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Sample records for preparations include handling

  1. Vestibule and Cask Preparation Mechanical Handling Calculation

    Energy Technology Data Exchange (ETDEWEB)

    N. Ambre

    2004-05-26

    The scope of this document is to develop the size, operational envelopes, and major requirements of the equipment to be used in the vestibule, cask preparation area, and the crane maintenance area of the Fuel Handling Facility. This calculation is intended to support the License Application (LA) submittal of December 2004, in accordance with the directive given by DOE correspondence received on the 27th of January 2004 entitled: ''Authorization for Bechtel SAIC Company L.L.C. to Include a Bare Fuel Handling Facility and Increased Aging Capacity in the License Application, Contract Number DE-AC28-01R W12101'' (Ref. 167124). This correspondence was appended by further correspondence received on the 19th of February 2004 entitled: ''Technical Direction to Bechtel SAIC Company L.L. C. for Surface Facility Improvements, Contract Number DE-AC28-01R W12101; TDL No. 04-024'' (Ref. 16875 1). These documents give the authorization for a Fuel Handling Facility to be included in the baseline. The limitations of this preliminary calculation lie within the assumptions of section 5 , as this calculation is part of an evolutionary design process.

  2. Remote waste handling and feed preparation for Mixed Waste Management

    Energy Technology Data Exchange (ETDEWEB)

    Couture, S.A.; Merrill, R.D. [Lawrence Livermore National Lab., CA (United States); Densley, P.J. [Science Applications International Corp., (United States)

    1995-05-01

    The Mixed Waste Management Facility (MWMF) at the Lawrence Livermore National Laboratory (LLNL) will serve as a national testbed to demonstrate mature mixed waste handling and treatment technologies in a complete front-end to back-end --facility (1). Remote operations, modular processing units and telerobotics for initial waste characterization, sorting and feed preparation have been demonstrated at the bench scale and have been selected for demonstration in MWMF. The goal of the Feed Preparation design team was to design and deploy a robust system that meets the initial waste preparation flexibility and productivity needs while providing a smooth upgrade path to incorporate technology advances as they occur. The selection of telerobotics for remote handling in MWMF was made based on a number of factors -- personnel protection, waste generation, maturity, cost, flexibility and extendibility. Modular processing units were selected to enable processing flexibility and facilitate reconfiguration as new treatment processes or waste streams are brought on line for demonstration. Modularity will be achieved through standard interfaces for mechanical attachment as well as process utilities, feeds and effluents. This will facilitate reconfiguration of contaminated systems without drilling, cutting or welding of contaminated materials and with a minimum of operator contact. Modular interfaces also provide a standard connection and disconnection method that can be engineered to allow convenient remote operation.

  3. Preparing the perfect cuttlefish meal: complex prey handling by dolphins.

    Directory of Open Access Journals (Sweden)

    Julian Finn

    Full Text Available Dolphins are well known for their complex social and foraging behaviours. Direct underwater observations of wild dolphin feeding behaviour however are rare. At mass spawning aggregations of giant cuttlefish (Sepia apama in the Upper Spencer Gulf in South Australia, a wild female Indo-Pacific bottlenose dolphin (Tursiops aduncus was observed and recorded repeatedly catching, killing and preparing cuttlefish for consumption using a specific and ordered sequence of behaviours. Cuttlefish were herded to a sand substrate, pinned to the seafloor, killed by downward thrust, raised mid-water and beaten by the dolphin with its snout until the ink was released and drained. The deceased cuttlefish was then returned to the seafloor, inverted and forced along the sand substrate in order to strip the thin dorsal layer of skin off the mantle, thus releasing the buoyant calcareous cuttlebone. This stepped behavioural sequence significantly improves prey quality through 1 removal of the ink (with constituent melanin and tyrosine, and 2 the calcareous cuttlebone. Observations of foraging dolphin pods from above-water at this site (including the surfacing of intact clean cuttlebones suggest that some or all of this prey handling sequence may be used widely by dolphins in the region. Aspects of the unique mass spawning aggregations of giant cuttlefish in this region of South Australia may have contributed to the evolution of this behaviour through both high abundances of spawning and weakened post-spawning cuttlefish in a small area (>10,000 animals on several kilometres of narrow rocky reef, as well as potential long-term and regular visitation by dolphin pods to this site.

  4. Retrospective search on biomass harvesting techniques including materials handling and storage

    Energy Technology Data Exchange (ETDEWEB)

    1985-10-01

    This literature search covers the period 1977 to date. The harvesting, materials handling and storage of the following materials: wood; crops and crop residues; peat; sugar cane; reeds, grasses and fers; algae and jojoba shrubs are covered.

  5. Touching Anatomy. : On the Handling of Anatomical Preparations in the Anatomical Cabinets of Frederik Ruysch (1638-1731)

    NARCIS (Netherlands)

    Knoeff, Rina

    2015-01-01

    This paper argues that the anatomical Cabinets of Dutch anatomist Frederik Ruysch must be understood as an early modern workshop in which preparations were continuously handled. It is claimed that preparations actively appealed to anatomists and visitors to handle, re-dissect, touch, and even kiss

  6. Evaluating the Handling Qualities of Flight Control Systems Including Nonlinear Aircraft and System Dynamics

    Science.gov (United States)

    Lin, Raymond Chao

    The handling qualities evaluation of nonlinear aircraft systems is an area of concern in loss-of-control (LOC) prevention. The Get Transfer Function (GetTF) method was demonstrated for evaluating the handling qualities of flight control systems and aircraft containing nonlinearities. NASA's Generic Transport Model (GTM), a nonlinear model of a civilian jet transport aircraft, was evaluated. Using classical techniques, the stability, control, and augmentation (SCAS) systems were designed to control pitch rate, roll rate, and airspeed. Hess's structural pilot model was used to model pilot dynamics in pitch and roll-attitude tracking. The simulated task was simultaneous tracking of, both, pitch and roll attitudes. Eight cases were evaluated: 1) gain increase of pitch-attitude command signal, 2) gain increase of roll-attitude command signal, 3) gain reduction of elevator command signal, 4) backlash in elevator actuator, 5) combination 3 and 4 in elevator actuator, 6) gain reduction of aileron command signal, 7) backlash in aileron actuator, and 8) combination of 6 and 7 in aileron actuator. The GetTF method was used to estimate the transfer function approximating a linear relationship between the proprioceptive signal of the pilot model and the command input. The transfer function was then used to predict the handling qualities ratings (HQR) and pilot-induced oscillation ratings (PIOR). The HQR is based on the Cooper-Harper rating scale. In pitch-attitude tracking, the nominal aircraft is predicted to have Level 2* HQRpitch and 2 control and aircraft systems. A limited human-in-the-loop pitch tracking exercise was also conducted to validate the structural pilot model.

  7. The use of virtual reality for preparation and implementation of JET remote handling operations

    Energy Technology Data Exchange (ETDEWEB)

    Sanders, S. E-mail: ssanders@jet.uk; Rolfe, A.C

    2003-09-01

    The use of real time 3-D computer graphic models for preparation and support of remote handling operations on JET has been in use since the mid 1980s. A complete review has been undertaken of the functional requirements and benefits of VR for remote handling and a subsequent market survey of the present state-of-the-art of VR systems has resulted in the implementation of a new system for JET. The VR system is used in two discrete modes: in on-line mode the remote handling equipment Electro-mechanical hardware is connected to the VR system and provides input for the VR system to update a real time 3-D display of the equipment inside the torus. This mode supplements the video camera system and assists with camera control and warnings of impending or potential collisions. In Off-line mode the operator manipulates the VR system model with no connections to the remote handling equipment. This mode is used during preparation of RH operational strategies, checking of operational feasibility and operations procedures. Various VR systems were evaluated against a detailed technical specification that covered visualisation function and performance, user interface design and base model input/creation capabilities. The cheapest of those systems that satisfied the technical requirements was selected.

  8. Observational trial of safe food handling behavior during food preparation using the example of Campylobacter spp.

    Science.gov (United States)

    Hoelzl, C; Mayerhofer, U; Steininger, M; Brüller, W; Hofstädter, D; Aldrian, U

    2013-03-01

    Campylobacter infections are one of the most prominent worldwide food-related diseases. The primary cause of these infections is reported to be improper food handling, in particular cross-contamination during domestic preparation of raw chicken products. In the present study, food handling behaviors in Austria were surveyed and monitored, with special emphasis on Campylobacter cross-contamination. Forty participants (25 mothers or fathers with at least one child ≤10 years of age and 15 elderly persons ≥60 years of age) were observed during the preparation of a chicken salad (chicken slices plus lettuce, tomato, and cucumber) using a direct structured observational scoring system. The raw chicken carcasses and the vegetable part of the salad were analyzed for Campylobacter. A questionnaire concerning knowledge, attitudes, and interests related to food safety issues was filled out by the participants. Only 57% of formerly identified important hygiene measures were used by the participants. Deficits were found in effective hand washing after contact with raw chicken meat, but proper changing and cleaning of the cutting board was noted. Campylobacter was present in 80% of raw chicken carcasses, albeit the contamination rate was generally lower than the limit of quantification (10 CFU/g). In the vegetable part of the prepared product, no Campylobacter was found. This finding could be due to the rather low Campylobacter contamination rate in the raw materials and the participants' use of some important food handling behaviors to prevent cross-contamination. However, if the initial contamination had been higher, the monitored deficits in safe food handling could lead to quantifiable risks, as indicated in other published studies. The results of the observational trial and the questionnaire indicated knowledge gaps in the food safety sector, suggesting that further education of the population is needed to prevent the onset of foodborne diseases.

  9. Critical control points of complementary food preparation and handling in eastern Nigeria.

    Science.gov (United States)

    Ehiri, J. E.; Azubuike, M. C.; Ubbaonu, C. N.; Anyanwu, E. C.; Ibe, K. M.; Ogbonna, M. O.

    2001-01-01

    OBJECTIVE: To investigate microbial contamination and critical control points (CCPs) in the preparation and handling of complementary foods in 120 households in Imo state, Nigeria. METHODS: The Hazard Analysis Critical Control Point (HACCP) approach was used to investigate processes and procedures that contributed to microbial contamination, growth and survival, and to identify points where controls could be applied to prevent or eliminate these microbiological hazards or reduce them to acceptable levels. Food samples were collected and tested microbiologically at different stages of preparation and handling. FINDINGS: During cooking, all foods attained temperatures capable of destroying vegetative forms of food-borne pathogens. However, the risk of contamination increased by storage of food at ambient temperature, by using insufficiently high temperatures to reheat the food, and by adding contaminated ingredients such as dried ground crayfish and soybean powder at stages where no further heat treatment was applied. The purchasing of contaminated raw foodstuffs and ingredients, particularly raw akamu, from vendors in open markets is also a CCP. CONCLUSION: Although an unsafe environment poses many hazards for children's food, the hygienic quality of prepared food can be assured if basic food safety principles are observed. When many factors contribute to food contamination, identification of CCPs becomes particularly important and can facilitate appropriate targeting of resources and prevention efforts. PMID:11417038

  10. Moving and handling Helen Leslie Moving and handling and Rob MacKenzie Dementia Services Development Centre, University of Stirling £10 including p&p.

    Science.gov (United States)

    2003-09-01

    This book provides guidance on how to approach people with dementia to ensure that moving and handling are positive experiences for both the person with dementia and staff. Simple exercises are provided so the guide can be used for self- study or small group training. Tel: 01786 467740. www.stir.ac.uk /dsdc.

  11. Survey and conceptual flow sheets for coal conversion plant handling-preparation and ash/slag removal operations

    Energy Technology Data Exchange (ETDEWEB)

    Zapp, F.C.; Thomas, O.W.; Silverman, M.D.; Dyslin, D.A.; Holmes, J.M.

    1980-03-01

    This study was undertaken at the request of the Fossil Fuel Processing Division of the Department of Energy. The report includes a compilation of conceptual flow sheets, including major equipment lists, and the results of an availability survey of potential suppliers of equipment associated with the coal and ash/slag operations that will be required by future large coal conversion plant complexes. Conversion plant flow sheet operations and related equipment requirements were based on two representative bituminous coals - Pittsburgh and Kentucky No. 9 - and on nine coal conversion processes. It appears that almost all coal handling and preparation and ash/slag removal equipment covered by this survey, with the exception of some coal comminution equipment, either is on hand or can readily be fabricated to meet coal conversion plant capacity requirements of up to 50,000 short tons per day. Equipment capable of handling even larger capacities can be developed. This approach appears to be unjustified, however, because in many cases a reasonable or optimum number of trains of equipment must be considered when designing a conversion plant complex. The actual number of trains of equipment selected will be influenced by the total requied capacity of the complex, the minimum on-line capacity that can be tolerated in case of equipment failure, reliability of specific equipment types, and the number of reactors and related feed injection stations needed for the specific conversion process.

  12. Assessment of nanoparticle exposure in nanosilica handling process: including characteristics of nanoparticles leaking from a vacuum cleaner.

    Science.gov (United States)

    Kim, Boowook; Kim, Hyunwook; Yu, Il Je

    2014-01-01

    Nanosilica is one of the most widely used nanomaterials across the world. However, their assessment data on the occupational exposure to nanoparticles is insufficient. The present study performed an exposure monitoring in workplace environments where synthetic powders are prepared using fumed nanosilica. Furthermore, after it was observed during exposure monitoring that nanoparticles were emitted through leakage in a vacuum cleaner (even with a HEPA-filter installed in it), the properties of the leaked nanoparticles were also investigated. Workers were exposed to high-concentration nanosilica emitted into the air while pouring it into a container or transferring the container. The use of a vacuum cleaner with a leak (caused by an inadequate sealing) was found to be the origin of nanosilica dispersion in the indoor air. While the particle size of the nanosilica that emitted into the air (during the handling of nanosilica by a worker) was mostly over 100 nm or several microns (µm) due to the coagulation of particles, the size of nanosilica that leaked out of vacuum cleaner was almost similar to the primary size (mode diameter 11.5 nm). Analysis of area samples resulted in 20% (60% in terms of peak concentration) less than the analysis of the personals sample.

  13. Powder Handling Device for X-ray Diffraction Analysis with Minimal Sample Preparation Project

    Data.gov (United States)

    National Aeronautics and Space Administration — This project consists in developing a Vibrating Powder Handling System for planetary X-Ray Diffraction instruments. The principle of this novel sample handling...

  14. Preparing to Receive and Handle Martian Samples When They Arrive on Earth

    Science.gov (United States)

    McCubbin, Francis M.

    2017-01-01

    The Astromaterials Acquisition and Curation Office at NASA Johnson Space Center (JSC) is responsible for curating all of NASA's extraterrestrial samples. Under the governing document, NASA Policy Directive (NPD) 7100.10F+ derivative NPR 'Curation of Extraterrestrial Materials', JSC is charged with 'The curation of all extraterrestrial material under NASA control, including future NASA missions. 'The Directive goes on to define Curation as including'...documentation, preservation, preparation, and distribution of samples for research, education, and public outreach."

  15. Powder Handling Device for X-ray Diffraction Analysis with Minimal Sample Preparation Project

    Data.gov (United States)

    National Aeronautics and Space Administration — This project consists of developing a Vibrating Sample Holder (VSH) for planetary X-Ray Diffraction (XRD) instruments. The principle of this novel sample handling...

  16. Oxidative Stress Induced in Nurses by Exposure to Preparation and Handling of Antineoplastic Drugs in Mexican Hospitals: A Multicentric Study

    Science.gov (United States)

    Gómez-Oliván, Leobardo Manuel; Miranda-Mendoza, Gerardo Daniel; Cabrera-Galeana, Paula Anel; Galar-Martínez, Marcela; Islas-Flores, Hariz; SanJuan-Reyes, Nely; Neri-Cruz, Nadia; García-Medina, Sandra

    2014-01-01

    The impact of involuntary exposure to antineoplastic drugs (AD) was studied in a group of nurses in diverse hospitals in Mexico. The results were compared with a group of unexposed nurses. Anthropometric characteristics and the biochemical analysis were analyzed in both groups. Also, lipid peroxidation level (LPX), protein carbonyl content (PCC), and activity of the antioxidant enzymes superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GPx) were evaluated in blood of study participants as oxidative stress (OS) biomarkers. The group of occupationally exposed (OE) nurses consisted of 30 individuals ranging in age from 25 to 35 years. The control group included 30 nurses who were not occupationally exposed to the preparation and handling of AD and whose anthropometric and biochemical characteristics were similar to those of the OE group. All biomarkers evaluated were significantly increased (P < 0.5) in OE nurses compared to the control group. Results show that the assessment of OS biomarkers is advisable in order to evaluate exposure to AD in nurses. PMID:24719678

  17. Oxidative Stress Induced in Nurses by Exposure to Preparation and Handling of Antineoplastic Drugs in Mexican Hospitals: A Multicentric Study

    Directory of Open Access Journals (Sweden)

    Leobardo Manuel Gómez-Oliván

    2014-01-01

    Full Text Available The impact of involuntary exposure to antineoplastic drugs (AD was studied in a group of nurses in diverse hospitals in Mexico. The results were compared with a group of unexposed nurses. Anthropometric characteristics and the biochemical analysis were analyzed in both groups. Also, lipid peroxidation level (LPX, protein carbonyl content (PCC, and activity of the antioxidant enzymes superoxide dismutase (SOD, catalase (CAT, and glutathione peroxidase (GPx were evaluated in blood of study participants as oxidative stress (OS biomarkers. The group of occupationally exposed (OE nurses consisted of 30 individuals ranging in age from 25 to 35 years. The control group included 30 nurses who were not occupationally exposed to the preparation and handling of AD and whose anthropometric and biochemical characteristics were similar to those of the OE group. All biomarkers evaluated were significantly increased (P<0.5 in OE nurses compared to the control group. Results show that the assessment of OS biomarkers is advisable in order to evaluate exposure to AD in nurses.

  18. Advanced fluidic handling and use of two-phase flow for high throughput structural investigation of proteins on a microfluidic sample preparation platform

    DEFF Research Database (Denmark)

    Lafleur, Josiane P.; Snakenborg, Detlef; Møller, M.

    2010-01-01

    Research on the structure of proteins can bring forth a wealth of information about biological function and can be used to better understand the processes in living cells. This paper reports a new microfluidic sample preparation system for the structural investigation of proteins by Small Angle X......-ray Scattering (SAXS). The system includes hardware and software features for precise fluidic control, synchrotron beamline control, UV absorbance measurements and automated data analysis. The precise fluidic handling capabilities are used to transport and precisely position samples as small as 500 n...

  19. Materials problems in fluidized-bed combustion systems. Appendix 2. Test specimen preparation, handling, and posttest evaluation. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Rogers, E.A.; Holder, J.C.; Minchener, A.J.; Page, A.J.; La Nauze, R.D.

    1980-05-01

    Appendix 2 presents the metallographic data compiled by the National Coal Board, Coal Research Establishment, on materials tested for the Electric Power Research Institute Contract R P 388-1 with Combustion Systems Ltd., UK. Two 1000 h tests were carried out to investigate the corrosion performance of boiler and gas turbine alloys exposed in and above a fluidised bed coal combustor. Details are given of the preparation, handling, and examination procedures. Results of metallographic examination and chemical analyses on the samples examined by CRE are provided. This appendix does not attempt to draw any conclusions from the data: such conclusions appear in the main report. Description of the tests and plant performance data are given in Appendix 1 of this report.

  20. Standardized Competencies for Parenteral Nutrition Order Review and Parenteral Nutrition Preparation, Including Compounding: The ASPEN Model.

    Science.gov (United States)

    Boullata, Joseph I; Holcombe, Beverly; Sacks, Gordon; Gervasio, Jane; Adams, Stephen C; Christensen, Michael; Durfee, Sharon; Ayers, Phil; Marshall, Neil; Guenter, Peggi

    2016-08-01

    Parenteral nutrition (PN) is a high-alert medication with a complex drug use process. Key steps in the process include the review of each PN prescription followed by the preparation of the formulation. The preparation step includes compounding the PN or activating a standardized commercially available PN product. The verification and review, as well as preparation of this complex therapy, require competency that may be determined by using a standardized process for pharmacists and for pharmacy technicians involved with PN. An American Society for Parenteral and Enteral Nutrition (ASPEN) standardized model for PN order review and PN preparation competencies is proposed based on a competency framework, the ASPEN-published interdisciplinary core competencies, safe practice recommendations, and clinical guidelines, and is intended for institutions and agencies to use with their staff.

  1. Home Use Devices: How to Prepare for and Handle Power Outages for Medical Devices That Require Electricity

    Science.gov (United States)

    ... Handle Power Outages for Medical Devices that Require Electricity Center for De CDRH vices and Rad lth ... Handle Power Outages for Medical Devices that Require Electricity As a home medical device user, it is ...

  2. The ortho backbone amide linker (o-BAL) is an easily prepared and highly acid-labile handle for solid-phase synthesis

    DEFF Research Database (Denmark)

    Boas, Ulrik; Brask, Jesper; Christensen, J.B.;

    2002-01-01

    The tris(alkoxy)benzyl backbone amide linker (BAL) has found widespread application in solid-phase synthesis. The key intermediate for preparation of para BAL (p-BAL) is 2,6-dimethoxy-4-hydroxybenzaldehyde; several reports on its synthesis have appeared. However, the ortho analogue of the handle (o...

  3. Requirements for the register of physical persons for the preparation, use and handling radioactive sources; Requisitos para o registro de pessoas fisicas para o preparo, uso e manuseio de fontes radioativas

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-07-15

    This norm establishes the process for register of superior level profession nals enabled to the preparation, using, and handling of radioactive sources. This norm applies to the physical persons candidates applying to the register for preparation, use and handling of radioactive sources in radioactive installations at the industry, agriculture, teaching and researching.

  4. Suggested protocol for collecting, handling and preparing peat cores and peat samples for physical, chemical, mineralogical and isotopic analyses.

    Science.gov (United States)

    Givelet, Nicolas; Le Roux, Gaël; Cheburkin, Andriy; Chen, Bin; Frank, Jutta; Goodsite, Michael E; Kempter, Heike; Krachler, Michael; Noernberg, Tommy; Rausch, Nicole; Rheinberger, Stefan; Roos-Barraclough, Fiona; Sapkota, Atindra; Scholz, Christian; Shotyk, William

    2004-05-01

    For detailed reconstructions of atmospheric metal deposition using peat cores from bogs, a comprehensive protocol for working with peat cores is proposed. The first step is to locate and determine suitable sampling sites in accordance with the principal goal of the study, the period of time of interest and the precision required. Using the state of the art procedures and field equipment, peat cores are collected in such a way as to provide high quality records for paleoenvironmental study. Pertinent field observations gathered during the fieldwork are recorded in a field report. Cores are kept frozen at -18 degree C until they can be prepared in the laboratory. Frozen peat cores are precisely cut into 1 cm slices using a stainless steel band saw with stainless steel blades. The outside edges of each slice are removed using a titanium knife to avoid any possible contamination which might have occurred during the sampling and handling stage. Each slice is split, with one-half kept frozen for future studies (archived), and the other half further subdivided for physical, chemical, and mineralogical analyses. Physical parameters such as ash and water contents, the bulk density and the degree of decomposition of the peat are determined using established methods. A subsample is dried overnight at 105 degree C in a drying oven and milled in a centrifugal mill with titanium sieve. Prior to any expensive and time consuming chemical procedures and analyses, the resulting powdered samples, after manual homogenisation, are measured for more than twenty-two major and trace elements using non-destructive X-Ray fluorescence (XRF) methods. This approach provides lots of valuable geochemical data which documents the natural geochemical processes which occur in the peat profiles and their possible effect on the trace metal profiles. The development, evaluation and use of peat cores from bogs as archives of high-resolution records of atmospheric deposition of mineral dust and trace

  5. Availability assessment and risk assessment regarding handling and preparation of biomass in combustion plants; Tillgaenglighets- och riskbedoemning av system foer hantering och beredning av biobraensle i foerbraenningsanlaeggningar

    Energy Technology Data Exchange (ETDEWEB)

    Biguen, Helen; Bodlund, Gunnar; Dahlloef, Lars; Pettersson, Lars [SwedPower, Stockholm (Sweden)

    2005-04-01

    or explosion as well as critical functions are identified with FMEA technique. At the same time fault frequency and fault probability for the events included in fault tree are estimated. The events are for example presence of combustible material, ignition source, functioning fire sprinklers. The fault trees are modeled in a commercially accessible calculation program. The evaluation shows that the frequency for 'fire or explosion' is about 3 times/year. A study was done to evaluate the parameters that can contribute to reduce risk from other risk mitigating functions. Our conclusion is that both the systematic availability analyses and the probabilistic risk analyses have potential, correct applied, to be the tools to support decisions in a planning phase. Both during design of new plant or refurbishment of old plants. At the same time analysis shows that simplified analysis with rough but relevant input give significant answers to the questions. The models of analyses prepared during a project period should be alive during the continuous operation. Faults and disturbances in the plant should be continuously analysed and thus influence availability and fault data for individual components and functions. This might be done when working orders are reported, without increasing the burden of paper work on the operating organization. The support for decision given by the analyses is valuable when refurbish proposals are evaluated and may give answers to the question if the plant fulfill future legislation and regulations.

  6. 43 CFR 404.50 - What information will be included in the feasibility report prepared by Reclamation.

    Science.gov (United States)

    2010-10-01

    ... PROGRAM Feasibility Studies § 404.50 What information will be included in the feasibility report prepared... will be based on Reclamation's review of the feasibility study and its application of the criteria set... feasibility report prepared by Reclamation. 404.50 Section 404.50 Public Lands: Interior Regulations...

  7. AG-NGS: a powerful and user-friendly computing application for the semi-automated preparation of next-generation sequencing libraries using open liquid handling platforms.

    Science.gov (United States)

    Callejas, Sergio; Álvarez, Rebeca; Benguria, Alberto; Dopazo, Ana

    2014-01-01

    Next-generation sequencing (NGS) is becoming one of the most widely used technologies in the field of genomics. Library preparation is one of the most critical, hands-on, and time-consuming steps in the NGS workflow. Each library must be prepared in an independent well, increasing the number of hours required for a sequencing run and the risk of human-introduced error. Automation of library preparation is the best option to avoid these problems. With this in mind, we have developed automatic genomics NGS (AG-NGS), a computing application that allows an open liquid handling platform to be transformed into a library preparation station without losing the potential of an open platform. Implementation of AG-NGS does not require programming experience, and the application has also been designed to minimize implementation costs. Automated library preparation with AG-NGS generated high-quality libraries from different samples, demonstrating its efficiency, and all quality control parameters fell within the range of optimal values.

  8. Kollektiv Handling

    DEFF Research Database (Denmark)

    Toubøl, Jonas

    2012-01-01

    Boganmeldelse af Flemming Ibsen, Laust Høgedahl & Steen Sheuer: Kollektiv Handling. Faglig organisering og skift af fagforening. Nyt fra Samfundsvidenskaberne, Frederiksberg, 2012.......Boganmeldelse af Flemming Ibsen, Laust Høgedahl & Steen Sheuer: Kollektiv Handling. Faglig organisering og skift af fagforening. Nyt fra Samfundsvidenskaberne, Frederiksberg, 2012....

  9. Solar cells, structures including organometallic halide perovskite monocrystalline films, and methods of preparation thereof

    KAUST Repository

    Bakr, Osman M.

    2017-03-02

    Embodiments of the present disclosure provide for solar cells including an organometallic halide perovskite monocrystalline film (see fig. 1.1B), other devices including the organometallic halide perovskite monocrystalline film, methods of making organometallic halide perovskite monocrystalline film, and the like.

  10. Evaluation of sustained release suppositories prepared with fatty base including solid fats with high melting points.

    Science.gov (United States)

    Takatori, Toshihito; Shimono, Norihito; Higaki, Kazutaka; Kimura, Toshikiro

    2004-07-08

    To prepare the sustained release suppositories, solid fats such as polyglycerol ester of fatty acids (PGEFs) or beeswax were utilized with a fatty suppository base, Witepsol H15. PGEFs such as decaglycerol heptabehenate (HB750) and hexaglycerol pentastearate (PS500), and beeswax have relatively high melting points. The addition of PGEFs or beeswax to Witepsol H15 increased the apparent viscosity of suppository bases at 37 degrees C without any large change in the melting point of Witepsol H15. Moreover, the apparent viscosity of a mixed base with HB750, PS500 or beeswax at 37 degrees C was significantly correlated with the amount of each solid fat in a mixed base. The release of acetaminophen (AAP), a model drug, from suppositories was delayed by HB750, PS500 or beeswax, and an excellent correlation was observed between the apparent viscosity of these mixed bases and Higuchi's rate constants in each mixed base suppository, suggesting that these solid fats could regulate the drug release from the mixed base suppositories by changing their viscosity. In the in vivo absorption study in rats, several suppositories made from Witepsol H15-HB750 or Witepsol H15-beeswax mixed bases prolonged the rectal absorption of AAP without reducing AUC. In conclusion, by using solid fats such as HB750 and beeswax with relatively high melting points, it is possible to control the rate of drug release from fatty base suppositories for maintaining the plasma concentration of drugs for longer time periods.

  11. The role of natural gas as a primary fuel in the near future, including comparisons of acquisition, transmission and waste handling costs of as with competitive alternatives.

    Science.gov (United States)

    Liang, Fang-Yu; Ryvak, Marta; Sayeed, Sara; Zhao, Nick

    2012-04-23

    Natural gas comprises about a quarter of the United States' energy use. It is more environmentally friendly than oil and coal due to lower carbon dioxide (CO2) emissions per unit, less costly per unit of energy and more readily available domestically in abundant supply. However, due to a number of barriers in the political, infrastructural, pricing and other arenas, the use of natural gas as a significant energy source in the United States has been limited. In our paper, we highlight the favorable qualities of natural gas and its benefits for the consumer, producer, and environment, having compared the costs of the various components of the natural gas business such as drilling and transport to that of coal and oil. Moreover, we touch upon the major issues that have prevented a more prevalent use of the gas, such as the fact that the infrastructure of natural gas is more costly since it is transported though pipelines whereas other energy sources such as oil and coal have flexible systems that use trains, trucks and ships. In addition, the powerful lobbies of the coal and oil businesses, along with the inertia in the congress to pass a national climate change bill further dampens incentives for these industries to invest in natural gas, despite its various attractive qualities. We also include discussions of policy proposals to incentive greater use of natural gas in the future.

  12. Preparation

    Directory of Open Access Journals (Sweden)

    M.M. Dardir

    2014-03-01

    Full Text Available Some hexanamide-mono and di-linoleniate esters were prepared by the reaction of linolenic acid and hexanamide (derived from the reaction of hexanoic acid and diethanolamine. The chemical structure for the newly prepared hexanamide-mono and di-linoleniate esters were elucidated using elemental analysis, (FTIR, H 1NMR and chemical ionization mass spectra (CI/Ms spectroscopic techniques. The results of the spectroscopic analysis indicated that they were prepared through the right method and they have high purity. The new prepared esters have high biodegradability and lower toxicity (environmentally friendly so they were evaluated as a synthetic-based mud (ester-based mud for oil-well drilling fluids. The evaluation included study of the rheological properties, filtration and thermal properties of the ester based-muds formulated with the newly prepared esters compared to the reference commercial synthetic-based mud.

  13. Handling Metalloproteinases.

    Science.gov (United States)

    Fridrich, Sven; Karmilin, Konstantin; Stöcker, Walter

    2016-02-02

    Substrate cleavage by metalloproteinases involves nucleophilic attack on the scissile peptide bond by a water molecule that is polarized by a catalytic metal, usually a zinc ion, and a general base, usually the carboxyl group of a glutamic acid side chain. The zinc ion is most often complexed by imidazole nitrogens of histidine side chains. This arrangement suggests that the physiological pH optimum of most metalloproteinases is in the neutral range. In addition to their catalytic metal ion, many metalloproteinases contain additional transition metal or alkaline earth ions, which are structurally important or modulate the catalytic activity. As a consequence, these enzymes are generally sensitive to metal chelators. Moreover, the catalytic metal can be displaced by adventitious metal ions from buffers or biological fluids, which may fundamentally alter the catalytic function. Therefore, handling, purification, and assaying of metalloproteinases require specific precautions to warrant their stability. Copyright © 2016 John Wiley & Sons, Inc.

  14. Handling Culture

    NARCIS (Netherlands)

    Pieter van Nispen tot Pannerden

    2011-01-01

    The article indicates how companies may prepare for and deal with cultural differences. Because the research base is still rather limited an overall perspective may not be realised. After discussing definitions and concepts of culture, as well as values, cultural differences between states are discu

  15. Handling Culture

    NARCIS (Netherlands)

    Nispen tot Pannerden, P.J.M. van

    2011-01-01

    The article indicates how companies may prepare for and deal with cultural differences. Because the research base is still rather limited an overall perspective may not be realised. After discussing definitions and concepts of culture, as well as values, cultural differences between states are discu

  16. The Type of Forage Substrate Preparation Included as Substrate in a RUSITEC System Affects the Ruminal Microbiota and Fermentation Characteristics

    Directory of Open Access Journals (Sweden)

    Alexandre V. Chaves

    2017-04-01

    Full Text Available In vitro fermentation systems such as the rumen simulation technique (RUSITEC are frequently used to assess dietary manipulations in livestock, thereby limiting the use of live animals. Despite being in use for nearly 40 years, improvements are continually sought in these systems to better reflect and mimic natural processes in ruminants. The aim of this study was to evaluate the effect of forage preparation, i.e., frozen minced (FM and freeze-dried and ground (FDG, on the ruminal microbiota and on fermentation characteristics when included as a substrate in a RUSITEC system. A completely randomized design experiment was performed over a 15-day period, with 7 days of adaptation and an 8-day experimental period. Fermentation parameters (total gas, CH4, and volatile fatty acid production were analyzed on a daily basis over the experimental period and the archaeal and bacterial microbiota (liquid-associated microbes [LAM] and solid-associated microbes [SAM] was assessed at 0, 5, 10, and 15 days using high-throughput sequencing of the 16S rRNA gene. Results from this study suggested a tendency (P = 0.09 of FM treatment to increase daily CH4 (mg/d production by 16.7% when compared with FDG treatment. Of the major volatile fatty acids (acetate, propionate, and butyrate, only butyrate production was greater (P = 0.01 with FM treatment compared with FDG substrate. The archaeal and bacterial diversity and richness did not differ between the forage preparations, although feed particle size of the forage had a significant effect on microbial community structure in the SAM and LAM samples. The Bacteroidetes phylum was more relatively abundant in the FM substrate treatment, while Proteobacteria was enriched in the FDG treatment. At the genus-level, Butyrivibrio, Prevotella, and Roseburia were enriched in the FM substrate treatment and Campylobacter and Lactobacillus in the FDG substrate treatment. Evidence from this study suggests that forage preparation

  17. Improving coal handling effectiveness

    Energy Technology Data Exchange (ETDEWEB)

    Walker, S.

    2003-10-01

    Appropriate coal handling systems are essential for successful coal utilisation. The paper looks at some of the options available, including crushers and hammer mills, wear-resistant liners for chutes and wagons, and dewatering systems. These are individual components within larger systems such as stockyard stacking and reclaiming installations. 5 photos.

  18. New transport and handling contract

    CERN Multimedia

    SC Department

    2008-01-01

    A new transport and handling contract entered into force on 1.10.2008. As with the previous contract, the user interface is the internal transport/handling request form on EDH: https://edh.cern.ch/Document/TransportRequest/ To ensure that you receive the best possible service, we invite you to complete the various fields as accurately as possible and to include a mobile telephone number on which we can reach you. You can follow the progress of your request (schedule, completion) in the EDH request routing information. We remind you that the following deadlines apply: 48 hours for the transport of heavy goods (up to 8 tonnes) or simple handling operations 5 working days for crane operations, transport of extra-heavy goods, complex handling operations and combined transport and handling operations in the tunnel. For all enquiries, the number to contact remains unchanged: 72202. Heavy Handling Section TS-HE-HH 72672 - 160319

  19. Availability assessment and risk assessment regarding handling and preparation of biomass in combustion plants; Tillgaenglighets- och riskbedoemning av system foer hantering och beredning av biobraensle i foerbraenningsanlaeggningar

    Energy Technology Data Exchange (ETDEWEB)

    Biguen, Helen; Bodlund, Gunnar; Dahlloef, Lars; Pettersson, Lars [SwedPower, Stockholm (Sweden)

    2005-04-01

    In the design of new, or refurbishment of old, bio-fuel fired plants, the design of the fuel-handling systems is often based on experiences from existing plants. The size of the bio-fuel storage is decided from fuel consumption during a long holiday with no transports, and available storage area on the site. Auxiliary capacities and redundancies in the bio-fuel handling systems are often determined by investment costs rather than by life-cycle costs. Risk analyses are realized according to Swedish legislation for Occupation and Health and its regulations for work in environment with risk of explosion. The plant is designed to minimize the risk for explosion and also to minimize the consequences of an explosion. The plant is provided with fire protection functions according to applicable legislations and regulations. Safety functions can either be passive as physical separations or active as different kinds of detecting and consequence reducing systems. The aim of this report is to emphasize the use of quantitative tools for analysis to evaluate alternative system designs from the viewpoint of availability and risk. The availability analysis gives the opportunity to quantitatively analyse suggested alternative solutions of a system and to study the influence of redundant system functions, storage volumes etceteras. The analysis also gives the opportunity to evaluate effects on manning, work on three shifts or daytime with extra duty on call, as well as the optimization of spare parts toward delivery times and agreements for service. The probabilistic risk analysis gives opportunities to place in order of precedence and quantitatively evaluate the effect on total risk from suggested passive protective measures and different types of active protection functions such as fire sprinkling. The methods of analysis are above all an aid and support to optimize system design and life cycle cost during the design phase. During continuous operation the quantitative analyses are

  20. CANISTER HANDLING FACILITY WORKER DOSE ASSESSMENT

    Energy Technology Data Exchange (ETDEWEB)

    D.T. Dexheimer

    2004-02-27

    The purpose of this calculation is to estimate radiation doses received by personnel working in the Canister Handling Facility (CHF) performing operations to receive transportation casks, transfer wastes, prepare waste packages, perform associated equipment maintenance. The specific scope of work contained in this calculation covers individual worker group doses on an annual basis, and includes the contributions due to external and internal radiation. The results of this calculation will be used to support the design of the CHF and provide occupational dose estimates for the License Application.

  1. Atomic force microscopy for the study of specially prepared surfaces including transferred Langmuir-Blodgett layers. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Dr. J. D. Miller

    1999-06-02

    During the past four years a major number of surface science research programs in the Department of Metallurgical Engineering at the University of Utah have involved the use of the Atomic Force Microscope (AFM) and the Langmuir-Blodgett (LB) film balance procured with financial assistance from DOE under grant number DE-FG03-96ER76049. These instruments have been used for research in the areas of nonsulfide flotation chemistry, mineral processing, waste paper deinking, water treatment, treatment of contaminated soil, coal preparation, and plastics recycling. In addition, the AFM and LB film balance have been of great help to university researchers in other departments at the University of Utah and elsewhere, as well as researchers from industry.

  2. Solidex 84 - modern technology in bulk solids handling

    Energy Technology Data Exchange (ETDEWEB)

    1984-01-01

    Proceedings from Conference on solids handling. Sections which are of interest include coal and ash handling, and flow problems and explosion hazards in bulk handling plant. 14 papers have been abstracted separately.

  3. Development of the preparation technology of macroporous sorbent for industrial off-gas treatment including {sup 14}C

    Energy Technology Data Exchange (ETDEWEB)

    Cho, Il Hoon; Cho, Young Hyun; Park, Guen Il; Kim, In Tae; Kim, June Hyung; Ahn, Byung Kil

    2001-01-01

    For environmental and health effects due to increasing levels of pollution in the atmosphere, it is necessary to develop environmentally sound technologies for the treatment of greenhouse gases (CO{sub 2}, CH{sub 4}, CFC, etc.) and acid gases (SOx, NOx, etc.). Specifically, advanced technology for CO{sub 2} capturing is currently one of the most important environmental issues in worldwide. {sup 14}CO{sub 2}, specially which has been gradually emerging issue in the nuclear facilities, is generated about 330 ppm from the CANDU (Canadian Deuterium Uranium Reactor) nuclear power plant and the DUPIC (Direct Use of spent PWR fuel in CANDU reactors) process which is the process of spent fuel treatment. For this purpose, it is necessary to develop the most efficient treatment technology of CO{sub 2} capture by various lime materials in semi- or dry process, it should be also considering a removal performance, waste recycling and safety of disposal. In order to develop a highly active slaked lime as a sorbent for CO{sub 2} and high temperature desulfurization, macroporous slaked lime is necessarily prepared by modified swelling process and equipment, which was developed under carrying out this project. And also for the optimal removal process of off-gases the removal performance tests of various sorbents and the effects of relative humidity and bed depth on the removal capacity must be considered.

  4. WIPP Remote Handled Waste Facility: Performance Dry Run Operations

    Energy Technology Data Exchange (ETDEWEB)

    Burrington, T. P.; Britain, R. M.; Cassingham, S. T.

    2003-02-24

    The Remote Handled (RH) TRU Waste Handling Facility at the Waste Isolation Pilot Plant (WIPP) was recently upgraded and modified in preparation for handling and disposal of RH Transuranic (TRU) waste. This modification will allow processing of RH-TRU waste arriving at the WIPP site in two different types of shielded road casks, the RH-TRU 72B and the CNS 10-160B. Washington TRU Solutions (WTS), the WIPP Management and Operation Contractor (MOC), conducted a performance dry run (PDR), beginning August 19, 2002 and successfully completed it on August 24, 2002. The PDR demonstrated that the RHTRU waste handling system works as designed and demonstrated the handling process for each cask, including underground disposal. The purpose of the PDR was to develop and implement a plan that would define in general terms how the WIPP RH-TRU waste handling process would be conducted and evaluated. The PDR demonstrated WIPP operations and support activities required to dispose of RH-TRU waste in the WIPP underground.

  5. Evaluation of octyl p-methoxycinnamate included in liposomes and cyclodextrins in anti-solar preparations: preparations, characterizations and in vitro penetration studies.

    Science.gov (United States)

    Monteiro, Mariana Sato de Souza de Bustamante; Ozzetti, Rafael Antonio; Vergnanini, André Luiz; de Brito-Gitirana, Lycia; Volpato, Nadia Maria; de Freitas, Zaida Maria Faria; Ricci-Júnior, Eduardo; dos Santos, Elisabete Pereira

    2012-01-01

    Awareness of the harmful effects of ultraviolet radiation has led to the increasing use of sunscreens, thus, the development of safe and effective antisolar preparations is important. The inclusion of sunscreen molecules in different release systems, like liposomes (lipo) and cyclodextrins (CD) is therefore required. The in vivo sun protection factor (SPF), water resistance, and in vitro transdermal penetration test of octyl p-methoxycinnamate (OMC) in different dispersions, such as OMC encapsulated in liposomes (lipo/OMC), OMC encapsulated in β-cyclodextrins (β-CD/OMC), OMC encapsulated in both release systems (lipo/OMC and β-CD/OMC), and an OMC-free formulation were determined. Although the formulation containing only the lipo/OMC system revealed high value of in vivo SPF (11.0 ± 1.3) and water resistance (SPF = 10.3 ± 2.2), the formulation containing both release systems (lipo/OMC + β-cyclodextrin/OMC) showed the best result in the in vivo SPF test (11.6 ± 1.6). In the penetration test, the formulation containing the lipo/OMC system had better performance, since a high amount of OMC in the epidermis (18.04 ± 1.17 μg) and a low amount of OMC in the dermis (9.4 ± 2.36 μg) were observed. These results suggest that liposomes interact with the cells of the stratum corneum, promoting retention of OMC in this layer. According to our study, the lipo/OMC system is the most advantageous release system, due to its ability to both increase the amount of OMC in the epidermis and decrease the risk of percutaneous absorption.

  6. Calcium phosphate composite materials including inorganic powders, BSA or duplex DNA prepared by W/O/W interfacial reaction method

    Energy Technology Data Exchange (ETDEWEB)

    Fujiwara, Masahiro [National Institute of Advanced Industrial Science and Technology (AIST), Kansai Center, 1-8-31 Midorigaoka, Ikeda, Osaka 563-8577 (Japan)], E-mail: m-fujiwara@aist.go.jp; Shiokawa, Kumi; Morigaki, Kenichi; Tatsu, Yoshiro; Nakahara, Yoshiko [National Institute of Advanced Industrial Science and Technology (AIST), Kansai Center, 1-8-31 Midorigaoka, Ikeda, Osaka 563-8577 (Japan)

    2008-03-10

    We reported before that inorganic reaction occurring at the interface of W/O/W emulsion is advantageous to produce hollow spheres (microcapsules) of inorganic matrices such as silica. This process enables us to include various materials into inorganic matrices directly. Calcium phosphates were also produced from NH{sub 4}H{sub 2}PO{sub 4} and Ca(OH){sub 2} by this interfacial reaction method. Various biomaterials are directly incorporated into crystalline calcium phosphate matrices, when the biomaterials are added to the inner water phase of the W/O/W emulsion. ZrO{sub 2} and Al{sub 2}O{sub 3} powders were effectively encapsulated in calcium phosphates such as hydroxyapatite (HAp). The images of backscattered electron of FE-SEM observations indicated that ZrO{sub 2} particles were included in HAp, while they adhered to the surface of HAp in the case of a simple precipitation method. Biomacromolecules such as BSA and duplex DNA were also included in HAp using the inner water phases dissolving them. Fluorescent microscopy observations revealed that biomacromolecules incorporated in HAp localized in some domains of the HAp matrices. Biomacromolecules thus included were scarcely liberated into deionized water, indicating their strong encapsulation in HAp. This general and simple methodology will provide various composite materials of calcium phosphates, which are applicable to regenerative medicine, DDS, GDS and more.

  7. Handling sharps and needles

    Science.gov (United States)

    ... this page: //medlineplus.gov/ency/patientinstructions/000444.htm Handling sharps and needles To use the sharing features ... Health Administration. OSHA fact sheet: protecting yourself when handling contaminated sharps. Updated January 2011. Available at: www. ...

  8. Status of ITER neutral beam cell remote handling system

    Energy Technology Data Exchange (ETDEWEB)

    Sykes, N., E-mail: nick.sykes@ccfe.ac.uk [CCFE. Culham Science Centre, Abingdon OX14 3DB (United Kingdom); Belcher, C. [Oxford Technologies Ltd, Abingdon OX14 1RJ (United Kingdom); Choi, C.-H. [ITER Organisation, CS90 046, 13067 St. Paul les Durance Cedex (France); Crofts, O. [CCFE. Culham Science Centre, Abingdon OX14 3DB (United Kingdom); Crowe, R. [Oxford Technologies Ltd, Abingdon OX14 1RJ (United Kingdom); Damiani, C. [Fusion for Energy, C/Josep Pla 2, Torres Diagonal Litoral-B3, E-08019 Barcelona (Spain); Delavalle, S.; Meredith, L. [Oxford Technologies Ltd, Abingdon OX14 1RJ (United Kingdom); Mindham, T.; Raimbach, J. [CCFE. Culham Science Centre, Abingdon OX14 3DB (United Kingdom); Tesini, A. [ITER Organisation, CS90 046, 13067 St. Paul les Durance Cedex (France); Van Uffelen, M. [Fusion for Energy, C/Josep Pla 2, Torres Diagonal Litoral-B3, E-08019 Barcelona (Spain)

    2013-10-15

    The ITER neutral beam cell will contain up to three heating neutral beams and one diagnostic neutral beam, and four upper ports. Though manual maintenance work is envisaged within the cell, when containment is breached, or the radiological protection is removed the maintenance must be conducted remotely. This maintenance constitutes the removal and replacement of line replaceable units, and their transport to and from a cask docked to the cell. A design of the remote handling system has been prepared to concept level which this paper describes including the development of a beam line transporter, beam source remote handling equipment, upper port remote handling equipment and equipment for the maintenance of the neutral shield. This equipment has been developed complete the planned maintenance tasks for the components of the neutral beam cell and to have inherent flexibility to enable as yet unforeseen tasks and recovery operations to be performed.

  9. Status of ITER neutral beam cell remote handling system

    CERN Document Server

    Sykes, N; Choi, C-H; Crofts, O; Crowe, R; Damiani, C; Delavalle, S; Meredith, L; Mindham, T; Raimbach, J; Tesini, A; Van Uffelen, M

    2013-01-01

    The ITER neutral beam cell will contain up to three heating neutral beams and one diagnostic neutral beam, and four upper ports. Though manual maintenance work is envisaged within the cell, when containment is breached, or the radiological protection is removed the maintenance must be conducted remotely. This maintenance constitutes the removal and replacement of line replaceable units, and their transport to and from a cask docked to the cell. A design of the remote handling system has been prepared to concept level which this paper describes including the development of a beam line transporter, beam source remote handling equipment, upper port remote handling equipment and equipment for the maintenance of the neutral shield. This equipment has been developed complete the planned maintenance tasks for the components of the neutral beam cell and to have inherent flexibility to enable as yet unforeseen tasks and recovery operations to be performed.

  10. Impact of the new handling recommendations for hazardous drugs in a hospital pharmacy service

    Directory of Open Access Journals (Sweden)

    Beatriz G García-Alcántara

    2017-03-01

    Full Text Available Objective: To describe the actions taken by the Pharmacy Unit in a tertiary hospital in order to adapt to the recommendations established by NIOSH 2014 for handling Hazardous Drugs. Method: A retrospective observational study. A list was prepared including all hazardous drugs according to NIOSH 2014 that were available at the hospital as marketed or foreign drugs, or used in clinical trials, and there was a review of the processes of acquisition, repackaging, preparation, circuits, organizational, dispensing and identification. Results: After the analysis, a report including all needs was prepared and sent to the Hospital Management. Any relevant information about the handling and administration of hazardous drugs was included in the prescription computer program. There were changes in the acquisition process of two drugs, in order to avoid splitting and multi-dose formulations. An alternative or improvement was found for 35 253 of the 75 779 units of hazardous drugs repackaged in one year. The Pharmacy Unit took over the preparation of four non-sterile medications, as well as the preparation of all sterile parenteral medications included in Lists 1 and 2 that were not previously prepared there, as well as one from List 3. Information was also included about the preparation processes of Magistral Formulations that involved hazardous drugs from Lists 2 or 3. Conclusion: The adaptation to the recommendations by NIOSH 2014 has represented a change, but also a significant reduction in the handling process of hazardous drugs by the healthcare staff, therefore reducing the risk of occupational exposure.

  11. CANISTER HANDLING FACILITY CRITICALITY SAFETY CALCULATIONS

    Energy Technology Data Exchange (ETDEWEB)

    C.E. Sanders

    2005-04-07

    This design calculation revises and updates the previous criticality evaluation for the canister handling, transfer and staging operations to be performed in the Canister Handling Facility (CHF) documented in BSC [Bechtel SAIC Company] 2004 [DIRS 167614]. The purpose of the calculation is to demonstrate that the handling operations of canisters performed in the CHF meet the nuclear criticality safety design criteria specified in the ''Project Design Criteria (PDC) Document'' (BSC 2004 [DIRS 171599], Section 4.9.2.2), the nuclear facility safety requirement in ''Project Requirements Document'' (Canori and Leitner 2003 [DIRS 166275], p. 4-206), the functional/operational nuclear safety requirement in the ''Project Functional and Operational Requirements'' document (Curry 2004 [DIRS 170557], p. 75), and the functional nuclear criticality safety requirements described in the ''Canister Handling Facility Description Document'' (BSC 2004 [DIRS 168992], Sections 3.1.1.3.4.13 and 3.2.3). Specific scope of work contained in this activity consists of updating the Category 1 and 2 event sequence evaluations as identified in the ''Categorization of Event Sequences for License Application'' (BSC 2004 [DIRS 167268], Section 7). The CHF is limited in throughput capacity to handling sealed U.S. Department of Energy (DOE) spent nuclear fuel (SNF) and high-level radioactive waste (HLW) canisters, defense high-level radioactive waste (DHLW), naval canisters, multicanister overpacks (MCOs), vertical dual-purpose canisters (DPCs), and multipurpose canisters (MPCs) (if and when they become available) (BSC 2004 [DIRS 168992], p. 1-1). It should be noted that the design and safety analyses of the naval canisters are the responsibility of the U.S. Department of the Navy (Naval Nuclear Propulsion Program) and will not be included in this document. In addition, this calculation is valid for

  12. Robust ASPNET Exception Handling

    CERN Document Server

    Dumond, Lee

    2009-01-01

    This Wrox Blox will teach you how to unravel the mysteries of exception handling in ASP.NET.   First, you'll get a thorough introduction to structured exception handling in the .NET Framework, learn about the Exception class, the related C# language constructs, and how exceptions propagate up the call stack. Then, you'll delve into a variety of practical topics such as: when, where, and how to properly throw, catch, and handle exceptions in your code; how to employ "defensive programming" techniques to avoid triggering the most common CLR exceptions; adopting exception handling "best practices

  13. Cargo handling know-how

    Energy Technology Data Exchange (ETDEWEB)

    Bachman, T.; Fischer, M. [Liebherr-Werk Nenzing GmbH (Austria)

    2004-01-01

    The paper reviews recent bulk handling crane orders from Liebherr. These include mobile harbour cranes at the Port of Dunkirk, a four-rope grab crane at Phu My Port, Vietnam and CBG cranes at Balikpapan Coal Terminal, Indonesia. 4 figs.

  14. Preparation and certification of the Polish reference material Virginia Tobacco Leaves (CTA-VTL-2) for inorganic trace analysis including microanalysis

    Energy Technology Data Exchange (ETDEWEB)

    Dybczynski, R.; Polkowska-Motrenko, H.; Samczynski, Z.; Szopa, Z.

    1997-12-31

    A new Polish certified reference material Virginia Tobacco Leaves (CTA-VTL-2) for inorganic trace analysis including microanalysis has been prepared. Certification of the candidate reference material was based on the world-wide interlaboratory comparison in which 60 laboratories from 18 countries, participated using various analytical methods and techniques. Data evaluation performed by means of the new multifunctional software package -SSQC. Recommended values were assigned for 33 and `information` values for 10 elements, respectively. The validity of `certified` values was confirmed for several elements using `very accurate` methods developed in this Laboratory. (author). 47 refs, 28 figs, 12 tabs.

  15. Socialanalyse og handling

    DEFF Research Database (Denmark)

    Henriksen, Kirsten; Alminde, Rikke; Stevnsgaard Andersen, Mona

    Social analyse og handling er et redskab beregnet til at inspirere socialarbejdere til at arbejde analytisk, systematisk samt refleksivt med konkrete problemstillinger i socialt arbejde.......Social analyse og handling er et redskab beregnet til at inspirere socialarbejdere til at arbejde analytisk, systematisk samt refleksivt med konkrete problemstillinger i socialt arbejde....

