their management entails high health costs. Legislation requiring screw-secured compartments and individual blisters for batteries could have prevented 69.2% of the ingestions. Copyright © 2017 Elsevier Masson SAS. All rights reserved.

  12. 75 FR 3886 - Amateur Service Rules

    Science.gov (United States)

    2010-01-25

    ... COMMISSION 47 CFR Part 97 Amateur Service Rules AGENCY: Federal Communications Commission. ACTION: Proposed rule. SUMMARY: This document proposes to amend the amateur radio service rules to clarify certain rules and codify existing procedures governing the amateur service vanity call sign system, and to revise...

  13. Prevention

    Science.gov (United States)

    ... Contact Aging & Health A to Z Find a Geriatrics Healthcare Professional Medications & Older Adults Making Your Wishes ... Prevention Hearing Loss Heart Attack High Blood Pressure Nutrition Osteoporosis Shingles Skin Cancer Related News Quitting Smoking, ...

  14. Physical consequences of surgery for breast cancer in the affected upper limb and proposal of preventive physiotherapeutic treatment

    International Nuclear Information System (INIS)

    Masis Tenorio, Ericka; Molina Vargas, Viviana M.

    2008-01-01

    Breast cancer is a malignant growth that begins in breast tissue. The incidence rate in Costa Rica, for 2003, was 40.07 per 100,000 inhabitants (Registro Nacional de Tumores, 2007). The most used treatment for this pathology has been the surgery, has many variations; however, in Costa Rica the modified radical mastectomy and quadrantectomy (conservative surgery) are the most performed. Along with this, other treatments are practiced such as: hormonal therapy, radiation and chemotherapy. The physical consequences of such treatments are: lymphedema, decreased mobility of the shoulder joint on the side of surgery and postoperative pain. The consequences have represented an important change for people that live, because they will have limitations in activities of their daily lives. These can be treated, reduced and even avoided, through a program of physical therapy with techniques and exercises. Costa Rica lacks a prevention program, interdisciplinary and postoperative rehabilitation for people with breast surgery. Therefore, the creation of a proposal of physiotherapeutic intervention based on scientific criteria would be an instrument of great importance. The main objective of this transversal, descriptive and analytic study has been to examine the physical consequences of breast cancer surgery in the affected upper limb. A proposal of physiotherapeutic intervention was designed for the prevention of that physical consequences and possible treatments, from the literature review and valuing people post-breast surgery. In total 27 women were assessed post breast surgery (20 mastectomy and 7 with quadrantectomy), whose time post surgery was located at the range of 1 day -12 months (21 people), more than 12 months (6 people). The selection criteria were: unilateral breast surgery, radical type modified or quadrantectomy; located in the ranges of 35-59 years (19 people) and 60-85 years (8 people); no injuries previous in the upper limb the side of the surgery; with or

  15. 78 FR 39632 - Cotton Board Rules and Regulations: Adjusting Supplemental Assessment on Imports (2013 Amendment)

    Science.gov (United States)

    2013-07-02

    ... Assessment on Imports (2013 Amendment) AGENCY: Agricultural Marketing Service, USDA. ACTION: Proposed rule. SUMMARY: This proposed rule is a companion to the Agricultural Marketing Service's (AMS) direct final rule... 2, 2013 / Proposed Rules#0;#0; [[Page 39632

  16. Prevention

    DEFF Research Database (Denmark)

    Halken, S; Høst, A

    2001-01-01

    , breastfeeding should be encouraged for 4-6 months. In high-risk infants a documented extensively hydrolysed formula is recommended if exclusive breastfeeding is not possible for the first 4 months of life. There is no evidence for preventive dietary intervention neither during pregnancy nor lactation...... populations. These theories remain to be documented in proper, controlled and prospective studies. Breastfeeding and the late introduction of solid foods (>4 months) is associated with a reduced risk of food allergy, atopic dermatitis, and recurrent wheezing and asthma in early childhood. In all infants....... Preventive dietary restrictions after the age of 4-6 months are not scientifically documented....

  17. Testimony of the National Institute for Occupational Safety and Health on the Occupational Safety and Health Administration's proposed rule on hazard communication

    Energy Technology Data Exchange (ETDEWEB)

    Millar, J.D.; Niemeier, R.W.; Reed, L.D.; Johnson, D.L.; Ahlers, H.W.

    1988-12-06

    The testimony was presented in support of earlier information concerning OSHA's final rule to extend coverage of the Hazard Communication Standard to those workers in nonmanufacturing employment as well as those employed in the manufacturing sector. The concept of hazard communication in the workplace was fully supported by NIOSH. It would be desirable to achieve uniformity in the design of and information contained on labels generated by the various industries. One general concern about the OSHA rule was the lack of detailed guidelines on scientific criteria for making the determination of whether a substance is hazardous. The efforts of NIOSH which would be useful as a source of information in determining hazards were again cited. NIOSH agreed with OSHA's view that the extent of risk or size of employer should not be determining factors with regard to a decision as to whether the information must be conveyed. Consumer products used in an industrial setting may carry hazards beyond those anticipated in the home and should also be covered in the label requirements. Material-safety data sheets would provide a base determination of hazard potential and enhance the ability of both employers and workers to identify hazardous chemicals.

  18. [A proposal for the prevention of ethical problems related to drug promotion: a national network for drug information].

    Science.gov (United States)

    Civaner, Murat

    2008-01-01

    The promotional activities of pharmaceutical companies are becoming an increasingly hot topic among healthcare workers and the general public. There are many studies in the literature claiming that drug promotion may lead to ethical problems, irrational use of medication, and increased costs, as well as negative effects on the patient-physician relationship and the medical profession. When considering that healthcare workers generally acquire their knowledge from the pharmaceutical industry, the problems mentioned, which are indeed of paramount importance, and the need for effective and sustainable interventions are clearly revealed. Many kinds of interventions have been recommended by various authorities and studies in order to prevent the kinds of problems mentioned above, including training healthcare workers, publishing professional codes to serve as guidelines about which professional values should be protected and how to cope with different situations in relationship to the pharmaceutical industry, or applying the business ethics codes of the pharmaceutical companies. Studies that assessed the effectiveness of different interventions, however, revealed that educating healthcare workers about marketing methods and state regulations are the only effective interventions. In this article, after defining the problem, a proposed national network for drug information is to decrease the negative effects of drug promotion and to promote the rational choice of medicines is described. According to the World Health Organization, rational use of medicine is the most effective, safe, applicable/suitable, and, lastly, the most cost effective option. A national network that will gather drug information by compiling evidence-based knowledge and taking rational use of medicine measures into account should be established. It should transmit information to all healthcare workers in a fast, equal, up to date, easily accessible, and free way. The network should also support

  19. Rules Extraction with an Immune Algorithm

    Directory of Open Access Journals (Sweden)

    Deqin Yan

    2007-12-01

    Full Text Available In this paper, a method of extracting rules with immune algorithms from information systems is proposed. Designing an immune algorithm is based on a sharing mechanism to extract rules. The principle of sharing and competing resources in the sharing mechanism is consistent with the relationship of sharing and rivalry among rules. In order to extract rules efficiently, a new concept of flexible confidence and rule measurement is introduced. Experiments demonstrate that the proposed method is effective.

  20. Proposed Rule and Related Materials for Control of Emissions of Air Pollution From Nonroad Diesel Engines Control of Air Pollution From Aircraft and Aircraft Engines; Proposed Emission Standards and Test Procedures

    Science.gov (United States)

    EPA is proposing to adopt emission standards and related provisions for aircraft gas turbine engines with rated thrusts greater than 26.7 kilonewtons. These engines are used primarily on commercial passenger and freight aircraft.

