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Sample records for prepare fertilizer prescriptions

  1. Sperm preparation for fertilization

    NARCIS (Netherlands)

    Gadella, B.M.

    2014-01-01

    Description This book contains 19 chapters that discuss theoretical and applied andrology for domestic, zoo and wild animals. Topics include semen and its constituents; sperm production and harvest; determinants of sperm morphology; sperm preparation for fertilization; practical aspects of semen cry

  2. Preparing for a Hurricane: Prescription Medications

    Centers for Disease Control (CDC) Podcasts

    2006-08-10

    What you should do to protect yourself and your family from a hurricane. As you evacuate, remember to take your prescription medicines with you.  Created: 8/10/2006 by Emergency Communications System.   Date Released: 7/17/2008.

  3. Structural and impedance characterization of ceramics prepared from NPK fertilizer

    Directory of Open Access Journals (Sweden)

    Diouma Kobor

    2015-06-01

    Full Text Available One of the main objectives of this work was to study the possibilities of valorising the phosphates through the development of a conductive ceramics using NPK fertilizer as a precursor. Phosphorus based powders were synthesized using solid state technique from NPK fertilizer, lithium chloride and iron chloride at different temperatures up to 900 °C and ceramic samples were prepared by the powder pressing and sintering at 1100 °C. XRD spectra of the calcined powders show various sharp peaks indicating a relatively high degree of crystallinity and presence of different crystalline phases, such as: phosphorus based crystalline compounds (AlPO4 and LiFePO4, ferrite (Fe3O4 and DyFeO3, CaSO4 and K3DyCl6. The prepared phosphorus based ceramics showed very interesting electrical and dielectric properties. Thus, in the future the obtained ceramics could find application in electronic or energy storage devices. However, further investigations are necessary to understand the exact chemical composition and structural characteristics of this material, to better understand the origin of the obtained electrical and dielectric behaviour.

  4. Electrochemical process for the preparation of nitrogen fertilizers

    Science.gov (United States)

    Aulich, Ted R.; Olson, Edwin S.; Jiang, Junhua

    2013-03-19

    The present invention provides methods and apparatus for the preparation of nitrogen fertilizers including ammonium nitrate, urea, urea-ammonium nitrate, and/or ammonia utilizing a source of carbon, a source of nitrogen, and/or a source of hydrogen. Implementing an electrolyte serving as ionic charge carrier, (1) ammonium nitrate is produced via the reduction of a nitrogen source at the cathode and the oxidation of a nitrogen source at the anode; (2) urea or its isomers are produced via the simultaneous cathodic reduction of a carbon source and a nitrogen source; (3) ammonia is produced via the reduction of nitrogen source at the cathode and the oxidation of a hydrogen source at the anode; and (4) urea-ammonium nitrate is produced via the simultaneous cathodic reduction of a carbon source and a nitrogen source, and anodic oxidation of a nitrogen source. The electrolyte can be solid.

  5. Electrochemical process for the preparation of nitrogen fertilizers

    Energy Technology Data Exchange (ETDEWEB)

    Aulich, Ted R [Grand Forks, ND; Olson, Edwin S [Grand Forks, ND; Jiang, Junhua [Grand Forks, ND

    2012-04-10

    The present invention provides methods and apparatus for the preparation of nitrogen fertilizers including ammonium nitrate, urea, urea-ammonium nitrate, and/or ammonia, at low temperature and pressure, preferably at ambient temperature and pressure, utilizing a source of carbon, a source of nitrogen, and/or a source of hydrogen or hydrogen equivalent. Implementing an electrolyte serving as ionic charge carrier, (1) ammonium nitrate is produced via the reduction of a nitrogen source at the cathode and the oxidation of a nitrogen source at the anode; (2) urea or its isomers are produced via the simultaneous cathodic reduction of a carbon source and a nitrogen source; (3) ammonia is produced via the reduction of nitrogen source at the cathode and the oxidation of a hydrogen source or a hydrogen equivalent such as carbon monoxide or a mixture of carbon monoxide and hydrogen at the anode; and (4) urea-ammonium nitrate is produced via the simultaneous cathodic reduction of a carbon source and a nitrogen source, and anodic oxidation of a nitrogen source. The electrolyte can be aqueous, non-aqueous, or solid.

  6. Development of pharmaceutical heroin preparations for medical co-prescription to opioid dependent patients.

    Science.gov (United States)

    Klous, Marjolein G; Van den Brink, Wim; Van Ree, Jan M; Beijnen, Jos H

    2005-12-12

    Presently, there is a considerable interest in heroin-assisted treatment: co-prescription of heroin to certain subgroups of chronic, treatment-resistant, opioid dependent patients. In 2002, nine countries had planned (Australia, Belgium, Canada, France, Spain) or ongoing (Germany, The Netherlands, Switzerland, United Kingdom) clinical trials on this subject. These trials (and the routine heroin-assisted treatment programs that might result) will need pharmaceutical heroin (diacetylmorphine) to prescribe to the patients. Research into the development of pharmaceutical forms of heroin for prescription to addicts can benefit from the large amount of knowledge that already exists regarding this substance. Therefore, in this paper we review the physicochemical and pharmaceutical properties of diacetylmorphine and the clinically investigated routes of administration, as well as routes of administration utilised on the street in the context of developing pharmaceutical heroin formulations for prescription to addicts. Patient acceptability of the formulation is essential, because heroin-assisted treatment is aimed at treatment-resistant addicts, who often have to be encouraged to participate (or to maintain participation) in a treatment program. This means that the most suitable products would have pharmacokinetic profiles mimicking that of diacetylmorphine for injection, with rapid peak concentrations of diacetylmorphine and 6-acetylmorphine, ensuring the 'rush effect' and the sustained presence of morphine(-6-glucuronide) creating the prolonged euphoria. Diacetylmorphine for inhalation after volatilisation (via 'chasing the dragon') seems to be a suitable candidate, while intranasal and oral diacetylmorphine are currently thought to be unsuitable. However, oral and intranasal delivery systems might be improved and become suitable for use by heroin dependent patients.

  7. Preparation and characterization of controlled-release fertilizers coated with marine polysaccharide derivatives

    Science.gov (United States)

    Wang, Jing; Liu, Song; Qin, Yukun; Chen, Xiaolin; Xing, Rong'e.; Yu, Huahua; Li, Kecheng; Li, Pengcheng

    2017-09-01

    Encapsulation of water-soluble nitrogen fertilizers by membranes can be used to control the release of nutrients to maximize the fertilization effect and reduce environmental pollution. In this research, we formulated a new double-coated controlled-release fertilizer (CRF) by using food-grade microcrystalline wax (MW) and marine polysaccharide derivatives (calcium alginate and chitosan-glutaraldehyde copolymer). The pellets of water-soluble nitrogen fertilizer were coated with the marine polysaccharide derivatives and MW. A convenient and eco-friendly method was used to prepare the CRF. Scanning electron microscopy (SEM) and Fourier transform infrared spectroscopy (FTIR) were used to characterize the morphology and composition of the products. The nitrogen-release properties were determined in water using UV-Vis spectrophotometry. The controlled-release properties of the fertilizer were improved dramatically after coating with MW and the marine polysaccharide derivatives. The results show that the double-coated CRFs can release nitrogen in a controlled manner, have excellent controlled-release features, and meet the European Standard for CRFs.

  8. Preparation and characterization of controlled-release fertilizers coated with marine polysaccharide derivatives

    Science.gov (United States)

    Wang, Jing; Liu, Song; Qin, Yukun; Chen, Xiaolin; Xing, Rong'e.; Yu, Huahua; Li, Kecheng; Li, Pengcheng

    2016-10-01

    Encapsulation of water-soluble nitrogen fertilizers by membranes can be used to control the release of nutrients to maximize the fertilization effect and reduce environmental pollution. In this research, we formulated a new double-coated controlled-release fertilizer (CRF) by using food-grade microcrystalline wax (MW) and marine polysaccharide derivatives (calcium alginate and chitosan-glutaraldehyde copolymer). The pellets of water-soluble nitrogen fertilizer were coated with the marine polysaccharide derivatives and MW. A convenient and eco-friendly method was used to prepare the CRF. Scanning electron microscopy (SEM) and Fourier transform infrared spectroscopy (FTIR) were used to characterize the morphology and composition of the products. The nitrogen-release properties were determined in water using UV-Vis spectrophotometry. The controlled-release properties of the fertilizer were improved dramatically after coating with MW and the marine polysaccharide derivatives. The results show that the double-coated CRFs can release nitrogen in a controlled manner, have excellent controlled-release features, and meet the European Standard for CRFs.

  9. Intercalation of urea into kaolinite for preparation of controlled release fertilizer

    OpenAIRE

    Mahdavi Fariba; Abdul Rashid Suraya; Khanif Yusop Mohd

    2014-01-01

    In this study urea was intercalated between layers of kaolinite by dry grinding technique to be used for preparing controlled release fertilizer. X-ray powder diffraction (XRPD) patterns confirmed the intercalation of urea into kaolinite by the significant expansion of the basal spacing of kaolinite layers from 0.710 nm to 1.090 nm. Fourier transform infrared spectroscopy (FT-IR) also confirmed the hydrogen bonding between urea and kaolinite. Based on CHNS ...

  10. Intercalation of urea into kaolinite for preparation of controlled release fertilizer

    OpenAIRE

    Mahdavi Fariba; Abdul Rashid Suraya; Khanif Yusop Mohd

    2014-01-01

    In this study urea was intercalated between layers of kaolinite by dry grinding technique to be used for preparing controlled release fertilizer. X-ray powder diffraction (XRPD) patterns confirmed the intercalation of urea into kaolinite by the significant expansion of the basal spacing of kaolinite layers from 0.710 nm to 1.090 nm. Fourier transform infrared spectroscopy (FT-IR) also confirmed the hydrogen bonding between urea and kaolinite. Based on CHNS ...

  11. Intercalation of urea into kaolinite for preparation of controlled release fertilizer

    Directory of Open Access Journals (Sweden)

    Mahdavi Fariba

    2014-01-01

    Full Text Available In this study urea was intercalated between layers of kaolinite by dry grinding technique to be used for preparing controlled release fertilizer. X-ray powder diffraction (XRPD patterns confirmed the intercalation of urea into kaolinite by the significant expansion of the basal spacing of kaolinite layers from 0.710 nm to 1.090 nm. Fourier transform infrared spectroscopy (FT-IR also confirmed the hydrogen bonding between urea and kaolinite. Based on CHNS elemental analysis, 20% (wt. urea was intercalated between kaolinite layers. The urea-intercalated kaolinite was mixed with hydroxypropyl methylcellulose (HPMC binder and was granulated to prepare the nitrogen-based controlled release fertilizer. To study the nitrogen release behavior of granules, ultraviolet/visible (UV-Vis spectroscopy was used through the diacetyl monoxime (DAM colorimetric method. The result of UV-Vis spectroscopy showed that intercalation of urea into kaolinite decreased the nitrogen release from 25.50 to 13.66 % after 24 hours and from 98.15 to 70.01% after 30 days incubation in water. According to the results, the prepared controlled release fertilizer (CRF behaved according to the standard for CRFs.

  12. EFFECT OF BULL AND SPERM PREPARATION METHOD ON IN VITRO FERTILIZATION OF BUFFALO OOCYTES

    Directory of Open Access Journals (Sweden)

    H. JAMIL, H. A. SAMAD, Z. I. QURESHI, N. REHMAN AND L. A. LODHI

    2007-01-01

    Full Text Available The present study was designed to compare fertilization rates following oocyte exposure to spermatozoa from different buffalo bulls, using three sperm preparation methods i.e. percoll density gradient, swim-up (modified Ca2 free Tyrode’s medium and TALP medium and sodium citrate washing prior to co-incubation with oocytes. Buffalo oocytes were aspirated from ovarian follicles within 1.5 to 2 hours after slaughter. They were matured in TCM-199 supplemented with 20% oestrus buffalo serum drops under mineral oil in CO2 incubator at 39C for 24 hours. Matured oocytes were transferred to the fertilization droplets and inseminated with 1x106 capacitated sperms prepared by different experimental methods. Data collected on recovered sperm motility immediately after treatment and 24 hours after incubation (at 37C and cleavage rate of co-incubated oocytes were subjected to statistical analysis. The percentage of motile spermatozoa was significantly higher (P<0.05 in semen samples prepared by swim-up method in Ca2 free Tyrode’s medium compared to other experimental techniques. Bull wise comparison showed significantly higher (P<0.05 motility in bull B1 (50.50 ± 5.92%, followed by bull B2 (46.46 ± 5.99% and B3 (45.96 ± 5.79%. Fertilization rate was also significantly (P<0.05 higher for spermatozoa prepared by Swim-up method in Ca2 free Tyrode’s medium (63.75 ± 2.81%, followed by sodium citrate (26.70 ± 5.08%, swim-up TALP (29.14 ± 3.74% and Percoll gradient density (23.89 ± 3.88%. Fertilization rate was significantly higher (P<0.05 in oocytes inseminated with semen from bull B1 (43.43 ± 8.59%, followed by B2 (33.38 ± 9.95% and B3 (30.80 ± 9.56%. The results of present study indicate that bulls and sperm preparation methods differ in their contribution to in vitro fertilization rate. Further studies are suggested to ascertain the factors responsible for such specific effects.

  13. Preparation and Testing of Cementing and Coating Nano-Subnanocomposites of Slow/Controlled-Release Fertilizer

    Institute of Scientific and Technical Information of China (English)

    LIU Xiu-mei; FENG Zhao-bin; ZHANG Fu-dao; ZHANG Shu-qing; HE Xu-sheng

    2006-01-01

    To select the cementing and coating materials of slow/controlled-release fertilizer, the natural kaoline and abandoned foam plastics were used to prepare nano-subnanocomposites through the methods of organic material intercalation, semiemulsification, and cut at high velocity techniques. Besides, two kinds of nano-subnanocomposites were tested in this study using several instruments, including the scanning electron microscope (SEM), the X-ray diffraction (XRD), the infrared ray spectrum (IR), and the laser granularity. The main results were as follows: 1) The organic material was intercalated in the layers of kaoline clays, and the natural kaoline exfoliated into nanometer-sized layers. The organic agent and clays formed nanocomposites through hydrogen bond combination. 2) The SEM pictures of polystyrenestarch nano-subnanocomposites showed that many pores and rugas were present on the surface of film at sizes ranging from 10 to 20 nm. These nano-subnanocomposites were used as the cementing and coating materials of slow/controlledrelease fertilizer.

  14. Biological Processes that Prepare Mammalian Spermatozoa to Interact with an Egg and Fertilize It

    Directory of Open Access Journals (Sweden)

    Daulat R. P. Tulsiani

    2012-01-01

    Full Text Available In the mouse and other mammals studied, including man, ejaculated spermatozoa cannot immediately fertilize an egg. They require a certain period of residence in the female genital tract to become functionally competent cells. As spermatozoa traverse through the female genital tract, they undergo multiple biochemical and physiological changes collectively referred to as capacitation. Only capacitated spermatozoa interact with the extracellular egg coat, the zona pellucida. The tight irreversible binding of the opposite gametes triggers a Ca2+-dependent signal transduction cascade. The net result is the fusion of the sperm plasma membrane and the underlying outer acrosomal membrane at multiple sites that causes the release of acrosomal contents at the site of sperm-egg adhesion. The hydrolytic action of the acrosomal enzymes released, along with the hyperactivated beat pattern of the bound spermatozoon, is important factor that directs the sperm to penetrate the egg coat and fertilize the egg. The sperm capacitation and the induction of the acrosomal reaction are Ca2+-dependent signaling events that have been of wide interest to reproductive biologists for over half a century. In this paper, we intend to discuss data from this and other laboratories that highlight the biological processes which prepare spermatozoa to interact with an egg and fertilize it.

  15. Inpatients’ medical prescription errors

    Directory of Open Access Journals (Sweden)

    Aline Melo Santos Silva

    2009-09-01

    Full Text Available Objective: To identify and quantify the most frequent prescription errors in inpatients’ medical prescriptions. Methods: A survey of prescription errors was performed in the inpatients’ medical prescriptions, from July 2008 to May 2009 for eight hours a day. Rresults: At total of 3,931 prescriptions was analyzed and 362 (9.2% prescription errors were found, which involved the healthcare team as a whole. Among the 16 types of errors detected in prescription, the most frequent occurrences were lack of information, such as dose (66 cases, 18.2% and administration route (26 cases, 7.2%; 45 cases (12.4% of wrong transcriptions to the information system; 30 cases (8.3% of duplicate drugs; doses higher than recommended (24 events, 6.6% and 29 cases (8.0% of prescriptions with indication but not specifying allergy. Cconclusion: Medication errors are a reality at hospitals. All healthcare professionals are responsible for the identification and prevention of these errors, each one in his/her own area. The pharmacist is an essential professional in the drug therapy process. All hospital organizations need a pharmacist team responsible for medical prescription analyses before preparation, dispensation and administration of drugs to inpatients. This study showed that the pharmacist improves the inpatient’s safety and success of prescribed therapy.

  16. Controlled-release fertilizer prepared using a biodegradable aliphatic copolyester of poly(butylene succinate) and dimerized fatty acid.

    Science.gov (United States)

    Lubkowski, Krzysztof; Smorowska, Aleksandra; Grzmil, Barbara; Kozłowska, Agnieszka

    2015-03-18

    The preparation and characterization of a controlled-release multicomponent (NPK) fertilizer with the coating layer consisting of a biodegradable copolymer of poly(butylene succinate) and a butylene ester of dilinoleic acid (PBS/DLA) is reported. The morphology and structure of the resulting polymer-coated materials and the thickness of the covering layers were examined using X-ray diffraction and scanning electron microscopy coupled with energy dispersive X-ray analysis. The mechanical properties of these materials were determined with a strength-testing machine. Nutrient release was measured in water using spectrophotometry, potentiometry, and conductivity methods. The results of the nutrient release experiments from these polymer-coated materials were compared with the requirements for controlled-release fertilizers. A conceptual model is presented describing the mechanism of nutrient release from the materials prepared in this study. This model is based on the concentrations of mineral components inside the water-penetrated fertilizer granules, the diffusion properties of the nutrients in water, and a diffusion coefficient through the polymer layer. The experimental kinetic data on nutrient release were interpreted using the sigmoidal model equation developed in this study.

  17. Preparation and properties of a coated slow-release and water-retention biuret phosphoramide fertilizer with superabsorbent.

    Science.gov (United States)

    Jin, Shuping; Yue, Guoren; Feng, Lei; Han, Yuqi; Yu, Xinghai; Zhang, Zenghu

    2011-01-12

    In this investigation, a novel water-insoluble slow-release fertilizer, biuret polyphosphoramide (BPAM), was formulated and synthesized from urea, phosphoric acid (H(3)PO(4)), and ferric oxide (Fe(2)O(3)). The structure of BPAM was characterized by Fourier transform infrared (FTIR) spectroscopy. Subsequently, a coated slow-release BPAM fertilizer with superabsorbent was prepared by ionic cross-linked carboxymethylchitosan (the core), acrylic acid, acrylamide, and active carbon (the coating). The variable influences on the water absorbency were investigated and optimized. Component analysis results showed that the coated slow-release BPAM contained 5.66% nitrogen and 11.7% phosphorus. The property of water retention, the behavior of slow release of phosphorus, and the capacity of adsorption of cations were evaluated, and the results revealed that the product not only had good slow-release property and excellent water retention capacity but also higher adsorption capacities of cations in saline soil.

  18. [Study on Content Determination of Lead and Arsenic in Four Traditional Tibetan Medicine Prescription Preparations by Wet Digestion Flow Injection-Hydride Generation-Atomic Absorption Spectrometry].

    Science.gov (United States)

    Zheng, Zhi-yuan; Du, Yu-zhi; Zhang, Ming; Yu, Ming-jie; Li, Cen; Yang, Hong-xia; Zhao, Jing; Xia, Zheng-hua; Wei, Li-xin

    2015-04-01

    Four common traditional tibetan medicine prescription preparations "Anzhijinghuasan, Dangzuo, Renqingchangjue and Rannasangpei" in tibetan areas were selected as study objects in the present study. The purpose was to try to establish a kind of wet digestion and flow injection-hydride generation-atomic absorption spectrometry (FI-HAAS) associated analysis method for the content determinations of lead and arsenic in traditional tibetan medicine under optimized digestion and measurement conditions and determine their contents accurately. Under these optimum operating conditions, experimental results were as follows. The detection limits for lead and arsenic were 0.067 and 0.012 µg · mL(-1) respectively. The quantification limits for lead and arsenic were 0.22 and 0.041 µg · mL(-1) respectively. The linear ranges for lead and arsenic were 25-1,600 ng · mL(-1) (r = 0.9995) and 12.5-800 ng · mL(-1) (r = 0.9994) respectively. The degrees of precision(RSD) for lead and arsenic were 2.0% and 3.2% respectively. The recovery rates for lead and arsenic were 98.00%-99.98% and 96.67%-99.87% respectively. The content determination results of lead and arsenic in four traditional tibetan medicine prescription preparations were as fol- lows. The contents of lead and arsenic in Anzhijinghuasan are 0.63-0.67 µg · g(-1) and 0.32-0.33 µg · g(-1) in Anzhijinghua- san, 42.92-43.36 µg · g(-1) and 24.67-25.87 µg · g(-1) in Dangzuo, 1,611. 39-1,631.36 µg · g(-1) and 926.76-956.52 µg- g(-1) in Renqing Changjue, and 1,102.28-1,119.127 µg-g(-1) and 509.96-516.87 µg · g(-1) in Rannasangpei, respectively. This study established a method for content determination of lead and arsenic in traditional tibetan medicine, and determined the content levels of lead and arsenic in four tibetan medicine-prescription preparations accurately. In addition, these results also provide the basis for the safe and effective use of those medicines in clinic.

  19. Study on Magnolia Cream Prescription Screening and Preparation%厚朴乳膏处方筛选及制备工艺的研究与开发

    Institute of Scientific and Technical Information of China (English)

    翁德会; 毛淑芳; 程弘夏; 许腊英

    2015-01-01

    Abstracts:Objective Puepose honokiol components has bactericidal, anti -inflammatory, eliminating dampness, antipruritic effect, through the preparation of cream on the extract was developed using.Methods on the basis of characteristics and cream base of magnolol and honokiol, the prescription composition, screening, and the preparation technology was studied, through the inspection of appearance, the drug transdermal, consistency and stability index, screening the best prescription composition, and preparation of Magnolia officinalis cream. Results Magnolia cream consists of the proportion of preparation, good reproducibility, cream Kizawa Jung, even delicate, consistency is appropriate, easy coating, good stability, absorption through the skin is good, can be regarded as the best proportion to prepare the Magnolia cream.Conclusions It can be used as a new preparation for the development and utilization.%目的:厚朴酚性成分具有杀菌、消炎、燥湿、止痒等作用,通过制备乳膏对其提取物进行开发利用。方法根据厚朴酚、和厚朴酚的特点及乳膏基质的特点,筛选处方组成,并对制备工艺进行研究,通过对乳膏的外观性状、透皮、稠度和稳定性等指标进行考察,筛选最佳的处方组成,并制备厚朴乳膏。结果由该比例的组成制备的厚朴乳膏,重现性好,乳膏色泽较纯正,均匀细腻,稠度适宜,易涂布,稳定性好、透皮吸收等均较好,可以作为最佳配比来制备厚朴乳膏。结论厚朴乳膏可以作为一种新制剂进行开发利用。

  20. Novel technology for sewage sludge utilization: preparation of amino acids chelated trace elements (AACTE) fertilizer.

    Science.gov (United States)

    Liu, Yangsheng; Kong, Sifang; Li, Yaqiong; Zeng, Hui

    2009-11-15

    This study developed a novel technology for sewage sludge utilization. The bacteria proteins in the sewage sludge were extracted to produce the amino acid chelated trace elements (AACTE) fertilizer by virtue of several chemical processes. Firstly, the sewage sludge was hydrolyzed under hot hydrochloric acid solution to obtain protein solution. The effects of hydrolysis temperature, reaction time and pH on the extraction ratio of protein from the sewage sludge were investigated. Secondly, the protein solution was further hydrolyzed into amino acids under hot acid condition. The effects of the HCl dosage, hydrolysis temperature and reaction time on the yields of amino acids were investigated in detail. Thirdly, the raw amino acids solution was purified by activated carbon decolorization and glacial acetic acid dissolution. Finally, the purified amino acids were used to produce the AACTE fertilizer by chelating with trace elements. Results showed that, under optimum hydrolysis conditions, 78.5% of protein was extracted from the sewage sludge and the amino acids yield was 10-13 g per 100g of dry sludge. The AACTE fertilizer produced was in accordance with China Standard for Amino Acids Foliar Fertilizer. This novel technology is more environmentally friendly compared with the conventional sludge treatments.

  1. 甲基莲心碱栓剂处方及工艺优选%Optimization of Prescription and Preparation Technology for Neferine Sup-pository

    Institute of Scientific and Technical Information of China (English)

    张翔; 宋金春

    2016-01-01

    目的:优选制备甲基莲心碱栓剂的处方工艺。方法:以栓剂外观及累积释药百分率为考察指标,采用正交试验法筛选以硬脂酸聚烃氧(40)酯为主体的水溶性栓剂最佳处方。考察成型温度及吐温-80含量对栓剂质量的影响。结果:优选出的最佳处方组成为硬脂酸聚烃氧(40)酯∶聚乙二醇2000∶甘油(7∶3∶1)。最佳成型温度为65℃,吐温-80最适宜的含量为1.5%。结论:该栓剂外观完整光滑,溶出率高,处方设计合理,制备工艺可行。%Objective: To optimize the formulation of neferine rectal suppository. Methods: The orthog-onal design test was used to select the optimum prescription of the water soluble suppository with S-40 as the main ingredient based on appearance and dissolution rate. Next, the influences of molding temperature and tween-80 content on the quality of neferine rectal suppository were also investigated. Results: The best prescription and proportion of neferine rectal suppository was S-40∶PEG-2000∶glycerol at 7∶3∶1. The optimal molding temperature was 65℃, the most suitable content of tween-80 was 1.5%. Conclusion: The prepared suppository is smooth in appearance with high cumulative rate of drug release. This optimized prescription is rational. The preparation technique is easy and practicable.

  2. Utilization of wheat straw for the preparation of coated controlled-release fertilizer with the function of water retention.

    Science.gov (United States)

    Xie, Lihua; Liu, Mingzhu; Ni, Boli; Wang, Yanfang

    2012-07-18

    With the aim of improving fertilizer use efficiency and minimizing the negative impact on the environment, a new coated controlled-release fertilizer with the function of water retention was prepared. A novel low water solubility macromolecular fertilizer, poly(dimethylourea phosphate) (PDUP), was "designed" and formulated from N,N'-dimethylolurea (DMU) and potassium dihydrogen phosphate. Simultaneously, an eco-friendly superabsorbent composite based on wheat straw (WS), acrylic acid (AA), 2-acryloylamino-2-methyl-1-propanesulfonic acid (AMPS), and N-hydroxymethyl acrylamide (NHMAAm) was synthesized and used as the coating to control the release of nutrient. The nitrogen release profile and water retention capacity of the product were also investigated. The degradation of the coating material in soil solution was studied. Meanwhile, the impact of the content of N-hydroxymethyl acrylamide on the degradation extent was examined. The experimental data showed that the product with good water retention and controlled-release capacities, being economical and eco-friendly, could be promising for applications in agriculture and horticulture.

  3. Phosphite determination in fertilizers after online sequential sample preparation in a flow injection system.

    Science.gov (United States)

    Dametto, Patrícia Roberta; Franzini, Vanessa Pezza; Gomes Neto, José Anchieta

    2007-07-25

    A flow injection spectrophotometric system is proposed for phosphite determination in fertilizers by the molybdenum blue method after the processing of each sample two times on-line without and with an oxidizing step. The flow system was designed to add sulfuric acid or permanganate solutions alternately into the system by simply displacing the injector-commutator from one resting position to another, allowing the determination of phosphate and total phosphate, respectively. The concentration of phosphite is obtained then by difference between the two measurents. The influence of flow rates, sample volume, and dimension of flow line connecting the injector-commutator to the main analytical channel was evaluated. The proposed method was applied to phosphite determination in commercial liquid fertilizers. Results obtained with the proposed FIA system were not statistically different from those obtained by titrimetry at the 95% confidence level. In addition, recoveries within 94 and 100% of spiked fertilizers were found. The relative standard deviation (n = 12) related to the phosphite-converted-phosphate peak alone was

  4. Prescriptive unitarity

    Science.gov (United States)

    Bourjaily, Jacob L.; Herrmann, Enrico; Trnka, Jaroslav

    2017-06-01

    We introduce a prescriptive approach to generalized unitarity, resulting in a strictly-diagonal basis of loop integrands with coefficients given by specifically-tailored residues in field theory. We illustrate the power of this strategy in the case of planar, maximally supersymmetric Yang-Mills theory (SYM), where we construct closed-form representations of all ( n-point N k MHV) scattering amplitudes through three loops. The prescriptive approach contrasts with the ordinary description of unitarity-based methods by avoiding any need for linear algebra to determine integrand coefficients. We describe this approach in general terms as it should have applications to many quantum field theories, including those without planarity, supersymmetry, or massless spectra defined in any number of dimensions.

  5. Prescription and

    Directory of Open Access Journals (Sweden)

    David Calderón-Guzmán

    2016-03-01

    Full Text Available Background: The knowledge about the pattern of prescription and consumption of solid oral drugs dispensed as unitary doses (UD in Mexico is sparing. Purpose: The aim of this study was to describe the pattern of prescription and consumption of solid oral drugs dispensed as unitary doses (UD in a third level private hospital of Mexico. A retrospective study of a 60-month period (from 2007 to 2011 was carried out to know the pattern of drugs dispensed as UD in a third level hospital. Results: Among the principal drugs consumed were analgesic, antihypertensive, antibiotic, anti-inflammatory, antiepileptic, and diuretics. The dispensation of drugs per year was as follows: 181 drugs with 85,167 UD in 2007; 199 with 90,519 UD in 2008; 193 with 101,479 UD in 2009; 195 with 100,798 UD in 2010; and 198 with 103,913 UD in 2011. Conclusion: The findings confirmed that prescription and consumption of unitary doses in the hospitalization service increased, and revealed the extensive use of analgesics as the principal prescribed drug in this kind of hospital.

  6. Evaluation of Antitumor, Immunomodulatory and Free Radical Scavenging Effects of A New Herbal Prescription Seaweed Complex Preparation

    Institute of Scientific and Technical Information of China (English)

    LIU Xin; SHAO Changlun; KONG Wenwen; FANG Yuchun; WANG Changyun

    2013-01-01

    Seaweed Complex Preparation (SCP) is a clinical traditional Chinese medicine preparation which is composed of seven traditional Chinese herbs,and it has been used for treatment of lung cancer,liver cancer and digestive cancer.However,little information is available about the pharmacodynamic basis.The antitumor,immunomodulatory and free radical scavenging effects of SCP were evaluated in this study.Transplanted tumor in vivo method was used to determine the antitumor effect.The effects on splenocyte proliferation and phagocytosis of macrophages in tumor-bearing mice were measured by the MTT method and the phagocytizing cock red blood cell (CRBC) method respectively.The scavenging activities of SCP on DPPH and hydroxyl radicals in vitro were investigated.It was found that the medium-dose and high-dose of SCP could significantly inhibit the growth of transplanted hepatic tumor of murine hepatocarcinoma cell line H22,and promote proliferation of splenocytes and phagocytosis of macrophages.SCP possessed noticeable scavenging activities on DPPH and hydroxyl radicals.The antitumor effects of SCP might be achieved by improving immune system and scavenging free radicals,which is in accordance with the viewpoint of traditional Chinese medicine in promoting the body resistance and eliminating pathogenic factors for cancer treatment.

  7. 红霉素自乳化制剂处方研究%Study on Erythromycin Self-Microemulsifying Preparation Prescription

    Institute of Scientific and Technical Information of China (English)

    匡扶; 肖廷超; 朱照静; 钱妍

    2013-01-01

    Objective To study the erythromycin self-microemulsifying drug delivery system (EM-SMEDDS) and to explore its optimal prescription proportioning ratio.Methods The solubility of EM in different oil phases,emulsifiers and co-emulsifiers were detected for selecting the solubility,which with the high solubility was spared.The pseudo-ternary phase diagrams were drawned by the titration method.The proportion of the fomula compositions was detemined.The influence of the charging sequence on the mean particle diameter and the particle diameter distribution of EM-SMEDDS was investigated.The uniform design was adopted to investagte the influence of the preparation temperature,proportion of various compositions,proportion of drug loading capacity and oil phase on the mean particle diameter and the particle diameter distribution.By using mean particle size,particle size distribution and dispersing time as the evaluation indexes,the optimal EM-SMEDDS prescription was screened out.Results Among the prescription,the mixed emulsifier consisted of the oil phase isopropylmyristate(IPM),polyoxyethylated castor oil (cremophor EL) and polyethylene glycol (peg)-8-octylic acid/decanoic acid glycerol ester(Labrasol) could obtain the better emulsificatin effect.In the preparing method,the mixed emulsifier was first prepared,then the mixed emulsifier was mixed with the oil phase,finally the drug was added.The prepared EM-SMEDDS had the mean droplet diameter of less than 50nm.Conclusion The optimal prescription proportioning ratio of EM-SMEDDS is IPM as the oil phase,the mass ratio of the oil phase and the mixed emulsfier was 3 ∶ 7,the mass ratio of LAS and cremorphor E was 7 ∶ 13 with the drug loading capacity of 10%.%目的 研究红霉素自乳化制剂(EM-SMEDDS),探求其最佳处方配比.方法 测定红霉素在各种油相、乳化剂和组乳化剂中的溶解度,选择溶解度高者备用;采用滴定法绘制了油-乳化剂/助乳化剂-水体系伪三元相图,确定处

  8. Preparation of a nanosized micro element fertilizer formulation by using gamma-irradiation technique

    Energy Technology Data Exchange (ETDEWEB)

    Park, Hae Jun; Kim, Hwa Jung [Korea Atomic Energy Research Institute, Jeongeup (Korea, Republic of)

    2010-12-15

    In this study, we addressed a novel nanosized curdlan-silica complex, which is curdlan bound to silica, for the development of a sustain-releasing micro element fertilizer formulation. The complex was obtained as follow steps: First, Curdlan polymer, sodium silicate (Na{sub 2}SiO{sub 3}) and isopropyl alcohol were dissolved in DDW. Next the resultant solution was irradiated by {sup 60}Co gamma-irradiator (150 TBq of capacity: ACEL, Canada). Then MgSO{sub 4} was treated with the resultant solution. The obtained colloidal solution was dried by freeze dryer. Finally, we obtained a novel nanosized curdlan-silica formulation containing MgSO{sub 4} from the colloidal solution. The morphology of the complex was characterized by using scanning electron microscopy (SEM) and transmission electron microscopy (TEM). The nanosized curdlan-silica complex has particle size ranging from 20 to 80nm and high stability. Our results suggested that the nano-complex can be applicable to use in various sustain-releasing formulation formulation for pesticide delivery system (PDS)

  9. Soil organic matter and nitrogen cycling in response to harvesting, mechanical site preparation, and fertilization in a wetland with a mineral substrate

    Science.gov (United States)

    James W. McLaughlin; Margaret R. Gale; Martin F. Jurgensen; Carl C. Trettin

    2000-01-01

    Forested wetlands are becoming an important timber resource in the Upper Great Lakes Region of the US. However, there is limited information on soil nutrient cycling responses to harvesting and post-harvest manipulations (site preparation and fertilization). The objective of this study was to examine cellulose decomposition, nitrogen mineralization, and soil solution...

  10. Medical prescription pitfalls of uncomplicated urinary tract infections ...

    African Journals Online (AJOL)

    user

    identify pitfalls in medical prescriptions of uncomplicated .... encourage laboratory tests to support antibiotic drug treatment. ... relevant systems such as prescriptions monitoring and adverse drug ... registration house officer year: how prepared.

  11. Opioid Basics: Prescription Opioids

    Science.gov (United States)

    ... Injury Violence Prevention WISQARS (Injury & Death Data) Prescription Opioids Recommend on Facebook Tweet Share Compartir Prescription opioids ... overdose before they start. Risk Factors for Prescription Opioid Abuse and Overdose Research shows that some risk ...

  12. Prescription Drug Abuse

    Science.gov (United States)

    ... over-the-counter medications. National Institute on Drug Abuse. http://www.drugabuse.gov/publications/drugfacts/prescription-over-counter- ... 2015. Prescription drug abuse. National Institute on Drug Abuse. http://www.drugabuse.gov/publications/research-reports/prescription-drugs/ ...

  13. Prescription Drug Profiles PUF

    Data.gov (United States)

    U.S. Department of Health & Human Services — This release contains the Prescription Drug Profiles Public Use Files (PUFs) drawn from Medicare prescription drug claims for the year of the date on which the...

  14. Prescription Drug Abuse

    Science.gov (United States)

    ... what the doctor prescribed, it is called prescription drug abuse. It could be Taking a medicine that ... purpose, such as getting high Abusing some prescription drugs can lead to addiction. These include opioids, sedatives, ...

  15. 聚氨酯包膜缓释肥的制备及性能的研究%Preparation and Properties of Polyurethane Coated Slow Release Fertilizer

    Institute of Scientific and Technical Information of China (English)

    宫涛; 杨树竹

    2014-01-01

    Polyurethane coated slow release fertilizer was prepared with solvent free spraying. Influence of spra-ying proportion on coating amount, wear resistance of enveloped fertilizer and coating amount on slow release per-formance were discussed. The results showed that coating effect was the best when spraying proportion of polyure-thane prepolymer and chain extender was 7�40∶1 , the coating amount was 7�23%, the initial solubility of slow re-lease fertilizers was 10�0% to 12�5%, the slightly solubility was 1�8% to 2�4%. Coated fertilizer particle surface was smooth, evenness and wear resistance was better than the coated fertilizer in Japan.%采用无溶剂喷涂成型法制备了聚氨酯包膜缓释肥,讨论了喷涂比例对包膜量和耐磨性的影响以及不同包膜量对缓释性能的影响。结果表明,聚氨酯预聚体与扩链剂的喷涂比例为7�50∶1、实际包覆量为7�23%时,包膜缓释肥的初溶率范围在10�00%~12�50%、微溶率范围在1�80%~2�40%,包膜效果最好;包覆肥颗粒的表面光滑度、均匀度和耐磨性能好,优于日本产包膜肥。

  16. 油菜叶面肥料制备及其性能试验%Preparation and Performance Test of Rape Foliar Fertilizer

    Institute of Scientific and Technical Information of China (English)

    钱佳; 马永刚; 宋阳; 韩效钊

    2011-01-01

    [Objective] The research aimed to study the preparation of rape foliar fertilizer. [Method] The experiment was carried out for the products. Acute oral toxicity of mouse was studied and fertilizer efficiency test was conducted. [ Result] The mouse acute oral toxicity of the product was median lethal dose. The classification of the toxicity belonged low mammalian toxicity. The fertilizer came up to registration requirment. Experimental results showed that the product could improve the biological characters of rape, and the yield was more than the general comparison and clean water comparison by 7.6% ,6.7%. [ Conclusion] The study provided reference for the preparation of rape foliar fertilizer.%[目的]研制对油菜生长发育增产等有利的叶面肥料.[方法]制备油菜叶面肥料产品,采用急性经口毒性试验和肥效试验.[结果]油菜叶面肥料小鼠急性经口半数致死量(LD50)毒性分级属低毒,符合肥料登记要求.它还可提高油菜开盘度,增加根颈粗,分别比常规对照和清水对照增产7.6%、6.7%.[结论]该研究为油菜叶面肥料的制备提供参考依据.

  17. 复方肝素钠尿囊素外用凝胶的处方及制备工艺研究%Prescription and Preparation of Compound Heparin Sodium and Allantoin Topical Gel

    Institute of Scientific and Technical Information of China (English)

    王宇; 丁平田; 牛华英

    2016-01-01

    目的:研制一种含有肝素钠和尿囊素的复方凝胶外用制剂。方法对原料肝素钠和尿囊素进行了系统性的溶解试验研究,同时进行了辅料卡波姆、防腐剂、增溶剂等的选择及其用量的筛选试验研究。结果确定了复方肝素钠尿囊素外用凝胶剂的优选处方和制备工艺。结论该制剂处方合理、制备工艺重复性良好,易于操作,有进一步开发研究的价值。%Objective To prepare a topical gel of Heparin Sodium and Allantoin. Methods Detailed researching the solubility of API's (Heparin Sodium and Allantoin) and ongoing the selection of excipients of carbomer,preservatives and solubilizers etc. and various quantity researching of all inactive ingredients. Results Established the optimized prescription and suitable manufacturing procedure of Compound Heparin Sodium and Allantoin topical gel. Conclusion The prescription of Compound Heparin Sodium and Allantoin topical gel was reasonable,manufacturing procedure has a good reproducibility,it's easy to prepare,and value to be further developed.

  18. INFLUENCE OF THE PREPARATION CASLLED “VYMPEL” AND MINERAL FERTILIZERS OF NEW GENERATION ON OF SAPERAVI VARIETY

    Directory of Open Access Journals (Sweden)

    Kulyko I. A.

    2015-09-01

    Full Text Available The article presents the results of the studies on the effect of the processing of grape variety Saperavi with a growth regulator called Vimpel with water soluble and foliar fertilizers of new generation - Nutrivant plus and Kelik potassium silicon, both in pure form and in a tank mixture. Processing of bushes was performed three times: after flowering, growth phase of berries (berry of a pea, the beginning of ripening berries. We used Vimpel drug and foliar fertilizers such as Nutrivant plus and Kelik potassium-silicon, both in pure form and in conjunction with Vimpel; it led to a significant increase in weight of the bunch, bush crop and planting yields. The smallest yield increase was provided by Vimpel. However, the combined use of this drug on a background of Kelik silicon- potassium foliar fertilizer and Nutrivant plus led to a greater increase in yield from the bush than when used fertilizers only. Processing of bushes by Vimpel in combination with a foliar application of Kelik potassium-silicon not only led to a significant increase in crop yields from the bush and plantations, but in two cases of the three it contributed to a significant increase of the mass concentration of sugars in the juice of berries. Using Vimpel, together with Nutrivant plus foliar application for two years out of three promoted maximize yields (23.4 and 18.4% with a decrease in sugar content, and in one year - an increase in the harvest of 10.4%, with a significant increase in mass sugar concentration (1.92 g / 100 cm3 or 9.2%. Thus, the processing of Saperavi grapes with a growth regulator called Vimpel and water soluble foliar fertilizers of new generation - Nutrivant plus and Kelik potassium and silicon is an effective method of increasing the yield and quality of Saperavi grapes

  19. Fertilization potential and qualitative characteristics of human spermatozoa after short-term cryostorage at 5 degrees C in two different TEST-yolk buffer preparations.

    Science.gov (United States)

    Zavos, P M; Correa, J R; Foster, C L; Massey, J B; Zarmakoupis-Zavos, P N

    1998-02-01

    Use of the media TEST-yolk buffer (TYB) in semenology today enables the short-term incubation and cryostorage of spermatozoa and its subsequent use in the various assisted reproductive technologies (ART). Preparation of TYB media involves the addition of egg yolk (20% v/v) to a physiological solution of the zwitterion buffers TES and Tris. The TYB is usually thermoprecipitated to remove the majority of the egg yolk globules and other macromolecules from the medium. However, removal of these egg yolk constituents could possibly eliminate or reduce essential factors that could enhance the sperm viability and fertilization potential after short-term dilution and storage. Improvements in the quality of the TYB could add greater benefits to those techniques employed in the various forms of ART. The objectives of the investigation were 1) to study the sperm qualitative characteristics following short-term cryostorage at 5 degrees C in either thermoprecipitated (T-TYB) or non-thermoprecipitated (NT-TYB), and 2) to compare the fertilizing potential of spermatozoa stored for 24 hours at 5 degrees C in the two TYB preparations. In Experiment 1, semen specimens from 15 patients were collected, assessed and split into two aliquots. Sperm specimens were processed by diluting 1:1 (v/v) with the T-TYB or NT-TYB, followed by centrifugation and reconstitution of the specimen to its initial volume with the corresponding TYB medium. Sperm specimens were cryostored for 1, 2, 24, 48 and 72 hours. Samples were taken at each interval and placed in a 37 degrees C water bath and allowed to warm for 15 minutes after each cryostorage interval. Semen specimens were assessed for percentage and grade of motility. The results of this study indicated that, although the NT-TYB yielded better results than the T-TYB, overall those differences were not statistically significant. In Experiment 2, the fertilization potential of spermatozoa recovered after 24 hours of cryostorage in the two TYB

  20. A study on preparation and effect of exercise prescription for fat students in colleges and universities%基于自编运动处方的男性肥胖大学生的实验研究

    Institute of Scientific and Technical Information of China (English)

    金川

    2015-01-01

    In order to improve the health status of fat students in colleges and universities,to achieve sports teaching goal of weight reduction,physical improvement,mental and physical pleasure,this article prepared exercise prescription and made an experiment on fat male students for a period of 12 weeks with Delphi method,experiment and mathematical statistics methods.The results show great differences in body shape,body composition,body function and physical quality between the two groups.It proves that exercise prescription for fat students can improve their health.%为了更好地改善普通高校肥胖学生的体质健康状况,达到减轻体重、提高体质、愉悦身心的体育教学目标,采用特尔菲法、实验法、数理统计法,为体育保健课中肥胖组男性大学生研制了运动处方,并进行了为期12周的运动处方干预实验并检验其效果。结果在身体形态、身体成分、身体机能和身体素质等方面反映出较大的差异。

  1. 复方儿茶止泻方微波提取工艺的研究%Study on Microwave Extraction Technique for Complex Prescription of Catechu Anti-diarrhea Preparation

    Institute of Scientific and Technical Information of China (English)

    毛莹; 赵新峰; 石雪; 高明

    2011-01-01

    目的:研究复方儿茶止泻方的最佳微波提取工艺.方法:以儿茶素含量为检测指标,利用微波技术采用正交实验法研究复方儿茶止泻方的最佳提取工艺.结果:复方儿茶止泻方的最佳工艺条件为微波提取时间20 min,功率480 W,料液比为1:7(g·mL-1).结论:微波提取法可缩短复方中药制剂的生产周期,提高生产效率,节约能源,具有较大的应用价值.%Objective: To study the best microwave extraction technique for complex prescription of catechu anti-diarrhea preparation. Method: Conditions for the microwave extraction were studied by orthogonal experimental design with the content of catechin in the extract as indexes. Result: The best technological conditions of the microwave extraction were using 20 min, 480 W firepower and the ratio of material to liquid was 1: 7. Conclusion:Microwave extraction technique has much value of application by shorten the cycle of produce of complex prescription of Chinese drugs pharmaceutics, and it can be used to elevate the efficiency of production and save resources.

  2. Irrational drug use in India: A prescription survey from Goa

    Directory of Open Access Journals (Sweden)

    Naik D

    2005-01-01

    Full Text Available BACKGROUND: There is concern regarding the irrational production, prescription and use of drugs in India. This study aimed to describe the quality of prescriptions by medical practitioners, including both the layout of the prescription and the type and number of drugs prescribed. MATERIALS AND METHODS: A survey of all prescriptions dispensed at a busy pharmacy in the state of Goa, India, was carried out over a consecutive seven-day period. Each prescription was rated on the basis of a priori and pilot-tested variable list. The prescriptions by private practitioners were compared with those from practitioners in the public healthcare system. RESULTS: Nine hundred and ninety prescriptions were collected. The majority (83.9% were from private practitioners. The quality of the layout of the prescriptions was unsatisfactory: information to identify the practitioner was incomplete in more than a third of the prescriptions and information to identify the patient was incomplete in more than half. Clarity of written instructions on how to take the medicines was unsatisfactory in the majority of prescriptions. Polypharmacy was the norm, with more than half (52.7% the prescriptions containing at least 3 medicines. Forty per cent of prescriptions included a vitamin or tonic preparation and a quarter of the prescriptions included an antibiotic and an analgesic. Over 90% of prescriptions contained only branded medicines. Private practitioners prescribed significantly greater number of medicines and were more likely to prescribe vitamins and antibiotics, and branded medicines. DISCUSSION: This study confirms that the quality of prescriptions, both in terms of layout and the content of the drugs prescribed, is inadequate. There is a need to standardize the format of prescriptions in India so that all essential information is included. There is a need to strengthen an independent mechanism for continuing professional development of practitioners to ensure that

  3. Study on forming prescription and preparation technology of hydrotalcite chewable tablets%铝碳酸镁咀嚼片的处方及制剂工艺研究

    Institute of Scientific and Technical Information of China (English)

    赵宁; 冯锁民

    2011-01-01

    The best prescription of hydrotalcite chewable tablets was hydrotalcite 500 g,lactose 300 g , xylital 200 g,aspartame 5 g and magnesium stearate 10 g. Wet granulation pellet method was adopted to prepare hydrotalcite chewable tablets and get three groups of samples. Then using appearance, the hardness. the difference in taste and the content as evaluation indexes,the quality of hydrotalcite chewable tablets was analyzed. Results indicated the hydrotalcite chewable tablets which producted with this prescription and processing technology have good taste,clean and stable, all around indexes conforms with the regulations. The preparation technology is reasonable and mature,it could be used to full scale production.%铝碳酸镁咀嚼片的最佳处方为:铝碳酸镁500 g,乳糖300 g,木糖醇200 g,阿斯巴甜5 g,硬脂酸镁10 g.采用湿法制粒压片法制备铝碳酸镁咀嚼片,并试制3批样品,以外观、硬度、片重差异、口感、含量等为指标对其质量进行了考察.结果表明,该处方工艺制得的咀嚼片,外观光洁,口感良好,硬度、片重差异、含量等均符合规定.本品处方工艺成熟,适合大批量生产.

  4. 低甲醛脲醛-石膏-膨润土基玉米缓释肥的制备%Preparation of Urea Formaldehyde-Gypsum-Bentonite Based Specialty Slowrelease Fertilizers for Corn

    Institute of Scientific and Technical Information of China (English)

    李娜; 邓跃全; 董发勤; 李丽君; 马春雪

    2013-01-01

    Based on the compound of urea formaldehyde and gypsum as the binder and compound with bentonite, a slow-release system was got, and the reasonable amount of slow-release nitrogen fertilizer (urea-gypsum), available nitrogen fertilizer (ammonium sulfate), phosphorus fertilizer or potassium fertilizer were added in according to the demand for N, P, K in different growth period of corn. Then through the extrusion mixing reaction, screening and granulation, the integration preparation technology, urea formaldehyde-gypsum-bentonite based specialty slow release nitrogen fertilizer and slow release compound fertilizer for corn were prepared. Fertilizers obtained were coated with polyvinyl formal (PVF) respectively, and corresponding coated fertilizers were got. Using the continuous leaching method, the release rates of N, P, K and S in slow release fertilizers were determined and were compared with conventional compound fertilizer, the results showed that the slow release properties of the fertilizers prepared by the integration preparation technology were better.%  以低甲醛脲醛和石膏的有机-无机复合物为粘结剂,与膨润土复配,形成缓释体系,根据玉米不同生长期对N、P、K的需要,合理配比缓效氮肥(尿素石膏)、速效氮肥(硫酸铵)、磷素肥料或钾素肥料的用量,通过挤压混合反应,振动筛分,圆盘造粒一体化制备技术制备低甲醛脲醛-石膏-膨润土基玉米专用缓释氮肥和缓释复合肥,分别用聚乙烯醇缩甲醛包膜(PVF),获得包膜缓释氮肥和包膜缓释复合肥;利用沙柱连续淋溶法对缓释肥料中N、P、K、S 4种养分的释放速率进行了测定,并与常规复合肥对比,结果表明其缓释性能良好。

  5. Reclamation of zinc-contaminated soil using a dissolved organic carbon solution prepared using liquid fertilizer from food-waste composting.

    Science.gov (United States)

    Chiang, Po-Neng; Tong, Ou-Yang; Chiou, Chyow-San; Lin, Yu-An; Wang, Ming-Kuang; Liu, Cheng-Chung

    2016-01-15

    A liquid fertilizer obtained through food-waste composting can be used for the preparation of a dissolved organic carbon (DOC) solution. In this study, we used the DOC solutions for the remediation of a Zn-contaminated soil (with Zn concentrations up to 992 and 757 mg kg(-1) in topsoil and subsoil, respectively). We then determined the factors that affect Zn removal, such as pH, initial concentration of DOC solution, and washing frequency. Measurements using a Fourier Transform infrared spectrometer (FT-IR) revealed that carboxyl and amide were the major functional groups in the DOC solution obtained from the liquid fertilizer. Two soil washes using 1,500 mg L(-1) DOC solution with a of pH 2.0 at 25°C removed about 43% and 21% of the initial Zn from the topsoil and subsoil, respectively. Following this treatment, the pH of the soil declined from 5.4 to 4.1; organic matter content slightly increased from 6.2 to 6.5%; available ammonium (NH4(+)-N) content increased to 2.4 times the original level; and in the topsoil, the available phosphorus content and the exchangeable potassium content increased by 1.65 and 2.53 times their initial levels, respectively.

  6. Getting a prescription filled

    Science.gov (United States)

    ... are located inside of a grocery or large "chain" store. It is best to fill all prescriptions ... be used for long-term medicines and medical supplies. The website should have clear directions for filling ...

  7. Prescription drug misuse.

    Science.gov (United States)

    Monheit, Benny

    2010-08-01

    Recognising and dealing with patients who seek drugs for nonmedical purposes can be a difficult problem in general practice. 'Prescription shoppers' and patients with chronic nonmalignant pain problems are the main people who constitute this small but problematic group. The main drugs they seek are benzodiazepines and opioids. To provide data on current trends in prescription drug abuse and to discuss different strategies on how to deal with this issue in the clinic setting. Misuse of prescription drugs can take the form of injecting oral drugs, selling them on the street, or simply overusing the prescribed amount so that patients run short before the due date and then request extra prescriptions from the doctor. Currently oxycontin and alprazolam are the most abused drugs in Australia. Adequate prescription monitoring mechanisms at the systems level are lacking so we need to rely on our clinical skills and the patient's behaviour pattern over time to detect problematic prescription drug misuse. Management strategies may include saying 'no' to patients, having a treatment plan, and adopting a universal precaution approach toward all patients prescribed drugs of addiction. Among patients with chronic nonmalignant pain, requests for increasing opioid doses need careful assessment to elucidate any nonmedical factors that may be at play.

  8. Reclamation of zinc-contaminated soil using a dissolved organic carbon solution prepared using liquid fertilizer from food-waste composting

    Energy Technology Data Exchange (ETDEWEB)

    Chiang, Po-Neng [Experimental Forest, National Taiwan University, Chushan, Nantou County, 55750, Taiwan (China); Tong, Ou-Yang [Department of Environment Engineering, College of the Environment and Ecology, and The Key Laboratory of the Ministry of Education for Coastal and Wetland Ecosystem, Xiamen University, Xiamen (China); Chiou, Chyow-San; Lin, Yu-An [Department of Environmental Engineering, National Ilan University, Ilan 26047, Taiwan (China); Wang, Ming-Kuang [Department of Animal Science, National Ilan University, Ilan 26047, Taiwan (China); Liu, Cheng-Chung, E-mail: ccliu@niu.edu.tw [Department of Agricultural Chemistry, National Taiwan University, Taipei 10617, Taiwan (China)

    2016-01-15

    Highlights: • Nitrogen, phosphorus, and potassium contents in soil are substantially increased after the DOC washing. • The removal of Zn is dominated by proton replacement at pH 2.0, rather than by complexation with DOC. • The removal of Zn is dominated by DOC complexation between pH 3.0 and pH 5.0. - Abstract: A liquid fertilizer obtained through food-waste composting can be used for the preparation of a dissolved organic carbon (DOC) solution. In this study, we used the DOC solutions for the remediation of a Zn-contaminated soil (with Zn concentrations up to 992 and 757 mg kg{sup −1} in topsoil and subsoil, respectively). We then determined the factors that affect Zn removal, such as pH, initial concentration of DOC solution, and washing frequency. Measurements using a Fourier Transform infrared spectrometer (FT-IR) revealed that carboxyl and amide were the major functional groups in the DOC solution obtained from the liquid fertilizer. Two soil washes using 1,500 mg L{sup −1} DOC solution with a of pH 2.0 at 25 °C removed about 43% and 21% of the initial Zn from the topsoil and subsoil, respectively. Following this treatment, the pH of the soil declined from 5.4 to 4.1; organic matter content slightly increased from 6.2 to 6.5%; available ammonium (NH{sub 4}{sup +}-N) content increased to 2.4 times the original level; and in the topsoil, the available phosphorus content and the exchangeable potassium content increased by 1.65 and 2.53 times their initial levels, respectively.

  9. Fertility Awareness

    Science.gov (United States)

    ... I Help Someone Who's Being Bullied? Volunteering Fertility Awareness KidsHealth > For Teens > Fertility Awareness Print A A A What's in this article? ... español Monitoreo de fertilidad What Is It? Fertility awareness is a way to prevent pregnancy by not ...

  10. The impact of biochars prepared from agricultural residues on phosphorus release and availability in two fertile soils.

