WorldWideScience

Sample records for preliminary performance specification

  1. Preliminary Transportation, Aging and Disposal Canister System Performance Specification

    Energy Technology Data Exchange (ETDEWEB)

    C.A Kouts

    2006-11-22

    This document provides specifications for selected system components of the Transportation, Aging and Disposal (TAD) canister-based system. A list of system specified components and ancillary components are included in Section 1.2. The TAD canister, in conjunction with specialized overpacks will accomplish a number of functions in the management and disposal of spent nuclear fuel. Some of these functions will be accomplished at purchaser sites where commercial spent nuclear fuel (CSNF) is stored, and some will be performed within the Office of Civilian Radioactive Waste Management (OCRWM) transportation and disposal system. This document contains only those requirements unique to applications within Department of Energy's (DOE's) system. DOE recognizes that TAD canisters may have to perform similar functions at purchaser sites. Requirements to meet reactor functions, such as on-site dry storage, handling, and loading for transportation, are expected to be similar to commercially available canister-based systems. This document is intended to be referenced in the license application for the Monitored Geologic Repository (MGR). As such, the requirements cited herein are needed for TAD system use in OCRWM's disposal system. This document contains specifications for the TAD canister, transportation overpack and aging overpack. The remaining components and equipment that are unique to the OCRWM system or for similar purchaser applications will be supplied by others.

  2. Plutonium Immobilization Can Loading Preliminary Specifications

    Energy Technology Data Exchange (ETDEWEB)

    Kriikku, E.

    1998-11-25

    This report discusses the Plutonium Immobilization can loading preliminary equipment specifications and includes a process block diagram, process description, equipment list, preliminary equipment specifications, plan and elevation sketches, and some commercial catalogs. This report identifies loading pucks into cans and backfilling cans with helium as the top priority can loading development areas.

  3. Performance Specifications for Occupational Programs.

    Science.gov (United States)

    Maryland State Dept. of Education, Baltimore. Div. of Career Technology and Adult Learning.

    This document lists and discusses the development of Maryland's performance specifications for occupational programs. The introduction explains the process used to develop performance standards and specifications for 10 career cluster majors that were identified by a task force of educators and employers as high-demand occupational areas in…

  4. Preliminary Anthropometric Specification for Land Vehicles

    Science.gov (United States)

    2012-05-01

    worked for QinetiQ and BAE Systems in the UK. He has provided Human Factors expertise to numerous procurement programs and currently leads the...specification be updated when sufficient data becomes available for the female Army population. 4. It is recommended that the intergenerational change in

  5. Guidance for performing preliminary assessments under CERCLA

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1991-09-01

    EPA headquarters and a national site assessment workgroup produced this guidance for Regional, State, and contractor staff who manage or perform preliminary assessments (PAs). EPA has focused this guidance on the types of sites and site conditions most commonly encountered. The PA approach described in this guidance is generally applicable to a wide variety of sites. However, because of the variability among sites, the amount of information available, and the level of investigative effort required, it is not possible to provide guidance that is equally applicable to all sites. PA investigators should recognize this and be aware that variation from this guidance may be necessary for some sites, particularly for PAs performed at Federal facilities, PAs conducted under EPA`s Environmental Priorities Initiative (EPI), and PAs at sites that have previously been extensively investigated by EPA or others. The purpose of this guidance is to provide instructions for conducting a PA and reporting results. This guidance discusses the information required to evaluate a site and how to obtain it, how to score a site, and reporting requirements. This document also provides guidelines and instruction on PA evaluation, scoring, and the use of standard PA scoresheets. The overall goal of this guidance is to assist PA investigators in conducting high-quality assessments that result in correct site screening or further action recommendations on a nationally consistent basis.

  6. ALMA Nutator Design and Preliminary Performance

    CERN Document Server

    Martin-Cocher, Pierre; Koch, Patrick M; Ni, Chih-Wen; Chen, Wei-Long; Chen, Ming-Tang; Raffin, Philippe; Ong, Chin-Long; Ho, Paul T P; Symmes, Arthur

    2013-01-01

    We report the past two years of collaboration between the di?erent actors on the ALMA nutator. Building on previous developments, the nutator has seen changes in much of the design. A high-modulus carbon ?fiber structure has been added on the back of the mirror in order to transfer the voice coils forces with less deformation, thus reducing delay problems due to flexing. The controller is now an off?-the-shelf National Instrument NI-cRIO, and the ampli?fier a class D servo drive from Advanced Motion Controls, with high peak power able to drive the coils at 300 Volts DC. The stow mechanism has been totally redesigned to improve on the repeatability and precision of the stow position, which is also the reference for the 26 bits Heidenhain encoders. This also improves on the accuracy of the stow position with wind loading. Finally, the software, written largely with National Instrument's LabView, has been developed. We will discuss these changes and the preliminary performances achieved to date. Keywords: ALMA, ...

  7. MATISSE: specifications and expected performances

    CERN Document Server

    Matter, A; Petrov, R G; Berio, P; Robbe-Dubois, S; Lopez, B; Antonelli, P; Allouche, F; Cruzalebes, P; Millour, F; Bazin, G; Bourgès, L

    2016-01-01

    MATISSE (Multi AperTure mid-Infrared SpectroScopic Experiment) is the next generation spectro-interferometer at the European Southern Observatory VLTI operating in the spectral bands L, M and N, and combining four beams from the unit and auxiliary telescopes. MATISSE is now fully integrated at the Observatoire de la C\\^ote d'Azur in Nice (France), and has entered very recently its testing phase in laboratory. This paper summarizes the equations describing the MATISSE signal and the associated sources of noise. The specifications and the expected performances of the instrument are then evaluated taking into account the current characteristics of the instrument and the VLTI infrastructure, including transmission and contrast degradation budgets. In addition, we present the different MATISSE simulation tools that will be made available to the future users.

  8. STACEE-32: Design, performance, and preliminary results

    Science.gov (United States)

    Ong, Rene A.

    2000-06-01

    The Solar Tower Atmospheric Cherenkov Effect Experiment (STACEE) is designed to detect astrophysical sources of γ-rays at energies between 25 and 500 GeV. STACEE uses large solar mirrors (heliostats) to collect the atmospheric Cherenkov radiation produced in γ-ray air showers. The use of a large mirror collection area will allow STACEE to probe γ-ray sources at energies above the reach of the Compton Gamma Ray Observatory (CGRO), but below the reach of conventional Cherenkov telescopes. During the 1998-99 observing season, a portion of STACEE using 32 heliostats was installed at the National Solar Thermal Test Facility (NSTTF) of Sandia National Laboratories (Albuquerque, NM). This initial configuration (STACEE-32) observed a number of astronomical sources, including the Crab and several active galactic nuclei (AGN). Here we report on these observations. We highlight the experimental configuration and the preliminary results from the Crab data. The full STACEE experiment using 64 heliostats will be commissioned in 2000. .

  9. CONTRACT DOCUMENTS AND PERFORMANCE SPECIFICATIONS.

    Science.gov (United States)

    First California Commission on School Construction Systems, Palo Alto.

    A SET OF EDUCATIONAL SPECIFICATION DRAFTED BY THE FIRST CALIFORNIA COMMISSION ON SCHOOL CONSTRUCTION SYSTEMS GIVES INFORMATION ON BIDDING PROCEDURES, A DESCRIPTION OF THE CURRENT CONSTRUCTION PROGRAM, PROCEDURES FOR SUBMITTING A PROPOSAL, DATA AND CONDITIONS RELATED TO THE DEVELOPMENT PHASE OF THE PROJECT, COMPONENT CONTRACTS, AND GENERAL…

  10. Biofeedback and dance performance: a preliminary investigation.

    Science.gov (United States)

    Raymond, Joshua; Sajid, Imran; Parkinson, Lesley A; Gruzelier, John H

    2005-03-01

    Alpha-theta neurofeedback has been shown to produce professionally significant performance improvements in music students. The present study aimed to extend this work to a different performing art and compare alpha-theta neurofeedback with another form of biofeedback: heart rate variability (HRV) biofeedback. Twenty-four ballroom and Latin dancers were randomly allocated to three groups, one receiving neurofeedback, one HRV biofeedback and one no intervention. Dance was assessed before and after training. Performance improvements were found in the biofeedback groups but not in the control group. Neurofeedback and HRV biofeedback benefited performance in different ways. A replication with larger sample sizes is required.

  11. SITE-94. Site specific base data for the performance assessment

    Energy Technology Data Exchange (ETDEWEB)

    Geier, J. [ed.] [Clearwater Hardrock Consulting, Monmouth, OR (United States); Tiren, S. [Geosigma AB, Uppsala (Sweden); Dverstorp, B. [Swedish Nuclear Power Inspectorate, Stockholm (Sweden); Glynn, P. [U.S. Geological Survey, Reston, VA (United States)

    1996-06-01

    This report documents the site specific base data that were available, and the utilization of these data within SITE-94. A brief summary is given of SKB`s preliminary site investigations for the Aespoe Hard Rock Laboratory (HRL), which were the main source of site-specific data for SITE-94, and an overview is given of the field methods and instrumentation for the preliminary investigations. A compilation is given of comments concerning the availability and quality of the data for Aespoe, and specific recommendations are given for future site investigations. It was found that the HRL pre-investigations produced a large quantity of data which were, for the most part, of sufficient quality to be valuable for a performance assessment. However, some problems were encountered regarding documentation, procedural consistency, positional information, and storage of the data from the measurements. 77 refs, 4 tabs.

  12. Advanced stellar compass - Onboard autonomous orbit determination, preliminary performance

    DEFF Research Database (Denmark)

    Betto, Maurizio; Jørgensen, John Leif; Jørgensen, Peter Siegbjørn

    2004-01-01

    of this instrument, the authors have devised a method to determine the orbit of a spacecraft autonomously, onboard, and without a priori knowledge of any kind. The solution is robust and fast. This paper presents the preliminary performance obtained during the ground testing in August 2002 at the Mauna Kea...... be implemented into an ASC without degrading the attitude measurements; and (4) to identify the areas of development and consolidation. The results obtained are very encouraging....

  13. Performance management in the Slovak higher education system: preliminary evaluation

    Directory of Open Access Journals (Sweden)

    Juraj Nemec

    2007-10-01

    Full Text Available The aim of our paper is a preliminary evaluation of the introduction of performance management and performance financing arrangements in the Slovak higher education system – accreditation and formula based performance financing. This evaluation will be mainly based on the assessment of short-term impacts of the above mentioned instruments and is expected to invite further professional discussion. We feel that the data and brief analysis included are sufficient enough to show that the Slovak system represents a typical example of the potential of performance management and performance financing being significantly limited, if not destroyed. Not only because of improperly defined indicators, which are too much input and quantity orientated, but very much also due to a lack of resources (the ratio of public expenditures for higher education to the GDP in Slovakia is significantly below EU average, as well as the politicization of the system.

  14. A specification language for organisational performance indicators

    NARCIS (Netherlands)

    Popova, Viara; Treur, Jan

    2007-01-01

    A specification language for performance indicators and their relations and requirements is presented and illustrated for a case study in logistics. The language can be used in different forms, varying from informal, semiformal, graphical to formal. A software environment has been developed that s

  15. Performance specifications for proton medical facility

    Energy Technology Data Exchange (ETDEWEB)

    Chu, W.T.; Staples, J.W.; Ludewigt, B.A.; Renner, T.R.; Singh, R.P.; Nyman, M.A.; Collier, J.M.; Daftari, I.K.; Petti, P.L.; Alonso, J.R. [Lawrence Berkeley Lab., CA (United States); Kubo, H.; Verhey, L.J. [University of California Davis Medical Center, Sacramento, CA (United States). Cancer Center]|[California Univ., San Francisco, CA (United States). School of Medicine; Castro, J.R. [Lawrence Berkeley Lab., CA (United States)]|[University of California Davis Medical Center, Sacramento, CA (United States). Cancer Center]|[California Univ., San Francisco, CA (United States). School of Medicine

    1993-03-01

    Performance specifications of technical components of a modern proton radiotherapy facility are presented. The technical items specified include: the accelerator; the beam transport system including rotating gantry; the treatment beamline systems including beam scattering, beam scanning, and dosimetric instrumentation; and an integrated treatment and accelerator control system. Also included are treatment ancillary facilities such as diagnostic tools, patient positioning and alignment devices, and treatment planning systems. The facility specified will accommodate beam scanning enabling the three-dimensional conformal therapy deliver .

  16. Voltage-Controlled Sapphire Oscillator: Design, Development, and Preliminary Performance

    Science.gov (United States)

    Wang, R. T.; Dick, G. J.; Tjoelker, R. L.

    2007-08-01

    We present the design for a new short-term frequency standard, the voltage-controlled sapphire oscillator, as a practical and lower-cost alternative to a cryogenic sapphire oscillator operating at liquid helium temperatures. Performance goals are a frequency stability of 1 x 10^-14 (1 second equal to or less than tau equal to or less than 100 seconds), more than 2 years of continuous operation, and practical operability. Key elements include the sapphire resonator, low-power and long-life cryocooler, frequency compensation method, and cryo-Pound design. We report the design verification, experimental results, and test results of the cryocooler environmental sensitivity, as well as a preliminary stability measurement.

  17. Advanced stellar compass onboard autonomous orbit determination, preliminary performance.

    Science.gov (United States)

    Betto, Maurizio; Jørgensen, John L; Jørgensen, Peter S; Denver, Troelz

    2004-05-01

    Deep space exploration is in the agenda of the major space agencies worldwide; certainly the European Space Agency (SMART Program) and the American NASA (New Millennium Program) have set up programs to allow the development and the demonstration of technologies that can reduce the risks and the cost of deep space missions. From past experience, it appears that navigation is the Achilles heel of deep space missions. Performed on ground, this imposes considerable constraints on the entire system and limits operations. This makes it is very expensive to execute, especially when the mission lasts several years and, furthermore, it is not failure tolerant. Nevertheless, to date, ground navigation has been the only viable solution. The technology breakthrough of advanced star trackers, like the advanced stellar compass (ASC), might change this situation. Indeed, exploiting the capabilities of this instrument, the authors have devised a method to determine the orbit of a spacecraft autonomously, onboard, and without a priori knowledge of any kind. The solution is robust and fast. This paper presents the preliminary performance obtained during the ground testing in August 2002 at the Mauna Kea Observatories. The main goals were: (1) to assess the robustness of the method in solving autonomously, onboard, the position lost-in-space problem; (2) to assess the preliminary accuracy achievable with a single planet and a single observation; (3) to verify the autonomous navigation (AutoNav) module could be implemented into an ASC without degrading the attitude measurements; and (4) to identify the areas of development and consolidation. The results obtained are very encouraging.

  18. Preliminary design of the Carrisa Plains solar central receiver power plant. Volume II. Plant specifications

    Energy Technology Data Exchange (ETDEWEB)

    Price, R. E.

    1983-12-31

    The specifications and design criteria for all plant systems and subsystems used in developing the preliminary design of Carrisa Plains 30-MWe Solar Plant are contained in this volume. The specifications have been organized according to plant systems and levels. The levels are arranged in tiers. Starting at the top tier and proceeding down, the specification levels are the plant, system, subsystem, components, and fabrication. A tab number, listed in the index, has been assigned each document to facilitate document location.

  19. Noradrenaline blockade specifically enhances metacognitive performance

    Science.gov (United States)

    Hauser, Tobias U; Allen, Micah; Purg, Nina; Moutoussis, Michael; Rees, Geraint; Dolan, Raymond J

    2017-01-01

    Impairments in metacognition, the ability to accurately report one’s performance, are common in patients with psychiatric disorders, where a putative neuromodulatory dysregulation provides the rationale for pharmacological interventions. Previously, we have shown how unexpected arousal modulates metacognition (Allen et al., 2016). Here, we report a double-blind, placebo-controlled, study that examined specific effects of noradrenaline and dopamine on both metacognition and perceptual decision making. Signal theoretic analysis of a global motion discrimination task with adaptive performance staircasing revealed that noradrenergic blockade (40 mg propranolol) significantly increased metacognitive performance (type-II area under the curve, AUROC2), but had no impact on perceptual decision making performance. Blockade of dopamine D2/3 receptors (400 mg amisulpride) had no effect on either metacognition or perceptual decision making. Our study is the first to show a pharmacological enhancement of metacognitive performance, in the absence of any effect on perceptual decision making. This enhancement points to a regulatory role for noradrenergic neurotransmission in perceptual metacognition. DOI: http://dx.doi.org/10.7554/eLife.24901.001 PMID:28489001

  20. Preliminary Analysis of Remote Monitoring & Robotic Concepts for Performance Confirmation

    Energy Technology Data Exchange (ETDEWEB)

    D.A. McAffee

    1997-02-18

    ) Identify and discuss the main Performance Confirmation monitoring needs and requirements during the post-emplacement preclosure period. This includes radiological, non-radiological, host rock, and infrastructure performance monitoring needs. It also includes monitoring for possible off-normal events. (Presented in Section 7.3). (3) Identify general approaches and methods for obtaining performance information from within the emplacement drifts for Performance Confirmation. (Presented in Section 7.4) (4)Review and discuss available technologies and design strategies that may permit the use of remotely operated systems within the hostile thermal and radiation environment expected within the emplacement drifts. (Presented in Section 7.5). (5) Based on Performance Confirmation monitoring needs and available technologies, identify potential application areas for remote systems and robotics for post-emplacement preclosure Performance Confirmation activities (Presented in Section 7.6). (6) Develop preliminary remote monitoring and robotic concepts for post-emplacement, preclosure Performance Confirmation activities. (Presented in Section 7.7) This analysis is being performed very early in the systems engineering cycle, even as issues related to the Performance Confirmation program planning phase are being formulated and while the associated needs, constraints and objectives are yet to be fully determined and defined. This analysis is part of an issue formulation effort and is primarily concerned with identification and description of key issues related to remotely monitoring repository performance for Performance Confirmation. One of the purposes of this analysis is to provide an early investigation of potential design challenges that may have a high impact on future design concepts. This analysis can be used to guide future concept development and help access what is feasible and achievable by application of remote systems technology. Future design and systems engineering

  1. High-performance liquid chromatographic assay for benzocaine and p-aminobenzoic acid including preliminary stability data.

    Science.gov (United States)

    Narang, P K; Bird, G; Crouthamel, W G

    1980-12-01

    A high-performance liquid chromatographic assay was developed that separates and quantitates benzocaine and its primary degradation product, p-aminobenzoic acid. This method is rapid, sensitive, and specific. Preliminary stability data obtained with this method demonstrate its utility for this purpose.

  2. Position-specific behaviors and their impact on crew performance: Implications for training

    Science.gov (United States)

    Law, J. Randolph

    1993-01-01

    The present study was motivated by results from a preliminary report documenting the impact of specific crewmembers on overall crew performance (Wilhelm & Law, 1992), and a cross-airline cross-fleet project investigating human factors behaviors of commercial aviation flightcrews (Helmreich, Butler, Whilhelm, & Lofaro, 1992). The purpose of the current investigation is to study how position-specific behaviors impact flightcrew performance, and how these position-specific behaviors differ between two airlines and two flying environments. Implications for training will also be addressed.

  3. Preliminary performance assessment for the Waste Isolation Pilot Plant, December 1992. Volume 2, Technical basis

    Energy Technology Data Exchange (ETDEWEB)

    1992-12-01

    Before disposing of transuranic radioactive waste in the Waste Isolation Pilot Plant (WIPP), the United States Department of Energy (DOE) must evaluate compliance with applicable long-term regulations of the United States Environmental Protection Agency (EPA). Sandia National Laboratories is conducting iterative performance assessments (PAs) of the WIPP for the DOE to provide interim guidance while preparing for a final compliance evaluation. This volume, Volume 2, contains the technical basis for the 1992 PA. Specifically, it describes the conceptual basis for consequence modeling and the PA methodology, including the selection of scenarios for analysis, the determination of scenario probabilities, and the estimation of scenario consequences using a Monte Carlo technique and a linked system of computational models. Additional information about the 1992 PA is provided in other volumes. Volume I contains an overview of WIPP PA and results of a preliminary comparison with the long-term requirements of the EPA`s Environmental Protection Standards for Management and Disposal of Spent Nuclear Fuel, High-Level and Transuranic Radioactive Wastes (40 CFR 191, Subpart B). Volume 3 contains the reference data base and values for input parameters used in consequence and probability modeling. Volume 4 contains uncertainty and sensitivity analyses related to the preliminary comparison with 40 CFR 191B. Volume 5 contains uncertainty and sensitivity analyses of gas and brine migration for undisturbed performance. Finally, guidance derived from the entire 1992 PA is presented in Volume 6.

  4. PORFLOW MODELING FOR A PRELIMINARY ASSESSMENT OF THE PERFORMANCE OF NEW SALTSTONE DISPOSAL UNIT DESIGNS

    Energy Technology Data Exchange (ETDEWEB)

    Smith, F.

    2012-08-06

    At the request of Savannah River Remediation (SRR), SRNL has analyzed the expected performance obtained from using seven 32 million gallon Saltstone Disposal Units (SDUs) in the Z-Area Saltstone Disposal Facility (SDF) to store future saltstone grout. The analysis was based on preliminary SDU final design specifications. The analysis used PORFLOW modeling to calculate the release of 20 radionuclides from an SDU and transport of the radionuclides and daughters through the vadose zone. Results from this vadose zone analysis were combined with previously calculated releases from existing saltstone vaults and FDCs and a second PORFLOW model run to calculate aquifer transport to assessment points located along a boundary 100 m from the nearest edge of the SDF sources. Peak concentrations within 12 sectors spaced along the 100 m boundary were determined over a period of evaluation extending 20,000 years after SDF closure cap placement. These peak concentrations were provided to SRR to use as input for dose calculations.

  5. Dynamic Performance Tuning Supported by Program Specification

    Directory of Open Access Journals (Sweden)

    Eduardo César

    2002-01-01

    Full Text Available Performance analysis and tuning of parallel/distributed applications are very difficult tasks for non-expert programmers. It is necessary to provide tools that automatically carry out these tasks. These can be static tools that carry out the analysis on a post-mortem phase or can tune the application on the fly. Both kind of tools have their target applications. Static automatic analysis tools are suitable for stable application while dynamic tuning tools are more appropriate to applications with dynamic behaviour. In this paper, we describe KappaPi as an example of a static automatic performance analysis tool, and also a general environment based on parallel patterns for developing and dynamically tuning parallel/distributed applications.

  6. Specific Mindfulness Skills Differentially Predict Creative Performance.

    Science.gov (United States)

    Baas, Matthijs; Nevicka, Barbara; Ten Velden, Femke S

    2014-05-23

    Past work has linked mindfulness to improved emotion regulation, interpersonal skills, and basic cognitive abilities, but is unclear about the relation between mindfulness and creativity. Studies examining effects of mindfulness on factors pertinent to creativity suggest a uniform and positive relation, whereas work on specific mindfulness skills suggests that mindfulness skills may differentially predict creativity. To test whether the relation between mindfulness and creativity is positive and uniform (the uniform hypothesis) or differentially depends on particular components of mindfulness (the differential hypothesis), we conducted four studies in which mindfulness skills were measured, extensively trained, or manipulated with a short, incidental meditation session. Results supported a differential relation between mindfulness and creativity: Only the ability to observe and attend to various stimuli consistently and positively predicted creativity. Results regarding other mindfulness skills were less consistent. Implications for theory and practice are discussed.

  7. Analysis of Design Basis Events in a Preliminary Specific Design of PGSFR

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Kwi Lim; Ha, Kwi Seok [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2014-05-15

    KAERI(Korea Atomic Energy Research Institute) has been developing a preliminary specific design of the PGSFR(Prototype Gen-IV Sodium-cooled Fast Reactor), which is a pool type sodium cooled fast reactor with a thermal power of 392.2 MW. Many alterations were made on a preliminary specific design of the PGSFR compared with a conceptual design: a heat removal capability of the DHRS was decreased, the DHXs were submerged in a cold pool, a pressure drop through the core was increased, and a shape of a redon was changed to a peanut type, etc. For identification of safety characteristics including the design changes, 5 DBE's(Design Bases Events) were analyzed using MARS-LMR code. The representative DBE's are TOP(Transient of Over Power), LOF(Loss Of Flow), LOHS(Loss Of Heat Sink), Reactor Vessel Leak and Pipe Break accidents. The representative DBE's were analyzed using the MARS-LMR code. As a result, it was identified that the PGSFR were appropriately tripped by the RPS(Reactor Protection System) and cooled by the DHRS. But a high cladding temperature was estimated in a pipe break accident. Therefore, integrity of the structure should be evaluated in the further study.

  8. Reliability and Factorial Validity of Non-Specific and Tennis-Specific Pre-Planned Agility Tests; Preliminary Analysis

    Science.gov (United States)

    Sekulic, Damir; Uljevic, Ognjen; Peric, Mia; Spasic, Miodrag; Kondric, Miran

    2017-01-01

    Abstract Agility is an important quality in tennis, yet there is an evident lack of studies focussing on the applicability of tennis-specific agility performances and comparing them to equivalent non-specific agility performances. The aim of this study was to evaluate the reliability and factorial validity of three tests of pre-planned agility, performed in specific (with a tennis racquet) and non-specific (without a tennis racquet) conditions. The sample consisted of 33 tennis players (13 males and 20 females; age: 18.3 ± 1.1 years and 18.6 ± 1.3 years; body height: 185.4 ± 51 cm and 169.3 ± 4.2 cm, 74.0 ± 4.4 kg and 61.2 ± 3.1 kg, respectively). The variables comprised three agility tests: a 20-yard test, a T-test and the Illinois test, all performed in both specific and non-specific conditions. Between-subject and within-subject reliability were found to be high (Cronbach Alpha: 0.93 to 0.98; Coefficient of Variation: 3 to 8%), with better within-subject reliability and stability of the measurement for specific tests. Pearson’s product moment correlations between the non-specific and specific agility performances were high (r ≥0.84), while factor analysis extracted only one significant latent dimension on the basis of the Guttman-Kaiser criterion. The results of the 20-yard test were better when the test was conducted in the specific conditions (t-test = 2.66; p test, superior results were recorded in the non-specific conditions (t-test = 2.96; p test duration (about 20 s) and non-specific locomotion forms such as rotational movements. Considering the findings of the present study, when testing tennis-specific pre-planned agility, we suggest using tests of short duration (less than 10 s) and sport-specific types of locomotion. PMID:28210343

  9. Performance characteristics of DRI, CEDIA, and REMEDi systems for preliminary tests of amphetamines and opiates in human urine.

    Science.gov (United States)

    Huang, Min-Kun; Dai, Yu-Shan; Lee, Choung-Huei; Liu, Chiareiy; Tsay, Wen-Ing; Li, Jih-Heng

    2006-01-01

    Arrestee urine specimens (930) were tested with DRI, CEDIA, and REMEDi; those that tested positive for amphetamines and opiates (616 and 414, respectively) were then confirmed by gas chromatography-mass spectrometry. The performance characteristics of these three preliminary systems were evaluated using the following commonly used parameters: true positive, true negative, false positive, and false negative. The sensitivity, specificity, and efficiency of these methods were also calculated. Data derived from this study indicated DRI and CEDIA adapted by this study generated acceptable preliminary test results for amphetamine/methamphetamine and morphine/codeine, but not for MDA/MDMA and REMEDi has lower sensitivity than DRI and CEDIA, but with better specificity and efficiency, supporting its use under emergency room settings where drug concentrations in overdose cases are expectedly at high levels.

  10. Design and preliminary validation of a tool for the simulation of train braking performance

    Institute of Scientific and Technical Information of China (English)

    Luca Pugi; Monica Malvezzi; Susanna Papini; Gregorio Vettori

    2013-01-01

    Train braking performance is important for the safety and reliability of railway systems. The availability of a tool that allows evaluating such performance on the basis of the main train features can be useful for train system designers to choose proper dimensions for and optimize train’s subsystems. This paper presents a modular tool for the prediction of train braking performance, with a par-ticular attention to the accurate prediction of stopping distances. The tool takes into account different loading and operating conditions, in order to verify the safety require-ments prescribed by European technical specifications for interoperability of high-speed trains and the corresponding EN regulations. The numerical results given by the tool were verified and validated by comparison with experi-mental data, considering as benchmark case an Ansaldo EMU V250 train-a European high-speed train-currently developed for Belgium and Netherlands high-speed lines, on which technical information and experimental data directly recorded during the preliminary tests were avail-able. An accurate identification of the influence of the braking pad friction factor on braking performances allowed obtaining reliable results.

  11. Preliminary performance report of the RHUM-RUM OBS network

    Science.gov (United States)

    Stähler, Simon C.; Crawford, Wayne; Barruol, Guilhem; Sigloch, Karin; Mechita, Schmidt-Aursch

    2015-04-01

    RHUM-RUM is a German-French seismological experiment based on the seafloor surrounding the hotspot of La Réunion, western Indian Ocean. Its primary objective is to clarify the presence or absence of a mantle plume beneath the Reunion hotspot. RHUM-RUM's central component is a one-year deployment (Oct 2012 - Nov 2013) of 57 broadband ocean-bottom seismometers (OBS) and hydrophones on an area of 2000x2000 km2 surrounding the hotspot. The OBS pool contained 48 instruments from the German DEPAS pool and 9 French stations from INSU. All OBS have been successfully recovered. Preliminary analysis of the seismometer recordings show large differences in long-period (>10s) noise levels between the German and the French OBS. These differences are strongest on the horizontal components and can be probably explained by dynamic tilt of the instrument itself. The noise level of the German instruments is >20dB higher in this period range compared to the French ones. A reason could be that for the German OBS, the seismometer is integrated into the OBS frame and therefore affected by its movement due to currents. The high noise level on the horizontal components will have to be considered in future experiment design, when using this instrument type for three-component waveform tomography.

  12. New technologies and new performances of the JCMT radio-telescope: a preliminary design study

    Science.gov (United States)

    Mian, S.; De Lorenzi, S.; Ghedin, L.; Rampini, F.; Marchiori, G.; Craig, S.

    2012-09-01

    With a diameter of 15m the James Clerk Maxwell Telescope (JCMT) is the largest astronomical telescope in the world designed specifically to operate in the submillimeter wavelength region of the spectrum. It is situated close to the summit of Mauna Kea, Hawaii, at an altitude of 4092m. Its primary reflector currently consists of a steel geodesic supporting structure and pressed aluminium panels on a passive mount. The major issues of the present reflector are its thermal stability and its panels deterioration. A preliminary design study for the replacement of the JCMT antenna dish is here presented. The requested shape error for the new reflector is antenna performance in terms of both stiffness and thermal stability, so that the required surface accuracy of the primary can be achieved even by adopting a passive panels system. Moreover thanks to CFRP, a considerable weight reduction of the elevation structure can be attained. The performance of the proposed solution for the JCMT antenna has been investigated through FE analyses and the assessed deformation of the structure under different loading cases has been taken into account for subsequent error budgeting. Results show that the proposed solution is in line with the requested performance. With this new backing structure, the JCMT would have the largest CFRP reflector ever built.

  13. Specific phobia: a review of DSM-IV specific phobia and preliminary recommendations for DSM-V.

    Science.gov (United States)

    LeBeau, Richard T; Glenn, Daniel; Liao, Betty; Wittchen, Hans-Ulrich; Beesdo-Baum, Katja; Ollendick, Thomas; Craske, Michelle G

    2010-02-01

    The present review was conducted in order to evaluate the current diagnostic criteria for specific phobia (SP) in light of the empirical evidence gathered since DSM-IV and to propose changes to DSM-V where change is clearly and reliably indicated by the evidence. In response to questions put forth by the DSM-V Anxiety, OC Spectrum, Posttraumatic, and Dissociative Disorder Work Group, four primary areas were determined for this review: the accuracy and utility of the current SP type classification system, the validity of test anxiety as a type of SP, the boundary between agoraphobia and SP, and the reliability and utility of the diagnostic criteria for SP. Developmental issues are addressed within each area. Literature reviews examining academic findings published between 1994 and 2009 were carried out and the results are included herein. The review presents a number of options and preliminary recommendations to be considered for DSM-V. All of these recommendations should be considered tentative as they await the field trials and expert consensus necessary prior to their inclusion in the DSM-V. The present review also reveals a great need for future research in the area of SP and directions for such research is provided.

  14. Ocean thermal energy conversion (OTEC) power system development (PSD) II. Preliminary design report. Appendix I: specifications and drawings

    Energy Technology Data Exchange (ETDEWEB)

    Pearson, R.O.

    1979-08-10

    This volume contains the specifications and drawings prepared in support of the preliminary design of a 10MWe OTEC power system using enhanced plate type heat exchangers. Included are: (1) the specification tree; (2) system specification; (3) 10 MWe heat exchangers; (4) nitrogen storage, conditioning and supply subsystem specification; (5) ammonia storage, conditioning and supply specification; (6) electrical power distribution and control subsystem specification; (7) equipment valves, instruments and live lists and specifications; (8) drawing tree; (9) drawing package; and (10) 0.2 MWe test articles procurement specifications. (WHK)

  15. Performance analysis tool (PATO): Development and preliminary validation

    National Research Council Canada - National Science Library

    Fernando Martins; Filipe Clemente; Frutuoso Silva

    2017-01-01

    .... The Performance Analysis Tool (PATO) software was built with the aim to quickly codify relationships between players and built the adjacency matrices that can be used to test the network measures...

  16. Preliminary Specification of a Silicon Strip Readout Chip for the LHCb Upgrade

    CERN Document Server

    Parkes, Christopher; Idzik, Marek; Van Beuzekom, Martinus; Wyllie, Kenneth; Buytaert, Jan; Collins, Paula; Artuso, Marina; Smith, Anthony Nigel; Eklund, Lars; Dijkstra, Hans; Ferro-Luzzi, Massimiliano

    2012-01-01

    This note documents discussions held between the autumn of 2011 and summer 2012 on an outline specification for the readout chip for silicon strip detectors for the LHCb upgrade. Specifications are set for the external layout, analogue front-end and digitisation performance, and initial comments are included on the digital processing stages.

  17. Selected Teacher Performance Specifications Generally Applicable to Teacher Education Curricula.

    Science.gov (United States)

    Johnson, Charles E.; Shearron, Gilbert F.

    This bulletin contains selected lists of teacher performance specifications regarded as generally applicable to teacher education curriculum for undergraduates. ("Performance specifications" are statements which describe particular competencies or competency requirements that a teacher should possess in order to operate at optimum effectiveness in…

  18. 40 CFR 1065.205 - Performance specifications for measurement instruments.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 32 2010-07-01 2010-07-01 false Performance specifications for... (CONTINUED) AIR POLLUTION CONTROLS ENGINE-TESTING PROCEDURES Measurement Instruments § 1065.205 Performance specifications for measurement instruments. Your test system as a whole must meet all the applicable...

  19. The lunar gravity mission MAGIA: preliminary design and performances

    Science.gov (United States)

    Fermi, Marco; Gregnanin, Marco; Mazzolena, Marco; Chersich, Massimiliano; Reguzzoni, Mirko; Sansò, Fernando

    2011-10-01

    The importance of an accurate model of the Moon gravity field has been assessed for future navigation missions orbiting and/or landing on the Moon, in order to use our natural satellite as an intermediate base for next solar system observations and exploration as well as for lunar resources mapping and exploitation. One of the main scientific goals of MAGIA mission, whose Phase A study has been recently funded by the Italian Space Agency (ASI), is the mapping of lunar gravitational anomalies, and in particular those on the hidden side of the Moon, with an accuracy of 1 mGal RMS at lunar surface in the global solution of the gravitational field up to degree and order 80. MAGIA gravimetric experiment is performed into two phases: the first one, along which the main satellite shall perform remote sensing of the Moon surface, foresees the use of Precise Orbit Determination (POD) data available from ground tracking of the main satellite for the determination of the long wavelength components of gravitational field. Improvement in the accuracy of POD results are expected by the use of ISA, the Italian accelerometer on board the main satellite. Additional gravitational data from recent missions, like Kaguya/Selene, could be used in order to enhance the accuracy of such results. In the second phase the medium/short wavelength components of gravitational field shall be obtained through a low-to-low (GRACE-like) Satellite-to-Satellite Tracking (SST) experiment. POD data shall be acquired during the whole mission duration, while the SST data shall be available after the remote sensing phase, when the sub-satellite shall be released from the main one and both satellites shall be left in a free-fall dynamics in the gravity field of the Moon. SST range-rate data between the two satellites shall be measured through an inter-satellite link with accuracy compliant with current state of art space qualified technology. SST processing and gravitational anomalies retrieval shall

  20. The Effect of Specific Sling Exercises on the Functional Movement Screen Score in Adolescent Volleyball Players: A Preliminary Study

    Directory of Open Access Journals (Sweden)

    Linek Paweł

    2016-12-01

    Full Text Available The existing data indicate that the result of the Functional Movement Screen (FMS test influences the likelihood of subsequent injury in professional athletes. Therefore, exercises increasing test scores of the FMS may be useful at various stages of sports activity. This study evaluated the effects of the NEURAC sling exercises method on the FMS test score in teenage volleyball players. The study was conducted on 15 volleyball players aged 14 years. The FMS test was performed three times interspersed with a two-month interval. Between the first and the second assessment, neither additional treatment nor training was applied, while between the second and the third assessment, the participants performed stabilisation exercises based on the NEURAC method. Training was carried out twice a week, for eight weeks. The analysis showed that between the first and the second measurement, no significant differences occurred. The use of specific sling exercises caused a significant improvement in FMS results (p ≤ 0.01 between the first and the third, as well as the second and the third measurement. The applied stabilisation exercises based on the NEURAC method positively influenced the FMS test result in male subjects practicing volleyball. Performance of such exercises also resulted in more than 90% of the subjects having a total FMS test score ≥ 17, which may be important in the prevention of injuries. The preliminary results indicate that this type of exercise should be included in a teenage volleyball training routine.

  1. The Effect of Specific Sling Exercises on the Functional Movement Screen Score in Adolescent Volleyball Players: A Preliminary Study

    Science.gov (United States)

    Saulicz, Edward; Myśliwiec, Andrzej; Wójtowicz, Monika; Wolny, Tomasz

    2016-01-01

    Abstract The existing data indicate that the result of the Functional Movement Screen (FMS) test influences the likelihood of subsequent injury in professional athletes. Therefore, exercises increasing test scores of the FMS may be useful at various stages of sports activity. This study evaluated the effects of the NEURAC sling exercises method on the FMS test score in teenage volleyball players. The study was conducted on 15 volleyball players aged 14 years. The FMS test was performed three times interspersed with a two-month interval. Between the first and the second assessment, neither additional treatment nor training was applied, while between the second and the third assessment, the participants performed stabilisation exercises based on the NEURAC method. Training was carried out twice a week, for eight weeks. The analysis showed that between the first and the second measurement, no significant differences occurred. The use of specific sling exercises caused a significant improvement in FMS results (p ≤ 0.01) between the first and the third, as well as the second and the third measurement. The applied stabilisation exercises based on the NEURAC method positively influenced the FMS test result in male subjects practicing volleyball. Performance of such exercises also resulted in more than 90% of the subjects having a total FMS test score ≥ 17, which may be important in the prevention of injuries. The preliminary results indicate that this type of exercise should be included in a teenage volleyball training routine. PMID:28031760

  2. Hydronic radiant cooling: Overview and preliminary performance assessment

    Energy Technology Data Exchange (ETDEWEB)

    Feustel, H.E.

    1993-05-01

    A significant amount of electrical energy used to cool non-residential buildings is drawn by the fans used to transport the cool air through the thermal distribution system. Hydronic systems reduce the amount of air transported through the building by separating ventilation and thermal conditioning. Due to the physical properties of water, hydronic distribution systems can transport a given amount of thermal energy using less than 5% of the otherwise necessary fan energy. This savings alone significantly reduces the energy consumption and especially the peak power requirement This survey clearly shows advantages for radiant cooling in combination with hydronic thermal distribution systems in comparison with the All-Air Systems commonly used in California. The report describes a literature survey on the system`s development, thermal comfort issues, and cooling performance. The cooling power potential and the cooling power requirement are investigated for several California climates. Peak-power requirement is compared for hydronic radiant cooling and conventional All-Air-Systems.

  3. Hydronic radiant cooling: Overview and preliminary performance assessment

    Energy Technology Data Exchange (ETDEWEB)

    Feustel, H.E.

    1993-05-01

    A significant amount of electrical energy used to cool non-residential buildings is drawn by the fans used to transport the cool air through the thermal distribution system. Hydronic systems reduce the amount of air transported through the building by separating ventilation and thermal conditioning. Due to the physical properties of water, hydronic distribution systems can transport a given amount of thermal energy using less than 5% of the otherwise necessary fan energy. This savings alone significantly reduces the energy consumption and especially the peak power requirement This survey clearly shows advantages for radiant cooling in combination with hydronic thermal distribution systems in comparison with the All-Air Systems commonly used in California. The report describes a literature survey on the system's development, thermal comfort issues, and cooling performance. The cooling power potential and the cooling power requirement are investigated for several California climates. Peak-power requirement is compared for hydronic radiant cooling and conventional All-Air-Systems.

  4. The Thermo Scientific HELIX-SFT noble gas mass spectrometer: (preliminary) performance for 40Ar/39Ar geochronology

    Science.gov (United States)

    Barfod, D. N.; Mark, D. F.; Morgan, L. E.; Tomkinson, T.; Stuart, F.; Imlach, J.; Hamilton, D.

    2011-12-01

    The Thermo Scientific HELIX-platform Split Flight Tube (HELIX-SFT) noble gas mass spectrometer is specifically designed for simultaneous collection of helium isotopes. The high mass spur houses a switchable 1011 - 1012 Ω resistor Faraday cup and the low mass spur a digital pulse-counting secondary electron multiplier (SEM). We have acquired the HELIX-SFT with the specific intention to measure argon isotopes for 40Ar/39Ar geochronology. This contribution will discuss preliminary performance (resolution, reproducibility, precision etc.) with respect to measuring argon isotope ratios for 40Ar/39Ar dating of geological materials. We anticipate the greatest impact for 40Ar/39Ar dating will be increased accuracy and precision, especially as we approach the techniques younger limit. Working with Thermo Scientific we have subtly modified the source, alpha and collector slits of the HELIX-SFT mass spectrometer to improve its resolution for resolving isobaric interferences at masses 36 to 40. The enhanced performance will allow for accurate and precise measurement of argon isotopes. Preliminary investigations show that we can obtain a valley resolution of >700 and >1300 (compared to standard HELIX-SFT specifications of >400 and >700) for the high and low mass spurs, respectively. The improvement allows for full resolution of hydrocarbons (C3+) at masses 37 - 40 and almost full resolution at mass 36. The HELIX-SFT will collect data in dual collection mode with 40Ar+ ion beams measured using the switchable 1011 - 1012 Ω resistor Faraday cup and 39Ar through 36Ar measured using the SEM. The HELIX-SFT requires Faraday-SEM inter-calibration but negates the necessity to inter-calibrate multiple electron multipliers. We will further present preliminary data from the dating of mineral standards: Alder Creek sanidine, Fish Canyon sanidine and Mount Dromedary biotite (GA1550).

  5. Crystallization and preliminary X-ray crystallographic analysis of yeast NAD{sup +}-specific isocitrate dehydrogenase

    Energy Technology Data Exchange (ETDEWEB)

    Hu, Gang [Department of Biochemistry, University of Texas Health Science Center, San Antonio, TX 78229-3900 (United States); Taylor, Alexander B. [Department of Biochemistry, University of Texas Health Science Center, San Antonio, TX 78229-3900 (United States); X-ray Crystallography Core Laboratory, University of Texas Health Science Center, San Antonio, TX 78229-3900 (United States); McAlister-Henn, Lee [Department of Biochemistry, University of Texas Health Science Center, San Antonio, TX 78229-3900 (United States); Hart, P. John, E-mail: pjhart@biochem.uthscsa.edu [Department of Biochemistry, University of Texas Health Science Center, San Antonio, TX 78229-3900 (United States); X-ray Crystallography Core Laboratory, University of Texas Health Science Center, San Antonio, TX 78229-3900 (United States)

    2005-05-01

    Yeast NAD{sup +}-isocitrate dehydrogenase has been purified and crystallized using sodium citrate, a competitive inhibitor of the enzyme, as a precipitant. Preliminary X-ray analyses indicate the molecular boundaries of the molecule and large continuous solvent channels in the crystal. NAD{sup +}-specific isocitrate dehydrogenase (IDH; EC 1.1.1.41) is a complex allosterically regulated enzyme in the tricarboxylic acid cycle. Yeast IDH is believed to be an octamer containing four catalytic IDH2 and four regulatory IDH1 subunits. Crystals of yeast IDH have been obtained and optimized using sodium citrate, a competitive inhibitor of the enzyme, as the precipitating agent. The crystals belong to space group R3, with unit-cell parameters a = 302.0, c = 112.1 Å. Diffraction data were collected to 2.9 Å from a native crystal and to 4.0 Å using multiwavelength anomalous diffraction (MAD) methods from an osmium derivative. Initial electron-density maps reveal large solvent channels and the molecular boundaries of the allosteric IDH multimer.

  6. Quantitative wound healing studies using a portable, low cost, handheld near-infrared optical scanner: preliminary sensitivity and specificity analysis

    Science.gov (United States)

    Lei, Jiali; Rodriguez, Suset; Jayachandran, Maanasa; Solis, Elizabeth; Gonzalez, Stephanie; Perez-Clavijo, Francesco; Wigley, Stephen; Godavarty, Anuradha

    2016-03-01

    Lower extremity ulcers are devastating complications that are still un-recognized. To date, clinicians employ visual inspection of the wound site during its standard 4-week of healing process via monitoring of surface granulation. A novel ultra-portable near-infrared optical scanner (NIROS) has been developed at the Optical Imaging Laboratory that can perform non-contact 2D area imaging of the wound site. From preliminary studies it was observed that the nonhealing wounds had a greater absorption contrast with respect to the normal site, unlike in the healing wounds. Currently, non-contact near-infrared (NIR) imaging studies were carried out on 22 lower extremity wounds at two podiatric clinics, and the sensitivity and specificity of the scanner evaluated. A quantitative optical biometric was developed that differentiates healing from non-healing wounds, based on the threshold values obtained during ROC analysis. In addition, optical images of the wound obtained from weekly imaging studies are also assessed to determine the ability of the device to predict wound healing consistently on a periodic basis. This can potentially impact early intervention in the treatment of lower extremity ulcers when an objective and quantitative wound healing approach is developed. Lastly, the incorporation of MATLAB graphical user interface (GUI) to automate the process of image acquisition, image processing and image analysis realizes the potential of NIROS to perform non-contact and real-time imaging on lower extremity wounds.

  7. On the Enforcement of Specific Performance in Civil Law Countries

    DEFF Research Database (Denmark)

    Lando, Henrik; Rose, Caspar

    2003-01-01

    Abstract:Proponents of specific performance as a remedy for breach ofcontract have found support in the alleged use of the remedy inCivil Law countries. However, we provide evidence that specificperformance is in fact a rare remedy in Denmark, Germany andFrance, and under CISG, when performance...... these costs of enforcement. This is especiallyclear in the case of Denmark, where specific performance of actionshas been abandoned as a legal remedy.At the normative level, we argue that enforcement costs providesan additional rationale, over and above the rationales of the theoryof efficient breach...

  8. Analytical performance specifications for EQA schemes - need for harmonisation.

    Science.gov (United States)

    Dallas Jones, Graham Ross

    2015-05-01

    External Quality Assurance (EQA) is a vital tool in laboratory medicine to assess individual laboratory analytical performance and also the differences between the results from different laboratories. This information is also useful for professional bodies and manufacturers as part of post-market surveillance. The process involves the measurement of one or more samples by many laboratories and then assessment of the results. Individual results are generally assessed by how far they lie from a target, which may be established using reference methods or a median of some or all of the submitted results. The distance of a result from the target is compared with analytical performance specifications in order to assess the analytical quality. One of the uses of the Stockholm hierarchy of performance goals is to set the performance specifications for analysis of EQA results. Fifteen years after the Stockholm consensus meeting, EQA analytical performance specifications appear to still vary widely between EQA providers. This can be due to a range of factors, including the rationale for setting the criteria, the expected response to a failure to meet the specified performance, the clinical meaning behind meeting the specifications, and the possible need for further analytical improvements. There are also differences in the models chosen to set the criteria, usually either state of the art or biological variation, and then differences in how these are applied. While harmonisation of EQA performance specifications may be some time off, all EQA providers should define the nature of their specifications and the basis for their selection and make this information available to customers.

  9. Purification, characterization, and preliminary X-ray diffraction analysis of a lactose-specific lectin from Cymbosema roseum seeds.

    Science.gov (United States)

    Rocha, Bruno A M; Moreno, Frederico B M B; Delatorre, Plínio; Souza, Emmanuel P; Marinho, Emmanuel S; Benevides, Raquel G; Rustiguel, Joane Kathelen Rodrigues; Souza, Luis A G; Nagano, Celso S; Debray, Henri; Sampaio, Alexandre H; de Azevedo, Walter F; Cavada, Benildo S

    2009-03-01

    The unique carbohydrate-binding property of lectins makes them invaluable tools in biomedical research. Here, we report the purification, partial primary structure, carbohydrate affinity characterization, crystallization, and preliminary X-ray diffraction analysis of a lactose-specific lectin from Cymbosema roseum seeds (CRLII). Isolation and purification of CRLII was performed by a single step using a Sepharose-4B-lactose affinity chromatography column. The carbohydrate affinity characterization was carried using assays for hemagglutination activity and inhibition. CRLII showed hemagglutinating activity toward rabbit erythrocytes. O-glycoproteins from mucine mucopolysaccharides showed the most potent inhibition capacity at a minimum concentration of 1.2 microg mL(-1). Protein sequencing by mass spectrometry was obtained by the digestion of CRLII with trypsin, Glu-C, and AspN. CRLII partial protein sequence exhibits 46% similarity with the ConA-like alpha chain precursor. Suitable protein crystals were obtained with the hanging-drop vapor-diffusion method with 8% ethylene glycol, 0.1 M Tris-HCl pH 8.5, and 11% PEG 8,000. The monoclinic crystals belong to space group P2(1) with unit cell parameters a = 49.4, b = 89.6, and c = 100.8 A.

  10. Fort Hood Solar Total Energy Project. Volume II. Preliminary design. Part 2. System performance and supporting studies. Final report

    Energy Technology Data Exchange (ETDEWEB)

    None,

    1979-01-01

    The preliminary design developed for the Solar Total Energy System to be installed at Fort Hood, Texas, is presented. System performance analysis and evaluation are described. Feedback of completed performance analyses on current system design and operating philosophy is discussed. The basic computer simulation techniques and assumptions are described and the resulting energy displacement analysis is presented. Supporting technical studies are presented. These include health and safety and reliability assessments; solar collector component evaluation; weather analysis; and a review of selected trade studies which address significant design alternatives. Additional supporting studies which are generally specific to the installation site are reported. These include solar availability analysis; energy load measurements; environmental impact assessment; life cycle cost and economic analysis; heat transfer fluid testing; meteorological/solar station planning; and information dissemination. (WHK)

  11. A preliminary total-system performance assessment for the potential repository site Yucca Mountain

    Energy Technology Data Exchange (ETDEWEB)

    Wilson, M.L.; Barnard, R.W.; Dockerey, H.A. [Sandia National Labs., Albuquerque, NM (United States); Gauthier, J.H. [Spectra Research Inst., Albuquerque, NM (United States)

    1994-12-31

    We present a preliminary performance assessment of Yucca Mountain, Nevada, U.S.A., as a potential site for a radioactive-waste repository. Models and results are discussed for four basic categories of processes and events: groundwater flow and aqueous transport, gas flow and gaseous transport, human intrusion, and basaltic volcanism. Calculated releases of radioactivity to the accessible environment are compared with U.S. Environmental Protection Agency requirements. The preliminary results show releases from human intrusion and volcanisms to fall well below the regulatory limits, though not all aspects of those categories have yet been considered. Calculated releases for nominal gaseous transport (of {sup 14}CO{sub 2}) are closest to the limits, indicating that models and data relating to gaseous releases may need to receive higher priority. (author) 15 figs., 33 refs.

  12. Transitioning from conceptual design to construction performance specification

    Science.gov (United States)

    Jeffers, Paul; Warner, Mark; Craig, Simon; Hubbard, Robert; Marshall, Heather

    2012-09-01

    On successful completion of a conceptual design review by a funding agency or customer, there is a transition phase before construction contracts can be placed. The nature of this transition phase depends on the Project's approach to construction and the particular subsystem being considered. There are generically two approaches; project retention of design authority and issuance of build to print contracts, or issuance of subsystem performance specifications with controlled interfaces. This paper relates to the latter where a proof of concept (conceptual or reference design) is translated into performance based sub-system specifications for competitive tender. This translation is not a straightforward process and there are a number of different issues to consider in the process. This paper deals with primarily the Telescope mount and Enclosure subsystems. The main subjects considered in this paper are: • Typical status of design at Conceptual Design Review compared with the desired status of Specifications and Interface Control Documents at Request for Quotation. • Options for capture and tracking of system requirements flow down from science / operating requirements and sub-system requirements, and functional requirements derived from reference design. • Requirements that may come specifically from the contracting approach. • Methods for effective use of reference design work without compromising a performance based specification. • Management of project team's expectation relating to design. • Effects on cost estimates from reference design to actual. This paper is based on experience and lessons learned through this process on both the VISTA and the ATST projects.

  13. Development and preliminary evaluation of culturally specific web-based intervention for parents of adolescents.

    Science.gov (United States)

    Choi, H; Kim, S; Ko, H; Kim, Y; Park, C G

    2016-10-01

    WHAT IS KNOWN ON THE SUBJECT?: Problematic parent-child relationships have been identified as one of the main predictors of adolescents' mental health problems, but there are few existing interventions that address this issue. The format and delivery method of existing interventions for parents are relatively inaccessible for parents with full-time jobs and families living in rural areas. WHAT DOES THIS PAPER ADD TO EXISTING KNOWLEDGE?: The newly developed 'Stepping Stone' culturally specific web-based intervention, which is intended to help Korean parents of adolescents to acquire both knowledge and communication and conflict management skills, was found to be feasible and well-accepted by parents. This study enabled us to identify areas for improvement in the content and format of the intervention and strategies. This will potentially increase effect sizes for the outcome variables of parents' perception and behaviours. WHAT ARE THE IMPLICATIONS FOR PRACTICE?: This web-based intervention could be delivered across diverse settings, such as schools and community mental health centers, to increase parents' knowledge of adolescent's mental health and allow for early detection of mental health problems. Mental health nurses working in schools may spend a significant amount of time addressing students' mental health issues; thus, this web-based intervention could be a useful resource to share with parents and children. In this way, the mental health nurses could facilitate parental engagement in the intervention and then help them to continue to apply and practice the knowledge and skills obtained through the program. Introduction There is a need for accessible, culturally specific web-based interventions to address parent-child relationships and adolescents' mental health. Aims This study developed and conducted a preliminary evaluation of a 4-week web-based intervention for parents of adolescents aged 11 to 16 years in Korea. Methods We used a two-group, repeated

  14. Performance specifications: the nearly impossible versus the merely difficult

    Science.gov (United States)

    Hopper, Darrel G.

    2000-08-01

    Affordability is the objective of acquisition reform. The institution of 'performance' specifications in lieu of 'design' specifications is a key strategy. Design of a cockpit display, for example, is left to the prime contractor based on a performance requirement stated by the government. The prime delegates to the integrator. The integrator develops the display and bill of materials provided by vendors. There is no feedback loop from the vendors to the ultimate customer, the government. As a result of this situation a communication gap exists: the government, primes, and integrators have concluded that they should pay commodity prices for custom displays. One step in the closing of this gap is the establishment of cross- cutting common reference performance specifications for aerospace and defense displays. The performance specification for cockpit displays is nearly impossible to achieve -- the last ounce of technology and more is required. Commodity markets, such as consumer notebook computers, are based on but a fraction of currently available technology -- companies 'bank' technology and roll it out across several 18-month product generations. Ruggedized consumer displays can be used in aerospace and defense applications other than the cockpit, such as mission crew stations. The performance specification for non-cockpit aerospace and defense applications is merely difficult. Acquisition reform has been defined by the Secretary of Defense to mean DoD should leverage the commercial market to the maximal extent possible. For the achievement of this end, an entirely different approach is wanted for cockpit displays versus large platform mission displays. That is, the nearly impossible requires a different design and business approach from the merely difficult.

  15. Performance assessment methodology as applied to the Greater Confinement Disposal site: Preliminary results of the third performance iteration

    Energy Technology Data Exchange (ETDEWEB)

    Brown, T.J. [Sandia National Labs., Albuquerque, NM (United States); Baer, T.A. [GRAM Inc., Albuquerque, NM (United States)

    1994-12-31

    The US Department of Energy has contracted Sandia National Laboratories to conduct a performance assessment of the Greater Confinement Disposal facility, Nevada. The performance assessment is an iterative process in which transport models are used to prioritize site characterization data collection. Then the data are used to refine the conceptual and performance assessment models. The results of the first two performance assessment iterations indicate that the site is likely to comply with the performance standards under the existing hydrologic conditions. The third performance iteration expands the conceptual model of the existing transport system to include possible future events and incorporates these processes in the performance assessment models. The processes included in the third performance assessment are climate change, bioturbation, plant uptake, erosion, upward advection, human intrusion and subsidence. The work completed to date incorporates the effects of bioturbation, erosion and subsidence in the performance assessment model. Preliminary analyses indicate that the development of relatively deep-rooting plant species at the site, which could occur due to climate change, irrigated farming or subsidence, poses the greatest threat to the site`s performance.

  16. Near-term hybrid vehicle program, phase 1. Appendix A: Mission analysis and performance specification studies report

    Science.gov (United States)

    1979-01-01

    Results of a study leading to the preliminary design of a five passenger hybrid vehicle utilizing two energy sources (electricity and gasoline/diesel fuel) to minimize petroleum usage on a fleet basis are presented. The study methodology is described. Vehicle characterizations, the mission description, characterization, and impact on potential sales, and the rationale for the selection of the reference internal combustion engine vehicle are presented. Conclusions and recommendations of the mission analysis and performance specification report are included.

  17. Preliminary Evaluation of PGSFR DHR Heat Exchangers Performance Using STELLA-1 Facility

    Energy Technology Data Exchange (ETDEWEB)

    Hong, Jonggan; Eoh, Jae-Hyuk; Yeom, Sujin; Lee, Jewhan; Kim, Tae-Joon; Hwang, Inkoo; Cho, Chungho; Kim, Jong-Man; Cho, Youngil; Jung, Min-Hwan; Gam, Da-Young; Jeong, Ji-Young [Korean Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2014-10-15

    The STELLA program for PGSFR decay heat removal (DHR) performance demonstration is in progress at KAERI. As the first phase of the program, the STELLA-1 facility has been constructed and separate effect tests for heat exchangers of DHRS have been conducted. Two kinds of heat exchangers including a shell-and-tube type sodium-to-sodium heat exchanger (DHX) and a helical-tube type sodium-to-air heat exchanger (AHX) were tested for design codes V-V, e.g. SHXSA and AHXSA. In this paper, firstly, overall characteristics of the STELLA-1 facility are described briefly. Secondly, the performance tests of the DHX and AHX rely on a steady-state result of a heat transfer experiment. Thus experimental procedures to obtain the steady-state result are described and steady-state conditions for the heat exchanger performance test are clearly defined. Lastly, experimental results and calculation results obtained from the design codes are also compared as a preliminary work for the design code V-V. The PGSFR DHR heat exchangers performance was experimentally demonstrated using the STELLA-1 facility, and the experimental results and the prediction of the design code were compared as a preliminary work for the design code V-V. The experimental results of the DHX and AHX were in good agreement with the estimation of the SHXSA and AHXSA codes, respectively.

  18. A Preliminary Analysis of Reactor Performance Test (LOEP) for a Research Reactor

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Hyeonil; Park, Su-Ki [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2015-10-15

    The final phase of commissioning is reactor performance test, which is to prove the integrated performance and safety of the research reactor at full power with fuel loaded such as neutron power calibration, Control Absorber Rod/Second Shutdown Rod drop time, InC function test, Criticality, Rod worth, Core heat removal with natural mechanism, and so forth. The last test will be safety-related one to assure the result of the safety analysis of the research reactor is marginal enough to be sure about the nuclear safety by showing the reactor satisfies the acceptance criteria of the safety functions such as for reactivity control, maintenance of auxiliaries, reactor pool water inventory control, core heat removal, and confinement isolation. After all, the fuel integrity will be ensured by verifying there is no meaningful change in the radiation levels. To confirm the performance of safety equipment, loss of normal electric power (LOEP), possibly categorized as Anticipated Operational Occurrence (AOO), is selected as a key experiment to figure out how safe the research reactor is before turning over the research reactor to the owner. This paper presents a preliminary analysis of the reactor performance test (LOEP) for a research reactor. The results showed how different the transient between conservative estimate and best estimate will look. Preliminary analyses have shown all probable thermal-hydraulic transient behavior of importance as to opening of flap valve, minimum critical heat flux ratio, the change of flow direction, and important values of thermal-hydraulic parameters.