  1. Assessment of the environmental impact of the FAA proposed rule making affecting the conditions of transport of radioactive materials on aircraft

    International Nuclear Information System (INIS)

    Hall, R.J.; Hendrickson, P.L.; King, J.C.; McSweeney, T.I.; Shipler, D.B.; Brown, C.L.; Davis, D.K.; Watson, E.C.

    1975-01-01

    Amendments to Federal Aviation Administration (FAA) regulations relating to the transporting of radioactive materials on commercial aircraft are presented. Potential effects of the proposed changes are examined in the environmental impact statement, which is presented in the 10 sections and 5 appendices of this document. (JGB)

  2. Wildlife and the coal waste policy debate: proposed rules for coal waste disposal ignore lessons from 45 years of wildlife poisoning

    Science.gov (United States)

    A. Dennis Lemly; Joseph P. Skorupa

    2012-01-01

    This analysis examines wildlife poisoning from coal combustion waste (CCW) in the context of EPA's proposed policy that would allow continued use of surface impoundments as a disposal method. Data from 21 confirmed damage sites were evaluated, ranging from locations where historic poisoning has led to corrective actions that have greatly improved environmental...

  3. 77 FR 66025 - Program Access Rules

    Science.gov (United States)

    2012-10-31

    ... 76 Program Access Rules; Final Rule and Proposed Rule #0;#0;Federal Register / Vol. 77 , No. 211... 47 CFR Part 76 [MB Docket Nos. 12-68; 07-18; 05-192; 07-29; FCC 12-123] Program Access Rules AGENCY... to extend the prohibition on exclusive contracts involving satellite-delivered, cable-affiliated...

  4. Employee Retirement Income Security Act of 1974; rules and regulations for administration and enforcement; claims procedure--Department of Labor. Notice of proposed rulemaking.

    Science.gov (United States)

    1998-09-09

    This document contains a proposed regulation revising the minimum requirements for benefit claims procedures of employee benefit plans covered by Title I of the Employee Retirement Income Security Act of 1974 (ERISA or the Act). This proposed regulation would establish new standards for the processing of group health disability, pension, and other employee benefit plan claims filed by participants and beneficiaries. In the case of group health plans, as well as certain plans providing disability benefits, the new standards are intended to ensure more timely benefit determinations, improved access to information on which a benefit determination is made, and greater assurance that participants and beneficiaries will be afforded a full and fair review of denied claims. If adopted as final, the proposed regulation would affect participants and beneficiaries of employee benefit plans, plan, fiduciaries, and others who assist in the provision of plan benefits, such as third-party benefits administrators and health service providers or health maintenance organizations that provide benefits to participants and beneficiaries of employee benefit plans.

  5. Proposal for refining business rules for petroleum and natural gas tenure in Alberta 1999 : attachment to Mineral Rights Information Bulletin 99-2

    International Nuclear Information System (INIS)

    1999-01-01

    The position taken by Alberta Energy regarding petroleum and natural gas tenure is discussed. In September 1995, the Petroleum and Natural Gas Tenure Review Advisory Committee was established with representation from the Ministry of Energy and five industry associations. Since then, the Committee has published 10 proposals for industry review. The review resulted in the Mines and Minerals Amendment Act 1997, the Petroleum and Natural Gas Tenure Regulation, the Mines and Minerals Administration Regulation and the Crown Minerals Registration Regulation. The Alberta Department of Energy is committed to introducing further changes where necessary. Some of these changes are described in this proposal. They are: (1) changes to the mission of the the Department of Energy, (2) changes to the mission of the Mineral Operations Division, (3) changes to petroleum and natural gas tenure philosophies, (4) petroleum and natural gas licence administration, (5) petroleum and natural gas tenure regulations, (6) off-location wells, (7) continuations based on the Energy and Utilities Board's (EUB) approved projects, (8) changes to offset notices within the EUB approved projects, (9) serving notices on diagonally cornering spacing units, (10) offset compensation, (11) changes to applications where minister disagrees, (12) trespassing, and (13) water injection, water disposal, waster source and observation wells

  6. Diderot's rule

    OpenAIRE

    Beck, Jonathan

    2009-01-01

    "Like many new products, newly released creative goods such as books, music records and movies are sometimes 'surprise' hits but often flops. Experimental and empirical research suggests that it is hard to predict the demand for a new creative good, and therefore its success, even for industry experts. Rules of thumb on the quantitative properties of demand uncertainty exist for various creative industries - including a rule by Denis Diderot (1763) according to which one out of ten published ...

  7. Peri-implant test is a proposal of a new procedure to prevent peri-implantitis and forensic claims.

    Science.gov (United States)

    Gaudio, R M; Ottria, L; Lauritano, D; Palmieri, A; Cura, F; Tagliabue, A; Tettamanti, L

    2018-01-01

    Implant dentistry has become one of the most successful techniques for oral rehabilitation over the last 20 years. The success rate of implant oral rehabilitation is above 80% while peri-implant disease (PID) is the most important complication of implant dentistry. The main cause of PID is considered bacterial leakage at the implant-abutment connection of a two-piece implant system. Prevention and control of bacterial leakage at the implant-abutment connection is mandatory for reducing inflammation process around implants neck and achieving bone stability. Since bacteria leakage at implant-abutment connection level is the main cause of PID, a microbiological test should be important to identify bacteria that cause PID. According with the conclusion of workshop of the European Federation on Periodontology, a test that detects the most frequent bacterial species involved in the onset of PID (Actinobacillus actinomycetecomitans, Porphyromonas gengivalis, Tannnerella forsythia, Treponema denticola) should be used in clinical practice. In fact, PID progression depends on the typology, quantity and composition of bacterial flora in peri-implant pockets, so controlling PID onset and progression, is a keystone for preventing implant failures and consequently forensic conflicts. The effort to prevent PID and consequently assurance or forensic conflicts have become one of the main focal points of all dental professionals. Behind these efforts lie, above all, ethical but also economic reasons, as well as a desire to prevent PID, improving implant care quality and increasing the legal security of health care professionals themselves. Since the legal decisions in our society influence how we practice dentistry, especially in the fast-evolving field of implant dentistry, using diagnostic tools that will allow dentists to demonstrate that they have acted correctly in accordance with the knowledge of modern medicine, it is of great importance to defend themselves in the case of

  8. Ranking Cases with Classification Rules

    Science.gov (United States)

    Zhang, Jianping; Bala, Jerzy W.; Hadjarian, Ali; Han, Brent

    Many real-world machine learning applications require a ranking of cases, in addition to their classification. While classification rules are not a good representation for ranking, the human comprehensibility aspect of rules makes them an attractive option for many ranking problems where such model transparency is desired. There have been numerous studies on ranking with decision trees, but not many on ranking with decision rules. Although rules are similar to decision trees in many respects, there are important differences between them when used for ranking. In this chapter, we propose a framework for ranking with rules. The framework extends and substantially improves on the reported methods for ranking with decision trees. It introduces three types of rule-based ranking methods: post analysis of rules, hybrid methods, and multiple rule set analysis. We also study the impact of rule learning bias on the ranking performance. While traditional measures used for ranking performance evaluation tend to focus on the entire rank ordered list, the aim of many ranking applications is to optimize the performance on only a small portion of the top ranked cases. Accordingly, we propose a simple method for measuring the performance of a classification or ranking algorithm that focuses on these top ranked cases. Empirical studies have been conducted to evaluate some of the proposed methods.