    Science.gov (United States)

    Manolikaki, Ioanna I; Mangolis, Argirios; Diamadopoulos, Evan

    2016-10-01

    Biochars have a high variability in chemical composition, which is influenced by pyrolysis conditions and type of biomass. Essential macronutrient P retained in biochar could be released and made available to plants, enhancing plant growth. This study was conducted in order to evaluate whether biochar, produced from agricultural residues, could release P in water, as well as study its potential effect on plant growth and P uptake. Biochar samples were prepared from rice husks, grape pomace and olive tree prunings by pyrolysis at 300 °C and 500 °C. These samples were used for P batch successive leaching experiments in order to determine P release in water. Subsequently, rice husk and grape pomace biochars, produced by pyrolysis at 300 °C, were applied to two temperate soils with highly different pH. A three-month cultivation period of ryegrass (Lolium perenne L.) was studied in threefold replication, while three harvests were accomplished. Treatments comprised control soils (without amendment) and soils amended only with biochar. Results of P leaching tests showed a continuous release of P from all biochars as compared to raw biomass samples, for which the highest P concentrations were detected during the first extraction. Grape pomace and rice husk biochars pyrolyzed at 500 °C showed higher levels of water-extractable P, as compared to their corresponding raw biomass. Biochars, at 500 °C, leached more P in all four extractions, compared to biochars at 300 °C, apart from olive tree prunings biochars, where both pyrolysis temperatures presented a similar trend. Concerning plant yield of ryegrass, rice husk and grape pomace biochars showed positive statistically significant effects on plant yield only in slightly acidic soil in second and third harvests. In terms of P uptake of ryegrass, grape pomace biochars depicted positive significant differences (P < 0.05) in third harvest, in slightly acidic soil, while in first and second harvests positive

  11. Prescription Drug Overdose

    Centers for Disease Control (CDC) Podcasts

    2013-07-02

    In this podcast, Dr. Tom Frieden, CDC Director, discusses the epidemic of prescription drug overdose, especially in women, and what can be done about it.  Created: 7/2/2013 by National Center for Injury Prevention and Control.   Date Released: 3/6/2014.

  12. Medicare Prescription Drug Benefit Manual

    Data.gov (United States)

    U.S. Department of Health & Human Services — The Part D Prescription Drug Benefit Manual (PDBM) is user guide to Part D Prescription Drug Program. It includes information on general provisions, benefits,...

  13. Prescription in Dutch general practice.

    NARCIS (Netherlands)

    Dijk, L. van

    2006-01-01

    The second Dutch National Survey of General Practice (DNSGP-2) has combined registration data on morbidity and prescription, making it possible to unravel diagnosis-specific prescription behaviour of general practitioners(GPs). Prescription rates for different disorders vary considerably, especially

  14. Preparation

    Directory of Open Access Journals (Sweden)

    M.M. Dardir

    2014-03-01

    Full Text Available Some hexanamide-mono and di-linoleniate esters were prepared by the reaction of linolenic acid and hexanamide (derived from the reaction of hexanoic acid and diethanolamine. The chemical structure for the newly prepared hexanamide-mono and di-linoleniate esters were elucidated using elemental analysis, (FTIR, H 1NMR and chemical ionization mass spectra (CI/Ms spectroscopic techniques. The results of the spectroscopic analysis indicated that they were prepared through the right method and they have high purity. The new prepared esters have high biodegradability and lower toxicity (environmentally friendly so they were evaluated as a synthetic-based mud (ester-based mud for oil-well drilling fluids. The evaluation included study of the rheological properties, filtration and thermal properties of the ester based-muds formulated with the newly prepared esters compared to the reference commercial synthetic-based mud.

  15. Fermion field renormalization prescriptions

    OpenAIRE

    Zhou, Yong

    2005-01-01

    We discuss all possible fermion field renormalization prescriptions in conventional field renormalization meaning and mainly pay attention to the imaginary part of unstable fermion Field Renormalization Constants (FRC). We find that introducing the off-diagonal fermion FRC leads to the decay widths of physical processes $t\\to c Z$ and $b\\to s \\gamma$ gauge-parameter dependent. We also discuss the necessity of renormalizing the bare fields in conventional quantum field theory.

  16. 21 CFR 1306.05 - Manner of issuance of prescriptions.

    Science.gov (United States)

    2010-04-01

    ... not prepared in the form prescribed by DEA regulations. (b) An individual practitioner exempted from..., who fills a prescription not prepared in the form prescribed by DEA regulations. (g) An individual... not conform in all essential respects to the law and regulations. A corresponding liability rests upon...

  17. 缓/控释化肥合成研究的新进展%New development of preparation of slow/controlled release fertilizer

    Institute of Scientific and Technical Information of China (English)

    陈建超; 刘华; 刘俊杰; 刘亚青

    2011-01-01

    drawbacks caused by the traditional fertilizer. In this paper, the pollution damage to environment and food safety caused by the traditional fertilizer is briefly pointed out. In contrast, several sorts of slow/controlled release fertilizers such as chemically modified, biochemically modified, physically encapsulated and biochemically & physically encapsulated modified fertilizer,classified according to the manufacture process and slow/controlled release mechanism, are introduced in detail. Furthermore, the prospect of slow/controlled release fertilizer is also proposed.slow/controlled release fertilizer; synthesis; development%缓/控释化肥的合成研究是目前肥料领域发展的热点之一,缓/控释化肥可有效弥补传统肥料带来的诸多缺点.简述了传统肥料对环境和食品安全的危害,根据缓/控释化肥的制造工艺和释放原理,重点介绍了化学型、生物化学型、物理包膜型和生物化学与物理包膜结合型缓/控释化肥合成方法的现状,并对缓/控释化肥的发展进行了展望.

  18. Prescription audit of outpatient attendees of secondary level government hospitals in Maharashtra.

    Science.gov (United States)

    Potharaju, Hanumantha Rao; Kabra, S G

    2011-04-01

    The main objective of the prescription audit of the secondary level government hospitals under the Maharashtra Health Systems Development Project (MHSDP) was to develop a list of essential drugs. Other objectives were to articulate measures for improving the prescription practices and to generate information on the core prescribing indicators proposed by the World Health Organization (WHO). The study was conducted among a representative sample of 31 secondary level hospitals under MHSDP. A copy of the prescription was obtained with the help of a pre-inserted carbon, in a special format. Data for only 'first encounter prescriptions' was collected for all patients attending the Outpatient Department (OPD). About 77 percent of the prescriptions contained only one diagnosis. The average number of drugs per prescription was 3.1. About 60 percent of the drugs were prescribed by generic names and about 23 percent of the prescribed drugs were in combination. About 25 percent of the prescriptions contained at least one injection, while 35 percent contained at least one antibiotic. In 16 percent of the prescriptions a vitamin or tonic was prescribed. About 46 percent of the single ingredient formulations were as per the WHO 2003, Essential Medicines List (EML). Based on the findings of the Prescription Audit an EML was prepared for each category of the secondary level hospitals, for use in the OPD. Prescription audits are useful in generating data on morbidity, which forms the basis for preparing the list of essential medicines. Mechanisms necessary for improving prescription practices are suggested.

  19. From description to prescription

    DEFF Research Database (Denmark)

    McQuaid, Sara Dybris

    From Description to Prescription: Politics of Recognition, Consociational Theory and the Conflict in Northern Ireland. Within academic discourses on Northern Ireland the politics of recognition and particularly the theory of consociational democracy has made a profound impact. First introduced...... politico-cultural antagonisms in Northern Ireland. However, the terms ‘consociationalism’ or ‘consociational democracy’ are wholly absent from political discourses: they are never used in any of the governmental and constitutional documents between 1969 and 2006. As such, juxtaposing academic literature...... to integration, eventually converged in authoritative academic and political discourses....

  20. Effects of Nano-preparation on Growth and Nitrogen Fertilizer Use Efficiency of Cabbage%纳米制剂对小白菜生长及氮肥利用率的影响

    Institute of Scientific and Technical Information of China (English)

    王署娟; 刘强; 宋海星; 荣湘民; 彭建伟; 王小娟; 张振华; 陈利军

    2011-01-01

    为提高肥料利用率,研发环境友好型肥料,从源头上控制农业面源污染,采用土培试验,研究了纳米制剂对小白菜产量、养分吸收量、氮肥利用率、叶片叶绿素含量及部分品质指标的影响.结果表明,氮肥中添加纳米氢醌和纳米茶多酚均可提高小白菜产量和叶片叶绿素含量、增加氮磷钾养分吸收量、提高氮肥利用率,以上效果在纳米制剂添加量增加时更加明显.在本试验所设的4种添加纳米制剂处理中,以4%茶多酚处理的效果最好,与未添加纳米制剂处理相比,小白菜产量增加44.6%,氮肥利用率增加134.1%.添加纳米制剂对小白菜品质的影响却不同,可溶性糖含量变化不大,硝酸盐含量有所提高,维生素C含量也有提高趋势,但干重增加最多的(4%茶多酚)处理维生素C含量并没有提高.总之添加纳米制剂可以提高作物产量并能提高肥料利用率.%In order to improve the fertilizer use efficiency, research and develop environment-friendly fertilizers, which can control the agricultural nonpoint source pollution from the source, a soil pot experiment was taken to study the effects of nano-preparation on the production, nutrient absorption, nitrogen fertilizer use efficiency, leaf chlorophyll content and some quality indexes of cabbage.The results showed that, the production, leaf chlorophyll content, the amount of nutrients (N, P, K) absorption and nitrogen fertilizer use efficiency of cabbage were increased by adding nano-hydroquinone and nano-tea-polyphenols in nitrogen fertilizer, and the higher adding amount of nano-preparation had a more obvious effect.The best effective treatment among the four nano-preparation treatments was the one with 4% tea-polyphenols.The production and nitrogen fertilizer use efficiency of cabbage were increased by 44.5% and 134.1%, respectively.However,the effect of adding nano-preparation on the quality of cabbage was different, the changes of

  1. Blended fertilizers as draw solutions for fertilizer-drawn forward osmosis desalination.

    Science.gov (United States)

    Phuntsho, Sherub; Shon, Ho Kyong; Majeed, Tahir; El Saliby, Ibrahim; Vigneswaran, Saravanamuthu; Kandasamy, Jaya; Hong, Seungkwan; Lee, Sangyoup

    2012-04-17

    In fertilizer-drawn forward osmosis (FDFO) desalination, the final nutrient concentration (nitrogen, phosphorus, potassium (NPK)) in the product water is essential for direct fertigation and to avoid over fertilization. Our study with 11 selected fertilizers indicate that blending of two or more single fertilizers as draw solution (DS) can achieve significantly lower nutrient concentration in the FDFO product water rather than using single fertilizer alone. For example, blending KCl and NH(4)H(2)PO(4) as DS can result in 0.61/1.35/1.70 g/L of N/P/K, which is comparatively lower than using them individually as DS. The nutrient composition and concentration in the final FDFO product water can also be adjusted by selecting low nutrient fertilizers containing complementary nutrients and in different ratios to produce prescription mixtures. However, blending fertilizers generally resulted in slightly reduced bulk osmotic pressure and water flux in comparison to the sum of the osmotic pressures and water fluxes of the two individual DSs as used alone. The performance ratio or PR (ratio of actual water flux to theoretical water flux) of blended fertilizer DS was observed to be between the PR of the two fertilizer solutions tested individually. In some cases, such as urea, blending also resulted in significant reduction in N nutrient loss by reverse diffusion in presence of other fertilizer species.

  2. A prescription fraud detection model.

    Science.gov (United States)

    Aral, Karca Duru; Güvenir, Halil Altay; Sabuncuoğlu, Ihsan; Akar, Ahmet Ruchan

    2012-04-01

    Prescription fraud is a main problem that causes substantial monetary loss in health care systems. We aimed to develop a model for detecting cases of prescription fraud and test it on real world data from a large multi-center medical prescription database. Conventionally, prescription fraud detection is conducted on random samples by human experts. However, the samples might be misleading and manual detection is costly. We propose a novel distance based on data-mining approach for assessing the fraudulent risk of prescriptions regarding cross-features. Final tests have been conducted on adult cardiac surgery database. The results obtained from experiments reveal that the proposed model works considerably well with a true positive rate of 77.4% and a false positive rate of 6% for the fraudulent medical prescriptions. The proposed model has the potential advantages including on-line risk prediction for prescription fraud, off-line analysis of high-risk prescriptions by human experts, and self-learning ability by regular updates of the integrative data sets. We conclude that incorporating such a system in health authorities, social security agencies and insurance companies would improve efficiency of internal review to ensure compliance with the law, and radically decrease human-expert auditing costs. Copyright © 2011 Elsevier Ireland Ltd. All rights reserved.

  3. From description to prescription

    DEFF Research Database (Denmark)

    McQuaid, Sara Dybris

    current prominent position within the academy. Structuring these interpretations alongside evolving constitutional policy, the paper will argue that although consociationalism has developed as an indeterminate research design, the inherent logic of managing diversity on the basis of equality as opposed......From Description to Prescription: Politics of Recognition, Consociational Theory and the Conflict in Northern Ireland. Within academic discourses on Northern Ireland the politics of recognition and particularly the theory of consociational democracy has made a profound impact. First introduced...... by the Dutch political scientist Arend Lijphart in a World Politics article from 1969, it has since increased in importance, both as an authoritative explanatory framework for the institutional design inherent in political agreements and as a desirable approach to manage, balance and potentially dissolve...

  4. PECULIARITIES OF FORMING AGROBIOLOGICAL INDEXES OF REAL FRUITFULNESS ON GRAPE BUSHES SAPERAVI VARIETY UNDER INFLUENSE OF TREATMENT BY “VIMPEL” PREPARATION AND NEW GENERATION FERTILIZER

    Directory of Open Access Journals (Sweden)

    Kulyko I. A.

    2016-02-01

    Full Text Available This article deals with the results of the research work concerning the influence of foliar application of grape of Saperavi variety by soluble fertilizers of new generation-Nutrivant plus and Kelik potassiumsilicon. The influence of these fertilizers on yield and actual fruitfulness have also been investigated. The experiments have been carried out both in pureform and in a tankmixture with growth regulator “VIMPEL”. The treatment by these fertilizers has been done three times in the following period; after flowering, in fruit growth phase,(pea-size berry and in the phase of fruit maturing The foliar treatment in a pure form as well as in a tank mixture led to increase of bunch weight, harvest per bush and the yield capacity of plantation. The influence of fertilizers depended not only on variants of experiment but also on weather conditions of the previous and current year as well as on the previous yield. The negative correlation between the indexes of yield structure of the previous year and the actual fruitfulness of the current year has been revealed. However, the character of these correlative connections depends on many factors and greatly differs according to the year. As a result of these investigations, it was stated that foliar application of Saperavi grape variety by fertilizers of a new generation Nutrivant plus and Kelik potassiumsilicon in a tank mixture with growth regulator “Vimpel” in periods after flowering, berry growth(pea-size berry and at the beginning of berry maturing did not promote a stable and significant increase of the main indexes of an actual fruitfulness. The real increase observed in all experimental variants was achieved mainly due to the increase of the average weight of the bunch

  5. The Danish National Prescription Registry

    DEFF Research Database (Denmark)

    Kildemoes, Helle Wallach; Sørensen, Henrik Toft; Hallas, Jesper

    2011-01-01

    Introduction: Individual-level data on all prescription drugs sold in Danish community pharmacies has since 1994 been recorded in the Register of Medicinal Products Statistics of the Danish Medicines Agency. Content: The register subset, termed the Danish National Prescription Registry (DNPR......), contains information on dispensed prescriptions, including variables at the level of the drug user, the prescriber, and the pharmacy. Validity and coverage: Reimbursement-driven record keeping, with automated bar-code-based data entry provides data of high quality, including detailed information...

  6. [Prescription and drug expenditure in gynecology and obstetrics in Northwest medical units from IMSS].

    Science.gov (United States)

    Torres Gómez, Luis Guillermo; Canales Muñoz, José Luis

    2006-08-01

    Drug prescription is the most frequent medical intervention in Gynecology and Obstetrics; however, studies of prescription profile are limited. In this study, we analyzed differences of expense by drug prescription for gynecologic and obstetrics health problems. It was performed a cross sectional study for one year analysis in each medical area that shape IMSS western district. We calculated spending and consumption coefficients for each drug and therapeutic groups. User coefficients were ordered to compare consumption differences. Besides the statistical ratio of consumption between drugs groups, we described the differences found and analyzed the prescription profile among medical regions. Data related to the expenses in each one of the regions show important differences in each one of the drugs and therapeutic groups. The most common expense for drugs is related to the treatment of osteoporosis, menopause and fertility problems. We also found differences in prescription drug preferences in each therapeutic subgroup. Drug prescription studies are useful as a basis for further specific studies in each pharmacologic subgroup. There are few studies that analyze the drug prescription profile on Gynecology and Obstetrics. In this study it is possible to suppose that medical prescription was not based on known medical evidences; therefore, we must reconsider the need of a permanent actualization and systematic medical evaluation.

  7. 改性酱渣废油制备包膜氮肥及对玉米生长的影响%Preparation of coated nitrogen fertilizer from modified soy sauce residue oil and its influence on maize growth

    Institute of Scientific and Technical Information of China (English)

    景旭东; 毛小云; 阎杰; 林海琳; 梁关生; 廖宗文

    2016-01-01

    [Objective] This study aimed to achieve recycling of soy sauce residue oil, reduce its environ-mental pollution, and expand the resources of slow-release fertilizer material. [Method]Coated nitrogen fertilizer was prepared by epoxy modification of soy sauce residue oil. The structure of the coated film was analyzed by infrared spectroscopy, high-power microscope and scanning electron microscope. The fertiliz-er efficiency was examined in corn pot experiment.[Result]After epoxy modification of the soy sauce res-idue oil, its structure changed which promoted forming of film with dense net structure. In corn pot ex-periment, there were no significant differences in leaf number and chlorophyll content between the test group using coated nitrogen fertilizer ( T1 ) and the control group with normal fertilization ( CK2 ) . The fi-nal leaf area, stem girth and plant height of T1 were significantly different from those of the control group with no fertilization ( CK0 ) and the control group with only phosphorus and potassium but no nitrogen fer-tilization ( CK1 ) , and increased by 9. 5%, 4. 3% and 7. 3% at 60 days respectively compared with CK2. The corn plant fresh weight of T1 was significantly different from those of the other three groups. While the corn plant dry weight of T1 was not significantly different from that of CK2 , it significantly in-creased by 14. 2% and 5. 2% respectively compared to CK0 and CK1 . [Conclusion]Coated nitrogen fer-tilizer could promote maize growth, and is considered slow-releasing in soil.%【目的】解决酱渣废弃物的资源再利用问题,减少其对环境的污染,扩大缓释肥包膜材料的来源。【方法】采用酱渣废油经过一定程度环氧化改性之后制备包膜氮肥,利用红外光谱( FTIR)和高倍显微镜及扫描电镜( SEM)分析包膜层的结构,同时通过玉米盆栽试验进行肥效验证。【结果】酱渣废油改性后结构发生了改变,更利于成膜,且膜层出现致密的网状

  8. Prescription Drugs and Cold Medicines

    Science.gov (United States)

    ... on past-month use for illicit drugs (including marijuana and prescription drugs), alcohol, and tobacco. ... neonatal abstinence syndrome, and provides evidence-based treatment options that have been shown to be safe ...

  9. The Danish National Prescription Registry

    DEFF Research Database (Denmark)

    Kildemoes, Helle Wallach; Toft Sørensen, Henrik; Hallas, Jesper

    2011-01-01

    Introduction: Individual-level data on all prescription drugs sold in Danish community pharmacies has since 1994 been recorded in the Register of Medicinal Products Statistics of the Danish Medicines Agency. Content: The register subset, termed the Danish National Prescription Registry (DNPR...... on the dispensed drug. Conclusion: The possibility of linkage with many other nationwide individual-level data sources renders the DNPR a very powerful pharmacoepidemiological tool...

  10. Antipsychotics dosage and antiparkinsonian prescriptions

    Directory of Open Access Journals (Sweden)

    Gasquet Isabelle

    2007-09-01

    Full Text Available Abstract Background To study the link between the dosage of several antipsychotics and the prescription of antiparkinsonians in an observational study. Methods In the context of a national naturalistic prospective observational study, a database containing all the prescriptions from 100 French psychiatrists during the year 2002 was analysed. The inclusion criteria were a diagnosis of schizophrenia or schizoaffective disorder and age over 18. The mean dosage of antipsychotics with and without antiparkinsonians was compared. Since there were multiple prescriptions for a given subject, generalised mixed linear models were also used to study the link between antiparkinsonian prescription and antipsychotic dosage. Results antiparkinsonians were prescribed to 32,9% of the patients. Two groups of antipsychotics were observed relating to differences in dosage when an antiparkinsonian was co prescribed or not : a first group, where the mean dosage was higher with antiparkinsonians (risperidone, amisulpride and haloperidol and a second group (clozapine, olanzapine, in which antiparkinsonian co prescription was not related to the dosage of antipsychotics. Conclusion As a conclusion, it can be said that it is important to consider the dosage and the type of antipsychotic in the treatment of patients suffering of schizophrenia, because neurological side effects are frequent and can impair quality of life. Moreover the prescription of antiparkinsonians can lead to different side effects such anticholinergic effects.

  11. [Innovation and practice of component structure theory on material basis of traditional Chinese medicine prescriptions].

    Science.gov (United States)

    Feng, Liang; Zhang, Ming-Hu; Gu, Jun-Feil; Wu, Chan; Jia, Xiao-Bin

    2013-11-01

    The component structure theory on material basis of traditional Chinese medicine prescriptions provides a new research thought and method for studies on traditional Chinese medicine prescriptions in line with integrated and systemic characteristics of traditional Chinese medicine. Through years of exploration and accumulation, studies on component structures have made achievements. On the basis of summarizing the component structure development of material basis of traditional Chinese medicine prescriptions, we systematically explained the background of component structures and their roles and progress in quality control of traditional Chinese medicine prescriptions and modern innovative traditional Chinese medicine preparations. Studies on component structures promote the changes in material basis of traditional Chinese medicine prescriptions, and point out the direction for the modernization development of traditional Chinese medicine prescriptions.

  12. Analysis of prescription database extracted from standard textbooks of traditional Dai medicine

    Directory of Open Access Journals (Sweden)

    Zhang Chuang

    2012-08-01

    Full Text Available Abstract Background Traditional Dai Medicine (TDM is one of the four major ethnomedicine of China. In 2007 a group of experts produced a set of seven Dai medical textbooks on this subject. The first two were selected as the main data source to analyse well recognized prescriptions. Objective To quantify patterns of prescriptions, common ingredients, indications and usages of TDM. Methods A relational database linking the prescriptions, ingredients, herb names, indications, and usages was set up. Frequency of pattern of combination and common ingredients were tabulated. Results A total of 200 prescriptions and 402 herbs were compiled. Prescriptions based on "wind" disorders, a detoxification theory that most commonly deals with symptoms of digestive system diseases, accounted for over one third of all prescriptions. The major methods of preparations mostly used roots and whole herbs. Conclusion The information extracted from the relational database may be useful for understanding symptomatic treatments. Antidote and detoxification theory deserves further research.

  13. Effect of organic fertilizers prepared from organic waste materials on the production of antibacterial volatile organic compounds by two biocontrol Bacillus amyloliquefaciens strains.

    Science.gov (United States)

    Raza, Waseem; Wei, Zhong; Ling, Ning; Huang, Qiwei; Shen, Qirong

    2016-06-10

    Three organic fertilizers made of different animal and plant waste materials (BOFs) were evaluated for their effects on the production of antibacterial volatile organic compounds (VOCs) by two Bacillus amyloliquefaciens strains SQR-9 and T-5 against the tomato wilt pathogen Ralstonia solanacearum (RS). Both strains could produce VOCs that inhibited the growth and virulence traits of RS; however, in the presence of BOFs, the production of antibacterial VOCs was significantly increased. The maximum inhibition of growth and virulence traits of RS by VOCs of T-5 and SQR-9 was determined at 1.5% BOF2 and 2% BOF3, respectively. In case of strain T-5, 2-nonanone, nonanal, xylene, benzothiazole, and butylated hydroxy toluene and in case of strain SQR-9, 2-nonanone, nonanal, xylene and 2-undecanone were the main antibacterial VOCs whose production was increased in the presence of BOFs. The results of this study reveal another significance of using organic fertilizers to improve the antagonistic activity of biocontrol agents against phytopathogens.

  14. Flexibility in insulin prescription

    Directory of Open Access Journals (Sweden)

    Sanjay Kalra

    2016-01-01

    Full Text Available This communication explores the concept of flexibility, a propos insulin preparations and insulin regimes used in the management of type 2 diabetes. The flexibility of an insulin regime or preparation is defined as their ability to be injected at variable times, with variable injection-meal time gaps, in a dose frequency and quantum determined by shared decision making, with a minimal requirement of glucose monitoring and health professional consultation, with no compromise on safety, efficiency and tolerability. The relative flexibility of various basal, prandial and dual action insulins, as well as intensive regimes, is compared. The biopsychosocial model of health is used to assess the utility of different insulins while encouraging a philosophy of flexible insulin usage.

  15. Using Simulation to Improve First-Year Pharmacy Students' Ability to Identify Medication Errors Involving the Top 100 Prescription Medications.

    Science.gov (United States)

    Atayee, Rabia S; Awdishu, Linda; Namba, Jennifer

    2016-06-25

    Objective. To evaluate first-year pharmacy students' ability to identify medication errors involving the top 100 prescription medications. Design. In the first quarter of a 3-quarter pharmacy self-care course, a didactic lecture on the most common prescribing and dispensing prescription errors was presented to first-year pharmacy students (P1) in preparation for a prescription review simulation done individually and as a group. In the following quarter, they were given a formal prescription review workshop before a second simulation involving individual and group review of a different set of prescriptions. Students were evaluated based on the number of correctly checked prescriptions and a self-assessment of their confidence in reviewing prescriptions. Assessment. All 63 P1 students completed the prescription review simulations. The individual scores did not significantly change, but group scores improved from 79 (16.2%) in the fall quarter to 98.6 (4.7%) in the winter quarter. Students perceived improvement of their prescription checking skills, specifically in their ability to fill a prescription on their own, identify prescribing and dispensing errors, and perform pharmaceutical calculations. Conclusion. A prescription review module consisting of a didactic lecture, workshop and simulation-based methods to teach prescription analysis was successful at improving first year pharmacy students' knowledge, confidence, and application of these skills.

  16. Fertility, mortality, milk output, and body thermoregulation of growing Hy-Plus rabbits fed on diets supplemented with multi-enzymes preparation.

    Science.gov (United States)

    Gado, Hany M; Kholif, Ahmed E; Salem, Abdelfattah Z M; Elghandour, Mona M M; Olafadehan, Oluwarotimi A; Martinez, Maricela A; Al-Momani, Ahmed Q

    2016-10-01

    The aim of this study was to evaluate the fertility status, milk output, mortality, and body thermoregulation of rabbit does as affected by different levels of multi-enzyme extracts (EZ) in their diets. A total of 120 Hy-Plus rabbit does were divided into four comparable experimental groups (n = 30 does per group). Animals of each group were divided in six pens (five animals per pen), and each pen was used as an experimental unit. The first group was kept untreated and fed a commercial diet alone without enzyme extracts (EZ0), while the other groups were fed the same diet but supplemented with 1 (EZ1), 3 (EZ3), and 5 (EZ5) kg/ton of enzyme extracts, respectively. Feeding EZ additive increased (P < 0.05) conception and kindling rates, litter size and weight at birth, and litter size and bunny weight at weaning, with decreasing (P < 0.05) abortion rate. Moreover, total milk yield increased (P < 0.05) with increasing level of enzyme supplementation. Pre-weaning mortality decreased (P < 0.05) with EZ inclusion. Signs of vitality (rectal temperature, skin temperature, earlobe temperature, respiration rate, and pulse rate) were improved with EZ inclusion. For all results, 5 kg EZ/ton of feed was more effective than 1 and 3 kg EZ/ton feed. It can be concluded that supplementation of EZ in rabbit diet decreased mortality rate and enhanced fertility status and milk output.

  17. Prescription Program Provides Significant Savings

    Science.gov (United States)

    Rowan, James M.

    2010-01-01

    Most school districts today are looking for ways to save money without decreasing services to its staff. Retired pharmacist Tim Sylvester, a lifelong resident of Alpena Public Schools in Alpena, Michigan, presented the district with a pharmaceuticals plan that would save the district money without raising employee co-pays for prescriptions. The…

  18. Medication safety: Filling your prescription

    Science.gov (United States)

    ... medicines. Also learn what each medicine looks like. Filling Your Prescriptions Your health plan may require you to use certain pharmacies. ... standards. The website should have clear directions for filling or ... seeing you. Make sure your health plan will cover the cost of using the ...

  19. Prescriptive Exercise for Older Adults.

    Science.gov (United States)

    Piscopo, John

    1985-01-01

    In addition to physical benefits, exercise also provides a natural way to sustain mental alertness in the aging individual by supplying oxygen to the brain. A table focuses on 10 specific health-fitness problems with suggested prescriptive exercises designed to ameliorate the condition. (MT)

  20. Therapeutic Audit Of Dermatological Prescriptions

    Directory of Open Access Journals (Sweden)

    Thawani V.R

    1995-01-01

    Full Text Available Dermatological prescribing trends in outdoor patients attending Dermatology Clinic of Govt. Medical College Hospital, Nagpur were studied. In all 190 prescriptions were audited to find number of drugs per prescription, use of generic/brand names, dosage forms, frequency, duration of treatment, dose and categorywise drug consumption. The age and sex distributions of patients and disease distribution were also studied. Polypharmacy was found to be widely prevalent. More drugs were prescribed by brand names than generic. Dosage form, frequency and duration were mentioned in most of the prescriptions; however, doses of the drugs were not, in majority. The major drugs in the prescriptions were antihistaminics followed by antimicrobials , steroids and vitamins. Not much difference was found in sexes attending the Clinic. There were more female patients of acne vulgaris, disseminated lupus erythematosus and Hansen’s disease. More males suffered from scables and tinea infections. There were 4 patients who were prescribed drugs without diagnosis. Except in some cases, the prescribing was relational.

  1. E-prescription across Europe

    DEFF Research Database (Denmark)

    Kierkegaard, Patrick

    2013-01-01

    . The study concludes that member states have varying degrees of health care policy, privacy enforcement and laws concerning data protection, telecommunication services and digital signature with regards to e-Prescription. Interoperability of different systems is only a partial solution. Security...

  2. Sulphate radical generation through interaction of peroxymonosulphate with Co(II) for in-line sample preparation aiming at spectrophotometric flow-based determination of phosphate and phosphite in fertilizers.

    Science.gov (United States)

    Crispino, Carla C; Kamogawa, Marcos Y; Ferreira, José R; Zagatto, Elias A G

    2016-09-01

    An advanced oxidative process relying on the interaction of peroxymonosulphate and cobalt(II) was implemented for generating the sulphate radicals in flow analysis, in order to accomplish in-line sample preparation thus improving the spectrophotometric determination of phosphate and phosphite in liquid foliar fertilizers. To this end, a flow-batch system with a heated chamber was designed. The sample was handled twice, with and without the step of phosphite oxidation to phosphate, and the formed orthophosphate was quantified after interaction with the vanadate-molybdate reagent. Phosphite was determined as the difference in analytical signals corresponding to sample handling with and without the oxidation step. Influence of Co(II) on the peroxymonosulphate activation, reagent concentrations and added volumes, acidity, temperature and heating time were investigated like aiming at to improve analytical recovery and measurement repeatability, as well as the and system ruggedness. The 6.6-20.0mgL(-1) P2O5 standards were in-line prepared from a single stock solution. Detection limits were estimated as 0.8 and 0.1mgL(-1) for P2O5 and P-PO4. Twenty-four samples are were run per hour, and results are were in agreement with those obtained by the official procedure.

  3. 21 CFR 1306.08 - Electronic prescriptions.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 9 2010-04-01 2010-04-01 false Electronic prescriptions. 1306.08 Section 1306.08 Food and Drugs DRUG ENFORCEMENT ADMINISTRATION, DEPARTMENT OF JUSTICE PRESCRIPTIONS General Information... part 1311 of this chapter. (b) A pharmacy may fill an electronically transmitted prescription for a...

  4. Prescription Drug Abuse and Youth. Information Brief.

    Science.gov (United States)

    Department of Justice, Washington, DC. National Drug Intelligence Center.

    Prescription drugs, a category of psychotherapeutics that comprises prescription-type pain relievers, tranquilizers, stimulants, and sedatives, are among the substances most commonly abused by young people in the United States. Prescription drugs are readily available and can easily be obtained by teenagers who abuse these drugs to experience a…

  5. Fertilization in northern forests

    DEFF Research Database (Denmark)

    Hedwall, Per Ola; Gong, Peichen; Ingerslev, Morten

    2014-01-01

    resources into food, health and industrial products and energy. Fertilization in Sweden and Finland is currently practiced by extensive fertilization regimens where nitrogen fertilizers are applied once, or up to three times, during a rotation period, mainly in mature forest. This type of fertilization...

  6. 废刻蚀液与低品位磷矿为原料磷复肥的制备%Preparation of phosphate and compound fertilizer by phosphorite and waste aluminum etching liquid

    Institute of Scientific and Technical Information of China (English)

    毕亚凡; 牟林琳; 徐俊虎; 李亮

    2013-01-01

    为了实现电子行业废酸液资源化和低品位磷矿的高效利用,以废铝刻蚀液和品位为18.34%磷矿为研究对象,制备磷复肥.采用电感耦合等离子原子发射光谱法测定了铝刻蚀液中主要阳离子组成及浓度,X射线荧光光谱法分析了实验磷矿的化学组成及浓度.通过分析产品的有效磷、游离酸以及磷矿石的分解率,研究了分解反应温度、液固比和熟化时间等工艺参数对制备磷复肥过程的影响.结果表明,废铝刻蚀液中有害离子浓度均达到肥料生产用酸的标准,该废铝刻蚀液可作为农用化肥生产的混酸原料;废铝刻蚀液与低品位磷矿粉生产磷复肥是可行的,制得的磷复肥产品中五氧化二磷含量为22.42%,氮含量为0.43%;废铝刻蚀液中的醋酸也参与了反应,但对制备的产品质量无明显的影响;初步确定最佳工艺条件是:反应温度85℃、液固比0.71、熟化时间为14天.利用废铝刻蚀液直接作为磷复肥生产原料,不仅废物得以资源化利用,也降低废渣的产生量,同时也为中低品位磷矿资源利用途径提供了参考.%To realize the recycling use of waste acid fluid and high effective utilization of low-grade phosphorite,phosphate and compound fertilizer were prepared by waste aluminum etching liquid and phosphorite with content of 18.34%.Composition and concentration of main cations of the waste aluminum etching liquid were tested by inductively coupled plasma optical emission spectrometer.Chemical composition and concentration of the experimental phosphorite were analyzed by X-ray fluorescence spectrometer.Reaction temperature,liquid-solid ratio,and curing time were studied during the productive process of the phosphate and compound fertilizer by analyzing available phosphorous and free acid of the prepared fertilizer and decomposition rate of phosphorite.The experimental results show that concentration of harmful ions of the waste

  7. Studies on Preparation and Physico-chemical Properties of Coating-agent for Controlled Release Fertilizer%控释肥包衣剂的制备及理化性质研究

    Institute of Scientific and Technical Information of China (English)

    刘英; 熊海蓉; 祝友; 熊远福; 李霞; 刘俊

    2013-01-01

      为了获得控释肥包衣剂的制备条件、探明其理化性质,以2种树脂为成膜材料,探讨了成膜材料复合比、成膜材料用量、增塑剂用量、乳化剂用量等单因素对控释肥包衣剂制备效果的影响,运用正交试验L9(34)确定了控释肥包衣剂制备的最佳条件;并对其pH、粘度、成膜时间、成膜性、衣膜水溶性、包衣均匀度、包衣脱落率等理化性质进行了测定。结果表明,控释肥包衣剂的最佳制备条件:树脂JZ与BZ复合比1:1.5,成膜材料用量12%,增塑剂用量0.8%,乳化剂用量1.0%,色素用量0.08%,乙酸乙酯用量86.12%。理化性质测定结果显示:pH 5.21,粘度为21.1 MPa/s,成膜性良好,衣膜不溶于水,成膜时间为6 min,包衣均匀度95%,包衣脱落率<8%,表明所制备的控释肥包衣剂理化性质良好。%To obtain the preparation conditions and explore the physico-chemical properties of coating-agent for controlled release fertilizer, the single factor tests of the composite ratio of film-forming materials, the amount of film-forming materials, plasticizer, emulsifier and pigment were made with two resins as the film-forming materials, and the optimal preparation conditions of coating-agent for controlled-fertilizer were determined by orthogonal test L9(34). The physico-chemical properties of the pH, viscosity, film-forming time, film-forming properties, water solubility of coated film, coating uniformity, coating-off rate were measured. The results showed that, the optimal preparation conditions were as follows:the composite ratio (JZ:BZ) was 1:1.5, amount of film-forming materials was 12%, plasticizer was 0.8%, emulsifier was 1.0%, pigment was 0.08% and solvent was 86.12%. Test results of physico-chemical properties showed that, the pH was 5.21, viscosity was 21.1 MPa/s, the film was good and indissolvable in water, the film-forming time was 6 min, coating uniformity was 95%, coating

  8. On the Ideal Quality Control Specification of Compound Prescription -- Taking thought for the New Ingredients Produced in the Single Drugs Combining Process in Compound Prescription

    Institute of Scientific and Technical Information of China (English)

    刘建利

    2002-01-01

    @@ Effectiveness, safety and quality controllability are the three basic and most important premises for evaluating the quality of drugs. Having undergone clinical tests and been verified in thousands of years, the effectiveness and safety of compound prescription, the chief form of medication in TCM, have been proved reliable. Sometimes due to the lack of quality controllability, incorrect drug or method of preparing being used, so poor therapeutic effect can be seen, though diagnosis and prescription are correct. Quality uncontrollability is also one of the important reasons that causes difficulty for TCM preparation to enter international market. In order to ensure the effectiveness and safety of TCM compound prescription and the entering of TCM preparation into international market, strict quality control specifications should be defined. Although wide attention has been paid to this task, how to define the specifications is still under discussion.

  9. [Exercise prescription and nutrition therapy].

    Science.gov (United States)

    Shiota, Masatoshi; Sone, Ryoko; Matsuo, Eriko; Matsubara, Shigeru; Suzuki, Masato

    2014-08-01

    In the report of World Health Organization, the leading global risks for mortality in the world are high blood pressure (12.8%), tobacco use (8.7%), high blood glucose (5.8%), physical inactivity (5.5%), and overweight and obesity (4.8%). Increased blood pressure levels cause the increased morbidity and mortality of chronic diseases, such as stroke, myocardial infarction, chronic kidney disease. Improving the high blood pressure is considered as common challenges around the world. Exercise prescription and nutrition therapy might be important non-pharmacologic therapies in the control of hypertension. Applying these therapies to the general population can help to prevent an increase in blood pressure and decrease elevated blood pressure levels for those with hypertension. Exercise prescription and nutrition therapy are discussed using the international guidelines.

  10. Prescription Painkiller Overdoses PSA (:60)

    Centers for Disease Control (CDC) Podcasts

    2013-07-02

    This 60 second public service announcement is based on the July 2013 CDC Vital Signs report. Prescription painkiller overdoses are an under-recognized and growing problem among women. This program includes things that women and health care providers can do to reduce the risk of overdose.  Created: 7/2/2013 by Centers for Disease Control and Prevention (CDC).   Date Released: 7/2/2013.

  11. Laboratory Testing for Prescription Opioids

    OpenAIRE

    Milone, Michael C.

    2012-01-01

    Opioid analgesic misuse has risen significantly over the past two decades, and these drugs now represent the most commonly abused class of prescription medications. They are a major cause of poisoning deaths in the USA exceeding heroin and cocaine. Laboratory testing plays a role in the detection of opioid misuse and the evaluation of patients with opioid intoxication. Laboratories use both immunoassay and chromatographic methods (e.g., liquid chromatography with mass spectrometry detection),...

  12. Laboratory testing for prescription opioids.

    Science.gov (United States)

    Milone, Michael C

    2012-12-01

    Opioid analgesic misuse has risen significantly over the past two decades, and these drugs now represent the most commonly abused class of prescription medications. They are a major cause of poisoning deaths in the USA exceeding heroin and cocaine. Laboratory testing plays a role in the detection of opioid misuse and the evaluation of patients with opioid intoxication. Laboratories use both immunoassay and chromatographic methods (e.g., liquid chromatography with mass spectrometry detection), often in combination, to yield high detection sensitivity and drug specificity. Testing methods for opioids originated in the workplace-testing arena and focused on detection of illicit heroin use. Analysis for a wide range of opioids is now required in the context of the prescription opioid epidemic. Testing methods have also been primarily based upon urine screening; however, methods for analyzing alternative samples such as saliva, sweat, and hair are available. Application of testing to monitor prescription opioid drug therapy is an increasingly important use of drug testing, and this area of testing introduces new interpretative challenges. In particular, drug metabolism may transform one clinically available opioid into another. The sensitivity of testing methods also varies considerably across the spectrum of opioid drugs. An understanding of opioid metabolism and method sensitivity towards different opioid drugs is therefore essential to effective use of these tests. Improved testing algorithms and more research into the effective use of drug testing in the clinical setting, particularly in pain medicine and substance abuse, are needed.

  13. Cancer and fertility : strategies to preserve fertility

    NARCIS (Netherlands)

    Diedrich, K.; Fauser, B. C. J. M.; Devroey, P.

    2011-01-01

    Fertility preservation is a key component of cancer management in young people. The Fourth Evian Annual Reproduction Workshop Meeting was held in April 2009 to discuss cancer and fertility in young adults. Specialists in oncology, assisted reproduction, embryology and clinical genetics presented pub

  14. Cancer and fertility : strategies to preserve fertility

    NARCIS (Netherlands)

    Diedrich, K.; Fauser, B. C. J. M.; Devroey, P.

    Fertility preservation is a key component of cancer management in young people. The Fourth Evian Annual Reproduction Workshop Meeting was held in April 2009 to discuss cancer and fertility in young adults. Specialists in oncology, assisted reproduction, embryology and clinical genetics presented

  15. Age and Fertility

    Science.gov (United States)

    ... method of assisted reproduction that involves combining an egg with sperm in a laboratory dish. If the egg fertilizes ... produced by the testes that fertilize a woman’s egg. The sperm head carries genetic material (chromosomes), the midpiece produces ...

  16. Plant fertilizer poisoning

    Science.gov (United States)

    Plant fertilizers and household plant foods are used to improve plant growth. Poisoning can occur if someone swallows these products. Plant fertilizers are mildly poisonous if small amounts are swallowed. ...

  17. Fertility Clinic Success Rates

    Science.gov (United States)

    ... and Autism 2013 Assisted Reproductive Technology Fertility Clinic Success Rates Report Recommend on Facebook Tweet Share Compartir 2013 ART Fertility Clinic Success Rates Report [PDF - 1MB] Bookmarks and thumbnails are ...

  18. In vitro fertilization (IVF)

    Science.gov (United States)

    ... medlineplus.gov/ency/article/007279.htm In vitro fertilization (IVF) To use the sharing features on this page, please enable JavaScript. In vitro fertilization (IVF) is the joining of a woman's egg ...

  19. Increased maize yield using slow-release attapulgite-coated fertilizers

    OpenAIRE

    Guan, Yu; Song, Chao; Gan, Yantai; Li, Feng-Min

    2014-01-01

    International audience; Slow-release fertilizers could improve the productivity of field crops and reduce environmental pollution. So far, no slow-release fertilizers are suited for maize cultivation in semiarid areas of China. Therefore, we tested attapulgite-coated fertilizers. Attapulgite-coated fertilizers were prepared by dividing chemical fertilizers into three parts according to the nutrient demand of maize in its three main growth stages and coating each part with a layer of attapulgi...

  20. Increased maize yield using slow-release attapulgite-coated fertilizers

    OpenAIRE

    Guan, Yu; Song, Chao; Gan, Yantai; Li, Feng-Min

    2014-01-01

    International audience; Slow-release fertilizers could improve the productivity of field crops and reduce environmental pollution. So far, no slow-release fertilizers are suited for maize cultivation in semiarid areas of China. Therefore, we tested attapulgite-coated fertilizers. Attapulgite-coated fertilizers were prepared by dividing chemical fertilizers into three parts according to the nutrient demand of maize in its three main growth stages and coating each part with a layer of attapulgi...

  1. 肥料用改性聚乙烯醇包覆膜的制备及其性能的研究%Preparation and properties of modified polyvinyl alcohol film for encapsulation of fertilizer

    Institute of Scientific and Technical Information of China (English)

    于洋; 邹洪涛; 王剑; 徐萌; 刘洋; 张玉龙

    2012-01-01

    The coating materials of slow release fertilizers were prepared by polymerization reaction between polyvinyl alcohol (PVA) and epoxy resin, and their structures were characterized by infrared ray. The water absorption of coatings was measured by the immersion test to determine the optimal modification scheme. In order to study the effect of coating materials, the nitrogen release of coated urea was investigated by a soil incubation method, and the effects of two coated fertilizers (LP40 and HP) are compared. The results show that etherification modified PVA is synthesized by reaction between epoxy groups and hydroxyl, which reduces the amounts of hydroxyls and the water absorption of the modified films. In deionizer water of 20±2℃, the water absorption of the modified film is 1152 g/kg, which is markedly reduced 884 g/kg compared with the pure PVA films. The concentration of PVA is 70 g/kg, the addition of epoxy resin is 25 g/kg(by mass of PVA solution), the reaction temperature is 60℃, and the reaction time is 2 hours, the modified film leads to lower water absorption. The coated fertilizer HP is effective to decrease nitrogen release, but the slowrelease is poor compared with the LP40.%采用有机高分子聚合反应制备缓释肥料的膜材料,对其进行红外表征,并通过浸水试验测定其吸水率,确定最佳改性方案。同时,为了进一步验证包膜材料对肥料养分的缓释作用,通过土柱淋洗试验测定包膜肥料的养分释放量,并将日本包膜肥料LP40与自制包膜肥料HP的缓释性能进行比较。结果表明, 环氧树脂中的环氧基团能与聚乙烯醇中的羟基发生醚化反应,减少分子中羟基数量,降低改性聚乙烯醇膜的吸水性; 在20±2℃的去离子水中,改性聚乙烯醇膜浸水24 h后,最低吸水率为1152 g/kg,比等浓度纯聚乙烯醇低884 g/kg; 聚乙烯醇浓度为70 g/kg,环氧树脂的加入量为25 g/kg(按聚乙烯

  2. 论经方剂型及服用方法的安全性%Relate the Safety in Form of Prepared Drugs and Method of Taking Medicine from Classical Prescription

    Institute of Scientific and Technical Information of China (English)

    吴建红

    2011-01-01

    This paper discussed the safety in form of prepared drugs and method of taking medicine on the basis of ZHANG Zhong-jing's Treatise on Febrile Diseases and Synopsis of the Golden Chamber. Limited dosage form, such as pill, had been used in order to secure that toxic reaction of formulae was reduced and potent action of drugs was palliated. Different method of taking medicine had been adopted in the light of specific conditions,such as the constitution, the age and the drug effect. In a word, the ultimate aim of limited dosage form and different method of taking medicine was eliminating pathogen without damage of health energy.%以《伤寒论》、《金匮要略》为依据,述经方在剂型、服药方法的安全性.张仲景依据药方的峻缓及毒性,给予剂型的限定,多用丸剂意在缓攻或缓治,缓和药力之峻烈之性与降低药物的毒性,以达祛邪不伤正的目的.在临证用方时,根据病人体质的强弱、年龄有长幼和药后疗效,采取不同的服药方法,避免损伤人体的正气.

  3. Impact of a Mandatory Prescription Drug Monitoring Program on Prescription of Opioid Analgesics by Dentists

    OpenAIRE

    Linda Rasubala; Lavanya Pernapati; Ximena Velasquez; James Burk; Yan-Fang Ren

    2015-01-01

    Prescription Drug Monitoring Programs (PDMP) are statewide databases that collect data on prescription of controlled substances. New York State mandates prescribers to consult the PDMP registry before prescribing a controlled substance such as opioid analgesics. The effect of mandatory PDMP on opioid drug prescriptions by dentists is not known. This study investigates the impact of mandatory PDMP on frequency and quantity of opioid prescriptions by dentists in a dental urgent care center. Bas...

  4. Preparation of liquid bacterial fertilizer of phosphate-solubilizing bacteria from food waste-recycling wastewater%餐厨垃圾废水制备液态解磷菌剂研究

    Institute of Scientific and Technical Information of China (English)

    郭新愿; 祁光霞; 王永京; 李雨桥; 张希; 李冬; 任连海

    2016-01-01

    The feasibility of using food waste-recycling wastewater as fermentation substrate for producing liquid phosphate-solubilizing bacillus megaterium fertilizer was investigated. The results showed that bacillus megaterium cultured in the food waste-recycling wastewater reached logarithmic growth stage in as short as 3~4 days of adaptation period, and the number of strains reached the maxima on the 6~7th day. The wastewater II generated from hydrothermal pre-treatment was more suitable to be the fermentation substrate than wastewater I. The strain numbers cultured in wastewater II was 5times of what was cultured in wastewater I (4.8×1015CFU/mL). Salt concentration in the wastewater had great influence on the growth and metabolism of Bacillus megaterium: the strain numbers first increased and then steeply decreased with the increase of NaCl concentration, indicating that the optimal NaCl concentration for bacterial culture was 10g/L. The variation of pH and temperature affected the growth of bacillus megaterium significantly, while shaking speed and strain inoculation volume were not key influencing factors. The optimal culture conditions were pH 8, T=35℃, shaking speed 80r/min, and inoculums of 2%(V/V) as determined by orthogonal experiment. Phosphate-solubilizing fertilizer prepared by food waste-recycling wastewater was able to achieve effective phosphating of immobilized phosphorus: the dry weight of soy beans grown in soils amended with 0.025‰~2.5‰ of phosphate-solubilizing fertilizer was 70.7%~84.5%of that grown in the soil amended with 5%of inorganic fertilizer on weight basis. Moreover, the optimal amended ratio of the microbial fertilizer was 0.25‰.%本研究探讨了餐厨垃圾废水用作发酵基质生产液态解磷巨大芽孢杆菌菌肥的可行性.结果表明,餐厨垃圾废水培养的巨大芽孢杆菌经过3~4d的调整期即进入对数生长期,第6~7d活菌数达到最大,而经过湿热预处理得到的II类废水较I类废水

  5. Cancer and fertility: strategies to preserve fertility.

    Science.gov (United States)

    Diedrich, K; Fauser, B C J M; Devroey, P

    2011-03-01

    Fertility preservation is a key component of cancer management in young people. The Fourth Evian Annual Reproduction Workshop Meeting was held in April 2009 to discuss cancer and fertility in young adults. Specialists in oncology, assisted reproduction, embryology and clinical genetics presented published data and ongoing research on cancer and fertility, with particular focus on strategies to preserve fertility. This report is based on the expert presentations and group discussions, supplemented with publications from literature searches and the authors' knowledge. Fertility preservation should be considered for all young people undergoing potentially gonadotoxic cancer treatment. A variety of options are required to facilitate safe and effective fertility preservation for individual patients. Sperm banking is a simple and low-cost intervention. Embryo cryopreservation is the only established method of female fertility preservation. Oocyte cryopreservation offers a useful option for women without a male partner. Emergency ovarian stimulation and cryopreservation of ovarian tissue (followed by tissue transplantation or in-vitro maturation of oocytes) are experimental techniques for women who require urgent cancer treatment. Further prospective studies are required to validate cryopreservation of oocytes and ovarian tissue, in-vitro maturation of oocytes and new vitrification techniques and to identify any long-term sequelae of slow freezing of embryos.

  6. Soil compaction and fertilization in soybean productivity

    Directory of Open Access Journals (Sweden)

    Beutler Amauri Nelson

    2004-01-01

    Full Text Available Soil compaction and fertilization affect soybean development. This study evaluated the effects of soil compaction and fertilization on soybean (Glycine max cv. Embrapa 48 productivity in a Typic Haplustox under field conditions in Jaboticabal, SP, Brazil. A completely randomized design with a 5 x 2 factorial layout (compaction vs. fertilization, with four replications in each treatment, was employed. Each experimental unit (replicate consisted of a 3.6 m² useful area. After the soil was prepared by cultivation, an 11 Mg tractor passed over it a variable number of times to create five levels of compaction. Treatments were: T0= no compaction, T1= one tractor pass, T2= two, T4= four, and T6= six passes, and no fertilizer and fertilizer to give soybean yields of 2.5 to 2.9 Mg ha-1. Soil was sampled at depths of 0.02-0.05, 0.07-0.10, and 0.15-0.18 m to determine macro and microporosity, penetration resistance (PR, and bulk density (Db. After 120 days growing under these conditions, the plants were analyzed in terms of development (plant height, number of pods, shoot dry matter per plant and weight of 100 seeds and seed productivity per hectare. Soil compaction decreased soybean development and productivity, but this effect was decreased by soil fertilization, showing that such fertilization increased soybean tolerance to soil compaction.

  7. Influence of pharmacists expertise on physicians prescription ...

    African Journals Online (AJOL)

    The influence of pharmacist factors on physician prescription decisions was identified ... Keywords: Physician prescription behaviour, Pharmacist factor, ... addition to the influence of marketing promotion .... from the drug sales, obtaining clinic rental ... also analyzed the current status of pharmacist's ..... the buyer-seller dyad.

  8. 21 CFR 801.109 - Prescription devices.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Prescription devices. 801.109 Section 801.109 Food... DEVICES LABELING Exemptions From Adequate Directions for Use § 801.109 Prescription devices. A device... direct the use of such device, and hence for which “adequate directions for use” cannot be...

  9. Fertilization in northern forests

    DEFF Research Database (Denmark)

    Hedwall, Per Ola; Gong, Peichen; Ingerslev, Morten

    2014-01-01

    resources into food, health and industrial products and energy. Fertilization in Sweden and Finland is currently practiced by extensive fertilization regimens where nitrogen fertilizers are applied once, or up to three times, during a rotation period, mainly in mature forest. This type of fertilization......Forests of northern ecosystems respond slowly to management activities and the possibilities to increase the growth in a short-term perspective and meet swift increases in society's demand for biomass are small. An exception among the silvicultural measures is fertilization which can be applied...... in combination with present management systems and, almost instantly, enhances forest productivity. There may, however, be both economic and environmental constraints to large-scale applications of fertilizers in forest. Here we review the literature concerning biomass production of forests under different...

  10. Fertility Preservation for Female

    Institute of Scientific and Technical Information of China (English)

    Jack Huang; Seang Lin Tan; Ri-Cheng Chian

    2006-01-01

    Preservation of female fertility is an important issue today. However, there are few effective clinical options for preserving female fertility. Firstly, conventional in vitro fertilization (IVF) followed by embryo cryopreservation is an accepted procedure but is not applicable to all women. Embryo freezing is suitable only for women with a male partner and may not be acceptable to some patients due to moral and religious reasons. Ovarian tissue freezing is another option of female fertility preservation but is an invasive procedure and the efficacy of this technique remains to be determined.Oocyte cryopreservation is also method for fertility preservation. Egg freezing is minimally invasive and can avoid the ethical and moral concerns related to cryopreservation of embryos. However, conventional slow freezing/rapid thawing methods are associated with low survival of oocytes. Recent development in vitrification of oocytes appears promising. Therefore, vitrification of unfertilized eggs may be a novel method to preserve female fertility.

  11. FERTILIZER SALES AND SERVICEMAN. TEACHERS COPY.

    Science.gov (United States)

    WIGGS, J.T.; AND OTHERS

    THE PURPOSE OF THIS DOCUMENT IS TO PROVIDE A STUDY GUIDE FOR STUDENTS PREPARING TO BE FERTILIZER SALES AND SERVICEMEN IN A COOPERATIVE EDUCATION PROGRAM. IT WAS DESIGNED BY SUBJECT MATTER SPECIALISTS ON THE BASIS OF RECOMMENDATIONS BY A STATE ADVISORY COMMITTEE, TESTED IN OPERATIONAL PROGRAMS, AND REFINED BY A VOCATIONAL AGRICULTURE TEACHER. UNITS…

  12. Encapsulated Urea-Kaolinite Nanocomposite for Controlled Release Fertilizer Formulations

    National Research Council Canada - National Science Library

    Sempeho, Siafu Ibahati; Kim, Hee Taik; Mubofu, Egid; Pogrebnoi, Alexander; Shao, Godlisten; Hilonga, Askwar

    2015-01-01

    Urea controlled release fertilizer (CRF) was prepared via kaolinite intercalation followed by gum arabic encapsulation in an attempt to reduce its severe losses associated with dissolution, hydrolysis, and diffusion...

  13. Fertilization in echinoderms.

    Science.gov (United States)

    Santella, Luigia; Vasilev, Filip; Chun, Jong T

    2012-08-31

    For more than 150 years, echinoderm eggs have served as overly favored experimental model systems in which to study fertilization. Sea urchin and starfish belong to the same phylum and thus share many similarities in their fertilization patterns. However, several subtle but fundamental differences do exist in the fertilization of sea urchin and starfish, reflecting their phylogenetic bifurcation approximately 500 million years ago. In this article we review some of the seminal and recent findings that feature similarities and differences in sea urchin and starfish at fertilization.

  14. Impact of a Mandatory Prescription Drug Monitoring Program on Prescription of Opioid Analgesics by Dentists.

    Directory of Open Access Journals (Sweden)

    Linda Rasubala

    Full Text Available Prescription Drug Monitoring Programs (PDMP are statewide databases that collect data on prescription of controlled substances. New York State mandates prescribers to consult the PDMP registry before prescribing a controlled substance such as opioid analgesics. The effect of mandatory PDMP on opioid drug prescriptions by dentists is not known. This study investigates the impact of mandatory PDMP on frequency and quantity of opioid prescriptions by dentists in a dental urgent care center. Based on the sample size estimate, we collected patient records of a 3-month period before and two consecutive 3-month periods after the mandatory PDMP implementation and analyzed the data on number of visits, treatment types and drug prescriptions using Chi-square tests. For patients who were prescribed pain medications, 452 (30.6%, 190 (14.1%, and 140 (9.6% received opioid analgesics in the three study periods respectively, signifying a statistically significant reduction in the number of opioid prescriptions after implementation of the mandatory PDMP (p<0.05. Total numbers of prescribed opioid pills in a 3-month period decreased from 5096 to 1120, signifying a 78% reduction in absolute quantity. Prescriptions for non-opioid analgesics acetaminophen increased during the same periods (p<0.05. We conclude that the mandatory PDMP significantly affected the prescription pattern for pain medications by dentists. Such change in prescription pattern represents a shift towards the evidence-based prescription practices for acute postoperative pain.