  16. Practices of Handling

    DEFF Research Database (Denmark)

    Ræbild, Ulla

    area within fashion research. This paper proposes an understanding of the work process of fashion designers as practices of handling comprising a number of embodied methodologies tied to both spatial and temporal dimensions. The term handling encompasses four meanings. As a verb it is literally...... to touch, pick up, carry, or feel with the hands. Figuratively it is to manage, deal with, direct, train, or control. Additionally, as a noun, a handle is something by which we grasp or open up something. Lastly, handle also has a Nordic root, here meaning to trade, bargain or deal. Together all four...... meanings seem to merge in the fashion design process, thus opening up for an embodied engagement with matter that entails direction giving, organizational management and negotiation. By seeing processes of handling as a key fashion methodological practice, it is possible to divert the discourse away from...

  17. CHR -- Character Handling Routines

    Science.gov (United States)

    Charles, A. C.; Rees, P. C. T.; Chipperfield, A. J.; Jenness, T.

    This document describes the Character Handling Routine library, CHR, and its use. The CHR library augments the limited character handling facilities provided by the Fortran 77 standard. It offers a range of character handling facilities: from formatting Fortran data types into text strings and the reverse, to higher level functions such as wild card matching, string sorting, paragraph reformatting and justification. The library may be used simply for building text strings for interactive applications or as a basis for more complex text processing applications.

  18. Helping Kids Handle Worry

    Science.gov (United States)

    ... Child What Kids Say About: Handling Stress Anxiety, Fears, and Phobias Community Service: A Family's Guide to Getting Involved ... With Stress Teens Talk About Stress (Video) Anxiety, Fears, and Phobias Childhood Stress How Can I Help My Child ...

  19. Handling Pyrophoric Reagents

    Energy Technology Data Exchange (ETDEWEB)

    Alnajjar, Mikhail S.; Haynie, Todd O.

    2009-08-14

    Pyrophoric reagents are extremely hazardous. Special handling techniques are required to prevent contact with air and the resulting fire. This document provides several methods for working with pyrophoric reagents outside of an inert atmosphere.

  20. 7 CFR 915.10 - Handle.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 8 2010-01-01 2010-01-01 false Handle. 915.10 Section 915.10 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements and... prepared for market. In the event a grower sells his avocados to a handler who is not so registered...

  1. Hearing children's voices? Including children's perspectives on their experiences of domestic violence in welfare reports prepared for the English courts in private family law proceedings.

    Science.gov (United States)

    Macdonald, Gillian S

    2017-03-01

    This research examined Children and Family Court Advisory and Support Service (Cafcass) reports prepared for private family court proceedings in domestic violence cases in England. The research found that in cases where children's accounts identified them as victims of violence, these disclosures regularly disappeared from report recommendations. Particular discourses regarding 'child welfare' and 'contact' were identified, which routinely impacted on the ways in which children's voices were taken into account. Whilst culturally there has undoubtedly been an influential move towards including children's perspectives in decision-making that affects them, how these views are interpreted and represented is subject to adult 'gate-keeping' and powerful cultural and professional ideologies regarding 'child welfare' and 'post-separation family relationships'. This research found that the unrelenting influence of deeply embedded beliefs regarding the preservation or promotion of relationships with fathers continues to have the effect of marginalising issues of safeguarding, including children's voiced experiences of violence, in all but the most exceptional of cases. Rather, safeguarding concerns in respect of domestic violence and child abuse were persistently overshadowed by a dominant presumption of the overall benefits of contact with fathers. Crown Copyright © 2017. Published by Elsevier Ltd. All rights reserved.

  2. TRANSPORT/HANDLING REQUESTS

    CERN Multimedia

    Groupe ST/HM

    2002-01-01

    A new EDH document entitled 'Transport/Handling Request' will be in operation as of Monday, 11th February 2002, when the corresponding icon will be accessible from the EDH desktop, together with the application instructions. This EDH form will replace the paper-format transport/handling request form for all activities involving the transport of equipment and materials. However, the paper form will still be used for all vehicle-hire requests. The introduction of the EDH transport/handling request form is accompanied by the establishment of the following time limits for the various services concerned: 24 hours for the removal of office items, 48 hours for the transport of heavy items (of up to 6 metric tons and of standard road width), 5 working days for a crane operation, extra-heavy transport operation or complete removal, 5 working days for all transport operations relating to LHC installation. ST/HM Group, Logistics Section Tel: 72672 - 72202

  3. Project Execution Plan for the Remote Handled Low-Level Waste Disposal Project

    Energy Technology Data Exchange (ETDEWEB)

    Danny Anderson

    2014-07-01

    As part of ongoing cleanup activities at the Idaho National Laboratory (INL), closure of the Radioactive Waste Management Complex (RWMC) is proceeding under the Comprehensive Environmental Response, Compensation, and Liability Act (42 USC 9601 et seq. 1980). INL-generated radioactive waste has been disposed of at RWMC since 1952. The Subsurface Disposal Area (SDA) at RWMC accepted the bulk of INL’s contact and remote-handled low-level waste (LLW) for disposal. Disposal of contact-handled LLW and remote-handled LLW ion-exchange resins from the Advanced Test Reactor in the open pit of the SDA ceased September 30, 2008. Disposal of remote-handled LLW in concrete disposal vaults at RWMC will continue until the facility is full or until it must be closed in preparation for final remediation of the SDA (approximately at the end of fiscal year FY 2017). The continuing nuclear mission of INL, associated ongoing and planned operations, and Naval spent fuel activities at the Naval Reactors Facility (NRF) require continued capability to appropriately dispose of contact and remote handled LLW. A programmatic analysis of disposal alternatives for contact and remote-handled LLW generated at INL was conducted by the INL contractor in Fiscal Year 2006; subsequent evaluations were completed in Fiscal Year 2007. The result of these analyses was a recommendation to the Department of Energy (DOE) that all contact-handled LLW generated after September 30, 2008, be disposed offsite, and that DOE proceed with a capital project to establish replacement remote-handled LLW disposal capability. An analysis of the alternatives for providing replacement remote-handled LLW disposal capability has been performed to support Critical Decision-1. The highest ranked alternative to provide this required capability has been determined to be the development of a new onsite remote-handled LLW disposal facility to replace the existing remote-handled LLW disposal vaults at the SDA. Several offsite DOE

  4. Colonic potassium handling

    DEFF Research Database (Denmark)

    Sørensen, Mads Vaarby; Matos, Joana E.; Prætorius, Helle

    2010-01-01

    Homeostatic control of plasma K+ is a necessary physiological function. The daily dietary K+ intake of approximately 100 mmol is excreted predominantly by the distal tubules of the kidney. About 10% of the ingested K+ is excreted via the intestine. K+ handling in both organs is specifically...

  5. Handling of bulk solids theory and practice

    CERN Document Server

    Shamlou, P A

    1990-01-01

    Handling of Bulk Solids provides a comprehensive discussion of the field of solids flow and handling in the process industries. Presentation of the subject follows classical lines of separate discussions for each topic, so each chapter is self-contained and can be read on its own. Topics discussed include bulk solids flow and handling properties; pressure profiles in bulk solids storage vessels; the design of storage silos for reliable discharge of bulk materials; gravity flow of particulate materials from storage vessels; pneumatic transportation of bulk solids; and the hazards of solid-mater

  6. Solid waste handling

    Energy Technology Data Exchange (ETDEWEB)

    Parazin, R.J.

    1995-05-31

    This study presents estimates of the solid radioactive waste quantities that will be generated in the Separations, Low-Level Waste Vitrification and High-Level Waste Vitrification facilities, collectively called the Tank Waste Remediation System Treatment Complex, over the life of these facilities. This study then considers previous estimates from other 200 Area generators and compares alternative methods of handling (segregation, packaging, assaying, shipping, etc.).

  7. Uranium hexafluoride handling. Proceedings

    Energy Technology Data Exchange (ETDEWEB)

    1991-12-31

    The United States Department of Energy, Oak Ridge Field Office, and Martin Marietta Energy Systems, Inc., are co-sponsoring this Second International Conference on Uranium Hexafluoride Handling. The conference is offered as a forum for the exchange of information and concepts regarding the technical and regulatory issues and the safety aspects which relate to the handling of uranium hexafluoride. Through the papers presented here, we attempt not only to share technological advances and lessons learned, but also to demonstrate that we are concerned about the health and safety of our workers and the public, and are good stewards of the environment in which we all work and live. These proceedings are a compilation of the work of many experts in that phase of world-wide industry which comprises the nuclear fuel cycle. Their experience spans the entire range over which uranium hexafluoride is involved in the fuel cycle, from the production of UF{sub 6} from the naturally-occurring oxide to its re-conversion to oxide for reactor fuels. The papers furnish insights into the chemical, physical, and nuclear properties of uranium hexafluoride as they influence its transport, storage, and the design and operation of plant-scale facilities for production, processing, and conversion to oxide. The papers demonstrate, in an industry often cited for its excellent safety record, continuing efforts to further improve safety in all areas of handling uranium hexafluoride. Selected papers were processed separately for inclusion in the Energy Science and Technology Database.

  8. Feedstock storage, handling and processing

    Energy Technology Data Exchange (ETDEWEB)

    Egg, R.P.; Coble, C.G.; Engler, C.R. (Texas A and M Univ., College Station, TX (United States). Dept. of Agricultural Engineering); Lewis, D.H. (Texas A and M Univ., College Station, TX (United States). Dept. of Veterinary Microbiology and Parasitology)

    1993-01-01

    This paper is a review of the technology and research covering components of a methane from biomass system between the field and the digester. It deals primarily with sorghum as a feedstock and focuses on research conducted by the Texas Agricultural Experiment Station. Subjects included in this paper are harvesting, hay storage, ansiling, materials handling, pumping and hydraulic characteristics, hydraulic conductivity, pressure/density relationship, and biological pretreatment. This paper is not a comprehensive design manual; however, design equations and coefficients for sorghum are presented, where available, along with references describing the development and application of design models. (author)

  9. Basics for Handling Food Safely

    Science.gov (United States)

    ... o a rm ct a s tion Basics for Handling Food Safely Safe steps in food handling, cooking, and storage are essential to prevent foodborne ... and soap for 20 seconds before and after handling food. · Don’t cross-contaminate. Keep raw meat, ...

  10. Students' Strategies for Exception Handling

    Science.gov (United States)

    Rashkovits, Rami; Lavy, Ilana

    2011-01-01

    This study discusses and presents various strategies employed by novice programmers concerning exception handling. The main contributions of this paper are as follows: we provide an analysis tool to measure the level of assimilation of exception handling mechanism; we present and analyse strategies to handle exceptions; we present and analyse…

  11. Handling Qualities Implications for Crewed Spacecraft Operations

    Science.gov (United States)

    Bailey, Randall E.; Jackson, E. Bruce; Arthur, J. J.

    2012-01-01

    Abstract Handling qualities embody those qualities or characteristics of an aircraft that govern the ease and precision with which a pilot is able to perform the tasks required in support of an aircraft role. These same qualities are as critical, if not more so, in the operation of spacecraft. A research, development, test, and evaluation process was put into effect to identify, understand, and interpret the engineering and human factors principles which govern the pilot-vehicle dynamic system as they pertain to space exploration missions and tasks. Toward this objective, piloted simulations were conducted at the NASA Langley Research Center and Ames Research Center for earth-orbit proximity operations and docking and lunar landing. These works provide broad guidelines for the design of spacecraft to exhibit excellent handling characteristics. In particular, this work demonstrates how handling qualities include much more than just stability and control characteristics of a spacecraft or aircraft. Handling qualities are affected by all aspects of the pilot-vehicle dynamic system, including the motion, visual and aural cues of the vehicle response as the pilot performs the required operation or task. A holistic approach to spacecraft design, including the use of manual control, automatic control, and pilot intervention/supervision is described. The handling qualities implications of design decisions are demonstrated using these pilot-in-the-loop evaluations of docking operations and lunar landings.

  12. Chemical preparation of crystalline, nonmolecular solids, including solution-liquid-solid (SLS) growth of semiconductor fibers and varied routes to nanocrystalline molybdenum disilicide

    Science.gov (United States)

    Trentler, Timothy John

    New methods for the preparation of crystalline, nonmolecular solids under milder conditions and/or with control of crystallite size or morphology were developed in two separate projects. In one project, polycrystalline 13-15 semiconductor fibers (dimensions 10-100 nm x 50-1000 nm) were grown by solution-based chemical methods. Crystal precursor species of the general formula (Rsb{x}InEHsb{x}rbracksb{n}, where E is a pnictide and R is an alkyl group, were prepared by the phosphinolysis or arsinolysis of alkylindanes in aromatic solvents. Thermal decomposition of these precursors in solution, which was catalyzed by various protic reagents (MeOH, PhSH, Etsb2NH, or PhCOsb2H), resulted in crystalline InE when In metal was present in the form of submicron droplets dispersed in the solvent. Crystallization was determined to occur (at the lowest temperatures reported for 13-15 semiconductors, liquid-solid (SLS) mechanism reminiscent of vapor-liquid-solid (VLS) growth of single-crystal whiskers. Some analogous reactions were investigated in which t-Busb3Ga was mixed with the alkylindane in order to prepare ternary alloys (Insb{x}Gasb{1-x}As). Product crystallinity and composition was dependent on, though not exclusively determined by, the indane/gallane ratio. Crystals with composition within the miscibility gap for this alloy system were grown. The focus of the other project was the preparation of nanocrystalline (crystallite dimensions NaK alloy in an ultrasonically agitated hydrocarbon solvent followed by thermal processing (900sp°C) under vacuum to eliminate byproduct salts. MoSisb2 crystallites averaging 20-50 nm were obtained. Solvent degradation during this process resulted in the incorporation of substantial carbonaceous impurity (believed to be SiC) in these products. To eliminate the carbon, similar solventless reductions (without ultrasound) were conducted in molten magnesium, but average particle sizes have not been refined into the nanometer regime (currently

  13. Handling Qualities Optimization for Rotorcraft Conceptual Design

    Science.gov (United States)

    Lawrence, Ben; Theodore, Colin R.; Berger, Tom

    2016-01-01

    Over the past decade, NASA, under a succession of rotary-wing programs has been moving towards coupling multiple discipline analyses in a rigorous consistent manner to evaluate rotorcraft conceptual designs. Handling qualities is one of the component analyses to be included in a future NASA Multidisciplinary Analysis and Optimization framework for conceptual design of VTOL aircraft. Similarly, the future vision for the capability of the Concept Design and Assessment Technology Area (CD&A-TA) of the U.S Army Aviation Development Directorate also includes a handling qualities component. SIMPLI-FLYD is a tool jointly developed by NASA and the U.S. Army to perform modeling and analysis for the assessment of flight dynamics and control aspects of the handling qualities of rotorcraft conceptual designs. An exploration of handling qualities analysis has been carried out using SIMPLI-FLYD in illustrative scenarios of a tiltrotor in forward flight and single-main rotor helicopter at hover. Using SIMPLI-FLYD and the conceptual design tool NDARC integrated into a single process, the effects of variations of design parameters such as tail or rotor size were evaluated in the form of margins to fixed- and rotary-wing handling qualities metrics as well as the vehicle empty weight. The handling qualities design margins are shown to vary across the flight envelope due to both changing flight dynamic and control characteristics and changing handling qualities specification requirements. The current SIMPLI-FLYD capability and future developments are discussed in the context of an overall rotorcraft conceptual design process.

  14. Reactions and interactions in handling anticancer drugs.

    Science.gov (United States)

    D'Arcy, P F

    1983-01-01

    The clinical toxicity of anticancer drugs has been well documented with regard to the adverse effects of treatment in patients. However, many of these drugs have a direct irritant effect on the skin, eyes, mucous membranes, and other tissues. Handled without due care, especially when being prepared for injection, most cytotoxic drugs can cause local toxic or allergic reactions; they also present hazards of carcinogenicity and mutagenicity. This spectrum of potential risk should be kept in mind by personnel administering or handling these drugs, especially in oncology units where just a few individuals may routinely and frequently reconstitute many doses of cytotoxic agents. This is work in which the hospital pharmacist should and must be involved; indeed, many of the techniques and skills required are identical with those used in standard aseptic procedures for preparing pharmaceutical products. Pharmacy departments should take the initiative in making hospital staff aware of the potential risks of handling neoplastic agents, and they should spearhead a multidisciplinary assessment for producing local guidelines for working with these drugs. This article warns practitioners about the inherent dangers of these practitioner-drug interactions and suggests ways in which they may be reduced. Information is given in tabular form regarding recommended procedures for reconstituting 24 anticancer drugs and precautions to protect the personnel handling them, especially when there is spillage of powdered or liquid drugs. Also, guidelines are given about incompatibilities with admixtures of such drugs, and the literature is reviewed relative to recent developments in hospital pharmacy departments where reconstitution of anticancer drugs has been incorporated into existing intravenous fluid preparation/admixture units. Not only has this been shown to be safer and more effective in terms of time and labor, but also it has cut the cost of injectable cytotoxic drugs by an

  15. Transfer Area Mechanical Handling Calculation

    Energy Technology Data Exchange (ETDEWEB)

    B. Dianda

    2004-06-23

    This calculation is intended to support the License Application (LA) submittal of December 2004, in accordance with the directive given by DOE correspondence received on the 27th of January 2004 entitled: ''Authorization for Bechtel SAX Company L.L. C. to Include a Bare Fuel Handling Facility and Increased Aging Capacity in the License Application, Contract Number DE-AC28-01R W12101'' (Arthur, W.J., I11 2004). This correspondence was appended by further Correspondence received on the 19th of February 2004 entitled: ''Technical Direction to Bechtel SAIC Company L.L. C. for Surface Facility Improvements, Contract Number DE-AC28-OIRW12101; TDL No. 04-024'' (BSC 2004a). These documents give the authorization for a Fuel Handling Facility to be included in the baseline. The purpose of this calculation is to establish preliminary bounding equipment envelopes and weights for the Fuel Handling Facility (FHF) transfer areas equipment. This calculation provides preliminary information only to support development of facility layouts and preliminary load calculations. The limitations of this preliminary calculation lie within the assumptions of section 5 , as this calculation is part of an evolutionary design process. It is intended that this calculation is superseded as the design advances to reflect information necessary to support License Application. The design choices outlined within this calculation represent a demonstration of feasibility and may or may not be included in the completed design. This calculation provides preliminary weight, dimensional envelope, and equipment position in building for the purposes of defining interface variables. This calculation identifies and sizes major equipment and assemblies that dictate overall equipment dimensions and facility interfaces. Sizing of components is based on the selection of commercially available products, where applicable. This is not a specific recommendation for the future use

  16. Separation of three anthraquinone glycosides including two isomers by preparative high-performance liquid chromatography and high-speed countercurrent chromatography from Rheum tanguticum Maxim. ex Balf.

    Science.gov (United States)

    Chen, Tao; Li, Hongmei; Zou, Denglang; Liu, Yongling; Chen, Chen; Zhou, Guoying; Li, Yulin

    2016-08-01

    Anthraquinone glycosides, such as chrysophanol 1-O-β-d-glucoside, chrysophanol 8-O-β-d-glucoside, and physion 8-O-β-d-glucoside, are the accepted important active components of Rheum tanguticum Maxim. ex Balf. due to their pharmacological properties: antifungal, antimicrobial, cytotoxic, and antioxidant activities. However, an effective method for the separation of the above-mentioned anthraquinone glycosides from this herb is not currently available. Especially, greater difficulty existed in the separation of the two isomers chrysophanol 1-O-β-d-glucoside and chrysophanol 8-O-β-d-glucoside. This study demonstrated an efficient strategy based on preparative high-performance liquid chromatography and high-speed countercurrent chromatography for the separation of the above-mentioned anthraquinone glycosides from Rheum tanguticum Maxim.ex Balf.

  17. Rotorcraft handling-qualities design criteria development

    Science.gov (United States)

    Aiken, Edwin W.; Lebacqz, J. Victor; Chen, Robert T. N.; Key, David L.

    1988-01-01

    Joint NASA/Army efforts at the Ames Research Center to develop rotorcraft handling-qualities design criteria began in earnest in 1975. Notable results were the UH-1H VSTOLAND variable stability helicopter, the VFA-2 camera-and-terrain-board simulator visual system, and the generic helicopter real-time mathematical model, ARMCOP. An initial series of handling-qualities studies was conducted to assess the effects of rotor design parameters, interaxis coupling, and various levels of stability and control augmentation. The ability to conduct in-flight handling-qualities research was enhanced by the development of the NASA/Army CH-47 variable-stability helicopter. Research programs conducted using this vehicle include vertical-response investigations, hover augmentation systems, and the effects of control-force characteristics. The handling-qualities data base was judged to be sufficient to allow an update of the military helicopter handling-qualities specification, MIL-H-8501. These efforts, including not only the in-house experimental work but also contracted research and collaborative programs performed under the auspices of various international agreements. The report concludes by reviewing the topics that are currently most in need of work, and the plans for addressing these topics.

  18. Safe Handling of Cytotoxic Drugs and Risks of Occupational Exposure to Nursing Staffs

    Directory of Open Access Journals (Sweden)

    Somayeh Hanafi

    2016-05-01

    Full Text Available Background: Inherent toxicity of cytotoxic drugs is the basis for their potential adverse risks from occupational exposure to the nursing staff. In Iran, chemotherapy regimens are prescribed and administered according to the world updated protocols. But little is done regarding the protective standards in this field.Methods: An observational cross-sectional survey was conducted among nurses who work in three tertiary care teaching hospitals in Tehran, Iran in 2012. All participants worked in one of the hospital wards handling cytotoxic drugs (preparation and administration. A questionnaire was used for interviewing all subjects, and observing them preparing and administering the drugs. We examined all adverse effects associated with handling of antineoplastic drugs.Results: Totally 270 adverse reactions were reported. The most frequently reported adverse effects included headache and vertigo (40 cases, hair loss (36 cases, skin rashes and itching (31 cases, and burning sensation in eyes (31 cases. In all hospital wards, the standards were met in not more than 50% of the items.Conclusion: Monitoring the personnel who are directly involved in handling of cytotoxic drugs is of great importance. Furthermore, educating the personnel in the field of standards of cytotoxic drugs handling could increase the nursing staff’s knowledge regarding these drugs’ adverse reactions.

  19. A Scintillator Purification Plant and Fluid Handling System for SNO+

    CERN Document Server

    Ford, Richard J

    2015-01-01

    A large capacity purification plant and fluid handling system has been constructed for the SNO+ neutrino and double-beta decay experiment, located 6800 feet underground at SNOLAB, Canada. SNO+ is a refurbishment of the SNO detector to fill the acrylic vessel with liquid scintillator based on Linear Alkylbenzene (LAB) and 2 g/L PPO, and also has a phase to load natural tellurium into the scintillator for a double-beta decay experiment with 130Te. The plant includes processes multi-stage dual-stream distillation, column water extraction, steam stripping, and functionalized silica gel adsorption columns. The plant also includes systems for preparing the scintillator with PPO and metal-loading the scintillator for double-beta decay exposure. We review the basis of design, the purification principles, specifications for the plant, and the construction and installations. The construction and commissioning status is updated.

  20. Trends in Modern Exception Handling

    Directory of Open Access Journals (Sweden)

    Marcin Kuta

    2003-01-01

    Full Text Available Exception handling is nowadays a necessary component of error proof information systems. The paper presents overview of techniques and models of exception handling, problems connected with them and potential solutions. The aspects of implementation of propagation mechanisms and exception handling, their effect on semantics and general program efficiency are also taken into account. Presented mechanisms were adopted to modern programming languages. Considering design area, formal methods and formal verification of program properties we can notice exception handling mechanisms are weakly present what makes a field for future research.

  1. Identification of unique food handling practices that could represent food safety risks for minority consumers.

    Science.gov (United States)

    Henley, Shauna C; Stein, Susan E; Quinlan, Jennifer J

    2012-11-01

    Foodborne illness caused by Salmonella and Campylobacter is a concern for consumers, and there is evidence that minority racial-ethnic populations experience greater rates of illness because of these pathogens. The limited body of research concerning food safety knowledge and practices among minority consumers has focused more on general food safety knowledge than on culturally specific food handling practices. The purpose of the research reported here was to explore food handling behaviors of minority racial-ethnic consumers through in-depth discussions in focus group settings. In this way, we hoped to identify potential unique, previously unidentified food handling practices among these consumers. Nine focus groups were held in Philadelphia, PA. Three focus groups were conducted with African American consumers, three with Hispanic consumers, and three with Asian consumers. In all, 56 consumers participated. Data were recorded, transcribed, and analyzed for unique and potentially unsafe food handling behaviors. Potentially unsafe food handling practices identified among all three groups included extended time to transport food from retail to home and washing of raw poultry. Culturally unique behaviors within groups included (i) using hot water (Asian, Hispanic) or acidic solutions (African American, Hispanic) to clean raw poultry, (ii) purchasing live poultry (Asian, Hispanic), (iii) cooking poultry overnight (African American), and (iv) preparing bite-size pieces of meat prior to cooking (Asian, Hispanic). To have focus groups include a limited number of participants and nonrandom sampling means that these themes and trends cannot be extrapolated to represent food mishandling among these populations in general. Results presented here allow modification of an existing food safety survey to identify the prevalence of these food handling practices among consumers of different demographics.

  2. Pre-flight report on cultured human embryonic kidney cell handling and cell electrophoresis. Prepared prior to continuous-flow electrophoretic separation experiments aboard space shuttle flight STS-8

    Science.gov (United States)

    Todd, P. W.; Sarnoff, B. E.; Li, Z. K.

    1985-01-01

    Studies of the physical properties of continuous-flow zero-G electrophoretic separator (CFES) buffer, the electrokinetic properties of human erythrocytes in the CFES buffer, the electrokinetic properties of human embryonic kidney cells in the CFES buffer, and the viability and yield of human embryonc kidney cells subjected to flight handling procedures are discussed. In general, the procedure for cell handling and electrophoresis of HEK-8514 cells in 1st or 2nd passage on STS-8 is acceptable if executed properly. The CFES buffer has ionic strength that is barely compatible with cell viability and membrane stability, as seen in experiments with human erythrocytes and trypan-blue staining of human kidney cells. Cells suspended in 10% dialysed horse serum for 3 days in the cold appear to be more stable than freshly trypsinized cells. 10% horse serum appears to be superior to 5% horse serum for this purpose. The mean absolute raw mobility of HEK-8514 cells in CFES buffer at 6 degrees, conductivity 0.055 mmho/cm, is 1.1 to 1.4 um-cm/V-sec, with a range of nearly a whole mobility unit.

  3. REMOTE HANDLING ARRANGEMENTS

    Science.gov (United States)

    Ginns, D.W.

    1958-04-01

    A means for handling remotely a sample pellet to be irradiated in a nuclear reactor is proposed. It is comprised essentially of an inlet tube extending through the outer shield of the reactor and being inclined so that its outer end is at a higher elevation than its inner end, an outlet tube extending through the outer shield being inclined so that its inner end is at a higher elevation than its outer end, the inner ends of these two tubes being interconnected, and a straight tube extending through the outer shield and into the reactor core between the inlet and outlet tubes and passing through the juncture of said inner ends. A rod-like member is rotatably and slidely operated within the central straight tube and has a receptacle on its inner end for receiving a sample pellet from the inlet tube. The rod member is operated to pick up a sample pellet from the inlet tube, carry the sample pellet into the irradiating position within the core, and return to the receiving position where it is rotated to dump the irradiated pellet into the outlet tube by which it is conveyed by gravity to the outside of the reactor. Stop members are provided in the inlet tube, and electrical operating devices are provided to control the sequence of the operation automatically.

  4. PR[superscript 2]EPS: Preparation, Recruitment, Retention and Excellence in the Physical Sciences, Including Engineering. A Report on the 2004, 2005 and 2006 Science Summer Camps

    Science.gov (United States)

    Bachman, Nancy J.; Bischoff, Paul J.; Gallagher, Hugh; Labroo, Sunil; Schaumloffel, John C.

    2008-01-01

    Now in its fourth year, PR[superscript 2]EPS is a National Science Foundation funded initiative designed to recruit high school students to attend college majoring in the physical sciences, including engineering and secondary science education, and to help ensure their retention within the program until graduation. A central feature of the…

  5. Confluence Modulo Equivalence in Constraint Handling Rules

    DEFF Research Database (Denmark)

    Christiansen, Henning; Kirkeby, Maja Hanne

    2014-01-01

    Previous results on confluence for Constraint Handling Rules, CHR, are generalized to take into account user-defined state equivalence relations. This allows a much larger class of programs to enjoy the ad- vantages of confluence, which include various optimization techniques and simplified corre...

  6. Railcar handling systems - designs for individual solutions

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-04-01

    The article examines the latest state of the art developments in railcar handling technology, with profiles of leading equipment suppliers in this field and recent projects completed worldwide. Equipment covered includes: railcar discharge systems; rotary dumpers; side discharge dumpers; and railcar loading systems. 2 figs., 7 photos.

  7. DOE handbook: Tritium handling and safe storage

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-03-01

    The DOE Handbook was developed as an educational supplement and reference for operations and maintenance personnel. Most of the tritium publications are written from a radiological protection perspective. This handbook provides more extensive guidance and advice on the null range of tritium operations. This handbook can be used by personnel involved in the full range of tritium handling from receipt to ultimate disposal. Compliance issues are addressed at each stage of handling. This handbook can also be used as a reference for those individuals involved in real time determination of bounding doses resulting from inadvertent tritium releases. This handbook provides useful information for establishing processes and procedures for the receipt, storage, assay, handling, packaging, and shipping of tritium and tritiated wastes. It includes discussions and advice on compliance-based issues and adds insight to those areas that currently possess unclear DOE guidance.

  8. Building a framework for ergonomic research on laparoscopic instrument handles.

    Science.gov (United States)

    Li, Zheng; Wang, Guohui; Tan, Juan; Sun, Xulong; Lin, Hao; Zhu, Shaihong

    2016-06-01

    Laparoscopic surgery carries the advantage of minimal invasiveness, but ergonomic design of the instruments used has progressed slowly. Previous studies have demonstrated that the handle of laparoscopic instruments is vital for both surgical performance and surgeon's health. This review provides an overview of the sub-discipline of handle ergonomics, including an evaluation framework, objective and subjective assessment systems, data collection and statistical analyses. Furthermore, a framework for ergonomic research on laparoscopic instrument handles is proposed to standardize work on instrument design.

  9. Development and evaluation of online video teaching resources to enhance student knowledge of livestock handling.

    Science.gov (United States)

    Klupiec, C; Pope, S; Taylor, R; Carroll, D; Ward, M H; Celi, P

    2014-07-01

    To evaluate the effectiveness of online audiovisual materials to support the acquisition of animal handling skills by students of veterinary and animal science. A series of video clips (Livestock Handling modules) demonstrating livestock handling procedures was created and delivered online to students enrolled in the Faculty of Veterinary Science, University of Sydney. The effectiveness of these modules for supporting student learning was evaluated via an online survey. The survey also sought feedback on how students could be better prepared for handling livestock. The survey indicated that students found the videos a useful part of their learning experience, particularly by familiarising them with correct handling procedures and emphasising the importance of safety when handling livestock. Students also highlighted that online delivery supported flexible learning. Suggested improvements of the Livestock Handling modules centred around broadening the content of the videos and improving the user-friendliness of online access. Student feedback regarding how the Faculty could better prepare them for livestock handling was dominated by requests for more opportunities to practise animal handling using live animals. The Livestock Handling audiovisual tool is a valuable supplementary resource for developing students' proficiency in safe and effective handling of livestock. However, the results also clearly reveal a perception by students that more hands-on experience is required for acquisition of animal handling skills. These findings will inform future development of the Faculty's animal handling program. © 2014 Australian Veterinary Association.

  10. Parallel Handling of Integrity Constraints

    NARCIS (Netherlands)

    Grefen, P.W.P.J.; Flokstra, Jan; Apers, Peter M.G.

    1990-01-01

    Integrity constraints form an important part of a data model. Therefore, a complete integrity constraint handling subsystem is considered an important part of any modern DBMS. In implementing an integrity constraint handling subsystem, there are two major problem areas: providing enough functionalit

  11. Assessment of Issue Handling Efficiency

    NARCIS (Netherlands)

    Luijten, B.; Visser, J.; Zaidman, A.

    2013-01-01

    We mined the issue database of GNOME to assess how issues are handled. How many issues are submitted and resolved? Does the backlog grow or decrease? How fast are issues resolved? Does issue resolution speed increase or decrease over time? In which subproject are issues handled most efficiently? To

  12. Assessment of Issue Handling Efficiency

    NARCIS (Netherlands)

    Luijten, B.; Visser, J.; Zaidman, A.

    2013-01-01

    We mined the issue database of GNOME to assess how issues are handled. How many issues are submitted and resolved? Does the backlog grow or decrease? How fast are issues resolved? Does issue resolution speed increase or decrease over time? In which subproject are issues handled most efficiently? To

  13. Effects of handling on fear reactions in young Icelandic horses

    DEFF Research Database (Denmark)

    Marsbøll, Anna Feldberg; Christensen, Janne Winther

    2015-01-01

    Reasons for performing the study Inclusion of objective temperament tests at practical horse breeding evaluations is of increased interest. It has been debated whether such tests may involve human handling, since there may be considerable differences in horses' handling experience. Objectives...... of fearfulness. Known handlers may ‘mask’ behavioural responses of horses in fear tests and thus handling by a known handler during testing may not be appropriate for objective evaluation of fearfulness in a practical situation....... To investigate the effect of a short-term standardised handling procedure on reactions of young horses in 2 types of fear tests (including and excluding human handling). Study design An experimental study with 3-year-old Icelandic horses (n = 24). Methods Handled horses (n = 12) were trained according...

  14. CLINICAL WASTE HANDLING AND OBSTACLES IN MALAYSIA

    Directory of Open Access Journals (Sweden)

    Shaidatul Shida Razali

    2010-12-01

    Full Text Available As in many other developing countries, the generation of clinical waste in Malaysia has increased significantly over the last few decades. Even though the serious impact of the clinical waste on human beings and the environment is significant, only minor attention is directed to its proper handling and legal aspects. This study seeks to examine the management of clinical waste in Selangor’s government hospitals as well as problems that arise from the current practice of clinical waste management. A depth interview with the responsible concession who handles the clinical waste management in those hospitals also has been taken. In general, it was found that the consortium’s administration was reasonably aware of the importance of clinical waste management. However, significant voids were presented that need to be addressed in future including efficient segregation, better handling and transfer means, as well as the need for training and awareness programs for the personnel. Other obstacles faced by consortiums were to handle the clinical waste including the operational costs. Waste minimizing and recycling, as well as the alternative treatment methods for incineration are regarded to be major challenges in the future.

  15. Lunar Materials Handling System Project

    Data.gov (United States)

    National Aeronautics and Space Administration — The Lunar Materials Handling System (LMHS) is a method for transfer of lunar soil into and out of process equipment in support of in situ resource utilization...

  16. Tritium handling in vacuum systems

    Energy Technology Data Exchange (ETDEWEB)

    Gill, J.T. [Monsanto Research Corp., Miamisburg, OH (United States). Mound Facility; Coffin, D.O. [Los Alamos National Lab., NM (United States)

    1986-10-01

    This report provides a course in Tritium handling in vacuum systems. Topics presented are: Properties of Tritium; Tritium compatibility of materials; Tritium-compatible vacuum equipment; and Tritium waste treatment.

  17. Solidex 88: solids handling conference

    Energy Technology Data Exchange (ETDEWEB)

    1988-01-01

    Papers are presented under the session headings: BMHB (British Materials Handling Board) - tackling user problems; feeding pneumatic conveying systems - matching the hardware to the product; and solutions to some operational problems.

  18. Lunar Materials Handling System Project

    Data.gov (United States)

    National Aeronautics and Space Administration — The Lunar Materials Handling System (LMHS) is a method for transfer of bulk materials and products into and out of process equipment in support of lunar and Mars in...

  19. Order Handling in Convergent Environments

    CERN Document Server

    Vrtanoski, Jordan

    2012-01-01

    The rapid development of IT&T technology had big impact on the traditional telecommunications market, transforming it from monopolistic market to highly competitive high-tech market where new services are required to be created frequently. This paper aims to describe a design approach that puts order management process (as part of enterprise application integration) in function of rapid service creation. In the text we will present a framework for collaborative order handling supporting convergent services. The design splits the order handling processes in convergent environments in three business process groups: order capture, order management and order fulfillment. The paper establishes abstract framework for order handling and provides design guidelines for transaction handling implementation based on the checkpoint and inverse command strategy. The proposed design approach is based in a convergent telecommunication environment. Same principles are applicable in solving problems of collaboration in fun...

  20. Towards integrated microliquid handling systems

    NARCIS (Netherlands)

    Elwenspoek, M.; Lammerink, T.S.J.; Miyake, R.; Fluitman, J.H.J.

    1994-01-01

    In this paper we describe components for integrated microliquid handling systems such as fluid injection analysis, and first results of planar integration of components. The components discussed are channels, passive and active valves, actuators for micropumps, micromixers, microflow sensors, optica

  1. WASTE HANDLING BUILDING FIRE PROTECTION SYSTEM DESCRIPTION DOCUMENT

    Energy Technology Data Exchange (ETDEWEB)

    J. D. Bigbee

    2000-06-21

    The Waste Handling Building Fire Protection System provides the capability to detect, control, and extinguish fires and/or mitigate explosions throughout the Waste Handling Building (WHB). Fire protection includes appropriate water-based and non-water-based suppression, as appropriate, and includes the distribution and delivery systems for the fire suppression agents. The Waste Handling Building Fire Protection System includes fire or explosion detection panel(s) controlling various detectors, system actuation, annunciators, equipment controls, and signal outputs. The system interfaces with the Waste Handling Building System for mounting of fire protection equipment and components, location of fire suppression equipment, suppression agent runoff, and locating fire rated barriers. The system interfaces with the Waste Handling Building System for adequate drainage and removal capabilities of liquid runoff resulting from fire protection discharges. The system interfaces with the Waste Handling Building Electrical Distribution System for power to operate, and with the Site Fire Protection System for fire protection water supply to automatic sprinklers, standpipes, and hose stations. The system interfaces with the Site Fire Protection System for fire signal transmission outside the WHB as needed to respond to a fire emergency, and with the Waste Handling Building Ventilation System to detect smoke and fire in specific areas, to protect building high-efficiency particulate air (HEPA) filters, and to control portions of the Waste Handling Building Ventilation System for smoke management and manual override capability. The system interfaces with the Monitored Geologic Repository (MGR) Operations Monitoring and Control System for annunciation, and condition status.

  2. Grain Handling and Storage Safety

    OpenAIRE

    Webster, Jill, Ph.D.

    2005-01-01

    Agricultural Health and Safety Fact Sheet AHS-02 Grain Handling and Storage Safety Jill Webster Ph.D., S. Christian Mariger, Graduate Assistant Agricultural Systems Technology and Education There are several hazards that should be considered when working with grain. Storage structures, handling equipment, and the grain itself have all caused serious injuries and deaths. Storage structures (bins, silos, and granaries), like all confined spaces, have significant hazards associated with them. Be...

  3. Civilsamfundets ABC: H for Handling

    DEFF Research Database (Denmark)

    Lund, Anker Brink; Meyer, Gitte

    2015-01-01

    Hvad er civilsamfundet? Anker Brink Lund og Gitte Meyer fra CBS Center for Civil Society Studies gennemgår civilsamfundet bogstav for bogstav. Vi er nået til H for Handling.......Hvad er civilsamfundet? Anker Brink Lund og Gitte Meyer fra CBS Center for Civil Society Studies gennemgår civilsamfundet bogstav for bogstav. Vi er nået til H for Handling....

  4. SAFE HANDLING OF FOODS

    Science.gov (United States)

    Microbial food-borne illnesses pose a significant health problem in Japan. In 1996 the world's largest outbreak of Escherichia coli food illness occurred in Japan. Since then, new regulatory measures were established, including strict hygiene practices in meat and food processi...

  5. Storage and Materials Handling

    Science.gov (United States)

    1979-09-01

    32-35 .............. 4 Cookie dough .............................. 32 .............. 90 Corn on the cob, top-iced . ........ 31 32 95 4-8...180 Cream: half and half, including filled 31 32-35 .............. 7 sour , cultured ...................... 31 32-35 ............. 14...Swells, springers and flippers are musty and sour . It should be emphasized that de- caused either by chemical or bacterial action, or by hydrated

  6. Consequences of introducing requirements for tanks prepared for solar heating in the building regulations including examinations of bacteria risks; Konsekvenser ved solvarmeforberedte beholdere i bygningsreglementet herunder undersoegelse af risici for bakteriegener

    Energy Technology Data Exchange (ETDEWEB)

    Ellehauge, K.; Kaersgaard, K. [Teknologisk Inst., SolEnergiCentret, Taastrup (Denmark); Bagh, L. [Teknologisk Inst., Miljoedivisionen (Denmark)

    2000-07-01

    A larger dissemination of solar heating units must be expected, if requirements for tanks prepared for solar heating are introduced in the building regulations. However, this may have effects, which have to be discussed beforehand, just as it has to be decided how the regulations can be put into practice. 1) The aim is to examine and discuss the consequences of introducing requirements for tanks prepared for solar heating in the building regulations including connections with other legislation, potential, consequences for the building services sector and proposals for rules in the building regulations (exceptions etc.) 2) Furthermore, the aim is to explain the risk of bacteria in tanks prepared for solar heating according to existing or new additional studies. It must be explained whether tanks prepared for solar heating will result in an increased number of bacteria in the water compared to traditional hot water tanks and - if possible - whether the change is caused by the increased volume of the tank (the water stays in the tank for a longer period) or changed temperature conditions which favours growth of bacteria at a certain incubation temperature. (EHS)

  7. Síndrome HaNDL / HaNDL Syndrome / Síndrome HaNDL

    Directory of Open Access Journals (Sweden)

    Camilo Ernesto Barros-Gutiérrez, MD., Esp.

    2015-03-01

    Full Text Available Introducción: El Síndrome HaNDL (Headache and neurologic deficits with cerebroespinal fluid lymphocytosis por sus siglas en inglés, es una patología que cursa con cefalea, focalización neurológica y linfocitosis en el líquido cefalorraquídeo. Objetivo: este artículo busca presentar un caso de Síndrome de HaNDL, puesto que esta condición nosológica implica un reto diagnóstico. Resultados y conclusiones: Se presenta el caso de un paciente con diagnóstico de síndrome de HaNDL los hallazgos al examen físico y del líquido cefalorraquídeo. [Barros-Gutiérrez CE, Silva-Monsalve E, Gualtero-Trujillo S. Síndrome HaNDL. MedUNAB 2015; 17(3: xx-xx]. Introduction: The syndrome of transient Headache and Neurological Deficits with cerebrospinal fluid Lymphocytosis, is a pathology that presents cephalalgia, neurological focalization and lymphocytes in the cerebrospinal fluid. Objective: This article presents a HaNDL Syndrome case, since this nosological condition implies a diagnostic challenge. Results and conclusions: A case of a patient with HaNDL syndrome diagnosis, physical examination findings and cerebrospinal fluid are presented. [Barros-Gutiérrez CE, Silva-Monsalve E, Gualtero-Trujillo S. HaNDL Syndrome. MedUNAB 2015; 17(3: xx-xx]. Introdução: A síndrome de HaNDL (Headache and neurologic déficits with cerebrospinal fluid lymphocytosis por sua sigla em inglês é uma doença que causa dor de cabeça, foco neurológico e linfocitose no líquido cefalorraquidiano. Objetivo: Este artigo tem como objetivo apresentar um caso de Síndrome de HaNDL, uma vez que esta condição nosológica envolve um desafio diagnóstico. Resultados e conclusões: Apresenta-se o caso de um paciente diagnosticado com a síndrome de HaNDL, o encontrado no exame físico e o líquido cefalorraquidiano. [Barros-Gutiérrez CE, Silva-Monsalve E, Gualtero-Trujillo S. Síndrome HaNDL. MedUNAB 2015; 17(3: xx-xx].

  8. A prospective three-step intervention study to prevent medication errors in drug handling in paediatric care.

    Science.gov (United States)

    Niemann, Dorothee; Bertsche, Astrid; Meyrath, David; Koepf, Ellen D; Traiser, Carolin; Seebald, Katja; Schmitt, Claus P; Hoffmann, Georg F; Haefeli, Walter E; Bertsche, Thilo

    2015-01-01

    To prevent medication errors in drug handling in a paediatric ward. One in five preventable adverse drug events in hospitalised children is caused by medication errors. Errors in drug prescription have been studied frequently, but data regarding drug handling, including drug preparation and administration, are scarce. A three-step intervention study including monitoring procedure was used to detect and prevent medication errors in drug handling. After approval by the ethics committee, pharmacists monitored drug handling by nurses on an 18-bed paediatric ward in a university hospital prior to and following each intervention step. They also conducted a questionnaire survey aimed at identifying knowledge deficits. Each intervention step targeted different causes of errors. The handout mainly addressed knowledge deficits, the training course addressed errors caused by rule violations and slips, and the reference book addressed knowledge-, memory- and rule-based errors. The number of patients who were subjected to at least one medication error in drug handling decreased from 38/43 (88%) to 25/51 (49%) following the third intervention, and the overall frequency of errors decreased from 527 errors in 581 processes (91%) to 116/441 (26%). The issue of the handout reduced medication errors caused by knowledge deficits regarding, for instance, the correct 'volume of solvent for IV drugs' from 49-25%. Paediatric drug handling is prone to errors. A three-step intervention effectively decreased the high frequency of medication errors by addressing the diversity of their causes. Worldwide, nurses are in charge of drug handling, which constitutes an error-prone but often-neglected step in drug therapy. Detection and prevention of errors in daily routine is necessary for a safe and effective drug therapy. Our three-step intervention reduced errors and is suitable to be tested in other wards and settings. © 2014 John Wiley & Sons Ltd.

  9. NB Power`s fish handling facilities

    Energy Technology Data Exchange (ETDEWEB)

    Hickman, C. N. [New Brunswick Power, Fredericton, NB (Canada)

    1995-12-31

    Fish handling facilities at the various hydroelectric power generating stations of New Brunswick Power on the St. John River, were described. The facilities described included the fish hoist at the Beechwood Generating Station , the fish ladder at the Tobique Generating Station and a trap and truck operation at the Mactaquac Station. Details of operating arrangements were provided. Operating issues, solutions and ongoing efforts to improve operations further, were discussed. 4 refs., 4 figs.

  10. Tool handling robot system; Tool handling robot system

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-03-10

    As an example of the delivery of industrial use automation equipment by Meidensha Corp., the paper introduced a tool handling robot system. The system is a tool handling robot of case processing use FMS (flexible manufacturing system). This is a system which exchanges tool automatically according to the From To order from the managing computer using the ceiling running robot between five horizontal type machining centers and more than 800 collective tool stockers. The structure of the system is as follows: tool handling robot (MHR-400), robot controller (meirocs-F), tool hand, robot running unit, tool stocker (for 844 tools), five life tool exchange trucks, tool truck lifting unit, system control panel. (NEDO)

  11. Conceptual Design Report for the Remote-Handled Low-Level Waste Disposal Project

    Energy Technology Data Exchange (ETDEWEB)

    David Duncan

    2011-05-01

    This conceptual design report addresses development of replacement remote-handled low-level waste disposal capability for the Idaho National Laboratory. Current disposal capability at the Radioactive Waste Management Complex is planned until the facility is full or until it must be closed in preparation for final remediation (approximately at the end of Fiscal Year 2017). This conceptual design report includes key project assumptions; design options considered in development of the proposed onsite disposal facility (the highest ranked alternative for providing continued uninterrupted remote-handled low level waste disposal capability); process and facility descriptions; safety and environmental requirements that would apply to the proposed facility; and the proposed cost and schedule for funding, design, construction, and operation of the proposed onsite disposal facility.

  12. Conceptual Design Report for the Remote-Handled Low-Level Waste Disposal Project

    Energy Technology Data Exchange (ETDEWEB)

    Lisa Harvego; David Duncan; Joan Connolly; Margaret Hinman; Charles Marcinkiewicz; Gary Mecham

    2011-03-01

    This conceptual design report addresses development of replacement remote-handled low-level waste disposal capability for the Idaho National Laboratory. Current disposal capability at the Radioactive Waste Management Complex is planned until the facility is full or until it must be closed in preparation for final remediation (approximately at the end of Fiscal Year 2017). This conceptual design report includes key project assumptions; design options considered in development of the proposed onsite disposal facility (the highest ranked alternative for providing continued uninterrupted remote-handled low level waste disposal capability); process and facility descriptions; safety and environmental requirements that would apply to the proposed facility; and the proposed cost and schedule for funding, design, construction, and operation of the proposed onsite disposal facility.

  13. TITLE III EVALUATION REPORT FOR THE MATERIAL AND PERSONNEL HANDLING SYSTEM

    Energy Technology Data Exchange (ETDEWEB)

    T. A. Misiak

    1998-05-21

    This Title III Evaluation Report (TER) provides the results of an evaluation that was conducted on the Material and Personnel Handling System. This TER has been written in accordance with the ''Technical Document Preparation Plan for the Mined Geologic Disposal System Title III Evaluation Reports'' (BA0000000-01717-4600-00005 REV 03). The objective of this evaluation is to provide recommendations to ensure consistency between the technical baseline requirements, baseline design, and the as-constructed Material and Personnel Handling System. Recommendations for resolving discrepancies between the as-constructed system, the technical baseline requirements, and the baseline design are included in this report. Cost and Schedule estimates are provided for all recommended modifications.

  14. Conceptual Design Report for Remote-Handled Low-Level Waste Disposal Facility

    Energy Technology Data Exchange (ETDEWEB)

    Lisa Harvego; David Duncan; Joan Connolly; Margaret Hinman; Charles Marcinkiewicz; Gary Mecham

    2010-10-01

    This conceptual design report addresses development of replacement remote-handled low-level waste disposal capability for the Idaho National Laboratory. Current disposal capability at the Radioactive Waste Management Complex is planned until the facility is full or until it must be closed in preparation for final remediation (approximately at the end of Fiscal Year 2017). This conceptual design report includes key project assumptions; design options considered in development of the proposed onsite disposal facility (the highest ranked alternative for providing continued uninterrupted remote-handled low level waste disposal capability); process and facility descriptions; safety and environmental requirements that would apply to the proposed facility; and the proposed cost and schedule for funding, design, construction, and operation of the proposed onsite disposal facility.

  15. Food Consumption and Handling Survey for Quantitative Microbiological Consumer Phase Risk Assessments.

    Science.gov (United States)

    Chardon, Jurgen; Swart, Arno

    2016-07-01

    In the consumer phase of a typical quantitative microbiological risk assessment (QMRA), mathematical equations identify data gaps. To acquire useful data we designed a food consumption and food handling survey (2,226 respondents) for QMRA applications that is especially aimed at obtaining quantitative data. For a broad spectrum of food products, the survey covered the following topics: processing status at retail, consumer storage, preparation, and consumption. Questions were designed to facilitate distribution fitting. In the statistical analysis, special attention was given to the selection of the most adequate distribution to describe the data. Bootstrap procedures were used to describe uncertainty. The final result was a coherent quantitative consumer phase food survey and parameter estimates for food handling and consumption practices in The Netherlands, including variation over individuals and uncertainty estimates.

  16. Steller sea lion capture, marking, and handling data across their range 1985-2014

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This database contains information on individual sea lions that were marked or handled from 1985-2014. Individuals were handled for various projects including vital...

  17. Ergonomic redesign and evaluation of a clamping tool handle.

    Science.gov (United States)

    Jung, Myung-Chul; Hallbeck, M Susan

    2005-09-01

    The handle of a commercial bar clamp was redesigned using ergonomic principles and then compared with an original clamp. Ten male and ten female students participated in simulated clamping tasks under various conditions, including different clamping heights, clamping methods, and handle-gripping methods, with respect to the dependent variables of clamping and handle-squeezing forces. The results showed that the redesigned clamp produced larger clamping force with lower handle-squeezing forces than the original clamp. As expected, males exerted more force than females in both clamping and squeezing forces. A pistol grip method was superior to an upside-down handle-gripping method. Two-handed operation was recommended for this type of clamp by simultaneously pulling the trigger and sliding the bar in order to initially tighten around objects. This study shows that the application of ergonomic guidelines increases the efficiency and usability of manual handtools.

  18. Anatomical practices of preserving, handling and management of ...

    African Journals Online (AJOL)

    Anatomical practices of preserving, handling and management of human ... out with the aim of proposing an effective system of taking care of human remains. ... includes established lifeless or dead whole human body otherwise known as ...

  19. Værk som handling

    DEFF Research Database (Denmark)

    Jalving, Camilla

    Hvordan kan et kunstværk være en handling? Hvad er performativ billedkunst, og hvad menes der egentlig med ordet ´performativitet´? Det er nogle af de spørgsmål, bogen Værk som handling griber fat i. Mens performativitet i løbet af de sidste ti år er blevet et bredt anvendt begreb i kulturteorien...... mellem værket som objekt og som handling. Bogens værkanalyser orienterer sig derfor både mod, hvad kunstværket er, og hvordan det er: Hvordan virker det, hvordan stiller det sig frem, hvordan producerer det betydning, hvordan skaber det en situation, og ikke mindst hvordan interagerer det med betragteren?...

  20. Renal sodium handling and sodium sensitivity

    Directory of Open Access Journals (Sweden)

    Alissa A. Frame

    2017-06-01

    Full Text Available The pathophysiology of hypertension, which affects over 1 billion individuals worldwide, involves the integration of the actions of multiple organ systems, including the kidney. The kidney, which governs sodium excretion via several mechanisms including pressure natriuresis and the actions of renal sodium transporters, is central to long term blood pressure regulation and the salt sensitivity of blood pressure. The impact of renal sodium handling and the salt sensitivity of blood pressure in health and hypertension is a critical public health issue owing to the excess of dietary salt consumed globally and the significant percentage of the global population exhibiting salt sensitivity. This review highlights recent advances that have provided new insight into the renal handling of sodium and the salt sensitivity of blood pressure, with a focus on genetic, inflammatory, dietary, sympathetic nervous system and oxidative stress mechanisms that influence renal sodium excretion. Increased understanding of the multiple integrated mechanisms that regulate the renal handling of sodium and the salt sensitivity of blood pressure has the potential to identify novel therapeutic targets and refine dietary guidelines designed to treat and prevent hypertension.