  19. Preliminary study to improve the performance of SCWR-M during loss-of-flow accident

    Energy Technology Data Exchange (ETDEWEB)

    Liu, X.J., E-mail: xiaojingliu@sjtu.edu.cn [School of Nuclear Science and Engineering, Shanghai Jiao Tong University, 800 Dong Chuan Road, Shanghai 200240 (China); Sun, C.; Wang, Z.D.; Chai, X.; Xiong, J.B.; Yang, Y.H. [School of Nuclear Science and Engineering, Shanghai Jiao Tong University, 800 Dong Chuan Road, Shanghai 200240 (China); Cheng, X. [Institute of Fusion and Nuclear Technology, Karlsruhe Institute of Technology (KIT), Kaiserstr. 12, 76131 Karlsruhe (Germany)

    2016-10-15

    Highlights: • Validation of the ATHLET-SC code to the safety analysis for SCWR. • Loss of flow accident analysis for SCWR-M is performed. • The passive design parameter is optimized. • The optimized SCWR-M design shows a better safety performance. - Abstract: The SCWR-M is one of the conceptual core designs with mixed neutron spectrum (fast and thermal), which is developed at Shanghai Jiao Tong University. Some preliminary calculations of this new conceptual SCWR indicate the SCWR-M system gets better safety characteristics compared to other single spectrum supercritical water cooled reactors. Loss of flow accident (LOFA) is of particular importance among the abnormal events and accidents for SCWR-M. In order to perform the preliminary study to improve the current SCWR-M safety design, this paper presents the validation results of the ATHLET-SC code and optimization work for safety system design parameters of the ICS, ACC, GDCS based on LOFA analysis. The better performance of the optimized design parameters are demonstrated by comparison with the previous design.

  20. Preliminary performance analysis of a transverse flow spectrally selective two-slab packed bed volumetric receiver

    CSIR Research Space (South Africa)

    Roos, TH

    2016-05-01

    Full Text Available stream_source_info Roos_2016_ABSTRACT.pdf.txt stream_content_type text/plain stream_size 2694 Content-Encoding UTF-8 stream_name Roos_2016_ABSTRACT.pdf.txt Content-Type text/plain; charset=UTF-8 21st SolarPACES... International Conference (SolarPACES 2015), 13-16 October 2015 Preliminary Performance Analysis of a Transverse Flow Spectrally Selective Two-slab Packed Bed Volumetric Receiver Thomas H. Roos1, a) and Thomas M. Harms2, b) 1Aeronautical Systems...

  1. Development of the wireless ultra-miniaturized inertial measurement unit WB-4: preliminary performance evaluation.

    Science.gov (United States)

    Lin, Zhuohua; Zecca, Massimiliano; Sessa, Salvatore; Bartolomeo, Luca; Ishii, Hiroyuki; Takanishi, Atsuo

    2011-01-01

    This paper presents the preliminary performance evaluation of our new wireless ultra-miniaturized inertial measurement unit (IMU) WB-4 by compared with the Vicon motion capture system. The WB-4 IMU primarily contains a mother board for motion sensing, a Bluetooth module for wireless data transmission with PC, and a Li-Polymer battery for power supply. The mother board is provided with a microcontroller and 9-axis inertial sensors (miniaturized MEMS accelerometer, gyroscope and magnetometer) to measure orientation. A quaternion-based extended Kalman filter (EKF) integrated with an R-Adaptive algorithm for automatic estimation of the measurement covariance matrix is implemented for the sensor fusion to retrieve the attitude. The experimental results showed that the wireless ultra-miniaturized WB-4 IMU could provide high accuracy performance at the angles of roll and pitch. The yaw angle which has reasonable performance needs to be further evaluated.

  2. Preliminary Evaluation of MapReduce for High-Performance Climate Data Analysis

    Science.gov (United States)

    Duffy, D. Q.; Schnase, J. L.; Clune, T. L.; Kim, E. J.; Freeman, S. M.; Thompson, J. H.; Hunter, K. A.; Theriot, M. E.

    2011-12-01

    Data intensive analytic workflows bridge between the largely unstructured mass of stored scientific data and the highly structured, tailored, reduced, and refined products used by scientists in their research. In general, the initial steps of an analysis, those operations that first interact with a data repository, tend to be the most general, while data manipulations closer to the client tend to be the most specialized to the individual, to the domain, or to the science question under study. The amount of data being operated on also tends to be larger on the repository-side of the workflow, smaller toward the client-side end products. We are using MapReduce to exploit this natural stratification, optimize efficiencies along the workflow chain, and provide a preliminary qualitative and quantitative assessment of MapReduce as a means of enabling server-side, distributed climate data analysis. MapReduce is a model for distributed storage and computation that seeks to improve efficiencies of the near-archive operations that initiate workflows. Simply put, MapReduce stores chunked data on disks with associated processors in such a way that operations on the chunked data can occur in parallel and return meaningfully aggregated results. While MapReduce has proven effective for large repositories of textual data, its use in data intensive science applications has been limited, because many scientific data sets are inherently complex, have high dimensionality, and use binary formats. We are using Apache's open-source Hadoop software implementation of MapReduce on top of the Hadoop Filesystem in our evaluation. Our analyses focus on soil moisture, precipitation, and atmospheric water-vapor, important classes of observation- and simulation-derived data products. The specific data sets being used in the evaluation include MERRA monthly precipitation and soil moisture products; the MODIS Atmospheres, 8-day global water-vapor product; and the SMOS 3-day global soil moisture

  3. Industrial cogeneration optimization program. Volume II. Appendix A. Conceptual designs and preliminary equipment specifications. Appendix B. Characterization of cogeneration systems (near-term technology). Appendix C. Optimized cogeneration systems

    Energy Technology Data Exchange (ETDEWEB)

    1980-01-01

    This appendix to a report which evaluates the technical, economic, and institutional aspects of industrial cogeneration for conserving energy in the food, chemical, textile, paper, and petroleum industries contains data, descriptions, and diagrams on conceptual designs and preliminary equipment specifications for cogeneration facilities; characterization of cogeneration systems in terms of fuel utilization, performance, air pollution control, thermal energy storage systems, and capital equipment costs; and optimized cogeneration systems for specific industrial plants. (LCL)

  4. Preliminary Design Report of Fluid System of PDRC Performance Test Facility

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Tae-Ho; Eoh, Jae-Hyuk; Seong, Seung-Hwan; Han, Ji-Woong; Choi, Byoung-Hae; Kim, Seong-O

    2008-10-15

    PDRC (Passive Decay Heat Removal Circuit) is a safety grade passive residual heat removal system of KALIMER-600. In order to assess the long- and short-term cooling capabilities of PDRC and produce the experimental data for the verification of the performance and safety analysis codes, PDRC performance test was planned for. In this study, the overall design requirements and the preliminary design data for the fluid system of test facility are presented. The fluid system of the facility is composed of the primary heat transport system, the PDRC, the IHX air cooling system and the sodium supply/purification system. The preliminarily designed facility is scaled-down to 1/4 for length, 1/400 for volume from the primary heat transport system and the PDRC of KALIMER-600 based on a reliable scaling method. It can simulate the cooling of primary heat transport system for the full temperature condition in case of the reactor and pump trips. The produced preliminary design data will be used in the future as the basic information for a detailed design, an establishment of experimental requirement and an assessment of the appropriateness of facility design.

  5. Advanced Wet Tantalum Capacitors: Design, Specifications and Performance

    Science.gov (United States)

    Teverovsky, Alexander

    2017-01-01

    Insertion of new types of commercial, high volumetric efficiency wet tantalum capacitors in space systems requires reassessment of the existing quality assurance approaches that have been developed for capacitors manufactured to MIL-PRF-39006 requirements. The specifics of wet electrolytic capacitors is that leakage currents flowing through electrolyte can cause gas generation resulting in building up of internal gas pressure and rupture of the case. The risk associated with excessive leakage currents and increased pressure is greater for high value advanced wet tantalum capacitors, but it has not been properly evaluated yet. This presentation gives a review of specifics of the design, performance, and potential reliability risks associated with advanced wet tantalum capacitors. Problems related to setting adequate requirements for DPA, leakage currents, hermeticity, stability at low and high temperatures, ripple currents for parts operating in vacuum, and random vibration testing are discussed. Recommendations for screening and qualification to reduce risks of failures have been suggested.

  6. Alcohol elimination and simulator performance of male and female aviators: a preliminary report.

    Science.gov (United States)

    Taylor, J L; Dolhert, N; Friedman, L; Mumenthaler, M; Yesavage, J A

    1996-05-01

    In this preliminary study of alcohol effects on aviators' flight simulator performance, we addressed some methodological issues regarding possible gender-related differences in response to alcohol. Subjects were 11 male and 12 female general aviation pilots, ages 21-40. Subjects received 8 h of training before they were tested with alcohol. On the alcohol test day they were tested before drinking, while intoxicated (target BAC of 0.08%), and 8 h after drinking. The average, observed peak BAC readings for men and women were within 0.003% of each other. We observed faster disappearance rates for women such that women reached the FAA cutoff of 0.04% approximately 1 h before men, on average. Compared to predrink performance, there was a significant decrement in simulator performance during acute intoxication, but not 8 h after drinking. There were no significant gender differences in performance before or after drinking alcohol. Slower rates of alcohol elimination were associated with larger performance changes 8 h after drinking. This is the first report to our knowledge suggesting a possible relation between alcohol elimination rate and change in performance after drinking alcohol. A 12.5% dose reduction for women appears to be adequate for achieving comparable peak BAC's for male and female groups. Future studies using measures of circadian rhythmicity in conjunction with pharmacokinetic and performance measures could potentially shed light on differences in subjects' acute and delayed responses to alcohol.

  7. Do district health systems perform differently because of their managers? Preliminary insights from Indonesia

    Directory of Open Access Journals (Sweden)

    Augustine Asante

    2015-07-01

    Full Text Available District health systems (DHS are central to the global efforts to improve health outcomes but many remain ineffective. In many lowresource settings, despite the generally weak DHS there is evidence that some districts consistently perform well against the odds, and this is often attributed to the calibre of managers leading such districts and their management and leadership (M&L skills. This paper examines the M&L practices of district health managers in high and low performing districts in Indonesia in an attempt to understand whether the differences in the performance of DHS can be explained, at least in part, by the differences in the performance of their health managers. We employed a mixed methods case study design focusing on two purposefully selected districts. Data were collected in 2011 using questionnaires and in-depth interviews. The preliminary results suggest that M&L practices of managers in the high and low performing districts are similar and provide little explanation for the differences in the performance of the two DHS. Contextual and health system factors offered a much better explanation for the variations in DHS performance.

  8. Validating a dance-specific screening test for balance: preliminary results from multisite testing.

    Science.gov (United States)

    Batson, Glenna

    2010-09-01

    Few dance-specific screening tools adequately capture balance. The aim of this study was to administer and modify the Star Excursion Balance Test (oSEBT) to examine its utility as a balance screen for dancers. The oSEBT involves standing on one leg while lightly targeting with the opposite foot to the farthest distance along eight spokes of a star-shaped grid. This task simulates dance in the spatial pattern and movement quality of the gesturing limb. The oSEBT was validated for distance on athletes with history of ankle sprain. Thirty-three dancers (age 20.1 +/- 1.4 yrs) participated from two contemporary dance conservatories (UK and US), with or without a history of lower extremity injury. Dancers were verbally instructed (without physical demonstration) to execute the oSEBT and four modifications (mSEBT): timed (speed), timed with cognitive interference (answering questions aloud), and sensory disadvantaging (foam mat). Stepping strategies were tracked and performance strategies video-recorded. Unlike the oSEBT results, distances reached were not significant statistically (p = 0.05) or descriptively (i.e., shorter) for either group. Performance styles varied widely, despite sample homogeneity and instructions to control for strategy. Descriptive analysis of mSEBT showed an increased number of near-falls and decreased timing on the injured limb. Dancers appeared to employ variable strategies to keep balance during this test. Quantitative analysis is warranted to define balance strategies for further validation of SEBT modifications to determine its utility as a balance screening tool.

  9. Visual Assessment on Coastal Cruise Tourism: A Preliminary Planning Using Importance Performance Analysis

    Science.gov (United States)

    Trisutomo, S.

    2017-07-01

    Importance-Performance Analysis (IPA) has been widely applied in many cases. In this research, IPA was applied to measure perceive on coastal tourism objects and its possibility to be developed as coastal cruise tourism in Makassar. Three objects, i.e. Akkarena recreational site, Losari public space at waterfront, and Paotere traditional Phinisi ships port, were selected and assessed visually from water area by a group of purposive resource persons. The importance and performance of 10 attributes of each site were scored using Likert scale from 1 to 5. Data were processed by SPSS-21 than resulted Cartesian graph which the scores were divided in four quadrants: Quadrant I concentric here, Quadrant II keep up the good work, Quadrant III low priority, and Quadrant IV possible overkill. The attributes in each quadrant could be considered as the platform for preliminary planning of coastal cruise tour in Makassar

  10. Preliminary performance assessment for the Waste Isolation Pilot Plant, December 1992. Volume 3, Model parameters: Sandia WIPP Project

    Energy Technology Data Exchange (ETDEWEB)

    1992-12-29

    This volume documents model parameters chosen as of July 1992 that were used by the Performance Assessment Department of Sandia National Laboratories in its 1992 preliminary performance assessment of the Waste Isolation Pilot Plant (WIPP). Ranges and distributions for about 300 modeling parameters in the current secondary data base are presented in tables for the geologic and engineered barriers, global materials (e.g., fluid properties), and agents that act upon the WIPP disposal system such as climate variability and human-intrusion boreholes. The 49 parameters sampled in the 1992 Preliminary Performance Assessment are given special emphasis with tables and graphics that provide insight and sources of data for each parameter.

  11. A preliminary biophysical analysis of site-specific mutations in the photosystem II reaction center of the cyanobacterium Synechocystis 6803

    Energy Technology Data Exchange (ETDEWEB)

    Sithole, I.; Bowlby, N.; Babcock, G.T.; McIntosh, L. (Michigan State Univ., East Lansing (USA))

    1990-05-01

    In an attempt to identify ligands for the manganese cluster and understand the conformational constraints around Ya{sup +}; we have generated a series of site-specific mutations in the psbA and psbD genes of Synechocystis PCC 6803, specifically at aspartate and glutamate residues in the AB interhelical region of the D1 and D2 polypeptides; and P162D1, P161D2, W167D2 and F168D1 in the vicinity of Yz{sup +}. One of these mutations is lethal and only grows photoheterotrophically in the presence of glucose, and the remainder have an altered oxygen evolution rate but are capable of photoautotrophic growth in the absence of glucose. Preliminary biochemical and spectroscopic data will be presented.

  12. A preliminary approach to the extension of the Transuranus code to the fuel rod performance analysis of HLM-cooled nuclear reactors

    Energy Technology Data Exchange (ETDEWEB)

    Luzzi, L.; Botazzoli, P.; Devita, M.; Di Marcello, V.; Pastore, G. [Department of Energy, Politecnico di Milano, Enrico Fermi Center for Nuclear Studies - CeSNEF, via Ponzio 34/3, 20133 Milano (Italy)

    2010-07-01

    This paper briefly presents a preliminary modelling approach, aimed at the extension of the TRANSURANUS code to the fuel rod performance analysis of Heavy Liquid Metal (HLM) cooled nuclear reactors, with specific reference to the employment of the T91 steel as cladding material and of the liquid Lead-Bismuth Eutectic (LBE) as coolant. On the basis of literature indications, correlations for heat transfer to LBE, corrosion behaviour and thermo-mechanical properties of T91 are proposed, and some open issues are discussed in prospect of more reliable fuel rod performance analysis of HLM-cooled nuclear reactors. (authors)

  13. Turkish children's Bender-Gestalt Test performance: a pilot study and preliminary norms.

    Science.gov (United States)

    Ozer, Serap

    2007-12-01

    The present study was undertaken to provide preliminary data for norms on the Bender-Gestalt Test for 253 children ages 5 yr., 5 mo. to 11 yr., 10 mo. in Turkey. The Koppitz Developmental Scoring System gave mean error scores of 4.2 (SD = 3.3) for girls and 3.6 (SD = 3.0) for boys. The mean error scores obtained by all age groups are presented and compared with other cross-cultural data. These scores decreased across age groups, supporting Bender's maturational hypothesis of the test. The present sample performed at a higher developmental level than the Koppitz normative sample for the 5- and 6-year age groups, while means for other age groups were similar to the original U.S. norms. That this pattern is supported in other cross-cultural studies is discussed as well as the importance of developing local norms for visual spatial tests.

  14. Kinematic analysis of motor performance in robot-assisted surgery: a preliminary study.

    Science.gov (United States)

    Nisky, Ilana; Patil, Sangram; Hsieh, Michael H; Okamura, Allison M

    2013-01-01

    The inherent dynamics of the master manipulator of a teleoperated robot-assisted surgery (RAS) system can affect the movements of a human operator, in comparison with free-space movements. To measure the effects of these dynamics on operators with differing levels of surgical expertise, a da Vinci Si system was instrumented with a custom surgeon grip fixture and magnetic pose trackers. We compared users' performance of canonical motor control movements during teleoperation with the manipulator and freehand cursor control, and found significant differences in several aspects of motion, including target acquisition error, movement speed, and acceleration. In addition, there was preliminary evidence for differences between experts and novices. These findings could impact robot design, control, and training methods for RAS.

  15. Preliminary Evaluation of MapReduce for High-Performance Climate Data Analysis

    Science.gov (United States)

    Duffy, Daniel Q.; Schnase, John L.; Thompson, John H.; Freeman, Shawn M.; Clune, Thomas L.

    2012-01-01

    MapReduce is an approach to high-performance analytics that may be useful to data intensive problems in climate research. It offers an analysis paradigm that uses clusters of computers and combines distributed storage of large data sets with parallel computation. We are particularly interested in the potential of MapReduce to speed up basic operations common to a wide range of analyses. In order to evaluate this potential, we are prototyping a series of canonical MapReduce operations over a test suite of observational and climate simulation datasets. Our initial focus has been on averaging operations over arbitrary spatial and temporal extents within Modern Era Retrospective- Analysis for Research and Applications (MERRA) data. Preliminary results suggest this approach can improve efficiencies within data intensive analytic workflows.

  16. Preliminary performance analysis of the advanced pulse compression noise radar waveform

    Science.gov (United States)

    Govoni, Mark A.; Moyer, Lee R.

    2012-06-01

    Noise radar systems encounter target fluctuation behavior similar to that of conventional systems. For noise radar systems, however, the fluctuations are not only dictated by target composition and geometry, but also by the non-uniform power envelope of their random transmit signals. This third dependency is of interest and serves as the basis for the preliminary analysis conducted in this manuscript. General conclusions are drawn on the implications of having a random power envelope and the impacts it could have on both the transmit and receive processes. Using an advanced pulse compression noise (APCN) radar waveform as the constituent signal, a computer simulation aids in quantifying potential losses and the impacts they might have on the detection performance of a real radar system.

  17. Liquid Argon Calorimetry with LHC-Performance Specifications

    CERN Multimedia

    2002-01-01

    % RD-3 Liquid Argon Calorimetry with LHC-Performance Specifications \\\\ \\\\Good electromagnetic and hadronic calorimetry will play a central role in an LHC detector. Among the techniques used so far, or under development, the liquid argon sampling calorimetry offers high radiation resistence, good energy resolution (electromagnetic and hadronic), excellent calibration stability and response uniformity. Its rate capabilities, however, do not yet match the requirements for LHC. \\\\ \\\\The aim of this proposal is to improve the technique in such a way that high granularity, good hermiticity and adequate rate capabilities are obtained, without compromising the above mentioned properties. To reach this goal, we propose to use a novel structure, the $^{\\prime\\prime}$accordion$^{\\prime\\prime}$, coupled to fast preamplifiers working at liquid argon temperature. Converter and readout electrodes are no longer planar and perpendicular to particles, as usual, but instead they are wiggled around a plane containing particles. ...

  18. Application Specific Performance Technology for Productive Parallel Computing

    Energy Technology Data Exchange (ETDEWEB)

    Malony, Allen D. [Univ. of Oregon, Eugene, OR (United States); Shende, Sameer [Univ. of Oregon, Eugene, OR (United States)

    2008-09-30

    Our accomplishments over the last three years of the DOE project Application- Specific Performance Technology for Productive Parallel Computing (DOE Agreement: DE-FG02-05ER25680) are described below. The project will have met all of its objectives by the time of its completion at the end of September, 2008. Two extensive yearly progress reports were produced in in March 2006 and 2007 and were previously submitted to the DOE Office of Advanced Scientific Computing Research (OASCR). Following an overview of the objectives of the project, we summarize for each of the project areas the achievements in the first two years, and then describe in some more detail the project accomplishments this past year. At the end, we discuss the relationship of the proposed renewal application to the work done on the current project.

  19. Performance Analysis of Different MANET Specific TCP variants

    Directory of Open Access Journals (Sweden)

    Debajyoti Pal

    2012-09-01

    Full Text Available - Transmission Control Protocol(TCP is implemented in the transport layer of a MANET, which enjoys the advantage of reliable data transmission over the Internet. However, due to certain unique characteristics of a MANET, modification of classical TCP has been done so as to improve its performance in such an environment. Accordingly, several MANET specific TCP versions like TCP Reno, TCP New Reno, TCP Tahoe and TCP Vegas have come into prominence. This paper evaluates the performance of the different TCP versions for the same network topology over certain fixed parameters like number of packets generated/node, average packet loss, average delay incurred by the packets while in transit from source to destination and the processing time taken by the intermediate nodes. For routing purpose, we have assumed Ad-HocOn Demand Distance Vector Routing (AODV as the standard. To address the common issues of congestion control as with TCP, the experiment has been carried out under different network loading conditions that have been achieved by slowly increasing the node density.

  20. The effects of specific preconditioning activities on acute sprint performance.

    Science.gov (United States)

    Guggenheimer, Joshua D; Dickin, D Clark; Reyes, Gabriel F; Dolny, Dennis G

    2009-07-01

    Previous research suggests that specific preconditioning activities such as whole-body vibration (WBV) and resistance training may play an important role in ensuing dynamic activities. The purpose of this study was to examine the effects of 2 preconditioning activities, WBV and power cleans (PC), on acute sprint performance. Two studies were conducted in which 14 (WBV) and 9 (PC) male track and field athletes were subjects. The WBV treatment consisted of 4 bouts of 5 seconds of high-knee running on a vibrating platform at 0, 30, 40, or 50 Hz. The PC treatment consisted of 3 PC reps at 90% 1RM. In both cases, acute sprint performance was the dependent variable of interest. For WBV, split times were recorded at 10, 20, and 40 m. Reaction times (RXN) as well as 5-, 10-, and 40-m split times were recorded for the PC study. Results indicated no significant differences between treatment and nontreatment groups for both studies. However, significant correlations were present between RXN and 5-m splits (r = 0.65) and RXN and 10-m splits (r = 0.63), although they decreased as a function of sprint distance to r = 0.43 at 40 m. These results suggest little efficacy for the use of WBV and PC as a means of augmenting acute sprint performance. However, a trend within the 30-Hz protocol may suggest that WBV as part of a warm-up for sprinting activities greater than 40 m (i.e., 100 m) could potentially result in a decreased sprint time of nearly 1/10th of a second, which is worth future consideration.

  1. Preliminary characterisation of Toxoplasma gondii isolates from Zimbabwe, with stage-specific monoclonal antibodies

    DEFF Research Database (Denmark)

    Hove, T.; Lind, Peter; Mukaratirwa, S.

    2005-01-01

    Cell-culture-derived clones of eight Toxoplasma gondii isolates from Zimbabwe were characterised in IFAT with a panel of five monoclonal antibodies (mAb). Each clone had been established from a single murine brain cyst. The antibodies were bradyzoite-specific (4.3), tachyzoite-specific (4.25, 5.1...... in the IFAT in a similar way to the Danish reference strain of T. gondii, SSI-119....

  2. A preliminary study on the association between ventilation rates in classrooms and student performance.

    Science.gov (United States)

    Shaughnessy, R J; Haverinen-Shaughnessy, U; Nevalainen, A; Moschandreas, D

    2006-12-01

    Poor conditions leading to substandard indoor air quality (IAQ) in classrooms have been frequently cited in the literature over the past two decades. However, there is limited data linking poor IAQ in the classrooms to student performance. Whereas, it is assumed that poor IAQ results in reduced attendance and learning potential, and subsequent poor student performance, validating this hypothesis presents a challenge in today's school environment. This study explores the association between student performance on standardized aptitude tests that are administered to students on a yearly basis, to classroom carbon dioxide (CO2) concentrations, which provide a surrogate of ventilation being provided to each room. Data on classroom CO2 concentrations (over a 4-5 h time span within a typical school day) were recorded in fifth grade classrooms in 54 elementary schools within a school district in the USA. Results from this preliminary study yield a significant (P classroom-level ventilation rate and test results in math. They also indicate that non-linear effects may need to be considered for better representation of the association. A larger sample size is required in order to draw more definitive conclusions. Practical Implications Future studies could focus on (1) gathering more evidence on the possible association between classroom ventilation rates and students' academic performance; (2) the linear/non-linear nature of the association; and (3) whether it is possible to detect 'no observed adverse effect level' for adequate ventilation with respect to academic performance in schools. All of this information could be used to improve guidance and take regulatory actions to ensure adequate ventilation in schools. The high prevalence of low ventilation rates, combined with the growing evidence of the positive impact that sufficient ventilation has on human performance, suggests an opportunity for improving design and management of school facilities.

  3. Barrier analogs: Long-term performance issues, preliminary studies, and recommendations

    Energy Technology Data Exchange (ETDEWEB)

    Waugh, W.J. [Rust Geotech, Inc., Grand Junction, CO (United States). Environmental Sciences Lab.; Chatters, J.C.; Last, G.V.; Bjornstad, B.N.; Link, S.O. [Pacific Northwest Lab., Richland, WA (United States); Hunter, C.R. [Cascade Earth Sciences, La Grande, OR (United States)

    1994-02-01

    The US Department of Energy`s Hanford Protective Barrier Development Program is funding studies of natural analogs of the long-term performance of waste site covers. Natural-analog studies examine past environments as evidence for projecting the future performance of engineered structures. The information generated by analog studies is needed to (1) evaluate the designs and results of short term experiments and demonstrations, (2) formulate performance-modeling problems that bound expected changes in waste site environments, and (3) understand emergent system attributes that cannot be evaluated with short-term experiments or computer models. Waste site covers will be part of dynamic environmental systems with attributes that transcend the traits of engineered components. This report discusses results of the previously unreported preliminary studies conducted in 1983 and 1984. These results indicate that analogs could play an important role in predicting the long-term behavior of engineered waste covers. Layered exposures of glacial-flood-deposited gravels mantled with silt or sand that resemble contemporary barrier designs were examined. Bergmounds, another anomaly left by cataclysmic glacial floods, were also examined as analogs of surface gravel.

  4. The Preliminary Research for Implementation of Improved DTC Scheme of High Performance PMSM Drives

    Directory of Open Access Journals (Sweden)

    Tole Sutikno

    2008-12-01

    Full Text Available The direct torque control (DTC is one of control approache that is used commonly in PMSM control system. This method supports a very quick and precise torque response. However, the DTC method is not perfect and has some disadvantages. Many researchers have been proposed to modify the basic DTC scheme for PMSM drive. All this contributions allow performance to be improved, but at the same time they lead to more complex schemes. Furthermore, the PMSM drive control systems are usually based on microcontroller and DSP. Some researchers also have been used DSP and FPGA together to develop DTC for AC drives. These allow improving the performance, but they will increase cost. For the reason above, this paper proposed a new DTC scheme to apply only based on FPGA. The preliminary research showed that the proposed DTC sheme can reduce torque and flux ripples significantly. Therefore, this paper also recomend to realize proposed DTC scheme based on FPGA in order to support to execute very fast computation.The implementation is hoped that it will very potential to replace not only the induction motor but also the DC servo motor in a number of industrial process, commercial, domestic and modern military applications of high-performance drive.

  5. An Algorithm for Glaucoma Screening in Clinical Settings and Its Preliminary Performance Profile

    Directory of Open Access Journals (Sweden)

    S-Farzad Mohammadi

    2013-01-01

    Full Text Available Purpose: To devise and evaluate a screening algorithm for glaucoma in clinical settings. Methods: Screening included examination of the optic disc for vertical cupping (≥0.4 and asymmetry (≥0.15, Goldmann applanation tonometry (≥21 mmHg, adjusted or unadjusted for central corneal thickness, and automated perimetry. In the diagnostic step, retinal nerve fiber layer imaging was performed using scanning laser polarimetry. Performance of the screening protocol was assessed in an eye hospital-based program in which 124 non-physician personnel aged 40 years or above were examined. A single ophthalmologist carried out the examinations and in equivocal cases, a glaucoma subspecialist′s opinion was sought. Results: Glaucoma was diagnosed in six cases (prevalence 4.8%; 95% confidence interval, 0.01-0.09 of whom five were new. The likelihood of making a definite diagnosis of glaucoma for those who were screened positively was 8.5 times higher than the estimated baseline risk for the reference population; the positive predictive value of the screening protocol was 30%. Screening excluded 80% of the initial population. Conclusion: Application of a formal screening protocol (such as our algorithm or its equivalent in clinical settings can be helpful in detecting new cases of glaucoma. Preliminary performance assessment of the algorithm showed its applicability and effectiveness in detecting glaucoma among subjects without any visual complaint.

  6. Preliminary Results of Performance Measurements on a Cylindrical Hall-Effect Thruster with Magnetic Field Generated by Permanent Magnets

    Science.gov (United States)

    Polzin, K. A.; Raitses, Y.; Merino, E.; Fisch, N. J.

    2008-01-01

    The performance of a low-power cylindrical Hall thruster, which more readily lends itself to miniaturization and low-power operation than a conventional (annular) Hall thruster, was measured using a planar plasma probe and a thrust stand. The field in the cylindrical thruster was produced using permanent magnets, promising a power reduction over previous cylindrical thruster iterations that employed electromagnets to generate the required magnetic field topology. Two sets of ring-shaped permanent magnets are used, and two different field configurations can be produced by reorienting the poles of one magnet relative to the other. A plasma probe measuring ion flux in the plume is used to estimate the current utilization for the two magnetic configurations. The measurements indicate that electron transport is impeded much more effectively in one configuration, implying a higher thrust efficiency. Preliminary thruster performance measurements on this configuration were obtained over a power range of 100-250 W. The thrust levels over this power range were 3.5-6.5 mN, with anode efficiencies and specific impulses spanning 14-19% and 875- 1425 s, respectively. The magnetic field in the thruster was lower for the thrust measurements than the plasma probe measurements due to heating and weakening of the permanent magnets, reducing the maximum field strength from 2 kG to roughly 750-800 G. The discharge current levels observed during thrust stand testing were anomalously high compared to those levels measured in previous experiments with this thruster.

  7. Preliminary Educational Specifications for the First Facility Fort Lincoln New Town Education System.

    Science.gov (United States)

    General Learning Corp., Washington, DC.

    These specifications are planned as guidelines for architects to design an educational facility that will be relevant to the needs of the Fort Lincoln community. It is important to understand that this document and architectural plans for the facility do coexist, and that the criteria presented here has played an important role in the actual…

  8. Myocardial late gadolinium enhancement in specific cardiomyopathies by cardiovascular magnetic resonance: a preliminary experience.

    Science.gov (United States)

    Silva, Caterina; Moon, James C; Elkington, Andrew G; John, Anna S; Mohiaddin, Raad H; Pennell, Dudley J

    2007-12-01

    Late gadolinium enhancement cardiovascular magnetic resonance (CMR) can visualize myocardial interstitial abnormalities. The aim of this study was to assess whether regions of abnormal myocardium can also be visualized by late enhancement gadolinium CMR in the specific cardiomyopathies. A retrospective review of all referrals for gadolinium CMR with specific cardiomyopathy over 20 months. Nine patients with different specific cardiomyopathies were identified. Late enhancement was demonstrated in all patients, with a mean signal intensity of 390 +/- 220% compared with normal regions. The distribution pattern of late enhancement was unlike the subendocardial late enhancement related to coronary territories found in myocardial infarction. The affected areas included papillary muscles (sarcoid), the mid-myocardium (Anderson-Fabry disease, glycogen storage disease, myocarditis, Becker muscular dystrophy) and the global sub-endocardium (systemic sclerosis, Loeffler's endocarditis, amyloid, Churg-Strauss). Focal myocardial late gadolinium enhancement is found in the specific cardiomyopathies, and the pattern is distinct from that seen in infarction. Further systematic studies are warranted to assess whether the pattern and extent of late enhancement may aid diagnosis and prognostic assessment.

  9. Duration specific Running performance in Elite Gaelic Football.

    Science.gov (United States)

    Malone, Shane; Solan, Barry; Hughes, Brian; Collins, Kieran

    2017-04-25

    The aim of the current investigation was to determine the position and duration specific running performance of elite Gaelic football players through the use of a moving average method. Global positioning system data (4-Hz, VX Sport, New-Zealand) were collected from thirty-five (n = 35) elite Gaelic football players across a two season period. A total of 32 competitive matches were analysed with 300 full match play data samples obtained for final analysis. Players were categorised based on positional groups; full-back, half-back, midfield, half- forward and full-forward. The velocity-time curve was analysed for each position using a rolling average method, where maximal values were calculated for ten different time durations (1-10 min) using total distance (m·min), high-speed (m·min) and sprint distance (m·min) across each match. There were large differences between the 1 and 2 min rolling averages and all other rolling average durations. Smaller differences were observed for rolling averages of a greater duration. Midfielders covered significantly more relative total, high speed and sprint distance than other positions across all time periods (p football fluctuates across match-play. These data provide further knowledge of the running requirements of Gaelic football competition and this information can be used to aide coaches and practitioners in adequately preparing athletes for the most demanding periods of play.

  10. High Performance Organ-Specific Nuclear Medicine Imagers.

    Science.gov (United States)

    Majewski, Stan

    2006-04-01

    One of the exciting applications of nuclear science is nuclear medicine. Well-known diagnostic imaging tools such as PET and SPECT (as well as MRI) were developed as spin-offs of basic scientific research in atomic and nuclear physics. Development of modern instrumentation for applications in particle physics experiments offers an opportunity to contribute to development of improved nuclear medicine (gamma and positron) imagers, complementing the present set of standard imaging tools (PET, SPECT, MRI, ultrasound, fMRI, MEG, etc). Several examples of new high performance imagers developed in national laboratories in collaboration with academia will be given to demonstrate this spin-off activity. These imagers are designed to specifically image organs such as breast, heart, head (brain), or prostate. The remaining and potentially most important challenging application field for dedicated nuclear medicine imagers is to assist with cancer radiation treatments. Better control of radiation dose delivery requires development of new compact in-situ imagers becoming integral parts of the radiation delivery systems using either external beams or based on radiation delivery by inserting or injecting radioactive sources (gamma, beta or alpha emitters) into tumors.

  11. Potential of preliminary test methods to predict biodegradation performance of petroleum hydrocarbons in soil.

    Science.gov (United States)

    Aichberger, H; Hasinger, Marion; Braun, Rudolf; Loibner, Andreas P

    2005-03-01

    Preliminary tests at different scales such as degradation experiments (laboratory) in shaking flasks, soil columns and lysimeters as well as in situ respiration tests (field) were performed with soil from two hydrocarbon contaminated sites. Tests have been evaluated in terms of their potential to provide information on feasibility, degradation rates and residual concentration of bioremediation in the vadose zone. Sample size, costs and duration increased with experimental scale in the order shaking flasks - soil columns - lysimeter - in situ respiration tests, only time demand of respiration tests was relatively low. First-order rate constants observed in degradation experiments exhibited significant differences between both, different experimental sizes and different soils. Rates were in line with type and history of contamination at the sites, but somewhat overestimated field rates particularly in small scale experiments. All laboratory experiments allowed an estimation of residual concentrations after remediation. In situ respiration tests were found to be an appropriate pre-testing and monitoring tool for bioventing although residual concentrations cannot be predicted from in situ respiration tests. Moreover, this method does not account for potential limitations that might hamper biodegradation in the longer term but only reflects the actual degradation potential when the test is performed.

  12. Cross-cultural effects on IQ test performance: a review and preliminary normative indications on WAIS-III test performance.

    Science.gov (United States)

    Shuttleworth-Edwards, Ann B; Kemp, Ryan D; Rust, Annegret L; Muirhead, Joanne G L; Hartman, Nigel P; Radloff, Sarah E

    2004-10-01

    This article presents a review of cross-cultural influences on Wechsler IQ tests, together with a preliminary investigation into WAIS-III test performance (English administration) for a southern African sample (age range 19-30) stratified for white English first language and black African first language, level and quality of education. ('African language' is the term used to denote the indigenous languages of black populations in southern Africa). A two-way ANOVA revealed highly significant effects for both level and quality of education within the black African first language group. Scores for the white English and black African first language groups with advantaged education were comparable with the US standardization, whereas scores for black African first language participants with disadvantaged education were significantly lower than this. Thus indications from this research are that normative studies should take account of the influential variable of quality of education, in addition to level of education. Alternatively faulty conclusions may be drawn about the effects of ethnicity, with the potential for neuropsychological misdiagnosis.

  13. Speech and Pause Characteristics in Multiple Sclerosis: A Preliminary Study of Speakers with High and Low Neuropsychological Test Performance

    Science.gov (United States)

    Feenaughty, Lynda; Tjaden, Kris; Benedict, Ralph H. B.; Weinstock-Guttman, Bianca

    2013-01-01

    This preliminary study investigated how cognitive-linguistic status in multiple sclerosis (MS) is reflected in two speech tasks (i.e. oral reading, narrative) that differ in cognitive-linguistic demand. Twenty individuals with MS were selected to comprise High and Low performance groups based on clinical tests of executive function and information…

  14. Cooling via one hand improves physical performance in heat-sensitive individuals with Multiple Sclerosis: A preliminary study

    Directory of Open Access Journals (Sweden)

    Murray Julie

    2008-05-01

    Full Text Available Abstract Background Many individuals afflicted with multiple sclerosis (MS experience a transient worsening of symptoms when body temperature increases due to ambient conditions or physical activity. Resulting symptom exacerbations can limit performance. We hypothesized that extraction of heat from the body through the subcutaneous retia venosa that underlie the palmar surfaces of the hands would reduce exercise-related heat stress and thereby increase the physical performance capacity of heat-sensitive individuals with MS. Methods Ten ambulatory MS patients completed one or more randomized paired trials of walking on a treadmill in a temperate environment with and without cooling. Stop criteria were symptom exacerbation and subjective fatigue. The cooling treatment entailed inserting one hand into a rigid chamber through an elastic sleeve that formed an airtight seal around the wrist. A small vacuum pump created a -40 mm Hg subatmospheric pressure enviinside the chamber where the palmar surface of the hand rested on a metal surface maintained at 18–22°C. During the treatment trials, the device was suspended from above the treadmill on a bungee cord so the subjects could comfortably keep a hand in the device without having to bear its weight while walking on the treadmill. Results When the trials were grouped by treatment only, cooling treatment increased exercise durations by 33% (43.6 ± 17.1 min with treatment vs. 32.8 ± 10.9 min. without treatment, mean ± SD, p -6, paired t-test, n = 26. When the average values were calculated for the subjects who performed multiple trials before the treatment group results were compared, cooling treatment increased exercise duration by 35% (42.8 ± 16.4 min with treatment vs. 31.7 ± 9.8 min. without treatment, mean ± SD, p Conclusion These preliminary results suggest that utilization of the heat transfer capacity of the non-hairy skin surfaces can enable temperature-sensitive individuals with MS to

  15. Performance adaptive training control strategy for recovering wrist movements in stroke patients: a preliminary, feasibility study

    Directory of Open Access Journals (Sweden)

    Sandini Giulio

    2009-12-01

    Full Text Available Abstract Background In the last two decades robot training in neuromotor rehabilitation was mainly focused on shoulder-elbow movements. Few devices were designed and clinically tested for training coordinated movements of the wrist, which are crucial for achieving even the basic level of motor competence that is necessary for carrying out ADLs (activities of daily life. Moreover, most systems of robot therapy use point-to-point reaching movements which tend to emphasize the pathological tendency of stroke patients to break down goal-directed movements into a number of jerky sub-movements. For this reason we designed a wrist robot with a range of motion comparable to that of normal subjects and implemented a self-adapting training protocol for tracking smoothly moving targets in order to facilitate the emergence of smoothness in the motor control patterns and maximize the recovery of the normal RoM (range of motion of the different DoFs (degrees of Freedom. Methods The IIT-wrist robot is a 3 DoFs light exoskeleton device, with direct-drive of each DoF and a human-like range of motion for Flexion/Extension (FE, Abduction/Adduction (AA and Pronation/Supination (PS. Subjects were asked to track a variable-frequency oscillating target using only one wrist DoF at time, in such a way to carry out a progressive splinting therapy. The RoM of each DoF was angularly scanned in a staircase-like fashion, from the "easier" to the "more difficult" angular position. An Adaptive Controller evaluated online performance parameters and modulated both the assistance and the difficulty of the task in order to facilitate smoother and more precise motor command patterns. Results Three stroke subjects volunteered to participate in a preliminary test session aimed at verify the acceptability of the device and the feasibility of the designed protocol. All of them were able to perform the required task. The wrist active RoM of motion was evaluated for each patient at the

  16. Preliminary Analysis of Effect of Random Segment Errors on Coronagraph Performance

    Science.gov (United States)

    Stahl, Mark T.; Shaklan, Stuart B.; Stahl, H. Philip

    2015-01-01

    Are we alone in the Universe is probably the most compelling science question of our generation. To answer it requires a large aperture telescope with extreme wavefront stability. To image and characterize Earth-like planets requires the ability to block 10(exp 10) of the host stars light with a 10(exp -11) stability. For an internal coronagraph, this requires correcting wavefront errors and keeping that correction stable to a few picometers rms for the duration of the science observation. This requirement places severe specifications upon the performance of the observatory, telescope and primary mirror. A key task of the AMTD project (initiated in FY12) is to define telescope level specifications traceable to science requirements and flow those specifications to the primary mirror. From a systems perspective, probably the most important question is: What is the telescope wavefront stability specification? Previously, we suggested this specification should be 10 picometers per 10 minutes; considered issues of how this specification relates to architecture, i.e. monolithic or segmented primary mirror; and asked whether it was better to have few or many segmented. This paper reviews the 10 picometers per 10 minutes specification; provides analysis related to the application of this specification to segmented apertures; and suggests that a 3 or 4 ring segmented aperture is more sensitive to segment rigid body motion that an aperture with fewer or more segments.

  17. Performance validation of commercially available mobile waste-assay systems: Preliminary report

    Energy Technology Data Exchange (ETDEWEB)

    Schanfein, M.; Bonner, C.; Maez, R. [Los Alamos National Lab., NM (United States)] [and others

    1997-11-01

    Prior to disposal, nuclear waste must be accurately characterized to identify and quantify the radioactive content to reduce the radioactive hazard to the public. Validation of the waste-assay systems` performance is critical for establishing the credibility of the assay results for storage and disposal purposes. Canberra Nuclear has evaluated regulations worldwide and identified standard, modular, neutron- and gamma-waste-assay systems that can be used to characterize a large portion of existing and newly generated transuranic (TRU) and low-level waste. Before making claims of guaranteeing any system`s performance for specific waste types, the standardized systems` performance be evaluated. 7 figs., 11 tabs.

  18. A Smart Insole to Promote Healthy Aging for Frail Elderly Individuals: Specifications, Design, and Preliminary Results

    OpenAIRE

    Piau, Antoine; Charlon, Yoann; Campo, Eric; Vellas, Bruno; Nourhashemi, Fati

    2015-01-01

    Background Older individuals frequently experience reversible ?frailty syndrome,?, increasing incidence of disability. Although physical exercise interventions may delay functional decline, there are difficulties in implementing them and performing seamless follow-up at home. Very few technological solutions attempt to address this challenge and improve individual participation. Objective Our objectives are to (1) develop a technological solution designed to support active aging of frail olde...

  19. Competitive Performance Correlates of Mental Toughness in Tennis: A Preliminary Analysis.

    Science.gov (United States)

    Cowden, Richard G

    2016-08-01

    This study investigated relationships between mental toughness and measures of competitive performance in tennis. Forty-three male (N = 25) and female (N = 18) players (M age = 13.6 years, SD = 2.4) completed the mental toughness inventory, and the point-by-point outcomes recorded during a competitive tennis match (singles) were used to generate performance indices for each athlete. The results indicated that mental toughness was associated with several, but not all, macro, micro, and critical moment performance indices. The findings suggest mental toughness may contribute to successful performance during tennis competition, although the importance of the construct appears to depend depend on specific match situations. Future mental toughness research should consider a range of factors related to sport performance, including athletes' and opponents' physical, technical, and tactical abilities.

  20. A Sensitivity Analysis of a Pipe Break Accident in a Preliminary Specific Design of the PGSFR

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Kwi Lim; Jeong, Jae Ho; Ha, Kwi Seok [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2015-05-15

    The PGSFR (Prototype Gen-IV Sodium-cooled Fast Reactor) is a pool type sodium cooled fast reactor with a thermal power of 392.1 MW which has been developed in accord with an enhanced safety, an efficient utilization of uranium resources and a reduction of a high level waste volume in the Korea Atomic Energy Research Institute (KAERI) since 2012 under a National Nuclear R and D Program. The PGSFR has an inherent safety characteristic owing to the design to have a negative power reactivity coefficient during all operation modes and it has a passive safety characteristic due to the design of a passive decay heat removal circuit. In order to assess the inherent safety features of the PGSFR, a safety analysis was performed for a pipe break accident with MARS-LMR. And, the sensitivity studies were also performed to find the most conservative condition. As a result, the PGSFR was appropriately tripped by a high power to PHTS flow ratio using the method of extracting the PHTS flow rate from the pressure drop. The air flow rate was the most sensitive variable in the sensitivity analysis. Therefore, it is important to know the accurate uncertainty of the air flow rate in the AHX.

  1. Set-up and preliminary performance of a digital radiology conference system

    Institute of Scientific and Technical Information of China (English)

    王学建; 胡建; 曹军; 王波; 焦俊; 魏渝清; 王小林; 罗敏; 罗松

    2003-01-01

    Objective To investigate the set-up and preliminary performance of a digital radiology conference system and its characteristics. Methods The imaging system included a dual-screen image-text workstation with a Matrox G450 demonstration dual-head card, two multimedia projectors, a large screen, and a line-pair and grey scale test card. Patient information on radiology information system (RIS) and images on picture archiving and communication system (PACS) were fetched with GE Radworks software based on Intranet and PACS. The fetching velocity and resolution and grey scale of the images were measured. Results Patient information in the form of texts and images were demonstrated successfully on two screens with Matrox G450 demonstration dual-head card and switched rapidly between text-image two-screen and image two-screen. The image fetching velocity was fast, the resolution was high, and the grey scale was good. Conclusion The digital conference radiology system is good, and should be popularized.

  2. A smartphone-based platform to test the performance of wireless mobile networks and preliminary findings

    Science.gov (United States)

    Geng, Xinli; Xu, Hao; Qin, Xiaowei

    2016-10-01

    During the last several years, the amount of wireless network traffic data increased fast and relative technologies evolved rapidly. In order to improve the performance and Quality of Experience (QoE) of wireless network services, the analysis of field network data and existing delivery mechanisms comes to be a promising research topic. In order to achieve this goal, a smartphone based platform named Monitor and Diagnosis of Mobile Applications (MDMA) was developed to collect field data. Based on this tool, the web browsing service of High Speed Downlink Packet Access (HSDPA) network was tested. The top 200 popular websites in China were selected and loaded on smartphone for thousands times automatically. Communication packets between the smartphone and the cell station were captured for various scenarios (e.g. residential area, urban roads, bus station etc.) in the selected city. A cross-layer database was constructed to support the off-line analysis. Based on the results of client-side experiments and analysis, the usability of proposed portable tool was verified. The preliminary findings and results for existing web browsing service were also presented.

  3. General strategies to set quality specifications for reliability performance characteristics.

    Science.gov (United States)

    Fraser, C G

    1999-11-01

    Many strategies have been promulgated for the setting of quality specifications in laboratory medicine. Based on the analysis of the effect of error on clinical decision making, general quality specifications for precision, bias, the allowable difference between two analytical methods, drugs, fixed limits for use in external quality assessment and reference methods seem best derived from components of biological variation.

  4. Preliminary observation of genes specifically expressed in brain tissues during stroke-like episodes in rats

    Institute of Scientific and Technical Information of China (English)

    WANG Xian-mei; ZHAO Bin; ZHU Shan-jun; ZHU Zhi-ming; ZHANG Qian; HUI Ru-tai

    2001-01-01

    Objective: To observe the difference of gene expressions of brain tissues during apoplectic episodes and those of normal brain in Wistar rats in order to study the pathological mechanism of apoplexy. Methods: A rat model of hypertension was established with the administration of cold stimulus and high salt intake as the environmental risk factors.Apoplexy occurred in the rats because of hypertension. Suppression subtractive hybridization(SSH) was used to identify and analyze the differential genes specifically expressed in cerebral tissues of stoke group and control rats. Results: A total of 226 genes out of the 228 were usable and analyzed. The average length of the 226 genes was (286.6±120.3) bp with a range from 50 bp to 619 bp. And 126 clones out of the 226 showed a sequence with significant identity to the known genes; 78 clones demonstrated homogenous sequences to the existing ESTs ofdbEST, but no one of the 78 showed sequence with identity to that of known genes; and remaining 22 were novel transrcipts exhibiting no similarity to any known sequences. All the clones which were highly homogenous to the known genes were categorized on the basis of their function. It was found that 26.5% of the mitochodrial genes in brain tissues underwent changes after apoplexy and the changes showed a twofold relationship of cause and effect. Conclusion: Environmental factors are able to induce changes of gene expression, which may increase the sensitivity to apoplectic stroke.

  5. Preliminary trial of augmented reality performed on a laparoscopic left hepatectomy.

    Science.gov (United States)

    Phutane, Priyanka; Buc, Emmanuel; Poirot, Karine; Ozgur, Erol; Pezet, Denis; Bartoli, Adrien; Le Roy, Bertrand

    2017-08-08

    Laparoscopic liver surgery is seldom performed, mainly because of the risk of hepatic vein bleeding or incomplete resection of the tumour. This risk may be reduced by means of an augmented reality guidance system (ARGS), which have the potential to aid one in finding the position of intrahepatic tumours and hepatic veins and thus in facilitating the oncological resection and in limiting the risk of operative bleeding. We report the case of an 81-year-old man who was diagnosed with a hepatocellular carcinoma after an intraabdominal bleeding. The preoperative CT scan did not show metastases. We describe our preferred approach for laparoscopic left hepatectomy with initial control of the left hepatic vein and preliminary results of our novel ARGS achieved postoperatively. In our ARGS, a 3D virtual anatomical model is created from the abdominal CT scan and manually registered to selected laparoscopic images. For this patient, the virtual model was composed of the segmented left liver, right liver, tumour and median hepatic vein. The patient's operating time was summed up to 205 min where a blood loss of 300 cc was recorded. The postoperative course was simple. Histopathological analysis revealed the presence of a hepatocellular carcinoma with free margins. Our results of intrahepatic visualization suggest that ARGS can be beneficial in detecting the tumour, transection plane and medial hepatic vein prior to parenchymal transection, where it does not work due to the substantial changes to the liver's shape. As of today, we have performed eight similar left hepatectomies, with good results. Our ARGS has shown promising results and should now be attempted intraoperatively.

  6. Site-specific, adult bone benefits attributed to loading during youth: A preliminary longitudinal analysis.

    Science.gov (United States)

    Scerpella, Tamara A; Bernardoni, Brittney; Wang, Sijian; Rathouz, Paul J; Li, Quefeng; Dowthwaite, Jodi N

    2016-04-01

    We examined site-specific bone development in relation to childhood and adolescent artistic gymnastics exposure, comparing up to 10years of prospectively acquired longitudinal data in 44 subjects, including 31 non-gymnasts (NON) and 13 gymnasts (GYM) who participated in gymnastics from pre-menarche to ≥1.9years post-menarche. Subjects underwent annual regional and whole-body DXA scans; indices of bone geometry and strength were calculated. Anthropometrics, physical activity, and maturity were assessed annually, coincident with DXA scans. Non-linear mixed effect models centered growth in bone outcomes at menarche and adjusted for menarcheal age, height, and non-bone fat-free mass to evaluate GYM-NON differences. A POST-QUIT variable assessed the withdrawal effect of quitting gymnastics. Curves for bone area, mass (BMC), and strength indices were higher in GYM than NON at both distal radius metaphysis and diaphysis (pGYM BMC (pGYM endosteal diameter (pGYM advantages in narrow neck cortical thickness and buckling ratio (both pGYM than NON (pGYM slopes increased for distal radius diaphysis parameters (p≤0.01) and for narrow neck BR (p=0.02). At the distal radius metaphysis, GYM BMC and compressive strength slopes decreased, as did slopes for lumbar spine BMC, femoral neck BMC, and narrow neck cortical thickness (p<0.02). In conclusion, advantages in bone mass, geometry, and strength at multiple skeletal sites were noted across growth and into young adulthood in girls who participated in gymnastics loading to at least 1.9years post-menarche. Following gymnastics cessation, advantages at cortical bone sites improved or stabilized, while advantages at corticocancellous sites stabilized or diminished. Additional longitudinal observation is necessary to determine whether residual loading benefits enhance lifelong skeletal strength.

  7. Parametric Fuselage Geometry Generation and Aerodynamic Performance Prediction in Preliminary Rotorcraft Design

    OpenAIRE

    Kunze, Philipp

    2013-01-01

    The creation of an integrated rotorcraft conceptual and preliminary design framework at DLR involved the development of geometry and fuselage aerodynamics modules at the Institute of Aerodynamics and Flow Technology. After a short revision of the RIDE rotorcraft design environment architecture this paper focuses on the implementation of these disciplinary modules. The aim of the geometry module is to bridge the gap between conceptual and preliminary design and to allow for geometry parameter ...

  8. Preliminary Assessment of Variable Speed Power Turbine Technology on Civil Tiltrotor Size and Performance

    Science.gov (United States)

    Snyder, Christopher A.; Acree, Cecil W., Jr.

    2012-01-01

    A Large Civil Tiltrotor (LCTR) conceptual design was developed as part of the NASA Heavy Lift Rotorcraft Systems Investigation in order to establish a consistent basis for evaluating the benefits of advanced technology for large tiltrotors. The concept has since evolved into the second-generation LCTR2, designed to carry 90 passengers for 1,000 nm at 300 knots, with vertical takeoff and landing capability. This paper performs a preliminary assessment of variable-speed power turbine technology on LCTR2 sizing, while maintaining the same, advanced technology engine core. Six concepts were studied; an advanced, single-speed engine with a conventional power turbine layout (Advanced Conventional Engine, or ACE) using a multi-speed (shifting) gearbox. There were five variable-speed power turbine (VSPT) engine concepts, comprising a matrix of either three or four turbine stages, and fixed or variable guide vanes; plus a minimum weight, twostage, fixed-geometry VSPT. The ACE is the lightest engine, but requires a multi-speed (shifting) gearbox to maximize its fuel efficiency, whereas the VSPT concepts use a lighter, fixed-ratio gearbox. The NASA Design and Analysis of Rotorcraft (NDARC) design code was used to study the trades between rotor and engine efficiency and weight. Rotor performance was determined by Comprehensive Analytical Model of Rotorcraft Aerodynamics and Dynamics (CAMRAD II), and engine performance was estimated with the Numerical Propulsion System Simulation (NPSS). Design trades for the ACE vs. VSPT are presented in terms of vehicle gross and empty weight, propulsion system weight and mission fuel burn for the civil mission. Because of its strong effect on gearbox weight and on both rotor and engine efficiency, rotor speed was chosen as the reference design variable for comparing design trades. Major study assumptions are presented and discussed. Impressive engine power-to-weight and fuel efficiency reduced vehicle sensitivity to propulsion system choice

  9. 40 CFR Appendix B to Part 60 - Performance Specifications

    Science.gov (United States)

    2010-07-01

    ... instrumental measurement of opacity caused by attenuation of projected light due to absorption and scatter of... continual compliance with an emission limit than those used to measure excess emissions. You must perform... Emissions PEMS. For a PEMS that is used for excess emission reporting, the owner or operator must perform...

  10. Physiological and Biomechanical Mechanisms of Distance Specific Human Running Performance.

    Science.gov (United States)

    Thompson, M A

    2017-08-01

    Running events range from 60-m sprints to ultra-marathons covering 100 miles or more, which presents an interesting diversity in terms of the parameters for successful performance. Here, we review the physiological and biomechanical variations underlying elite human running performance in sprint to ultramarathon distances. Maximal running speeds observed in sprint disciplines are achieved by high vertical ground reaction forces applied over short contact times. To create this high force output, sprint events rely heavily on anaerobic metabolism, as well as a high number and large cross-sectional area of type II fibers in the leg muscles. Middle distance running performance is characterized by intermediates of biomechanical and physiological parameters, with the possibility of unique combinations of each leading to high-level performance. The relatively fast velocities in mid-distance events require a high mechanical power output, though ground reaction forces are less than in sprinting. Elite mid-distance runners exhibit local muscle adaptations that, along with a large anaerobic capacity, provide the ability to generate a high power output. Aerobic capacity starts to become an important aspect of performance in middle distance events, especially as distance increases. In distance running events, V˙O2max is an important determinant of performance, but is relatively homogeneous in elite runners. V˙O2 and velocity at lactate threshold have been shown to be superior predictors of elite distance running performance. Ultramarathons are relatively new running events, as such, less is known about physiological and biomechanical parameters that underlie ultra-marathon performance. However, it is clear that performance in these events is related to aerobic capacity, fuel utilization, and fatigue resistance. Published by Oxford University Press on behalf of the Society for Integrative and Comparative Biology 2017. This work is written by US Government employees and is in

  11. SYSTEM PERFORMANCE SPECIFICATION FOR A NATIONAL CHEMICAL INFORMATION SYSTEM.

    Science.gov (United States)

    Information Management, Inc., Burlington, MA.

    THIS DOCUMENT CONTAINS A SET OF STATEMENTS ABOUT INFORMATION NEEDS, SYSTEM GOALS, SYSTEM REQUIREMENTS, AND SYSTEM SPECIFICATIONS FOR THE DEVELOPMENT OF A NATIONAL CHEMICAL INFORMATION SYSTEM. IN ITS PRESENT FORM, THE DOCUMENT CONSTITUTES A BASIS FOR FUTURE PLANNING. AS POLICY DECISIONS ARE MADE, TECHNICAL PROBLEMS SOLVED AND PLANS ARE ALTERED, THE…

  12. LOD 1 VS. LOD 2 - Preliminary Investigations Into Differences in Mobile Rendering Performance

    Science.gov (United States)

    Ellul, C.; Altenbuchner, J.

    2013-09-01

    The increasing availability, size and detail of 3D City Model datasets has led to a challenge when rendering such data on mobile devices. Understanding the limitations to the usability of such models on these devices is particularly important given the broadening range of applications - such as pollution or noise modelling, tourism, planning, solar potential - for which these datasets and resulting visualisations can be utilized. Much 3D City Model data is created by extrusion of 2D topographic datasets, resulting in what is known as Level of Detail (LoD) 1 buildings - with flat roofs. However, in the UK the National Mapping Agency (the Ordnance Survey, OS) is now releasing test datasets to Level of Detail (LoD) 2 - i.e. including roof structures. These datasets are designed to integrate with the LoD 1 datasets provided by the OS, and provide additional detail in particular on larger buildings and in town centres. The availability of such integrated datasets at two different Levels of Detail permits investigation into the impact of the additional roof structures (and hence the display of a more realistic 3D City Model) on rendering performance on a mobile device. This paper describes preliminary work carried out to investigate this issue, for the test area of the city of Sheffield (in the UK Midlands). The data is stored in a 3D spatial database as triangles and then extracted and served as a web-based data stream which is queried by an App developed on the mobile device (using the Android environment, Java and OpenGL for graphics). Initial tests have been carried out on two dataset sizes, for the city centre and a larger area, rendering the data onto a tablet to compare results. Results of 52 seconds for rendering LoD 1 data, and 72 seconds for LoD 1 mixed with LoD 2 data, show that the impact of LoD 2 is significant.