  15. Prescription Opioid Usage and Abuse Relationships: An Evaluation of State Prescription Drug Monitoring Program Efficacy

    Directory of Open Access Journals (Sweden)

    Richard M. Reisman

    2009-01-01

    Full Text Available Context: The dramatic rise in the use of prescription opioids to treat non-cancer pain has been paralleled by increasing prescription opioid abuse. However, detailed analyses of these trends and programs to address them are lacking.Objective: To study the association between state shipments of prescription opioids for medical use and prescription opioid abuse admissions and to assess the effects of state prescription drug monitoring programs (PDMPs on prescription opioid abuse admissions.Design and Setting: A retrospective ecological cohort study comparing state prescription opioid shipments (source: Automation of Reports and Consolidated Orders Systems database and inpatient admissions for prescription opioid abuse (source: Treatment Episode Data Set in 14 states with PDMPs (intervention group and 36 states without PDMPs (control group for the period 1997–2003.Results: From 1997 to 2003, oxycodone, morphine, and hydrocodone shipments increased by 479%, 100%, and 148% respectively. Increasing prescription oxycodone shipments were significantly associated with increasing prescription opioid admission rates (p 0.001. PDMP states had significantly lower oxycodone shipments than the control group. PDMP states had less increase in prescription opioid admissions per year (p = 0.063. A patient admitted to an inpatient drug abuse rehabilitation program in a PDMP state was less likely to be admitted for prescription opioid drug abuse (Odds ratio = 0.775, 95% Confidence Interval 0.764–0.785.Conclusions: PDMPs appear to decrease the quantity of oxycodone shipments and the prescription opioid admission rate for states with these programs. Overall, opioid shipments rose significantly in PDMP states during the study period indicating a negligible “chilling effect” on physician prescribing.

  16. Fertilizer Use and Water Quality.

    Science.gov (United States)

    Reneau, Fred; And Others

    This booklet presents informative materials on fertilizer use and water quality, specifically in regard to environmental pollution and protection in Illinois. The five chapters cover these topics: Fertilizer and Water Quality, Fertilizer Use, Fertilizers and the Environment, Safety Practices, and Fertilizer Management Practices. Key questions are…

  17. Fertilizer Use and Water Quality.

    Science.gov (United States)

    Reneau, Fred; And Others

    This booklet presents informative materials on fertilizer use and water quality, specifically in regard to environmental pollution and protection in Illinois. The five chapters cover these topics: Fertilizer and Water Quality, Fertilizer Use, Fertilizers and the Environment, Safety Practices, and Fertilizer Management Practices. Key questions are…

  18. [Exploration on eighteen incompatible medicaments of chest pain prescriptions based on association rules mining].

    Science.gov (United States)

    Zhang, Yuhua; Hua, Haoming; Fan, Xinsheng; Wang, Chongjun; Duan, Jinao

    2011-12-01

    To investigate the laws of eighteen incompatible medicaments of the chest pain prescriptions based on association rules mining. The database of chest pain prescription was established and then the chest pain prescriptions composed of eighteen incompatible medicaments were screened. The dynasty, couplet medicines, the property and flavor of drugs and preparation form were analyzed with the frequent item sets and corresponding analysis methods. Eight hundred and fifty chest pain prescriptions were collected, and 88 of them contained eighteen incompatible medicaments, taking 10.3% of all; the applications of ancient and modern chest pain prescriptions containing eighteen incompatible medicaments are significant difference (P dynasty and tang dynasty, are more often used than the modern formulas. The most common anti-drugs is on the Fuzi-Pinellia, Chuanwu-Pinellia; the property and flavor of drugs is bitter cold most closely; the decoction of the formulas is mostly used. Eighteen incompatible medicaments account for about ten percent of the chest pain prescription, not an uncommon side. There are certain rules for application of anti-drug compatibility to treat chest pain.

  19. Correlations in fertility across generations: can low fertility persist?

    Science.gov (United States)

    Kolk, Martin; Cownden, Daniel; Enquist, Magnus

    2014-03-22

    Correlations in family size across generations could have a major influence on human population size in the future. Empirical studies have shown that the associations between the fertility of parents and the fertility of children are substantial and growing over time. Despite their potential long-term consequences, intergenerational fertility correlations have largely been ignored by researchers. We present a model of the fertility transition as a cultural process acting on new lifestyles associated with fertility. Differences in parental and social influences on the acquisition of these lifestyles result in intergenerational correlations in fertility. We show different scenarios for future population size based on models that disregard intergenerational correlations in fertility, models with fertility correlations and a single lifestyle, and models with fertility correlations and multiple lifestyles. We show that intergenerational fertility correlations will result in an increase in fertility over time. However, present low-fertility levels may persist if the rapid introduction of new cultural lifestyles continues into the future.

  20. Fertility treatment and childhood type 1 diabetes mellitus

    DEFF Research Database (Denmark)

    Kettner, Laura Ozer; Matthiesen, Niels Bjerregaard; Ramlau-Hansen, Cecilia Høst

    2016-01-01

    OBJECTIVE: To investigate the association between specific types of fertility treatment and childhood type 1 diabetes mellitus. DESIGN: Nationwide birth cohort study. SETTING: Not applicable. PATIENT(S): All pregnancies resulting in a live-born singleton child in Denmark from 1995 to 2003....... INTERVENTION(S): Not applicable. MAIN OUTCOME MEASURE(S): Childhood type 1 diabetes mellitus identified from redeemed prescriptions for insulin until 2013. RESULT(S): The study included 565,116 singleton pregnancies. A total of 14,985 children were conceived by ovulation induction or intrauterine insemination......, and 8,490 children were conceived by in vitro fertilization or intracytoplasmic sperm injection. During the follow-up period, 2,011 (0.4%) children developed type 1 diabetes mellitus. The primary analyses showed no association between fertility treatment and childhood type 1 diabetes mellitus...

  1. Meticulous Overview on the Controlled Release Fertilizers

    Directory of Open Access Journals (Sweden)

    Siafu Ibahati Sempeho

    2014-01-01

    Full Text Available Owing to the high demand for fertilizer formulations that will exhaust the possibilities of nutrient use efficiency (NUE, regulate fertilizer consumption, and lessen agrophysicochemical properties and environmental adverse effects instigated by conventional nutrient supply to crops, this review recapitulates controlled release fertilizers (CRFs as a cutting-edge and safe way to supply crops’ nutrients over the conventional ways. Essentially, CRFs entail fertilizer particles intercalated within excipients aiming at reducing the frequency of fertilizer application thereby abating potential adverse effects linked with conventional fertilizer use. Application of nanotechnology and materials engineering in agriculture particularly in the design of CRFs, the distinctions and classification of CRFs, and the economical, agronomical, and environmental aspects of CRFs has been revised putting into account the development and synthesis of CRFs, laboratory CRFs syntheses and testing, and both linear and sigmoid release features of CRF formulations. Methodical account on the mechanism of nutrient release centring on the empirical and mechanistic approaches of predicting nutrient release is given in view of selected mathematical models. Compositions and laboratory preparations of CRFs basing on in situ and graft polymerization are provided alongside the physical methods used in CRFs encapsulation, with an emphasis on the natural polymers, modified clays, and superabsorbent nanocomposite excipients.

  2. Monitoring physicians' prescription patterns on electronic health record: the prescription pattern around clinical event (PACE) algorithm.

    Science.gov (United States)

    Yoon, Dukyong; Park, Inwhee; Park, Man Young; Hong, Seung Kwon; Park, Rae Woong

    2013-01-01

    Electronic health records (EHRs) have gained attention as a valuable data source for medical research, as its adoption rate continues to rise. However, no method for the monitoring of physicians' prescription patterns has been established. Since EHR maintain all prescription data as well as clinical events that occur during the care of patients, we hypothesized that a physician's prescription pattern can be monitored from EHR. In this study, we developed a novel algorithm named PACE, Prescription pattern Around Clinical Event. This algorithm analyzes distribution of the prescription of specific drugs around the time of a clinical event. In the proof of concept study, prescription changes with regard to hyperkalemia were well represented by the algorithm, and the observed patterns well correlated with the physician's knowledge on hyperkalemia (Cohen's kappa, 0.457-0.653). We expect that this algorithm can be used to monitor the guideline adherence of physicians.

  3. Family systems and fertility

    NARCIS (Netherlands)

    Moenkediek, Bastian

    2016-01-01

    This thesis studies the role of regional family organization principles, so called family systems, for explaining fertility behaviours in different parts of Europe. Studying family systems and its impact on fertility is important, because many aspects of societal life, such as the organization of we

  4. Medicare Prescription Drug Coverage - General Information

    Data.gov (United States)

    U.S. Department of Health & Human Services — The MMA legislation provides seniors and people with disabilities with the first comprehensive prescription drug benefit ever offered under the Medicare program, the...

  5. Prescription Pain Medicines - An Addictive Path?

    Science.gov (United States)

    ... statistics showed that retail sales of five major painkillers rose 90 percent from 1997 to 2005. The report revealed that ever-increasing amounts of prescription painkillers called opioid analgesics are being used on a ...

  6. CDC Vital Signs: Prescription Painkiller Overdoses (Opioids)

    Science.gov (United States)

    ... reporting and access, integration with electronic health records, proactive unsolicited reporting, incentives for provider use, and interoperability ... – Office of Diversion Control Drugs, Brains, and Behavior: The Science of Addiction Prescription Drugs U.S. Food ...

  7. Prescription drug abuse in the elderly.

    Science.gov (United States)

    Martin, Caren McHenry

    2008-12-01

    The increased use of prescription drugs has brought pain relief too many and often improved the quality of life of elderly patients. But the increase in use and availability of prescription medications-especially controlled substances-brings with it an increased potential for abuse. Studies have shown that intentional abuse of prescription drugs is increasing among all age groups. As the number of persons 65 years of age and older skyrockets with the aging of the baby boomers, experts predict that prescription drug abuse among the elderly also will rise significantly. Efforts to increase awareness of drug abuse among elderly patients, caregivers, and health care practitioners, as well as research into how best to prevent and treat the elderly drug abuser, will be necessary to thwart what could become a significant public health problem.

  8. Assessment of prescription sales in Ukraine

    Directory of Open Access Journals (Sweden)

    N. V. Teterich

    2013-10-01

    Full Text Available Currently, the state of the national health system (health is characterized by a low level of funding for medical and pharmaceutical care and the lack of effective methods of free and preferential dispensing of medicines (drugs and compensation of their value. Thus the most urgent problem arises is unregulated drugs prescription, which is one of the main negative factors behind the rapid spread of self-medication and polypragmasy. Thus, improving drugs prescription dispensing is one of the current challenges of medicine and pharmacy management which should be solved to provide a safe, rational and effective drug therapy. The results of the questionnaire survey of doctors and pharmaceutical workers identified and explored key factors that contribute to a violation of drugs prescription. The authors analyzed the literature on the current state of drugs prescription in Ukraine, which resulted in selected priority issues that need resolution as soon as possible. Established that the main disadvantages of the national health care system is unreasonable approach to state regulation of the relevant system and the low level of funding. This situation prevents rational regulation of free and preferential delivery of drugs, the introduction of obligatory medical insurance and the reimbursement cost of drugs and other modern approaches that are effective in developed countries. Тhe main motive of view of legislative acts to implement strict drugs prescription in Ukraine is a link to international experience, guided by the standards of European and international practices that do not comply with the Law of Ukraine issued on 18.03.2004 № 1629-IV «On the National Program for Adaptation of Ukraine to the European Union, "and points to the disparity modern domestic rule-making European practice. The fundamental problem here is the comparison of the legal, social, financial and economic status of the counter in Ukraine with the countries in which the system

  9. Fertility decline in Paraguay.

    Science.gov (United States)

    Ishida, Kanako; Stupp, Paul; Melian, Mercedes

    2009-09-01

    Recent reproductive health surveys show that the fertility rate in Paraguay decreased precipitously from 4.3 lifetime births per woman in 1995-98 to 2.9 births in 2001-04. In this study, we establish data consistency between the 1998 and 2004 surveys by comparing a series of cohort-specific period rates and use the Bongaarts framework of proximate determinants of fertility to demonstrate that an increase in the contraceptive prevalence rate (CPR) between 1998 and 2004 fully accounts for the fertility decline. Decomposition of rates shows that changes in group-specific CPRs explain a greater proportion of the change in the overall CPR than do changes in population composition by educational attainment, urban residence, region, and language spoken at home. Finally, we show that younger cohorts of women in 2004 reported ideal completed fertility desires of less than 2.9 births, suggesting that the fertility rate is likely to continue to decrease.

  10. [Socioeconomic variables and fertility].

    Science.gov (United States)

    Arguello, O

    1980-08-01

    While making comparative analyses of data collected by the World Fertility Survey regarding Latin America, a group of investigators of CELADE (Centro Latinoamericano de Demografia) realized that the selection of economic variables for the study of fertility had serious limitations. Such limitations did not allow the elaboration of a theory which took into account the complicated process of fertility, in all its socioeconomic, cultural, and psychological manifestations. Thus, this paper intends to lay the theoretical basis for the selection of all relevant variables, distinguishing, for example, the average fertility of women according to area of residence, place of early socialization, migrant status, social status, occupation of husband, level of instruction, occupation, and all changes in occupational activities of women in fertile age.

  11. Off-label prescriptions in diabetic foot

    OpenAIRE

    Luís Jesuíno de Oliveira Andrade; Larissa Santos França; Paulo Roberto Santana de Melo; Marcelo Araújo

    2014-01-01

    Prescription of a drug outside of the indications for which it was originally approved by regulators is internationally known as "off-label" prescription. We describe off-label treatments for the diabetic foot reported in international scientific literature. This is a qualitative and descriptive bibliographical review based on the results of a search of the Medline international database. The criteria for review were publication between January 1985 and November 2013, and the MeSH (Medical Su...

  12. [Good prescription practice for out-patients-quality requirements of prescriptions in Germany].

    Science.gov (United States)

    Faller, Christine K; Seidling, Hanna M; Haefeli, Walter E

    2014-06-01

    Because the written prescription is a central communication medium between the prescribing physician and the dispensing pharmacist measures to improve the prescription quality are top priorities. While most primary care physicians in Germany use electronic systems, in outpatient clinics and nursing homes and on special occasions such as emergency services and home visits, many prescriptions are still handwritten. Incorrectly and illegibly issued prescriptions impair the physician-pharmacist-patient relationship and thus represent a risk factor in the context of medication safety. Well issued prescriptions expedite the dispensing and thus the continuity of treatment of the patients and spare human resources by avoiding queries and unnecessary steps in the care process. At the same time, legible and unequivocal prescriptions facilitate measures for quality assurance by the dispensing pharmacists and are essential preconditions needed for insurance reimbursement. Probably the most important step to high quality prescriptions is the consistent use of suitable electronic prescription software. This is only possible if physicians are willing to cooperate and understand the significance and benefits of an electronic prescription system.

  13. Impact of a Mandatory Prescription Drug Monitoring Program on Prescription of Opioid Analgesics by Dentists.

    Science.gov (United States)

    Rasubala, Linda; Pernapati, Lavanya; Velasquez, Ximena; Burk, James; Ren, Yan-Fang

    2015-01-01

    Prescription Drug Monitoring Programs (PDMP) are statewide databases that collect data on prescription of controlled substances. New York State mandates prescribers to consult the PDMP registry before prescribing a controlled substance such as opioid analgesics. The effect of mandatory PDMP on opioid drug prescriptions by dentists is not known. This study investigates the impact of mandatory PDMP on frequency and quantity of opioid prescriptions by dentists in a dental urgent care center. Based on the sample size estimate, we collected patient records of a 3-month period before and two consecutive 3-month periods after the mandatory PDMP implementation and analyzed the data on number of visits, treatment types and drug prescriptions using Chi-square tests. For patients who were prescribed pain medications, 452 (30.6%), 190 (14.1%), and 140 (9.6%) received opioid analgesics in the three study periods respectively, signifying a statistically significant reduction in the number of opioid prescriptions after implementation of the mandatory PDMP (pPrescriptions for non-opioid analgesics acetaminophen increased during the same periods (pprescription pattern for pain medications by dentists. Such change in prescription pattern represents a shift towards the evidence-based prescription practices for acute postoperative pain.

  14. Mexican plants and human fertility.

    Science.gov (United States)

    Crabbe, P

    1979-07-01

    Synthetic steroids are obtainable cheaply and in abundance from sapogenins, substances originating from plants of the Discorea family. Some 40 years ago, Russell Marker, an American chemist, discovered this source, which grows abundantly in Mexican jungles and is now exploited and cultivated commercially. Today synthetic steroids prepared from extracts from a wide range of vegetable sources are used in the treatment of rheumatoid arthritis, allergies, inflammatory diseases, sterility, and various heart conditions, and form the basis of modern oral contraceptives. Nevertheless, oral contraceptives in current use are still fairly costly, and women have to be educated in their use. What is needed urgently is a cheaper contraceptive pill with a long-term effect, and research is continuing. For example, scientists from the People's Republic of China have reported significant anti-fertility effects associated with 2 substances, anordin and dinordin, prepared with steroids derived from the sisal plants Agave sisilana and Agave americana. These agents, whose anti-fertility properties have been confirmed by scientists in Sweden and the United States, constitute a new family of contraceptives with the great advantage of having to be taken only once or twice instead of 20 times per month necessary with the ordinary pill. Also from China, scientists have reported the effectiveness of gossypol as an orally administered male contraceptive, although gossypol is not a steroid. It may become, however, a leading candidate for a male contraceptive.

  15. SEWAGE SLUDGE AS AN INGREDIENT IN FERTILIZERS AND SOIL SUBSTITUTES

    Directory of Open Access Journals (Sweden)

    Anna Grobelak

    2016-06-01

    Full Text Available In Poland, sludge management especially in medium and small sewage treatment plants is still a significant problem. According to data from the Central Statistical Office and the report on the implementation of the National Urban Wastewater Treatment Program (in polish KPOŚK land application of sewage sludge remains one of the main methods, although there has been considerable interest known: 'application for other purposes ", where the preparation of composts and fertilizers is included. The use of fertilizer produced from sewage sludge (compost, granules, organic and mineral fertilizers, is regulated by the Act on fertilizers and fertilization, and the relevant implementing rules. For example, they define the test procedure (concerning the quality of fertilizers to enable appropriate permissions to market this type of fertilizers. There is still only several technologies existing on the Polish market dedicated to production of fertilizers in advanced technologies of sewage sludge treatment. Usually the treatment plants are trying to obtain the necessary certificates for generated fertilizers (including composts, or soils substitutes. The advantages of these technologies should be no doubt: the loss of waste status, ability to store the fertilizer and unlimited transportation between areas, sanitization of the product (as a result of the use of calcium or sulfur compounds or temperature should be an alternative for drying technology. While the disadvantages are primarily the investment costs and time consuming certification procedures. However, these solutions enable to maintain the organic matter and phosphorus as well as greater control over possible pollution introduced into the soil.

  16. Chitosan-Montmorillonite microspheres: A sustainable fertilizer delivery system.

    Science.gov (United States)

    dos Santos, Bruna Rodrigues; Bacalhau, Fabiana Britti; Pereira, Tamires dos Santos; Souza, Claudinei Fonseca; Faez, Roselena

    2015-08-20

    Controlled release fertilizers are efficient tools that increase the sustainability of agricultural practices. However, the biodegradability of the matrices and the determination of the release into soil still require some investigation. This paper describes the preparation of potassium-containing microspheres based on chitosan and montmorillonite clay and the in situ soil release. The chitosan-montmorillonite microspheres were prepared using a coagulation method and different proportions of montmorillonite. The structural, thermal and morphological properties as well the water swelling and fertilizer sorption capacity were evaluated. The best formulations were applied in soil, and the fertilizer release was monitored using time-domain reflectometry (TDR). Montmorillonite clay provides better sorption properties than the chitosan microspheres because of the rough and porous surface. Due to these properties, high levels of fertilizer were sorbed onto the material. ChMMT33-containing potassium shows two specific periods of fertilizer release: the first one lasted approximately three days and was assigned to the external fertilizer on the microspheres. The second was assigned to the internal fertilizer. TDR is an important and fast tool and was used to determine the fertilizer release and the ion movement in the soil.

  17. Optimizing Natural Fertility

    Science.gov (United States)

    ... heavy alcohol consumption (> 2 drinks per day), heavy caffeine consumption, and the use of recreational drugs such as marijuana have all been associated with reduced fertility. Therefore, women (and ... alcohol and caffeine use, and avoid smoking and all recreational drugs ...

  18. Commercial Nitrogen Fertilizer Purchased

    Data.gov (United States)

    U.S. Environmental Protection Agency — Amounts of fertilizer nitrogen (N) purchased by states in individual years 2003, 2005, 2007, 2009 and 2011, and the % change in average amounts purchased per year...

  19. Chapter VII. Predicting Fertility

    Science.gov (United States)

    Section 2. Visual and Microscopic Approaches for Differentiating Unfertilized Germinal Discs and Early dead Embryos from Pre-Incubated Blastoderms Section 3. Predicting the Duration of fertility by Counting Sperm in the Outer Perivitelline Layer of Laid Eggs...

  20. Cancer and fertility preservation

    DEFF Research Database (Denmark)

    Lambertini, Matteo; Del Mastro, Lucia; Pescio, Maria C

    2016-01-01

    cryopreservation and embryo/oocyte cryopreservation are standard strategies for fertility preservations in male and female patients, respectively; other strategies (e.g. pharmacological protection of the gonads and gonadal tissue cryopreservation) are considered experimental techniques. However, since then, new......In the last years, thanks to the improvement in the prognosis of cancer patients, a growing attention has been given to the fertility issues. International guidelines on fertility preservation in cancer patients recommend that physicians discuss, as early as possible, with all patients...... of reproductive age their risk of infertility from the disease and/or treatment and their interest in having children after cancer, and help with informed fertility preservation decisions. As recommended by the American Society of Clinical Oncology and the European Society for Medical Oncology, sperm...

  1. Commercial Phosporus Fertilizer Purchased

    Data.gov (United States)

    U.S. Environmental Protection Agency — Amounts of fertilizer P2O5 purchased by states in individual years 2003, 2005, 2007, 2009 and 2011, and the % change in average amounts purchased per year from...

  2. Off-label prescription of drugs at hospital

    Directory of Open Access Journals (Sweden)

    Vicente Arocas Casañ

    2016-03-01

    Full Text Available Objectives: To develop a procedure for management of off-label medications, and to analyze the treatments, indications, and hospital units which will request them more frequently, as well as which variables will have an impact on the authorization decision, and its economic impact. Methods: A procedure was designed where clinicians would complete request forms and the Hospital Unit would prepare reports assessing their efficacy, safety, convenience, and cost. The request forms for the past five years were analyzed. Results: A total of 834 applications were received, and 88.1% of these were accepted. The authorization rates were higher for Paediatric Units (95.7% vs. 86.6%; p<0.05. The reasons for considering prescriptions as off-label were: different indication (73.2%, different combination (10.2%, different line of treatment (8.6% and different age (8%. A 73.4% of requests were for antineoplastic drugs, and the most frequently prescribed were rituximab (120 and bevacizumab (103. The quality of evidence supporting the prescriptions was moderate-low, though no direct relationship with the likelihood of approval was demonstrated (p = 0.413. The cost of the approved medications was 8,567,537 €, and the theoretical savings for those drugs rejected was of 2,268,642 €. There was a statistically significant decrease in the authorization rate (p < 0.05, Student’s t test when spending increased. Conclusions: The responsibility for assessing off-label prescriptions has fallen on the Pharmacy Unit. It has not been demonstrated that the quality of evidence represents a decisive variable for approval of treatment; on the other hand, age and cost have demonstrated a significant impact

  3. Antibiotic Prescription in Danish General Practice

    DEFF Research Database (Denmark)

    Sydenham, Rikke Vognbjerg; Plejdrup Hansen, Malene; Pedersen, Line Bjørnskov

    2016-01-01

    will explore how the GPs prescription behaviour is influenced by selected factors. Antibiotics are essential when treating potentially lethal infections. An increasing development of resistant bacteria is considered one of the primary threats to public health. The majority of antibiotics (90%) are prescribed...... from general practice. The prescription of broad-spectrum antibiotics can cause unnecessary side effects for the individual and increases the risk of development of bacteria resistant to antibiotic treatment. Both the prescription of broad-spectrum antibiotics and the level of resistant bacteria......1. Background & Aim The overall aim of the project is to describe antibiotic consumption in Danish general practice with emphasis on specific types of antibiotics. The project will shed light on the impact of microbiological diagnostic methods (MDM) on the choice of antibiotic and the project...

  4. [Failure modes and effects analysis in the prescription, validation and dispensing process].

    Science.gov (United States)

    Delgado Silveira, E; Alvarez Díaz, A; Pérez Menéndez-Conde, C; Serna Pérez, J; Rodríguez Sagrado, M A; Bermejo Vicedo, T

    2012-01-01

    To apply a failure modes and effects analysis to the prescription, validation and dispensing process for hospitalised patients. A work group analysed all of the stages included in the process from prescription to dispensing, identifying the most critical errors and establishing potential failure modes which could produce a mistake. The possible causes, their potential effects, and the existing control systems were analysed to try and stop them from developing. The Hazard Score was calculated, choosing those that were ≥ 8, and a Severity Index = 4 was selected independently of the hazard Score value. Corrective measures and an implementation plan were proposed. A flow diagram that describes the whole process was obtained. A risk analysis was conducted of the chosen critical points, indicating: failure mode, cause, effect, severity, probability, Hazard Score, suggested preventative measure and strategy to achieve so. Failure modes chosen: Prescription on the nurse's form; progress or treatment order (paper); Prescription to incorrect patient; Transcription error by nursing staff and pharmacist; Error preparing the trolley. By applying a failure modes and effects analysis to the prescription, validation and dispensing process, we have been able to identify critical aspects, the stages in which errors may occur and the causes. It has allowed us to analyse the effects on the safety of the process, and establish measures to prevent or reduce them. Copyright © 2010 SEFH. Published by Elsevier Espana. All rights reserved.

  5. Impact of patient-based teaching in improving prescription writing skills of II MBBS students.

    Science.gov (United States)

    Thenrajan, Padmavathi; Murugan, P Rajavel

    2016-01-01

    Although prescription writing is a part of the medical students' curriculum, their prescribing skills are still poor either as a part of their examinations or as they go out as qualified health professionals which may be due to inadequate training. Educational intervention like patient-based teaching in pharmacology offers lifelike preparation and provides more relevance, easier recall, and help in improving prescribing skills. This study aims to determine the role of patient-based teaching in improving the prescribing skill of II year medical students compared to conventional case-based teaching. This prospective, comparative study was carried out after giving orientation to prescription writing as per the WHO prescribing guidelines (N = 50). The 25 students in control group were given case-based teaching and 25 students in test group were given patient-based teaching of prescription writing for the same five common clinical conditions. The prescription writing skill (knows how level) was assessed by evaluating the prescriptions written in the prescribed format and scored by a 14-point scoring system. The mean scores obtained by the control (9.6) and test (12.04) groups were compared by unpaired Student's t-test (P writing enables students to develop prescribing skills in a complete and professional way.

  6. GIS Modelling for Site-Specific Nitrogen Fertilization towards Soil Sustainability

    Directory of Open Access Journals (Sweden)

    Antonis Papadopoulos

    2015-05-01

    Full Text Available Farmers need to make decisions that in most cases incorporate the concept of prediction and can hardly be revoked. One such decision is the application of fertilizing inputs. During past crop management and decision-making on fertilizing practices, many significant errors have been recorded, which have led and continue to lead to reduced production and environmental burden. The methodology followed in this paper involves the use of GIS, fuzzy logic and expert knowledge, in order to model physical processes associated with nitrogen balance in cultivated ecosystems and to evaluate the capabilities of or limitations on the use of certain fertilizers, based on spatial criteria. An original spatial decision support system was designed, developed and applied in a given study area. The system is composed of two modules (“fertilizing rate” and “fertilizing type”, making use of soil, climate and cultivation practices’ data, as recorded in the area of interest in quantitative or categorical form. The results of the application spatially classify the involved area according to its demand for nitrogen on the basis of the characteristics of each sub-region. The “fertilizing rate” module suggests reduced fertilizing doses of nitrogenous fertilizers compared to those already applied in the area. The system further divides the area into zones where specific types of fertilizers should be applied, giving a certain prescription for the method and time of application.

  7. 蚯蚓粪有机肥的制备及其对不同蔬菜产量和抗病性的影响%Preparation of Wormcast Organic Fertilizer and Its Effects on Yield and Disease Resistance of Different Vegetables

    Institute of Scientific and Technical Information of China (English)

    魏晓明

    2015-01-01

    为更好地利用蚯蚓粪,制备了一种新型蚯蚓粪有机肥,并研究了其在大棚栽培条件下对不同蔬菜产量和病害的影响。研究结果表明,蚯蚓粪有机肥的制备操作简单,容易掌握,适合规模化生产及推广,其价格低廉,环境友好,能显著提高蔬菜的产量和抗病性,适于在有机蔬菜基地使用,既能节约成本,又能增加经济效益,有利于环境保护和农业的可持续发展。%To make a better use of wormcast, we prepared a new-type worm cast organic fertilizer and studied its effects on yield and disease resistance of greenhouse vegetables. The results showed that, the way to prepare wormcast organic fertilizer was quite easy and it was not hard for people to master, thus it was suitable for scale production and popularization. As a cheap but environmental-friendly organic fertilizer, it could remarkably improve yield and disease resistance of vegetables. And it was suitable to be used in organic vegetable base, which not only saved cost but also helped to increase economic benefit, so, it was benefical to protect environment and promote sustainable development of agriculture.

  8. Slim accretion discs with different viscosity prescriptions

    Energy Technology Data Exchange (ETDEWEB)

    Szuszkiewicz, E. (Max-Planck-Institut fuer Physik und Astrophysik, Garching (Germany, F.R.). Inst. fuer Astrophysik)

    1990-05-15

    The variability of X-ray sources powered by accretion may be connected to thermal instabilities in the innermost parts of slim discs. The time-scales of variability predicted by the theory with the standard {alpha}-viscosity prescription agree with those observed in a wide range of sources. The amplitudes (3-4 orders of magnitude in luminosity) are correctly predicted for X-ray transient sources, but in general are too big for quasars, Seyferts, galactic black hole candidates and LMXBs. We show here that a slight modification of the viscosity prescription can offer a much better agreement with observations. (author).

  9. The law on electronic medical prescriptions

    Directory of Open Access Journals (Sweden)

    Francis de Clippele

    2005-01-01

    Full Text Available Health care is one of the most important economic and business areas. The European Union has therefore worked out an e-health care strategy to achieving stronger growth and increased effectiviness of services. The application of information and communications technologies (ICT that affect the health care sector, is developing fast in Europe. In this respect various countries have launched pilot projects in order to modernize their medical prescription practices. A model of the electronic medical prescription must respect patient's rights and can only be deployed in a system of security in order to protect the confidentiality.

  10. On prescription-syndrome correspondence of classic prescriptions%认识经方方证

    Institute of Scientific and Technical Information of China (English)

    冯世纶

    2013-01-01

    This paper presents some considerations on prescription-syndrome correspondence of classic prescription.Prescription-syndrome is the basic structure of Treatise on Febrile and Miscellaneous Disease and originates from Shennong era.The accumulation of application experience of prescription-syndrome produces six meridian differentiation.What' s more, the theoretical basis of prescription correspondence to syndrome is eight principal syndromes, and prescription correspondence to syndrome includes the correspondence of prescription and syndrome, herb dosage and disorder severity, decoction-administration methods and disease condition.%介绍对经方方证的几点认识.认为方证是《伤寒杂病论》的基本构成,其形成起源于神农时代,方证应用经验的积累促使六经辨证的产生;方证相应的基础理论是八纲,方证是辨证的尖端,方证相应包括方与证对应、药量与病情对应、煎服法与病情对应.

  11. Mystery Written on Prescription Pads: Exploring Marketing Factors Influencing Prescription Behaviour using the AHP Approach

    Directory of Open Access Journals (Sweden)

    Hemant Bamoriya

    2012-12-01

    Full Text Available The Indian Pharma market is highly fragmented & nature of competition is intense. Further, in modern times influencing doctors’ prescription decision has become very complex as there is little systematic knowledge about factors affecting the doctors’ prescription behaviour and the weight of individual factor. This study aims to demystify this complex prescription behaviour of doctors, through examining the above mentioned factors. For this purpose, a focus group study will be followed by a quantitative study using the Analytic Hierarchy Process (AHP approach. The findings of the study will have important implications for the marketers in order to do proper allocation of their resources, to improve their promotional efficiency.

  12. Linguistic Prescription: Familiar Practices and New Perspectives.

    Science.gov (United States)

    Finegan, Edward

    2003-01-01

    Reports on a question by a law student of whether a correction of "sneaked" to "snuck" suggests misinformation and misguided rigidity in the context of better information about current legal usage and a perennial tendency to linguistic prescription. Explores attitudes to current borrowings from English into Japanese and French and distinguishes…

  13. 76 FR 51310 - Branded Prescription Drug Fee

    Science.gov (United States)

    2011-08-18

    ... Act (ACA). The regulations affect persons engaged in the business of manufacturing or importing... Clearance Officer, SE:W:CAR:MP:T:T:SP, Washington, DC 20224. Comments on the collection of information... business of manufacturing or importing branded prescription drugs by section 9008 of the ACA. The text of...

  14. An Expert System for Designing Fire Prescriptions

    Science.gov (United States)

    Elizabeth Reinhardt

    1987-01-01

    Managers use prescribed fire to accomplish a variety of resource objectives. The knowledge needed to design successful prescriptions is both quantitative and qualitative. Some of it is available through publications and computer programs, but much of the knowledge of expert practitioners has never been collected or published. An expert system being developed at the,...

  15. The Prescription Opioid Pain Medication Overdose Epidemic

    Centers for Disease Control (CDC) Podcasts

    2016-04-19

    Overdose related to prescription opioids has become an epidemic. This podcast discusses the risks of this type of drug sometimes used to treat pain, and how to protect yourself. .  Created: 4/19/2016 by National Center for Chronic Disease Prevention and Health Promotion (NCCDPHP).   Date Released: 4/19/2016.

  16. Respiratory infection and antibiotic prescription rates.

    NARCIS (Netherlands)

    Otters, H.; Wouden, J. van der; Schellevis, F.

    2004-01-01

    In the October issue of the BJGP, Fleming et al showed that a decrease in antibiotic prescription rates is directly related to a decrease in respiratory infections presented in general practice. We compliment the authors for their interesting study and the clear presentation of their results.

  17. Prescriptions Guiding Prospective Teachers in Teaching Mathematics

    Science.gov (United States)

    Zembat, Ismail Özgür; Aslan, Mustafa

    2016-01-01

    This study aims to investigate the nature of different mathematics teaching modes (prescriptions) that guide prospective teachers during their instruction. The participants were 24 junior prospective middle school mathematics teachers (19 females and 5 males) who were attending a mathematics methods course at a private university in central…

  18. COLOR PRESCRIPTION FORM FOR COSMETIC GLOVES

    Science.gov (United States)

    A technique is described for achieving more custom-like coloring of cosmetic gloves. The method involves the use of a color prescription form which...can be used to describe in greater detail the characteristics of those portions of the human hand of greater cosmetic significance.

  19. Closing the Prescription Drug Coverage Gap

    Science.gov (United States)

    ... drugs they make are covered during the coverage gap for that calendar year. This includes prescription drugs on the plan’s formulary ( ... you pay for generic drugs during the coverage gap will decrease each year until it reaches 25% in 2020. The coverage ...

  20. New patient asking for a benzodiazepine prescription

    Institute of Scientific and Technical Information of China (English)

    Simon de Lusignan; Andy Kent

    2008-01-01

    @@ Your final patient on a Friday is a 26 year old man who is new to the list. He asks you for a repeat prescription for two months of diazepam, 5 mg up to four a day. He says he has been taking these for a whil for his "newves" and he has run out. You do not hold this patient's records.

  1. Fertility outcomes in asthma

    DEFF Research Database (Denmark)

    Gade, Elisabeth Juul; Thomsen, Simon Francis; Lindenberg, Svend

    2016-01-01

    Evidence is increasing of an association between asthma and aspects of female reproduction. However, current knowledge is limited and furthermore relies on questionnaire studies or small populations. In a prospective observational cohort study to investigate whether time to pregnancy, the number...... of fertility treatments, and the number of successful pregnancies differ significantly between women with unexplained infertility with and without asthma.245 women with unexplained infertility (aged 23-45 years) underwent questionnaires and asthma and allergy testing while undergoing fertility treatment. 96...... women entering the study had either a former doctor's diagnosis of asthma or were diagnosed with asthma when included. After inclusion they were followed for a minimum of 12 months in fertility treatment, until they had a successful pregnancy, stopped treatment, or the observation ended.The likelihood...

  2. Sotho fertility symbolism.

    Science.gov (United States)

    Murray, C

    1980-01-01

    This paper deals with the traditional beliefs and mythical folklore of the Sotho-Tswana ethnic tribes of South Africa. Their ritual practices are predominantly concerned with the weather, the vicissitudes of the seasonal cycle, and, especially the rain-making powers of certain individuals. It is well known that rain, in all civilizations, is a symbol of fertility. Thus, adolescent girls and young women, as mediators of the association between water and fertility, can be relied upon to bring the clouds and torrential downpours. The characteristic Sesotho explanation that babies come from the river is clearly an allusion to the water of the womb, and the river is generally recognized as a methaphor of the womb. Also, the onset of menarche involves rituals having to do with the drawing and pouring of water, another clear allusion to the beginning of fertility.

  3. Half of Opioid Prescriptions Go to People with Mental Illness

    Science.gov (United States)

    ... medlineplus.gov/news/fullstory_167031.html Half of Opioid Prescriptions Go to People With Mental Illness Those ... disorders receive a troubling percentage of the nation's opioid prescriptions, a new study finds. Of the 115 ...

  4. U.S. Opioid Prescriptions Fall, But Numbers Still High

    Science.gov (United States)

    ... https://medlineplus.gov/news/fullstory_167050.html U.S. Opioid Prescriptions Fall, But Numbers Still High: CDC And ... THURSDAY, July 6, 2017 (HealthDay News) -- Prescriptions for opioid painkillers have dropped since 2010 in the United ...

  5. Prescription patterns and treatment outcomes of hypertension in ...

    African Journals Online (AJOL)

    Prescription patterns and treatment outcomes of hypertension in urban hospitals of Jos, Plateau State. ... Nigerian Journal of Pharmaceutical Research ... Results of this study revealed several rational and non-rational prescription practices in ...

  6. Abuse of Prescription (Rx) Drugs Affects Young Adults Most

    Science.gov (United States)

    ... Affects Young Adults Most Abuse of Prescription (Rx) Drugs Affects Young Adults Most Email Facebook Twitter Text Description of Infographic Young adults (age 18 to 25) are the biggest abusers of prescription (Rx) opioid pain relievers, ADHD stimulants, ...

  7. Prescription patterns of general practitioners in peshawar, pakistan

    National Research Council Canada - National Science Library

    Raza, Usman Ahmad; Khursheed, Tayyeba; Irfan, Muhammad; Abbas, Maryam; Irfan, Uma Maheswari

    2014-01-01

    To find out prescription patterns of general practitioners in Peshawar. Cross-sectional survey of drug prescriptions was done at six major hospitals and pharmacies of Peshawar between April and May 2011...

  8. Strategies Used by Adults to Reduce Their Prescription Drug Costs

    Science.gov (United States)

    ... Order from the National Technical Information Service NCHS Strategies Used by Adults to Reduce Their Prescription Drug ... Interview Survey, alternative therapies, medication Adults used several strategies to reduce prescription drug costs. Figure 1. Percentages ...

  9. Prescription Drug Plan Formulary, Pharmacy Network, and P...

    Data.gov (United States)

    U.S. Department of Health & Human Services — These public use files contain formulary, pharmacy network, and pricing data for Medicare Prescription Drug Plans and Medicare Advantage Prescription Drug Plans...

  10. 76 FR 17137 - Pregnancy and Prescription Medication Use Symposium

    Science.gov (United States)

    2011-03-28

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration Pregnancy and Prescription Medication Use Symposium AGENCY... announcing the following meeting: Pregnancy and Prescription Medication Use Symposium. The topic to...

  11. Potentially inappropriate prescriptions in patients admitted to a psychiatric hospital

    DEFF Research Database (Denmark)

    Soerensen, Ann Lykkegaard; Nielsen, Lars Peter; Poulsen, Birgitte Klindt

    2016-01-01

    the most frequent PIP. Predictive factors for PIP were polypharmacy (>5 prescriptions) and having one or more somatic diagnoses. Conclusion PIP is common in psychiatric patients and potentially fatal. Particularly polypharmacy (>5 prescriptions) and concomitant somatic illness were associated...

  12. Fertility incentives and disincentives.

    Science.gov (United States)

    Financioglu, N

    1984-06-01

    Some 40 countries use some form of incentives and disincentives in support of population policies, about half with the aim of reducing fertility and half with the aim of increasing it. These schemes range from limitations on tax and family allowances or maternity benefits after a given family size has been reached to payments to acceptors of fertility control methods. Some schemes aim to eliminate or reduce the cost and inconvenience people may face in achieving their fertility preferences, whereas others contain an element of deterrence. It is difficult to isolate and measure the impact of incentives on fertility from the effects of other factors such as family planning service availability or modernization. Studies in pronatalist countries suggest that incentive schemes produce short-term fertility increases without a change in average family size. Monetary incentives must be constantly increased to keep pace with inflation, placing a heavy burden on government budgets. Administrative capacity to operate the scheme is critical in terms of both manpower and efficient systems for record keeping, monitoring, and close supervision to prevent abuse. There is also considerable debate on the moral and ethical implications of incentives and disincentives as policy tools. Incentives offered for the acceptance of a particular fertility control method potentially contravene the principle of voluntary and informed consent. In addition, the relative value of the reward is greater for those in the lower income groups. The discriminatory nature of certain types of incentives and disincentives is illustrated by measures introduced in Singapore that give highest priority in school enrollment to the children of highly educated mothers with 2-3 children. This ruling is expected to further intensify the controversy surrounding incentive and disincentive schemes.

  13. Adolescent fertility: worldwide concerns.

    Science.gov (United States)

    Senderowitz, J; Paxman, J M

    1985-04-01

    There is growing concern over the adverse health, social, economic, and demographic effects of adolescent fertility. Morbidity and mortality rates ar significantly higher for teenage mothers and their infants, and early initiation of childbearing generally means truncated education, lower future family income, and larger completed family size. Adolescent fertility rates, which largely reflect marriage patterns, range from 4/1000 in Mauritania; in sub-Saharan Africa, virtually all rates are over 100. In most countries, adolescent fertility rates are declining due to rising age at marriage, increased educational and economic opportunities for young women, changes in social customs, increased use of contraception, and access to abortion. However, even if fertility rates were to decline dramatically among adolescent women in developing countries, their sheer numbers imply that their fertility will have a major impact on world population growth in the years ahead. The number of women in the world ages 15-19 years is expected to increase from 245 million in 1985 to over 320 million in the years 2020; 82% of these women live in developing countries. As a result of more and earlier premarital sexual activity, fostered by the lengthening gap between puberty and marriage, diminished parental and social controls, and increasing peer and media pressure to be sexually active, abortion and out-of-wedlock childbearing are increasing among teenagers in many developed and rapidly urbanizing developing countries. Laws and policies regarding sex education in the schools and access to family planning services by adolescents can either inhibit or support efforts to reduce adolescent fertility. Since contraceptive use is often sporadic and ineffective among adolescents, family planning services are crucial. Such programs should aim to reduce adolescents' dependence on abortion through preventive measures and increase awareness of the benefits of delayed sexual activity. Similarly, sex

  14. Prescription, dispensation and marketing patterns of methylphenidate

    Science.gov (United States)

    Perini, Edson; Junqueira, Daniela Rezende Garcia; Lana, Lorena Gomes Cunha; Luz, Tatiana Chama Borges

    2014-01-01

    OBJECTIVE To analyze the patterns and legal requirements of methylphenidate consumption. METHODS We conducted a cross-sectional study of the data from prescription notification forms and balance lists of drugs sales – psychoactive and others – subject to special control in the fifth largest city of Brazil, in 2006. We determined the defined and prescribed daily doses, the average prescription and dispensation periods, and the regional sales distribution in the municipality. In addition, we estimated the costs of drug acquisition and analyzed the individual drug consumption profile using the Lorenz curve. RESULTS The balance lists data covered all notified sales of the drug while data from prescription notification forms covered 50.6% of the pharmacies that sold it, including those with the highest sales volumes. Total methylphenidate consumption was 0.37 DDD/1,000 inhabitants/day. Sales were concentrated in more developed areas, and regular-release tablets were the most commonly prescribed pharmaceutical formulation. In some regions of the city, approximately 20.0% of the prescriptions and dispensation exceeded 30 mg/day and 30 days of treatment. CONCLUSIONS Methylphenidate was widely consumed in the municipality and mainly in the most developed areas. Of note, the consumption of formulations with the higher abuse risk was the most predominant. Both its prescription and dispensation contrasted with current pharmacotherapeutic recommendations and legal requirements. Therefore, the commercialization of methylphenidate should be monitored more closely, and its use in the treatment of behavioral changes of psychological disorders needs to be discussed in detail, in line with the concepts of the quality use of medicines. PMID:26039389

  15. Prescription, dispensation and marketing patterns of methylphenidate.

    Science.gov (United States)

    Perini, Edson; Junqueira, Daniela Rezende Garcia; Lana, Lorena Gomes Cunha; Luz, Tatiana Chama Borges

    2014-12-01

    OBJECTIVE To analyze the patterns and legal requirements of methylphenidate consumption. METHODS We conducted a cross-sectional study of the data from prescription notification forms and balance lists of drugs sales - psychoactive and others - subject to special control in the fifth largest city of Brazil, in 2006. We determined the defined and prescribed daily doses, the average prescription and dispensation periods, and the regional sales distribution in the municipality. In addition, we estimated the costs of drug acquisition and analyzed the individual drug consumption profile using the Lorenz curve. RESULTS The balance lists data covered all notified sales of the drug while data from prescription notification forms covered 50.6% of the pharmacies that sold it, including those with the highest sales volumes. Total methylphenidate consumption was 0.37 DDD/1,000 inhabitants/day. Sales were concentrated in more developed areas, and regular-release tablets were the most commonly prescribed pharmaceutical formulation. In some regions of the city, approximately 20.0% of the prescriptions and dispensation exceeded 30 mg/day and 30 days of treatment. CONCLUSIONS Methylphenidate was widely consumed in the municipality and mainly in the most developed areas. Of note, the consumption of formulations with the higher abuse risk was the most predominant. Both its prescription and dispensation contrasted with current pharmacotherapeutic recommendations and legal requirements. Therefore, the commercialization of methylphenidate should be monitored more closely, and its use in the treatment of behavioral changes of psychological disorders needs to be discussed in detail, in line with the concepts of the quality use of medicines.

  16. Literacy and misunderstanding prescription drug labels.

    Science.gov (United States)

    Davis, Terry C; Wolf, Michael S; Bass, Pat F; Thompson, Jason A; Tilson, Hugh H; Neuberger, Marolee; Parker, Ruth M

    2006-12-19

    Health literacy has increasingly been viewed as a patient safety issue and may contribute to medication errors. To examine patients' abilities to understand and demonstrate instructions found on container labels of common prescription medications. Cross-sectional study using in-person, structured interviews. 3 primary care clinics serving mostly indigent populations in Shreveport, Louisiana; Jackson, Michigan; and Chicago, Illinois. 395 English-speaking adults waiting to see their providers. Correct understanding of instructions on 5 container labels; demonstration of 1 label's dosage instructions. Correct understanding of the 5 labels ranged from 67.1% to 91.1%. Patients reading at or below the sixth-grade level (low literacy) were less able to understand all 5 label instructions. Although 70.7% of patients with low literacy correctly stated the instructions, "Take two tablets by mouth twice daily," only 34.7% could demonstrate the number of pills to be taken daily. After potential confounding variables were controlled for, low (adjusted relative risk, 2.32 [95% CI, 1.26 to 4.28]) and marginal (adjusted relative risk, 1.94 [CI, 1.14 to 3.27]) literacy were significantly associated with misunderstanding. Taking a greater number of prescription medications was also statistically significantly associated with misunderstanding (adjusted relative risk, 2.98 [CI, 1.40 to 6.34] for > or =5 medications). The study sample was at high risk for poor health literacy and outcomes. Most participants were women, and all spoke English. The authors did not examine the association between misunderstanding and medication error or evaluate patients' actual prescription drug-taking behaviors. Lower literacy and a greater number of prescription medications were independently associated with misunderstanding the instructions on prescription medication labels.

  17. Prescription, dispensation and marketing patterns of methylphenidate

    Directory of Open Access Journals (Sweden)

    Edson Perini

    2014-12-01

    Full Text Available OBJECTIVE To analyze the patterns and legal requirements of methylphenidate consumption. METHODS We conducted a cross-sectional study of the data from prescription notification forms and balance lists of drugs sales – psychoactive and others – subject to special control in the fifth largest city of Brazil, in 2006. We determined the defined and prescribed daily doses, the average prescription and dispensation periods, and the regional sales distribution in the municipality. In addition, we estimated the costs of drug acquisition and analyzed the individual drug consumption profile using the Lorenz curve. RESULTS The balance lists data covered all notified sales of the drug while data from prescription notification forms covered 50.6% of the pharmacies that sold it, including those with the highest sales volumes. Total methylphenidate consumption was 0.37 DDD/1,000 inhabitants/day. Sales were concentrated in more developed areas, and regular-release tablets were the most commonly prescribed pharmaceutical formulation. In some regions of the city, approximately 20.0% of the prescriptions and dispensation exceeded 30 mg/day and 30 days of treatment. CONCLUSIONS Methylphenidate was widely consumed in the municipality and mainly in the most developed areas. Of note, the consumption of formulations with the higher abuse risk was the most predominant. Both its prescription and dispensation contrasted with current pharmacotherapeutic recommendations and legal requirements. Therefore, the commercialization of methylphenidate should be monitored more closely, and its use in the treatment of behavioral changes of psychological disorders needs to be discussed in detail, in line with the concepts of the quality use of medicines.

  18. Fertility and the economy.

    Science.gov (United States)

    Becker, G S

    1992-08-01

    Fertility and the economy is examined in the context of the Malthusian question about the links between family choices and longterm economic growth. Micro level differences are not included not are a comprehensive range of economic or determinant variables. Specific attention is paid to income and price effects, the quality of children, overlapping generations, mortality effects, uncertainty, and economic growth. Fertility and the demand for children in linked to parental incomes and the cost of rearing children, which is affected by public policies that change the costs. Demand is also related to child and adult mortality, and uncertainty about sex of the child. Fertility in one generation affects fertility in the next. Malthusian and neoclassical models do not capture the current model of modern economies with rising income/capita and human and physical capital, extensive involvement of married women in the labor force, and declining fertility to very low levels. In spite of the present advances in firm knowledge about the relationships between fertility and economic and social variables, there is still much greater ignorance of the interactions. The Malthusian utility function that says fertility rises and falls with income did hold up to 2 centuries of scrutiny, and the Malthusian inclusion of the shifting tastes in his analysis could be translated in the modern context to include price of children. The inclusion of net cost has significant consequences, i.e., rural fertility can be higher because the cost of rearing when children contribute work to maintaining the farm is lower than in the city. An income tax deduction for children in the US reduces cost. Economic growth raises the cost of children due the time spent on child care becoming more valuable. The modern context has changed from Malthusian time, and the cost of education, training, and medical care is relevant. The implication is that a rise in income could reduce the demand for children when

  19. Exercise on Prescription: trial protocol and evaluation of outcomes

    OpenAIRE

    Puggaard Lis; Kjær Kirsten; Kragstrup Jakob; Sørensen Jes B

    2007-01-01

    Abstract Background In many countries exercise prescriptions are used in an attempt to initiate a physically active lifestyle in sedentary populations. Previous studies have primarily evaluated low intensive exercise prescription interventions and found moderately positive effects on physical activity and aerobic fitness. In a highly intensive Danish exercise prescription scheme called 'Exercise on Prescription' (EoP) the general practitioners can prescribe EoP to sedentary patients with life...

  20. Soil microbes and plant fertilization.

    Science.gov (United States)

    Miransari, Mohammad

    2011-12-01

    With respect to the adverse effects of chemical fertilization on the environment and their related expenses, especially when overused, alternative methods of fertilization have been suggested and tested. For example, the combined use of chemical fertilization with organic fertilization and/or biological fertilization is among such methods. It has been indicated that the use of organic fertilization with chemical fertilization is a suitable method of providing crop plants with adequate amount of nutrients, while environmentally and economically appropriate. In this article, the importance of soil microbes to the ecosystem is reviewed, with particular emphasis on the role of plant growth-promoting rhizobacteria, arbuscular mycorrhizal fungi, and endophytic bacteria in providing necessary nutrients for plant growth and yield production. Such microbes are beneficial to plant growth through colonizing plant roots and inducing mechanisms by which plant growth increases. Although there has been extensive research work regarding the use of microbes as a method of fertilizing plants, it is yet a question how the efficiency of such microbial fertilization to the plant can be determined and increased. In other words, how the right combination of chemical and biological fertilization can be determined. In this article, the most recent advances regarding the effects of microbial fertilization on plant growth and yield production in their combined use with chemical fertilization are reviewed. There are also some details related to the molecular mechanisms affecting the microbial performance and how the use of biological techniques may affect the efficiency of biological fertilization.

  1. 21 CFR 202.1 - Prescription-drug advertisements.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 4 2010-04-01 2010-04-01 false Prescription-drug advertisements. 202.1 Section...) DRUGS: GENERAL PRESCRIPTION DRUG ADVERTISING § 202.1 Prescription-drug advertisements. (a)(1) The... ingredients in the advertisement shall be the same as the order of listing of ingredients on the label of...

  2. The Philosophical Foundations of Prescriptive Statements and Statistical Inference

    Science.gov (United States)

    Sun, Shuyan; Pan, Wei

    2011-01-01

    From the perspectives of the philosophy of science and statistical inference, we discuss the challenges of making prescriptive statements in quantitative research articles. We first consider the prescriptive nature of educational research and argue that prescriptive statements are a necessity in educational research. The logic of deduction,…

  3. Resonant Messages to Prevent Prescription Drug Misuse by Teens

    Science.gov (United States)

    Twombly, Eric C.; Holtz, Kristen D.; Agnew, Christine B.

    2011-01-01

    Prescription drug misuse is a major health problem, particularly among teens. A key step in curbing misuse is the development of effective prescription drug prevention messages. This paper explores the elements of prescription drug misuse prevention messages that resonate with teens using data from focus groups with seventh and eighth grade…

  4. The Philosophical Foundations of Prescriptive Statements and Statistical Inference

    Science.gov (United States)

    Sun, Shuyan; Pan, Wei

    2011-01-01

    From the perspectives of the philosophy of science and statistical inference, we discuss the challenges of making prescriptive statements in quantitative research articles. We first consider the prescriptive nature of educational research and argue that prescriptive statements are a necessity in educational research. The logic of deduction,…

  5. 21 CFR 1306.09 - Prescription requirements for online pharmacies.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 9 2010-04-01 2010-04-01 false Prescription requirements for online pharmacies... PRESCRIPTIONS General Information § 1306.09 Prescription requirements for online pharmacies. (a) No controlled... constitutes dispensing by means of the Internet unless such person is a pharmacist who is acting in the...

  6. Patterns of Prescription Medication Diversion among Drug Dealers

    Science.gov (United States)

    Rigg, Khary K.; Kurtz, Steven P.; Surratt, Hilary L.

    2012-01-01

    This research examined the following questions: (1) how do drug dealers acquire their inventories of prescription medications? and (2) which types of prescription medications do dealers most commonly sell? Data are drawn from a National Institute on Drug Abuse-funded research study that examined prescription drug diversion and abuse in South…

  7. Prescriptions for adaptive comanagement: the case of flood management in the German Rhine basin

    Directory of Open Access Journals (Sweden)

    Gert Becker

    2015-09-01

    Full Text Available Centrally administered bureaucracies are ill suited to managing the environmental resources of complex social-ecological systems. Therefore management approaches are required that can better deal with its complexity and uncertainty, which are further exacerbated by developments such as climate change. Adaptive comanagement (ACM has emerged as a relatively novel governance approach and potential solution to the challenges arising. Adaptive comanagement hinges on certain institutional prescriptions intended to enhance the adaptability of management by improving the comprehension of and response to the complex context and surprises of social-ecological systems. The ACM literature describes that for enhanced adaptability, institutional arrangements should be polycentric, aligned with the scale of ecosystems (the bioregional approach, feature open and participatory governance, and involve much experimentation. The case of flood management in the German part of the Rhine basin is used to provide an assessment of these ideas. We analyze whether and to what degree the prescriptions have been implemented and whether or not certain fundamental changes seen in German flood management can be traced back to the application of the prescriptions. Our study demonstrates a transition from the traditional engineering and "flood control" approach to a more holistic management concept based on a risk perspective. In this process, the four ACM prescriptions have made an important contribution in preparing or facilitating policy changes. The findings suggest that the application of the prescriptions requires the right supporting context before they can be applied to the fullest extent possible, such as a high problem pressure, new discourses, or leading actors. A major constraint arises in the misalignment of political power and of the different interests of the actors, which contribute to reactive management and inadequate interplay. To address this, we recommend

  8. Genetics, genomics and fertility

    Science.gov (United States)

    In order to enhance the sustainability of dairy businesses, new management tools are needed to increase the fertility of dairy cattle. Genomic selection has been successfully used by AI studs to screen potential sires and significantly decrease the generation interval of bulls. Buoyed by the success...