  1. The handling of chemical data

    CERN Document Server

    Lark, P D; Bosworth, R C L

    1968-01-01

    The Handling of Chemical Data deals with how measurements, such as those arrived at from chemical experimentation, are handled. The book discusses the different kinds of measurements and their specific dimensional characteristics by starting with the origin and presentation of chemical data. The text explains the units, fixed points, and relationships found between scales, the concept of dimensions, the presentation of quantitative data (whether in a tabular or graphical form), and some uses of empirical equations. The book also explains the relationship between two variables, and how equatio

  2. How Retailers Handle Complaint Management

    DEFF Research Database (Denmark)

    Hansen, Torben; Wilke, Ricky; Zaichkowsky, Judy

    2009-01-01

    as to the links between CM and redress of consumers’ complaints. The results suggest that retailers who attach large negative consequences to consumer dissatisfaction are more likely than other retailers to develop a positive strategic view on customer complaining, but at the same time an increase in perceived......This article fills a gap in the literature by providing insight about the handling of complaint management (CM) across a large cross section of retailers in the grocery, furniture, electronic and auto sectors. Determinants of retailers’ CM handling are investigated and insight is gained...... negative consequences of customer dissatisfaction leads to a more negative view on interacting with complaining customers....

  3. Force transmission in offset broach handles used for hip replacement: comparison of three different designs.

    Science.gov (United States)

    Putzer, David; Mayr, Eckart; Haid, Christian; Hozack, Wiliam; Nogler, Michael

    2013-01-01

    In minimally invasive hip arthroplasty double offset broach handles are used, to facilitate the preparation of the femoral canal. The aim of this study was to quantify the differences in force and impulse transmission between two double offset broach handles and a single offset broach handle. Two double offset broach handles (A European version, B American version) were compared to a single offset broach handle. A surgical hammer was used to give a variable impact to the head of the broach handle. Thirty measurements for each of five falling heights were recorded for each broach handle. The force measured by a load cell connected to the broaches was used to obtain the maximum force peak and to calculate the impaction impulse. Normal data distribution was assumed and analysis of variances was performed. Results have demonstrated that the highest values of the force peak and force impulse were found in the single offset broach handle. Broach handle A had higher impulse values and lower maximum force values compared to broach handle B. The lateral lever arm has a measurable effect on the force transmission. In double offset broach handles less energy is transmitted to the tip. Surgeons have to be aware of the differences between the broach handles when using them intraoperatively.

  4. FUEL HANDLING FACILITY CRITICALITY SAFETY CALCULATIONS

    Energy Technology Data Exchange (ETDEWEB)

    C.E. Sanders

    2005-06-30

    The purpose of this design calculation is to perform a criticality evaluation of the Fuel Handling Facility (FHF) and the operations and processes performed therein. The current intent of the FHF is to receive transportation casks whose contents will be unloaded and transferred to waste packages (WP) or MGR Specific Casks (MSC) in the fuel transfer bays. Further, the WPs will also be prepared in the FHF for transfer to the sub-surface facility (for disposal). The MSCs will be transferred to the Aging Facility for storage. The criticality evaluation of the FHF features the following: (I) Consider the types of waste to be received in the FHF as specified below: (1) Uncanistered commercial spent nuclear fuel (CSNF); (2) Canistered CSNF (with the exception of horizontal dual-purpose canister (DPC) and/or multi-purpose canisters (MPCs)); (3) Navy canistered SNF (long and short); (4) Department of Energy (DOE) canistered high-level waste (HLW); and (5) DOE canistered SNF (with the exception of MCOs). (II) Evaluate the criticality analyses previously performed for the existing Nuclear Regulatory Commission (NRC)-certified transportation casks (under 10 CFR 71) to be received in the FHF to ensure that these analyses address all FHF conditions including normal operations, and Category 1 and 2 event sequences. (III) Evaluate FHF criticality conditions resulting from various Category 1 and 2 event sequences. Note that there are currently no Category 1 and 2 event sequences identified for FHF. Consequently, potential hazards from a criticality point of view will be considered as identified in the ''Internal Hazards Analysis for License Application'' document (BSC 2004c, Section 6.6.4). (IV) Assess effects of potential moderator intrusion into the fuel transfer bay for defense in depth. The SNF/HLW waste transfer activity (i.e., assembly and canister transfer) that is being carried out in the FHF has been classified as safety category in the &apos

  5. 21 CFR 820.140 - Handling.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Handling. 820.140 Section 820.140 Food and Drugs... QUALITY SYSTEM REGULATION Handling, Storage, Distribution, and Installation § 820.140 Handling. Each..., contamination, or other adverse effects to product do not occur during handling. ...

  6. 7 CFR 58.443 - Whey handling.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 3 2010-01-01 2010-01-01 false Whey handling. 58.443 Section 58.443 Agriculture... Procedures § 58.443 Whey handling. (a) Adequate sanitary facilities shall be provided for the handling of... objectionable odors. (b) Whey or whey products intended for human food shall at all times be handled in a...

  7. Seven Ways to Handle Pressure

    Institute of Scientific and Technical Information of China (English)

    李冬

    2007-01-01

    1.Take care of your body.Exercise, eat healthily,and get plenty of sleep.You’ll handle stress much better. 2.Take down your thoughts.Recording your thoughts in a diary will help you choose your feelings and relieve~* stress. 3.Talk about it.If possible,find someone

  8. The Dφ Data Handling System

    Institute of Scientific and Technical Information of China (English)

    V.White; D.Adams; 等

    2001-01-01

    In this paper we highlight strategies and choices that make the Dφ Data Handling system markedly different from many other experiments' systems,We emphasize how far the Dφ system has come in innovating and implementing a Dφ-specific Data Grid system.We discuss experiences during the first months of detector commissioning and give some future plans for the system.

  9. Handling nu eller skru ned

    DEFF Research Database (Denmark)

    Kjærsgaard, Poul Søren

    2007-01-01

    Søgningen til fremmedsprogstudier er faldende, samtidig med at Region Syddanmark har lanceret en plan, der forudsætter et sprogligt beredskab. Hvis regionen skal klare sig i konkurrencen, må den og det regionale universitet handle, så at der er sproguddannelser. Ellers må regionen og universitetet...

  10. Data Handling and Parameter Estimation

    DEFF Research Database (Denmark)

    Sin, Gürkan; Gernaey, Krist

    2016-01-01

    literature that are mostly based on the ActivatedSludge Model (ASM) framework and their appropriate extensions (Henze et al., 2000).The chapter presents an overview of the most commonly used methods in the estimation of parameters from experimental batch data, namely: (i) data handling and validation, (ii...

  11. At skabe handling og forandring

    DEFF Research Database (Denmark)

    2015-01-01

    ” (Investigation-Vision-Action-Change, på dansk Undersøgelse-Vision-Handling-Forandring). Forskning i anvendelsen af IVAC i pædagogiske udviklingsprojekter i skoler viser, at lærere kan tilpasse IVAC det konkrete sundhedsemne, de beskæftiger sig med, ligesom metoden kan afpasses pensumkravene, klassetrin og...

  12. TNO reticle handling test platform

    NARCIS (Netherlands)

    Crowcombe, W.E.; Hollemans, C.L.; Fritz, E.C.; Donck, J.C.J. van der; Koster, N.B.

    2014-01-01

    Particle free handling of EUV reticles is a major concern in industry. For reaching economically feasible yield levels, it is reported that Particle-per-Reticle-Pass (PRP) levels should be better than 0.0001 for particles larger than 18 nm. Such cleanliness levels are yet to be reported for current

  13. Remote handling systems for the Pride application

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2010-10-15

    In this paper is described the development of remote handling systems for use in the pyro processing technology development. Remote handling systems mainly include a BDSM (Bridge transported Dual arm Servo-Manipulator) and a simulator, all of which will be applied to the Pride (Pyro process integrated inactive demonstration facility) that is under construction at KAERI. BDMS that will traverse the length of the ceiling is designed to have two pairs of master-slave manipulators of which each pair of master-slave manipulators has a kinematic similarity and a force reflection. A simulator is also designed to provide an efficient means for simulating and verifying the conceptual design, developments, arrangements, and rehearsal of the pyro processing equipment and relevant devices from the viewpoint of remote operation and maintenance. In our research is presented activities and progress made in developing remote handling systems to be used for the remote operation and maintenance of the pyro processing equipment and relevant devices in the Pride. (Author)

  14. Discharging Part of LNG Liquid Cargo Handling Simulator

    Directory of Open Access Journals (Sweden)

    Zhen-Zhou Yang

    2013-09-01

    Full Text Available With the development of the national economy, it is important to develop LNG (Liquefied Natural Gas liquid cargo handling simulator. In this paper, the discharging part of Liquid Cargo Handling Simulator of LNG Carriers is developed by Visual Basic. The system includes 5 major forms and 3 mathematical models such as cargo pump model, the pressure and temperature model of the LNG vapour in the cargo tank and the liquid level model. The system can complete the unloading task. The system has become a preliminary model of LNG liquid cargo handlings simulator training.

  15. Development of Safe Food Handling Guidelines for Korean Consumers.

    Science.gov (United States)

    Kang, Hee-Jin; Lee, Min-Woo; Hwang, In-Kyeong; Kim, Jeong-Weon

    2015-08-01

    The purpose of this study was to develop guidelines for Korean consumers with regard to safe food handling practices at home by identifying current food handling issues. Korean consumers' behaviors regarding their safe food handling were identified via survey questionnaires that included items on individual hygiene practices, prepreparation steps when cooking, the cooking process, and the storage of leftover foods. The subjects were 417 Korean parents with elementary school children living in Seoul and Gyeonggi Province in the central area of Korea. The survey results revealed gaps between the knowledge or practices of Korean consumers and scientific evidence pertaining to safe food handling practices. Based on these findings, a leaflet on safe food handling guidelines was developed in accordance with Korean food culture. These guidelines suggest personal hygiene practices as well as fundamental principles and procedures for safe food handling from the stage of food purchase to that of keeping leftover dishes. A pilot application study with 50 consumers revealed that the guidelines effectively improved Korean consumers' safe food handling practices, suggesting that they can serve as practical educational material suitable for Korean consumers.

  16. Preparing Your Child for Surgery

    Science.gov (United States)

    ... Child What Kids Say About: Handling Stress Anxiety, Fears, and Phobias Community Service: A Family's Guide to Getting Involved Teaching Kids to Be Smart About Social Media Preparing Your Child for Surgery ... Questions Explain the Problem Handle Fears Relieve Guilt Explaining What Will Happen Pre-Operative ...

  17. Handling Software Faults with Redundancy

    Science.gov (United States)

    Carzaniga, Antonio; Gorla, Alessandra; Pezzè, Mauro

    Software engineering methods can increase the dependability of software systems, and yet some faults escape even the most rigorous and methodical development process. Therefore, to guarantee high levels of reliability in the presence of faults, software systems must be designed to reduce the impact of the failures caused by such faults, for example by deploying techniques to detect and compensate for erroneous runtime conditions. In this chapter, we focus on software techniques to handle software faults, and we survey several such techniques developed in the area of fault tolerance and more recently in the area of autonomic computing. Since practically all techniques exploit some form of redundancy, we consider the impact of redundancy on the software architecture, and we propose a taxonomy centered on the nature and use of redundancy in software systems. The primary utility of this taxonomy is to classify and compare techniques to handle software faults.

  18. Enteral Feeding Set Handling Techniques.

    Science.gov (United States)

    Lyman, Beth; Williams, Maria; Sollazzo, Janet; Hayden, Ashley; Hensley, Pam; Dai, Hongying; Roberts, Cristine

    2017-04-01

    Enteral nutrition therapy is common practice in pediatric clinical settings. Often patients will receive a pump-assisted bolus feeding over 30 minutes several times per day using the same enteral feeding set (EFS). This study aims to determine the safest and most efficacious way to handle the EFS between feedings. Three EFS handling techniques were compared through simulation for bacterial growth, nursing time, and supply costs: (1) rinsing the EFS with sterile water after each feeding, (2) refrigerating the EFS between feedings, and (3) using a ready-to-hang (RTH) product maintained at room temperature. Cultures were obtained at baseline, hour 12, and hour 21 of the 24-hour cycle. A time-in-motion analysis was conducted and reported in average number of seconds to complete each procedure. Supply costs were inventoried for 1 month comparing the actual usage to our estimated usage. Of 1080 cultures obtained, the overall bacterial growth rate was 8.7%. The rinse and refrigeration techniques displayed similar bacterial growth (11.4% vs 10.3%, P = .63). The RTH technique displayed the least bacterial growth of any method (4.4%, P = .002). The time analysis in minutes showed the rinse method was the most time-consuming (44.8 ± 2.7) vs refrigeration (35.8 ± 2.6) and RTH (31.08 ± 0.6) ( P < .0001). All 3 EFS handling techniques displayed low bacterial growth. RTH was superior in bacterial growth, nursing time, and supply costs. Since not all pediatric formulas are available in RTH, we conclude that refrigerating the EFS between uses is the next most efficacious method for handling the EFS between bolus feeds.

  19. Remote-Handled Low-Level Waste (RHLLW) Disposal Project Code of Record

    Energy Technology Data Exchange (ETDEWEB)

    S.L. Austad, P.E.; L.E. Guillen, P.E.; C. W. McKnight, P.E.; D. S. Ferguson, P.E.

    2010-10-01

    The Remote-Handled Low-Level Waste Disposal Project addresses an anticipated shortfall in remote-handled LLW disposal capability following cessation of operations at the existing facility, which will continue until it is full or until it must be closed in preparation for final remediation of the Subsurface Disposal Area (approximately at the end of fiscal year 2015). Development of a new onsite disposal facility, the highest ranked alternative, will provide necessary remote handled LLW disposal capability and will ensure continuity of operations that generate remote-handled LLW. This report documents the Code of Record for design of a new LLW disposal capability.

  20. Waste Handling Equipment Devleopment Test and Evaluation

    Energy Technology Data Exchange (ETDEWEB)

    R.L. Tome

    1998-12-01

    The purpose of this study is to identify candidate Monitored Geologic Repository (MGR) surface waste handling equipment for development testing. This study will also identify strategies for performing the development tests. Development testing shall be implemented to support detail design and reduce design risks. Development testing shall be conducted to confirm design concepts, evaluate alternative design concepts, show the availability of needed technology, and provide design documentation. The candidate equipment will be selected from MGR surface waste handling equipment that is the responsibility of the Management and Operating Contractor (M&O) Surface Design Department. The equipment identified in this study is based on Viability Assessment (VA) design. The ''Monitored Geologic Repository Test and Evaluation Plan'' (MGR T&EP), Reference 5.1, was used as a basis for this study. The MGR T&EP reflects the extent of test planning and analysis that can be conducted, given the current status of the MGR requirements and latest VA design information. The MGR T&EP supports the appropriate sections in the license application (LA) in accordance with 10 CFR 60.2 1(c)(14). The MGR T&EP describes the following test activities: site characterization to confirm, by test and analysis, the suitability of the Yucca Mountain site for housing a geologic repository; development testing to investigate and document design concepts to reduce risk; qualification testing to verify equipment compliance with design requirements, specifications, and regulatory requirements; system testing to validate compliance with MGR requirements, which include the receipt, handling, retrieval, and disposal of waste; periodic performance testing to verify preclosure requirements and to demonstrate safe and reliable MGR operation; and performance confirmation modeling, testing, and analysis to verify adherence to postclosure regulatory requirements. Development test activities can be

  1. Factors influencing aircraft ground handling performance

    Science.gov (United States)

    Yager, T. J.

    1983-01-01

    Problems associated with aircraft ground handling operations on wet runways are discussed and major factors which influence tire/runway braking and cornering traction capability are identified including runway characteristics, tire hydroplaning, brake system anomalies, and pilot inputs. Research results from tests with instrumented ground vehicles and aircraft, and aircraft wet runway accident investigation are summarized to indicate the effects of different aircraft, tire, and runway parameters. Several promising means are described for improving tire/runway water drainage capability, brake system efficiency, and pilot training to help optimize aircraft traction performance on wet runways.

  2. Orion Entry Handling Qualities Assessments

    Science.gov (United States)

    Bihari, B.; Tiggers, M.; Strahan, A.; Gonzalez, R.; Sullivan, K.; Stephens, J. P.; Hart, J.; Law, H., III; Bilimoria, K.; Bailey, R.

    2011-01-01

    The Orion Command Module (CM) is a capsule designed to bring crew back from the International Space Station (ISS), the moon and beyond. The atmospheric entry portion of the flight is deigned to be flown in autopilot mode for nominal situations. However, there exists the possibility for the crew to take over manual control in off-nominal situations. In these instances, the spacecraft must meet specific handling qualities criteria. To address these criteria two separate assessments of the Orion CM s entry Handling Qualities (HQ) were conducted at NASA s Johnson Space Center (JSC) using the Cooper-Harper scale (Cooper & Harper, 1969). These assessments were conducted in the summers of 2008 and 2010 using the Advanced NASA Technology Architecture for Exploration Studies (ANTARES) six degree of freedom, high fidelity Guidance, Navigation, and Control (GN&C) simulation. This paper will address the specifics of the handling qualities criteria, the vehicle configuration, the scenarios flown, the simulation background and setup, crew interfaces and displays, piloting techniques, ratings and crew comments, pre- and post-fight briefings, lessons learned and changes made to improve the overall system performance. The data collection tools, methods, data reduction and output reports will also be discussed. The objective of the 2008 entry HQ assessment was to evaluate the handling qualities of the CM during a lunar skip return. A lunar skip entry case was selected because it was considered the most demanding of all bank control scenarios. Even though skip entry is not planned to be flown manually, it was hypothesized that if a pilot could fly the harder skip entry case, then they could also fly a simpler loads managed or ballistic (constant bank rate command) entry scenario. In addition, with the evaluation set-up of multiple tasks within the entry case, handling qualities ratings collected in the evaluation could be used to assess other scenarios such as the constant bank angle

  3. Neonatal handling: an overview of the positive and negative effects.

    Science.gov (United States)

    Raineki, Charlis; Lucion, Aldo B; Weinberg, Joanne

    2014-12-01

    As one of the first rodent models designed to investigate the effects of early-life experiences, the neonatal handling paradigm has helped us better understand how subtle changes in the infant environment can powerfully drive neurodevelopment of the immature brain in typical or atypical trajectories. Here, we review data from more than 50 years demonstrating the compelling effects of neonatal handling on behavior, physiology, and neural function across the lifespan. Moreover, we present data that challenge the classical view of neonatal handling as an animal model that results only in positive/beneficial outcomes. Indeed, the overall goal of this review is to offer the suggestion that the effects of early-life experiences-including neonatal handling-are nuanced rather than unidirectional. Both beneficial and negative outcomes may occur, depending on the parameters of testing, sex of the subject, and neurobehavioral system analyzed. © 2014 Wiley Periodicals, Inc.

  4. Interim report spent nuclear fuel retrieval system fuel handling development testing

    Energy Technology Data Exchange (ETDEWEB)

    Ketner, G.L.; Meeuwsen, P.V.; Potter, J.D.; Smalley, J.T.; Baker, C.P.; Jaquish, W.R.

    1997-06-01

    Fuel handling development testing was performed in support of the Fuel Retrieval System (FRS) Sub-Project at the Hanford Site. The project will retrieve spent nuclear fuel, clean and remove fuel from canisters, repackage fuel into baskets, and load fuel into a multi-canister overpack (MCO) for vacuum drying and interim dry storage. The FRS is required to retrieve basin fuel canisters, clean fuel elements sufficiently of uranium corrosion products (or sludge), empty fuel from canisters, sort debris and scrap from whole elements, and repackage fuel in baskets in preparation for MCO loading. The purpose of fuel handling development testing was to examine the systems ability to accomplish mission activities, optimization of equipment layouts for initial process definition, identification of special needs/tools, verification of required design changes to support performance specification development, and validation of estimated activity times/throughput. The test program was set up to accomplish this purpose through cold development testing using simulated and prototype equipment; cold demonstration testing using vendor expertise and systems; and graphical computer modeling to confirm feasibility and throughput. To test the fuel handling process, a test mockup that represented the process table was fabricated and installed. The test mockup included a Schilling HV series manipulator that was prototypic of the Schilling Hydra manipulator. The process table mockup included the tipping station, sorting area, disassembly and inspection zones, fuel staging areas, and basket loading stations. The test results clearly indicate that the Schilling Hydra arm cannot effectively perform the fuel handling tasks required unless it is attached to some device that can impart vertical translation, azimuth rotation, and X-Y translation. Other test results indicate the importance of camera locations and capabilities, and of the jaw and end effector tool design. 5 refs., 35 figs., 3 tabs.

  5. Orion Handling Qualities During ISS Proximity Operations and Docking

    Science.gov (United States)

    Stephens, John-Paul; Vos, Gordon A.; Bilimoria, Karl D.; Mueller, Eric R.; Brazzel, Jack; Spehar, Pete

    2011-01-01

    NASA's Orion spacecraft is designed to autonomously rendezvous and dock with many vehicles including the International Space Station. However, the crew is able to assume manual control of the vehicle s attitude and flight path. In these instances, Orion must meet handling qualities requirements established by NASA. Two handling qualities assessments were conducted at the Johnson Space Center to evaluate preliminary designs of the vehicle using a six degree of freedom, high-fidelity guidance, navigation, and control simulation. The first assessed Orion s handling qualities during the last 20 ft before docking, and included both steady and oscillatory motions of the docking target. The second focused on manual acquisition of the docking axis during the proximity operations phase and subsequent station-keeping. Cooper-Harper handling qualities ratings, workload ratings and comments were provided by 10 evaluation pilots for the docking study and 5 evaluation pilots for the proximity operations study. For the docking task, both cases received 90% Level 1 (satisfactory) handling qualities ratings, exceeding NASA s requirement. All ratings for the ProxOps task were Level 1. These evaluations indicate that Orion is on course to meet NASA's handling quality requirements for ProxOps and docking.

  6. 7 CFR 1207.307 - Handle.

    Science.gov (United States)

    2010-01-01

    ... Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING AGREEMENTS AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE POTATO RESEARCH AND PROMOTION PLAN Potato Research and Promotion Plan Definitions § 1207.307 Handle. Handle means to grade, pack,...

  7. Proper Handling and Storage of Human Milk

    Science.gov (United States)

    ... Breastfeeding Micronutrient Malnutrition State and Local Programs Proper Handling and Storage of Human Milk Recommend on Facebook ... sure to wash your hands before expressing or handling breast milk. When collecting milk, be sure to ...

  8. 7 CFR 1205.312 - Handle.

    Science.gov (United States)

    2010-01-01

    ... AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE COTTON RESEARCH AND PROMOTION Cotton Research and Promotion Order Definitions § 1205.312 Handle. Handle means to harvest, gin, warehouse, compress, purchase, market, transport, or otherwise acquire ownership or control of cotton....

  9. HMSRP Hawaiian Monk Seal Handling Data

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This data set contains records for all handling and measurement of Hawaiian monk seals since 1981. Live seals are handled and measured during a variety of events...

  10. 7 CFR 983.14 - Handle.

    Science.gov (United States)

    2010-01-01

    ... NEW MEXICO Definitions § 983.14 Handle. Handle means to engage in: (a) Receiving pistachios; (b... of interstate or foreign commerce; and/or (d) Placing pistachios into the current of commerce...

  11. The Department of Energy`s Rocky Flats Plant: A guide to record series useful for health related research. Volume 4: Production and materials handling

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-08-01

    This is the fourth in a series of seven volumes which constitute a guide to records of the Rocky Flats Plant useful for conducting health-related research. The primary purpose of Volume 4 is to describe record series pertaining to production and materials handling activities at the Department of Energy`s (DOE) Rocky Flats Plant, now named the Rocky Flats Environmental Technology Site, near Denver, Colorado. History Associates Incorporated (HAI) prepared this guide as part of its work as the support services contractor for DOE`s Epidemiologic Records Inventory Project. This introduction briefly describes the Epidemiologic Records Inventory Project and HAI`s role in the project, provides a history of production and materials handling practices at Rocky Flats, and identifies organizations contributing to production and materials handling policies and activities. Other topics include the scope and arrangement of the guide and the organization to contact for access to these records.

  12. Logik, mening, handling og tale

    DEFF Research Database (Denmark)

    Widell, Peter

    2009-01-01

    skal ses i relation til sandheds- og meningstilskrivning, sådan som den finder sted ikke i først og fremmest i sproget, men i tanken, sådan som den åbenbarer sig i instrumentelle handling. Det er på baggrund af denne pragmatisering af logikken, talehandlingsbegrebet skal ses: Først og fremmest som den...... instrumentelle handleverdens møde med den sociale verden i assertivet. Dernæst som assertivets nødvendige udspaltninger i normativet og konstativet. Og endelig som de perlokutionære handlinger kommissiv, direktiv og informativ....

  13. 29 CFR 1926.953 - Material handling.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 8 2010-07-01 2010-07-01 false Material handling. 1926.953 Section 1926.953 Labor... Material handling. (a) Unloading. Prior to unloading steel, poles, cross arms and similar material, the... employees exist tag lines or other suitable devices shall be used to control loads being handled by hoisting...

  14. 50 CFR 14.111 - Handling.

    Science.gov (United States)

    2010-10-01

    ... 50 Wildlife and Fisheries 1 2010-10-01 2010-10-01 false Handling. 14.111 Section 14.111 Wildlife and Fisheries UNITED STATES FISH AND WILDLIFE SERVICE, DEPARTMENT OF THE INTERIOR TAKING, POSSESSION... and Birds to the United States § 14.111 Handling. (a) Care shall be exercised to avoid handling the...

  15. 9 CFR 3.118 - Handling.

    Science.gov (United States)

    2010-01-01

    ... 9 Animals and Animal Products 1 2010-01-01 2010-01-01 false Handling. 3.118 Section 3.118 Animals... WELFARE STANDARDS Specifications for the Humane Handling, Care, Treatment, and Transportation of Marine Mammals Transportation Standards § 3.118 Handling. (a) Carriers and intermediate handlers moving marine...

  16. 7 CFR 985.152 - Handling report.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 8 2010-01-01 2010-01-01 false Handling report. 985.152 Section 985.152 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements... HANDLING OF SPEARMINT OIL PRODUCED IN THE FAR WEST Administrative Rules and Regulations § 985.152 Handling...

  17. 9 CFR 3.142 - Handling.

    Science.gov (United States)

    2010-01-01

    ... 9 Animals and Animal Products 1 2010-01-01 2010-01-01 false Handling. 3.142 Section 3.142 Animals... WELFARE STANDARDS Specifications for the Humane Handling, Care, Treatment, and Transportation of... Mammals Transportation Standards § 3.142 Handling. (a) Carriers and intermediate handlers shall move live...

  18. Scheduling of outbound luggage handling at airports

    DEFF Research Database (Denmark)

    Barth, Torben C.; Pisinger, David

    2012-01-01

    This article considers the outbound luggage handling problem at airports. The problem is to assign handling facilities to outbound flights and decide about the handling start time. This dynamic, near real-time assignment problem is part of the daily airport operations. Quality, efficiency and rob...

  19. Overview on Hydrate Coring, Handling and Analysis

    Energy Technology Data Exchange (ETDEWEB)

    Jon Burger; Deepak Gupta; Patrick Jacobs; John Shillinglaw

    2003-06-30

    Gas hydrates are crystalline, ice-like compounds of gas and water molecules that are formed under certain thermodynamic conditions. Hydrate deposits occur naturally within ocean sediments just below the sea floor at temperatures and pressures existing below about 500 meters water depth. Gas hydrate is also stable in conjunction with the permafrost in the Arctic. Most marine gas hydrate is formed of microbially generated gas. It binds huge amounts of methane into the sediments. Worldwide, gas hydrate is estimated to hold about 1016 kg of organic carbon in the form of methane (Kvenvolden et al., 1993). Gas hydrate is one of the fossil fuel resources that is yet untapped, but may play a major role in meeting the energy challenge of this century. In June 2002, Westport Technology Center was requested by the Department of Energy (DOE) to prepare a ''Best Practices Manual on Gas Hydrate Coring, Handling and Analysis'' under Award No. DE-FC26-02NT41327. The scope of the task was specifically targeted for coring sediments with hydrates in Alaska, the Gulf of Mexico (GOM) and from the present Ocean Drilling Program (ODP) drillship. The specific subjects under this scope were defined in 3 stages as follows: Stage 1: Collect information on coring sediments with hydrates, core handling, core preservation, sample transportation, analysis of the core, and long term preservation. Stage 2: Provide copies of the first draft to a list of experts and stakeholders designated by DOE. Stage 3: Produce a second draft of the manual with benefit of input from external review for delivery. The manual provides an overview of existing information available in the published literature and reports on coring, analysis, preservation and transport of gas hydrates for laboratory analysis as of June 2003. The manual was delivered as draft version 3 to the DOE Project Manager for distribution in July 2003. This Final Report is provided for records purposes.

  20. Safety Enhancements for TRU Waste Handling - 12258

    Energy Technology Data Exchange (ETDEWEB)

    Cannon, Curt N. [Perma-Fix Northwest Richland, Inc., Richland, WA 99354 (United States)

    2012-07-01

    For years, proper Health Physics practices and 'As Low As Reasonably Achievable' (ALARA) principles have fostered the use of glove boxes or other methods of handling (without direct contact) high activities of radioactive material. The physical limitations of using glove boxes on certain containers have resulted in high-activity wastes being held in storage awaiting a path forward. Highly contaminated glove boxes and other remote handling equipment no longer in use have also been added to the growing list of items held for storage with no efficient method of preparation for proper disposal without creating exposure risks to personnel. This is especially true for wastes containing alpha-emitting radionuclides such as Plutonium and Americium that pose significant health risks to personnel if these Transuranic (TRU) wastes are not controlled effectively. Like any good safety program or root cause investigation PFNW has found that the identification of the cause of a negative change, if stopped, can result in a near miss and lessons learned. If this is done in the world of safety, it is considered a success story and is to be shared with others to protect the workers. PFNW believes that the tools, equipment and resources have improved over the past number of years but that the use of them has not progressed at the same rate. If we use our tools to timely identify the effect on the work environment and immediately following or possibly even simultaneously identify the cause or some of the causal factors, we may have the ability to continue to work rather than succumb to the start and stop-work mentality trap that is not beneficial in waste minimization, production efficiency or ALARA. (authors)

  1. The effect of handling and training on measures of affective state of farmed mink (Neovison vison)

    DEFF Research Database (Denmark)

    Svendsen, Pernille Maj

    2012-01-01

    The present study aimed to examine if handling and training female mink on a learning task, as preparation for a cognitive bias test, had an effect on measures of their affective state. Adult female farm mink were used based on measures of approach/avoidance behaviour, and categorised as explorat......The present study aimed to examine if handling and training female mink on a learning task, as preparation for a cognitive bias test, had an effect on measures of their affective state. Adult female farm mink were used based on measures of approach/avoidance behaviour, and categorised...... handling and training for the cognitive bias test. Furthermore, the handling and training also had an effect on the E mink, but in the opposite direction. This study showed the preparing mink for a cognitive bias test had a marked effect on measures of their affective state, which has to be considered when...... interpreting the results from experiments using training to assess welfare....

  2. The effect of handle angle on MAWL, wrist posture, RPE, and heart rate.

    Science.gov (United States)

    Wang, M J; Chung, H C; Chen, H C

    2000-01-01

    In manual material handling tasks, the handle serves as the interface between the human operator and the box (the materials). Handle angle design can affect both wrist posture and lifting ability. This study was designed to evaluate the effect of handle angle on maximal acceptable weight of lifting (MAWL), perceived whole-body exertion, whole-body workload, wrist posture, and perceived wrist exertion. The results indicate that handle angle had a significant effect on wrist posture and wrist rating of perceived exertion (RPE). A box with a 0 degrees handle angle induced the greatest ulnar deviation and the highest wrist RPE. A 75 degrees handle angle induced the greatest radial deviation and a relatively high wrist RPE. A 30 degrees handle angle resulted in the greatest MAWL and the lowest level of wrist RPE. Overall, these findings suggest that 30 degrees and 45 degrees handle angles can provide favorable coupling conditions for the cutout-type handhold container handle. Actual or practical applications include the ergonomic design of container handles for manual material handling tasks industry.

  3. THE APPLICATION OF MASSING HANDLING THEORY FOR EVALUATION OF THE APPLICATION OF WHARVES AND LOADING FACILITIES IN THE MARITIME PORT

    Directory of Open Access Journals (Sweden)

    Zbigniew Matuszak

    2016-09-01

    Full Text Available This work presents the general characteristics of the port system. It defines sets and functions describing the structure and work of the port. Moreover, it characterizes foundations of the massive handling theory. It provides basic literature information about selected processes and models of the massive handling theory. On the example of a transportation company serving the loading on ships in the port of Szczecin, it shows the loading method. The material loading onto ships was the sodium water glass. There are observation results of operation times comprising the data available to determine parameters of the massive handling theory. Operations covered in the analysis include: the arrival of the ship at the port’s road, waiting for enter the port, passing through the fairway, waiting for loading, loading, determination of the cargo’s weight, preparation of documents and waiting for leaving the port. It presents critical remarks about possibilities of using the data obtained to describe loading cargo on a ship with the use of elements of the massive handling theory.

  4. MPI Debugging with Handle Introspection

    DEFF Research Database (Denmark)

    Brock-Nannestad, Laust; DelSignore, John; Squyres, Jeffrey M.;

    The Message Passing Interface, MPI, is the standard programming model for high performance computing clusters. However, debugging applications on large scale clusters is difficult. The widely used Message Queue Dumping interface enables inspection of message queue state but there is no general...... interface for extracting information from MPI objects such as communicators. A developer can debug the MPI library as if it was part of the application, but this exposes an unneeded level of detail. The Tools Working Group in the MPI Forum has proposed a specification for MPI Handle Introspection....... It defines a standard interface that lets debuggers extract information from MPI objects. Extracted information is then presented to the developer, in a human readable format. The interface is designed to be independent of MPI implementations and debuggers. In this paper, we describe our support...

  5. Liberalisation of municipal waste handling

    DEFF Research Database (Denmark)

    Busck, Ole Gunni

    2006-01-01

    of price reductions in stead of quality demands in both environmental and working environmental terms. A recent study showed major deficits in the capacities of the municipalities to administer qualitative requirements in the tender process and to manage the contracts as an integral part of a scheme...... for improved performance of municipal waste management. The study stresses the need for training and guidance of municipal administrators. Highlighting ‘best practice’ examples the study shows, however, that it is perfectly possible to end up with quality service on contract. It takes a mixture of careful......Liberalisation of municipal waste handling: How are sustainable practices pursued? In the process of liberalization of public services in Europe contracting out the collection of municipal waste has surged. Research in Denmark has shown that municipalities in general have pursued a narrow policy...

  6. Recent Advances and Future Perspectives on Microfluidic Liquid Handling

    Directory of Open Access Journals (Sweden)

    Nam-Trung Nguyen

    2017-06-01

    Full Text Available The interdisciplinary research field of microfluidics has the potential to revolutionize current technologies that require the handling of a small amount of fluid, a fast response, low costs and automation. Microfluidic platforms that handle small amounts of liquid have been categorised as continuous-flow microfluidics and digital microfluidics. The first part of this paper discusses the recent advances of the two main and opposing applications of liquid handling in continuous-flow microfluidics: mixing and separation. Mixing and separation are essential steps in most lab-on-a-chip platforms, as sample preparation and detection are required for a variety of biological and chemical assays. The second part discusses the various digital microfluidic strategies, based on droplets and liquid marbles, for the manipulation of discrete microdroplets. More advanced digital microfluidic devices combining electrowetting with other techniques are also introduced. The applications of the emerging field of liquid-marble-based digital microfluidics are also highlighted. Finally, future perspectives on microfluidic liquid handling are discussed.

  7. Process Knowledge Summary Report for Materials and Fuels Complex Contact-Handled Transuranic Debris Waste

    Energy Technology Data Exchange (ETDEWEB)

    R. P. Grant; P. J. Crane; S. Butler; M. A. Henry

    2010-02-01

    This Process Knowledge Summary Report summarizes the information collected to satisfy the transportation and waste acceptance requirements for the transfer of transuranic (TRU) waste between the Materials and Fuels Complex (MFC) and the Advanced Mixed Waste Treatment Project (AMWTP). The information collected includes documentation that addresses the requirements for AMWTP and the applicable portion of their Resource Conservation and Recovery Act permits for receipt and treatment of TRU debris waste in AMWTP. This report has been prepared for contact-handled TRU debris waste generated by the Idaho National Laboratory at MFC. The TRU debris waste will be shipped to AMWTP for purposes of supercompaction. This Process Knowledge Summary Report includes information regarding, but not limited to, the generation process, the physical form, radiological characteristics, and chemical contaminants of the TRU debris waste, prohibited items, and packaging configuration. This report, along with the referenced supporting documents, will create a defensible and auditable record for waste originating from MFC.

  8. Ergonomics: safe patient handling and mobility.

    Science.gov (United States)

    Hallmark, Beth; Mechan, Patricia; Shores, Lynne

    2015-03-01

    This article reviews and investigates the issues surrounding ergonomics, with a specific focus on safe patient handling and mobility. The health care worker of today faces many challenges, one of which is related to the safety of patients. Safe patient handling and mobility is on the forefront of the movement to improve patient safety. This article reviews the risks associated with patient handling and mobility, and informs the reader of current evidence-based practice relevant to this area of care.

  9. Enclosure for handling high activity materials

    Energy Technology Data Exchange (ETDEWEB)

    Jimeno de Osso, F.

    1977-07-01

    One of the most important problems that are met at the laboratories producing and handling radioisotopes is that of designing, building and operating enclosures suitable for the safe handling of active substances. With this purpose in mind, an enclosure has been designed and built for handling moderately high activities under a shielding made of 150 mm thick lead. In this report a description is given of those aspects that may be of interest to people working in this field. (Author)

  10. Ergonomic handle for an arthroscopic cutter.

    Science.gov (United States)

    Tuijthof; van Engelen; Herder; Goossens; Snijders; van Dijk

    2003-03-01

    From an analysis of the routinely performed meniscectomy procedures, it was concluded that a punch with a side-ways steerable tip would improve the reachability of meniscal tissue. This potentially leads to a safer and more efficient meniscectomy. Furthermore, the current scissors handles of arthroscopic punches are ergonomically not sufficient. An ergonomic handle is designed with one lever that enables opening and closing of the instrument tip, and side-ways steering of the instrument tip. The design of the handle complies with ergonomic guidelines that were found in the literature. A model of the instrument tip was added to the new handle for comparison with conventional handles. Experiments were performed with a knee joint model, using objective and subjective criteria. The results show that the concept of a side-ways steerable punch is promising, since faster task times are achieved without increasing the risk of damaging healthy tissue. The current design of the ergonomic handle incorporates two degrees of freedom in an intuitive way, the handle is more comfortable to hold, and easy to control. The external memory capabilities of the new handle could be improved. Further development of this handle and the addition of a sufficient instrument tip and force transmission are recommended.

  11. Handling S/MAR vectors.

    Science.gov (United States)

    Hagedorn, Claudia; Baiker, Armin; Postberg, Jan; Ehrhardt, Anja; Lipps, Hans J

    2012-06-01

    Nonviral episomal vectors represent attractive alternatives to currently used virus-based expression systems. In the late 1990s, it was shown that a plasmid containing an expression cassette linked to a scaffold/matrix attached region (S/MAR) replicates as a low copy number episome in all cell lines tested, as well as primary cells, and can be used for the genetic modification of higher animals. Once established in the cell, the S/MAR vector replicates early during S-phase and, in the absence of selection, is stably retained in the cells for an unlimited period of time. This vector can therefore be regarded as a minimal model system for studying the epigenetic regulation of replication and functional nuclear architecture. In theory, this construct represents an almost "ideal" expression system for gene therapy. In practice, S/MAR-based vectors stably modify mammalian cells with efficiencies far below those of virus-based constructs. Consequently, they have not yet found application in gene therapy trials. Furthermore, S/MAR vector systems are not trivial to handle and several critical technical issues have to be considered when modifying these vectors for various applications.

  12. BepiColombo MPO Data Handling and Archiving Operations Strategy

    Science.gov (United States)

    Perez-Lopez, Fernando; Martinez, Santa; de la Fuente, Sara; Lefort, Jayne; Casale, Mauro

    2013-08-01

    This paper describes the BepiColombo MPO Data Handling and Archiving (DHA) Operations Strategy including the justification and the main advantages. This strategy was presented to the MPO Instrument Teams during the BepiColombo Data Handling and Archiving Working Group Meeting #1 held at ESAC in November 2012 and will be implemented by the BepiColombo Science Ground Segment (SGS) in coordination with the MPO Instrument Teams. The paper covers the following topics: BepiColombo Mission Overview, SGS Roles and Interfaces, DHA Strategy Drivers, DHA Strategy Workflow and Conclusions.

  13. The VIRMOS mask manufacturing tools; 2, Mask manufacturing and handling

    CERN Document Server

    Conti, G; Mattaini, E; MacCagni, D; Lefèvre, O; Saisse, M; Vettolani, G

    1999-01-01

    We describe the VIRMOS Mask Manufacturing Unit (MMU) configuration, composed of two units:the Mask Manufacturing Machine (with its Control Unit) and the Mask Handling Unit (inclusive of Control Unit, Storage Cabinets and robot for loading of the Instrument Cabinets). For both VIMOS and NIRMOS instruments, on the basis of orders received by the Mask Preparation Software (see paper (a) in same proceedings), the function of the MMU is to perform an off-line mask cutting and identification, followed by mask storing and subsequent filling of the Instrument Cabinets (IC). We describe the characteristics of the LPKF laser cutting machine and the work done to support the choice of this equipment. We also describe the remaining of the hardware configuration and the Mask Handling Software.

  14. Care and handling of container plants from storage to outplanting

    Science.gov (United States)

    Thomas D. Landis; R. Kasten Dumroese

    2011-01-01

    Nursery plants are in a period of high risk from the time they leave the protected environment of the nursery to when they are outplanted. During handling and shipping, nursery stock may be exposed to many damaging stresses, including extreme temperatures, desiccation, mechanical injuries, and storage molds. This is also the period of greatest financial risk, because...

  15. DNA sequence handling programs in BASIC for home computers.

    OpenAIRE

    Biro, P A

    1984-01-01

    This paper describes a DNA sequence handling program written entirely in BASIC and designed to be run on an Atari home computer. Many of the features common to more sophisticated programs have been included. The advantage of this program are its convenience, its transportability and its potential for user modification. The disadvantages are lack of sophistication and speed.

  16. Handling missing data by re-approaching non-respondents

    NARCIS (Netherlands)

    Huisman, Mark; Krol, B; Van Sonderen, E

    1998-01-01

    When handling missing data, a researcher should be aware of the mechanism underlying the missingness. In the presence of non-randomly missing data, a model of the missing data mechanism should be included in the analyses to prevent the analyses based on the data from becoming biased. Modeling the mi

  17. Prosthetic Hand For Holding Rods, Tools, And Handles

    Science.gov (United States)

    Belcher, Jewell G., Jr.; Vest, Thomas W.

    1995-01-01

    Prosthetic hand with quick-grip/quick-release lever broadens range of specialized functions available to lower-arm amputee by providing improved capabilities for gripping rods, tools, handles, and like. Includes two stationary lower fingers opposed by one pivoting upper finger. Lever operates in conjunction with attached bracket.

  18. A Review of Toxicity and Use and Handling Considerations for Guanidine, Guanidine Hydrochloride, and Urea.

    Energy Technology Data Exchange (ETDEWEB)

    Ertell, Katherine GB

    2006-03-27

    This is a technical report prepared for Oregon Sustainable Energy, LLC, under Agreement 06-19 with PNNL's Office of Small Business Programs. The request was to perform a review of the toxicity and safe handling of guanidine. The request was later amended to add urea. This report summarizes the toxicity data available in the scientific literature and provides an interpretation of the results and recommendations for handling these compounds.

  19. [Nursing workers' perceptions regarding the handling of hazardous chemical waste].

    Science.gov (United States)

    Costa, Taiza Florêncio; Felli, Vanda Elisa Andres; Baptista, Patrícia Campos Pavan

    2012-12-01

    The objectives of this study were to identify the perceptions of nursing workers regarding the handling of hazardous chemical waste at the University of São Paulo University Hospital (HU-USP), and develop a proposal to improve safety measures. This study used a qualitative approach and a convenience sample consisting of eighteen nursing workers. Data collection was performed through focal groups. Thematic analysis revealed four categories that gave evidence of training deficiencies in terms of the stages of handling waste. Difficulties that emerged included a lack of knowledge regarding exposure and its impact, the utilization of personal protective equipment versus collective protection, and suggestions regarding measures to be taken by the institution and workers for the safe handling of hazardous chemical waste. The present data allowed for recommending proposals regarding the safe management of hazardous chemical waste by the nursing staff.

  20. A Versatile Lifting Device for Lunar Surface Payload Handling, Inspection & Regolith Transport Operations

    Science.gov (United States)

    Doggett, William; Dorsey, John; Collins, Tim; King, Bruce; Mikulas, Martin

    2008-01-01

    Devices for lifting and transporting payloads and material are critical for efficient Earth-based construction operations. Devices with similar functionality will be needed to support lunar-outpost construction, servicing, inspection, regolith excavation, grading and payload placement. Past studies have proposed that only a few carefully selected devices are required for a lunar outpost. One particular set of operations involves lifting and manipulating payloads in the 100 kg to 3,000 kg range, which are too large or massive to be handled by unassisted astronauts. This paper will review historical devices used for payload handling in space and on earth to derive a set of desirable features for a device that can be used on planetary surfaces. Next, an innovative concept for a lifting device is introduced, which includes many of the desirable features. The versatility of the device is discussed, including its application to lander unloading, servicing, inspection, regolith excavation and site preparation. Approximate rules, which can be used to size the device for specific payload mass and reach requirements, are provided. Finally, details of a test-bed implementation of the innovative concept, which will be used to validate the structural design and develop operational procedures, is provided.

  1. Evaluating ITER remote handling middleware concepts

    Energy Technology Data Exchange (ETDEWEB)

    Koning, J.F., E-mail: j.f.koning@differ.nl [FOM Institute DIFFER, Association EURATOM-FOM, Partner in the Trilateral Euregio Cluster and ITER-NL, PO Box 1207, 3430 BE Nieuwegein (Netherlands); Heemskerk, C.J.M.; Schoen, P.; Smedinga, D. [Heemskerk Innovative Technology, Noordwijk (Netherlands); Boode, A.H. [University of Applied Sciences InHolland, Alkmaar (Netherlands); Hamilton, D.T. [ITER Organization, Route de Vinon sur Verdon, 13115 Saint Paul Lez Durance (France)

    2013-10-15

    Highlights: ► Remote Handling Study Centre: middleware system setup and modules built. ► Aligning to ITER RH Control System Layout: prototype of database, VR and simulator. ► OpenSplice DDS, ZeroC ICE messaging and object oriented middlewares reviewed. ► Windows network latency found problematic for semi-realtime control over the network. -- Abstract: Remote maintenance activities in ITER will be performed by a unique set of hardware systems, supported by an extensive software kit. A layer of middleware will manage and control a complex set of interconnections between teams of operators, hardware devices in various operating theatres, and databases managing tool and task logistics. The middleware is driven by constraints on amounts and timing of data like real-time control loops, camera images, and database access. The Remote Handling Study Centre (RHSC), located at FOM institute DIFFER, has a 4-operator work cell in an ITER relevant RH Control Room setup which connects to a virtual hot cell back-end. The centre is developing and testing flexible integration of the Control Room components, resulting in proof-of-concept tests of this middleware layer. SW components studied include generic human-machine interface software, a prototype of a RH operations management system, and a distributed virtual reality system supporting multi-screen, multi-actor, and multiple independent views. Real-time rigid body dynamics and contact interaction simulation software supports simulation of structural deformation, “augmented reality” operations and operator training. The paper presents generic requirements and conceptual design of middleware components and Operations Management System in the context of a RH Control Room work cell. The simulation software is analyzed for real-time performance and it is argued that it is critical for middleware to have complete control over the physical network to be able to guarantee bandwidth and latency to the components.

  2. Ergonomic design and evaluation of the handle for an endoscopic dissector.

    Science.gov (United States)

    Shimomura, Yoshihiro; Minowa, Keita; Kawahira, Hiroshi; Katsuura, Tetsuo

    2016-05-01

    The purpose of this study was to design an endoscopic dissector handle and objectively assess its usability. The handles were designed with increased contact area between the fingers and thumb and the eye rings, and the eye rings were modified to have a more perpendicular insertion angle to the finger midline. Four different handle models were compared, including a conventional product. Subjects performed dissection, exclusion, grasping, precision manipulation and precision handling tasks. Electromyography and subjective evaluations were measured. Compared to conventional handles, the designated handle reduced the muscle load in the extensor and flexor muscles of the forearm and increased subjective stability. The activity of the first dorsal interosseous muscle was sometimes influenced by the shape of the other parts. The ergonomically designed endoscopic dissector handle used in this study achieved high usability. Medical instrument designs based on ergonomic concepts should be assessed with objective indices. Practitioner Summary: The endoscopic dissector handles were designed with increased contact area and more suitable insertion angle between the fingers and thumb and the eye rings. Compared to conventional handles, the designated handle reduced the muscle load in the extensor and flexor muscles of the forearm and increased subjective stability.

  3. Research on Event Handling Models of Java

    Institute of Scientific and Technical Information of China (English)

    WU Yue; WU Jing; ZHOU Ming-tian

    2004-01-01

    A new event-handling paradigm and its application model are proposed. The working mechanism and principle of event listener model is given in detail. Finally, the launching event mechanisms,the choosing event handling models and the dispatching mechanism are illustrated.

  4. 9 CFR 3.19 - Handling.

    Science.gov (United States)

    2010-01-01

    ... 9 Animals and Animal Products 1 2010-01-01 2010-01-01 false Handling. 3.19 Section 3.19 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE ANIMAL WELFARE STANDARDS Specifications for the Humane Handling, Care, Treatment, and Transportation of Dogs...

  5. 9 CFR 3.41 - Handling.

    Science.gov (United States)

    2010-01-01

    ... 9 Animals and Animal Products 1 2010-01-01 2010-01-01 false Handling. 3.41 Section 3.41 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE ANIMAL WELFARE STANDARDS Specifications for the Humane Handling, Care, Treatment, and Transportation of...

  6. 9 CFR 3.92 - Handling.

    Science.gov (United States)

    2010-01-01

    ... 9 Animals and Animal Products 1 2010-01-01 2010-01-01 false Handling. 3.92 Section 3.92 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE ANIMAL WELFARE STANDARDS Specifications for the Humane Handling, Care, Treatment, and Transportation of...

  7. 9 CFR 3.66 - Handling.

    Science.gov (United States)

    2010-01-01

    ... 9 Animals and Animal Products 1 2010-01-01 2010-01-01 false Handling. 3.66 Section 3.66 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE ANIMAL WELFARE STANDARDS Specifications for the Humane Handling, Care, Treatment and Transportation of...

  8. 29 CFR 1917.18 - Log handling.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 7 2010-07-01 2010-07-01 false Log handling. 1917.18 Section 1917.18 Labor Regulations...) MARINE TERMINALS Marine Terminal Operations § 1917.18 Log handling. (a) The employer shall ensure that structures (bunks) used to contain logs have rounded corners and rounded structural parts to avoid...

  9. 38 CFR 1.660 - Expeditious handling.

    Science.gov (United States)

    2010-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 1 2010-07-01 2010-07-01 false Expeditious handling. 1.660 Section 1.660 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS GENERAL PROVISIONS Inventions by Employees of Department of Veterans Affairs § 1.660 Expeditious handling. No patent...

  10. 30 CFR 715.16 - Topsoil handling.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 3 2010-07-01 2010-07-01 false Topsoil handling. 715.16 Section 715.16 Mineral Resources OFFICE OF SURFACE MINING RECLAMATION AND ENFORCEMENT, DEPARTMENT OF THE INTERIOR INITIAL PROGRAM REGULATIONS GENERAL PERFORMANCE STANDARDS § 715.16 Topsoil handling. To prevent topsoil from being...

  11. 7 CFR 1219.11 - Handle.

    Science.gov (United States)

    2010-01-01

    ... AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE HASS AVOCADO PROMOTION, RESEARCH, AND INFORMATION Hass Avocado Promotion, Research, and Information Order Definitions § 1219.11 Handle. Handle means to pack, process, transport, purchase, or in any other way to place or cause Hass...

  12. Information Handling, Organizational Structure, and Power.

    Science.gov (United States)

    Buckland, Michael K.

    1989-01-01

    Uses examples from military strategic communications to demonstrate that organizational structures and the distribution of power within organizational structures adapt to changes in information handling capability. It is concluded that delegation and decentralization can be viewed as indicative of inadequate information handling and that improved…

  13. Storage and Handling of Commercially Packaged Foods

    OpenAIRE

    Villalba, Abigail; Boyer, Renee Raiden; Bazemore, Sherry

    2005-01-01

    Proper selection of foods at the grocery store and appropriate storage and handling practices at home are necessary to maintain the quality and safety of commercially processed foods and perishable foods. This brochure offers some guidelines to follow when buying, handling, and storing packaged foods.

  14. Material Handling Equipment Evaluation for Crater Repair

    Science.gov (United States)

    2016-11-01

    material handling equipment with a reduced logistical footprint for use by crater repair teams in airfield damage repair (ADR) scenarios. A market ...compared to currently utilized material handling equipment. This report presents the results of the market survey and equipment evaluations. Results...1 1.2 Objective and scope

  15. Feasibility of Upper Port Plug tube handling

    NARCIS (Netherlands)

    Koning, J.F.; Elzendoorn, B.S.Q.; Ronden, D.M.S.; Klinkhamer, J.F.F.; Biel, W.; Krasikov, Y.; Walker, C.I.

    2011-01-01

    Central, retractable tubes are proposed in several Upper Port Plugs (UPPs) designs for ITER, to enable fast exchange of specific components of diagnostics housed in these UPPs. This paper investigates into possible designs to enable the efficient handling of tubes. The feasibility of tube handling i

  16. 7 CFR 765.151 - Handling payments.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 7 2010-01-01 2010-01-01 false Handling payments. 765.151 Section 765.151 Agriculture Regulations of the Department of Agriculture (Continued) FARM SERVICE AGENCY, DEPARTMENT OF AGRICULTURE SPECIAL PROGRAMS DIRECT LOAN SERVICING-REGULAR Borrower Payments § 765.151 Handling payments. (a) Borrower...

  17. Reducing Mouse Anxiety during Handling: Effect of Experience with Handling Tunnels

    OpenAIRE

    Kelly Gouveia; Hurst, Jane L.

    2013-01-01

    Handling stress is a well-recognised source of variation in animal studies that can also compromise the welfare of research animals. To reduce background variation and maximise welfare, methods that minimise handling stress should be developed and used wherever possible. Recent evidence has shown that handling mice by a familiar tunnel that is present in their home cage can minimise anxiety compared with standard tail handling. As yet, it is unclear whether a tunnel is required in each home c...