  13. Preliminary evaluation of the air and fuel specific-impulse characteristics of several potential ram-jet fuels IV : hydrogen, a-methylnaphthalene, and carbon / Benson E. Gammon

    Science.gov (United States)

    Gammon, Benson E

    1951-01-01

    A preliminary analytical evaluation of the air and fuel specific-impulse characteristics of hydrogen, a-methylnapthalene, and graphite carbon has been made. Adiabatic constant-pressure combustion flame temperatures for each fuel at several equivalence ratios were calculated for an initial air temperature of 560 degrees R and a pressure of 2 atmospheres.

  14. A climate and environmental context for hominid evolution: Preliminary biomarker and compound specific isotope data from Lake Magadi, Kenya

    Science.gov (United States)

    Werne, J. P.; Ferland, T.; Cohen, A. S.; Lowenstein, T. K.; Deocampo, D.; Renaut, R.; Bernhart, O. R.

    2016-12-01

    The Hominid Sites and Paleolakes Drilling Project (HSPDP) seeks to understand the paleoclimatic and paleoenvironmental context of human evolution and development by analysis of paleolacustrine cores taken near key hominin fossil and artifact localities in Kenya and Ethiopia. Here, we present biomarker and compound specific isotope data from a 200 m drill core from Lake Magadi, Kenya. Located 20 km from the Koora Plain in the southern Kenya Rift, and adjacent to the Olorgesailie basin, Lake Magadi is in one of the richest Early-Late Pleistocene archaeological localities in Africa, a region that has been key in debates about the relationship between climate and evolution. Preliminary biomarker work has shown promising abundances of leaf waxes, whose isotopic compositions of hydrogen and carbon are commonly used as proxies for paleoprecipitation and watershed vegetation composition, respectively. A complementary record of glycerol dialkyl glycerol tetraethers (GDGTs), which can serve as a proxy for temperature, soil input, and/or pH, will be presented alongside the leaf wax data to enhance the paleoenvironmental reconstruction of Lake Magadi. Present-day Lake Magadi is a saline pan, a descendant of a series of paleolakes that have occupied its drainage basin for approximately one million years. Hominid evolution milestones such as the mastering of fire as a tool, rapid encephalization, and the emergence of Homo sapiens all are thought to have occurred in the time frame encompassed by our record.

  15. Subject-specific estimation of central aortic blood pressure via system identification: preliminary in-human experimental study.

    Science.gov (United States)

    Fazeli, Nima; Kim, Chang-Sei; Rashedi, Mohammad; Chappell, Alyssa; Wang, Shaohua; MacArthur, Roderick; McMurtry, M Sean; Finegan, Barry; Hahn, Jin-Oh

    2014-10-01

    This paper demonstrates preliminary in-human validity of a novel subject-specific approach to estimation of central aortic blood pressure (CABP) from peripheral circulatory waveforms. In this "Individualized Transfer Function" (ITF) approach, CABP is estimated in two steps. First, the circulatory dynamics of the cardiovascular system are determined via model-based system identification, in which an arterial tree model is characterized based on the circulatory waveform signals measured at the body's extremity locations. Second, CABP waveform is estimated by de-convolving peripheral circulatory waveforms from the arterial tree model. The validity of the ITF approach was demonstrated using experimental data collected from 13 cardiac surgery patients. Compared with the invasive peripheral blood pressure (BP) measurements, the ITF approach yielded significant reduction in errors associated with the estimation of CABP, including 1.9-2.6 mmHg (34-42 %) reduction in BP waveform errors (p < 0.05) as well as 5.8-9.1 mmHg (67-76 %) and 6.0-9.7 mmHg (78-85 %) reductions in systolic and pulse pressure (SP and PP) errors (p < 0.05). It also showed modest but significant improvement over the generalized transfer function approach, including 0.1 mmHg (2.6 %) reduction in BP waveform errors as well as 0.7 (20 %) and 5.0 mmHg (75 %) reductions in SP and PP errors (p < 0.05).

  16. [Dance, art and top performance sport with specific injuries].

    Science.gov (United States)

    Rietveld, Boni; van de Wiel, Albert

    2011-01-01

    Professional theatre dance has high and specific physical demands, comparable to top sport. Dance injuries are often caused by faulty technique due to compensation for physical limitations. Knowledge of these limitations and professional teaching can prevent many problems. Dance injuries mostly involve the lower limbs, especially the ankles and knees. Dance injuries require that the medical professional has knowledge of dance technique and respects the passion of the dancer. The advice to stop dancing has hardly ever to be given. Scientific, prospective dance medical research is recommended.

  17. 14 CFR 91.705 - Operations within airspace designated as Minimum Navigation Performance Specification Airspace.

    Science.gov (United States)

    2010-01-01

    ... Minimum Navigation Performance Specification Airspace. 91.705 Section 91.705 Aeronautics and Space FEDERAL... Operations within airspace designated as Minimum Navigation Performance Specification Airspace. (a) Except as... airspace designated as Minimum Navigation Performance Specifications airspace unless— (1) The aircraft...

  18. Tactic-specific differences in seminal fluid influence sperm performance.

    Science.gov (United States)

    Locatello, Lisa; Poli, Federica; Rasotto, Maria B

    2013-03-22

    Seminal fluid often makes up a large part of an ejaculate, yet most empirical and theoretical studies on sperm competition have focused on how sperm characteristics (number and quality) affect fertilization success. However, seminal fluid influences own sperm performance and may potentially influence the outcome of sperm competition, by also affecting that of rivals. As a consequence males may be expected to allocate their investment in both sperm and seminal fluid in relation to the potential level of competition. Grass goby (Zosterisessor ophiocephalus) is an external fertilizer with guard-sneaker mating tactics, where sperm competition risk varies according to the tactic adopted. Here, we experimentally manipulated grass goby ejaculates by separately combining sperm and seminal fluid from territorial and sneaker males. While sperm of sneaker and territorial males did not differ in their performance when they interacted with their own seminal fluid only, sperm of sneakers increased their velocity and fertilization rate in the presence of territorial males' seminal fluid. By contrast, sneaker males' seminal fluid had a detrimental effect on the performance of territorial males' sperm. Sperm velocity was unaffected by the seminal fluid of males employing the same tactic, suggesting that seminal fluid's effect on rival-tactic sperm is not based on a self/non-self recognition mechanism. Our findings show that cross interactions of sperm and seminal fluid may influence the fertilization success of competing ejaculates with males investing in both sperm and seminal fluid in response to sperm competition risk.

  19. Respiratory muscle specific warm-up and elite swimming performance.

    Science.gov (United States)

    Wilson, Emma E; McKeever, Tricia M; Lobb, Claire; Sherriff, Tom; Gupta, Luke; Hearson, Glenn; Martin, Neil; Lindley, Martin R; Shaw, Dominick E

    2014-05-01

    Inspiratory muscle training has been shown to improve performance in elite swimmers, when used as part of routine training, but its use as a respiratory warm-up has yet to be investigated. To determine the influence of inspiratory muscle exercise (IME) as a respiratory muscle warm-up in a randomised controlled cross-over trial. A total of 15 elite swimmers were assigned to four different warm-up protocols and the effects of IME on 100 m freestyle swimming times were assessed.Each swimmer completed four different IME warm-up protocols across four separate study visits: swimming-only warm-up; swimming warm-up plus IME warm-up (2 sets of 30 breaths with a 40% maximum inspiratory mouth pressure load using the Powerbreathe inspiratory muscle trainer); swimming warm-up plus sham IME warm-up (2 sets of 30 breaths with a 15% maximum inspiratory mouth pressure load using the Powerbreathe inspiratory muscle trainer); and IME-only warm-up. Swimmers performed a series of physiological tests and scales of perception (rate of perceived exertion and dyspnoea) at three time points (pre warm-up, post warm-up and post time trial). The combined standard swimming warm-up and IME warm-up were the fastest of the four protocols with a 100 m time of 57.05 s. This was significantly faster than the IME-only warm-up (mean difference=1.18 s, 95% CI 0.44 to 1.92, pswim-only warm-up (mean difference=0.62 s, 95% CI 0.001 to 1.23, p=0.05). Using IME combined with a standard swimming warm-up significantly improves 100 m freestyle swimming performance in elite swimmers.

  20. Respiratory muscle specific warm-up and elite swimming performance

    OpenAIRE

    Wilson, Emma Elizabeth; Mckeever, Tricia M; Lobb, Claire; Sherriff, Tom; Gupta, Luke; Hearson, Glenn; Martin, Neil; Lindley, Martin R.; Shaw, Dominick E.

    2014-01-01

    Background: Inspiratory muscle training has been shown to improve performance in elite swimmers, when used as part of routine training, but its use as a respiratory warm-up has yet to be investigated. Aim: To determine the influence of inspiratory muscle exercise (IME) as a respiratory muscle warm-up in a randomised controlled cross-over trial. Methods: A total of 15 elite swimmers were assigned to four different warm-up protocols and the effects of IME on 100 m freestyle swimming times...

  1. Respiratory muscle specific warm-up and elite swimming performance

    OpenAIRE

    Wilson, Emma Elizabeth; Mckeever, Tricia M; Lobb, Claire; Sherriff, Tom; Gupta, Luke; Hearson, Glenn; Martin, Neil; Lindley, Martin R.; Shaw, Dominick E.

    2014-01-01

    Background: Inspiratory muscle training has been shown to improve performance in elite swimmers, when used as part of routine training, but its use as a respiratory warm-up has yet to be investigated.\\ud Aim: To determine the influence of inspiratory muscle exercise (IME) as a respiratory muscle warm-up in a randomised controlled cross-over trial.\\ud Methods: A total of 15 elite swimmers were assigned to four different warm-up protocols and the effects of IME on 100 m freestyle swimming times...

  2. Preliminary Study of MALDI-TOF Mass Spectrometry-based Screening of Patients with the NSCLC Serum-Specific Peptides

    Directory of Open Access Journals (Sweden)

    Juan AN

    2013-05-01

    Full Text Available Background and objective The improved survival of patients with lung cancer depends on early diagnosis of lung cancer. However, the traditional diagnostic techniques have several limitations. Mass spectrometry (MS has been applied as a core technology for cancer diagnosis in preliminary proteomic studies. The aim of this study is to explore the differences in the serum peptide levels of patients with non-small cell lung cancer (NSCLC and healthy individuals using matrix-assisted laser desorption/ionization (MALDI-time-of-flight (TOF-MS. A NSCLC serum classification model was then established. Methods One hundred and thirty three cases of patients with NSCLC serum specimens and 132 cases of healthy human serum specimens were randomly divided into two groups in accordance with the ratio of three to one without age and gender differences. The training group was used to establish the classification model, this group included serum samples from 100 NSCLC cases and 100 healthy individuals. The test group for validating the proposed model was composed of the remaining serum samples from 33 NSCLC cases and 32 healthy individuals. Peptides were extracted from the samples using magnetic beads- immobilized metal affinity capture - copper, and their mass spectra were obtained using an automated MALDI-TOF-MS system. The MS data from the training group was analyzed using the ClinproToolTM software to identify the individual peptide fragments and establish the classification model. The sensitivity and specificity of the model were verified by blind testing with the test group. Results Among the 131 different peptide peaks, ranging from m/z 1,000 Da to 10,000 Da, 14 peaks were significantly different in the NSCLC samples of the training group, as compared with the controls (P<0.000,001; AUC≥0.9; these included 2 higher peaks and 12 lower peaks. The classification model was established, and the test group was verified for only 3 peptide peaks (7,478.59, 2

  3. High Performance Computing - Power Application Programming Interface Specification.

    Energy Technology Data Exchange (ETDEWEB)

    Laros, James H.,; Kelly, Suzanne M.; Pedretti, Kevin; Grant, Ryan; Olivier, Stephen Lecler; Levenhagen, Michael J.; DeBonis, David

    2014-08-01

    Measuring and controlling the power and energy consumption of high performance computing systems by various components in the software stack is an active research area [13, 3, 5, 10, 4, 21, 19, 16, 7, 17, 20, 18, 11, 1, 6, 14, 12]. Implementations in lower level software layers are beginning to emerge in some production systems, which is very welcome. To be most effective, a portable interface to measurement and control features would significantly facilitate participation by all levels of the software stack. We present a proposal for a standard power Application Programming Interface (API) that endeavors to cover the entire software space, from generic hardware interfaces to the input from the computer facility manager.

  4. Task-specific performance effects with different numeric keypad layouts.

    Science.gov (United States)

    Armand, Jenny T; Redick, Thomas S; Poulsen, Joan R

    2014-07-01

    Two commonly used keypad arrangements are the telephone and calculator layouts. The purpose of this study was to determine if entering different types of numeric information was quicker and more accurate with the telephone or the calculator layout on a computer keyboard numeric keypad. Fifty-seven participants saw a 10-digit numeric stimulus to type with a computer number keypad as quickly and as accurately as possible. Stimuli were presented in either a numerical [1,234,567,890] or phone [(123) 456-7890] format. The results indicated that participants' memory of the layout for the arrangement of keys on a telephone was significantly better than the layout of a calculator. In addition, the results showed that participants were more accurate when entering stimuli using the calculator keypad layout. Critically, participants' response times showed an interaction of stimulus format and keypad layout: participants were specifically slowed when entering numeric stimuli using a telephone keypad layout. Responses made using the middle row of keys were faster and more accurate than responses using the top and bottom row of keys. Implications for keypad design and cell phone usage are discussed.

  5. Evaluation of the diagnostic performance of infrared imaging of the breast: a preliminary study

    Directory of Open Access Journals (Sweden)

    Wu Yuh-Ming

    2010-01-01

    Full Text Available Abstract Background The study was conducted to investigate the diagnostic performance of infrared (IR imaging of the breast using an interpretive model derived from a scoring system. Methods The study was approved by the Institutional Review Board of our hospital. A total of 276 women (mean age = 50.8 years, SD 11.8 with suspicious findings on mammograms or ultrasound received IR imaging of the breast before excisional biopsy. The interpreting radiologists scored the lesions using a scoring system that combines five IR signs. The ROC (receiver operating characteristic curve and AUC (area under the ROC curve were analyzed by the univariate logistic regression model for each IR sign and an age-adjusted multivariate logistic regression model including 5 IR signs. The cut-off values and corresponding sensitivity, specificity, Youden's Index (Index = sensitivity+specificity-1, positive predictive value (PPV, negative predictive value (NPV were estimated from the age-adjusted multivariate model. The most optimal cut-off value was determined by the one with highest Youden's Index. Results For the univariate model, the AUC of the ROC curve from five IR signs ranged from 0.557 to 0.701, and the AUC of the ROC from the age-adjusted multivariate model was 0.828. From the ROC derived from the multivariate model, the sensitivity of the most optimal cut-off value would be 72.4% with the corresponding specificity 76.6% (Youden's Index = 0.49, PPV 81.3% and NPV 66.4%. Conclusions We established an interpretive age-adjusted multivariate model for IR imaging of the breast. The cut-off values and the corresponding sensitivity and specificity can be inferred from the model in a subpopulation for diagnostic purpose. Trial Registration NCT00166998.

  6. Global atmospheric response to specific linear combinations of the main SST modes.. Part I: numerical experiments and preliminary results

    Science.gov (United States)

    Trzaska, S.; Moron, V.; Fontaine, B.

    1996-10-01

    This article investigates through numerical experiments the controversial question of the impact of El Niño-Southern Oscillation (ENSO) phenomena on climate according to large-scale and regional-scale interhemispheric thermal contrast. Eight experiments (two considering only inversed Atlantic thermal anomalies and six combining ENSO warm phase with large-scale interhemispheric contrast and Atlantic anomaly patterns) were performed with the Météo-France atmospheric general circulation model. The definition of boundary conditions from observed composites and principal components is presented and preliminary results concerning the month of August, especially over West Africa and the equatorial Atlantic are discussed. Results are coherent with observations and show that interhemispheric and regional scale sea-surface-temperature anomaly (SST) patterns could significantly modulate the impact of ENSO phenomena: the impact of warm-phase ENSO, relative to the atmospheric model intercomparison project (AMIP) climatology, seems stronger when embedded in global and regional SSTA patterns representative of the post-1970 conditions [i.e. with temperatures warmer (colder) than the long-term mean in the southern hemisphere (northern hemisphere)]. Atlantic SSTAs may also play a significant role. Acknowledgements. We gratefully appreciate the on-line DMSP database facility at APL (Newell et al., 1991) from which this study has benefited greatly. We wish to thank E. Friis-Christensen for his encouragement and useful discussions. A. Y. would like to thank the Danish Meteorological Institute, where this work was done, for its hospitality during his stay there and the Nordic Baltic Scholarship Scheme for its financial support of this stay. Topical Editor K.-H. Glassmeier thanks M. J. Engebretson and H. Lühr for their help in evaluating this paper.--> Correspondence to: A. Yahnin-->

  7. Cognitive predictors of skilled performance with an advanced upper limb multifunction prosthesis: a preliminary analysis.

    Science.gov (United States)

    Hancock, Laura; Correia, Stephen; Ahern, David; Barredo, Jennifer; Resnik, Linda

    2016-04-06

    Purpose The objectives were to 1) identify major cognitive domains involved in learning to use the DEKA Arm; 2) specify cognitive domain-specific skills associated with basic versus advanced users; and 3) examine whether baseline memory and executive function predicted learning. Method Sample included 35 persons with upper limb amputation. Subjects were administered a brief neuropsychological test battery prior to start of DEKA Arm training, as well as physical performance measures at the onset of, and following training. Multiple regression models controlling for age and including neuropsychological tests were developed to predict physical performance scores. Prosthetic performance scores were divided into quartiles and independent samples t-tests compared neuropsychological test scores of advanced scorers and basic scorers. Baseline neuropsychological test scores were used to predict change in scores on physical performance measures across time. Results Cognitive domains of attention and processing speed were statistically significantly related to proficiency of DEKA Arm use and predicted level of proficiency. Conclusions Results support use of neuropsychological tests to predict learning and use of a multifunctional prosthesis. Assessment of cognitive status at the outset of training may help set expectations for the duration and outcomes of treatment. Implications for Rehabilitation Cognitive domains of attention and processing speed were significantly related to level of proficiencyof an advanced multifunctional prosthesis (the DEKA Arm) after training. Results provide initial support for the use of neuropsychological tests to predict advanced learningand use of a multifunctional prosthesis in upper-limb amputees. Results suggest that assessment of patients' cognitive status at the outset of upper limb prosthetictraining may, in the future, help patients, their families and therapists set expectations for theduration and intensity of training and may help set

  8. Preliminary results on performance testing of a turbocharged rotary combustion engine

    Science.gov (United States)

    Meng, P. R.; Rice, W. J.; Schock, H. J.; Pringle, D. P.

    1982-01-01

    The performance of a turbocharged rotary engine at power levels above 75 kW (100 hp) was studied. A twin rotor turbocharged Mazda engine was tested at speeds of 3000 to 6000 rpm and boost pressures to 7 psi. The NASA developed combustion diagnostic instrumentation was used to quantify indicated and pumping mean effect pressures, peak pressure, and face to face variability on a cycle by cycle basis. Results of this testing showed that a 5900 rpm a 36 percent increase in power was obtained by operating the engine in the turbocharged configuration. When operating with lean carburetor jets at 105 hp (78.3 kW) and 4000 rpm, a brake specific fuel consumption of 0.45 lbm/lb-hr was measured.

  9. Preliminary Axial Flow Turbine Design and Off-Design Performance Analysis Methods for Rotary Wing Aircraft Engines. Part 1; Validation

    Science.gov (United States)

    Chen, Shu-cheng, S.

    2009-01-01

    For the preliminary design and the off-design performance analysis of axial flow turbines, a pair of intermediate level-of-fidelity computer codes, TD2-2 (design; reference 1) and AXOD (off-design; reference 2), are being evaluated for use in turbine design and performance prediction of the modern high performance aircraft engines. TD2-2 employs a streamline curvature method for design, while AXOD approaches the flow analysis with an equal radius-height domain decomposition strategy. Both methods resolve only the flows in the annulus region while modeling the impact introduced by the blade rows. The mathematical formulations and derivations involved in both methods are documented in references 3, 4 for TD2-2) and in reference 5 (for AXOD). The focus of this paper is to discuss the fundamental issues of applicability and compatibility of the two codes as a pair of companion pieces, to perform preliminary design and off-design analysis for modern aircraft engine turbines. Two validation cases for the design and the off-design prediction using TD2-2 and AXOD conducted on two existing high efficiency turbines, developed and tested in the NASA/GE Energy Efficient Engine (GE-E3) Program, the High Pressure Turbine (HPT; two stages, air cooled) and the Low Pressure Turbine (LPT; five stages, un-cooled), are provided in support of the analysis and discussion presented in this paper.

  10. Preliminary study of impact of fuel options on performance of Nuclear Thermal Propulsion (NTP) concepts

    Science.gov (United States)

    Ludewig, H.; Todosow, M.; Montanez, P.; Bezler, P.

    2002-01-01

    A study of the sensitivity to fuel type and composition on the performance of two Nuclear Thermal Rocket (NTR) concepts is presented. The performance measures are the specific impulse and the thrust/weight (T/W) ratio, and the concepts considered are based on the NERVA and ESCORT reactors. For the NERVA concept use of alternative fissile materials showed significant reductions in core mass which improves the values of T/W. However, launch safety considerations may be the dominant factor in selection of fissile material. The use of ternary carbide based fuels allows higher exhaust temperatures, but due to their higher density reduces T/W. The use of molybdenum based cermets, and cermets which use UN or UC2 fuel allow for significant reductions in the reactor mass, and thus an increase in T/W. However, the use of molybdenum reduces the exhaust temperature. Both these results for the NERVA and ESCORT based systems indicate the need to axially zone the core. The lower temperature but lighter material should be used in the cooler (<2500 K) parts of the core, and the heavier, higher temperature material should be used in the outlet end of the core. In addition, the thermal response, and implied stress is estimated for the NERVA concept. .

  11. Preliminary Observations on Sensitivity and Specificity of Magnetization Transfer Asymmetry for Imaging Myelin of Rat Brain at High Field.

    Science.gov (United States)

    Kim, Jae-Woong; Choi, Jiye; Cho, Janggeun; Lee, Chulhyun; Jeon, Daejong; Park, Sung-Hong

    2015-01-01

    Magnetization transfer ratio (MTR) has been often used for imaging myelination. Despite its high sensitivity, the specificity of MTR to myelination is not high because tissues with no myelin such as muscle can also show high MTR. In this study, we propose a new magnetization transfer (MT) indicator, MT asymmetry (MTA), as a new method of myelin imaging. The experiments were performed on rat brain at 9.4 T. MTA revealed high signals in white matter and significantly low signals in gray matter and muscle, indicating that MTA has higher specificity than MTR. Demyelination and remyelination studies demonstrated that the sensitivity of MTA to myelination was as high as that of MTR. These experimental results indicate that MTA can be a good biomarker for imaging myelination. In addition, MTA images can be efficiently acquired with an interslice MTA method, which may accelerate clinical application of myelin imaging.

  12. Preliminary report on the CTS transient event counter performance through the 1976 spring eclipse season

    Science.gov (United States)

    Stevens, N. J.; Lovell, R. R.; Klinect, V. W.

    1977-01-01

    The transient event counter is described, defining its operational characteristics, and presenting the preliminary results obtained through the first 90 days of operation including the Spring 1976 eclipse season. The results show that the CTS was charged to the point where discharges have occurred. The discharge induced transients have not caused any anomalous events in spacecraft operation. The data indicate that discharges can occur at any time during the day without preference to any local time quadrant. The number of discharges occurring in the 1 sec sample interval are greater than anticipated.

  13. Performance of a low-cost methane sensor for ambient concentration measurements in preliminary studies

    Science.gov (United States)

    Eugster, W.; Kling, G. W.

    2012-08-01

    Methane is the second most important greenhouse gas after CO2 and contributes to global warming. Its sources are not uniformly distributed across terrestrial and aquatic ecosystems, and most of the methane flux is expected to stem from hotspots which often occupy a very small fraction of the total landscape area. Continuous time-series measurements of CH4 concentrations can help identify and locate these methane hotspots. Newer, low-cost trace gas sensors such as the Figaro TGS 2600 can detect CH4 even at ambient concentrations. Hence, in this paper we tested this sensor under real-world conditions over Toolik Lake, Alaska, to determine its suitability for preliminary studies before placing more expensive and service-intensive equipment at a given locality. A reasonably good agreement with parallel measurements made using a Los Gatos Research FMA 100 methane analyzer was found after removal of the strong sensitivities for temperature and relative humidity. Correcting for this sensitivity increased the absolute accuracy required for in-depth studies, and the reproducibility between two TGS 2600 sensors run in parallel is very good. We conclude that the relative CH4 concentrations derived from such sensors are sufficient for preliminary investigations in the search of potential methane hotspots.

  14. Influence of Ta Content in High Purity Niobium on Cavity Performance Preliminary Results*

    CERN Document Server

    Kneisel, P

    2004-01-01

    In a previous paper* a program designed to study the influence of the residual tantalum content on the superconducting properties of pure niobium metal for RF cavities was outlined. The main rationale for this program was based on a potential cost reduction for high purity niobium, if a less strict limit on the chemical specification for Ta content, which is not significantly affecting the RRR–value, could be tolerated for high performance cavities. Four ingots with different Ta contents have been melted and transformed into sheets. In each manufacturing step the quality of the material has been monitored by employing chemical analysis, neutron activation analysis, thermal conductivity measurements and evaluation of the mechanical properties. The niobium sheets have been scanned for defects by an eddy current device. From three of the four ingots—Ta contents 100, 600 and 1,200 wppm—two single cell cavities each of the CEBAF variety have been fabricated and a series of tests on each ...

  15. Design and Preliminary Thermal Performance of the Mars Science Laboratory Rover Heat Exchangers

    Science.gov (United States)

    Mastropietro, A. J.; Beatty, John; Kelly, Frank; Birur, Gajanana; Bhandari, Pradeep; Pauken, Michael; Illsley, Peter; Liu, Yuanming; Bame, David; Miller, Jennifer

    2010-01-01

    The challenging range of proposed landing sites for the Mars Science Laboratory Rover requires a rover thermal management system that is capable of keeping temperatures controlled across a wide variety of environmental conditions. On the Martian surface where temperatures can be as cold as -123 degrees Centigrade and as warm as 38 degrees Centigrade, the Rover relies upon a Mechanically Pumped Fluid Loop (MPFL) and external radiators to maintain the temperature of sensitive electronics and science instruments within a -40 degrees Centigrade to 50 degrees Centigrade range. The MPFL also manages significant waste heat generated from the Rover power source, known as the Multi Mission Radioisotope Thermoelectric Generator (MMRTG). The MMRTG produces 110 Watts of electrical power while generating waste heat equivalent to approximately 2000 Watts. Two similar Heat Exchanger (HX) assemblies were designed to both acquire the heat from the MMRTG and radiate waste heat from the onboard electronics to the surrounding Martian environment. Heat acquisition is accomplished on the interior surface of each HX while heat rejection is accomplished on the exterior surface of each HX. Since these two surfaces need to be at very different temperatures in order for the MPFL to perform efficiently, they need to be thermally isolated from one another. The HXs were therefore designed for high in-plane thermal conductivity and extremely low through-thickness thermal conductivity by using aerogel as an insulator inside composite honeycomb sandwich panels. A complex assembly of hand welded and uniquely bent aluminum tubes are bonded onto the HX panels and were specifically designed to be easily mated and demated to the rest of the Rover Heat Recovery and Rejection System (RHRS) in order to ease the integration effort. During the cruise phase to Mars, the HX assemblies serve the additional function of transferring heat from the Rover MPFL to the separate Cruise Stage MPFL so that heat

  16. The problem with total error models in establishing performance specifications and a simple remedy.

    Science.gov (United States)

    Krouwer, Jan S

    2016-08-01

    A recent issue in this journal revisited performance specifications since the Stockholm conference. Of the three recommended methods, two use total error models to establish performance specifications. It is shown that the most commonly used total error model - the Westgard model - is deficient, yet even more complete models fail to capture all errors that comprise total error. Moreover, total error models are often set at 95% of results, which leave 5% of results as unspecified. Glucose meter performance standards are used to illustrate these problems. The Westgard model is useful to asses assay performance but not to set performance specifications. Total error can be used to set performance specifications if the specifications include 100% of the results.

  17. Emergency CT brain: preliminary interpretation with a tablet device: image quality and diagnostic performance of the Apple iPad.

    LENUS (Irish Health Repository)

    Mc Laughlin, Patrick

    2012-04-01

    Tablet devices have recently been used in radiological image interpretation because they have a display resolution comparable to desktop LCD monitors. We identified a need to examine tablet display performance prior to their use in preliminary interpretation of radiological images. We compared the spatial and contrast resolution of a commercially available tablet display with a diagnostic grade 2 megapixel monochrome LCD using a contrast detail phantom. We also recorded reporting discrepancies, using the ACR RADPEER system, between preliminary interpretation of 100 emergency CT brain examinations on the tablet display and formal review on a diagnostic LCD. The iPad display performed inferiorly to the diagnostic monochrome display without the ability to zoom. When the software zoom function was enabled on the tablet device, comparable contrast detail phantom scores of 163 vs 165 points were achieved. No reporting discrepancies were encountered during the interpretation of 43 normal examinations and five cases of acute intracranial hemorrhage. There were seven RADPEER2 (understandable) misses when using the iPad display and 12 with the diagnostic LCD. Use of software zoom in the tablet device improved its contrast detail phantom score. The tablet allowed satisfactory identification of acute CT brain findings, but additional research will be required to examine the cause of "understandable" reporting discrepancies that occur when using tablet devices.

  18. Mission analysis and performance specification studies report. Appendix A. [LYFECC and WANDC

    Energy Technology Data Exchange (ETDEWEB)

    1979-01-25

    The results of Task I, mission analysis and performance specifications, for the Near-Term Hybrid Vehicle (NTHV) development program are presented. The items researched included trip characteristics, market potential, life-cycle cost and performance specifications of NTHV's. (LCL)

  19. 15 CFR 16.11 - Amendment or revision of a performance information labeling specification.

    Science.gov (United States)

    2010-01-01

    ... revision of a performance information labeling specification. The Secretary may by order amend or revise... 15 Commerce and Foreign Trade 1 2010-01-01 2010-01-01 false Amendment or revision of a performance information labeling specification. 16.11 Section 16.11 Commerce and Foreign Trade Office of the Secretary...

  20. 15 CFR 16.5 - Development of performance information labeling specifications.

    Science.gov (United States)

    2010-01-01

    ... publish a proposed Performance Information Labeling Specification in the Federal Register with a notice... 15 Commerce and Foreign Trade 1 2010-01-01 2010-01-01 false Development of performance information labeling specifications. 16.5 Section 16.5 Commerce and Foreign Trade Office of the Secretary of...

  1. From prescription to performance: international trends on concrete specifications and the Brazilian perspective

    Directory of Open Access Journals (Sweden)

    J. Tanesi

    Full Text Available There are two types of specifications: prescriptive and performance based. The prescriptive specifications focus on materials properties, materials proportions, mixing and transporting procedures and on a variety of processes, such as placing and curing. In these specifications, the concrete desired performance it is not necessarily described. On the other hand, performance specifications stipulate what is required from the product and do not prescribe how the product should be produced. In other words, they focus on the desired performance rather than on the concrete ingredients, materials selection, proportioning or construction methods. These are the responsibility of those individuals who contractually have to comply with the specifications. In this case, con- crete is defined in terms of measurable fresh and hardened properties and durability and as there are no restrictions regarding materials and their proportions in the performance specifications, innovative solutions may be used in order to achieve the performance requirements. Currently, most concrete specifications are predominantly prescriptive with some performance requirements. Nevertheless, there is a consensus that in order to extend the service life of concrete structures, this has to be changed. This paper gives an overview of the international specifica- tions and describes the international efforts on the performance specification implementation in the concrete industry.

  2. Mission analysis and performance specification studies report. Appendix A. [LYFECC and WANDC

    Energy Technology Data Exchange (ETDEWEB)

    1979-01-25

    The results of Task I, mission analysis and performance specifications, for the Near-Term Hybrid Vehicle (NTHV) development program are presented. The items researched included trip characteristics, market potential, life-cycle cost and performance specifications of NTHV's. (LCL)

  3. 论初查工作的改进与规范%On the improvement and specification of preliminary investigation

    Institute of Scientific and Technical Information of China (English)

    王洪明; 张加昕

    2011-01-01

    The preliminary investigation work,as an important part of prefiling of prosecutors,has its own particularity and plays a key and decisive role in whether filing the case.However,preliminary investigation work is a pioneering work. There are a lot of uncertainty and instability,which will encounter some unforeseen circumstances.The preliminary investigation itself was flawed and inadequate,so it must be improved and specified.%初查工作作为检察机关一项重要的立案前置环节,具有自身的特殊性,对案件能否立案起关键的决定性作用。但是,初查工作是一项探索性工作,存在诸多不确定性和不稳定性,会遇到一些难以预料的情况,其本身也存在缺陷和不足,故需对其进行相关的改进与规范。

  4. 30 CFR 15.22 - Tolerances for performance, wrapper, and specific gravity.

    Science.gov (United States)

    2010-07-01

    ... specific gravity. 15.22 Section 15.22 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT... performance, wrapper, and specific gravity. (a) The rate of detonation of the explosive shall be within ±15... within ±2 grams of that specified in the approval. (c) The apparent specific gravity of the explosive...

  5. Development of a questionnaire to assess patient satisfaction with allergen-specific immunotherapy in adults: item generation, item reduction, and preliminary validation

    Directory of Open Access Journals (Sweden)

    Justícia JL

    2011-05-01

    Full Text Available Jose Luis Justícia1, Eva Baró2, Victoria Cardona3, Pedro Guardia4, Pedro Ojeda5, José Maria Olaguíbel6, José Maria Vega7, Carmen Vidal81Medical Department, Stallergenes Ibérica, Barcelona, Spain; 2Health Outcomes Research Department, 3D Health Research, Barcelona, Spain; 3Hospital Vall d'Hebron, Barcelona, Spain; 4Hospital Virgen Macarena, Sevilla, Spain; 5Clínica de Asma y Alergia Dres. Ojeda, Madrid, Spain; 6Complejo Hospitalario de Navarra, Pamplona, Spain; 7Hospital Regional Universitario Carlos Haya Málaga, Spain; 8Complejo Hospitalario Universitario de Santiago, Santiago de Compostela, SpainBackground: Allergen-specific immunotherapy (SIT is a treatment capable of modifying the natural course of allergy, so ensuring good adherence to SIT is fundamental. Up until now there has not existed an instrument specifically developed to measure patient satisfaction with SIT, although its assessment could help us to comprehend better and improve treatment adherence and effectiveness. The aim of this study was to develop an instrument to measure adult patient satisfaction with SIT.Methods: Items were generated from a literature review, focus groups with allergic adult patients undergoing SIT, and a meeting with experts. Potential items were administered to allergic patients undergoing SIT in an observational, cross-sectional, multicenter study. Item reduction was based on quantitative and qualitative criteria. A preliminary assessment of feasibility, reliability, and validity of the retained items was performed.Results: An initial pool of 70 items was administered to 257 patients undergoing SIT. Fifty-four items were eliminated resulting in a provisional instrument with 16 items. Factor analysis yielded four factors that were identified as perceived efficacy, activities and environment, cost-benefit balance, and overall satisfaction, explaining 74.8% of variance. Ceiling and floor effects were negligible for overall score. Overall score was

  6. What Degree of Specificity for ESP Courses in EFL Contexts? A Preliminary Case Report for the Degree in Mediterranean food-and-wine Sciences and Health

    Directory of Open Access Journals (Sweden)

    Eugenio Cianflone

    2015-11-01

    Full Text Available The aim of this note is to offer a preliminary discussion of ongoing research on the grade of language specificity necessary for the ESP syllabus designed for the degree in Mediterranean Food-and-wine Sciences and Health at the University of Messina, Italy. The present discussion originates from the perspectives presented by Hyland (2002, advocate of strict adherence to specificity issues in course design, and Huckin (2003, the proponent of a milder view. These opinions are contrasted with a learning context wherein English is a university subject read by freshmen in an environment where all lectures are given in the national idiom. The degree of specificity necessary for this EFL context accounts for learners’ needs in terms of vocabulary, grammar and rhetorical patterns to access discourses, practices and conventions pertaining to their actual studies and to the world of work. In EFL settings, this can mean that specificity results from a compromise between different pedagogical points of view.

  7. Preliminary study of the 270 Bloom Fricke xylenol gel phantom performance for 3D conformal radiotherapy using multiple radiation fields

    Energy Technology Data Exchange (ETDEWEB)

    Cavinato, Christianne C.; Campos, Leticia L., E-mail: ccavinato@ipen.br [Instituto de Pesquisas Energeticas e Nucleares (DIRF/IPEN/CNEN-SP), Sao Paulo, SP (Brazil). Gerencia de Metrologia das Radiacoes; Souza, Benedito H.; Carrete Junior, Henrique; Daros, Kellen A.C.; Medeiros, Regina B. [Universidade Federal de Sao Paulo (UNIFESP), SP (Brazil). Dept. de Diagnostico por Imagens; Giordani, Adelmo J. [Universidade Federal de Sao Paulo (UNIFESP), Sao Paulo, SP (Brazil). Servico de Radioterapia

    2011-07-01

    The complex cancer treatment techniques require rigorous quality control (QC). The Fricke xylenol gel (FXG) dosimeter has been studied to be applied as a three-dimensional (3D) dosimeter since it is possible to produce 3D FXG phantoms of various shapes and sizes. In this preliminary study, the performance of the FXG spherical phantom developed at IPEN, prepared using 270 Bloom gelatin from porcine skin made in Brazil, was evaluated using magnetic resonance imaging technique, aiming to use this phantom to 3D conformal radiotherapy (3DCRT) with multiple radiation fields and clinical photon beams. The obtained results indicate that for all magnetic resonance images of the FXG phantom irradiated with 6 MV clinical photon beam can be observed clearly the target volume and, in the case of coronal image, can also be observed the radiation beam projection and the overlap of different radiation fields used. The Fricke xylenol gel phantom presented satisfactory results for 3DCRT and clinical photon beams in this preliminary study. These results encourage the additional tests using complex treatment techniques and indicate the viability of applying the phantom studied to routine quality control measurements and in 3DCRT and intensity modulated radiotherapy treatment planning. (author)

  8. Appreciating "Thirdspace": An Alternative Way of Viewing and Valuing Site-Specific Dance Performance

    Science.gov (United States)

    Munjee, Tara

    2014-01-01

    Site-specific dance performance involves the presentation of choreography in connection with a site. The context of the site combined with a viewer's personal history, beliefs, and identity impact the reading and appreciation of the performance. Although both stage and site dance performance valuing elicit multiple interpretations of artistic…

  9. Appreciating "Thirdspace": An Alternative Way of Viewing and Valuing Site-Specific Dance Performance

    Science.gov (United States)

    Munjee, Tara

    2014-01-01

    Site-specific dance performance involves the presentation of choreography in connection with a site. The context of the site combined with a viewer's personal history, beliefs, and identity impact the reading and appreciation of the performance. Although both stage and site dance performance valuing elicit multiple interpretations of artistic…

  10. Development and preliminary evaluation of a prototype audiovisual biofeedback device incorporating a patient-specific guiding waveform

    Energy Technology Data Exchange (ETDEWEB)

    Venkat, Raghu B; Sawant, Amit; Suh, Yelin; Keall, Paul J [Department of Radiation Oncology, Stanford University, Stanford, CA 94305-5847 (United States); George, Rohini [Department of Radiation Oncology, Virginia Commonwealth University, Richmond, VA (United States)], E-mail: Paul.Keall@stanford.edu

    2008-06-07

    The aim of this research was to investigate the effectiveness of a novel audio-visual biofeedback respiratory training tool to reduce respiratory irregularity. The audiovisual biofeedback system acquires sample respiratory waveforms of a particular patient and computes a patient-specific waveform to guide the patient's subsequent breathing. Two visual feedback models with different displays and cognitive loads were investigated: a bar model and a wave model. The audio instructions were ascending/descending musical tones played at inhale and exhale respectively to assist in maintaining the breathing period. Free-breathing, bar model and wave model training was performed on ten volunteers for 5 min for three repeat sessions. A total of 90 respiratory waveforms were acquired. It was found that the bar model was superior to free breathing with overall rms displacement variations of 0.10 and 0.16 cm, respectively, and rms period variations of 0.77 and 0.33 s, respectively. The wave model was superior to the bar model and free breathing for all volunteers, with an overall rms displacement of 0.08 cm and rms periods of 0.2 s. The reduction in the displacement and period variations for the bar model compared with free breathing was statistically significant (p = 0.005 and 0.002, respectively); the wave model was significantly better than the bar model (p = 0.006 and 0.005, respectively). Audiovisual biofeedback with a patient-specific guiding waveform significantly reduces variations in breathing. The wave model approach reduces cycle-to-cycle variations in displacement by greater than 50% and variations in period by over 70% compared with free breathing. The planned application of this device is anatomic and functional imaging procedures and radiation therapy delivery. (note)

  11. NOTE: Development and preliminary evaluation of a prototype audiovisual biofeedback device incorporating a patient-specific guiding waveform

    Science.gov (United States)

    Venkat, Raghu B.; Sawant, Amit; Suh, Yelin; George, Rohini; Keall, Paul J.

    2008-06-01

    The aim of this research was to investigate the effectiveness of a novel audio-visual biofeedback respiratory training tool to reduce respiratory irregularity. The audiovisual biofeedback system acquires sample respiratory waveforms of a particular patient and computes a patient-specific waveform to guide the patient's subsequent breathing. Two visual feedback models with different displays and cognitive loads were investigated: a bar model and a wave model. The audio instructions were ascending/descending musical tones played at inhale and exhale respectively to assist in maintaining the breathing period. Free-breathing, bar model and wave model training was performed on ten volunteers for 5 min for three repeat sessions. A total of 90 respiratory waveforms were acquired. It was found that the bar model was superior to free breathing with overall rms displacement variations of 0.10 and 0.16 cm, respectively, and rms period variations of 0.77 and 0.33 s, respectively. The wave model was superior to the bar model and free breathing for all volunteers, with an overall rms displacement of 0.08 cm and rms periods of 0.2 s. The reduction in the displacement and period variations for the bar model compared with free breathing was statistically significant (p = 0.005 and 0.002, respectively); the wave model was significantly better than the bar model (p = 0.006 and 0.005, respectively). Audiovisual biofeedback with a patient-specific guiding waveform significantly reduces variations in breathing. The wave model approach reduces cycle-to-cycle variations in displacement by greater than 50% and variations in period by over 70% compared with free breathing. The planned application of this device is anatomic and functional imaging procedures and radiation therapy delivery.

  12. A Preliminary Investigation into Cognitive Aptitudes Predictive of Overall MQ-1 Predator Pilot Qualification Training Performance

    Science.gov (United States)

    2015-11-06

    other qualitative studies postulating on the cognitive aptitudes critical to the performance of military RPA pilots flying large- sized aircraft at...b Bailey M. Predator pilot and sensor operator selection test batteries . United Kingdom: Cranwell Royal Air...Multidimensional Aptitude Battery II (MAB-II) assesses general intelligence with five distinct verbal intelligence subscales, five distinct performance 4

  13. Performance of Spanish/English bilingual children on a spanish-language neuropsychological battery: preliminary normative data.

    Science.gov (United States)

    Rosselli, Mónica; Ardila, Alfredo; Navarrete, M Gina; Matute, Esmeralda

    2010-05-01

    Despite a population of close to 40 million Hispanics/Latinos in the USA who have at least some level of Spanish/English bilingualism, there are few neuropsychological tests and norms available for this group, especially when assessing Spanish/English bilingual children. The purpose of the present research was to provide preliminary normative data for a bilingual population on a comprehensive neuropsychological battery developed for Spanish-speaking children (Evaluación Neuropsicológica Infantil). Norms by age are presented on the performance of 108 Spanish/English bilingual children (ages 5-14 years) and are expected to be useful when testing other Spanish/English bilingual children in the USA.

  14. Analytical performance specifications: relating laboratory performance to quality required for intended clinical use.

    Science.gov (United States)

    Dalenberg, Daniel A; Schryver, Patricia G; Klee, George G

    2013-03-01

    This article proposes analytic performance goals for five quality indicators: precision, trueness, linearity, detection limits, and consistency across instruments and time. We defined our goals using methods linked to clinical practice data. Goals for desirable precision and trueness are based on biological variation. Linearity goals are related to total error recommendations. Detection limit goals are derived from 0.1 percentile of patient values. Goals for consistency are derived from the variability of distributions of patient test values. Data were collected and evaluated for each of these quality indicators for 46 chemistry tests measured on the Roche cobas 8000 analyzer.

  15. Performance anxiety at English PBL groups among Taiwanese medical students: a preliminary study.

    Science.gov (United States)

    Chen, Cheng-Sheng; Lai, Chung-Sheng; Lu, Peih-Ying; Tsai, Jer-Chia; Chiang, Hung-Che; Huang, In-Ting; Yu, Hsin-Su

    2008-03-01

    Students' performance anxiety can impact negatively on the effectiveness of medical education reform, including performance in problem-based learning (PBL) and in using English in discussion. This study aimed to investigate the nature of performance anxiety among Taiwanese medical students in an English-language PBL group. Eighteen Taiwanese, one American and four Asian medical students who were attending an international PBL workshop were enrolled. A questionnaire seeking demographic data and experience in use of PBL and eight questions evaluating performance anxiety were administered. The performance anxiety of Taiwanese medical students was compared to that of the Asians and the one American. Frequencies of each performance anxiety were calculated. The results suggested that the Taiwanese students showed more anxiety than the one student from the United States, but less than other Asian students. The acts of giving a report, being the center of attention, and talking in the PBL group were the most common situations related to anxiety in PBL groups. Using English and working in a new PBL environment are possible sources of anxiety. The presence of anxiety among the Taiwanese medical students in English PBL groups implies the necessity for developing an effective strategy to deal with students' performance anxiety.

  16. Pneumatic Performance Study of a High Pressure Ejection Device Based on Real Specific Energy and Specific Enthalpy

    Directory of Open Access Journals (Sweden)

    Jie Ren

    2014-09-01

    Full Text Available In high-pressure dynamic thermodynamic processes, the pressure is much higher than the air critical pressure, and the temperature can deviate significantly from the Boyle temperature. In such situations, the thermo-physical properties and pneumatic performance can’t be described accurately by the ideal gas law. This paper proposes an approach to evaluate the pneumatic performance of a high-pressure air catapult launch system, in which esidual functions are used to compensate the thermal physical property uncertainties of caused by real gas effects. Compared with the Nelson-Obert generalized compressibility charts, the precision of the improved virial equation of state is better than Soave-Redlich-Kwong (S-R-K and Peng-Robinson (P-R equations for high pressure air. In this paper, the improved virial equation of state is further used to establish a compressibility factor database which is applied to evaluate real gas effects. The specific residual thermodynamic energy and specific residual enthalpy of the high-pressure air are also derived using the modified corresponding state equation and improved virial equation of state which are truncated to the third virial coefficient. The pneumatic equations are established on the basis of the derived residual functions. The comparison of the numerical results shows that the real gas effects are strong, and the pneumatic performance analysis indicates that the real dynamic thermodynamic process is obviously different from the ideal one.

  17. The role played by performance measurement in the strategy process: a preliminary theoretical summary

    Directory of Open Access Journals (Sweden)

    Jonas Lucio Maia

    2008-08-01

    Full Text Available This paper aims at analyzing the main contributions that Performance Measurement (PM isable to make to the process of formulating, implementing and evaluating business strategies,focusing on collecting the main indications found in the literature. In a nutshell, findingssuggest that Performance Measurement is a manner to portray company’s current situation,based on which strategies will be defined, as well as the fact that several PerformanceMeasurement Systems provide different point of views on how corporate goals should bedefined. Along such trajectory between current and intended, PM may aid the execution ofbenchmarking and the graphical representation of a defined strategy.

  18. Preliminary performance of a vertical-attitude takeoff and landing, supersonic cruise aircraft concept having thrust vectoring integrated into the flight control system

    Science.gov (United States)

    Robins, A. W.; Beissner, F. L., Jr.; Domack, C. S.; Swanson, E. E.

    1985-01-01

    A performance study was made of a vertical attitude takeoff and landing (VATOL), supersonic cruise aircraft concept having thrust vectoring integrated into the flight control system. Those characteristics considered were aerodynamics, weight, balance, and performance. Preliminary results indicate that high levels of supersonic aerodynamic performance can be achieved. Further, with the assumption of an advanced (1985 technology readiness) low bypass ratio turbofan engine and advanced structures, excellent mission performance capability is indicated.

  19. Preliminary Performance Evaluation of a Near Zero Energy Home in Callaway, Florida

    Energy Technology Data Exchange (ETDEWEB)

    Martin, Eric [Florida Solar Energy Center, Cocoa, FL (United States); Parker, Danny [Florida Solar Energy Center, Cocoa, FL (United States); Sherwin, John [Florida Solar Energy Center, Cocoa, FL (United States); Colon, Carlos [Florida Solar Energy Center, Cocoa, FL (United States)

    2009-02-20

    This case study reports on a near zero energy home in Callaway, FL. This paper briefly reviews the design and then focuses on the first four months of energy performance during the second half of 2008.

  20. A Preliminary Axial Fan Design Method with the Considerat ion of Performance and Noise Characteristics

    Science.gov (United States)

    Lee, Chan; Kil, Hyun Gwon

    2010-06-01

    Presented in this paper are a fan's aero-acoustic performance method and its computation procedure which combines aerodynamic flow field data, performances and noise levels of fan. The internal flow field and the performance of fan are analyzed by the through-flow modeling, inviscid pitch-averaged quasi-3D flow analysis combined with flow deviation and pressure loss distribution models. Based on the predicted internal flow field dada by the trough-flow modeling, fan noise is predicted by two models for the discrete frequency noise due to rotating steady aerodynamic thrust and blade interaction and for the broadband noise due to turbulent boundary layer and wake vortex shedding. The present predictions of the flow distribution, the performance and the noise level of fan are well agreed with actual test results.

  1. An appraisal of the 1992 preliminary performance assessment for the Waste Isolation Pilot Plant

    Energy Technology Data Exchange (ETDEWEB)

    Lee, W.W.L.; Chaturvedi, L.; Silva, M.K.; Weiner, R.; Neill, R.H. [Environmental Evaluation Group, Albuquerque, NM (United States)]|[Environmental Evaluation Group, Carlsbad, NM (United States)

    1994-09-01

    The purpose of the New Mexico Environmental Evaluation Group is to conduct an independent technical evaluation of the Waste Isolation Pilot Plant (WIPP) Project to ensure the protection of the public health and safety and the environment. The WIPP Project, located in southeastern New Mexico, is being constructed as a repository for the disposal of transuranic (TRU) radioactive wastes generated by the national defense programs. The Environmental Evaluation Group (EEG) has reviewed the WIPP 1992 Performance Assessment (Sandia WIPP Performance Assessment Department, 1992). Although this performance assessment was released after the October 1992 passage of the WIPP Land Withdrawal Act (PL 102-579), the work preceded the Act. For individual and ground-water protection, calculations have been done for 1000 years post closure, whereas the US Environmental Protection Agency`s Standards (40 CFR 191) issued in 1993 require calculations for 10,000 years. The 1992 Performance Assessment continues to assimilate improved understanding of the geology and hydrogeology of the site, and evolving conceptual models of natural barriers. Progress has been made towards assessing WIPP`s compliance with the US Environmental Protection Agency`s Standards (40 CFR 191). The 1992 Performance Assessment has addressed several items of major concern to EEG, outlined in the July 1992 review of the 1991 performance assessment (Neill et al., 1992). In particular, the authors are pleased that some key results in this performance assessment deal with sensitivity of the calculated complementary cumulative distribution functions (CCDF) to alterative conceptual models proposed by EEG -- that flow in the Culebra be treated as single-porosity fracture-flow; with no sorption retardation unless substantiated by experimental data.

  2. South African exporter performance: new research into firm-specific and market characteristics

    Directory of Open Access Journals (Sweden)

    Christopher May

    2012-05-01

    Full Text Available The export marketing performance of any firm is influenced by a multitude of different factors. Given the multi-faceted nature of the export market, this research study investigated specific factors such as how firm-specific characteristics, product characteristics, market characteristics and export marketing strategies impact on the export marketing performance of South African manufacturing firms. Some of the findings of this research study indicated that firm size, investment commitment and careful planning, as firm-specific characteristics, had a significant influence on export marketing performance. The relationship between export experience and export marketing performance was insignificant. The degree of pricing adaptation and product adaptation had a significant effect on export marketing performance, while this was not the case with respect to the degree of promotion adaptation and distributor support.

  3. Emotional intelligence and its correlation to performance as a resident: a preliminary study.

    Science.gov (United States)

    Talarico, Joseph F; Metro, David G; Patel, Rita M; Carney, Patricia; Wetmore, Amy L

    2008-03-01

    To test the hypothesis that emotional intelligence, as measured by the Bar-On Emotional Quotient Inventory (EQ-I) 125 (Multi Health Systems, Toronto, Ontario, Canada) personal inventory, would correlate with resident performance. Prospective survey. University-affiliated, multiinstitutional anesthesiology residency program. Current clinical anesthesiology years one to three (PGY 2-4) anesthesiology residents enrolled in the University of Pittsburgh Anesthesiology Residency Program. Participants confidentially completed the Bar-On EQ-I 125 survey. Results of the individual EQ-I 125 and daily evaluations by the faculty of the residency program were compiled and analyzed. There was no positive correlation between any facet of emotional intelligence and resident performance. There was statistically significant negative correlation (-0.40; P Emotional intelligence, as measured by the Bar-On EQ-I personal inventory, does not strongly correlate to resident performance as defined at the University of Pittsburgh.

  4. A preliminary study of the effect of eliminating requirements on clinical performance.

    Science.gov (United States)

    Dodge, W W; Dale, R A; Hendricson, W D

    1993-09-01

    This study determined the effect of a clinical program driven by patient needs upon students' productivity, attitudes, and academic performance. A group of eight senior students, whose academic and clinical performance profile replicated that of the rest of the class, were chosen to participate in a year-long non-requirement clinic. The students were expected to attend all clinic sessions, and treat their assigned patients. Their performance was compared to that of classmates in the regular requirement-driven curriculum. The non-requirement group had significantly higher academic achievement and significantly outproduced their classmates. Non-requirement students had no state board failures, versus 17 percent in the regular curriculum, and reported significantly lower stress. This study suggests that predoctoral clinical programs can maintain quality and productivity in the absence of unit requirements.

  5. Design and preliminary performance evaluation of airborne hyper-spectral imaging spectograph Air-OPUS

    Science.gov (United States)

    Okumura, Shin-ichiro; Suzuki, Makoto; Yoshida, Shigeomi; Sano, Takuki; Watanabe, Masaharu; Ogawa, Toshihiro

    2003-06-01

    Air-OPUS is a hyper spectral imaging spectrograph, with 0.34 nm spectral step, 190-455 nm spectral coverage, and 330 spatial channels covering 15 degrees field of view (FOV). It is designed as an airborne instrument for the demonstration of spaceborne-OPUS. After two-demonstration campaign using the Gulfstream-II aircraft, the performances of AIR-OPUS, such as spectral resolution, signal-to-noise ration (SNR) have been evaluated. It is concluded that the performances have agreed with designed value. This paper describes design, the performance, and the first results of Air-OPUS. Concept of next generation Air-OPUS, with wider FOV and visible/near-IR spectral coverage, will be also briefly presented.

  6. Obesity-specific neural cost of maintaining gait performance under complex conditions in community-dwelling older adults.

    Science.gov (United States)

    Osofundiya, Olufunmilola; Benden, Mark E; Dowdy, Diane; Mehta, Ranjana K

    2016-06-01

    Recent evidence of obesity-related changes in the prefrontal cortex during cognitive and seated motor activities has surfaced; however, the impact of obesity on neural activity during ambulation remains unclear. The purpose of this study was to determine obesity-specific neural cost of simple and complex ambulation in older adults. Twenty non-obese and obese individuals, 65years and older, performed three tasks varying in the types of complexity of ambulation (simple walking, walking+cognitive dual-task, and precision walking). Maximum oxygenated hemoglobin, a measure of neural activity, was measured bilaterally using a portable functional near infrared spectroscopy system, and gait speed and performance on the complex tasks were also obtained. Complex ambulatory tasks were associated with ~2-3.5 times greater cerebral oxygenation levels and ~30-40% slower gait speeds when compared to the simple walking task. Additionally, obesity was associated with three times greater oxygenation levels, particularly during the precision gait task, despite obese adults demonstrating similar gait speeds and performances on the complex gait tasks as non-obese adults. Compared to existing studies that focus solely on biomechanical outcomes, the present study is one of the first to examine obesity-related differences in neural activity during ambulation in older adults. In order to maintain gait performance, obesity was associated with higher neural costs, and this was augmented during ambulatory tasks requiring greater precision control. These preliminary findings have clinical implications in identifying individuals who are at greater risk of mobility limitations, particularly when performing complex ambulatory tasks. Copyright © 2016 Elsevier Ltd. All rights reserved.

  7. Nursing Student Performance, 1986-1993: Preliminary Findings. Program Evaluation PE93-1.

    Science.gov (United States)

    Boughan, Karl

    A study was conducted at Prince George's Community College (PGCC), in Maryland, to evaluate nursing student performance from point of admission to the taking of the National Council Licensure Examination (NCLEX). A sample of 853 students who enrolled in the nursing program entry course between fall 1986 and spring 1992 were surveyed to determine…

  8. Learning Strategies and Self-Efficacy as Predictors of Academic Performance: A Preliminary Study

    Science.gov (United States)

    Yip, Michael C. W.

    2012-01-01

    Empirical research supports the idea that differences in academic performance among students are largely due to their different learning and study strategies. The strategies, in turn, affect the self-efficacy of the students. Two hundred university students were recruited to participate in this study by completing a revised Chinese version of the…

  9. Use of organometallic chelates in broiler diet: effect on the performance and bone structure. Preliminary results

    Directory of Open Access Journals (Sweden)

    Biagina Chiofalo

    2010-01-01

    Full Text Available On 26,000 Ross 508 broiler chickens (two groups of 13,000 per pen the effect of dietary substitution with in organic trace minerals or organometallic chelates on performances and bones tructure c trace minerals or organometallic chelates on performances and bone structure was studied. Treatments consisted of a commercial diet integrated with 0.5% of a vitamin-mineral premix containing inorganic trace minerals (CTR or organometallic chelates (MHA using Methionine Hydroxy Analog. Production performance was measured during the 52 d trial period and bone structure was evalu- ated at the slaughter (52 d. Significant (P=0.038 higher values were observed in the finishing period (41 to 52 d for the body weight of the treated group (3560 g vs. 3358 g. The same trend was observed for the ADG (MHA 87.6 g/d vs. CTR 71 g/d; P<0.05. Concerning ash percentage significant higher values were observed in the CTR group for femur (49.01% vs. 51.45%; P<0.01 and tibia (53.87% vs. 49.79%; P<0.001; femur showed also higher values for bone radiopacity (MHA 0.21 px vs. CTR 0.26 px; P=0.035. MHA group showed significant higher value for morphometric measures of the femur and tibia. Results suggest that organometallic chelates can be included in the diet without compromising broiler performance.

  10. Learning Strategies and Self-Efficacy as Predictors of Academic Performance: A Preliminary Study

    Science.gov (United States)

    Yip, Michael C. W.