  9. Fertility and Infertility.

    Science.gov (United States)

    Orgebin-Crist, Marie-Claire; And Others

    In this report, emphasis is placed on major research developments in the reproductive sciences, their impact on the health of individuals as well as on that of society, and on current trends that may provide new opportunities for future research in fertility and infertility. In the first section, major developments in the reproductive sciences are…

  10. Fertility and Infertility.

    Science.gov (United States)

    Orgebin-Crist, Marie-Claire; And Others

    In this report, emphasis is placed on major research developments in the reproductive sciences, their impact on the health of individuals as well as on that of society, and on current trends that may provide new opportunities for future research in fertility and infertility. In the first section, major developments in the reproductive sciences are…

  11. Mobility, Fertility, and Residential Crowding

    Science.gov (United States)

    Morris, Earl W.

    1977-01-01

    Regression analyses predicting fertility and mobility in a sample of a metropolitan county in New York State indicate that residential mobility serves to release the negative pressure that residential crowding might exert on fertility behavior. (Author)

  12. Agriculture: Nutrient Management and Fertilizer

    Science.gov (United States)

    Fertilizers and soil amendments can be derived from raw materials, composts and other organic matter, and wastes, such as sewage sludge and certain industrial wastes. Overuse of fertilizers can result in contamination of surface water and groundwater.

  13. Sex and Fertility After SCI

    Science.gov (United States)

    ... About Blog Facing Disability Jeff Shannon Donate Experts \\ Sex and Fertility After Spinal Cord Injury Topics Adult ... Spasticity, Physical Therapy-Lokomat Spasticity, Physical Therapy-Lokomat Sex and Fertility After Spinal Cord Injury Sex and ...

  14. A European community pharmacy-based survey to investigate patterns of prescription fraud through identification of falsified prescriptions

    NARCIS (Netherlands)

    Lapeyre-Mestre, Maryse; Gony, Mireille; Carvajal, Alfonso; Macias, Diego; Conforti, Anita; D'incau, Paola; Heerdink, Rob; Van Der Stichele, Robert; Bergman, Ulf

    2014-01-01

    Aim: To identify prescription drugs involved in falsified prescriptions in community pharmacies in 6 European countries. Methods: A cross-sectional survey among 2,105 community pharmacies in Belgium, France, Italy, the Netherlands, Spain and Sweden was carried out to collect all suspect prescription

  15. A European community pharmacy-based survey to investigate patterns of prescription fraud through identification of falsified prescriptions

    NARCIS (Netherlands)

    Lapeyre-Mestre, Maryse; Gony, Mireille; Carvajal, Alfonso; Macias, Diego; Conforti, Anita; D'incau, Paola; Heerdink, Rob; Van Der Stichele, Robert; Bergman, Ulf

    2014-01-01

    Aim: To identify prescription drugs involved in falsified prescriptions in community pharmacies in 6 European countries. Methods: A cross-sectional survey among 2,105 community pharmacies in Belgium, France, Italy, the Netherlands, Spain and Sweden was carried out to collect all suspect prescription

  16. [Drug design ideas and methods of Chinese herb prescriptions].

    Science.gov (United States)

    Ren, Jun-guo; Liu, Jian-xun

    2015-09-01

    The new drug of Chinese herbal prescription, which is the best carrier for the syndrome differentiation and treatment of Chinese medicine and is the main form of the new drug research and development, plays a very important role in the new drug research and development. Although there are many sources of the prescriptions, whether it can become a new drug, the necessity, rationality and science of the prescriptions are the key to develop the new drug. In this article, aiming at the key issues in prescriptions design, the source, classification, composition design of new drug of Chinese herbal prescriptions are discussed, and provide a useful reference for research and development of new drugs.

  17. A polycarbonate ophthalmic-prescription lens series.

    Science.gov (United States)

    Davis, J K

    1978-08-01

    Improvements in polycarbonate material, production techniques, and scratch-resistant coatings, combined with a process-oriented design, have resulted in a precision lens series. Surface quality is comparable to that of untreated glass ophthalmic lenses. The repeatability of the process results in closely controlled axial power and off-axis performance. For most lens prescriptions, the ANSI Z80.1 optical-center specifications for prescription accuracy are maintained through a total field of view of 40 deg for an 8-mm range of center-of-rotation distances. Off-axis astigmatism is controlled for near-point seeing. The lenses are both lighter and thinner than those of crown glass. A scratch-resistant coating reduces the reflections normally associated with high-index (1.586) materials. Impact resistance exceeds that required by ANSI Z80.7 and is many times that required by ANSI Z80.1.

  18. Women who doctor shop for prescription drugs.

    Science.gov (United States)

    Worley, Julie; Thomas, Sandra P

    2014-04-01

    Doctor shopping is a term used to describe a form of diversion of prescription drugs when patients visit numerous prescribers to obtain controlled drugs for illicit use. Gender differences exist in regard to prescription drug abuse and methods of diversion. The purpose of this phenomenological study guided by the existential philosophy of Merleau-Ponty was to understand the lived experience of female doctor shoppers. Interviews were conducted with 14 women, which were recorded, transcribed, and analyzed. Included in the findings are figural aspects of the participants' experience of doctor shopping related to the existential grounds of world, time, body, and others. Four themes emerged from the data: (a) feeding the addiction, (b) networking with addicts, (c) playing the system, and (d) baiting the doctors. The findings suggest several measures that nurses can take to reduce the incidence of doctor shopping and to provide better care for female doctor shoppers.

  19. Information prescriptions: A tool for veterinary practices

    Directory of Open Access Journals (Sweden)

    L.R. Kogan

    2014-09-01

    Full Text Available The Internet has become a major source of health information and has the potential to offer many benefits for both human and animal health. In order for impact to be positive, however, it is critical that users be able to access reliable, trustworthy information. Although more pet owners are using the Internet to research animal health information than ever before, there remains limited research surrounding their online activities or the ability to influence owners’ online search behaviors. The current study was designed to assess the online behaviors and perceptions of pet owners after receiving either general or topic-specific information prescriptions as part of their veterinary appointment. Results indicate that nearly 60% of clients accessed the suggested websites and nearly all of these clients reported positive feelings about this addition to their veterinary services. These results suggest that offering information prescriptions to clients can facilitate better online searches by clients and positively impact both animal health and client satisfaction.

  20. Price Sensitivity of Demand for Prescription Drugs

    DEFF Research Database (Denmark)

    Simonsen, Marianne; Skipper, Lars; Skipper, Niels

    2016-01-01

    We investigate price sensitivity of demand for prescription drugs, using drug purchase records for the entire Danish population. We identify price responsiveness by exploiting variation in prices caused by kinked reimbursement schemes and implement a regression kink design. The results suggest so...... price responsiveness with corresponding price elasticities ranging from −0.2 to −0.7. Individuals with chronic disease and especially individuals above the age of 65 respond less to the price of drugs.......We investigate price sensitivity of demand for prescription drugs, using drug purchase records for the entire Danish population. We identify price responsiveness by exploiting variation in prices caused by kinked reimbursement schemes and implement a regression kink design. The results suggest some...

  1. Vital Signs-Preventing Prescription Drug Overdose

    Centers for Disease Control (CDC) Podcasts

    2014-07-01

    This podcast is based on the July 2014 CDC Vital Signs report. Every day, 46 people in the U.S. die from an overdose of prescription opioid painkillers. Learn what can be done to make painkiller prescribing safer and help prevent overdoses.  Created: 7/1/2014 by National Center for Immunization and Respiratory Diseases (NCIRD).   Date Released: 7/1/2014.

  2. Preventing Prescription Drug Overdose PSA (:60)

    Centers for Disease Control (CDC) Podcasts

    2014-07-01

    This 60 second public service announcement is based on the July 2014 CDC Vital Signs report. Every day, 46 people in the U.S. die from an overdose of prescription opioid painkillers. Learn what can be done to make painkiller prescribing safer and help prevent overdoses.  Created: 7/1/2014 by National Center for Immunization and Respiratory Diseases (NCIRD).   Date Released: 7/1/2014.

  3. Arts on prescription: a qualitative outcomes study.

    Science.gov (United States)

    Stickley, T; Eades, M

    2013-08-01

    In recent years, participatory community-based arts activities have become a recognized and regarded method for promoting mental health. In the UK, Arts on Prescription services have emerged as a prominent form of such social prescribing. This follow-up study reports on the findings from interviews conducted with participants in an Arts on Prescription programme two years after previous interviews to assess levels of 'distance travelled'. This follow-up study used a qualitative interview method amongst participants of an Arts on Prescription programme of work. Ten qualitative one-to-one interviews were conducted in community-based arts venues. Each participant was currently using or had used mental health services, and had been interviewed two years earlier. Interviews were digitally recorded, transcribed and analysed. For each of the 10 participants, a lengthy attendance of Arts on Prescription had acted as a catalyst for positive change. Participants reported increased self-confidence, improved social and communication skills, and increased motivation and aspiration. An analysis of each of the claims made by participants enabled them to be grouped according to emerging themes: education: practical and aspirational achievements; broadened horizons: accessing new worlds; assuming and sustaining new identities; and social and relational perceptions. Both hard and soft outcomes were identifiable, but most were soft outcomes. Follow-up data indicating progress varied between respondents. Whilst hard outcomes could be identified in individual cases, the unifying factors across the sample were found predominately in the realm of soft outcomes. These soft outcomes, such as raised confidence and self-esteem, facilitated the hard outcomes such as educational achievement and voluntary work. Copyright © 2013 The Royal Society for Public Health. Published by Elsevier Ltd. All rights reserved.

  4. Price Sensitivity of Demand for Prescription Drugs

    DEFF Research Database (Denmark)

    Skipper, Lars; Simonsen, Marianne; Skipper, Niels

    This paper investigates price sensitivity of demand for prescription drugs using drug purchase records for at 20% random sample of the Danish population. We identify price responsiveness by exploiting exogenous variation in prices caused by kinked reimbursement schemes and implement a regression ...... education and income are, however, more responsive to the price. Also, essential drugs that prevent deterioration in health and prolong life have lower associated average price sensitivity....

  5. [Evaluation of quality medication prescription of a teaching hospital].

    Science.gov (United States)

    Araújo, Patrícia Taveira de Brito; Uchôa, Severina Alice Costa

    2011-01-01

    The errors from doctor prescriptions can cause damage to the patient's health, consequently it is necessary to identify and to prevent them. This work aimed to evaluate if the legal and institutional aspects that are present in doctor prescription at the public and university pediatric hospital to make a diagnosis from the situation, and then to correct the problems. A survey was made was made using a cross-sectional method, where copies of 1,590 prescriptions were studied after the University Committee of Research approved the survey. The average was 4.47 drugs per prescription and following data were detectable: readable--32.39% of the prescriptions were unreadable, 49.81% presented only the commercial name, 5.25% of the drugs were not standardized. Quality of prescription in the chosen hospital needs to be better to avoid medication errors and the health care process gets safer. When prescription is unreadable, they can confuse health professionals and damage patients.

  6. Increasing access to emergency contraception through online prescription requests.

    Science.gov (United States)

    Averbach, Sarah; Wendt, Jacqueline Moro; Levine, Deborah K; Philip, Susan S; Klausner, Jeffrey D

    2010-01-01

    To describe a pilot program, Plan B Online Prescription Access, to provide easy access to prescriptions for emergency contraception via the Internet. We measured electronic prescriptions for Plan B (Duramed Pharmaceuticals, Cincinnati, Ohio) by month over time. Pharmacists faxed patient-generated prescriptions back to the Department of Public Health for confirmation. Despite no marketing, within the first 18 months of the program, 152 electronic prescriptions for Plan B were requested by 128 female San Francisco residents. Seventy-eight prescriptions were filled (51%) by pharmacists. If correctly marketed, online prescriptions for Plan B have the potential to be an effective means of increasing emergency contraception access in both urban and rural settings across the United States. Further user-acceptability studies are warranted.

  7. Reviewing prescription spending and accessory usage.

    Science.gov (United States)

    Oxenham, Julie

    This article aims to explore the role of the stoma nurse specialist in the community and how recent initiatives within the NHS have impacted on the roles in stoma care to react to the rising prescription costs in the specialty. The article will explore how the stoma care nurse conducted her prescription reviews within her own clinical commissioning group (CCG). The findings of the reviews will be highlighted by a small case history and a mini audit that reveals that some stoma patients may be using their stoma care accessories inappropriately, which may contribute to the rise in stoma prescription spending. To prevent the incorrect use of stoma appliances it may necessitate an annual review of ostomates (individuals who have a stoma), as the author's reviews revealed that inappropriate usage was particularly commonplace when a patient may have not been reviewed by a stoma care specialist for some considerable amount of time. Initial education of the ostomate and ongoing education of how stoma products work is essential to prevent the misuse of stoma appliances, particularly accessories, as the reviews revealed that often patients were not always aware of how their products worked in practice.

  8. Natural fertility in the Philippines.

    Science.gov (United States)

    Aquino, E G

    1982-01-01

    The hypothesis that modernization trends in the Philippines led to an increase in fecundity and natural fertility between 1953-1972 was tested, using data from the 1973 National Demographic Survey. More specifically, it was hypothesized that increases in education, income levels, urbanization, female labor force participation, and other factors exerted a positive influence on the population's health and nutritional status and increased the risk of pregnancy by diminishing the strength of sexual taboos and by decreasing the incidence of breastfeeding. These changes, in turn, had a positive impact on natural fertility. Natural fertility was defined as marital fertility in the absence of specific efforts to control fertility. The use of natural fertility instead of fecundity allowed for the influence of behavioral patterns, such as breastfeeding and sexual taboos, on fertility. Period analysis of age specific marital fertility rates for each 5 year period between 1953-72 and cohort analysis of age specific marital fertility rates for the birth cohorts, aged 55-59, 50-54, 45-49, 40-44, and 35-39 in 1973 were undertaken. The effect of fertility control was determined by using an index derived from an equation provided by Coale and Trussell. Findings of both the period and cohort analysis supported the hypothesis. Period analysis revealed that natural fertility increased between 1953-57 and 1969-72 by 10% and that the greatest increase occurred during the 1950s when Philippine society experienced major modernization changes. The increases in natural fertility were accompanied by corresponding increases in fertility regulation in each time period. These trends tended to cancel each other out and resulted in a relatively stable total marital fertility rate throughout the time period. Cohort analysis revealed that only the total marital fertility rate of the youngest cohort was influenced by fertility regulation. The level of natural fertility for all cohorts as a group

  9. [Risks of non-prescription medication. Clobutinol cough syrup as a recent example].

    Science.gov (United States)

    Rottlaender, D; Hoppe, U C

    2008-01-01

    The arbitrary use of additional drugs other than prescribed medication is known to be a huge part of drug sales. However, the interactions of such non-prescription medication with any daily medication or concomitant diseases remain often unclear. Recently, in accordance with the decision of the competent authority in Germany, clobutinol (e.g. Silomat), a drug against non-productive cough was withdrawn in all countries worldwide in which this medication had been available. The drug had first been approved in 1961 and estimated to have had 200 million patient exposures. A recent clinical study revealed that clobutinol can prolong the QT interval compared to placebo and may thus cause cardiac tachyarrhythmias. Even in therapeutic doses (240 mg daily) this effect was seen in healthy volunteers. Furthermore, this study was prematurely discontinued because of an epileptic grand mal seizure in one volunteer, suggesting neurological side effects of clobutinol. Clobutinol prolongs the QT interval and may cause life-threatening arrhythmias. This should serve as a warning to doctors to be careful when prescribing non-prescription medication. Non-prescription drugs can be a potential risk for patients who are also taking other pharmaceutical preparations or having concomitant disease. This is because such drugs may cause harmful interactions, most of them previously unknown. All doctors should avoid unsupervised use of non-prescription medication.

  10. Social mobility and fertility

    Directory of Open Access Journals (Sweden)

    Gianpiero Dalla Zuanna

    2007-12-01

    Full Text Available Intra- and inter-generational social mobility have in the past played an important role in attempts to explain fertility behaviour, and continue to do so today. The opinions expressed by social scientists in the first part of the 20th century are renewed and confirmed. More specifically: (1 intra-generational social mobility has been reinforced by the personal well-being aspirations and job careers of women; (2 status anxiety parents feel for their children pushes fertility down in large areas of the developed world (mainly in southern European and eastern Asian countries. Therefore, the provocative idea of Ariès that in the rich world, the child-king has now been replaced by the couple-queen does not perfectly hold.

  11. Diversity in the fertilization envelopes of echinoderms.

    Science.gov (United States)

    Oulhen, Nathalie; Reich, Adrian; Wong, Julian L; Ramos, Isabela; Wessel, Gary M

    2013-01-01

    Cell surface changes in an egg at fertilization are essential to begin development and for protecting the zygote. Most fertilized eggs construct a barrier around themselves by modifying their original extracellular matrix. This construction usually results from calcium-induced exocytosis of cortical granules, the contents of which in sea urchins function to form the fertilization envelope (FE), an extracellular matrix of cortical granule contents built upon a vitelline layer scaffold. Here, we examined the molecular mechanism of this process in sea stars, a close relative of the sea urchins, and analyze the evolutionary changes that likely occurred in the functionality of this structure between these two organisms. We find that the FE of sea stars is more permeable than in sea urchins, allowing diffusion of molecules in excess of 2 megadaltons. Through a proteomic and transcriptomic approach, we find that most, but not all, of the proteins present in the sea urchin envelope are present in sea stars, including SFE9, proteoliaisin, and rendezvin. The mRNAs encoding these FE proteins accumulated most densely in early oocytes, and then beginning with vitellogenesis, these mRNAs decreased in abundance to levels nearly undetectable in eggs. Antibodies to the SFE9 protein of sea stars showed that the cortical granules in sea star also accumulated most significantly in early oocytes, but different from sea urchins, they translocated to the cortex of the oocytes well before meiotic initiation. These results suggest that the preparation for cell surface changes in sea urchins has been shifted to later in oogenesis, and perhaps reflects the meiotic differences among the species-sea star oocytes are stored in prophase of meiosis and fertilized during the meiotic divisions, as in most animals, whereas sea urchins are one of the few taxons in which eggs have completed meiosis prior to fertilization.

  12. Diversity in the fertilization envelopes of echinoderms

    Science.gov (United States)

    Oulhen, Nathalie; Reich, Adrian; Wong, Julian L.; Wessel, Gary M.

    2013-01-01

    Cell surface changes in an egg at fertilization are essential to begin development and for protecting the zygote. Most fertilized eggs construct a barrier around themselves by modifying their original extracellular matrix. This construction usually results from calcium induced exocytosis of cortical granules, the contents of which in sea urchins function to form the fertilization envelope (FE), an extracellular matrix of cortical granule contents built upon a vitelline layer scaffold. Here we examined the molecular mechanism of this process in sea stars, a close relative of the sea urchins, and analyze the evolutionary changes that likely occurred in the functionality of this structure between these two organisms. We find that the FE of sea stars is more permeable than in sea urchins, allowing diffusion of molecules in excess of 2 megadaltons. Through a proteomic and transcriptomic approach, we find that most, but not all of the proteins present in the sea urchin envelope are present in sea stars, including SFE9, proteoliaisin, rendezvin, and ovoperoxidase. The mRNAs encoding these FE proteins accumulated most densely in early oocytes, and then beginning with vitellogenesis, these mRNAs deceased in abundance to levels nearly undetectable in eggs. Antibodies to the SFE9 protein of sea stars showed that the cortical granules in sea star also accumulated most significantly in early oocytes, and different from sea urchins, they translocated to the cortex of the oocytes well before meiotic initiation. These results suggest that the preparation of the cell surface changes in sea urchins has been shifted to later in oogenesis and perhaps reflects the meiotic differences among the species–sea star oocytes are stored in prophase of meiosis and fertilized during the meiotic divisions, as in most animals, whereas sea urchins are one of the few taxa in which eggs have completed meiosis prior to fertilization. PMID:23331915

  13. Fertility, Migration, and Altruism

    OpenAIRE

    2000-01-01

    Consider migration to a higher income region as a human capital investment in which parents bear migration costs and children share returns. Migrants from a population with heterogeneous intergenerational discount rates will be self-selected on intergenerational altruism. Thus, immigrants may be self-selected on fertility. Soviet Jews who migrate to Israel despite high migration costs have significantly more children than members of the same birth cohort who migrate later when costs are low. ...

  14. Slow-Release Fertilizer

    Science.gov (United States)

    1998-01-01

    Under an SBIR (Small Business Innovative Research), ZeoponiX, Inc., introduced ZeoPro. This product is used as a fertilizer/soil amendment for golf courses, ball fields, greenhouse and horticultural uses. A combination of superior growth medium and soil conditioner allow for nutrient supplementation and high efficiency delivery of nutrients throughout the plant. ZeoPro provides a balanced nutrient system for major, minor, and trace nutrients.

  15. The fertility decline in Kenya.

    Science.gov (United States)

    Robinson, W C; Harbison, S F

    1995-01-01

    In Sub-Saharan Africa Kenya is a prime example of a country experiencing a rapid decline in fertility and greater contraceptive prevalence. These changes have occurred since 1980 when fertility was high at 8.0 children per woman. In 1993 the total fertility rate (TFR) was 5.4, and the growth rate declined to about 2.0%. This transition is swifter than any country in contemporary Asia or historical Europe. The likely projection for Kenya is attainment of replacement level fertility during the 2020s and a leveling of population at about 100 million persons. Fertility has declined the most in urban areas and central and eastern regions. Bongaarts' proximate determinants (TFR, total marital fertility rate, total natural marital fertility rate, and total fecundity) are reduced to the proportion of currently married women using contraception, the proportion in lactational nonfecund status, and the proportion currently married. Actual fertility change is accounted for by total fertility change of 3.0 children. Lactational infecundability accounts for 0.5 potential births, and changes in marital fertility account for 1.0 reduced births per woman. About 70% of fertility reduction is accounted for by contraception and abortion. During 1977-78 80% of fertility control was due to lactational nonfecundity, 10% to nonmarriage, and 10% to contraception. In 1993 lactational nonfecundity accounted for 50% of the reduction, nonmarriage for 20%, and abortion about 30%. Future fertility is expected to be dependent on contraceptive prevalence. Kenya has experienced the Coale paradigm of preconditions necessary for demographic transition (willing, ready, and able). High fertility in Africa is not intractable. Creating the change in attitudes that leads to readiness is linked to education, health, and exposure to modernizing media and urban lifestyles. The public sector family planning program in Kenya has created the opportunity for access and availability of contraception. The key

  16. IN VITRO FERTILIZATION

    Directory of Open Access Journals (Sweden)

    Hadawale N. M

    2011-07-01

    Full Text Available First written document dealing with infertility may be found in the Kahoun papyrus (oldest Egyptian medical text, dated to 2200-1950 BC. The early attribution of infertility to women persisted for centuries and was often considered divine punishment.Infertility means 1 year of well-timed, unprotected intercourse without a pregnancy. The study shows about 10-15% of population is infertile. And 15-20% of couple have unexplained infertility (work-up is negative. Normally women are born with their lifetime egg supply, the Fertility initially declines at age 27.Significant decline at age 37-38. The chances of pregnancies are rare after age 44 besides this defect in female ovary, fallopian tube, uterus, and fibroid tumour causes infertility in female.Abnormality in sperm production and abnormality in sperm function causes infertility in male.To overcome the infertility egg are harvested from womens ovary and fertilized in laboratory with the sperm the embryos are then transfer into uterus known as In Vitro Fertilization.

  17. Environmental friendly nitrogen fertilization

    Institute of Scientific and Technical Information of China (English)

    Avi; Shaviv

    2005-01-01

    With the huge intensification of agriculture and the increasing awareness to human health and natural resources sustainability, there was a shift towards the development of environmental friendly N application approaches that support sustainable use of land and sustain food production.The effectiveness of such approaches depends on their ability to synchronize plant nitrogen demand with its supply and the ability to apply favored compositions and dosages of N-species.They are also influenced by farming scale and its sophistication, and include the following key concepts: (i) Improved application modes such as split or localized ("depot") application; (ii) use of bio-amendments like nitrification and urease inhibitors and combinations of (i) and (ii); (iii) use of controlled and slow release fertilizers; (iv) Fertigation-fertilization via irrigation systems including fully automated and controlled systems; and (v) precision fertilization in large scale farming systems. The paper describes the approaches and their action mechanisms and examines their agronomic and environmental significance. The relevance of the approaches for different farming scales, levels of agronomic intensification and agro-technical sophistication is examined as well.

  18. Chinese culture and fertility decline.

    Science.gov (United States)

    Wu, C; Jia, S

    1992-01-01

    Coale has suggested that cultural factors exert a significant influence on fertility reduction; countries in the "Chinese cultural circle" would be the first to show fertility decline. In China, the view was that traditional Chinese culture contributed to increased population. This paper examines the nature of the relationship between Chinese culture and fertility. Attention was directed to a comparison of fertility rates of developing countries with strong Chinese cultural influence and of fertility within different regions of China. Discussion was followed by an explanation of the theoretical impact of Chinese culture on fertility and direct and indirect beliefs and practices that might either enhance or hinder fertility decline. Emigration to neighboring countries occurred after the Qing dynasty. Fertility after the 1950s declined markedly in Japan, Singapore, Hong Kong, South Korea, Taiwan, and mainland China: all countries within the Chinese cultural circle. Other countries within the Chinese circle which have higher fertility, yet lower fertility than other non-Chinese cultural countries, are Malaysia, Thailand, and Indonesia. Within China, regions with similar fertility patterns are identified as coastal regions, central plains, and mountainous and plateau regions. The Han ethnic group has lower fertility than that of ethnic minorities; regions with large Han populations have lower fertility. Overseas Chinese in East Asian countries also tend to have lower fertility than their host populations. Chinese culture consisted of the assimilation of other cultures over 5000 years. Fertility decline was dependent on the population's desire to limit reproduction, favorable social mechanisms, and availability of contraception: all factors related to economic development. Chinese culture affects fertility reduction by affecting reproductive views and social mechanisms directly, and indirectly through economics. Confucianism emphasizes collectivism, self

  19. DEVELOPMENT OF MICROFLORA IN APPLE ROOT RHIZOSPERE WHEN FERTILIZING

    Directory of Open Access Journals (Sweden)

    Kuzin A. I.

    2015-09-01

    Full Text Available The problem of environmental safety of agricultural products and agro-technical measures is very urgent now. Various agrochemicals are widely used in agricultural production: plant protection preparations, fertilizers, stimulants and plant growth regulators, etc. One possible solution of this problem may be a partial replacement of mineral fertilizers by bacterial ones. The aim of our research was to determine the effect of different fertilizers and methods of their application on the quantity of microorganisms in the apple root rhizosphere soil. The research was carried out according to conventional methods. In our experiment, we determined the number of microorganisms in the rhizosphere of the roots of apple trees, nitrogen, phosphorus and potassium in the leaves; hydrolysable nitrogen, available phosphorus and exchangeable potassium in soil and crop yield. The highest yield was obtained by fertigation in our research. Application bacterial fertilizer to the soil ensured yield increase at the level of mineral fertilizer application. Application of fertilizers in general, in the studied application rates provided optimum level of nitrogen, phosphorus and potassium content in the leaves and soil. By use of fertigation and bacterial fertilizers were high and relatively stable numbers of microorganisms in the rhizosphere of the apple trees. The number of microorganisms in the rhizosphere had a positive correlation with yield and the content of nutrients in soil and in leaves

  20. Prescription Drug Misuse and Sexual Behavior Among Young Adults.

    Science.gov (United States)

    Wells, Brooke E; Kelly, Brian C; Rendina, H Jonathon; Parsons, Jeffrey T

    2015-01-01

    Though research indicates a complex link between substance use and sexual risk behavior, there is limited research on the association between sexual risk behavior and prescription drug misuse. In light of alarming increases in prescription drug misuse and the role of demographic characteristics in sexual risk behavior and outcomes, the current study examined demographic differences (gender, sexual identity, age, relationship status, parental class background, and race/ethnicity) in sexual risk behavior, sexual behavior under the influence of prescription drugs, and sexual risk behavior under the influence of prescription drugs in a sample of 402 young adults (ages 18 to 29) who misused prescription drugs. Nearly half of the sexually active young adult prescription drug misusers in this sample reported recent sex under the influence of prescription drugs; more than three-quarters reported recent sex without a condom; and more than one-third reported recent sex without a condom after using prescription drugs. Zero-inflated Poisson regression models indicated that White race, younger age, higher parental class, and being a heterosexual man were all associated with sexual risk behavior, sex under the influence of prescription drugs, and sexual risk under the influence of prescription drugs. Findings have implications for the targeting of prevention and intervention efforts.

  1. Development of the knowledge of fertility and fertility preservation scale

    Directory of Open Access Journals (Sweden)

    McNees P

    2012-04-01

    Full Text Available Angela Jukkala1, Karen Meneses1, Andres Azuero1, June Cho1, Patrick McNees1,21School of Nursing, 2School of Health Professions, University of Alabama at Birmingham, Birmingham, AL, USAObjective: Infertility is a severe and often underestimated consequence of successful treatment for breast cancer. Ensuring young breast cancer survivors receive patient-centered health information on the impact of treatment on fertility and fertility preservation options in a timely manner is a critical component of high quality nursing care. The objective of this manuscript is to report the process used to develop and examine the reliability and validity of an instrument to measure a breast cancer survivor’s self-assessed knowledge of fertility and fertility preservation.Design: A scale development and descriptive study.Setting: Online and global.Participants: Ninety-two young breast cancer survivors (ages 25–45 years.Methods: Participants completed the Knowledge of Fertility and Fertility Preservation (KF Scale as part of their participation in a larger study, the Fertility Cancer Project (FCP.Results: An exploratory factor analysis revealed five domains: normal reproductive function; general information about fertility; cancer treatment factors affecting fertility; infertility information; and alternative parenting options. A confirmatory factor analysis confirmed the validity of the construct with a demonstrated good fit between the factor structure of the new scale and the observed data. Many participants self-assessed their overall knowledge of fertility and fertility preservation as “a little” and the majority rated their knowledge of infertility information as “a little”.Conclusion: The KF Scale can be used to provide useful information to support health care professionals in the development of patient-centered education that is responsive to the unique needs of each young breast cancer survivor. The initial testing of the KF Scale indicates

  2. Semen preparation techniques for intrauterine insemination

    NARCIS (Netherlands)

    Boomsma, Carolien M.; Heineman, M. J.; Cohlen, B. J.; Farquhar, C.

    2007-01-01

    Background Semen preparation techniques for assisted reproduction, including intrauterine insemination (IUI), were developed to separate the motile morphological normal spermatozoa. Leucocytes, bacteria and dead spermatozoa produce oxygen radicals that negatively influence the ability to fertilize

  3. Semen preparation techniques for intrauterine insemination

    NARCIS (Netherlands)

    Boomsma, C. M.; Heineman, M. J.; Cohlen, B. J.; Farquhar, C.

    2007-01-01

    Background Semen preparation techniques for assisted reproduction, including intrauterine insemination (IUI), were developed to separate the motile morphological normal spermatozoa. Leucocytes, bacteria and dead spermatozoa produce oxygen radicals that negatively influence the ability to fertilize t

  4. Knowledge of drug prescription in dentistry students

    Directory of Open Access Journals (Sweden)

    Guzmán-Álvarez R

    2012-06-01

    Full Text Available R Guzmán-Álvarezv,1 M Medeiros,2,3 LI Reyes Lagunes,4 AE Campos-Sepúlveda11Pharmacology Department, UNAM School of Medicine and Dentistry, Mexico City, 2Pharmacology Clinical Seminar, UNAM School of Medicine, Mexico City, 3Medical Sciences Department, Mexico Federico Gómez Children's Hospital, Mexico City, 4Measuring and Evaluation Unit, UNAM School of Psychology, Mexico City, MexicoBackground: Students in schools of dentistry attend to patients with illnesses, and often prescribe medication. Because students are still learning, they are influenced by a variety of factors: the different teaching approaches of the professors at the clinics and in the pharmacology course, fellow students, and even the information provided by the pharmaceutical industry.Objectives: The aim of this pilot study was to assess the prescription knowledge and common mistakes in fourth-year students at the School of Dentistry at the Universidad Nacional Autónoma de México.Methods: In March 2010, a survey was conducted among 66 fourth-year students at the School of Dentistry, applying a previously validated questionnaire consisting of six open-ended questions The following factors were assessed: the most frequent illness requiring dental prescription; the most prescribed nonsteroidal anti-inflammatory drugs and antibiotics; the most frequent errors; sources of information used for prescribing drugs; and whether the students knew and followed the World Health Organization Guide to Good Prescribing.Results: The most frequent response for each question was considered the most significant. The most common reason for prescribing medication was infection (n = 37, 56%, followed by pain (n = 24, 38%; the most used painkillers were ibuprofen and acetaminophen at equal levels (n = 25, 37.8%, followed by ketorolac (n = 7, 10.6%, naproxen (n = 6, 9.1%, diclofenac (n = 2, 3%, and aspirin (n = 1, 1.5%; the most widely prescribed antibiotics were amoxicillin (n = 52, 78

  5. Fabrication and evaluation of variable rate fertilizer system

    Directory of Open Access Journals (Sweden)

    A Damirchi

    2015-09-01

    Full Text Available Introduction: In conventional farming, the soil and crop are considered uniform in different locations of the farm and the fertilizers are applied according to the average of soil needs with an additional percentage for safety (Loghavi, 2003. Non-essential chemical fertilizers in the field have harmful effects and social, economic and environmental concerns will increase. Many fertilizers go into the surface waters and ground waters and cause poisoning and environmental pollution without being absorbed by the plants. In variable rate technology, the soil fertilizer needs a map of all parts of the farm which is prepared with the GIS system. This map is uploaded on the computer before variable rate fertilizer machine starts. The computer continually controls the fertilizing rate for each part of the farm using a fertilizing map and global positioning system. The purpose of this study is to construct and evaluate a map-based variable rate fertilizer system that can be installed on a common fertilizer in Iran to be used as a variable rate system. Materials and methods: In common variable rate fertilizers, the rotational speed change of the distributor shaft is used to apply fertilizers. In this way, a DC motor is assembled on the main shaft of all distributors, which reduces the fertilizing accuracy. The reason for this is that there is no separation for units along the width of the fertilizer. Therefore, we used one DC motor for each distributor and another motor to rotate the agitator in the tank. System Set up: To design and select a suitable engine, the required torque for the rotation distributor shaft was measured by a torque meter and the amount of 2.1 Nm was acquired for that. With regard to the maximum rate of nitrogen fertilizer for land and tractor speed at the time of fertilizing, the order of 350 kg per hectare and 8 km per hour, the maximum distributor shaft speed and power required to rotate distributor shaft were calculated to be 55

  6. Temporal Trends in Fertility Rates

    DEFF Research Database (Denmark)

    Jensen, Martin Blomberg; Priskorn, Lærke; Jensen, Tina Kold

    2015-01-01

    to determine total and age specific fertility rates. RESULTS: Total fertility rate (TFR) decreased from 4.1 to 1.8 children per woman and age specific fertility also decreased from 1901 to 2014. Women aged 30-34, 35-39 or 40-44 years in the first decade of the 20th century had higher fertility rates than......OBJECTIVE: Increasing age at first childbirth has been suggested to increase the risk for infertility. Our objective is to determine whether women above thirty years of age historically have been able to sustain fertility rates above replacement level. DESIGN: A descriptive nationwide Danish study...... for 10% of TFR in 1901 compared with 4% in 2014 despite usage of assisted reproduction. CONCLUSION: This nationwide study shows that women above 30 years of age historically have been able to sustain fertility rates above replacement level. This implies that other factors besides age are strong...

  7. Hydrolytic Amino Acids Employed as a Novel Organic Nitrogen Source for the Preparation of PGPF-Containing Bio-Organic Fertilizer for Plant Growth Promotion and Characterization of Substance Transformation during BOF Production.

    Science.gov (United States)

    Zhang, Fengge; Meng, Xiaohui; Feng, Chenglong; Ran, Wei; Yu, Guanghui; Zhang, Yingjun; Shen, Qirong

    2016-01-01

    Opportunity costs seriously limit the large-scale production of bio-organic fertilizers (BOFs) both in China and internationally. This study addresses the utilization of amino acids resulting from the acidic hydrolysis of pig corpses as organic nitrogen sources to increase the density of TrichodermaharzianumT-E5 (a typical plant growth-promoting fungi, PGPF). This results in a novel, economical, highly efficient and environmentally friendly BOF product. Fluorescence excitation-emission matrix (EEM) spectroscopy combined with fluorescence regional integration (FRI) was employed to monitor compost maturity levels, while pot experiments were utilized to test the effects of this novel BOF on plant growth. An optimization experiment, based on response surface methodologies (RSMs), showed that a maximum T-E5 population (3.72 × 108 ITS copies g-1) was obtained from a mixture of 65.17% cattle manure compost (W/W), 19.33% maggot manure (W/W), 15.50% (V/W)hydrolytic amino acid solution and 4.69% (V/W) inoculum at 28.7°C after a 14 day secondary solid fermentation. Spectroscopy analysis revealed that the compost transformation process involved the degradation of protein-like substances and the formation of fulvic-like and humic-like substances. FRI parameters (PI, n, PII, n, PIII, n and PV, n) were used to characterize the degree of compost maturity. The BOF resulted in significantly higher increased chlorophyll content, shoot length, and shoot and root dry weights of three vegetables (cucumber, tomato and pepper) by 9.9%~22.4%, 22.9%~58.5%, 31.0%~84.9%, and 24.2%~34.1%, respectively. In summary, this study presents an operational means of increasing PGPF T-E5 populations in BOF to promote plant growth with a concomitant reduction in production cost. In addition, a BOF compost maturity assessment using fluorescence EEM spectroscopy and FRI ensured its safe field application.

  8. Hydrolytic Amino Acids Employed as a Novel Organic Nitrogen Source for the Preparation of PGPF-Containing Bio-Organic Fertilizer for Plant Growth Promotion and Characterization of Substance Transformation during BOF Production.

    Directory of Open Access Journals (Sweden)

    Fengge Zhang

    Full Text Available Opportunity costs seriously limit the large-scale production of bio-organic fertilizers (BOFs both in China and internationally. This study addresses the utilization of amino acids resulting from the acidic hydrolysis of pig corpses as organic nitrogen sources to increase the density of TrichodermaharzianumT-E5 (a typical plant growth-promoting fungi, PGPF. This results in a novel, economical, highly efficient and environmentally friendly BOF product. Fluorescence excitation-emission matrix (EEM spectroscopy combined with fluorescence regional integration (FRI was employed to monitor compost maturity levels, while pot experiments were utilized to test the effects of this novel BOF on plant growth. An optimization experiment, based on response surface methodologies (RSMs, showed that a maximum T-E5 population (3.72 × 108 ITS copies g-1 was obtained from a mixture of 65.17% cattle manure compost (W/W, 19.33% maggot manure (W/W, 15.50% (V/Whydrolytic amino acid solution and 4.69% (V/W inoculum at 28.7°C after a 14 day secondary solid fermentation. Spectroscopy analysis revealed that the compost transformation process involved the degradation of protein-like substances and the formation of fulvic-like and humic-like substances. FRI parameters (PI, n, PII, n, PIII, n and PV, n were used to characterize the degree of compost maturity. The BOF resulted in significantly higher increased chlorophyll content, shoot length, and shoot and root dry weights of three vegetables (cucumber, tomato and pepper by 9.9%~22.4%, 22.9%~58.5%, 31.0%~84.9%, and 24.2%~34.1%, respectively. In summary, this study presents an operational means of increasing PGPF T-E5 populations in BOF to promote plant growth with a concomitant reduction in production cost. In addition, a BOF compost maturity assessment using fluorescence EEM spectroscopy and FRI ensured its safe field application.

  9. Diagnosis-prescription studies – important steps towards a national drug prescription statistics in Norway

    Directory of Open Access Journals (Sweden)

    Jørund Straand

    2009-11-01

    Full Text Available  ABSTRACTIn the first part of this article, drug utilization and prescribing practice is discussed as seen from aNorwegian general practice perspective. Which are the data sources available? What kind of studieshave been performed? Prescription-diagnosis studies are reviewed, in particular the Møre & RomsdalPrescription Study (MRPS. Because the wholesales drug statistics do not include information aboutneither patients, prescribers or diagnoses, there is a current need for establishing a more comprehensivestatistics giving wider and deeper insights into the prescribing and utilization of drugs in the Norwegiansociety. The proposed Norwegian prescription statistics is discussed in relation to previous experiencesfrom prescription-diagnosis studies and current needs for research and statistics in the field. Someexamples are given illustrating why the 11-digit person number probably should be included in thedatabase. Lack of diagnostic information may to some extent be compensated for by introducing a moredifferentiated list of diagnoses for the drugs reimbursed. The use of data from this statistics for qualityassurance in e.g. general practice is discussed. Finally, some suggestions are given for how the Norwegianprescription statistics may be organised.

  10. Fertility and age

    Directory of Open Access Journals (Sweden)

    Korula George

    2010-01-01

    Full Text Available The changing social scenario together with economic growth and an increase in job opportunities has to a great extent reduced gender inequality and has resulted in more and more older women seeking help from infertility clinics. Fertility and aging have always been closely linked and the age of the female partner remains the single most important factor in predicting success with treatment. Although tests for the ovarian reserve are an important informative tool and are helpful in selecting treatment options, they are poor predictors of the outcome.

  11. WILL FERTILITY REBOUND IN JAPAN

    OpenAIRE

    Creina Day

    2012-01-01

    Fertility and per capita income are now positively associated across most high income OECD countries. Low fertility and a gender wage gap persist in Japan. This paper presents an original model where endogenous increases in childcare prices and gender equity in capital allocation play important roles in the effect of per capita income growth and rising female relative wages on fertility. Results suggest Japan has cause for optimism. Economic growth will raise female relative wages where capit...

  12. Soils and Fertilizers. Competency Based Teaching Materials in Horticulture.

    Science.gov (United States)

    Legacy, Jim; And Others

    This competency-based curriculum unit on soils and fertilizers is one of four developed for classroom use in teaching the turf and lawn services area of horticulture. The four sections are each divided into teaching content (in a question-and-answer format) and student skills that outline taking soil samples, testing samples, preparing soil for…

  13. [Medicinal products for human use in veterinary prescription].

    Science.gov (United States)

    Kolář, Jozef; Vargová, Lucia; Ambrus, Tünde

    2015-09-01

    The paper deals with the problem of prescription and use of the medicinal products for human use in veterinary medicine. Using partial model analysis describes volume and structure of the prescription of medicinal products for human use in the veterinary practice in the years 2007-2011. Prescriptions included to the study were dispensed in a community pharmacy located in a county town in the Slovak Republic. Data were obtained from the basic collection of 845 veterinary prescriptions that included 1178 prescribed items in a total of 2954 packages.

  14. Prescription Writing Errors of Midwifery Students in Common Gynecological problems

    Directory of Open Access Journals (Sweden)

    Serveh Parang

    2014-04-01

    Full Text Available Background and aim: Giving improper prescriptions is common among medical practitioners, mostly graduates, in most communities even developed countries. So far, to our knowledge, no study has been conducted on prescription writing of graduate midwifery students. Therefore, this study aimed to detect prescription writing errors of midwifery students in common gynecological problems. Methods: In this descriptive cross-sectional study, 56 bachelor midwifery students, who had passed the theoretical and clinical courses of gynecology, were evaluated by Objective Structured Clinical Examination (OSCE. A demographic questionnaire and a standard checklist for writing the prescriptions and medications were used for data collection. SPSS Version 16 was used to carry out descriptive statistics. Findings: Most of the students were single, with the mean age of 23.0±1.7 years. Most errors were related to not recording the patients’ age and sex, diagnosis, chief complaint, and the prescriber’s name (observed in less than 10% of the prescriptions. The complete dosage schedule and drug name were stated only in 1.8±4.8 and 14±18.6 of prescriptions, respectively. In more than 93% of the cases, route of use and treatment duration were not recorded. Conclusion: According to the results, the number of prescription errors of midwifery students was high. Therefore, it is recommended to run educational courses on prescription writing skills (e.g. writing prescriptions based on World Health Organization (WHO guidelines for the midwifery students.

  15. Prescription of asthma medications before and during pregnancy in France

    DEFF Research Database (Denmark)

    Beau, Anna-Belle; Didier, Alain; Hurault-Delarue, Caroline;

    2016-01-01

    OBJECTIVE: Asthma affects between 3 to 8% of pregnant women. Previous studies have suggested that women's prescriptions for asthma medication change during pregnancy. The aim was to describe the prescription of asthma medications before and during pregnancy in France. METHODS: Women from the EFEM......OBJECTIVE: Asthma affects between 3 to 8% of pregnant women. Previous studies have suggested that women's prescriptions for asthma medication change during pregnancy. The aim was to describe the prescription of asthma medications before and during pregnancy in France. METHODS: Women from...

  16. Prescription analysis of pediatric outpatient practice in Nagpur city

    Directory of Open Access Journals (Sweden)

    Pandey Anuja

    2010-01-01

    Full Text Available Background: Medication errors are probably one of the most common types of medical errors, as medication is the most common health-care intervention. Knowing where and when errors are most likely to occur is generally felt to be the first step in trying to prevent these errors. Objective: To study prescribing patterns and errors in pediatric OPD prescriptions presenting to four community pharmacies across Nagpur city and to compare the prescription error rates across prescriber profiles. Materials and Methods: The study sample included 1376 valid pediatric OPD prescriptions presenting to four randomly selected community pharmacies in Nagpur, collected over a period of 2 months. Confirmed errors in the prescriptions were reviewed and analyzed. The core indicators for drug utilization studies, mentioned by WHO, were used to define errors. Results: The 1376 prescriptions included in the study were for a total of 3435 drugs, prescribed by 41 doctors. Fixed dose formulations dominated the prescribing pattern, many of which were irrational. Prescribing by market name was almost universal and generic prescriptions were for merely 254 (7.4% drugs. The prescribing pattern also indicated polypharmacy with the average number of drugs per encounter of 2.5. Antibiotics were included in 1087 (79% prescriptions, while injectable drugs were prescribed in 22 (1.6% prescriptions. The prescription error score varied significantly across prescriber profiles. Conclusion: The findings of our study highlight the continuing crisis of the irrational drug prescribing in the country.

  17. Mirror Prescription Regression: A Differential Interferometric Technique

    Directory of Open Access Journals (Sweden)

    Brian M. Robinson

    2010-01-01

    Full Text Available We present a remote, differential method for measuring the prescription of aspheric mirrors using null interferometry in the center-of-curvature configuration. The method requires no equipment beyond that used in a basic interferometery setup (i.e., there are no shearing elements or absolute distance meters. We chose this configuration because of its widespread use. However, the method is generalizable to other configurations with an adjustment of the governing equation. The method involves taking a series of interferograms before and after small, known misalignments are applied to the mirror in the interferometry setup and calculating the prescription (e.g., radius of curvature and conic constant of the mirror, based on these differential measurements, using a nonlinear regression. We apply this method successfully to the testing of a Space Optics Research Lab off-axis parabola with a known focal length of 152.4 mm, a diameter of 76.2 mm, and an off-axis angle of 12°.

  18. Quantitative Information on Oncology Prescription Drug Websites.

    Science.gov (United States)

    Sullivan, Helen W; Aikin, Kathryn J; Squiers, Linda B

    2016-09-02

    Our objective was to determine whether and how quantitative information about drug benefits and risks is presented to consumers and healthcare professionals on cancer-related prescription drug websites. We analyzed the content of 65 active cancer-related prescription drug websites. We assessed the inclusion and presentation of quantitative information for two audiences (consumers and healthcare professionals) and two types of information (drug benefits and risks). Websites were equally likely to present quantitative information for benefits (96.9 %) and risks (95.4 %). However, the amount of the information differed significantly: Both consumer-directed and healthcare-professional-directed webpages were more likely to have quantitative information for every benefit (consumer 38.5 %; healthcare professional 86.1 %) compared with every risk (consumer 3.1 %; healthcare professional 6.2 %). The numeric and graphic presentations also differed by audience and information type. Consumers have access to quantitative information about oncology drugs and, in particular, about the benefits of these drugs. Research has shown that using quantitative information to communicate treatment benefits and risks can increase patients' and physicians' understanding and can aid in treatment decision-making, although some numeric and graphic formats are more useful than others.

  19. Diabetic nephropathy: Prescription trends in tertiary care

    Directory of Open Access Journals (Sweden)

    Devi D

    2008-01-01

    Full Text Available Diabetic nephropathy is a leading cause of end stage renal disease. Drug utilization studies could promote rational drug use. The objective of this study was to evaluate prescribing trends in hospitalized patients with diabetic nephropathy. A prospective, observational study was conducted in a tertiary care hospital. The demographic, disease and treatment data of patients with diabetic nephropathy were collected for a period of six months and analysed. Drugs were classified using World Health Organization recommended Anatomic Therapeutic Chemical classification. A total of 755 drugs (7.4 drugs per prescription were prescribed to 102 study patients, who were all hypertensive and in late stages of diabetic nephropathy. Drug classes with largest representation were those acting on gastrointestinal tract plus metabolism (37% and cardiovascular drugs (28%. Calcium channel blockers represented the largest antihypertensive drug class (41%. Almost three-fourths of patients received more than one antihypertensive agent. Approximately 37% of patients did not receive any antidiabetic medication. Of those who did, prescriptions for insulin (91% exceeded those of oral hypoglycaemic drugs (9%. Antimicrobials accounted for 10.2% of all drugs prescribed, of which 31.8% were quinolones. Drugs prescribed by generic name accounted for 11.98%. While all patients received antihypertensive therapy, more than a third were not on any antidiabetic treatment. Antihypertensive poly-therapy was observed in the majority with calcium channel blockers being most frequently prescribed antihypertensive drug class. Insulin was the preferred to hypoglycaemic drugs.

  20. The NAL-NL2 prescription procedure

    Directory of Open Access Journals (Sweden)

    G. Keidser

    2011-03-01

    Full Text Available NAL-NL2 is the second generation of prescription procedures from The National Acoustic Laboratories (NAL for fitting wide dynamic range compression (WDRC instruments. Like its predecessor NALNL1 (Dillon, 1999, NAL-NL2 aims at making speech intelligible and overall loudness comfortable. This aim is mainly driven by a belief that these factors are most important for hearing aid users, but is also driven by the fact that less information is available about how to adjust gain to optimise other parameters that affect prescription such as localisation, tonal quality, detection of environmental sounds, and naturalness. In both formulas, the objective is achieved by combining a speech intelligibility model and a loudness model in an adaptive computer- controlled optimisation process. Adjustments have further been made to the theoretical component of NAL-NL2 that are directed by empirical data collected during the past decade with NAL-NL1. In this paper, the data underlying NAL-NL2 and the derivation procedure are presented, and the main differences from NAL-NL1 are outlined.

  1. How prescriptive norms influence causal inferences.

    Science.gov (United States)

    Samland, Jana; Waldmann, Michael R

    2016-11-01

    Recent experimental findings suggest that prescriptive norms influence causal inferences. The cognitive mechanism underlying this finding is still under debate. We compare three competing theories: The culpable control model of blame argues that reasoners tend to exaggerate the causal influence of norm-violating agents, which should lead to relatively higher causal strength estimates for these agents. By contrast, the counterfactual reasoning account of causal selection assumes that norms do not alter the representation of the causal model, but rather later causal selection stages. According to this view, reasoners tend to preferentially consider counterfactual states of abnormal rather than normal factors, which leads to the choice of the abnormal factor in a causal selection task. A third view, the accountability hypothesis, claims that the effects of prescriptive norms are generated by the ambiguity of the causal test question. Asking whether an agent is a cause can be understood as a request to assess her causal contribution but also her moral accountability. According to this theory norm effects on causal selection are mediated by accountability judgments that are not only sensitive to the abnormality of behavior but also to mitigating factors, such as intentionality and knowledge of norms. Five experiments are presented that favor the accountability account over the two alternative theories.

  2. Fertile ground? : soil fertility management and the African smallholder

    NARCIS (Netherlands)

    Misiko, M.

    2007-01-01

    Keywords: smallholder farmers, soil fertility, experimentation, "inconvenience", realist.The focus in this thesis is to form a view of how well soil fertility research performs within the ever shifting smallholder contexts. This study examined application of agro-ecological knowled

  3. Cancer treatment: fertility and sexual side effects in women

    Science.gov (United States)

    ... Alternative Names Radiotherapy - fertility; Radiation - fertility; Chemotherapy - fertility; Sexual dysfunction - cancer treatment References American Cancer Society. Fertility and women with cancer. Updated November 6, 2013. www.cancer. ...

  4. Women's education and fertility behaviour.

    Science.gov (United States)

    1993-12-01

    The education of women results in changes in women's health status, family well being, and fertility decline. The aim of human rights and social justice is also served by increasing women's educational levels. A review of the trends in developing countries has shown that there is a strong correlation between advanced female education (10 or more years) and lower fertility. Data for 26 countries was presented in table form for total fertility rates by years of education. There were many differences in the patterns of fertility by educational level based on country level of development. The data appeared to show stronger correlations between fertility and education in more prosperous societies; culture and social structure also influenced fertility. Partial primary education has been shown in some countries to be related to increased fertility. A UN study found a curvilinear relationship between fertility and education in 14 out of 38 countries with World Fertility Surveys. There were only 3 countries with Demographic and Health Surveys which showed the curvilinear pattern. The UN study confirmed that maternal education was related to shorter durations of postpartum abstinence and short durations of lactation. Caution was urged in interpreting that an increase in a few years of schooling in a dominant rural, illiterate population would facilitate rapid fertility decline. A critical threshold effect for educational attainment was found in mainly the least developed countries. Female education has direct and indirect effects on fertility. Education may affect breast feeding patterns, contraceptive use, social norms about small families, later age at marriage, and later age at first birth. The suggestion was that education provided for reproductive choice and reduces the gap between actual and desired family size. At the country and individual level of analysis, contraceptive use was linked with education. Effective contraceptive use was still however impeded by

  5. Alcohol and prescription drug safety in older adults

    Directory of Open Access Journals (Sweden)

    Zanjani F

    2013-02-01

    Full Text Available Faika Zanjani,1,2 Aasha I Hoogland,1 Brian G Downer11Department of Gerontology, 2Building Interdisciplinary Research Careers in Women's Health University of Kentucky, Lexington, KY, USABackground: The objectives of this study were to investigate older adults' knowledge of prescription drug safety and interactions with alcohol, and to identify pharmacists' willingness to disseminate prescription drug safety information to older adults.Methods: The convenience sample consisted of 48 older adults aged 54–89 years who were recruited from a local pharmacy and who completed surveys addressing their alcohol consumption, understanding of alcohol and prescription drug interactions, and willingness to change habits regarding alcohol consumption and prescription drugs. To address pharmacist willingness, 90 pharmacists from local pharmacies volunteered and answered questions regarding their willingness to convey prescription drug safety information to older adults.Results: Older adults reported low knowledge of alcohol and prescription drug safety, with women tending to be slightly more knowledgeable. More importantly, those who drank in the previous few months were less willing to talk to family and friends about how alcohol can have harmful interactions with prescription drugs, or to be an advocate for safe alcohol and prescription drug use than those who had not had a drink recently. Pharmacists reported that they were willing to convey prescription drug safety information to older adults via a variety of formats, including displaying or distributing a flyer, and directly administering a brief intervention.Conclusion: In this study, older adults were found to have inadequate knowledge of prescription drug safety and interactions with alcohol, but pharmacists who regularly come in contact with older adults indicated that they were ready and willing to talk to older adults about prescription drug safety. Future research should focus on interventions

  6. Prescription writing trends of antihistamines at the university health centre.

    Science.gov (United States)

    Kumar, Anil; Beenta

    2009-05-01

    The aim of the present study was to establish antihistamines drug prescribing pattern in order to improve the rational prescribing of antihistamines by physicians at Panjab University Health Centre. The study was performed in between the months of November 2005 to April 2006. Five hundred out patients were monitored and data was collected on WHO-based prescription-auditing performa. Demographic analysis of this prospective study revealed that out of the 500 patients, 293 (58.6 %) were male and 207 (41.4 %) were female and maximum patients were in the age group of 21-40 (34.8 %). Chlorpheniramine maleate (235 prescriptions) was the highest prescribed among antihistamine prescriptions (36.89 %) followed by diphenhydramine hydrochloride (186 prescriptions, 29.19%), cetirizine (175 prescriptions, 27.47 %) and promethazine (41 prescriptions, 6.4%). In comparison to generic drugs (169 prescriptions, 26.54%), branded were more prescribed at PUHC. Majority of antihistamines were in form of tablets (414 prescriptions, 64.99%) followed by liquid formulations (195 prescriptions, 30.61%) and injections (28 prescriptions, 4.40%). The average cost of different antihistamine drugs prescribed was as follows: diphenhydramine hydrochloride Rs. 34.74 followed by promethzine Rs. 22.46, chlorpheniramine maleate Rs. 15.30, and cetirizine Rs. 13.50. Average numbers of drugs prescribed per prescription were 1.27. The average consulting and dispensing time was 4.82 and 3.56 min, respectively. Out of the 500 university patients, 258 (51.6%) had the knowledge regarding the medication prescribed and 242 (48.4%) were unaware of the medication prescribed.