  18. Preliminary Hazard Analysis for the Remote-Handled Low-Level Waste Disposal Facility

    Energy Technology Data Exchange (ETDEWEB)

    Lisa Harvego; Mike Lehto

    2010-02-01

    The need for remote handled low level waste (LLW) disposal capability has been identified. A new onsite, remote-handled LLW disposal facility has been identified as the highest ranked alternative for providing continued, uninterrupted remote-handled LLW disposal capability for remote-handled LLW that is generated as part of the nuclear mission of the Idaho National Laboratory and from spent nuclear fuel processing activities at the Naval Reactors Facility. Historically, this type of waste has been disposed of at the Radioactive Waste Management Complex. Disposal of remote-handled LLW in concrete disposal vaults at the Radioactive Waste Management Complex will continue until the facility is full or until it must be closed in preparation for final remediation of the Subsurface Disposal Area (approximately at the end of Fiscal Year 2017). This document supports the conceptual design for the proposed remote-handled LLW disposal facility by providing an initial nuclear facility hazard categorization and by identifying potential hazards for processes associated with onsite handling and disposal of remote-handled LLW.

  19. Preliminary Hazard Analysis for the Remote-Handled Low-Level Waste Disposal Project

    Energy Technology Data Exchange (ETDEWEB)

    Lisa Harvego; Mike Lehto

    2010-10-01

    The need for remote handled low level waste (LLW) disposal capability has been identified. A new onsite, remote-handled LLW disposal facility has been identified as the highest ranked alternative for providing continued, uninterrupted remote-handled LLW disposal capability for remote-handled LLW that is generated as part of the nuclear mission of the Idaho National Laboratory and from spent nuclear fuel processing activities at the Naval Reactors Facility. Historically, this type of waste has been disposed of at the Radioactive Waste Management Complex. Disposal of remote-handled LLW in concrete disposal vaults at the Radioactive Waste Management Complex will continue until the facility is full or until it must be closed in preparation for final remediation of the Subsurface Disposal Area (approximately at the end of Fiscal Year 2017). This document supports the conceptual design for the proposed remote-handled LLW disposal facility by providing an initial nuclear facility hazard categorization and by identifying potential hazards for processes associated with onsite handling and disposal of remote-handled LLW.

  20. Effects of angling and manual handling on pike behaviour investigated by high-resolution positional telemetry

    DEFF Research Database (Denmark)

    Baktoft, Henrik; Aarestrup, Kim; Berg, Søren;

    2013-01-01

    Human disturbances such as angling and manual handling may have long-term effects on the behaviour of pike, Esox lucius L., an ecologically important species. Using continuous high-resolution positional telemetry, this study compared the swimming activity of handled and unhandled pike in a small...... lake. Pike pre-equipped with acoustic transmitters were angled and exposed to a handling protocol including measurements of length and mass. Pike not recaptured constituted an unhandled control group. Results demonstrated that the handling protocol caused temperature-dependent changes in pike activity......, with higher temperatures leading to lower activity of the recaptured pike. The effects, however, were transitory and not detectable after 48-h post-release. These findings indicate that pike are relatively resilient to handling and quickly resume pre-handling activity...

  1. Remote handling assessment of attachment concepts for DEMO blanket segments

    Energy Technology Data Exchange (ETDEWEB)

    Iglesias, Daniel, E-mail: daniel.iglesias@ccfe.ac.uk [CCFE, Culham Science Centre, Abingdon, Oxon OX14 3DB (United Kingdom); Bastow, Roger; Cooper, Dave; Crowe, Robert; Middleton-Gear, Dave [CCFE, Culham Science Centre, Abingdon, Oxon OX14 3DB (United Kingdom); Sibois, Romain [VTT, Technical Research Centre of Finland, Industrial Systems, ROViR, Tampere (Finland); Carloni, Dario [Institute of Neutron Physics and Reactor Technology, Karlsruhe Institute of Technology (KIT) (Germany); Vizvary, Zsolt; Crofts, Oliver [CCFE, Culham Science Centre, Abingdon, Oxon OX14 3DB (United Kingdom); Harman, Jon [EFDA Close Support Unit Garching, Boltzmannstaße 2, D-85748 Garching bei München (Germany); Loving, Antony [CCFE, Culham Science Centre, Abingdon, Oxon OX14 3DB (United Kingdom)

    2015-10-15

    Highlights: • Challenges are identified for the remote handling of blanket segments’ attachments. • Two attachment design approaches are assessed for remote handling (RH) feasibility. • An alternative is proposed, which potentially simplifies and speeds-up RH operations. • Up to three different assemblies are proposed for the remote handling of the attachments. • Proposed integrated design of upper port is compatible with the attachment systems. - Abstract: The replacement strategy of the massive Multi-Module Blanket Segments (MMS) is a key driver in the design of several DEMO systems. These include the blankets themselves, the vacuum vessel (VV) and its ports and the Remote Maintenance System (RMS). Common challenges to any blanket attachment system have been identified, such as the need for applying a preload to the MMS manifold, the effects of the decay heat and several uncertainties related to permanent deformations when removing the blanket segments after service. The WP12 kinematics of the MMS in-vessel transportation was adapted to the requirements of each of the supports during 2013 and 2014 design activities. The RM equipment envisaged for handling attachments and earth connections may be composed of up to three different assemblies. An In-Vessel Mover at the divertor level handles the lower support and earth bonding, and could stabilize the MMS during transportation. A Shield Plug crane with a 6 DoF manipulator operates the upper attachment and earth straps. And a Vertical Maintenance Crane is responsible for the in-vessel MMS transportation and can handle the removable upper support pins. A final proposal is presented which can potentially reduce the number of required systems, at the same time that speeds-up the RMS global operations.

  2. Musculoskeletal injuries resulting from patient handling tasks among hospital workers.

    Science.gov (United States)

    Pompeii, Lisa A; Lipscomb, Hester J; Schoenfisch, Ashley L; Dement, John M

    2009-07-01

    The purpose of this study was to evaluate musculoskeletal injuries and disorders resulting from patient handling prior to the implementation of a "minimal manual lift" policy at a large tertiary care medical center. We sought to define the circumstances surrounding patient handling injuries and to identify potential preventive measures. Human resources data were used to define the cohort and their time at work. Workers' compensation records (1997-2003) were utilized to identify work-related musculoskeletal claims, while the workers' description of injury was used to identify those that resulted from patient handling. Adjusted rate ratios were generated using Poisson regression. One-third (n = 876) of all musculoskeletal injuries resulted from patient handling activities. Most (83%) of the injury burden was incurred by inpatient nurses, nurses' aides and radiology technicians, while injury rates were highest for nurses' aides (8.8/100 full-time equivalent, FTEs) and smaller workgroups including emergency medical technicians (10.3/100 FTEs), patient transporters (4.3/100 FTEs), operating room technicians (3.1/100 FTEs), and morgue technicians (2.2/100 FTEs). Forty percent of injuries due to lifting/transferring patients may have been prevented through the use of mechanical lift equipment, while 32% of injuries resulting from repositioning/turning patients, pulling patients up in bed, or catching falling patients may not have been prevented by the use of lift equipment. The use of mechanical lift equipment could significantly reduce the risk of some patient handling injuries but additional interventions need to be considered that address other patient handling tasks. Smaller high-risk workgroups should not be neglected in prevention efforts.

  3. Displaced Medial and Lateral Bucket Handle Meniscal Tears With Intact ACL and PCL.

    Science.gov (United States)

    Boody, Barrett S; Omar, Imran M; Hill, James A

    2015-08-01

    Bucket handle lesions are vertical longitudinal tears in the meniscus that may displace centrally into the respective medial or lateral compartment, frequently causing mechanical symptoms, including pain, perceived instability, and mechanical locking. Bucket handle meniscal tears are most commonly from a traumatic etiology and are frequently found with concomitant anterior cruciate ligament (ACL) injuries. Multiple imaging signs and associations have been described for the diagnosis of bucket handle meniscus tears, including coronal truncation, absent bow tie sign, double posterior cruciate ligament (PCL), double ACL, displacement of the bucket handle fragment, and disproportionate posterior horn signs. Among meniscal pathology encountered on magnetic resonance imaging or during arthroscopy, bucket handle meniscal tears are infrequent occurrences. Furthermore, the occurrence of displaced medial and lateral bucket handle tears found on imaging and during arthroscopy is very uncommon and is only sparsely reported in the literature. When displaced medial and lateral bucket handle meniscal segments are visualized within the intercondylar notch along with the ACL and PCL, the radiologic findings are referred to as the "quadruple cruciate" sign or the "Jack and Jill lesion." Of the few case reports described in the literature, only one noted displaced medial and lateral bucket handle meniscus tears with an intact ACL and PCL. The current case report outlines a similar rare case of the quadruple cruciate sign: displaced medial and lateral bucket handle meniscal tears located within the intercondylar notch and an intact ACL and PCL.

  4. Impact of biospecimens handling on biomarker research in breast cancer

    Directory of Open Access Journals (Sweden)

    Callari Maurizio

    2009-11-01

    Full Text Available Abstract Background Gene expression profiling is moving from the research setting to the practical clinical use. Gene signatures able to correctly identify high risk breast cancer patients as well as to predict response to treatment are currently under intense investigation. While technical issues dealing with RNA preparation, choice of array platforms, statistical analytical tools are taken into account, the tissue collection process is seldom considered. The time elapsed between surgical tissue removal and freezing of samples for biological characterizations is rarely well defined and/or recorded even for recently stored samples, despite the publications of standard operating procedures for biological sample collection for tissue banks. Methods Breast cancer samples from 11 patients were collected immediately after surgical removal and subdivided into aliquots. One was immediately frozen and the others were maintained at room temperature for respectively 2, 6 and 24 hrs. RNA was extracted and gene expression profile was determined using cDNA arrays. Phosphoprotein profiles were studied in parallel. Results Delayed freezing affected the RNA quality only in 3 samples, which were not subjected to gene profiling. In the 8 breast cancer cases with apparently intact RNA also in sample aliquots frozen at delayed times, 461 genes were modulated simply as a function of freezing timing. Some of these genes were included in gene signatures biologically and clinically relevant for breast cancer. Delayed freezing also affected detection of phosphoproteins, whose pattern may be crucial for clinical decision on target-directed drugs. Conclusion Time elapsed between surgery and freezing of samples appears to have a strong impact and should be considered as a mandatory variable to control for clinical implications of inadequate tissue handling.

  5. Anchor handling tug operations: a practical guide to the operation of modern anchor handling tugs engaged in anchor handling and towing operations

    National Research Council Canada - National Science Library

    Clark, I.C; Hancox, M

    2012-01-01

    ... --Turning and manoeuvring modern anchor handling vessels --The AHTS design and towing operations --The dangers of very high speed loads during deep water anchor handling operations --The dangers...

  6. pypk - A Python extension module to handle chemical kinetics in plasma physics modeling

    Directory of Open Access Journals (Sweden)

    2008-06-01

    Full Text Available PLASMAKIN is a package to handle physical and chemical data used in plasma physics modeling and to compute gas-phase and gas-surface kinetics data: particle production and loss rates, photon emission spectra and energy exchange rates. A large number of species properties and reaction types are supported, namely: gas or electron temperature dependent collision rate coefficients, vibrational and cascade levels, evaluation of branching ratios, superelastic and other reverse processes, three-body collisions, radiation imprisonment and photoelectric emission. Support of non-standard rate coefficient functions can be handled by a user-supplied shared library.

    The main block of the PLASMAKIN package is a Fortran module that can be included in an user's program or compiled as a shared library, libpk. pypk is a new addition to the package and provides access to libpk from Python programs. It is build on top of the ctypes foreign function library module and is prepared to work with several Fortran compilers. However pypk is more than a wrapper and provides its own classes and functions taking advantage of Python language characteristics. Integration with Python tools allows substantial productivity gains on program development and insight on plasma physics problems.

  7. How the NWC handles software as product

    Energy Technology Data Exchange (ETDEWEB)

    Vinson, D.

    1997-11-01

    This tutorial provides a hands-on view of how the Nuclear Weapons Complex project should be handling (or planning to handle) software as a product in response to Engineering Procedure 401099. The SQAS has published the document SQAS96-002, Guidelines for NWC Processes for Handling Software Product, that will be the basis for the tutorial. The primary scope of the tutorial is on software products that result from weapons and weapons-related projects, although the information presented is applicable to many software projects. Processes that involve the exchange, review, or evaluation of software product between or among NWC sites, DOE, and external customers will be described.

  8. Reducing mouse anxiety during handling: effect of experience with handling tunnels.

    Science.gov (United States)

    Gouveia, Kelly; Hurst, Jane L

    2013-01-01

    Handling stress is a well-recognised source of variation in animal studies that can also compromise the welfare of research animals. To reduce background variation and maximise welfare, methods that minimise handling stress should be developed and used wherever possible. Recent evidence has shown that handling mice by a familiar tunnel that is present in their home cage can minimise anxiety compared with standard tail handling. As yet, it is unclear whether a tunnel is required in each home cage to improve response to handling. We investigated the influence of prior experience with home tunnels among two common strains of laboratory mice: ICR(CD-1) and C57BL/6. We compared willingness to approach the handler and anxiety in an elevated plus maze test among mice picked up by the tail, by a home cage tunnel or by an external tunnel shared between cages. Willingness to interact with the handler was much greater for mice handled by a tunnel, even when this was unfamiliar, compared to mice picked up by the tail. Once habituated to handling, C57BL/6 mice were most interactive towards a familiar home tunnel, whereas the ICR strain showed strong interaction with all tunnel handling regardless of any experience of a home cage tunnel. Mice handled by a home cage or external tunnel showed less anxiety in an elevated plus maze than those picked up by the tail. This study shows that using a tunnel for routine handling reduces anxiety among mice compared to tail handling regardless of prior familiarity with tunnels. However, as home cage tunnels can further improve response to handling in some mice, we recommend that mice are handled with a tunnel provided in their home cage where possible as a simple practical method to minimise handling stress.

  9. Yeast responses to stresses associated with industrial brewery handling.

    Science.gov (United States)

    Gibson, Brian R; Lawrence, Stephen J; Leclaire, Jessica P R; Powell, Chris D; Smart, Katherine A

    2007-09-01

    During brewery handling, production strains of yeast must respond to fluctuations in dissolved oxygen concentration, pH, osmolarity, ethanol concentration, nutrient supply and temperature. Fermentation performance of brewing yeast strains is dependent on their ability to adapt to these changes, particularly during batch brewery fermentation which involves the recycling (repitching) of a single yeast culture (slurry) over a number of fermentations (generations). Modern practices, such as the use of high-gravity worts and preparation of dried yeast for use as an inoculum, have increased the magnitude of the stresses to which the cell is subjected. The ability of yeast to respond effectively to these conditions is essential not only for beer production but also for maintaining the fermentation fitness of yeast for use in subsequent fermentations. During brewery handling, cells inhabit a complex environment and our understanding of stress responses under such conditions is limited. The advent of techniques capable of determining genomic and proteomic changes within the cell is likely vastly to improve our knowledge of yeast stress responses during industrial brewery handling.

  10. An exploration of knowledge and practice of patient handling among undergraduate occupational therapy students.

    Science.gov (United States)

    Mc Grath, Margaret; Taaffe, Ciara; Gallagher, Aideen

    2015-01-01

    To explore knowledge and practice relating to patient handling among final year occupational therapy students in the Republic of Ireland. We conducted a survey of final year students in three out of four occupational therapy programs in the Republic of Ireland (n = 81). The survey measured students' knowledge of manual handling principles and techniques and explored their experiences and ability to apply this knowledge to clinical situations. All students (n = 81) had undertaken training in patient handling. Just under half of students (n = 35, 43.2%) had received additional training outside of the university setting. Overall knowledge of safe patient handling principles techniques and risk assessment was low (Mean Score = 15.71/28; SD = 3.81). Participants who received additional training achieved a lower mean total score (M = 13.89, SD = 3.54) than those who only undertook university-based training (M = 18.11; SD = 2.66; t(79) = -5.87; p occupational therapy students in Ireland receive training in safe patient handling they appear to have limited knowledge of best practice and experience difficulties in applying their learning to clinical situations. There is an urgent need to consider the effectiveness of current educational strategies in this area. Implications for Rehabilitation Safe patient handling is a key component in preventing musculoskeletal injury among rehabilitation professionals The extent to which pre-professional training prepares rehabilitation professionals to practice safe patient handling is unclear Occupational therapy students in this study had limited knowledge of safe patient handling and had difficulty applying their learning to clinical practice Alternative education models are required to support development of safe patient handling skills. Educators may wish to consider how safe patient handling can be embedded across curricula to avoid the challenges of once off instruction and massed practice.

  11. Promoting positive states: the effect of early human handling on play and exploratory behaviour in pigs.

    Science.gov (United States)

    Zupan, M; Rehn, T; de Oliveira, D; Keeling, L J

    2016-01-01

    It is known that tactile stimulation (TS) during ontogeny modifies brain plasticity and enhances the motor and cognitive skills. Our hypothesis was that early handling including TS would increase play and exploratory behaviour in commercial pigs under standardized test conditions. Piglets from 13 litters were subjected to three handling treatments from 5 to 35 days of age: all the piglets were handled (H), none of the piglets were handled (NH) or half of the piglets in the litter were handled (50/50). At 42 days of age, the pigs' behaviour was observed in pairs in a novel pen with a 'toy' (tug rope). The main results were that more locomotor play was performed by pigs from litters where all or half of them had been handled, whereas social exploratory behaviour was more pronounced in pigs from litters where half of them had been handled. Although behaviour was affected by the interaction of treatment with sex or with weight category, we propose that the handling procedure does seem to have acted to increase locomotor skills and that handling half of the piglets in the litter may have triggered a series of socio-emotional interactions that were beneficial for the whole group.

  12. Management of transport and handling contracts

    CERN Document Server

    Rühl, I

    2004-01-01

    This paper shall outline the content, application and management strategies for the various contracts related to transport and handling activities. In total, the two sections Logistics and Handling Maintenance are in charge of 27 (!) contracts ranging from small supply contracts to big industrial support contracts. The activities as well as the contracts can generally be divided into four main topics "Vehicle Fleet Management"; "Supply, Installation and Commissioning of Lifting and Hoisting Equipment"; "Equipment Maintenance" and "Industrial Support for Transport and Handling". Each activity and contract requires different approaches and permanent adaptation to the often changing CERN's requirements. In particular, the management and the difficulties experienced with the contracts E072 "Maintenance of lifting and hoisting equipment", F420 "Supply of seven overhead traveling cranes for LHC" and S090/S103 "Industrial support for transport and handling" will be explained in detail.

  13. Handling knowledge on osteoporosis - a qualitative study

    DEFF Research Database (Denmark)

    Nielsen, Dorthe; Huniche, Lotte; Brixen, Kim

    2013-01-01

    Scand J Caring Sci; 2012 Handling knowledge on osteoporosis - a qualitative study The aim of this qualitative study was to increase understanding of the importance of osteoporosis information and knowledge for patients' ways of handling osteoporosis in their everyday lives. Interviews were...... performed with 14 patients recruited from two English university hospitals and 12 patients from a Danish university hospital. Critical psychology was used as a theoretical framework for the data analysis, which aimed at shedding light on patients' ways of conducting everyday life with osteoporosis....... The themes that emerged from the analysis showed that life conditions influenced the way in which risk, pain and osteoporosis were handled. Everyday life was also influenced by patients' attitude to treatment. The patients who were experiencing emotional difficulties in handling osteoporosis were not those...

  14. Live-trapping and handling brown bear

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This paper reports techniques developed to live trap and handle brown bears on the Kodiak National Wildlife Refuge. The brown bears (Ursus middendorffi) on the...

  15. Aerobot Sampling and Handling System Project

    Data.gov (United States)

    National Aeronautics and Space Administration — Honeybee Robotics proposes to: ?Derive and document the functional and technical requirements for Aerobot surface sampling and sample handling across a range of...

  16. 7 CFR 926.9 - Handle.

    Science.gov (United States)

    2010-01-01

    ... the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements and Orders; Fruits, Vegetables, Nuts), DEPARTMENT OF AGRICULTURE DATA COLLECTION, REPORTING AND RECORDKEEPING REQUIREMENTS APPLICABLE TO CRANBERRIES NOT SUBJECT TO THE CRANBERRY MARKETING ORDER § 926.9 Handle....

  17. How Do Search Engines Handle Chinese Queries?

    Directory of Open Access Journals (Sweden)

    Hong Cui

    2005-10-01

    Full Text Available The use of languages other than English has been growing exponentially on the Web. However, the major search engines have been lagging behind in providing indexes and search features to handle these languages. This article explores the characteristics of the Chinese language and how queries in this language are handled by different search engines. Queries were entered in two major search engines (Google and AlltheWeb and two search engines developed for Chinese (Sohu and Baidu. Criteria such as handling word segmentation, number of retrieved documents, and correct display and identification of Chinese characters were used to examine how the search engines handled the queries. The results showed that the performance of the two major search engines was not on a par with that of the search engines developed for Chinese.

  18. GeoLab Sample Handling System Project

    Data.gov (United States)

    National Aeronautics and Space Administration — Develop  a robotic sample handling/ manipulator system for the GeoLab glovebox. This work leverages from earlier GeoLab work and a 2012 collaboration with a...

  19. 30o inclination in handles of plastic boxes can reduce postural and muscular workload during handling

    Directory of Open Access Journals (Sweden)

    Luciana C. C. B. Silva

    2013-06-01

    Full Text Available BACKGROUND: The handling of materials, which occurs in the industrial sector, is associated with lesions on the lumbar spine and in the upper limbs. Inserting handles in industrial boxes is a way to reduce work-related risks. Although the position and angle of the handles are significant factors in comfort and safety during handling, these factors have rarely been studied objectively. OBJECTIVE: To compare the handling of a commercial box and prototypes with handles and to evaluate the effects on upper limb posture, muscle electrical activity, and perceived acceptability using different grips while handling materials from different heights. METHOD: Thirty-seven healthy volunteers evaluated the handles of prototypes that allowed for changes in position (top and bottom and angle (0°, 15°, and 30°. Wrist, elbow, and shoulder movements were evaluated using electrogoniometry and inclinometry. The muscle electrical activity in the wrist extensors, biceps brachii, and the upper portion of the trapezius was measured using a portable electromyographer. The recorded data on muscle movements and electrical activity were synchronized. Subjective evaluations of acceptability were evaluated using a visual analog scale. RESULTS AND CONCLUSIONS: The prototypes with handles at a 30° angle produced the highest acceptability ratings, more neutral wrist positions, lower levels of electromyographic activity for the upper trapezius, and lower elevation angles for the arms. The different measurement methods were complementary in evaluating the upper limbs during handling.

  20. PROCESS MODELLING OF ROCK SAMPLE HANDLING IN PETROPHYSICAL LABORATORY

    Directory of Open Access Journals (Sweden)

    Adaleta Perković

    2010-12-01

    Full Text Available Everyday procedures carried out in petrophysical laboratory can be defined as a complete cycle of business processes. Sample handling process is one of the most significant and demanding procedures. It starts with sample receiving in laboratory and then subsequently, series of analyses and measurements are carrying out resulting in petrophysical parameters. Sample handling process ends with sample storage and archiving of obtained measurement data. Process model is used for description of repeating activities. Sample handling process is presented by graphical method and use of eEPC diagram (extended Event-Driven Process Chain which describe process based on events. Created process model jointly binds static laboratory resources (measuring instruments, computers and data, speeds up process with increasing the user’s efficiency and with improvements of data and information exchange. Besides flow of activity, model of data sample handling includes information about system components (laboratory equipment and software applications that carry out activities. Described model, with minor modifications and adaptations, can be used in any laboratory that is dealing with samples (the paper is published in Croatian.

  1. Development of standard components for remote handling

    Energy Technology Data Exchange (ETDEWEB)

    Taguchi, Kou; Kakudate, Satoshi; Nakahira, Masataka; Ito, Akira [Japan Atomic Energy Research Inst., Tokai, Ibaraki (Japan). Tokai Research Establishment

    1998-04-01

    The core of Fusion Experimental Reactor consists of various components such as superconducting magnets and forced-cooled in-vessel components, which are remotely maintained due to intense of gamma radiation. Mechanical connectors such as cooling pipe connections, insulation joints and electrical connectors are commonly used for maintenance of these components and have to be standardized in terms of remote handling. This paper describes these mechanical connectors developed as the standard component compatible with remote handling and tolerable for radiation. (author)

  2. Safety Training: "Manual Handling" course in September

    CERN Multimedia

    Safety Training, HSE Unit

    2016-01-01

    The next "Manual Handling" course will be given, in French, on 26 September 2016. This course is designed for anyone required to carry out manual handling of loads in the course of their work.   The main objective of this course is to adopt and apply the basic principles of physical safety and economy of effort. There are places available. If you are interested in following this course, please fill an EDH training request via our catalogue. 

  3. HANDLING, STORAGE AND IRON ORE QUALITY

    Directory of Open Access Journals (Sweden)

    Fabiana Fonseca Fortes

    2012-06-01

    Full Text Available This paper aims to identify handling and storage impact in iron ore quality, in their physical and chemical characteristics most important for a mining. It is tried to show the interferences in iron ore quality caused by the handling equipment and stockpiling. The research is restricted to Complexo Vargem Grande (Vale. The timeline was demarcated based on the formation of stockpiling. The fieldwork enables data collection and distinction of the routine procedures of casual operations handling. The quantitative analysis is conducted by the statistical method. As a conclusion, handling and storage identified are able to insert changes in physical and chemical characteristics of iron ore. Storage contributes to reduce variability of silica and alumina concentrations, but contributes too particle size deterioration. The handling induces degradation and segregation. However, there is the possibility to decrease handling of the ore and to establish the ideal size of stocks on the system in study, improving the efficiency of the system and consequent in global costs.

  4. Preliminary Safety Design Report for Remote Handled Low-Level Waste Disposal Facility

    Energy Technology Data Exchange (ETDEWEB)

    Timothy Solack; Carol Mason

    2012-03-01

    A new onsite, remote-handled low-level waste disposal facility has been identified as the highest ranked alternative for providing continued, uninterrupted remote-handled low-level waste disposal for remote-handled low-level waste from the Idaho National Laboratory and for nuclear fuel processing activities at the Naval Reactors Facility. Historically, this type of waste has been disposed of at the Radioactive Waste Management Complex. Disposal of remote-handled low-level waste in concrete disposal vaults at the Radioactive Waste Management Complex will continue until the facility is full or until it must be closed in preparation for final remediation of the Subsurface Disposal Area (approximately at the end of Fiscal Year 2017). This preliminary safety design report supports the design of a proposed onsite remote-handled low-level waste disposal facility by providing an initial nuclear facility hazard categorization, by discussing site characteristics that impact accident analysis, by providing the facility and process information necessary to support the hazard analysis, by identifying and evaluating potential hazards for processes associated with onsite handling and disposal of remote-handled low-level waste, and by discussing the need for safety features that will become part of the facility design.

  5. Conceptual Safety Design Report for the Remote Handled Low-Level Waste Disposal Facility

    Energy Technology Data Exchange (ETDEWEB)

    Boyd D. Christensen

    2010-02-01

    A new onsite, remote-handled LLW disposal facility has been identified as the highest ranked alternative for providing continued, uninterrupted remote-handled LLW disposal for remote-handled LLW from the Idaho National Laboratory and for spent nuclear fuel processing activities at the Naval Reactors Facility. Historically, this type of waste has been disposed of at the Radioactive Waste Management Complex. Disposal of remote-handled LLW in concrete disposal vaults at the Radioactive Waste Management Complex will continue until the facility is full or until it must be closed in preparation for final remediation of the Subsurface Disposal Area (approximately at the end of Fiscal Year 2017). This conceptual safety design report supports the design of a proposed onsite remote-handled LLW disposal facility by providing an initial nuclear facility hazard categorization, by identifying potential hazards for processes associated with onsite handling and disposal of remote-handled LLW, by evaluating consequences of postulated accidents, and by discussing the need for safety features that will become part of the facility design.

  6. [Clinical Handling of Patients with Dissociative Disorders].

    Science.gov (United States)

    Okano, Kenichiro

    2015-01-01

    This paper discusses the way informed psychiatrists are expected to handle dissociative patients in clinical situations, with a specific focus on dissociative identity disorders and dissociative fugue. On the initial interview with dissociative patients, information on their history of trauma and any nascent dissociative symptoms in their childhood should be carefully obtained. Their level of stress in their current life should also be assessed in order to understand their symptomatology, as well as to predict their future clinical course. A psychoeducational approach is crucial; it might be helpful to give information on dissociative disorder to these patients as well as their family members in order to promote their adherence to treatment. Regarding the symptomatology of dissociative disorders, detailed symptoms and the general clinical course are presented. It was stressed that dissociative identity disorder and dissociative fugue, the most high-profile dissociative disorders, are essentially different in their etiology and clinical presentation. Dissociative disorders are often confused with and misdiagnosed as psychotic disorders, such as schizophrenia. Other conditions considered in terms of the differential diagnosis include borderline personality disorder as well as temporal lobe epilepsy. Lastly, the therapeutic approach to dissociative identity disorder is discussed. Each dissociative identity should be understood as potentially representing some traumatically stressful event in the past. The therapist should be careful not to excessively promote the creation or elaboration of any dissociative identities. Three stages are proposed in the individual psychotherapeutic process. In the initial stage, a secure environment and stabilization of symptoms should be sought. The second stage consists of aiding the "host" personality to make use of other more adaptive coping skills in their life. The third stage involves coaching as well as continuous awareness of

  7. Remote-Handled Low-Level Waste Disposal Project Code of Record

    Energy Technology Data Exchange (ETDEWEB)

    S.L. Austad, P.E.; L.E. Guillen, P.E.; C. W. McKnight, P.E.; D. S. Ferguson, P.E.

    2012-06-01

    The Remote-Handled Low-Level Waste (LLW) Disposal Project addresses an anticipated shortfall in remote-handled LLW disposal capability following cessation of operations at the existing facility, which will continue until it is full or until it must be closed in preparation for final remediation of the Subsurface Disposal Area (approximately at the end of Fiscal Year 2017). Development of a new onsite disposal facility will provide necessary remote-handled LLW disposal capability and will ensure continuity of operations that generate remote-handled LLW. This report documents the Code of Record for design of a new LLW disposal capability. The report is owned by the Design Authority, who can authorize revisions and exceptions. This report will be retained for the lifetime of the facility.

  8. Remote-Handled Low-Level Waste Disposal Project Code of Record

    Energy Technology Data Exchange (ETDEWEB)

    S.L. Austad, P.E.; L.E. Guillen, P.E.; C. W. McKnight, P.E.; D. S. Ferguson, P.E.

    2012-04-01

    The Remote-Handled Low-Level Waste (LLW) Disposal Project addresses an anticipated shortfall in remote-handled LLW disposal capability following cessation of operations at the existing facility, which will continue until it is full or until it must be closed in preparation for final remediation of the Subsurface Disposal Area (approximately at the end of Fiscal Year 2017). Development of a new onsite disposal facility will provide necessary remote-handled LLW disposal capability and will ensure continuity of operations that generate remote-handled LLW. This report documents the Code of Record for design of a new LLW disposal capability. The report is owned by the Design Authority, who can authorize revisions and exceptions. This report will be retained for the lifetime of the facility.

  9. Remote-Handled Low-Level Waste Disposal Project Code of Record

    Energy Technology Data Exchange (ETDEWEB)

    Austad, S. L. [Idaho National Lab. (INL), Idaho Falls, ID (United States); Guillen, L. E. [Idaho National Lab. (INL), Idaho Falls, ID (United States); McKnight, C. W. [Idaho National Lab. (INL), Idaho Falls, ID (United States); Ferguson, D. S. [Idaho National Lab. (INL), Idaho Falls, ID (United States)

    2015-04-01

    The Remote-Handled Low-Level Waste (LLW) Disposal Project addresses an anticipated shortfall in remote-handled LLW disposal capability following cessation of operations at the existing facility, which will continue until it is full or until it must be closed in preparation for final remediation of the Subsurface Disposal Area (approximately at the end of Fiscal Year 2017). Development of a new onsite disposal facility will provide necessary remote-handled LLW disposal capability and will ensure continuity of operations that generate remote-handled LLW. This report documents the Code of Record for design of a new LLW disposal capability. The report is owned by the Design Authority, who can authorize revisions and exceptions. This report will be retained for the lifetime of the facility.

  10. Remote-Handled Low-Level Waste Disposal Project Code of Record

    Energy Technology Data Exchange (ETDEWEB)

    S.L. Austad, P.E.; L.E. Guillen, P.E.; C. W. McKnight, P.E.; D. S. Ferguson, P.E.

    2014-06-01

    The Remote-Handled Low-Level Waste (LLW) Disposal Project addresses an anticipated shortfall in remote-handled LLW disposal capability following cessation of operations at the existing facility, which will continue until it is full or until it must be closed in preparation for final remediation of the Subsurface Disposal Area (approximately at the end of Fiscal Year 2017). Development of a new onsite disposal facility will provide necessary remote-handled LLW disposal capability and will ensure continuity of operations that generate remote-handled LLW. This report documents the Code of Record for design of a new LLW disposal capability. The report is owned by the Design Authority, who can authorize revisions and exceptions. This report will be retained for the lifetime of the facility.

  11. Remote-Handled Low-Level Waste Disposal Project Code of Record

    Energy Technology Data Exchange (ETDEWEB)

    S.L. Austad, P.E.; L.E. Guillen, P.E.; C. W. McKnight, P.E.; D. S. Ferguson, P.E.

    2011-04-01

    The Remote-Handled Low-Level Waste (LLW) Disposal Project addresses an anticipated shortfall in remote-handled LLW disposal capability following cessation of operations at the existing facility, which will continue until it is full or until it must be closed in preparation for final remediation of the Subsurface Disposal Area (approximately at the end of Fiscal Year 2017). Development of a new onsite disposal facility, the highest ranked alternative, will provide necessary remote-handled LLW disposal capability and will ensure continuity of operations that generate remote-handled LLW. This report documents the Code of Record for design of a new LLW disposal capability. The report is owned by the Design Authority, who can authorize revisions and exceptions. This report will be retained for the lifetime of the facility.

  12. Remote-Handled Low-Level Waste Disposal Project Code of Record

    Energy Technology Data Exchange (ETDEWEB)

    S.L. Austad, P.E.; L.E. Guillen, P.E.; C. W. McKnight, P.E.; D. S. Ferguson, P.E.

    2011-01-01

    The Remote-Handled Low-Level Waste (LLW) Disposal Project addresses an anticipated shortfall in remote-handled LLW disposal capability following cessation of operations at the existing facility, which will continue until it is full or until it must be closed in preparation for final remediation of the Subsurface Disposal Area (approximately at the end of Fiscal Year 2017). Development of a new onsite disposal facility, the highest ranked alternative, will provide necessary remote-handled LLW disposal capability and will ensure continuity of operations that generate remote-handled LLW. This report documents the Code of Record for design of a new LLW disposal capability. The report is owned by the Design Authority, who can authorize revisions and exceptions. This report will be retained for the lifetime of the facility.

  13. Construction and operation of replacement hazardous waste handling facility at Lawrence Berkeley Laboratory. Environmental Assessment

    Energy Technology Data Exchange (ETDEWEB)

    1992-09-01

    The US Department of Energy (DOE) has prepared an environmental assessment (EA), DOE/EA-0423, for the construction and operation of a replacement hazardous waste handling facility (HWHF) and decontamination of the existing HWHF at Lawrence Berkeley Laboratory (LBL), Berkeley, California. The proposed facility would replace several older buildings and cargo containers currently being used for waste handling activities and consolidate the LBL`s existing waste handling activities in one location. The nature of the waste handling activities and the waste volume and characteristics would not change as a result of construction of the new facility. Based on the analysis in the EA, DOE has determined that the proposed action would not constitute a major Federal action significantly affecting the quality of the human environment within the meaning of the National Environmental Policy Act (NEPA) of 1969, 42 USC. 4321 et seq. Therefore, an environmental impact statement is not required.

  14. Airborne nanoparticle exposures associated with the manual handling of nanoalumina and nanosilver in fume hoods

    Science.gov (United States)

    Tsai, Su-Jung (Candace); Ada, Earl; Isaacs, Jacqueline A.; Ellenbecker, Michael J.

    2009-01-01

    Manual handling of nanoparticles is a fundamental task of most nanomaterial research; such handling may expose workers to ultrafine or nanoparticles. Recent studies confirm that exposures to ultrafine or nanoparticles produce adverse inflammatory responses in rodent lungs and such particles may translocate to other areas of the body, including the brain. An important method for protecting workers handling nanoparticles from exposure to airborne nanoparticles is the laboratory fume hood. Such hoods rely on the proper face velocity for optimum performance. In addition, several other hood design and operating factors can affect worker exposure. Handling experiments were performed to measure airborne particle concentration while handling nanoparticles in three fume hoods located in different buildings under a range of operating conditions. Nanoalumina and nanosilver were selected to perform handling experiments in the fume hoods. Air samples were also collected on polycarbonate membrane filters and particles were characterized by scanning electron microscopy. Handling tasks included transferring particles from beaker to beaker by spatula and by pouring. Measurement locations were the room background, the researcher's breathing zone and upstream and downstream from the handling location. Variable factors studied included hood design, transfer method, face velocity/sash location and material types. Airborne particle concentrations measured at breathing zone locations were analyzed to characterize exposure level. Statistics were used to test the correlation between data. The test results found that the handling of dry powders consisting of nano-sized particles inside laboratory fume hoods can result in a significant release of airborne nanoparticles from the fume hood into the laboratory environment and the researcher's breathing zone. Many variables were found to affect the extent of particle release including hood design, hood operation (sash height, face velocity

  15. 7 CFR 948.23 - Handling for special purposes.

    Science.gov (United States)

    2010-01-01

    ... Order Regulating Handling Regulation § 948.23 Handling for special purposes. Upon the basis of....77, or any combination thereof, to facilitate handling of potatoes for (a) Relief or charity; (b...

  16. 7 CFR 959.53 - Handling for special purposes.

    Science.gov (United States)

    2010-01-01

    ... Regulating Handling Regulations § 959.53 Handling for special purposes. Regulations in effect pursuant to §§ 959.42, 959.52, or 959.60 may be modified, suspended, or terminated to facilitate handling of...

  17. 7 CFR 929.60 - Handling for special purposes.

    Science.gov (United States)

    2010-01-01

    ... LONG ISLAND IN THE STATE OF NEW YORK Order Regulating Handling Reports and Records § 929.60 Handling... facilitate handling of excess cranberries for the following purposes: (a) Charitable institutions;...

  18. Design and Synthesis of Microscale Opto-Magnetic Trapping Handles

    Science.gov (United States)

    Lawson, Joseph L.

    Opto-Magnetic Trapping (OMT) is a novel micromanipulation technology capable of translating particles with nanometer precision and producing forces on the order of pico-Newtons. OMT combines the benefits of optical trapping (OT) to manipulate handle particles in translational directions and magnetic trapping (MT) to provide rotational control. This combined manipulation technology shows promise for applications ranging from novel single molecule force spectroscopy to advanced manufacturing of smart micro or nano structures. Successful OMT requires handles containing material properties amenable to both OT and MT individually. Since these material properties are traditionally exclusive, novel anisotropic handles must be synthesized to accommodate both micromanipulation technologies. This body of research advances the state of the art in micromanipulation technology by addressing the fundamental material incompatibility issues associated with OMT. Novel micro-scale "patchy" handle particles were fabricated using a glancing angle deposition (GLAD) process. Due to their composite design combining dielectric and ferromagnetic materials, these particles successfully demonstrated OMT manipulation. These particles, along with the developed GLAD fabrication process, improve upon the current state of the art by enabling the robust synthesis of a wider range of particle sizes. Furthermore, the magnetic moments of these particles can be more accurately controlled over a wider range including producing magnetic moments grater than is capable with current techniques. A thorough numerical simulation was also conducted to identify the variation of OT performance of these patchy particles with respect to standard dielectric-only OT handles. While variations in trapping location do exist, they were found to be within an acceptable range for OMT applications and are still capable of manipulation with nanometer precision.

  19. Assessing the preparedness of research integrity officers (RIOs) to appropriately handle possible research misconduct cases.

    Science.gov (United States)

    Bonito, Arthur J; Titus, Sandra L; Wright, David E

    2012-12-01

    Institutions receiving federal funding for research from the U.S.Public Health Service need to have policies and procedures to both prevent research misconduct and to adjudicate it when it occurs. The person who is designated to handle research misconduct is typically referred to as the research integrity officer (RIO). In this interview study we report on 79 RIOs who describe how they would handle allegations of research misconduct. Their responses were compared to two expert RIOs. The responses to the allegations in the scenarios demonstrated that RIOs are not uniformly well prepared to handle activities associated with reported allegations of research misconduct. We recommend greater preparation through directed training, use of check lists of possible behaviors necessary to consider when situations arise, being involved in a network of RIOs so one can discuss options, and the possible need to certify RIOs.

  20. The Payload Data Handling and Telemetry Systems of Gaia

    CERN Document Server

    Portell, J; García-Berro, E; Geijo, E M; Portell, Jordi; Luri, Xavier; Garcia-Berro, Enrique; Geijo, Enrique M.

    2005-01-01

    The Payload Data Handling System (PDHS) of Gaia is a technological challenge, since it will have to process a huge amount of data with limited resources. Its main tasks include the optimal codification of science data, its packetisation and its compression, before being stored on-board ready to be transmitted. Here we describe a set of proposals for its design, as well as some simulators developed to optimise and test these proposals.

  1. Evolving the JET virtual reality system for delivering the JET EP2 shutdown remote handling tasks

    Energy Technology Data Exchange (ETDEWEB)

    Williams, Adrian, E-mail: adrian.williams@oxfordtechnologies.co.uk [Oxford Technologies Ltd., 7 Nuffield Way, Abingdon, Oxon, OX14 1RJ (United Kingdom); JET-EFDA, Culham Science Centre, Abingdon, OX14 3DB (United Kingdom); Sanders, Stephen [Oxford Technologies Ltd., 7 Nuffield Way, Abingdon, Oxon, OX14 1RJ (United Kingdom); JET-EFDA, Culham Science Centre, Abingdon, OX14 3DB (United Kingdom); Weder, Gerard [Tree-C Technology BV, Buys Ballotstraat 8, 6716 BL Ede (Netherlands); JET-EFDA, Culham Science Centre, Abingdon, OX14 3DB (United Kingdom); Bastow, Roger; Allan, Peter; Hazel, Stuart [CCFE, Culham Science Centre, Abingdon, OX14 3DB (United Kingdom); JET-EFDA, Culham Science Centre, Abingdon, OX14 3DB (United Kingdom)

    2011-10-15

    The quality, functionality and performance of the virtual reality (VR) system used at JET for preparation and implementation of remote handling (RH) operations has been progressively enhanced since its first use in the original JET remote handling shutdown in 1998. As preparation began for the JET EP2 (Enhanced Performance 2) shutdown it was recognised that the VR system being used was unable to cope with the increased functionality and the large number of 3D models needed to fully represent the JET in-vessel components and tooling planned for EP2. A bespoke VR software application was developed in collaboration with the OEM, which allowed enhancements to be made to the VR system to meet the requirements of JET remote handling in preparation for EP2. Performance improvements required to meet the challenges of EP2 could not be obtained from the development of the new VR software alone. New methodologies were also required to prepare source, CATIA models for use in the VR using a collection of 3D software packages. In collaboration with the JET drawing office, techniques were developed within CATIA using polygon reduction tools to reduce model size, while retaining surface detail at required user limits. This paper will discuss how these developments have played an essential part in facilitating EP2 remote handling task development and examine their impact during the EP2 shutdown.

  2. Developing Singapore School Leaders to Handle Complexity in Times of Uncertainty

    Science.gov (United States)

    Ng, Pak Tee

    2013-01-01

    In times of uncertainty, university faculties have a duty to prepare school leaders to handle complexity, as the number of variables in the educational system and the interactivity of variables increase exponentially. The Leaders in Education Program (LEP) is a 6-month full-time program at the Singapore National Institute of Education (NIE, which…

  3. Quinone-induced protein handling changes: Implications for major protein handling systems in quinone-mediated toxicity

    Energy Technology Data Exchange (ETDEWEB)

    Xiong, Rui; Siegel, David; Ross, David, E-mail: david.ross@ucdenver.edu

    2014-10-15

    Para-quinones such as 1,4-Benzoquinone (BQ) and menadione (MD) and ortho-quinones including the oxidation products of catecholamines, are derived from xenobiotics as well as endogenous molecules. The effects of quinones on major protein handling systems in cells; the 20/26S proteasome, the ER stress response, autophagy, chaperone proteins and aggresome formation, have not been investigated in a systematic manner. Both BQ and aminochrome (AC) inhibited proteasomal activity and activated the ER stress response and autophagy in rat dopaminergic N27 cells. AC also induced aggresome formation while MD had little effect on any protein handling systems in N27 cells. The effect of NQO1 on quinone induced protein handling changes and toxicity was examined using N27 cells stably transfected with NQO1 to generate an isogenic NQO1-overexpressing line. NQO1 protected against BQ–induced apoptosis but led to a potentiation of AC- and MD-induced apoptosis. Modulation of quinone-induced apoptosis in N27 and NQO1-overexpressing cells correlated only with changes in the ER stress response and not with changes in other protein handling systems. These data suggested that NQO1 modulated the ER stress response to potentiate toxicity of AC and MD, but protected against BQ toxicity. We further demonstrated that NQO1 mediated reduction to unstable hydroquinones and subsequent redox cycling was important for the activation of the ER stress response and toxicity for both AC and MD. In summary, our data demonstrate that quinone-specific changes in protein handling are evident in N27 cells and the induction of the ER stress response is associated with quinone-mediated toxicity. - Highlights: • Unstable hydroquinones contributed to quinone-induced ER stress and toxicity.

  4. Effective Teaching Practices in Handling Non Readers

    Directory of Open Access Journals (Sweden)

    Jacklyn S. Dacalos

    2016-08-01

    Full Text Available The study determined the effective teaching practices in handling nonreaders. This seeks to answer the following objectives: describe the adjustments, effective strategies, and scaffolds utilized by teachers in handling nonreaders; differentiate the teachers’ reading adjustments, strategies and scaffolds in teaching nonreaders; analyze the teaching reading efficiency of nonreaders using effective teaching reading strategies; and find significant correlation of nonreaders’ grades and reading teachers’ reading adjustments, strategies and scaffolds. This study utilized mixed methods of research. Case studies of five public schools teachers were selected as primary subjects, who were interviewed in handling nonreaders in the areas of adjustments, strategies, and reading scaffolds. Actual teaching observation was conducted according to the five subjects’ most convenient time. In ascertaining the nonreaders’ academic performance, the students’ grades in English subject was analyzed using T-Test within subject design. Handling nonreaders in order to read and understand better in the lesson is an arduous act, yet; once done with effectiveness and passion, it yielded a great amount of learning success. Effective teaching practices in handling nonreaders comprised the use of teachers’ adjustments, strategies, and scaffolds to establish reading mastery, exposing them to letter sounds, short stories, and the use of follow-up. WH questions enhanced their reading performance significantly. Variations of reading teachers’ nature as: an enabler, a facilitator, a humanist, a behaviorist, and an expert, as regards to their teaching practices, were proven significant to students’ reading effectiveness.

  5. Hygienic food handling behaviours. An application of the Theory of Planned Behaviour.

    Science.gov (United States)

    Mullan, Barbara A; Wong, Cara L

    2009-06-01

    It is estimated that 5.4 million Australians get sick annually from eating contaminated food and that up to 20% of this illness results from food handling behaviour. A study was undertaken to investigate the efficacy of the Theory of Planned Behaviour (TPB) including past behaviour in predicting safe food handling intention and behaviour. One hundred and nine participants completed questionnaires regarding their attitudes, perceived behavioural control (PBC), subjective norm, intentions and past behaviour. Behaviour was measured 4 weeks later. The TPB predicted a high proportion of variance in both intentions and behaviour, and past behaviour/habit was found to be the strongest predictor of behaviour. The results of the present study suggest interventions aimed at increasing safe food handling intentions should focus on the impact of normative influences and perceptions of control over their food handling environment; whereas interventions to change actual behaviour should attempt to increase hygienic food handling as a habitual behaviour.

  6. Sample Handling in Extreme Environments

    Science.gov (United States)

    Avellar, Louisa; Badescu, Mircea; Sherrit, Stewart; Bar-Cohen, Yoseph

    2013-01-01

    Harsh environments, such as that on Venus, preclude the use of existing equipment for functions that involve interaction with the environment. The operating limitations of current high temperature electronics are well below the actual temperature and pressure found on Venus (460 deg C and 92 atm), so proposed lander configurations typically include a pressure vessel where the science instruments are kept at Earth-like temperature and pressure (25 deg C and 1 atm). The purpose of this project was to develop and demonstrate a method for sample transfer from an external drill to internal science instruments for a lander on Venus. The initial concepts were string and pneumatically driven systems; and the latter system was selected for its ability to deliver samples at very high speed. The pneumatic system was conceived to be driven by the pressure difference between the Venusian atmosphere and the inside of the lander. The pneumatic transfer of a small capsule was demonstrated, and velocity data was collected from the lab experiment. The sample transfer system was modeled using CAD software and prototyped using 3D printing. General structural and thermal analyses were performed to approximate the proposed system's mass and effects on the temperature and pressure inside of the lander. Additionally, a sampler breadboard for use on Titan was tested and functionality problems were resolved.

  7. Sample Handling in Extreme Environments

    Science.gov (United States)

    Avellar, Louisa; Badescu, Mircea; Sherrit, Stewart; Bar-Cohen, Yoseph

    2013-01-01

    Harsh environments, such as that on Venus, preclude the use of existing equipment for functions that involve interaction with the environment. The operating limitations of current high temperature electronics are well below the actual temperature and pressure found on Venus (460 deg C and 92 atm), so proposed lander configurations typically include a pressure vessel where the science instruments are kept at Earth-like temperature and pressure (25 deg C and 1 atm). The purpose of this project was to develop and demonstrate a method for sample transfer from an external drill to internal science instruments for a lander on Venus. The initial concepts were string and pneumatically driven systems; and the latter system was selected for its ability to deliver samples at very high speed. The pneumatic system was conceived to be driven by the pressure difference between the Venusian atmosphere and the inside of the lander. The pneumatic transfer of a small capsule was demonstrated, and velocity data was collected from the lab experiment. The sample transfer system was modeled using CAD software and prototyped using 3D printing. General structural and thermal analyses were performed to approximate the proposed system's mass and effects on the temperature and pressure inside of the lander. Additionally, a sampler breadboard for use on Titan was tested and functionality problems were resolved.

  8. How renal cells handle urea.

    Science.gov (United States)

    Bagnasco, S M

    2000-01-01

    The urine concentration process requires an osmolality gradient along the renal cortico-medullary axis, with highest values in the renal papilla. NaCl and urea are the major solutes in the renal inner medulla, concentrations of urea up to 500-600 mM are found in the rat renal papilla. Urea can diffuse across cell membranes and contributes to balance intracellular and extracellular osmotic equilibrium. However, urea has perturbing effects on enzyme activity, and in concentrations above 300 mM is toxic for renal cultured cells. There is increasing evidence that urea can induce cellular responses distinct from those due to NaCl and other non-permeable solutes, including upregulation of immediate-early genes (IEGs). Urea transport by epithelial and endothelial cells is important for intra-medullary urea recycling and preservation of high urea concentration in the inner medulla. Trans-cellular movement of urea in cells expressing urea transporters may influence intracellular levels of this solute and modulate urea-induced signaling pathways. Regulation of urea transporters expression and activity can therefore be viewed as one aspect of cellular adaptation to urea. We have identified tonicity-responsive transcription as one mechanism regulating expression of the urea transporter UT-A. The short-term and long-term effects of variable extracellular urea concentration on the function of renal cells remain still unclear.

  9. Mars Sample Handling Protocol Workshop Series: Workshop 4

    Science.gov (United States)

    Race Margaret S. (Editor); DeVincenzi, Donald L. (Editor); Rummel, John D. (Editor); Acevedo, Sara E. (Editor)

    2001-01-01

    In preparation for missions to Mars that will involve the return of samples to Earth, it will be necessary to prepare for the receiving, handling, testing, distributing, and archiving of martian materials here on Earth. Previous groups and committees have studied selected aspects of sample return activities, but specific detailed protocols for the handling and testing of returned samples must still be developed. To further refine the requirements for sample hazard testing and to develop the criteria for subsequent release of sample materials from quarantine, the NASA Planetary Protection Officer convened a series of workshops in 2000-2001. The overall objective of the Workshop Series was to produce a Draft Protocol by which returned martian sample materials can be assessed for biological hazards and examined for evidence of life (extant or extinct) while safeguarding the purity of the samples from possible terrestrial contamination. This report also provides a record of the proceedings of Workshop 4, the final Workshop of the Series, which was held in Arlington, Virginia, June 5-7, 2001. During Workshop 4, the sub-groups were provided with a draft of the protocol compiled in May 2001 from the work done at prior Workshops in the Series. Then eight sub-groups were formed to discuss the following assigned topics: Review and Assess the Draft Protocol for Physical/Chemical Testing Review and Assess the Draft Protocol for Life Detection Testing Review and Assess the Draft Protocol for Biohazard Testing Environmental and Health/Monitoring and Safety Issues Requirements of the Draft Protocol for Facilities and Equipment Contingency Planning for Different Outcomes of the Draft Protocol Personnel Management Considerations in Implementation of the Draft Protocol Draft Protocol Implementation Process and Update Concepts This report provides the first complete presentation of the Draft Protocol for Mars Sample Handling to meet planetary protection needs. This Draft Protocol

  10. ARRA Material Handling Equipment Composite Data Products: Data Through Quarter 4 of 2012

    Energy Technology Data Exchange (ETDEWEB)

    Kurtz, J.; Sprik, S.; Ainscough, C.; Saur, G.; Post, M.; Peters, M.; Ramsden, T.

    2013-05-01

    This presentation from the U.S. Department of Energy's National Renewable Energy Laboratory includes American Recovery and Reinvestment Act (ARRA) fuel cell material handling equipment composite data products for data through the fourth quarter of 2012.

  11. 21 CFR 1250.38 - Toilet and lavatory facilities for use of food-handling employees.

    Science.gov (United States)

    2010-04-01

    ... directing food-handling employees to wash their hands after each use of toilet facilities shall be posted so as to be readily observable by such employees. Hand washing facilities shall include soap, sanitary...

  12. Grain Handling Facility at Freeman, Washington Proposed to Superfund Cleanup List

    Science.gov (United States)

    (March 24, 2015 - Seattle) The U.S. Environmental Protection Agency is proposing to add the Grain Handling Facility at Freeman, in Spokane County, Washington, to the Superfund National Priorities List. The proposed listing includes a 60-day public comment

  13. Practical Tips for the Safe Handling of Micro-organisms in Schools

    Science.gov (United States)

    Holt, G.