  9. Public comments on the proposed 10 CFR Part 51 rule for renewal of nuclear power plant operating licenses and supporting documents: Review of concerns and NRC staff response. Volume 1

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-05-01

    This report documents the Nuclear Regulatory Commission (NRC) staff review of public comments provided in response to the NRC`s proposed amendments to 10 Code of Federal Regulations (CFR) Part 51, which establish new requirements for the environmental review of applications for the renewal of operating licenses of nuclear power plants. The public comments include those submitted in writing, as well as those provided at public meetings that were held with other Federal agencies, State agencies, nuclear industry representatives, public interest groups, and the general public. This report also contains the NRC staff response to the various concerns raised, and highlights the changes made to the final rule and the supporting documents in response to these concerns.

  10. 75 FR 12803 - Fingerprint Submission Requirements Rule

    Science.gov (United States)

    2010-03-17

    ... NATIONAL CRIME PREVENTION AND PRIVACY COMPACT COUNCIL Fingerprint Submission Requirements Rule... Fingerprint Submission Requirements Rule, title 28 Code of Federal Regulations (CFR), part 901. FOR FURTHER... the Fingerprint Submission Requirements Rule (28 CFR, part 901) when health or safety of vulnerable...

  11. Development of a Reinforcement Learning-based Evolutionary Fuzzy Rule-Based System for diabetes diagnosis.

    Science.gov (United States)

    Mansourypoor, Fatemeh; Asadi, Shahrokh

    2017-12-01

    The early diagnosis of disease is critical to preventing the occurrence of severe complications. Diabetes is a serious health problem. A variety of methods have been developed for diagnosing diabetes. The majority of these methods have been developed in a black-box manner, which cannot be used to explain the inference and diagnosis procedure. Therefore, it is essential to develop methods with high accuracy and interpretability. In this study, a Reinforcement Learning-based Evolutionary Fuzzy Rule-Based System (RLEFRBS) is developed for diabetes diagnosis. The proposed model involves the building of a Rule Base (RB) and rule optimization. The initial RB is constructed using numerical data without initial rules; after learning the rules, redundant rules are eliminated based on the confidence measure. Next, redundant conditions in the antecedent parts are pruned to yield simpler rules with higher interpretability. Finally, an appropriate subset of the rules is selected using a Genetic Algorithm (GA), and the RB is constructed. Evolutionary tuning of the membership functions and weight adjusting using Reinforcement Learning (RL) are used to improve the performance of RLEFRBS. Moreover, to deal with uncovered instances, it makes use of an efficient rule stretching method. The performance of RLEFRBS was examined using two common datasets: Pima Indian Diabetes (PID) and BioSat Diabetes Dataset (BDD). The experimental results show that the proposed model provides a more compact, interpretable and accurate RB that can be considered to be a promising alternative for diagnosis of diabetes. Copyright © 2017 Elsevier Ltd. All rights reserved.

  12. Rule, Britannia

    DEFF Research Database (Denmark)

    Christensen, Jørgen Riber

    2011-01-01

    . The climax of the masque was “Rule, Britannia!” This song advocated a strong navy as a guard against the absolutist European powers with their lack of civil liberties. Furthermore, a strong navy made a standing army superfluous, and so an army could not be deployed as a repressive force of the state. Later...

  13. A Brief Review of Intimate Partner Violence in the United States: Nature, Correlates, and Proposed Preventative Measures

    Directory of Open Access Journals (Sweden)

    Pamela C. Regan

    2015-12-01

    Full Text Available Aggression and violence are themes which characterize a significant proportion of many close romantic relationships. Both women and men may find themselves caught in a web of intimate terror – controlled, manipulated, and hurt by a coercive and violent partner. In this brief review article, we summarize existing literature on the form of intimate partner violence known as coercive controlling violence (CCV, domestic abuse, or intimate terrorism. We begin by discussing the nature and consequences of CCV relationships. Personal or individual (e.g., biological sex, age, immigrant status, socioeconomic status, attitudes and beliefs, mental health and psychopathology, relational or interpersonal (e.g., relationship type, relationship satisfaction, and environmental (e.g., economic strain, social isolation risk factors associated with the occurrence of domestic abuse are identified. Finally, potential preventative measures at the individual, interpersonal, and sociocultural level that may serve to reduce the likelihood of this pernicious interpersonal phenomenon are considered.

  14. Proposal for a limit value reduction scenario for road vehicles compatible with the German national traffic noise prevention. Package II

    Energy Technology Data Exchange (ETDEWEB)

    Steven, Heinz [Data Analysis and Consultancy, Heinsberg (Germany)

    2012-03-15

    With COM(2011) 856 final from 09.12.2011 the EU Commission launched a proposal for a regulation of the European Parliament and of the Council on the sound level of motor vehicles. This proposal is related to motor vehicles having at least four wheels. Objective and aim are described as follows: ''The objective of the proposal is to ensure a high level of health and environmental protection and to safeguard the Internal Market for motor vehicles as regards their sound level. The proposal aims at reducing environmental noise by introducing a new test method for measuring noise emissions, by lowering the noise limit values, by including additional sound emission provisions in the type-approval procedure...'' (see paragraph 1 of the explanatory memorandum). Under the bullet point ''- new limit values'' of paragraph 1 of the explanatory memorandum the following statements are listed: ''On the basis of the results of the monitoring data an impact assessment has been prepared with different policy options for the noise test method and corresponding limit values. According to the most preferable option the limit values for light and medium size vehicles will be lowered in two steps of each 2 dB(A) and for heavy vehicles in a first step of 1 and a second step of 2 dB(A). This will result in a reduction of the noise impact of about 3 dB(A) for free flowing traffic and up to 4 dB(A) for intermittent traffic. The reduction of the number of highly annoyed people will be 25 %. The cost-benefit ratio for this measure is estimated to be around 20 times in favour of the noise reduction compared to no action taken.'' The forecast for the reduction of the noise impact in real traffic is far too optimistic. It is highly unlikely that the reduction of limit values by 3 to 4 dB will lead to a reduction of the noise impact in real traffic by the same amount without any deterioration factor. Own calculations with the TRANECAM

  15. Amendments to general regulations of the Food and Drug Administration. Direct final rule.

    Science.gov (United States)

    2010-11-30

    The Food and Drug Administration (FDA) is amending certain of its general regulations to include tobacco products, where appropriate, in light of FDA's authority to regulate these products under the Family Smoking Prevention and Tobacco Control Act (Tobacco Control Act). With these amendments, tobacco products will be subject to the same general requirements that apply to other FDA-regulated products. Elsewhere in this issue of the Federal Register, we are publishing a companion proposed rule under FDA's usual procedures for notice and comment to provide a procedural framework to finalize the rule in the event we receive significant adverse comment and withdraw this direct final rule.