  7. Prescription writing trends of antihistamines at the university health centre

    Directory of Open Access Journals (Sweden)

    Kumar Anil

    2009-01-01

    Full Text Available The aim of the present study was to establish antihistamines drug prescribing pattern in order to improve the rational prescribing of antihistamines by physicians at Panjab University Health Centre. The study was performed in between the months of November 2005 to April 2006. Five hundred out patients were monitored and data was collected on WHO-based prescription-auditing performa. Demographic analysis of this prospective study revealed that out of the 500 patients, 293 (58.6 % were male and 207 (41.4 % were female and maximum patients were in the age group of 21-40 (34.8 %. Chlorpheniramine maleate (235 prescriptions was the highest prescribed among antihistamine prescriptions (36.89 % followed by diphenhydramine hydrochloride (186 prescriptions, 29.19%, cetirizine (175 prescriptions, 27.47 % and promethazine (41 prescriptions, 6.4%. In comparison to generic drugs (169 prescriptions, 26.54%, branded were more prescribed at PUHC. Majority of antihistamines were in form of tablets (414 prescriptions, 64.99% followed by liquid formulations (195 prescriptions, 30.61% and injections (28 prescriptions, 4.40%. The average cost of different antihistamine drugs prescribed was as follows: diphenhydramine hydrochloride Rs. 34.74 followed by promethzine Rs. 22.46, chlorpheniramine maleate Rs. 15.30, and cetirizine Rs. 13.50. Average numbers of drugs prescribed per prescription were 1.27. The average consulting and dispensing time was 4.82 and 3.56 min, respectively. Out of the 500 university patients, 258 (51.6% had the knowledge regarding the medication prescribed and 242 (48.4% were unaware of the medication prescribed.

  8. Multifunctional slow-release organic-inorganic compound fertilizer.

    Science.gov (United States)

    Ni, Boli; Liu, Mingzhu; Lü, Shaoyu; Xie, Lihua; Wang, Yanfang

    2010-12-08

    Multifunctional slow-release organic-inorganic compound fertilizer (MSOF) has been investigated to improve fertilizer use efficiency and reduce environmental pollution derived from fertilizer overdosage. The special fertilizer is based on natural attapulgite (APT) clay used as a matrix, sodium alginate used as an inner coating and sodium alginate-g-poly(acrylic acid-co-acrylamide)/humic acid (SA-g-P(AA-co-AM)/HA) superabsorbent polymer used as an outer coating. The coated multielement compound fertilizer granules were produced in a pan granulator, and the diameter of the prills was in the range of 2.5-3.5 mm. The structural and chemical characteristics of the product, as well as its efficiency in slowing the nutrients release, were examined. In addition, a mathematical model for nutrient release from the fertilizer was applied to calculate the diffusion coefficient D of nutrients in MSOF. The degradation of the SA-g-P(AA-co-AM)/HA coating was assessed by examining the weight loss with incubation time in soil. It is demonstrated that the product prepared by a simple route with good slow-release property may be expected to have wide potential applications in modern agriculture and horticulture.

  9. Menstrual cycle pattern and fertility

    DEFF Research Database (Denmark)

    Kolstad, Henrik A.; Bonde, Jens Peter; Hjøllund, Niels Henrik;

    1999-01-01

    To characterize how the menstrual cycle pattern relates to fertility regardless of potential biases caused by inappropriate coital timing during the menstrual cycle or early embryonal loss.......To characterize how the menstrual cycle pattern relates to fertility regardless of potential biases caused by inappropriate coital timing during the menstrual cycle or early embryonal loss....

  10. Family Systems and Fertility Intentions

    NARCIS (Netherlands)

    Mönkediek, Bastian; Bras, Hilde

    2017-01-01

    Family systems, as normative frameworks in which family processes unfold, are believed to exert a major influence on fertility. While a number of studies have addressed family system effects on family size and the timing of births, the question of how family systems influence fertility intentions

  11. ASSESSMENT OF PERCHLORATE IN FERTILIZERS

    Science.gov (United States)

    Perchlorate has been positively detected only in those materials known to be derived from Chilean caliche, which constitute less than 0.2% of U.S. fertilizer application. The data obtained in the preponderance of investigations suggest that fertilizers do not contribute to envir...

  12. Nanocomposites for controlled release of nitrogen fertilizer;Nanocompositos para liberacao controlada de fertilizantes nitrogenados

    Energy Technology Data Exchange (ETDEWEB)

    Silva, Viviane J.M. da; Visconte, Leila L.Y. [Universidade Federal do Rio de Janeiro (IMA/UFRJ), RJ (Brazil). Inst. de Macromoleculas Profa. Eloisa Mano; Matos, Talita S.; Lima, Erica S.A.; Polidoro, Jose Carlos [EMBRAPA Solos, RJ (Brazil); Nascimento, Regina Sandra V. [Universidade Federal do Rio de Janeiro (IQ/UFRJ), RJ (Brazil). Inst. de Quimica

    2009-07-01

    The study aimed at the development of nano structured materials capable of reducing the rate of release of nitrogen in the soil from an agricultural nitrogen fertilizer. Four different systems of polymer composites were prepared: (1) montmorillonite clay/fertilizer, (2) montmorillonite clay/thermoplastic starch and fertilizer, (3) montmorillonite clay/fertilizer, thermoplastic starch and low-density polyethylene (LDPE) and also (4) montmorillonite clay/fertilizer, thermoplastic starch and polycaprolactone. It was confirmed the formation of nano structured materials by elemental analysis (CHN) and X-ray diffraction (XRD). The kinetics of nitrogen release was detected by enzymatic colorimetric analysis and spectroscopy in the ultraviolet/visible. The results showed that all materials evaluated were able to reduce the rate of release of nitrogen in the fertilizers. (author)

  13. Children Procedures and Treatment (Fertility Issues)

    Medline Plus

    Full Text Available ... approach the subject of fertility preservation with their cancer-stricken child? How is the Oncofertility Consortium addressing the fertility preservation needs of children? How do cancer and cancer treatment affect a child's fertility? Why ...

  14. Children Procedures and Treatment (Fertility Issues)

    Medline Plus

    Full Text Available ... approach the subject of fertility preservation with their cancer-stricken child? How is the Oncofertility Consortium addressing the fertility preservation needs of children? How do cancer and cancer treatment affect a child's fertility? Why ...

  15. Internal fertilization in an oviparous frog.

    Science.gov (United States)

    Townsend, D S; Stewart, M M; Pough, F H; Brussard, P F

    1981-04-24

    Eleutherodactylus coqui, an oviparous frog, undergoes internal fertilization. If this mode of fertilization occurs in other species of anurans, interpretations of anuran reproductive strategies based on the assumption of external fertilization must be reviewed.

  16. [Thyroid gland and fertility].

    Science.gov (United States)

    Andreeva, P

    2014-01-01

    It is well-known that the thyroid hormones are associated with a number of aspects of the human reproduction. Both states, hyperthyroidism and hypothyroidism, have significant effect on the estrogen and androgen metabolism, the menstrual function and on fertility. The role of thyroid hormones (TH) during infertility has been little exploited. Interesting facts are that TH deficiency is more common in women with polycystic ovary syndrome (PCOS) and in certain cases with unexplained infertility. There are very few studies on the effect and paracrine regulation of TH and its receptors in the female reproductive tract. This report provides an overview of the most common thyroid disorders and their impact on ovarian function and reproductive performance in women as well as in cases with infertility and the implementation of assisted reproductive technologies (ART).

  17. Double fertilization in Helianthus

    Directory of Open Access Journals (Sweden)

    J. Telżyńska

    2015-01-01

    Full Text Available After controlled pollination of Helianthus annuus L. florets, the whole course of fertilization is described and documented on 24 microphotos. The timing of events is evaluated. The average cell cycle in the proembryo is 2 hours and the nuclear cycle in endosperm - 60 minutes.Plasmoptysis is suggested as the mechanism of pollen tube opening in the synergid. The structure of the thread-like sperm nucleus is interpreted as an end to end union of chromosomes, and the morphological changes of the sperm nuclei are explained as folding and coiling, based on a spiralization mechanism of chromosomes. Cytochemical observations indicating ribosome formation in the course of the nuclear cycles in the endosperm are described. The mechanisms accelerating nuclear cycles in the endosperm are discussed.

  18. 21 CFR 1306.06 - Persons entitled to fill prescriptions.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 9 2010-04-01 2010-04-01 false Persons entitled to fill prescriptions. 1306.06 Section 1306.06 Food and Drugs DRUG ENFORCEMENT ADMINISTRATION, DEPARTMENT OF JUSTICE PRESCRIPTIONS... either registered individually or employed in a registered pharmacy, a registered central fill pharmacy...

  19. 21 CFR 1306.22 - Refilling of prescriptions.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 9 2010-04-01 2010-04-01 false Refilling of prescriptions. 1306.22 Section 1306.22 Food and Drugs DRUG ENFORCEMENT ADMINISTRATION, DEPARTMENT OF JUSTICE PRESCRIPTIONS Controlled... pharmacy for a period of two years from the dispensing date. This printout of the day's controlled...

  20. Pharmaceutical interventions on prescription problems in a Danish pharmacy setting

    DEFF Research Database (Denmark)

    Pottegård, Anton; Hallas, Jesper; Søndergaard, Jens

    2011-01-01

    International studies regarding pharmacists' interventions towards prescription problems produce highly variable results. The only peer-reviewed study in a Danish setting estimated an intervention rate of 2.3 per 1,000 prescriptions. With the introduction of a new tool for registration, we hypoth...

  1. Relationship between e-prescriptions and community pharmacy workflow.

    Science.gov (United States)

    Odukoya, Olufunmilola K; Chui, Michelle A

    2012-01-01

    To understand how community pharmacists use electronic prescribing (e-prescribing) technology and to describe the workflow challenges pharmacy personnel encounter as a result of using e-prescribing technology. Cross-sectional qualitative study. Seven community pharmacies in Wisconsin from December 2010 to March 2011. 16 pharmacists and 14 pharmacy technicians (in three chain and four independent pharmacies). Think-aloud protocols and pharmacy group interviews. Pharmacy staff descriptions of their use of e-prescribing technology and challenges encountered in their daily workflow related to this technology. Two contributing factors were perceived to influence e-prescribing workflow: issues stemming from prescribing or transmitting software and issues from within the pharmacy. Pharmacies experienced both delayed and inaccurate e-prescriptions from physician offices. An overwhelming number of e-prescriptions with inaccurate or unclear information resulted in serious time delays for patients as pharmacists contacted physicians to clarify wrong information. In addition, lack of formal training and the disconnect between pharmacy procedures for verifying prescription accuracy and presentation of e-prescription information on the computer screen influenced the speed of processing an e-prescription. E-prescriptions processing can hinder pharmacy workflow. As the number of e-prescriptions transmitted to pharmacies increases because of legislative mandates, it is essential that the technology supporting e-prescriptions (both on the prescriber and pharmacy operating systems) be redesigned to facilitate pharmacy workflow processes and to prevent unintended increase in medication errors, user frustration, and stress.

  2. Prescriptive Profile Procedure for Children With Learning Disabilities.

    Science.gov (United States)

    Levine, Eleanor; Fineman, Carol

    The Prescriptive Profile Procedure (PPP) attempts to provide teachers of learning disabled elementary school children with a procedure of individualized diagnosis and educational prescription which encompasses strengths and weaknesses in prerequisite skills, basic school subjects, and behavioral factors. A competency statement and six to 12…

  3. Asthma prescription patterns for children: can GPs do better?

    NARCIS (Netherlands)

    Uijen, J.H.J.M.; Wouden, J.C. van der; Schellevis, F.G.; Willemsen, S.P.; Suijlekom-Smit, L.W.A. van; Bindels, P.J.E.

    2011-01-01

    Background: Assessing prescription patterns of asthma medication for children is helpful to optimize prescribing by general practitioners (GPs). The aim was to explore prescription patterns in children with physician-diagnosed asthma and its determinants in general practice. Methods: We used the Sec

  4. Prescription Drug Abuse Information in D.A.R.E.

    Science.gov (United States)

    Morris, Melissa C.; Cline, Rebecca J. Welch; Weiler, Robert M.; Broadway, S. Camille

    2006-01-01

    This investigation was designed to examine prescription drug-related content and learning objectives in Drug Abuse Resistance Education (D.A.R.E.) for upper elementary and middle schools. Specific prescription-drug topics and context associated with content and objectives were coded. The coding system for topics included 126 topics organized…

  5. [Failure mode and effects analysis on computerized drug prescriptions].

    Science.gov (United States)

    Paredes-Atenciano, J A; Roldán-Aviña, J P; González-García, Mercedes; Blanco-Sánchez, M C; Pinto-Melero, M A; Pérez-Ramírez, C; Calvo Rubio-Burgos, Miguel; Osuna-Navarro, F J; Jurado-Carmona, A M

    2015-01-01

    To identify and analyze errors in drug prescriptions of patients treated in a "high resolution" hospital by applying a Failure mode and effects analysis (FMEA).Material and methods A multidisciplinary group of medical specialties and nursing analyzed medical records where drug prescriptions were held in free text format. An FMEA was developed in which the risk priority index (RPI) was obtained from a cross-sectional observational study using an audit of the medical records, carried out in 2 phases: 1) Pre-intervention testing, and (2) evaluation of improvement actions after the first analysis. An audit sample size of 679 medical records from a total of 2,096 patients was calculated using stratified sampling and random selection of clinical events. Prescription errors decreased by 22.2% in the second phase. FMEA showed a greater RPI in "unspecified route of administration" and "dosage unspecified", with no significant decreases observed in the second phase, although it did detect, "incorrect dosing time", "contraindication due to drug allergy", "wrong patient" or "duplicate prescription", which resulted in the improvement of prescriptions. Drug prescription errors have been identified and analyzed by FMEA methodology, improving the clinical safety of these prescriptions. This tool allows updates of electronic prescribing to be monitored. To avoid such errors would require the mandatory completion of all sections of a prescription. Copyright © 2014 SECA. Published by Elsevier Espana. All rights reserved.

  6. Prosthetic prescription in the Netherlands: An observational study

    NARCIS (Netherlands)

    Van Der Linde, H.; Geertzen, J.H.B.; Hofstad, C.J.; Van Limbeek, J.; Postema, K.

    2003-01-01

    Prosthetic prescription for lower limb amputees and the methodology used are primarily based on empirical knowledge. Clinical expertise plays an important role that can lead to an adequate prescription; however, a clear evidence based motivation for the choices made cannot be given. This can lead to

  7. Pattern of prescription drug use in Nigerian army hospitals

    African Journals Online (AJOL)

    To our knowledge, only few studies have been done in Africa on this issue , with inadequate ... high number of drugs per prescription, high rate of antibiotic usage and unscientific prescription by doctors. ..... the managers of Nigerian public health institutions through the ... use promotes drug resistance, increases risk of side.

  8. Preventing Prescription Drug Abuse in Adolescence: A Collaborative Approach

    Science.gov (United States)

    Jones, Beth A.; Fullwood, Harry; Hawthorn, Melissa

    2012-01-01

    With the growing awareness of adolescent prescription drug abuse, communities and schools are beginning to explore prevention and intervention strategies which are appropriate for their youth. This article provides a framework for developing a collaborative approach to prescription drug abuse prevention--called the Prevention Awareness Team--that…

  9. Asthma prescription patterns for children: can GPs do better?

    NARCIS (Netherlands)

    Uijen, J.H.J.M.; Wouden, J.C. van der; Schellevis, F.G.; Willemsen, S.P.; Suijlekom-Smit, L.W.A. van; Bindels, P.J.E.

    2011-01-01

    Background: Assessing prescription patterns of asthma medication for children is helpful to optimize prescribing by general practitioners (GPs). The aim was to explore prescription patterns in children with physician-diagnosed asthma and its determinants in general practice. Methods: We used the

  10. 21 CFR 202.1 - Prescription-drug advertisements.

    Science.gov (United States)

    2010-04-01

    ...) DRUGS: GENERAL PRESCRIPTION DRUG ADVERTISING § 202.1 Prescription-drug advertisements. (e) * * * (6... drug, nor may an advertisement contain a quantitative statement of safety or effectiveness (a) unless... effectiveness is supported by substantial evidence derived from adequate and well-controlled studies as defined...

  11. Overview of Four Prescription Monitoring/Review Programs in Canada

    Directory of Open Access Journals (Sweden)

    Andrea D Furlan

    2014-01-01

    Full Text Available BACKGROUND: Prescription monitoring or review programs collect information about prescription and dispensing of controlled substances for the purposes of monitoring, analysis and education. In Canada, it is the responsibility of the provincial institutions to organize, maintain and run such programs.

  12. Recognizing Signs of Prescription Drug Abuse and Addiction, Part I.

    Science.gov (United States)

    Felicilda-Reynaldo, Faye D

    2014-01-01

    Prescription drug abuse/misuse is increasing. Nonmedical use of prescription medications, especially opioid analgesics, now is considered an epidemic in the United States. Medical-surgical nurses are in a strategic position to help address substance abuse problems in patients.

  13. EXERCISE ON PRESCRIPTION AUDIT : A TOOL FOR PHARMACOLOGY PRACTICAL LESSON

    Directory of Open Access Journals (Sweden)

    Supreeti Biswas

    2012-07-01

    Full Text Available To improve the understanding and perception about rational prescribing among the Undergraduate (UG students, a record based study 'exercise on prescription audit' was undertaken as self-directed learning strategy. Study was conducted on Objectively Structured Evaluation of pharmacotherapy taking one year record of prescriptions in Bed Head Tickets (BHTs of discharged Ophthalmic in-patients. Standard format for prescription writing, WHO guide to Good prescribing and Essential Medicines were followed to assess the in-patient prescriptions. Students improved markedly (p< 0.001 in audit of real prescriptions. Results revealed that 37 types of drugs were prescribed over 948 BHTs. Completeness of the prescription showed 100% perfection in maximum indicators with exception in judicious investigations (99.89%, medication information (89.32% and relevant advices for patient (97.12%. Subsidiary or symptomatic drugs (56.76% were prescribed more than the core drugs (43.24% of total drugs prescribed. Generic prescription was 54.05%. Study in turn improved the understanding and perception about rational prescribing among the students. The students gained knowledge about the utilization of different types of dosage forms of drugs. Prescription audit as self-directed learning must be a tool for practical lesson of Pharmacology for UG-course as well as for PG-curriculum.

  14. Nonmedical Prescription Drug Use among Midwestern Rural Adolescents

    Science.gov (United States)

    Park, Nicholas K.; Melander, Lisa; Sanchez, Shanell

    2016-01-01

    Prescription drug misuse has been an increasing problem in the United States, yet few studies have examined the protective factors that reduce risk of prescription drug abuse among rural adolescents. Using social control theory as a theoretical framework, we test whether parent, school, and community attachment reduce the likelihood of lifetime…

  15. 77 FR 8174 - EPAAR Prescription for Work Assignments

    Science.gov (United States)

    2012-02-14

    ... revised language communicates to contract personnel and program staff that government cost-related... (EPA). ACTION: Final rule. SUMMARY: EPA will amend the EPA Acquisition Regulation (EPAAR) prescription for the work assignment clause. This final rule provides revised language to the prescription for the...

  16. 76 FR 26232 - EPAAR Prescription for Work Assignments

    Science.gov (United States)

    2011-05-06

    ... Acquisition Regulation (EPAAR) to update policy, procedures, and contract clauses. The proposed rule provides revised language to the prescription for the work assignment clause, incorporating prescriptive language that provides further instructions on use of the related clause. DATES: Comments must be received on or...

  17. Do Physicians Change Prescription Practice in Response to Financial Incentives?

    Science.gov (United States)

    Park, Sylvia; Han, Euna

    2016-07-01

    We assessed the impact on physician prescription behaviors of an outpatient prescription incentive program providing financial rewards to primary care physicians for saving prescription costs in South Korea. A 10% sample of clinics (N = 1,625) was randomly selected from all clinics in the National Health Insurance claims database for the years 2009-2012, and all claims with the primary diagnosis of peptic ulcer or gastro-esophageal reflux diseases were extracted from those clinics' data. A clinic-level random-effects model was used. After the program, clinics in general medicine showed a lower prescription rate (by 0.8 percentage points), lower number of medicines prescribed (by 0.02), lower prescription duration (by 0.15 days), and lower drug expenditure per claim (by 740 won). Small clinics on the <25th percentile of a regional sum of monthly drug expenditure had shorter prescription duration (by 0.76 days), while large clinics on the ≥75th percentile and clinics in group practice had a higher prescription rate (by 1.5 and 2.5 percentage points, respectively) and a higher number of medicines prescribed (by 0.03 for group practice only) after the program. The outpatient prescription incentive program worked as intended only in certain subgroup clinics for the target medicines.

  18. Controversy in Purchasing Prescription Drugs Online in China.

    Science.gov (United States)

    Yuan, Peng; Qi, Lin; Wang, Long

    2016-08-01

    China's government is considering legalization of online prescription drugs to increase the pharmaceutical market and enhance access to necessary medicines. However, challenges such as a shortage of licensed pharmacists and drug quality issues have raised concerns and delayed consensus on the proposal. China's government must address the most pressing issues so it can render a decision on online prescription sales.

  19. 77 FR 20637 - Request for Information on Prescription Medication Adherence

    Science.gov (United States)

    2012-04-05

    ... HUMAN SERVICES Request for Information on Prescription Medication Adherence AGENCY: Department of Health... potential solutions associated with the public health problem of prescription medication non-adherence in..., health care providers, and industry and private organizations in efforts to improve medication...

  20. Prosthetic prescription in the Netherlands : an observational study

    NARCIS (Netherlands)

    van der Linde, H; Geertzen, JHB; Hofstad, CJ; Postema, K

    2003-01-01

    Prosthetic prescription for lower limb amputees and the methodology used are primarily based on empirical knowledge. Clinical expertise plays an important role that can lead to an adequate prescription; however, a clear evidence based motivation for the choices made cannot be given. This can lead to

  1. Migrant fertility differentials in Ecuador.

    Science.gov (United States)

    Rundquist, F; Brown, L A

    1989-01-01

    The effects of migration on fertility in Ecuador were analyzed by subdividing migrant categories into permanent-, return-, circular-, and non-migrants, and context factors into 6 socioeconomic and agrarian variables. The study is introduced with a conceptual framework that explains personal intermediate variables and their influence on fertility in terms of demographic transition theory, and then defines the influences of selection for fertility, disruption of marital unions, and socialization into fertility norms at the origin vs. assimilation of norms at the destination. Migrants are usually better educated, younger and upwardly mobile, all selecting for lower fertility. Migration disrupts formation of marital unions, and causes separation of spouses, lowering fertility. Data for this study were from the 1974 and 1982 Ecuadorian Population Censuses. The contextual variables analyzed were urban/rural; manufacturing/agricultural; mineral extraction/economic recession; long/recent agricultural settlement; domestic/export crop; and large/medium sized farm. The analysis of personal attributes showed that fertility increased over the range on non-migrants through circular-, return- to permanent-migrants, a finding explained by degrees of disruption of unions. Higher fertility was associated with less education, lower economic participation, higher prevalence of marriage, longer residence and older ages. Regression analysis also showed that personal attributes outweighed contextual factors: thus age, marriage rates, residence time, education and economic activity were significant. Contextual factors were important only for non-migrants, except for destination variables which affected return-migrants and origin variables which affected circular-migrants. Low fertility was associated with urbanization, industrialization, mineral extraction, large farms, recent farm settlement and export crops. The results indicate cear influences of modernity and place influences on

  2. Prescription Drug Monitoring Programs and Other Interventions to Combat Prescription Opioid Abuse

    Directory of Open Access Journals (Sweden)

    Bharath Chakravarthy

    2012-12-01

    Full Text Available The Center for Disease Control and Prevention (CDC has published significant data and trendsrelated to opioid prescription pain relievers (OPR. In 2008, 20,044 deaths were attributedto prescription drug overdose of which 14,800 (73.8% were due to OPR, an amount greaterthan the number of overdose deaths from heroin and cocaine combined. The majority of thesedeaths were unintentional. Between 1999-2008, overdose deaths from OPR increased almostfour-fold. Correspondingly, sales of OPR were four times greater in 2010 than in 1999. Mostsignificant to emergency physicians is the estimate that 39% of all opioids prescribed, administeredor continued come from the emergency department (ED. We present findings from theCDC’s Morbidity and Mortality Weekly Report (MMWR with commentary on current recommendationsand policies for curtailing the OPR epidemic.1

  3. The appropriateness of a proton pump inhibitor prescription.

    LENUS (Irish Health Repository)

    Moran, N

    2014-11-01

    Proton pump inhibitors (PPIs) are one of the most commonly prescribed groups of drug in Ireland, at great expense to the Irish healthcare executive. This study aims to evaluate the appropriateness of PPI prescriptions on admission and discharge in a tertiary referral hospital. All non-elective admissions in the Emergency Department in one week were included in the study. 102 patients in total were included, with 36 (35.4%) treated with a PPI on admission. Of these, only 3 (8.3%) had a clear indication noted as per current NICE guidelines. 18 new in-hospital PPI prescriptions were documented. 11 (61%) of which were present on discharge prescriptions. Continuing PPI prescription on discharge into the community may be inappropriate, costly and potentially harmful. Brief interventions aimed at reducing inappropriate PPI prescriptions have been shown to be effective at reducing the cost and potential harm of unnecessary treatment.

  4. Delayed antibiotic prescriptions for respiratory infections.

    Science.gov (United States)

    Spurling, Geoffrey Kp; Del Mar, Chris B; Dooley, Liz; Foxlee, Ruth; Farley, Rebecca

    2017-09-07

    Concerns exist regarding antibiotic prescribing for respiratory tract infections (RTIs) owing to adverse reactions, cost, and antibacterial resistance. One proposed strategy to reduce antibiotic prescribing is to provide prescriptions, but to advise delay in antibiotic use with the expectation that symptoms will resolve first. This is an update of a Cochrane Review originally published in 2007, and updated in 2010 and 2013. To evaluate the effects on clinical outcomes, antibiotic use, antibiotic resistance, and patient satisfaction of advising a delayed prescription of antibiotics in respiratory tract infections. For this 2017 update we searched the Cochrane Central Register of Controlled Trials (CENTRAL) (the Cochrane Library, Issue 4, 2017), which includes the Cochrane Acute Respiratory Infection Group's Specialised Register; Ovid MEDLINE (2013 to 25 May 2017); Ovid Embase (2013 to 2017 Week 21); EBSCO CINAHL Plus (1984 to 25 May 2017); Web of Science (2013 to 25 May 2017); WHO International Clinical Trials Registry Platform (1 September 2017); and ClinicalTrials.gov (1 September 2017). Randomised controlled trials involving participants of all ages defined as having an RTI, where delayed antibiotics were compared to immediate antibiotics or no antibiotics. We defined a delayed antibiotic as advice to delay the filling of an antibiotic prescription by at least 48 hours. We considered all RTIs regardless of whether antibiotics were recommended or not. We used standard Cochrane methodological procedures. Three review authors independently extracted and collated data. We assessed the risk of bias of all included trials. We contacted trial authors to obtain missing information. For this 2017 update we added one new trial involving 405 participants with uncomplicated acute respiratory infection. Overall, this review included 11 studies with a total of 3555 participants. These 11 studies involved acute respiratory infections including acute otitis media (three studies

  5. How do community pharmacies recover from e-prescription errors?

    Science.gov (United States)

    Odukoya, Olufunmilola K; Stone, Jamie A; Chui, Michelle A

    2014-01-01

    The use of e-prescribing is increasing annually, with over 788 million e-prescriptions received in US pharmacies in 2012. Approximately 9% of e-prescriptions have medication errors. To describe the process used by community pharmacy staff to detect, explain, and correct e-prescription errors. The error recovery conceptual framework was employed for data collection and analysis. 13 pharmacists and 14 technicians from five community pharmacies in Wisconsin participated in the study. A combination of data collection methods were utilized, including direct observations, interviews, and focus groups. The transcription and content analysis of recordings were guided by the three-step error recovery model. Most of the e-prescription errors were detected during the entering of information into the pharmacy system. These errors were detected by both pharmacists and technicians using a variety of strategies which included: (1) performing double checks of e-prescription information; (2) printing the e-prescription to paper and confirming the information on the computer screen with information from the paper printout; and (3) using colored pens to highlight important information. Strategies used for explaining errors included: (1) careful review of patient's medication history; (2) pharmacist consultation with patients; (3) consultation with another pharmacy team member; and (4) use of online resources. In order to correct e-prescription errors, participants made educated guesses of the prescriber's intent or contacted the prescriber via telephone or fax. When e-prescription errors were encountered in the community pharmacies, the primary goal of participants was to get the order right for patients by verifying the prescriber's intent. Pharmacists and technicians play an important role in preventing e-prescription errors through the detection of errors and the verification of prescribers' intent. Future studies are needed to examine factors that facilitate or hinder recovery

  6. How do Community Pharmacies Recover from E-prescription Errors?

    Science.gov (United States)

    Odukoya, Olufunmilola K.; Stone, Jamie A.; Chui, Michelle A.

    2014-01-01

    Background The use of e-prescribing is increasing annually, with over 788 million e-prescriptions received in US pharmacies in 2012. Approximately 9% of e-prescriptions have medication errors. Objective To describe the process used by community pharmacy staff to detect, explain, and correct e-prescription errors. Methods The error recovery conceptual framework was employed for data collection and analysis. 13 pharmacists and 14 technicians from five community pharmacies in Wisconsin participated in the study. A combination of data collection methods were utilized, including direct observations, interviews, and focus groups. The transcription and content analysis of recordings were guided by the three-step error recovery model. Results Most of the e-prescription errors were detected during the entering of information into the pharmacy system. These errors were detected by both pharmacists and technicians using a variety of strategies which included: (1) performing double checks of e-prescription information; (2) printing the e-prescription to paper and confirming the information on the computer screen with information from the paper printout; and (3) using colored pens to highlight important information. Strategies used for explaining errors included: (1) careful review of patient’ medication history; (2) pharmacist consultation with patients; (3) consultation with another pharmacy team member; and (4) use of online resources. In order to correct e-prescription errors, participants made educated guesses of the prescriber’s intent or contacted the prescriber via telephone or fax. When e-prescription errors were encountered in the community pharmacies, the primary goal of participants was to get the order right for patients by verifying the prescriber’s intent. Conclusion Pharmacists and technicians play an important role in preventing e-prescription errors through the detection of errors and the verification of prescribers’ intent. Future studies are needed

  7. Researches on Fertilization of Camellia Oleifera%油茶施肥研究进展

    Institute of Scientific and Technical Information of China (English)

    许鹏波; 薛立

    2011-01-01

    科学施肥是实现油茶优质高产的一个重要措施.施肥可以提高油茶的净光合速率、水分利用率、气孔导度,从而明显促进油茶生长,提高产量.配方施肥对油茶幼树的营养生长有显著的促进作用.施用N和P肥可以提高叶片P浓度、N矿质化速率、森林地表的养分供应和微生物活性,从而促进树木生长;油茶肥料主要有基肥和追肥,主要通过沟施和叶面喷施施用,春季和初夏为有效的施肥季节.油茶施肥今后的研究方向包括使肥料效应函数法变的简单实用,将以3S技术为支撑的林木营养管理信息系统应用于油茶施肥,研究和生产油茶的专用肥和缓控释肥.%Reasonable fertilization is an important measure for high yield of Camellia oleifera with good quality. Fertilization can enhance photosynthesis rate, water using efficiency and stomatal conductance, so that growth and yield of C. oleifera are promoted. Prescription fertilization significantly improves vegetative growth of young C. oleifera trees. Tree growth, foliar P concentrations, N mineralization rate, nutrient supply and microbial activity may be improved after addition of N + P fertilizer. Fertilizer species of C. oleifera include base fertilizer and top dressing, which are fertilized by furrow application and leaf spraying, and spring and early summer are effect fertilization seasons. Future research of C. oleifera fertilization will focus on developing a simple and practical fertilizer response function, applying management information system supported with 3S technology on C. oleifera fertilization, research and production of C. oleifera-specific fertilizer and slow/controlled released fertilizer.

  8. [Impact of a quality control program on antibiotic prescription in a hospital in Havana, Cuba].

    Science.gov (United States)

    Guanche Garcell, Humberto; Pisonero Socias, Juan José; Enseñat Sánchez, Raimy; Fiterre Lancis, Irene; Mir Narbona, Ioanna; García Arzola, Belkis; Pardo Gómez, Gilberto; Gutiérrez García, Francisco

    2011-12-01

    Demonstrate the efficacy of a quality control program on antibiotic prescription in Joaquín Albarrán Hospital in Havana, Cuba. An interventional study was conducted from 1 May 2008 to 31 March 2011. The study included evaluation of prescription quality, information feedback, educational activities, the operations of an antibiotic committee, and the preparation of protocols on antimicrobial drug use. A simple arithmetic graph of the time series was constructed, and the absolute values of the series percentages were compared. In order to verify the existence of a series trend, a simple linear regression model was applied. Antibiotic prescription was evaluated in 2 941 patients. An irregular series was observed, with inappropriate use in 30.7%-48.4% of these patients in the first three months analyzed. The value of the regression slope was close to zero, although it was negative and significantly different from zero (β = -0.29; P = 0.02). The antibiotic control program improved the quality of prescribing for hospital patients.

  9. Technology of Mg(OH)2 Preparation Using Magnesium Resource from the Byproduct of Potassium Fertilizer Production%钾肥副产镁资源制备氢氧化镁的生产技术

    Institute of Scientific and Technical Information of China (English)

    吴礼定; 曾波

    2012-01-01

    氢氧化镁是一种重要的无机化工原料,其用途广泛,市场广阔.青海盐湖蕴藏着十分丰富的镁资源,盐湖集团钾肥生产中每吨产品氯化钾排放母液(俗称老卤)30t,可副产10t氯化镁.文章介绍了目前中国利用盐湖镁资源制备氢氧化镁的方法,包括物理粉碎法、氢氧化钙法、氨法、氢氧化钠法、组合法等,简要分析了这些方法的优缺点.提出了开发利用钾盐伴生的镁资源,扩大镁的来源,提升中国氢氧化镁的市场竞争能力.%Magnesium hydroxide is a kind of important inorganic chemical with versatile application and wide market. There are plenty of magnesium resources in Qinghai Salt Lake. When 1 ton potassium chloride is produced in production, 30 tons mother liquor (old halogm) discharge, which can produce 10 tons magnesium chloride. Preparation methods of magnesium hydroxide in China including physical mill, calcium chloride, ammonia, sodium hydroxide, combination method ect. Are introduced in magnesium resources utilization. And the advantage and the disadvantage of the methods are also analyzed. The magnesium resource from the byproduct of potassium production can be developed and utilized to increase the source of magnesium. The market competitive force of magnesium hydroxide will be improved.

  10. Research Progress in the Effect and Mechanism of Fertilization Measures on Soil Fertility

    Institute of Scientific and Technical Information of China (English)

    Dongfeng; HUANG; Limin; WANG; Weihua; LI; Xiaoxuan; QIU

    2015-01-01

    This paper firstly summarized the domestic and foreign research progress in the relationship between fertilization measures and soil fertility. It elaborated the relationship between fertilization measures and basic physical and chemical properties,soil enzyme activity,soil microorganism fertility index,and soil animal fertility index. It pointed out future researches about the relationship between fertilization measures and soil fertility include:( i) the relationship between fine and high efficient input of organic fertilizer and soil fertility,( ii) in-depth research of soil zoology fertility index,( iii) soil biology about long-term fertilization,and( iv) soil fertilization and agricultural diffused pollution. It is intended to provide scientific reference for improving farmland soil fertility and maintaining excellent ecological environment of farmland through proper fertilization measures.

  11. Identification and management of prescription drug abuse in pregnancy.

    Science.gov (United States)

    Worley, Julie

    2014-01-01

    Prescription drug abuse is a growing problem in the United States and many other countries. Estimates of prescription drug abuse rates during pregnancy range from 5% to 20%. The primary prescription drugs designated as controlled drugs with abuse potential in pregnancy are opiates prescribed for pain, benzodiazepines prescribed for anxiety, and stimulants prescribed for attention-deficit/hyperactivity disorder. Prescription drugs are obtained for abuse through diversion methods, such as purchasing them from others or by doctor shopping. The use of prescription drugs puts both the mother and the fetus at high risk during pregnancy. Identification of women who are abusing prescription drugs is important so that treatment can be ensured. It is crucial for healthcare professionals to use a multidisciplinary approach and be supportive and maintain a good rapport with pregnant women who abuse prescription drugs. Management includes inpatient hospitalization for detoxification and withdrawal symptoms, and in the case of opiate abuse, opiate maintenance is recommended for pregnant women for the duration of their pregnancy to reduce relapse rates and improve maternal and fetal outcomes. Other recommendations include referral for support groups and supportive housing.

  12. Prescription-induced jump distributions in multiplicative Poisson processes

    Science.gov (United States)

    Suweis, Samir; Porporato, Amilcare; Rinaldo, Andrea; Maritan, Amos

    2011-06-01

    Generalized Langevin equations (GLE) with multiplicative white Poisson noise pose the usual prescription dilemma leading to different evolution equations (master equations) for the probability distribution. Contrary to the case of multiplicative Gaussian white noise, the Stratonovich prescription does not correspond to the well-known midpoint (or any other intermediate) prescription. By introducing an inertial term in the GLE, we show that the Itô and Stratonovich prescriptions naturally arise depending on two time scales, one induced by the inertial term and the other determined by the jump event. We also show that, when the multiplicative noise is linear in the random variable, one prescription can be made equivalent to the other by a suitable transformation in the jump probability distribution. We apply these results to a recently proposed stochastic model describing the dynamics of primary soil salinization, in which the salt mass balance within the soil root zone requires the analysis of different prescriptions arising from the resulting stochastic differential equation forced by multiplicative white Poisson noise, the features of which are tailored to the characters of the daily precipitation. A method is finally suggested to infer the most appropriate prescription from the data.

  13. [Inappropriate prescription in older patients: the STOPP/START criteria].

    LENUS (Irish Health Repository)

    Delgado Silveira, Eva

    2009-09-01

    Older people are a heterogeneous group of patients, often with multiple comorbidities for which they are prescribed a large number of drugs, leading to an increased risk of adverse drug reactions (ADR) and drug interactions. This risk is compounded by physiological age-related changes in physiology, changes in drug pharmacokinetics and pharmacodynamics, as well as by disease-related, functional and social issues. Inappropriate prescription of drugs is common in the older individuals and contributes to the increased risk of ADR. Several tools have been developed to detect potentially inappropriate prescription, the most frequently used in Spain being Beers\\' criteria. However, the value of these criteria is limited, especially as they were developed in a different healthcare system. In this article, the Spanish version of a new tool to detect potentially inappropriate prescriptions-STOPP (Screening Tool of Older Person\\'s Prescriptions) and START (Screening Tool to Alert doctors to Right i.e. appropriate, indicated Treatment) criteria-is presented. The creation, development, reliability, and use of these criteria in routine practice is described and discussed. These criteria have shown better sensitivity than Beers\\' criteria in detecting prescription problems and have the added value of being able to detect not only inappropriate prescription of some drugs, but also the omission of well indicated drugs. The STOPP\\/START criteria could become a useful screening tool to improve prescription in older people.

  14. Influence of pharmaceutical marketing on prescription practices of physicians.

    Science.gov (United States)

    Narendran, Roshni; Narendranathan, M

    2013-01-01

    In India same drug molecules are sold under different brand names by different pharmaceuticals. To persuade the physicians to prescribe their brands pharmaceuticals engage in marketing techniques like giving samples, gifts, sponsoring travel etc. Many countries are striving to reduce the impact of incentives on prescription behaviour. This study explores the influence of pharmaceutical marketing on the prescription practices of doctors in India. There were 103 study subjects - 50 doctors and 53 sales personnel. Data collection was done by a self administered questionnaire. Data were collected on 36 variables which were supposed to influence prescription. The effectiveness of the promotional strategies on prescription behaviour was marked in a seven point Likert scale ranging from "not at all effective" (score=1) to "extremely effective" (score=7). Open ended questions were used to collect qualitative data. Good rapport with the doctor, launch meetings, reputation of the company, quality of the drug and brand names significantly influenced prescription behaviour, while direct mailers, advertisements in journals and giving letter pads and other brand reminders were less effective. Commonly used method of giving samples was not among the twenty most effective methods influencing prescription. Product quality and good company are still factors that influence prescription. Pharmaceutical marketing influences the choice of brands by a physician. The more expensive strategies involved in public relations are more effective. Sending mails and journal advertisements are less effective strategies. How expensive marketing strategies affect cost of the medicines has to be explored further.

  15. [Prolactin and male fertility].

    Science.gov (United States)

    Schreiber, G; Börner, A; Lauterbach, H; Thiel, W

    1983-03-01

    On 68 selected patients with disturbances of the potentia generandi et/sive coeundi (25 males with healthy metabolism and 43 males with diabetes) as well as 14 control persons PRL, LH, FSH, testosterone and oestradiol were determined radioimmunologically and the results were ascribed to sexological, clinical, spermatological and testo-histological findings. A statistically secure correlation was found between PRL values and disturbance of the libido as well as the presence of a gynaecomasty. PRL did not correlate with the spermatological variables volume of ejaculate, relative and absolute number of spermatozoa and motility. PRL did also not correlate with the testohistological findings. A relation between PRL and the peptide hormones LH and FSH as well as the steroid hormones testosterone and oestradiol could not be ascertained. Therefore the diagnostic values of a PRL determination is much limited; the pertinency of a hyperprolactinaemia may be increased by the proof of the symptoms reduction of libido and gynaecomasty with simultaneous disturbance of fertility. In our opinion the definition of hyperprolactinaemia needs revision, since at only determination of the basal value of more than 800 mU/l no more frequently pathologically andrological findings are to be observed than below 200 mU/l.

  16. Fertilization of SRC willow. II

    DEFF Research Database (Denmark)

    Sevel, L; Ingerslev, Morten; Nord-Larsen, Thomas

    2014-01-01

    Short rotation coppice (SRC) willow is an emerging cropping system in focus for production of biomass for energy. To increase production, the willow is commonly fertilized, but studies have shown differing effects of fertilization on biomass production, ranging from almost no response...... impacts of different doses of mineral fertilizer, manure and sewage sludge in a commercially grown SRC willow stand. We examined macro nutrient and heavy metal leaching rates and calculated element balances to evaluate the environmental impact. Growth responses were reported in a former paper (Sevel et al....... “Fertilization of SRC Willow, I: Biomass Production Response” Bioenergy Research, 2013). Nitrogen leaching was generally low, between 1 and 7 kg N ha−1 year−1 when doses of up to 120 kg N ha−1 year−1 were applied. Higher doses of 240 and 360 kg N ha−1 as single applications caused leaching of 66 and 99 kg N ha−1...

  17. Fertility Desire and Reproductive Health

    African Journals Online (AJOL)

    Understanding fertility desire and reproductive health care needs of HIV positive men and women in the era ... and related consequences. ... inform national policy decisions on PMTCT, HIV ... The study population was included proportional to.

  18. Food security: Fertilizing hidden hunger

    Science.gov (United States)

    Müller, Christoph; Elliott, Joshua; Levermann, Anders

    2014-07-01

    Atmospheric CO2 fertilization may go some way to compensating the negative impact of climatic changes on crop yields, but it comes at the expense of a deterioration of the current nutritional value of food.

  19. IVF-In Vitro Fertilization.

    Science.gov (United States)

    Kieffer, George H.

    1980-01-01

    Issues surrounding the controversial topic of in vitro fertilization and artificial manipulation of reproduction are discussed. The author examines the moral and ethical implications and presents results of a survey of various religious groups. (SA)

  20. Geographical and temporal variations in clozapine prescription for schizophrenia

    DEFF Research Database (Denmark)

    Nielsen, Jimmi; Røge, Rasmus; Schjerning, Ole

    2012-01-01

    Despite its unsurpassed efficacy in treatment-resistant schizophrenia, clozapine remains underutilized. Trends in the prescription of clozapine in patients with ICD-10 F20.x schizophrenia were assessed using data from Danish national registers. Three substudies were carried out: (i) an assessment...... of differences in national prescription patterns between 1996 and 2007 using a cross-sectional design; (ii) a comparison of time from first schizophrenia diagnosis to first prescription of clozapine in a five-year cohort study, using the Cox regression model, of two patient groups who were first diagnosed...

  1. Future Challenges and Opportunities in Online Prescription Drug Promotion Research

    Science.gov (United States)

    Southwell, Brian G.; Rupert, Douglas J.

    2016-01-01

    Despite increased availability of online promotional tools for prescription drug marketers, evidence on online prescription drug promotion is far from settled or conclusive. We highlight ways in which online prescription drug promotion is similar to conventional broadcast and print advertising and ways in which it differs. We also highlight five key areas for future research: branded drug website influence on consumer knowledge and behavior, interactive features on branded drug websites, mobile viewing of branded websites and mobile advertisements, online promotion and non-US audiences, and social media and medication decisions. PMID:26927597

  2. The study of prescriptive and descriptive models of decision making

    Directory of Open Access Journals (Sweden)

    Ashok A Divekar

    2012-04-01

    Full Text Available The field of decision making can be loosely divided into two parts: the study of prescriptive models and the study of descriptive models. Prescriptive decision scientists are concerned with prescribing methods for making optimal decisions. Descriptive decision researchers are concerned with the bounded way in which the decisions are actually made. The statistics courses treat risk from a prescriptive, by suggesting rational methods. This paper brings out the work done by many researchers by examining the psychological factors that explain how managers deviate from rationality in responding to uncertainty.

  3. 明胶接枝丙烯酸/丙烯酰胺缓释肥新型包膜材料的制备与应用%Preparation of Coated Material for Slow Release Fertilizer by Grafting Gelatin with Acrylic Acid/Acrylamide and Its Application

    Institute of Scientific and Technical Information of China (English)

    徐浩龙

    2012-01-01

    以过硫酸钾为引发剂,N,N-亚甲基双丙烯酰胺为交联剂,采用自由基聚合法使明胶与丙烯酸/丙烯酰胺进行接枝共聚,制备了一种明胶接枝丙烯酸/丙烯酰胺保水性缓释肥新型包膜材料,进行了吸水、保水、耐盐性检验并应用于包衣尿素的制备.结果表明:明胶用量为2.5%时,材料具有最大吸水率,在去离子水中达775g/g,在自来水中为395g/g.包衣尿素的氮素24h和28d释放率分别为12.11%、73.49%,缓释周期长达56d,达到“缓释肥国家标准”.%A water retention coated material for slow release fertilizer were prepared by graft copolymerization of gelatin with acrylic acid/acrylamide, during wliiuh the potassium persulfate was used as the initiator and the N,N' -methylenebisacrylamide was used as the cross-linking agent. Then, the water absorption, the water retention and the salt tolerance of the coated material were verified in order to apply in coated urea. When gelatin amount was 2.5%, the coated material had the best water absorption that was 775 g/g in deionized water and 395 g/g in tap water. The results showed that release rate of nitrogen from coated urea at 24 h and 28 d was 12.11% and 73.49, and the releasing period of coated urea reached 56 d, which meet the requirments of National Standards fur Slow Release Fertilizers.

  4. The Fertility Transition in Bavaria

    OpenAIRE

    Brown, John C.; Timothy W. Guinnane

    2001-01-01

    The decline of human fertility that occurred in Europe and North America in the nineteenth century, and elsewhere in the twentieth century, remains a topic of debate largely because there is no accepted explanation for the event. Disagreement persists in part because researchers have rarely used the detailed quantitative information necessary to form adequate tests of alternative theories. This paper uses district-level data from Bavaria to study the correlates of the decline of fertility in ...

  5. Children Procedures and Treatment (Fertility Issues)

    Science.gov (United States)

    ... approach the subject of fertility preservation with their cancer-stricken child? How is the Oncofertility Consortium addressing the fertility preservation needs of children? How do cancer and cancer treatment affect a child's fertility? Why should fertility preservation be a priority ...

  6. Viscosity prescription for gravitationally unstable accretion disks

    CERN Document Server

    Rafikov, Roman R

    2015-01-01

    Gravitationally unstable accretion disks emerge in a variety of astrophysical contexts - giant planet formation, FU Orioni outbursts, feeding of AGNs, and the origin of Pop III stars. When a gravitationally unstable disk is unable to cool rapidly it settles into a quasi-stationary, fluctuating gravitoturbulent state, in which its Toomre Q remains close to a constant value Q_0~1. Here we develop an analytical formalism describing the evolution of such a disk, which is based on the assumptions of Q=Q_0 and local thermal equilibrium. Our approach works in the presence of additional sources of angular momentum transport (e.g. MRI), as well as external irradiation. Thermal balance dictates a unique value of the gravitoturbulent stress \\alpha_{gt} driving disk evolution, which is a function of the local surface density and angular frequency. We compare this approach with other commonly used gravitoturbulent viscosity prescriptions, which specify the explicit dependence of stress \\alpha_{gt} on Toomre Q in an ad hoc...

  7. A new strategy for antidepressant prescription

    Directory of Open Access Journals (Sweden)

    Francis Lavergne

    2010-11-01

    Full Text Available From our research and literature search we propose an understanding of the mechanism of action of antidepressants (ADs that should lead to increase efficacy and tolerance.We understand that ADs promote synaptic plasticity and neurogenesis. This promotion is linked with dopamine (DA stimulation. Literature shows that all ADs (chemical, electroconvulsive therapy, repetitive transcranial magnetic stimulation, sleep deprivation increase at least one neuromodulator (serotonin, noradrenaline or DA; this article focuses on DA release or turn-over in the frontal cortex. DA increase promotes synaptic plasticity with an inverted U shape dose-response curve. Specific interaction between DA and glutamate relies on DA (D1 receptors and Glutamate (NMDA receptors and/or on neurotrophic factors activation. With the understanding that all ADs have a common, final, DArgic stimulation that promotes synaptic plasticity we can predict that:1AD efficiency is related to the compound strength for inducing DArgic stimulation.2AD efficiency presents a therapeutic window that coincides with the inverted U shape DA response curve.3AD delay of action is related to a synaptogenesis and neurogenesis delay of action.4The minimum efficient dose can be found by starting at a low dosage and increasing up to the patient response. 5An increased tolerance requires a concomitant prescription of a few ADs, with different or opposite adverse effects, at a very low dose.6ADs could improve all diseases with cognitive impairments and synaptic depression by increasing synaptic plasticity and neurogenesis.

  8. Improvement of natural pastures using liquid organic fertilizers

    Science.gov (United States)

    Ghambashidze, Giorgi; Gabedava, Giorgi; Abuladze, Paata

    2016-04-01

    Nowadays natural pastures remains the main source to supply livestock with fresh feed material in Georgia. Due to that common pasturelands are under continues grazing pressure and normally no measures are taken in order to improve pasture productivity and to protect soil from erosion. Unregulated stocking rate leads to overutilization of natural pastures causing reduction in productivity and soil fertility. It is especially evident in arid regions, where bare soil after removal of vegetation dries out and is subject to wind erosion. In many areas even with regulated stocking rate plant available soil nutrient pool is already diminished and vegetation cannot be recovered easily after grazing. Therefore it is essential to improve soil fertility, which provide adequate amount of nutrients to plants to regenerate. Ongoing study aims to compare effect of different types of organic fertilizers on natural pastures in combination with pasture rotation scheme in order to maintain soil fertility and prepare the basis for its gradual improvement. Initial results shows positive impact of liquid organic fertilizers which increased aboveground biomass production by 200-300 kg per hectare.

  9. The application of biosorption for production of micronutrient fertilizers based on waste biomass.

    Science.gov (United States)

    Tuhy, Lukasz; Samoraj, Mateusz; Michalak, Izabela; Chojnacka, Katarzyna

    2014-10-01

    In the present paper, new environmental-friendly fertilizer components were produced in biosorption process by the enrichment of the biomass with zinc, essential in plant cultivation. The obtained new preparations can be used as controlled release micronutrient fertilizers because microelements are bound to the functional groups present in the cell wall structures of the biomass. It is assumed that new fertilizing materials will be characterized by higher bioavailability, gradual release of micronutrients required by plants, and lower leaching to groundwater. The biological origin of the material used in plant fertilization results in the elimination of toxic effect towards plants and groundwater mainly caused by low biodegradability of fertilizers. Utilitarian properties of new formulations enable to reduce negative implications of fertilizers for environmental quality and influence ecological health. In this work, the utilitarian properties of materials such as peat, bark, seaweeds, seaweed post-extraction residues, and spent mushroom substrate enriched via biosorption with Zn(II) ions were examined in germination tests on Lepidium sativum. Obtained results were compared with conventional fertilizers-inorganic salt and chelate. It was shown that zinc fertilization led to biofortification of plant in these micronutrients. Moreover, the mass of plants fertilized with zinc was higher than in the control group.

  10. Reflections on fertility dynamics in Romania.

    Science.gov (United States)

    Bratu, Eugenia Claudia; Minca, Dana Galieta

    2012-01-01

    Aims to highlight the changes occurred in the evolution of the fertility phenomenon in Romania, focusing on developments in the general fertility rate, total fertility rate, number of live births, and on the construction of specific indicators to reveal the source of demographic change. Several theories on the factors that may cause fertility decline it were outlined, underlining the presence of these factors during fertility dynamics in our country. After 1990, population decline may be explained by a close inter-relationship between economic theories (worsening economic conditions lead to decreased fertility) and the second demographic transition (postponement of births, fertility change model).

  11. Expanded pharmacy technician roles: Accepting verbal prescriptions and communicating prescription transfers.

    Science.gov (United States)

    Frost, Timothy P; Adams, Alex J

    2016-11-29

    As the role of the clinical pharmacist continues to develop and advance, it is critical to ensure pharmacists can operate in a practice environment and workflow that supports the full deployment of their clinical skills. When pharmacy technician roles are optimized, patient safety can be enhanced and pharmacists may dedicate more time to advanced clinical services. Currently, 17 states allow technicians to accept verbal prescriptions called in by a prescriber or prescriber's agent, or transfer a prescription order from one pharmacy to another. States that allow these activities generally put few legal limitations on them, and instead defer to the professional judgment of the supervising pharmacist whether to delegate these tasks or not. These activities were more likely to be seen in states that require technicians to be registered and certified, and in states that have accountability mechanisms (e.g., discipline authority) in place for technicians. There is little evidence to suggest these tasks cannot be performed safely and accurately by appropriately trained technicians, and the track record of success with these tasks spans four decades in some states. Pharmacists can adopt strong practice policies and procedures to mitigate the risk of harm from verbal orders, such as instituting read-back/spell-back techniques, or requiring the indication for each phoned-in medication, among other strategies. Pharmacists may also exercise discretion in deciding to whom to delegate these tasks. As the legal environment becomes more permissive, we foresee investment in more robust education and training of technicians to cover these activities. Thus, with the adoption of robust practice policies and procedures, delegation of verbal orders and prescription transfers can be safe and effective, remove undue stress on pharmacists, and potentially free up pharmacist time for higher-order clinical care. Copyright © 2016 Elsevier Inc. All rights reserved.

  12. [[Trends in marriage and fertility in Japan: major findings from the Tenth Japanese National Fertility Survey

    Science.gov (United States)

    Atoh, M; Takahashi, S; Nakano, E; Watanabe, Y; Kojima, H; Kaneko, R

    1993-10-01

    The authors review trends in marriage and fertility in Japan, using data from the 1993 Japanese National Fertility Survey. Information is included on age at marriage, arranged and voluntary marriages, length of time from initial meeting to marriage, changes in age at marriage, fertility, socioeconomic differentials in fertility, and fertility preferences. (SUMMARY IN ENG)

  13. Soils, Crops and Fertilizer Use. A What, How and Why Guide. Appropriate Technologies for Development. Reprint R-8.

    Science.gov (United States)

    Leonard, David

    This manual, prepared for use by Peace Corps volunteers in developing countries, has been designed as an on-the-job reference for soil management and fertilizer use at the small farmer level. It provides information on yield-boosting techniques, especially in the areas of soil conservation, organic and chemical fertilizer use, and the safe and…

  14. How Typewriters Changed Correspondence: An Analysis of Prescription and Practice.

    Science.gov (United States)

    Walker, Sue

    1984-01-01

    Notes changes in the visual organization of correspondence brought about by the typewriter. Discusses the development of these changes, drawing examples both from the prescriptions for and the practice of commercial correspondence. (FL)

  15. The Language of Civil Engineering: Descriptive, Prescriptive, and Persuasive.

    Science.gov (United States)

    Machauf, Liora

    1990-01-01

    Focuses on the language of civil engineering as manifested in the professional journal "Civil Engineering ASCE." Articles are analyzed, both syntactically and lexically, in terms of three major rhetorical functions: description, prescription, and persuasion. (17 references) (GLR)

  16. Buying Prescription Medicine Online: A Consumer Safety Guide

    Science.gov (United States)

    ... Seniors Tips for Parents En Español Prescription Drug Advertising Information for Healthcare Professionals (Drugs) FDA Drug Info ... feeds Follow FDA on Twitter Follow FDA on Facebook View FDA videos on YouTube View FDA photos ...

  17. Investigation of Medication Errors: A Prescription Survey from Sri ...

    African Journals Online (AJOL)

    Conclusion: Prescription errors are common in outpatient settings of Aluthgama and Kandy areas in. Sri Lanka. ..... irrational drug use in India were similar to the results that were .... and nature of dosing errors in paediatric medications:.

  18. 75 FR 16235 - Electronic Prescriptions for Controlled Substances

    Science.gov (United States)

    2010-03-31

    ...; these include opioids, stimulants, depressants, hallucinogens, anabolic steroids, and drugs that are... consequences of prescription drug abuse are seen in the data collected by the Substance Abuse and Mental...

  19. The “Black Box” of Prescription Drug Diversion

    Science.gov (United States)

    Inciardi, James A.; Surratt, Hilary L.; Cicero, Theodore J.; Kurtz, Steven P.; Martin, Steven S.; Parrino, Mark W.