    1974-01-01

    Outlines safe laboratory procedures for the handling of micro-organisms including aseptic technique, manipulation of cultures, and treatment of contaminated equipment. Identifies the principal hazard as the microbial aerosol, explains its possible effects, and describes the appropriate precautions. (GS)

  14. Investigation into slipping and falling accidents and materials handling in the South African mining industry.

    CSIR Research Space (South Africa)

    Schutte, PC

    2003-03-01

    Full Text Available was conducted at a gold mine, a colliery and a quarry to establish current manual materials handling practices. This included walk-through observational surveys of the work facilities to observe obvious ergonomics-related risk factors....

  15. ARRA Material Handling Equipment Composite Data Products: Data through Quarter 2 of 2012

    Energy Technology Data Exchange (ETDEWEB)

    Kurtz, J.; Sprik, S.; Ramsden, T.; Ainscough, C.; Saur, G.

    2012-10-01

    This presentation from the U.S. Department of Energy's National Renewable Energy Laboratory includes American Recovery and Reinvestment Act (ARRA) fuel cell material handling equipment composite data products for data through the second quarter of 2012.

  16. Randomly removing g handles at once

    CERN Document Server

    Borradaile, Glencora; Sidiropoulos, Anastasios

    2010-01-01

    Indyk and Sidiropoulos (2007) proved that any orientable graph of genus $g$ can be probabilistically embedded into a graph of genus $g-1$ with constant distortion. Viewing a graph of genus $g$ as embedded on the surface of a sphere with $g$ handles attached, Indyk and Sidiropoulos' method gives an embedding into a distribution over planar graphs with distortion $2^{O(g)}$, by iteratively removing the handles. By removing all $g$ handles at once, we present a probabilistic embedding with distortion $O(g^2)$ for both orientable and non-orientable graphs. Our result is obtained by showing that the nimum-cut graph of Erickson and Har Peled (2004) has low dilation, and then randomly cutting this graph out of the surface using the Peeling Lemma of Lee and Sidiropoulos (2009).

  17. Handling Protest Responses in Contingent Valuation Surveys.

    Science.gov (United States)

    Pennington, Mark; Gomes, Manuel; Donaldson, Cam

    2017-08-01

    Protest responses, whereby respondents refuse to state the value they place on the health gain, are commonly encountered in contingent valuation (CV) studies, and they tend to be excluded from analyses. Such an approach will be biased if protesters differ from non-protesters on characteristics that predict their responses. The Heckman selection model has been commonly used to adjust for protesters, but its underlying assumptions may be implausible in this context. We present a multiple imputation (MI) approach to appropriately address protest responses in CV studies, and compare it with the Heckman selection model. This study exploits data from the multinational EuroVaQ study, which surveyed respondents' willingness-to-pay (WTP) for a Quality Adjusted Life Year (QALY). Here, our simulation study assesses the relative performance of MI and Heckman selection models across different realistic settings grounded in the EuroVaQ study, including scenarios with different proportions of missing data and non-response mechanisms. We then illustrate the methods in the EuroVaQ study for estimating mean WTP for a QALY gain. We find that MI provides lower bias and mean squared error compared with the Heckman approach across all considered scenarios. The simulations suggest that the Heckman approach can lead to considerable underestimation or overestimation of mean WTP due to violations in the normality assumption, even after log-transforming the WTP responses. The case study illustrates that protesters are associated with a lower mean WTP for a QALY gain compared with non-protesters, but that the results differ according to method for handling protesters. MI is an appropriate method for addressing protest responses in CV studies.

  18. Handling Qualities of Large Rotorcraft in Hover and Low Speed

    Science.gov (United States)

    Malpica, Carlos; Theodore, Colin R.; Lawrence , Ben; Blanken, Chris L.

    2015-01-01

    According to a number of system studies, large capacity advanced rotorcraft with a capability of high cruise speeds (approx.350 mph) as well as vertical and/or short take-off and landing (V/STOL) flight could alleviate anticipated air transportation capacity issues by making use of non-primary runways, taxiways, and aprons. These advanced aircraft pose a number of design challenges, as well as unknown issues in the flight control and handling qualities domains. A series of piloted simulation experiments have been conducted on the NASA Ames Research Center Vertical Motion Simulator (VMS) in recent years to systematically investigate the fundamental flight control and handling qualities issues associated with the characteristics of large rotorcraft, including tiltrotors, in hover and low-speed maneuvering.

  19. A Review of Screw Conveyors Performance Evaluation During Handling Process

    Directory of Open Access Journals (Sweden)

    Hemad Zareiforoush

    2010-04-01

    Full Text Available This paper reviews recent work on screw conveyors performance evaluation during handling process, especially in the case of agricultural grains and bulk materials. Experimental work has been mainly carried out to determine a range of parameters, such as auger dimension, screw rotational speed, screw clearance, conveyor intake length and conveying angle for horizontal, inclined and vertical screw conveyors. Several measurement techniques including theoretical models and DEM have been utilized to study the screw conveyors performance. However, each of these techniques is limited in its application. Difficulties in representing vortex motion and interactions among conveying grains and between the particles and screw rotating flight have so far limited the success of advanced modeling. Further work is needed to be conducted on screw augers performance to understand and improve the agricultural grains and bulk materials handling process.

  20. Missing data handling methods in medical device clinical trials.

    Science.gov (United States)

    Yan, Xu; Lee, Shiowjen; Li, Ning

    2009-11-01

    One of the major problems in the analysis of clinical trials is missing data caused by patients dropping out before study completion. The issue of missing data can result in biased treatment comparisons and can impact the interpretation of study results. Since the missing data mechanism is unknown and unverifiable in most situations, regulatory agencies often request various sensitivity analyses for handling missing data to evaluate the robustness of study results. This article discusses methods used to handle missing data in medical device clinical trials, focusing on tipping-point analysis as a general approach for the assessment of missing data impact. Tipping points are outcomes that result in a change of study conclusion. Such outcomes can be conveyed to clinical reviewers to determine if they are implausibly unfavorable. The analysis aids clinical reviewers in making judgment regarding treatment effect in the study. Three examples with a reasonably representative range of missing data rate are included to illustrate the methods referred.

  1. Handling of fuel chips - a health problem

    Energy Technology Data Exchange (ETDEWEB)

    Stroemquist, L.H.; Blomqvist, G.; Karlsson, E.; Vincent, A.; Lundgren, R.; Eliasson, L.

    1980-01-01

    An investigation has been made about health problems and occurrence of mold in connection with handling of fuel chips. The investigation was composed of three different parts. First, an inquiry was made to chip stokers about handling, storage etc. of chips as well as possible medical trouble. The answers indicated that symptoms on allergic alveolitis are common among chip stokers, 13% of the answers. Second, a determination of the proportion of living airborne colony-forming mold fungi was made at some chip using units. Third, a pilot study was made to examine the possibilities to improve storability of fuel chips using high-temperature drying.

  2. FISHprep: A Novel Integrated Device for Metaphase FISH Sample Preparation

    DEFF Research Database (Denmark)

    Shah, Pranjul Jaykumar; Vedarethinam, Indumathi; Kwasny, Dorota;

    2011-01-01

    We present a novel integrated device for preparing metaphase chromosomes spread slides (FISHprep). The quality of cytogenetic analysis from patient samples greatly relies on the efficiency of sample pre-treatment and/or slide preparation. In cytogenetic slide preparation, cell cultures are routin...... with minimal handling for metaphase FISH slide preparation....

  3. Remote-handled transuranic system assessment appendices. Volume 2

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-11-01

    Volume 2 of this report contains six appendices to the report: Inventory and generation of remote-handled transuranic waste; Remote-handled transuranic waste site storage; Characterization of remote-handled transuranic waste; RH-TRU waste treatment alternatives system analysis; Packaging and transportation study; and Remote-handled transuranic waste disposal alternatives.

  4. Remote-handled transuranic system assessment appendices. Volume 2

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-11-01

    Volume 2 of this report contains six appendices to the report: Inventory and generation of remote-handled transuranic waste; Remote-handled transuranic waste site storage; Characterization of remote-handled transuranic waste; RH-TRU waste treatment alternatives system analysis; Packaging and transportation study; and Remote-handled transuranic waste disposal alternatives.

  5. 30 CFR 77.1303 - Explosives, handling and use.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Explosives, handling and use. 77.1303 Section... MINES Explosives and Blasting § 77.1303 Explosives, handling and use. (a) Persons who use or handle... treated and handled with the same safety precautions as blasting caps and electric detonators. (o) Capped...

  6. Viability of Existing INL Facilities for Dry Storage Cask Handling

    Energy Technology Data Exchange (ETDEWEB)

    Randy Bohachek; Charles Park; Bruce Wallace; Phil Winston; Steve Marschman

    2013-04-01

    This report evaluates existing capabilities at the INL to determine if a practical and cost effective method could be developed for opening and handling full-sized dry storage casks. The Idaho Nuclear Technology and Engineering Center (INTEC) CPP-603, Irradiated Spent Fuel Storage Facility, provides the infrastructure to support handling and examining casks and their contents. Based on a reasonable set of assumptions, it is possible to receive, open, inspect, remove samples, close, and reseal large bolted-lid dry storage casks at the INL. The capability can also be used to open and inspect casks that were last examined at the TAN Hot Shop over ten years ago. The Castor V/21 and REA-2023 casks can provide additional confirmatory information regarding the extended performance of low-burnup (<45 GWD/MTU) used nuclear fuel. Once a dry storage cask is opened inside CPP-603, used fuel retrieved from the cask can be packaged in a shipping cask, and sent to a laboratory for testing. Testing at the INL’s Materials and Fuels Complex (MFC) can occur starting with shipment of samples from CPP-603 over an on-site road, avoiding the need to use public highways. This reduces cost and reduces the risk to the public. The full suite of characterization methods needed to establish the condition of the fuel exists and MFC. Many other testing capabilities also exist at MFC, but when those capabilities are not adequate, samples can be prepared and shipped to other laboratories for testing. This report discusses how the casks would be handled, what work needs to be done to ready the facilities/capabilities, and what the work will cost.

  7. Viability of Existing INL Facilities for Dry Storage Cask Handling

    Energy Technology Data Exchange (ETDEWEB)

    Bohachek, Randy; Wallace, Bruce; Winston, Phil; Marschman, Steve

    2013-04-30

    This report evaluates existing capabilities at the INL to determine if a practical and cost effective method could be developed for opening and handling full-sized dry storage casks. The Idaho Nuclear Technology and Engineering Center (INTEC) CPP-603, Irradiated Spent Fuel Storage Facility, provides the infrastructure to support handling and examining casks and their contents. Based on a reasonable set of assumptions, it is possible to receive, open, inspect, remove samples, close, and reseal large bolted-lid dry storage casks at the INL. The capability can also be used to open and inspect casks that were last examined at the TAN Hot Shop over ten years ago. The Castor V/21 and REA-2023 casks can provide additional confirmatory information regarding the extended performance of low-burnup (<45 GWD/MTU) used nuclear fuel. Once a dry storage cask is opened inside CPP-603, used fuel retrieved from the cask can be packaged in a shipping cask, and sent to a laboratory for testing. Testing at the INL’s Materials and Fuels Complex (MFC) can occur starting with shipment of samples from CPP-603 over an on-site road, avoiding the need to use public highways. This reduces cost and reduces the risk to the public. The full suite of characterization methods needed to establish the condition of the fuel exists and MFC. Many other testing capabilities also exist at MFC, but when those capabilities are not adequate, samples can be prepared and shipped to other laboratories for testing. This report discusses how the casks would be handled, what work needs to be done to ready the facilities/capabilities, and what the work will cost.

  8. Efficient compensation handling via subjective updates

    NARCIS (Netherlands)

    J. Dedeić (Jovana); J. Pantović (Jovanka); J.A. Pérez Parra (Jorge)

    2017-01-01

    textabstractProgramming abstractions for compensation handling and dynamic update are crucial in specifying reliable interacting systems, such as Collective Adaptive Systems (CAS). Compensations and updates both specify how a system reacts in response to exceptional events. Prior work showed that

  9. Materials handling centre: making business more efficient

    NARCIS (Netherlands)

    B. Bollen (Brian)

    2012-01-01

    textabstractThe aim of the Materials Handling Forum at RSM is to narrow the gap between research and practice by promoting and disseminating academic knowledge, sharing innovative ideas, generating research questions, and co-developing new research themes with industry partners.

  10. Waiting on More than 64 Handles

    Science.gov (United States)

    2015-10-01

    parameter stuct is comprised of an array of handles with a maximum size of MAX_WAIT_OBJECTS and an integer holding the total quantity. Once all the...GIDEP Operations Center P.O. Box 8000 Corona , CA 91718-8000 gidep@gidep.org UNCLASSIFIED Approved for public release; distribution is unlimited. 4 Patricia Alameda Patricia Alameda Andrew Pskowski

  11. Biodiesel Handling and Use Guide (Fifth Edition)

    Energy Technology Data Exchange (ETDEWEB)

    Alleman, Teresa L.; McCormick, Robert L.; Christensen, Earl D.; Fioroni, Gina; Moriarty, Kristi; Yanowitz, Janet

    2016-11-08

    This document is a guide for those who blend, distribute, and use biodiesel and biodiesel blends. It provides basic information on the proper and safe use of biodiesel and biodiesel blends in engines and boilers, and is intended to help fleets, individual users, blenders, distributors, and those involved in related activities understand procedures for handling and using biodiesel fuels.

  12. Australia: round module handling and cotton classing

    Science.gov (United States)

    Round modules of seed cotton produced via on-board module building harvesters are the reality of the cotton industry, worldwide. Although round modules have been available to the industry for almost a decade, there is still no consensus on the best method to handle the modules, particularly when th...

  13. Laboratory rearing and handling of cerambycids

    Science.gov (United States)

    Melody A. Keena

    2017-01-01

    Lack of suitable rearing and handling techniques has hampered research on the biology and control of many species of cerambycids that feed on host species of economic importance. Furthermore, because cerambycids spend most or all of their pre-adult life cycle inside the host plant, the biology of many is not well-known and would be dif

  14. Intertextuality for Handling Complex Environmental Issues

    Science.gov (United States)

    Byhring, Anne Kristine; Knain, Erik

    2016-01-01

    Nowhere is the need for handling complexity more pertinent than in addressing environmental issues. Our study explores students' situated constructs of complexity in unfolding discourses on socio-scientific issues. Students' dialogues in two group-work episodes are analysed in detail, with tools from Systemic Functional Linguistics. We identify…

  15. 340 Waste handling facility interim safety basis

    Energy Technology Data Exchange (ETDEWEB)

    Stordeur, R.T.

    1996-10-04

    This document presents an interim safety basis for the 340 Waste Handling Facility classifying the 340 Facility as a Hazard Category 3 facility. The hazard analysis quantifies the operating safety envelop for this facility and demonstrates that the facility can be operated without a significant threat to onsite or offsite people.

  16. 340 waste handling facility interim safety basis

    Energy Technology Data Exchange (ETDEWEB)

    VAIL, T.S.

    1999-04-01

    This document presents an interim safety basis for the 340 Waste Handling Facility classifying the 340 Facility as a Hazard Category 3 facility. The hazard analysis quantifies the operating safety envelop for this facility and demonstrates that the facility can be operated without a significant threat to onsite or offsite people.

  17. Intertextuality for Handling Complex Environmental Issues

    Science.gov (United States)

    Byhring, Anne Kristine; Knain, Erik

    2016-01-01

    Nowhere is the need for handling complexity more pertinent than in addressing environmental issues. Our study explores students' situated constructs of complexity in unfolding discourses on socio-scientific issues. Students' dialogues in two group-work episodes are analysed in detail, with tools from Systemic Functional Linguistics. We identify…

  18. Goods handling: tugs, trailers and tractors.

    Science.gov (United States)

    Grayson, H

    1980-09-26

    Ease of handling ought to be a priority in any supply and disposal system. Hazel Grayson, senior research officer at the Medical Architecture Research Unit, Polytechnic of North London, suggests that even where driver-operated electric tow tractors cannot be used, other types of electric pulling device should be considered.

  19. 'Safe handling of nanotechnology' ten years on

    Science.gov (United States)

    Maynard, Andrew D.; Aitken, Robert J.

    2016-12-01

    In 2006, a group of scientists proposed five grand challenges to support the safe handling of nanotechnology. Ten years on, Andrew Maynard and Robert Aitken -- two of the original authors -- look at where we have come, and where we still need to go.

  20. Caution required for handling genome editing technology.

    Science.gov (United States)

    Araki, Motoko; Nojima, Kumie; Ishii, Tetsuya

    2014-05-01

    Genome-editing technology, although a robust tool for genetic engineering, is creating indistinct regulatory boundaries between naturally occurring and modified organisms. However, researchers must act with caution in research and development to avoid misleading society. Furthermore, appropriate regulations should be proactively discussed and established for handling genome-editing technology.

  1. Tips for Handling Gourds this Fall Season

    OpenAIRE

    Bratsch, Tony

    2009-01-01

    Each year, more direct market and wholesale growers are adding gourds to their fall sales mix, along with pumpkins, ornamental corn and fall mums. Proper harvest timing, handling and curing are important to ensure maximum longevity of gourds once the consumer brings them home.

  2. Instrumentation to handle thermal polarized neutron beams

    NARCIS (Netherlands)

    Kraan, W.H.

    2004-01-01

    In this thesis we investigate devices needed to handle the polarization of thermal neutron beams: Ï/2-flippers (to start/stop Larmor precession) and Ï-flippers (to reverse polarization/precession direction) and illustrate how these devices are used to investigate the properties of matter and of the

  3. Ergonomics intervention in manual handling of oxygen

    Directory of Open Access Journals (Sweden)

    M Motamedzadeh

    2013-05-01

    Conclusion: With the implementation of ergonomic intervention is casting unit, the risk of exposure to musculoskeletal disorders caused by manual handling of oxygen cylinders was eliminated and safety of employees against the risk of explosion of the cylinders in comparison with before the intervention was improved.

  4. Handling Sparse Data by Successive Abstraction

    CERN Document Server

    Samuelsson, C

    1996-01-01

    A general, practical method for handling sparse data that avoids held-out data and iterative reestimation is derived from first principles. It has been tested on a part-of-speech tagging task and outperformed (deleted) interpolation with context-independent weights, even when the latter used a globally optimal parameter setting determined a posteriori.

  5. 7 CFR 920.11 - Handle.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 8 2010-01-01 2010-01-01 false Handle. 920.11 Section 920.11 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements and Orders; Fruits, Vegetables, Nuts), DEPARTMENT OF AGRICULTURE KIWIFRUIT GROWN IN CALIFORNIA...

  6. 7 CFR 955.7 - Handle.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 8 2010-01-01 2010-01-01 false Handle. 955.7 Section 955.7 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements and Orders; Fruits, Vegetables, Nuts), DEPARTMENT OF AGRICULTURE VIDALIA ONIONS GROWN IN GEORGIA...

  7. Wet handling of solids using submersible pumps

    Energy Technology Data Exchange (ETDEWEB)

    Czarnota, Z.; Fahlgren, M.; Grainger, M. [ITT Flygt Slurry Laboratory, Soina (Sweden)

    1996-12-31

    A complete and efficient concept for handling solids in short distance pumping applications is described. The function of pump, mixer, agitator, and sump have been determined in experimental studies. The major factors that affect pump performance such as impeller design and slurry characteristics are discussed. The results apply to a range of applications in industry and mining. 10 refs., 6 figs.

  8. Handling performance control for hybrid 8-wheel-drive vehicle and simulation verification

    Science.gov (United States)

    Ni, Jun; Hu, Jibin

    2016-08-01

    In order to improve handling performance of a hybrid 8-Wheel-Drive vehicle, the handling performance control strategy was proposed. For armoured vehicle, besides handling stability in high speed, the minimum steer radius in low speed is also a key tactical and technical index. Based on that, the proposed handling performance control strategy includes 'Handling Stability' and 'Radius Minimization' control modes. In 'Handling Stability' control mode, 'Neutralsteer Radio' is defined to adjust the steering characteristics to satisfy different demand in different speed range. In 'Radius Minimization' control mode, the independent motors are controlled to provide an additional yaw moment to decrease the minimum steer radius. In order to verify the strategy, a simulation platform was built including engine and continuously variable transmission systems, generator and battery systems, independent motors and controllers systems, vehicle dynamic and tyre mechanical systems. The simulation results show that the handling performance of the vehicle can be enhanced significantly, and the minimum steer radius can be decreased by 20% which is significant improvement compared to the common level of main battle armoured vehicle around the world.

  9. Event detection and exception handling strategies in the ASDEX Upgrade discharge control system

    Energy Technology Data Exchange (ETDEWEB)

    Treutterer, W., E-mail: Wolfgang.Treutterer@ipp.mpg.de; Neu, G.; Rapson, C.; Raupp, G.; Zasche, D.; Zehetbauer, T.

    2013-10-15

    Highlights: •Event detection and exception handling is integrated in control system architecture. •Pulse control with local exception handling and pulse supervision with central exception handling are strictly separated. •Local exception handling limits the effect of an exception to a minimal part of the controlled system. •Central Exception Handling solves problems requiring coordinated action of multiple control components. -- Abstract: Thermonuclear plasmas are governed by nonlinear characteristics: plasma operation can be classified into scenarios with pronounced features like L and H-mode, ELMs or MHD activity. Transitions between them may be treated as events. Similarly, technical systems are also subject to events such as failure of measurement sensors, actuator saturation or violation of machine and plant operation limits. Such situations often are handled with a mixture of pulse abortion and iteratively improved pulse schedule reference programming. In case of protection-relevant events, however, the complexity of even a medium-sized device as ASDEX Upgrade requires a sophisticated and coordinated shutdown procedure rather than a simple stop of the pulse. The detection of events and their intelligent handling by the control system has been shown to be valuable also in terms of saving experiment time and cost. This paper outlines how ASDEX Upgrade's discharge control system (DCS) detects events and handles exceptions in two stages: locally and centrally. The goal of local exception handling is to limit the effect of an unexpected or asynchronous event to a minimal part of the controlled system. Thus, local exception handling facilitates robustness to failures but keeps the decision structures lean. A central state machine deals with exceptions requiring coordinated action of multiple control components. DCS implements the state machine by means of pulse schedule segments containing pre-programmed waveforms to define discharge goal and control

  10. Command and Data Handling Branch Internship

    Science.gov (United States)

    Billings, Rachel Mae

    2016-01-01

    Modular Integrated Stackable Layers (MISL) is a computer system designed for simple, fast, and cost effective flexible reconfiguration in space environments such as the ISS and Orion projects for various uses. Existing applications include wireless and wired communications, data acquisition and instrumentation, and camera systems, and potential applications include bus protocol converters and subsystem control. MISL is based on Texas Instruments (TI)' MSP430 16-bit ultra-low-power microcontroller device. The purpose of my project was to integrate the MISL system with a liquid crystal display (LCD) touchscreen. The LCD, manufactured by Crystalfontz and part number CFAF320240F-035T-TS, is a 320 by 240 RGB resistive color screen including an optional carrier board. The vast majority of the project was done with Altium Designer, a tool for printed circuit board (PCB) schematic capture, 3D design, and FPGA (Field Programmable Gate Array) development. The new PCB was to allow the LCD to directly stack to the rest of MISL. Research was done with datasheets for the TI microcontroller and touchscreen display in order to meet desired hardware specifications. Documentation on prior MISL projects was also utilized. The initial step was to create a schematic for the LCD, power bus, and data bus connections between components. A layout was then designed with the required physical dimensions, routed traces and vias, power and ground planes, layer stacks, and other specified design rules such as plane clearance and hole size. Multiple consultation sessions were held with Hester Yim, the technical discipline lead for the Command and Data Handling Branch, and Christy Herring, the lead PCB layout designer in the Electronic Design and Manufacturing Branch in order to ensure proper configuration. At the moment, the PCB is awaiting revision by the latter-mentioned branch. Afterwards, the board will begin to undergo the manufacturing and testing process. Throughout the internship at

  11. Handling characteristics of gallium alloy for dental restoration.

    Science.gov (United States)

    Mash, L K; Miller, B H; Nakajima, H; Collard, S M; Guo, I Y; Okabe, T

    1993-12-01

    The handling characteristics of a gallium alloy (Gallium Alloy GF) were compared to those of a spherical high-copper amalgam (Tytin). Ten dentists each restored four identical MO preparations in acrylic typodont teeth (no. 30), two with amalgam and two with gallium alloy. Each restoration was evaluated immediately following completion by the operator for six clinically relevant criteria. Each criterion was scored between 1 and 5, where 1 = very poor, 2 = poor, 3 = fair, 4 = good, and 5 = very good. Three two-sided Mann-Whitney tests were used to compare the median scores for significant differences (P < 0.05). The first test indicated no significant difference between scores for the first- and second-placed restorations, within criteria and within alloy type (n = 10). The second test indicated a significant difference between amalgam and gallium alloy, within criteria and within restoration sequence (n = 10), for each criterion except resistance to fracture during removal of the matrix band. The third test indicated a significant difference between amalgam and gallium alloy, within each criteria, combining scores for first- and second-placed restorations (n = 20). During simulated clinical placement, amalgam was rated significantly higher than gallium alloy in each handling characteristic evaluated.

  12. Data handling and representation of freeform surfaces

    Science.gov (United States)

    Steinkopf, Ralf; Dick, Lars; Kopf, Tino; Gebhardt, Andreas; Risse, Stefan; Eberhardt, Ramona

    2011-10-01

    Freeform surfaces enable innovative optics. They are not limited by axis symmetry and hence they are almost free in design. They are used to reduce the installation space and enhance the performance of optical elements. State of the art optical design tools are computing with powerful algorithms to simulate freeform surfaces. Even new mathematical approaches are under development /1/. In consequence, new optical designs /2/ are pushing the development of manufacturing processes consequently and novel types of datasets have to proceed through the process chain /3/. The complexity of these data is the huge challenge for the data handling. Because of the asymmetrical and 3-dimensional surfaces of freeforms, large data volumes have to be created, trimmed, extended and fitted. All these processes must be performed without losing the accuracy of the original design data. Additionally, manifold types of geometries results in different kinds of mathematical representations of freeform surfaces and furthermore the used CAD/CAM tools are dealing with a set of spatial transport formats. These are all reasons why manufacture-oriented approaches for the freeform data handling are not yet sufficiently developed. This paper suggests a classification of freeform surfaces based on the manufacturing methods which are offered by diamond machining. The different manufacturing technologies, ranging from servo-turning to shaping, require a differentiated approach for the data handling process. The usage of analytical descriptions in form of splines and polynomials as well as the application of discrete descriptions like point clouds is shown in relation to the previously made classification. Advantages and disadvantages of freeform representations are discussed. Aspects of the data handling in between different process steps are pointed out and suitable exchange formats for freeform data are proposed. The described approach offers the possibility for efficient data handling from optical

  13. Experience of handling beryllium, tritium and activated components from JET ITER like wall

    Science.gov (United States)

    Widdowson, A.; Baron-Wiechec, A.; Batistoni, P.; Belonohy, E.; Coad, J. P.; Dinca, P.; Flammini, D.; Fox, F.; Heinola, K.; Jepu, I.; Likonen, J.; Lilley, S.; Lungu, C. P.; Matthews, G. F.; Naish, J.; Pompilian, O.; Porosnicu, C.; Rubel, M.; Villari, R.; Contributors, JET

    2016-02-01

    JET components are removed periodically for surface analysis to assess material migration and fuel retention. This paper describes issues related to handling JET components and procedures for preparing samples for analysis; in particular a newly developed procedure for cutting beryllium tiles is presented. Consideration is also given to the hazards likely due to increased tritium inventory and material activation from 14 MeV neutrons following the planned TT and DT operations (DTE2) in 2017. Conclusions are drawn as to the feasibility of handling components from JET post DTE2.

  14. A Smartphone Controlled Handheld Microfluidic Liquid Handling System

    CERN Document Server

    Li, Baichen; Guan, Allan; Dong, Quan; Ruan, Kangcheng; Hu, Ronggui; Li, Zhenyu

    2014-01-01

    Microfluidics and lab-on-a-chip technologies have made it possible to manipulate small volume liquids with unprecedented resolution, automation and integration. However, most current microfluidic systems still rely on bulky off-chip infrastructures such as compressed pressure sources, syringe pumps and computers to achieve complex liquid manipulation functions. Here, we present a handheld automated microfluidic liquid handling system controlled by a smartphone, which is enabled by combining elastomeric on-chip valves and a compact pneumatic system. As a demonstration, we show that the system can automatically perform all the liquid handling steps of a bead-based sandwich immunoassay on a multi-layer PDMS chip without any human intervention. The footprint of the system is 6 by 10.5 by 16.5cm, and the total weight is 829g including battery. Powered by a 12.8V 1500mAh Li battery, the system consumed 2.2W on average during the immunoassay and lasted for 8.7 hrs. This handheld microfluidic liquid handling platform...

  15. Fusion reactor handling operations with cable-driven parallel robots

    Energy Technology Data Exchange (ETDEWEB)

    Izard, Jean-Baptiste, E-mail: jeanbaptiste.izard@tecnalia.com; Michelin, Micael; Baradat, Cédric

    2015-10-15

    Highlights: • CDPR allow 6DOF positioning of loads using cable as links without payload swag. • Conceptual design of a CDPR for carrying and positioning tokamak sectors is given. • A CDPR for threading stellarator coils (6D trajectory following) is provided. • Both designs are capable of fullfilling the required precision without tooling. - Abstract: Cable-driven parallel robots (CDPR) are in their concept cranes with inclined cables which allow control of all the degrees of freedom of its payload, and therefore stability of all the degrees of freedom, including rotations. The workspace of a CDPR is only limited by the length of the cables, and the payload capacity related to the mass of the whole robot is very important. Besides, the control being based on kinematic models, the behavior of a CDPR is really that of a robot capable of automated trajectories or remote handling. The present paper gives a presentation of two use case studies based on some of the assembly phases and remote handling actions as designed for the recent fusion machines. Based on the use cases already in place in fusion reactor baselines, the opportunity of using CDPR for assembly of structural elements and coils is discussed. Finally, prospects for remote handling equipment from the reactor in hot cells are envisioned based on current CDPR research.

  16. Occlusion Handling in Videos Object Tracking: A Survey

    Science.gov (United States)

    Lee, B. Y.; Liew, L. H.; Cheah, W. S.; Wang, Y. C.

    2014-02-01

    issues related to occlusion handling including the use of appropriate selection of motion models, image features and use of multiple cameras.

  17. Oxygen Handling and Cooling Options in High Temperature Electrolysis Plants

    Energy Technology Data Exchange (ETDEWEB)

    Manohar S. Sohal; J. Stephen Herring

    2008-07-01

    Idaho National Laboratory is working on a project to generate hydrogen by high temperature electrolysis (HTE). In such an HTE system, safety precautions need to be taken to handle high temperature oxygen at ~830°C. This report is aimed at addressing oxygen handling in a HTE plant.. Though oxygen itself is not flammable, most engineering material, including many gases and liquids, will burn in the presence of oxygen under some favorable physicochemical conditions. At present, an absolute set of rules does not exist that can cover all aspects of oxygen system design, material selection, and operating practices to avoid subtle hazards related to oxygen. Because most materials, including metals, will burn in an oxygen-enriched environment, hazards are always present when using oxygen. Most materials will ignite in an oxygen-enriched environment at a temperature lower than that in air, and once ignited, combustion rates are greater in the oxygen-enriched environment. Even many metals, if ignited, burn violently in an oxygen-enriched environment. However, these hazards do not preclude the operations and systems involving oxygen. Oxygen can be safely handled and used if all the materials in a system are not flammable in the end-use environment or if ignition sources are identified and controlled. In fact, the incidence of oxygen system fires is reported to be low with a probability of about one in a million. This report is a practical guideline and tutorial for the safe operation and handling of gaseous oxygen in high temperature electrolysis system. The intent is to provide safe, practical guidance that permits the accomplishment of experimental operations at INL, while being restrictive enough to prevent personnel endangerment and to provide reasonable facility protection. Adequate guidelines are provided to govern various aspects of oxygen handling associated with high temperature electrolysis system to generate hydrogen. The intent here is to present acceptable

  18. Handling and Emplacement Options for Deep Borehole Disposal Conceptual Design.

    Energy Technology Data Exchange (ETDEWEB)

    Cochran, John R. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Hardin, Ernest [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2015-07-01

    This report presents conceptual design information for a system to handle and emplace packages containing radioactive waste, in boreholes 16,400 ft deep or possibly deeper. Its intended use is for a design selection study that compares the costs and risks associated with two emplacement methods: drill-string and wireline emplacement. The deep borehole disposal (DBD) concept calls for siting a borehole (or array of boreholes) that penetrate crystalline basement rock to a depth below surface of about 16,400 ft (5 km). Waste packages would be emplaced in the lower 6,560 ft (2 km) of the borehole, with sealing of appropriate portions of the upper 9,840 ft (3 km). A deep borehole field test (DBFT) is planned to test and refine the DBD concept. The DBFT is a scientific and engineering experiment, conducted at full-scale, in-situ, without radioactive waste. Waste handling operations are conceptualized to begin with the onsite receipt of a purpose-built Type B shipping cask, that contains a waste package. Emplacement operations begin when the cask is upended over the borehole, locked to a receiving flange or collar. The scope of emplacement includes activities to lower waste packages to total depth, and to retrieve them back to the surface when necessary for any reason. This report describes three concepts for the handling and emplacement of the waste packages: 1) a concept proposed by Woodward-Clyde Consultants in 1983; 2) an updated version of the 1983 concept developed for the DBFT; and 3) a new concept in which individual waste packages would be lowered to depth using a wireline. The systems described here could be adapted to different waste forms, but for design of waste packaging, handling, and emplacement systems the reference waste forms are DOE-owned high- level waste including Cs/Sr capsules and bulk granular HLW from fuel processing. Handling and Emplacement Options for Deep Borehole Disposal Conceptual Design July 23, 2015 iv ACKNOWLEDGEMENTS This report has

  19. [Responsibilities of enterprises introducing new dangerous chemical substances and preparations].

    Science.gov (United States)

    Cieśla, Jacek; Majka, Jerzy

    2004-01-01

    The paper reviews the responsibilities of producers, importers and distributors set in a new Act of January 2001 on chemical substances and preparations (Off. J. 2001, No. 11, item 84, with subsequent amendments). This Act together with executive provisions is aimed at harmonizing Polish legislation with EU requirements. The Act sets conditions, restriction and bans of production placing on the market and use of chemical substances and preparations in order to protect human health and environment against their harmful effects. The Act together with a number of executive provisions render those who introduce dangerous chemicals and chemical preparations, including distributors responsible for: classification and labelling of dangerous chemical substances and preparations; possessing, making available and up-dating safety data sheets; supplying packages containing certain dangerous substances with child-proof fastenings; notifying the Inspector for Chemical Substances and Preparations about placing a dangerous preparation on the market; notifying the Inspector about a new substance and conducting required studies; being properly qualified to handle dangerous substances. The Act strictly defines the term "placing a substance or a preparation on the market"--it means making a substance or a preparation available to third parties on the territory of The Republic of Poland, territories of the Member States of the European Union or the territory of Iceland, Liechtenstein and Norway, unless the Act provides otherwise; it also means introduction of a substance or a preparation from outside of the territory referred to above on the customs territory of The Republic of Poland, or that of the member states of the European Union and other states listed above. In addition, some of the responsibilities defined by the provisions of the law on chemical substances and preparations are also applicable to handling of biocidals, which are classified as dangerous substances. The Act

  20. A Knowledge-Based Approach for Selection of Material Handling Equipment and Material Handling System Pre-design

    OpenAIRE

    YAMAN, Ramazan

    2001-01-01

    For material handling system design, material handling equipment selection is the first stage. Also the material handling system and facility layout design problems are coupled. Solving these problems needs consideration of these three different problems. Right material handling equipment selection and good design of the material handling system and facility layout can increase productivity and reduce investments and operations' costs. In this study, after describing the m...

  1. Microbiological risk assessment models for partitioning and mixing during food handling.

    Science.gov (United States)

    Nauta, Maarten J

    2005-04-15

    To describe the transmission dynamics of a pathogen over a food pathway in quantitative microbiological risk assessment (QMRA), several types of processes need to be modelled. Next to microbial processes like bacterial growth and inactivation, four food handling processes can be identified. Among these are partitioning and mixing of the food product. With these processes, the (sizes of) units of food product are modified and the pathogenic cells are reallocated over the units, so that the prevalence of contaminated units and the number of cells per unit may change. Usually, simple models of these processes are applied in QMRA food chain models. These models assume independence of units, random homogeneous distribution of cells (for partitioning) and equal contribution of units (for mixing), which is often not realistic in food and food handling processes. In this paper, these assumptions are abandoned. The use of multivariate distributions is proposed to include the effect of dependence between units: the Multinomial distribution for partitioning and the Dirichlet distribution for mixing. Effects of cell clustering and/or unequal sizes of units formed by partitioning or contributing to mixing are incorporated. Some algorithms are derived that are easily implemented in spreadsheet models that simulate food production and preparation. Some examples show the effect of more realistic modelling by implementation of these algorithms on the prevalence and the probability distribution of the number of pathogens per unit of food product. In general, cell clustering will result in lower prevalences, but higher levels of contamination in contaminated food units. With the methods presented, these effects can be quantified. Difficulties in estimating the model parameters and the impact of implementation of the proposed methods on risk estimates in QMRA are discussed.

  2. Handling Practices of Fresh Leafy Greens in Restaurants: Receiving and Training†

    Science.gov (United States)

    COLEMAN, ERIK; DELEA, KRISTIN; EVERSTINE, KAREN; REIMANN, DAVID; RIPLEY, DANNY

    2015-01-01

    Multiple foodborne illness outbreaks have been associated with the consumption of fresh produce. Investigations have indicated that microbial contamination throughout the farm-to-fork continuum often contributed to these outbreaks. Researchers have hypothesized that handling practices for leafy greens in restaurants may support contamination by and proliferation and amplification of pathogens that cause foodborne illness outbreaks. However, limited data are available on how workers handle leafy greens in restaurants. The purpose of this study was to collect descriptive data on handling practices of leafy greens in restaurants, including restaurant characteristics, types of leafy greens used, produce receipt, and food safety training and certification. As a federal collaborative partner with the Environmental Health Specialists Network (EHS-Net) of the Centers for Disease Control and Prevention, the U.S. Food and Drug Administration (FDA) recommended that EHS-Net participants survey handling practices for leafy greens in restaurants. The recommendations in the FDA’s Guide to Minimize Microbial Food Safety Hazards of Leafy Greens are significant to this study for comparison of the results. The survey revealed that appropriate handling procedures assist in the mitigation of other unsafe handling practices for leafy greens. These results are significant because the FDA guidance for the safe handling of leafy greens was not available until 2009, after the survey had been completed. The information provided from this study can be used to promote additional efforts that will assist in developing interventions to prevent future foodborne illness outbreaks associated with leafy greens. PMID:24290691

  3. Analysis of aircraft longitudinal handling qualities

    Science.gov (United States)

    Hess, R. A.

    1981-01-01

    The optimal control model (OCM) of the human pilot is applied to the study of aircraft handling qualities. Attention is focused primarily on longitudinal tasks. The modeling technique differs from previous applications of the OCM in that considerable effort is expended in simplifying the pilot/vehicle analysis. After briefly reviewing the OCM, a technique for modeling the pilot controlling higher order systems is introduced. Following this, a simple criterion for determining the susceptibility of an aircraft to pilot induced oscillations (PIO) is formulated. Finally, a model-based metric for pilot rating prediction is discussed. The resulting modeling procedure provides a relatively simple, yet unified approach to the study of a variety of handling qualities problems.

  4. Energy efficiency in air handling applications

    Energy Technology Data Exchange (ETDEWEB)

    Fontaine, P. [Australian Baldor (Australia)

    1995-07-01

    It is estimated that the cost of air handling in a typical office building is $25,000 to $60,000 per 10,000 sq metres. New technologies are now available to reduce this by 50 percent with an investment that is recoverable within two years. Old systems of air handling operated at full speed with flow rates changed by mechanical vanes or dampers. The excess capacity generated is wasting energy which could be saved using modern motor controls that match the system output with actual needs. Comparisons of relative energy consumptions of different fan flow control methods show that the more time a system spends throttled down, the better candidate it is for the more efficient Variable Speed Drive (VSD) device which matches the motor`s speed to actual needs. The use of VSD instead of vanes and dampers reduces operating costs which impacts directly on profitability. 2 tables, 1 fig.

  5. Handling System for Iridium-192 Seeds

    Science.gov (United States)

    Carpenter, W.; Wodicka, D.

    1973-01-01

    A complete system is proposed for safe handling of iridium-192 seeds used to internally irradiate malignant growths. A vibratory hopper feeds the seeds onto a transport system for deposit in a magazine or storage area. A circular magazine consisting of segmented plastic tubing with holes in the walls to accommodate the seeds seems feasible. The magazine is indexed to stop and release a seed for calibration and deposition.

  6. Browsing TAP Services with TapHandle

    Science.gov (United States)

    Louys, M.; Michel, L.; Mantelet, G.; Bonnarel, F.

    2012-09-01

    TapHandle is a Web application merging multiple services based on the IVOA Table Access Protocol (TAP) in one page. TAP resources are presented in an expandable tree whose leaves represent SQL tables. Both table description and content can be immediately displayed. A smart ADQL editor helps to setup queries on one table. A shopping cart facility allows users to get data of interest. A filter enriches the data layout with anchors pointing to remote services.

  7. Statistical methods for handling incomplete data

    CERN Document Server

    Kim, Jae Kwang

    2013-01-01

    ""… this book nicely blends the theoretical material and its application through examples, and will be of interest to students and researchers as a textbook or a reference book. Extensive coverage of recent advances in handling missing data provides resources and guidelines for researchers and practitioners in implementing the methods in new settings. … I plan to use this as a textbook for my teaching and highly recommend it.""-Biometrics, September 2014

  8. Development of spent fuel remote handling technology

    Energy Technology Data Exchange (ETDEWEB)

    Yoon, Ji Sup; Park, B. S.; Park, Y. S.; Oh, S. C.; Kim, S. H.; Cho, M. W.; Hong, D. H

    1997-12-01

    Since the nation`s policy on spent fuel management is not finalized, the technical items commonly required for safe management and recycling of spent fuel - remote technologies of transportation, inspection, maintenance, and disassembly of spent fuel - are selected and pursued. In this regards, the following R and D activities are carried out : collision free transportation of spent fuel assembly, mechanical disassembly of spent nuclear fuel and graphical simulation of fuel handling / disassembly process. (author). 36 refs., 16 tabs., 77 figs

  9. Including Assistive Technology in Teacher Preparation: Exploring One Approach

    Science.gov (United States)

    Poel, Elissa Wolfe; Wood, Jackie; Schmidt, Naomi

    2013-01-01

    Assistive Technology (AT) is specifically addressed in the most recent reauthorization of IDEA, the Individuals with Disabilities Education Improvement Act (2004). The law insures that assistive devices and services

  10. D0 data handling operational experience

    Energy Technology Data Exchange (ETDEWEB)

    Lee Lueking et al.

    2003-08-11

    We report on the production experience of the D0 experiment at the Fermilab Tevatron, using the SAM data handling system with a variety of computing hardware configurations, batch systems, and mass storage strategies. We have stored more than 300 TB of data in the Fermilab Enstore mass storage system. We deliver data through this system at an average rate of more than 2 TB/day to analysis programs, with a substantial multiplication factor in the consumed data through intelligent cache management. We handle more than 1.7 Million files in this system and provide data delivery to user jobs at Fermilab on four types of systems: a reconstruction farm, a large SMP system, a Linux batch cluster, and a Linux desktop cluster. In addition, we import simulation data generated at 6 sites worldwide, and deliver data to jobs at many more sites. We describe the scope of the data handling deployment worldwide, the operational experience with this system, and the feedback of that experience.

  11. Improving Memory Error Handling Using Linux

    Energy Technology Data Exchange (ETDEWEB)

    Carlton, Michael Andrew [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Blanchard, Sean P. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Debardeleben, Nathan A. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2014-07-25

    As supercomputers continue to get faster and more powerful in the future, they will also have more nodes. If nothing is done, then the amount of memory in supercomputer clusters will soon grow large enough that memory failures will be unmanageable to deal with by manually replacing memory DIMMs. "Improving Memory Error Handling Using Linux" is a process oriented method to solve this problem by using the Linux kernel to disable (offline) faulty memory pages containing bad addresses, preventing them from being used again by a process. The process of offlining memory pages simplifies error handling and results in reducing both hardware and manpower costs required to run Los Alamos National Laboratory (LANL) clusters. This process will be necessary for the future of supercomputing to allow the development of exascale computers. It will not be feasible without memory error handling to manually replace the number of DIMMs that will fail daily on a machine consisting of 32-128 petabytes of memory. Testing reveals the process of offlining memory pages works and is relatively simple to use. As more and more testing is conducted, the entire process will be automated within the high-performance computing (HPC) monitoring software, Zenoss, at LANL.

  12. Handle-attachments from nubia. A note

    Directory of Open Access Journals (Sweden)

    William CULICAN

    2009-10-01

    Full Text Available Information on the distinctive bronze handle - attachments in the shape of a pair of human hands has been painstakingly collected by Dr. E. Cuadrado in his Refertorio de los Recipientes Rituales metálicos con "Asas de Manos" de la Península Ibérica (Trabajos de Prehistoria XXI, Madrid 1966. There is little room to doubt that metal vessels with this form of handle, whether we regard them as braziers (braserillos in the older terminology or 'ritual vessels' as does Cuadrado, are related to the distribution of Phoenician or Punic trade and influence in the Iberian peninsula. The southerly 'Tartessian' distribution speaks for itself; for the western 'Levantine' distribution (from Murcia, Alicante, Valencia, Teruel, Tarragona, Málaga, Ibiza we can postulate Ibiza, Málaga or Cartagena as a probable distribution centre. The examples in the west central meseta (Sanchorreja, El Berrueco, La Osera come as no surprise in view of the fact that such obviously Phoenician objects as the Sanchorreja belt-buckle, the Berrueco bronzes reached the regions of Avila and Salamanca respectively. Even for the outlying spot on the hand-handle distribution map at Santa Olaya, the cèltic oppidum at the mouth of the River Mondego, a context of Phoenician trade is likely, since pottery of Carmona and later types was found there and is now in the museum at Figueira da Foz.

  13. SITE GENERATED RADIOLOGICAL WASTE HANDLING SYSTEM DESCRIPTION DOCUMENT

    Energy Technology Data Exchange (ETDEWEB)

    S. C. Khamankar

    2000-06-20

    The Site Generated Radiological Waste Handling System handles radioactive waste products that are generated at the geologic repository operations area. The waste is collected, treated if required, packaged for shipment, and shipped to a disposal site. Waste streams include low-level waste (LLW) in solid and liquid forms, as-well-as mixed waste that contains hazardous and radioactive constituents. Liquid LLW is segregated into two streams, non-recyclable and recyclable. The non-recyclable stream may contain detergents or other non-hazardous cleaning agents and is packaged for shipment. The recyclable stream is treated to recycle a large portion of the water while the remaining concentrated waste is packaged for shipment; this greatly reduces the volume of waste requiring disposal. There will be no liquid LLW discharge. Solid LLW consists of wet solids such as ion exchange resins and filter cartridges, as-well-as dry active waste such as tools, protective clothing, and poly bags. Solids will be sorted, volume reduced, and packaged for shipment. The generation of mixed waste at the Monitored Geologic Repository (MGR) is not planned; however, if it does come into existence, it will be collected and packaged for disposal at its point of occurrence, temporarily staged, then shipped to government-approved off-site facilities for disposal. The Site Generated Radiological Waste Handling System has equipment located in both the Waste Treatment Building (WTB) and in the Waste Handling Building (WHB). All types of liquid and solid LLW are processed in the WTB, while wet solid waste from the Pool Water Treatment and Cooling System is packaged where received in the WHB. There is no installed hardware for mixed waste. The Site Generated Radiological Waste Handling System receives waste from locations where water is used for decontamination functions. In most cases the water is piped back to the WTB for processing. The WTB and WHB provide staging areas for storing and shipping LLW

  14. Uranium hexafluoride: Safe handling, processing, and transporting: Conference proceedings

    Energy Technology Data Exchange (ETDEWEB)

    Strunk, W.D.; Thornton, S.G. (eds.)

    1988-01-01

    This conference seeks to provide a forum for the exchange of information and ideas of the safety aspects and technical issue related to the handling of uranium hexafluoride. By allowing operators, engineers, scientists, managers, educators, and others to meet and share experiences of mutual concern, the conference is also intended to provide the participants with a more complete knowledge of technical and operational issues. The topics for the papers in the proceedings are widely varied and include the results of chemical, metallurgical, mechanical, thermal, and analytical investigations, as well as the developed philosophies of operational, managerial, and regulatory guidelines. Papers have been entered individually into EDB and ERA. (LTN)

  15. DNA-Templated Introduction of an Aldehyde Handle in Proteins

    DEFF Research Database (Denmark)

    Kodal, Anne Louise Bank; Rosen, Christian Bech; Mortensen, Michael Rosholm;

    2016-01-01

    -templated reductive amination we create DNA-protein conjugates with control over labeling stoichiometry without genetic engineering. A guiding DNA strand with a metal-binding functionality facilitates site-selectivity by directing coupling of a second reactive DNA strand to the vicinity of a protein metal......-binding site. Here, we demonstrate DNA-templated reductive amination for His6-tagged proteins and native metal-binding proteins, including IgG1 antibodies. We also use a cleavable linker between the DNA and the protein to remove the DNA and introduce a single aldehyde to proteins. This functions as a handle...

  16. Storage and handling of blood components – perspectives.

    Science.gov (United States)

    Hervig, Tor; Kaada, Silje; Seghatchian, Jerard

    2014-10-01

    The storage and handling conditions of cellular blood components and plasma are often rigorous, which is causing extensive discard of components that may be of acceptable quality as the rules for “out of optimal storage conditions” seem to be based more on tradition than scientific investigations. This short review summarizes some of the key papers indicating that it should be time for reconsideration of these rules, and some new suggestions are carefully indicated. Red cell concentrates, platelet concentrates and FFP are considered;lyophilized plasma and never-frozen liquid plasma are not included in this paper.

  17. Sequence Handling by Sequence Analysis Toolbox v1.0

    DEFF Research Database (Denmark)

    Ingrell, Christian Ravnsborg; Matthiesen, Rune; Jensen, Ole Nørregaard

    2006-01-01

    The fact that mass spectrometry have become a high-throughput method calls for bioinformatic tools for automated sequence handling and prediction. For efficient use of bioinformatic tools, it is important that these tools are integrated or interfaced with each other. The purpose of sequence...... analysis toolbox v1.0 was to have a general purpose sequence analyzing tool that can import sequences obtained by high-throughput sequencing methods. The program includes algorithms for calculation or prediction of isoelectric point, hydropathicity index, transmembrane segments, and glycosylphosphatidyl...

  18. A Mars Sample Return Sample Handling System

    Science.gov (United States)

    Wilson, David; Stroker, Carol

    2013-01-01

    We present a sample handling system, a subsystem of the proposed Dragon landed Mars Sample Return (MSR) mission [1], that can return to Earth orbit a significant mass of frozen Mars samples potentially consisting of: rock cores, subsurface drilled rock and ice cuttings, pebble sized rocks, and soil scoops. The sample collection, storage, retrieval and packaging assumptions and concepts in this study are applicable for the NASA's MPPG MSR mission architecture options [2]. Our study assumes a predecessor rover mission collects samples for return to Earth to address questions on: past life, climate change, water history, age dating, understanding Mars interior evolution [3], and, human safety and in-situ resource utilization. Hence the rover will have "integrated priorities for rock sampling" [3] that cover collection of subaqueous or hydrothermal sediments, low-temperature fluidaltered rocks, unaltered igneous rocks, regolith and atmosphere samples. Samples could include: drilled rock cores, alluvial and fluvial deposits, subsurface ice and soils, clays, sulfates, salts including perchlorates, aeolian deposits, and concretions. Thus samples will have a broad range of bulk densities, and require for Earth based analysis where practical: in-situ characterization, management of degradation such as perchlorate deliquescence and volatile release, and contamination management. We propose to adopt a sample container with a set of cups each with a sample from a specific location. We considered two sample cups sizes: (1) a small cup sized for samples matching those submitted to in-situ characterization instruments, and, (2) a larger cup for 100 mm rock cores [4] and pebble sized rocks, thus providing diverse samples and optimizing the MSR sample mass payload fraction for a given payload volume. We minimize sample degradation by keeping them frozen in the MSR payload sample canister using Peltier chip cooling. The cups are sealed by interference fitted heat activated memory

  19. Optical modulator including grapene

    Energy Technology Data Exchange (ETDEWEB)

    Liu, Ming; Yin, Xiaobo; Zhang, Xiang

    2016-06-07

    The present invention provides for a one or more layer graphene optical modulator. In a first exemplary embodiment the optical modulator includes an optical waveguide, a nanoscale oxide spacer adjacent to a working region of the waveguide, and a monolayer graphene sheet adjacent to the spacer. In a second exemplary embodiment, the optical modulator includes at least one pair of active media, where the pair includes an oxide spacer, a first monolayer graphene sheet adjacent to a first side of the spacer, and a second monolayer graphene sheet adjacent to a second side of the spacer, and at least one optical waveguide adjacent to the pair.

  20. Visual Impairment, Including Blindness

    Science.gov (United States)

    ... Who Knows What? Survey Item Bank Search for: Visual Impairment, Including Blindness Links updated, April 2017 En ... doesn’t wear his glasses. Back to top Visual Impairments in Children Vision is one of our ...

  1. Ergonomic design criteria for a novel laparoscopic tool handle with tactile feedback.

    Science.gov (United States)

    Mårvik, R; Nesbakken, R; Langø, T; Yavuz, Y; Vanhauwaert Bjelland, H; Ottermo, M V; Stavdahl, O

    2006-10-01

    Laparoscopic surgery has many ergonomic disadvantages often not considered in the design of instruments. The poorly designed surgical tools produce inconveniences in both functional and cognitive aspects; including tactile sensation and visual-motor space coordination. The aim of this article is to find out how laparoscopic handle design can be improved by combining classical ergonomic guidelines with tactile feedback related to handle design. The article briefly discusses how the human hand and hand-held tools are used to perform tasks. An ergonomic handle for laparoscopic grasping, with a built-in tactile sensation display, is presented. Our review of laparoscopic instruments reveals important aspects for handle design. It is concluded that there is a need for greater awareness of ergonomic guidelines for users' sensory requirements when designing and manufacturing laparoscopic instruments.