    2012-01-01

    Empirical research supports the idea that differences in academic performance among students are largely due to their different learning and study strategies. The strategies, in turn, affect the self-efficacy of the students. Two hundred university students were recruited to participate in this study by completing a revised Chinese version of the…

  11. Preliminary Analysis of the General Performance and Mechanical Behavior of Irradiated FeCrAl Base Alloys and Weldments

    Energy Technology Data Exchange (ETDEWEB)

    Gussev, Maxim N. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Field, Kevin G. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Briggs, Samuel A. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Yamamoto, Yukinori [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)

    2016-09-30

    The iron-based, iron-chromium-aluminum (FeCrAl) alloys are promising, robust materials for deployment in current and future nuclear power plants. This class of alloys demonstrates excellent performance in a range of environments and conditions, including high-temperature steam (>1000°C). Furthermore, these alloys have the potential to have prolonged survival under loss-of-coolant accident (LOCA) conditions compared to the more traditional cladding materials that are either Zr-based alloys or austenitic steels. However, one of the issues associated with FeCrAl alloys is cracking during welding. The present project investigates the possibility of mitigating welding-induced cracking via alloying and precise structure control of the weldments; in the frame work of the project, several advanced alloys were developed and are being investigated prior to and after neutron irradiation to provide insight into the radiation tolerance and mechanical performance of the weldments. The present report provides preliminary results on the post-irradiation characterization and mechanical tests performed during United States Fiscal Year (FY) 2016. Chapter 1 provides a general introduction, and Chapter 2 describes the alloy compositions, welding procedure, specimen geometry and manufacturing parameters. Also, a brief discussion of the irradiation at the High Flux Isotope Reactor (HFIR) is provided. Chapter 3 is devoted to the analysis of mechanical tests performed at the hot cell facility; tensile curves and mechanical properties are discussed in detail focusing on the irradiation temperature. Limited fractography results are also presented and analyzed. The discussion highlights the limitations of the testing within a hot cell. Chapter 4 underlines the advantages of in-situ testing and discusses the preliminary results obtained with newly developed miniature specimens. Specimens were moved to the Low Activation Materials Development and Analysis (LAMDA) laboratory and prepared for

  12. Preliminary Analysis of the General Performance and Mechanical Behavior of Irradiated FeCrAl Base Alloys and Weldments

    Energy Technology Data Exchange (ETDEWEB)

    Gussev, Maxim N [ORNL; Field, Kevin G [ORNL; Yamamoto, Yukinori [ORNL

    2016-09-01

    The iron-based, iron-chromium-aluminum (FeCrAl) alloys are promising, robust materials for deployment in current and future nuclear power plants. This class of alloys demonstrates excellent performance in a range of environments and conditions, including high-temperature steam (>1000 C). Furthermore, these alloys have the potential to survive greater durations under lost-of-coolant incident (LOCA) conditions compared to the more traditional cladding materials that are Zr-based or austenitic steels. However, one of the issues associated with FeCrAl alloys is cracking during welding. The present project investigates the possibility to mitigate welding-induced cracking via alloying and precise structure control of the weldments; in the frame work of the project, several advanced alloys were developed and are being investigated prior to and after neutron irradiation to provide insight into the radiation tolerance and mechanical performance of the weldments. The present report provides preliminary, working results on the post-irradiation characterization and mechanical tests performed during United States Fiscal Year (FY) 2016. Chapter 1 provides a general introduction, and Chapter 2 describes the alloy compositions, welding procedure, specimen geometry and manufacturing. Also, a brief discussion of the irradiation at the High-Flux Isotope Reactor (HFIR) is provided. Chapter 3 is devoted to the analysis of mechanical tests performed at the hot cell facility; tensile curves and mechanical properties are discussed in details focusing on the irradiation temperature role. Limited fractography results are also given and analyzed. The discussion highlights the limitations of the testing at the hot cell. Chapter 4 underlines the advantages of in-situ testing and discusses the preliminary results obtained with newly developed miniature specimens. Specimens were moved to the Low Activation Materials Development Laboratory (LAMDA) and prepared for mechanical tests. Follow-on SEM

  13. Affective States and Performance Outcomes – The Findings of Preliminary Research Involving Pentathletes

    Directory of Open Access Journals (Sweden)

    Samełko Aleksandra

    2016-03-01

    Full Text Available Introduction. The aim of this article is to discuss the relationship between affective states experienced by athletes and the outcome of their performance. The article presents the findings of a pilot study which made it possible to determine the relationship between the emotional states, mood, and level of stress of a group of pentathletes and the outcomes they achieved in a sports competition. Material and methods. The study involved 12 senior modern pentathletes, including 7 male and 5 female athletes. The following standard psychology questionnaires were used in the study: the 10-item Perceived Stress Scale (PSS-10, the Positive and Negative Affect Schedule (PANAS, and the Profile of Mood State (POMS. Performance was assessed based on the number of points achieved by the pentathletes in particular events in the pentathlon, which are held according to the rules set by the International Modern Pentathlon Union (UIPM. Results. The findings of the study confirmed that there was a correlation between the athletes’ mood and emotions and the outcome of their performance. The level of stress strongly negatively correlated with both the outcome they expected to achieve and the one they actually achieved for the combined event (running and shooting. For this event a relationship was also found between the athletes’ affective states and their outcomes: in running and shooting there was a positive and statistically significant correlation between the level of positive emotions and anger and the results achieved. However, friendliness, one of the other affective state variables that were measured, correlated negatively with the outcomes of the athletes’ performance. Conclusions. In the group of pentathletes who participated in the study, a high level of anger was associated with better outcomes, and a high level of friendliness had an adverse effect on the results achieved. The findings of the current study confirm that there is a relationship

  14. A Domain Specific Language for Performance Evaluation of Medical Imaging Systems

    NARCIS (Netherlands)

    van den Berg, Freek; Remke, Anne Katharina Ingrid; Haverkort, Boudewijn R.H.M.; Turau, Volker; Kwiatkowska, Marta; Mangharam, Rahul; Weyer, Christoph

    2014-01-01

    We propose iDSL, a domain specific language and toolbox for performance evaluation of Medical Imaging Systems. iDSL provides transformations to MoDeST models, which are in turn converted into UPPAAL and discrete-event MODES models. This enables automated performance evaluation by means of model

  15. Cross-Situational Specificity in Managers' Perceptions of Subordinate Performance, Attributions, and Leader Behaviors.

    Science.gov (United States)

    James, Lawrence R.; White, John F.

    1983-01-01

    Examined managers' perceptions of subordinates' performance, causes (attributions) of subordinates' performance, and the leader behaviors they employed toward subordinates from the standpoint of cross-situational consistency versus cross-situational specificity. Empirical results for 377 Navy managers provided strong support for cross-situational…

  16. Preliminary evidence for performance enhancement following parietal lobe stimulation in Developmental Dyscalculia.

    Science.gov (United States)

    Iuculano, Teresa; Cohen Kadosh, Roi

    2014-01-01

    Nearly 7% of the population exhibit difficulties in dealing with numbers and performing arithmetic, a condition named Developmental Dyscalculia (DD), which significantly affects the educational and professional outcomes of these individuals, as it often persists into adulthood. Research has mainly focused on behavioral rehabilitation, while little is known about performance changes and neuroplasticity induced by the concurrent application of brain-behavioral approaches. It has been shown that numerical proficiency can be enhanced by applying a small-yet constant-current through the brain, a non-invasive technique named transcranial electrical stimulation (tES). Here we combined a numerical learning paradigm with transcranial direct current stimulation (tDCS) in two adults with DD to assess the potential benefits of this methodology to remediate their numerical difficulties. Subjects learned to associate artificial symbols to numerical quantities within the context of a trial and error paradigm, while tDCS was applied to the posterior parietal cortex (PPC). The first subject (DD1) received anodal stimulation to the right PPC and cathodal stimulation to the left PPC, which has been associated with numerical performance's improvements in healthy subjects. The second subject (DD2) received anodal stimulation to the left PPC and cathodal stimulation to the right PPC, which has been shown to impair numerical performance in healthy subjects. We examined two indices of numerical proficiency: (i) automaticity of number processing; and (ii) mapping of numbers onto space. Our results are opposite to previous findings with non-dyscalculic subjects. Only anodal stimulation to the left PPC improved both indices of numerical proficiency. These initial results represent an important step to inform the rehabilitation of developmental learning disabilities, and have relevant applications for basic and applied research in cognitive neuroscience, rehabilitation, and education.

  17. Evaluation of Muscle Performance in Patients with Vitamin D De ciency: Preliminary Study

    Directory of Open Access Journals (Sweden)

    Gökhan Tuna Öztürk

    2013-04-01

    Full Text Available Aim: Vitamin D de ciency is very common in general population and has potentially harmful effect on musculoskeletal system. We aimed to show the effect of vitamin D de ciency on the muscle performance by using isokinetic test. Meterial and Methods: This study includes 12 women with vitamin D de ciency for patient group and 12 healthy women for control group. We compared knee muscles performance of these two groups by using isokinetic test. Results: The mean age was 40.71 (26-57 years in patients and 41.43 (28-58 years in healthy group. There was no statistical difference between two groups at knee  exion and extension pick-torque values in 60°/s velocity and fatigue index in 180°/s velocity (respectively, p1=0.86, p2=0.12, p3=0.42. Conclusion: Vitamin D de ciency has no effect on muscle performance. Further invastigations that evaluating larger populations are needed. (Turkish Journal of Osteoporosis 2013;19: 17-9

  18. Effect of Digestarom® dietary supplementation on the reproductive performances of rabbit does: preliminary results

    Directory of Open Access Journals (Sweden)

    Chiara Celia

    2015-12-01

    Full Text Available The study investigated the effect of Digestarom® dietary supplementation on the reproductive performances of rabbit does. Pannon Ka (maternal line multiparous does were randomly divided into two dietary groups since insemination and fed ad libitum. In the first group (n=51, rabbit does were fed with a commercial diet (C, whereas in the other group (n=52 they received the same diet supplemented with 300 mg/kg of Digestarom® (D. The experiment lasted for two reproductive cycles (kindling 1=K1; kindling 2=K2. Body weight of does and litter size (kits born total, alive, stillborn were recorded at kindling. Litter size and litter weight were registered at 7, 14, 21 days of age after nursing, and the average individual weight of kits was calculated. Kits’ mortality was recorded daily. At K1, rabbit does performances were unaffected by dietary treatments. During K2, D does were significantly lighter than C ones (P<0.05 and displayed a lower kindling rate (P<0.05. Digestarom® did not improve the reproductive performance of rabbit does. They seemed to dislike the D diet in K1 and such behavior could have led to the negative results in K2. Further studies should focus on feed acceptance, dose-dependent effect, physiological adaptation and in vivo oxidative status of does. Finally, several consecutive reproductive cycles are recommended to test the efficacy of new feed supplements.

  19. Word memory test performance in Canadian adolescents with learning disabilities: a preliminary study.

    Science.gov (United States)

    Larochette, Anne-Claire; Harrison, Allyson G

    2012-01-01

    The purpose of this study was to evaluate Word Memory Test (WMT) performances in students with identified learning disabilities (LDs) providing good effort to examine the influence of severe reading or learning problems on WMT performance. Participants were 63 students with LDs aged 11 to 14 years old (M = 12.19 years), who completed psychoeducational assessments as part of a transition program to secondary school. Participants were administered a battery of psychodiagnostic tests including the WMT. Results indicated that 9.5% of students with LD met Criterion A on the WMT (i.e., perform below cut-offs on any of the first three subtests of the WMT), but less than 1% met both criteria necessary for identification of low effort. Failure on the first three subtests of the WMT was associated with word reading at or below the 1st percentile and severely impaired phonetic decoding and phonological awareness skills. These results indicate that the majority of students with a history of LD are capable of passing the WMT, and use of profile analysis reduces the false-positive rate to below 1%.

  20. Preliminary performance studies for the ATLAS Muon Trigger during initial Run 2

    CERN Document Server

    Reale, Marilea; The ATLAS collaboration

    2015-01-01

    The physics program of the ATLAS experiment at CERN's Large Hadron Collider (LHC) includes the search for the Higgs Boson and the measurements of its properties, searches for new physics and precision measurements of the Standard Model. Events with high momentum muons in the final state are an important signature of many of these physics topics, then an efficient muon trigger and a deep understanding of its performance are crucial. During Run 1 the ATLAS muon trigger was successfully adapted to the challenging environment, thus reaching an excellent performance. During Run 2 ~100 pb-1 of data with 50 ns bunch spacing have been already collected, while the collection of data with 25 ns bunch spacing is currently ongoing. As the data taking proceeds, the muon trigger performance is being constantly monitored. The muon trigger efficiency, studied both with respect to offline muon reconstruction and with Tag&Probe method applied to the Z decays in muon pairs, is presented here as a function of different kinem...

  1. Diagnostic performance of 320-detector CT coronary angiography in patients with atrial fibrillation: preliminary results

    Energy Technology Data Exchange (ETDEWEB)

    Xu, Lei; Yang, Lin; Fan, Zhanming; Yu, Wei; Lv, Biao; Zhang, Zhaoqi [Capital Medical University, Department of Radiology, Beijing Anzhen Hospital, Beijing (China)

    2011-05-15

    To evaluate the feasibility, diagnostic accuracy, and radiation dose of CT coronary angiography (CTCA) in patients with atrial fibrillation (AF) using 320-detector CT. Thirty-seven patients with persistent AF and suspected coronary artery disease (CAD) were enrolled. All patients underwent both 320-detector CTCA and conventional coronary angiography (CCA). CT image quality and the presence of significant ({>=}50%) stenosis were evaluated by two radiologists blinded to the results of CCA. The sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) were calculated using CCA as the reference standard. Differences in detection of coronary artery stenosis between 320-detector CTCA and CCA were evaluated with McNemar's test. Patient radiation dose was calculated by multiplying dose length product by conversion coefficient of 0.017. In total 474 evaluated coronary segments, 459 (96.8%) segments were diagnostically evaluable. On per-segment analysis, sensitivity, specificity, PPV and NPV were 90.0% (18 of 20), 99.3% (436 of 439), 85.7% (18 of 21) and 99.5% (436 of 438). No significant difference was found between 320-detector CTCA and CCA on the detection of significant stenosis (P = 1.000). Effective doses of 320-detector CTCA was 13.0 {+-} 4.7 mSv. 320-detector CTCA is feasible and accurate in excluding CAD in patients with AF. (orig.)

  2. Preliminary evidence for performance enhancement following parietal lobe stimulation in Developmental Dyscalculia

    Directory of Open Access Journals (Sweden)

    Teresa eIuculano

    2014-02-01

    Full Text Available Nearly 7% of the population exhibit difficulties in dealing with numbers and performing arithmetic, a condition named Developmental Dyscalculia (DD, which significantly affects the educational and professional outcomes of these individuals, as it often persists into adulthood. Research has mainly focused on behavioral rehabilitation, while little is known about performance changes and neuroplasticity induced by the concurrent application of brain-behavioral approaches. It has been shown that numerical proficiency can be enhanced by applying a small – yet constant – current through the brain, a non-invasive technique named transcranial electrical stimulation (tES. Here we combined a numerical learning paradigm with transcranial direct current stimulation (tDCS in two adults with DD to assess the potential benefits of this methodology to remediate their numerical difficulties. Subjects learned to associate artificial symbols to numerical quantities within the context of a trial and error paradigm, while tDCS was applied to the posterior parietal cortex (PPC. The first subject (DD1 received anodal stimulation to the right PPC and cathodal stimulation to the left PPC, which has been associated with numerical performance’s improvements in healthy subjects. The second subject (DD2 received anodal stimulation to the left PPC and cathodal stimulation to the right PPC, which has been shown to impair numerical performance in healthy subjects. We examined two indices of numerical proficiency: (i automaticity of number processing; and (ii mapping of numbers onto space. Our results are opposite to previous findings with non-dyscalculic subjects. Only anodal stimulation to the left PPC improved both indices of numerical proficiency. These initial results represent an important step to inform the rehabilitation of developmental learning disabilities, and have relevant applications for basic and applied research in cognitive neuroscience, rehabilitation

  3. Performance of a FieldSpec spectroradiometer for aerosol optical depth retrieval: method and preliminary results.

    Science.gov (United States)

    Bassani, Cristiana; Estellés, Víctor; Campanelli, Monica; Cavalli, Rosa Maria; Martínez-Lozano, José Antonio

    2009-04-10

    The performance of a FieldSpec spectroradiometer for retrieving aerosol optical depth (AOD) has been assessed after modifying its basic configuration in order to measure direct solar irradiance at ground level. The FieldSpec measurements were obtained during four summertime days in the years 2004 and 2005, over a Spanish agricultural site in Barrax, Albacete (30 degrees 3(') N, 2 degrees 6(') W, 700 m a.s.l.), in the framework of two European Space Agency mission remote sensing field campaigns. From the whole FieldSpec spectral domain (350-2500 nm) the AOD was extracted for channels within atmospheric windows. The instrument was calibrated by means of the standard Langley plot method, performed at a high mountain site in Italy. The AOD retrieved by the FieldSpec has been validated by comparison with the AOD obtained from a colocated CIMEL CE318 Sun photometer. The FieldSpec AOD spectra were convoluted with the CE318 filter transmission functions in order to make both datasets comparable. Our results show that both datasets are very similar (R(2) around 0.9) for all the channels from the CE318, with an average deviation of about 0.02. The temporal evolution of the AOD was accurately monitored by the FieldSpec under different atmospheric conditions, as was the case for a previously reported mineral dust intrusion. As a conclusion, the comparison performed in this study shows that the FieldSpec spectroradiometer is a suitable instrument for retrieving the AOD in different atmospheric situations.

  4. Tonal cues modulate line bisection performance: Preliminary evidence for a new rehabilitation prospect?

    Directory of Open Access Journals (Sweden)

    Masami eIshihara

    2013-10-01

    Full Text Available The effect of the presentation of two different auditory pitches (high & low on manual line-bisection performance was studied to investigate the relationship between space and magnitude representations underlying motor acts. Participants were asked to mark the midpoint of a given line with a pen while they were listening a pitch via headphones. In healthy participants, the effect of the presentation order (blocked or alternative way of auditory stimuli was tested (Exp. 1. The results showed no biasing effect of pitch in blocked-order presentation, whereas the alternative presentation modulated the line-bisection. Lower pitch produced leftward or downward bisection biases whereas higher pitch produced rightward or upward biases, suggesting that visuomotor processing can be spatially modulated by irrelevant auditory cues. In Exp. 2, the effect of such alternative stimulations in line bisection in right brain damaged patients with a unilateral neglect and without a neglect was tested. Similar biasing effects caused by auditory cues were observed although the white noise presentation also affected the patient’s performance. Additionally, the effect of pitch difference was larger for the neglect patient than for the no-neglect patient as well as for healthy participants. The neglect patient’s bisection performance gradually improved during the experiment and was maintained even after one week. It is therefore concluded that auditory cues, characterized by both the pitch difference and the dynamic alternation, influence spatial representations. The larger biasing effect seen in the neglect patient compared to the no-neglect patient and healthy participants suggests that auditory cues could modulate the direction of the attentional bias that is characteristic of neglect patients. Thus the alternative presentation of auditory cues could be used as rehabilitation for neglect patients. The space-pitch associations are discussed in terms of a

  5. Cryogenic irradiation of an EMCCD for the WFIRST coronagraph: preliminary performance analysis

    Science.gov (United States)

    Bush, Nathan; Hall, David; Holland, Andrew; Burgon, Ross; Murray, Neil; Gow, Jason; Jordan, Douglas; Demers, Richard; Harding, Leon K.; Nemati, Bijan; Hoenk, Michael; Michaels, Darren; Peddada, Pavani

    2016-08-01

    The Wide Field Infra-Red Survey Telescope (WFIRST) is a NASA observatory scheduled to launch in the next decade that will settle essential questions in exoplanet science. The Wide Field Instrument (WFI) offers Hubble quality imaging over a 0.28 square degree field of view and will gather NIR statistical data on exoplanets through gravitational microlensing. An on-board coronagraph will for the first time perform direct imaging and spectroscopic analysis of exoplanets with properties analogous to those within our own solar system, including cold Jupiters, mini Neptunes and potentially super Earths. The Coronagraph Instrument (CGI) will be required to operate with low signal flux for long integration times, demanding all noise sources are kept to a minimum. The Electron Multiplication (EM)-CCD has been baselined for both the imaging and spectrograph cameras due its ability to operate with sub-electron effective read noise values with appropriate multiplication gain setting. The presence of other noise sources, however, such as thermal dark signal and Clock Induced Charge (CIC), need to be characterized and mitigated. In addition, operation within a space environment will subject the device to radiation damage that will degrade the Charge Transfer Effciency (CTE) of the device throughout the mission lifetime. Irradiation at the nominal instrument operating temperature has the potential to provide the best estimate of performance degradation that will be experienced in-flight, since the final population of silicon defects has been shown to be dependent upon the temperature at which the sensor is irradiated. Here we present initial findings from pre- and post- cryogenic irradiation testing of the e2v CCD201-20 BI EMCCD sensor, baselined for the WFIRST coronagraph instrument. The motivation for irradiation at cryogenic temperatures is discussed with reference to previous investigations of a similar nature. The results are presented in context with those from a previous

  6. Evaluating Method Engineer Performance: an error classification and preliminary empirical study

    Directory of Open Access Journals (Sweden)

    Steven Kelly

    1998-11-01

    Full Text Available We describe an approach to empirically test the use of metaCASE environments to model methods. Both diagrams and matrices have been proposed as a means for presenting the methods. These different paradigms may have their own effects on how easily and well users can model methods. We extend Batra's classification of errors in data modelling to cover metamodelling, and use it to measure the performance of a group of metamodellers using either diagrams or matrices. The tentative results from this pilot study confirm the usefulness of the classification, and show some interesting differences between the paradigms.

  7. Summary on the preliminary assessment of the T91 window performance in the MEGAPIE conditions

    Energy Technology Data Exchange (ETDEWEB)

    Dai, Y. [Spallation Neutron Source Division, Paul Scherrer Institut, CH-5232 Villigen PSI (Switzerland); Fazio, C. [Program Nuclear Safety Research, Forschungszentrum Karlsruhe, 76021 Karlsruhe (Germany)]. E-mail: concetta.fazio@nuklear.fzk.de; Gorse, D. [CNRS - CECM, 15 Rue G. Urbain, Vitry sur Seine cedex (France); Groeschel, F. [Spallation Neutron Source Division, Paul Scherrer Institut, CH-5232 Villigen PSI (Switzerland); Henry, J. [Commissariat a l' Energie Atomique, Saclay, 91191 Gif sur Yvette cedex (France); Terlain, A. [Commissariat a l' Energie Atomique, Saclay, 91191 Gif sur Yvette cedex (France); Vogt, J.-B. [Laboratoire de Metallurgie Physique et Genie des Materiaux, Universite de Lille1, 59655 Villeneuve d' Ascq cedex (France); Auger, T. [CNRS - CECM, 15 Rue G. Urbain, Vitry sur Seine cedex (France); Gessi, A. [Ente per le Nuove Tecnologie l' Energia e l' Ambiente, CR Brasimone, 40032 Camugnano Bologna (Italy)

    2006-06-23

    The MEGAwatt PIlot Experiment (MEGAPIE) target is a liquid lead-bismuth eutectic neutron spallation target, which is considered as a key experiment for the development of accelerator driven systems to transmute high level nuclear waste. The target has been designed in the frame of an international collaboration and it will be installed and irradiated at the SINQ facility of the Paul Scherrer Institut, Switzerland. This paper summarises the experiments done to assess the performance of the MEGAPIE window material, which is made of martensitic steel T91.

  8. A Preliminary Assessment of the S-3A SRAL Performances in SAR Mode

    Science.gov (United States)

    Dinardo, Salvatore; Scharroo, Remko; Bonekamp, Hans; Lucas, Bruno; Loddo, Carolina; Benveniste, Jerome

    2016-08-01

    The present work aims to assess and characterize the S3-A SRAL Altimeter performance in closed-loop tracking mode and in open ocean conditions. We have processed the Sentinel-3 SAR data products from L0 until L2 using an adaptation of the ESRIN GPOD CryoSat-2 Processor SARvatore.During the Delay-Doppler processing, we have chosen to activate the range zero-padding option.The L2 altimetric geophysical parameters, that are to be validated, are the sea surface height above the ellipsoid (SSH), sea level anomaly (SLA), the significant wave height (SWH) and wind speed (U10), all estimated at 20 Hz.The orbit files are the POD MOE, while the geo- corrections are extracted from the RADS database.In order to assess the accuracy of the wave&wind products, we have been using an ocean wave&wind speed model output (wind speed at 10 meter high above the sea surface) from the ECMWF.We have made a first order approximation of the sea state bias as -4.7% of the SWH.In order to assess the precision performance of SRAL SAR mode, we compute the level of instrumental noise (range, wave height and wind speed) for different conditions of sea state.

  9. Preliminary Evaluation of Inclusion of Oregano Extract on Growth Performance in Fattening Rabbits

    Directory of Open Access Journals (Sweden)

    Katerine Alexandra Prieto García

    2014-08-01

    Full Text Available   Oregano as vegetal extract has been investigated scientifically and has proven to be an effective antibiotic; it does not generate resistant strains as it happens with the use of antibiotic growth promoters (AGP, and is also considered an alternative to improve productive performance in livestock farms. This is why the aim of study was to evaluate the use of oregano extract on the gain of final weight, conversion and feed efficiency in rabbits, for this purpose an experiment completely randomized with 12 New Zealand rabbits divided into 3 treatment was performed; T1, was determined as control, and the base feed was 100 g of rabbit feed; T2, to 100 g of rabbit feed was added 1 ml of oregano extract and T3, 100 g of rabbit feed plus 3 ml of oregano. The research lasted 60 days, 8 which were dietary adaptation. The obtained data were evaluated by ANOVA and the statistical differences between treatments by TUKEY test, with significance level of 0,05. The results showed statistically significant difference (p < 0.05 for the variables final weight gain and feed efficiency for T1 relative to T2 and T3; for feed conversion no statistical difference (p>0.05 between treatments. For this experiment it was concluded that the addition of oregano extract showed no improvement in productive parameters of broiler rabbits.

  10. West Village Community: Quality Management Processes and Preliminary Heat Pump Water Heater Performance

    Energy Technology Data Exchange (ETDEWEB)

    Dakin, B.; Backman, C.; Hoeschele, M.; German, A.

    2012-11-01

    West Village, a multi-use project underway at the University of California Davis, represents a ground-breaking sustainable community incorporating energy efficiency measures and on-site renewable generation to achieve community-level Zero Net Energy (ZNE) goals. The project when complete will provide housing for students, faculty, and staff with a vision to minimize the community's impact on energy use by reducing building energy use, providing on-site generation, and encouraging alternative forms of transportation. This focus of this research is on the 192 student apartments that were completed in 2011 under Phase I of the West Village multi-year project. The numerous aggressive energy efficiency measures implemented result in estimated source energy savings of 37% over the B10 Benchmark. There are two primary objectives of this research. The first is to evaluate performance and efficiency of the central heat pump water heaters as a strategy to provide efficient electric water heating for net-zero all-electric buildings and where natural gas is not available on site. In addition, effectiveness of the quality assurance and quality control processes implemented to ensure proper system commissioning and to meet program participation requirements is evaluated. Recommendations for improvements that could improve successful implementation for large-scale, high performance communities are identified.

  11. West Village Community. Quality Management Processes and Preliminary Heat Pump Water Heater Performance

    Energy Technology Data Exchange (ETDEWEB)

    Dakin, B. [Alliance for Residential Building Innovation (ARBI), Davis, CA (United States); Backman, C. [Alliance for Residential Building Innovation (ARBI), Davis, CA (United States); Hoeschele, M. [Alliance for Residential Building Innovation (ARBI), Davis, CA (United States); German, A. [Alliance for Residential Building Innovation (ARBI), Davis, CA (United States)

    2012-11-01

    West Village, a multi-use project underway at the University of California Davis, represents a ground-breaking sustainable community incorporating energy efficiency measures and on-site renewable generation to achieve community-level Zero Net Energy (ZNE) goals. When complete, the project will provide housing for students, faculty, and staff with a vision to minimize the community’s impact on energy use by reducing building energy use, providing on-site generation, and encouraging alternative forms of transportation. This focus of this research is on the 192 student apartments that were completed in 2011 under Phase I of the West Village multi-year project. The numerous aggressive energy efficiency measures implemented result in estimated source energy savings of 37% over the B10 Benchmark. There are two primary objectives of this research. The first is to evaluate performance and efficiency of the central heat pump water heaters as a strategy to provide efficient electric water heating for net-zero all-electric buildings and where natural gas is not available on site. In addition, effectiveness of the quality assurance and quality control processes implemented to ensure proper system commissioning and to meet program participation requirements is evaluated. Recommendations for improvements that could improve successful implementation for large-scale, high performance communities are identified.

  12. Effects of general, specific and combined warm-up on explosive muscular performance

    Directory of Open Access Journals (Sweden)

    David Cristobal Andrade

    2015-02-01

    Full Text Available The purpose of this study was to compare the acute effects of general, specific and combined warm-up (WU on explosive performance. Healthy male (n=10 subjects participated in six WU protocols in a crossover randomized study design. Protocols were: passive rest (PR; 15 min of passive rest, running (Run; 5 min of running at 70% of maximum heart rate, stretching (STR; 5 min of static stretching exercise, jumping [Jump; 5 min of jumping exercises – 3x8 countermovement jumps (CMJ and 3x8 drop jumps from 60 cm (DJ60], and combined (COM; protocols Run + STR + Jump combined. Immediately before and after each WU, subjects were assessed for explosive concentric-only (i.e. squat jump – SJ, slow stretch-shortening cycle (i.e. CMJ, fast stretch-shortening cycle (i.e. DJ60 and contact time (CT muscle performance. PR significantly reduced SJ performance (p =0.007. Run increased SJ (p =0.0001 and CMJ (p =0.002. STR increased CMJ (p =0.048. Specific WU (i.e. Jump increased SJ (p =0.001, CMJ (p =0.028 and DJ60 (p =0.006 performance. COM increased CMJ performance (p =0.006. Jump was superior in SJ performance vs. PR (p =0.001. Jump reduced (p =0.03 CT in DJ60. In conclusion, general, specific and combined WU increase slow stretch-shortening cycle (SSC muscle performance, but only specific WU increases fast SSC muscle performance. Therefore, to increase fast SSC performance, specific fast SSC muscle actions must be included during the WU.

  13. Effect of goal difficulty, goal specificity and duration of practice time intervals on muscular endurance performance.

    Science.gov (United States)

    Bar-Eli, M; Tenenbaum, G; Pie, J S; Btesh, Y; Almog, A

    1997-04-01

    The aims of this study were to explore the relationships between goal specificity, goal difficulty and performance, and to determine if setting unrealistic goals would produce decreases in performance. The subjects were high school students from 15 schools and an attempt was made to control for the effects of social comparison. The schools were randomly assigned to one of 15 conditions representing five levels of goal conditions-namely, 'do' (no goals), 'do your best', 'improve by 10%' (easy), 'improve by 20%' (difficult/ realistic) and 'improve by 40%' (improbable/unattainable)-and three levels of practice duration (4, 6 and 8 weeks). This design consisted of nesting goal difficulty within practice duration, which enabled an examination of the goal specificity and goal attainability/difficulty hypotheses proposed by Locke and Latham (1985). A 5 x 3 factorial ANCOVA was applied to the post-baseline sit-up gain scores. The results indicated that all specific groups performed better than all non-specific groups. In addition, across practice durations the difficult/realistic group exhibited the greatest increase in performance, followed by the easy group. The performance gains of the improbable/unattainable group were substantially less compared with the difficult/ realistic group after 4 and 6 weeks, but not after 8 weeks of practice. These results are in line with both the goal specificity and goal difficulty hypotheses derived from the application of Locke's goal-setting theory to sport.

  14. Preliminary analysis of left-right ambiguity resolution performance for twin-line array

    Institute of Scientific and Technical Information of China (English)

    LI Qihu

    2007-01-01

    It is well known that the single line array sonar can't identify whether the target comes from left or right. Multi-line array provides the possibility to solve the left-right ambiguity problem. The performance of left-right resolution for twin-line array is described in this paper.It is shown that the suppression ratio, which is defined as the ratio of the response in the steering direction to opposite symmetrical direction, can be considered as an index for evaluating the ability of solving left-right ambiguity. The characteristics of suppression ratio is discussed. The theoretical expression for suppression ratio and some numerical results are illustrated. The result of theoretical analysis can be used in design of twin-line array sonar.

  15. Preliminary Performance Evaluation of MEMS-based Piezoelectric Energy Harvesters in Extended Temperature Range

    DEFF Research Database (Denmark)

    Xu, R.; Borregaard, L.M.; Lei, A.

    2012-01-01

    In this work a batch of MEMS-based vibration energy harvesters consisting of a silicon/PZT thick film ntilever with integrated proof mass is characterized. The purpose of a vibration energy harvester is to convert low grade vibrations to useful electrical power. Optimally, the natural frequency...... of the harvester should match the frequency of he ambient vibration. The first step to achieve this is to evaluate the uniformity of the fabricated harvesters and nderstand the effects of temperature on the harvesters during operation. Therefore, the uniformity of 40 energy harvesters from one wafer has been...... evaluated. Thereafter the performance of the energy harvesters operating at emperatures between -30°C to 100°C was measured....

  16. Preliminary Validation of High Performance Liquid Chromatography Method for Detection of Methyltestosterone Residue in Carp Muscle

    Institute of Scientific and Technical Information of China (English)

    JIANG Jie; LIN Hong; FU Xiaoting; LI Mingming

    2005-01-01

    The use of synthetic anabolic steroid methyltestosterone (MT) as growth promoter is prohibited in China. Validations of analytical methods for MT residue in food and the results obtained have become indispensable. The high performance liquid chromatography (HPLC) method for the detection of MT with liquid-liquid extraction by trichloromethanemethanol in carp muscle tissue was preliminarily validated with reference to the following parameters: recovery (accuracy)at the 1, 5 and 10 mgkg-1 level, between-run and within-run CV values (repeatability, also called relative standard deviation(RSD)) and limit of detection. The recoveries were above 80% and the between-run and within-run CV values below 10%for muscle tissue. The limit of detection was 0.05 mgkg-1.

  17. Preliminary measurement performance evaluation of a new white light interferometer for cylindrical surfaces

    Energy Technology Data Exchange (ETDEWEB)

    Albertazzi, Armando Jr; Pont, Alex Dal [Federal University of Santa Catarina, Metrology and Automation Laboratory, Cx Postal 5053, CEP 88 040-970, Florianopolis, SC (Brazil)

    2005-01-01

    This paper introduces a new design of a white light interferometer, suitable for measurement of cylindrical or quasi-cylindrical parts. A high precision 45 deg. conical mirror is used to direct collimated light radially, making it possible to measure in true cylindrical coordinates. The image of the measurand, distorted by the conical mirror, is projected in a high resolution digital camera. A mapping algorithm is used to reconstruct the cylindrical geometry from the distorted image. The rest of the interferometer is quite similar to a conventional white light interferometer: A flat reference mirror is scanned through the measurement range while an algorithm is searching for the maximum contrast position of the interference pattern. The performance evaluation of a configuration suitable for measurement of external cylindrical surfaces is also presented in this paper. A master cylinder was used as reference. Uncertainties of about 1.0 {mu}m were found at the present stage of development.

  18. Interactive segmentation of plexiform neurofibroma tissue: method and preliminary performance evaluation.

    Science.gov (United States)

    Weizman, Lior; Hoch, Lior; Ben Bashat, Dafna; Joskowicz, Leo; Pratt, Li-tal; Constantini, Shlomi; Ben Sira, Liat

    2012-08-01

    Plexiform neurofibromas (PNs) are a major manifestation of neurofibromatosis-1 (NF1), a common genetic disease involving the nervous system. Treatment decisions are mostly based on a gross assessment of changes in tumor using MRI. Accurate volumetric measurements are rarely performed in this kind of tumors mainly due to its great dispersion, size, and multiple locations. This paper presents a semi-automatic method for segmentation of PN from STIR MRI scans. The method starts with a user-based delineation of the tumor area in a single slice and automatically segments the PN lesions in the entire image based on the tumor connectivity. Experimental results on seven datasets, with lesion volumes in the range of 75-690 ml, yielded a mean absolute volume error of 10 % (after manual adjustment) as compared to manual segmentation by an expert radiologist. The mean computation and interaction time was 13 versus 63 min for manual annotation.

  19. Jumping performance in the highly aquatic frog, Xenopus tropicalis: sex-specific relationships between morphology and performance

    Directory of Open Access Journals (Sweden)

    Anthony Herrel

    2014-11-01

    Full Text Available Frogs are characterized by a morphology that has been suggested to be related to their unique jumping specialization. Yet, the functional demands associated with jumping and swimming may not be that different as suggested by studies with semi-aquatic frogs. Here, we explore whether features previously identified as indicative of good burst swimming performance also predict jumping performance in a highly aquatic frog, Xenopus tropicalis. Moreover, we test whether the morphological determinants of jumping performance are similar in the two sexes and whether jumping performance differs in the two sexes. Finally we test whether jumping capacity is positively associated with burst swimming and terrestrial endurance capacity in both sexes. Our results show sex-specific differences in jumping performance when correcting for differences in body size. Moreover, the features determining jumping performance are different in the two sexes. Finally, the relationships between different performance traits are sex-dependent as well with females, but not males, showing a trade-off between peak jumping force and the time jumped to exhaustion. This suggests that different selective pressures operate on the two sexes, with females being subjected to constraints on locomotion due to their greater body mass and investment in reproductive capacity. In contrast, males appear to invest more in locomotor capacity giving them higher performance for a given body size compared to females.

  20. Preliminary Assessment of a Debris Bed Cooling Performance for Demonstration Sodium-cooled Fast Reactor

    Energy Technology Data Exchange (ETDEWEB)

    Cho, Chung Ho; Park, Chang Gyu; Song, Hoon; Kim, Young Gyun; Jeong, Hae Yong; Chang, Jin Wook [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2012-05-15

    In the case of the sodium-cooled fast reactor such as KALIMER-600, Hypothetical Core Disruptive Accident (HCDA) attributed from mass nuclear fuel melting is unlikely to occur due to defense in depth concepts to meet requirements of redundancy and diversity. Multiple faults such as loss of flow, loss of heat sink, or transient overpower without scram are to lead rising the power level until cladding failure as reactivity increasing. The fact that metallic fuel melts at a lower temperature than the cladding allows significant in-pin- fuel motion to occur prior to cladding failure. Also, the combination of Doppler and axial expansion feedback and negative feedback associated with the in-pin fuel relocation prevents the reactivity from reaching prompt critical. Finally, the resulting reactivity and power reductions help prevent fuel temperatures from rising more than the fuel melting temperature. It is more difficult to occur HCDA in a metallic fueled core because reactor power and heat removal capability is maintained in balance by inherent safety characteristics However, for the future design of sodium-cooled fast reactor, the evaluation of the safety performance and the determination of containment requirements may be worth considering due to the triple-fault accident sequences of extremely low probability of occurrence that leads to core melting. For any postulated accident sequence which leads to core melting, in-vessel retention of the core debris will be required as a design requirement for the future design of sodium cooled fast reactor. Also, proof of the capacity of the debris bed cooling is an essential condition to solve the problem of in-vessel retention of the core debris. Accordingly, evaluation of a packed debris bed cooling performance with single phase flow for demonstration sodium-cooled fast reactor was carried out for proof of the in-vessel retention of the core debris

  1. Performance, cost and environmental assessment of gasification-based electricity in India: A preliminary analysis

    Science.gov (United States)

    Rani, Abha; Singh, Udayan; Jayant; Singh, Ajay K.; Sankar Mahapatra, Siba

    2017-07-01

    Coal gasification processes are crucial to decarbonisation in the power sector. While underground coal gasification (UCG) and integrated gasification combined cycle (IGCC) are different in terms of the site of gasification, they have considerable similarities in terms of the types of gasifiers used. Of course, UCG offers some additional advantages such as reduction of the fugitive methane emissions accompanying the coal mining process. Nevertheless, simulation of IGCC plants involving surface coal gasification is likely to give reasonable indication of the 3E (efficiency, economics and emissions) prospects of the gasification pathway towards electricity. This paper will aim at Estimating 3E impacts (efficiency, environment, economics) of gasification processes using simulation carried out in the Integrated Environmental Control Model (IECM) software framework. Key plant level controls which will be studied in this paper will be based on Indian financial regulations and operating costs which are specific to the country. Also, impacts of CO2 capture and storage (CCS) in these plants will be studied. The various parameters that can be studied are plant load factor, impact of coal quality and price, type of CO2 capture process, capital costs etc. It is hoped that relevant insights into electricity generation from gasification may be obtained with this paper.

  2. Bridging the gap: Research and validation of the DST (Dynamic System Testing) performance test method for CE and ISO standards. Progress and preliminary results

    NARCIS (Netherlands)

    Naron, D.J.; Ree, B.G.C. van der; Rolloos, M.

    1998-01-01

    The Dynamic System Testing (DST) method is one of the methods chosen in the preliminary CEN/TC 312 European quality standards [1 ] to measure the energetic performance of Solar Domestic Hot Water (SDHW) systems. These European standards make a reference to the DST procedure as defined in the Draft I

  3. Preliminary Performance Assessment for the Waste Management Area C at the Hanford Site in Southeast Washington

    Energy Technology Data Exchange (ETDEWEB)

    Bergeron, Marcel P. [Washington River Protection Solutions LLC, Richland, WA (United States); Singleton, Kristin M. [Washington River Protection Solutions LLC, Richland, WA (United States); Eberlein, Susan J. [Washington River Protection Solutions LLC, Richland, WA (United States)

    2015-01-07

    A performance assessment (PA) of Single-Shell Tank (SST) Waste Management Area C (WMA C) located at the U.S. Department of Energy's (DOE) Hanford Site in southeastern Washington is being conducted to satisfy the requirements of the Hanford Federal Facility Agreement and Consent Order (HFFACO), as well as other Federal requirements and State-approved closure plans and permits. The WMP C PA assesses the fate, transport, and impacts of radionuclides and hazardous chemicals within residual wastes left in tanks and ancillary equipment and facilities in their assumed closed configuration and the subsequent risks to humans into the far future. The part of the PA focused on radiological impacts is being developed to meet the requirements for a closure authorization under DOE Order 435.1 that includes a waste incidental to reprocessing determination for residual wastes remaining in tanks, ancillary equipment, and facilities. An additional part of the PA will evaluate human health and environmental impacts from hazardous chemical inventories in residual wastes remaining in WMA C tanks, ancillary equipment, and facilities needed to meet the requirements for permitted closure under RCRA.

  4. Preparation and Preliminary Dialysis Performance Research of Polyvinylidene Fluoride Hollow Fiber Membranes

    Directory of Open Access Journals (Sweden)

    Qinglei Zhang

    2015-03-01

    Full Text Available In this study, the separation properties of Polyvinylidene fluoride (PVDF hollow fiber hemodialysis membranes were improved by optimizing membrane morphology and structure. The results showed that the PVDF membrane had better mechanical and separation properties than Fresenius Polysulfone High-Flux (F60S membrane. The PVDF membrane tensile stress at break, tensile elongation and bursting pressure were 11.3 MPa, 395% and 0.625 MPa, respectively. Ultrafiltration (UF flux of pure water reached 108.2 L∙h−1∙m−2 and rejection of Albumin from bovine serum was 82.3%. The PVDF dialyzers were prepared by centrifugal casting. The influences of membrane area and simulate fluid flow rate on dialysis performance were investigated. The results showed that the clearance rate of urea and Lysozyme (LZM were improved with increasing membrane area and fluid flow rate while the rejection of albumin from bovine serum (BSA had little influence. The high-flux PVDF dialyzer UF coefficient reached 62.6 mL/h/mmHg. The PVDF dialyzer with membrane area 0.69 m2 has the highest clearance rate to LZM and urea. The clearance rate of LZM was 66.8% and urea was 87.7%.

  5. Preliminary Investigation for Engine Performance by Using Tire-Derived Pyrolysis Oil-Diesel Blended Fuels

    Science.gov (United States)

    Rofiqul, Islam M.; Haniu, Hiroyuki; Alam, Beg R.; Takai, Kazunori

    In the first phase of the present study, the pyrolysis oil derived from light automotive tire waste has been characterized including fuel properties, elemental analyses, FT-IR, 1H-NMR, GC-MS and distillation. The studies on the oil show that it can be used as liquid fuel with a gross calorific value (GCV) of 42.00 MJ/kg and empirical formula of CH1.27O0.025N0.006. In the second phase of the investigation, the performance of a diesel engine was studied blending the pyrolysis oil with diesel fuel in different ratios. The experimental results show that the bsfc of pyrolysis oil-diesel blended fuels slightly increases and hence the brake thermal efficiency decreases compared to those of neat diesel. The pyrolysis oil-diesel blends show lower carbon monoxide (CO) emission but higher oxides of nitrogen (NOx) emissions than those of neat diesel. However, NOx emissions with pyrolysis oil-diesel blended fuels reduced when EGR was applied.

  6. Preliminary performance assessment of biotoxin detection for UWS applications using a MicroChemLab device.

    Energy Technology Data Exchange (ETDEWEB)

    VanderNoot, Victoria A.; Haroldsen, Brent L.; Renzi, Ronald F.; Shokair, Isaac R.

    2010-03-01

    In a multiyear research agreement with Tenix Investments Pty. Ltd., Sandia has been developing field deployable technologies for detection of biotoxins in water supply systems. The unattended water sensor or UWS employs microfluidic chip based gel electrophoresis for monitoring biological analytes in a small integrated sensor platform. This instrument collects, prepares, and analyzes water samples in an automated manner. Sample analysis is done using the {mu}ChemLab{trademark} analysis module. This report uses analysis results of two datasets collected using the UWS to estimate performance of the device. The first dataset is made up of samples containing ricin at varying concentrations and is used for assessing instrument response and detection probability. The second dataset is comprised of analyses of water samples collected at a water utility which are used to assess the false positive probability. The analyses of the two sets are used to estimate the Receiver Operating Characteristic or ROC curves for the device at one set of operational and detection algorithm parameters. For these parameters and based on a statistical estimate, the ricin probability of detection is about 0.9 at a concentration of 5 nM for a false positive probability of 1 x 10{sup -6}.

  7. Preliminary evaluation of SensHand V1 in assessing motor skills performance in Parkinson disease.

    Science.gov (United States)

    Cavallo, Filippo; Esposito, Dario; Rovini, Erika; Aquilano, Michela; Carrozza, Maria Chiara; Dario, Paolo; Maremmani, Carlo; Bongioanni, Paolo

    2013-06-01

    Nowadays, the increasing old population 65+ as well as the pace imposed by work activities lead to a high number of people that have particular injuries for limbs. In addition to persistent or temporary disabilities related to accidental injuries we must take into account that part of the population suffers from motor deficits of the hands due to stroke or diseases of various clinical nature. The most recurrent technological solutions to measure the rehabilitation or skill motor performance of the hand are glove-based devices, able to faithfully capture the movements of the hand and fingers. This paper presents a system for hand motion analysis based on 9-axis complete inertial modules and dedicated microcontroller which are fixed on fingers and forearm. The technological solution presented is able to track the patients' hand motions in real-time and then to send data through wireless communication reducing the clutter and the disadvantages of a glove equipped with sensors through a different technological structure. The device proposed has been tested in the study of Parkinson's disease.

  8. A preliminary study on anti-irradiation performance of epoxy shape memory polymer

    Science.gov (United States)

    Wu, Xuelian; Liu, Yanju; Leng, Jinsong

    2009-07-01

    As a new class of smart material, shape memory polymer (SMP) receives more and more attention. In this paper, in addition to the fabrication of a new type of epoxy SMP, the thermo-mechanical properties of the polymer with/without gamma irradiation were investigated and compared systematically. The radiation source is Co-60 and the total dosage of radiation is 1×104Gy. Changes of network structures of the polymer were investigated by Fourier Transform Infrared (FTIR) spectroscopy. The influence of gamma irradiation on thermo and mechanical properties of the polymer were investigated by Differential Scanning Calorimetry (DSC), Dynamic Mechanical Analysis (DMA) and tensile test, respectively. Furthermore, shape recovery behaviors of the polymer before/after the irradiation were compared too. Results show that the epoxy SMP possesses good chemical stability, glass transition temperature (Tg) determined by DSC decreased by 7°C after the irradiation. The gamma radiation has a slight influence on storage modulus, loss modulus and tan delta, respectively. No considerable change was found both in tensile strength and elongation at break after the gamma radiation. Finally, the shape recovery ratio of the polymer is near 100% with and without the gamma irradiation. Based on the above results, it can be demonstrated that the epoxy SMP prepared in the study possesses not only good thermo-mechanical properties but unique anti irradiation performance. The epoxy SMP shows potential for application of aerospace fields.

  9. Specifications and Performances of Series Superfluid Helium Safety Relief Valves for the LHC

    Science.gov (United States)

    Perin, A.; Fontanive, V.

    2006-04-01

    Protecting the LHC magnets requires safety relief valves operating with 1.9 K pressurized superfluid helium at their inlet. Following the evaluation of prototype valves, a specification for the production of the 360 safety relief valves needed for the LHC was issued. The production of the safety valves was then awarded to an industrial contractor. The performances of pre-series valves were assessed for a variety of aspects including thermal performance, leak tightness in superfluid helium, dynamic behavior and resistance to intensive mechanical cycling. After the initial validation phase the series production was completed within the technical requirements of the specification. This paper describes the characteristics of the safety relief valves and the specifications for their industrial production. The performances of the pre-series valves are presented and an overview of the series production phase is given.

  10. Crystallization and preliminary X-ray crystallographic analysis of a highly specific serpin from the beetle Tenebrio molitor.

    Science.gov (United States)

    Park, Sun Hee; Piao, Shunfu; Kwon, Hyun Mi; Kim, Eun Hye; Lee, Bok Luel; Ha, Nam Chul

    2010-02-01

    The Toll signalling pathway, which is crucial for innate immunity, is transduced in insect haemolymph via a proteolytic cascade consisting of three serine proteases. The proteolytic cascade is downregulated by a specific serine protease inhibitor (serpin). Recently, the serpin SPN48 was found to show an unusual specific reactivity towards the terminal serine protease, Spätzle-processing enzyme, in the beetle Tenebrio molitor. In this study, the mature form of SPN48 was overexpressed in Escherichia coli and purified. The purified SPN48 protein was crystallized using 14% polyethylene glycol 8000 and 0.1 M 2-(N-morpholino)ethanesulfonic acid pH 6.0 as the precipitant. The crystals diffracted X-rays to 2.1 A resolution and were suitable for structure determination. The crystals belonged to space group P2(1). The crystal structure will provide information regarding how SPN48 achieves its unusual specificity for its target protease.

  11. Ensuring performance by geometric quality control and specifications for parabolic trough solar fields

    OpenAIRE

    Pottler, Klaus; Ulmer, Steffen; Lüpfert, Eckhard; Landmann, Martin; Röger, Marc; Prahl, Christoph

    2014-01-01

    Solar field thermal output depends on the optical, geometrical and thermal parameters of the installed solar collectors. In addition to appropriate collector design and quality of the components, proper assembly and installation processes are most relevant for high performance. Target values for the intercept factor are in the range of 96-99% for typical operating conditions. These values can only be reached if appropriate quality specifications are fulfilled. Specification values are suggest...

  12. Performance of pond-wetland complexes as a preliminary processor of drinking water sources.

    Science.gov (United States)

    Wang, Weidong; Zheng, Jun; Wang, Zhongqiong; Zhang, Rongbin; Chen, Qinghua; Yu, Xinfeng; Yin, Chengqing

    2016-01-01

    Shijiuyang Constructed Wetland (110 hm(2)) is a drinking water source treatment wetland with primary structural units of ponds and plant-bed/ditch systems. The wetland can process about 250,000 tonnes of source water in the Xincheng River every day and supplies raw water for Shijiuyang Drinking Water Plant. Daily data for 28 months indicated that the major water quality indexes of source water had been improved by one grade. The percentage increase for dissolved oxygen and the removal rates of ammonia nitrogen, iron and manganese were 73.63%, 38.86%, 35.64%, and 22.14% respectively. The treatment performance weight of ponds and plant-bed/ditch systems was roughly equal but they treated different pollutants preferentially. Most water quality indexes had better treatment efficacy with increasing temperature and inlet concentrations. These results revealed that the pond-wetland complexes exhibited strong buffering capacity for source water quality improvement. The treatment cost of Shijiuyang Drinking Water Plant was reduced by about 30.3%. Regional rainfall significantly determined the external river water levels and adversely deteriorated the inlet water quality, thus suggesting that the "hidden" diffuse pollution in the multitudinous stream branches as well as their catchments should be the controlling emphases for river source water protection in the future. The combination of pond and plant-bed/ditch systems provides a successful paradigm for drinking water source pretreatment. Three other drinking water source treatment wetlands with ponds and plant-bed/ditch systems are in operation or construction in the stream networks of the Yangtze River Delta and more people will be benefited.

  13. Evaluation of atmospheric density models and preliminary functional specifications for the Langley Atmospheric Information Retrieval System (LAIRS)

    Science.gov (United States)

    Lee, T.; Boland, D. F., Jr.

    1980-01-01

    This document presents the results of an extensive survey and comparative evaluation of current atmosphere and wind models for inclusion in the Langley Atmospheric Information Retrieval System (LAIRS). It includes recommended models for use in LAIRS, estimated accuracies for the recommended models, and functional specifications for the development of LAIRS.

  14. Speech and pause characteristics in multiple sclerosis: A preliminary study of speakers with high and low neuropsychological test performance

    Science.gov (United States)

    FEENAUGHTY, LYNDA; TJADEN, KRIS; BENEDICT, RALPH H.B.; WEINSTOCK-GUTTMAN, BIANCA

    2017-01-01

    This preliminary study investigated how cognitive-linguistic status in multiple sclerosis (MS) is reflected in two speech tasks (i.e. oral reading, narrative) that differ in cognitive-linguistic demand. Twenty individuals with MS were selected to comprise High and Low performance groups based on clinical tests of executive function and information processing speed and efficiency. Ten healthy controls were included for comparison. Speech samples were audio-recorded and measures of global speech timing were obtained. Results indicated predicted differences in global speech timing (i.e. speech rate and pause characteristics) for speech tasks differing in cognitive-linguistic demand, but the magnitude of these task-related differences was similar for all speaker groups. Findings suggest that assumptions concerning the cognitive-linguistic demands of reading aloud as compared to spontaneous speech may need to be re-considered for individuals with cognitive impairment. Qualitative trends suggest that additional studies investigating the association between cognitive-linguistic and speech motor variables in MS are warranted. PMID:23294227

  15. General Intelligence and Modality-specific Differences in Performance: A Response to Schellenberg (2008

    Directory of Open Access Journals (Sweden)

    Adam T. Tierney

    2009-04-01

    Full Text Available Tierney et al. (2008 reported that musicians performed better on an auditory sequence memory task when compared to non-musicians, but the two groups did not differ in performance on a sequential visuo-spatial memory task. Schellenberg (2008 claims that these results can be attributed entirely to differences in IQ. This explanation, however, cannot account for the fact that the musicians’ advantage was modality-specific.

  16. Firm-specific Factors, Shareholding Structure and Corporate Performance of the Japanese manufacturing Investments in Europe

    OpenAIRE

    MOURAD, MANSOUR; Yasuo, Hoshino; University of Tsukuba

    2000-01-01

    Direct investment by Japanese firms into European manufacturing industries increased substantially during the 1980s. What determines the performance of overseas operations of Multinational enterprises has been an important topic of research. This study aims at providing further evidence on the influence of entry mode and firm specific factors on the performance of Japanese-affiliated manufacturing investments in Europe, based on data for the period 1994-1997 compiled from Toyo Keizai Database...

  17. Visual tracking speed is related to basketball-specific measures of performance in NBA players.

    Science.gov (United States)

    Mangine, Gerald T; Hoffman, Jay R; Wells, Adam J; Gonzalez, Adam M; Rogowski, Joseph P; Townsend, Jeremy R; Jajtner, Adam R; Beyer, Kyle S; Bohner, Jonathan D; Pruna, Gabriel J; Fragala, Maren S; Stout, Jeffrey R

    2014-09-01

    The purpose of this study was to determine the relationship between visual tracking speed (VTS) and reaction time (RT) on basketball-specific measures of performance. Twelve professional basketball players were tested before the 2012-13 season. Visual tracking speed was obtained from 1 core session (20 trials) of the multiple object tracking test, whereas RT was measured by fixed- and variable-region choice reaction tests, using a light-based testing device. Performance in VTS and RT was compared with basketball-specific measures of performance (assists [AST]; turnovers [TO]; assist-to-turnover ratio [AST/TO]; steals [STL]) during the regular basketball season. All performance measures were reported per 100 minutes played. Performance differences between backcourt (guards; n = 5) and frontcourt (forward/centers; n = 7) positions were also examined. Relationships were most likely present between VTS and AST (r = 0.78; p basketball-specific performance measures. Backcourt players were most likely to outperform frontcourt players in AST and very likely to do so for VTS, TO, and AST/TO. In conclusion, VTS seems to be related to a basketball player's ability to see and respond to various stimuli on the basketball court that results in more positive plays as reflected by greater number of AST and STL and lower turnovers.

  18. The impact of specific motoricity on karate performance in young karateka.

    Science.gov (United States)

    Katić, Ratko; Jukić, Jozefina; Glavan, Ivan; Ivanisević, Snjezana; Gudelj, Ines

    2009-03-01

    The aim of the study was to assess interdependence of specific motor abilities (situation karate tests) and motor skills (karate techniques), and karate performance (fighting efficiency) in under-sixteen male karateka aged 11-12 and 13-14 years. A battery of 5 situation motor tests were applied and 6 basic elements of karate technique evaluated in a sample of 20 male karateka aged 11-12 and 20 male karateka aged 13-14 years. Three criterion variables were formed: 1) one factor as a factor of general technical efficiency in karate was isolated by factor analysis of 6 karate techniques; 2) cumulative evaluation of 2 kate as kate performance; and 3) total score assessment based on success achieved at national karate championships as contest efficiency (fighting efficiency). Regression analysis revealed the frequency of gedan barai blockade performance to be the superior predictor of technical efficiency, kate performance and contest success in karateka aged 11-12, whereas the speed of the gedan barai-jaku zuki (block-kick) combination performance and specific agility (sidewise mobility) were superior predictors of performance in karateka aged 13-14. Of the karate techniques (kicks) used, the quality of jaku zuki kick performance was the superior predictor of contest efficiency in karateka aged 11-12, and the quality of the jaku zuki-mawashi geri and kizame zuki-jaku zuki combination performance in karateka aged 13-14.

  19. Purification, crystallization and preliminary crystallographic analysis of Est25: a ketoprofen-specific hormone-sensitive lipase

    Energy Technology Data Exchange (ETDEWEB)

    Kim, SeungBum [Department of Biological and Molecular Engineering, College of Engineering, Ajou University, Suwon (Korea, Republic of); Joo, Sangbum [Department of Molecular Cell Biology, Sungkyunkwan University School of Medicine, Suwon (Korea, Republic of); Yoon, Hyun C.; Ryu, Yeonwoo [Department of Biological and Molecular Engineering, College of Engineering, Ajou University, Suwon (Korea, Republic of); Kim, Kyeong Kyu, E-mail: kkim@med.skku.ac.kr [Department of Molecular Cell Biology, Sungkyunkwan University School of Medicine, Suwon (Korea, Republic of); Kim, T. Doohun, E-mail: kkim@med.skku.ac.kr [Department of Biological and Molecular Engineering, College of Engineering, Ajou University, Suwon (Korea, Republic of)

    2007-07-01

    Est25, a ketoprofen-specific hormone-sensitive lipase from a metagenomic library, was crystallized and diffraction data were collected to 1.49 Å resolution. Ketoprofen, a nonsteroidal anti-inflammatory drug, inhibits the synthesis of prostaglandin. A novel hydrolase (Est25) with high ketoprofen specificity has previously been identified using a metagenomic library from environmental samples. Recombinant Est25 protein with a histidine tag at the N-terminus was expressed in Escherichia coli and purified in a homogenous form. Est25 was crystallized from 2.4 M sodium malonate pH 7.0 and X-ray diffraction data were collected to 1.49 Å using synchrotron radiation. The crystals belong to the monoclinic space group C2, with unit-cell parameters a = 197.8, b = 95.2, c = 99.4 Å, β = 97.1°.