    2009-01-01

    A variety of surveys and studies are examined in an effort to better understand the scope of prescription drug diversion and to determine if there are consistent patterns of diversion among various populations of prescription drug abusers. Data are drawn from the RADARS® System, the National Survey of Drug Use and Health (NSDUH), the Delaware School Survey, and a series of quantitative and qualitative studies conducted in Miami, Florida. The data suggest that the major sources of diversion include drug dealers, friends and relatives, smugglers, pain patients, and the elderly, but these vary by the population being targeted. In all of the studies examined, the use of the Internet as a source for prescription drugs is insignificant. Little is known about where drug dealers are obtaining their supplies, and as such, prescription drug diversion is a “black box” requiring concentrated systematic study. PMID:20155603

  20. Prescription and Cost Consideration at a Diabetic Clinic in Ibadan ...

    African Journals Online (AJOL)

    opsig

    Prescription and Cost Consideration at a Diabetic Clinic in Ibadan,. Nigeria: A Report ... drugs with proven efficacy based on best evidence, the prevailing social ... pharmacy using the current hospital drug-pricing list calculated the cost of the ...

  1. Which Classes of Prescription Drugs Are Commonly Misused?

    Science.gov (United States)

    ... may include restlessness, muscle and bone pain, insomnia, diarrhea, vomiting, cold flashes with goose bumps, and involuntary leg movements. 29 Misuse of prescription opioids is also a risk factor for transitioning to heroin use. Read more about ...

  2. Opioid prescriptions before and after high-energy trauma

    DEFF Research Database (Denmark)

    Zwisler, Stine T; Hallas, Jesper; Larsen, Morten S

    2015-01-01

    OBJECTIVE: To describe the legal use of opioids in adult patients before and after high-energy trauma. DESIGN: The study was a retrospective database study. SETTING: Clinical care outside hospitals. PATIENTS: All patients who suffered high-energy trauma and were brought to Odense University...... Hospital (OUH), Denmark, in 2007 and 2008 were retrieved from the trauma database. These patients were linked with data on opioid use from the regional prescription database. In all, 938 patients were included. MAIN OUTCOME MEASURE: Redemption of opioid prescription during the 6 months prior...... to a multitrauma or redemption of two or more prescriptions for opioids 6 months or later after a multitrauma. RESULTS: Of the 938 patients brought to OUH with severe trauma within the study period, 61 patients died (7 percent) and six of these had redeemed prescriptions for opioids within 6 months prior...

  3. Toward Validation of the Diagnostic-Prescriptive Model

    Science.gov (United States)

    Ysseldyke, James E.; Sabatino, David A.

    1973-01-01

    Criticized are recent research efforts to validate the diagnostic prescriptive model of remediating learning disabilities, and proposed is a 6-step psychoeducational model designed to ascertain links between behavioral differences and instructional outcomes. (DB)

  4. Prescription patterns and utilisation of antihypertensive drugs in a ...

    African Journals Online (AJOL)

    Prescription patterns and utilisation of antihypertensive drugs in a specialist ... use in the management of essential hypertension in a specialist hospital and its ... of encounters, there were a total of 1544 drugs and 28 non-drug interventions.

  5. Pattern of Prescription of Antibiotics among Dental Practitioners in ...

    African Journals Online (AJOL)

    consistency in the antibiotic prescription pattern among dentists in Jeddah and overall low adherence to the ..... manuscript editing and review. Appendix I: Clinical case ... adhesion deficiency, antibiotic therapy is indicated. a*Adapted from ...

  6. Immersible ergocycle prescription as a function of relative exercise intensity

    Directory of Open Access Journals (Sweden)

    Mauricio Garzon

    2017-06-01

    Conclusion: The %HRR–%VO2R relationship appears to be the most accurate for exercise training prescription on IE. This study offers new tools to better prescribe, control, and individualize exercise intensity on IE.

  7. Forest Management Prescription : Compartment 9 : Mingo National Wildlife Refuge

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This is the Forest Management Prescription for Compartment 9 of Mingo NWR. It provides a description of the compartment, management objectives, proposed management...

  8. prescriptions involving analgesic drugs at a secondary health facility ...

    African Journals Online (AJOL)

    per patient were recorded and prescriptions involving analgesics were further ... documentation of any untoward effects in the over ... files were sent to the Pharmacy Department of the ..... Efficacy and safety of metamizol vs. acetylsalicylic acid.

  9. Basic Stand Alone Medicare Prescription Drug Events PUF

    Data.gov (United States)

    U.S. Department of Health & Human Services — This is a Public Use File for Prescription Drug Events drawn from the 2008 Beneficiary Summary File of Medicare beneficiaries enrolled during the calendar year 2008,...

  10. Opioid prescriptions before and after high-energy trauma

    DEFF Research Database (Denmark)

    Zwisler, Stine T; Hallas, Jesper; Larsen, Morten S

    2015-01-01

    OBJECTIVE: To describe the legal use of opioids in adult patients before and after high-energy trauma. DESIGN: The study was a retrospective database study. SETTING: Clinical care outside hospitals. PATIENTS: All patients who suffered high-energy trauma and were brought to Odense University...... Hospital (OUH), Denmark, in 2007 and 2008 were retrieved from the trauma database. These patients were linked with data on opioid use from the regional prescription database. In all, 938 patients were included. MAIN OUTCOME MEASURE: Redemption of opioid prescription during the 6 months prior...... to a multitrauma or redemption of two or more prescriptions for opioids 6 months or later after a multitrauma. RESULTS: Of the 938 patients brought to OUH with severe trauma within the study period, 61 patients died (7 percent) and six of these had redeemed prescriptions for opioids within 6 months prior...

  11. FERTILIZERS SALES AND SERVICE. AGRICULTURAL SUPPLY - SALES AND SERVICE OCCUPATIONS, MODULE NUMBER 9.

    Science.gov (United States)

    Ohio State Univ., Columbus. Center for Vocational and Technical Education.

    THE PURPOSE OF THIS GUIDE IS TO ASSIST TEACHERS IN PREPARING HIGH SCHOOL AND POST-HIGH SCHOOL STUDENTS FOR AGRICULTURAL SUPPLY OCCUPATIONS. ONE OF A SERIES, THIS MODULE WAS DEVELOPED ON THE BASIS OF STATE STUDIES BY A NATIONAL TASK FORCE. THE SPECIFIC OBJECTIVE IS TO PREPARE STUDENTS FOR ENTRY AND ADVANCEMENT IN FERTILIZER SALES AND SERVICE.…

  12. An Exercise Prescription Intervention Program with Periodic Ergometric Grading

    Science.gov (United States)

    Owen, C. A.; Beard, E. F.

    1970-01-01

    A long term exercise prescription type of physical conditioning program has been available to executive personnel of the NASA Manned Spacecraft Center for the past two years. Periodic ergometric testing with a heart rate controlled, automatically programmed, bicycle ergometer is used to follow the individual's progress and appropriately alter his exercise prescription from time to time. Such a program appears feasible, and acceptance is excellent, dropout rates small and periodic testing participation good. Subjects training diligently can maintain satisfactory levels of conditioning.

  13. Transferring Lens Prescriptions Between Lens-Design Programs

    Science.gov (United States)

    Stacy, John E.; Wooley, Laura; Carlin, Brian

    1989-01-01

    Optical Lens Prescription Data Formatter computer program enables user to transfer complicated lens prescriptions quickly and easily from one major optical-design program to another and back again. One can take advantage of inherent strength of either program. Programs are ACCOS V from Scientific Calculations, Inc., of Fishers, NY, and CODE V from Optical Research Associates of Pasadena, CA. VAX version written in FORTRAN.

  14. Rationality of Antimicrobial Prescriptions in Community Pharmacy Users.

    Directory of Open Access Journals (Sweden)

    Sara I V C Lima

    Full Text Available Although there is a conflict between the treatment benefits for a single individual and society, restrictions on antibiotic use are needed to reduce the prevalence of resistance to these drugs, which is the main result of irrational use. Brazil, cataloged as a pharmemerging market, has implemented restrictive measures for the consumption of antibiotics. The objective of this study was to investigate the quality of antimicrobial prescriptions and user knowledge of their treatment with these drugs.A two-stage cross-sectional, combined and stratified survey of pharmacy users holding an antimicrobial prescription was conducted in the community between May and November 2014. A pharmacist analyzed each prescription for legibility and completeness, and applied a structured questionnaire to the users or their caregivers on their knowledge regarding treatment and user sociodemographic data. An estimated 29.3% of prescriptions had one or more illegible items, 91.3% had one or more missing items, and 29.0% had both illegible and missing items. Dosing schedule and patient identification were the most commonly unreadable items in prescriptions, 18.81% and 12.14%, respectively. The lack of complete patient identification occurred in 90.53% of the prescriptions. It is estimated that 40.3% of users have used antimicrobials without prescription and that 46.49% did not receive any guidance on the administration of the drug.Despite the measures taken by health authorities to restrict the misuse of antimicrobials, it was observed that prescribers still do not follow the criteria of current legislation, particularly relating to items needed for completion of the prescription. Moreover, users receive little information about their antimicrobial treatment.

  15. Patriarchy and fertility in Albania

    Directory of Open Access Journals (Sweden)

    Mathias Lerch

    2013-07-01

    Full Text Available BACKGROUND Theories of fertility collapse in the post-socialist era imply a decline in the moral primacy of traditional social institutions. Yet gender inequality actually increased in many countries, and there is a scarcity of empirical evidence for the role played by traditional social institutions in reproductive decision-making. OBJECTIVE We investigate whether patriarchal institutions sustained the fertility levels in Albania. The geography of marriage and family enlargement is related to the importance of patriarchy in kinship organisation and in the public sphere. To account for this spatial relationship we test the evidence for different pathways in patriarchal influence on reproductive decision-making including social effects, socialisation in patriarchal ideals, and the promotion of male fertility. METHODS We reconstruct reproductive histories from the 2001 Census and use data on attitudes and fertility intentions from the Reproductive and Health Survey 2002. Multilevel logistic regressions on marriage and (the intention of higher order births are used. RESULTS A majority of women endorsed patriarchal ideals and fertility transition was less advanced in more patriarchal municipalities. Patriarchal kinship organisation promoted early marriages and high fertility, which is shown to be achieved by social learning among peers and intergenerational social influences respectively, as well as by women's socialisation and a stopping behaviour in childbearing dominated by son-preference. Although gender inequality in the public sphere has also sustained the level of fertility and decreased the risk of marriage, it was not accounted for by these pathways of patriarchal influence. CONCLUSIONS Despite Albania's gradual opening to the world in a period of economic and political crisis, traditional social institutions remain important for family behaviours.

  16. SOIL FERTILITY EVALUATION FOR FERTILISER RECOMMENDATION USING HYPERION DATA

    Directory of Open Access Journals (Sweden)

    Ranendu Ghosh

    2015-12-01

    Full Text Available Soil fertility characterised by nitrogen, phosphorus, potassium, calcium, magnesium and sulphur is traditionally measured from soil samples collected from the field. The process is very cumbersome and time intensive. Hyperspectral data available from Hyperion payload of EO 1 was used for facilitating preparation of soil fertility map of Udaipur district of Rajasthan state, India. Hyperion data was pre-processed for band and area sub setting, atmospheric correction and reflectance data preparation. Spectral analysis in the form of SFF and PPI were carried out for selecting the ground truth sites for soil sample collection. Soil samples collected from forty one sites were analysed for analysis of nutrient composition. Generation of correlogram followed by multiple regressions was done for identifying the most important bands and spectral parameters that can be used for nutrient map generation.

  17. Soil Fertility Evaluation for Fertiliser Recommendation Using Hyperion Data

    Science.gov (United States)

    Ghosh, Ranendu; Padmanabhan, N.; Patel, K. C.

    2015-12-01

    Soil fertility characterised by nitrogen, phosphorus, potassium, calcium, magnesium and sulphur is traditionally measured from soil samples collected from the field. The process is very cumbersome and time intensive. Hyperspectral data available from Hyperion payload of EO 1 was used for facilitating preparation of soil fertility map of Udaipur district of Rajasthan state, India. Hyperion data was pre-processed for band and area sub setting, atmospheric correction and reflectance data preparation. Spectral analysis in the form of SFF and PPI were carried out for selecting the ground truth sites for soil sample collection. Soil samples collected from forty one sites were analysed for analysis of nutrient composition. Generation of correlogram followed by multiple regressions was done for identifying the most important bands and spectral parameters that can be used for nutrient map generation.

  18. Self-prescription practices in recent Latino immigrants.

    Science.gov (United States)

    Coffman, Maren J; Shobe, Marcia A; O'Connell, Beth

    2008-01-01

    Self-prescription involves the purchase and use of restricted medications without medical advice. Although common in Central and South American countries, little is known about this practice among Latino immigrants in the United States. The purpose of this study, therefore, was to explore how Latino immigrants obtain and use prescription medications without accessing the formal health care system. This exploratory descriptive study used focus groups to gain an understanding of the use of prescription medications without medical care. Three focus group discussions were held with 19 adult Latino immigrants who were new residents in the United States, and did not have health insurance; most were undocumented. Analysis of the data revealed 4 major themes: (a) health care barriers, (b) cultural norms, (c) self-care, and (d) self-prescription. The data indicate that this population experiences significant barriers to accessing health care, forcing them to seek treatment alternatives including the purchase and use of drugs manufactured in Mexico. There are many public health and safety concerns related to self-prescription practices. Nurses need to be aware of the barriers to health care that lead to these potentially dangerous medication practices, and to recognize and understand self-prescription.

  19. Predicting prosthetic prescription after major lower-limb amputation

    Directory of Open Access Journals (Sweden)

    Linda Resnik, PT, PhD, OCS

    2015-09-01

    Full Text Available We describe prosthetic limb prescription in the first year following lower-limb amputation and examine the relationship between amputation level, geographic region, and prosthetic prescription. We analyzed 2005 to 2010 Department of Veterans Affairs (VA Inpatient and Medical Encounters SAS data sets, Vital Status death data, and National Prosthetic Patient Database data for 9,994 Veterans who underwent lower-limb amputation at a VA hospital. Descriptive statistics and bivariates were examined. Cox proportional hazard models identified factors associated with prosthetic prescription. Analyses showed that amputation level was associated with prosthetic prescription. The hazard ratios (HRs were 1.41 for ankle amputation and 0.46 for transfemoral amputation compared with transtibial amputation. HRs for geographic region were Northeast = 1.49, Upper Midwest = 1.26, and West = 1.39 compared with the South (p < 0.001. African American race, longer length of hospital stay, older age, congestive heart failure, paralysis, other neurological disease, renal failure, and admission from a nursing facility were negatively associated with prosthetic prescription. Being married was positively associated. After adjusting for patient characteristics, people with ankle amputation were most likely to be prescribed a prosthesis and people with transfemoral amputation were least likely. Geographic variation in prosthetic prescription exists in the VA and further research is needed to explain why.

  20. Illicit Use of Prescription Opiates among Graduate Students.

    Science.gov (United States)

    Varga, Matthew D; Parrish, Mark

    2015-01-01

    Through this study the authors assessed the prevalence rate, reasons for use, and poly-substance use of prescription opiates among graduate students. The authors employed a cross-sectional survey research design using an online, self-administered questionnaire to assess the prevalence rates of prescription opiate use among graduate students (N = 1,033), reasons for use, and their likelihood for poly-substance use. The survey was e-mailed to 5,000 graduate students. Graduate students (19.7%) reported illicit use of prescription opiates in their lifetime and 6.6% reported past-year illicit use. Those who indicated illicitly using prescription opiates did so for self-medication reasons; a few respondents indicated recreational use. Students using prescription opiates were 75% less likely to use marijuana; 79% less likely to use cocaine; and 75% less likely to use ecstasy. Graduate students are illicitly using prescription opiates, but primarily for self-medication, and, while doing so, are less likely to use other substances.

  1. Description, prescription and the choice of discount rates

    Energy Technology Data Exchange (ETDEWEB)

    Baum, Seth D. [Rock Ethics Institute, Pennsylvania State University, 201 Willard Building, University Park, PA 16802 (United States); Department of Geography, Pennsylvania State University, 302 Walker Building, University Park, PA 16802 (United States)

    2009-11-15

    The choice of discount rates is a key issue in the analysis of long-term societal issues, in particular environmental issues such as climate change. Approaches to choosing discount rates are generally placed into two categories: the descriptive approach and the prescriptive approach. The descriptive approach is often justified on grounds that it uses a description of how society discounts instead of having analysts impose their own discounting views on society. This paper analyzes the common forms of the descriptive and prescriptive approaches and finds that, in contrast with customary thinking, both forms are equally descriptive and prescriptive. The prescriptions concern who has standing (i.e. who is included) in society, how the views of these individuals are measured, and how the measurements are aggregated. Such prescriptions are necessary to choose from among the many possible descriptions of how society discounts. The descriptions are the measurements made given a choice of measurement technique. Thus, the labels 'descriptive approach' and 'prescriptive approach' are deeply misleading, as analysts cannot avoid imposing their own views on society. (author)

  2. Doctor Shopping Behavior and the Diversion of Prescription Opioids.

    Science.gov (United States)

    Simeone, Ronald

    2017-01-01

    "Doctor shopping" as a means of prescription opioid diversion is examined. The number and percentage of prescriptions and morphine-equivalent milligrams diverted in this manner are estimated by state and molecule for the period 2008-2012. Eleven billion prescriptions with unique patient, doctor, and pharmacy identifiers were used to construct diversion "events" that involved between 1 and 6 unique doctors and between 1 and 6 unique pharmacies. Diversion thresholds were established based on the probability of each contingency. A geographically widespread decline occurred between 2008 and 2012. The number of prescriptions diverted fell from approximately 4.30 million (1.75% of all prescriptions) in 2008 to approximately 3.37 million (1.27% of all prescriptions) in 2012, and the number of morphine-equivalent milligrams fell from approximately 6.55 metric tons (2.95% of total metric tons) in 2008 to approximately 4.87 metric tons (2.19% of total metric tons) in 2012. Diversion control efforts have likely been effective. But given increases in opioid-related deaths, opioid-related drug treatment admissions, and the more specific resurgence of heroin-related events, it is clear that additional public health measures are required.

  3. The economics of fertility.

    Science.gov (United States)

    Loraine, J A

    1982-01-01

    The statement that economics and fertility are closely interrelated is a truism. The classical economists--Adam Smith, Thomas Malthus, Karl Marx, John Stuart Mill and John Maynard Keynes appreciated this fact, and their reviews are recounted and their prescience is assessed. Adam Smith (1723-1790) was primarily concerned with the desire of humankind to better his/her material conditions. Although he did not put forward a specific population policy, the tenet of his writing is pronatalist. Economic advantages would accrue to parents by the production of many children. Yet, underneath Smith's optimism, there was an apocalyptic vision of the distant future, i.e., the "steady state" when resources would be depleted or near exhaustion, when capital accumulation would have ceased, and living standards would be dropping vertiginously. In his 1st "Essay on Population" Malthus maintained that "the power of population is infinitely greater than the power of the earth to produce subsistence of men." Malthus can be complimented on his prescience. There is little question that the planet of today is grossly overpopulated and that a great gulf exists between numbers of people and their aspirations and the resources which the earth can provide for them. Malthus was particularly concerned about the population food dilemma, and that is still much in evidence in 1982. 2 concomitants of overpopulation--excessive urbanization and joblessness--could not be foreseen by Malthus. Marx did not deny the basic tenet promulgated by Malthus but to him this was simply an artifact of capitalist society which required "enormous reserves of proletarians" in order to maintain its odius system. Officially Communist governments remain in a Marxist straitjacket regarding the population issue. Mills approach was strongly antinatalist; he saw little need for an increase in human numbers. Mills was concerned that because of unlimited population growth and wealth the earth would lose much of its

  4. Diet and fertility in cattle

    Directory of Open Access Journals (Sweden)

    Petrujkić Tihomir

    2003-01-01

    Full Text Available The diet of high-yield dairy cows process a very complex and acute problem. Much new knowledge in the area of production and preparation of feedstuffs, diet technology, and the interactions that occur between the components of the nutritive feed ration are required in order to resolve this problem. It is necessary constantly to coordinate feed norms with genetic potential which is ever changing and advanced. The observed problems must be resolved using multidisciplinary methods so that a diet can yield good health, and that health contribute to better reproduction and possibilities for more successful breeding and improved performance in cattle farming. In certain countries, thanks to their geographic position and climatic conditions which allow rainfall throughout the year, a natural green diet can be applied, which provides large numbers of green mass components, and with additives which can be supplemented relatively easily. This type of diet is not possible in our farms. It is very important to know which feedstuff components are laking for certain categories of cattle. The used ration must be constant and administered to animals of certain age or production characteristics in order to improve production results at cattle farms. A great problem occurs when diet is reduced due to dried grass and the resulting stress in animals. A 50% diet reduction in young cattle often results in the occurrence of respiratory diseases. Following 10-14 days of treatment, the disease disappears in young animals, but the energy deficit leads to the weakening (depression of the immune system. Even a so-called high-energy diet often causes respiratory diseases. A diet deficient in proteins also affects cows after lactation, as opposed to a normative diet, and a reduced protein diet disturbs the microbial activity in the rumen and the synthesis of compounds which are important for both the cow and the calf, making room for the incidence of metabolic diseases, most

  5. In situ polymerization coating and characteristics of coated NPK compound fertilizer

    Institute of Scientific and Technical Information of China (English)

    WANG Zhenghui; ZHU Homing

    2007-01-01

    Controlled release NPK compound fertilizers were prepared by means of in situ polymerization of monomers on the surface of fertilizer granules at room temperature. Methacrylate, α-methyl acrylic acid, and ethylene dimethylacrylate were used as monomers, Dibenzoyl peroxide as initiator, and cobalt naphthenate, and triethyl amine as promoters. The structures of coating materials were characterized by IR spectra. The thermogravimetric analysis result indicated that the coating materials were of good thermal stability. The mean thickness of single coating measured with screw gauge was ca. 140 μm. The morphologies of uncoated and coated fertilizer granules analyzed by using scanning electron microscopy were changed from porosities and gullies to hills and plain. The release rate of coated compound fertilizers in water could be controlled by the hydrophicity and thickness of coating. The increase in coating hydrophicity caused the increase in release rate of fertilizer. The increase in thickness of coating slowed the release rate.

  6. [Development and evaluation of fertilizers cemented and coated with organic-inorganic materials].

    Science.gov (United States)

    Xiao, Qiang; Wang, Jia-Chen; Zuo, Qiang; Zhang, Lin; Liu, Bao-Cun; Zhao, Tong-Ke; Zou, Guo-Yuan; Xu, Qiu-Ming

    2010-01-01

    Four kinds of organic-inorganic cementing and coating materials were prepared by a coating method using water as the solvent, and the corresponding cemented and coated fertilizers (B2, PS, F2, and F2F) were produced by disc pelletizer. The tests on the properties of these fertilizers showed that the granulation rate, compression strength, and film-forming rate were B2 > PS > F2 > F2F. Soil column leaching experiment showed that the curve of accumulated nitrogen-dissolving rate was the gentlest for B2. In 48 days, the accumulated nitrogen-dissolving rate was in the order of B2, 54.65% fertilizers had better effects on corn yield, among which, B2 was the best, with the corn yield and fertilizer use efficiency increased by 19.72% and 20.30%, respectively. The yield-increasing effect of other test fertilizers was in the order of PS > F2 > F2F.

  7. Bodily differences between Cold- and Heat-prescription groups in Sasang medicine

    Directory of Open Access Journals (Sweden)

    Young Joo Park

    2016-06-01

    Conclusion: In the SY-type men, the chest circumference was significantly greater in the Heat-prescription group compared to the Cold-prescription group. In the TE-type men, the rib-to-pelvic circumference ratio was significantly higher in the Heat-prescription group than in the Cold-prescription group.

  8. Primogeniture and fertility: fertility models with unequal bequest.

    Science.gov (United States)

    Parsons, D O

    1984-01-01

    Models of the family which incorporate bequest inequality into the fertility decision were developed. Following a discussion on this topic by H.J. Habakkuk, discussion focuses on preindustrial and early industrial England and Western Europe. An attempt was made to develop fertility models which do not assume that all children are treated equally but instead recognize the special role that the eldest child often plays in the family. The fertility consequences of primogeniture are explored in 2 different fertility models. In the initial behavioral model due to Habakkuk, fertility is a function of marriage age and marriage age is a function of time required for one's capital to reach some social minimum required for household formation. In such a model it is possible to show that an increasingly unequal bequest between children will reduce aggregate fertility in the following generation. The introduction of explicit fertility choice considerably complicates the model. The effect of greater relative bequests to the eldest child, if motivated by parental preference, depends on the role children other than the eldest play in the family. If parents would normally choose to have more children the larger the total bequest they intend to bestow on all their children, the effect of primogeniture will be to reduce fertility. The wealth parents allocate to the eldest with primogeniture has an impact on the other children equivalent to a general decline in family bequests. Similar conclusions hold if the shift of wealth to the eldest is the result of a legal constraint that a specified share of the estate be allocated to the eldest. Yet, if the constraint is posed as a required proportionality between the wealth of the eldest and the average wealth of other children, the effect of primogeniture laws (or conversely equality laws) is ambiguous. The same negative wealth effect exists for the younger children as wealth is diverted to the eldest. A positive fertility effect also

  9. Encapsulated Urea-Kaolinite Nanocomposite for Controlled Release Fertilizer Formulations

    OpenAIRE

    Siafu Ibahati Sempeho; Hee Taik Kim; Egid Mubofu; Alexander Pogrebnoi; Godlisten Shao; Askwar Hilonga

    2015-01-01

    Urea controlled release fertilizer (CRF) was prepared via kaolinite intercalation followed by gum arabic encapsulation in an attempt to reduce its severe losses associated with dissolution, hydrolysis, and diffusion. Following the beneficiation, the nonkaolinite fraction decreased from 39.58% to 0.36% whereas the kaolinite fraction increased from 60.42% to 99.64%. The X-ray diffractions showed that kaolinite was a major phase with FCC Bravais crystal lattice with particle sizes ranging betwee...

  10. Encapsulated Urea-Kaolinite Nanocomposite for Controlled Release Fertilizer Formulations

    OpenAIRE

    Siafu Ibahati Sempeho; Hee Taik Kim; Egid Mubofu; Alexander Pogrebnoi; Godlisten Shao; Askwar Hilonga

    2015-01-01

    Urea controlled release fertilizer (CRF) was prepared via kaolinite intercalation followed by gum arabic encapsulation in an attempt to reduce its severe losses associated with dissolution, hydrolysis, and diffusion. Following the beneficiation, the nonkaolinite fraction decreased from 39.58% to 0.36% whereas the kaolinite fraction increased from 60.42% to 99.64%. The X-ray diffractions showed that kaolinite was a major phase with FCC Bravais crystal lattice with particle sizes ranging betwee...

  11. Preparation of Coating Material for Slow Release Fertilizer by Amylum/Polyacrylic Acid/Collophanite and Its Properties%淀粉/聚丙烯酸/胶磷矿缓释肥包膜材料的制备及性能研究

    Institute of Scientific and Technical Information of China (English)

    徐浩龙

    2012-01-01

    The N,N'-Methylenebisacrylamide was used as crosslinking agent and the potassium persulfate was used as initiator to copolymerization and cross -linking of collophanite, amylum and acrylate by using aqueous solution polymerization method to prepare a kind of coating material with water retention and phosphor containing for coating slow release urea fertilizer. When mass fraction of phosphorite was 14%, the water absorption amount of the coating material was 560 g/g for deionized water and 254 g/g for tap water, while the slow release period of coated urea was 65 d. Therefore, the coating material meets the technological standards of GB/T23348-2009.%采用水溶液聚合法,以N,N’-亚甲基双丙烯酰胺为交联剂,过硫酸钾为引发剂,使胶磷矿、淀粉与丙烯酸盐共聚交联,制备了一种兼具保水性的含磷缓释肥包膜材料并应用于包衣尿素缓释肥.磷矿质量分数为14%时,材料在去离子水、自来水中的吸水率分别为560 g/g、254 g/g,包衣尿素的缓释周期为65 d,符合GB/T23348-2009规定的缓释要求.

  12. Quality of Online Pharmacies and Websites Selling Prescription Drugs: A Systematic Review

    Science.gov (United States)

    Merla, Anna; Schulz, Peter J; Gelatti, Umberto

    2011-01-01

    Background Online pharmacies are companies that sell pharmaceutical preparations, including prescription-only drugs, on the Internet. Very little is known about this phenomenon because many online pharmacies operate from remote countries, where legal bases and business practices are largely inaccessible to international research. Objective The aim of the study was to perform an up-to-date and comprehensive review of the scientific literature focusing on the broader picture of online pharmacies by scanning several scientific and institutional databases, with no publication time limits. Methods We searched 4 electronic databases up to January 2011 and the gray literature on the Internet using the Google search engine and its tool Google Scholar. We also investigated the official websites of institutional agencies (World Health Organization, and US and European centers for disease control and drug regulation authorities). We focused specifically on online pharmacies offering prescription-only drugs. We decided to analyze and report only articles with original data, in order to review all the available data regarding online pharmacies and their usage. Results We selected 193 relevant articles: 76 articles with original data, and 117 articles without original data (editorials, regulation articles, or the like) including 5 reviews. The articles with original data cover samples of online pharmacies in 47 cases, online drug purchases in 13, consumer characteristics in 15, and case reports on adverse effects of online drugs in 12. The studies show that random samples with no specific limits to prescription requirements found that at least some websites sold drugs without a prescription and that an online questionnaire was a frequent tool to replace prescription. Data about geographical characteristics show that this information can be concealed in many websites. The analysis of drug offer showed that online a consumer can get virtually everything. Regarding quality of drugs

  13. Quality of online pharmacies and websites selling prescription drugs: a systematic review.

    Science.gov (United States)

    Orizio, Grazia; Merla, Anna; Schulz, Peter J; Gelatti, Umberto

    2011-09-30

    Online pharmacies are companies that sell pharmaceutical preparations, including prescription-only drugs, on the Internet. Very little is known about this phenomenon because many online pharmacies operate from remote countries, where legal bases and business practices are largely inaccessible to international research. The aim of the study was to perform an up-to-date and comprehensive review of the scientific literature focusing on the broader picture of online pharmacies by scanning several scientific and institutional databases, with no publication time limits. We searched 4 electronic databases up to January 2011 and the gray literature on the Internet using the Google search engine and its tool Google Scholar. We also investigated the official websites of institutional agencies (World Health Organization, and US and European centers for disease control and drug regulation authorities). We focused specifically on online pharmacies offering prescription-only drugs. We decided to analyze and report only articles with original data, in order to review all the available data regarding online pharmacies and their usage. We selected 193 relevant articles: 76 articles with original data, and 117 articles without original data (editorials, regulation articles, or the like) including 5 reviews. The articles with original data cover samples of online pharmacies in 47 cases, online drug purchases in 13, consumer characteristics in 15, and case reports on adverse effects of online drugs in 12. The studies show that random samples with no specific limits to prescription requirements found that at least some websites sold drugs without a prescription and that an online questionnaire was a frequent tool to replace prescription. Data about geographical characteristics show that this information can be concealed in many websites. The analysis of drug offer showed that online a consumer can get virtually everything. Regarding quality of drugs, researchers very often found

  14. Fabrication and evaluation of variable rate fertilizer system

    Directory of Open Access Journals (Sweden)

    A Damirchi

    2015-09-01

    Full Text Available Introduction: In conventional farming, the soil and crop are considered uniform in different locations of the farm and the fertilizers are applied according to the average of soil needs with an additional percentage for safety (Loghavi, 2003. Non-essential chemical fertilizers in the field have harmful effects and social, economic and environmental concerns will increase. Many fertilizers go into the surface waters and ground waters and cause poisoning and environmental pollution without being absorbed by the plants. In variable rate technology, the soil fertilizer needs a map of all parts of the farm which is prepared with the GIS system. This map is uploaded on the computer before variable rate fertilizer machine starts. The computer continually controls the fertilizing rate for each part of the farm using a fertilizing map and global positioning system. The purpose of this study is to construct and evaluate a map-based variable rate fertilizer system that can be installed on a common fertilizer in Iran to be used as a variable rate system. Materials and methods: In common variable rate fertilizers, the rotational speed change of the distributor shaft is used to apply fertilizers. In this way, a DC motor is assembled on the main shaft of all distributors, which reduces the fertilizing accuracy. The reason for this is that there is no separation for units along the width of the fertilizer. Therefore, we used one DC motor for each distributor and another motor to rotate the agitator in the tank. System Set up: To design and select a suitable engine, the required torque for the rotation distributor shaft was measured by a torque meter and the amount of 2.1 Nm was acquired for that. With regard to the maximum rate of nitrogen fertilizer for land and tractor speed at the time of fertilizing, the order of 350 kg per hectare and 8 km per hour, the maximum distributor shaft speed and power required to rotate distributor shaft were calculated to be 55

  15. Fertilization and early seed formation.

    Science.gov (United States)

    Dumas, Christian; Rogowsky, Peter

    2008-10-01

    The double fertilization of flowering plants is a complex process, encompassing multiple steps. From its discovery more than a century ago, many useful descriptive approaches have been employed to better unveil specific steps/mechanisms. More recently, the development of an in vitro assay developed in our laboratory, has allowed a better understanding of this phenomenon. However, in vitro methods may show some limitations. The search for complementary strategies, especially with the search of mutants affected in the fertilization step allowed one to elucidate this critical and unique phenomenon in living organisms. Genes involved in pollen tube guidance or pollen discharge in synergids have been identified, as well as genes exhibiting differential expression in sperm, egg and central cells before and after fertilization. A calcium wave proved to correspond to the first cellular event seen after cytoplasmic fusion in the fertilized egg cell or zygote, which develops into a multi-cellular organism with an elaborate body plan. The development of the fertilized central cell into a nourishing tissue (endosperm) starts with the formation of the coenocyte, a multinuclear single cell unique in the plant kingdom, cellularization occurring later on. The balance of the paternal and maternal genomes, which is under the control of the FIS polycomb group complex, was found to be of the utmost importance for the successful development of the seed.

  16. Transition cow: interaction with fertility.

    Science.gov (United States)

    Formigoni, A; Trevisi, E

    2003-09-01

    In recent years a progressive worsening of fertility indices in dairy cow herds has been observed. Several factors (genetic, dietary and management) seem to be more related to poor fertility than milk yield level. The degree and the length of the energy deficit during the transition period are inversely related to reproductive indices (e.g. conception rate is fertility in several ways. Excess of rumen degradable proteins, apart from negative energy balance, negatively affects reproductive activity. Conversely, some nutrients (i.e. some polyunsaturated fatty acids or some amino acids) seem to show positive effects on fertility. Finally, the relationship between health status, often compromised during the transition period, and fertility efficiency is discussed. The release of cytokines seems to be related directly and indirectly (mainly by the change in usual hepatic metabolism to the malfunction of reproductive apparatus. Quick recovery of reproductive activity requires the adoption of strategies around calving to cover the higher environmental and nutritive requirements and to prevent disorders of any kind.

  17. Fertility preservation in Turner syndrome.

    Science.gov (United States)

    Grynberg, Michaël; Bidet, Maud; Benard, Julie; Poulain, Marine; Sonigo, Charlotte; Cédrin-Durnerin, Isabelle; Polak, Michel

    2016-01-01

    Premature ovarian insufficiency is a relatively rare condition that can appear early in life. In a non-negligible number of cases the ovarian dysfunction results from genetic diseases. Turner syndrome (TS), the most common sex chromosome abnormality in females, is associated with an inevitable premature exhaustion of the follicular stockpile. The possible or probable infertility is a major concern for TS patients and their parents, and physicians are often asked about possible options to preserve fertility. Unfortunately, there are no recommendations on fertility preservation in this group. The severely reduced follicle pool even during prepubertal life represents the major limit for fertility preservation and is the root of numerous questions regarding the competence of gametes or ovarian tissue crybanked. In addition, patients suffering from TS show higher than usual rates of spontaneous abortion, fetal anomaly, and maternal morbidity and mortality, which should be considered at the time of fertility preservation and before reutilization of the cryopreserved gametes. Apart from fulfillment of the desire of becoming genetic parents, TS patients may be potential candidates for egg donation, gestational surrogacy, and adoption. The present review discusses the different options for preserving female fertility in TS and the ethical questions raised by these approaches.

  18. Male fertility in cystic fibrosis.

    LENUS (Irish Health Repository)

    Chotirmall, S H

    2011-04-05

    Infertility rates among males with cystic fibrosis (CF) approximate 97%. No information is currently available within Ireland determining an understanding of fertility issues and the best methods of information provision to this specialized group. This study aimed to determine understanding and preferred approaches to information provision on fertility issues to Irish CF males. A Descriptive Study utilizing prospective coded questionnaires was mailed to a male CF cohort (n=50). Sections included demographics, fertility knowledge & investigation. Response rate was 16\\/50 (32%). All were aware that CF affected their fertility. More than two-thirds (n=11) were able to provide explanations whilst only one-third (n=5) provided the correct explanation. Significant numbers stated thoughts of marriage and a future family. Half have discussed fertility with a healthcare professional (HCP). Mean age of discussion was 21.9 years. One third preferred an earlier discussion. The commonest first source for information was written material which was also the preferred source. Three-quarters requested further information preferring again, written material. Significant gaps in sex education of Irish CF males exist. Discussion should be initiated by HCPs and centre-directed written material devised to address deficiencies.

  19. Defining risk of prescription opioid overdose: pharmacy shopping and overlapping prescriptions among long-term opioid users in medicaid.

    Science.gov (United States)

    Yang, Zhuo; Wilsey, Barth; Bohm, Michele; Weyrich, Meghan; Roy, Kakoli; Ritley, Dominique; Jones, Christopher; Melnikow, Joy

    2015-05-01

    Use of multiple pharmacies concurrently (pharmacy shopping) and overlapping prescriptions may be indicators of potential misuse or abuse of prescription opioid medications. To evaluate strategies for identifying patients at high risk, we first compared different definitions of pharmacy shopping and then added the indicator of overlapping opioid prescriptions. We identified a cohort of 90,010 Medicaid enrollees who used ≥ 3 opioid prescriptions for ≥ 90 days during 2008 to 2010 from a multistate Medicaid claims database. We compared the diagnostic odds ratios for opioid overdose events of 9 pharmacy shopping definitions. Within a 90-day interval, a threshold of 4 pharmacies had the highest diagnostic odds ratio and was used to define pharmacy shopping. The overdose rate was higher in the subgroup with overlapping prescriptions (18.5 per 1,000 person-years [PYs]) than in the subgroup with pharmacy shopping as the sole indicator (10.7 per 1,000 PYs). Among the subgroup with both conditions, the overdose rate was 26.3 per 1,000 PYs, compared with 4.3 per 1,000 PYs for those with neither condition. Overlapping opioid prescriptions and pharmacy shopping measures had adjusted hazard ratios of 3.0 and 1.8, respectively, for opioid overdose. Using these measures will improve accurate identification of patients at highest risk of opioid overdose, the first step in implementing targeted prevention policies. Long-term prescription opioid use may lead to adverse events, including overdose. Both pharmacy shopping and overlapping opioid prescriptions are associated with adverse outcomes. This study demonstrates that using both indicators will better identify those at high risk of overdose. Published by Elsevier Inc.

  20. Controlled-release NPK fertilizer encapsulated by polymeric membranes.

    Science.gov (United States)

    Jarosiewicz, Anna; Tomaszewska, Maria

    2003-01-15

    The commercial granular fertilizer NPK6-20-30 was coated using polysulfone (PSF), polyacrylonitrile (PAN), and cellulose acetate (CA). The coatings were formed from the polymer solutions by the phase inversion technique. Measurements of the thickness and porosity of the prepared coatings and a microphotographic observation of the coatings were performed. The physical properties of the coatings influence the release rate of macronutrients which are present in the core of the coated fertilizer. In the case of PAN coating with 60.45% porosity, prepared from a 16% polymer solution, 100% of NH(4)(+) and P(2)O(5) was released after 4 h of test and 99.7% of K(+) after 5 h of test, whereas in the case of coating with 48.8% porosity, 31.8% of NH(4)(+), 16.7% of P(2)O(5), and 11.6% of K(+) was released after 5 h. In all experiments, different selectivities of the coatings in terms of the release of components were observed. The release of potassium through the coatings made of PSF and PAN was the slowest. The same tendency was observed for the release of nitrogen through a coating of CA. The release of fertilizer active components was the slowest in the case of PSF. The lowest porosity coating was prepared from the 18% PSF solution.

  1. 羧甲基纤维素接枝丙烯酸/丙烯酰胺缓释肥包膜材料的制备、性能及应用%Preparation of Carboxymethyl Cellulose Graft Acrylic Acid/Acrylamide and Its Application to Coated Urea Slow Release Fertilizer

    Institute of Scientific and Technical Information of China (English)

    徐浩龙

    2012-01-01

    以过硫酸钾为引发剂、N,N'-亚甲基双丙烯酰胺为交联剂,采用水溶液聚合法制备了羧甲基纤维素接枝丙烯酸/丙烯酰胺缓释肥包膜材料,对其吸水性及耐盐性进行了检测,并将其应用于包膜尿素缓释肥的制备.结果表明,在羧甲基纤维素与丙烯酸质量比为3:17、丙烯酰胺用量为12%时,所制备包膜材料在去离子水、自来水和0.4%盐水中的吸水率分别达到743 g.g-1、497 g·g-1和329 g·g-1;包膜尿素缓释肥的氮素释放率满足GB/T 23348- 2009要求,缓释周期达63 d.%Carboxymethyl cellulose graft acrylic acid/acrylamide was prepared by the method of graft copolymerization using potassium persulfate as initiator and N,N'-methylenebisacrylamide as crosslinking agent. The water absorption and salt tolerance of the coating material were determined,and it was applied to preparation of coated urea slow release fertilizer. When the mass ratio of carboxymethyl cellulose to acrylic acid was 3 : 17 and the amount of acrylamide was 12%,the water absorption rate of the coating material was 743 g · g-1,497 g · g-l ,329 g · g-1 in deionized water,tap water,and 0. 4% brine,respectively. The slow-release period of coated urea was 63 d with the nitrogen release rate meeting the standard GB/T-23348-2009.

  2. Crystallographic properties of fertilizer compounds

    Energy Technology Data Exchange (ETDEWEB)

    Frazier, A.W.; Dillard, E.F.; Thrasher, R.D.; Waerstad, K.R.; Hunter, S.R.; Kohler, J.J.; Scheib, R.M.

    1991-02-01

    This bulletin is a compilation of crystallographic data collected at NFERC on 450 fertilizer-related compounds. In TVA's fertilizer R and D program, petrographic examination, XRD, and infrared spectroscopy are combined with conventional chemical analysis methods in identifying the individual compounds that occur in fertilizer materials. This handbook brings together the results of these characterization studies and supplemental crystallographic data from the literature. It is in one-compound-per-page, loose-leaf format, ordered alphabetically by IUPAC name. Indexes provided include IUPAC name, formula, group, alternate formula, synonyms, x-ray data, optical data. Tables are given for solids, compounds in commercial MAP and DAP, and matrix materials in phosphate rock.

  3. [Prescription appropriateness: Indication of citicoline in Primary Care].

    Science.gov (United States)

    Padilla Luz, A; Reyes Rodríguez, J F; Gómez Rodríguez de Acuña, A; González Gómez, C M; Álvarez Dorta, I; Pérez Cánovas, M E

    2015-01-01

    The economic situation has made it necessary to optimize resources by adjusting the pharmaceutical expenditure. Citicoline was (2011) the 10th drug by rank of billed amount. Its approved indications are stroke (acute and sub-acute) and head injury, but not cognitive decline associated with age, the presumed indication for most of its use. To assess the conditions of use of citicoline in the Health Area of Tenerife, in order to detect deviations from the indications of use as stipulated in the prescribing information sheet and the pattern of prescription, with emphasis on the analysis of its use in dementia where currently it has no indication or evidence to support it. Cross-sectional study of prescription-indication. A 680 patient sample, segmented by reference hospital (error±5%; CI: 0.95%; P=0.5) was taken from the 4036 patients with a prescription of citicoline billed during august-october 2011 (obtained from the prescription database program, Farmacanarias). We found that 123 patients (18.1%) had an appropriate indication. By including the prescription regimen, 28 patients (4.1%) had adequate indication and dose levels, and in only 2 patients (0.2%) an appropriate indication, dosage and duration were found. "The correct prescription-indication" of citicoline is inappropiate in almost all patients studied. Impact actions are needed in order to optimize prescription, improve patient safety by reducing potential interactions, and the occurrence of adverse effects, and improve efficiency by promoting savings. Copyright © 2013 Sociedad Española de Médicos de Atención Primaria (SEMERGEN). Publicado por Elsevier España, S.L.U. All rights reserved.

  4. Pediatric emergency department discharge prescriptions requiring pharmacy clarification.

    Science.gov (United States)

    Caruso, Michelle C; Gittelman, Michael A; Widecan, Michelle L; Luria, Joseph W

    2015-06-01

    The aims of the study were to analyze and classify reasons why retail pharmacies need to contact the pediatric emergency department (PED) for clarification on outpatient prescriptions generated using an electronic prescribing system and to categorize the severity of errors captured. A retrospective chart review was conducted at a PED that cares for approximately 92,000 patients annually. All pharmacy callbacks documented in the electronic medical record between August 1, 2008 and July 31, 2009 were included. A datasheet was used to capture patient demographics (age, sex, race, insurance), prescriptions written, and reason for callback. Each call was then assigned a severity level, and time to respond to all calls was estimated. Frequencies were used to analyze the data. A total of 731 errors for 695 callbacks were analyzed from 49,583 prescriptions written at discharge. The most common errors included administrative/insurance issues 342/731 (47%) and prescription writing errors 298/731 (41%). The errors were classified as insignificant (340/729 [47%]), problematic (288/729 [40%]), significant (77/729 [11%]), serious (12/729 [1.64%]), and severe (12/729 [1.64%]). Almost 96% of errant prescriptions were not able to be filled as originally written and required a change by the prescriber. These calls required approximately 127 hours to complete. Prescription errors requiring a pharmacy callback are typically insignificant. However, 13.8% of callbacks about an error were considered significant, serious, or severe. Automated dose checking and verifying insurance coverage of prescribed medications should be considered essential components of prescription writing in a PED.

  5. Fertility potential after unilateral orchiopexy

    DEFF Research Database (Denmark)

    Cortes, D; Thorup, J M; Lindenberg, S

    1996-01-01

    similar fertility potentials were found in adulthood. Five of the 65 patients (7.7%, 95% confidence limits 2.5 to 17%) may experience infertility, representing 33% of both groups with less than 1% of the age matched number of spermatogonia per tubular transverse section (approximately no germ cells......) in the biopsy specimen at orchiopexy. CONCLUSIONS: Between ages 2 and 12 years the timing of unilateral orchiopexy may vary without an effect on subsequent fertility potential. When biopsy at surgery lacks germ cells, there is an approximately 33% age independent risk of subsequent infertility. Otherwise...

  6. A Stata module for computing fertility rates and TFRs from birth histories: tfr2

    Directory of Open Access Journals (Sweden)

    Bruno Schoumaker

    2013-05-01

    Full Text Available BACKGROUND Since the 1970s, birth history data have become widely available, thanks to the World Fertility survey and the Demographic and Health Surveys programs. Despite their wide availability, these data remain under-exploited. Computation, even of simple indicators (fertility rates, total fertility rates, mean age at childbearing and their standard errors, is not direct with such data, and other types of analysis (fertility differentials, reconstruction of fertility trends et cetera may also involve reorganization of data sets and statistical modeling that present a barrier to the use of birth history data. OBJECTIVE This paper presents a Stata software module (tfr2 that was prepared to analyze birth history data in a user-friendly and flexible way. It is designed to be used primarily with DHS data, but can also be used easily with birth histories from other sources. Three types of analysis are performed by tfr2: (1 the computation of age-specific fertility rates and TFRs, as well as their standard errors, (2 the reconstruction of fertility trends, and (3 the estimation of fertility differentials (rate ratios. METHODS The tfr2 module is composed of two parts: (1 a Stata command to transform birth history data into a table of births and exposure (tabexp, and (2 a Poisson regression model to compute fertility rates, fertility trends and fertility differentials from a table of births and exposure (produced by tabexp. COMMENTS One can obtain tfr2 free of charge. It will work with Stata 10 and more recent versions of Stata.

  7. 盐酸左氧氟沙星片处方优化研究%Prescription Study of Levofloxacin Tablets

    Institute of Scientific and Technical Information of China (English)

    刘增平; 黄洁

    2015-01-01

    目的:筛选盐酸左氧氟沙星片的最优处方。方法以溶出度为指标优选处方,溶出度测定方法为转篮法,溶出介质为0.1 mol/L盐酸900 mL,转速为100 r/min。结果优选处方为盐酸左氧氟沙星115.1 g、乳糖43.0 g、微晶纤维素20.0 g、羟丙基纤维素18.0 g、硬脂酸镁为处方用量的1.0%、5%聚维酮K30(50%乙醇)40 mL。结论采用优选处方,颗粒流动性、片剂外观、硬度、脆碎度、崩解时间均符合制剂要求,溶出较完全。%Objective To screen the optimal prescription of Levoflozacin Tablets. Methods The prescription was optimized with the dissolution as the indicator. The dissolution determination adopted the basket method with the dissolution medium of 0. 1 mol/L hydrochloric acid and the rotation speed of 100 r/min. Results The prescription was levoflozacin ( 115. 1 g ) ,lactose ( 43. 0 g ) ,microcrys-talline cellulose ( 20. 0 g ) ,hydrozypropyl cellulose ( 18. 0 g ) ,magnesium stearate 1. 0% of prescription dosage and 5% povidone K30 (50% ethanol)40 mL. Conclusion With this prescription,the granular flowability,tablet appearance,hardness,friability and disintegration time all conform to the requirements of the preparation with complete dissolution.

  8. Soil Fertility Status on Organic Paddy Experiment

    Directory of Open Access Journals (Sweden)

    Mujiyo

    2015-07-01

    Full Text Available The study aims to determine fertility status of the soil after organic paddy experiments using kinds and doses of organic fertilizers. Experiment was conducted at greenhouse laboratory in Faculty of Agriculture Sebelas Maret University Surakarta. Experimental design used completely randomized design with 9 kinds of treatment was replicated 3 times. Experiments were the use of cow manure, Azolla fertilizer, Azolla inoculum and its combinations that are based on fulfilling nutrient requirements of 120 kg N ha-1. Result shows that the use of cow manure, Azolla fertilizers and Azolla inoculum had no effect on changes of soil fertility status. Soil fertility status was not significantly correlated with cow manure (0,16ns, Azolla fertilizer (0,26ns and Azolla inoculum (0,16ns. Average of final soil fertility status included fertile category, which was similar as the initial soil fertility status. Average of final soil properties of treatment but nevertheless was relatively higher than in no treatment, indicating the use of cow manure, Azolla fertilizer, Azolla inoculum and its combinations had greater impact to soil properties. Cow manure despite increased available K2O and dry grain, but it did not significantly increase the soil fertility status from fertile to very fertile. This was presumably due to the relatively short experiment period, only one planting season had not given significant effect to soil properties. Implication of this study is the use of cow manure, Azolla fertilizer, Azolla inoculum and its combinations although did not increase the soil fertility status but could maintain soil fertility status as the initial conditions before planting.

  9. CD9 Expression by Human Granulosa Cells and Platelets as a Predictor of Fertilization Success during IVF

    Directory of Open Access Journals (Sweden)

    Carolyn R. Jaslow

    2010-01-01

    Full Text Available Objective. To determine whether CD9 expression on human granulosa cells (GCs and platelets could predict the success of conventional fertilization of human oocytes during in vitro fertilization (IVF. Methods. Thirty women undergoing IVF for nonmale factor infertility participated. Platelets from venous blood and GCs separated from retrieved oocytes were prepared for immunofluorescence. Flow cytometry quantified the percent of GCs expressing CD9, and CD9 surface density on GCs and platelets. Fertilization rate was determined for the total number of oocytes, and the number of mature oocytes per patient. Correlations tested for significant relationships (P<.05 between fertilization rates and CD9 expression. Results. CD9 surface density on human GCs is inversely correlated with fertilization rate of oocytes (P=.04, but the relationship was weak. Conclusion. More studies are needed to determine if CD9 expression on GCs would be useful for predicting conventional fertilization success during IVF.

  10. Use of a generic protocol in documentation of prescription errors in Estonia, Norway and Sweden

    Directory of Open Access Journals (Sweden)

    Haavik S

    2012-06-01

    Full Text Available Pharmacists have an important role in detecting, preventing, and solving prescription problems, which if left unresolved, may pose a risk of harming the patient.Objective: The objectives of this study were to evaluate the feasibility of a generic study instrument for documentation of prescription problems requiring contact with prescriber before dispensing. The study was organized: 1 by countries: Estonia, Norway and Sweden; 2 by type of prescriptions: handwritten prescriptions, printouts of prescriptions in the electronic medical record and electronically transmitted prescriptions to pharmacies; and 3 by recording method - self-completion by pharmacists and independent observers.Methods: Observational study with independent observers at community pharmacies in Estonia (n=4 and Sweden (n=7 and self-completed protocols in Norway (n=9.Results: Pharmacists’ in Estonia contacted the prescriber for 1.47% of the prescriptions, about 3 times as often as in Norway (0.45% and Sweden (0.38%. Handwritten prescriptions dominated among the problem prescriptions in Estonia (73.2%, printouts of prescriptions in the electronic medical record (89.1% in Norway and electronically transmitted prescriptions to pharmacies (55.9% in Sweden.More administrative errors were identified on handwritten prescriptions and printouts of prescriptions in the electronic medical record in Estonia and in Norway compared with electronically transmitted prescriptions to pharmacies in Sweden (p<0.05 for prescription types and p<0.01 for countries. However, clinically important errors and delivery problems appeared equally often on the different types of prescriptions. In all three countries, only few cases of drug interactions and adverse drug reactions were identified.Conclusion: Despite the different patterns of prescription problems in three countries, the instrument was feasible and can be regarded appropriate to document and classify prescription problems necessitating contact

  11. Predicting prosthetic prescription after major lower-limb amputation.

    Science.gov (United States)

    Resnik, Linda; Borgia, Matthew

    2015-01-01

    We describe prosthetic limb prescription in the first year following lower-limb amputation and examine the relationship between amputation level, geographic region, and prosthetic prescription. We analyzed 2005 to 2010 Department of Veterans Affairs (VA) Inpatient and Medical Encounters SAS data sets, Vital Status death data, and National Prosthetic Patient Database data for 9,994 Veterans who underwent lower-limb amputation at a VA hospital. Descriptive statistics and bivariates were examined. Cox proportional hazard models identified factors associated with prosthetic prescription. Analyses showed that amputation level was associated with prosthetic prescription. The hazard ratios (HRs) were 1.41 for ankle amputation and 0.46 for transfemoral amputation compared with transtibial amputation. HRs for geographic region were Northeast = 1.49, Upper Midwest = 1.26, and West = 1.39 compared with the South (p amputation were most likely to be prescribed a prosthesis and people with transfemoral amputation were least likely. Geographic variation in prosthetic prescription exists in the VA and further research is needed to explain why.

  12. Prescription Opioid Abuse: Challenges and Opportunities for Payers

    Science.gov (United States)

    Katz, Nathaniel P.; Birnbaum, Howard; Brennan, Michael J.; Freedman, John D.; Gilmore, Gary P.; Jay, Dennis; Kenna, George A.; Madras, Bertha K.; McElhaney, Lisa; Weiss, Roger D.; White, Alan G.

    2013-01-01

    Objective Prescription opioid abuse and addiction are serious problems with growing societal and medical costs, resulting in billions of dollars of excess costs to private and governmental health insurers annually. Though difficult to accurately assess, prescription opioid abuse also leads to increased insurance costs in the form of property and liability claims, and costs to state and local governments for judicial, emergency, and social services. This manuscript’s objective is to provide payers with strategies to control these costs, while supporting safe use of prescription opioid medications for patients with chronic pain. Method A Tufts Health Care Institute Program on Opioid Risk Management meeting was convened in June 2010 with private and public payer representatives, public health and law enforcement officials, pain specialists, and other stakeholders to present research, and develop recommendations on solutions that payers might implement to combat this problem. Results While protecting access to prescription opioids for patients with pain, private and public payers can implement strategies to mitigate financial risks associated with opioid abuse, using internal strategies, such as formulary controls, claims data surveillance, and claims matching; and external policies and procedures that support and educate physicians on reducing opioid risks among patients with chronic pain. Conclusion Reimbursement policies, incentives, and health technology systems that encourage physicians to use universal precautions, to consult prescription monitoring program (PMP) data, and to implement Screening, Brief Intervention, and Referral to6Treatment protocols, have a high potential to reduce insurer risks while addressing a serious public health problem. PMID:23725361

  13. RxGen General Optical Model Prescription Generator

    Science.gov (United States)

    Sigrist, Norbert

    2012-01-01

    RxGen is a prescription generator for JPL's in-house optical modeling software package called MACOS (Modeling and Analysis for Controlled Optical Systems), which is an expert optical analysis software package focusing on modeling optics on dynamic structures, deformable optics, and controlled optics. The objectives of RxGen are to simplify and automate MACOS prescription generations, reducing errors associated with creating such optical prescriptions, and improving user efficiency without requiring MACOS proficiency. RxGen uses MATLAB (a high-level language and interactive environment developed by MathWorks) as the development and deployment platform, but RxGen can easily be ported to another optical modeling/analysis platform. Running RxGen within the modeling environment has the huge benefit that variations in optical models can be made an integral part of the modeling state. For instance, optical prescription parameters determined as external functional dependencies, optical variations by controlling the in-/exclusion of optical components like sub-systems, and/or controlling the state of all components. Combining the mentioned capabilities and flexibilities with RxGen's optical abstraction layer completely eliminates the hindering aspects for requiring proficiency in writing/editing MACOS prescriptions, allowing users to focus on the modeling aspects of optical systems, i.e., increasing productivity and efficiency. RxGen provides significant enhancements to MACOS and delivers a framework for fast prototyping as well as for developing very complex controlled optical systems.