  2. Manual handling risks and controls in a soft drinks distribution centre.

    Science.gov (United States)

    Wright, E J; Haslam, R A

    1999-08-01

    This paper describes an investigation into manual handling risks and controls within a soft drinks distribution centre, presented as a case study regarding compliance with the requirements of the Manual Handling Operations Regulations 1992. Methods used included semi-structured interviews, document analysis, analysis of training, OWAS postural analysis and use of the NIOSH equation. Warehouse operators and delivery drivers were studied, and two methods of work compared involving pallets and cages. Significant differences were found between the two work methods with respect to harmful postures. Manual handling risks were found in both warehouse and delivery areas, some being classed as "excessive" using the NIOSH equation. As this company has a good safety record and considers itself proactive in the area of health and safety, the investigation raises concerns about how organisations have responded to the Manual Handling Operations Regulations.

  3. Flexible Electrostatic Technology for Capture and Handling Project

    Science.gov (United States)

    Keys, Andrew; Bryan, Tom; Horwitz, Chris; Rakoczy, John; Waggoner, Jason

    2015-01-01

    previous MSFC and NASA proposals or concepts can now be realized or simplified by the development of the this initial and future FETCH grippers including commercial resupply, Exploration vehicle assembly, Satellite servicing, and orbital debris removal since a major part of these missions is to align to and capture some handle. Completed Project (2013 - 2014) Flexible Electrostatic Technology for Capture & Handling Project Center Innovation Fund: MSFC CIF Program | Space Technology Mission Directorate (STMD) For more information visit techport.nasa.gov Some NASA technology projects are smaller (for example SBIR/STTR, NIAC and Center Innovation Fund), and will have less content than other, larger projects. Newly created projects may not sensors or injection of permanent adhesives. With gripping forces estimated between 0.5 and 2.5 pounds per square inch or 70-300 lb./sq. ft. of surface contact, the FETCH can turn-on and turn-off rapidly and repeatedly to enable sample handling, soft docking, in-space assembly, and precision relocation for accurate anchor adhesion.

  4. Conceptual design of a generic pulse schedule and event handling editor for improved fusion device operation

    Energy Technology Data Exchange (ETDEWEB)

    Barana, Oliviero, E-mail: oliviero.barana@cea.fr [CEA, IRFM, F-13108 Saint-Paul-Lez Durance (France); Nouailletas, Rémy; Brémond, Sylvain; Moreau, Philippe; Allegretti, Ludovic; Balme, Stéphane; Ravenel, Nathalie [CEA, IRFM, F-13108 Saint-Paul-Lez Durance (France); Mannori, Simone [ENEA C.R. Brasimone, 40032 Camugnano (Italy); Guillerminet, Bernard; Leroux, Fabrice; Douai, David; Nardon, Eric; Hertout, Patrick; Saint-Laurent, François [CEA, IRFM, F-13108 Saint-Paul-Lez Durance (France)

    2013-10-15

    Highlights: ► Real-time event handling requires extended functionalities of pulse schedule editors and plasma control systems ► A new pulse schedule editor, conceived for parameterization of systematic off-normal event handling, is described ► A global, generic approach on off-normal event handling is highlighted ► The functional architecture of an off-normal event handling oriented plasma control system is discussed ► The main objects of the pulse schedule editor are the segment-descriptor object and the scenario-descriptor object. -- Abstract: Coping with unexpected events is an important issue of nuclear fusion experiments. The future machines, characterized by very long plasma discharges and actively cooled metallic plasma-facing components, will require a systematic intervention in real time, in order to maximize the performance and protect the investment. The real-time management of events will require extending the functionalities of the current pulse schedule editors with the possibility of using reference waveforms provided with acceptability margins and setting up advanced mitigation strategies and event countermeasures. With this purpose, a new pulse schedule editor, based on a time-segment approach for the preparation of experimental scenarios, is being conceived on Tore Supra, together with a new plasma control system. This paper will report on their conceptual design and give account of the preliminary results of a feasibility study currently under way in order to prepare a possible implementation on Tore Supra.

  5. Habituating to handling: factors affecting preorbital gland opening in red deer calves.

    Science.gov (United States)

    Ceacero, F; Landete-Castillejos, T; Bartošová, J; García, A J; Bartoš, L; Komárková, M; Gallego, L

    2014-09-01

    The preorbital gland plays not only an olfactory role in cervids but also a visual one. Opening this gland is an easy way for the calf to communicate with the mother, indicating hunger/satiety, stress, pain, fear, or excitement. This information can be also useful for farm operators to assess how fast the calves habituate to handling routines and to detect those calves that do not habituate and may suffer chronic stress in the future. Thirty-one calves were subjected to 2 consecutive experiments to clarify if observing preorbital gland opening is related to habituation to handling in red deer calves (Cervus elaphus). Calves were born in 3 different paddocks, handled as newborns (Exp. 1), and then subjected to the same routine handling but with different periodicity: every 1, 2, or 3 wk (Exp. 2). In Exp. 1, preorbital gland opening was recorded in newborns during an initial handling (including weighing, ear tagging, and sex determination). Preorbital gland opening occurred in 93% of calves during this procedure and was not affected by sex, time since birth, or birth weight. Experiment 2 consisted of measuring preorbital opening during the same routine handling (weighing, blood sampling, and rump touching to assess body condition) when calves were 1, 3, and 5 mo old. Binary logistic regression showed that gland opening was associated with habituation to handling, since at 1 and 3 mo the probability of opening the gland decreased with the number of handlings that a calf experienced before (P = 0.008 and P = 0.028, respectively). However, there were no further changes in preorbital gland opening rate in the 5-mo-old calves (P = 0.182). The significant influence of the number of previous handlings on the probability of opening the preorbital gland was confirmed through generalized linear model with repeated measures (P = 0.007). Preorbital gland opening decreased along the phases of the study. Nevertheless, we found a significant trend in individuals to keep similar

  6. Solidex 86 - modern technology in bulk solids handling

    Energy Technology Data Exchange (ETDEWEB)

    1986-01-01

    A total of 30 papers were presented covering the following topics: coal and ash handling; dust control and explosion hazards; pneumatic conveying; mechanical conveying; storage and wear; and weighing technology and automated materials handling. 15 papers have been abstracted separately.

  7. 7 CFR 958.53 - Handling for specified purposes.

    Science.gov (United States)

    2010-01-01

    ... DESIGNATED COUNTIES IN IDAHO, AND MALHEUR COUNTY, OREGON Order Regulating Handling Regulation § 958.53..., in order to facilitate the handling of onions for the following purposes whenever he finds that to...

  8. Some factors to consider in handling and storing spent fuel

    Energy Technology Data Exchange (ETDEWEB)

    Bailey, W.J.

    1985-11-01

    This report includes information from various studies performed under the Wet Storage Task of the Behavior of Spent Fuel in Storage Project of the Commercial Spent Fuel Management (CSFM) Program at Pacific Northwest Laboratory. Wet storage experience has been summarized earlier in several other reports. This report summarizes pertinent items noted during FY 1985 concerning recent developments in the handling and storage of spent fuel and associated considerations. The subjects discussed include recent publications, findings, and developments associated with: (1) storage of water reactor spent fuel in water pools, (2) extended-burnup fuel, (3) fuel assembly reconstitution and reinsertion, (4) rod consolidation, (5) variations in the US Nuclear Regulatory Commission's definition of failed fuel, (6) detection of failed fuel rods, and (7) extended integrity of spent fuel. A list of pertinent publications is included.

  9. Concurrent projects: how many can you handle?

    Directory of Open Access Journals (Sweden)

    Steyn, Herman

    2015-11-01

    Full Text Available The number of projects a person can handle simultaneously is a relevant factor in strategic planning and in project portfolio management. Internationally the de facto standard seems to be that a person should not work on more than two or three projects simultaneously; but several factors could influence this figure. Empirical evidence indicates that, in some South African sectors, people tend to work on many more than two or three projects simultaneously. In this paper, factors that influence the number of projects a person can work on are identified so that they can be investigated in further studies. Some ideas about using key resources optimally are also presented.

  10. Vilkår for kollektiv handling

    DEFF Research Database (Denmark)

    Scheuer, Steen

    2014-01-01

    Fagbevægelsens situation og opgaver påvirkes af forandringer i de institutionelle makrostrukturer, som indebærer et øget fokus på lønrelativiteter og på at overvåge ens egen faggruppes eller erhvervsgruppes relative position i lønhierarkiet. Dette fokus er ikke nyt, men det er øget, og det er int...... serviceydelser, fagforeningerne oprindeligt blev sat i verden for at levere. Det er i disse ændrede vilkår for kollektive handling, i dette krydspres, at fagbevægelsen skal finde ny strategier og definere ny former for solidaritet...

  11. Enbridge system : crude types, transportation and handling systems

    Energy Technology Data Exchange (ETDEWEB)

    Anand, A. [Enbridge Corp., Edmonton, AB (Canada)

    2009-07-01

    The supply of crude oil from the Western Canada Sedimentary Basin is expected to increase by approximately 2.1 million barrels per day by 2015. The crudes that Enbridge handles range from 19 API to 40 API and 0.1 per cent sulphur to 4.7 per cent sulphur. The diverse supply of crude oil that the Enbridge system handles includes conventional heavy, synthetic heavy, heavy high tan, heavy low residual, medium, light sour, heavy sour, light sweet, light sweet synthetic, condensate and olefinic crudes. This presentation discussed Enbridge's plans for infrastructure expansion, crude types and quality assurance program. The company's infrastructure plans include the expansion of regional pipelines to bring more supplies to the mainline; expansion of the mainline capacity to existing markets; and providing pipeline access to new markets. Merchant storage terminals will be provided in some locations. The quality of various crude types will be maintained through judicious sequencing and tank bottoms crossings. tabs., figs.

  12. 7 CFR 905.8 - Prepare for market.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 8 2010-01-01 2010-01-01 false Prepare for market. 905.8 Section 905.8 Agriculture... TANGELOS GROWN IN FLORIDA Order Regulating Handling Definitions § 905.8 Prepare for market. Prepare for market means to wash, grade, size, or place fruit (whether or not wrapped) into any container...

  13. 76 FR 37118 - Manual Materials Handling (MMH) Workshop

    Science.gov (United States)

    2011-06-24

    ... HUMAN SERVICES Centers for Disease Control and Prevention Manual Materials Handling (MMH) Workshop... Health, will be holding a two-day Manual Materials Handling (MMH) Workshop. The Workshop is a National... engineering solutions for manual materials handling jobs in Retail, Wholesale and Warehouse industries....

  14. 30 CFR 77.606 - Energized trailing cables; handling.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Energized trailing cables; handling. 77.606... COAL MINES Trailing Cables § 77.606 Energized trailing cables; handling. Energized medium- and high-voltage trailing cables shall be handled only by persons wearing protective rubber gloves (see § 77.606-1...

  15. Execution Constraint Verification of Exception Handling on UML Sequence Diagrams

    NARCIS (Netherlands)

    Ciraci, S.; Sözer, Hasan; Aksit, Mehmet; Havinga, W.K.

    2011-01-01

    Exception handling alters the control flow of the program. As such, errors introduced in exception handling code may influence the overall program in undesired ways. To detect such errors early and thereby decrease the programming costs, it is worthwhile to consider exception handling at design

  16. 49 CFR 219.205 - Specimen collection and handling.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false Specimen collection and handling. 219.205 Section... § 219.205 Specimen collection and handling. (a) General. Urine and blood specimens must be obtained, marked, preserved, handled, and made available to FRA consistent with the requirements of this subpart...

  17. 9 CFR 114.11 - Storage and handling.

    Science.gov (United States)

    2010-01-01

    ... 9 Animals and Animal Products 1 2010-01-01 2010-01-01 false Storage and handling. 114.11 Section... BIOLOGICAL PRODUCTS § 114.11 Storage and handling. Biological products at licensed establishments shall be protected at all times against improper storage and handling. Completed product shall be kept under...

  18. 46 CFR 151.45-4 - Cargo-handling.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 5 2010-10-01 2010-10-01 false Cargo-handling. 151.45-4 Section 151.45-4 Shipping COAST... LIQUID HAZARDOUS MATERIAL CARGOES Operations § 151.45-4 Cargo-handling. (a) On a United States tank barge... the persons in charge of cargo handling. (h) Auxiliary steam, air, fuel, or electric current. When...

  19. 49 CFR 176.57 - Supervision of handling and stowage.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 2 2010-10-01 2010-10-01 false Supervision of handling and stowage. 176.57 Section 176.57 Transportation Other Regulations Relating to Transportation PIPELINE AND HAZARDOUS... VESSEL General Handling and Stowage § 176.57 Supervision of handling and stowage. (a) Hazardous...

  20. 30 CFR 75.817 - Cable handling and support systems.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Cable handling and support systems. 75.817... High-Voltage Longwalls § 75.817 Cable handling and support systems. Longwall mining equipment must be provided with cable-handling and support systems that are constructed, installed and maintained to...

  1. 7 CFR 923.322 - Washington cherry handling regulation.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 8 2010-01-01 2010-01-01 false Washington cherry handling regulation. 923.322 Section... CHERRIES GROWN IN DESIGNATED COUNTIES IN WASHINGTON Order Regulating Handling Grade, Size, Container and Pack Regulation § 923.322 Washington cherry handling regulation. (a) Grade. No handler shall...

  2. 77 FR 76815 - Handling of Animals; Contingency Plans

    Science.gov (United States)

    2012-12-31

    ... Animal and Plant Health Inspection Service 9 CFR Parts 2 and 3 RIN 0579-AC69 Handling of Animals... handling, care, treatment, and transportation of certain animals by dealers, research facilities... humane handling, care, treatment, and transportation of animals covered by the AWA. Currently, part 3...

  3. 46 CFR 154.1850 - Entering cargo handling spaces.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 5 2010-10-01 2010-10-01 false Entering cargo handling spaces. 154.1850 Section 154... cargo handling spaces. (a) The master shall ensure that the ventilation system under § 154.1200 is in... handling equipment. (b) The master shall ensure that a warning sign listing the requirement for use of the...

  4. Analytic device including nanostructures

    KAUST Repository

    Di Fabrizio, Enzo M.

    2015-07-02

    A device for detecting an analyte in a sample comprising: an array including a plurality of pixels, each pixel including a nanochain comprising: a first nanostructure, a second nanostructure, and a third nanostructure, wherein size of the first nanostructure is larger than that of the second nanostructure, and size of the second nanostructure is larger than that of the third nanostructure, and wherein the first nanostructure, the second nanostructure, and the third nanostructure are positioned on a substrate such that when the nanochain is excited by an energy, an optical field between the second nanostructure and the third nanostructure is stronger than an optical field between the first nanostructure and the second nanostructure, wherein the array is configured to receive a sample; and a detector arranged to collect spectral data from a plurality of pixels of the array.

  5. Modelling preparation and consumption of pork products

    DEFF Research Database (Denmark)

    Swart, Arno; Nauta, Maarten; Evers, Eric

    This poster describes the retail and consumer phase of the EFSA Salmonella in Pork QMRA (Quantitative Microbiological Risk Assessment, funded under an Article 36 grant to support the scientific opinion required by EFS). The food chain is modelled from retail to ingestion by the consumer. Three...... types of pork are considered: minced meat, pork cuts and dry cured sausages. This particular choice was made because each product represents a clear distinct hazard. Pork cuts are usually cooked well, but there is a chance of cross contamination during cutting and handling of the meat. Minced meat...... is thoroughly mixed, and Salmonellae may be present in the interior of hamburger patties, undercooking may occur, and Salmonellae may survive. Dry cured sausages, including all variations therein like chorizo, salami, etc., are eaten uncooked. Food preparation habits are highly variable and accurate data...

  6. Preparation and Characterisation of Exfoliated Graphene for Quantum Resistance Metrology

    NARCIS (Netherlands)

    Rietveld, G.; Elferen, H.J. van; Giesbers, A.J.M.; Veligura, A.; Zeitler, U.; Novoselov, K.S.; Wees, B.J. van; Geim, A.K.; Maan, J.C.

    2010-01-01

    Exfoliated graphene samples have been prepared for use in quantum resistance metrology. Good progress is recently made in achieving contact resistances to graphene of less than 50 Ω. Details are presented on the handling and measurement of graphene samples.

  7. Microbiological quality and safe handling of enteral diets in a hospital in Minas Gerais, Brazil

    Directory of Open Access Journals (Sweden)

    Raquel Oliveira Medrado Pinto

    2015-06-01

    Full Text Available Contamination of enteral diets represents a high risk of compromising the patient's medical condition. To assess the microbiological quality and aseptic conditions in the preparation and administration of handmade and industrialized enteral diets offered in a hospital in the Valley of Jequitinhonha, MG, Brazil, we performed a microbiological analysis of 50 samples of diets and 27 samples of surfaces, utensils, and water used in the preparation of the diets. In addition, we assessed the good handling practices of enteral diets according to the requirements specified by the Brazilian legislation. Both kinds of enteral diets showed contamination by coliforms and Pseudomonas spp. No sample was positive for Staphylococcus aureus and Salmonella spp. On the other hand, Listeria spp. was detected in only one sample of handmade diets. Contamination was significantly higher in the handmade preparations (p < 0.05. Nonconformities were detected with respect to good handling practices, which may compromise the diet safety. The results indicate that the sanitary quality of the enteral diets is unsatisfactory, especially handmade diets. Contamination by Pseudomonas spp. is significant because it is often involved in infection episodes. With regard to aseptic practices, it was observed the need of implementing new procedures for handling enteral diets.

  8. LWR nuclear fuel bundle data for use in fuel bundle handling

    Energy Technology Data Exchange (ETDEWEB)

    Weihermiller, W.B.; Allison, G.S.

    1979-09-01

    Although increasing numbers of spent light water reactor (LWR) fuel bundles are moved into storage, no handling equipment is set up to manipulate all of the various types of fuel bundles. This report summarizes fuel bundle information of interest to the designer of such handling equipment. Dimensional descriptions are included with discussions of assembly procedure and manufacturer provisions for handling equipment. No attempt is made to make a complete compilation of dimensional information; the number of fuel bundle designs and design revisions makes it impractical. Because the fuel bundle designs are so varied, any equipment intended for handling all types of bundles will have to be designed with flexibility in mind. Besides the ability to manipulate fuel bundles in space, handling equipment may be required to locate an external surface or to position a cutting operation to avoid breaking a fuel rod pressure boundary. Even with the most sophisticated and flexible handling equipment, some situations will require use of the manufacturers' as-built descriptions of individual fuel bundles.

  9. The role of visualisation in data handling in Grade 9 within a problem-centred context

    Directory of Open Access Journals (Sweden)

    Antonia Makina

    2009-09-01

    Full Text Available In the recent past, data handling has been neglected at secondary school level, perhaps partially due to the strong emphasis on developing arithmetic, algebra and geometry. For the first time, the South African curriculum includes substantial amounts of data handling at all grade levels. The introduction of more data handling in the secondary school curriculum in South Africa and the prevalence of many problems in the teaching of probability and statistics argues for a serious reconsideration of the way it is taught to the pupils. Currently this concern has been the focus of a call for reform in mathematics education by a body like the National Council of Teachers of Mathematics (NCTM at all levels of schooling (NCTM, 1989; 2000. The importance of visualisation in mathematics, at all levels of mathematical problem solving is well documented in the literature (Bishop, 1989; Maher & Alston, 1989; Moses, 1982; Wheatley, 1991 but almost nothing was done to appreciate visualisation in the learning of data handling. The paper therefore provides a qualitative examination from a Masters dissertation (Makina, 2005 of the role of visualisation in the learning of data handling. This is done through examining the thought processes involved by Grade 9 learners during visualisation while solving data handling tasks. Several roles of visualisation were identified and most were found to improve the critical and creative thinking of pupils during their learning of data handling. The results show that learners are likely to improve their performance in data handling if the awareness of the need to use visualisation creatively as a tool for understanding are highlighted.

  10. Synthesis of capped RNA using a DMT group as a purification handle.

    Science.gov (United States)

    Veliath, Elizabeth; Gaffney, Barbara L; Jones, Roger A

    2014-01-01

    We report a new method for synthesis of capped RNA or 2'-OMe RNA that uses a N(2-)4,4'-dimethoxytrityl (DMT) group as a lipophilic purification handle to allow convenient isolation and purification of the capped RNA. The DMT group is easily removed under mild conditions without degradation of the cap. We have used this approach to prepare capped 10- and 20-mers. This method is compatible with the many condensation reactions that have been reported for preparation of capped RNA or cap analogues.

  11. Assessment of work-related accidents associated with waste handling in Belo Horizonte (Brazil).

    Science.gov (United States)

    Mol, Marcos Pg; Pereira, Amanda F; Greco, Dirceu B; Cairncross, Sandy; Heller, Leo

    2017-08-01

    As more urban solid waste is generated, managing it becomes ever more challenging and the potential impacts on the environment and human health also become greater. Handling waste - including collection, treatment and final disposal - entails risks of work accidents. This article assesses the perception of waste management workers regarding work-related accidents in domestic and health service contexts in Belo Horizonte, Brazil. These perceptions are compared with national data from the Ministry of Social Security on accidents involving workers in solid waste management. A high proportion of accidents involves cuts and puncture injuries; 53.9% among workers exposed to domestic waste and 75% among those exposed to health service waste. Muscular lesions and fractures accounted for 25.7% and 12.5% of accidents, respectively. Data from the Ministry of Social Security diverge from the local survey results, presumably owing to under-reporting, which is frequent in this sector. Greater commitment is needed from managers and supervisory entities to ensure that effective measures are taken to protect workers' health and quality of life. Moreover, workers should defend their right to demand an accurate registry of accidents to complement monitoring performed by health professionals trained in risk identification. This would contribute to the improved recovery of injured workers and would require managers in waste management to prepare effective preventive action.

  12. Nozzle extraction process and handlemeter for measuring handle

    Science.gov (United States)

    Alley, V. L., Jr.; Mchatton, A. D. (Inventor)

    1978-01-01

    Method and apparatus for quantitatively measuring the handle of fabrics and other flexible materials is presented. Handle is that term used to refer to the qualities of drapability, flexibility, compressibility, foldability, stretchability, pliability, etc., possessed by fabrics and other flexible materials. In the present invention the handle of a material sample is quantified by measuring the force required to draw the sample through an orifice and expressing the resultant extractive force as a function of test apparatus geometry and the amount of sample drawn through the orifice to arrive at quantitative measure of handle, to be defined as handle modulus, for the sample in question.

  13. Brief neonatal handling alters sexually dimorphic behaviors in adult rats.

    Science.gov (United States)

    Fujimoto, Tetsuya; Kubo, Kazuhiko; Nishikawa, Yasuo; Aou, Shuji

    2014-03-01

    Several effects of neonatal handling on brain and behavior have been reported. We investigated the effects of neonatal handling on behaviors that have been shown to be sexually dimorphic in rats using an open-field test. "Gender differences" were observed in locomotor activity, exploratory behavior and grooming in the handled group. However, clear gender differences in these behaviors were not observed in the non-handled group. Our findings show that brief daily handling sessions (~ 1 min) in the first 2 weeks of postnatal life increased locomotor activity and exploratory behavior, and that these effects were more pronounced in females. Moreover, many rats in the non-handling group exhibited an increase in defecation relative to the handling group during the 10-min observation period. This suggests that the non-handling group experienced more stress in response to the novel open-field arena, and that this resulted in the absence of gender differences. Notably, this anxiety-related response was attenuated by neonatal handling. Our study underscores the impact of brief neonatal handling on sexually dimorphic behaviors, and indicates that caution should be exercised in controlling for the effects of handling between experimental groups, particularly in neurotoxicological studies that evaluate gender differences.

  14. Copper handling by astrocytes: insights into neurodegenerative diseases.

    Science.gov (United States)

    Tiffany-Castiglioni, Evelyn; Hong, Sandra; Qian, Yongchang

    2011-12-01

    Copper (Cu) is an essential trace element in the brain that can be toxic at elevated levels. Cu accumulation is a suspected etiology in several neurodegenerative diseases, including Alzheimer's disease, Parkinson's disease, and prion-induced disorders. Astrocytes are a proposed depot in the brain for Cu and other metals, including lead (Pb). This article describes the physiological roles of Cu in the central nervous system and in selected neurodegenerative diseases, and reviews evidence that astrocytes accumulate Cu and protect neurons from Cu toxicity. Findings from murine genetic models of Menkes disease and from cell culture models concerning the molecular mechanisms by which astrocytes take up, store, and buffer Cu intracellularly are discussed, as well as potential mechanistic linkages between astrocyte functions in Cu handling and neurodegenerative diseases.

  15. Knowledge and attitude regarding mercury handling and disposal in students.

    Science.gov (United States)

    Patel, Shruti; Tiwari, Rajnarayan R; Murarka, Shiva; Kumar, Sunil

    2011-07-01

    The present cross-sectional study was carried out in higher secondary schools of the science specialty in Ahmedabad. A total of 653 students (196 taught in English, 395 taught in Gujarati and 62 taught in Hindi) from seven schools were included. The interview technique was used for data collection using a predesigned questionnaire. A total of 457 (70%) were boys and 196 (30%) were girls. About two-thirds of the study participants had handled mercury at sometime in their life and home was the common place where it was handled. More than half of the Hindi-taught students did not know about its physical appearance. The majority of the Gujarati-taught students knew that mercury is harmful to health whereas one-third of the English- and Hindi-taught students considered mercury to be harmless. A total of 46% of the Gujarati-taught and 44% of the English-taught students had encountered spilled mercury at sometime in their life and 21.6% of English-taught and 25% of Hindi-taught students had either smelled or played with spilled mercury. More than two-thirds of the English- and Hindi-taught students recommended the usual cleaning method whereas 81.8% of Gujarati-taught students suggested a special method should be used for the disposal of spilled mercury. The majority of the students did not know whether mercury could be substituted by a harmless substance.

  16. Integrated Payload Data Handling Systems Using Software Partitioning

    Science.gov (United States)

    Taylor, Alun; Hann, Mark; Wishart, Alex

    2015-09-01

    An integrated Payload Data Handling System (I-PDHS) is one in which multiple instruments share a central payload processor for their on-board data processing tasks. This offers a number of advantages over the conventional decentralised architecture. Savings in payload mass and power can be realised because the total processing resource is matched to the requirements, as opposed to the decentralised architecture here the processing resource is in effect the sum of all the applications. Overall development cost can be reduced using a common processor. At individual instrument level the potential benefits include a standardised application development environment, and the opportunity to run the instrument data handling application on a fully redundant and more powerful processing platform [1]. This paper describes a joint program by SCISYS UK Limited, Airbus Defence and Space, Imperial College London and RAL Space to implement a realistic demonstration of an I-PDHS using engineering models of flight instruments (a magnetometer and camera) and a laboratory demonstrator of a central payload processor which is functionally representative of a flight design. The objective is to raise the Technology Readiness Level of the centralised data processing technique by address the key areas of task partitioning to prevent fault propagation and the use of a common development process for the instrument applications. The project is supported by a UK Space Agency grant awarded under the National Space Technology Program SpaceCITI scheme. [1].

  17. Handling Qualities of a Capsule Spacecraft During Atmospheric Entry

    Science.gov (United States)

    Bilimoria, Karl D.; Mueller, Eric R.

    2010-01-01

    A piloted simulation was conducted to study handling qualities for capsule spacecraft entering the Earth s atmosphere. Eight evaluation pilots, including six pilot astronauts, provided Cooper-Harper ratings, workload ratings, and qualitative comments. The simulation began after descending through the atmospheric entry interface point and continued until the drogue parachutes deployed. There were two categories of piloting tasks, both of which required bank angle control. In one task category, the pilot followed a closed-loop bank angle command computed by the backup guidance system to manage g-loads during entry. In the other task category, the pilot used intuitive rules to determine the desired bank angle independently, based on an open-loop schedule of vertical speed, Mach, and total energy specified at several range-to-target gates along the entry trajectory. Pilots were able to accurately track the bank angle guidance commands and steered the capsule toward the recovery site with essentially the same range error as the benchmark autopilot trajectory albeit with substantially higher propellant usage, and the handling qualities for this task were satisfactory. Another key result was that the complex piloting task of atmospheric entry could be performed satisfactorily, even in the presence of large dispersions, by controlling bank angle to follow a simple open-loop schedule.

  18. Handling and Treatment of Poultry Hatchery Waste: A Review

    Directory of Open Access Journals (Sweden)

    Belinda Rodda

    2011-01-01

    Full Text Available A literature review was undertaken to identify methods being used to handle and treat hatchery waste. Hatchery waste can be separated into solid waste and liquid waste by centrifuging or by using screens. Potential methods for treating hatchery waste on site include use of a furnace to heat the waste to produce steam to run a turbine generator or to use an in line composter to stabilise the waste. There is also potential to use anaerobic digestion at hatcheries to produce methane and fertilisers. Hatcheries disposing wastewater into lagoons could establish a series of ponds where algae, zooplankton and fish utilise the nutrients using integrated aquaculture which cleans the water making it more suitable for irrigation. The ideal system to establish in a hatchery would be to incorporate separation and handling equipment to separate waste into its various components for further treatment. This would save disposal costs, produce biogas to reduce power costs at plants and produce a range of value added products. However the scale of operations at many hatcheries is too small and development of treatment systems may not be viable.

  19. Pathology handling of pancreatoduodenectomy specimens: Approaches and controversies

    Institute of Scientific and Technical Information of China (English)

    María; del; Carmen; Gómez-Mateo; Luis; Sabater-Ortí; Antonio; Ferrández-Izquierdo

    2014-01-01

    Pancreatic cancer, with a 5% 5-year survival rate, is the fourth leading cause of cancer death in Western countries. Unfortunately, only 20% of all patients benefit from surgical treatment. The need to prolong survival has prompted pathologists to develop improved protocols to evaluate pancreatic specimens and their surgical margins. Hopefully, the new protocols will provide clinicians with more powerful prognostic indicators and accurate information to guide their therapeutic decisions. Despite the availability of several guidelines for the handling and pathology reporting of duodenopancreatectomy specimens and their continual updating by expert pathologists, there is no consensus on basic issues such as surgical margins or the definition of incomplete excision(R1) of pancreatic ductal adenocarcinoma. This article reviews the problems and controversies that dealing with duodenopancreatectomy specimens pose to pathologists, the various terms used to define resection margins or infiltration, and reports. After reviewing the literature, including previous guidelines and based on our own experience, we present our protocol for the pathology handling of duodenopancreatectomy specimens.

  20. Implication of human handling on packaged sausage rolls during sale

    Directory of Open Access Journals (Sweden)

    Coolborn AKHARAIYI FRED

    2016-08-01

    Full Text Available In other to identify the implication of human handling of packaged sausage rolls after production, a microbiological safety evaluation was carried out on sausage rolls sold on street and in shops. Among the sausage rolls, gala purchased from street vendors has the highest bacterial load of 2.82 × 104 CFU/g and 4.3 × 106 spore/g of fungal load, followed by meaty with bacterial load of 1.71 × 104 CFU/g and fungal load of 1.6 × 105 spore/g and was least in rite sausage roll with 1.46 × 104 CFU/g and 1 × 105 spore/g bacterial and fungal loads respectively. Seventeen bacteria species were isolated from both street vended and shop sold sausage rolls, the isolates identified including: Bacillus cereus, Acinetobacter calcoaceticus, Alcaligenes faecalis, Citrobacter freundii, Klebsiella ozaenae, Staphylococcus epidermidis, Enterobacter aerogenes, Staphylococcus aureus, Aeromonas hydrophila, Plesiomonas shigelloides, Moraxella catarhalis, Bacillus substilis, Escherichia coli, Salmonella typhi, Aeromonas anaerogenes, Aerococcus viridans and Azomonas agilis. Five fungi species were isolated from street vended sausage rolls only. The fungal species are Penicillium notatum, Aspergillus parasiticus, Aspergillus flavus, Penicillium italicum and Gliocephalis spp. From this study, street vended samples have higher microbial contamination than shop sold sausage rolls due to improper handling during sales.

  1. National Environmental Policy Act Compliance Strategy for the Remote-Handled Low-level Waste Disposal Facility

    Energy Technology Data Exchange (ETDEWEB)

    Peggy Hinman

    2010-10-01

    The U.S. Department of Energy (DOE) needs to have disposal capability for remote-handled low level waste (LLW) generated at the Idaho National Laboratory (INL) at the time the existing disposal facility is full or must be closed in preparation for final remediation of the INL Subsurface Disposal Area in approximately the year 2017.

  2. Effects of Handling and Vehicle Injections on Adrenocorticotropic and Corticosterone Concentrations in Sprague–Dawley Compared with Lewis Rats

    Science.gov (United States)

    Deutsch-Feldman, Molly; Picetti, Roberto; Seip-Cammack, Katharine; Zhou, Yan; Kreek, Mary Jeanne

    2015-01-01

    The hypothalamic–pituitary–adrenal (HPA) axis is a key factor in the trajectory of the addiction-like cycle (a pattern of behavior characterized by escalating drug use, withdrawal, and relapse) in preclinical and clinical studies. Concentrations of HPA hormones change in laboratory animals in response to standard experimental procedures, including handling and vehicle injections. We compared HPA activity in adult male Lewis (inbred) and Sprague–Dawley (outbred) rats, 2 common strains in rodent models of addiction, after different schedules of handling and saline injections, to explore the extent to which HPA responses differ by strain and whether interindividual differences underlie addiction vulnerability. The 4 treatment conditions were no, short, or long handling and saline injections. In handled groups, rats were handled for 1 to 2 min for 3 times daily and were euthanized after 7 d (short handling) or 14 d (long handling). The injection schedule in the saline injection group mimicked that in a model of binge-like cocaine exposure. Across all treatment groups, concentrations of adrenocorticotropic hormone were higher in Sprague–Dawley than in Lewis rats. In Sprague–Dawley rats, corticosterone concentrations decreased after continued handling but remained constant in Lewis rats. Interindividual variability in hormone levels was greater in Sprague–Dawley than Lewis rats, although corticosterone variability decreased after continued handling. Prolactin did not differ between groups of either Sprague–Dawley and Lewis rats before or after handling. This study underscores the importance of prolonged handling before experimenter-provided drug-administration paradigms and of strain-associated differences that may affect study outcomes. PMID:25651089

  3. Effects of handling and vehicle injections on adrenocorticotropic and corticosterone concentrations in Sprague-Dawley compared with Lewis rats.

    Science.gov (United States)

    Deutsch-Feldman, Molly; Picetti, Roberto; Seip-Cammack, Katharine; Zhou, Yan; Kreek, Mary Jeanne

    2015-01-01

    The hypothalamic-pituitary-adrenal (HPA) axis is a key factor in the trajectory of the addiction-like cycle (a pattern of behavior characterized by escalating drug use, withdrawal, and relapse) in preclinical and clinical studies. Concentrations of HPA hormones change in laboratory animals in response to standard experimental procedures, including handling and vehicle injections. We compared HPA activity in adult male Lewis (inbred) and Sprague-Dawley (outbred) rats, 2 common strains in rodent models of addiction, after different schedules of handling and saline injections, to explore the extent to which HPA responses differ by strain and whether interindividual differences underlie addiction vulnerability. The 4 treatment conditions were no, short, or long handling and saline injections. In handled groups, rats were handled for 1 to 2 min for 3 times daily and were euthanized after 7 d (short handling) or 14 d (long handling). The injection schedule in the saline injection group mimicked that in a model of binge-like cocaine exposure. Across all treatment groups, concentrations of adrenocorticotropic hormone were higher in Sprague-Dawley than in Lewis rats. In Sprague-Dawley rats, corticosterone concentrations decreased after continued handling but remained constant in Lewis rats. Interindividual variability in hormone levels was greater in Sprague-Dawley than Lewis rats, although corticosterone variability decreased after continued handling. Prolactin did not differ between groups of either Sprague-Dawley and Lewis rats before or after handling. This study underscores the importance of prolonged handling before experimenter-provided drug-administration paradigms and of strain-associated differences that may affect study outcomes.

  4. A Sample Handling System for Mars Sample Return - Design and Status

    Science.gov (United States)

    Allouis, E.; Renouf, I.; Deridder, M.; Vrancken, D.; Gelmi, R.; Re, E.

    2009-04-01

    A mission to return atmosphere and soil samples form the Mars is highly desired by planetary scientists from around the world and space agencies are starting preparation for the launch of a sample return mission in the 2020 timeframe. Such a mission would return approximately 500 grams of atmosphere, rock and soil samples to Earth by 2025. Development of a wide range of new technology will be critical to the successful implementation of such a challenging mission. Technical developments required to realise the mission include guided atmospheric entry, soft landing, sample handling robotics, biological sealing, Mars atmospheric ascent sample rendezvous & capture and Earth return. The European Space Agency has been performing system definition studies along with numerous technology development studies under the framework of the Aurora programme. Within the scope of these activities Astrium has been responsible for defining an overall sample handling architecture in collaboration with European partners (sample acquisition and sample capture, Galileo Avionica; sample containment and automated bio-sealing, Verhaert). Our work has focused on the definition and development of the robotic systems required to move the sample through the transfer chain. This paper presents the Astrium team's high level design for the surface transfer system and the orbiter transfer system. The surface transfer system is envisaged to use two robotic arms of different sizes to allow flexible operations and to enable sample transfer over relatively large distances (~2 to 3 metres): The first to deploy/retract the Drill Assembly used for sample collection, the second for the transfer of the Sample Container (the vessel containing all the collected samples) from the Drill Assembly to the Mars Ascent Vehicle (MAV). The sample transfer actuator also features a complex end-effector for handling the Sample Container. The orbiter transfer system will transfer the Sample Container from the capture

  5. CERN Sells its Electronic Document Handling System

    CERN Multimedia

    2001-01-01

    The EDH team. Left to right: Derek Mathieson, Rotislav Titov, Per Gunnar Jonsson, Ivica Dobrovicova, James Purvis. Missing from the photo is Jurgen De Jonghe. In a 1 MCHF deal announced this week, the British company Transacsys bought the rights to CERN's Electronic Document Handling (EDH) system, which has revolutionised the Laboratory's administrative procedures over the last decade. Under the deal, CERN and Transacsys will collaborate on developing EDH over the coming 12 months. CERN will provide manpower and expertise and will retain the rights to use EDH, which will also be available freely to other particle physics laboratories. This development is an excellent example of the active technology transfer policy CERN is currently pursuing. The negotiations were carried out through a fruitful collaboration between AS and ETT Divisions, following the recommendations of the Technology Advisory Board, and with the help of SPL Division. EDH was born in 1991 when John Ferguson and Achille Petrilli of AS Divisi...

  6. Primer on tritium safe handling practices

    Energy Technology Data Exchange (ETDEWEB)

    1994-12-01

    This Primer is designed for use by operations and maintenance personnel to improve their knowledge of tritium safe handling practices. It is applicable to many job classifications and can be used as a reference for classroom work or for self-study. It is presented in general terms for use throughout the DOE Complex. After reading it, one should be able to: describe methods of measuring airborne tritium concentration; list types of protective clothing effective against tritium uptake from surface and airborne contamination; name two methods of reducing the body dose after a tritium uptake; describe the most common method for determining amount of tritium uptake in the body; describe steps to take following an accidental release of airborne tritium; describe the damage to metals that results from absorption of tritium; explain how washing hands or showering in cold water helps reduce tritium uptake; and describe how tritium exchanges with normal hydrogen in water and hydrocarbons.

  7. Error handling strategies in multiphase inverse modeling

    Energy Technology Data Exchange (ETDEWEB)

    Finsterle, S.; Zhang, Y.

    2010-12-01

    Parameter estimation by inverse modeling involves the repeated evaluation of a function of residuals. These residuals represent both errors in the model and errors in the data. In practical applications of inverse modeling of multiphase flow and transport, the error structure of the final residuals often significantly deviates from the statistical assumptions that underlie standard maximum likelihood estimation using the least-squares method. Large random or systematic errors are likely to lead to convergence problems, biased parameter estimates, misleading uncertainty measures, or poor predictive capabilities of the calibrated model. The multiphase inverse modeling code iTOUGH2 supports strategies that identify and mitigate the impact of systematic or non-normal error structures. We discuss these approaches and provide an overview of the error handling features implemented in iTOUGH2.

  8. Handling of wet residues in industry

    DEFF Research Database (Denmark)

    Villanueva, Alejandro

    In countries with high prices of fresh water use and wastewater discharge, water recycling has become an alternative to traditional water consumption and discharge for industries with water-based processes. Industrial water recycling means in many cases that water has to be treated and cleaned......, to remove from it the substances which presence impedes reusing the water. These substances accumulate in a by-product called wet residue. An integral part of water recycling projects in the industry is the handling and disposal of the wet residues generated. The treatment, utilisation and disposal of wet...... residues depend totally on the industrial sector of origin and the composition of the water to be recycled. Treatment is more problematic in some cases than in others, but in all water recycling applications it is an issue of concern. The present study addresses this concern by providing a package...

  9. Handling Occlusions for Robust Augmented Reality Systems

    Directory of Open Access Journals (Sweden)

    Madjid Maidi

    2010-01-01

    Full Text Available In Augmented Reality applications, the human perception is enhanced with computer-generated graphics. These graphics must be exactly registered to real objects in the scene and this requires an effective Augmented Reality system to track the user's viewpoint. In this paper, a robust tracking algorithm based on coded fiducials is presented. Square targets are identified and pose parameters are computed using a hybrid approach based on a direct method combined with the Kalman filter. An important factor for providing a robust Augmented Reality system is the correct handling of targets occlusions by real scene elements. To overcome tracking failure due to occlusions, we extend our method using an optical flow approach to track visible points and maintain virtual graphics overlaying when targets are not identified. Our proposed real-time algorithm is tested with different camera viewpoints under various image conditions and shows to be accurate and robust.

  10. Handling Occlusions for Robust Augmented Reality Systems

    Directory of Open Access Journals (Sweden)

    Maidi Madjid

    2010-01-01

    Full Text Available Abstract In Augmented Reality applications, the human perception is enhanced with computer-generated graphics. These graphics must be exactly registered to real objects in the scene and this requires an effective Augmented Reality system to track the user's viewpoint. In this paper, a robust tracking algorithm based on coded fiducials is presented. Square targets are identified and pose parameters are computed using a hybrid approach based on a direct method combined with the Kalman filter. An important factor for providing a robust Augmented Reality system is the correct handling of targets occlusions by real scene elements. To overcome tracking failure due to occlusions, we extend our method using an optical flow approach to track visible points and maintain virtual graphics overlaying when targets are not identified. Our proposed real-time algorithm is tested with different camera viewpoints under various image conditions and shows to be accurate and robust.

  11. Handling large variations in mechanics: Some applications

    Indian Academy of Sciences (India)

    K Balaji Rao; M B Anoop; S Muralidhara; B K Raghu Prasad

    2015-08-01

    There is a need to use probability distributions with power-law decaying tails to describe the large variations exhibited by some of the physical phenomena. The Weierstrass Random Walk (WRW) shows promise for modeling such phenomena. The theory of anomalous diffusion is now well established. It has found number of applications in Physics, Chemistry and Biology. However, its applications are limited in structural mechanics in general, and structural engineering in particular. The aim of this paper is to present some mathematical preliminaries related to WRW that would help in possible applications. In the limiting case, it represents a diffusion process whose evolution is governed by a fractional partial differential equation. Three applications of superdiffusion processes in mechanics, illustrating their effectiveness in handling large variations, are presented.

  12. Development of spent fuel remote handling technology

    Energy Technology Data Exchange (ETDEWEB)

    Park, B. S.; Yoon, J. S.; Hong, H. D. (and others)

    2007-02-15

    In this research, the remote handling technology was developed for the ACP application. The ACP gives a possible solution to reduce the rapidly cumulative amount of spent fuels generated from the nuclear power plants in Korea. The remote technologies developed in this work are a slitting device, a voloxidizer, a modified telescopic servo manipulator and a digital mock-up. A slitting device was developed to declad the spent fuel rod-cuts and collect the spent fuel UO{sub 2} pellets. A voloxidizer was developed to convert the spent fuel UO{sub 2} pellets obtained from the slitting process in to U{sub 3}O{sub 8} powder. Experiments were performed to test the capabilities and remote operation of the developed slitting device and voloxidizer by using simulated rod-cuts and fuel in the ACP hot cell. A telescopic servo manipulator was redesigned and manufactured improving the structure of the prototype. This servo manipulator was installed in the ACP hot cell, and the target module for maintenance of the process equipment was selected. The optimal procedures for remote operation were made through the maintenance tests by using the servo manipulator. The ACP digital mockup in a virtual environment was established to secure a reliability and safety of remote operation and maintenance. The simulation for the remote operation and maintenance was implemented and the operability was analyzed. A digital mockup about the preliminary conceptual design of an enginnering-scale ACP was established, and an analysis about a scale of facility and remote handling was accomplished. The real-time diagnostic technique was developed to detect the possible fault accidents of the slitting device. An assessment of radiation effect for various sensors was also conducted in the radiation environment.

  13. Environmental contamination, product contamination and workers exposure using a robotic system for antineoplastic drug preparation.

    Science.gov (United States)

    Sessink, Paul J M; Leclercq, Gisèle M; Wouters, Dominique-Marie; Halbardier, Loïc; Hammad, Chaïma; Kassoul, Nassima

    2015-04-01

    Environmental contamination, product contamination and technicians exposure were measured following preparation of iv bags with cyclophosphamide using the robotic system CytoCare. Wipe samples were taken inside CytoCare, in the clean room environment, from vials, and prepared iv bags including ports and analysed for contamination with cyclophosphamide. Contamination with cyclophosphamide was also measured in environmental air and on the technicians hands and gloves used for handling the drugs. Exposure of the technicians to cyclophosphamide was measured by analysis of cyclophosphamide in urine. Contamination with cyclophosphamide was mainly observed inside CytoCare, before preparation, after preparation and after daily routine cleaning. Contamination outside CytoCare was incidentally found. All vials with reconstituted cyclophosphamide entering CytoCare were contaminated on the outside but vials with powdered cyclophosphamide were not contaminated on the outside. Contaminated bags entering CytoCare were also contaminated after preparation but non-contaminated bags were not contaminated after preparation. Cyclophosphamide was detected on the ports of all prepared bags. Almost all outer pairs of gloves used for preparation and daily routine cleaning were contaminated with cyclophosphamide. Cyclophosphamide was not found on the inner pairs of gloves and on the hands of the technicians. Cyclophosphamide was not detected in the stationary and personal air samples and in the urine samples of the technicians. CytoCare enables the preparation of cyclophosphamide with low levels of environmental contamination and product contamination and no measurable exposure of the technicians.

  14. [Risk assessment for food preparation, cooking and service].

    Science.gov (United States)

    Cottica, Danilo; Grignani, Elena

    2014-01-01

    The restaurant and food preparation, cooking and distribution sector includes hotels, restaurants, catering, fast food, ecc. The restaurant and food preparation, cooking and distribution sector form a significant part of the Italian economy; they provide employment for a large number of people, both direct employees as well as part-time and contract staff. In this sector there are many hazards that can lead to a broad range of injuries and/or diseases to the workers. For the safety these hazards principally are slick floors, open flames, high temperature cooking surfaces, steam, knives and other cutting instruments and machineries. For the health: cleaning and disinfecting chemicals substances, cooking fumes and vapors, biological agents, heavy loads handling, thermal comfort, ecc. The paper presents an overview of the hazards in the sector and then make a focus on chemical risks identification and assessment to evaluate the workers' exposure (by skin adsorption and inhalation).

  15. Instruments for minimally invasive surgery: principles of ergonomic handles.

    Science.gov (United States)

    Matern, U; Waller, P

    1999-02-01

    Although the advantages of minimally invasive surgery (MIS) have been clearly established for the patient, the surgeon must cope with disadvantages caused by unergonomic instrument handles. Pressure areas and persisting nerve lesions have been described in the literature. The shape of the instrument handles has been identified as the reason for these disorders. To prevent these, it is necessary to use ergonomically designed handles for MIS instruments. Anatomic, physiologic, and ergonomic facts as well as the results of the authors' own experiences and tests are presented. On this basis, an ideal ergonomic working posture for the laparoscopic surgeon and an optimal grasp for manipulating the instruments' functional elements are recommended. To enable the surgeon to evaluate ergonomic handles for MIS instruments according to his own needs, 14 criteria for genuine "ergonomic handles" are established. On the basis of these criteria, deficiencies of handles currently available (ring and shank handles at an angle or with axial extension to the instrument shaft, and pistol handles) are discussed. Furthermore, new handles, developed by the authors according to the criteria for genuine ergonomic handles, are presented.

  16. Simulation Augmented Manoeuvring Design and Monitoring - a New Method for Advanced Ship Handling

    Directory of Open Access Journals (Sweden)

    Knud Benedict

    2014-03-01

    Full Text Available A fast time simulation tool box is under development to simulate the ships motion with complex dynamic models and to display the ships track immediately for the intended or actual rudder or engine manoeuvre. Based on this approach the innovative Simulation Augmented Manoeuvring Design and Monitoring - SAMMON tool box will allow for (a a new type of design of a manoeuvring plan as enhancement exceeding the common pure way point planning (b an unmatched monitoring of ship handling processes to follow the underlying manoeuvring plan. During the manoeuvring process the planned manoeuvres can be constantly displayed together with the actual ship motion and the predicted future track which is based on actual input data from the ship's sensors and manoeuvring handle positions. This SAMMON tool box is intended be used on board of real ships but it is in parallel an effective tool for training in ship handling simulators: (a in the briefing for preparing a manoeuvring plan for the whole exercise in some minutes, (b during the exercise run to see the consequences of the use of manoeuvring equipment even before the ship has changed her motion and (c in debriefing sessions to discuss potential alternatives of the students decisions by simulating fast variations of their choices during the exercises. Examples will be given for results from test trials on board and in the full mission ship handling simulator of the Maritime Simulation Centre Warnemuende.

  17. Maintenance of the JET active gas handling system

    Energy Technology Data Exchange (ETDEWEB)

    Brennan, P.D. E-mail: damian.brennan@jet.uk; Bell, A.C.; Brown, K.; Cole, C.; Cooper, B.; Gibbons, C.; Harris, M.; Jones, G.; Knipe, S.; Lewis, J.; Manning, C.; Miller, A.; Perevezentsev, A.; Skinner, N.; Stagg, R.; Stead, M.; Thomas, R.; Yorkshades, J

    2003-09-01

    The JET active gas handling system (AGHS) has been in operation in conjunction with the JET machine since Spring 1997. The tritium levels within the vessel have remained sufficiently high, 6.2 g at the end of the DTE1 experiment and currently 1.5 g, such that the AGHS has been required to operate continuously to detritiate gases liberated during D-D operations and to maintain discharges to the environment to ALARP. Maintaining the system to ensure continued operation has been a key factor in guaranteeing the continued availability of the essential sub-systems. The operational history of the JET AGHS has been previously documented in a number of papers [R. Laesser, et al. Proc. of the 19th SOFT Conf. 1 (1996) 227; R. Laesser, et al., Fusion Eng. Des. 46 (1999) 307; P.D. Brennan, et al., 18th Symp. on Fusion Eng., 1999]. Operational downtime is minimised through well-engineered sub-systems that use high integrity components. Outage, contamination and operator dosage are minimised through pre-planned and prepared maintenance operations. The reliability of sub-system critical condition fault detection is demonstrated through routine testing of hard-wired alarms and interlocks.

  18. Strategy development for anticipating and handling a disruptive technology.

    Science.gov (United States)

    Chan, Stephen

    2006-10-01

    The profession of radiology has greatly benefited from the introduction of new imaging technologies throughout its history. Therefore, it would seem reasonable for radiologists to believe that the emergence of a new imaging technology can generally be foreseen with sufficient advance notice to allow the appropriate levels of time, effort, and money to be devoted toward incorporating it into radiology practice. However, in his seminal work, Christiansen characterized a new form of technologic innovation, known as "disruptive technology," whose emergence often heralds the replacement of market leaders in an industry by competitors who are quicker in adopting and deploying the new technology. This article briefly describes the phenomenon of disruptive technology and addresses the challenges that organizations face in dealing with disruptive technology. The article raises 4 questions about the future of radiology: (1) Are health care and radiology vulnerable to disruptive technology? (2) What kinds of change may be in store for the radiology profession? (3) Can the radiology profession prepare itself to recognize and respond to a disruptive innovation among a group of new imaging technologies? and (4) How should a radiology organization decide whether to invest significant resources in a potentially disruptive technology? This article addresses these questions by reviewing key insights from leading "gurus" in the fields of competitive strategy and technology management and applying them to radiology. This illustrates how and why (despite past successes) the radiology profession may still have a blind spot in recognizing and handling disruptive technologies.

  19. Encapsulated PDMS microspheres with reactive handles

    DEFF Research Database (Denmark)

    Gonzalez, Lidia; Ma, Baoguang; Li, Li

    2014-01-01

    Cured poly(dimethyl siloxane) microspheres are prepared by an emulsion polymerization reaction of silicone droplets in a continuous aqueous phase. The commonly used PDMS elastomer, Sylgard 184 from Dow Corning, is used as the dispersed phase. PDMS is polymerized and cross-linked by reacting vinyl...

  20. Improvement Of Physical Ergonomics Using Material Handling Systems

    Directory of Open Access Journals (Sweden)

    Naveen Kumar

    2015-08-01

    Full Text Available This research paper is an investigation of the physical ergonomics of the work place in an automotive parts manufacturing company . Material transfer from one station to another station was done by hand including a walk of a few steps to the next station. The unmachined components that has a quite heavy raw weight also they are being loaded and unloaded by hand .Due to this continuous practice some workers began complaining physical pain in their backs and muscular related pains. The work conditions of the workers were assessed using the REBA Rapid Entire Body Assessment test to understand the stress and the impact the work environment they are exposed to. Few material handling concepts have been suggested and explained to improve the quality of the work conditions for the workers and the REBA test tends to show some significant improvement when these improvements are implemented into the production line.

  1. Methods and apparatus for handling or treating particulate material

    Science.gov (United States)

    Littman, Howard (Inventor); Plawsky, Joel L. (Inventor); Paccione, John D. (Inventor)

    2009-01-01

    An improved draft tube spout fluid bed (DTSFB) mixing, handling, conveying, and treating apparatus and systems, and methods for operating are provided. The apparatus and systems can accept particulate material and pneumatically or hydraulically conveying the material to mix and/or treat the material. In addition to conveying apparatus, a collection and separation apparatus adapted to receive the conveyed particulate material is also provided. The collection apparatus may include an impaction plate against which the conveyed material is directed to improve mixing and/or treatment. The improved apparatus are characterized by means of controlling the operation of the pneumatic or hydraulic transfer to enhance the mixing and/or reacting by controlling the flow of fluids, for example, air, into and out of the apparatus. The disclosed apparatus may be used to mix particulate material, for example, mortar; react fluids with particulate material; coat particulate material, or simply convey particulate material.

  2. Test reports for K Basins vertical fuel handling tools

    Energy Technology Data Exchange (ETDEWEB)

    Meling, T.A.