  20. Utility of craniosacral therapy in treatment of patients with non-specific low back pain. Preliminary report.

    Science.gov (United States)

    Białoszewski, Dariusz; Bebelski, Marcin; Lewandowska, Monika; Słupik, Anna

    2014-01-01

    Non-specific low back pain is an increasingly common musculoskeletal ailment. The aim of this study was to examine the utility of craniosacral therapy techniques in the treatment of patients with lumbosacral spine overload and to compare its effectiveness to that of trigger point therapy, which is a recognised therapeutic approach. The study enrolled 55 randomly selected patients (aged 24-47 years) with low back pain due to overload. Other causes of this condition in the patients were ruled out. The participants were again randomly assigned to two groups: patients treated with craniosacral therapy (G-CST) and patients treated with trigger point therapy (G-TPT). Multiple aspects of the effectiveness of both therapies were evaluated with the use of: an analogue scale for pain (VAS) and a modified Laitinen questionnaire, the Schober test and surface electromyography of the multifidus muscle. The statistical analysis of the outcomes was based on the basic statistics, the Mann-Whitney U test and Wilcoxon's signed rank test. The statistical significance level was set at p≤0.05. Both groups demonstrated a significant reduction of pain measured with the VAS scale and the Laitinen questionnaire. Moreover, the resting bioelectric activity of the multifidus muscle decreased significantly in the G-CST group. The groups did not differ significantly with regard to the study parameters. 1. Craniosacral therapy and trigger point therapy may effectively reduce the intensity and frequency of pain in patients with non-specific low back pain. 2. Craniosacral therapy, unlike trigger point therapy, reduces the resting tension of the multifidus muscle in patients with non-specific lumbosacral pain. The mechanism of these changes requires further research. 3. Craniosacral therapy and trigger point therapy may be clinically effective in the treatment of patients with non-specific lumbosacral spine pain. 4. The present findings represent a basis for conducting further and prospective

  1. Autism-specific covariation in perceptual performances: "g" or "p" factor?

    Directory of Open Access Journals (Sweden)

    Andrée-Anne S Meilleur

    Full Text Available BACKGROUND: Autistic perception is characterized by atypical and sometimes exceptional performance in several low- (e.g., discrimination and mid-level (e.g., pattern matching tasks in both visual and auditory domains. A factor that specifically affects perceptive abilities in autistic individuals should manifest as an autism-specific association between perceptual tasks. The first purpose of this study was to explore how perceptual performances are associated within or across processing levels and/or modalities. The second purpose was to determine if general intelligence, the major factor that accounts for covariation in task performances in non-autistic individuals, equally controls perceptual abilities in autistic individuals. METHODS: We asked 46 autistic individuals and 46 typically developing controls to perform four tasks measuring low- or mid-level visual or auditory processing. Intelligence was measured with the Wechsler's Intelligence Scale (FSIQ and Raven Progressive Matrices (RPM. We conducted linear regression models to compare task performances between groups and patterns of covariation between tasks. The addition of either Wechsler's FSIQ or RPM in the regression models controlled for the effects of intelligence. RESULTS: In typically developing individuals, most perceptual tasks were associated with intelligence measured either by RPM or Wechsler FSIQ. The residual covariation between unimodal tasks, i.e. covariation not explained by intelligence, could be explained by a modality-specific factor. In the autistic group, residual covariation revealed the presence of a plurimodal factor specific to autism. CONCLUSIONS: Autistic individuals show exceptional performance in some perceptual tasks. Here, we demonstrate the existence of specific, plurimodal covariation that does not dependent on general intelligence (or "g" factor. Instead, this residual covariation is accounted for by a common perceptual process (or "p" factor, which may

  2. Physiological and performance effects of generic versus specific aerobic training in soccer players.

    Science.gov (United States)

    Impellizzeri, F M; Marcora, S M; Castagna, C; Reilly, T; Sassi, A; Iaia, F M; Rampinini, E

    2006-06-01

    The aim of this study was to compare the effects of specific (small-sided games) vs. generic (running) aerobic interval training on physical fitness and objective measures of match performance in soccer. Forty junior players were randomly assigned to either generic (n=20) or specific (n=20) interval training consisting of 4 bouts of 4 min at 90-95 % of maximum heart rate with 3 min active rest periods, completed twice a week. The following outcomes were measured at baseline (Pre), after 4 weeks of pre-season training (Mid), and after a further 8 weeks of training during the regular season (Post): maximum oxygen uptake, lactate threshold (Tlac), running economy at Tlac, a soccer-specific endurance test (Ekblom's circuit), and indices of physical performance during soccer matches (total distance and time spent standing, walking, and at low- and high-intensity running speed). Training load, as quantified by heart rate and rating of perceived exertion, was recorded during all training sessions and was similar between groups. There were significant improvements in aerobic fitness and match performance in both groups of soccer players, especially in response to the first 4 weeks of pre-season training. However, no significant differences between specific and generic aerobic interval training were found in any of the measured variables including soccer specific tests. The results of this study showed that both small-sided games and running are equally effective modes of aerobic interval training in junior soccer players.

  3. The Effect of Instrument-Specific Rater Training on Interrater Reliability and Counseling Skills Performance Differentiation

    Science.gov (United States)

    Meacham, Paul Douglas, Jr.

    2013-01-01

    The purpose of this study was to explore the effect of instrument-specific rater training on interrater reliability (IRR) and counseling skills performance differentiation. Strong IRR is of primary concern to effective program evaluation (McCullough, Kuhn, Andrews, Valen, Hatch, & Osimo, 2003; Schanche, Nielsen, McCullough, Valen, &…

  4. Constructing Domain-Specific Knowledge in Kindergarten: Relations among Knowledge, Intelligence, and Strategic Performance

    Science.gov (United States)

    Alexander, Joyce M.; Johnson, Kathy E.; Leibham, Mary E.; DeBauge, Christiane

    2005-01-01

    Thirty kindergarten children from two classrooms participated in a 3-week curricular unit on dinosaurs designed to teach taxonomic relations and distinguishing features aligned with 15 dinosaur species. Both domain-specific learning and strategic performance on a Twenty Questions game were assessed twice throughout the curriculum, as well as…

  5. General and Domain-Specific Contributions to Creative Ideation and Creative Performance

    Directory of Open Access Journals (Sweden)

    Donggun An

    2016-11-01

    Full Text Available The general objective of this study was to reexamine two views of creativity, one positing that there is a general creative capacity or talent and the other that creativity is domain-specific. These two views were compared by (a testing correlations among measures of domain-general and domain-specific creativity and (b examining how the general and the specific measures was each related to indices of knowledge, motivation, and personality. Participants were 147 college students enrolled in a foreign language course. Data were collected on participants’ domain knowledge, motivation, and creative personality, as well as four measures representing “General or Domain-Specific Creative Ideation” or “Creative Performance and Activity”. Results indicated that the four measures of creativity were correlated with one another, except for “General Performance and Activity” and “Domain-Specific Ideation.” A canonical correlation indicated that knowledge, motivation, and personality were significantly correlated with the four creativity measures (Rc = .49, p < .01. Multiple regressions uncovered particular relationships consistent with the view that creativity has both general and domain-specific contributions. Limitations, such as the focus on one domain, and future directions are discussed.

  6. SOME SPECIFIC FEATURES OF THE DIAGNOSIS AND TREATMENT OF KIDNEY CANCER IN RUSSIA: PRELIMINARY RESULTS OF A MULTICENTER COOPERATIVE STUDY

    Directory of Open Access Journals (Sweden)

    B. Ya. Alekseev

    2014-08-01

    Full Text Available An interim analysis of the database comprising information on 7813 kidney cancer (KC patients who had been treated or followed up in 25 health care facilities of Russia yielded some patient characteristics, the specific features of the tumor process, and main approaches to surgical and medical treatments. Such characteristics as a male-to-female patient ratio, stage distribution in patients, detection rate of different histological types of KC and different tumor grades, proportion of organ-saving and organ-removing interventions, drug treatments for metastatic KC are considered.

  7. SOME SPECIFIC FEATURES OF THE DIAGNOSIS AND TREATMENT OF KIDNEY CANCER IN RUSSIA: PRELIMINARY RESULTS OF A MULTICENTER COOPERATIVE STUDY

    Directory of Open Access Journals (Sweden)

    B. Ya. Alekseev

    2012-01-01

    Full Text Available An interim analysis of the database comprising information on 7813 kidney cancer (KC patients who had been treated or followed up in 25 health care facilities of Russia yielded some patient characteristics, the specific features of the tumor process, and main approaches to surgical and medical treatments. Such characteristics as a male-to-female patient ratio, stage distribution in patients, detection rate of different histological types of KC and different tumor grades, proportion of organ-saving and organ-removing interventions, drug treatments for metastatic KC are considered.

  8. The Role of Self-Efficacy in Inflammatory Bowel Disease Management: Preliminary Validation of a Disease-Specific Measure

    OpenAIRE

    2011-01-01

    IBDs require self-management skills that may be influenced by self-efficacy (SE). Self Efficacy represents an individual’s perception of his or her ability to organize and execute the behaviors necessary to manage disease. The goal of this study was to develop a valid and reliable measure of IBD-specific SE that can be used in clinical and research contexts. 122 adults with a verified IBD diagnosis participated in the study. Data were pooled from two sources: patients from an outpatient unive...

  9. A methodology for performance specifications and guarantees to reconcile owner/contractor criteria

    Energy Technology Data Exchange (ETDEWEB)

    Ahner, D.J.; Priestley, R.R. [Power Technologies, Inc., Schenectady, NY (United States)

    1996-05-01

    The performance objectives of a plant owner and the turnkey contractor may not generally be compatible or represent the same levels of acceptable risk for a given application. The owner is concerned that the plant has a high performance level that contributes to a high probability of meeting acceptable financial return goals. The contractor is concerned with demonstrating a plant performance that meets the guarantees with an acceptable level of risk. The economic incentives and competitive environment introduce influences which can negatively impact performance margins and increase the owners and contractor`s risk levels to secure a positive evaluation In advantage. Ibis paper discusses these owner/contractor objectives and develops a methodology to identify regions of compatibility and conflict to the performance specification. The objectives and risk thresholds are quantified in terms of risk or probability of meeting specific performance goals for each party. The effects and influence of key parameters such as guarantee margins, performance variability and test quality is illustrated by application examples.

  10. Crystallization and preliminary X-ray crystallographic analysis of the tRNA-specific adenosine deaminase from Streptococcus pyogenes

    Energy Technology Data Exchange (ETDEWEB)

    Ku, Min-Je [Functional Proteomics Center, Korea Institute of Science and Technology, 39-1 Hawolgok-dong, Seongbuk-gu, Seoul 136-791 (Korea, Republic of); Lee, Won-Ho [Functional Proteomics Center, Korea Institute of Science and Technology, 39-1 Hawolgok-dong, Seongbuk-gu, Seoul 136-791 (Korea, Republic of); Biotechnology and Genetic Engineering, Korea University, Seoul 136-701 (Korea, Republic of); Nam, Ki-hyun; Rhee, Kyeong-hee [Biomedical Research Center, Life Science Division, Korea Institute of Science and Technology, 39-1 Hawolgok-dong, Seongbuk-gu, Seoul 136-791 (Korea, Republic of); Lee, Ki-Seog [Biotechnology and Genetic Engineering, Korea University, Seoul 136-701 (Korea, Republic of); Kim, Eunice EunKyung [Biomedical Research Center, Life Science Division, Korea Institute of Science and Technology, 39-1 Hawolgok-dong, Seongbuk-gu, Seoul 136-791 (Korea, Republic of); Yu, Myung-Hee [Functional Proteomics Center, Korea Institute of Science and Technology, 39-1 Hawolgok-dong, Seongbuk-gu, Seoul 136-791 (Korea, Republic of); Hwang, Kwang Yeon, E-mail: hwangky@kist.re.kr [Biomedical Research Center, Life Science Division, Korea Institute of Science and Technology, 39-1 Hawolgok-dong, Seongbuk-gu, Seoul 136-791 (Korea, Republic of); Functional Proteomics Center, Korea Institute of Science and Technology, 39-1 Hawolgok-dong, Seongbuk-gu, Seoul 136-791 (Korea, Republic of)

    2005-04-01

    The tRNA-specific adenosine deaminase from the pathogenic bacteria S. pyogenes has been overexpressed and crystallized. The tRNA-specific adenosine deaminase from the pathogenic bacteria Streptococcus pyogenes (spTAD) has been overexpressed in Escherichia coli and crystallized in the presence of Zn{sup 2+} ion at 295 K using ammonium sulfate as a precipitant. Flash-cooled crystals of spTAD diffracted to 2.0 Å using 30%(v/v) glycerol as a cryoprotectant. X-ray diffraction data have been collected to 2.0 Å using synchrotron radiation. The crystal belongs to the tetragonal space group P4{sub 2}2{sub 1}2, with unit-cell parameters a = b = 81.042, c = 81.270 Å. The asymmetric unit contains one subunit of spTAD, with a corresponding crystal volume per protein weight (V{sub M}) of 3.3 Å{sup 3} Da{sup −1} and a solvent content of 62.7%.

  11. Preliminary performance assessment for the Waste Isolation Pilot Plant, December 1992. Volume 5, Uncertainty and sensitivity analyses of gas and brine migration for undisturbed performance

    Energy Technology Data Exchange (ETDEWEB)

    1993-08-01

    Before disposing of transuranic radioactive waste in the Waste Isolation Pilot Plant (WIPP), the United States Department of Energy (DOE) must evaluate compliance with applicable long-term regulations of the United States Environmental Protection Agency (EPA). Sandia National Laboratories is conducting iterative performance assessments (PAs) of the WIPP for the DOE to provide interim guidance while preparing for a final compliance evaluation. This volume of the 1992 PA contains results of uncertainty and sensitivity analyses with respect to migration of gas and brine from the undisturbed repository. Additional information about the 1992 PA is provided in other volumes. Volume 1 contains an overview of WIPP PA and results of a preliminary comparison with 40 CFR 191, Subpart B. Volume 2 describes the technical basis for the performance assessment, including descriptions of the linked computational models used in the Monte Carlo analyses. Volume 3 contains the reference data base and values for input parameters used in consequence and probability modeling. Volume 4 contains uncertainty and sensitivity analyses with respect to the EPA`s Environmental Standards for the Management and Disposal of Spent Nuclear Fuel, High-Level and Transuranic Radioactive Wastes (40 CFR 191, Subpart B). Finally, guidance derived from the entire 1992 PA is presented in Volume 6. Results of the 1992 uncertainty and sensitivity analyses indicate that, conditional on the modeling assumptions and the assigned parameter-value distributions, the most important parameters for which uncertainty has the potential to affect gas and brine migration from the undisturbed repository are: initial liquid saturation in the waste, anhydrite permeability, biodegradation-reaction stoichiometry, gas-generation rates for both corrosion and biodegradation under inundated conditions, and the permeability of the long-term shaft seal.

  12. Preliminary study of the specific endothelin a receptor antagonist zibotentan in combination with docetaxel in patients with metastatic castration-resistant prostate cancer.

    Science.gov (United States)

    Trump, Donald L; Payne, Heather; Miller, Kurt; de Bono, Johann S; Stephenson, Joe; Burris, Howard A; Nathan, Faith; Taboada, Maria; Morris, Thomas; Hubner, Andreas

    2011-09-01

    This two-part study assessed the safety and tolerability of combined treatment with zibotentan (ZD4054), a specific endothelin A receptor antagonist, plus docetaxel in patients with metastatic castration-resistant prostate cancer. Part A was an open-label, dose-finding phase to determine the safety and toxicity profile of zibotentan in combination with docetaxel. Patients received once-daily oral zibotentan 10 mg (initial cohort) or 15 mg in combination with docetaxel 75 mg/m(2) (administered on day 1 of each 21-day cycle) for up to 10 cycles. Part B was a double-blind phase which evaluated the safety and preliminary activity of zibotentan plus docetaxel. Patients were randomized 2:1 to receive zibotentan (at the highest tolerated dose identified in part A) plus docetaxel or placebo plus docetaxel. Six patients were enrolled in part A (n  = 3, zibotentan 10 mg; n = 3, zibotentan 15 mg). No dose-limiting toxicity was observed, thus zibotentan 15 mg in combination with docetaxel was evaluated in part B (n = 20, zibotentan plus docetaxel; n = 11, placebo plus docetaxel). CTCAE grade ≥3, most commonly neutropenia or leucopenia, were reported in 10 (50%) and nine (82%) patients in the zibotentan and placebo groups, respectively. One (17%) patient receiving placebo achieved complete response, two (22%) patients receiving zibotentan achieved partial response and stable disease occurred in six (67%) and three (50%) patients receiving zibotentan and placebo, respectively. The tolerability of zibotentan plus docetaxel was consistent with the known profiles of each drug. Sufficient preliminary activity was seen with this combination to merit continued development. Copyright © 2011 Wiley-Liss, Inc.

  13. Prostate-specific membrane antigen PET imaging and immunohistochemistry in adenoid cystic carcinoma-a preliminary analysis.

    Science.gov (United States)

    Klein Nulent, Thomas J W; van Es, Robert J J; Krijger, Gerard C; de Bree, Remco; Willems, Stefan M; de Keizer, Bart

    2017-09-01

    Adenoid cystic carcinoma (AdCC) of the head and neck is an uncommon malignant epithelial tumour of the secretory glands. Many patients develop slowly growing local recurrence and/or distant metastasis, for which treatment options are limited. A retrospective analysis of 9 AdCC patients was conducted to analyse the visualization of AdCC on PSMA PET/CT and to investigate the expression of PSMA on primary, recurrent and metastatic AdCC tumour tissue using immunohistochemistry. Local recurrence occurred in six patients and eight developed distant metastasis. All PET/CTs depicted PSMA-ligand uptake. Four PSMA PET/CTs showed suspected residual disease, eight scans depicted uptake in areas suspected of distant metastasis. Median Maximum Standardized Uptake Value (SUVmax) in local recurrent and distant metastatic AdCC was 2.52 (IQR 2.41-5.95) and 4.01 (IQR 2.66-8.71), respectively. All primary tumours showed PSMA expression on immunohistochemistry (5-90% expression), as well as all available specimens of local recurrence and distant metastases. PSMA PET/CT is able to detect and visualize local recurrent and distant metastatic AdCC. PSMA-specific targeting is supported by PSMA expression on immunohistochemistry.

  14. Comparison of specific production performances by two crystalline silicon PV systems

    Directory of Open Access Journals (Sweden)

    Martin Fajman

    2013-01-01

    Full Text Available A comparison of two independent photovoltaic (PV systems located close to each other on the south of the Czech Moravian Highland was accomplished. Due to differences in installation parameters; reference quantities were used to calculate transformed data sets for specific production performances comparison. Differences in monthly and annually daily production were performed by t-test.According to obtained results, it was concluded that annually mean daily productions per 1 kWp of installed capacity and per 1 m2 of active area of the panels are significantly better by single crystal silicon installation in tracking system than by stable installation of a different technology of single crystal silicon. However, comparing this performance per 1 m2 of occupied land by studied power-plants the stable installation performed higher production rates on daily mean basis in majority of months of the year 2010 as well as by annually mean daily production.

  15. Gender differences in colour naming performance for gender specific body shape images.

    Science.gov (United States)

    Elliman, N A; Green, M W; Wan, W K

    1998-03-01

    Males are increasingly subjected to pressures to conform to aesthetic body stereotypes. There is, however, comparatively little published research on the aetiology of male body shape concerns. Two experiments are presented, which investigate the relationship between gender specific body shape concerns and colour-naming performance. Each study comprised a between subject design, in which each subject was tested on a single occasion. A pictorial version of a modified Stroop task was used in both studies. Subjects colour-named gender specific obese and thin body shape images and semantically homogeneous neutral images (birds) presented in a blocked format. The first experiment investigated female subjects (N = 68) and the second investigated males (N = 56). Subjects also completed a self-report measure of eating behaviour. Currently dieting female subjects exhibited significant colour-naming differences between obese and neutral images. A similar pattern of colour-naming performance was found to be related to external eating in the male subjects.

  16. EFFECTS OF A CARBOHYDRATE-ELECTROLYTE DRINK ON SPECIFIC SOCCER TESTS AND PERFORMANCE

    Directory of Open Access Journals (Sweden)

    Sergej M. Ostojic

    2002-06-01

    Full Text Available The aim of this study was to examine the effects of a carbohydrate-electrolyte drink on specific soccer tests and performance. Twenty-two professional male soccer players volunteered to participate in the study. The players were allocated to two assigned trials ingesting carbohydrate-electrolyte drink (7% carbohydrates, sodium 24 mmol.l-1, chloride 12 mmol.l-1, potassium 3 mmol.l-1 or placebo during a 90 min on-field soccer match. The trials were matched for subjects' age, weight, height and maximal oxygen uptake. Immediately after the match, players completed four soccer-specific skill tests. Blood glucose concentration [mean (SD] was higher at the end of the match-play in the carbohydrate-electrolyte trial than in the placebo trial (4.4 (0.3 vs. 4.0 (0.3 mmol.l-1, P < 0.05. Subjects in the carbohydrate-electrolyte trial finished the specific dribble test faster in comparison with subjects in the placebo trial (12.9 (0.4 vs. 13.6 (0.5 s, P < 0.05. Ratings of the precision test were higher in the carbohydrate-electrolyte trial as compared to the placebo trial (17.2 (4.8 vs. 15.1 (5.2, P < 0.05 but there were no differences in coordination test and power test results between trials. The main finding of the present study indicates that supplementation with carbohydrate-electrolyte solution improved soccer-specific skill performance and recovery after an on-field soccer match compared with ingestion of placebo. This suggests that soccer players should consume carbohydrate-electrolyte fluid throughout a game to help prevent deterioration in specific skill performance

  17. THE IMPORTANCE OF A SPECIFIC WARM-UP ON THE PERFORMANCE OF THE HANDBALL GOALKEEPER

    Directory of Open Access Journals (Sweden)

    Delia Carmen Dumitru

    2010-08-01

    Full Text Available The aim of this paper is to determine the influence of a specific warm-up in the performance of the handball goalkeeper. To achieve this, the different aspects that influence the preparation of the player who occuppies this position, were examined. The samples chosen for this research consist of five handball playersaged between 17 and 28 years (M = 23 belonging to a Spanish female handball Club. The information was collected from the official match statistics of the first and second national Spanish League. The results obtained point to the need for a specific warm-up for the goalkeeper position because it significantly increases theperformance level of the player in this position, and shows the importance of the specific warm-up for the goalkeeper on the team results.

  18. Towards more complete specifications for acceptable analytical performance - a plea for error grid analysis.

    Science.gov (United States)

    Krouwer, Jan S; Cembrowski, George S

    2011-07-01

    Abstract We examine limitations of common analytical performance specifications for quantitative assays. Specifications can be either clinical or regulatory. Problems with current specifications include specifying limits for only 95% of the results, having only one set of limits that demarcate no harm from minor harm, using incomplete models for total error, not accounting for the potential of user error, and not supplying sufficient protocol requirements. Error grids are recommended to address these problems as error grids account for 100% of the data and stratify errors into different severity categories. Total error estimation from a method comparison can be used to estimate the inner region of an error grid, but the outer region needs to be addressed using risk management techniques. The risk management steps, foreign to many in laboratory medicine, are outlined.

  19. The use of Element-Specific Detectors Coupled with High-Performance Liquid Chromatographs.

    Science.gov (United States)

    1981-11-04

    approach to determining the amount of various chelating agents in solution, Jones and Manahan reacted the indicator metal, A 20 copper(II) with a...latter two cases, GFAA was employed as the element specific detector. Jones and Manahan employing a high performance absorption column directly...Chromatogr. Sci., 17: 395 (1979). 35. D. R. Jones, IV and S. E. Manahan , Anal. Chem., 48: 1897 (1976). 36. D. R. Jones, IV and S. E. Manahan , Anal. Chem

  20. Performance specifications for technology development: Application for characterization of volatile organic compounds in the environment

    Energy Technology Data Exchange (ETDEWEB)

    Carpenter, S.E.; Doskey, P.V.; Erickson, M.D.; Lindahl, P.C.

    1994-07-01

    This report contains information about technology development for the monitoring and remediation of environmental pollution caused by the release of volatile organic compounds. Topics discussed include: performance specification processes, gas chromatography, mass spectrometer, fiber-optic chemical sensors, infrared spectroscopy, Raman spectroscopy, piezoelectric sensors and electrochemical sensors. These methods are analyzed for their cost efficiency, accuracy, and the ability to meet the needs of the customer.

  1. Intervention of Specific Package of Badminton Drills on Performance Variables in Badminton

    OpenAIRE

    S.Kalaimurugan; R.Mohanakrishnan

    2017-01-01

    The purpose of the study was to analyse the intervention of specific package of badminton drills on performance variables in badminton. For this purpose thirty men Badminton players who attended the state level coaching camp sports authority of Tamilnadu, Chennai were selected as subjects for this study. They were selected all random basis. All the subjects were experienced players who had already participated state level tournaments. The subjects were randomly divided into two equal groups a...

  2. Validation and evaluation of common large-area display set (CLADS) performance specification

    Science.gov (United States)

    Hermann, David J.; Gorenflo, Ronald L.

    1998-09-01

    Battelle is under contract with Warner Robins Air Logistics Center to design a Common Large Area Display Set (CLADS) for use in multiple Command, Control, Communications, Computers, and Intelligence (C4I) applications that currently use 19- inch Cathode Ray Tubes (CRTs). Battelle engineers have built and fully tested pre-production prototypes of the CLADS design for AWACS, and are completing pre-production prototype displays for three other platforms simultaneously. With the CLADS design, any display technology that can be packaged to meet the form, fit, and function requirements defined by the Common Large Area Display Head Assembly (CLADHA) performance specification is a candidate for CLADS applications. This technology independent feature reduced the risk of CLADS development, permits life long technology insertion upgrades without unnecessary redesign, and addresses many of the obsolescence problems associated with COTS technology-based acquisition. Performance and environmental testing were performed on the AWACS CLADS and continues on other platforms as a part of the performance specification validation process. A simulator assessment and flight assessment were successfully completed for the AWACS CLADS, and lessons learned from these assessments are being incorporated into the performance specifications. Draft CLADS specifications were released to potential display integrators and manufacturers for review in 1997, and the final version of the performance specifications are scheduled to be released to display integrators and manufacturers in May, 1998. Initial USAF applications include replacements for the E-3 AWACS color monitor assembly, E-8 Joint STARS graphics display unit, and ABCCC airborne color display. Initial U.S. Navy applications include the E-2C ACIS display. For these applications, reliability and maintainability are key objectives. The common design will reduce the cost of operation and maintenance by an estimated 3.3M per year on E-3 AWACS

  3. Proposal for the modification of the conventional model for establishing performance specifications.

    Science.gov (United States)

    Oosterhuis, Wytze P; Sandberg, Sverre

    2015-05-01

    Appropriate quality of test results is fundamental to the work of the medical laboratory. How to define the level of quality needed is a question that has been subject to much debate. Quality specifications have been defined based on criteria derived from the clinical applicability, validity of reference limits and reference change values, state-of-the-art performance, and other criteria, depending on the clinical application or technical characteristics of the measurement. Quality specifications are often expressed as the total error allowable (TEA) - the total amount of error that is medically, administratively, or legally acceptable. Following the TEA concept, bias and imprecision are combined into one number representing the "maximum allowable" error in the result. The commonly accepted method for calculation of the allowable error based on biological variation might, however, have room for improvement. In the present paper, we discuss common theories on the determination of quality specifications. A model is presented that combines the state-of-the-art with biological variation for the calculation of performance specifications. The validity of reference limits and reference change values are central to this model. The model applies to almost any test if biological variation can be defined. A pragmatic method for the design of internal quality control is presented.

  4. Site-Specific Analyses for Demonstrating Compliance with 10 CFR 61 Performance Objectives - 12179

    Energy Technology Data Exchange (ETDEWEB)

    Grossman, C.J.; Esh, D.W.; Yadav, P.; Carrera, A.G. [U.S. Nuclear Regulatory Commission, 11545 Rockville Pike, Rockville, MD 20852 (United States)

    2012-07-01

    The U.S. Nuclear Regulatory Commission (NRC) is proposing to amend its regulations at 10 CFR Part 61 to require low-level radioactive waste disposal facilities to conduct site-specific analyses to demonstrate compliance with the performance objectives in Subpart C. The amendments would require licensees to conduct site-specific analyses for protection of the public and inadvertent intruders as well as analyses for long-lived waste. The amendments would ensure protection of public health and safety, while providing flexibility to demonstrate compliance with the performance objectives, for current and potential future waste streams. NRC staff intends to submit proposed rule language and associated regulatory basis to the Commission for its approval in early 2012. The NRC staff also intends to develop associated guidance to accompany any proposed amendments. The guidance is intended to supplement existing low-level radioactive waste guidance on issues pertinent to conducting site-specific analyses to demonstrate compliance with the performance objectives. The guidance will facilitate implementation of the proposed amendments by licensees and assist competent regulatory authorities in reviewing the site-specific analyses. Specifically, the guidance provides staff recommendations on general considerations for the site-specific analyses, modeling issues for assessments to demonstrate compliance with the performance objectives including the performance assessment, intruder assessment, stability assessment, and analyses for long-lived waste. This paper describes the technical basis for changes to the rule language and the proposed guidance associated with implementation of the rule language. The NRC staff, per Commission direction, intends to propose amendments to 10 CFR Part 61 to require licensees to conduct site-specific analyses to demonstrate compliance with performance objectives for the protection of public health and the environment. The amendments would require a

  5. The Effect of Relation-Specific Investments in the Supply Chain Triad on Innovation Performance

    Directory of Open Access Journals (Sweden)

    Andrea Gelei

    2016-06-01

    Full Text Available Using a comprehensive survey, this paper analyzes the effect of committed and heavy supply chain relationships characterized by high levels of relation-specific investments in innovation performance in Hungary, an emerging economy in Central and Eastern Europe. For this research, we carry out a two-step analysis. First, we investigate the effect of Relation Specific Investments (RSI on four different innovation-related performance dimensions of a focal firm. In contrast to previous research, we did not limit our analysis to the dyadic relationship level, but rather, we analyzed the triadic supply chain relationships. Uniquely, this paper conceptualizes and measures innovation performance in a complex way, both product and process, but also analyzes incremental and radical innovations. As a second step, the effect of internationalization on the focal firm is tested. Triad level RSI has a positive effect on all innovation related performance dimensions. A test of the moderation effect produced mixed results, indicating the need to treat innovation in a complex, sophisticated way in future research.

  6. Firm-specific factors and financial performance of firms in the Czech Republic

    Directory of Open Access Journals (Sweden)

    Pathirawasam Chandrapala

    2013-01-01

    Full Text Available The objective of this study is to investigate the role of internal factors in generating financial performance of firms in the Czech Republic. The paper examines the impact of firm specific factors on company financial performance of 974 firms in the Czech Republic over the period 2005 to 2008, using data in the Albertina database. Pooled and panel cross-sectional time series techniques are used for the data analysis. Return on Assets (ROA is the dependent variable of the model and eight firm specific factors are introduced as the explanatory variables. Using Return on Assets as the dependent variable, it is established that the firm size, sales growth and capital turnover are having significant positive impact on financial performance of firms. At the same time, debt ratio and inventory reflect significant negative impact on financial performance of firms. Overall explanatory powers of the two models are low and further research is necessary to increase the statistical power of the model. The results from the present study may be very encouraging and useful for managers as well as investors to plan investment and operational activities to achieve profitability objectives more efficiently and effectively. The findings have important managerial implications.

  7. Performance in sports--With specific emphasis on the effect of intensified training.

    Science.gov (United States)

    Bangsbo, J

    2015-12-01

    Performance in most sports is determined by the athlete's technical, tactical, physiological and psychological/social characteristics. In the present article, the physical aspect will be evaluated with a focus on what limits performance, and how training can be conducted to improve performance. Specifically how intensified training, i.e., increasing the amount of aerobic high-intensity and speed endurance training, affects physiological adaptations and performance of trained subjects. Periods of speed endurance training do improve performance in events lasting 30 s-4 min, and when combined with aerobic high-intensity sessions, also performance during longer events. Athletes in team sports involving intense exercise actions and endurance aspects, such as soccer and basketball, can also benefit from intensified training. Speed endurance training does reduce energy expenditure and increase expression of muscle Na(+), K(+) pump α subunits, which may preserve muscle cell excitability and delay fatigue development during intense exercise. When various types of training are conducted in the same period (concurrent training), as done in a number of sports, one type of training may blunt the effect of other types of training. It is not, however, clear how various training modalities are affecting each other, and this issue should be addressed in future studies. © 2015 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  8. Trait compensation and sex-specific aging of performance in male and female professional basketball players.

    Science.gov (United States)

    Lailvaux, Simon P; Wilson, Robbie; Kasumovic, Michael M

    2014-05-01

    Phenotypic traits are often influenced by dynamic resource allocation trade-offs which, when occurring over the course of individual lifespan, may manifest as trait aging. Although aging is studied for a variety of traits that are closely tied to reproduction or reproductive effort, the aging of multiple traits related to fitness in other ways are less well understood. We took advantage of almost 30 years of data on human whole-organism performance in the National Basketball Association (USA) to examine trends of aging in performance traits associated with scoring. Given that patterns of aging differ between sexes in other animal species, we also analyzed a smaller dataset on players in the Women's National Basketball Association to test for potential sex differences in the aging of comparable traits. We tested the hypothesis that age-related changes in a specific aspect of overall performance can be compensated for by elevated expression of another, related aspect. Our analyses suggest that the aging of performance traits used in basketball is generally characterized by senescence in males, whereas age-related changes in basketball performance are less evident in females. Our data also indicate a different rate of senescence of different performance traits associated with scoring over a male's lifetime.

  9. Performance-based quality specifications: the relationship between process critical control parameters, critical quality attributes, and clinical performance.

    Science.gov (United States)

    Short, Steven M; Cogdill, Robert P; Drennen, James K; Anderson, Carl A

    2011-04-01

    The quality of pharmaceutical products is currently evaluated through a series of tests that do not explicitly communicate the clinical consequences of product variability. A previously published risk simulation platform was used to generate quantitative estimates of inefficacy and toxicity for 288 uniform lots of extended-release theophylline tablets displaying various levels of content uniformity and dissolution variability. These data were used to evaluate the univariate specifications utilized in the United States Pharmacopeia (USP) and . Simulation revealed that the specifications are too lenient for content uniformity, both in terms of inefficacy and toxicity, whereas the criteria for dissolution testing are too strict for inefficacy and inaccurate for toxicity. The USP tests also failed to pinpoint the clinical interaction between content uniformity and dissolution variability. Additionally, the simulation platform was used to define the underlying relationship between product quality attributes and clinical performance. Here, content uniformity and Weibull dissolution time constants were used as inputs to the design spaces, which were conditioned on quantitative estimates of inefficacy and toxicity. This methodology enhances the information content of the design space by omitting quality surrogates (e.g., dissolution, moisture content) that are utilized in current design space practices.

  10. Preliminary Derivation of Test Item Clusters for Predicting Injuries, Poor Physical Performance, and Overall Attrition in Basic Combat Training

    Science.gov (United States)

    2006-12-01

    examination and patient self-report measures for cervical radiculopathy. Spine. Jan 1 2003;28(1):52-62. 36 11. Wainner RS, Fritz JM, Irrgang JJ...foot orthosis use and modified activity: a preliminary investigation. Phys Ther. Jan 2004;84(1):49-61. 18. Solomon DH, Avorn J, Warsi A, et al

  11. Reactive Agility Performance in Handball; Development and Evaluation of a Sport-Specific Measurement Protocol.

    Science.gov (United States)

    Spasic, Miodrag; Krolo, Ante; Zenic, Natasa; Delextrat, Anne; Sekulic, Damir

    2015-09-01

    There is no current study that examined sport-specific tests of reactive-agility and change-of-direction-speed (CODS) to replicate real-sport environment in handball (team-handball). This investigation evaluated the reliability and validity of two novel tests designed to assess reactive-agility and CODS of handball players. Participants were female (25.14 ± 3.71 years of age; 1.77 ± 0.09 m and 74.1 ± 6.1 kg) and male handball players (26.9 ± 4.1 years of age; 1.90 ± 0.09 m and 93.90±4.6 kg). Variables included body height, body mass, body mass index, broad jump, 5-m sprint, CODS and reactive-agility tests. Results showed satisfactory reliability for reactive-agility-test and CODS-test (ICC of 0.85-0.93, and CV of 2.4-4.8%). The reactive-agility and CODS shared less than 20% of the common variance. The calculated index of perceptual and reactive capacity (P&RC; ratio between reactive-agility- and CODS-performance) is found to be valid measure in defining true-game reactive-agility performance in handball in both genders. Therefore, the handball athletes' P&RC should be used in the evaluation of real-game reactive-agility performance. Future studies should explore other sport-specific reactive-agility tests and factors associated to such performance in sports involving agile maneuvers. Key pointsReactive agility and change-of-direction-speed should be observed as independent qualities, even when tested over the same course and similar movement templateThe reactive-agility-performance of the handball athletes involved in defensive duties is closer to their non-reactive-agility-score than in their peers who are not involved in defensive dutiesThe handball specific "true-game" reactive-agility-performance should be evaluated as the ratio between reactive-agility and corresponding CODS performance.

  12. 14 CFR Appendix C to Part 91 - Operations in the North Atlantic (NAT) Minimum Navigation Performance Specifications (MNPS) Airspace

    Science.gov (United States)

    2010-01-01

    ...) Minimum Navigation Performance Specifications (MNPS) Airspace C Appendix C to Part 91 Aeronautics and... North Atlantic (NAT) Minimum Navigation Performance Specifications (MNPS) Airspace Section 1 NAT MNPS.... Section 2 The navigation performance capability required for aircraft to be operated in the...

  13. Setting analytical performance specifications based on outcome studies - is it possible?

    Science.gov (United States)

    Horvath, Andrea Rita; Bossuyt, Patrick M M; Sandberg, Sverre; John, Andrew St; Monaghan, Phillip J; Verhagen-Kamerbeek, Wilma D J; Lennartz, Lieselotte; Cobbaert, Christa M; Ebert, Christoph; Lord, Sarah J

    2015-05-01

    The 1st Strategic Conference of the European Federation of Clinical Chemistry and Laboratory Medicine proposed a simplified hierarchy for setting analytical performance specifications (APS). The top two levels of the 1999 Stockholm hierarchy, i.e., evaluation of the effect of analytical performance on clinical outcomes and clinical decisions have been proposed to be replaced by one outcome-based model. This model can be supported by: (1a) direct outcome studies; and (1b) indirect outcome studies investigating the impact of analytical performance of the test on clinical classifications or decisions and thereby on the probability of patient relevant clinical outcomes. This paper reviews the need for outcome-based specifications, the most relevant types of outcomes to be considered, and the challenges and limitations faced when setting outcome-based APS. The methods of Model 1a and b are discussed and examples are provided for how outcome data can be translated to APS using the linked evidence and simulation or decision analytic techniques. Outcome-based APS should primarily reflect the clinical needs of patients; should be tailored to the purpose, role and significance of the test in a well defined clinical pathway; and should be defined at a level that achieves net health benefit for patients at reasonable costs. Whilst it is acknowledged that direct evaluations are difficult and may not be possible for all measurands, all other forms of setting APS should be weighed against that standard, and regarded as approximations. Better definition of the relationship between the analytical performance of tests and health outcomes can be used to set analytical performance criteria that aim to improve the clinical and cost-effectiveness of laboratory tests.

  14. Association of Hematological Variables with Team-Sport Specific Fitness Performance.

    Directory of Open Access Journals (Sweden)

    Franck Brocherie

    Full Text Available We investigated association of hematological variables with specific fitness performance in elite team-sport players.Hemoglobin mass (Hbmass was measured in 25 elite field hockey players using the optimized (2 min CO-rebreathing method. Hemoglobin concentration ([Hb], hematocrit and mean corpuscular hemoglobin concentration (MCHC were analyzed in venous blood. Fitness performance evaluation included a repeated-sprint ability (RSA test (8 x 20 m sprints, 20 s of rest and the Yo-Yo intermittent recovery level 2 (YYIR2.Hbmass was largely correlated (r = 0.62, P0.05. [Hb] and MCHC displayed moderate correlations with both YYIR2TD (r = 0.44 and 0.41; both P0.05.Hbmass is positively correlated with specific aerobic fitness, but not with RSA, in elite team-sport players. Additionally, the negative relationships between YYIR2 and RSA tests performance imply that different hematological mechanisms may be at play. Overall, these results indicate that these two fitness tests should not be used interchangeably as they reflect different hematological mechanisms.

  15. A comparison of systemwide and hospital-specific performance measurement tools.

    Science.gov (United States)

    Yap, Clarence; Siu, Emily; Baker, G Ross; Brown, Adalsteinn D

    2005-01-01

    Balanced scorecards are being implemented at the system and organizational levels to help managers link their organizational strategies with performance data to better manage their healthcare systems. Prior to this study, hospitals in Ontario, Canada, received two editions of the system-level scorecard (SLS)--a framework, based on the original balanced scorecard, that includes four quadrants: system integration and management innovation (learning and growth), clinical utilization and outcomes (internal processes), patient satisfaction (customer), and financial performance and condition (financial). This study examines the uptake of the SLS framework and indicators into institution-specific scorecards for 22 acute care institutions and 2 non-acute-care institutions. This study found that larger (teaching and community) hospitals were significantly more likely to use the SLS framework to report performance data than did small hospitals (p scorecards. However, all hospitals in the study incorporated indicators that required data collection and analysis beyond the SLS framework. The study findings suggest that SLS may assist hospitals in developing institution-specific scorecards for hospital management and that the balanced scorecard model can be modified to meet the needs of a variety of hospitals. Based on the insight from this study and other activities that explore top priorities for hospital management, the issues related to efficiency and human resources should be further examined using SLSs.

  16. Preliminary performance assessment for the Waste Isolation Pilot Plant, December 1992. Volume 1, Third comparison with 40 CFR 191, Subpart B

    Energy Technology Data Exchange (ETDEWEB)

    1992-12-01

    Before disposing of transuranic radioactive wastes in the Waste Isolation Pilot Plant (WIPP), the United States Department of Energy (DOE) must evaluate compliance with applicable long-term regulations of the United States Environmental Protection Agency (EPA). Sandia National Laboratories is conducting iterative performance assessments of the WIPP for the DOE to provide interim guidance while preparing for final compliance evaluations. This volume contains an overview of WIPP performance assessment and a preliminary comparison with the long-term requirements of the Environmental Radiation Protection Standards for Management and Disposal of Spent Nuclear Fuel, High-Level and Transuranic Radioactive Wastes (40 CFR 191, Subpart B).

  17. Input- and Output-Specific Regulation of Serial Order Performance by Corticostriatal Circuits.

    Science.gov (United States)

    Rothwell, Patrick E; Hayton, Scott J; Sun, Gordon L; Fuccillo, Marc V; Lim, Byung Kook; Malenka, Robert C

    2015-10-21

    The serial ordering of individual movements into sequential patterns is thought to require synaptic plasticity within corticostriatal circuits that route information through the basal ganglia. We used genetically and anatomically targeted manipulations of specific circuit elements in mice to isolate the source and target of a corticostriatal synapse that regulates the performance of a serial order task. This excitatory synapse originates in secondary motor cortex, terminates on direct pathway medium spiny neurons in the dorsolateral striatum, and is strengthened by serial order learning. This experience-dependent and synapse-specific form of plasticity may sculpt the balance of activity in basal ganglia circuits during sequential movements, driving a disparity in striatal output that favors the direct pathway. This disparity is necessary for execution of responses in serial order, even though both direct and indirect pathways are active during movement initiation, suggesting dynamic modulation of corticostriatal circuitry contributes to the choreography of behavioral routines.

  18. Performance and interaction anxiety: specific relationships with other- and self-evaluation concerns.

    Science.gov (United States)

    Hook, Julie N; Valentiner, David P; Connelly, Jill

    2013-03-01

    This study examines whether performance anxiety (PA) is specifically associated with other-evaluation concerns and interaction anxiety (IA) with self-evaluation concerns. Individuals with public speaking fears and high levels of PA or IA were distinguishable from nonanxious controls on measures taken during a public speaking challenge. In addition, high PA individuals exhibited more observer-rated negative speech characteristics in an Other-Evaluation condition compared to a Self-Evaluation condition, but high IA individuals and nonanxious individuals did not. These results provide some evidence for the distinctiveness of these dimensions of social anxiety.

  19. Design of PID Controllers of Anti-aircraft Artillery Servo System with Multiple Performance Specifications

    Institute of Scientific and Technical Information of China (English)

    LI Yin-ya; SHENG An-dong; WANG Yuan-gang

    2007-01-01

    A novel design method for determining the proportional-integral-derivative(PID) controller gains of an anti-aircraft artillery servo system with multiple performance specifications based on a particle swarm optimization (PSO) algorithm is proposed. First, a performance criterion evolution function combined with the system maximum displacement settling time, rise time, overshoot, steady state error, constant velocity tracking error and sine wave tracking error is defined. Second, the optimization problem of PID controller parameters and the searching procedure of PSO algorithm are constructed. Finally, the optimal or near optimal PID controller parameters are fast and easily obtained by solving the above optimization problem on the given controller parameter space following the PSO searching procedure. The simulation results show the effectiveness of the proposed controllers.

  20. Dietary nitrate supplementation improves team sport-specific intense intermittent exercise performance.

    Science.gov (United States)

    Wylie, Lee J; Mohr, Magni; Krustrup, Peter; Jackman, Sarah R; Ermιdis, Georgios; Kelly, James; Black, Matthew I; Bailey, Stephen J; Vanhatalo, Anni; Jones, Andrew M

    2013-07-01

    Recent studies have suggested that dietary inorganic nitrate (NO₃(-)) supplementation may improve muscle efficiency and endurance exercise tolerance but possible effects during team sport-specific intense intermittent exercise have not been examined. We hypothesized that NO₃(-) supplementation would enhance high-intensity intermittent exercise performance. Fourteen male recreational team-sport players were assigned in a double-blind, randomized, crossover design to consume 490 mL of concentrated, nitrate-rich beetroot juice (BR) and nitrate-depleted placebo juice (PL) over ~30 h preceding the completion of a Yo-Yo intermittent recovery level 1 test (Yo-Yo IR1). Resting plasma nitrite concentration ([NO₂(-)]) was ~400% greater in BR compared to PL. Plasma [NO₂(-)] declined by 20% in PL (P exercise to end-exercise. Performance in the Yo-Yo IR1 was 4.2% greater (P exercise and may be a useful ergogenic aid for team sports players.

  1. Performance and specificity of the covalently linked immunomagnetic separation-ATP method for rapid detection and enumeration of enterococci in coastal environments.

    Science.gov (United States)

    Zimmer-Faust, Amity G; Thulsiraj, Vanessa; Ferguson, Donna; Jay, Jennifer A

    2014-05-01

    The performance and specificity of the covalently linked immunomagnetic separation-ATP (Cov-IMS/ATP) method for the detection and enumeration of enterococci was evaluated in recreational waters. Cov-IMS/ATP performance was compared with standard methods: defined substrate technology (Enterolert; IDEXX Laboratories), membrane filtration (EPA Method 1600), and an Enterococcus-specific quantitative PCR (qPCR) assay (EPA Method A). We extend previous studies by (i) analyzing the stability of the relationship between the Cov-IMS/ATP method and culture-based methods at different field sites, (ii) evaluating specificity of the assay for seven ATCC Enterococcus species, (iii) identifying cross-reacting organisms binding the antibody-bead complexes with 16S rRNA gene sequencing and evaluating specificity of the assay to five nonenterococcus species, and (iv) conducting preliminary tests of preabsorption as a means of improving the assay. Cov-IMS/ATP was found to perform consistently and with strong agreement rates (based on exceedance/compliance with regulatory limits) of between 83% and 100% compared to the culture-based Enterolert method at a variety of sites with complex inputs. The Cov-IMS/ATP method is specific to five of seven different Enterococcus spp. tested. However, there is potential for nontarget bacteria to bind the antibody, which may be reduced by purification of the IgG serum with preabsorption at problematic sites. The findings of this study help to validate the Cov-IMS/ATP method, suggesting a predictable relationship between the Cov-IMS/ATP method and traditional culture-based methods, which will allow for more widespread application of this rapid and field-portable method for coastal water quality assessment.

  2. The Technical Specification and Physical Performance Level of Line Pipes for West-East Gas Pipeline

    Institute of Scientific and Technical Information of China (English)

    FengBin; WangMaotang; LiuFangming; XiaoLiming

    2004-01-01

    The west-east gas transmission engineering is an important project attracting domestic and foreign attention. The gas pipeline used in this project is a gas pipeline with the longest distance, largest pipe diameter and highest transmission pressure in the history of petroleum pipeline construction of China. For the construction of top-rank gas pipeline in the world with high standard, high speed and high benefit, the key of specifying production of metallurgical and pipe-making enterprises and ensuring quality performance of the steel and steel pipe is to research and formulate a feasible and satisfactory technical Specification for engineering steel and steel pipe with international level. In this paper the author introduces the establishment of the technical specification for West-East gas pipeline project, and lays emphasis on the analysis and discussion of principle and method determining major technical indexes related to line pipes for West-East gas pipeline. The author also introduces actual material selection of gas pipeline home and abroad, and presents examination and application of the technical specification for West-East gas pipeline.

  3. Proximity-activated nanoparticles: in vitro performance of specific structural modification by enzymatic cleavage

    Directory of Open Access Journals (Sweden)

    R Adam Smith

    2008-03-01

    Full Text Available R Adam Smith, Sarah L Sewell, Todd D GiorgioDepartment of Biomedical Engineering, Vanderbilt University, Nashville, TN, USAAbstract: The development and in vitro performance of a modular nanoscale system capable of specific structural modification by enzymatic activity is described in this work. Due to its small physical size and adaptable characteristics, this system has the potential for utilization in targeted delivery systems and biosensing. Nanoparticle probes were synthesized containing two distinct fluorescent species including a quantum dot base particle and fluorescently labeled cleavable peptide substrate. Activity of these probes was monitored by gel electrophoresis with quantitative cleavage measurements made by fluorometric analysis. The model proximity-activated nanoparticles studied here exhibit significant susceptibility to cleavage by matrix metalloprotease-7 (MMP-7 at physiologically relevant concentrations, with nearly complete cleavage of available substrate molecules after 24 hours. This response is specific to MMP-7 enzyme activity, as cleavage is completely inhibited with the addition of EDTA. Utilization of enzyme-specific modification is a sensitive approach with broad applications for targeted therapeutics and biosensing. The versatility of this nanoparticle system is highlighted in its modular design, as it has the capability to integrate characteristics for detection, biosensing, targeting, and payload delivery into a single, multifunctional nanoparticle structure.Keywords: quantum dot, MMP-7, protease, proximity activated nanoparticle

  4. Sequence specific motor performance gains after memory consolidation in children and adolescents.

    Directory of Open Access Journals (Sweden)

    Shoshi Dorfberger

    Full Text Available Memory consolidation for a trained sequence of finger opposition movements, in 9- and 12-year-old children, was recently found to be significantly less susceptible to interference by a subsequent training experience, compared to that of 17-year-olds. It was suggested that, in children, the experience of training on any sequence of finger movements may affect the performance of the sequence elements, component movements, rather than the sequence as a unit; the latter has been implicated in the learning of the task by adults. This hypothesis implied a possible childhood advantage in the ability to transfer the gains from a trained to the reversed, untrained, sequence of movements. Here we report the results of transfer tests undertaken to test this proposal in 9-, 12-, and 17-year-olds after training in the finger-to-thumb opposition sequence (FOS learning task. Our results show that the performance gains in the trained sequence partially transferred from the left, trained hand, to the untrained hand at 48-hours after a single training session in the three age-groups tested. However, there was very little transfer of the gains from the trained to the untrained, reversed, sequence performed by either hand. The results indicate sequence specific post-training gains in FOS performance, as opposed to a general improvement in performance of the individual, component, movements that comprised both the trained and untrained sequences. These results do not support the proposal that the reduced susceptibility to interference, in children before adolescence, reflects a difference in movement syntax representation after training.

  5. Are acute effects of maximal dynamic contractions on upper-body ballistic performance load specific?

    Science.gov (United States)

    Markovic, Goran; Simek, Sanja; Bradic, Asim

    2008-11-01

    This study investigated the acute effects of upper-body maximal dynamic contractions on maximal throwing speed with 0.55- and 4-kg medicine balls. It was hypothesized that heavy preloading would transiently improve throwing performance only when overcoming the heavier of the two loads. Twenty-three male volunteers were randomly allocated into experimental (n = 11) and control (n = 12) groups. Both groups performed initial and final seated medicine ball throws from the chest, and the maximal medicine ball speed was measured by means of a radar gun. Between the two measurements, the control group rested passively for 15 minutes, and the experimental group performed three sets of three-repetition maximum bench presses. For the 0.55-kg load, a 2 x 2 repeated-measures analysis of variance revealed no significant effect of time x group interaction (p = 0.22), as well as no significant time (p = 0.22) or group (p = 0.72) effects. In contrast, for the 4-kg load, a significant time x group interaction (p = 0.004) and a significant time (p = 0.035) but not group (p = 0.77) effect were observed. Analysis of simple main effects revealed that the experimental group significantly (8.3%; p ballistic performance might be load specific. In a practical sense, our findings suggest that the use of upper-body heavy resistance exercise before ballistic throwing movements against moderate external loads might be an efficient training strategy for improving an athlete's upper-body explosive performance.

  6. Optimization on the impeller of a low-specific-speed centrifugal pump for hydraulic performance improvement

    Science.gov (United States)

    Pei, Ji; Wang, Wenjie; Yuan, Shouqi; Zhang, Jinfeng

    2016-09-01

    In order to widen the high-efficiency operating range of a low-specific-speed centrifugal pump, an optimization process for considering efficiencies under 1.0 Q d and 1.4 Q d is proposed. Three parameters, namely, the blade outlet width b 2, blade outlet angle β 2, and blade wrap angle φ, are selected as design variables. Impellers are generated using the optimal Latin hypercube sampling method. The pump efficiencies are calculated using the software CFX 14.5 at two operating points selected as objectives. Surrogate models are also constructed to analyze the relationship between the objectives and the design variables. Finally, the particle swarm optimization algorithm is applied to calculate the surrogate model to determine the best combination of the impeller parameters. The results show that the performance curve predicted by numerical simulation has a good agreement with the experimental results. Compared with the efficiencies of the original impeller, the hydraulic efficiencies of the optimized impeller are increased by 4.18% and 0.62% under 1.0 Q d and 1.4Qd, respectively. The comparison of inner flow between the original pump and optimized one illustrates the improvement of performance. The optimization process can provide a useful reference on performance improvement of other pumps, even on reduction of pressure fluctuations.

  7. Preliminary design package for prototype solar heating system

    Science.gov (United States)

    1978-01-01

    A summary is given of the preliminary analysis and design activity on solar heating systems. The analysis was made without site specific data other than weather; therefore, the results indicate performance expected under these special conditions. Major items include system candidates, design approaches, trade studies and other special data required to evaluate the preliminary analysis and design. The program calls for the development and delivery of eight prototype solar heating and cooling systems for installation and operational test.

  8. Site-specific seismic probabilistic tsunami hazard analysis: performances and potential applications

    Science.gov (United States)

    Tonini, Roberto; Volpe, Manuela; Lorito, Stefano; Selva, Jacopo; Orefice, Simone; Graziani, Laura; Brizuela, Beatriz; Smedile, Alessandra; Romano, Fabrizio; De Martini, Paolo Marco; Maramai, Alessandra; Piatanesi, Alessio; Pantosti, Daniela

    2017-04-01

    Seismic Probabilistic Tsunami Hazard Analysis (SPTHA) provides probabilities to exceed different thresholds of tsunami hazard intensity, at a specific site or region and in a given time span, for tsunamis caused by seismic sources. Results obtained by SPTHA (i.e., probabilistic hazard curves and inundation maps) represent a very important input to risk analyses and land use planning. However, the large variability of source parameters implies the definition of a huge number of potential tsunami scenarios, whose omission could lead to a biased analysis. Moreover, tsunami propagation from source to target requires the use of very expensive numerical simulations. At regional scale, the computational cost can be reduced using assumptions on the tsunami modeling (i.e., neglecting non-linear effects, using coarse topo-bathymetric meshes, empirically extrapolating maximum wave heights on the coast). On the other hand, moving to local scale, a much higher resolution is required and such assumptions drop out, since detailed inundation maps require significantly greater computational resources. In this work we apply a multi-step method to perform a site-specific SPTHA which can be summarized in the following steps: i) to perform a regional hazard assessment to account for both the aleatory and epistemic uncertainties of the seismic source, by combining the use of an event tree and an ensemble modeling technique; ii) to apply a filtering procedure which use a cluster analysis to define a significantly reduced number of representative scenarios contributing to the hazard of a specific target site; iii) to perform high resolution numerical simulations only for these representative scenarios and for a subset of near field sources placed in very shallow waters and/or whose coseismic displacements induce ground uplift or subsidence at the target. The method is applied to three target areas in the Mediterranean located around the cities of Milazzo (Italy), Thessaloniki (Greece) and

  9. 48 CFR 52.246-19 - Warranty of Systems and Equipment under Performance Specifications or Design Criteria.

    Science.gov (United States)

    2010-10-01

    ... Equipment under Performance Specifications or Design Criteria. 52.246-19 Section 52.246-19 Federal... under Performance Specifications or Design Criteria. As prescribed in 46.710(c)(1), the contracting officer may insert a clause substantially as follows: Warranty of Systems and Equipment Under...

  10. 40 CFR Table F-1 to Subpart F of... - Performance Specifications for PM2.5 Class II Equivalent Samplers

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 5 2010-07-01 2010-07-01 false Performance Specifications for PM2.5 Class II Equivalent Samplers F Table F-1 to Subpart F of Part 53 Protection of Environment ENVIRONMENTAL..., Subpt. F, Table F-1 Table F-1 to Subpart F of Part 53—Performance Specifications for PM2.5 Class...

  11. The reliability and validity of a soccer-specific nonmotorised treadmill simulation (intermittent soccer performance test).

    Science.gov (United States)

    Aldous, Jeffrey W F; Akubat, Ibrahim; Chrismas, Bryna C R; Watkins, Samuel L; Mauger, Alexis R; Midgley, Adrian W; Abt, Grant; Taylor, Lee

    2014-07-01

    This study investigated the reliability and validity of a novel nonmotorised treadmill (NMT)-based soccer simulation using a novel activity category called a "variable run" to quantify fatigue during high-speed running. Twelve male University soccer players completed 3 familiarization sessions and 1 peak speed assessment before completing the intermittent soccer performance test (iSPT) twice. The 2 iSPTs were separated by 6-10 days. The total distance, sprint distance, and high-speed running distance (HSD) were 8,968 ± 430 m, 980 ± 75 m and 2,122 ± 140 m, respectively. No significant difference (p > 0.05) was found between repeated trials of the iSPT for all physiological and performance variables. Reliability measures between iSPT1 and iSPT2 showed good agreement (coefficient of variation: 0.80). Furthermore, the variable run phase showed HSD significantly decreased (p ≤ 0.05) in the last 15 minutes (89 ± 6 m) compared with the first 15 minutes (85 ± 7 m), quantifying decrements in high-speed exercise compared with the previous literature. This study validates the iSPT as a NMT-based soccer simulation compared with the previous match-play data and is a reliable tool for assessing and monitoring physiological and performance variables in soccer players. The iSPT could be used in a number of ways including player rehabilitation, understanding the efficacy of nutritional interventions, and also the quantification of environmentally mediated decrements on soccer-specific performance.

  12. The Effects of Goal Specificity and Scaffolding on Programming Performance and Self-Regulation in Game Design

    Science.gov (United States)

    Feng, Chia-Yen; Chen, Ming-Puu

    2014-01-01

    The purpose of this study was to investigate the influence of goal specificity and scaffolding on the programming performance and self-regulation of elementary students engaged in learning game design. This study recruited 232 students for the experimental activities. Two levels of goal specificity were employed: specific and nonspecific.…

  13. The Impact of 2008 Global Financial Crisis on the Performance of Selected Indonesian Stocks: A Preliminary Study

    Directory of Open Access Journals (Sweden)

    Edwin Suparman

    2014-08-01

    Full Text Available This research is a preliminary study that analyzes the impact of the US financial markets on Indonesian financial markets during the 2008 global financial crisis. It specifically investigates the occurrence of contagion effect in the Indonesian IHSG index and selected LQ45 stocks with the US S&P500 index by the measurement of correlation using simple correlation, EWMA, OGARCH, and DCC GARCH. It also attempts to discuss on the decoupling of Indonesian market and provide recommendations on dealing with future similar events.

  14. Investigating the Effect of Implicit Browsing Behaviour on Students’ Performance in a Task Specific Context

    Directory of Open Access Journals (Sweden)

    Stephen Akuma

    2014-04-01

    Full Text Available This paper focuses on how students access web pages in a task specific information retrieval. An investigation on how students search the web for their current needs was carried out and students’ behavioural characteristics as they surf the internet to answer some given online multiple choice questions was collected. Twenty three students participated in the study and a number of behavioural characteristics were captured. Camtasia studio 7 was used to record their searching activity. The result shows that 328 web pages were visited by the students, and among the parameters captured, the time spent on the search task has a stronger correlation with the students’ performance than any other captured parameter. The time spent on a document can be used as a good implicit indicator to infer learner’s interest in a context based recommender system.