  14. Americans' access to prescription drugs stabilizes, 2007-2010.

    Science.gov (United States)

    Boukus, Ellyn R; Carrier, Emily R

    2011-12-01

    Despite the weak economy and more people lacking health insurance, the proportion of Americans reporting problems affording prescription drugs remained level between 2007 and 2010, with more than one in eight going without a prescribed drug in 2010, according to a new national study from the Center for Studying Health System Change (HSC). While remaining stable overall, access to prescription drugs improved for working-age, uninsured people, likely reflecting a decline in visits to health care providers, as well as changes in the composition of the uninsured population. Likewise, elderly people eligible for both Medicare and Medicaid saw a sharp drop in prescription drug access problems. The most vulnerable people--the uninsured, those with low incomes, people in fair or poor health, and those with multiple chronic conditions--continued to face the most unmet prescription needs. For example, 48 percent of uninsured people in fair or poor health went without a prescription drug because of cost concerns in 2010, almost double the rate of insured people with the same reported health status.

  15. Drug prescription appropriateness in the elderly: an Italian study

    Science.gov (United States)

    Allegri, Nicola; Rossi, Federica; Del Signore, Federica; Bertazzoni, Paolo; Bellazzi, Roberto; Sandrini, Giorgio; Vecchi, Tomaso; Liccione, Davide; Pascale, Alessia; Govoni, Stefano

    2017-01-01

    Purpose Correct drug prescription in the elderly is a difficult task that requires careful survey of the current pharmacological therapies. In this article, we reviewed the drug prescriptions provided to 860 persons aged 65 years or over, residing in a small city of Lombardy, Italy. Methods Subjects were recruited from a local nursing home, the Pavia and Vigevano Neuropsychological Center for Alzheimer’s Disease, general practitioners’ offices, and the local University of the Third Age. For each patient, the amount of potentially inappropriate prescriptions (PIPs), sedative and anticholinergic load (SL and AL, respectively), and drug–drug interactions were evaluated. Results Widespread polypharmacy, giving rise to 10.06% of PIPs in the whole collection of prescriptions, was observed. In particular, PIPs mainly concern drugs acting at the central nervous system level, mostly benzodiazepines and antipsychotics. Moreover, approximately one-fourth of the subjects had an elevated SL and approximately one-tenth a high AL. Drug–drug interactions were frequent (266 requiring medical attention), up to five for each single patient. Of concern was the underuse of antidementia drugs: only 20 patients received a cholinesterase inhibitor or memantine, although 183 patients were potentially suitable for this treatment. Conclusion These results demonstrate the need to develop novel strategies aimed at improving the quality of drug prescription. PMID:28228653

  16. Misuse of Prescription Opioid Medication among Women: A Scoping Review.

    Science.gov (United States)

    Hemsing, Natalie; Greaves, Lorraine; Poole, Nancy; Schmidt, Rose

    2016-01-01

    Background. National data from Canada and the United States identify women to be at greater risk than men for the misuse of prescription opioid medications. Various sex- and gender-based factors and patient and physician practices may affect women's use and misuse of prescription opioid drugs. Objectives. To explore the particular risks, issues, and treatment considerations for prescription opioid misuse among women who experience chronic noncancer pain and trauma. Methods. A scoping review for articles published between January 1990 and May 2014 was conducted on sex- and gender-based risks and treatment considerations among women who experience chronic noncancer pain and trauma. Results. A total of 57 articles were identified. The present narrative review summarizes the specific risks for the misuse of prescription opioid medication among women who have experienced violence and trauma, Aboriginal women, adolescents and young women, older women, pregnant women, women of a sexual minority, and transwomen. Discussion. The majority of the literature is descriptive, with few studies that evaluate approaches and interventions to respond to the issue of chronic pain, trauma, and misuse of prescription opioids among women, particularly vulnerable subgroups of women. Conclusions. Trauma-informed and women-centred approaches that address women's vulnerabilities and complex needs require further attention.

  17. Misuse of Prescription Opioid Medication among Women: A Scoping Review

    Directory of Open Access Journals (Sweden)

    Natalie Hemsing

    2016-01-01

    Full Text Available Background. National data from Canada and the United States identify women to be at greater risk than men for the misuse of prescription opioid medications. Various sex- and gender-based factors and patient and physician practices may affect women’s use and misuse of prescription opioid drugs. Objectives. To explore the particular risks, issues, and treatment considerations for prescription opioid misuse among women who experience chronic noncancer pain and trauma. Methods. A scoping review for articles published between January 1990 and May 2014 was conducted on sex- and gender-based risks and treatment considerations among women who experience chronic noncancer pain and trauma. Results. A total of 57 articles were identified. The present narrative review summarizes the specific risks for the misuse of prescription opioid medication among women who have experienced violence and trauma, Aboriginal women, adolescents and young women, older women, pregnant women, women of a sexual minority, and transwomen. Discussion. The majority of the literature is descriptive, with few studies that evaluate approaches and interventions to respond to the issue of chronic pain, trauma, and misuse of prescription opioids among women, particularly vulnerable subgroups of women. Conclusions. Trauma-informed and women-centred approaches that address women’s vulnerabilities and complex needs require further attention.

  18. Fertility potential after unilateral orchiopexy

    DEFF Research Database (Denmark)

    Cortes, D; Thorup, J M; Lindenberg, S

    1996-01-01

    ) in the biopsy specimen at orchiopexy. CONCLUSIONS: Between ages 2 and 12 years the timing of unilateral orchiopexy may vary without an effect on subsequent fertility potential. When biopsy at surgery lacks germ cells, there is an approximately 33% age independent risk of subsequent infertility. Otherwise...

  19. Socioeconomic status and fertility decline

    DEFF Research Database (Denmark)

    Dribe, Martin; Breschi, Marco; Gagnon, Alain

    2017-01-01

    The timings of historical fertility transitions in different regions are well understood by demographers, but much less is known regarding their specific features and causes. In the study reported in this paper, we used longitudinal micro-level data for five local populations in Europe and North ...

  20. Fertility potential after unilateral orchiopexy

    DEFF Research Database (Denmark)

    Cortes, D; Thorup, J M; Lindenberg, S

    1996-01-01

    PURPOSE: We evaluated whether adult fertility potential was better when unilateral orchiopexy was done at ages 2 to 6 years or later, and we identified those at risk for infertility. MATERIALS AND METHODS: Unilateral orchiopexy was performed simultaneously with testicular biopsy in 11 patients 2....

  1. France: High and stable fertility

    Directory of Open Access Journals (Sweden)

    Clémentine Rossier

    2008-07-01

    Full Text Available The current total fertility rate in France is around 1.9 children per woman. This is a relatively high level by current European standards and makes France an outlier, despite the fact that its other demographic trends, especially conjugal behaviour, and social and economic trends are not very different from other Western European countries. France can serve as a counterfactual test case for some of the hypotheses advanced to explain the current low level of fertility in most European countries (delay in fertility, decline in marriage, increased birth control, greater economic uncertainty. France's fertility level can be partly explained by its active family policy introduced after the Second World War, and adapted in the 1980s to accommodate women's entry into the labour force. This policy is the result of a battle, fuelled by pro-natalism, between the conservative supporters of family values and the promoters of state-supported individual equality. French family policy thus encompasses a wide range of measures based on varying ideological backgrounds, and it is difficult to classify in comparison to the more precisely focused family policies of other European welfare states. The active family policy seems to have created especially positive attitudes towards two- or three child families in France.

  2. Strong families and declining fertility

    NARCIS (Netherlands)

    Hilevych, Yuliya

    2016-01-01

    This dissertation focuses on the role of family and social relationships in individuals’ reproductive careers during the fertility decline in Soviet Ukraine from around 1950 to 1975. These three decades after the Second World War signified the end of the First Demographic Transition in Ukraine

  3. The Cost of Raising Fertility

    DEFF Research Database (Denmark)

    Kurjanska, Malgorzata; Lyngsie, Jacob

    supporting an increase in Europe’s fertility rate, increasing maternity leave may also exacerbate gender inequalities tied to childrearing. Relying on alternative measures of in-home gender inequalities (e.g. gender conservatism), initial results provide compelling evidence that maternity benefits do affect...

  4. Fertility potential after unilateral orchiopexy

    DEFF Research Database (Denmark)

    Cortes, D; Thorup, J M; Lindenberg, S

    1996-01-01

    PURPOSE: We evaluated whether adult fertility potential was better when unilateral orchiopexy was done at ages 2 to 6 years or later, and we identified those at risk for infertility. MATERIALS AND METHODS: Unilateral orchiopexy was performed simultaneously with testicular biopsy in 11 patients 2...

  5. (AJST) PEDOLOGICAL CHARACTERISTICS, GENERAL FERTILITY ...

    African Journals Online (AJOL)

    Administrator

    Department of Soil Science, P.O. Box 3008, Morogoro, TANZANIA. 2Graduate ... 3Center for Cooperative Research and Development, Kobe University, ... Key words: Pedological characteristics, fertility, soil classification, benchmark soils, Morogoro. District .... density was determined using core sample method (Blake,.

  6. Mycorrhizas and tropical soil fertility

    NARCIS (Netherlands)

    Cardoso, I.M.; Kuyper, T.W.

    2006-01-01

    Major factors that constrain tropical soil fertility and sustainable agriculture are low nutrient capital, moisture stress, erosion, high P fixation, high acidity with aluminium toxicity, and low soil biodiversity. The fragility of many tropical soils limits food production in annual cropping system

  7. Mycorrhizas and tropical soil fertility

    NARCIS (Netherlands)

    Cardoso, I.M.; Kuyper, T.W.

    2006-01-01

    Major factors that constrain tropical soil fertility and sustainable agriculture are low nutrient capital, moisture stress, erosion, high P fixation, high acidity with aluminium toxicity, and low soil biodiversity. The fragility of many tropical soils limits food production in annual cropping system

  8. Fertilization Mechanisms in Flowering Plants.

    Science.gov (United States)

    Dresselhaus, Thomas; Sprunck, Stefanie; Wessel, Gary M

    2016-02-08

    Compared with the animal kingdom, fertilization is particularly complex in flowering plants (angiosperms). Sperm cells of angiosperms have lost their motility and require transportation as a passive cargo by the pollen tube cell to the egg apparatus (egg cell and accessory synergid cells). Sperm cell release from the pollen tube occurs after intensive communication between the pollen tube cell and the receptive synergid, culminating in the lysis of both interaction partners. Following release of the two sperm cells, they interact and fuse with two dimorphic female gametes (the egg and the central cell) forming the major seed components embryo and endosperm, respectively. This process is known as double fertilization. Here, we review the current understanding of the processes of sperm cell reception, gamete interaction, their pre-fertilization activation and fusion, as well as the mechanisms plants use to prevent the fusion of egg cells with multiple sperm cells. The role of Ca(2+) is highlighted in these various processes and comparisons are drawn between fertilization mechanisms in flowering plants and other eukaryotes, including mammals.

  9. Fertilization Mechanisms in Flowering Plants

    Science.gov (United States)

    Dresselhaus, Thomas; Sprunck, Stefanie; Wessel, Gary M.

    2016-01-01

    Compared to the animal kingdom, fertilization is particularly complex in flowering plants (angiosperms). Sperm cells of angiosperms have lost their motility and require transportation as a passive cargo by the pollen tube cell to the egg apparatus (egg cell and accessory synergid cells). Sperm cell release from the pollen tube occurs after intensive communication between the pollen tube cell and the receptive synergid, culminating in the lysis of both interaction partners. Following release of the two sperm cells they interact and fuse with two dimorphic female gametes (egg and central cell) forming the major seed components embryo and endosperm, respectively. This process is known as double fertilization. Here we review the current understanding of the processes of sperm cell reception, gamete interaction, their pre-fertilization activation and fusion as well as the mechanisms plants use to prevent the fusion of egg cells with multiple sperm cells. The role of Ca2+ is highlighted in these various processes and comparisons are drawn between fertilization mechanisms in flowering plants and other eukaryotes including mammals. PMID:26859271

  10. CURTAILING FERTILIZER SCARCITY AND CLIMATE CHANGE; AN ...

    African Journals Online (AJOL)

    Osondu

    2012-05-29

    May 29, 2012 ... on average thereby using very low rates of chemical fertilizers. Organic materials used by ... The fertilizer issue is more so, considering the current global food ... use profitability through higher commodity prices received by ...

  11. Children Procedures and Treatment (Fertility Issues)

    Medline Plus

    Full Text Available ... Story Share my story! Children Procedures and Treatment Is ovarian tissue cryopreservation available to girls under 18? ... fertility preservation with their cancer-stricken child? How is the Oncofertility Consortium addressing the fertility preservation needs ...

  12. Psychological aspects of male fertility treatment

    DEFF Research Database (Denmark)

    Mikkelsen, Alice Toft; Madsen, Svend Aage; Humaidan, Peter

    2013-01-01

    To explore and to identify the possible need for psychological communicative support in men undergoing fertility treatment.......To explore and to identify the possible need for psychological communicative support in men undergoing fertility treatment....

  13. Fertility preservation after chemotherapy for Hodgkin lymphoma

    NARCIS (Netherlands)

    van der Kaaij, Marleen A. E.; van Echten-Arends, Jannie; Simons, Arnold H. M.; Kluin-Nelemans, Hanneke C.

    2010-01-01

    Treatment for Hodgkin lymphoma can negatively affect fertility. This review summarizes data on fertility after chemotherapy in adult patients. Alkylating chemotherapy, especially if containing procarbazine and/or cyclophosphamide, is most harmful to gonadal functioning. Alkylating regimens cause pro

  14. Understanding fertilization through intracytoplasmic sperm injection (ICSI)

    Science.gov (United States)

    Neri, Queenie V.; Lee, Bora; Rosenwaks, Zev; Machaca, Khaled; Palermo, Gianpiero D.

    2014-01-01

    Summary Since the establishment of in vitro fertilization, it became evident that almost half of the couples failed to achieve fertilization and this phenomenon was attributed to a male gamete dysfunction. The adoption of assisted fertilization techniques particularly ICSI has been able to alleviate male factor infertility by granting the consistent ability of a viable spermatozoon to activate an oocyte. Single sperm injection, by pinpointing the beginning of fertilization, has been an invaluable tool in clarifying the different aspects of early fertilization and syngamy. However, even with ICSI some couples fail to fertilize due to ooplasmic dysmaturity in relation to the achieved nuclear maturation marked by the extrusion of the first polar body. More uncommon are cases where the spermatozoa partially or completely lack the specific oocyte activating factor. In this work, we review the most relevant aspects of fertilization and its failure through assisted reproductive technologies. Attempts at diagnosing and treating clinical fertilization failure are described. PMID:24290744

  15. Waste composting and proving fish for production the organic fertilizers

    Directory of Open Access Journals (Sweden)

    Fernanda San Martins Sanes

    2015-06-01

    Full Text Available The volumes of waste generated in the fishing activity are increasing due to the increase in demand for these products. This implies the need for fast processing and cycling of these materials. Thus, the aim of this study was to evaluate the use of waste generated in the fishing activity as a source of organic fertilizers in agricultural production systems familiar ecological basis. The experiment was conducted at the Experimental Station Cascade / Embrapa Temperate Climate was assessed throughout the composting process and the fermentation of fish waste, identifying the main points that enable the use of these fertilizers in farming systems ecological base. The composting process of rice husk revealed be incomplete during the experiment. The compound prepared with fish waste and exhausted bark of acacia presents itself as a good source of nutrients for crops, which may be suitable as organic fertilizer for production of ecologically-based systems. For liquid organic fertilizer, the conditions under which the experiment was conducted, it is concluded that the compound resulting from aerobic or anaerobic fermentation of fish waste, present themselves as a viable source of nutrients for productive systems of ecological base. However, further studies need to be conducted to better understanding and qualification of both processes.

  16. Socioeconomic Variations in Use of Prescription Medicines for COPD

    DEFF Research Database (Denmark)

    Jacobsen, Ramune; Ekholm, Ola; Rasmussen, Niels K.

    2016-01-01

    BACKGROUND: The purpose of this study was to examine socioeconomic variations in the use of prescription medicines among elderly subjects with COPD. METHODS: Data from the Danish national administrative registers were used. The study population included 1,365 individuals >60 y old residing...... in the Municipality of Copenhagen and diagnosed with COPD in a hospital setting in 2007. Logistic regression analysis was applied to examine the associations between the use of all prescription medicines for obstructive pulmonary diseases and the use of long-acting bronchodilators, in subject groups of different...... socioeconomic position. RESULTS: The study demonstrated that approximately 90% of subjects with COPD purchased at least one prescription medicine for obstructive pulmonary diseases, whereas approximately 50% purchased a long-acting bronchodilator. Medicine use did not vary according to educational status...

  17. Getting to the Root of High Prescription Drug Prices.

    Science.gov (United States)

    Waxman, Henry; Corr, Bill; Martin, Kristi; Duong, Sophia

    2017-07-01

    ISSUE: Historic increases in prescription drug prices and spending are contributing to unsustainable health care costs in the United States. There is widespread public support for elected officials to address the problem. GOAL: To document the drivers of high U.S. prescription drug prices and offer a broad range of feasible policy actions. METHODS: Interviews with experts and organizations engaged with prescription drug development and utilization, pricing, regulation, and clinical practice. Review of policy documents, proposals, and position statements from a variety of stakeholders. FINDINGS AND CONCLUSIONS: Congress and regulators can undertake a wide range of policy actions to begin to rebalance incentives for innovation and price competition, prioritize patient access and affordability, and maximize the availability of information to patients, providers, and payers.

  18. Ramp length/grade prescriptions for wheelchair dependent individuals.

    Science.gov (United States)

    Canale, I; Felici, F; Marchetti, M; Ricci, B

    1991-09-01

    The aim of this work was to provide well defined criteria for ramp construction for wheelchair dependent individuals (WDI). Force capability was measured in a large sample (140) of WDI, who presented different levels of motor impairment. Levels of impairment were established on the basis of the answers given in a questionnaire regarding the degree of self sufficiency at home as well as outside the home and active participation in sports events. Taking into account those WDI who exhibited at least a minimal level of self-sufficiency, the following prescriptions are indicated. For a 1 metre ramp length, allowable maximal incline 15%; up to 3 metre ramp length, maximal incline 10%. The reliability of such prescriptions was confirmed by having a test ramp traversed by 43 WDI. These values are suggested as confidence limits when faced with public building accommodations. Special prescriptions could be adopted for selected populations of WDI.

  19. Drug prescriptions in Danish out-of-hours primary care

    DEFF Research Database (Denmark)

    Christensen, Morten Bondo; Nørøxe, Karen Busk; Moth, Grete

    2016-01-01

    OBJECTIVE: General practitioners are the first point of contact in Danish out-of-hours (OOH) primary care. The large number of contacts implies that prescribing behaviour may have considerable impact on health-care expenditures and quality of care. The aim of this study was to examine...... the prevailing practices for medication prescription in Danish OOH with a particular focus on patient characteristics and contact type. DESIGN AND SETTING: A one-year population-based retrospective observational study was performed of all contacts to OOH primary care in the Central Denmark Region using registry...... data. MAIN OUTCOME MEASURES: Prescriptions were categorised according to Anatomical Therapeutic Chemical Classification (ATC) codes and stratified for patient age, gender and contact type (telephone consultation, clinic consultation or home visit). Prescription rates were calculated as number...

  20. Prescription drug monitoring programs in the United States of America

    Science.gov (United States)

    Félix, Sausan El Burai; Mack, Karin

    2015-01-01

    SYNOPSIS Since the late 1990s, the number of opioid analgesic overdose deaths has quadrupled in the United States of America (from 4 030 deaths in 1999 to 16 651 in 2010). The objectives of this article are to provide an overview of the problem of prescription drug overdose in the United States and to discuss actions that could help reduce the problem, with particular attention to the characteristics of prescription drug monitoring programs (PDMPs). These programs consist of state-level databases that monitor controlled substances. The information compiled in the databases is at the disposal of authorized persons (e.g., physicians, pharmacists, and other health-care providers) and may be used only for professional purposes. Suppliers can use such information to prevent interaction with other drugs or therapeutic duplication, or to identify drug-search behavior. Law enforcement agencies can use these programs to identify improper drug prescription or dispensing patterns, or drug diversion. PMID:25563153

  1. Utilisation of prescription and over-the-counter triptans

    DEFF Research Database (Denmark)

    Frisk, Pia; Kälvemark Sporrong, Sofia; Ljunggren, Gunnar

    2016-01-01

    triptans in Stockholm, Sweden. METHODS: Register data from 4759 patients dispensed triptans in 2014 were used to study documented diagnosis of migraine, concomitant acute and preventive treatment for migraine, and contraindications. Survey data from 49 patients purchasing OTC triptans in three pharmacies...... were used to capture physician-diagnosed migraine, concomitant acute and preventive treatment for migraine, a behaviour of combining or alternating between prescription and OTC triptans, and pharmacy counselling rates. RESULTS: Among the prescription triptan users, 52 % had a recorded diagnosis...... OTC and prescription triptans was rare. Concomitant acute treatment was reported in 53 % and preventive treatment was rare (4 %), despite high self-reported migraine frequencies. Some off-label use was detected, despite moderate to high counselling rates. CONCLUSION: Triptans are prescribed...

  2. Children Procedures and Treatment (Fertility Issues)

    Medline Plus

    Full Text Available ... preservation needs of children? How do cancer and cancer treatment affect a child's fertility? Why should fertility preservation be a priority for my child? How does ovarian tissue cryopreservation differ for children ... What can a girl's cancer doctor do to protect her fertility? What can ...

  3. Air pollution and human fertility rates

    NARCIS (Netherlands)

    Nieuwenhuijsen, Mark J.; Basagaña, Xavier; Dadvand, Payam; Martinez, David; Cirach, Marta; Beelen, Rob; Jacquemin, Bénédicte

    2014-01-01

    Background: Some reports have suggested effects of air pollution on semen quality and success rates of in vitro fertilization (IVF) in humans and lower fertility rates in mice. However, no studies have evaluated the impact of air pollution on human fertility rates. Aims: We assessed the association

  4. Fertilization increases paddy soil organic carbon density

    Institute of Scientific and Technical Information of China (English)

    Shao-xian WANG; Xiao-jun LI; Xin-qiang LIANG; Qi-xiang LUO; Fang FAN; Ying-xu CHEN; Zu-zhang LI; Huo-xi SUN; Tian-fang DAI; Jun-nan WAN

    2012-01-01

    Field experiments provide an opportunity to study the effects of fertilization on soil organic carbon (SOC)sequestration.We sampled soils from a long-term (25 years) paddy experiment in subtropical China.The experiment included eight treatments:(1) check,(2) PK,(3) NP,(4) NK,(5) NPK,(6) 7F:3M (N,P,K inorganic fertilizers+30% organic N),(7) 5F:5M (N,P,K inorganic fertilizers+50% organic N),(8) 3F:7M (N,P,K inorganic fertilizers+70% organic N).Fertilization increased SOC content in the plow layers compared to the non-fertilized check treatment.The SOC density in the top 100 cm of soil ranged from 73.12 to 91.36 Mg/ha.The SOC densities of all fertilizer treatments were greater than that of the check.Those treatments that combined inorganic fertilizers and organic amendments had greater SOC densities than those receiving only inorganic fertilizers.The SOC density was closely correlated to the sum of the soil carbon converted from organic amendments and rice residues.Carbon sequestration in paddy soils could be achieved by balanced and combined fertilization.Fertilization combining both inorganic fertilizers and organic amendments is an effective sustainable practice to sequestrate SOC.

  5. Air pollution and human fertility rates

    NARCIS (Netherlands)

    Nieuwenhuijsen, Mark J.; Basagaña, Xavier; Dadvand, Payam; Martinez, David; Cirach, Marta; Beelen, Rob|info:eu-repo/dai/nl/30483100X; Jacquemin, Bénédicte

    2014-01-01

    Background: Some reports have suggested effects of air pollution on semen quality and success rates of in vitro fertilization (IVF) in humans and lower fertility rates in mice. However, no studies have evaluated the impact of air pollution on human fertility rates. Aims: We assessed the association

  6. [Fertility of black women: conjectures and questions].

    Science.gov (United States)

    Bercovich, A M

    1987-08-01

    Fertility change in Brazil is analyzed using data from censuses from 1940 to 1980 and the PNAD surveys of 1976 and 1984. Topics covered include regional fertility differentials, differences by ethnic group and color, and the impact of educational status on marital fertility. Consideration is given to methodological problems.

  7. Europe the continent with the lowest fertility

    NARCIS (Netherlands)

    Baird, D. T.; Collins, J.; Evers, J. L. H.; Leridon, H.; Lutz, W.; Velde, E. Te; Thevenon, O.; Crosignani, P. G.; Devroey, P.; Diedrich, K.; Fauser, B. C. J. M.; Fraser, L.; Geraedts, J. P. M.; Gianaroli, L.; Glasier, A.; Sunde, A.; Tarlatzis, B.; Van Steirteghem, A.; Veiga, A.

    2010-01-01

    INTRODUCTION: Although fertility rates are falling in many countries, Europe is the continent with the lowest total fertility rate (TFR). This review assesses trends in fertility rates, explores possible health and social factors and reviews the impact of health and social interventions designed to

  8. Fertilization increases paddy soil organic carbon density.

    Science.gov (United States)

    Wang, Shao-xian; Liang, Xin-qiang; Luo, Qi-xiang; Fan, Fang; Chen, Ying-xu; Li, Zu-zhang; Sun, Huo-xi; Dai, Tian-fang; Wan, Jun-nan; Li, Xiao-jun

    2012-04-01

    Field experiments provide an opportunity to study the effects of fertilization on soil organic carbon (SOC) sequestration. We sampled soils from a long-term (25 years) paddy experiment in subtropical China. The experiment included eight treatments: (1) check, (2) PK, (3) NP, (4) NK, (5) NPK, (6) 7F:3M (N, P, K inorganic fertilizers+30% organic N), (7) 5F:5M (N, P, K inorganic fertilizers+50% organic N), (8) 3F:7M (N, P, K inorganic fertilizers+70% organic N). Fertilization increased SOC content in the plow layers compared to the non-fertilized check treatment. The SOC density in the top 100 cm of soil ranged from 73.12 to 91.36 Mg/ha. The SOC densities of all fertilizer treatments were greater than that of the check. Those treatments that combined inorganic fertilizers and organic amendments had greater SOC densities than those receiving only inorganic fertilizers. The SOC density was closely correlated to the sum of the soil carbon converted from organic amendments and rice residues. Carbon sequestration in paddy soils could be achieved by balanced and combined fertilization. Fertilization combining both inorganic fertilizers and organic amendments is an effective sustainable practice to sequestrate SOC.

  9. Determinants of Fertility Differential in Korea.

    Science.gov (United States)

    Shin, Eui Hang; And Others

    1981-01-01

    Analyzes the causal relationships of the fertility differentials of 2200 married women in a small Korean town. Notes the effect on fertility of socioeconomic status, age at first marriage, family background, and various family planning strategies (contraception, abortion). Discusses a process model on fertility. (Author/SB)

  10. 7 CFR 2902.22 - Fertilizers.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 15 2010-01-01 2010-01-01 false Fertilizers. 2902.22 Section 2902.22 Agriculture... Fertilizers. (a) Definition. Products formulated or processed to provide nutrients for plant growth and/or beneficial bacteria to convert nutrients into plant usable forms. Biobased fertilizers, which are likely...

  11. Abortion Legalization and Life-Cycle Fertility

    Science.gov (United States)

    Ananat, Elizabeth Oltmans; Gruber, Jonathan; Levine, Phillip

    2007-01-01

    The early-1970s abortion legalization led to a significant drop in fertility. We investigate whether this decline represented a delay in births or a permanent reduction in fertility. We combine Census and Vital Statistics data to compare the lifetime fertility of women born in early-legalizing states, whose peak childbearing years occurred in the…

  12. Drug prescription appropriateness in the elderly: an Italian study

    Directory of Open Access Journals (Sweden)

    Allegri N

    2017-02-01

    Full Text Available Nicola Allegri,1 Federica Rossi,2 Federica Del Signore,2 Paolo Bertazzoni,3 Roberto Bellazzi,4 Giorgio Sandrini,5 Tomaso Vecchi,1 Davide Liccione,1 Alessia Pascale,6 Stefano Govoni6 1Department of Brain and Behavioral Sciences, University of Pavia, 2Pavia and Vigevano Neuropsychological Center for Alzheimer’s Disease, 3”Bertazzoni” Pharmacy General Partnership, Vigevano, 4Nephrology and Dialysis Ward, Civil Hospital of Vigevano, 5C. Mondino National Institute of Neurology Foundation, IRCCS, 6Department of Drug Sciences, Section of pharmacology, University of Pavia, Pavia, Italy Purpose: Correct drug prescription in the elderly is a difficult task that requires careful survey of the current pharmacological therapies. In this article, we reviewed the drug prescriptions provided to 860 persons aged 65 years or over, residing in a small city of Lombardy, Italy.Methods: Subjects were recruited from a local nursing home, the Pavia and Vigevano Neuropsychological Center for Alzheimer’s Disease, general practitioners’ offices, and the local University of the Third Age. For each patient, the amount of potentially inappropriate prescriptions (PIPs, sedative and anticholinergic load (SL and AL, respectively, and drug–drug interactions were evaluated.Results: Widespread polypharmacy, giving rise to 10.06% of PIPs in the whole collection of prescriptions, was observed. In particular, PIPs mainly concern drugs acting at the central nervous system level, mostly benzodiazepines and antipsychotics. Moreover, approximately one-fourth of the subjects had an elevated SL and approximately one-tenth a high AL. Drug–drug interactions were frequent (266 requiring medical attention, up to five for each single patient. Of concern was the underuse of antidementia drugs: only 20 patients received a cholinesterase inhibitor or memantine, although 183 patients were potentially suitable for this treatment.Conclusion: These results demonstrate the need to develop

  13. Prescription opioid analgesics increase the risk of depression.

    Science.gov (United States)

    Scherrer, Jeffrey F; Svrakic, Dragan M; Freedland, Kenneth E; Chrusciel, Timothy; Balasubramanian, Sumitra; Bucholz, Kathleen K; Lawler, Elizabeth V; Lustman, Patrick J

    2014-03-01

    Prescription opioid analgesic use has quintupled recently. Evidence linking opioid use with depression emanates from animal models and studies of persons with co-occurring substance use and major depression. Little is known about depressogenic effects of opioid use in other populations. The purpose of this study was to determine whether prescription opioids are associated with increased risk of diagnosed depression. Retrospective cohort study, new user design. Medical record data from 49,770 US Department of Veterans Affairs (VA) health care system patients with no recent (24-month) history of opioid use or a diagnosis of depression in 1999 and 2000. Propensity scores were used to control for bias by indication, and the data were weighted to balance the distribution of covariates by duration of incident opioid exposure. Cox proportional hazard models with adjustment for painful conditions were used to estimate the association between duration of prescription opioid use and the subsequent risk of development of depression between 2001 and 2007. Of 49,770 patients who were prescribed an opioid analgesic, 91 % had a prescription for 180 days. Compared to patients whose prescription was for opioid prescription increased (HR = 1.25; 95 % CI: 1.05-1.46 for 90-180 days, and HR = 1.51; 95 % CI:1.31-1.74 for > 180 days). In this sample of veterans with no recent (24-month) history of depression or opioid analgesic use, the risk of development of depression increased as the duration of opioid analgesic exposure increased. The potential for depressogenic effect should be considered in risk-benefit discussions, and patients initiating opioid treatment should be monitored for development of depression.

  14. Potential misuse and inappropriate prescription practices involving opioid analgesics.

    Science.gov (United States)

    Liu, Ying; Logan, Joseph E; Paulozzi, Leonard J; Zhang, Kun; Jones, Christopher M

    2013-08-01

    Opioid misuse and abuse are growing concerns among the medical and public health communities. To examine the prevalence of indicators for potential opioid misuse in a large, commercially insured adult population. We adapted existing indicators developed by expert panels to include having overlapping opioid prescriptions, overlapping opioid and benzodiazepine prescriptions, long-acting/ extended release (LA/ER) opioids for acute pain,and high daily doses of opioids (>100 morphine milligram equivalents). These indicators were assessed among continuously enrolled individuals aged 18-64 years from the 2009 Truven Health MarketScan databases. Analyses were stratified by sex. We identified 3,391,599 eligible enrollees who received at least 1 opioid prescription. On average, enrollees obtained 3.3 opioid prescriptions, and the average annual days of supply was 47 days. Twice as many enrollees received opioid prescriptions for acute pain as for chronic pain. About a quarter of the enrollees had at least 1 indicator of either potential misuse by patients or inappropriate prescription practices by providers. About 15% of enrollees had high daily doses;7.8% had opioid overlap; and 7.9% had opioid and benzodiazepine overlap. Among those prescribed LA/ER opioids, 24.3% were treated for acute pain. Overlap indicators were more common among women. Our findings underscore the critical need to develop programs aimed at promoting appropriate use of opioids. Retrospective opioid utilization reviews similar to our analyses can potentially help managed care organizations and healthcare providers improve patient care and reduce the risk of adverse outcomes related to these medications.

  15. Prescription Opioid Analgesics Commonly Unused After Surgery: A Systematic Review.

    Science.gov (United States)

    Bicket, Mark C; Long, Jane J; Pronovost, Peter J; Alexander, G Caleb; Wu, Christopher L

    2017-08-02

    Prescription opioid analgesics play an important role in the treatment of postoperative pain; however, unused opioids may be diverted for nonmedical use and contribute to opioid-related injuries and deaths. To quantify how commonly postoperative prescription opioids are unused, why they remain unused, and what practices are followed regarding their storage and disposal. MEDLINE, EMBASE, and Cochrane Central Register of Controlled Trials were searched from database inception to October 18, 2016, for studies describing opioid oversupply for adults after a surgical procedure. The primary outcome-opioid oversupply-was defined as the number of patients with either filled but unused opioid prescriptions or unfilled opioid prescriptions. Two reviewers independently screened studies for inclusion, extracted data, and assessed the study quality. Six eligible studies reported on a total of 810 unique patients (range, 30-250 patients) who underwent 7 different types of surgical procedures. Across the 6 studies, 67% to 92% of patients reported unused opioids. Of all the opioid tablets obtained by surgical patients, 42% to 71% went unused. Most patients stopped or used no opioids owing to adequate pain control, and 16% to 29% of patients reported opioid-induced adverse effects. In 2 studies examining storage safety, 73% to 77% of patients reported that their prescription opioids were not stored in locked containers. All studies reported low rates of anticipated or actual disposal, but no study reported US Food and Drug Administration-recommended disposal methods in more than 9% of patients. Postoperative prescription opioids often go unused, unlocked, and undisposed, suggesting an important reservoir of opioids contributing to nonmedical use of these products, which could cause injuries or even deaths.

  16. Regional variation in infant hypoallergenic formula prescriptions in Australia.

    Science.gov (United States)

    Mullins, Raymond J; Clark, Sunday; Camargo, Carlos A

    2010-03-01

    There is little information on the regional distribution of food allergy in Australia. We examined the influence of latitude (a marker of sunlight/vitamin D status) on food allergy, as measured by 2007 infant hypoallergenic formula (IHF) prescription rates in children ages 0-2 yrs. Data were compiled from the 52 statistical divisions in mainland Australia plus the island of Tasmania (n=53 observations). Data from the Australian Department of Health and Aging and the Australian Bureau of Statistics were analysed by statistical division. There was significant regional variability in hypoallergenic formula prescription rates (per 100,000 population/yr), with the highest rates in southern Australia (14,406) and the lowest in the north (721), compared with a national average of 4099. Geographical factors (decreasing latitude and increasing longitude) were associated with a higher rate of IHF prescriptions, such that rates were higher in southern vs. northern regions, and in eastern compared with western regions. Controlling for longitude, physician density and markers of socioeconomic status, southern latitudes were associated with higher hypoallergenic formulae prescription rates [beta, -147.98; 95% confidence interval (CI)=-281.83 to -14.14; p=0.03]. Controlling for latitude, physician density and markers of socioeconomic status, eastern longitudes were also associated with higher hypoallergenic formulae prescription rates (beta, 89.69; 95% CI=2.90-176.49; p=0.04). Among young children, hypoallergenic formula prescription rates are more common in the southern and eastern regions of Australia. These data provide support for a possible role of sun exposure/vitamin D status (amongst other potential factors) in the pathogenesis of food allergy.

  17. Electronic prescription as contributing factor for hospitalized patients' safety.

    Directory of Open Access Journals (Sweden)

    Gimenes FRE

    2006-03-01

    Full Text Available The following study was performed to identify factors related to medication errors in the computerized physician order entry and their advantages and disadvantages according to doctors, nursing team and administrative officers. It is a survey descriptive study carried out at three units of a Brazilian academic hospital in the southeast area. The study was divided in two phases. In the first phase, we analyzed a total of 1,349 prescriptions from general medical unit, surgical and orthopaedic wards during 30 days consecutively. A semi-structured instrument, elaborated by a group of researchers for the study proposals, was used. In the second phase, a semi-structured questionnaire was applied to the health professionals containing closed and open items approaching their opinion about the composition of electronic prescription, the advantages and disadvantages of them, and their suggestions for its improvement. Out of 1,349 prescriptions observed, 17.5% presented deletions, 25.0% medicines written manually and 17.0% of them were incomplete. Some of the advantages pointed by health professionals were its legibility (37.5%, little time spent when elaborating and emitting them (20.5% and the way they are a practical and organized (8%. The disadvantages pointed were repetition of previous prescriptions (34%, typing mistakes (17%, dependence on computers (11% and alterations made manually (7%. We conclude, this way, that the computerized prescription order entry represents a great progress among the strategies used to minimize medication errors caused by prescriptions badly formulated. However, it doesn't eradicate the possibility of medication error occurrences, needing some system modifications.

  18. An exercise prescription primer for people with depression.

    Science.gov (United States)

    Stanton, Robert; Happell, Brenda M

    2013-08-01

    A substantial body of evidence supports the value of exercise in the treatment of people with depression. The guidelines for exercise prescription, however, are limited, and based on those developed for healthy populations. This article explores the evidence for exercise in the treatment of depression and the role mental health nurses may play in the delivery of this information. A model of exercise prescription is put forward based on the available evidence and taking into account the challenges faced by mental health nurses and people with depression.

  19. Chiropractors' attitudes toward drug prescription rights: a narrative review.

    Science.gov (United States)

    Emary, Peter Charles; Stuber, Kent Jason

    2014-01-01

    The right to prescribe drugs remains a contentious issue within the chiropractic profession. Nevertheless, drug prescription by manual therapy providers is currently an important topic. Notably, physiotherapists in the United Kingdom were recently granted limited independent prescribing rights. Reports suggest that physiotherapists in Australia now want those same rights, and as such a review of chiropractors' general attitudes toward drug prescription is needed. To examine the literature concerning chiropractors' attitudes toward drug prescription rights and to compare the opinions of chiropractors currently licensed to prescribe medication with those in the profession who are not. This was a narrative review, consisting of a formal literature search and summary of included articles. Electronic databases searched included the Cumulative Index to Nursing and Allied Health Literature, PubMed, and the Index to Chiropractic Literature. Inclusion criteria consisted of prospective studies published in English in peer-reviewed journals. Studies were required to contain data on chiropractors' opinions toward medication prescription rights. Of 33 articles identified, a total of seven surveys were included in the review. Of these, there was a general split in opinion among chiropractors regarding the right to prescribe drugs in chiropractic practice. Those supportive of prescribing rights favoured a limited number of over-the-counter and/or prescription-based medications such as analgesics, anti-inflammatories, and muscle relaxants. When questioned on full prescribing rights, however, chiropractors were generally opposed. In jurisdictions where chiropractors are currently licensed to prescribe from a limited formulary, such as in Switzerland, the majority perceived this right as an advantage for the profession. Moreover, continuing education in pharmacology was viewed as a necessary component of this privilege. Based on the literature to date there is a general split in

  20. Prescription of fixed dose combination drugs for diarrhoea.

    Science.gov (United States)

    Chakrabarti, Amit

    2007-01-01

    Fixed-dose combinations (FDCs) of an antiprotozoal and an antibacterial, for treatment of diarrhoea, have been available in the Indian pharmaceutical market for about a decade. There is little evidence to substantiate this combination therapy. We evaluated 2,163 physician prescriptions for diarrhoea and found that 59 per cent of prescriptions were for FDCs. This is unethical because prescribing such combinations exposes a patient to higher risks of adverse drug reactions and also increases the chances of drug resistance. Physicians' prescribing practices in India are influenced by socioeconomic factors and the pharmaceutical industry's marketing techniques that include giving incentives to physicians to prescribe certain drugs.

  1. Justice implications of a proposed Medicare prescription drug policy.

    Science.gov (United States)

    Larkin, Heather

    2004-07-01

    Social justice is a core value to the mission of social work. Older people are among the most vulnerable populations for whom social workers are called on to advocate. Although Medicare prescription drug coverage has been a top legislative issue over the past few years, such a benefit expansion has yet to be implemented. This article examines the historical context of Medicare and reviews the proposals for prescription drug coverage, identifying the concerns raised. Literature critiquing the justice dimensions of health care for the elderly population is reviewed. Justice claims are identified and refined, and social justice theories are used in the analysis of the proposed policies.

  2. A thermosensitive gel formulation of an empirical traditional Chinese prescription for treating cervical erosion

    Directory of Open Access Journals (Sweden)

    Shuqing Zhou

    2012-10-01

    Full Text Available Cervical erosion, a pathological change associated with chronic cervicitis, is a common condition that is difficult to cure. Many patients particularly those with mild or medium infection and those preparing for pregnancy require a simple but effective medication. In this study, extracts of an empirical herbal prescription composed of six Chinese traditional drugs viz Cortex Phellodendri, Rhizoma Coptidis, Olibanum, Myrrha, borneol and catechu were formulated to facilitate intravaginal administration and improve efficacy. An extract of the first four components was formulated with borneol as a thermosensitive gel (TG while an extract of catechu used to prepare a regular gel (CG because of a chemical incompatibility. The optimized TG was prepared using poloxamer 407 and poloxamer 188. The CG was prepared using glycerin, carbopol and triethanolamine. The gels were characterized in vitro in terms of release of berberine (TG and total catechins (CG and in vivo in a rat model of cervical erosion. Treatment by once daily application of the TG for 7 days followed by once daily application of the CG for 3 days produced a restoration of normal tissues. Gel formulation of the empirical Chinese traditional remedy appears to provide a promising treatment for cervical erosion.

  3. Fertility in female childhood cancer survivors

    DEFF Research Database (Denmark)

    De Bruin, Marie L; Van Dulmen-den Broeder, Eline; Van den Berg, Marleen H

    2009-01-01

    chemotherapy and radiotherapy may have an adverse effect on ovarian function, ovarian reserve and uterine function, clinically leading to sub-fertility, infertility, premature menopause and/or adverse pregnancy outcomes. Here we will first address normal female fertility and methods to detect decreased...... fertility. Hence we will focus on direct effects as well as late fertility-related adverse effects caused by chemotherapy and radiotherapy, and we will conclude with a summary of current options for fertility preservation in female childhood cancer survivors....

  4. Modelling and simulations of controlled release fertilizer

    Science.gov (United States)

    Irfan, Sayed Ameenuddin; Razali, Radzuan; Shaari, Ku Zilati Ku; Mansor, Nurlidia

    2016-11-01

    The recent advancement in controlled release fertilizer has provided an alternative solution to the conventional urea, controlled release fertilizer has a good plant nutrient uptake they are environment friendly. To have an optimum plant intake of nutrients from controlled release fertilizer it is very essential to understand the release characteristics. A mathematical model is developed to predict the release characteristics from polymer coated granule. Numerical simulations are performed by varying the parameters radius of granule, soil water content and soil porosity to study their effect on fertilizer release. Understanding these parameters helps in the better design and improve the efficiency of controlled release fertilizer.

  5. A Research Report on the Prescription Rights of Chinese Nurses

    Institute of Scientific and Technical Information of China (English)

    Shi-Fan Han; Rui-Fang Zhu; Hui-Hui Han

    2015-01-01

    Objective:To explore the feasibility of the nurse’s prescription right in China,to develop the requirements for the qualification of the applicant for the prescription right of nurse,and to determine the content of certain prescriptions in the specific circumstances.Methods:Literature review on the relevant articles/material with the contents of the nurse’ s right of prescription home and abroad.Semi-structured depth interview method was used to interview 18 experts on whether the nurses can participate in the graded nursing decision and whether nurses with certain ability can make the decision.Using the self-made questionnaire "Nurses involved in graded nursing decision-recognition questionnaire",553 nurses completed questionnaires on willingness to nurse decision-making grading.Using the analytic hierarchy process,the 23 experts’ judgment on the main body of the graded nursing was rated.Using semi-structured depth interview method,17 experts were interviewed on the graded nursing quality assessment and training outline.The form of expert personal judgment and the "grading nursing qualification experts predict questionnaire" were used as a preliminary designing tool,32 experts were asked to predict the graded nursing quality.The relatively important factors that might promote implementation of right of Chinese nurse prescribing weights setting were obtained by analytic hierarchy process.Using Delphi method,2 rounds of consultation to 291 experts/times were performed,and determined its content on the fields of graded nursing decision,nurses’ job description,decision making nurse in graded nursing work process and related management system,decision-making main body of clinical nursing,nurse authority of prescription application qualification,clinical nurses,diabetes specialist nurses,tumor specialist nurses,nurses in emergency department,community nurses in certain circumstances writing prescription,and nursing undergraduate added with nurse authority of

  6. A Research Report on the Prescription Rights of Chinese Nurses☆

    Institute of Scientific and Technical Information of China (English)

    Shi-Fan Han; Rui-Fang Zhu; Hui-Hui Han

    2015-01-01

    Objective: To explore the feasibility of the nurse’ s prescription right in China, to develop the requirements for the qualification of the ap-plicant for the prescription right of nurse, and to determine the content of certain prescriptions in the specific circumstances. Methods: Literature review on the relevant articles/material with the contents of the nurse’ s right of prescription home and a-broad. Semi-structured depth interview method was used to interview 18 experts on whether the nurses can participate in the graded nursing decision and whether nurses with certain ability can make the decision. Using the self-made questionnaire“Nur-ses involved in graded nursing decision-recognition questionnaire”, 553 nurses completed questionnaires on willingness to nurse decision-making grading. Using the analytic hierarchy process, the 23 experts’ judgment on the main body of the graded nurs-ing was rated. Using semi-structured depth interview method, 17 experts were interviewed on the graded nursing quality assess-ment and training outline. The form of expert personal judgment and the“grading nursing qualification experts predict question-naire”were used as a preliminary designing tool, 32 experts were asked to predict the graded nursing quality. The relatively im-portant factors that might promote implementation of right of Chinese nurse prescribing weights setting were obtained by analytic hierarchy process. Using Delphi method, 2 rounds of consultation to 291 experts/times were performed, and determined its con-tent on the fields of graded nursing decision, nurses’ job description, decision making nurse in graded nursing work process and related management system, decision-making main body of clinical nursing, nurse authority of prescription application qualifi-cation, clinical nurses, diabetes specialist nurses, tumor specialist nurses, nurses in emergency department, community nurses in certain circumstances writing prescription, and nursing

  7. Effects of organic and chemical fertilizer on plant nutritional status and soil fertility of tomatoes grown under greenhouse condition

    OpenAIRE

    DEMİRTAŞ, Elif Işıl; ÖKTÜREN ASRİ, Filiz; Cevdet Fehmi ÖZKAN; Nuri ARI

    2012-01-01

    The effect of some plant originated liquid organic fertilizer on soil fertility and plant nutritional status of tomato plants were investigated. The experiment was planned to compare the control, organic fertilizer, chemical fertilizer, 1/1chemical+organic fertilizer, ½chemical+organic fertilizer, chemical fertilizer+foliar organic fertilizer application. The trial was conducted in randomised complete block design with four replications. Plant and soil samples were analyzed. According to the ...

  8. Language barriers to prescriptions for patients with limited English proficiency: a survey of pharmacies.

    Science.gov (United States)

    Bradshaw, Michael; Tomany-Korman, Sandra; Flores, Glenn

    2007-08-01

    Twenty-three million Americans have limited English proficiency. Language barriers can have major adverse consequences in health care, but little is known about whether pharmacies provide adequate care to patients with limited English proficiency. We sought to evaluate pharmacies' ability to provide non-English-language prescription labels, information packets, and verbal communication, and assess pharmacies' satisfaction with communication with patients who have limited English proficiency. We used a cross-sectional, mixed-methods survey of Milwaukee County, Wisconsin, pharmacies. Survey questions addressed sociodemographic and language-service characteristics of pharmacies. A pharmacist or technician at each pharmacy was asked 45 questions by telephone, fax, or mail. The main outcome measures were the ability of pharmacies to provide non-English-language prescription labels, information packets, and verbal communication; and pharmacy satisfaction with communication with patients who have limited English proficiency. Of 175 pharmacies, 73% responded. Forty-seven percent of the pharmacies never/only sometimes can print non-English-language prescription labels, 54% never/only sometimes can prepare non-English-language information packets, and 64% never/only sometimes can verbally communicate in non-English languages. Eleven percent use patients' family members/friends to interpret. Only 55% were satisfied with their communication with patients who have limited English proficiency. In multivariate analyses, community pharmacies had significantly lower odds of being able to verbally communicate in non-English languages, whereas pharmacies using telephone interpreting services had significantly higher odds. Pharmacies' suggestions for improving patient communication included continuing education, producing a chain-wide list of resources, hiring bilingual staff, using telephone interpreters, analyzing translation quality/accuracy of labels and information packets, and

  9. Preservation of fertility in children treated for cancer.

    Science.gov (United States)

    Wallace, W H B; Thomson, A B

    2003-06-01

    As treatment for childhood cancer has become increasingly successful, adverse effects on reproductive function are assuming greater importance. Preservation of fertility before treatment must be considered in all young patients at high risk of infertility, and provision of such services requires collaboration between oncology centres and assisted conception units. The UK Children's Cancer Study Group is planning to audit current management of preservation of reproductive function in young patients with cancer, and the British Fertility Society is preparing a voluntary code of best practice to guide and inform clinicians and scientists. Limitation of radiation exposure by shielding of the testes and ovaries should be practiced where possible and sperm banking should be offered to all sexually mature boys at risk of infertility. The rapidly advancing experimental techniques for harvesting of gonadal tissue must be considered and embarked on without unrealistic expectations, although future utilisation of the tissue is unlikely to be realised until the next decade.

  10. Sperm macromolecules associated with bull fertility.

    Science.gov (United States)

    Kaya, Abdullah; Memili, Erdoğan

    2016-06-01

    Bull fertility, ability of the sperm to fertilize and activate the egg that sustain embryo development, is vitally important for effective and efficient production of cattle. Fertility is a complex trait with low heritability. Despite recent advances in genomic selection and possibility of enormous paternal benefits to profitable cattle production, there exist no reliable tests for evaluating semen quality and predicting bull fertility. This review focuses on sperm macromolecules such as transcripts, proteins and the epigenome, i.e., the functional genome that are associated with bull fertility. Generating new information in these systems is important beyond agriculture because such progress advances the fundamental science of the mammalian male gamete while at the same time introduces biotechnology into livestock production. Sperm macromolecules and epigenome markers associated with bull fertility can be used alone or in combination with the current SNP microarrays to determine sperm quality and to indicate bull fertility.

  11. Central stimulants in the treatment of attention-deficit hyperactivity disorder (ADHD) in children and adolescents. A naturalistic study of the prescription in Sweden, 1977-2007.

    Science.gov (United States)

    Janols, Lars-Olof; Liliemark, Jan; Klintberg, Karin; von Knorring, Anne-Liis

    2009-11-01

    An increased prescription of central stimulants (CS) for treatment of attention-deficit hyperactivity disorder (ADHD) in children and adolescents has been reported in Sweden. To follow-up the treatment with CS as concerns total as well as regional differences in prescription rate. Efficacy and side-effects reported and gender differences in prescription over time also have been summarized. Data from the Swedish Medical Products Agency (MPA) of individual licences, annual reports about patients on individual or clinic licences from the MPA and sales statistics from the National Pharmacy (Apoteket AB) have been used. The number of new licences and prescriptions increased dramatically from 1992 to 2007 and a change of preparations was seen. Great differences (fivefold) between the 21 counties of Sweden were noticed. In the follow-up reports to the MPA, a good/moderate treatment effect was reported in 92% and adverse effects were reported in 4% leading to discontinuation of medication in 46% of them. Abuse/misuse of the preparation was suspected in 0.2% of the reports. A tendency of a reduction of the proportion of boys to girls treated through individual licences has been seen. The study, although observational, supports good efficacy, limited adverse effects and a low degree of misuse in clinical use of CS for children and adolescents with ADHD.

  12. Fertility prognosis for infertile couples

    DEFF Research Database (Denmark)

    Bostofte, E; Bagger, P; Michael, A

    1993-01-01

    OBJECTIVE: To develop a fertility prognosis model for infertile couples. DESIGN: Prospective follow-up study. PARTICIPANTS: In the period November 30, 1977 to June 1, 1985, 321 consecutive couples were investigated for infertility at Hvidovre University Hospital. Investigation of the female...... MEASURE: The Cox regression model was used to predict the time required to conceive based on informations provided by fertility investigations. RESULTS: Three of 16 prognostic variables (the period of infertility, the female infertility factor, and the P-test) possess significant prognostic information....... The period of infertility and the P-test are best scored as continuous variables, whereas the female infertility factor are best categorized in four classes, i.e., normal, ovulation or cervical disorder, anatomic disorder, or a combination of disorders. CONCLUSIONS: The three prognostic variables...

  13. Biomediated continuous release phosphate fertilizer

    Science.gov (United States)

    Goldstein, Alan H.; Rogers, Robert D.

    1999-01-01

    A composition is disclosed for providing phosphate fertilizer to the root zone of plants. The composition comprises a microorganism capable of producing and secreting a solubilization agent, a carbon source for providing raw material for the microorganism to convert into the solubilization agent, and rock phosphate ore for providing a source of insoluble phosphate that is solubilized by the solubilization agent and released as soluble phosphate. The composition is provided in a physical form, such as a granule, that retains the microorganism, carbon source, and rock phosphate ore, but permits water and soluble phosphate to diffuse into the soil. A method of using the composition for providing phosphate fertilizer to plants is also disclosed.

  14. Combined fertility and embryotoxicity study.

    Science.gov (United States)

    Reynaud, Lucie; Marsden, Edward

    2013-01-01

    Under normal circumstances, fertility and embryotoxicity studies are run separately according to the ICH S5(R2) guideline for the detection of toxicity to reproduction of medicinal products (1). However, the flexible approach of the S5(R2) guideline also allows the reproduction stages covered in the fertility and embryo-fetal development studies (stages A to D) to be combined into a single study design. The administration period covers the pre-mating and gestation phases through to closure of the hard palate. The principal advantages of the combined study include reductions in the number of animals required and cost. Although the rat is the routine species of choice, the mouse may also be used.

  15. Human Capital, Fertility and Growth

    OpenAIRE

    Galor, Oded

    2006-01-01

    The demographic transition that swept the world in the past 140 years has been identified as one of the prime forces in the transition from stagnation to growth. The unprecedented increase in population growth during the early stages of industrialization was ultimately reversed. The rise in the demand for human capital in the second phase of industrialization brought about a significant reduction in fertility rates and population growth in various regions of the world, enabling economies to c...

  16. The fertility revolution in China.

    Science.gov (United States)

    Vlassoff, C; Shah, I

    1990-10-01

    As a result of a concerted government effort, China has undergone one of the most rapid fertility transitions in history. At present, the 1- child family is the norm in urban areas such as Beijing and Shanghai, while there are an average of 2 children per family in rural areas. There is now concern that this urban-rural discrepancy will lead to serious labor shortages and inadequate family resources to care for the elderly in Chinese cities. Stricter enforcement of the 1-child policy is rural areas, combined with relaxation of fertility disincentives in the cities, may be required. Another concern is the failure of modernization and intensive education to reduce the traditional preference for male children. Over 50% of respondents in fertility surveys express a desire for their first child to be a boy; only 5% prefer a girl. On the other hand, impressive progress has been made in introducing family planning programs in ways that do not assault traditional values. Although the average age at marriage in China--well over 20 years--is similar to that in developed countries, traditional marriage customs, such as co-residence with parents after marriage, remain intact. Similarly, while young people now have greater freedom of choice in the selection of a marriage partner and arranged marriages are now illegal, parents remain an important part of family decision making. Finally, China has not followed the pattern observed in other countries where declining fertility and increased women's status have reduced the extent and duration of breastfeeding. Rather, it appears that the 1 child norm has actually increased the duration of breastfeeding since the last child tends to be nursed for longer periods.

  17. Basics of soil fertility management

    OpenAIRE

    Berner, Alfred

    2013-01-01

    The brochure highlights the soil fertility from various scientific and farming perspectives. Its aims to supplement practical observations of farmers, to encourage them to reconsider their relation to their soil and to practice a truly sustainable soil culture. The booklet tries to achieve this goal by providing information on soil matter such as important soil organisms and soil characteristics like root density, soil structure and alkalinity and by showing possibilities of how to ass...