  16. Proposal of reference stress for a surface flaw on a cylindrical component from a review-with-comparison of the local metal loss assessment rule between API 579-1 and the p-M diagram method

    International Nuclear Information System (INIS)

    Oyamada, Kenji; Konosu, Shinji; Ohno, Takashi

    2011-01-01

    The Remaining Strength Factor (RSF) approach in Part 5 of API 579-1/ASME FFS-1 is an assessment method for a cylindrical component with a local metal loss based on surface correction factors. Also, reference stress solutions that are applied in the Failure Assessment Diagram (FAD) method for a cylindrical component with a crack-like flaw are provided in Annex D using surface correction factors. In the recently-developed p-M diagram method, the reference stress solution for local metal loss evaluation in a cylindrical component is derived using bulging factors, which are similar but not identical to the surface correction factors used in API 579-1/ASME FFS-1. This paper describes the results of a comparative study among the RSF approach, reference stress solutions for the FAD method, and the p-M diagram method, in terms of plastic collapse evaluation of a cylindrical component. These results were compared with the FEA and experimental results to confirm how these estimated stresses could be validated. This study also involves recommended reference stress solutions for a cylindrical component with a crack-like flaw or a local metal loss, which should be adopted as fitness-for-service rules, and a discussion on the influence of the design margin of the construction code on allowable flaw depth. - Highlights: → We compared local metal loss assessment rule between API 579-1 and the p-M method. → Experiments and FEA verified the p-M estimate stress state around a flaw accurate. → API 579-1 for local metal loss may underestimate stress state for certain conditions. → Existing reference stresses for crack-like flaws may underestimate stress state too. → We propose the reference stress for a surface flaw subjected to pressure and moment.

  17. Comprehensive suppression of all apoptosis-induced proliferation pathways as a proposed approach to colorectal cancer prevention and therapy.

    Directory of Open Access Journals (Sweden)

    Michael Bordonaro

    Full Text Available Mutations in the WNT/beta-catenin pathway are present in the majority of all sporadic colorectal cancers (CRCs, and histone deacetylase inhibitors induce apoptosis in CRC cells with such mutations. This apoptosis is counteracted by (1 the signaling heterogeneity of CRC cell populations, and (2 the survival pathways induced by mitogens secreted from apoptotic cells. The phenomena of signaling heterogeneity and apoptosis-induced survival constitute the immediate mechanisms of resistance to histone deacetylase inhibitors, and probably other chemotherapeutic agents. We explored the strategy of augmenting CRC cell death by inhibiting all survival pathways induced by the pro-apoptotic agent LBH589, a histone deacetylase inhibitor: AKT, JAK/STAT, and ERK signaling. The apoptosis-enhancing ability of a cocktail of synthetic inhibitors of proliferation was compared to the effects of the natural product propolis. We utilized colorectal adenoma, drug-sensitive and drug-resistant colorectal carcinoma cells to evaluate the apoptotic potential of the combination treatments. The results suggest that an effective approach to CRC combination therapy is to combine apoptosis-inducing drugs (e.g., histone deacetylase inhibitors, such as LBH589 with agents that suppress all compensatory survival pathways induced during apoptosis (such as the cocktail of inhibitors of apoptosis-associated proliferation. The same paradigm can be applied to a CRC prevention approach, as the apoptotic effect of butyrate, a diet-derived histone deacetylase inhibitor, is augmented by other dietary agents that modulate survival pathways (e.g., propolis and coffee extract. Thus, dietary supplements composed by fermentable fiber, propolis, and coffee extract may effectively counteract neoplastic growth in the colon.

  18. Risk estimation and value-of-information analysis for three proposed genetic screening programs for chronic beryllium disease prevention

    Energy Technology Data Exchange (ETDEWEB)

    Bartell, S.M.; Ponce, R.A.; Takaro, T.K.; Zerbe, R.O.; Omenn, G.S.; Faustman, E.M.

    2000-02-01

    Genetic differences (polymorphisms) among members of a population are thought to influence susceptibility to various environmental exposures. In practice, however, this information is rarely incorporated into quantitative risk assessment and risk management. The authors describe an analytic framework for predicting the risk reduction and value-of-information (VOI) resulting from specific risk management applications of genetic biomarkers, and they apply the framework to the example of occupational chronic beryllium disease (CBD), an immune-mediated pulmonary granulomatous disease. One described Human Leukocyte Antigen gene variant, HLA-DP{beta}1*0201, contains a substitution of glutamate for lysine at position 69 that appears to have high sensitivity ({approximately}94%) but low specificity ({approximately}70%) with respect to CBD among individuals occupationally exposed to respirable beryllium. The expected postintervention CBD prevalence rates for using the genetic variant (1) as a required job placement screen, (2) as a medical screen for semiannual in place of annual lymphocyte proliferation testing, or (3) as a voluntary job placement screen are 0.08%, 0.8%, and 0.6%, respectively, in a hypothetical cohort with 1% baseline CBD prevalence. VOI analysis is used to examine the reduction in total social cost, calculated as the net value of disease reduction and financial expenditures, expected for proposed CBD intervention programs based on the genetic susceptibility test. For the example cohort the expected net VOI per beryllium worker for genetically based testing and intervention is $13,000, $1,800, and $5,100, respectively, based on a health valuation of $1.45 million per CBD case avoided. VOI results for alternative CBD valuations are also presented. Despite large parameter uncertainty, probabilistic analysis predicts generally positive utility for each of the three evaluated programs when avoidance of a CBD case is valued at $1 million or higher. Although

  19. The CCCTB Rules on Leaving a Group

    NARCIS (Netherlands)

    van de Streek, J.

    2012-01-01

    The consolidation system proposed in the draft of the CCCTB Directive puts relationships between Member States on edge. This is clearly apparent in the rules that apply when a company leaves a group. In this article the leaving rules are examined. Although the leaving rules are claimed to be

  20. 78 FR 64425 - Current Good Manufacturing Practice and Hazard Analysis and Risk-Based Preventive Controls for...

    Science.gov (United States)

    2013-10-29

    ... Risk- Based Preventive Controls for Food for Animals; Public Meeting on Proposed Rule AGENCY: Food and... requirements for current good manufacturing practice and hazard analysis and risk-based preventive controls for... regulations requiring preventive controls for human food and animal food, set standards for produce safety...

  1. A proposed approach to monitor private-sector policies and practices related to food environments, obesity and non-communicable disease prevention.

    Science.gov (United States)

    Sacks, G; Swinburn, B; Kraak, V; Downs, S; Walker, C; Barquera, S; Friel, S; Hawkes, C; Kelly, B; Kumanyika, S; L'Abbé, M; Lee, A; Lobstein, T; Ma, J; Macmullan, J; Mohan, S; Monteiro, C; Neal, B; Rayner, M; Sanders, D; Snowdon, W; Vandevijvere, S

    2013-10-01

    Private-sector organizations play a critical role in shaping the food environments of individuals and populations. However, there is currently very limited independent monitoring of private-sector actions related to food environments. This paper reviews previous efforts to monitor the private sector in this area, and outlines a proposed approach to monitor private-sector policies and practices related to food environments, and their influence on obesity and non-communicable disease (NCD) prevention. A step-wise approach to data collection is recommended, in which the first ('minimal') step is the collation of publicly available food and nutrition-related policies of selected private-sector organizations. The second ('expanded') step assesses the nutritional composition of each organization's products, their promotions to children, their labelling practices, and the accessibility, availability and affordability of their products. The third ('optimal') step includes data on other commercial activities that may influence food environments, such as political lobbying and corporate philanthropy. The proposed approach will be further developed and piloted in countries of varying size and income levels. There is potential for this approach to enable national and international benchmarking of private-sector policies and practices, and to inform efforts to hold the private sector to account for their role in obesity and NCD prevention. © 2013 The Authors. Obesity Reviews published by John Wiley & Sons Ltd on behalf of the International Association for the Study of Obesity.

  2. Using association rules mining to explore pattern of Chinese medicinal formulae (prescription) in treating and preventing breast cancer recurrence and metastasis.