  15. Effect of surface-specific training on 20-m sprint performance on sand and grass surfaces.

    Science.gov (United States)

    Binnie, Martyn J; Peeling, Peter; Pinnington, Hugh; Landers, Grant; Dawson, Brian

    2013-12-01

    This study compared the effect of an 8-week preseason conditioning program conducted on a sand (SAND) or grass (GRASS) surface on 20-m sprint performance. Twelve team-sport athletes were required to attend three 1-hour training sessions per week, including 2 surface-specific sessions (SAND, n = 6 or GRASS, n = 6) and 1 group session (conducted on grass). Throughout the training period, 20-m sprint times of all athletes were recorded on both sand and grass surfaces at the end of weeks 1, 4, and 8. Results showed a significant improvement in 20-m sand time in the SAND group only (p grass time improved equally in both training subgroups (p grass speed gains when incorporating sand surfaces into a preseason program.

  16. Specifics of Pulsed Arc Welding Power Supply Performance Based On A Transistor Switch

    Science.gov (United States)

    Krampit, N. Yu; Kust, T. S.; Krampit, M. A.

    2016-08-01

    Specifics of designing a pulsed arc welding power supply device are presented in the paper. Electronic components for managing large current was analyzed. Strengths and shortcomings of power supply circuits based on thyristor, bipolar transistor and MOSFET are outlined. As a base unit for pulsed arc welding was chosen MOSFET transistor, which is easy to manage. Measures to protect a transistor are given. As for the transistor control device is a microcontroller Arduino which has a low cost and adequate performance of the work. Bead transfer principle is to change the voltage on the arc in the formation of beads on the wire end. Microcontroller controls transistor when the arc voltage reaches the threshold voltage. Thus there is a separation and transfer of beads without splashing. Control strategies tested on a real device and presented. The error in the operation of the device is less than 25 us, it can be used controlling drop transfer at high frequencies (up to 1300 Hz).

  17. Preliminary parametric performance assessment of potential final waste forms for alpha low-level waste at the Idaho National Engineering Laboratory. Revision 1

    Energy Technology Data Exchange (ETDEWEB)

    Smith, T.H.; Sussman, M.E. [Lockheed Idaho Technologies Co., Idaho Falls, ID (United States); Myers, J.; Djordjevic, S.M.; DeBiase, T.A.; Goodrich, M.T.; DeWitt, D. [IT Corp., Albuquerque, NM (United States)

    1995-08-01

    This report presents a preliminary parametric performance assessment (PA) of potential waste disposal systems for alpha-contaminated, mixed, low-level waste (ALLW) currently stored at the Transuranic Storage Area of INEL. The ALLW, which contains from 10 to 100 nCi/g of transuranic (TRU) radionuclides, is awaiting treatment and disposal. The purpose of this study was to examine the effects of several parameters on the radiological-confinement performance of potential disposal systems for the ALLW. The principal emphasis was on the performance of final waste forms (FWFs). Three categories of FWF (cement, glass, and ceramic) were addressed by evaluating the performance of two limiting FWFs for each category. Performance at five conceptual disposal sites was evaluated to illustrate the effects of site characteristics on the performance of the total disposal system. Other parameters investigated for effects on receptor dose included inventory assumptions, TRU radionuclide concentration, FWF fracture, disposal depth, water infiltration rates, subsurface-transport modeling assumptions, receptor well location, intrusion scenario assumptions, and the absence of waste immobilization. These and other factors were varied singly and in some combinations. The results indicate that compliance of the treated and disposed ALLW with the performance objectives depends on the assumptions made, as well as on the FWF and the disposal site. Some combinations result in compliance, while others do not. The implications of these results for decision making relative to treatment and disposal of the INEL ALLW are discussed. The report compares the degree of conservatism in this preliminary parametric PA against that in four other PAs and one risk assessment. All of the assessments addressed the same disposal site, but different wastes. The report also presents a qualitative evaluation of the uncertainties in the PA and makes recommendations for further study.

  18. The emotional eyewitness: the effects of emotion on specific aspects of eyewitness recall and recognition performance.

    Science.gov (United States)

    Houston, Kate A; Clifford, Brian R; Phillips, Louise H; Memon, Amina

    2013-02-01

    The present set of experiments aimed to investigate the effects of negative emotion on specific aspects of eyewitness recall and recognition performance. The experience of emotion was manipulated between subjects, with participants either viewing a crime scenario (a mugging) or a neutral scenario (a conversation). Eyewitness recall was categorized into descriptions of the perpetrator, critical incident, victim, and environmental details. The completeness and accuracy of eyewitness recall across categories of detail were measured in Experiment 1. A significant main effect of negative emotion was found for the completeness of recall. Furthermore, a significant main effect of the completeness of eyewitness statements was found, but not for their accuracy. However, these main effects were qualified by a significant interaction between emotion and category of detail recalled. Specifically, emotional participants provided a more complete description of the perpetrator than neutral participants; however, they were less able than their neutral counterparts to describe what the perpetrator did to the victim. In light of these findings, Experiment 2 investigated whether enhanced completeness of perpetrator descriptions during recall translated into an enhanced ability to recognize the perpetrator from a photographic lineup by emotional compared with neutral participants. Results from Experiment 2 suggest that while emotional participants again provide a more complete description of the perpetrator, they are less able than their neutral counterparts to recognize the perpetrator from a photographic lineup. Results are discussed in terms of a retrieval motivation hypothesis of negative emotional experience and the possible consequences for eyewitness testimony.

  19. Investigating Commercial Cellulase Performances Toward Specific Biomass Recalcitrance Factors Using Reference Substrates

    Energy Technology Data Exchange (ETDEWEB)

    Ju, Xiaohui; Bowden, Mark E.; Engelhard, Mark H.; Zhang, Xiao

    2014-04-01

    Three commercial cellulase preparations, Novozymes Cellic® Ctec2, Dupont Accellerase® 1500, and DSM Cytolase CL, were evaluated for their hydrolytic activity using a set of reference biomass substrates with controlled substrate characteristics. It was found that lignin remains a significant recalcitrance factor to all the preparations, although different enzyme preparations respond to the inhibitory effect of lignin differently. Also, different types of biomass lignin can inhibit cellulose enzymes in different manners. Enhancing enzyme activity toward biomass fiber swelling is an area significantly contributing to potential improvement in cellulose performance. While the degree of polymerization of cellulose in the reference substrates did not present a major recalcitrance factor to Novozymes Cellic® Ctec2, cellulose crystallite has been shown to have a significant lower reactivity toward all enzyme mixtures. The presence of polysaccharide monooxygenases (PMOs) in Novozymes Ctec2 appears to enhance enzyme activity toward decrystallization of cellulose. This study demonstrated that reference substrates with controlled chemical and physical characteristics of structural features can be applied as an effective and practical strategy to identify cellulosic enzyme activities toward specific biomass recalcitrance factor(s) and provide specific targets for enzyme improvement.

  20. The ArT\\'eMiS wide-field submillimeter camera: preliminary on-sky performances at 350 microns

    CERN Document Server

    Reveret, Vincent; Pennec, Jean Le; Talvard, Michel; Agnèse, Patrick; Arnaud, Agnès; Clerc, Laurent; de Breuck, Carlos; Cigna, Jean-Charles; Delisle, Cyrille; Doumayrou, Eric; Duband, Lionel; Dubreuil, Didier; Dumaye, Luc; Ercolani, Eric; Gallais, Pascal; Groult, Elodie; Jourdan, Thierry; Leriche, Bernadette; Maffei, Bruno; Lortholary, Michel; Martignac, Jérôme; Rabaud, Wilfried; Relland, Johan; Rodriguez, Louis; Vandeneynde, Aurélie; Visticot, François

    2014-01-01

    ArTeMiS is a wide-field submillimeter camera operating at three wavelengths simultaneously (200, 350 and 450 microns). A preliminary version of the instrument equipped with the 350 microns focal plane, has been successfully installed and tested on APEX telescope in Chile during the 2013 and 2014 austral winters. This instrument is developed by CEA (Saclay and Grenoble, France), IAS (France) and University of Manchester (UK) in collaboration with ESO. We introduce the mechanical and optical design, as well as the cryogenics and electronics of the ArTeMiS camera. ArTeMiS detectors are similar to the ones developed for the Herschel PACS photometer but they are adapted to the high optical load encountered at APEX site. Ultimately, ArTeMiS will contain 4 sub-arrays at 200 microns and 2x8 sub-arrays at 350 and 450 microns. We show preliminary lab measurements like the responsivity of the instrument to hot and cold loads illumination and NEP calculation. Details on the on-sky commissioning runs made in 2013 and 2014...

  1. The Effect of Viscosity on Performance of a Low Specific Speed Centrifugal Pump

    Directory of Open Access Journals (Sweden)

    Rouhollah Torabi

    2016-01-01

    Full Text Available Centrifugal pump delivery head and flow rate drop effectively during the pumping of viscous fluids. Several methods and correlations have been developed to predict reduction rate in centrifugal pump performance when handling viscous fluids, but their results are not in very good agreement with each other. In this study, a common industrial low specific speed pump, which is extensively used in different applications, is studied. The entire pump, including impeller, volute, pipes, front and rear sidewall gaps, and balance holes, is simulated in Computational Fluid Dynamics and 3D full Navier Stokes equations are solved. CFD results are compared with experimental data such as pump performance curves, static pressure in casing, and disk friction loss. Dimensionless angular velocity and leakage rate are investigated in sidewall gap and efficiency variation due to viscosity is studied. The results demonstrate that the behavior of the fluid in sidewall gap is strictly sensitive to viscosity. Increasing viscosity improves the volumetric efficiency by reducing internal leakage through wear rings and balance holes, causing, however, a significant fall in the disk and overall efficiency. Results lead to some recommendations for designing centrifugal pumps which may be used in transferring viscous fluids.

  2. Diagnostic performance and therapeutic consequence of thromboelastometry activated by kaolin versus a panel of specific reagents.

    Science.gov (United States)

    Larsen, Ole Halfdan; Fenger-Eriksen, Christian; Christiansen, Kirsten; Ingerslev, Jørgen; Sørensen, Benny

    2011-08-01

    Thromboelastography/metry (TEG®; Haemoscope, Niles, IL/ROTEM®; Tem International GmbH, Munich, Germany) is increasingly used to guide transfusion therapy. This study investigated the diagnostic performance and therapeutic consequence of using kaolin-activated whole blood compared with a panel of specific TEM®-reagents to distinguish: dilutional coagulopathy, thrombocytopenia, hyperfibrinolysis, and heparinization. Blood was drawn from 11 healthy volunteers. Dilutional coagulopathy was generated by 50% dilution with hydroxyethyl starch 130/0.4 whereas thrombocytopenia (mean platelet count 20 ×10⁹/l) was induced using a validated model. Hyperfibrinolysis and heparin contamination were generated by tissue plasminogen activator 2 nM and unfractionated heparin 0.1U/ml, respectively. Coagulation tests were run on ROTEM® delta. Kaolin-activated whole blood showed no differences between dilutional coagulopathy and thrombocytopenia (mean clotting time 450 s vs. 516 s, α-angle 47.1° vs. 41.5°, maximum clot firmness 35.0 mm vs. 34.2 mm, all P values ≥0.14). Hyperfibrinolysis specifically disclosed an increased maximum lysis (median: 100%, all P values less than 0.001), and heparin induced a distinctly prolonged clotting time (2283 s, all P values less than 0.02). The coagulopathies were readily distinguishable using a panel of TEM-reagents. In particular, dilutional coagulopathy was separated from thrombocytopenia using FIBTEM (maximum clot firmness 1.9 mm vs. 11.2 mm, P kaolin suggested platelets in case of dilutional coagulopathy, whereas an algorithm applying TEM-reagents suggested fibrinogen. Monoanalysis with kaolin was unable to distinguish coagulopathies caused by dilution from that of thrombocytopenia. Algorithms based on the use of kaolin may lead to unnecessary transfusion with platelets, whereas the application of TEM-reagents may result in goal-directed fibrinogen substitution.

  3. Determination of ANA specificity using multiplexed fluorescent microsphere immunoassay in patients with ANA positivity at high titres after infliximab treatment: preliminary results.

    Science.gov (United States)

    Caramaschi, Paola; Ruzzenente, Orazio; Pieropan, Sara; Volpe, Alessandro; Carletto, Antonio; Bambara, Lisa Maria; Biasi, Domenico

    2007-05-01

    To evaluate ANA specificity using the fully automated multiplexed fluorescent microsphere immunoassay in patients affected either by rheumatoid arthritis or ankylosing spondylitis who developed strong positivity for ANA as assessed by indirect immunofluorescent method on HEp-2 cells during infliximab treatment. Three men affected by ankylosing spondylitis and 12 women affected by rheumatoid arthritis who developed ANA positivity at high titres during infliximab treatment underwent the identification of ANA specificity by multiplexed fluorescent microsphere immunoassay; moreover anti-DNA and anti-ENA antibodies were tested by indirect immunofluorescence and ELISA method, respectively. In 4 out of 15 cases, the determination of ANA reactivity by multiplexed fluorescent microsphere immunoassay was also performed on the serum collected before infliximab administration. One patient affected by rheumatoid arthritis showed multiple ANA reactivities against SS-A, SS-B, RNP, Sm, Jo-1 and histones; one patient affected by ankylosing spondylitis resulted positive for the same autoantibodies, except for anti-Sm antibody. Moreover, two patients, one with rheumatoid arthritis and one with ankylosing spondylitis, showed single antibody specificity to SS-B and RNP, respectively. The remaining 11 cases did not show any positivity. Instead, all the patients resulted negative for anti-ENA antibodies by the ELISA method. In the four cases tested for ANA specificity by multiplexed fluorescent microsphere immunoassay before and after infliximab administration no difference was found. The search for anti-DNA antibody always resulted negative by both the traditional immunofluorescent assay and the novel technique. The use of multiplexed fluorescent microsphere immunoassay in patients treated with infliximab with ANA positivity at high titres allowed to find some ANA specificities which were not revealed by ELISA method. Nevertheless, the majority of patients resulted negative in spite of

  4. Physical injury assessment of male versus female chiropractic students when learning and performing various adjustive techniques: a preliminary investigative study

    Directory of Open Access Journals (Sweden)

    Huber Laura L

    2006-08-01

    Full Text Available Abstract Background Reports of musculoskeletal injuries that some chiropractic students experienced while in the role of adjustor became increasingly evident and developed into the basis of this study. The main objective of this study was to survey a select student population and identify, by gender, the specific types of musculoskeletal injuries they experienced when learning adjustive techniques in the classroom, and performing them in the clinical setting. Methods A survey was developed to record musculoskeletal injuries that students reported to have sustained while practicing chiropractic adjustment set-ups and while delivering adjustments. The survey was modeled from similar instruments used in the university's clinic as well as those used in professional practice. Stratified sampling was used to obtain participants for the study. Data reported the anatomical areas of injury, adjustive technique utilized, the type of injury received, and the recovery time from sustained injuries. The survey also inquired as to the type and area of any past physical injuries as well as the mechanism(s of injury. Results Data obtained from the study identified injuries of the shoulder, wrist, elbow, neck, low back, and mid-back. The low back was the most common injury site reported by females, and the neck was the most common site reported by males. The reported wrist injuries in both genders were 1% male complaints and 17% female complaints. A total of 13% of female respondents reported shoulder injuries, whereas less than 1% of male respondents indicated similar complaints. Conclusion The data collected from the project indicated that obtaining further information on the subject would be worthwhile, and could provide an integral step toward developing methods of behavior modification in an attempt to reduce and/or prevent the incidence of musculoskeletal injuries.

  5. Determination of plasma lactic acid concentration and specific activity using high-performance liquid chromatography.

    Science.gov (United States)

    Bleiberg, B; Steinberg, J J; Katz, S D; Wexler, J; LeJemtel, T

    1991-08-23

    Assessment of lactate metabolism is of particular interest during exercise and in disease states such as diabetes, shock, and absorptive abnormalities of short-chain fatty acids by the colon. We describe an analytical method that introduces radio-active tracers and high-performance liquid chromatography (HPLC) to simultaneously analyze concentrations and specific activities (SAs) of plasma lactate. The HPLC conditions included separation on a reversed-phase column (octadecylsilane) and an isocratic buffer (30% acetonitrile in water). [3H]Acetate served as an internal standard. Lactate and acetate were extracted from plasma samples with diethyl ether following a pH adjustment to less than 1.0 and back-extracted into a hydrophilic phase with sodium carbonate (2 mM, pH greater than 10.0). Lactate is detected in the ultraviolet range (242 and 320 nm) by derivatization with alpha-bromoacetophenone. Control plasma samples were studied after an overnight fast for precision and analytical recovery. Calibration curves were linear in the range 0.18-6.0 mM (r = 0.92). The precision was 3% and the analytical recovery was 87%. The detection limit of the method was 36 pmol. Determination of lactate metabolism was performed in a patient with chronic congestive heart failure who was administered primed-continuous L-[U-14C]lactate (10 microCi bolus and 0.3 microCi/min continuously) during a 60-min rest period. Mean arterial lactate concentration and SA were 1.69 +/- 0.2 mM and 253.8 +/- 22 dpm/mumol, respectively. Systemic lactate turnover was 25.65 mumol/kg per min. Lactic acid systemic turnover, organ uptake and release rates can be accurately determined by isocratic HPLC.

  6. Comparison of NCEP performance specifications for triglycerides, HDL-, and LDL-cholesterol with operating specifications based on NCEP clinical and analytical goals.

    Science.gov (United States)

    Fallest-Strobl, P C; Olafsdottir, E; Wiebe, D A; Westgard, J O

    1997-11-01

    The National Cholesterol Education Program (NCEP) performance specifications for methods that measure triglycerides, HDL-cholesterol, and LDL-cholesterol have been evaluated by deriving operating specifications from the NCEP analytical total error requirements and the clinical requirements for interpretation of the tests. We determined the maximum imprecision and inaccuracy that would be allowable to control routine methods with commonly used single and multirule quality-control procedures having 2 and 4 control measurements per run, and then compared these estimates with the NCEP guidelines. The NCEP imprecision specifications meet the operating imprecision necessary to assure meeting the NCEP clinical quality requirements for triglycerides and HDL-cholesterol but not for LDL-cholesterol. More importantly, the NCEP imprecision specifications are not adequate to assure meeting the NCEP analytical total error requirements for any of these three tests. Our findings indicate that the NCEP recommendations fail to adequately consider the quality-control requirements necessary to detect medically important systematic errors.

  7. High performance wash-free magnetic bioassays through microfluidically enhanced particle specificity.

    Science.gov (United States)

    Bechstein, Daniel J B; Lee, Jung-Rok; Ooi, Chin Chun; Gani, Adi W; Kim, Kyunglok; Wilson, Robert J; Wang, Shan X

    2015-06-30

    Magnetic biosensors have emerged as a sensitive and versatile platform for high performance medical diagnostics. These magnetic biosensors require well-tailored magnetic particles as detection probes, which need to give rise to a large and specific biological signal while showing very low nonspecific binding. This is especially important in wash-free bioassay protocols, which do not require removal of particles before measurement, often a necessity in point of care diagnostics. Here we show that magnetic interactions between magnetic particles and magnetized sensors dramatically impact particle transport and magnetic adhesion to the sensor surfaces. We investigate the dynamics of magnetic particles' biomolecular binding and magnetic adhesion to the sensor surface using microfluidic experiments. We elucidate how flow forces can inhibit magnetic adhesion, greatly diminishing or even eliminating nonspecific signals in wash-free magnetic bioassays, and enhancing signal to noise ratios by several orders of magnitude. Our method is useful for selecting and optimizing magnetic particles for a wide range of magnetic sensor platforms.

  8. Perinatal exposure to dioxins perturbs learning performance of the rat in a dose-specific fashion

    Energy Technology Data Exchange (ETDEWEB)

    Hojo, R.; Rieko, H.; Masaki, K.; Junzo, Y.; Chiharu, T. [National Inst. for Environmental Studies, Tsukuba (Japan)

    2004-09-15

    Dioxins (chlorinated dibenzo-p-dioxin congeners and related compounds including coplanar PCBs) are transferred transplacentally and lactationally from mothers to the developing brain of offspring. Maternal exposure to dioxins are suspected to cause adverse effects on the advanced brain function of offspring, because Previous studies indicate that the most toxic dioxin congener, 2,3,7,8-tetrachloro-dibenzo-p-dioxin (TCDD), affected the advanced brain function of rats, even when mothers had been exposed to a relatively low level of dioxins that would not affect themselves. In coplanar PCBs, which are dioxin-like, toxic equivalency factors (TEFs) are based on similar toxicity to TCDD and on a common mechanism of action, mediated by the aromatic hydrocarbon receptor (AhR). However, non-coplanar PCBs, which are considered to be non-dioxin-like PCBs, also show adverse effects on the learning and memory functions of offspring. In the present study, we hypothesize that coplanar PCBs have two types of toxicities, one is the similar to TCDD and the other is the specific toxicity of PCB itself. To address this hypothesis, effects of maternal exposure to one of the coplanar PCBs, 3,3',4,4',5-pentachlorobiphenyl (PCB126, 1997 WHO TEF = 0.1), on learning and behavioural performance of rats assessed by schedule-controlled operant behavior (SCOB) were examined and compared to TCDD.

  9. Effect of Half Time Cooling on Thermoregulatory Responses and Soccer-Specific Performance Tests

    Directory of Open Access Journals (Sweden)

    Yang Zhang

    2014-03-01

    Full Text Available This study examined two active coolings (forearm and hand cooling, and neck cooling during a simulated half-time recovery on thermoregulatory responses and subsequent soccer-specific exercise performance. Following a 45-min treadmill run in the heat, participants (N=7 undertook 15-min recovery with either passive cooling, forearm and hand cooling, or neck cooling in a simulated cooled locker room environment. After the recovery, participants performed a 6×15-m sprint test and Yo-Yo Intermittent Recovery Level 1 test (YYIR1 in a temperate environment. During the 15-min recovery, rectal temperature fell significantly (p<0.05. Neither active coolings induced further reduction in rectal temperature compared to passive cooling. No effect of active coolings was found in repeated sprint test. However, neck cooling reduced (p<0.05 the thermal sensation (TS compared to passive cooling during the 15-min recovery. Active coolings attenuated (p<0.05 the sweat rate compared to passive cooling: 1.2±0.3 l•h-1 vs. 0.8±0.1 l•h-1 vs. 0.8±0.3 l•h-1, for passive cooling, forearm and hand cooling, and neck cooling, respectively. For passive cooling, elevated sweat rate resulted in higher (p<0.05 dehydration (2.1±0.3% compared to neck cooling (1.5±0.3% and forearm and hand cooling (1.4±0.3%. YYIR1 was improved (p<0.05 following forearm and hand cooling (869±320 m and neck cooling (814±328 m compared to passive cooling (654±311 m. Neck cooling (4.6±0.6 reduced (p=0.03 the session TS compared to passive cooling (5.3±0.5. These results suggest that active coolings effectively improved comfort and sweating response, which delayed exercise-heat induced performance diminish during a second bout of exercise.

  10. Preliminary Studies of the Performance of Quinoa (Chenopodium quinoa Willd.) Genotypes under Irrigated and Rainfed Conditions of Central Malawi.

    Science.gov (United States)

    Maliro, Moses F A; Guwela, Veronica F; Nyaika, Jacinta; Murphy, Kevin M

    2017-01-01

    The goal of sustainable intensification of agriculture in Malawi has led to the evaluation of innovative, regionally novel or under-utilized crop species. Quinoa (Chenopodium quinoa Willd.) has the potential to provide a drought tolerant, nutritious alternative to maize. We evaluated 11 diverse varieties of quinoa for their yield and agronomic performance at two locations, Bunda and Bembeke, in Malawi. The varieties originated from Ecuador, Chile and Bolivia in South America; the United States and Canada in North America; and, Denmark in Europe, and were chosen based on their variation in morphological and agronomic traits, and their potential for adaptation to the climate of Malawi. Plant height, panicle length, days to maturity, harvest index, and seed yield were recorded for each variety under irrigation at Bunda and Bembeke, and under rainfed conditions at Bunda. Plant height was significantly influenced by both genotype and environment. There were also significant differences between the two locations for panicle length whereas genotype and genotype × environment (G × E) interaction were not significantly different. Differences were found for genotype and G × E interaction for harvest index. Notably, differences for genotype, environment and G × E were found for grain yield. Seed yield was higher at Bunda (237-3019 kg/ha) than Bembeke (62-692 kg/ha) under irrigated conditions. The highest yielding genotype at Bunda was Titicaca (3019 kg/ha) whereas Multi-Hued was the highest (692 kg/ha) at Bembeke. Strong positive correlations between seed yield and (1) plant height (r = 0.74), (2) days to maturity (r = 0.76), and (3) biomass (r = 0.87) were found under irrigated conditions. The rainfed evaluations at Bunda revealed significant differences in seed yield, plant biomass, and seed size among the genotypes. The highest yielding genotype was Black Seeded (2050 kg/ha) followed by Multi-Hued (1603 kg/ha) and Bio-Bio (1446 kg/ha). Ecuadorian (257 kg/ha) was the

  11. Performance characteristics of selected immunoassays for preliminary test of 3,4-methylenedioxymethamphetamine, methamphetamine, and related drugs in urine specimens.

    Science.gov (United States)

    Hsu, Jui; Liu, Chiareiy; Liu, C P; Tsay, Wen-Ing; Li, Jih-Heng; Lin, Dong-Liang; Liu, Ray H

    2003-10-01

    Eight commercially available immunoassays for amphetamines (DRI Amphetamines, CEDIA DAU Amphetamines-Semiquantitative, EMIT d.a.u. Monoclonal Amphetamine/Methamphetamine, Synchron CX Systems AMPH, TDx/TDxFLx Amphetamine/Methamphetamine II, CEDIA Amphetamines/Ecstasy, COBAS INTEGRA Amphetamines, and Abuscreen((R)) OnLine HS Amphetamine/MDMA) are evaluated for their effectiveness in serving as the preliminary test methodology for the analysis of 3,4-methylenedioxymethamphetamine/3,4-methylenedioxyamphetamine (MDMA/MDA) and methamphetamine/amphetamine (MA/AM). Standard solutions (in urine matrix) of MDMA, MDA, MA, and AM are used to determine these immunoassays' reactivities (or cross-reactivities) toward these compounds of interest. Case specimens containing MDMA/MDA and MA/AM are also used to study the correlations of the apparent immunoassay MDMA (or MA) concentrations and the gas chromatographic-mass spectrometric concentrations of these compounds. Data resulting from this study suggest that CEDIA Amphetamines/Ecstasy can best predict the concentrations of MDMA and MA in case specimens and can also detect the presence of MDMA at low levels, whereas Abuscreen OnLine HS Amphetamine/MDMA can detect both MDMA and MA at low concentrations.

  12. Critical Velocity Is Associated With Combat-Specific Performance Measures in a Special Forces Unit.

    Science.gov (United States)

    Hoffman, Mattan W; Stout, Jeffrey R; Hoffman, Jay R; Landua, Geva; Fukuda, David H; Sharvit, Nurit; Moran, Daniel S; Carmon, Erez; Ostfeld, Ishay

    2016-02-01

    The purpose of this study was to examine the relationship between critical velocity (CV) and anaerobic distance capacity (ADC) to combat-specific tasks (CST) in a special forces (SFs) unit. Eighteen male soldiers (mean ± SD; age: 19.9 ± 0.8 years; height: 177.6 ± 6.6 cm; body mass: 74.1 ± 5.8 kg; body mass index [BMI]: 23.52 ± 1.63) from an SF unit of the Israel Defense Forces volunteered to complete a 3-minute all-out run along with CST (2.5-km run, 50-m casualty carry, and 30-m repeated sprints with "rush" shooting [RPTDS]). Estimates of CV and ADC from the 3-minute all-out run were determined from data downloaded from a global position system device worn by each soldier, with CV calculated as the average velocity of the final 30 seconds of the run and ADC as the velocity-time integral above CV. Critical velocity exhibited significant negative correlations with the 2.5-km run time (r = -0.62, p velocity during the 2.5-km run (r = 0.64, p < 0.01). Stepwise regression identified CV as the most significant performance measure associated with the 2.5-km run time, whereas BMI and CV measures were significant predictors of RPTDS time (R(2) = 0.67, p ≤ 0.05). Using the 3-minute all-out run as a testing measurement in combat, personnel may offer a more efficient and simpler way in assessing both aerobic and anaerobic capabilities (CV and ADC) within a relatively large sample.

  13. Sex-specific sleep patterns among university students in Lebanon: impact on depression and academic performance.

    Science.gov (United States)

    Kabrita, Colette S; Hajjar-Muça, Theresa A

    2016-01-01

    Good sleep quality and quantity are fundamental to the maintenance of normal physiological processes. Changes in sleep patterns are commonly observed among young adults and are shown to impact neurocognitive, academic, and psychological well-being. Given the scarcity of sleep information about Lebanon and acknowledging the sex differences in various sleep dimensions, we conducted a study that aimed at assessing sex differences in sleep habits among university students in Lebanon in relation to psychoacademic status. A total of 540 students (50.6% females) completed a questionnaire that inquired about sociodemographics and evaluated sleep quality and depression using the Pittsburg Sleep Quality Index (PSQI) and Center for Epidemiological Studies Depression Scale (CES-D), respectively. The mean PSQI global score (6.57±3.49) indicated poor sleep, with no significant differences between men and women. The sleep/wake rhythm was delayed on weekends for both sexes. Females exhibited earlier bedtimes and rise times and longer sleep durations on both weekdays and weekends. However, unlike males females showed a greater phase delay in wake times than bedtimes on weekends (149 minutes vs 74 minutes, respectively). In all, 70.9% of females suffered from depressive symptoms, which was a significantly higher proportion compared with 58.5% of males (Pacademic performance of females was significantly better than that of males (2.8±0.61 vs 2.65±0.61, Psex differences in sleep timing, such as bedtime/rise time and nocturnal sleep duration, rather than sleep quality exist among Lebanese university students. Sex-specific sleep patterns have differential impact on psychological and academic well-being.

  14. Analytic bias specifications based on the analysis of effects on performance of medical guidelines.

    Science.gov (United States)

    Klee, G G; Schryver, P G; Kisabeth, R M

    1999-11-01

    Laboratory tests are key indicators for certain practice guidelines, and analytic bias can significantly alter the performance of these guidelines. Three clinical paradigms are described: serum cholesterol testing for risk assessment of cardiac disease, serum thyroid-stimulating hormone (TSH) measurement for the detection of hypothyroidism, and serum prostate-specific antigen (PSA) testing for prostate cancer risk assessment. Maximum tolerance limits for analytic bias are calculated by assessing the subgroup population fluctuations in the number of patients exceeding the guideline threshold values and limiting the analytic bias to one-half of these fluctuations. Our calculated maximum bias limits are +/-1% for cholesterol and +/-6% for TSH and PSA. Our recommended +/-1% bias limit for cholesterol allows for a -6.5% to + 5.8% change in the number of patients designated as at risk for cardiac disease, whereas the +/-3% National Cholesterol Education Program limits permit a -18.4% to +16.7% variation. Similarly, our +/-6% bias limits for TSH allow a -17.7% to +26.6% change in patients flagged for hypothyroidism, whereas the +/-10% bias values found with many commercial reagents permit a -28.2% to +49.2% variation in patient classification. Our +/-6% PSA bias limits correspond to changes from -14.2% to +11.4% in the number of men classified as at risk for prostate cancer. The +/-10% bias ranges for PSA correspond to -19.9% to +20.4% variation in patient classification. The larger tolerance limits of the CLIA-88 standards for proficiency testing would cause even wider variations in patient classifications.

  15. Obstacle avoidance, visual detection performance, and eye-scanning behavior of glaucoma patients in a driving simulator: a preliminary study

    NARCIS (Netherlands)

    Prado Vega, R.; Van Leeuwen, P.M.; Rendon Velez, E.; Lemij, H.G.; De Winter, J.C.

    2013-01-01

    The objective of this study was to evaluate differences in driving performance, visual detection performance, and eye-scanning behavior between glaucoma patients and control participants without glaucoma. Glaucoma patients (n = 23) and control participants (n = 12) completed four 5-min driving sessi

  16. Obstacle avoidance, visual detection performance, and eye-scanning behavior of glaucoma patients in a driving simulator: a preliminary study

    NARCIS (Netherlands)

    Prado Vega, R.; Van Leeuwen, P.M.; Rendon Velez, E.; Lemij, H.G.; De Winter, J.C.

    2013-01-01

    The objective of this study was to evaluate differences in driving performance, visual detection performance, and eye-scanning behavior between glaucoma patients and control participants without glaucoma. Glaucoma patients (n = 23) and control participants (n = 12) completed four 5-min driving sessi

  17. Comparing effects of tillage treatments performed with animal traction on soil physical properties and soil electrical resistivity: preliminary experimental results

    Directory of Open Access Journals (Sweden)

    García-Tomillo Aitor

    2017-02-01

    Full Text Available Soil Compaction results from compressive forces applied to compressible soil by machinery wheels, combined with tillage operations. Draft animal‐pulled equipment may also cause soil compaction, but a huge gap exists on experimental data to adequately assess their impacts and, actually, animal traction is an option seen with increasing potential to contribute to sustainable agriculture, especially in mountain areas. This study was conducted to assess the impacts on soil compaction of tillage operations with motor tractor and draft animals. In a farm plot (Vale de Frades, NE Portugal treatments were applied in sub‐plots (30 m × 3 m, consisting in a two way tillage with tractor (T, a pair of cows (C and a pair of donkeys (D. Undisturbed soil samples (120 were taken before and after operations for bulk density (BD and saturated hydraulic conductivity (Ks. The relative changes in BD observed after tillage in the 0-0.05 m soil depth increased after operations in all treatments. The increase was higher in the tractor sub-plot (15% than in those where animal traction was used (8%. Before operation Ks class was rapid and fast in all samples, and after operation this value was reduced to 33% in T, whereas it reached 83% in C. Electrical Resistivity Tomography (ERT was useful as a tool to identify the alterations caused by tillage operations on soil physical status. These preliminary results confirm the potential of animal traction as an option for mountain agri‐environments, yet it requires much wider research to soundly ground its assets.

  18. Large Area X-Ray Proportional Counter (LAXPC) Instrument on AstroSat and Some Preliminary Results from its Performance in the Orbit

    Indian Academy of Sciences (India)

    P. C. Agrawal; J. S. Yadav; H. M. Antia; Dhiraj Dedhia; P. Shah; Jai Verdhan Chauhan; R. K. Manchanda; V. R. Chitnis; V. M. Gujar; Tilak Katoch; V. N. Kurhade; P. Madhwani; T. K. Manojkumar; V. A. Nikam; A. S. Pandya; J. V. Parmar; D. M. Pawar; Jayashree Roy; B. Paul; Mayukh Pahari; Ranjeev Misra; M. H. Ravichandran; K. Anilkumar; C. C. Joseph; K. H. Navalgund; R. Pandiyan; K. S. Sarma; K. Subbarao

    2017-06-01

    Large area X-ray propositional counter (LAXPC) instrument on AstroSat is aimed at providing high time resolution X-ray observations in 3–80 keV energy band with moderate energy resolution. To achieve large collecting area, a cluster of three co-aligned identical LAXPC detectors, is used to realize an effective area in access of ∼6000cm2 at 15 keV. The large detection volume of the LAXPC detectors, filled with xenon gas at ∼2 atmosphere pressure, results in detection efficiency greater than 50%, above 30 keV. In this article, we present salient features of the LAXPC detectors, their testing and characterization in the laboratory prior to launch and calibration in the orbit. Some preliminary results on timing and spectral characteristics of a few X-ray binaries and other type of sources, are briefly discussed to demonstrate that the LAXPC instrument is performing as planned in the orbit.

  19. Development and evaluation of the LiSN & learn auditory training software for deficit-specific remediation of binaural processing deficits in children: preliminary findings.

    Science.gov (United States)

    Cameron, Sharon; Dillon, Harvey

    2011-01-01

    The LiSN & Learn auditory training software was developed specifically to improve binaural processing skills in children with suspected central auditory processing disorder who were diagnosed as having a spatial processing disorder (SPD). SPD is defined here as a condition whereby individuals are deficient in their ability to use binaural cues to selectively attend to sounds arriving from one direction while simultaneously suppressing sounds arriving from another. As a result, children with SPD have difficulty understanding speech in noisy environments, such as in the classroom. To develop and evaluate the LiSN & Learn auditory training software for children diagnosed with the Listening in Spatialized Noise-Sentences Test (LiSN-S) as having an SPD. The LiSN-S is an adaptive speech-in-noise test designed to differentially diagnose spatial and pitch-processing deficits in children with suspected central auditory processing disorder. Participants were nine children (aged between 6 yr, 9 mo, and 11 yr, 4 mo) who performed outside normal limits on the LiSN-S. In a pre-post study of treatment outcomes, participants trained on the LiSN & Learn for 15 min per day for 12 weeks. Participants acted as their own control. Participants were assessed on the LiSN-S, as well as tests of attention and memory and a self-report questionnaire of listening ability. Performance on all tasks was reassessed after 3 mo where no further training occurred. The LiSN & Learn produces a three-dimensional auditory environment under headphones on the user's home computer. The child's task was to identify a word from a target sentence presented in background noise. A weighted up-down adaptive procedure was used to adjust the signal level of the target based on the participant's response. On average, speech reception thresholds on the LiSN & Learn improved by 10 dB over the course of training. As hypothesized, there were significant improvements in posttraining performance on the LiSN-S conditions

  20. Sex-specific sleep patterns among university students in Lebanon: impact on depression and academic performance

    Directory of Open Access Journals (Sweden)

    Kabrita CS

    2016-06-01

    Full Text Available Colette S Kabrita,1 Theresa A Hajjar-Muça,2 1Department of Sciences, 2Department of Mathematics and Statistics, Faculty of Natural and Applied Sciences, Notre Dame University – Louaize, Zouk Mosbeh, Lebanon Abstract: Good sleep quality and quantity are fundamental to the maintenance of normal physiological processes. Changes in sleep patterns are commonly observed among young adults and are shown to impact neurocognitive, academic, and psychological well-being. Given the scarcity of sleep information about Lebanon and acknowledging the sex differences in various sleep dimensions, we conducted a study that aimed at assessing sex differences in sleep habits among university students in Lebanon in relation to psychoacademic status. A total of 540 students (50.6% females completed a questionnaire that inquired about sociodemographics and evaluated sleep quality and depression using the Pittsburg Sleep Quality Index (PSQI and Center for Epidemiological Studies Depression Scale (CES-D, respectively. The mean PSQI global score (6.57±3.49 indicated poor sleep, with no significant differences between men and women. The sleep/wake rhythm was delayed on weekends for both sexes. Females exhibited earlier bedtimes and rise times and longer sleep durations on both weekdays and weekends. However, unlike males females showed a greater phase delay in wake times than bedtimes on weekends (149 minutes vs 74 minutes, respectively. In all, 70.9% of females suffered from depressive symptoms, which was a significantly higher proportion compared with 58.5% of males (P<0.01. Based on the mean cumulative self-reported grade point average (GPA, the academic performance of females was significantly better than that of males (2.8±0.61 vs 2.65±0.61, P<0.05, respectively. Depression, as scored by CES-D, in females was significantly negatively correlated with the cumulative GPA (r=-0.278, P<0.01, earlier wake time (r=-0.168, P<0.05, and average sleep duration (r=-0

  1. The effect of single-task and dual-task balance exercise programs on balance performance in adults with osteoporosis: a randomized controlled preliminary trial.

    Science.gov (United States)

    Konak, H E; Kibar, S; Ergin, E S

    2016-11-01

    Osteoporosis is a serious disease characterized by muscle weakness in the lower extremities, shortened length of trunk, and increased dorsal kyphosis leading to poor balance performance. Although balance impairment increases in adults with osteoporosis, falls and fall-related injuries have been shown to occur mainly during the dual-task performance. Several studies have shown that dual-task performance was improved with specific repetitive dual-task exercises.

  2. A preliminary investigation into the relationship between functional movement screen scores and athletic physical performance in female team sport athletes.

    Science.gov (United States)

    Lockie, Rg; Schultz, Ab; Callaghan, Sj; Jordan, Ca; Luczo, Tm; Jeffriess, Md

    2015-03-01

    There is little research investigating relationships between the Functional Movement Screen (FMS) and athletic performance in female athletes. This study analyzed the relationships between FMS (deep squat; hurdle step [HS]; in-line lunge [ILL]; shoulder mobility; active straight-leg raise [ASLR]; trunk stability push-up; rotary stability) scores, and performance tests (bilateral and unilateral sit-and-reach [flexibility]; 20-m sprint [linear speed]; 505 with turns from each leg; modified T-test with movement to left and right [change-of-direction speed]; bilateral and unilateral vertical and standing broad jumps; lateral jumps [leg power]). Nine healthy female recreational team sport athletes (age = 22.67 ± 5.12 years; height = 1.66 ± 0.05 m; body mass = 64.22 ± 4.44 kilograms) were screened in the FMS and completed the afore-mentioned tests. Percentage between-leg differences in unilateral sit-and-reach, 505 turns and the jumps, and difference between the T-test conditions, were also calculated. Spearman's correlations (p ≤ 0.05) examined relationships between the FMS and performance tests. Stepwise multiple regressions (p ≤ 0.05) were conducted for the performance tests to determine FMS predictors. Unilateral sit-and-reach positive correlated with the left-leg ASLR (r = 0.704-0.725). However, higher-scoring HS, ILL, and ASLR related to poorer 505 and T-test performance (r = 0.722-0.829). A higher-scored left-leg ASLR related to a poorer unilateral vertical and standing broad jump, which were the only significant relationships for jump performance. Predictive data tended to confirm the correlations. The results suggest limitations in using the FMS to identify movement deficiencies that could negatively impact athletic performance in female team sport athletes.

  3. A preliminary investigation into the relationship between functional movement screen scores and athletic physical performance in female team sport athletes

    Directory of Open Access Journals (Sweden)

    Robert G Lockie

    2014-11-01

    Full Text Available There is little research investigating relationships between the Functional Movement Screen (FMS and athletic performance in female athletes. This study analyzed the relationships between FMS (deep squat; hurdle step [HS]; in-line lunge [ILL]; shoulder mobility; active straight-leg raise [ASLR]; trunk stability push-up; rotary stability scores, and performance tests (bilateral and unilateral sit-and-reach [flexibility]; 20-m sprint [linear speed]; 505 with turns from each leg; modified T-test with movement to left and right [change-of-direction speed]; bilateral and unilateral vertical and standing broad jumps; lateral jumps [leg power]. Nine healthy female recreational team sport athletes (age = 22.67 ± 5.12 years; height = 1.66 ± 0.05 m; body mass = 64.22 ± 4.44 kilograms were screened in the FMS and completed the afore-mentioned tests. Percentage between-leg differences in unilateral sit-and-reach, 505 turns and the jumps, and difference between the T-test conditions, were also calculated. Spearman’s correlations (p ≤ 0.05 examined relationships between the FMS and performance tests. Stepwise multiple regressions (p ≤ 0.05 were conducted for the performance tests to determine FMS predictors. Unilateral sit-and-reach positive correlated with the left-leg ASLR (r = 0.704-0.725. However, higher-scoring HS, ILL, and ASLR related to poorer 505 and T-test performance (r = 0.722-0.829. A higher-scored left-leg ASLR related to a poorer unilateral vertical and standing broad jump, which were the only significant relationships for jump performance. Predictive data tended to confirm the correlations. The results suggest limitations in using the FMS to identify movement deficiencies that could negatively impact athletic performance in female team sport athletes.

  4. Preliminary Analysis of the Museum Performance Appraisal System%博物馆绩效考核体系初探

    Institute of Scientific and Technical Information of China (English)

    韩宁

    2012-01-01

    本文着眼于探索如何建立属于博物馆的科学合理的绩效考核体系,分别从博物馆绩效考核的国际化趋势、我国博物馆引入绩效考核的紧迫性、博物馆绩效考核体系分析等三个方面进行了阐述,表明博物馆绩效考核是一种国际化行为。在我国博物馆免费开放之后,建立科学合理的绩效考核体系,有助于促进博物馆内部管理、绩效水平、服务质量及公众-社会满意度的整体提升,使其成为深化博物馆管理体制改革的一种有效尝试。%This paper focuses on how to establish a scientific and reasonable museum performance evaluation system.This issue is discussed in three aspects,such as the international trend of the museum performance appraisal,the urgency of introducing the performance appraisal system into the museum management and the analysis of the performance appraisal system.Obviously,the museum performance assessment is a kind of international behavior.The establishment of the scientific and reasonable performance appraisal system is helpful to comprehensively promote the interior management of the museum,the measurement of its performance,as well as its quality of service and social satisfaction.It is an effective and valuable attempt to deepen the reform of the museum management system.

  5. A methodical approach to performance measurement experiments : measure and measurement specification

    OpenAIRE

    Hoeksema, F.W.; Veen,, A. m.; Beijnum, van, B.J.F.

    1997-01-01

    This report describes a methodical approach to performance measurement experiments. This approach gives a blueprint for the whole trajectory from the notion of performance measures and how to define them via planning, instrumentation and execution of the experiments to interpretation of the results. The first stage of the approach, Measurement Initialisation, has been worked out completely. It is shown that a well-defined system description allows a procedural approach to defining performance...

  6. DECOVALEX-THMC Project. Task A. Influence of near field coupled THM phenomena on the performance of a spent fuel repository. Report of Task A1: Preliminary scoping calculations

    Energy Technology Data Exchange (ETDEWEB)

    Nguyen, Son (ed.) [Canadian Nuclear Safety Commission (Canada); Lanru Jing (ed.) [Royal Institute of Technology, Stockholm (Sweden); Boergesson, Lennart [Clay Technology AB, Lund (Sweden); Chijimatzu, Masakazu [Hazama Corporation (Japan); Jussila, Petri [Helsinki Univ. of Technology, Helsinki (Finland); Rutqvist, Jonny [Lawrence Berkeley National Laboratory CA (United States)

    2007-02-15

    The DECOVALEX-THMC project is an ongoing international co-operative project that was stared in 2004 to support the development of mathematical models of coupled Thermal (T), Hydrological (H), Mechanical (M) and Chemical (C) processes in geological media for siting potential nuclear fuel waste repositories. The general objective is to characterise and evaluate the coupled THMC processes in the near field and far field of a geological repository and to assess their impact on performance assessment: - during the three phases of repository development: excavation phase, operation phase and post-closure phase; - for three different rocks types: crystalline, argillaceous and tuff; - with specific focus on the issues of: Excavation Damaged Zone (EDZ), permanent property changes of rock masses, and glaciation and permafrost phenomena. The project involves a large number of research teams supported by radioactive waste management agencies or governmental regulatory bodies in Canada, China, Finland, France, Germany, Japan, Sweden and USA, who conducted advanced studies and numerical modelling of coupled THMC processes under five tasks. This report presents the definition of the first phase, Task A-1, of the Task A of the project. The task is a working example of how interaction between THMC modelling and SA analysis could be performed. Starting with the technical definition of the Task A, the report presents the results of preliminary THM calculations with a purpose of an initial appreciation of the phenomena and material properties that must be better understood in subsequent phases. Many simplifications and assumptions were introduced and the results should be considered under these assumptions. Based on the evaluation of the multiple teams' results, a few points of concern were identified that may guide the successive phases of Task A studies: 1. The predicted maximum total stress in the MX-80 bentonite could slightly exceed the 15 MPa design pressure for the

  7. Productive High Performance Parallel Programming with Auto-tuned Domain-Specific Embedded Languages

    Science.gov (United States)

    2013-01-02

    ECL Embedded Common Lisp EM Expectation-Maximization FFI Foreign Function Interface FFT Fast Fourier Transform FFTW Fastest Fourier Transform in the...results to the user. 3.3 Domain-Specific Embedded Languages Domain-specific embedded languages are used in many programming languages such as Lisp ...designed to be extensible using metaprogramming, including Haskell and variants of Lisp . These DSELs generally transformed host language code into

  8. A preliminary examination of neurocognitive performance and symptoms following a bout of soccer heading in athletes wearing protective soccer headbands.

    Science.gov (United States)

    Elbin, R J; Beatty, Amanda; Covassin, Tracey; Schatz, Philip; Hydeman, Ana; Kontos, Anthony P

    2015-01-01

    This study compared changes in neurocognitive performance and symptom reports following an acute bout of soccer heading among athletes with and without protective soccer headgear. A total of 25 participants headed a soccer ball 15 times over a 15-minute period, using a proper linear heading technique. Participants in the experimental group completed the heading exercise while wearing a protective soccer headband and controls performed the heading exercise without wearing the soccer headband. Neurocognitive performance and symptom reports were assessed before and after the acute bout of heading. Participants wearing the headband showed significant decreases on verbal memory (p = 0.02) compared with the no headband group, while the no headband group demonstrated significantly faster reaction time (p = 0.03) than the headband group following the heading exercise. These findings suggest that protective soccer headgear likely does not mitigate the subtle neurocognitive effects of acute soccer heading.

  9. Comparison of force, power, and striking efficiency for a Kung Fu strike performed by novice and experienced practitioners: preliminary analysis.

    Science.gov (United States)

    Neto, Osmar Pinto; Magini, Marcio; Saba, Marcelo M F; Pacheco, Marcos Tadeu Tavares

    2008-02-01

    This paper presents a comparison of force, power, and efficiency values calculated from Kung Fu Yau-Man palm strikes, when performed by 7 experienced and 6 novice men. They performed 5 palm strikes to a freestanding basketball, recorded by high-speed camera at 1000 Hz. Nonparametric comparisons and correlations showed experienced practitioners presented larger values of mean muscle force, mean impact force, mean muscle power, mean impact power, and mean striking efficiency, as is noted in evidence obtained for other martial arts. Also, an interesting result was that for experienced Kung Fu practitioners, muscle power was linearly correlated with impact power (p = .98) but not for the novice practitioners (p = .46).

  10. Preliminary assessment of accident-tolerant fuels on LWR performance during normal operation and under DB and BDB accident conditions

    Science.gov (United States)

    Ott, L. J.; Robb, K. R.; Wang, D.

    2014-05-01

    Following the severe accidents at the Japanese Fukushima Daiichi Nuclear Power Station in 2011, the US Department of Energy initiated research and development on the enhancement of the accident tolerance of light water reactors by the development of fuels/cladding that, in comparison with the standard UO2/Zircaloy (Zr) system, can tolerate loss of active cooling in the core for a considerably longer time period while maintaining or improving the fuel performance during normal operations. Analyses are presented that illustrate the impact of these new candidate fuel/cladding materials on the fuel performance at normal operating conditions and on the reactor system under DB and BDB accident conditions.

  11. A Specific Model for Assessing the Financial Performance:Case study on Building Sector Enterprises of Galati County - Romania

    Directory of Open Access Journals (Sweden)

    Nicoleta BARBUTA-MISU

    2011-11-01

    Full Text Available In this paper is designed a specific model for assessing the financial performance, based on models of bankruptcy risk, for enterprises acting in the building sector from Galati County - Romania. The main purpose of the paper is designing and development a model for evaluation financial performance that important for ranking enterprises. To choose model variables was used discriminate analysis on 22 variables proposed that separate objectively performant by non-performant enterprises. The proposed model with five variables was tested using the initial sample of enterprises obtaining an average success ratio of 81.82%.

  12. A methodical approach to performance measurement experiments : measure and measurement specification

    NARCIS (Netherlands)

    Hoeksema, F.W.; Veen, van der J.T.; Beijnum, van B.J.F.

    1997-01-01

    This report describes a methodical approach to performance measurement experiments. This approach gives a blueprint for the whole trajectory from the notion of performance measures and how to define them via planning, instrumentation and execution of the experiments to interpretation of the results.

  13. A Methodical Approach to Performance Measurement Experiments: Measure and Measurement Specification

    NARCIS (Netherlands)

    Hoeksema, F.W.; van der Veen, Johan (CTIT); van Beijnum, Bernhard J.F.

    1997-01-01

    This report describes a methodical approach to performance measurement experiments. This approach gives a blueprint for the whole trajectory from the notion of performance measures and how to define them via planning, instrumentation and execution of the experiments to interpretation of the results.

  14. Variable interaction specificity and symbiont performance in Panamanian Trachymyrmex and Sericomyrmex fungus-growing ants

    DEFF Research Database (Denmark)

    de Fine Licht, Henrik Hjarvard; Boomsma, Jacobus Jan

    2014-01-01

    Background Cooperative benefits of mutualistic interactions are affected by genetic variation among the interacting partners, which may have consequences for interaction-specificities across guilds of sympatric species with similar mutualistic life histories. The gardens of fungus-growing (attine...... and Sericomyrmex higher attine ants in Gamboa, Panama provided the opportunity to do a quantitative study of species-level interaction-specificity. Results We genotyped the ants for Cytochrome Oxidase and their Leucoagaricus fungal cultivars for ITS rDNA. Combined with activity measurements for 12 carbohydrate...... cultivar symbiont-specificity varied from almost full symbiont sharing to one-to-one specialization, suggesting that trade-offs between enzyme activity spectra and life-history traits such as desiccation tolerance, disease susceptibility and temperature sensitivity may apply in some combinations...

  15. Improving Performance in Constructing specific Web Directory using Focused Crawler: An Experiment on Botany Domain

    Science.gov (United States)

    Khalilian, Madjid; Boroujeni, Farsad Zamani; Mustapha, Norwati

    Nowadays the growth of the web causes some difficulties to search and browse useful information especially in specific domains. However, some portion of the web remains largely underdeveloped, as shown in lack of high quality contents. An example is the botany specific web directory, in which lack of well-structured web directories have limited user's ability to browse required information. In this research we propose an improved framework for constructing a specific web directory. In this framework we use an anchor directory as a foundation for primary web directory. This web directory is completed by information which is gathered with automatic component and filtered by experts. We conduct an experiment for evaluating effectiveness, efficiency and satisfaction.

  16. Therapists' and patients' stress responses during graduated versus flooding in vivo exposure in the treatment of specific phobia: A preliminary observational study.

    Science.gov (United States)

    Schumacher, Sarah; Miller, Robert; Fehm, Lydia; Kirschbaum, Clemens; Fydrich, Thomas; Ströhle, Andreas

    2015-12-15

    Exposure therapy is considered an effective treatment strategy for phobic anxiety, however, it is rarely applied in clinical practice. The under-usage might be due to various factors of which heightened stress levels not only in patients but also in therapists are presumed to be of particular relevance. The present study aimed to investigate whether different forms of exposure might lead to varying physiological and psychological stress responses in therapists and phobic patients. 25 patients with specific phobia underwent individual cognitive behavioural therapy, performed by 25 psychotherapist trainees, applying exposure sessions in graduated form or the flooding technique. Patients and therapists provided subjective evaluations of stress and five saliva samples for analysis of salivary cortisol and alpha-amylase either during two graduated exposure sessions or during one flooding session, while a regular therapy session served as control condition. Therapists displayed heightened salivary alpha-amylase release during exposure of the flooding, but not the graduated, type. Patients showed elevated salivary cortisol during flooding exposure numerically, however, not on a statistically significant level. Therapists reported more pronounced subjective stress during flooding compared to graduated exposure. Elevated stress levels should be addressed in clinical training in order to improve application of exposure in routine practice.

  17. Specific physiological and biomechanical performance in elite, sub-elite and in non-elite male team handball players.

    Science.gov (United States)

    Wagner, Herbert; Fuchs, Philip X; von Duvillard, Serge P

    2017-05-30

    Team handball is a dynamic sport game that is played professionally in numerous countries. However, knowledge about training and competition is based mostly on practical experience due to limited scientific studies. Consequently, the aims of our study were to compare specific physiological and biomechanical performance in elite, sub-elite and in non-elite male team handball players. Thirty-six elite, sub-elite and non-elite male team handball players performed a game based performance test, upper-body and lower-body strength tests, 30m sprint test, counter movement jump test and an incremental treadmill running test. Significant differences (Pperformance test, maximal oxygen uptake in the incremental treadmill running test as well as in maximal leg strength and leg explosive strength in the isometric strength test. Elite male players have an enhanced specific agility, a better throwing performance, a higher team handball specific oxygen uptake and higher leg strength compared to sub-elite and non-elite players. Based on these results we recommend that training in team handball should focus on game based training methods to improve performance in specific agility, endurance and technique.

  18. Optimizing the fMRI data-processing pipeline using prediction and reproducibility performance metrics: I. A preliminary group analysis

    DEFF Research Database (Denmark)

    Strother, Stephen C.; Conte, Stephen La; Hansen, Lars Kai

    2004-01-01

    of baseline scans have constant, equal means, and this assumption was assessed with prediction metrics. Higher-order polynomial warps compared to affine alignment had only a minor impact on the performance metrics. We found that both prediction and reproducibility metrics were required for optimizing......We argue that published results demonstrate that new insights into human brain function may be obscured by poor and/or limited choices in the data-processing pipeline, and review the work on performance metrics for optimizing pipelines: prediction, reproducibility, and related empirical Receiver...... Operating Characteristic (ROC) curve metrics. Using the NPAIRS split-half resampling framework for estimating prediction/reproducibility metrics (Strother et al., 2002), we illustrate its use by testing the relative importance of selected pipeline components (interpolation, in-plane spatial smoothing...

  19. Performance in sports - with specific emphasis on the effect of intensified training

    DEFF Research Database (Denmark)

    Bangsbo, Jens

    2015-01-01

    Performance in most sports is determined by the athlete's technical, tactical, physiological and psychological/social characteristics. In the present article, the physical aspect will be evaluated with a focus on what limits performance, and how training can be conducted to improve performance...... with aerobic high-intensity sessions, also performance during longer events. Athletes in team sports involving intense exercise actions and endurance aspects, such as soccer and basketball, can also benefit from intensified training. Speed endurance training does reduce energy expenditure and increase...... expression of muscle Na(+) , K(+) pump α subunits, which may preserve muscle cell excitability and delay fatigue development during intense exercise. When various types of training are conducted in the same period (concurrent training), as done in a number of sports, one type of training may blunt the effect...

  20. Packaging produced from natural fibers and mycelium: Optimizing biomass blends to meet performance specifications

    Science.gov (United States)

    Polystyrene is non-biodegradable and has environmental issues associated with its disposal. A replacement for polystyrene that is biodegradable, environmentally friendly, and has similar performance characteristics is of interest to many ecologically minded companies and consumers. This study utiliz...

  1. Breeding performance of carbide and nitride fuels in 2000 MWe LMFBRs: a preliminary report. Part I. Assumptions, constraints and methodology

    Energy Technology Data Exchange (ETDEWEB)

    Barthold, W P

    1976-09-01

    The assumptions, constraints, and methodology used in the design and analysis of 2000 MWe LMFBRs using carbide and nitride fuel are presented. The assumptions used in the nuclear, thermal and mechanical designs are discussed together with geometry constraints, operational constraints, performance constraints, constraints coming from fabrication consideration and fuel bundle-duct interaction constraints. The basic calculational flow for system design studies is described, and the computer codes used in the analyses are briefly reviewed.

  2. Hippocampal atrophy and verbal episodic memory performance in amnestic mild cognitive impairment and mild Alzheimer's disease: A preliminary study

    Directory of Open Access Journals (Sweden)

    Nathalia Carollina Peruzza Marchiani

    Full Text Available Abstract To evaluate hippocampal volume in patients with AD and aMCI, and correlate its atrophy with verbal episodic memory performance. Methods: We studied 42 individuals older than 50 years, including 14 with amnestic mild cognitive impairment (aMCI, 14 with mild Alzheimer's disease (AD and 14 normal controls. All individuals were submitted to the Rey auditory verbal learning test (RAVLT to evaluate episodic memory. They were also submitted to the forward (FDS and backward digit span (BDS subtest of WAIS-R to evaluate working memory and attention, and to the Mini Mental State Examination (MMSE. Hippocampal volumetric measurements were performed according to anatomic guidelines from a standard protocol using high-resolution T1-inversion recovery 3-mm coronal MRI slices. Hippocampal volumes (HV were corrected for the variation in total intracranial volume. There was no significant difference between the three groups concerning age and education. Results: On RAVLT, there was a continuum between the three groups, with AD recalling less words, controls more, and aMCI subjects showing an intermediate performance on all sub-items. We found an asymmetry between HVs, with smaller mean left HV for all groups. ANOVA and post hoc Tukey's test for comparisons of HV showed a significant difference among groups, with difference between controls and both AD and aMCI, although there was no significant difference between AD and aMCI groups. Conclusions: There was a significant correlation between hippocampal volumes and scores on RAVLT, confirming that medial temporal structures are closely associated with memory performance in normal ageing as well as in aMCI and AD.

  3. Study to perform preliminary experiments to evaluate particle generation and characterization techniques for zero-gravity cloud physics experiments

    Science.gov (United States)

    Katz, U.