    1995-02-01

    The vertical fuel handling tools, for moving N Reactor fuel elements, were tested in the 305 Building Cold Test Facility (CTF) in the 300 Area. After fabrication was complete, the tools were functionally tested in the CTF using simulated N Reactor fuel rods (inner and outer elements). The tools were successful in picking up the simulated N Reactor fuel rods. These tools were also load tested using a 62 pound dummy to test the structural integrity of each assembly. The tools passed each of these tests, based on the performance objectives. Finally, the tools were subjected to an operations acceptance test where K Basins Operations personnel operated the tool to determine its durability and usefulness. Operations personnel were satisfied with the tools. Identified open items included the absence of a float during testing, and documentation required prior to actual use of the tools in the 100 K fuel storage basin.

  3. Automated cassette-to-cassette substrate handling system

    Science.gov (United States)

    Kraus, Joseph Arthur; Boyer, Jeremy James; Mack, Joseph; DeChellis, Michael; Koo, Michael

    2014-03-18

    An automated cassette-to-cassette substrate handling system includes a cassette storage module for storing a plurality of substrates in cassettes before and after processing. A substrate carrier storage module stores a plurality of substrate carriers. A substrate carrier loading/unloading module loads substrates from the cassette storage module onto the plurality of substrate carriers and unloads substrates from the plurality of substrate carriers to the cassette storage module. A transport mechanism transports the plurality of substrates between the cassette storage module and the plurality of substrate carriers and transports the plurality of substrate carriers between the substrate carrier loading/unloading module and a processing chamber. A vision system recognizes recesses in the plurality of substrate carriers corresponding to empty substrate positions in the substrate carrier. A processor receives data from the vision system and instructs the transport mechanism to transport substrates to positions on the substrate carrier in response to the received data.

  4. Design and sizing of ergonomic handles for hand tools.

    Science.gov (United States)

    Lewis, W G; Narayan, C V

    1993-10-01

    In this paper, handles for two commonly used hand tools, the chisel and the off-set pliers, are designed using ergonomic principles. These were sized for both males and females falling in the 5th percentile, 50th percentile and 95th percentile groupings. The stresses developed in the ergonomically designed chisel handle while in use were analysed to verify the validity of the design. This chisel handle was then manufactured, and preliminary evaluation using electromyography was conducted. In these tests, the stresses exerted on the flexor and extensor muscles of the arm were measured and compared with those obtained during the use of a conventional handle. Under similar working conditions, results clearly showed that the ergonomically designed handle allows higher working efficiency than existing handles.

  5. Manual handling the deceased child in a children's hospice.

    Science.gov (United States)

    Pike, Anne M

    2004-09-01

    The introduction of the Manual Handling Operation Regulations 1992 has forced organizations to review all manual handling carried out in the work-place. Safe manual handling is now a legislative requirement to enable the workforce to carry out their jobs in a safe and structured environment. This project looked in detail at the manual handling that was being carried out when caring for a child after they have died. It was undertaken at CHASE Children's Hospice in the period up until December 2002, with a telephone survey investigating practice at six other children's hospices. It aimed to identify incorrect procedures and, by applying the theory of ergonomics, identify changes that needed to occur in practice, making recommendations for environmental changes. The study led to the production of a policy for handling the children, devising child-specific handling guidelines, reducing the number of times the children are moved after they have died and providing appropriate equipment.

  6. Development of software for handling ship's pharmacy.

    Science.gov (United States)

    Nittari, Giulio; Peretti, Alessandro; Sibilio, Fabio; Ioannidis, Nicholas; Amenta, Francesco

    2016-01-01

    Ships are required to carry a given amount of medicinal products and medications depending on the flag and the type of vessel. These medicines are stored in the so called ship's "medicine chest" or more properly - a ship pharmacy. Owing to the progress of medical sciences and to the increase in the mean age of seafarers employed on board ships, the number of pharmaceutical products and medical devices required by regulations to be carried on board ships is increasing. This may make handling of the ship's medicine chest a problem primarily on large ships sailing on intercontinental routes due to the difficulty in identifying the correspondence between medicines obtained abroad with those available at the national market. To minimise these problems a tool named Pharmacy Ship (acronym: PARSI) has been developed. The application PARSI is based on a database containing the information about medicines and medical devices required by different countries regulations. In the first application the system was standardised to comply with the Italian regulations issued on the 1st October, 2015 which entered into force on the 18 January 2016. Thanks to PARSI it was possible to standardize the inventory procedures, facilitate the work of maritime health authorities and make it easier for the crew, not professional in the field, to handle the 'medicine chest' correctly by automating the procedures for medicines management. As far as we know there are no other similar tools available at the moment. The application of the software, as well as the automation of different activities, currently carried out manually, will help manage (qualitatively and quantitatively) the ship's pharmacy. The system developed in this study has proved to be an effective tool which serves to guarantee the compliance of the ship pharmacy with regulations of the flag state in terms of medicinal products and medications. Sharing the system with the Telemedical Maritime Assistance Service may result in

  7. Towards an efficient retractor handle: an ergonomic study.

    Science.gov (United States)

    Brearley, S; Watson, H

    1983-11-01

    In a study whose aim was to design an ergonomically efficient retractor handle, surgeons' views on retractor design were canvassed by questionnaire. After observing retractors in use and measuring the forces involved peroperatively, prototype handles were made and tested in a laboratory. Experimental subjects showed a marked preference for a vertical 'T' configuration. Such a handle could easily be incorporated into most existing retractor designs.

  8. The prevention and handling of the missing data.

    Science.gov (United States)

    Kang, Hyun

    2013-05-01

    Even in a well-designed and controlled study, missing data occurs in almost all research. Missing data can reduce the statistical power of a study and can produce biased estimates, leading to invalid conclusions. This manuscript reviews the problems and types of missing data, along with the techniques for handling missing data. The mechanisms by which missing data occurs are illustrated, and the methods for handling the missing data are discussed. The paper concludes with recommendations for the handling of missing data.

  9. Automation of 3D micro object handling process

    DEFF Research Database (Denmark)

    Gegeckaite, Asta; Hansen, Hans Nørgaard

    2007-01-01

    Most of the micro objects in industrial production are handled with manual labour or in semiautomatic stations. Manual labour usually makes handling and assembly operations highly flexible, but slow, relatively imprecise and expensive. Handling of 3D micro objects poses special challenges due...... to the small absolute scale. In this article, the results of the pick-and-place operations of three different 3D micro objects were investigated. This study shows that depending on the correct gripping tool design as well as handling and assembly scenarios, a high success rate of up to 99% repeatability can...

  10. Human handling promotes compliant behavior in adult laboratory rabbits.

    Science.gov (United States)

    Swennes, Alton G; Alworth, Leanne C; Harvey, Stephen B; Jones, Carolyn A; King, Christopher S; Crowell-Davis, Sharon L

    2011-01-01

    Routine laboratory procedures can be stressful for laboratory animals. We wanted to determine whether human handling of adult rabbits could induce a degree of habituation, reducing stress and facilitating research-related manipulation. To this end, adult New Zealand white rabbits were handled either frequently or minimally. After being handled over 3 wk, these rabbits were evaluated by novel personnel and compared with minimally handled controls. Evaluators subjectively scored the rabbits for their relative compliance or resistance to being scruffed and removed from their cages, being transported to a treatment room, and their behavior at all stages of the exercise. Upon evaluation, handled rabbits scored significantly more compliant than nontreated controls. During evaluation, behaviors that the rabbits displayed when they were approached in their cages and while being handled outside their cages were recorded and compared between study groups. Handled rabbits displayed behavior consistent with a reduction in human-directed fear. This study illustrates the potential for handling to improve compliance in laboratory procedures and reduce fear-related behavior in laboratory rabbits. Such handling could be used to improve rabbit welfare through the reduction of stress and exposure to novel stimuli.

  11. Cooper-Harper Experience Report for Spacecraft Handling Qualities Applications

    Science.gov (United States)

    Bailey, Randall E.; Jackson, E. Bruce; Bilimoria, Karl D.; Mueller, Eric R.; Frost, Chad R.; Alderete, Thomas S.

    2009-01-01

    A synopsis of experience from the fixed-wing and rotary-wing aircraft communities in handling qualities development and the use of the Cooper-Harper pilot rating scale is presented as background for spacecraft handling qualities research, development, test, and evaluation (RDT&E). In addition, handling qualities experiences and lessons-learned from previous United States (US) spacecraft developments are reviewed. This report is intended to provide a central location for references, best practices, and lessons-learned to guide current and future spacecraft handling qualities RDT&E.

  12. MVAPACK: a complete data handling package for NMR metabolomics.

    Science.gov (United States)

    Worley, Bradley; Powers, Robert

    2014-05-16

    Data handling in the field of NMR metabolomics has historically been reliant on either in-house mathematical routines or long chains of expensive commercial software. Thus, while the relatively simple biochemical protocols of metabolomics maintain a low barrier to entry, new practitioners of metabolomics experiments are forced to either purchase expensive software packages or craft their own data handling solutions from scratch. This inevitably complicates the standardization and communication of data handling protocols in the field. We report a newly developed open-source platform for complete NMR metabolomics data handling, MVAPACK, and describe its application on an example metabolic fingerprinting data set.

  13. Pre-mortem handling effect on the meat quality

    Directory of Open Access Journals (Sweden)

    Jorgue Hernandez-Bautista

    2013-12-01

    Full Text Available The main characteristics that define meat quality are the physicochemical, organoleptic and microbiological properties. These characteristics are influenced by like production system, racial group, feed, transport, ante-mortem animals handling and post-mortem meat handling. The ante-mortem handling is very important, where stress physiology and the factors that provoke it (fasting, transportation, stunning, specie and their effect in each step of the ante-mortem handling is reflected in final meat quality (pH, conductivity, color, water holding capacity and shelf life.

  14. Compliance with safe handling guidelines of antineoplastic drugs in Jordanian hospitals.

    Science.gov (United States)

    Al-Azzam, Sayer I; Awawdeh, Banan T; Alzoubi, Karem H; Khader, Yousef S; Alkafajei, Ahmed M

    2015-02-01

    To evaluate the compliance of healthcare workers with standard safety guidelines during the preparation and administrations of antineoplastic medications. A cross-sectional survey study. All hospitals in Jordan where healthcare workers are involved in preparation and administration of antineoplastic medications. All healthcare workers who are involved in preparation and administration of antineoplastic medications in Jordanian hospitals. A questionnaire that covered information about work place, healthcare workers, and use of personal protective equipments during handling of antineoplastic medications was self-filled by each participant. Compliance rates with workplace requirements, healthcare workers, and use of personnel protective equipments. Majority of participants (74.2%), representing nine out of 15 (60%) hospitals, reported full compliance of workplace with all requirements of the guidelines. Items with full compliance in all hospitals were availability of policies and procedures for safe handling of antineoplastic agents, availability of reporting system, and availability of sharp containers. Concerning healthcare workers' guidelines, worker with full compliance were 46.4% of participants. Items with least compliance rate were working inside biological safety cabinet (65.1%) and having training program on handling chemotherapy medications (66.7%). Finally, concerning items-related personal protective equipments, only 10.7% of participants reported full compliance. Items with least compliance rates were wearing goggles (eye protection), shoe cover, and hair cover. Results of this study showed the levels of compliance with guidelines pertaining to work place and workers who prepare and administer antineoplastic medications. Among other points, compliance with guidelines pertaining to wearing personnel protective equipments was limited and required further improvement. © The Author(s) 2014 Reprints and permissions: sagepub.co.uk/journalsPermissions.nav.

  15. Mars Sample Handling and Requirements Panel (MSHARP)

    Science.gov (United States)

    Carr, Michael H.; McCleese, Daniel J.; Bada, Jeffrey L.; Bogard, Donald D.; Clark, Benton C.; DeVincenzi, Donald; Drake, Michael J.; Nealson, Kenneth H.; Papike, James J.; Race, Margaret S.; Stahl, David

    1999-01-01

    In anticipation of the return of samples from Mars toward the end of the first decade of the next century, NASA's Office of Space Sciences chartered a panel to examine how Mars samples should be handled. The panel was to make recommendations in three areas: (1) sample collection and transport back to Earth; (2) certification of the samples as nonhazardous; and (3) sample receiving, curation, and distribution. This report summarizes the findings of that panel. The samples should be treated as hazardous until proven otherwise. They are to be sealed within a canister on Mars, and the canister is not to be opened until within a Biosafety Hazard Level 4 (BSL-4) containment facility here on Earth. This facility must also meet or exceed the cleanliness requirements of the Johnson Space Center (JSC) facility for curation of extraterrestrial materials. A containment facility meeting both these requirements does not yet exist. Hazard assessment and life detection experiments are to be done at the containment facility, while geochemical characterization is being performed on a sterilized subset of the samples released to the science community. When and if the samples are proven harmless, they are to be transferred to a curation facility, such as that at JSC.

  16. Valve Concepts for Microfluidic Cell Handling

    Directory of Open Access Journals (Sweden)

    M. Grabowski

    2010-01-01

    Full Text Available In this paper we present various pneumatically actuated microfluidic valves to enable user-defined fluid management within a microfluidic chip. To identify a feasible valve design, certain valve concepts are simulated in ANSYS to investigate the pressure dependent opening and closing characteristics of each design. The results are verified in a series of tests. Both the microfluidic layer and the pneumatic layer are realized by means of soft-lithographic techniques. In this way, a network of channels is fabricated in photoresist as a molding master. By casting these masters with PDMS (polydimethylsiloxane we get polymeric replicas containing the channel network. After a plasma-enhanced bonding process, the two layers are irreversibly bonded to each other. The bonding is tight for pressures up to 2 bar. The valves are integrated into a microfluidic cell handling system that is designed to manipulate cells in the presence of a liquid reagent (e.g. PEG – polyethylene glycol, for cell fusion. For this purpose a user-defined fluid management system is developed. The first test series with human cell lines show that the microfluidic chip is suitable for accumulating cells within a reaction chamber, where they can be flushed by a liquid medium.

  17. Whole Teflon valves for handling droplets.

    Science.gov (United States)

    Cybulski, Olgierd; Jakiela, Slawomir; Garstecki, Piotr

    2016-06-21

    We propose and test a new whole-Teflon gate valve for handling droplets. The valve allows droplet plugs to pass through without disturbing them. This is possible due to the geometric design, the choice of material and lack of any pulses of flow generated by closing or opening the valve. The duct through the valve resembles a simple segment of tubing, without constrictions, change in lumen or side pockets. There are no extra sealing materials with different wettability or chemical resistance. The only material exposed to liquids is FEP Teflon, which is resistant to aggressive chemicals and fully biocompatible. The valve can be integrated into microfluidic systems: we demonstrate a complex system for culturing bacteria in hundreds of microliter droplet chemostats. The valve effectively isolates modules of the system to increase precision of operations on droplets. We verified that the valve allowed millions of droplet plugs to safely pass through, without any cross-contamination with bacteria between the droplets. The valve can be used in automating complex microfluidic systems for experiments in biochemistry, biology and organic chemistry.

  18. The NOAO KOSMOS Data Handling System

    CERN Document Server

    Seaman, Rob

    2015-01-01

    KOSMOS and COSMOS are twin high-efficiency imaging spectrographs that have been deployed as NOAO facility instruments for the Mayall 4-meter telescope on Kitt Peak in Arizona and for the Blanco telescope on Cerro Tololo in Chile, respectively. The NOAO Data Handling System (DHS) has seen aggressive use over several years at both the Blanco and Mayall telescopes with NEWFIRM (the NOAO Extremely Wide-Field Infrared Imager) and the Mosaic-1.1 wide-field optical imager. Both of these instruments also rely on the Monsoon array controller and related software, and on instrument-specific versions of the NOAO Observation Control System (NOCS). NOCS, Monsoon and DHS are thus a well-tested software suite that was adopted by the KOSMOS project. This document describes the specifics of the KOSMOS implementation of DHS, in particular in support of the original two-amplifier e2v 2Kx4K CCD detectors with which the instruments were commissioned. The emphasis will be on the general layout of the DHS software components and th...

  19. Cocaine-induced locomotor activity is increased by prior handling in adolescent but not adult female rats

    Science.gov (United States)

    Maldonado, Antoniette M.; Kirstein, Cheryl L.

    2017-01-01

    Adolescence is a period of transition that is associated with increased levels of stress and a heightened propensity to initiate drug use. Neuronal development is still occurring during this transitional period, which includes the continued development of the dopamine system during the adolescent period. In the present study, the effects of pre-test handling on cocaine-induced locomotor activity were investigated among female adolescent and young adult rats upon presentation to a novel environment. On postnatal days (PND) 41–44 and 56–59 animals were handled (b.i.d.) in the colony room for 3 min. On PND 45 or PND 60, animals were removed from the colony room, weighed, and administered an acute injection of either cocaine or saline and presented to a novel environment where behavior was recorded for 30 min. Adolescent females (PND 45) that were handled prior to cocaine administration demonstrated elevated levels of cocaine-induced activity relative to their age-matched non-handled counterparts and also to their handled-adult counterparts. In contrast, among non-handled animals, young adults (PND 60) exhibited elevated drug-induced locomotion at several time points during the trial. Non-handled adolescent animals demonstrated the previously described “hyporesponsive” behavioral profile relative to their non-handled adult counterparts. The results from the present experiment indicate that adolescent animals may be more sensitive to basic laboratory manipulations such as pre-test handling, and care must be taken when utilizing adolescent animals in behavioral testing. Handling appears to be a sensitive manipulation in elucidating differences in cocaine-induced behavioral activation between ages. PMID:16176824

  20. Comparison of the Rapid Entire Body Assessment and the New Zealand Manual Handling 'Hazard Control Record', for assessment of manual handling hazards in the supermarket industry.

    Science.gov (United States)

    Coyle, Alison

    2005-01-01

    This is a case study comparing the use of two different assessment tools (Rapid Entire Body Assessment versus New Zealand Manual Handling Hazard Control Record) to assess, plan and implement changes in manual handling practices in the supermarket industry. Existing manual handling practices being used within these supermarkets were assessed using each of these tools. The most hazardous tasks were revised to improve work methods and reviewed again using both tools, to determine the usefulness and effectiveness of these tools. The process generated considerable discussion regarding the benefits and drawbacks of each tool. The usefulness of each tool appears dependant on the reason for assessment and the anticipated outcome. REBA may be more useful if specific ergonomic or biomechanical changes are being implemented to decrease risk of work-related injury (particularly if an objective numeric score is required for re-assessment following modifications, to determine their effectiveness). The New Zealand Code of Practice for Manual Handling 'Hazard Control Record' Risk Score analysis process lacks specificity and objectivity, however it is less reductionistic and takes into account many factors other than biomechanics and ergonomics. It directs the user toward implementing controls, which are thorough, multi-factorial and useful to control hazards relating to several other areas, including task, load, environment, people and management factors.

  1. THE COMPARATIVE STUDY OF STANDARD MACINTOSH HANDLE VERSUS SHORT HANDLE FOR LARYNGOSCOPY AND INTUBATION IN OBSTETRIC PATIENTS FOR LOWER SEGMENT CESAREAN SECTION

    Directory of Open Access Journals (Sweden)

    Neeharika

    2014-09-01

    Full Text Available : INTRODUCTION: The incidence of failed intubation is higher in obstetrics (1:280 than other surgical patients (1:2230. The anatomical factors that place the pregnant patient at increased risk for airway complications and difficult intubation include pregnancy induced generalized weight gain particularly increase in breast size, respiratory mucosal edema, and an increased risk of pulmonary aspiration. In the supine position, the enlarged breasts tend to fall back against the neck, which can interfere with insertion of the laryngoscope. The aim of our study is to assess the efficacy of short handle laryngoscope versus standard Macintosh handle laryngoscope for laryngoscopy and intubation in obstetric patients posted for Lower Segment Cesarean Section. PLAN OF STUDY: Randomized prospective study. ASA grade I and II full term obstetric patients posted for elective or emergency LSCS studied in two groups[ Group I (n=20 - Standard Macintosh handle, Group II (n=20 - Short / stubby handle (Anesthetics make, India]. Height and weight of patients were recorded. Head, neck and oral cavity of the patient were examined to rule out any obvious pathology and to detect any anticipated difficult intubations for exclusion. Examination of the airway included: neck length, sternomental distance, thyromental distance, inter incisor gap, chest circumference and modified Mallampati grading. The observations noted during laryngoscopy: number of attempts for insertion of laryngoscope into oral cavity, ease of insertion of laryngoscope blade into oral cavity, number of attempts for successful intubation, duration of laryngoscopy and intubation, perpendicular distance from the lower edge of distal end of laryngoscope handle to patient’s chest wall. OBSERVATIONS: The perpendicular distance was significantly higher in group II (16 cm than group I (13.6 cm.The time for laryngoscopy and intubation hard a significant correlation to weight as well as chest circumference in

  2. Handling stress does not reflect personality in female zebra finches (Taeniopygia guttata).

    Science.gov (United States)

    David, Morgan; Auclair, Yannick; Dechaume-Moncharmont, François-Xavier; Cézilly, Frank

    2012-02-01

    Although increasing attention is given to both the causes and consequences of variation in animal personality, the measurement of personality in captive or free-ranging individuals remains an issue. In particular, one important question concerns whether personality should be established from the existence of complex behavioral syndromes (a suite of correlated behavioral traits) or could be more easily deduced from a single variable. In that context, it has recently been suggested that handling stress, measured through breathing rate during handling, could be a good descriptor of personality, at least in passerine birds. The authors experimentally investigated to what extent handling stress was correlated with personality in female zebra finches (Taeniopygia guttata), as assessed from a suite of repeatable behavioral traits, including activity, exploratory behavior, neophobia, and reaction to startle. Although breathing rate was repeatable across individuals, it was not related to any behavioral trait, suggesting that it cannot be used to quickly predict personality, at least in zebra finches. Breathing rate during handling, in addition, was related to morphology, questioning the fact that breathing rate during handling reflects personality irrespective of individual state. The authors suggest that inference on global personality from a reduced number of traits should be performed with caution.

  3. Quantification of Patient and Equipment Handling for Nurses through Direct Observation and Subjective Perceptions

    Directory of Open Access Journals (Sweden)

    Tiffany Poole Wilson

    2015-01-01

    Full Text Available Background. Musculoskeletal disorders have continued to plague nurses in hospitals and long-term care facilities. Low back and shoulder injuries are the most prevalent, frequently linked to patient handling activities. Exposure to patient handling has been predominantly quantified by subjective responses of nurses. Objective. To directly observe handling of patients and other medical equipment for nurses during a 12-hour work shift. Methods. Twenty nurses working in three different intensive care units at a Midwest teaching hospital were directly observed during 12-hour day shifts. Direct observation included documenting frequency and type of handling performed and whether lift assist devices were utilized. Two additional surveys were completed by nurses to assess current pain levels and perceptions of lifting being performed. The observed lifting was compared to the perceived lifting with simple inference statistics. Results. Nurses have a high prevalence of manually lifting patients and medical devices but limited use of lifting assist devices. Nurses handled patients 69 times per shift and medical equipment 6 times per shift, but less than 3% utilized a lift assist device. Nurses suffered from high levels of pain at the end of the shift, with the highest prevalence in the lower back, lower legs, and feet/ankles (all above 60%.

  4. Ground Handling of Batteries at Test and Launch-site Facilities

    Science.gov (United States)

    Jeevarajan, Judith A.; Hohl, Alan R.

    2008-01-01

    Ground handling of flight as well as engineering batteries at test facilities and launch-site facilities is a safety critical process. Test equipment interfacing with the batteries should have the required controls to prevent a hazardous failure of the batteries. Test equipment failures should not induce catastrophic failures on the batteries. Transportation requirements for batteries should also be taken into consideration for safe transportation. This viewgraph presentation includes information on the safe handling of batteries for ground processing at test facilities as well as launch-site facilities.

  5. Handling stress may confound murine gut microbiota studies

    Directory of Open Access Journals (Sweden)

    Cary R. Allen-Blevins

    2017-01-01

    Full Text Available Background Accumulating evidence indicates interactions between human milk composition, particularly sugars (human milk oligosaccharides or HMO, the gut microbiota of human infants, and behavioral effects. Some HMO secreted in human milk are unable to be endogenously digested by the human infant but are able to be metabolized by certain species of gut microbiota, including Bifidobacterium longum subsp. infantis (B. infantis, a species sensitive to host stress (Bailey & Coe, 2004. Exposure to gut bacteria like B. infantisduring critical neurodevelopment windows in early life appears to have behavioral consequences; however, environmental, physical, and social stress during this period can also have behavioral and microbial consequences. While rodent models are a useful method for determining causal relationships between HMO, gut microbiota, and behavior, murine studies of gut microbiota usually employ oral gavage, a technique stressful to the mouse. Our aim was to develop a less-invasive technique for HMO administration to remove the potential confound of gavage stress. Under the hypothesis that stress affects gut microbiota, particularly B. infantis, we predicted the pups receiving a prebiotic solution in a less-invasive manner would have the highest amount of Bifidobacteria in their gut. Methods This study was designed to test two methods, active and passive, of solution administration to mice and the effects on their gut microbiome. Neonatal C57BL/6J mice housed in a specific-pathogen free facility received increasing doses of fructooligosaccharide (FOS solution or deionized, distilled water. Gastrointestinal (GI tracts were collected from five dams, six sires, and 41 pups over four time points. Seven fecal pellets from unhandled pups and two pellets from unhandled dams were also collected. Qualitative real-time polymerase chain reaction (qRT-PCR was used to quantify and compare the amount of Bifidobacterium, Bacteroides, Bacteroidetes, and

  6. Orion Handling Qualities During ISS Rendezvous and Docking

    Science.gov (United States)

    Hart, Jeremy J.; Stephens, J. P.; Spehar, P.; Bilimoria, K.; Foster, C.; Gonzalex, R.; Sullivan, K.; Jackson, B.; Brazzel, J.; Hart, J.

    2011-01-01

    The Orion spacecraft was designed to rendezvous with multiple vehicles in low earth orbit (LEO) and beyond. To perform the required rendezvous and docking task, Orion must provide enough control authority to perform coarse translational maneuvers while maintaining precision to perform the delicate docking corrections. While Orion has autonomous docking capabilities, it is expected that final approach and docking operations with the International Space Station (ISS) will initially be performed in a manual mode. A series of evaluations was conducted by NASA and Lockheed Martin at the Johnson Space Center to determine the handling qualities (HQ) of the Orion spacecraft during different docking and rendezvous conditions using the Cooper-Harper scale. This paper will address the specifics of the handling qualities methodology, vehicle configuration, scenarios flown, data collection tools, and subject ratings and comments. The initial Orion HQ assessment examined Orion docking to the ISS. This scenario demonstrates the Translational Hand Controller (THC) handling qualities of Orion. During this initial assessment, two different scenarios were evaluated. The first was a nominal docking approach to a stable ISS, with Orion initializing with relative position dispersions and a closing rate of approximately 0.1 ft/sec. The second docking scenario was identical to the first, except the attitude motion of the ISS was modeled to simulate a stress case ( 1 degree deadband per axis and 0.01 deg/sec rate deadband per axis). For both scenarios, subjects started each run on final approach at a docking port-to-port range of 20 ft. Subjects used the THC in pulse mode with cues from the docking camera image, window views, and range and range rate data displayed on the Orion display units. As in the actual design, the attitude of the Orion vehicle was held by the automated flight control system at 0.5 degree deadband per axis. Several error sources were modeled including Reaction

  7. Handling stress may confound murine gut microbiota studies

    Science.gov (United States)

    Allen-Blevins, Cary R.; You, Xiaomeng; Hinde, Katie

    2017-01-01

    Background Accumulating evidence indicates interactions between human milk composition, particularly sugars (human milk oligosaccharides or HMO), the gut microbiota of human infants, and behavioral effects. Some HMO secreted in human milk are unable to be endogenously digested by the human infant but are able to be metabolized by certain species of gut microbiota, including Bifidobacterium longum subsp. infantis (B. infantis), a species sensitive to host stress (Bailey & Coe, 2004). Exposure to gut bacteria like B. infantisduring critical neurodevelopment windows in early life appears to have behavioral consequences; however, environmental, physical, and social stress during this period can also have behavioral and microbial consequences. While rodent models are a useful method for determining causal relationships between HMO, gut microbiota, and behavior, murine studies of gut microbiota usually employ oral gavage, a technique stressful to the mouse. Our aim was to develop a less-invasive technique for HMO administration to remove the potential confound of gavage stress. Under the hypothesis that stress affects gut microbiota, particularly B. infantis, we predicted the pups receiving a prebiotic solution in a less-invasive manner would have the highest amount of Bifidobacteria in their gut. Methods This study was designed to test two methods, active and passive, of solution administration to mice and the effects on their gut microbiome. Neonatal C57BL/6J mice housed in a specific-pathogen free facility received increasing doses of fructooligosaccharide (FOS) solution or deionized, distilled water. Gastrointestinal (GI) tracts were collected from five dams, six sires, and 41 pups over four time points. Seven fecal pellets from unhandled pups and two pellets from unhandled dams were also collected. Qualitative real-time polymerase chain reaction (qRT-PCR) was used to quantify and compare the amount of Bifidobacterium, Bacteroides, Bacteroidetes, and Firmicutes

  8. Handling stress may confound murine gut microbiota studies.

    Science.gov (United States)

    Allen-Blevins, Cary R; You, Xiaomeng; Hinde, Katie; Sela, David A

    2017-01-01

    Accumulating evidence indicates interactions between human milk composition, particularly sugars (human milk oligosaccharides or HMO), the gut microbiota of human infants, and behavioral effects. Some HMO secreted in human milk are unable to be endogenously digested by the human infant but are able to be metabolized by certain species of gut microbiota, including Bifidobacterium longum subsp. infantis (B. infantis), a species sensitive to host stress (Bailey & Coe, 2004). Exposure to gut bacteria like B. infantisduring critical neurodevelopment windows in early life appears to have behavioral consequences; however, environmental, physical, and social stress during this period can also have behavioral and microbial consequences. While rodent models are a useful method for determining causal relationships between HMO, gut microbiota, and behavior, murine studies of gut microbiota usually employ oral gavage, a technique stressful to the mouse. Our aim was to develop a less-invasive technique for HMO administration to remove the potential confound of gavage stress. Under the hypothesis that stress affects gut microbiota, particularly B. infantis, we predicted the pups receiving a prebiotic solution in a less-invasive manner would have the highest amount of Bifidobacteria in their gut. This study was designed to test two methods, active and passive, of solution administration to mice and the effects on their gut microbiome. Neonatal C57BL/6J mice housed in a specific-pathogen free facility received increasing doses of fructooligosaccharide (FOS) solution or deionized, distilled water. Gastrointestinal (GI) tracts were collected from five dams, six sires, and 41 pups over four time points. Seven fecal pellets from unhandled pups and two pellets from unhandled dams were also collected. Qualitative real-time polymerase chain reaction (qRT-PCR) was used to quantify and compare the amount of Bifidobacterium, Bacteroides, Bacteroidetes, and Firmicutes. Our results demonstrate

  9. 3.1.1.2 Feed Processing and Handling DL2 Final Report

    Energy Technology Data Exchange (ETDEWEB)

    Elliott, Douglas C.; Magnuson, Jon K.; Wend, Christopher F.

    2006-09-30

    This milestone report is the deliverable for our Feed Processing and Handling project. It includes results of wet biomass feedstock analysis, slurry pumping information, fungal processing to produce a lignin-rich biorefinery residue and two subcontracted efforts to quantify the amount of wet biomass feedstocks currently available within the corn processing and paper processing industries.

  10. Early Childhood Inservice and Preservice Teachers' Perceived Levels of Preparedness to Handle Stress in Their Students

    Science.gov (United States)

    Onchwari, Jacqueline

    2010-01-01

    This article reports a study that investigated preservice and inservice early childhood teachers' perceived levels of preparedness to handle stress in early childhood and elementary education students. A survey that included vignettes was used to collect data. Data were analyzed both qualitatively and statistically, using one-way ANOVA, "t"-test,…

  11. A simulation-based approach for evaluating logging residue handling systems.

    Science.gov (United States)

    B. Bruce Bare; Benjamin A. Jayne; Brian F. Anholt

    1976-01-01

    Describes a computer simulation model for evaluating logging residue handling systems. The flow of resources is traced through a prespecified combination of operations including yarding, chipping, sorting, loading, transporting, and unloading. The model was used to evaluate the feasibility of converting logging residues to chips that could be used, for example, to...

  12. Electrophysiological properties and calcium handling of embryonic stem cell-derived cardiomyocytes

    Directory of Open Access Journals (Sweden)

    Jae Boum Youm

    2016-03-01

    Full Text Available Embryonic stem cell-derived cardiomyocytes (ESC-CMs hold great interest in many fields of research including clinical applications such as stem cell and gene therapy for cardiac repair or regeneration. ESC-CMs are also used as a platform tool for pharmacological tests or for investigations of cardiac remodeling. ESC-CMs have many different aspects of morphology, electrophysiology, calcium handling, and bioenergetics compared with adult cardiomyocytes. They are immature in morphology, similar to sinus nodal-like in the electrophysiology, higher contribution of trans-sarcolemmal Ca2+ influx to Ca2+ handling, and higher dependence on anaerobic glycolysis. Here, I review a detailed electrophysiology and Ca2+ handling features of ESC-CMs during differentiation into adult cardiomyocytes to gain insights into how all the developmental changes are related to each other to display cardinal features of developing cardiomyocytes.

  13. [Ergonomic analysis of the handle of manual instruments for dental hygiene].

    Science.gov (United States)

    Migliario, Mario; Franchignoni, Marco; Soldati, Libero; Melle, Andrea; Carcieri, Paola; Ferriero, Giorgio

    2012-01-01

    Work-related musculoskeletal disorders of upper limbs are very common among dental hygienists. To minimize the risk of their occurrence, it is essential that attention be paid to proper ergonomics in the workplace, including the selection of instrumentation. At present there are no specific guidelines but only some indications for the selection of the different hand tools. The main purpose of this study was to make a comparative analysis of different types of handles of hand tools used for root planing (Gracey curettes). Nine dental hygienists were interviewed with a questionnaire aimed to assess three different types of curette handle. The results showed that lightness, being of solid steel, having a cylindrical non-uniform shape with full enlarged cross-section, and being silicon coated with non-slip ends are the preferred characteristics for a curette handle. These considerations may assist both manufacturers in designing new hand instruments and clinicians in selecting the most ergonomic ones to buy.

  14. Confusional State in HaNDL Syndrome: Case Report and Literature Review

    Directory of Open Access Journals (Sweden)

    Sarah Nelson

    2013-01-01

    Full Text Available The syndrome of transient headache and neurologic deficits with cerebrospinal fluid lymphocytosis (HaNDL syndrome is a self-limited condition. Confusional states are uncommonly reported as a clinical manifestation of this syndrome. Here, I report a 76-year-old female who presented with headache, confusion, and agitation with a mild CSF lymphocytosis. Other workup to determine the cause of her altered mental status was otherwise negative. The literature available in the English language on HaNDL syndrome is reviewed, including its history, pathophysiology, possible associations with migraine and stroke, and previously reported cases of confusional states in this syndrome. While HaNDL syndrome has been a described entity since the 1980s, its pathophysiology has yet to be clearly defined.

  15. Advanced robotics handling and controls applied to Mixed Waste characterization, segregation and treatment

    Energy Technology Data Exchange (ETDEWEB)

    Grasz, E.; Huber, L.; Horvath, J.; Roberson, P.; Wilhelmsen, K.; Ryon, R.

    1994-11-01

    At Lawrence Livermore National Laboratory under the Mixed Waste Operations program of the Department of Energy Robotic Technology Development Program (RTDP), a key emphasis is developing a total solution to the problem of characterizing, handling and treating complex and potentially unknown mixed waste objects. LLNL has been successful at looking at the problem from a system perspective and addressing some of the key issues including non-destructive evaluation of the waste stream prior to the materials entering the handling workcell, the level of automated material handling required for effective processing of the waste stream objects (both autonomous and tele-operational), and the required intelligent robotic control to carry out the characterization, segregation, and waste treating processes. These technologies were integrated and demonstrated in a prototypical surface decontamination workcell this past year.

  16. Robust telerobotics - an integrated system for waste handling, characterization and sorting

    Energy Technology Data Exchange (ETDEWEB)

    Couture, S.A.; Hurd, R.L.; Wilhelmsen, K.C.

    1997-01-01

    The Mixed Waste Management Facility (MWMF) at the Lawrence Livermore National Laboratory was designed to serve as a national testbed to demonstrate integrated technologies for the treatment of low-level organic mixed waste at a pilot-plant scale. Pilot-scale demonstration serves to bridge the gap between mature, bench-scale proven technologies and full-scale treatment facilities by providing the infrastructure needed to evaluate technologies in an integrated, front-end to back-end facility. Consistent with the intent to focus on technologies that are ready for pilot scale deployment, the front-end handling and feed preparation of incoming waste material has been designed to demonstrate the application of emerging robotic and remotely operated handling systems. The selection of telerobotics for remote handling in MWMF was made based on a number of factors - personnel protection, waste generation, maturity, cost, flexibility and extendibility. Telerobotics, or shared control of a manipulator by an operator and a computer, provides the flexibility needed to vary the amount of automation or operator intervention according to task complexity. As part of the telerobotics design effort, the technical risk of deploying the technology was reduced through focused developments and demonstrations. The work involved integrating key tools (1) to make a robust telerobotic system that operates at speeds and reliability levels acceptable to waste handling operators and, (2) to demonstrate an efficient operator interface that minimizes the amount of special training and skills needed by the operator. This paper describes the design and operation of the prototype telerobotic waste handling and sorting system that was developed for MWMF.

  17. Handling of damaged spent fuel at Ignalina NPP

    Energy Technology Data Exchange (ETDEWEB)

    Ziehm, Ronny [NUKEM Technologies GmbH (Germany); Bechtel, Sascha [Hoefer und Bechtel GmbH (Germany)

    2012-11-01

    The Ignalina Nuclear Power Plant (INPP) is situated in the north-eastern part of Lithuania close to the borders with Latvia and Belarus and on the shore of Lake Druksiai. It is approximately 120 km from the capital city Vilnius. The power plant has two RMBK type water cooled graphite moderated pressure tube reactors each of design capacity 1500MW(e). The start of operation of the Unit 1 was in 1983 and of the Unit 2 in 1987. In the period 1987 - 1991 (i.e. Soviet period) a small proportion of the existing spent nuclear fuel suffered minor to major damages. In the frame of decommissioning of INPP it is necessary that this damaged fuel is retrieved from the storage pools and stored in an interim spent fuel store. NUKEM Technologies GmbH (Germany) as part of a consortium with GNS mbH (Germany) was awarded the contract for an Interim Spent Fuel Storage Facility (B1- ISFSF). This contract includes the design, procurement, manufacturing, supply and installation of a damaged fuel handling system (DFHS). Objective of this DFHS is the safe handling of spent nuclear fuel with major damages, which result in rupture of the cladding and potential loss of fuel pellets from within the cladding. Typical damages are bent fuel bundle skeletons, broken fuel rods, missing or damaged end plugs, very small gaps between fuel bundles, bent central rods between fuel bundles. The presented concept is designed for Ignalina NPP. However, the design is developed more generally to solve these problems with damaged fuel at other nuclear power plants applying these proven techniques. (orig.)

  18. An Empirical Analysis of Stakeholders' Influence on Policy Development: the Role of Uncertainty Handling

    Directory of Open Access Journals (Sweden)

    Rianne M. Bijlsma

    2011-03-01

    Full Text Available Stakeholder participation is advocated widely, but there is little structured, empirical research into its influence on policy development. We aim to further the insight into the characteristics of participatory policy development by comparing it to expert-based policy development for the same case. We describe the process of problem framing and analysis, as well as the knowledge base used. We apply an uncertainty perspective to reveal differences between the approaches and speculate about possible explanations. We view policy development as a continuous handling of substantive uncertainty and process uncertainty, and investigate how the methods of handling uncertainty of actors influence the policy development. Our findings suggest that the wider frame that was adopted in the participatory approach was the result of a more active handling of process uncertainty. The stakeholders handled institutional uncertainty by broadening the problem frame, and they handled strategic uncertainty by negotiating commitment and by including all important stakeholder criteria in the frame. In the expert-based approach, we observed a more passive handling of uncertainty, apparently to avoid complexity. The experts handled institutional uncertainty by reducing the scope and by anticipating windows of opportunity in other policy arenas. Strategic uncertainty was handled by assuming stakeholders' acceptance of noncontroversial measures that balanced benefits and sacrifices. Three other observations are of interest to the scientific debate on participatory policy processes. Firstly, the participatory policy was less adaptive than the expert-based policy. The observed low tolerance for process uncertainty of participants made them opt for a rigorous "once and for all" settling of the conflict. Secondly, in the participatory approach, actors preferred procedures of traceable knowledge acquisition over controversial topics to handle substantive uncertainty. This

  19. Mission Need Statement for the Idaho National Laboratory Remote-Handled Low-Level Waste Disposal Project

    Energy Technology Data Exchange (ETDEWEB)

    Lisa Harvego

    2009-06-01

    The Idaho National Laboratory proposes to establish replacement remote-handled low-level waste disposal capability to meet Nuclear Energy and Naval Reactors mission-critical, remote-handled low-level waste disposal needs beyond planned cessation of existing disposal capability at the end of Fiscal Year 2015. Remote-handled low-level waste is generated from nuclear programs conducted at the Idaho National Laboratory, including spent nuclear fuel handling and operations at the Naval Reactors Facility and operations at the Advanced Test Reactor. Remote-handled low-level waste also will be generated by new programs and from segregation and treatment (as necessary) of remote-handled scrap and waste currently stored in the Radioactive Scrap and Waste Facility at the Materials and Fuels Complex. Replacement disposal capability must be in place by Fiscal Year 2016 to support uninterrupted Idaho operations. This mission need statement provides the basis for the laboratory’s recommendation to the Department of Energy to proceed with establishing the replacement remote-handled low-level waste disposal capability, project assumptions and constraints, and preliminary cost and schedule information for developing the proposed capability. Without continued remote-handled low-level waste disposal capability, Department of Energy missions at the Idaho National Laboratory would be jeopardized, including operations at the Naval Reactors Facility that are critical to effective execution of the Naval Nuclear Propulsion Program and national security. Remote-handled low-level waste disposal capability is also critical to the Department of Energy’s ability to meet obligations with the State of Idaho.

  20. Optimal event handling by multiple unmanned aerial vehicles

    NARCIS (Netherlands)

    Roo, de Martijn; Frasca, Paolo; Carloni, Raffaella

    2016-01-01

    This paper proposes a control architecture for a fleet of unmanned aerial vehicles that is responsible for handling the events that take place in a given area. The architecture guarantees that each event is handled by the required number of vehicles in the shortest time, while the rest of the fleet

  1. 45 CFR 650.19 - Electronic invention handling.

    Science.gov (United States)

    2010-10-01

    ... 45 Public Welfare 3 2010-10-01 2010-10-01 false Electronic invention handling. 650.19 Section 650... PATENTS § 650.19 Electronic invention handling. (a) Grantees must use the iEdison Invention Information Management System maintained by the National Institutes of Health to disclose NSF subject inventions...

  2. Incorporating Handling Qualities Analysis into Rotorcraft Conceptual Design

    Science.gov (United States)

    Lawrence, Ben

    2014-01-01

    This paper describes the initial development of a framework to incorporate handling qualities analyses into a rotorcraft conceptual design process. In particular, the paper describes how rotorcraft conceptual design level data can be used to generate flight dynamics models for handling qualities analyses. Also, methods are described that couple a basic stability augmentation system to the rotorcraft flight dynamics model to extend analysis to beyond that of the bare airframe. A methodology for calculating the handling qualities characteristics of the flight dynamics models and for comparing the results to ADS-33E criteria is described. Preliminary results from the application of the handling qualities analysis for variations in key rotorcraft design parameters of main rotor radius, blade chord, hub stiffness and flap moment of inertia are shown. Varying relationships, with counteracting trends for different handling qualities criteria and different flight speeds are exhibited, with the action of the control system playing a complex part in the outcomes. Overall, the paper demonstrates how a broad array of technical issues across flight dynamics stability and control, simulation and modeling, control law design and handling qualities testing and evaluation had to be confronted to implement even a moderately comprehensive handling qualities analysis of relatively low fidelity models. A key outstanding issue is to how to 'close the loop' with an overall design process, and options for the exploration of how to feedback handling qualities results to a conceptual design process are proposed for future work.

  3. Priming of Reach and Grasp Actions by Handled Objects

    Science.gov (United States)

    Masson, Michael E. J.; Bub, Daniel N.; Breuer, Andreas T.

    2011-01-01

    Pictures of handled objects such as a beer mug or frying pan are shown to prime speeded reach and grasp actions that are compatible with the object. To determine whether the evocation of motor affordances implied by this result is driven merely by the physical orientation of the object's handle as opposed to higher-level properties of the object,…

  4. How do new product development startups handle missing expertise?

    NARCIS (Netherlands)

    Eris, O.; van den Eijnden, W.; Roling, M.

    2014-01-01

    This paper presents a framework for how new product development focused startup firms (NPDSF) handle missing expertise. The dimensions of the framework are: strategies for handling missing expertise, channels used to acquire missing expertise, and a priori awareness, timing and nature of missing exp

  5. New Ergonomic Design Criteria for Handles of Laparoscopic Dissection Forceps

    NARCIS (Netherlands)

    Van Veelen, M.A.; Meijer, D.W.; Goossens, R.H.M.; Snijders, C.J.

    2001-01-01

    Background: The shape of laparoscopic instrument handles can cause physical discomfort. This problem may be ascribed to a lack of standards for instrument design. In this study, new ergonomic requirements for the design of laparoscopic dissection forceps were created. Three representative handles (a

  6. A Review of Missing Data Handling Methods in Education Research

    Science.gov (United States)

    Cheema, Jehanzeb R.

    2014-01-01

    Missing data are a common occurrence in survey-based research studies in education, and the way missing values are handled can significantly affect the results of analyses based on such data. Despite known problems with performance of some missing data handling methods, such as mean imputation, many researchers in education continue to use those…

  7. 9 CFR 2.131 - Handling of animals.

    Science.gov (United States)

    2010-01-01

    ... 9 Animals and Animal Products 1 2010-01-01 2010-01-01 false Handling of animals. 2.131 Section 2.131 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE ANIMAL WELFARE REGULATIONS Miscellaneous § 2.131 Handling of animals. (a) All licensees who maintain...

  8. 21 CFR 1250.32 - Food-handling operations.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Food-handling operations. 1250.32 Section 1250.32 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED... operations. (a) All food-handling operations shall be accomplished so as to minimize the possibility of...

  9. 14 CFR 420.65 - Handling of solid propellants.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 4 2010-01-01 2010-01-01 false Handling of solid propellants. 420.65....65 Handling of solid propellants. (a) A launch site operator shall determine the maximum total quantity of solid propellants and other solid explosives by class and division, in accordance with 49...

  10. 48 CFR 1852.211-70 - Packaging, handling, and transportation.

    Science.gov (United States)

    2010-10-01

    ... transportation. 1852.211-70 Section 1852.211-70 Federal Acquisition Regulations System NATIONAL AERONAUTICS AND... and Clauses 1852.211-70 Packaging, handling, and transportation. As prescribed in 1811.404-70, insert the following clause: Packaging, Handling, and Transportation (SEPT 2005) (a) The Contractor...

  11. 8 CFR 207.5 - Waiting lists and priority handling.

    Science.gov (United States)

    2010-01-01

    ... REFUGEES § 207.5 Waiting lists and priority handling. Waiting lists are maintained for each designated refugee group of special humanitarian concern. Each applicant whose application is accepted for filing by... 8 Aliens and Nationality 1 2010-01-01 2010-01-01 false Waiting lists and priority handling....

  12. 24 CFR 3282.256 - Distributor or dealer complaint handling.

    Science.gov (United States)

    2010-04-01

    ... handling. 3282.256 Section 3282.256 Housing and Urban Development Regulations Relating to Housing and Urban... HOUSING AND URBAN DEVELOPMENT MANUFACTURED HOME PROCEDURAL AND ENFORCEMENT REGULATIONS Dealer and Distributor Responsibilities § 3282.256 Distributor or dealer complaint handling. (a) When a distributor...

  13. 7 CFR 97.18 - Applications handled in confidence.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 3 2010-01-01 2010-01-01 false Applications handled in confidence. 97.18 Section 97.18 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING... confidence. (a) Pending applications shall be handled in confidence. Except as provided below, no information...

  14. Development of a gripper for handling and assembly of microscrews

    DEFF Research Database (Denmark)

    Gegeckaite, Asta; Hansen, Hans Nørgaard; Eriksson, Torbjörn

    2006-01-01

    This paper presents the development and design of a gripping tool, able to perform both handling and assembly of microscrews. The gripping tool presented here is a vacuum based gripper interacted with an automatic screwdriver. This construction is used in the handling and assembly of microscrews....

  15. 29 CFR 901.4 - Handling of disputes by Commission.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 4 2010-07-01 2010-07-01 false Handling of disputes by Commission. 901.4 Section 901.4 Labor Regulations Relating to Labor (Continued) CONSTRUCTION INDUSTRY COLLECTIVE BARGAINING COMMISSION POLICY STATEMENT ON COLLECTIVE BARGAINING DISPUTES AND APPLICABLE PROCEDURES § 901.4 Handling of disputes...

  16. Optimal event handling by multiple unmanned aerial vehicles

    NARCIS (Netherlands)

    de Roo, Martijn; Frasca, Paolo; Carloni, Raffaella

    This paper proposes a control architecture for a fleet of unmanned aerial vehicles that is responsible for handling the events that take place in a given area. The architecture guarantees that each event is handled by the required number of vehicles in the shortest time, while the rest of the fleet

  17. Design of liquid container handles in accordance with user preferences.

    Science.gov (United States)

    Jung, H S; Jung, H-S

    2008-03-01

    In this study, a prototype liquid container combined with auxiliary handles was designed to increase the safety of manual handling and to protect users of these containers from hand contamination. A Likert summated rating method as well as a pairwise ranking test was applied to evaluate the user preferences for handles provided for the container under the conditions of different shapes and positions. The results show that the participants preferred perpendicular orientation of the handle on the top of the liquid container while carrying the containers and the crosswise position of the handle at the side of the container while pouring the liquid. In order to satisfy both conditions, the container needs to be designed with handles in perpendicular as well as crosswise positions for selective application. A prototype liquid container with provided auxiliary handles was developed based on the results of the evaluation. It is recommended that a liquid container provides extra handles to reduce musculoskeletal stress and in turn increase user satisfaction.

  18. 46 CFR 151.25-2 - Cargo handling space.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 5 2010-10-01 2010-10-01 false Cargo handling space. 151.25-2 Section 151.25-2 Shipping... BULK LIQUID HAZARDOUS MATERIAL CARGOES Environmental Control § 151.25-2 Cargo handling space. Pump rooms, compressor rooms, refrigeration rooms, heating rooms, instrument rooms or other closed...

  19. Relationships between the renal handling of DMPS and DMSA and the renal handling of mercury.

    Science.gov (United States)

    Zalups, Rudolfs K; Bridges, Christy C

    2012-09-17

    Within the body of this review, we provide updates on the mechanisms involved in the renal handling mercury (Hg) and the vicinal dithiol complexing/chelating agents, 2,3-bis(sulfanyl)propane-1-sulfonate (known formerly as 2,3-dimercaptopropane-1-sulfonate, DMPS) and meso-2,3-bis(sulfanyl)succinate (known formerly as meso-2,3-dimercaptosuccinate, DMSA), with a focus on the therapeutic effects of these dithiols following exposure to different chemical forms of Hg. We begin by reviewing briefly some of the chemical properties of Hg, with an emphasis on the high bonding affinity between mercuric ions and reduced sulfur atoms, principally those contained in protein and nonprotein thiols. A discussion is provided on the current body of knowledge pertaining to the handling of various mercuric species within the kidneys, focusing on the primary cellular targets that take up and are affected adversely by these species of Hg, namely, proximal tubular epithelial cells. Subsequently, we provide a brief update on the current knowledge on the handling of DMPS and DMSA in the kidneys. In particular, parallels are drawn between the mechanisms participating in the uptake of various thiol S-conjugates of Hg in proximal tubular cells and mechanisms by which DMPS and DMSA gain entry into these target epithelial cells. Finally, we discuss factors that permit DMPS and DMSA to bind intracellular mercuric ions and mechanisms transporting DMPS and DMSA S-conjugates of Hg out of proximal tubular epithelial cells into the luminal compartment of the nephron, and promoting urinary excretion.

  20. Segment handling system prototype progress for Thirty Meter Telescope

    Science.gov (United States)

    Sofuku, Satoru; Ezaki, Yutaka; Kawaguchi, Noboru; Nakaoji, Toshitaka; Takaki, Junji; Horiuchi, Yasushi; Saruta, Yusuke; Haruna, Masaki; Kim, Ieyoung; Fukushima, Kazuhiko; Domae, Yukiyasu; Hatta, Toshiyuki; Yoshitake, Shinya; Hoshino, Hayato

    2016-07-01

    Segment Handling System (SHS) is the subsystem that is planned to be permanently implemented on Thirty Meter Telescope (TMT) telescope structure that enables fast, efficient, semi-automatic exchange of M1 segments. TMT plans challenging segment exchange (10 segments per 10 hours a day). To achieve these, MELCO develops innovative SHS by accommodating Factory Automation (FA) technology such as force control system and machine vision system into the system. Force control system used for install operation, achieves soft handling by detecting force exerted to mirror segment and automatically compensating the position error between handling segments and primary mirror. Machine vision system used for removal operation, achieves semi-automatic positioning between SHS and mirror segments to be handled. Prototype experience proves soft (extraneous force 300N) and fast ( 3 minutes) segment handling. The SHS will provide upcoming segmented large telescopes for cost-efficient, effortless, and safe segment exchange operation.

  1. Handling high data rate detectors at Diamond Light Source

    Science.gov (United States)

    Pedersen, U. K.; Rees, N.; Basham, M.; Ferner, F. J. K.

    2013-03-01

    An increasing number of area detectors, in use at Diamond Light Source, produce high rates of data. In order to capture, store and process this data High Performance Computing (HPC) systems have been implemented. This paper will present the architecture and usage for handling high rate data: detector data capture, large volume storage and parallel processing. The EPICS area Detector frame work has been adopted to abstract the detectors for common tasks including live processing, file format and storage. The chosen data format is HDF5 which provides multidimensional data storage and NeXuS compatibility. The storage system and related computing infrastructure include: a centralised Lustre based parallel file system, a dedicated network and a HPC cluster. A well defined roadmap is in place for the evolution of this to meet demand as the requirements and technology advances. For processing the science data the HPC cluster allow efficient parallel computing, on a mixture of ×86 and GPU processing units. The nature of the Lustre storage system in combination with the parallel HDF5 library allow efficient disk I/O during computation jobs. Software developments, which include utilising optimised parallel file reading for a variety of post processing techniques, are being developed in collaboration as part of the Pan-Data EU Project (www.pan-data.eu). These are particularly applicable to tomographic reconstruction and processing of non crystalline diffraction data.