  18. Molecular aspects of mammalian fertilization

    Institute of Scientific and Technical Information of China (English)

    Hector Serrano; Dolores Garcia-Suarez

    2001-01-01

    Mammalian fertilization is a highly regulated process, much of which are not clearly understood. Here we present some information in order to elaborate a working hypothesis for this process, beginning with the sperm modifications in the epidydimis up to sperm and egg plasmalemma interaction and fusion. We also discuss the still poorly understood capacitation process, the phenomenon of sperm chemo-attraction that brings the capacitated sperm to interact with the oocyte vestments and certain aspects of the acrosome reaction.

  19. User-oriented Understanding of Descriptive, Proscriptive and Prescriptive Lexicography

    DEFF Research Database (Denmark)

    Bergenholtz, Henning

    2003-01-01

    There is much uncertainty and confusion as to the real differences between prescrip-tive and descriptive dictionaries. In general, the majority of existing accounts can be summarised as follows: Descriptive relates to the empirical basis; accordance between the empirical data and the dictionary i...

  20. Antidepressant Prescription and Suicide Rates: Effect of Age and Gender

    Science.gov (United States)

    Kalmar, Sandor; Szanto, Katalin; Rihmer, Zoltan; Mazumdar, Sati; Harrison, Katrin; Mann, J. John

    2008-01-01

    To determine whether the effect of antidepressant exposure on suicide rate is modified by age and gender in Hungary, annual antidepressant prescription rates and suicide rates of about 10 million inhabitants between 1999-2005 were analyzed by age and gender groups. The suicide rate was inversely related to the increased use of antidepressants in…

  1. Scleral Lens Prescription and Management Practices: The SCOPE Study.

    Science.gov (United States)

    Harthan, Jennifer; Nau, Cherie B; Barr, Joseph; Nau, Amy; Shorter, Ellen; Chimato, Nicolette T; Hodge, David O; Schornack, Muriel M

    2017-04-06

    To assess current scleral lens prescription and management practices by conducting an international online survey of eye care providers. The SCOPE (Scleral Lenses in Current Ophthalmic Practice: an Evaluation) study group designed and administered an online survey regarding current scleral lens prescription and management practices. The survey was open from January 15 to March 31, 2015, and generated 723 responses from individuals who had fit at least 5 patients with scleral lenses. Respondents (n=663) prescribed scleral lenses that ranged from 15 to 17 mm in diameter (65%), smaller than 15 mm (18%), and larger than 18 mm (17%). More than 50 lens designs were identified. Average daily wearing time of 11.8 hr was consistent across 651 respondents, and 475/651 (73%) recommended midday removal on some, most, or all days. Most respondents recommended nonpreserved saline to fill the bowl of the lens before application (single-use vials, 392/653 [60%]; bottled products, 372/653 [57%]). A hydrogen peroxide-based disinfection system was the most commonly recommended care product (397/651 [61%]). A reasonable degree of consensus exists regarding some aspects of scleral lens prescription and management (average lens diameter, daily wearing time, and use of nonpreserved products for lens application). Further study is needed to develop evidence-based guidelines for scleral lens prescription and management.

  2. Prescriptions for Educational Reform: Dilemmas of the Real World.

    Science.gov (United States)

    Spaulding, Seth

    1988-01-01

    Explores prescriptions offered for reforming education and the dilemmas they raise. Programs for democratizing education are reviewed with respect to expanding facilities, reforming admission policies, joining teaching and learning, offering experimental courses, and making structural changes. Results of programs for education about democracy and…

  3. Assessment of prescription pattern in asthma therapy at Shamli hospitals.

    Science.gov (United States)

    Srivastava, Rishabh; Sharma, Sanjay; Keshri, Lav; Wal, Pranay

    2012-05-01

    This drug utilization or prescription-monitoring study was conducted to evaluate the drug-prescribing trend of anti-asthmatic drugs in various hospitals (health care centre) of Shamli, (Prabuddha Nagar, Uttar Pradesh, India). The study was conducted in three famous hospitals of Shamli on three hundred thirty (330) patients, using a developed prescription auditing Performa. Data was recorded from the co-operating patients, attending the outpatient department using a chance random sample method for six months by interviewing and information was filled in the performa. The collected data was studied statistically for determining the most prominently prescribed medication for the treatment. The collected information suggested that β-agonist were the most frequently prescribed anti-asthmatic drugs followed by corticosteroids, Methylxanthine, anti-histaminics and leukotriene antagonist. Also the performed prescription analysis revealed that there is significant difference in the prescriptions for multiple drug therapy (90%) as compared to single drug therapy (10%). Also even after the commercial development of pulmonary targeted systems, oral dosage form like tablets (54.93%) were preferred over inhalation (31.69%). Thus, it can be concluded that the present prescribing pattern of antiasthmatics in Shamli does not completely meet standard guidelines for the asthma treatment. Hence there is a need of awareness amongst the physicians of Shamli so that they can follow the guidelines while treating asthma. Also the patients must be encouraged to use newly developed inhalational drug delivery systems for improving the treatment.

  4. Epidemiological study of epilepsy by monitoring prescriptions of antiepileptic drugs.

    Science.gov (United States)

    Banfi, R; Borselli, G; Marinai, C; Borgheresi, A; Cavalieri, A

    1995-07-28

    The aim of this study is to evaluate a simple and effective method of acquiring epidemiological information about epilepsy. Data on antiepileptic drug prescriptions was collected, the utilization pattern being based on defined daily doses (DDDs). Antiepileptic drugs are epidemiological tracers of epilepsy due to their chronic and highly specific usage. Consequently, a prevalence rate for the whole population may be obtained by using DDDs. Data on antiepileptic drug prescriptions for a period of 6 months in 1992 and 6 months in 1993 indicate a utilization of approximately 7 DDDs of antiepileptic drugs per 1,000 inhabitants. The prevalence of epilepsy was estimated by correcting the exposure calculated in DDDs by a factor of 0.68. In our sample, the prevalence of the disease was 5.2 per 1,000 inhabitants in 1992 and 4.9 per 1,000 in 1993. Physician prescriptions were concentrated on four compounds, namely phenobarbital, carbamazepine, valproic acid and phenytoin, which together represented 90% of total antiepileptic drug prescriptions.

  5. Prescription of neuroleptics for children and adolescents in Italy.

    Science.gov (United States)

    Traversa, G; Spila-Alegiani, S; Arpino, C; Ferrara, M

    1998-01-01

    The objective of this study was to describe the use of neuroleptics among children and adolescents in the province of Rome. Subjects 5 to 19 years of age who received neuroleptic prescriptions within the National Health Service between 1986 and 1991 were identified. Prevalence and incidence of use were estimated. The yearly prevalence of use during the study period ranged from 1.3 to 1.7 per 1000 inhabitants. The incidence during 1989 was 1.1 per 1000, with a marked increase with age. Haloperidol was the drug most frequently prescribed; 59.2% of the subjects received only one prescription during the year. Among subjects with more than one prescription, 42.3% received neuroleptics in combination. The observed pattern of use suggests that in current practice neuroleptics are also used for the treatment of nonpsychotic conditions. The analysis of data derived from a prescription monitoring system may provide an important contribution to the description of neuroleptic use among children and adolescents.

  6. 21 CFR 201.100 - Prescription drugs for human use.

    Science.gov (United States)

    2010-04-01

    ..., storage, or wholesale distribution of prescription drugs; or (ii) In the possession of a retail, hospital... without naming their components. (ii) Color additives may be designated as coloring without naming specific color components unless the naming of such components is required by a color additive...

  7. Medical and Nonmedical Users of Prescription Drugs among College Students

    Science.gov (United States)

    Rozenbroek, Katelyn; Rothstein, William G.

    2011-01-01

    Objectives: To examine medical and nonmedical users of prescription opioids, central nervous system depressants, and stimulants taken individually and in combination. Participants: Undergraduates at an urban mid-Atlantic university with 12,000 students. Methods: A questionnaire administered in classes provided 413 responses, with a usable response…

  8. Non-prescription medications: considerations for the dental practitioner.

    Science.gov (United States)

    Kingon, Angus

    2012-04-01

    The widespread availability of non-prescription medications has a significant potential impact on dental practice. Dentists are trained to provide scientifically-based advice on the appropriate use of medications, but it is not uncommon for patients to take matters into their own hands, especially if it is felt that the treatment provided is not solving a specific problem, or is insufficient. Well-meaning but often ill-informed family and friends frequently have an opinion as to what should be done. Not only may the suggested treatment not be effective, it may also be harmful. Over-the-counter medications can easily be obtained, and there is nothing to stop individuals exceeding recommended doses, and if this occurs, there could be adverse medical sequelae. Patient compliance in taking prescription medications is known to be problematic, and when combined with the ready availability of complementary medications, probiotics and illicit drugs, the risk of self-harm can be seen to be a distinct possibility. To compound the position, sometimes there seems to be, in a practical sense, little regulation on the advertising and marketing of non-prescription medications, which can leave consumers not only confused but potentially vulnerable. While complementary medicines may not have a significant role in dental practice in 2012, that may not always be the case as research continues, and reference is made to some aspects of ongoing work. Non-prescription medications are discussed, and some effects on oral health are considered.

  9. Prescribing style and variation in antibiotic prescriptions for sore throat

    DEFF Research Database (Denmark)

    Cordoba Currea, Gloria Cristina; Siersma, Volkert Dirk; Lopez-Valcarcel, Beatriz Gonzalez

    2015-01-01

    Background: Variation in prescription of antibiotics in primary care can indicate poor clinical practice that contributes to the increase of resistant strains. General Practitioners (GPs), as a professional group, are expected to have a fairly homogeneous prescribing style. In this paper, we...

  10. Prescription options for the below knee amputee. A review.

    Science.gov (United States)

    Abrahamson, M A; Skinner, H B; Effeney, D J; Wilson, L A

    1985-02-01

    In 1973 a workshop sponsored by the National Academy of Sciences recommended that "efforts to develop prescription criteria for use of the numerous variants of the BK prosthesis should be intensified." This paper provides a review of the important considerations in the prescription of a below-knee prosthesis. It is intended that this information would assist the physician to make better informed decisions regarding the specific type of prosthesis for a particular patient. No attempt has been made to describe all prosthetic options since a majority of amputees are fit with only a few prescriptions. Thus, socket design, suspension, shank type, and foot specification may be optimized for individual patients through mutual agreement of the prosthetist and the knowledgeable physician. This paper will present some of the more difficult prescription solutions to the various fitting problems that are representative of our nation's amputee population. This is done with the knowledge that there may be other and equally successful solutions to these problems. Several illustrative examples are provided.

  11. ERs May Need to Rethink Opioid Prescription Practices

    Science.gov (United States)

    ... pills, the study showed. "Looking only at the cases analyzed in this study, if all prescriptions written for more than 20 ... be prescribed for ankle sprain at all." The study was scheduled to be ... meeting, in Orlando. Findings presented at meeting are generally viewed as ...

  12. Developing multilingual prescription instructions for patients with limited english proficiency.

    Science.gov (United States)

    Bailey, Stacy Cooper; Hasnain-Wynia, Romana; Chen, Alice Hm; Sarkar, Urmimala; Schoua-Glusberg, Alisu; Lindquist, Lee A; Schillinger, Dean; Wolf, Michael S

    2012-02-01

    This article describes the development of a set of patient-centered prescription medication instructions and their translation into Chinese, Korean, Russian, Spanish, and Vietnamese. Challenges and lessons learned from this process are reported to inform future efforts to develop easy-to-understand, multilingual materials for use in health care settings.

  13. Prescriptions: Hyperrealism and the Chemical Regulation of Mood

    Science.gov (United States)

    Bleakley, Alan; Jolly, Margaretta

    2012-01-01

    Using contemporary literary sources, we explore the powerful ideological framework that normalises prescription dependency as part of everyday life, focusing upon the treatment of mood disorders. Through a literary critical methodology, we read novels by American hyperrealists such as Bret Easton Ellis, David Foster Wallace and Rick Moody as…

  14. Outpatient antibiotic prescriptions from 1992 to 2001 in The Netherlands

    NARCIS (Netherlands)

    Kuyvenhoven, MM; van Balen, FAM; Verheij, TJM

    2003-01-01

    Objectives: Although Dutch outpatient antibiotic prescription rates are low compared with other European countries, continuing to scrutinize trends in outpatient antibiotic use is important in order to identify possible increases in antibiotic use or inappropriate increases in the use of particular

  15. 21 CFR 886.5844 - Prescription spectacle lens.

    Science.gov (United States)

    2010-04-01

    ... for the patient. The device may be modified to protect the eyes from bright sunlight (i.e...) MEDICAL DEVICES OPHTHALMIC DEVICES Therapeutic Devices § 886.5844 Prescription spectacle lens. (a... photosensitized. (b) Classification. Class I (general controls). The device is exempt from the...

  16. Outpatient antibiotic prescriptions from 1992 to 2001 in The Netherlands

    NARCIS (Netherlands)

    Kuyvenhoven, MM; van Balen, FAM; Verheij, TJM

    2003-01-01

    Objectives: Although Dutch outpatient antibiotic prescription rates are low compared with other European countries, continuing to scrutinize trends in outpatient antibiotic use is important in order to identify possible increases in antibiotic use or inappropriate increases in the use of particular

  17. Peer Influence: Use of Alcohol, Tobacco, and Prescription Medications

    Science.gov (United States)

    Varela, Alberto; Pritchard, Mary E.

    2011-01-01

    Objective: Risk-taking behavior (eg, alcohol abuse, tobacco usage, misuse of prescription medications) among college students is a widespread problem. This study focused not only on the frequency of risky health behaviors in college students, but also the companions with whom they engaged in such behaviors. Methods: Three hundred and twelve…

  18. 31 CFR 900.1 - Prescription of standards.

    Science.gov (United States)

    2010-07-01

    ... 31 Money and Finance: Treasury 3 2010-07-01 2010-07-01 false Prescription of standards. 900.1 Section 900.1 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) FEDERAL... policies regarding the classification of debt for accounting purposes (for example, write off...

  19. Buying prescription drugs on the internet: promises and pitfalls.

    Science.gov (United States)

    Weiss, Alan M

    2006-03-01

    Patients can save time and money by purchasing drugs from Internet pharmacies, but they can also end up with counterfeit or substandard medications. Online pharmacies bypass the safeguards of a doctor-patient relationship, creating a dangerous opportunity for prescription drug abuse and unchecked medication interactions and side effects.

  20. A population analysis of prescriptions for asthma medications during pregnancy

    NARCIS (Netherlands)

    Zetstra-van der Woude, Priscilla A.; Vroegop, J. Sebastiaan; Bos, H. Jens; de Jong-van den Berg, Lolkje T. W.

    2013-01-01

    Background: It is important to control asthma during pregnancy. However, some studies indicate that women stop or change their asthma medications when they become pregnant. Objective: We used a population database to analyze changes in prescriptions for asthma medications to patients before, during,

  1. Advertising of antihypertensive medicines and prescription sales in Australia.

    Science.gov (United States)

    Vitry, A; Lai, Y H

    2009-11-01

    Drug promotion is one of the main factors that influence prescribing practices, but there are limited data available to quantify the relationship between drug advertising and prescription sales. To investigate the relationship between advertising for antihypertensive medicines and prescription sales in Australia between 1993 and 2002. Retrospective observational study. Advertising trends were monitored by counting the number of advertisements published in three Australian medical journals. Monthly prescription dispensing data were obtained from Drug Utilisation Sub-Committee and expressed as numbers of defined daily doses/1000 inhabitants/day. Linear regression and cross-correlations of time series were used in the analysis. The drug classes the most heavily advertised, angiotensin-converting enzyme inhibitors and calcium channel blockers, were also the most prescribed during the study period, while the drugs the least advertised, thiazide diuretics and beta-blockers, were the least used. In 5 of the 7 main antihypertensive classes, the product the most advertised was also the most prescribed. Other factors, such as the publication of large clinical trials, may have also influenced prescribing patterns. Prescription sales of antihypertensives in Australia are correlated with promotional advertising. The newest and most expensive medicines may be chosen over older effective drugs by prescribers. New policies on drug promotion control need to be developed.

  2. Exploring University Students' Online Information Seeking about Prescription Medications

    Science.gov (United States)

    Alkhalaf, Ahmad Abdullah

    2013-01-01

    This study explored university students' information seeking behaviors related to prescription medication (PM) information. Specifically, it examined the different sources students use for PM information, their use and perceptions of online sources, the types of PM information they seek, their concerns about, and methods they apply to verify the…

  3. English Grammar Comparison:Descriptive Grammar vs. Prescriptive Grammar

    Institute of Scientific and Technical Information of China (English)

    ZHANG Jing-wen; LI Yi-an

    2015-01-01

    English grammar is thought as one of the most important parts in both language learning and teaching. While few peo⁃ple know there is more than one kind of English grammar. This essay provides the features and comparison between two com⁃monly used English grammar, namely descriptive grammar and prescriptive grammar, and assist English teachers to explore further in grammar teaching.

  4. Adequacy of anti-tuberculosis drug prescriptions in Viet Nam

    DEFF Research Database (Denmark)

    Hoa, N B; Lauritsen, J M; Rieder, H L

    2012-01-01

    SETTING: National Tuberculosis Program, Viet Nam, 2008. OBJECTIVES: To determine drug prescription adherence to national guidelines, to examine factors associated with an erroneous dosage of rifampin (RMP) and to evaluate the impact of an insufficient RMP dosage on treatment outcome. METHODS: A r...

  5. 21 CFR 801.110 - Retail exemption for prescription devices.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Retail exemption for prescription devices. 801.110 Section 801.110 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES LABELING Exemptions From Adequate Directions for Use § 801.110 Retail...

  6. Prosthetic prescription in the Netherlands : an interview with clinical experts

    NARCIS (Netherlands)

    Van Der Linde, H; Geertzen, JHB; Hofstad, CJ; Postema, K

    2004-01-01

    In the process of guideline development for prosthetic prescription in the Netherlands the authors made a study of the daily clinical practice of lower limb prosthetics. Besides the evidence-based knowledge from literature the more implicit knowledge from clinical experts is of importance for guidel

  7. Vitamin D and female fertility.

    Science.gov (United States)

    Lerchbaum, Elisabeth; Rabe, Thomas

    2014-06-01

    Apart from the well known effects of vitamin D on maintaining calcium homeostasis and promoting bone mineralization, there is some evidence suggesting that vitamin D also modulates human reproductive processes. We will review the most interesting and relevant studies on vitamin D and female fertility published over the past year. In the past year, several observational studies reported a better in-vitro fertilization outcome in women with sufficient vitamin D levels (≥30 ng/ml), which was mainly attributed to vitamin D effects on the endometrium. One randomized controlled trial found an increased endometrial thickness in women with polycystic ovary syndrome (PCOS) receiving vitamin D during intrauterine insemination cycles. Further, vitamin D supplementation had a beneficial effect on serum lipids in PCOS women. Vitamin D treatment improved endometriosis in a rat model and increased vitamin D intake was related to a decreased risk of incident endometriosis. Vitamin D was also favorably associated with primary dysmenorrhea, uterine leiomyoma, and ovarian reserve in late reproductive aged women. In women undergoing in-vitro fertilization, a sufficient vitamin D level (≥30 ng/ml) should be obtained. Vitamin D supplementation might improve metabolic parameters in women with PCOS. A high vitamin D intake might be protective against endometriosis.

  8. Multifunctional Environmental Smart Fertilizer Based on l-Aspartic Acid for Sustained Nutrient Release.

    Science.gov (United States)

    Lü, Shaoyu; Feng, Chen; Gao, Chunmei; Wang, Xinggang; Xu, Xiubin; Bai, Xiao; Gao, Nannan; Liu, Mingzhu

    2016-06-22

    Fertilizer is one of the most important elements of modern agriculture. However, conventional fertilizer, when applied to crops, is vulnerable to losses through volatilization, leaching, nitrification, or other means. Such a loss limits crop yields and pollutes the environment. In an effort to enhance nutrient use efficiency and reduce environmental pollution, an environmental smart fertilizer was reported in the current study. Poly(aspartic acid) and a degradable macro-cross-linker based on l-aspartic acid were synthesized and introduced into the fertilizer as a superabsorbent to improve the fertilizer degradability and soil moisture-retention capacity. Sustained release behavior of the fertilizer was achieved in soil. Cumulative release of nitrogen and phosphorus was 79.8% and 64.4% after 30 days, respectively. The water-holding and water-retention capacities of soil with the superabsorbent are obviously higher than those of the control soil without superabsorbent. For the sample of 200 g of soil with 1.5 g of superabsorbent, the water-holding capacity is 81.8%, and the water-retention capacity remains 22.6% after 23 days. All of the current results in this study indicated that the as-prepared fertilizer has a promising application in sustainable modern agriculture.

  9. Potassium Silicate Foliar Fertilizer Grade from Geothermal Sludge and Pyrophyllite

    Directory of Open Access Journals (Sweden)

    Muljani Srie

    2016-01-01

    Full Text Available Potassium silicate fertilizer grade were successfully produced by direct fusion of silica (SiO2 and potasium (KOH and K2CO3 in furnaces at temperatures up to melting point of mixture. The geothermal sludge (98% SiO2 and the pyrophyllite (95% SiO2 were used as silica sources. The purposes of the study was to synthesise potassium silicate fertilizer grade having solids concentrations in the range of 31-37% K2O, and silica in the range of 48-54% SiO2. The weight ratio of silicon dioxide/potasium solid being 1:1 to 5:1. Silica from geothermal sludge is amorphous, whereas pyrophylite is crystalline phase. The results showed that the amount of raw materials needed to get the appropriate molar ratio of potassium silicate fertilizer grade are different, as well as the fusion temperature of the furnace. Potassium silicate prepared from potassium hydroxide and geothermal sludge produced a low molar ratio (2.5: 1 to 3: 1. The potassium required quite small (4:1 in weight ratio, and on a fusion temperature of about 900 °C. Meanwhile, the potassium silicate prepared from pyrophyllite produced a high molar ratio (1.4 - 9.4 and on a fusion temperature of about 1350 °C, so that potassium needed large enough to meet the required molar ratio for the fertilizer grade. The product potassium silicate solid is amorphous with a little trace of crystalline.

  10. Prescription, Description, Reflection: the shape of the software process improvement field

    DEFF Research Database (Denmark)

    Hansen, Bo; Rose, Jeremy; Tjørnehøj, Gitte

    2004-01-01

    in software organisations), or   prescriptive descriptive reflective (theoretically analytical). The field is found to be rather dominated by one approach (the Capability Maturity Model (CMM)) and heavily biased towards prescriptive contributions. Neither of these trends is necessarily beneficial...

  11. prescription pattern of anti-hypertensive drugs in a tertiary health

    African Journals Online (AJOL)

    Emmanuel Ameh

    Objective: This study examined the pattern of physicians' prescription of ... combination therapy, and demonstrate an apparent higher efficacy of calcium channel blocker ... Key words: Antihypertensive, prescription, blood pressure control.

  12. 77 FR 16973 - Direct-to-Consumer Prescription Drug Advertisements; Presentation of the Major Statement in...

    Science.gov (United States)

    2012-03-23

    ... Prescription Drug Advertisements; Presentation of the Major Statement in Television and Radio Advertisements in... determining whether the major statement in direct-to- consumer (DTC) television and radio advertisements... and Benefit Information in Direct-to-Consumer Prescription Drug Television...

  13. Availability of prescription drugs for bipolar disorder at online pharmacies.

    Science.gov (United States)

    Monteith, Scott; Glenn, Tasha; Bauer, Rita; Conell, Jörn; Bauer, Michael

    2016-03-15

    There is increasing use of online pharmacies to purchase prescription drugs. While some online pharmacies are legitimate and safe, there are many unsafe and illegal so-called "rogue" online pharmacies. This study investigated the availability of psychotropic drugs online to consumers in the US, using 5 commonly prescribed drugs for bipolar disorder. Using the search term "buy [drug name]" in the Google, Yahoo and Bing search engines, the characteristics of the online pharmacies found on the first two pages of search results were investigated. The availability of the requested dosage and formulations of two brand (Seroquel XR, Abilify) and three generic drugs (lamotrigine, lithium carbonate and bupropion SR) were determined. Of 30 online pharmacies found, 17 (57%) were rated as rogue by LegitScript. Of the 30 pharmacies, 15 (50%) require a prescription, 21 (70%) claim to be from Canada, with 20 of these having a Canadian International Pharmacy association (CIPA) seal on the website. Only 13 of the 20 sites with a CIPA seal were active CIPA members. There were about the same number of trust verification seals on the rogue and legitimate pharmacy sites. Some rogue pharmacies are professional in appearance, and may be difficult for consumers to recognize as rogue. All five brand and generic drugs were offered for sale online, with or without a prescription. However, many substitutions were presented such as different strengths and formulations including products not approved by the FDA. No evaluation of product quality, packaging or purchasing. Psychotropic medications are available online with or without a prescription. The majority of online pharmacy websites were rogue. Physicians should ask about the use of online pharmacies. For those who choose to use online pharmacies, two measures to detect rogue pharmacies are recommended: (1) only purchase drugs from pharmacies that require a prescription, and (2) check all pharmacy verification seals directly on the website

  14. Frequency of outpatient antibiotic prescription on discharge to hospice care.

    Science.gov (United States)

    Furuno, Jon P; Noble, Brie N; Horne, Kristi N; McGregor, Jessina C; Elman, Miriam R; Bearden, David T; Walsh, Eric W; Fromme, Erik K

    2014-09-01

    The use of antibiotics is common in hospice care despite limited evidence that it improves symptoms or quality of life. Patients receiving antibiotics upon discharge from a hospital may be more likely to continue use following transition to hospice care despite a shift in the goals of care. We quantified the frequency and characteristics for receiving a prescription for antibiotics on discharge from acute care to hospice care. This was a cross-sectional study among adult inpatients (≥18 years old) discharged to hospice care from Oregon Health & Science University (OHSU) from 1 January 2010 to 31 December 2012. Data were collected from an electronic data repository and from the Department of Care Management. Among 62,792 discharges, 845 (1.3%) patients were discharged directly to hospice care (60.0% home and 40.0% inpatient). Most patients discharged to hospice were >65 years old (50.9%) and male (54.6%) and had stayed in the hospital for ≤7 days (56.6%). The prevalence of antibiotic prescription upon discharge to hospice was 21.1%. Among patients discharged with an antibiotic prescription, 70.8% had a documented infection during their index admission. Among documented infections, 40.3% were bloodstream infections, septicemia, or endocarditis, and 38.9% were pneumonia. Independent risk factors for receiving an antibiotic prescription were documented infection during the index admission (adjusted odds ratio [AOR]=7.00; 95% confidence interval [95% CI]=4.68 to 10.46), discharge to home hospice care (AOR=2.86; 95% CI=1.92 to 4.28), and having a cancer diagnosis (AOR=2.19; 95% CI=1.48 to 3.23). These data suggest that a high proportion of patients discharged from acute care to hospice care receive an antibiotic prescription upon discharge.

  15. Fertility issues in the therapy of nonseminomatous testicular tumors.

    Science.gov (United States)

    Lange, P H; Chang, W Y; Fraley, E E

    1987-11-01

    Given the data described herein, there is reason for even greater optimism about the possibility of fertility among patients with testicular cancer. Fertility issues have been and will continue to be important as different therapies for nonseminomatous cancer are proposed. For example, we previously calculated that the difference in fertility between patients who are treated with expectant therapy versus lymph-adenectomy for clinical stage I disease was only 16 patients in favor of expectant therapy. If new data on relapse rates after expectant therapy (e.g., 30 per cent) and better ejaculation preservation rates after lymphadenectomy (e.g., 85 per cent) are incorporated into this calculation, the number benefited falls to 6 patients. It has also been proposed that patients with low-volume stage IIB disease should receive initial chemotherapy and that lymphadenectomy should be reserved for those patients with residual disease. Applying these calculations along with certain additional assumptions, the difference in fertility between these two treatment alternatives is only 4 patients in favor of initial chemotherapy (P.H. Lange; manuscript in preparation). However, this approach has significantly greater toxicity. Much more must be done to improve our understanding and management of infertility in patients with testicular cancer. Additional tasks include the need to establish the exact ratio of patients with testicular cancer who have infertility that precedes or is a result of their disease, and to develop methods for predicting fertility status so that treatment can be tailored accordingly. Also, we must consolidate and improve the indications, techniques, and results for fertility-sparing lymphadenectomy in ways that have been described herein. In addition, the exact damage-to-benefit ratio for the number of courses and types of chemotherapy administered to patients will need to be studied carefully and prospectively, preferably in cooperative groups. The

  16. Liquid Organic Fertilizers for Sustainable Agriculture: Nutrient Uptake of Organic versus Mineral Fertilizers in Citrus Trees

    Science.gov (United States)

    Martínez-Alcántara, Belén; Martínez-Cuenca, Mary-Rus; Bermejo, Almudena; Legaz, Francisco; Quiñones, Ana

    2016-01-01

    The main objective of this study was to compare the performance of two liquid organic fertilizers, an animal and a plant-based fertilizer, with mineral fertilization on citrus trees. The source of the fertilizer (mineral or organic) had significant effect in the nutritional status of the organic and conventionally managed mandarins. Nutrient uptake, vegetative growth, carbohydrate synthesis and soil characteristics were analyzed. Results showed that plants fertilized with animal based liquid fertilizers exhibited higher total biomass with a more profuse development of new developing organs (leaves and fibrous roots). Liquid organic fertilization resulted in an increased uptake of macro and micronutrients compared to mineral fertilized trees. Moreover, organic fertilization positively affected the carbohydrate content (fructose, glucose and sucrose) mainly in summer flush leaves. Liquid organic fertilization also resulted in an increase of soil organic matter content. Animal-based fertilizer, due to intrinsic composition, increased total tree biomass and carbohydrate leaves content, and led to lower soil nitrate concentration and higher P and Mg exchangeable in soil extract compared to vegetal-based fertilizer. Therefore, liquid organic fertilizers could be used as an alternative to traditional mineral fertilization in drip irrigated citrus trees. PMID:27764099

  17. Liquid Organic Fertilizers for Sustainable Agriculture: Nutrient Uptake of Organic versus Mineral Fertilizers in Citrus Trees.

    Science.gov (United States)

    Martínez-Alcántara, Belén; Martínez-Cuenca, Mary-Rus; Bermejo, Almudena; Legaz, Francisco; Quiñones, Ana

    2016-01-01

    The main objective of this study was to compare the performance of two liquid organic fertilizers, an animal and a plant-based fertilizer, with mineral fertilization on citrus trees. The source of the fertilizer (mineral or organic) had significant effect in the nutritional status of the organic and conventionally managed mandarins. Nutrient uptake, vegetative growth, carbohydrate synthesis and soil characteristics were analyzed. Results showed that plants fertilized with animal based liquid fertilizers exhibited higher total biomass with a more profuse development of new developing organs (leaves and fibrous roots). Liquid organic fertilization resulted in an increased uptake of macro and micronutrients compared to mineral fertilized trees. Moreover, organic fertilization positively affected the carbohydrate content (fructose, glucose and sucrose) mainly in summer flush leaves. Liquid organic fertilization also resulted in an increase of soil organic matter content. Animal-based fertilizer, due to intrinsic composition, increased total tree biomass and carbohydrate leaves content, and led to lower soil nitrate concentration and higher P and Mg exchangeable in soil extract compared to vegetal-based fertilizer. Therefore, liquid organic fertilizers could be used as an alternative to traditional mineral fertilization in drip irrigated citrus trees.

  18. Transition of care: A set of pharmaceutical interventions improves hospital discharge prescriptions from an internal medicine ward.

    Science.gov (United States)

    Neeman, Marine; Dobrinas, Maria; Maurer, Sophie; Tagan, Damien; Sautebin, Annelore; Blanc, Anne-Laure; Widmer, Nicolas

    2017-03-01

    Continuity of care between hospitals and community pharmacies needs to be improved to ensure medication safety. This study aimed to evaluate whether a set of pharmaceutical interventions to prepare hospital discharge facilitates the transition of care. This study took place in the internal medicine ward and in surrounding community pharmacies. The intervention group's patients underwent a set of pharmaceutical interventions during their hospital stay: medication reconciliation at admission, medication review, and discharge planning. The two groups were compared with regards to: number of community pharmacist interventions, time spent on discharge prescriptions, and number of treatment changes. Comparison between the groups showed a much lower (77% lower) number of community pharmacist interventions per discharge prescription in the intervention (n=54 patients) compared to the control group (n=64 patients): 6.9 versus 1.6 interventions, respectively (phospital physician. The number of medication changes at different steps was also significantly lower in the intervention group: 40% fewer (phospital admission and discharge, 66% fewer (phospital discharge and community pharmacy care, and 25% fewer (p=0.002) between community pharmacy care and care by a general practitioner. An intervention group underwent significantly fewer medication changes in subsequent steps in the transition of care after a set of interventions performed during their hospital stay. Community pharmacists had to perform fewer interventions on discharge prescriptions. Altogether, this improves continuity of care. Copyright © 2016 European Federation of Internal Medicine. Published by Elsevier B.V. All rights reserved.

  19. Bayesian inference of baseline fertility and treatment effects via a crop yield-fertility model.

    Directory of Open Access Journals (Sweden)

    Hungyen Chen

    Full Text Available To effectively manage soil fertility, knowledge is needed of how a crop uses nutrients from fertilizer applied to the soil. Soil quality is a combination of biological, chemical and physical properties and is hard to assess directly because of collective and multiple functional effects. In this paper, we focus on the application of these concepts to agriculture. We define the baseline fertility of soil as the level of fertility that a crop can acquire for growth from the soil. With this strict definition, we propose a new crop yield-fertility model that enables quantification of the process of improving baseline fertility and the effects of treatments solely from the time series of crop yields. The model was modified from Michaelis-Menten kinetics and measured the additional effects of the treatments given the baseline fertility. Using more than 30 years of experimental data, we used the Bayesian framework to estimate the improvements in baseline fertility and the effects of fertilizer and farmyard manure (FYM on maize (Zea mays, barley (Hordeum vulgare, and soybean (Glycine max yields. Fertilizer contributed the most to the barley yield and FYM contributed the most to the soybean yield among the three crops. The baseline fertility of the subsurface soil was very low for maize and barley prior to fertilization. In contrast, the baseline fertility in this soil approximated half-saturated fertility for the soybean crop. The long-term soil fertility was increased by adding FYM, but the effect of FYM addition was reduced by the addition of fertilizer. Our results provide evidence that long-term soil fertility under continuous farming was maintained, or increased, by the application of natural nutrients compared with the application of synthetic fertilizer.

  20. A Theoretical Approach to Electronic Prescription System: Lesson Learned from Literature Review

    OpenAIRE

    Samadbeik, Mahnaz; Ahmadi, Maryam; Hosseini Asanjan, Seyed Masoud

    2013-01-01

    Context The tendency to use advanced technology in healthcare and the governmental policies have put forward electronic prescription. Electronic prescription is considered as the main solution to overcome the major drawbacks of the paper-based medication prescription, such as transcription errors. This study aims to provide practical information concerning electronic prescription system to a variety of stakeholders. Evidence Acquisition In this review study, PubMed, ISI Web of Science, Scopus...

  1. A Survey of the Studies on Compatible Law of Ingredients in Chinese Herbal Prescriptions

    Institute of Scientific and Technical Information of China (English)

    Wei Guoli; Zheng Xuebao

    2008-01-01

    @@ To prescribe a Chinese herbal prescription for the patient is the main thing done by the doctor in TCM clinic,and also an important link in TCM difierential treatment.The key point in the study of TCM prescriptions is the compatibility of Jaerbal ingredients in a prescription.To reveal the compatible law of TCM prescriptions is an important component part for TCM modernization.The following is a brief account on this kind of studies.

  2. Prescription of high-potency corticosteroid agents and clotrimazole-betamethasone dipropionate by pediatricians.

    Science.gov (United States)

    Fleischer, A B; Feldman, S R

    1999-10-01

    Family physicians, internists, and pediatricians are more likely to prescribe combination topical antifungal-topical corticosteroid preparations than are dermatologists. One such preparation, clotrimazole-betamethasone dipropionate, can cause atrophy because it has a high-potency corticosteroid component. We analyzed data from the National Ambulatory Medical Care Survey for visits to pediatricians from 1990 to 1994 and isolated visits at which a topical corticosteroid agent or clotrimazole-betamethasone dipropionate was prescribed. Pediatricians rarely prescribed single-agent, high-potency topical corticosteroid agents in managing patients with skin disorders. High-potency corticosteroid agents accounted for 5.0% of topical corticosteroid prescriptions, whereas 56.3% were low-potency and 38.7% were medium-potency agents. Of the 696,285 mentions of clotrimazole-betamethasone dipropionate, 56.4% (389,920) were for children aged newborn to 4 years; diagnoses were erythematodesquamatous dermatoses, diaper rash, tinea, well-baby visit, and candidiasis. In contrast, for dermatologists nationwide, no drug mention existed for this combination agent for children aged newborn to 4 years over the 5-year study period. Our results show that clotrimazole-betamethasone dipropionate is prescribed inappropriately by pediatricians, especially in the treatment of young children. Pediatricians rarely use high-potency topical corticosteroid agents, but most of their use of clotrimazole-betamethasone dipropionate is in the youngest children, in whom such corticosteroid use is least appropriate. This prescription pattern suggests that some pediatricians may be unaware that clotrimazole-betamethasone dipropionate has a high-potency cortico steroid component.

  3. Prescription Opioid Abuse, Prescription Opioid Addiction, and Heroin Abuse among Adolescents in a Recovery High School: A Pilot Study

    Science.gov (United States)

    Vosburg, Suzanne K.; Eaton, Thomas A.; Sokolowska, Marta; Osgood, Eric D.; Ashworth, Judy B.; Trudeau, Jeremiah J.; Muffett-Lipinski, Michelle; Katz, Nathaniel P.

    2016-01-01

    The progression from prescription opioid (RXO) abuse to RXO addiction is not well understood in adolescents, nor is the progression from RXO addiction to heroin abuse. The purpose of this pilot study was to characterize the development of RXO drug abuse, RXO drug addiction, and heroin abuse in a small cohort of adolescents recovering from opioid…

  4. Adding a Prescription Drug Benefit to Medicare: An Analysis of the Medicare Prescription Drug, Improvement, and Modernization Act of 2003

    Science.gov (United States)

    2004-09-01

    unpredictable and potentially high costs ( Marmor , 2000). The missing benefit was outpatient prescription drug coverage. On July 30th, President Johnson...Proposed Medicare Benefit At-a-Glance Chart. Retrieved September 12, 2004, from: http://www.kff.org/medicare/ medicarebenefitataglance.cfm Marmor , T.R

  5. Fertility treatment and childhood type 1 diabetes mellitus: a nationwide cohort study of 565,116 live births.

    Science.gov (United States)

    Kettner, Laura Ozer; Matthiesen, Niels Bjerregaard; Ramlau-Hansen, Cecilia Høst; Kesmodel, Ulrik Schiøler; Bay, Bjørn; Henriksen, Tine Brink

    2016-12-01

    To investigate the association between specific types of fertility treatment and childhood type 1 diabetes mellitus. Nationwide birth cohort study. Not applicable. All pregnancies resulting in a live-born singleton child in Denmark from 1995 to 2003. Not applicable. Childhood type 1 diabetes mellitus identified from redeemed prescriptions for insulin until 2013. The study included 565,116 singleton pregnancies. A total of 14,985 children were conceived by ovulation induction or intrauterine insemination, and 8,490 children were conceived by in vitro fertilization or intracytoplasmic sperm injection. During the follow-up period, 2,011 (0.4%) children developed type 1 diabetes mellitus. The primary analyses showed no association between fertility treatment and childhood type 1 diabetes mellitus. In secondary analyses, ovulation induction or intrauterine insemination with follicle-stimulating hormone was associated with an increased risk of type 1 diabetes mellitus (hazard ratio 3.22; 95% confidence interval 1.20 to 8.64). No clear associations were seen with other types of fertility treatment or with specific treatment indications. No association between fertility treatment and childhood type 1 diabetes mellitus was found. Ovulation induction or intrauterine insemination with follicle-stimulating hormone may be associated with an increased risk of childhood type 1 diabetes mellitus. However, this finding may be due to chance or to confounding by indication and thus requires further investigation. Copyright © 2016 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.

  6. EFFECT OF ELECTRIC FERTILIZER ON SOIL PROPERTIES

    Institute of Scientific and Technical Information of China (English)

    WANG Ya-qin; WANG Ji-hong

    2004-01-01

    Electric fertilizer, I. E. Exerting electric field on plants during growing season instead of chemical fertilizer, is a kind of physical fertilizer, and the third kind of fertilizer with developmental prospect after inorganic fertilizer and organic fertilizer. For the purpose of studying the changes of physical and chemical properties of soil after exerting electric field, five treatments with different applications of chemical fertilizer were arranged on the black soil in Yushu City of Jilin Province by randomized block method, and electric field was exerted on plants every ten days during the growing season. Through sample analysis the paper arrives at following conclusions: 1) Exerting electric field can make soil's granular structure increase, bulk density decrease, moisture capacity increase,thus improving the perviousness of soil. 2) Exerting electric field can make microorganism's number increase and activity strengthen, thus activating nutrient and increasing organic matter content. 3) Exerting electric field with 0.1A medium has the best effect. So the chemical fertilizer can be saved. Therefore, we can say that the application of electric fertilizer is favorable for decreasing chemical poison, improving soil, relaxing the contradiction between the supply and demand of chemical fertilizer, and decreasing production cost of agriculture and forestry.

  7. The fertility of internal migrants to Kinshasa.

    Science.gov (United States)

    Anglewicz, Philip; Corker, Jamaica; Kayembe, Patrick

    2017-01-01

    The rapid population growth of many African cities has important implications for population health, yet little is known about factors contributing to increasing population, such as the fertility of internal migrants. We examine whether in-migrants to Kinshasa have different fertility patterns than lifetime Kinshasa residents, and identify characteristics of migrants that may explain differences in fertility. We also use detailed migration histories to examine whether fertility differs by features of migration. We use representative data from the PMA2020 Project for 2197 women in Kinshasa, including 340 women who moved to Kinshasa. We examine differences between migrants and non-migrants in fertility and other fertility-related characteristics. We also examine whether fertility differs by duration of residence in Kinshasa, number of lifetime moves, age at first migration, urban/rural classification of birthplace, and the distinction between intra-Kinshasa migration and migration to Kinshasa.. Migrants have significantly higher fertility than permanent Kinshasa residents, but the difference is relatively small in magnitude. This higher fertility appears due in part to patterns of contraceptive use among migrants. There is noteworthy heterogeneity among migrants: higher fertility among migrants is associated with longer duration in Kinshasa, more lifetime moves, urban-Kinshasa migration, older age at first migration, and moving to Kinshasa from outside (as opposed to intra-Kinshasa migration).

  8. The Effect of a Two-Hour, Room Temperature Incubation of Human Spermatozoa in TEST-Yolk Buffer on the Rate of Fertilization in Vitro

    OpenAIRE

    Jensen, Julie R.; Walker, John H.; Milki, Amin A.; Westphal, Lynn; Behr, Barry

    2004-01-01

    Patients: To reassess the use of TEST-yolk buffer (TYB) in an in vitro fertilization (IVF) program by comparing fertilization rates achieved in a glucose-free cleavage medium by the standard IVF preparation of sperm versus a 2-h, room temperature incubation of sperm in TYB.

  9. Prescription pattern of drugs in pregnancy induced hypertension in a tertiary care hospital

    Directory of Open Access Journals (Sweden)

    Naveen Kumar T

    2013-12-01

    Conclusion: The incidence of single drugs therapy and two drugs was high. Irrational prescriptions were few. The present pattern of prescriptions can be improved by advocating rational drug prescription and awareness regarding safe use of drugs to the obstetricians. [Int J Basic Clin Pharmacol 2013; 2(6.000: 783-787

  10. 76 FR 41434 - Removal of Certain Requirements Related to the Prescription Drug Marketing Act; Opportunity for...

    Science.gov (United States)

    2011-07-14

    ... prescription drug marketing and distribution. The primary purpose of the PDMA was to increase safeguards to... the Prescription Drug Marketing Act; Opportunity for Public Comment AGENCY: Food and Drug... remove a section of the Prescription Drug Marketing Act (PDMA) regulations requiring that prior to...

  11. Linking Annual Prescription Volume of Antidepressants to Corresponding Web Search Query Data: A Possible Proxy for Medical Prescription Behavior?

    Science.gov (United States)

    Gahr, Maximilian; Uzelac, Zeljko; Zeiss, René; Connemann, Bernhard J; Lang, Dirk; Schönfeldt-Lecuona, Carlos

    2015-12-01

    Persons using the Internet to retrieve medical information generate large amounts of health-related data, which are increasingly used in modern health sciences. We analyzed the relation between annual prescription volumes (APVs) of several antidepressants with marketing approval in Germany and corresponding web search query data generated in Google to test whether web search query volume may be a proxy for medical prescription practice. We obtained APVs of several antidepressants related to corresponding prescriptions at the expense of the statutory health insurance in Germany from 2004 to 2013. Web search query data generated in Germany and related to defined search terms (active substance or brand name) were obtained with Google Trends. We calculated correlations (Person's r) between the APVs of each substance and the respective annual "search share" values; coefficients of determination (R) were computed to determine the amount of variability shared by the 2 variables. Significant and strong correlations between substance-specific APVs and corresponding annual query volumes were found for each substance during the observational interval: agomelatine (r = 0.968, R = 0.932, P = 0.01), bupropion (r = 0.962, R = 0.925, P = 0.01), citalopram (r = 0.970, R = 0.941, P = 0.01), escitalopram (r = 0.824, R = 0.682, P = 0.01), fluoxetine (r = 0.885, R = 0.783, P = 0.01), paroxetine (r = 0.801, R = 0.641, P = 0.01), and sertraline (r = 0.880, R = 0.689, P = 0.01). Although the used data did not allow to perform an analysis with a higher temporal resolution (quarters, months), our results suggest that web search query volume may be a proxy for corresponding prescription behavior. However, further studies analyzing other pharmacologic agents and prescription data that facilitate an increased temporal resolution are needed to confirm this hypothesis.

  12. HOMEMADE SLOW-ACTION FERTILIZERS, AS AN ECONOMIC SOLUTION FOR ORGANIC FOOD PRODUCTION

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    Tomasz Ciesielczuk

    2017-03-01

    Full Text Available Organic plant cultivation, especially those intended for human consumption, poses new requirements for gardening. It is recommended to use organic slow-action fertilizers, which provide doses of nutrients essential for plants for a long time. Particularly valuable fertilizers are those that arise within the household, due to their high quality and the absence of costs associated with their purchase and transport. Organic matter contained in the food industry waste or arising in households, in the absence of contamination by other types of waste, can be used for self-production of organic fertilizer. The paper presents the results of testing organic fertilizers, which you can make yourself, destined for the cereal plants. The experimental fertilizers were made from coffee spent grounds (CSG and ash from the thermal conversion of biomass (A, and the components limiting the amount of pests in the form of leaves and flowers of tansy (Tanacetum vulgare L.. The fertilizer can be used at the time of planting and sowing, because of the slow release of nutrients. Moreover, the addition of leaves and flowers of tansy helps to protect the seedling due to the content of essential oils. As a comparison, the horse manure and rabbit droppings fertilizers were used. Such fertilizers can be prepared independently, which leads not only to reducing the weight of biodegradable and mineral waste, but also provides the ability to generate financial savings of the household and promote organic gardening. Fertilizers made from a mixture of CSG and A support the implementation of good agricultural practice and sustainable development.

  13. Antipsychotic prescription and mortality in hospitalized older persons.

    Science.gov (United States)

    Chiesa, Deborah; Marengoni, Alessandra; Nobili, Alessandro; Tettamanti, Mauro; Pasina, Luca; Franchi, Carlotta; Djade, Codjo D; Corrao, Salvatore; Salerno, Francesco; Marcucci, Maura; Romanelli, Giuseppe; Mannucci, Pier Mannuccio

    2017-06-06

    Recent scientific reports have shown that older persons treated with antipsychotics for dementia-related behavioural symptoms have increased mortality. However, the impact of these drugs prescribed during hospitalization has rarely been assessed. We aimed to investigate whether antipsychotics are associated with an increased risk of mortality during hospitalization and at 3-month follow-up in elderly inpatients. We analyzed data gathered during two waves (2010 and 2012) by the REPOSI (Registro Politerapie Società Italiana Medicina Interna). All new prescriptions of antipsychotic drugs during hospitalization, whether maintained or discontinued at discharge, were collected, and logistic regression models were used to analyze their association with in-hospital and 3-month mortality. Covariates were age, sex, the Short Blessed Test (SBT) score, and the Cumulative Illness Rating Scale. Among 2703 patients included in the study, 135 (5%) received new prescriptions for antipsychotic drugs. The most frequently prescribed antipsychotic during hospitalization and eventually maintained at discharge was haloperidol (38% and 36% of cases, respectively). Patients newly prescribed with antipsychotics were older and had a higher Cumulative Illness Rating Scale comorbidity index both at admission and at discharge compared to those who did not receive a prescription. Of those prescribed antipsychotics, 71% had an SBT score ≥10 (indicative of dementia), 12% had an SBT score of 5-9 (indicative of questionable dementia); and 17% had an SBT score <5 (indicative of normal cognition). In-hospital mortality was slightly higher in patients prescribed antipsychotic drugs (14.3% vs 9.4%; P = 0.109), but in multivariate analysis only male sex, older age, and higher SBT scores were significantly related to mortality during hospitalization. At 3-month follow-up, only male sex, older age, and higher SBT scores were associated with mortality. We found that the prescription of antipsychotic

  14. Prescription drug overdose: between patients and their doctors

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    Ling W

    2013-01-01

    Full Text Available Walter Ling,1 Li-Tzy Wu21Department of Psychiatry and Biobehavioral Science, Integrated Substance Abuse Programs, University of California, Los Angeles, CA, USA; 2Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC, USAPrescription drug overdoses, mainly involving prescription opioids, have reached epidemic proportions in the United States over the past 20 years.1,2 Since 2003, prescription opioids have been involved in more drug-related overdose deaths than heroin and cocaine combined. Among patients who were prescribed opioids, an estimated 20% were prescribed high doses of opioids by either single or multiple physicians, and these patients appeared to account for the majority of prescription opioid-related overdoses.1,3,4 The increase in prescription overdose deaths has coincided with a major increase in prescription opioid sales.2 The prescribing practices of some physicians are often believed to have contributed in part to the increase in these overdose deaths. In a recently published perspective, Anna Lembke speculated on why doctors prescribe opioids to known prescription opioid abusers.5 Her article raises a timely and troubling issue for all of us interested in this area of medicine. Lembke identifies the root of the problem to lie in the changing societal attitude towards pain and suffering, the ever-growing availability of opioid medications, the regulatory requirements promulgated, and the perceived shift in the role of the medical professional in this context. Central to her argument is that physicians must now practice according to a set of externally imposed expectations of patients, payers, and regulators, putting the prescriber in the position of being "damned if you do and damned if you don’t". If Lembke is right, the physician now prescribes not according to what he or she wants to do, but according to what he or she must do. The result, at one extreme, is the patient acting as their

  15. Period Fertility in Russia since 1930

    Directory of Open Access Journals (Sweden)

    2002-06-01

    Full Text Available In this paper we present a detailed demographic analysis of the change of period fertility that occurred since 1930, based on individual retrospective data, collected in the most recent (five percent microcensus of the Russian Federation from 1994. We assess the influence of external events on the level and distribution of (period fertility. For the years prior to 1950 our information on age specific fertility is not complete, but using fertility models acceptable estimates can be constructed. The Coale-Trussell model is particularly suited for producing detailed and robust estimates of interpretable parameters of the fertility distribution. Although none of the observed crises in Russia succeeded in exerting a decisive influence on the course of the fertility transition, political events often had profound short-term effects.

  16. Proximate determinants of fertility in Taiwan area.

    Science.gov (United States)

    Lo, S R; Chen, C H

    1987-06-01

    To establish base line data and to evaluate the impacts of induced abortion on fertility in Taiwan before and after legalization, and induced abortion prevalence survey was conducted. 12,516 samples of married women age 15-49 were covered to represent all of Taiwan. Bongaarts' model of proximate determinants of fertility is applied to the survey data to analyze the relationships among total fertility rate, total fecundity, and the indices of the proximate determinants on nonmarriage, contraception, induced abortion, and lacatation. The index of contraception appears to have the greatest (47%) effect on the recent decline of total fertility rate (TFR). Contraception also has the greatest effect on fertility decline among different urbanization areas: 45% for large cities; 46% for urbantownships; and 50% for rural areas. The effects of the proportion of married on the fertility of the 3 areas are 45%, 40%, and 40%, respectively. For induced abortion, the effect is 13% in urban townships and 11% in large cities.

  17. Fertility assurance through extrapair fertilization, and male parental effort.

    Science.gov (United States)

    Fishman, Michael A; Stone, Lewi

    2002-07-01

    Extrapair paternity (EPP) has been observed in many formally monogamous species. Male pursuit of extrapair fertilizations (EPF) is explained by the advantages of having offspring that receive essential paternal care from other males. Because females are capable of exercising a degree of control over the post-copulatory sperm competition, EPP's persistence indicates that females benefit from EPF. Thus, EPP involves cooperation between mated females and extrapair males. On the other hand, mated males exhibit a spectrum of anti-cuckolding strategies. Hence, extrapair attributes of diverse species and populations reported in the literature are particular solutions of evolutionary games involving gender-specific cuckolding/anti-cuckolding strategies. Here we use game theoretical methods to study the effect of male paternal effort conserving strategies in situations where females seek EPF for reasons of genetic compatibility and/or in pursuit of genetic diversity for their offspring. Our results indicate that in these circumstances pursuit of EPF is the only evolutionary stable female strategy. Males, on the other hand, have two, mutually exclusive, evolutionary stable strategies: males that restrict parental care regardless of their mate's fidelity, and males that never restrict parental care. That is, when females seek EPF for reasons of fertility assurance and/or genetic diversity, the conditional male strategy--therein the male's parental efforts are based on his certainty of paternity--loses in competition with the unconditional strategies.

  18. Couples' fertility decision-making

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    Petra Stein

    2014-06-01

    Full Text Available Background: The decision about whether to start a family within a partnership can be viewed as a result of an interaction process. The influence of each of the partners in a couple differs depending on their individual preferences and intentions towards having children. Both of the partners additionally influence each other's fertility intentions and preferences. Objective: We specify, estimate, and test a model that examines the decision about whether to have a child as a choice that is made jointly by the two partners. The transition to the birth of a (further child is investigated with the explicit consideration of both the female partner and the male partner in the partnership context. Methods: An approach for modelling the interactive influences of the two actors in the decision-making process was proposed. A trivariate distribution consisting of both the female and the male partners' fertility intentions, as well as the joint generative decision, was modelled. A multivariate non-linear probit model was chosen and the problem of identification in estimating the relative effects of the actors was resolved. These parameters were used to assess the relative importance of each of the partners' intentions in the decision. We carried out the analysis with MPLUS. Data from the panel of intimate relationships and family dynamics (pairfam was used to estimate the model. Results: The biographical context of each of the partners in relation to their own as well as to their partner's fertility intentions was found to be of considerable importance. Of the significant individual and partner effects, the male partner was shown to have the greater influence. But the female partner was found to have stronger parameters overall and she ultimately has a veto power in the couple's final decision.

  19. A pharmacoepidemiological study of prescription pattern in outpatient clinics in Southwestern Saudi Arabia.

    Science.gov (United States)

    Irshaid, Yacoub M; Al-Homrany, Mohammed A; Hamdi, Anwar A; Adjepon-Yamoah, Keneth K; Mahfouz, Ahmed A

    2004-12-01

    To study the pattern of prescriptions in outpatient clinics in a teaching hospital in Southwestern Saudi Arabia. A total of 3796 prescriptions from outpatient clinics of Aseer Central Hospital, Abha, Kingdom of Saudi Arabia were screened randomly and systemically over one-year period (April 2000 to April 2001). The prescriptions were analyzed for the essential elements of the prescription order, and for the number and classes of drugs prescribed, source of prescription and appropriateness of prescription to the diagnosis. The source of prescriptions was not provided in 61.5% of prescriptions. The diagnosis was missing in 15.1% and not readable in 18.9% of prescriptions. Upper respiratory tract infection (URTI) was the most frequent diagnosis and was included in 21.6% of prescriptions. The average number of drugs per prescription was 2.1 +/- 1.05 (Mean +/- SD), with 90.8% of prescriptions containing 3 or fewer drugs. The most frequently prescribed drugs were nonsteroidal anti-inflammatory drugs (NSAIDs), including paracetamol which were included in 51.2% of prescriptions, followed by antibacterial agents (33.2%). Only 46.4% of prescriptions were appropriate to the diagnosis, while 11.1% were partially appropriate and 5.3% were inappropriate. For the rest (37.2%), it was difficult to evaluate appropriateness due to deficient information. General practitioners and specialists were more likely to prescribe appropriately than emergency room physicians (64.6% and 60.4% versus 35.7%). None of the prescriptions for antiplatelet and anticoagulant drugs and antihypertensive agents were inappropriate. These results emphasize the need for continuing medical education on rational prescribing, and for periodic monitoring of physicians habits on drug utilization.

  20. [Cryptorchism and fertility. Our experience].

    Science.gov (United States)

    Bondavalli, C; Visentini, E; Pegoraro, C; Schiavon, L; Dall'Oglio, B; Parma, A

    1989-09-01

    The relationship between cryptorchidism and fertility has been suggested in a lot of ways but hasn't been clearly demonstrated. In our Institute from 1981 until 1987, 352 orchidopexies had been performed. Out of these, 31 patients were studied with respect to the current age, the age at the surgery, the absence of varicocele and the possible iatrogenic damages. The rate of dispermia among the subjects studied, was 43% whereas 57% had normospermia. 3 out of 4 patients operated for bilateral undescended testis were azoospermic. The volume of unaffected testis is directly related to the health of the seminal status.