    Science.gov (United States)

    He, Yanhua; Zheng, Xiao; Sit, Cindy; Loo, Wings T Y; Wang, ZhiYu; Xie, Ting; Jia, Bo; Ye, Qiaobo; Tsui, Kamchuen; Chow, Louis W C; Chen, Jianping

    2012-09-19

    Chinese herbal medicine is increasingly widely used as a complementary approach for control of breast cancer recurrence and metastasis. In this paper, we examined the implicit prescription patterns behind the Chinese medicinal formulae, so as to explore the Chinese medicinal compatibility patterns or rules in the treatment or control of breast cancer recurrence and metastasis. This study was based on the herbs recorded in Pharmacopoeia of the People's Republic of China, and the literature sources from Chinese Journal Net and China Master Dissertations Full-text Database (1990 - 2010) to analyze the compatibility rule of the prescription. Each Chinese herb was listed according to the selected medicinal formulae and the added information was organized to establish a database. The frequency and the association rules of the prescription patterns were analyzed using the SPSS Clenmentine Data Mining System. An initial statistical analysis was carried out to categorize the herbs according to their medicinal types and dosage, natures, flavors, channel tropism, and functions. Based on the categorization, the frequencies of occurrence were computed. The main prescriptive features from the selected formulae of the mining data are: (1) warm or cold herbs in the Five Properties category; sweet or bitter herbs in the Five Flavors category and with affinity to the liver meridian are the most frequently prescribed in the 96 medicinal formulae; (2) herbs with tonifying and replenishing, blood-activating and stasis-resolving, spleen-strengthening and dampness-resolving or heat-clearing and detoxicating functions that are frequently prescribed; (3) herbs with blood-tonifying, yin-tonifying, spleen-strengthening and dampness-resolving, heat-clearing and detoxicating, and blood-activating with stasis-resolving functions that are interrelated and prescribed in combination with qi-tonifying herbs. The results indicate that there is a close relationship between recurrence and metastasis

  3. Level of information about gynaecological prevention in teenagers at risk from social exclusion, referred by family court rulings to juvenile attendance centres – a pilot study

    Directory of Open Access Journals (Sweden)

    Marcin Bobiński

    2015-09-01

    Teenagers of similar background may find it more difficult to gain access to knowledge about health prophylaxis, including gynaecological prevention. Efforts should be intensified in order to ‘equalize health opportunities’ through appropriate preparation of teaching curricula (including health education and philosophy of medicine.

  4. Collaboration rules.

    Science.gov (United States)

    Evans, Philip; Wolf, Bob

    2005-01-01

    Corporate leaders seeking to boost growth, learning, and innovation may find the answer in a surprising place: the Linux open-source software community. Linux is developed by an essentially volunteer, self-organizing community of thousands of programmers. Most leaders would sell their grandmothers for workforces that collaborate as efficiently, frictionlessly, and creatively as the self-styled Linux hackers. But Linux is software, and software is hardly a model for mainstream business. The authors have, nonetheless, found surprising parallels between the anarchistic, caffeinated, hirsute world of Linux hackers and the disciplined, tea-sipping, clean-cut world of Toyota engineering. Specifically, Toyota and Linux operate by rules that blend the self-organizing advantages of markets with the low transaction costs of hierarchies. In place of markets' cash and contracts and hierarchies' authority are rules about how individuals and groups work together (with rigorous discipline); how they communicate (widely and with granularity); and how leaders guide them toward a common goal (through example). Those rules, augmented by simple communication technologies and a lack of legal barriers to sharing information, create rich common knowledge, the ability to organize teams modularly, extraordinary motivation, and high levels of trust, which radically lowers transaction costs. Low transaction costs, in turn, make it profitable for organizations to perform more and smaller transactions--and so increase the pace and flexibility typical of high-performance organizations. Once the system achieves critical mass, it feeds on itself. The larger the system, the more broadly shared the knowledge, language, and work style. The greater individuals' reputational capital, the louder the applause and the stronger the motivation. The success of Linux is evidence of the power of that virtuous circle. Toyota's success is evidence that it is also powerful in conventional companies.

  5. Description logic rules

    CERN Document Server

    Krötzsch, M

    2010-01-01

    Ontological modelling today is applied in many areas of science and technology,including the Semantic Web. The W3C standard OWL defines one of the most important ontology languages based on the semantics of description logics. An alternative is to use rule languages in knowledge modelling, as proposed in the W3C's RIF standard. So far, it has often been unclear how to combine both technologies without sacrificing essential computational properties. This book explains this problem and presents new solutions that have recently been proposed. Extensive introductory chapters provide the necessary

  6. Reflections on the Goldwater Rule.

    Science.gov (United States)

    Appelbaum, Paul S

    2017-06-01

    The APA's Goldwater Rule, precluding psychiatrists from rendering opinions to the media about public figures whom they have not examined, has often engendered controversy. Here, I consider the justifications for the rule, how well they stand up to criticism, and the extent, if any, to which modifications might be called for. Although embarrassment to the profession is often cited as the basis for the Rule, it reflects more substantive concerns, including the risk of harm to living persons and discouraging persons in need of treatment from seeking psychiatric attention. The most potent criticisms of the Rule are that it discourages public education about mental illness and its effects and precludes legitimate scholarly endeavors by psychiatrists studying foreign leaders, historical figures, and others. However, there are many ways of providing education about mental illness without violating the Rule, and read properly, it should not prevent legitimate historical investigation, though some clarification of the Rule on this point might be helpful. Even psychiatrists who seek to aid policymakers in dealing with international or domestic threats should not find that the Rule interferes with their efforts. On balance, the Goldwater Rule continues to be an important underpinning of ethical behavior by psychiatrists. © 2017 American Academy of Psychiatry and the Law.

  7. Hybrid Tree-rule Firewall for High Speed Data Transmission

    OpenAIRE

    Chomsiri, Thawatchai.; He, Xiangjian.; Nanda, Priyadarsi.; Tan, Zhiyuan.

    2016-01-01

    Traditional firewalls employ listed rules in both configuration and process phases to regulate network traffic. However, configuring a firewall with listed rules may create rule conflicts, and slows down the firewall. To overcome this problem, we have proposed a Tree-rule firewall in our previous study. Although the Tree-rule firewall guarantees no conflicts within its rule set and operates faster than traditional firewalls, keeping track of the state of network connections using hashing func...

  8. Proposal of guideline for bonding to prevention of hydrogen embrittlement at Ta/Zr bond interface. Hydrogen embrittlement in SUS304ULC/Ta/Zr explosive bonded joint

    International Nuclear Information System (INIS)

    Saida, Kazuyoshi; Fujimoto, Tetsuya; Nishimoto, Kazutoshi

    2010-01-01

    The occurrence condition of hydrogen embrittlement cracking at Ta/Zr bond interface was investigated with respect to the hydrogen content and applied stress in order to propose a guideline for the explosive bonding procedure to prevention of hydrogen embrittlement. Hydrogen charging test was conducted for SUS304ULC/Ta/Zr explosive bonded joints applied the different flexural strains. A hydrogen embrittlement crack occurred in the Zr substrate at Ta/Zr bond interface after hydrogen charging, and it was initiated at shorter charging times when the augmented strain was increased. The occurrence condition of hydrogen embrittlement cracking at Ta/Zr bond interface was shifted to lower stress and hydrogen content with an increase in the amount of explosive during bonding. It was suggested that hydrogen embrittlement in Ta/Zr explosive bonded joint could be inhibited by reducing the initial hydrogen content in Ta substrate less than approx. 5 ppm. (author)

  9. Performance analysis and implementation of proposed mechanism for detection and prevention of security attacks in routing protocols of vehicular ad-hoc network (VANET

    Directory of Open Access Journals (Sweden)