  2. Regulating nanomedicine - can the FDA handle it?

    Science.gov (United States)

    Bawa, Raj

    2011-05-01

    nanomedicine research and development (R&D) and erode public acceptance of nanoproducts. The end-result of this could be a delay or loss of commercialized nanoproducts. Whether the FDA eventually creates new regulations, tweaks existing ones or establishes a new regulatory center to handle nanoproducts, for the time being it should at least look at nanoproducts on a case-by-case basis. The FDA should not attempt regulation of nanomedicine by applying existing statutes alone, especially where scientific evidence suggests otherwise. Incorporating nanomedicine regulation into the current regulatory scheme is a poor idea. Regulation of nanomedicine must balance innovation and R&D with the principle of ensuring maximum public health protection and safety.

  3. Remote-Handled Transuranic Content Codes

    Energy Technology Data Exchange (ETDEWEB)

    Washington TRU Solutions

    2001-08-01

    The Remote-Handled Transuranic (RH-TRU) Content Codes (RH-TRUCON) document representsthe development of a uniform content code system for RH-TRU waste to be transported in the 72-Bcask. It will be used to convert existing waste form numbers, content codes, and site-specificidentification codes into a system that is uniform across the U.S. Department of Energy (DOE) sites.The existing waste codes at the sites can be grouped under uniform content codes without any lossof waste characterization information. The RH-TRUCON document provides an all-encompassing|description for each content code and compiles this information for all DOE sites. Compliance withwaste generation, processing, and certification procedures at the sites (outlined in this document foreach content code) ensures that prohibited waste forms are not present in the waste. The contentcode gives an overall description of the RH-TRU waste material in terms of processes and|packaging, as well as the generation location. This helps to provide cradle-to-grave traceability ofthe waste material so that the various actions required to assess its qualification as payload for the72-B cask can be performed. The content codes also impose restrictions and requirements on themanner in which a payload can be assembled.The RH-TRU Waste Authorized Methods for Payload Control (RH-TRAMPAC), Appendix 1.3.7of the 72-B Cask Safety Analysis Report (SAR), describes the current governing procedures|applicable for the qualification of waste as payload for the 72-B cask. The logic for this|classification is presented in the 72-B Cask SAR. Together, these documents (RH-TRUCON,|RH-TRAMPAC, and relevant sections of the 72-B Cask SAR) present the foundation and|justification for classifying RH-TRU waste into content codes. Only content codes described in thisdocument can be considered for transport in the 72-B cask. Revisions to this document will be madeas additional waste qualifies for transport. |Each content code uniquely

  4. Recommendations for collection and handling of specimens from group breast cancer clinical trials.

    Science.gov (United States)

    Leyland-Jones, Brian R; Ambrosone, Christine B; Bartlett, John; Ellis, Matthew J C; Enos, Rebecca A; Raji, Adekunle; Pins, Michael R; Zujewski, Jo Anne; Hewitt, Stephen M; Forbes, John F; Abramovitz, Mark; Braga, Sofia; Cardoso, Fatima; Harbeck, Nadia; Denkert, Carsten; Jewell, Scott D

    2008-12-01

    Recommendations for specimen collection and handling have been developed for adoption across breast cancer clinical trials conducted by the Breast International Group (BIG)-sponsored Groups and the National Cancer Institute (NCI)-sponsored North American Cooperative Groups. These recommendations are meant to promote identifiable standards for specimen collection and handling within and across breast cancer trials, such that the variability in collection/handling practices that currently exists is minimized and specimen condition and quality are enhanced, thereby maximizing results from specimen-based diagnostic testing and research. Three working groups were formed from the Cooperative Group Banking Committee, BIG groups, and North American breast cancer cooperative groups to identify standards for collection and handling of (1) formalin-fixed, paraffin-embedded (FFPE) tissue; (2) blood and its components; and (3) fresh/frozen tissue from breast cancer trials. The working groups collected standard operating procedures from multiple group specimen banks, administered a survey on banking practices to those banks, and engaged in a series of discussions from 2005 to 2007. Their contributions were synthesized into this document, which focuses primarily on collection and handling of specimens to the point of shipment to the central bank, although also offers some guidance to central banks. Major recommendations include submission of an FFPE block, whole blood, and serial serum or plasma from breast cancer clinical trials, and use of one fixative and buffer type (10% neutral phosphate-buffered formalin, pH 7) for FFPE tissue across trials. Recommendations for proper handling and shipping were developed for blood, serum, plasma, FFPE, and fresh/frozen tissue.

  5. Characterization of aqueous two phase systems by combining lab-on-a-chip technology with robotic liquid handling stations.

    Science.gov (United States)

    Amrhein, Sven; Schwab, Marie-Luise; Hoffmann, Marc; Hubbuch, Jürgen

    2014-11-07

    Over the last decade, the use of design of experiment approaches in combination with fully automated high throughput (HTP) compatible screenings supported by robotic liquid handling stations (LHS), adequate fast analytics and data processing has been developed in the biopharmaceutical industry into a strategy of high throughput process development (HTPD) resulting in lower experimental effort, sample reduction and an overall higher degree of process optimization. Apart from HTP technologies, lab-on-a-chip technology has experienced an enormous growth in the last years and allows further reduction of sample consumption. A combination of LHS and lab-on-a-chip technology is highly desirable and realized in the present work to characterize aqueous two phase systems with respect to tie lines. In particular, a new high throughput compatible approach for the characterization of aqueous two phase systems regarding tie lines by exploiting differences in phase densities is presented. Densities were measured by a standalone micro fluidic liquid density sensor, which was integrated into a liquid handling station by means of a developed generic Tip2World interface. This combination of liquid handling stations and lab-on-a-chip technology enables fast, fully automated, and highly accurate density measurements. The presented approach was used to determine the phase diagram of ATPSs composed of potassium phosphate (pH 7) and polyethylene glycol (PEG) with a molecular weight of 300, 400, 600 and 1000 Da respectively in the presence and in the absence of 3% (w/w) sodium chloride. Considering the whole ATPS characterization process, two complete ATPSs could be characterized within 24h, including four runs per ATPS for binodal curve determination (less than 45 min/run), and tie line determination (less than 45 min/run for ATPS preparation and 8h for density determination), which can be performed fully automated over night without requiring man power. The presented methodology provides

  6. Conceptual design report, plutonium stabilization and handling,project W-460

    Energy Technology Data Exchange (ETDEWEB)

    Weiss, E.V.

    1997-03-06

    Project W-460, Plutonium Stabilization and Handling, encompasses procurement and installation of a Stabilization and Packaging System (SPS) to oxidize and package for long term storage remaining plutonium-bearing special nuclear materials currently in inventory at the Plutonium Finishing Plant (PFP), and modification of vault equipment to allow storage of resulting packages of stabilized SNM for up to fifty years. This Conceptual Design Report (CDR) provides conceptual design details for the vault modification, site preparation and site interface with the purchased SPS. Two concepts are described for vault configuration; acceleration of this phase of the project did not allow completion of analysis which would clearly identify a preferred approach.

  7. Plutonium stabilization and handling (PuSH)

    Energy Technology Data Exchange (ETDEWEB)

    Weiss, E.V.

    1997-01-23

    This Functional Design Criteria (FDC) addresses construction of a Stabilization and Packaging System (SPS) to oxidize and package for long term storage remaining plutonium-bearing special nuclear materials currently in inventory at the Plutonium Finishing Plant (PFP), and modification of vault equipment to allow storage of resulting packages of stabilized SNM for up to fifty years. The major sections of the project are: site preparation; SPS Procurement, Installation, and Testing; storage vault modification; and characterization equipment additions. The SPS will be procured as part of a Department of Energy nationwide common procurement. Specific design crit1460eria for the SPS have been extracted from that contract and are contained in an appendix to this document.

  8. Conceptual design of CFETR divertor remote handling compatible structure

    Energy Technology Data Exchange (ETDEWEB)

    Dai, Huaichu, E-mail: yaodm@ipp.ac.cn [Institute of Plasma Physics, Chinese Academy of Sciences, Hefei 230031 (China); University of Science and Technology of China, Hefei (China); Yao, Damao; Cao, Lei; Zhou, Zibo; Li, Lei [Institute of Plasma Physics, Chinese Academy of Sciences, Hefei 230031 (China)

    2016-11-15

    Highlights: • Conceptual design for the CFETR divertor have been proposed, especially the divertor remote handling compatible structure. • The degrees of freedom of the divertor are analyzed in order to validate the design the divertor supports structure. • Besides the ITER-like scheme, a new scheme for the divertor remote handling compatible supports is proposed, that is the rack and pinion mechanism. • The installation/removel process is verified through simulation in Delmia in order to check design quality for remote handling requirements. - Abstract: Divertor is one of key components of tokamak fusion reactor. The CFETR is China Fusion Engineering Test Reactor. Its divertor will expose to tritium environment and neutron radiation. Materials of the divertor will be radioactived, and cannot be handled by personnel directly. To develop structure which compatible with robots handle for installation, maintenance and removing is required. This paper introduces a conceptual design of CFETR divertor module which compatible with remote handling end-effectors. The divertor module is confined by inner and outer support. The inner support is only confined divertor module radial, toroidal and vertical moving freedom degrees, but not confined rotating freedom degrees. The outer support is the structure that can confine rotating freedom degrees and should also be compatible with remote handling end-effectors.

  9. A practical guide to handling laser diode beams

    CERN Document Server

    Sun, Haiyin

    2015-01-01

    This book offers the reader a practical guide to the control and characterization of laser diode beams.  Laser diodes are the most widely used lasers, accounting for 50% of the global laser market.  Correct handling of laser diode beams is the key to the successful use of laser diodes, and this requires an in-depth understanding of their unique properties. Following a short introduction to the working principles of laser diodes, the book describes the basics of laser diode beams and beam propagation, including Zemax modeling of a Gaussian beam propagating through a lens.  The core of the book is concerned with laser diode beam manipulations: collimating and focusing, circularization and astigmatism correction, coupling into a single mode optical fiber, diffractive optics and beam shaping, and manipulation of multi transverse mode beams.  The final chapter of the book covers beam characterization methods, describing the measurement of spatial and spectral properties, including wavelength and linewidth meas...

  10. Integrated robotic vehicle control system for outdoor container handling

    Science.gov (United States)

    Viitanen, Jouko O.; Haverinen, Janne; Mattila, Pentti; Maekelae, Hannu; von Numers, Thomas; Stanek, Zbigniev; Roening, Juha

    1997-09-01

    We describe an integrated system developed for use onboard a moving work machine. The machine is targeted to such applications as e.g. automatic container handling at loading terminals. The main emphasis is on the various environment perception duties required by autonomous or semi-autonomous operation. These include obstacle detection, container position determination, localization needed for efficient navigation and measurement of docking and grasping locations of containers. Practical experience is reported on the use of several different types of technologies for the tasks. For close distance measurement, such as container row following, ultrasonic measurement was used, with associated control software. For obstacle and docking position detection, 3D active vision techniques were developed with structured lighting, utilizing also motion estimation techniques. Depth from defocus-based methods were developed for passive 3D vision. For localization, fusion of data from several sources was carried out. These included dead-reckoning data from odometry, an inertial unit, and several alternative external localization devices, i.e. real-time kinematic GPS, inductive and optical transponders. The system was integrated to run on a real-time operating system platform, using a high-level software specification tool that created the hierarchical control structure of the software.

  11. Early handling modulates outcome of neonatal dexamethasone exposure.

    Science.gov (United States)

    Claessens, Sanne E F; Daskalakis, Nikolaos P; Oitzl, Melly S; de Kloet, E Ronald

    2012-09-01

    Synthetic glucocorticoids such as dexamethasone (DEX) are used to prevent or treat respiratory disorders in prematurely born infants. Besides the short-term benefit on lung development, numerous human and animal studies have reported adverse neurodevelopmental side effects. In contrast, maternal care is known to exert a positive influence on neurodevelopmental outcome in rodents. The aim of the current study was therefore to investigate whether neonatal handling (days 1-21), known to induce maternal care, might serve as an intervention strategy modulating the adverse effects of DEX treatment (days 1-3). For this purpose we have measured the outcome of these early-life manipulations on development as well as adult endocrine and behavioral phenotype of male rats. Maternal care was observed during the first week of life and indeed enhanced in response to handling. Eye opening was accelerated and body weight reduced in DEX-treated animals. In adulthood, we report that handling ameliorated impaired spatial learning observed in DEX treated non-handled animals in the T-maze. Additionally, handling reduced susceptibility to the impact of DEX treatment in the water maze. Although DEX treatment and handling both resulted in enhanced negative feedback of the stress-induced corticosterone response and both reduced startle reactivity, the acquisition of fear was only reduced by handling, without effect of DEX. Interestingly, handling had a beneficial effect on pre-pulse inhibition, which was diminished after DEX treatment. In conclusion, these findings indicate that handling of the neonate enhances maternal care and attenuates specific DEX-induced alterations in the adult behavioral phenotype. Copyright © 2012 Elsevier Inc. All rights reserved.

  12. Rational Handling of Multiple Goals for Mobile Robots

    Science.gov (United States)

    1993-11-01

    AD.-A273 733 V * ~ 1. K ~Rational Handling of Multiple Goals for Mobile Robots Richard Goodwin Reid Simmons November 1, 1993. CM-S-93-204 ... I.f it...8217A ~~DEC99 oilsi VI-uI Best Available Copy Radonal Handling of Multiple Goals for Mobile Robots Richard Goodwin Reid Sinnos November 1, 1993 CMU-€S-93...Engineering Research Council of Canada. 93 12 8, 081 1 Introduction This report examines a method for handling multiple active goals for mobile robots . Specifically

  13. Handling alters aggression and "loser" effect formation in Drosophila melanogaster.

    Science.gov (United States)

    Trannoy, Severine; Chowdhury, Budhaditya; Kravitz, Edward A

    2015-02-01

    In Drosophila, prior fighting experience influences the outcome of later contests: losing a fight increases the probability of losing second contests, thereby revealing "loser" effects that involve learning and memory. In these experiments, to generate and quantify the behavioral changes observed as consequences of losing fights, we developed a new behavioral arena that eliminates handling. We compared two commonly used fly handling procedures with this new chamber and demonstrated that handling influences aggressive behavior and prevents "loser" effect formation. In addition, we induced and observed novel aspects of learning associated with aggression such as the formation of robust winner effects. Published by Cold Spring Harbor Laboratory Press.

  14. Ergonomic T-Handle for Minimally Invasive Surgical Instruments.

    Science.gov (United States)

    Parekh, J; Shepherd, Det; Hukins, Dwl; Maffulli, N

    2016-05-01

    A T-handle has been designed to be used for minimally invasive implantation of a dynamic hip screw to repair fractures of the proximal femur. It is capable of being used in two actions: (i) push and hold (while using an angle guide) and (ii) application of torque when using the insertion wrench and lag screw tap. The T-handle can be held in a power or precision grip. It is suitable for either single (sterilised by γ-irradiation) or multiple (sterilised by autoclaving) use. The principles developed here are applicable to handles for a wide range of surgical instruments.

  15. Eco Issues in Bulk Materials Handling Technologies in Ports

    Directory of Open Access Journals (Sweden)

    Nenad Zrnić

    2011-09-01

    Full Text Available This paper deals with eco issues in bulk materials handling in ports. Solid, free-flowing materials are said to be in bulk. Bulk materials handling is very difficult, because it incorporates all the features of liquids, gasses and mass solids. Energy efficiency, dust emissions in nearby environment, dust explosions, jamming, noise, handling of hazardous materials and protection of materials from contamination are issues that will be considered in this paper. Here are also presented possible solutions for some of these issues

  16. Design Study and Animation on an Integrated In-Vessel Fuel Handling and Inspection System in a SFR

    Energy Technology Data Exchange (ETDEWEB)

    Kim, S. H.; Joo, Y. S.; Lee, J. H. [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2009-05-15

    The fuel handling system includes several major components including the rotating plug, in-vessel fuel handling machine, storage rack, cask transporter. The in-vessel fuel handling machine provides access to any core position by means of the eccentric rotating plugs supported in the reactor head. The reactor core and mechanical components which make up the primary circuit coolant are fully immersed in sodium, with the core being up to several meters below the sodium surface. Examination of the internal structure is therefore a difficult task. For example, visual techniques are impossible because of the opacity of liquid metal, and a lowering of the sodium level is impractical once a reactor is operational. In this study, the concept of an integrated fuel handling and inspection machine was suggested to enhance the effectiveness and application of an in-vessel fuel handling machine, and the alternative concept of a specially designed indexing machine has been reviewed and compared. Also, the concept of an integrated in-vessel fuel handling and inspection system was made as a 3D computer graphic animation which is easy to understand the driving characteristics to inform of the design result and verify the design adequacy through the technical consultation of the expert.

  17. Data handling for the lepton detector

    Energy Technology Data Exchange (ETDEWEB)

    Cutts, D.; Droege, T.F.; Kasha, H.; Kirsch, L.E.; Littenberg, L.; Matthews, J.A.J.; Rabin, M.S.Z.; Scharenguivel, J.

    1978-01-01

    The data acquisition and processing needs of a typical lepton-oriented large-solid-angle detector were evaluated, and a configuration of the data readout systems (including microprocessors), control computer(s), and local intersection computer was recommended. Features considered explicitly include triggering and data rates, data readout and monitoring (standard device processor, event processor, and intersection event processor), and off-line computing. 6 figures, 2 tables. (RWR)

  18. Solution preparation

    Energy Technology Data Exchange (ETDEWEB)

    Seitz, M.G.

    1982-01-01

    Reviewed in this statement are methods of preparing solutions to be used in laboratory experiments to examine technical issues related to the safe disposal of nuclear waste from power generation. Each approach currently used to prepare solutions has advantages and any one approach may be preferred over the others in particular situations, depending upon the goals of the experimental program. These advantages are highlighted herein for three approaches to solution preparation that are currently used most in studies of nuclear waste disposal. Discussion of the disadvantages of each approach is presented to help a user select a preparation method for his particular studies. Also presented in this statement are general observations regarding solution preparation. These observations are used as examples of the types of concerns that need to be addressed regarding solution preparation. As shown by these examples, prior to experimentation or chemical analyses, laboratory techniques based on scientific knowledge of solutions can be applied to solutions, often resulting in great improvement in the usefulness of results.

  19. Microphone Handling Noise: Measurements of Perceptual Threshold and Effects on Audio Quality.

    Directory of Open Access Journals (Sweden)

    Paul Kendrick

    Full Text Available A psychoacoustic experiment was carried out to test the effects of microphone handling noise on perceived audio quality. Handling noise is a problem affecting both amateurs using their smartphones and cameras, as well as professionals using separate microphones and digital recorders. The noises used for the tests were measured from a variety of devices, including smartphones, laptops and handheld microphones. The signal features that characterise these noises are analysed and presented. The sounds include various types of transient, impact noises created by tapping or knocking devices, as well as more sustained sounds caused by rubbing. During the perceptual tests, listeners auditioned speech podcasts and were asked to rate the degradation of any unwanted sounds they heard. A representative design test methodology was developed that tried to encourage everyday rather than analytical listening. Signal-to-noise ratio (SNR of the handling noise events was shown to be the best predictor of quality degradation. Other factors such as noise type or background noise in the listening environment did not significantly affect quality ratings. Podcast, microphone type and reproduction equipment were found to be significant but only to a small extent. A model allowing the prediction of degradation from the SNR is presented. The SNR threshold at which 50% of subjects noticed handling noise was found to be 4.2 ± 0.6 dBA. The results from this work are important for the understanding of our perception of impact sound and resonant noises in recordings, and will inform the future development of an automated predictor of quality for handling noise.

  20. Microphone Handling Noise: Measurements of Perceptual Threshold and Effects on Audio Quality.

    Science.gov (United States)

    Kendrick, Paul; Jackson, Iain R; Fazenda, Bruno M; Cox, Trevor J; Li, Francis F

    2015-01-01

    A psychoacoustic experiment was carried out to test the effects of microphone handling noise on perceived audio quality. Handling noise is a problem affecting both amateurs using their smartphones and cameras, as well as professionals using separate microphones and digital recorders. The noises used for the tests were measured from a variety of devices, including smartphones, laptops and handheld microphones. The signal features that characterise these noises are analysed and presented. The sounds include various types of transient, impact noises created by tapping or knocking devices, as well as more sustained sounds caused by rubbing. During the perceptual tests, listeners auditioned speech podcasts and were asked to rate the degradation of any unwanted sounds they heard. A representative design test methodology was developed that tried to encourage everyday rather than analytical listening. Signal-to-noise ratio (SNR) of the handling noise events was shown to be the best predictor of quality degradation. Other factors such as noise type or background noise in the listening environment did not significantly affect quality ratings. Podcast, microphone type and reproduction equipment were found to be significant but only to a small extent. A model allowing the prediction of degradation from the SNR is presented. The SNR threshold at which 50% of subjects noticed handling noise was found to be 4.2 ± 0.6 dBA. The results from this work are important for the understanding of our perception of impact sound and resonant noises in recordings, and will inform the future development of an automated predictor of quality for handling noise.

  1. Bucket handle tears of the medial meniscus: meniscal intrusion rather than meniscal extrusion

    Energy Technology Data Exchange (ETDEWEB)

    Schlossberg, S. [Jacobi Medical Center, Department of Radiology, Bronx, NY (United States); Umans, H. [Jacobi Medical Center, Department of Radiology, Bronx, NY (United States); Jacobi Medical Center, Department of Surgery Division of Orthopedic Surgery, Bronx, NY (United States); Flusser, G. [Tel Aviv Sourasky Medical Center, Department of Radiology, Tel Aviv (Israel); DiFelice, G.S. [Jacobi Medical Center, Department of Surgery Division of Orthopedic Surgery, Bronx, NY (United States); Lerer, D.B. [Montefiore Medical Center, Department of Radiology, Bronx, NY (United States)

    2007-01-15

    To determine the frequency of medial meniscal extrusion (MME) versus ''medial meniscal intrusion'' in the setting of bucket handle tears. Images were evaluated for previously reported risk factors for MME, including: medial meniscal root tear, radial tear, degenerative joint disease and joint effusion. Forty-one consecutive cases of bucket handle tear of the medial meniscus were reviewed by consensus by two musculoskeletal radiologists. Imaging was performed using a 1.5 GE Signa MR unit. Patient age, gender, medial meniscal root integrity, MME, medial meniscal intrusion, degenerative joint disease, effusion and anterior cruciate ligament (ACL) tear were recorded. Thirteen females and 27 males (age 12-62 years, median=30 years) were affected; one had bucket handle tear of each knee. Effusion was small in 13, moderate in 9 and large in 18. Degenerative joint disease was mild in three, moderate in two and severe in one. 26 ACL tears included three partial and three chronic. Medial meniscal root tear was complete in one case and partial thickness in two. None of the 40 cases with an intact or partially torn medial meniscal root demonstrated MME. MME of 3.1 mm was seen in the only full-thickness medial meniscal root tear, along with chronic ACL tear, moderate degenerative joint disease and large effusion. Medial meniscal intrusion of the central bucket handle fragment into the intercondylar notch was present in all 41 cases. Given an intact medial meniscal root in the setting of a ''pure'' bucket handle tear, there is no MME. (orig.)

  2. Review of US Navy VSTOL handling qualities requirements

    Science.gov (United States)

    Hutchings, D. E.

    1977-01-01

    Handling qualities requirements for V/STOL operations from small ships are considered in terms of the ship operating environment. Turbulence, wind over the deck, ship motion, visibility, and severe weather and sea conditions are among the factors discussed.

  3. PRN 73-4: Residual Insecticides in Food Handling Establishments

    Science.gov (United States)

    This notice provides a copy of a Federal Register notice published July 6, 1973, regarding certain insecticides used in food-handling establishments. It establishes certain definitions and requirements related to approval for crack and crevice treatment.

  4. Apparatus for handling micron size range particulate material

    Science.gov (United States)

    Friichtenicht, J. F.; Roy, N. L. (Inventor)

    1968-01-01

    An apparatus for handling, transporting, or size classifying comminuted material was described in detail. Electrostatic acceleration techniques for classifying particles as to size in the particle range from 0.1 to about 100 microns diameter were employed.

  5. How the visual cortex handles stimulus noise: insights from amblyopia

    National Research Council Canada - National Science Library

    Bankó, Éva M; Körtvélyes, Judit; Weiss, Béla; Vidnyánszky, Zoltán

    2013-01-01

    .... However, visual cortical processes directly involved in handling the stimulus noise have yet to be identified and dissociated from the modulation of the neural responses due to the deteriorated...

  6. Hospital Protocol RSD/CRPS Patient: Handle with Care!

    Science.gov (United States)

    Hospital Protocol  RSD/CRPS Patients: Handle With Care! Reflex Sympathetic Dystrophy (RSD) also known as Complex Regional ... taken care of solely through use of the hospital’s pharmacy. Some medications may not be part of ...

  7. Redefining NHS complaint handling--the real challenge.

    Science.gov (United States)

    Seelos, L; Adamson, C

    1994-01-01

    More and more organizations find that a constructive and open dialogue with their customers can be an effective strategy for building long-term customer relations. In this context, it has been recognized that effective complaint-contact handling can make a significant contribution to organizations' attempts to maximize customer satisfaction and loyalty. Within the NHS, an intellectual awareness exists that effective complaint/contact handling can contribute to making services more efficient and cost-effective by developing customer-oriented improvement initiatives. Recent efforts have focused on redefining NHS complaint-handling procedures to make them more user-friendly and effective for both NHS employees and customers. Discusses the challenges associated with opening up the NHS to customer feedback. Highlights potential weaknesses in the current approach and argues that the real challenge is for NHS managers to facilitate a culture change that moves the NHS away from a long-established defensive complaint handling practice.

  8. Uncertainty Handling in Remote Sensing Data Analysis for Defence

    OpenAIRE

    D. P. Mandal; Murthy, C. A.; Pal, S K

    1995-01-01

    Describes a way of handling uncertainty in IRS imagery by utilising a multivalued recognition system. Roads and bridges can be detected effectively by using the multiple class choices provided by the multivalued recognition system.

  9. Evaluation of fish handling techniques employed by artisanal fishers ...

    African Journals Online (AJOL)

    Evaluation of fish handling techniques employed by artisanal fishers on quality of ... genera at landing time along the Kenyan coast using sensory and microbiological methods. ... African Journal of Food, Agriculture, Nutrition and Development.

  10. Optimal handle angle of the fencing foil for improved performance.

    Science.gov (United States)

    Lin, Fang-Tsan

    2004-06-01

    Improperly designed hand tools and sports equipment contribute to undesired injuries and accidents. The idea of bending the tool, not the wrist, has been applied to sports equipment. According to Bennett's idea, the design of an ideal handle angle should be in the range of 14 degrees to 24 degrees. Thus design of the handle angle in the sport of fencing is also important. A well-designed handle angle could not only reduce ulnar deviation to avoid wrist injury but also enhance performance. An experiment with several different handle angles was conducted to analyze the effect on performance. Analysis showed an angle of 18 degrees to 21 degrees provided best overall performance in fencing.

  11. Ethical Infrastructure and Successful Handling of Workplace Bullying

    Directory of Open Access Journals (Sweden)

    Kari Einarsen

    2017-03-01

    Full Text Available Antecedents and consequences of workplace bullying are well documented. However, the mea- sures taken against workplace bullying, and the effectiveness of such measures, have received less attention. This study addresses this knowledge gap by exploring the role of ethical infrastructure in perceived successful handling of reported workplace bullying. Ethical infrastructure refers to formal and informal systems that enable ethical behavior and disable unethical behavior in organizations. A survey was sent to HR managers and elected head safety representatives (HSRs in all Norwegian municipality organizations. Overall, 216 organizations responded (response rate = 50.2 percent. The ethical infrastructure accounted for 39.4% of the variance in perceived suc- cessful handling of workplace bullying. Formal sanctions were the only unique and signi cant contributor to the perceived successful handling of workplace bullying. The results substantiate the argument that organizations’ ethical infrastructure relate to the HR managers and HSRs’ percep- tions regarding their organizations’ handling of workplace bullying.

  12. Infection Control: The Use and Handling of Toothbrushes

    Science.gov (United States)

    ... for Infection Control The Use and Handling of Toothbrushes Recommend on Facebook Tweet Share Compartir Infection Control ... Recommended Toothbrush Care Toothbrushing in Group Settings Recommended Toothbrush Care Do not share toothbrushes. The exchange of ...

  13. Physical properties of fertilizer in relation to handling and spreading.

    NARCIS (Netherlands)

    Hofstee, J.W.

    1993-01-01

    The influence of physical properties of fertilizer on the handling and spreading is studied. The reviewed properties are particle size and particle size distribution, coefficient of friction, coefficient of restitution, particle strength and aerodynamic resistance. Further a measuring procedure base

  14. PRIME VALUE METHOD TO PRIORITIZE RISK HANDLING STRATEGIES

    Energy Technology Data Exchange (ETDEWEB)

    Noller, D

    2007-10-31

    Funding for implementing risk handling strategies typically is allocated according to either the risk-averse approach (the worst risk first) or the cost-effective approach (the greatest risk reduction per implementation dollar first). This paper introduces a prime value approach in which risk handling strategies are prioritized according to how nearly they meet the goals of the organization that disburses funds for risk handling. The prime value approach factors in the importance of the project in which the risk has been identified, elements of both risk-averse and cost-effective approaches, and the time period in which the risk could happen. This paper also presents a prioritizer spreadsheet, which employs weighted criteria to calculate a relative rank for the handling strategy of each risk evaluated.

  15. Spent nuclear fuel retrieval system fuel handling development testing. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Jackson, D.R.; Meeuwsen, P.V.

    1997-09-01

    Fuel handling development testing was performed in support of the Fuel Retrieval System (FRS) Sub-Project, a subtask of the Spent Nuclear Fuel Project at the Hanford Site in Richland, Washington. The FRS will be used to retrieve and repackage K-Basin Spent Nuclear Fuel (SNF) currently stored in old K-Plant storage basins. The FRS is required to retrieve full fuel canisters from the basin, clean the fuel elements inside the canister to remove excessive uranium corrosion products (or sludge), remove the contents from the canisters and sort the resulting debris, scrap, and fuel for repackaging. The fuel elements and scrap will be collected in fuel storage and scrap baskets in preparation for loading into a multi canister overpack (MCO), while the debris is loaded into a debris bin and disposed of as solid waste. This report describes fuel handling development testing performed from May 1, 1997 through the end of August 1997. Testing during this period was mainly focused on performance of a Schilling Robotic Systems` Conan manipulator used to simulate a custom designed version, labeled Konan, being fabricated for K-Basin deployment. In addition to the manipulator, the camera viewing system, process table layout, and fuel handling processes were evaluated. The Conan test manipulator was installed and fully functional for testing in early 1997. Formal testing began May 1. The purposes of fuel handling development testing were to provide proof of concept and criteria, optimize equipment layout, initialize the process definition, and identify special needs/tools and required design changes to support development of the performance specification. The test program was set up to accomplish these objectives through cold (non-radiological) development testing using simulated and prototype equipment.

  16. Manual handling as risk factor of low back pain among workers

    Directory of Open Access Journals (Sweden)

    Ridwan Harrianto

    2016-02-01

    Full Text Available Disorders of the musculoskeletal system constitute a considerable health problem in industrialized societies. Low back pain (LBP remains a common and costly problem among the workers. Workplace injuries, primarily musculoskeletal disorders, are a persistent problem for nursing. A cross-sectional study was conducted to investigate prevalence of LBP as well as the potential risk factors associated with LBP. These potential risk factors include individual characteristics, job duration, type of work, and manual handling knowledge and practice. Seventy-six subjects consisting of 30 nurses and 46 administrative workers were recruited into the study. Symptoms of LBP cases were assessed by means of a simple questionnaire, and the diagnosis of LBP was confirmed by clinical examination. The study showed that the overall point prevalence rate of LBP was 42.1%, while the overall 12-month prevalence rate was 69.7%. Occupational group and manual handling practice were independent predictors for point prevalence of LBP. Nursing occupation significantly increased the risk of point prevalence rate of LBP by 2.703 (95% C.I. OR 1.046 – 6.984 compared to administrative workers. Nurses with frequent manual handling practice had a 2.917-fold higher risk of developing a point prevalence of LBP, although this risk was statistically not significant (OR=2.917;95% C.I. 0.094-3.003. The study indicates that an association exists between manual handling practice and LBP prevalence.

  17. Manual handling as risk factor of low back pain among workers

    Directory of Open Access Journals (Sweden)

    Ridwan Harrianto

    2009-12-01

    Full Text Available Disorders of the musculoskeletal system constitute a considerable health problem in industrialized societies. Low back pain (LBP remains a common and costly problem among the workers. Workplace injuries, primarily musculoskeletal disorders, are a persistent problem for nursing. A cross-sectional study was conducted to investigate prevalence of LBP as well as the potential risk factors associated with LBP. These potential risk factors include individual characteristics, job duration, type of work, and manual handling knowledge and practice. Seventy-six subjects consisting of 30 nurses and 46 administrative workers were recruited into the study. Symptoms of LBP cases were assessed by means of a simple questionnaire, and the diagnosis of LBP was confirmed by clinical examination. The study showed that the overall point prevalence rate of LBP was 42.1%, while the overall 12-month prevalence rate was 69.7%. Occupational group and manual handling practice were independent predictors for point prevalence of LBP. Nursing occupation significantly increased the risk of point prevalence rate of LBP by 2.703 (95% C.I. OR 1.046 – 6.984 compared to administrative workers. Nurses with frequent manual handling practice had a 2.917-fold higher risk of developing a point prevalence of LBP, although this risk was statistically not significant (OR=2.917;95% C.I. 0.094-3.003. The study indicates that an association exists between manual handling practice and LBP prevalence.

  18. The Vermicelli Handling Test: A Simple Quantitative Measure of Dexterous Forepaw Function in Rats

    Science.gov (United States)

    Allred, Rachel P.; Adkins, DeAnna L.; Woodlee, Martin T.; Husbands, Lincoln C.; Maldonado, Mónica A.; Kane, Jacqueline R.; Schallert, Timothy; Jones, Theresa A.

    2008-01-01

    Loss of function in the hands occurs with many brain disorders, but there are few measures of skillful forepaw use in rats available to model these impairments that are both sensitive and simple to administer. Whishaw and Coles (1996) previously described the dexterous manner in which rats manipulate food items with their paws, including thin pieces of pasta. We set out to develop a measure of this food handling behavior that would be quantitative, easy to administer, sensitive to the effects of damage to sensory and motor systems of the CNS and useful for identifying the side of lateralized impairments. When rats handle 7 cm lengths of vermicelli, they manipulate the pasta by repeatedly adjusting the forepaw hold on the pasta piece. As operationally defined, these adjustments can be easily identified and counted by an experimenter without specialized equipment. After unilateral sensorimotor cortex (SMC) lesions, transient middle cerebral artery occlusion (MCAO) and striatal dopamine depleting (6-hydroxydopamine, 6-OHDA) lesions in adult rats, there were enduring reductions in adjustments made with the contralateral forepaw. Additional pasta handling characteristics distinguished between the lesion types. MCAO and 6-OHDA lesions increased the frequency of several identified atypical handling patterns. Severe dopamine depletion increased eating time and adjustments made with the ipsilateral forepaw. However, contralateral forepaw adjustment number most sensitively detected enduring impairments across lesion types. Because of its ease of administration and sensitivity to lateralized impairments in skilled forepaw use, this measure may be useful in rat models of upper extremity impairment. PMID:18325597

  19. Mutant Huntingtin and Elusive Defects in Oxidative Metabolism and Mitochondrial Calcium Handling.

    Science.gov (United States)

    Brustovetsky, Nickolay

    2016-07-01

    Elongation of a polyglutamine (polyQ) stretch in huntingtin protein (Htt) is linked to Huntington's disease (HD) pathogenesis. The mutation in Htt correlates with neuronal dysfunction in the striatum and cerebral cortex and eventually leads to neuronal cell death. The exact mechanisms of the injurious effect of mutant Htt (mHtt) on neurons are not completely understood but might include aberrant gene transcription, defective autophagy, abnormal mitochondrial biogenesis, anomalous mitochondrial dynamics, and trafficking. In addition, deficiency in oxidative metabolism and defects in mitochondrial Ca(2+) handling are considered essential contributing factors to neuronal dysfunction in HD and, consequently, in HD pathogenesis. Since the discovery of the mutation in Htt, the questions whether mHtt affects oxidative metabolism and mitochondrial Ca(2+) handling and, if it does, what mechanisms could be involved were in focus of numerous investigations. However, despite significant research efforts, the detrimental effect of mHtt and the mechanisms by which mHtt might impair oxidative metabolism and mitochondrial Ca(2+) handling remain elusive. In this paper, I will briefly review studies aimed at clarifying the consequences of mHtt interaction with mitochondria and discuss experimental results supporting or arguing against the mHtt effects on oxidative metabolism and mitochondrial Ca(2+) handling.

  20. A study of handling cytotoxic drugs and risk of birth defects in offspring of female veterinarians.

    Science.gov (United States)

    Shirangi, Adeleh; Bower, Carol; Holman, C D'Arcy J; Preen, David B; Bruce, Neville

    2014-06-12

    We examined the association of occupational exposure to handling cytotoxic drugs at work with risk of birth defects among a cohort of female veterinarians. This study is a follow up survey of 321 female participants (633 pregnancies) who participated in the Health Risks of Australian Veterinarian project. Data on pregnancies and exposure during each pregnancy was obtained by self-administered mailed questionnaire. Female veterinarians handling cytotoxic drugs during their pregnancy had a two-fold increased risk of birth defects in their offspring (RR = 2.08, 95% CI (1.05-4.15)). Results were consistent in subgroup analysis of those who graduated during the period of 1961 to 1980 (RR = 5.04, 95% CI (1.81, 14.03) and in those working specifically in small and large animal practice. There was no increased risk in the subgroup that graduated after 1980. Women with unplanned pregnancies were more likely to handle cytotoxic drugs on a daily basis (RR = 1.86, 95% CI, 1.00-3.48) and had a higher increased risk of birth defects than those who planned their pregnancies in recent graduates and in those who worked specifically in small animal practice (RR = 2.53, 95% CI, 1.18-5.42). This study suggests that the adverse effects of handling cytotoxic drugs in pregnant women may include an increased risk of birth defects. Pregnancy intention status is an important health behavior and should be considered in prenatal programs.

  1. Safe moving and handling of patients: an interprofessional approach.

    Science.gov (United States)

    Anderson, Matthew P; Carlisle, Susan; Thomson, Clare; Ross, Catherine; Reid, Helen J; Hart, Nigel D; Clarke, Angela

    2014-07-21

    A gap in the medical undergraduate curriculum on safe moving and handling of patients was identified, and a project to enhance moving and handling education for undergraduates in various healthcare disciplines was undertaken. A team of nurses, doctors, physiotherapists and e-learning professionals developed a cross-discipline e-learning resource, piloted with medical and nursing students at Queen's University Belfast. One outcome of the project was the development of a deeper recognition of the common curriculum across healthcare disciplines.

  2. The prevention and handling of the missing data

    OpenAIRE

    Kang, Hyun

    2013-01-01

    Even in a well-designed and controlled study, missing data occurs in almost all research. Missing data can reduce the statistical power of a study and can produce biased estimates, leading to invalid conclusions. This manuscript reviews the problems and types of missing data, along with the techniques for handling missing data. The mechanisms by which missing data occurs are illustrated, and the methods for handling the missing data are discussed. The paper concludes with recommendations for ...

  3. SLSF loop handling system. Volume I. Structural analysis. [LMFBR

    Energy Technology Data Exchange (ETDEWEB)

    Ahmed, H.; Cowie, A.; Ma, D.

    1978-10-01

    SLSF loop handling system was analyzed for deadweight and postulated dynamic loading conditions, identified in Chapters II and III in Volume I of this report, using a linear elastic static equivalent method of stress analysis. Stress analysis of the loop handling machine is presented in Volume I of this report. Chapter VII in Volume I of this report is a contribution by EG and G Co., who performed the work under ANL supervision.

  4. String loop corrections from fusion of handles and vertex operators

    Science.gov (United States)

    Ooguri, H.; Sakai, N.

    1987-10-01

    Handle operators are introduced to describe nonlinear sigma models on higher genus surfaces by an operator formalism. Operator product expansions (fusions) among handle and vertex operators provide new sources of conformal symmetry breakings. Through the renormalization group equations, string-loop corrected equations of motion without one-particle reducible parts are derived to one-loop order. Work supported in part by Grant-in-Aid for Scientific Research from the Ministry of Education, Science and Culture (No. 61540200).

  5. Data handling in cross-cultural studies

    DEFF Research Database (Denmark)

    Scholderer, Joachim

    2010-01-01

    Sound marketing research can significantly reduce the risk associated with new product decisions. In a globalised economy, this often requires the collection of market and consumer data across different countries, cultures, and language communities. However, are such data actually comparable? Thi......, model specification, estimation, testing, and interpretation. The chapter includes a worked example, complete with command syntax for three different software packages.......? This chapter will familiarise the reader with a set of statistical techniques by which the cross-cultural comparability of data - their measurement invariance - can explicitly be assessed. The statistical framework (multi-group confirmatory factor analysis) is described in detail, including data requirements...

  6. Yeast prions: structure, biology, and prion-handling systems.

    Science.gov (United States)

    Wickner, Reed B; Shewmaker, Frank P; Bateman, David A; Edskes, Herman K; Gorkovskiy, Anton; Dayani, Yaron; Bezsonov, Evgeny E

    2015-03-01

    A prion is an infectious protein horizontally transmitting a disease or trait without a required nucleic acid. Yeast and fungal prions are nonchromosomal genes composed of protein, generally an altered form of a protein that catalyzes the same alteration of the protein. Yeast prions are thus transmitted both vertically (as genes composed of protein) and horizontally (as infectious proteins, or prions). Formation of amyloids (linear ordered β-sheet-rich protein aggregates with β-strands perpendicular to the long axis of the filament) underlies most yeast and fungal prions, and a single prion protein can have any of several distinct self-propagating amyloid forms with different biological properties (prion variants). Here we review the mechanism of faithful templating of protein conformation, the biological roles of these prions, and their interactions with cellular chaperones, the Btn2 and Cur1 aggregate-handling systems, and other cellular factors governing prion generation and propagation. Human amyloidoses include the PrP-based prion conditions and many other, more common amyloid-based diseases, several of which show prion-like features. Yeast prions increasingly are serving as models for the understanding and treatment of many mammalian amyloidoses. Patients with different clinical pictures of the same amyloidosis may be the equivalent of yeasts with different prion variants.

  7. Stereo matching with Mumford-Shah regularization and occlusion handling.

    Science.gov (United States)

    Ben-Ari, Rami; Sochen, Nir

    2010-11-01

    This paper addresses the problem of correspondence establishment in binocular stereo vision. We suggest a novel spatially continuous approach for stereo matching based on the variational framework. The proposed method suggests a unique regularization term based on Mumford-Shah functional for discontinuity preserving, combined with a new energy functional for occlusion handling. The evaluation process is based on concurrent minimization of two coupled energy functionals, one for domain segmentation (occluded versus visible) and the other for disparity evaluation. In addition to a dense disparity map, our method also provides an estimation for the half-occlusion domain and a discontinuity function allocating the disparity/depth boundaries. Two new constraints are introduced improving the revealed discontinuity map. The experimental tests include a wide range of real data sets from the Middlebury stereo database. The results demonstrate the capability of our method in calculating an accurate disparity function with sharp discontinuities and occlusion map recovery. Significant improvements are shown compared to a recently published variational stereo approach. A comparison on the Middlebury stereo benchmark with subpixel accuracies shows that our method is currently among the top-ranked stereo matching algorithms.

  8. Conceptual design of Blanket Remote Handling System for CFETR

    Energy Technology Data Exchange (ETDEWEB)

    Wei, Jianghua, E-mail: weijh@ipp.ac.cn [Institute of Plasma Physics, Chinese Academy of Sciences, Hefei (China); Song, Yuntao, E-mail: songyt@ipp.ac.cn [Institute of Plasma Physics, Chinese Academy of Sciences, Hefei (China); University of Science and Technology of China, Hefei (China); Pei, Kun; Zhao, Wenlong; Zhang, Yu; Cheng, Yong [Institute of Plasma Physics, Chinese Academy of Sciences, Hefei (China)

    2015-11-15

    Highlights: • The concept for the blanket maintenance is carried out, including three sub-systems. • The basic maintenance procedure for blanket between VV and hot cell is carried out. • The primary kinematics study is used to verify the feasibility of BRHS. • Virtual reality is adopted as another approach to verify the concept design. - Abstract: The China Fusion Engineering Testing Reactor (CFETR), which is a new superconducting tokamak device being designed by China, has a mission to achieve a high duty time (0.3–0.5). To accomplish this great mission, the big modular blanket option has been adopted to achieve the high efficiency of the blanket maintenance. Considering this mission and the large and heavy blanket module, a novel conceptual blanket maintenance system for CFETR has been carried out by us over the past year. This paper presents the conceptual design of the Blanket Remote Handling System (BRHS), which mainly comprises the In-Vessel-Maintenance-System (IVMS), Lifting System and Blanket-Tool-Manipulator System (BTMS). The BRHS implements the extraction and replacement between in-vessel (the blanket module operation configuration location) and ex-vessel (inside of the vertical maintenance cask) by the collaboration of these three sub systems. What is more, this paper represents the blanket maintenance procedure between the docking station (between hot cell building and tokamak building) and inside the vacuum vessel, in tokamak building. Virtual reality technology is also used to verify and optimize our concept design.

  9. Neonatal handling induces anovulatory estrous cycles in rats

    Directory of Open Access Journals (Sweden)

    Gomes C.M.

    1999-01-01

    Full Text Available Since previous work has shown that stimulation early in life decreases sexual receptiveness as measured by the female lordosis quotient, we suggested that neonatal handling could affect the function of the hypothalamus-pituitary-gonadal axis. The effects of neonatal handling on the estrous cycle and ovulation were analyzed in adult rats. Two groups of animals were studied: intact (no manipulation, N = 10 and handled (N = 11. Pups were either handled daily for 1 min during the first 10 days of life or left undisturbed. At the age of 90 days, a vaginal smear was collected daily at 9:00 a.m. and analyzed for 29 days; at 9:00 a.m. on the day of estrus, animals were anesthetized with thiopental (40 mg/kg, ip, the ovaries were removed and the oviduct was dissected and squashed between 2 glass slides. The number of oocytes of both oviductal ampullae was counted under the microscope. The average numbers for each phase of the cycle (diestrus I, diestrus II, proestrus and estrus during the period analyzed were compared between the two groups. There were no significant differences between intact and handled females during any of the phases. However, the number of handled females that showed anovulatory cycles (8 out of 11 was significantly higher than in the intact group (none out of 10. Neonatal stimulation may affect not only the hypothalamus-pituitary-adrenal axis, as previously demonstrated, but also the hypothalamus-pituitary-gonadal axis in female rats.

  10. Preparing the ground for an operational handling of long-term emissions in LCA

    DEFF Research Database (Denmark)

    Bakas, Ioannis; Hauschild, Michael Zwicky; Astrup, Thomas Fruergaard

    2015-01-01

    and their differences are highlighted.A suitable dynamic LCI is identified for landfill emissions, which calculates Ni, Zn, Cd and Pb emissions as a function of time, based on assumed developments of the leachate pH. The results of the application of the different impact assessment methods on that LCI differ by up to 8...

  11. Preparing the ground for an operational handling of long-term emissions in LCA

    DEFF Research Database (Denmark)

    Bakas, Ioannis; Hauschild, Michael Zwicky; Astrup, Thomas Fruergaard;

    2015-01-01

    hindering the standardisation of a methodology to account for potential impacts from long-term metal emissions, and to describe the characteristics of a robust framework for an operational impact assessment methodology.In order to demonstrate the issues around potential impacts from long-term emissions...... in LCA and derive a scientific basis for developing an adequate LCA methodology to address these impacts, a two-part review on long-term metal emissions is performed that (a) identifies a suitable time-dependent life cycle inventory (LCI) while underlining the problems in existing emission prediction......-term emissions, it is necessary to (i) represent future potential impacts more accurately by estimating time-dependent characterisation factors (CFs) corresponding to changing environmental conditions, (ii) develop more robust estimations by addressing uncertainty and (iii) refer to actual potential impacts...

  12. New Chicago-Indiana computer network prepared to handle massive data flow

    CERN Multimedia

    2006-01-01

    "The Chicago-Indiana system is ont of five Tier-2 (regional) centers in the United States that will receive data from one of four massive detectors at the Large Hadron Collider at CERN, the European particle physics laboratory in Geneva. When the new instrument begins operating late next year, beams of protons will collide 40 million times a second. When each of those proton beams reaches full intensity, each collision will produce approximately 23 interactions between protons that will create various types of subatomic particles." (1,5 page)

  13. AIDS on Campuses: Concern Goes beyond Health as Officials Prepare to Handle Flood of Questions.

    Science.gov (United States)

    Biemiller, Lawrence

    1985-01-01

    The University of California at Berkeley has established an AIDS-education program to answer questions from worried students, faculty members, and staff employees. Policies are being developed for dealing with a series of complex logistical and philosophical questions that the disease is raising on campus. (MLW)

  14. Zapping Those Zits: Helping Teens Handle Acne.

    Science.gov (United States)

    Martin, Paul

    1992-01-01

    Describes five types of acne and stresses the importance of appropriate treatment. Some dermatologists believe diet is critical in improving acne. Other treatments include the use of drying lotions and soaps, astringents, abrasive cleansers, prescription drugs, face peels, and dermabrasion. (SM)

  15. Entreprenörskap som existentiell handling

    DEFF Research Database (Denmark)

    Kupferberg, Feiwel

    2002-01-01

    In this paper I argut that business economics tends to present an overrationalized view of entrepreurial action. Entrepreneurship is basically an existential type of action, as it includes elements of traditon-breaking activities and emotions related to coping with uncertainty. These existential ...

  16. From Attribute Grammars to Constraint Handling Rules

    NARCIS (Netherlands)

    Serrano Mena, A.; Hage, J.

    2016-01-01

    Attribute grammars provide a framework to de ne compu- tations over trees, by decorating those trees with attributes. Attribute grammars have been successfully applied in many areas, including compiler construction and natural language processing. In this paper we present a translation of attribute

  17. 7 CFR 966.323 - Handling regulation.

    Science.gov (United States)

    2010-01-01

    ... to as pear shaped or paste tomatoes and including but not limited to San Marzano, Red Top, and Roma... greenhouse tomatoes. Specialty packed red ripe tomatoes, yellow meated tomatoes, and single layer and two... tomatoes grown indoors; specialty packed red ripe tomatoes means tomatoes which at the time of...

  18. Extraction, identification, and functional characterization of a bioactive substance from automated compound-handling plastic tips.

    Science.gov (United States)

    Watson, John; Greenough, Emily B; Leet, John E; Ford, Michael J; Drexler, Dieter M; Belcastro, James V; Herbst, John J; Chatterjee, Moneesh; Banks, Martyn

    2009-06-01

    Disposable plastic labware is ubiquitous in contemporary pharmaceutical research laboratories. Plastic labware is routinely used for chemical compound storage and during automated liquid-handling processes that support assay development, high-throughput screening, structure-activity determinations, and liability profiling. However, there is little information available in the literature on the contaminants released from plastic labware upon DMSO exposure and their resultant effects on specific biological assays. The authors report here the extraction, by simple DMSO washing, of a biologically active substance from one particular size of disposable plastic tips used in automated compound handling. The active contaminant was identified as erucamide ((Z)-docos-13-enamide), a long-chain mono-unsaturated fatty acid amide commonly used in plastics manufacturing, by gas chromatography/mass spectroscopy analysis of the DMSO-extracted material. Tip extracts prepared in DMSO, as well as a commercially obtained sample of erucamide, were active in a functional bioassay of a known G-protein-coupled fatty acid receptor. A sample of a different disposable tip product from the same vendor did not release detectable erucamide following solvent extraction, and DMSO extracts prepared from this product were inactive in the receptor functional assay. These results demonstrate that solvent-extractable contaminants from some plastic labware used in the contemporary pharmaceutical research and development (R&D) environment can be introduced into physical and biological assays during routine compound management liquid-handling processes. These contaminants may further possess biological activity and are therefore a potential source of assay-specific confounding artifacts.

  19. [The handling of acute life-threatening choking in geriatric and nursing home patients].

    Science.gov (United States)

    van Poelgeest, A; Melis, R J F; Ritmeijer, C; Olde Rikkert, M G M

    2006-09-01

    It is unknown how often choking occurs in geriatric wards and in nursing homes and what the treatment and outcomes are in regular practice. A questionnaire was sent to Dutch geriatricians (N = 130), nursing home physicians (N = 130), and trainees for these disciplines (N = 215), in order to gain information about the experience, practice and competence of physicians in choking in geriatric and nursing home patients. We also analysed to what extent geriatric and nursing home wards were prepared for accurate handling of choking. The response rate was 30%. More than half of the responders had experienced an episode of food choking at least once in the past five years. The mortality rate in the reported cases was high (30%). The majority of the patients who died of choking had not received the Heimlich-manoeuvre. Physicians who had attended resuscitation training long ago felt as competent to manage a choking episode as physicians that had recently attended resuscitation training. Of all geriatric wards and nursing homes, the majority lacked a guideline on how to handle in acute food choking. Geriatric wards and nursing homes do not seem to be well prepared for acute food choking in several aspects. Despite methodological shortcomings of this study, the results underline the necessity of clarification of the terms used, and development and implementation of guidelines for this important problem.

  20. Mitigating the risk of food handling in the home-delivered meal program.

    Science.gov (United States)

    Namkung, Young; Ismail, Joseph A; Almanza, Barbara A; Nelson, Douglas C

    2007-02-01

    The purpose of this cross-sectional study was to examine the length of time between packing and delivery of home-delivered meals, and the extent of foodborne illness risk to the elderly. Procedures to mitigate that risk were also evaluated. Researchers surveyed 95 drivers from home-delivered meal preparation sites in six states across the United States to determine the average length of time that passed during packing, loading, leaving, and delivery. The efficiency of various risk mitigation methods were evaluated and used to adjust the actual delivery time. Total average delivery time from packing to last delivery was 1.92 hours. This study suggests that the risk associated with the actual 1.92 hours of total delivery time could be mitigated to represent approximately 1.55 hours of effective time with proper packing and holding conditions. This methodology proposes a single measure for evaluating the effectiveness of various handling procedures associated with distributing home-delivered meals, which can be utilized to evaluate overall risk when combined with in-house preparation and client-handling behaviors.