    1982-01-01

    Methods of particle generation and characterization with regard to their applicability for experiments requiring cloud condensation nuclei (CCN) of specified properties were investigated. Since aerosol characterization is a prerequisite to assessing performance of particle generation equipment, techniques for characterizing aerosol were evaluated. Aerosol generation is discussed, and atomizer and photolytic generators including preparation of hydrosols (used with atomizers) and the evaluation of a flight version of an atomizer are studied.

  4. Specificity matters: criterion-related validity of contextualized and facet measures of conscientiousness in predicting college student performance.

    Science.gov (United States)

    Woo, Sang Eun; Jin, Jing; LeBreton, James M

    2015-01-01

    To enhance the predictive validity of self-report personality measures, 2 distinct ways of increasing specificity of personality measures have been proposed in the literature-contextual specificity (i.e., providing a contextual referent) and content specificity (i.e., focusing on more specific constructs such as the Big Five facets). This study extends this line of research by examining whether there is an optimal way to configure, align, or integrate contextual and content specificity using measures of conscientiousness to predict college student success. A sample of 478 undergraduate students completed 4 measures of conscientiousness that varied in the level of content and contextual specificity. These forms of specificity were crossed to yield 4 distinct measures of conscientiousness. We then evaluated and compared the relative importance and the incremental importance of these different measures in the prediction of academic success. Superior predictive validity was found for both contextualized and facet measures of conscientiousness compared to a measure of global conscientiousness in predicting grade-point average and a broader behavioral criterion of student performance. When contextual and content specificity approaches were compared and combined, we observed the strongest predictive validity when the level of specificity is appropriately matched between predictor and criterion.

  5. Cross-Situational Specificity in Managers’ Perceptions of Subordinate Performance, Attributions, and Leader Behaviors.

    Science.gov (United States)

    1982-05-20

    implicit leadership theories (cf. Eden & Leviatin,1975; Larson, 1982; Lord, Binning, Rush, & Thomas , 197f; Mitchell, Larson, & Green, 1977; Phillips...research: A replication and extension. Organizational Behavior and Human Performance, 1978, 21, 358-366. Eden, D., & Leviatan , U. Implicit leadership theory...theory. Organizational Behavior and Human Performance, 1976, 17, 76-96. Lord, R. G., Binning, J. R., Rush, M. C., & Thomas , J. C. The effects of

  6. Obstacle avoidance, visual detection performance, and eye-scanning behavior of glaucoma patients in a driving simulator: a preliminary study.

    Directory of Open Access Journals (Sweden)

    Rocío Prado Vega

    Full Text Available The objective of this study was to evaluate differences in driving performance, visual detection performance, and eye-scanning behavior between glaucoma patients and control participants without glaucoma. Glaucoma patients (n = 23 and control participants (n = 12 completed four 5-min driving sessions in a simulator. The participants were instructed to maintain the car in the right lane of a two-lane highway while their speed was automatically maintained at 100 km/h. Additional tasks per session were: Session 1: none, Session 2: verbalization of projected letters, Session 3: avoidance of static obstacles, and Session 4: combined letter verbalization and avoidance of static obstacles. Eye-scanning behavior was recorded with an eye-tracker. Results showed no statistically significant differences between patients and control participants for lane keeping, obstacle avoidance, and eye-scanning behavior. Steering activity, number of missed letters, and letter reaction time were significantly higher for glaucoma patients than for control participants. In conclusion, glaucoma patients were able to avoid objects and maintain a nominal lane keeping performance, but applied more steering input than control participants, and were more likely than control participants to miss peripherally projected stimuli. The eye-tracking results suggest that glaucoma patients did not use extra visual search to compensate for their visual field loss. Limitations of the study, such as small sample size, are discussed.

  7. Efficacy of Brain Gym Training on the Cognitive Performance and Fitness Level of Active Older Adults: A Preliminary Study.

    Science.gov (United States)

    Cancela, José M; Vila Suárez, Ma Helena; Vasconcelos, Jamine; Lima, Ana; Ayán, Carlos

    2015-10-01

    This study evaluates the impact of Brain Gym (BG) training in active older adults. Eighty-five participants were assigned to four training groups: BG (n = 18), BG plus water-based exercise (n = 18), land-based exercise (n = 30), and land plus water-based exercise (n = 19). The effects of the programs on the attention and memory functions were assessed by means of the symbol digit modality test. The two-min step and the eight-foot up-and-go tests were used to evaluate their impact on fitness level. No program had a significant influence on the participant's cognitive performance, while different effects on the sample' fitness levels were observed. These findings suggest that the effects of BG on the cognitive performance and fitness level of active older adults are similar to those obtained after the practice of a traditional exercise program. Whether BG is performed in isolation or combined with other exercise programs seems to have no influence on such effects.

  8. C-arm flat-panel CT arthrography of the shoulder: Radiation dose considerations and preliminary data on diagnostic performance

    Energy Technology Data Exchange (ETDEWEB)

    Guggenberger, Roman; Ulbrich, Erika J.; Kaelin, Pascal; Pfammatter, Thomas; Alkadhi, Hatem; Andreisek, Gustav [University Hospital Zurich, Institute of Diagnostic and Interventional Radiology, Zuerich (Switzerland); Dietrich, Tobias J. [Balgrist University Hospital, Department of Radiology, Zurich (Switzerland); Scholz, Rosemarie; Koehler, Christoph; Elsaesser, Thilo [Siemens Healthcare GmbH, Business Area Advanced Therapies, Forchheim (Germany); Le Corroller, Thomas [Aix-Marseille Universite, CNRS, ISM UMR 7287, Marseille (France); Radiology Department, APHM, Marseille (France)

    2017-02-15

    To investigate radiation dose and diagnostic performance of C-arm flat-panel CT (FPCT) versus standard multi-detector CT (MDCT) shoulder arthrography using MRI-arthrography as reference standard. Radiation dose of two different FPCT acquisitions (5 and 20 s) and standard MDCT of the shoulder were assessed using phantoms and thermoluminescence dosimetry. FPCT arthrographies were performed in 34 patients (mean age 44 ± 15 years). Different joint structures were quantitatively and qualitatively assessed by two independent radiologists. Inter-reader agreement and diagnostic performance were calculated. Effective radiation dose was markedly lower in FPCT 5 s (0.6 mSv) compared to MDCT (1.7 mSv) and FPCT 20 s (3.4 mSv). Contrast-to-noise ratios (CNRs) were significantly (p < 0.05) higher in FPCT 20-s versus 5-s protocols. Inter-reader agreements of qualitative ratings ranged between κ = 0.47-1.0. Sensitivities for cartilage and rotator cuff pathologies were low for FPCT 5-s (40 % and 20 %) and moderate for FPCT 20-s protocols (75 % and 73 %). FPCT showed high sensitivity (81-86 % and 89-99 %) for bone and acromioclavicular-joint pathologies. Using a 5-s protocol FPCT shoulder arthrography provides lower radiation dose compared to MDCT but poor sensitivity for cartilage and rotator cuff pathologies. FPCT 20-s protocol is moderately sensitive for cartilage and rotator cuff tendon pathology with markedly higher radiation dose compared to MDCT. (orig.)

  9. Development of Performance-Related Specification for Fresh Emulsions Used for Surface Treatments and Performance Study of Chip Seals and Microsurfacing

    Science.gov (United States)

    Ilias, Mohammad

    Pavement preservation is a rapidly growing strategy for prolonging pavement service life. Pavement preservation consists of applying a thin layer of asphalt binder or emulsion with or without aggregate to the surface of an existing pavement. Preservation treatments do not provide any structural strength to the pavement but restores skid resistance, seals existing cracks, protects the underlying pavement from intrusion of water, and reduces further oxidative aging of the underlying pavement. In recent years, significant research has been dedicated to improving design of pavement preservation treatments. In pavement preservation treatments, asphalt emulsion is the predominant binding material used because of its low viscosity compared to asphalt cement which allows for production at greatly reduced temperatures, leading to energy efficiency, and potential cost savings. Currently, specifications for emulsions used in pavement preservation treatments are empirical and lack of direct relationship to performance. This study seeks to improve specifications for emulsions used in preservation treatments by developing performancerelated specifications (PRS) for (a) fresh emulsion properties, (b) microsurfacing emulsion residue, and (c) low-temperature raveling of chip seal emulsion residues. Fresh emulsion properties dictate constructability and stability, and consequently the resultant performance of a preservation treatment once placed. Specification test methods are proposed for chip seals, microsurfacings, and spray seals that reflect storage and construction conditions of the emulsions. Performance is quantified using viscosity measurements. Specification limits are determined based on a prior knowledge of emulsion performance coupled with statistical analyses. Microsurfacings are a preservation treatment consisting of application of a thin layer of asphalt emulsion -- fine aggregate mixture. Presently, mixture design and performances of microsurfacing mixtures are

  10. Mortality prediction models for pediatric intensive care : comparison of overall and subgroup specific performance

    NARCIS (Netherlands)

    Visser, Idse H. E.; Hazelzet, Jan A.; Albers, Marcel J. I. J.; Verlaat, Carin W. M.; Hogenbirk, Karin; van Woensel, Job B.; van Heerde, Marc; van Waardenburg, Dick A.; Jansen, Nicolaas J. G.; Steyerberg, Ewout W.

    2013-01-01

    To validate paediatric index of mortality (PIM) and pediatric risk of mortality (PRISM) models within the overall population as well as in specific subgroups in pediatric intensive care units (PICUs). Variants of PIM and PRISM prediction models were compared with respect to calibration (agreement be

  11. Effects of Collaborative Preteaching on Science Performance of High School Students with Specific Learning Disabilities

    Science.gov (United States)

    Thornton, Amanda; McKissick, Bethany R.; Spooner, Fred; Lo, Ya-yu; Anderson, Adrienne L.

    2015-01-01

    Investigating the effectiveness of inclusive practices in science instruction and determining how to best support high school students with specific learning disabilities (SLD) in the general education classroom is a topic of increasing research attention in the field. In this study, the researchers conducted a single-subject multiple probe across…

  12. "Life Stage-Specific" Variations in Performance in Response to Age Stereotypes

    Science.gov (United States)

    Hehman, Jessica A.; Bugental, Daphne Blunt

    2013-01-01

    In a test of life stage-specific responses to age-based stigma, older (n = 54, ages 62-92) and younger (n = 81, ages 17-22) adults were told that a task (Weschler Adult Intelligence Scale-III block design) required either (a) speed/contemporary knowledge (YA; "youth advantage") or (b) life experience/wisdom (OA; "age…

  13. Markets for Technology and the Importance of Firm-Specific Search for Innovation Performance

    DEFF Research Database (Denmark)

    Sofka, Wolfgang; Grimpe, Christoph

    , the costs of firm-specific search are only justified in underdeveloped markets. Otherwise, market transactions provide higher efficiency and flexibility. This negative cross-level interaction effect is stronger the more knowledge in an industry is covered by markets for technology. We test and support...

  14. Markets for Technology and the Importance of Firm-specific Search for Innovation Performance

    DEFF Research Database (Denmark)

    Grimpe, Christoph; Sofka, Wolfgang

    , the costs of firm-specific search are only justified in underdeveloped markets. Otherwise, market transactions provide higher efficiency and flexibility. This negative cross-level interaction effect is stronger the more knowledge in an industry is covered by markets for technology. We test and support...

  15. Infusing Culturally Responsive Instruction to Improve Mathematics Performance of Latino Students with Specific Learning Disabilities

    Science.gov (United States)

    Shumate, Lorraine; Campbell-Whatley, Gloria D.; Lo, Ya-yu

    2012-01-01

    Culturally responsive instruction has the advantage of helping diverse students make academic gains. The purpose of this study was to investigate the effects of culturally infused mathematics lessons on the academic achievement of five middle school Latino students with specific learning disabilities in a resource classroom. We used an ABACACA…

  16. Mortality and growth performance of broilers given drinking water supplemented with chicken-specific probiotics

    NARCIS (Netherlands)

    Timmerman, H.M.; Veldman, A.; Rombouts, F.M.; Beynen, A.C.

    2006-01-01

    For application in broiler production, we developed a multispecies (MSPB) and a chicken-specific (CSPB) probiotic preparation in fluid form. The MSPB contained different probiotic species of human origin, whereas the CSPB consisted of 7 Lactobacillus species isolated from the digestive tract of

  17. Mortality prediction models for pediatric intensive care : comparison of overall and subgroup specific performance

    NARCIS (Netherlands)

    Visser, Idse H. E.; Hazelzet, Jan A.; Albers, Marcel J. I. J.; Verlaat, Carin W. M.; Hogenbirk, Karin; van Woensel, Job B.; van Heerde, Marc; van Waardenburg, Dick A.; Jansen, Nicolaas J. G.; Steyerberg, Ewout W.

    2013-01-01

    To validate paediatric index of mortality (PIM) and pediatric risk of mortality (PRISM) models within the overall population as well as in specific subgroups in pediatric intensive care units (PICUs). Variants of PIM and PRISM prediction models were compared with respect to calibration (agreement be

  18. A Preliminary Investigation into the Effect of Standards-Based Grading on the Academic Performance of African-American Students

    Science.gov (United States)

    Bradbury-Bailey, Mary

    With the implementation of No Child Left Behind came a wave of educational reform intended for those working with student populations whose academic performance seemed to indicate an alienation from the educational process. Central to these reforms was the implementation of standards-based instruction and their accompanying standardized assessments; however, in one area reform seemed nonexistent---the teacher's gradebook. (Erickson, 2010, Marzano, 2006; Scriffiny, 2008). Given the link between the grading process and achievement motivation, Ames (1992) suggested the use of practices that promote mastery goal orientation. The purpose of this study was to examine the impact of standards-based grading system as a factor contributing to mastery goal orientation on the academic performance of urban African American students. To determine the degree of impact, this study first compared the course content averages and End-of-Course-Test (EOCT) scores for science classes using a traditional grading system to those using a standards-based grading system by employing an Analysis of Covariance (ANCOVA). While there was an increase in all grading areas, two showed a significant difference---the Physical Science course content average (p = 0.024) and ix the Biology EOCT scores (p = 0.0876). These gains suggest that standards-based grading can have a positive impact on the academic performance of African American students. Secondly, this study examined the correlation between the course content averages and the EOCT scores for both the traditional and standards-based grading system; for both Physical Science and Biology, there was a stronger correlation between these two scores for the standards-based grading system.

  19. Preliminary performance of the Brayton 4.25 inch radial compressor operating in a helium xenon gas mixture

    Science.gov (United States)

    Asadourian, A. S.; Hecker, T. P.; Kruchowy, R.

    1971-01-01

    Compressor performance was mapped during the Brayton cycle power system testing. The range of testing included three shaft speeds: the design speed of 36,000 rpm, 10 percent overspeed (39,600 rpm), and 10 percent underspeed (32,400 rpm). A range of compressor inlet temperatures from 60 F to 120 F and discharge pressures from 20 to 45 psia were included. The effects of turbine inlet temperatures (from 1200 F to 1600 F) on the compressor were also studied. The data presented include plots of weight flow, compressor pressure ratio, efficiency, and temperature-rise ratio.

  20. Preliminary performance appraisal of Navy V/STOL transport and search-type airplanes using hydrogen fuel

    Science.gov (United States)

    Strack, W. C.

    1974-01-01

    First-cut estimates are given of the performance advantages of liquid-hydrogen-fueled, ejector wing, V/STOL aircraft designed for shipboard delivery and search-type missions. Results indicate that the use of LH2 could reduce gross weights 30 percent, empty weights 15 percent, and energy consumption 10 percent for a fixed payload and mission. If gross weight is fixed, the delivery range could be increased about 60 percent or the hover time during a search mission doubled. No analysis or discussion of the economic and operational disadvantages is presented.

  1. Strategic Management of Business Performance Based on Innovations and Information Support in Specific Conditions of Slovakia

    Directory of Open Access Journals (Sweden)

    Rajnoha Rastislav

    2015-03-01

    Full Text Available Business performance management and measurement is a relatively complex and difficult process, which is currently undergoing significant changes in terms of both theory and practice. Previously used indicators, methods and models, largely based on financial indicators and methods of financial management, have been gradually modified and improved to provide owners and managers with a sufficient true and fair view of business performance. Despite the efforts for continuous improvement, it appears that the traditional management of enterprise performance based primarily on financial management hits its limits and companies around the world are beginning to promote new non-traditional indicators, methods and models, based primarily on non-financial, strategic and often qualitative indicators. We recommend that enterprises apply the selected methods and models of strategic business performance management in different industries of the Slovak Republic. By applying the selected strategic methods and models such as BSC, BI, strategic planning and controlling, innovations and others, a higher performance of companies can be achieved.

  2. Development of a grinding-specific performance test set-up

    DEFF Research Database (Denmark)

    Olesen, C. G.; Larsen, B. H.; Andresen, E. L.

    2015-01-01

    and an exponentially rising resistance. A custom-made grinding ergometer was developed with computer-controlled resistance and capable of collecting data during the test. The data collected can be used to find measures of grinding performance such as peak power, time to complete and the decline in repeated grinding......The aim of this study was to develop a performance test set-up for America's Cup grinders. The test set-up had to mimic the on-boat grinding activity and be capable of collecting data for analysis and evaluation of grinding performance. This study included a literature-based analysis of grinding...... demands and a test protocol developed to accommodate the necessary physiological loads. This study resulted in a test protocol consisting of 10 intervals of 20 revolutions each interspersed with active resting periods of 50 s. The 20 revolutions are a combination of both forward and backward grinding...

  3. Profiling and annotation combined method for multimedia application specific MPSoC performance estimation

    Institute of Scientific and Technical Information of China (English)

    Kai HUANG; Xiao-xu ZHANG; Si-wen XIU; Dan-dan ZHENG; Min YU; De MA; Kai HUANG; Gang CHEN; Xiao-lang YAN

    2015-01-01

    Accurate and fast performance estimation is necessary to drive design space exploration and thus support important design decisions. Current techniques are either time consuming or not accurate enough. In this paper, we solve these problems by presenting a hybrid method for multimedia multiprocessor system-on-chip (MPSoC) performance estimation. A general coverage analysis tool GNU gcov is employed to profi le the execution statistics during the native simulation. To tackle the complexity and keep the analysis and simulation manageable, the orthogonalization of communication and computation parts is adopted. The estimation result of the computation part is annotated to a transaction accurate model for further analysis, by which a gradual refi nement of MPSoC performance estimation is supported. The implementation and its experimental results prove the feasibility and efficiency of the proposed method.

  4. A Preliminary Study of Functional Brain Activation among Marijuana Users during Performance of a Virtual Water Maze Task

    Directory of Open Access Journals (Sweden)

    Jennifer Tropp Sneider

    2013-01-01

    Full Text Available Numerous studies have reported neurocognitive impairments associated with chronic marijuana use. Given that the hippocampus contains a high density of cannabinoid receptors, hippocampal-mediated cognitive functions, including visuospatial memory, may have increased vulnerability to chronic marijuana use. Thus, the current study examined brain activation during the performance of a virtual analogue of the classic Morris water maze task in 10 chronic marijuana (MJ users compared to 18 nonusing (NU comparison subjects. Imaging data were acquired using blood oxygen level-dependent (BOLD functional MRI at 3.0 Tesla during retrieval (hidden platform and motor control (visible platform conditions. While task performance on learning trials was similar between groups, MJ users demonstrated a deficit in memory retrieval. For BOLD fMRI data, NU subjects exhibited greater activation in the right parahippocampal gyrus and cingulate gyrus compared to the MJ group for the Retrieval-Motor Control contrast (NU > MJ. These findings suggest that hypoactivation in MJ users may be due to differences in the efficient utilization of neuronal resources during the retrieval of memory. Given the paucity of data on visuospatial memory function in MJ users, these findings may help elucidate the neurobiological effects of marijuana on brain activation during memory retrieval.

  5. Effect of the application of an electric field on the performance of a two-phase loop device: preliminary results

    Science.gov (United States)

    Creatini, F.; Di Marco, P.; Filippeschi, S.; Fioriti, D.; Mameli, M.

    2015-11-01

    In the last decade, the continuous development of electronics has pointed out the need for a change in mind with regard to thermal management. In the present scenario, Pulsating Heat Pipes (PHPs) are novel promising two-phase passive heat transport devices that seem to meet all present and future thermal requirements. Nevertheless, PHPs governing phenomena are quite unique and not completely understood. In particular, single closed loop PHPs manifest several drawbacks, mostly related to the reduction of device thermal performance and reliability, i.e. the occurrence of multiple operational quasi-steady states. The present research work proposes the application of an electric field as a technique to promote the circulation of the working fluid in a preferential direction and stabilize the device operation. The tested single closed loop PHP is made of a copper tube with an inner tube diameter equal to 2.00 mm and filled with pure ethanol (60% filling ratio). The electric field is generated by a couple of wire-shaped electrodes powered with DC voltage up to 20 kV and laid parallel to the longitudinal axis of the glass tube constituting the adiabatic section. Although the electric field intensity in the working fluid region is weakened both by the polarization phenomenon of the working fluid and by the interposition of the glass tube, the experimental results highlight the influence of the electric field on the device thermal performance and encourage the continuation of the research in this direction.

  6. Pilot scale biodiesel production from microbial oil of Rhodosporidium toruloides DEBB 5533 using sugarcane juice: Performance in diesel engine and preliminary economic study.

    Science.gov (United States)

    Soccol, Carlos Ricardo; Dalmas Neto, Carlos José; Soccol, Vanete Thomaz; Sydney, Eduardo Bittencourt; da Costa, Eduardo Scopel Ferreira; Medeiros, Adriane Bianchi Pedroni; Vandenberghe, Luciana Porto de Souza

    2016-10-21

    A successful pilot-scale process for biodiesel production from microbial oil (Biooil) produced by Rhodosporidium toruloides DEBB 5533 is presented. Using fed-batch strategy (1000L working volume), a lipid productivity of 0.44g/L.h was obtained using a low-cost medium composed by sugarcane juice and urea. The microbial oil was used for biodiesel production and its performance was evaluated in diesel engine tests, showing very good performance, especially for the blend B20 SCO, when operating at 2500rpm with lower pollutant emissions (CO2 - 220% less; CO - 7-fold less; NOX 50% less and no detectable HC emissions (blends of standard biofuel from soybean oil. A preliminary analysis showed that microbial biodiesel is economically competitive (US$ 0.76/L) when compared to the vegetable biodiesel (US$ 0.81/L). Besides, the yield of biodiesel from microbial oil is higher (4172L/ha of cultivated sugarcane) that represents 6.3-fold the yield of standard biodiesel (661L/ha of cultivated soybean). Copyright © 2016 Elsevier Ltd. All rights reserved.

  7. Variable interaction specificity and symbiont performance in Panamanian Trachymyrmex and Sericomyrmex fungus-growing ants

    DEFF Research Database (Denmark)

    de Fine Licht, Henrik Hjarvard; Boomsma, Jacobus Jan

    2014-01-01

    ) ants produce carbohydrate active enzymes that degrade plant material collected by the ants and offer them food in exchange. The spectrum of these enzyme activities is an important symbiont service to the host but may vary among cultivar genotypes. The sympatric occurrence of several Trachymyrmex...... and Sericomyrmex higher attine ants in Gamboa, Panama provided the opportunity to do a quantitative study of species-level interaction-specificity. Results We genotyped the ants for Cytochrome Oxidase and their Leucoagaricus fungal cultivars for ITS rDNA. Combined with activity measurements for 12 carbohydrate......Background Cooperative benefits of mutualistic interactions are affected by genetic variation among the interacting partners, which may have consequences for interaction-specificities across guilds of sympatric species with similar mutualistic life histories. The gardens of fungus-growing (attine...

  8. Performance Measurements of a Low Specific Speed TurboClaw® Compressor

    Science.gov (United States)

    Parra, J.; Cattell, R.; Etemad, S.; Pullen, K. R.

    2015-08-01

    Low specific speed compressors have been historically based on positive displacement machines. Attempts to bring advantages of turbomachinery such as oil free, low parts counts, low cost of manufacture, and reliability to low flow rate applications have not been sparse, but the principle difficulty has always been that the conventional turbomachine design operates at ultra-high speed to deliver low volume flow rates. This is synonymous with low efficiency due to higher losses (windage, surface finish, and tip clearances). The innovative TurboClaw® design is a low specific speed turbomachinery with forward swept impeller geometry. It owes its high efficiency and operational stability to careful design of its nearly tangential forward swept blading and diffuser geometry.

  9. Analytical performance specifications based on how clinicians use laboratory tests. Experiences from a post-analytical external quality assessment programme.

    Science.gov (United States)

    Thue, Geir; Sandberg, Sverre

    2015-05-01

    Analytical performance specifications can be based on three different models: the effect of analytical performance on clinical outcome, based on components of biological variation of the measurand or based on state-of-the-art. Models 1 and 3 may to some degree be combined by using case histories presented to a large number of clinicians. The Norwegian Quality Improvement of Primary Care Laboratories (Noklus) has integrated vignettes in its external quality assessment programme since 1991, focusing on typical clinical situations in primary care. Haemoglobin, erythrocyte sedimentation rate (ESR), HbA1c, glucose, u-albumin, creatinine/estimated glomerular filtration rate (eGFR), and Internationl Normalised Ratio (INR) have been evaluated focusing on critical differences in test results, i.e., a change from a previous result that will generate an "action" such as a change in treatment or follow-up of the patient. These critical differences, stated by physicians, can translate into reference change values (RCVs) and assumed analytical performance can be calculated. In general, assessments of RCVs and therefore performance specifications vary both within and between groups of doctors, but with no or minor differences regarding specialisation, age or sex of the general practitioner. In some instances state-of-the-art analytical performance could not meet clinical demands using 95% confidence, whereas clinical demands were met using 80% confidence in nearly all instances. RCVs from vignettes should probably not be used on their own as a basis for setting analytical performance specifications, since clinicians seem "uninformed" regarding important principles. They could rather be used as a background for focus groups of "informed" physicians in discussions of performance specifications tailored to "typical" clinical situations.

  10. The Context-Specific Conceptions of Learning in Case-Based Accounting Assignments, Students' Characteristics and Performance

    Science.gov (United States)

    Moilanen, Sinikka

    2017-01-01

    The present study contributes to accounting education literature by describing context-specific conceptions of learning related to case assignments, and by exploring the associations between the conceptions of learning, students' characteristics and performance. The data analysed consist of 1320 learning diaries of 336 students, connected with…

  11. No effect of partner age and lifespan on female age‐specific reproductive performance in blue tits

    NARCIS (Netherlands)

    Amininasab, Seyed Mehdi; Hammers, Martijn; Vedder, Oscar; Komdeur, Jan; Korsten, Peter

    2016-01-01

    Studies of age-specific reproductive performance are fundamental to our understanding of population dynamics and the evolution of life-history strategies. In species with bi-parental care, reproductive ageing trajectories of either parent may be influenced by their partner's age, but this has rarely

  12. Determinants of sport-specific postural control strategy and balance performance of amateur rugby players.

    Science.gov (United States)

    Chow, Gary C C; Fong, Shirley S M; Chung, Joanne W Y; Chung, Louisa M Y; Ma, Ada W W; Macfarlane, Duncan J

    2016-11-01

    Postural control strategy and balance performance of rugby players are important yet under-examined issues. This study aimed to examine the differences in balance strategy and balance performance between amateur rugby players and non-players, and to explore training- and injury-related factors that may affect rugby players' balance outcomes. Cross-sectional and exploratory study. Forty-five amateur rugby players and 41 healthy active individuals participated in the study. Balance performance and balance strategies were assessed using the sensory organization test (SOT) of the Smart Equitest computerized dynamic posturography machine. Rugby training history and injury history were solicited from the participants. The SOT strategy scores were 1.99-54.90% lower in the rugby group than in the control group (prugby group than in the control group (prugby training (in years) was independently associated with the SOT condition 6 strategy score, explaining 15.7% of its variance (p=0.006). There was no association between SOT condition 6 strategy/equilibrium scores and injury history among the rugby players (p>0.05). Amateur rugby players demonstrated inferior balance strategy and balance performance compared to their non-training counterparts. Their suboptimal balance strategy was associated with insufficient training experience but not with history of injury. Copyright © 2016 Sports Medicine Australia. Published by Elsevier Ltd. All rights reserved.

  13. Temporal specificity of training: intra-day effects on biochemical responses and Olympic-Weightlifting performances.

    Science.gov (United States)

    Ammar, Achraf; Chtourou, Hamdi; Trabelsi, Khaled; Padulo, Johnny; Turki, Mouna; El Abed, Kais; Hoekelmann, Anitta; Hakim, Ahmed

    2015-01-01

    The aim of this study was to investigate the performance of an Olympic-Weightlifting session training at three times of the day on the performance related to biochemical responses. Nine weightlifters (21 ± 0.5 years) performed, in randomised order, on three Olympic-Weightlifting training (snatch, clean and jerk) sessions (08:00 a.m., 02:00 p. m., 06:00 p. m.). Blood samples were collected: before, 3 min and 48 h after each training session. Haematological parameters and markers of muscle injury were assessed. Resting oral temperature and rating of perceived exertion (RPE) were also assessed during each session. ANOVA showed that the performance was better (P < 0.001) at 02:00 p. m. with a less RPE (P < 0.01) compared to the morning and the evening sessions while there was higher (P < 0.05) oral temperature at 06:00 p. m. versus 08:00 a.m. and 02:00 p. m. Muscle damage changed immediately (without significant effect after 48 h) after the training sessions with lower values ​​in the evening compared to the morning. In conclusion, the afternoon training is more effective than morning or evening sessions for weightlifters. Therefore, coaches and weightlifters should be advised to schedule their training session in the afternoon hour.

  14. Preliminary validation of high performance liquid chromatography method for detection of methyl-testosterone residue in carp muscle

    Science.gov (United States)

    Jiang, Jie; Lin, Hong; Fu, Xiaoting; Li, Mingming

    2005-07-01

    The use of synthetic anabolic steroid methyltestosterone (MT) as growth promoter is prohibited in China. Validations of analytical methods for MT residue in food and the results obtained have become indispensable. The high performance liquid chromatography (HPLC) method for the detection of MT with liquid-liquid extraction by trichloromethane-methanol in carp muscle tissue was preliminarily validated with reference to the following parameters: recovery (accuracy) at the 1, 5 and l0 mgkg-1 level, between-run and within-run CV values (repeatability, also called relative standard deviation (RSD)) and limit of detection. The recoveries were above 80% and the between-run and within-run CV values below 10% for muscle tissue. The limit of detection was 0.05 mgkg-1.

  15. Preliminary study on heat load using calorimetric measurement during long-pulse high-performance discharges on EAST

    Science.gov (United States)

    Liu, Y. K.; Hamada, N.; Hanada, K.; Gao, X.; Liu, H. Q.; Yu, Y. W.; Qian, J. P.; Yang, L.; Xu, T. J.; Jie, Y. X.; Yao, Y.; Wang, S. S.; Xu, J. C.; Yang, Z. D.; Li, G. S.; EAST Team

    2017-04-01

    Experimental Advanced Superconducting Tokamak (EAST) aims to demonstrate steady-state advanced high-performance H-mode plasmas with an ITER-like configuration, plasma control and heating schemes. The plasma-facing components in EAST are actively cooled, providing good conditions for researching long-pulse and high-energy discharges. A long-pulse high-performance plasma discharge (#59892 discharge) of up to 103 s with a core electron temperature of up to 4.5 keV was sustained with an injected energy exceeding 0.22 GJ in the 2015–2016 experimental campaign. A calorimetric measurement utilizing the temperature increment of cooling water is carried out to calculate the heat load on the strike point region of the lower divertor during long-pulse discharges in EAST. For the long-pulse and high-energy discharges, the comparison of the measurement results for the heat load measured by divertor Langmuir probes and the calorimetry diagnostic indicates that most of the heat load is delivered to the divertor panels as plasma, not radiation, and charge exchange neutrals. The ratio of the heat load on the strike point region of the lower divertor to the total injected energy is on average 42.5% per discharge with the lower single null divertor configuration. If the radiated energy loss measured by the fast bolometer diagnostic is taken into consideration, the ratio is found to be 61.6%. The experimental results and the analysis of the physics involved in these discharges are reported and discussed.

  16. A preliminary investigation of the biomechanical and perceptual influence of chain resistance on the performance of the snatch.

    Science.gov (United States)

    Coker, Cheryl A; Berning, Joseph M; Briggs, Doug L

    2006-11-01

    The purpose of this study was to determine whether the addition of chains to a barbell during the performance of the snatch would invoke differences in execution compared with lifting a conventional barbell without chains. Additionally, subjects were asked whether they perceived that the addition of chains had effects on their performance, and, if so, what those effects were. Four male and 3 female competitive weightlifters who regularly used chains as part of their training programs participated in the study. They were compared lifting 80% of 1 repetition maximum (1RM) using conventional barbells with 80% of 1RM, 5% of which was accounted for by chains. The same procedure was used with 85% of 1RM. Variables examined included maximum vertical displacement of the bar, maximum bar velocity, rate of force production of the bar, and vertical ground reaction forces for the first pull, unweighting, and second pull phases of the lift. Results indicated that there were no statistically significant differences between the chain vs. no-chain conditions at either 80% or 85% of 1RM. In contrast, 100% of the subjects stated that they perceived that the addition of chains made them work harder during the snatch. They suggested that the chains forced them to pull harder throughout the lift and that oscillation of the chains required their shoulders, abdominals, and back to work harder to stabilize the bar in the catch phase. Although statistical results indicate that chains have no influence on the snatch technique, chains may have a psychological impact and possibly invoke a physiological training response by increasing strength of muscles required to stabilize the bar during the catch phase if used over time.

  17. 'Timed up and go' and brain atrophy: a preliminary MRI study to assess functional mobility performance in multiple sclerosis.

    Science.gov (United States)

    Lorefice, Lorena; Coghe, G; Fenu, G; Porta, M; Pilloni, G; Frau, J; Corona, F; Sechi, V; Barracciu, M A; Marrosu, M G; Pau, M; Cocco, E

    2017-09-11

    Motor and cognitive disabilities are related to brain atrophy in multiple sclerosis (MS). 'Timed up and go' (TUG) has been recently tested in MS as functional mobility test, as it is able to evaluate ambulation/coordination-related tasks, as well as cognitive function related to mobility. The objective of this study is to evaluate the relationship between brain volumes and TUG performances. Inclusion criteria were a diagnosis of MS and the ability to walk at least 20 m. TUG was performed using a wearable inertial sensor. Times and velocities of TUG sub-phases were calculated by processing trunk acceleration data. Patients underwent to a brain MRI, and volumes of whole brain, white matter (WM), grey matter (GM), and cortical GM (C) were estimated with SIENAX. Sixty patients were enrolled. Mean age was 41.5 ± 11.6 years and mean EDSS 2.3 ± 1.2. Total TUG duration was correlated to lower WM (ρ = 0.358, p = 0.005) and GM (ρ = 0.309, p = 0.017) volumes. A stronger association with lower GM volume was observed for intermediate (ρ = 0.427, p = 0.001) and final turning (ρ = 0.390, p = 0.002). TUG is a useful tool in a clinical setting as it can not only evaluate patients' disability in terms of impaired functional mobility, but also estimate pathological features, such as grey atrophy.

  18. Performance Assessment of GPS-Sensed Precipitable Water Vapor using IGS Ultra-Rapid Orbits: A Preliminary Study in Thailand

    Directory of Open Access Journals (Sweden)

    Yoon-Soo Choi

    2011-01-01

    Full Text Available Precipitable Water Vapor (PWV is a significant variable used for climate change studies. Currently PWV can be derived from the Global Positioning System (GPS observation in addition to the specific instruments such as Radiosondes (RS, Microwave Radiometers (MWR and Meteorological Satellites. To accurately derive PWV from GPS data, long periods of observation time in conjunction with final orbit data have to be applied in the data processing steps. This final orbit data can be acquired from the International GNSS Service (IGS with 13 days latency, which is not practical in climate change studies or meteorological forecasting. Alternatively, real-time ultra-rapid orbits are more suitable for this application but with lower orbit accuracy. It is therefore interesting to evaluate the impact of using different orbits in the estimation of PWV. In this study, data from permanent GPS base stations in Thailand were processed using Bernese 5.0 software to derive near real-time PWV values. Ultra-rapid orbit data have been introduced in the data processing step with different time windows and compared to that using final orbit data with the 24-hr time window. The results have shown that 1.0 mm and 2.9 mm biases can be achieved using 24-hr and 12-hr time windows, respectively. These results therefore address the potential use of ultra-rapid orbits for a near real-time estimation of PWV.

  19. Acute Effects of Different Methods of Stretching and Specific Warm-ups on Muscle Architecture and Strength Performance.

    Science.gov (United States)

    Sá, Marcos A; Matta, Thiago T; Carneiro, Simone P; Araujo, Carolina O; Novaes, Jefferson S; Oliveira, Liliam F

    2016-08-01

    Sá, MA, Matta, TT, Carneiro, SP, Araujo, CO, Novaes, JS, and Oliveira, LF. Acute effects of different methods of stretching and specific warm-ups on muscle architecture and strength performance. J Strength Cond Res 30(8): 2324-2329, 2016-The purpose of the study was to investigate the acute effects of 2 stretching interventions, proprioceptive neuromuscular facilitation (PNF) and passive static stretching (PSS), and a specific warm-up (SW) on the strength and architecture of the vastus laterallis and biceps femoris muscles in a subsequent performance on a strength training session (STS). Musculoskeletal ultrasound images were acquired from 9 men before and immediately after stretchings or a SW, and 10 minutes after a STS. The STS consisted of the following exercises: leg extension, leg curl, leg press, and hack machine squat. The PNF resulted in lower performance for all situations. The PSS and SW improved performance for the leg press compared with the PNF and controls (CSs). For the hack machine squat, SWs resulted in higher performance than stretching conditions. The vastus lateralis muscle fascicle length (FL) increases after a STS for PNF. The biceps femoris muscle showed a higher pennation angle 10 minutes after the STS for PSS; the FL increases immediately after PSS and then decreases 10 minutes after the STS for PSS. As per our results, the SWs should be performed before STSs, whereas PNF stretching should not be prescribed because this condition impairs subsequent performance. These results may assist health professionals in prescribing resistance training.

  20. Nitrogen-doped porous carbon with an ultrahigh specific surface area for superior performance supercapacitors

    Science.gov (United States)

    Long, Chao; Zhuang, Jianle; Xiao, Yong; Zheng, Mingtao; Hu, Hang; Dong, Hanwu; Lei, Bingfu; Zhang, Haoran; Liu, Yingliang

    2016-04-01

    Owing to its abundant nitrogen content, silk cocoon is a promising precursor for the synthesis of Nitrogen-doped porous carbon (N-PC). Using a simple staged KOH activation, the prepared sample displays particular nanostructure with ultrahigh specific surface area (3841 m2 g-1) and appropriate pore size, providing favorable pathways for transportation and penetration of electrolyte ions. Additionally, the doped nitrogen atoms ensure the samples with pseudocapacitive behavior. Those special characteristics endow N-PCs with high capacity, low resistance, and long-term stability, indicating a wonderful potential for application in energy-storage devices.

  1. Variable interaction specificity and symbiont performance in Panamanian Trachymyrmex and Sericomyrmex fungus-growing ants.

    Science.gov (United States)

    De Fine Licht, Henrik H; Boomsma, Jacobus J

    2014-12-04

    Cooperative benefits of mutualistic interactions are affected by genetic variation among the interacting partners, which may have consequences for interaction-specificities across guilds of sympatric species with similar mutualistic life histories. The gardens of fungus-growing (attine) ants produce carbohydrate active enzymes that degrade plant material collected by the ants and offer them food in exchange. The spectrum of these enzyme activities is an important symbiont service to the host but may vary among cultivar genotypes. The sympatric occurrence of several Trachymyrmex and Sericomyrmex higher attine ants in Gamboa, Panama provided the opportunity to do a quantitative study of species-level interaction-specificity. We genotyped the ants for Cytochrome Oxidase and their Leucoagaricus fungal cultivars for ITS rDNA. Combined with activity measurements for 12 carbohydrate active enzymes, these data allowed us to test whether garden enzyme activity was affected by fungal strain, farming ants or combinations of the two. We detected two cryptic ant species, raising ant species number from four to six, and we show that the 38 sampled colonies reared a total of seven fungal haplotypes that were different enough to represent separate Leucoagaricus species. The Sericomyrmex species and one of the Trachymyrmex species reared the same fungal cultivar in all sampled colonies, but the remaining four Trachymyrmex species largely shared the other cultivars. Fungal enzyme activity spectra were significantly affected by both cultivar species and farming ant species, and more so for certain ant-cultivar combinations than others. However, relative changes in activity of single enzymes only depended on cultivar genotype and not on the ant species farming a cultivar. Ant cultivar symbiont-specificity varied from almost full symbiont sharing to one-to-one specialization, suggesting that trade-offs between enzyme activity spectra and life-history traits such as desiccation

  2. A Performance Evaluation for IT/IS Implementation in Organisation: Preliminary New IT/IS Capability Evaluation (NICE Model

    Directory of Open Access Journals (Sweden)

    Hafez Salleh

    2011-12-01

    Full Text Available Most of the traditional IT/IS performance measures are based on productivity and process, which mainly focus on method of investment appraisal. There is a need to produce alternative holistic measurement models that enable soft and hard issues to be measured qualitatively. A New IT/IS Capability Evaluation (NICE framework has been designed to measure the capability of organisations to'successfully implement IT systems' and it is applicable across industries.The idea is to provide managers with measurement tools to enable them to identify where improvements are required within their organisations and to indicate their readiness prior to IT investment. The NICE framework investigates four organisational key elements: IT, Environment, Process and People, and is composed of six progressive stages of maturity that a company can achieve its IT/IS capabilities. For each maturity stage, the NICE framework describes a set of critical success factors that must be in place for the company to achieve each stage.

  3. Rorschach Performance Assessment System (R-PAS) and vulnerability to stress: A preliminary study on electrodermal activity during stress.

    Science.gov (United States)

    Giromini, Luciano; Ando', Agata; Morese, Rosalba; Salatino, Adriana; Di Girolamo, Marzia; Viglione, Donald J; Zennaro, Alessandro

    2016-12-30

    This study investigated the predictive validity of the ten Rorschach Performance Assessment System (R-PAS) variables from the Stress and Distress domain, by testing whether they predicted increased sympathetic reactivity to a mild, laboratory-induced stress, occurred one week after Rorschach administration. A relatively small student sample (N=52) contributed to this research: During a first meeting (T1) participants were administered the Rorschach task according to R-PAS guidelines; about one week later (T2) their electrodermal activity (EDA) was recorded during exposure to a mild laboratory stress-inducing task. Based on literature indicating that exposure to stress tends to increase physiological vulnerability/reactivity to stressful situations, we anticipated that Stress and Distress R-PAS variables measured at T1 would positively correlate with increased sympathetic reactivity to stress at T2, as indicated by greater EDA changes from baseline to stress and recovery. Results partially confirmed our hypotheses: (a) the mean of and (b) the majority of the Stress and Distress R-PAS variables were significantly correlated, in the expected direction, with medium and medium to large effect sizes.

  4. AN APPLICATION SPECIFIC WINDOWS MANAGEMENT INSTRUMENTATION ARCHITECTURE FOR IMPROVING PERFORMANCE ON WIRELESS NETWORK

    Directory of Open Access Journals (Sweden)

    Lavanya Sankara Narayanan

    2014-01-01

    Full Text Available Wireless Communications is one of the fastest growing segments in the communications industry. Wireless Network is the network that facilitates communication among two or more computers connected through the standard network protocols, without network cabling. Generally, the Wireless Network is termed as Wireless Local Area Networks (WLAN. A WLAN is a collection of network components connected by electromagnetic (radio waves instead of cables. Each Wireless Network consists of a Network Provider, which provides the network connection to the user. With the help of this network provider, the client (user can able to transfer the data to and from the server. In this process, if the speed between the client and the server does not match, then there may be the chance for data loss. Due to the data loss, the network performance will get reduced. To avoid these problems, we propose architecture for wireless network communication, in order to reduce the data loss and other problems and to increase the network performance. The proposed architecture can able to perform on both the TCP layer and UDP layer.

  5. Performance in chemistry problem solving: A study of expert/novice strategies and specific cognitive factors

    Science.gov (United States)

    Engemann, Joseph Francis

    The purpose of this study was (a) to determine whether any relationships exist between chemistry problem-solving performance and field dependent-independent cognitive style, logical reasoning ability, mental capacity, age, gender, and/or academic level, and (b) to compare the problem-solving strategies employed by novices, advanced novices, and experts in chemistry. The Group Assessment of Logical Thinking (GALT), the Group Embedded Figures Test (GEFT), and the Figural Intersection Test (FIT) were administered to 29 freshman and junior university chemistry students and 19 Regents and Advanced Placement high school chemistry students. In addition, six mole concept problems were given to these participants, as well as to another 25 participants classified as advanced novices or experts in chemistry. All six solutions for each participant were evaluated in order to obtain a problem-solving performance score. Participants were audiotaped as they "talked aloud" during the problem-solving session. Tapes were transcribed into protocols, 37 of which were selected and analyzed for choice of problem-solving strategy and time to solution. Analyses of variance were conducted to look for significant effects of gender or academic level on field dependent-independent cognitive style, logical reasoning ability, mental capacity, and problem-solving performance. These analyses provided evidence of a significant relationship between the conservation subtest of the GALT and gender (p < .05), between the proportional reasoning subtest of the GALT and gender (p < .05), and between mental capacity and academic level (p < .01). A multiple regression analysis reported that problem-solving performance is related to an interaction between logical reasoning ability and mental capacity. A relationship between academic level and chemistry problem-solving performance was also reported. From an analysis of verbal protocols of successful problem solvers at all three levels of experience, the

  6. Current Status of the Transmutation Reactor Technology and Preliminary Evaluation of Transmutation Performance of the KALIMER Core

    Energy Technology Data Exchange (ETDEWEB)

    Hong, Ser Gi; Sim, Yoon Sub; Kim, Yeong Il; Kim, Young Gyum; Lee, Byung Woon; Song, Hoon; Lee, Ki Bog; Jang, Jin Wook; Lee, Dong Uk

    2005-08-15

    devised. It has been considered that the degradations of core performances resulting from increase of the transmutation rate are very important problems. From the analysis results of the state-of-art of the nuclear transmutation technology, the following technical research topics are determined as the technical solution ways for the future development and enhancement of the transmutation technology; 1) the improvement of core safety through the reduction of the coolant void reactivity worth by using the void duct assembly, 2) the design of a reference transmutation reactor for the future transmutation research through the change of the KALIMER-600 reactor core into the transmutation reactor and its core performance analysis, 3) the optimization study of the hybrid loading of uranium-free fuel and uranium fuel to improve the transmutation rate and the core safety parameters. Finally, the feasibility of the transmutation core suggested above where the void duct assemblies are devised to improve the sodium void reactivity worth and to achieve the power flattening under a single fuel enrichment and a single type of fuel assembly is analyzed and assessed. The results show that this core has its sodium coolant void reactivity less than 3$ and this core can transmutate the TRU nuclides discharged from two LWRs of the same thermal power.

  7. Feasibility of developing a portable driver performance data acquisition system for human factors research: Design specifications. Volume 3

    Energy Technology Data Exchange (ETDEWEB)

    Carter, R.J.; Barickman, F.S.

    1998-01-01

    A two-phase, multi-year research program entitled ``development of a portable driver performance data acquisition system for human factors research was recently completed. The primary objective of the project was to develop a portable data acquisition system for crash avoidance research (DASCAR) that will allow driver performance data to be collected using a large variety of vehicle types and that would be capable of being installed on a given vehicle type within a relatively short-time frame. During Phase 1 a feasibility study for designing and fabricating DASCAR was conducted. In phase 2 of the research DASCAR was actually developed and validated. This technical memorandum documents the results from the feasibility study. It is subdivided into three volumes. Volume one addresses the last five items in the phase 1 research and the first issue in the second phase of the project. Volume 2 presents the related appendices. Volume three (this report) displays the design specifications developed for DASCAR during the ``develop design requirements and specifications for a portable driver performance data acquisition system`` task. Design specifications were assembled for each DASCAR element. The specifications were prepared in sufficient detail to allow a third party to use them to design, develop, procure, and subsequently construct the data acquisition system. This report also covers the background to the program.

  8. Mortality and growth performance of broilers given drinking water supplemented with chicken-specific probiotics.

    Science.gov (United States)

    Timmerman, H M; Veldman, A; van den Elsen, E; Rombouts, F M; Beynen, A C

    2006-08-01

    For application in broiler production, we developed a multispecies (MSPB) and a chicken-specific (CSPB) probiotic preparation in fluid form. The MSPB contained different probiotic species of human origin, whereas the CSPB consisted of 7 Lactobacillus species isolated from the digestive tract of chickens. In a field trial with broilers, MSPB treatment resulted in a slight increase (by 1.84%) in broiler productivity based on an index taking into account daily weight gain, feed efficiency, and mortality. The CSPB treatment reduced mortality in 2 subsequent field trials and raised productivity by 2.94 and 8.70%. In a controlled trial with broilers showing a high index of productivity, probiotic treatment further raised productivity by 3.72%. Based on the present 4 studies in combination with 9 studies published earlier, it is suggested that with higher productivity rates of the broilers the effect of probiotics becomes smaller.

  9. Superovulation at a specific stage of the estrous cycle determines the reproductive performance in mice.

    Science.gov (United States)

    Inyawilert, Wilasinee; Liao, Yu-Jing; Tang, Pin-Chi

    2016-12-01

    Inconsistent reproductive performance has been reported in superovulated mice. Hence, the aim of this study was to analyze the effect and possible mechanism of superovulation timing on mouse reproductive performance. The results showed that mice superovulated at the metestrous (23.08±6.08%) and diestrous stages (33.33±11.45%) presented significantly lower pregnancy rates compared with those superovulated at the estrous stage (66.67±9.20%). After superovulation at the proestrous and estrous stages, mucin 1 (MUC1) and let-7a/let-7b microRNA (miRNA) expression levels were significantly attenuated and enhanced on embryonic day 3.5 (E3.5), respectively, whereas no significant differences in the expression level were found in mice superovulated at the other two stages. A higher number of developing and Graafian follicles was observed in the ovarian sections 48h after the administration of pregnant mare serum gonadotropin (PMSG) at the proestrous and estrous stages. The sections from mice treated at the metestrous and diestrous stages, however, presented more corpora lutea. Therefore, mice superovulated at the proestrous and estrous stages exhibited the best pregnancy rates. Furthermore, the disordered expression of MUC1 and let-7a/let-7b miRNA in mice superovulated at the metestrous and diestrous stages may impair reproduction performance. Copyright © 2016 Society for Biology of Reproduction & the Institute of Animal Reproduction and Food Research of Polish Academy of Sciences in Olsztyn. Published by Elsevier Urban & Partner Sp. z o.o. All rights reserved.

  10. High Performance Computing - Power Application Programming Interface Specification Version 2.0.

    Energy Technology Data Exchange (ETDEWEB)

    Laros, James H. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Grant, Ryan [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Levenhagen, Michael J. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Olivier, Stephen Lecler [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Pedretti, Kevin [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Ward, H. Lee [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Younge, Andrew J. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2017-03-01

    Measuring and controlling the power and energy consumption of high performance computing systems by various components in the software stack is an active research area. Implementations in lower level software layers are beginning to emerge in some production systems, which is very welcome. To be most effective, a portable interface to measurement and control features would significantly facilitate participation by all levels of the software stack. We present a proposal for a standard power Application Programming Interface (API) that endeavors to cover the entire software space, from generic hardware interfaces to the input from the computer facility manager.

  11. General guidelines about performance specifications for purchasing equipment for x-ray diagnostics, with comments

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-12-01

    These general guidelines are intended to be used as a basis for what requirements are reasonable from a radiation protection point of view and should be part of the contract in connection with the purchase of equipment for x-ray diagnostics. Technical performance requirements are addressed as well as items like documentation, instructions for use and education and training. The guidelines are also useful for the design of quality assurance programs. In the comments in addition to these guidelines legal aspects are noted, including a list of relevant laws, regulations and directives. Standards, both national and international, within the field are referred to with a short description of their content. 40 refs.

  12. Evaluation of a broadband textile monopole antenna performance for subject-specific on-body applications

    Science.gov (United States)

    Rahim, H. A.; Abdulmalek, M.; Soh, P. J.; Vandenbosch, G. A. E.

    2017-01-01

    The human body characteristics with different dimensions and tissue properties are one of the major factors in influencing the on-body radio propagation channel characteristics. A broadband textile monopole antenna operating at 2.45 GHz is evaluated to validate its performance on different subjects' characteristics. The results show that the textile monopole antenna is sufficiently robust against the variations introduced by the body up to 0.9 and 0.2% changes in the antenna's impedance matching level and resonant frequency shift when evaluated 10 mm from the body.

  13. Assessment of myocardial elastography performance in phantoms under combined physiologic motion configurations with preliminary in vivo feasibility

    Science.gov (United States)

    Okrasinski, S. J.; Ramachandran, B.; Konofagou, E. E.

    2012-09-01

    Myocardial elastography (ME) is a non-invasive, ultrasound-based strain imaging technique, which can detect and localize abnormalities in myocardial function. By acquiring radio-frequency (RF) frames at high frame rates, the deformation of the myocardium can be estimated, and used to identify regions of abnormal deformation indicative of cardiovascular disease. In this study, the primary objective is to evaluate the effect of torsion on the performance of ME, while the secondary objective is to image inclusions during different motion schemes. Finally, the phantom findings are validated with an in vivo human case. Phantoms of homogeneous stiffness, or containing harder inclusions, were fixed to a pump and motors, and imaged. Incremental displacements were estimated from the RF signals, and accumulated over a motion cycle, and rotation angle, radial strain and circumferential strain were estimated. Phantoms were subjected to four motion schemes: rotation, torsion, deformation, and a combination of torsion and deformation. Sonomicrometry was used as a gold standard during deformation and combined motion schemes. In the rotation scheme, the input and estimated rotation angle agree in both the homogeneous and inclusion phantoms. In the torsion scheme, the estimated rotation angle was found to be highest, closest to the source of torsion and lowest farthest from the source of torsion. In the deformation scheme, if an inclusion was not present, the estimated strain patterns accurately depicted homogeneity, while if an inclusion was present, abnormalities were observed which enabled detection of the inclusion. In addition, no significant rotation was detected. In the combined scheme, if an inclusion was not present, the estimated strain patterns accurately depicted homogeneity, while, if an inclusion was present, abnormalities were observed which enabled detection of the inclusion. Also, torsion was separated from the combined scheme and was found to be similar to the

  14. Acoustic and non-acoustic factors in modeling listener-specific performance of sagittal-plane sound localization

    Directory of Open Access Journals (Sweden)

    Piotr eMajdak

    2014-04-01

    Full Text Available The ability of sound-source localization in sagittal planes (along the top-down and front-back dimension varies considerably across listeners. The directional acoustic spectral features, described by head-related transfer functions (HRTFs, also vary considerably across listeners, a consequence of the listener-specific shape of the ears. It is not clear whether the differences in localization ability result from differences in the encoding of directional information provided by the HRTFs, i.e., acoustic factors, or from differences in auditory processing of those cues (e.g., spectral-shape sensitivity, i.e., non-acoustic factors.We addressed this issue by analyzing the listener-specific localization ability in terms of localization performance. Directional responses to spatially distributed broadband stimuli from 18 listeners were used. A model of sagittal-plane localization was fit individually for each listener by considering the actual localization performance, the listener-specific HRTFs representing the acoustic factor, and an uncertainty parameter representing the non-acoustic factors. The model was configured to simulate the condition of complete calibration of the listener to the tested HRTFs. Listener-specifically calibrated model predictions yielded correlations of, on average, 0.93 with the actual localization performance. Then, the model parameters representing the acoustic and non-acoustic factors were systematically permuted across the listener group.While the permutation of HRTFs affected the localization performance, the permutation of listener-specific uncertainty had a substantially larger impact. Our findings suggest that across-listener variability in sagittal-plane localization ability is only marginally determined by the acoustic factor, i.e., the quality of directional cues found in typical human HRTFs. Rather, the non-acoustic factor, supposed to represent the listeners' efficiency in processing directional cues, appears

  15. Creatine supplementation with specific view to exercise/sports performance: an update

    Directory of Open Access Journals (Sweden)

    Cooper Robert

    2012-07-01

    Full Text Available Abstract Creatine is one of the most popular and widely researched natural supplements. The majority of studies have focused on the effects of creatine monohydrate on performance and health; however, many other forms of creatine exist and are commercially available in the sports nutrition/supplement market. Regardless of the form, supplementation with creatine has regularly shown to increase strength, fat free mass, and muscle morphology with concurrent heavy resistance training more than resistance training alone. Creatine may be of benefit in other modes of exercise such as high-intensity sprints or endurance training. However, it appears that the effects of creatine diminish as the length of time spent exercising increases. Even though not all individuals respond similarly to creatine supplementation, it is generally accepted that its supplementation increases creatine storage and promotes a faster regeneration of adenosine triphosphate between high intensity exercises. These improved outcomes will increase performance and promote greater training adaptations. More recent research suggests that creatine supplementation in amounts of 0.1 g/kg of body weight combined with resistance training improves training adaptations at a cellular and sub-cellular level. Finally, although presently ingesting creatine as an oral supplement is considered safe and ethical, the perception of safety cannot be guaranteed, especially when administered for long period of time to different populations (athletes, sedentary, patient, active, young or elderly.

  16. Diagnostic tests for influenza and other respiratory viruses: determining performance specifications based on clinical setting.

    Science.gov (United States)

    Takahashi, Hiroshi; Otsuka, Yoshihito; Patterson, Bruce K

    2010-06-01

    The lack of sensitivity of rapid immunoassays in detecting the novel 2009 H1N1 influenza virus infection has led to recommendations on influenza diagnostic testing for clinicians treating patients as well as advising clinicians on testing decisions. Studies have also shown that rapid immunoassays for seasonal influenza virus show considerable variability in performance characteristics, based on age of patient, prevalence of disease, course of infection, and the quality of the kit used. While public health authorities are currently focused on influenza virus diagnostics, a lack of sensitivity of rapid immunoassays for other viral respiratory pathogens has been widely reported, such as the very limited value of rapid immunoassays for the detection of respiratory syncytial virus in adults. In light of the lack of sensitivity of diagnostic tests for suspected 2009 H1N1 influenza virus infection, as well as their variable performance characteristics for seasonal influenza virus, a number of recommendations have been made by public health authorities advising clinicians on the need for clinical judgment as an important part of testing and treatment decisions as well as reliance on local epidemiologic and surveillance data. With the availability of new molecular methodologies that are user-friendly and allow the front-line physician as well as hospital infection control programs to significantly improve respiratory viral diagnostics, there is a need to carefully determine the most optimal diagnostic testing methodology based on the clinical setting. This review will describe the historical, current, and changing dynamics of respiratory virus infection diagnostics.

  17. Preliminary performance of image quality for a low-dose C-arm CT system with a flat-panel detector

    Energy Technology Data Exchange (ETDEWEB)

    Kyung Cha, Bo [Advanced Medical Device Research Center, Korea Electrotechnology Research Institute, Ansan (Korea, Republic of); Seo, Chang-Woo [Department of Radiation Convergence Engineering, College of Health Science, Yonsei University, Wonju (Korea, Republic of); Yang, Keedong [Advanced Medical Device Research Center, Korea Electrotechnology Research Institute, Ansan (Korea, Republic of); Jeon, Seongchae, E-mail: sarim@keri.re.kr [Advanced Medical Device Research Center, Korea Electrotechnology Research Institute, Ansan (Korea, Republic of); Huh, Young [Advanced Medical Device Research Center, Korea Electrotechnology Research Institute, Ansan (Korea, Republic of)

    2015-06-01

    Digital flat panel imager (FPI)-based cone-beam computed tomography (CBCT) has been widely used in C-arm imaging for spine surgery and interventional procedures. The system provides real-time fluoroscopy with high spatial resolution and three-dimensional (3D) visualization of anatomical structure without the need for patient transportation in interventional suite. In this work, a prototype CBCT imaging platform with continuous single rotation about the gantry was developed by using a large-area flat-panel detector with amorphous Si-based thin film transistor matrix. The different 2D projection images were acquired during constant gantry velocity for reconstructed images at a tube voltage of 80–120 kVp, and different current (10–50 mA) conditions. Various scan protocols were applied to a chest phantom human by changing the number of projection images and scanning angles. The projections were then reconstructed into a volumetric data of sections by using a 3D reconstruction algorithm (e.g., filtered back projection). The preliminary quantitative X-ray performance of our CBCT system was investigated by using the American Association of Physicists in Medicine CT phantom in terms of spatial resolution, contrast resolution, and CT number linearity for mobile or fixed C-arm based CBCT application with limited rotational geometry. The novel results of the projection data with different scanning angles and angular increments in the orbital gantry platform were acquired and evaluated experimentally.