    Parul Tyagi

    2017-07-01

    Full Text Available Next-generation communication networks have become widely popular as ad-hoc networks, broadly categorized as the mobile nodes based on mobile ad-hoc networks (MANET and the vehicular nodes based vehicular ad-hoc networks (VANET. VANET is aimed at maintaining safety to vehicle drivers by begin autonomous communication with the nearby vehicles. Each vehicle in the ad-hoc network performs as an intelligent mobile node characterized by high mobility and formation of dynamic networks. The ad-hoc networks are decentralized dynamic networks that need efficient and secure communication requirements due to the vehicles being persistently in motion. These networks are more susceptible to various attacks like Warm Hole attacks, denial of service attacks and Black Hole Attacks. The paper is a novel attempt to examine and investigate the security features of the routing protocols in VANET, applicability of AODV (Ad hoc On Demand protocol to detect and tackle a particular category of network attacks, known as the Black Hole Attacks. A new algorithm is proposed to enhance the security mechanism of AODV protocol and to introduce a mechanism to detect Black Hole Attacks and to prevent the network from such attacks in which source node stores all route replies in a look up table. This table stores the sequences of all route reply, arranged in ascending order using PUSH and POP operations. The priority is calculated based on sequence number and discard the RREP having presumably very high destination sequence number. The result show that proposed algorithm for detection and prevention of Black Hole Attack increases security in Intelligent Transportation System (ITS and reduces the effect of malicious node in the VANET. NCTUNs simulator is used in this research work.

  10. CBT in the prevention of psychosis and other severe mental disorders in patients with an at risk mental state: A review and proposed next steps.

    Science.gov (United States)

    van der Gaag, Mark; van den Berg, David; Ising, Helga

    2017-08-28

    Patients with an 'At risk mental state' (ARMS) for developing psychosis can be treated successfully with CBT to postpone and prevent the transition to a first psychotic episode. A characteristic of individuals that meet ARMS criteria is that they are still open for multiple explanations for extraordinary experiences. CBT aims to normalize extraordinary experiences with education and to prevent delusional explanations. The treatment is not only effective, but also cost-saving in averting psychosis as well as in reducing disability adjusted life years at 18- and 48-month follow-up. Profiling within the ARMS group results in a personalized treatment. The screening and early treatment for ARMS fulfills all the criteria of the World Health Organization and is ready to be routine screening and treatment in mental health care. At the same time, ARMS patients are complex patients with multi-morbid disorders. Especially childhood trauma is associated to ARMS status, together with co-morbid PTSD, depression, substance abuse and anxiety disorders. Psychotic symptoms appear to be severity markers in other non-psychotic disorders. Preventing psychosis in ARMS patients should be broadened to also address other disorders and aim to reduce chronicity of psychopathology and improve social functioning in general. Several mechanisms play a part in psychopathology in ARMS patients such as stress sensitivity as a result of adverse experiences, dopamine sensitivity that is associated with salience and aggravates several cognitive biases, dissociation mediating between trauma and hallucinations, and low self-esteem and self-stigma. New avenues to treat the complexity of ARMS patients will be proposed. Copyright © 2017 Elsevier B.V. All rights reserved.

  11. Comparison of Heuristics for Inhibitory Rule Optimization

    KAUST Repository

    Alsolami, Fawaz

    2014-09-13

    Knowledge representation and extraction are very important tasks in data mining. In this work, we proposed a variety of rule-based greedy algorithms that able to obtain knowledge contained in a given dataset as a series of inhibitory rules containing an expression “attribute ≠ value” on the right-hand side. The main goal of this paper is to determine based on rule characteristics, rule length and coverage, whether the proposed rule heuristics are statistically significantly different or not; if so, we aim to identify the best performing rule heuristics for minimization of rule length and maximization of rule coverage. Friedman test with Nemenyi post-hoc are used to compare the greedy algorithms statistically against each other for length and coverage. The experiments are carried out on real datasets from UCI Machine Learning Repository. For leading heuristics, the constructed rules are compared with optimal ones obtained based on dynamic programming approach. The results seem to be promising for the best heuristics: the average relative difference between length (coverage) of constructed and optimal rules is at most 2.27% (7%, respectively). Furthermore, the quality of classifiers based on sets of inhibitory rules constructed by the considered heuristics are compared against each other, and the results show that the three best heuristics from the point of view classification accuracy coincides with the three well-performed heuristics from the point of view of rule length minimization.

  12. AIDS Prevention: Views on the Administration's Budget Proposals. Briefing Report to the Chairman, Subcommittee on Labor, Health and Human Services, Education and Related Agencies, Committee on Appropriations, United States Senate.

    Science.gov (United States)

    General Accounting Office, Washington, DC. Div. of Human Resources.

    The General Accounting Office (GAO) conducted a study in response to Senator Lawton Chiles' request that the GAO explore the adequacy of the funding levels proposed for the Department of Health and Human Services' Public Health Service and the appropriateness of priorities reflected in the administration's proposed budget for prevention of…

  13. Hybrid tree-rule firewall for high speed data transmission

    NARCIS (Netherlands)

    Chomsiri, Thawatchai; He, Xiangjian; Nanda, Priyadarsi; Tan, Zhiyuan

    2017-01-01

    Traditional firewalls employ listed rules in both configuration and process phases to regulate network traffic. However, configuring a firewall with listed rules may create rule conflicts, and slows down the firewall. To overcome this problem, we have proposed a Tree-rule firewall in our previous

  14. 75 FR 14259 - Transportation Conformity Rule PM2.5

    Science.gov (United States)

    2010-03-24

    ... Protection Agency 40 CFR Part 93 Transportation Conformity Rule PM2.5 and PM10 Amendments; Final Rule #0;#0...; ] ENVIRONMENTAL PROTECTION AGENCY 40 CFR Part 93 RIN 2060-AP29 Transportation Conformity Rule PM 2.5 and PM 10... amending the transportation conformity rule to finalize provisions that were proposed on May 15, 2009...

  15. Ruling by Record

    DEFF Research Database (Denmark)

    Nuijten, Monique; Lorenzo, David

    2009-01-01

    This contribution looks at land property relations in a peasant community in the central highlands of Peru. Rather than using a rights-based approach, the authors propose a `practice force field approach' for their analysis of property relations under communal land tenure regimes. Their study...... combines qualitative ethnographic case studies with quantitative analysis of data on land distribution. In contrast to rights-based approaches, this perspective understands the legal discourses that people draw upon to explain property relations as `justifying rule talk' rather than the reflection...

  16. 77 FR 20127 - Swap Dealer and Major Swap Participant Recordkeeping, Reporting, and Duties Rules; Futures...

    Science.gov (United States)

    2012-04-03

    ... Commission Merchant and Introducing Broker Conflicts of Interest Rules; and Chief Compliance Officer Rules... Recordkeeping, Reporting, and Duties Rules; Futures Commission Merchant and Introducing Broker Conflicts of... of trading to prevent violations of applicable position limits; diligent supervision; business...

  17. Risk Management Plan (RMP) Rule Overview

    Science.gov (United States)

    As required by Section 112(r) of the Clean Air Act Amendments, this rule contains regulations and guidance for chemical accident prevention at facilities that use extremely hazardous substances, and aids in emergency preparedness and response.

  18. Symptom-based screening tool in ruling out active tuberculosis among HIV-infected patients eligible for isoniazid preventive therapy in Tanzania.

    Science.gov (United States)

    Shayo, Grace A; Minja, Lilian T; Egwaga, Said; Bakari, Muhammad; Mugusi, Ferdinand M

    2014-06-01

    We assessed the usefulness of the National TB and Leprosy Control Program (NTLP) symptom-based tuberculosis (TB) screening tool in identifying HIV-infected patients eligible for isoniazid preventive therapy in Muhimbili National Hospital, Dar es Salaam Tanzania. Descriptive cross-sectional study. Data collected included socio-demographic and clinical data. Chest X-ray, sputum for acid-fast bacilli (AFB) microscopy, mycobacterial culture, CD4 + count and complete blood count were performed. Patients were considered not having active TB if they presented with no symptom in the screening tool, which comprised these symptoms: cough, fever and excessive night sweats for ≥2 weeks; weight loss of ≥3 kg in 4 weeks and haemoptysis of any duration. The reference standard was a negative culture for Mycobacterium tuberculosis. We enroled 373 patients, of whom 72.1% were females. Active pulmonary TB was found in 4.1% (14/338) of the participants as defined by a positive culture. The sensitivity and specificity of the NTLP screening tool were 71.4% (10/14) and 75.9% (246/324), respectively. False-negative rate was 28.6% (4/10). Cough, fever for ≥2 weeks and weight loss were independent predictors of NTLP-defined TB. Cough ≥2 weeks predicted TB when a positive culture was used to define TB. The screening tool had fairly good sensitivity and specificity for TB screening; however, there is a possibility that about 29% of the screened population will be given IPT while they are supposed to receive a full course of TB treatment. © 2014 John Wiley & Sons Ltd.

  19. 77 FR 19799 - Pipeline Safety: Pipeline Damage Prevention Programs

    Science.gov (United States)

    2012-04-02

    ... rates translate to increased public and worker safety and decreased repair and outage costs for pipeline... April 2, 2012 Part III Department of Transportation Pipeline and Hazardous Materials Safety Administration 49 CFR Parts 196 and 198 Pipeline Safety: Pipeline Damage Prevention Programs; Proposed Rule #0;#0...

  20. 76 FR 6247 - National Standards To Prevent, Detect, and Respond to Prison Rape

    Science.gov (United States)

    2011-02-03

    ... Standards To Prevent, Detect, and Respond to Prison Rape; Proposed Rule #0;#0;Federal Register / Vol. 76, No..., Detect, and Respond to Prison Rape AGENCY: Department of Justice. ACTION: Notice of proposed rulemaking... abuse in confinement settings that were prepared by the National Prison Rape Elimination Commission...

  1. Intuitionistic Rules : Admissible Rules of Intermediate Logics

    NARCIS (Netherlands)

    Goudsmit, J.P.

    2015-01-01

    In this thesis, we investigate the admissible rules of intermediate logics. On the one hand, one can characterize the admissibility of rules in certain logic, and on the other hand, one can characterize logics through their admissible rules. We take both approaches, and reach new results in both

  2. Rough set based decision rule generation to find behavioural ...

    Indian Academy of Sciences (India)

    In this study, we proposed rough set based decision rule generation framework to find reduct and to generate decision rules for predicting the Decision class. We conducted experiments over data of Portuguese Banking institution. From the proposed method, the dimensionality of data is reduced and decision rules are ...

  3. Guide to the collision avoidance rules

    CERN Document Server

    Cockcroft, A N

    2004-01-01

    A Guide to the Collision Avoidance Rules is the essential reference to the safe operation of all vessels at sea. Published continuously since 1965, this respected and expert guide is the classic text for all who need to, practically and legally, understand and comply with the Rules. This sixth edition incorporates all of the amendments to the International Regulations for Preventing Collisions at Sea which came into force in November 2003.The books sets out all of the Rules with clear explanation of their meaning, and gives detailed examples of how the rules have been used in practice

  4. 76 FR 7782 - Defense Federal Acquisition Regulation Supplement; Rules of the Armed Services Board of Contract...

    Science.gov (United States)

    2011-02-11

    ... Acquisition Regulation Supplement; Rules of the Armed Services Board of Contract Appeals AGENCY: Defense... proposed rule to update the Rules of the Armed Services Board of Contract Appeals (ASBCA). The proposed... proposes to amend DFARS Appendix A, Armed Services Board of Contract Appeals, Part 2--Rules, to update...

  5. Total Coliform Rule Distribution System Advisory Committee (TCRDSAC) Document

    Science.gov (United States)

    This document provide information about the TCRDSAC, including its charter, processes and recommendations. The Agency used the Advisory Committee recommendations to develop proposed and final rules that revised the Total Coliform Rule.

  6. 77 FR 23176 - Revisions to Procedural Rules

    Science.gov (United States)

    2012-04-18

    ... Procedural Rules AGENCY: Postal Regulatory Commission. ACTION: Advance notice of proposed rulemaking. SUMMARY... opinion conforms to the appropriate statutory requirements. 39 U.S.C. 3661(c). B. Current Procedural Regulations The Commission's procedural rules implementing the requirements of section 3661 can be found in 39...

  7. What Is a Rule of Grammar?

    Science.gov (United States)

    Lardiere, Donna

    2014-01-01

    This article offers commentary on the Multiple Grammars (MG) language acquisition theory proposed by Luiz Amaral and Tom Roeper in this issue. It argues that more precise definitions are needed for the terms "rule," "simple," and "productive." Topics discussed include Amaral and Roeper's verb second (V2) rule,…

  8. Discovering Sentinel Rules for Business Intelligence

    DEFF Research Database (Denmark)

    Middelfart, Morten; Pedersen, Torben Bach

    2009-01-01

    This paper proposes the concept of sentinel rules for multi-dimensional data that warns users when measure data concerning the external environment changes. For instance, a surge in negative blogging about a company could trigger a sentinel rule warning that revenue will decrease within two month...

  9. Unexpected rules using a conceptual distance based on fuzzy ontology

    Directory of Open Access Journals (Sweden)

    Mohamed Said Hamani

    2014-01-01

    Full Text Available One of the major drawbacks of data mining methods is that they generate a notably large number of rules that are often obvious or useless or, occasionally, out of the user’s interest. To address such drawbacks, we propose in this paper an approach that detects a set of unexpected rules in a discovered association rule set. Generally speaking, the proposed approach investigates the discovered association rules using the user’s domain knowledge, which is represented by a fuzzy domain ontology. Next, we rank the discovered rules according to the conceptual distances of the rules.

  10. Understanding the Residential Wood Heater Rules

    Science.gov (United States)

    Information on the components of the current wood heater new source performance standards (NSPS) and proposed updates to the NSPS including which types of heaters are covered under the rules and the benefits.

  11. 76 FR 69788 - Self-Regulatory Organizations; New York Stock Exchange LLC; Notice of Filing of Rule Change...

    Science.gov (United States)

    2011-11-09

    ... Proposed Rule Change The Exchange proposes a one-year pilot program that would add new Rule 107C to.... Purpose The Exchange is proposing a one-year pilot program that would add new NYSE Rule 107C to establish...-Regulatory Organizations; New York Stock Exchange LLC; Notice of Filing of Rule Change Proposing a One-Year...

  12. The effect of a sports chiropractic manual therapy intervention on the prevention of back pain, hamstring and lower limb injuries in semi-elite Australian Rules footballers: a randomized controlled trial

    Directory of Open Access Journals (Sweden)

    Pollard Henry

    2010-04-01

    Full Text Available Abstract Background Hamstring injuries are the most common injury in Australian Rules football. It was the aims to investigate whether a sports chiropractic manual therapy intervention protocol provided in addition to the current best practice management could prevent the occurrence of and weeks missed due to hamstring and other lower-limb injuries at the semi-elite level of Australian football. Methods Sixty male subjects were assessed for eligibility with 59 meeting entry requirements and randomly allocated to an intervention (n = 29 or control group (n = 30, being matched for age and hamstring injury history. Twenty-eight intervention and 29 control group participants completed the trial. Both groups received the current best practice medical and sports science management, which acted as the control. Additionally, the intervention group received a sports chiropractic intervention. Treatment for the intervention group was individually determined and could involve manipulation/mobilization and/or soft tissue therapies to the spine and extremity. Minimum scheduling was: 1 treatment per week for 6 weeks, 1 treatment per fortnight for 3 months, 1 treatment per month for the remainder of the season (3 months. The main outcome measure was an injury surveillance with a missed match injury definition. Results After 24 matches there was no statistical significant difference between the groups for the incidence of hamstring injury (OR:0.116, 95% CI:0.013-1.019, p = 0.051 and primary non-contact knee injury (OR:0.116, 95% CI:0.013-1.019, p = 0.051. The difference for primary lower-limb muscle strains was significant (OR:0.097, 95%CI:0.011-0.839, p = 0.025. There was no significant difference for weeks missed due to hamstring injury (4 v14, χ2:1.12, p = 0.29 and lower-limb muscle strains (4 v 21, χ2:2.66, p = 0.10. A significant difference in weeks missed due to non-contact knee injury was noted (1 v 24, χ2:6.70, p = 0.01. Conclusions This study

  13. The effect of a sports chiropractic manual therapy intervention on the prevention of back pain, hamstring and lower limb injuries in semi-elite Australian Rules footballers: a randomized controlled trial.

    Science.gov (United States)

    Hoskins, Wayne; Pollard, Henry

    2010-04-08

    Hamstring injuries are the most common injury in Australian Rules football. It was the aims to investigate whether a sports chiropractic manual therapy intervention protocol provided in addition to the current best practice management could prevent the occurrence of and weeks missed due to hamstring and other lower-limb injuries at the semi-elite level of Australian football. Sixty male subjects were assessed for eligibility with 59 meeting entry requirements and randomly allocated to an intervention (n = 29) or control group (n = 30), being matched for age and hamstring injury history. Twenty-eight intervention and 29 control group participants completed the trial. Both groups received the current best practice medical and sports science management, which acted as the control. Additionally, the intervention group received a sports chiropractic intervention. Treatment for the intervention group was individually determined and could involve manipulation/mobilization and/or soft tissue therapies to the spine and extremity. Minimum scheduling was: 1 treatment per week for 6 weeks, 1 treatment per fortnight for 3 months, 1 treatment per month for the remainder of the season (3 months). The main outcome measure was an injury surveillance with a missed match injury definition. After 24 matches there was no statistical significant difference between the groups for the incidence of hamstring injury (OR:0.116, 95% CI:0.013-1.019, p = 0.051) and primary non-contact knee injury (OR:0.116, 95% CI:0.013-1.019, p = 0.051). The difference for primary lower-limb muscle strains was significant (OR:0.097, 95%CI:0.011-0.839, p = 0.025). There was no significant difference for weeks missed due to hamstring injury (4 v 14, chi2:1.12, p = 0.29) and lower-limb muscle strains (4 v 21, chi2:2.66, p = 0.10). A significant difference in weeks missed due to non-contact knee injury was noted (1 v 24, chi2:6.70, p = 0.01). This study demonstrated a trend towards lower limb injury prevention

  14. Phonological reduplication in sign language: rules rule

    Directory of Open Access Journals (Sweden)

    Iris eBerent

    2014-06-01

    Full Text Available Productivity—the hallmark of linguistic competence—is typically attributed to algebraic rules that support broad generalizations. Past research on spoken language has documented such generalizations in both adults and infants. But whether algebraic rules form part of the linguistic competence of signers remains unknown. To address this question, here we gauge the generalization afforded by American Sign Language (ASL. As a case study, we examine reduplication (X→XX—a rule that, inter alia, generates ASL nouns from verbs. If signers encode this rule, then they should freely extend it to novel syllables, including ones with features that are unattested in ASL. And since reduplicated disyllables are preferred in ASL, such rule should favor novel reduplicated signs. Novel reduplicated signs should thus be preferred to nonreduplicative controls (in rating, and consequently, such stimuli should also be harder to classify as nonsigns (in the lexical decision task. The results of four experiments support this prediction. These findings suggest that the phonological knowledge of signers includes powerful algebraic rules. The convergence between these conclusions and previous evidence for phonological rules in spoken language suggests that the architecture of the phonological mind is partly amodal.

  15. The gold standard as a rule

    OpenAIRE

    Michael D. Bordo; Finn E. Kydland

    1992-01-01

    In this paper, we show that the monetary rule followed by a number of key countries, especially England and to a lesser extent the U. S., before 1914 represented a commitment technology preventing the monetary authorities from changing planned future policy. The experiences of these major countries suggest that the gold standard was intended as a contingent rule. By that, we mean, that the authorities could temporarily abandon the fixed price of gold during a wartime emergency on the understa...

  16. 77 FR 24301 - Revision of the Commission's Program Access Rules

    Science.gov (United States)

    2012-04-23

    ...-delivered, cable-affiliated programming; and (ii) potential revisions to our program access rules to better... Revision of the Commission's Program Access Rules; Proposed Rule #0;#0;Federal Register / Vol. 77 , No. 78... Part 76 [MB Docket Nos. 12-68, 07-18, and 05-192; FCC 12-30] Revision of the Commission's Program...

  17. SUR UNE REGLE DE "CACAPHONIE" (ON A RULE OF "CACAPHONY").

    Science.gov (United States)

    GROSS, MAURICE

    A TRANSFORMATIONAL ANALYSIS OF MODERN FRENCH GRAMMAR IS SIMILAR TO THE "RULE OF CACAPHONY" PROPOSED BY PORT-ROYAL GRAMMARIANS TO AVOID BAD PRONUNCIATION. BY MEANS OF CERTAIN REWRITE RULES, THE CORRECT USAGE OF THE PARTITIVE (DE) CAN BE TAUGHT AND EXPLAINED MORE SIMPLY THAN WAS POSSIBLE USING THE TRADITIONAL METHOD. THE RULE OF CACAPHONY…

  18. 18 CFR 385.605 - Arbitration (Rule 605).

    Science.gov (United States)

    2010-04-01

    ... 18 Conservation of Power and Water Resources 1 2010-04-01 2010-04-01 false Arbitration (Rule 605... Stipulations § 385.605 Arbitration (Rule 605). (a) Authorization of arbitration. (1) The participants may at any time submit a written proposal to use binding arbitration under the provisions of Rule 605 to...

  19. 78 FR 10573 - Used Motor Vehicle Trade Regulation Rule

    Science.gov (United States)

    2013-02-14

    ... FEDERAL TRADE COMMISSION 16 CFR Part 455 Used Motor Vehicle Trade Regulation Rule AGENCY: Federal Trade Commission. ACTION: Extension of time period within which to submit comments. SUMMARY: On December... (``NPR'') concerning proposed changes to the Used Motor Vehicle Trade Regulation Rule (``Used Car Rule...

  20. On the performance of different control charting rules

    NARCIS (Netherlands)

    Riaz, M.; Mehmood, R.; Does, R.J.M.M.

    2011-01-01

    In the literature a number of control charting rules are proposed to decide whether a process is in control or out of control. Some issues with these rules will be highlighted in this article. By redefining and listing a set of rules we will evaluate their performance on the X-bar, R, S and S2