  18. Performance of a plasma window for a high pressure differentially pumped deuterium gas target for mono-energetic fast neutron production - Preliminary results

    Energy Technology Data Exchange (ETDEWEB)

    Beer, A. de; Hershcovitch, A.; Franklyn, C.B.; Straaten, S. van; Guzek, J. E-mail: jguzek@debeers.co.za

    2000-09-01

    The reactions D(d,n){sup 3}He and T(d,n){sup 4}He are frequently used for production of the mono-energetic or quasi mono-energetic neutron beams but successful applications are often limited by the intensity of the generated neutron beams. The development of a suitable neutron source for such applications as studies of resonance phenomena, fast neutron radiography, selective fast neutron activation, explosives and contraband detection and others, depends on the output ion current of the accelerator and the design of the target system. A practical solution for a high pressure gas target was previously developed and successfully implemented at De Beers Diamond Research Laboratory in Johannesburg (Guzek et al., 1999), but it is limited to applications using low (<20%) duty cycle accelerators. The concept of a plasma window for the separation of a high pressure gas target region and accelerator vacuum, that was originally developed by Hershcovitch (1995) for electron welding applications, may be suitable for operation with continuous wave accelerators at high particle current output. Preliminary test results, which have been performed with various gases (argon, helium and deuterium), indicate that implementation of the plasma window into a gas target system, for the production of intense mono-energetic fast neutron beams will be achievable.

  19. Preliminary performance of image quality for a low-dose C-arm CT system with a flat-panel detector

    Science.gov (United States)

    Kyung Cha, Bo; Seo, Chang-Woo; Yang, Keedong; Jeon, Seongchae; Huh, Young

    2015-06-01

    Digital flat panel imager (FPI)-based cone-beam computed tomography (CBCT) has been widely used in C-arm imaging for spine surgery and interventional procedures. The system provides real-time fluoroscopy with high spatial resolution and three-dimensional (3D) visualization of anatomical structure without the need for patient transportation in interventional suite. In this work, a prototype CBCT imaging platform with continuous single rotation about the gantry was developed by using a large-area flat-panel detector with amorphous Si-based thin film transistor matrix. The different 2D projection images were acquired during constant gantry velocity for reconstructed images at a tube voltage of 80-120 kVp, and different current (10-50 mA) conditions. Various scan protocols were applied to a chest phantom human by changing the number of projection images and scanning angles. The projections were then reconstructed into a volumetric data of sections by using a 3D reconstruction algorithm (e.g., filtered back projection). The preliminary quantitative X-ray performance of our CBCT system was investigated by using the American Association of Physicists in Medicine CT phantom in terms of spatial resolution, contrast resolution, and CT number linearity for mobile or fixed C-arm based CBCT application with limited rotational geometry. The novel results of the projection data with different scanning angles and angular increments in the orbital gantry platform were acquired and evaluated experimentally.

  20. High Performance Computing - Power Application Programming Interface Specification Version 1.4

    Energy Technology Data Exchange (ETDEWEB)

    Laros III, James H. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); DeBonis, David [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Grant, Ryan [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Kelly, Suzanne M. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Levenhagen, Michael J. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Olivier, Stephen Lecler [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Pedretti, Kevin [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2016-10-01

    Measuring and controlling the power and energy consumption of high performance computing systems by various components in the software stack is an active research area [13, 3, 5, 10, 4, 21, 19, 16, 7, 17, 20, 18, 11, 1, 6, 14, 12]. Implementations in lower level software layers are beginning to emerge in some production systems, which is very welcome. To be most effective, a portable interface to measurement and control features would significantly facilitate participation by all levels of the software stack. We present a proposal for a standard power Application Programming Interface (API) that endeavors to cover the entire software space, from generic hardware interfaces to the input from the computer facility manager.

  1. Mechanical design and performance specifications of anthropomorphic prosthetic hands: A review

    Directory of Open Access Journals (Sweden)

    Joseph T. Belter, MS, BS

    2013-08-01

    Full Text Available In this article, we set forth a detailed analysis of the mechanical characteristics of anthropomorphic prosthetic hands. We report on an empirical study concerning the performance of several commercially available myoelectric prosthetic hands, including the Vincent, iLimb, iLimb Pulse, Bebionic, Bebionic v2, and Michelangelo hands. We investigated the finger design and kinematics, mechanical joint coupling, and actuation methods of these commercial prosthetic hands. The empirical findings are supplemented with a compilation of published data on both commercial and prototype research prosthetic hands. We discuss numerous mechanical design parameters by referencing examples in the literature. Crucial design trade-offs are highlighted, including number of actuators and hand complexity, hand weight, and grasp force. Finally, we offer a set of rules of thumb regarding the mechanical design of anthropomorphic prosthetic hands.

  2. The antisaccade task performance deficit and specific CNV abnormalities in patients with stereotyped paraphilia and schizophrenia.

    Science.gov (United States)

    Kirenskaya, Anna V; Kamenskov, Maxim Y; Myamlin, Vadim V; Novototsky-Vlasov, Vladimir Y; Tkachenko, Andrey A

    2013-09-01

    Antisaccade task performance and mean amplitudes of slow cortical potentials (contingent negative variation--CNV) were investigated in 19 healthy volunteers, 16 schizophrenic patients (SP), and 12 patients with stereotyped form of paraphilia (PP). Compared with healthy subjects, schizophrenic and paraphilic patients committed significantly more erroneous saccades. The clear between-group CNV differences were observed during the early CNV stage that is associated with cognitive aspects of preparatory set. In SP, as compared to controls, the significant decline of CNV amplitude was found at frontal-central area. PP have demonstrated the lack of CNV over central and parietal regions, but their CNV amplitudes in frontal area did not differ from values of control group. Thus, two distinct types of CNV abnormalities have been found. The SP results have been interpreted as support for frontal dysfunction in schizophrenia. The disconnection between prefrontal cortex, sensorimotor cortex, and related subcortical structures is hypothesized in paraphilia group. © 2013 American Academy of Forensic Sciences.

  3. Mechanical design and performance specifications of anthropomorphic prosthetic hands: a review.

    Science.gov (United States)

    Belter, Joseph T; Segil, Jacob L; Dollar, Aaron M; Weir, Richard F

    2013-01-01

    In this article, we set forth a detailed analysis of the mechanical characteristics of anthropomorphic prosthetic hands. We report on an empirical study concerning the performance of several commercially available myoelectric prosthetic hands, including the Vincent, iLimb, iLimb Pulse, Bebionic, Bebionic v2, and Michelangelo hands. We investigated the finger design and kinematics, mechanical joint coupling, and actuation methods of these commercial prosthetic hands. The empirical findings are supplemented with a compilation of published data on both commercial and prototype research prosthetic hands. We discuss numerous mechanical design parameters by referencing examples in the literature. Crucial design trade-offs are highlighted, including number of actuators and hand complexity, hand weight, and grasp force. Finally, we offer a set of rules of thumb regarding the mechanical design of anthropomorphic prosthetic hands.

  4. Robotic Observatory System Design-Specification Considerations for Achieving Long-Term Sustainable Precision Performance

    Science.gov (United States)

    Wray, J. D.

    2003-05-01

    The robotic observatory telescope must point precisely on the target object, and then track autonomously to a fraction of the FWHM of the system PSF for durations of ten to twenty minutes or more. It must retain this precision while continuing to function at rates approaching thousands of observations per night for all its years of useful life. These stringent requirements raise new challenges unique to robotic telescope systems design. Critical design considerations are driven by the applicability of the above requirements to all systems of the robotic observatory, including telescope and instrument systems, telescope-dome enclosure systems, combined electrical and electronics systems, environmental (e.g. seeing) control systems and integrated computer control software systems. Traditional telescope design considerations include the effects of differential thermal strain, elastic flexure, plastic flexure and slack or backlash with respect to focal stability, optical alignment and angular pointing and tracking precision. Robotic observatory design must holistically encapsulate these traditional considerations within the overall objective of maximized long-term sustainable precision performance. This overall objective is accomplished through combining appropriate mechanical and dynamical system characteristics with a full-time real-time telescope mount model feedback computer control system. Important design considerations include: identifying and reducing quasi-zero-backlash; increasing size to increase precision; directly encoding axis shaft rotation; pointing and tracking operation via real-time feedback between precision mount model and axis mounted encoders; use of monolithic construction whenever appropriate for sustainable mechanical integrity; accelerating dome motion to eliminate repetitive shock; ducting internal telescope air to outside dome; and the principal design criteria: maximizing elastic repeatability while minimizing slack, plastic deformation

  5. Evaluating Quantum Dot Performance in Homogeneous FRET Immunoassays for Prostate Specific Antigen

    Directory of Open Access Journals (Sweden)

    Shashi Bhuckory

    2016-02-01

    Full Text Available The integration of semiconductor quantum dots (QDs into homogeneous Förster resonance energy transfer (FRET immunoassay kits for clinical diagnostics can provide significant advantages concerning multiplexing and sensitivity. Here we present a facile and functional QD-antibody conjugation method using three commercially available QDs with different photoluminescence (PL maxima (605 nm, 655 nm, and 705 nm. The QD-antibody conjugates were successfully applied for FRET immunoassays against prostate specific antigen (PSA in 50 µL serum samples using Lumi4-Tb (Tb antibody conjugates as FRET donors and time-gated PL detection on a KRYPTOR clinical plate reader. Förster distance and Tb donor background PL were directly related to the analytical sensitivity for PSA, ...which resulted in the lowest limits of detection for Tb-QD705 (2 ng/mL, followed by Tb-QD655 (4 ng/mL, and Tb-QD605 (23 ng/mL. Duplexed PSA detection using the Tb-QD655 and Tb-QD705 FRET-pairs demonstrated the multiplexing ability of our immunoassays. Our results show that FRET based on QD acceptors is suitable for multiplexed and sensitive biomarker detection in clinical diagnostics.

  6. Tactile thresholds are preserved yet complex sensory function is impaired over the lumbar spine of chronic non-specific low back pain patients. A preliminary investigation

    OpenAIRE

    Wand, BM; Di Pietro, FS; George, PJ; O'Connell, NE

    2010-01-01

    Objectives: To investigate impairments in sensory function in chronic non-specific low back pain patients and the relationship between any impairment and the clinical features of the condition. Design: A cross-sectional case-control study. Setting: Laboratory based study. Participants: Nineteen chronic non-specific low back pain patients and nineteen healthy controls. Main Outcome measures: Tactile threshold, two point discrimination distance and accuracy at a task involving recognizing lett...

  7. Performances on a cognitive theory of mind task: specific decline or general cognitive deficits? Evidence from normal aging.

    Science.gov (United States)

    Fliss, Rafika; Lemerre, Marion; Mollard, Audrey

    2016-06-01

    Compromised theory of mind (ToM) can be explained either by a failure to implement specific representational capacities (mental state representations) or by more general executive selection demands. In older adult populations, evidence supporting affected executive functioning and cognitive ToM in normal aging are reported. However, links between these two functions remain unclear. In the present paper, we address these shortcomings by using a specific task of ToM and classical executive tasks. We studied, using an original cognitive ToM task, the effect of age on ToM performances, in link with the progressive executive decline. 96 elderly participants were recruited. They were asked to perform a cognitive ToM task, and 5 executive tests (Stroop test and Hayling Sentence Completion Test to appreciate inhibitory process, Trail Making Test and Verbal Fluency for shifting assessment and backward span dedicated to estimate working memory capacity). The results show changes in cognitive ToM performance according to executive demands. Correlational studies indicate a significant relationship between ToM performance and the selected executive measures. Regression analyzes demonstrates that level of vocabulary and age as the best predictors of ToM performance. The results are consistent with the hypothesis that ToM deficits are related to age-related domain-general decline rather than as to a breakdown in specialized representational system. The implications of these findings for the nature of social cognition tests in normal aging are also discussed.

  8. Effects of Periodic Task-Specific Test Feedback on Physical Performance in Older Adults Undertaking Band-Based Resistance Exercise

    Directory of Open Access Journals (Sweden)

    Ryuichi Hasegawa

    2014-01-01

    Full Text Available The purpose of this study was to determine the effects of periodic task-specific test feedback on performance improvement in older adults undertaking community- and home-based resistance exercises (CHBRE. Fifty-two older adults (65–83 years were assigned to a muscular perfsormance feedback group (MPG, n=32 or a functional mobility feedback group (FMG, n=20. Both groups received exactly the same 9-week CHBRE program comprising one community-based and two home-based sessions per week. Muscle performance included arm curls and chair stands in 30 seconds, while functional mobility was determined by the timed up and go (TUG test. MPG received fortnightly test feedback only on muscle performance and FMG received feedback only on the TUG. Following training, there was a significant (P<0.05 interaction for all performance tests with MPG improving more for the arm curls (MPG 31.4%, FMG 15.9% and chair stands (MPG 33.7%, FMG 24.9% while FMG improved more for the TUG (MPG-3.5%, FMG-9.7%. Results from this nonrandomized study suggest that periodic test feedback during resistance training may enhance task-specific physical performance in older persons, thereby augmenting reserve capacity or potentially reducing the time required to recover functional abilities.

  9. The effect of badminton-specific exercise on badminton short-serve performance in competition and practice climates.

    Science.gov (United States)

    Duncan, Michael J; Chan, Cheryl K Y; Clarke, Neil D; Cox, Martin; Smith, Mike

    2017-03-01

    This study examined the effects of changes in physiological and psychological arousal on badminton short-serve performance in competitive and practice climates. Twenty competitive badminton players (10 males and 10 females) volunteered to participate in the study following ethics approval. After familiarisation, badminton short-serve performance was measured at rest, mid-way through and at the end of a badminton-specific exercise protocol in two conditions; competition vs. practice. Ratings of cognitive and somatic anxiety were assessed at three time points prior to badminton short-serve performance using the Mental Readiness Form 3. Heart rate and rating of perceived exertion (RPE) were assessed during the exercise protocol. Results indicated that better short-serve performance was evident in practice compared to competition (P = .034). RPE values were significantly higher in the competition condition compared to practice (P = .007). Cognitive anxiety intensity was significantly lower post-exercise in the practice condition compared to competition (P = .001). Cognitive anxiety direction showed greater debilitation post-exercise in the competition condition compared to practice (P = .01). Somatic anxiety intensity increased from pre-, to mid- to post-exercise (P = .001) irrespective of condition. This study suggests that badminton serve performance is negatively affected when physiological arousal, via badminton-specific exercise, and cognitive anxiety, via perceived competition, are high.

  10. A clinical assessment of cochlear implant recipient performance: implications for individualized map settings in specific environments.

    Science.gov (United States)

    Hey, Matthias; Hocke, Thomas; Mauger, Stefan; Müller-Deile, Joachim

    2016-11-01

    Individual speech intelligibility was measured in quiet and noise for cochlear Implant recipients upgrading from the Freedom to the CP900 series sound processor. The postlingually deafened participants (n = 23) used either Nucleus CI24RE or CI512 cochlear implant, and currently wore a Freedom sound processor. A significant group mean improvement in speech intelligibility was found in quiet (Freiburg monosyllabic words at 50 dBSPL) and in noise (adaptive Oldenburger sentences in noise) for the two CP900 series SmartSound programs compared to the Freedom program. Further analysis was carried out on individual's speech intelligibility outcomes in quiet and in noise. Results showed a significant improvement or decrement for some recipients when upgrading to the new programs. To further increase speech intelligibility outcomes when upgrading, an enhanced upgrade procedure is proposed that includes additional testing with different signal-processing schemes. Implications of this research are that future automated scene analysis and switching technologies could provide additional performance improvements by introducing individualized scene-dependent settings.

  11. Development and validation of a specific stability indicating high performance liquid chromatographic method for rizatriptan benzoate.

    Science.gov (United States)

    Mallikarjuna Rao, B; Sangaraju, Sivaiah; Srinivasu, M K; Madhavan, P; Lalitha Devi, M; Rajendra Kumar, P; Chandrasekhar, K B; Arpitha, Ch; Satya Balaji, T

    2006-06-16

    A gradient, reversed-phase liquid chromatographic (RP-LC) method was developed for the quantitative determination of rizatriptan benzoate, used to treat relieves migraine headache symptoms. The developed method can be also employed for the related substance determination in bulk samples. Forced degradation studies were performed on bulk sample of rizatriptan benzoate using acid (0.5 N hydrochloric acid), base (0.1 N sodium hydroxide), oxidation (3.0% hydrogen peroxide), water hydrolysis, heat (60 degrees C) and photolytic degradation. Mild degradation of the drug substance was observed in base hydrolysis and considerable degradation observed during oxidative stress. The chromatographic method was fine tuned using the samples generated from forced degradation studies. Good resolution between the peaks corresponds to degradation products and the analyte was achieved on Agilent Zorbax SB-CN (250 mm x 4.6 mm, 5 microm) column. The mobile phase consists of a mixture of aqueous potassium di hydrogen ortho phosphate (pH 3.4), acetonitrile and methanol. The stress sample solutions were assayed against the qualified reference standard of rizatriptan benzoate and the mass balance in each case was close to 99.7% indicating that the developed method is stability indicating. Validation of the developed method was carried out as per ICH requirements.

  12. Age- and gender-specific effects on VDR gene polymorphisms and risk of the development of multiple sclerosis in Tunisians: a preliminary study.

    Science.gov (United States)

    Ben-Selma, W; Ben-Fredj, N; Chebel, S; Frih-Ayed, M; Aouni, M; Boukadida, J

    2015-06-01

    The vitamin D receptor (VDR) polymorphisms have been reported to be associated with multiple sclerosis (MS); however, evidence remains conflicting. In this report, we investigated the association between two single nucleotide polymorphisms (SNPs) TaqI and ApaI of VDR gene and risk development of MS. TaqI and ApaI SNPs were detected by PCR-RFLP from the DNA of 60 Tunisian patients with MS and 114 healthy controls. Our results show a significant difference of the allelic frequency distribution between the case and control groups for TaqI SNP (P = 0.01), but genotype frequencies were not significantly different (P = 0.07 and 0.23). When adjusting frequency distribution of different alleles and genotypes by age, we found that the difference between the T allele frequencies of this SNP in the group of patients age [15-24] in comparison with the control group of the same age group was statistically significant (P = 0.026). Moreover, frequency of the T allele was significantly higher in male patients compared with controls of the same sex (P = 0.017). However, neither the genotype nor the allele frequency distribution was significantly different between the MS and control populations for the ApaI SNP. Our preliminary results indicate that VDR gene polymorphism could be associated with susceptibility to MS. The role of VDR gene polymorphism should be further studied in other large populations, and the distribution of other polymorphism, such as FokI and BsmI, should be also analysed to confirm another susceptibility polymorphisms gene for MS and to obtain more adequate strategies for treatment of MS.

  13. Chlorine-Induced In Situ Regulation to Synthesize Graphene Frameworks with Large Specific Area for Excellent Supercapacitor Performance.

    Science.gov (United States)

    Zhu, Yanyan; Cui, Huijuan; Meng, Xin; Zheng, Jianfeng; Yang, Pengju; Li, Li; Wang, Zhijian; Jia, Suping; Zhu, Zhenping

    2016-03-01

    Three-dimensional (3D) graphene frameworks are usually limited by a complicated preparation process and a low specific surface area. This paper presents a facile suitable approach to effectively synthesize 3D graphene frameworks (GFs) with large specific surface area (up to 1018 m(2) g(-1)) through quick thermal decomposition from sodium chloroacetate, which are considerably larger than those of sodium acetate reported in our recent study. The chlorine element in sodium chloroacetate may possess a strong capability to induce in situ activation and regulate graphene formation during pyrolysis in one step. These GFs can be applied as excellent electrode materials for supercapacitors and can achieve an enhanced supercapacitor performance with a specific capacitance of 266 F g(-1) at a current density of 0.5 A g(-1).

  14. The effects of tournament preparation on anthropometric and sport-specific performance measures in youth judo athletes.

    Science.gov (United States)

    Fukuda, David H; Stout, Jeffrey R; Kendall, Kristina L; Smith, Abbie E; Wray, Mandy E; Hetrick, Robert P

    2013-02-01

    The purpose of this study was to characterize the adaptations imposed by 4 weeks of precompetition judo training in youth athletes. It was hypothesized that anthropometric and sport-specific performance would improve during the preparation for a junior national championship event. Twenty youth athletes (mean ± SD; chronological age: 13.1 ± 3.2 years; training age: 5.3 ± 3.5 years; judo experience: 7.8 ± 2.5 hours per week) completed pretesting and posttesting procedures. Child (12 years old; n = 8) and adolescent (13 years old; n = 12) groups were evaluated to determine the anthropometric and sport-specific performance changes caused by 4 weeks of judo training conducted in preparation for the junior national championships. The child group showed an increase in flexibility (11.5%), and the adolescent group showed a decrease in skinfold thickness (-12.2%); increased jumping power (26.7%), force (7.7%), and velocity (19.0%); and improved judo-specific ability (-5.9%), as measured by the Special Judo Fitness Test (SJFT) index. Additionally, the SJFT index for all the study participants was shown to be inversely correlated to handgrip strength (r = -0.681), rope pull performance (r = -0.545), and jump height (r = -0.503). These results support the use of preparatory judo training in the improvement of anthropometric and sport-specific measures in adolescent athletes. Furthermore, the outcomes from this study provide direction for coaches and trainers in their efforts to impact physical performance and judo skills in children and adolescents through precompetition training.

  15. Analysis of Classical Time-Trial Performance and Technique-Specific Physiological Determinants in Elite Female Cross-Country Skiers.

    Science.gov (United States)

    Sandbakk, Øyvind; Losnegard, Thomas; Skattebo, Øyvind; Hegge, Ann M; Tønnessen, Espen; Kocbach, Jan

    2016-01-01

    The present study investigated the contribution of performance on uphill, flat, and downhill sections to overall performance in an international 10-km classical time-trial in elite female cross-country skiers, as well as the relationships between performance on snow and laboratory-measured physiological variables in the double poling (DP) and diagonal (DIA) techniques. Ten elite female cross-country skiers were continuously measured by a global positioning system device during an international 10-km cross-country skiing time-trial in the classical technique. One month prior to the race, all skiers performed a 5-min submaximal and 3-min self-paced performance test while roller skiing on a treadmill, both in the DP and DIA techniques. The time spent on uphill (r = 0.98) and flat (r = 0.91) sections of the race correlated most strongly with the overall 10-km performance (both p skiing test and body-mass normalized peak oxygen uptake (VO2peak) in both techniques showed the strongest correlations with overall time-trial performance (r = 0.66-0.78), with DP capacity tending to have greatest impact on the flat and DIA capacity on uphill terrain (all p cross-country skiers can be explained by variations in technique-specific aerobic power.

  16. Preliminary exploration of HLA-A 1101-restricted human cytomegalovirus glycoprotein B-specific CD8⁺ T cells in allogeneic stem-cell transplant recipients.

    Science.gov (United States)

    Liu, Anbing; Hu, Jianhua; Wu, Wei; Huang, Yaping; Liang, Hanying; Wang, Huiqi; Yang, Rong; Fan, Jun

    2014-08-08

    T-cell responses directed against human cytomegalovirus (HCMV) glycoprotein B (gB) contribute to protective immunity against HCMV infection in both animal models and humans. However, the gB-specific human CD8(+) T cell responses remain poorly understood. gB antigen-specific CD8(+) T cells were stained with seven major histocompatibility complex (MHC)-peptide pentamers in 16 human leukocyte antigen (HLA)-A 1101-positive, HCMV-seropositive patients following hematopoietic stem cell transplantation (HSCT). Of these seven pentamers, the most frequent CD8(+) T-cell responses were directed against the gB332-340 peptide. These gB332-340-specific CD8(+) T cells were strongly associated with the presence of plasma HCMV immunoglobulin M in all HSCT recipients and exhibited a probable causal relationship with the level of pp65 antigenemia. Together, these data suggest a role for gB332-340-specific CD8(+) T cells in HCMV reactivation after HSCT. Furthermore, the pentamer assay may be valuable in detecting antigen-specific CD8(+) T cells.

  17. Analysis of classical time-trial performance and technique-specific physiological determinants in elite female cross-country skiers

    Directory of Open Access Journals (Sweden)

    Øyvind Sandbakk

    2016-08-01

    Full Text Available The present study investigated the contribution of performance on uphill, flat, and downhill sections to overall performance in an international 10-km classical time-trial in elite female cross-country skiers, as well as the relationships between performance on snow and laboratory-measured physiological variables in the double poling (DP and diagonal (DIA techniques. Ten elite female cross-country skiers were continuously measured by a global positioning system device during an international 10-km cross-country skiing time-trial in the classical technique. One month prior to the race, all skiers performed a 5-min submaximal and 3-min self-paced performance test while roller skiing on a treadmill, both in the DP and DIA techniques. The time spent on uphill (r=0.98 and flat (r=0.91 sections of the race correlated most strongly with the overall 10-km performance (both p<0.05. Approximately 56% of the racing time was spent uphill, and stepwise multiple regression revealed that uphill time explained 95.5% of the variance in overall performance (p<0.001. Distance covered during the 3-min roller-skiing test and body-mass normalized peak oxygen uptake (VO2peak in both techniques showed the strongest correlations with overall time-trial performance (r=0.66-0.78, with DP capacity tending to have greatest impact on the flat and DIA capacity on uphill terrain (all p<0.05. Our present findings reveal that the time spent uphill most strongly determine classical time-trial performance, and that the major portion of the performance differences among elite female cross-country skiers can be explained by variations in technique-specific aerobic power.

  18. Do maximal aerobic power and blood lactate concentration affect Specific Judo Fitness Test performance in female judo athletes?

    Science.gov (United States)

    Garbouj, H; Selmi, M A; Sassi, R Haj; Yahmed, M Haj; Chamari, K; Chaouachi, A

    2016-12-01

    The Special Judo Fitness Test (SJFT) has become the test most widely used by coaches and physical trainers for assessment of competitors' judo-specific physical aptitude and training programme prescription. The aim of this study was to investigate the relationship between the SJFT performance indices and both maximal aerobic power and the level of blood lactate concentrations in female judo athletes. Seventeen female judokas (age: 21.9±1.6 years, body mass: 74.6±27.4 kg, height: 164.5±8.6 cm; BMI: 27.1±8.0 kg · m(-2)) took part in this study. All participants performed the SJFT, 20 m multi-stage shuttle run test (MSRT), and 30 m straight sprint test (SST), from which we calculated both acceleration (10 m) and the maximal anaerobic speed (MAnS: flying 20 m sprint). A blood sample was taken 3 min after the SJFT. The number of throws was significantly correlated with estimated VO2max (r=0.795, p=0.0001) and both acceleration (r=0.63, p =0.006) and MAnS (r=0.76, p=0.0004). Peak blood lactate recorded after the SJFT was 13.90±1.39 mmol · l(-1). No significant correlation was found between blood lactate concentration and the SJFT performance indices. The lack of significant correlation between blood lactate and SJFT performance suggests that lactic anaerobic metabolism has no effect on this type of judo-specific supra-maximal exercise. The observed results can provide coaches and strength and conditioning professionals with relevant information for the interpretation of SJFT performance and the prescription of specific training programmes for female judo athletes.

  19. Climbing-specific finger flexor performance and forearm muscle oxygenation in elite male and female sport climbers.

    Science.gov (United States)

    Philippe, Marc; Wegst, Daniel; Müller, Tom; Raschner, Christian; Burtscher, Martin

    2012-08-01

    Climbing performance relies to a great extent on the performance of the finger flexor muscles. Only a few studies investigated this performance in top class climbers and only one study compared gender-specific differences. This study investigated the climbing-specific finger flexor strength and endurance and related muscular oxygenation in 12 elite female and male climbers and 12 non-climbers. After the assessment of maximum voluntary finger flexor contraction (MVC), two isometric finger flexor endurance tests were performed at 40% MVC until exhaustion. A continuous isometric test was followed by an intermittent isometric test (10 s contraction, 3 s rest). Changes in oxygenation of finger flexor muscles were recorded using near infrared spectroscopy. MVC and strength-to-weight ratio were greater in climbers than non-climbers (P = 0.003; P < 0.001) and greater in men than women (P < 0.001; P = 0.002). Time to task failure for the intermittent test and the force-time integrals for the continuous and the intermittent test were also significantly greater in climbers (P = 0.030; P = 0.027; P = 0.005). During the intermittent test, re-oxygenation of the working muscles was faster in climbers (P < 0.05) without gender-specific differences. Close correlations were demonstrated between the best on-sight climbing performance and strength-to-weight ratio (r (2) = 0.946, P < 0.001) only in female climbers. The superior intermittent finger flexor endurance of climbers over non-climbers may be explained by the faster re-oxygenation of the finger flexor muscles during the short rest phases.

  20. Preliminary design package for prototype solar heating and cooling systems

    Science.gov (United States)

    1978-01-01

    A summary is given of the preliminary analysis and design activity on solar heating and cooling systems. The analysis was made without site specific data other than weather; therefore, the results indicate performance expected under these special conditions. Major items include a market analysis, design approaches, trade studies and other special data required to evaluate the preliminary analysis and design. The program calls for the development and delivery of eight prototype solar heating and cooling systems for installation and operational test. Two heating and six heating and cooling units will be delivered for Single Family Residences, Multiple-family Residences and commercial applications.

  1. A comparison of student performance on discipline-specific versus integrated exams in a medical school course.

    Science.gov (United States)

    Thompson, Andrew R; Braun, Mark W; O'Loughlin, Valerie D

    2013-12-01

    Curricular reform is a widespread trend among medical schools. Assessing the impact that pedagogical changes have on students is a vital step in review process. This study examined how a shift from discipline-focused instruction and assessment to integrated instruction and assessment affected student performance in a second-year medical school pathology course. We investigated this by comparing pathology exam scores between students exposed to traditional discipline-specific instruction and exams (DSE) versus integrated instruction and exams (IE). Exam content was controlled, and individual questions were evaluated using a modified version of Bloom's taxonomy. Additionally, we compared United States Medical Licensing Examination (USMLE) step 1 scores between DSE and IE groups. Our findings indicate that DSE students performed better than IE students on complete pathology exams. However, when exam content was controlled, exam scores were equivalent between groups. We also discovered that the integrated exams were composed of a significantly greater proportion of questions classified on the higher levels of Bloom's taxonomy and that IE students performed better on these questions overall. USMLE step 1 exam scores were similar between groups. The finding of a significant difference in content complexity between discipline-specific and integrated exams adds to recent literature indicating that there are a number of potential biases related to curricular comparison studies that must be considered. Future investigation involving larger sample sizes and multiple disciplines should be performed to explore this matter further.

  2. Tip clearance effects on loads and performances of semi-open impeller centrifugal pumps at different specific speeds

    Science.gov (United States)

    Boitel, G.; Fedala, D.; Myon, N.

    2016-11-01

    Relevant industrial standards or customer's specifications could strictly forbid any device adjusting the axial rotor/stator position, so that tip clearance between semi-open impeller and casing might become a result of the pump machining tolerances and assembling process, leading to big tip clearance variations compared to its nominal value. Consequently, large disparities of global performances (head, power, efficiency) and axial loads are observed with high risk of both specifications noncompliance and bearing damages. This work aims at quantifying these variations by taking into account tip clearance value and pump specific speed. Computational Fluid Dynamics is used to investigate this phenomenon by means of steady simulations led on a semi-open centrifugal pump numerical model including secondary flows, based on a k-omega SST turbulence model. Four different specific speed pump sizes are simulated (from 8 to 50, SI units), with three tip clearances for each size on a wide flow range (from 40% to 120% of the best efficiency point). The numerical results clearly show that head, power and efficiency increase as the tip clearance decreases for the whole flow range. This effect is more significant when the specific speed is low. Meanwhile, the resulting axial thrust on the impeller is very sensitive to the tip clearance and can even lead to direction inversion.

  3. Solar Pilot Plant, Phase I: preliminary design report. Volume VII. Pilot plant cost, commercial plant cost and performance. CDRL item 2

    Energy Technology Data Exchange (ETDEWEB)

    None

    1977-06-01

    Cost estimates are presented for the Solar Pilot Plant by cost breakdown structure element, with a commitment schedule and an expenditure schedule. Cost estimates are given for a Commercial Plant, including several point costs for plants with various solar multiples and storage times. Specific questions (ERDA) pertaining to commercial plant design and performance data are addressed. The cost estimates are supplemented by two books of vendor and subcontractor cost data.

  4. C-Tactile Mediated Erotic Touch Perception Relates to Sexual Desire and Performance in a Gender-Specific Way.

    Science.gov (United States)

    Bendas, Johanna; Georgiadis, Janniko R; Ritschel, Gerhard; Olausson, Håkan; Weidner, Kerstin; Croy, Ilona

    2017-05-01

    Unmyelinated low-threshold mechanoreceptors-the so-called C-tactile (CT) afferents-play a crucial role in the perception and conduction of caressing and pleasant touch sensations and significantly contribute to the concept of erotic touch perception. To investigate the relations between sexual desire and sexual performance and the perception of touch mediated by CT afferents. Seventy healthy participants (28 men, 42 women; mean age ± SD = 24.84 ± 4.08 years, range = 18-36 years) underwent standardized and highly controlled stroking stimulation that varied in the amount of CT fiber stimulation by changing stroking velocity (CT optimal = 1, 3 and 10 cm/s; CT suboptimal = 0.1, 0.3, and 30 cm/s). Participants rated the perceived pleasantness, eroticism, and intensity of the applied tactile stimulation on a visual analog scale, completed the Sexual Desire Inventory, and answered questions about sexual performance. Ratings of perceived eroticism of touch were related to self-report levels of sexual desire and sexual performance. Pleasantness and eroticism ratings showed similar dependence on stroking velocity that aligned with the activity of CT afferents. Erotic touch perception was related to sexual desire and sexual performance in a gender-specific way. In women, differences in eroticism ratings between CT optimal and suboptimal velocities correlated positively with desire for sexual interaction. In contrast, in men, this difference correlated to a decreased frequency and longer duration of partnered sexual activities. The present results lay the foundation for future research assessing these relations in patients with specific impairments of sexual functioning (eg, hypoactive sexual desire disorder). The strength of the study is the combination of standardized neurophysiologic methods and behavioral data. A clear limitation of the study design is the exclusion of exact data on the female menstrual cycle and the recruitment of an inhomogeneous sample

  5. SU-E-I-40: New Method for Measurement of Task-Specific, High-Resolution Detector System Performance

    Energy Technology Data Exchange (ETDEWEB)

    Loughran, B; Singh, V; Jain, A; Bednarek, D; Rudin, S [University at Buffalo, Buffalo, NY (United States)

    2014-06-01

    Purpose: Although generalized linear system analytic metrics such as GMTF and GDQE can evaluate performance of the whole imaging system including detector, scatter and focal-spot, a simplified task-specific measured metric may help to better compare detector systems. Methods: Low quantum-noise images of a neuro-vascular stent with a modified ANSI head phantom were obtained from the average of many exposures taken with the high-resolution Micro-Angiographic Fluoroscope (MAF) and with a Flat Panel Detector (FPD). The square of the Fourier Transform of each averaged image, equivalent to the measured product of the system GMTF and the object function in spatial-frequency space, was then divided by the normalized noise power spectra (NNPS) for each respective system to obtain a task-specific generalized signal-to-noise ratio. A generalized measured relative object detectability (GM-ROD) was obtained by taking the ratio of the integral of the resulting expressions for each detector system to give an overall metric that enables a realistic systems comparison for the given detection task. Results: The GM-ROD provides comparison of relative performance of detector systems from actual measurements of the object function as imaged by those detector systems. This metric includes noise correlations and spatial frequencies relevant to the specific object. Additionally, the integration bounds for the GM-ROD can be selected to emphasis the higher frequency band of each detector if high-resolution image details are to be evaluated. Examples of this new metric are discussed with a comparison of the MAF to the FPD for neuro-vascular interventional imaging. Conclusion: The GM-ROD is a new direct-measured task-specific metric that can provide clinically relevant comparison of the relative performance of imaging systems. Supported by NIH Grant: 2R01EB002873 and an equipment grant from Toshiba Medical Systems Corporation.

  6. Preparation, crystallization, and preliminary X-ray diffraction study of mutant carboxypeptidase T containing the primary specificity pocket of carboxypeptidase B

    Energy Technology Data Exchange (ETDEWEB)

    Akparov, V. Kh., E-mail: valery@akparov.ru; Grishin, A. M. [Scientific Center of Russian Federation Research Institute for Genetics and Selection of Industrial Microorganisms (Russian Federation); Timofeev, V. I., E-mail: inna@ns.crys.ras.ru; Kuranova, I. P. [Russian Academy of Sciences, Shubnikov Institute of Crystallography (Russian Federation)

    2010-09-15

    Recombinant G215S, A251G, T257A, D260G, T262D mutant carboxypeptidase T from Thermoactinomyces vulgaris containing mutations in the primary specificity pocket was prepared and crystallized. Single crystals with a size of up to 0.3 mm were grown and investigated by X-ray diffraction. Recombinant mutant carboxypeptidase T containing the primary specificity subsite compositionally identical to that of pancreatic carboxypeptidase B crystallizes in the same space group as the natural enzyme. The crystals belong to sp. gr. P6{sub 3}22; the unit-cell parameters are a = b = 157.867 A, c = 104.304 A, {alpha} = {beta} = 90 deg., {gamma} = 120 deg. X-ray diffraction data suitable for determining the three-dimensional structure at atomic resolution were collected from one crystal.

  7. Effect of a dual task on quantitative Timed Up and Go performance in community-dwelling older adults: A preliminary study.

    Science.gov (United States)

    Smith, Erin; Walsh, Lorcan; Doyle, Julie; Greene, Barry; Blake, Catherine

    2017-08-01

    The Timed Up and Go test (TUG) is used as a measure of functional ability in older adults; however, the method of measurement does not allow us to determine which aspects of the test deficits occur in. The aim of the present study was to examine the ability of the quantitative TUG (QTUG) to measure performance during the TUG test under three different conditions - single task, motor task and cognitive dual task - and to compare performance between fallers and non-fallers in high-functioning community-dwelling older adults. A total of 37 community-dwelling older adults, 16 with a self-reported falls history in the previous year, were recruited. Participants underwent a falls risk assessment with a physiotherapist including the QTUG under three conditions (single task, motor task, cognitive dual-task). A total of 10 clinical parameters were chosen for analysis using mancova and a series of ancova, with age, sex and body mass index included as covariates. The mancova analysis showed a significant difference across the three task conditions (Wilk's Lambda F20,186  = 3.37, P time in double support. When faller and non-faller differences were explored, cadence and stride velocity was greater, and stride time longer in those with a prior history of falls. In community-dwelling older adults, these preliminary results show that a cognitive dual-task significantly (P time-to-stand observed with a motor task. Although no statistical difference was found between fallers and non-fallers for many of the parameters, cadence, stride time and stride velocity were statistically different (P < 0.05). A larger sample size and more assessment points might lead to more definitive findings. These results highlight the need for further research to examine QTUG performance under dual-task conditions between fallers and non-fallers in this population, and to look at the ability of dual-task QTUG assessment to measure change longitudinally and the effectiveness of therapeutic

  8. Nanoclay-based hierarchical interconnected mesoporous CNT/PPy electrode with improved specific capacitance for high performance supercapacitors.

    Science.gov (United States)

    Oraon, Ramesh; De Adhikari, Amrita; Tiwari, Santosh Kumar; Nayak, Ganesh Chandra

    2016-05-31

    A natural layered clay known as montmorillonite, a lamellar aluminosilicate with ∼1 nm thickness, has attracted intense attention in ongoing research due to its large natural abundance and environmental friendliness. Endowed with highly active surface sites the nanoclay has been extensively used in various fields viz. catalysis, biosensors etc. even though the role played by nanoclay on energy storage performance has not been elucidated. In this present work, a series of nanoclay (Closite 30B) based hierarchical open interconnected mesoporous electrode materials for supercapacitors (SCs) has been synthesized in the presence of carbon nanotubes (CNTs) and polypyrrole (PPy) by a facile in situ and ex situ approach. The role of nanoclay was explored as a dopant and its substantial doping effect exerted on the electrochemical performance towards energy storage was investigated. A coating of PPy over CNTs and nanoclay was confirmed from FESEM analysis which revealed the genesis of a nanoclay-supported hierarchical interconnected mesoporous framework. Furthermore, a PPy-coated CNT array in the presence of nanoclay was found to be highly porous with a high specific surface area without obvious deterioration. These interconnected structures can contribute to better penetration of electrolyte ions by shortening the path length for rapid transport of ions and electrons even at high rates. Cyclic voltammetry measurements revealed that nanoclay based in situ composite (CNP) and ex situ composite (CPN) exhibited a maximum specific capacitance of 425 F g(-1) and 317 F g(-1), respectively at a scan rate of 10 mV s(-1), which is comparatively higher than that of CP (i.e. PPy-coated CNTs) (76.77 F g(-1)). Similarly, a 273% increase in the specific capacitance of PPy was achieved after nanoclay incorporation in the nanocomposite NP (i.e. PPy-coated nanoclay) as compared to virgin PPy. These results are in good agreement with the specific capacitance performance by galvanostatic

  9. Impact of Technique-Specific Operative Videos on First-Year Dental Students' Performance of Restorative Procedures.

    Science.gov (United States)

    Patel, Shalizeh A; Barros, Juliana A; Clark, Christina M; Frey, Gary N; Streckfus, Charles F; Quock, Ryan L

    2015-09-01

    The aim of this study was to examine the impact of psychomotor operative video demonstrations on first-year dental students who are performing specific procedures for the first time in a preclinical setting. The class was randomly divided into two groups, and three restorative procedures were selected. On the date on which each procedure was to be performed in the preclinical laboratory for the first time, one group (experimental, n=50) was shown a technique video for that specific procedure immediately before commencing the exercise; the control cohort (n=50) did not view the video. Technical performance on procedures was evaluated by students and two calibrated and blinded examiners. The students' perceptions of the experience were also collected in a survey. All first-year students participated in the study, for a 100% response rate. A Mann-Whitney U test did not show any group differences in technical performance (mean values on preparation: 77.1 vs. 77.8; amalgam: 82.7 vs. 82.8; composite: 79.7 vs. 78.0). A Spearman rho test revealed a significantly higher correlation in 13 out of 25 evaluation categories between student self-assessment and blinded examiner assessment for the experimental group. A chi-square test of questionnaire responses revealed a positive student perception of administering these videos for the preparation (X(2)=4.8, pstudent performance on preclinical operative procedures, but they were well received by students and augmented self-assessment ability. These findings suggest that videos can be a useful teaching aid in a preclinical environment, especially regarding comprehension of concepts.

  10. Performance-Based Specifications of Workability Characteristics of Prestressed, Precast Self-Consolidating Concrete—A North American Prospective

    Directory of Open Access Journals (Sweden)

    Wu-Jian Long

    2014-03-01

    Full Text Available Adequate selection of material constituents and test methods are necessary for workability specifications and performance of hardened concrete. An experimental program was performed to evaluate the suitability of various test methods for workability assessment and to propose performance specifications of prestressed concrete. In total, 33 self-consolidating concrete (SCC mixtures made with various mixture proportioning parameters, including maximum size and type of aggregate, type and content of binder, and w/cm were evaluated. Correlations among various test results used in evaluating the workability responses are established. It is recommended that SCC should have slump flow values of 635–760 mm. To ensure proper filling capacity greater than 80%, such concrete should have a passing ability that corresponds to L-box blocking ratio (h2/h1 ≥ 0.5, J-Ring flow of 570–685 mm, slump flow minus J-Ring flow diameter ≤75 mm. Moreover, Stable SCC should develop a column segregation index lower than 5%, and rate of settlement at 30 min of 0.27%/h for SCC proportioned with 12.5 or 9.5 mm MSA. It is recommended that SCC should have a plastic viscosity of 100–225 Pa·s and 100–400 Pa·s for concrete made with crushed aggregate and gravel, respectively, to ensure proper workability.

  11. Sensitivity and Specificity of Screening Mammographies and Ultrasonographies Performed in Women at Seven Health Promotion Centers for One year

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Hyun Sung; Kang, Bong Joo; Yim, Hyeon Woo [Catholic University of Korea College of Medicine, Seoul (Korea, Republic of)

    2010-03-15

    We wanted to evaluate the sensitivity and specificity of screening mammography and ultrasonography for breast examinations and we assessed the clinical usefulness of breast ultrasound for cancer screening. Of all the women who visited the health promotion center of seven medical institutions from Mar 2004 to Feb 2005, we compared the sensitivity and specificity between a single use of mammography and mammography with ultrasonography for the patients who underwent both mammography and ultrasonography. Here, the reference criteria were the follow-up and the histopathology, which were performed after one year. A total of 1123 patients underwent both mammography and ultrasonography and they could be followed up for a year. For the 1123 patients who underwent both mammography and ultrasonography, the sensitivity and specificity of a single use of mammography were 14.3% and 86.9%, respectively. The sensitivity and specificity of mammography with ultrasonography were 85.7% and 85.9%, respectively. These results showed that the sensitivity was significantly increased when mammography was combined with ultrasonography (< 0.05). The sensitivity was improved for the cases that underwent both mammography and ultrasonography

  12. Sport-Specific Conditioning Variables Predict Offensive and Defensive Performance in High-Level Youth Water Polo Athletes.

    Science.gov (United States)

    Sekulic, Damir; Kontic, Dean; Esco, Michael R; Zenic, Natasa; Milanovic, Zoran; Zvan, Milan

    2016-05-01

    Specific-conditioning capacities (SCC) are known to be generally important in water polo (WP), yet the independent associations to offensive and defensive performance is unknown. This study aimed to determine whether offense and defense abilities in WP were independently associated with SCC and anthropometrics. The participants were 82 high-level male youth WP players (all 17-19 years of age; body height, 186.3 ± 6.07 cm; body mass, 84.8 ± 9.6 kg). The independent variables were body height and body mass, and 5 sport-specific fitness tests: sprint swimming over 15 meters; 4 × 50-meter anaerobic-endurance test; vertical in-water-jump; maximum intensity isometric force in upright swimming using an eggbeater kick; and test of throwing velocity. The 6 dependent variables comprised parameters of defensive and offensive performance, such as polyvalence, i.e., ability to play on different positions in defensive tasks (PD) and offensive tasks (PO), efficacy in primary playing position in defensive (ED) and offensive (EO) tasks, and agility in defensive (AD) and offensive (AO) tasks. Analyses showed appropriate reliability for independent (intraclass coefficient of 0.82-0.91) and dependent variables (Cronbach alpha of 0.81-0.95). Multiple regressions were significant for ED (R = 0.25; p performance was positively related to AD (β = -0.26; p ≤ 0.05), whereas advanced sprint swimming was related to better AO (β = -0.38; p ≤ 0.05). In-water-jumping performance held the significant positive relationship to EO (β = 0.31; p ≤ 0.05), ED (β = 0.33; p ≤ 0.05), and AD (β = 0.37; p ≤ 0.05). Strength and conditioning professionals working in WP should be aware of established importance of SCC in performing unique duties in WP. The SCC should be specifically developed to meet the needs of offensive and defensive performance in young WP athletes.

  13. Sensitive determination of specific radioactivity of positron emission tomography radiopharmaceuticals by radio high-performance liquid chromatography with fluorescence detection

    Energy Technology Data Exchange (ETDEWEB)

    Nakao, Ryuji [Molecular Imaging Center, National Institute of Radiological Sciences, Chiba 263-8555 (Japan)], E-mail: nakaor@nirs.go.jp; Furutsuka, Kenji [Molecular Imaging Center, National Institute of Radiological Sciences, Chiba 263-8555 (Japan); Sumitomo Accelerator Service, Tokyo 141-8686 (Japan); Yamaguchi, Masatoshi [Faculty of Pharmaceutical Sciences, Fukuoka University, Fukuoka 814-0180 (Japan); Suzuki, Kazutoshi [Molecular Imaging Center, National Institute of Radiological Sciences, Chiba 263-8555 (Japan)

    2008-10-15

    A sensitive quality control method is often required in positron emission tomography (PET) radiopharmaceutical analysis due to the high specific radioactivity of synthetic products. The applicability of a radio high-performance liquid chromatography (HPLC) method with fluorescence detection was evaluated for a wide variety of PET radiopharmaceuticals. In 29 different radiopharmaceuticals studied, 20 compounds exhibited native fluorescence. These properties enabled sensitive determination of their chemical masses by direct fluorimetric detection after separation by HPLC. For some substances, detection limits were below nanograms per milliliter level, at least 40 times better than current UV absorbance detection. Sufficient reproducibility and linearity were obtained for the analysis of pharmaceutical fluid. Post-column fluorimetric derivatization was also established for the quantitative determination of FDG and ClDG in [{sup 18}F]FDG samples. These methods could be applied successfully to the analysis of PET radiopharmaceuticals with ultra-high specific radioactivity.

  14. The Suitability of the Remedy of Specific Performance to Breach of a "Player's Contract" with Specific Reference to the Mapoe and Santos cases

    Directory of Open Access Journals (Sweden)

    K Mould

    2011-04-01

    Full Text Available During the 1990s, rugby union formation in the Republic of South Africa developed rapidly from a system of strict amateurism to one of professionalism. Professional participants in the sport received salaries for participation, and rugby became a business like any other. As in all forms of business, rugby had to be regulated moreefficiently than had previously been the case. Tighter regulations were instituted by governing bodies, and ultimately labour legislation became applicable to professional rugby. A professional sportsman or woman participating in a team sport is generallyconsidered an employee. This means that the same principles that govern employees in general should also apply to professional sportsmen and women. The exact nature of the "player's contract", a term generally used to describe the contract of employment between a professional sportsman or sportswoman and his or her employer, deserves closer attention. It has been argued with much merit that the "player's contract", while in essence a contract of employment, possesses certain sui generis characteristics. The first aim of this article is to demonstrate how this statement is in fact a substantial one. If it is concluded that the "player's contract" isin fact a sui generis contract of employment, the most suitable remedy in case of breach of contract must be determined. The second aim of this article is to indicate why the remedy of specific performance, which is generally not granted in cases where the defaulting party has to provide services of a personal nature, is the most suitable remedy in case of breach of "player's contracts". To substantiate this statement, recent applicable case law is investigated and discussed, particularly the recent case of Vrystaat Cheetahs (Edms Beperk v Mapoe. Suggestions are finally offered as to how breach of "player's contracts" should be approached by South African courts in future.

  15. Urinary oxytocin positively correlates with performance in facial visual search in unmarried males, without specific reaction to infant face

    Directory of Open Access Journals (Sweden)

    Atsuko eSaito

    2014-07-01

    Full Text Available The neuropeptide oxytocin plays a central role in prosocial and parental behavior in non-human mammals as well as humans. It has been suggested that oxytocin may affect visual processing of infant faces and emotional reaction to infants. Healthy male volunteers (N = 13 were tested for their ability to detect infant or adult faces among adult or infant faces (facial visual search task. Urine samples were collected from all participants before the study to measure the concentration of oxytocin. Urinary oxytocin positively correlated with performance in the facial visual search task. However, task performance and its correlation with oxytocin concentration did not differ between infant faces and adult faces. Our data suggests that endogenous oxytocin is related to facial visual cognition, but does not promote infant-specific responses in unmarried men who are not fathers.

  16. Carbohydrate ingestion and pre-cooling improves exercise capacity following soccer-specific intermittent exercise performed in the heat.

    Science.gov (United States)

    Clarke, N D; Maclaren, D P M; Reilly, T; Drust, B

    2011-07-01

    Ingestion of carbohydrate and reducing core body temperature pre-exercise, either separately or combined, may have ergogenic effects during prolonged intermittent exercise in hot conditions. The aim of this investigation was to examine the effect of carbohydrate ingestion and pre-cooling on the physiological responses to soccer-specific intermittent exercise and the impact on subsequent high-intensity exercise performance in the heat. Twelve male soccer players performed a soccer-specific intermittent protocol for 90 min in the heat (30.5°C and 42.2% r.h.) on four occasions. On two occasions, the participants underwent a pre-cooling manoeuvre. During these sessions either a carbohydrate-electrolyte solution (CHOc) or a placebo was consumed at (PLAc). During the remaining sessions either the carbohydrate-electrolyte solution (CHO) or placebo (PLA) was consumed. At 15-min intervals throughout the protocol participants performed a mental concentration test. Following the soccer-specific protocol participants performed a self-chosen pace test and a test of high-intensity exercise capacity. The period of pre-cooling significantly reduced core temperature, muscle temperature and thermal sensation (P < 0.05). Self-chosen pace was greater with CHOc (12.5 ± 0.5 km h(-1)) compared with CHO (11.3 ± 0.4 km h(-1)), PLA (11.3 ± 0.4 km h(-1)) and PLAc (11.6 ± 0.5 km h(-1)) (P < 0.05). High-intensity exercise capacity was improved with CHOc and CHO when compared with PLA (CHOc; 79.8 ± 7 s, CHO; 72.1 ± 5 s, PLAc; 70.1 ± 8 s, PLA; 57.1 ± 5 s; P < 0.05). Mental concentration during the protocol was also enhanced during CHOc compared with PLA (P < 0.05). These results suggest pre-cooling in conjunction with the ingestion of carbohydrate during exercise enhances exercise capacity and helps maintain mental performance during intermittent exercise in hot conditions.

  17. Are there specific conditions for which expertise in gymnastics could have an effect on postural control and performance?

    Science.gov (United States)

    Asseman, François B; Caron, Olivier; Crémieux, Jacques

    2008-01-01

    The first aim of this study was to analyse the effect of elite training, linked to expertise, in gymnastics on postural performance and control. For this purpose, body sway of expert gymnasts was compared to other sportsmen, non-experts and non-gymnasts, in two different postures: bipedal (easy and unspecific to gymnasts) and unipedal (difficult and fairly specific). The second aim was to compare the groups in the same tasks but in a visual condition for which they were not trained, i.e. with eyes closed. Postural performance was assessed by centre of gravity motion, which was computed from centre of pressure motion, estimating postural control. A significant difference between the two groups was observed for postural performance in the unipedal posture and with eyes open only. Regardless of their posture, the groups were similarly affected by removal of vision. Expertise in gymnastics seemed to improve postural performances only in situations for which their practise is related to, i.e. unipedal with eyes open. These reveal the importance of choosing a relevant postural configuration and visual condition according to the people's training or by extension experience.

  18. Near Term Hybrid Passenger Vehicle Development Program. Phase I, Final report. Appendix A: mission analysis and performance specification studies. Volume I

    Energy Technology Data Exchange (ETDEWEB)

    Traversi, M.; Barbarek, L.A.C.

    1979-04-20

    Studies are described which were performed for the Near Term Hybrid Vehicle program to determine passenger car usage patterns and to correlate these trip mission characteristics with vehicle design and performance specifications. (LCL)

  19. Good performance of rapid prostate-specific antigen test for detection of semen exposure in women: implications for qualitative research.

    Science.gov (United States)

    Hobbs, Marcia M; Steiner, Markus J; Rich, Kimberly D; Gallo, Maria F; Alam, Anadil; Rahman, Motiur; Menezes, Prema; Chipato, Tsungai; Warner, Lee; Macaluso, Maurizio

    2009-08-01

    Prostate-specific antigen (PSA) is a valid biomarker of semen exposure in women and has been used to assess reliability of self-reported sexual behavior as well as serve as a proxy measure for condom efficacy. Quantitative PSA tests are expensive and require specialized equipment. A simple, rapid, and inexpensive test for PSA would facilitate semen biomarker evaluation in a variety of research settings. This study evaluated the performance of a rapid PSA test compared with a quantitative assay to identify semen in vaginal swab specimens. We tested 581 vaginal swabs collected from 492 women participating in 2 separate research studies in Bangladesh and Zimbabwe. PSA in vaginal secretions was detected using the quantitative IMx (Abbott Laboratories) assay and the ABAcard p30 (Abacus Diagnostics) rapid immunochromatographic strip test. The ABAcard test was 100% sensitive (95% confidence interval [CI], 98%-100%) and 96% specific (95% CI, 93%-97%) compared with the quantitative test in detecting >1.0 ng PSA/mL vaginal swab eluate. Rapid PSA results were semiquantitative and correlated well with PSA concentrations (kappa = 0.88; 95% CI, 0.85-0.90). Rapid PSA detection requires no instrumentation and can be performed easily and economically. Having rapid PSA results available immediately following interview provides opportunities to explore discrepancies between the objective marker of recent semen exposure and self-reported behaviors.

  20. Specificity in autobiographical memory narratives correlates with performance on the autobiographical memory test and prospectively predicts depressive symptoms.

    Science.gov (United States)

    Sumner, Jennifer A; Mineka, Susan; McAdams, Dan P

    2013-01-01

    Reduced autobiographical memory specificity (AMS) is an important cognitive marker in depression that is typically measured with the Autobiographical Memory Test (AMT; Williams & Broadbent, 1986). The AMT is widely used, but the over-reliance on a single methodology for assessing AMS is a limitation in the field. The current study investigated memory narratives as an alternative measure of AMS in an undergraduate student sample selected for being high or low on a measure of depressive symptoms (N=55). We employed a multi-method design to compare narrative- and AMT-based measures of AMS. Participants generated personally significant self-defining memory narratives, and also completed two versions of the AMT (with and without instructions to retrieve specific memories). Greater AMS in self-defining memory narratives correlated with greater AMS in performance on both versions of the AMT in the full sample, and the patterns of relationships between the different AMS measures were generally similar in low and high dysphoric participants. Furthermore, AMS in self-defining memory narratives was prospectively associated with depressive symptom levels. Specifically, greater AMS in self-defining memory narratives predicted fewer depressive symptoms at a 10-week follow-up over and above baseline symptom levels. Implications for future research and clinical applications are discussed.

  1. Syndrome-Specific Deficits of Performance and Effects of Practice on Arm Movements with Deafferentation due to Posterior Thalamic Lesion

    Directory of Open Access Journals (Sweden)

    Thomas Platz

    1997-01-01

    Full Text Available Aiming and tapping movements were analysed repeatedly over a three-week period in a patient who was hemideafferented due to an ischaemic posterior thalamic lesion. Contrasting behaviour observed in six healthy subjects, nine hemiparetic patients and one patient with hemianopic stroke, allowed the determination of behavioural deficits related to deafferentation. Finger tapping was not impaired specifically and did not improve with practice in the deafferented patient. When aiming movements were investigated, accuracy of the first, largely preprogrammed, phase of movement and timing of the late homing-in phase were impaired specifically in the deafferented patient. Practice led to a step-like change in preprogramming amplitude of the ballistic movement component, a gradual improvement of temporal efficiency of the early movement phase and a more marked improvement of the homing-in phase. Qualitatively comparable but quantitatively less marked effects of practice were documented for hemiparetic patients. These results demonstrated that deafferentation affects preprogrammed aspects of movement and those influenced by current control and that motor learning is possible with central deafferentation, even for aspects of performance that are impaired specifically. It is postulated that motor learning was mediated by changes in strategy (motor programming and improved efficiency of intact motor control processes (visuomotor control.

  2. Preliminary study of neck muscle size and strength measurements in females with chronic non-specific neck pain and healthy control subjects.

    Science.gov (United States)

    Rezasoltani, Asghar; Ali-Reza, Ahmadipor; Khosro, Khademi-Kalantari; Abbass, Rahimi

    2010-08-01

    Neck muscle weakness and atrophy are two common causes of pain and disability among office workers. The aim of this study was to compare the strength of the neck extensor and flexor muscles and the size of the semispinalis capitis muscle (SECM) in patients with chronic non-specific neck pain (CNNP) and healthy subjects. Twenty female office workers (10 patients with CNNP and 10 healthy subjects) participated in this study. The strength of the neck extensor and flexor muscles was measured by an isometric device and the SECM size was measured by ultrasonography. Neck muscle strength, size of the SECM and the ratios of neck strength to body weight, neck extensor strength to SECM size, SECM size to body weight and neck flexor to extensor strength were all significantly lower in patients compared to controls (P neck strength, the size of the SECM and the ratio of neck muscle strength to SECM size appear to be useful parameters in appraising patients with CNNP.

  3. A Domain-Specific Language for Incremental and Modular Design of Large-Scale Verifiably-Safe Flow Networks (Preliminary Report)

    CERN Document Server

    Bestavros, Azer; 10.4204/EPTCS.66.2

    2011-01-01

    We define a domain-specific language (DSL) to inductively assemble flow networks from small networks or modules to produce arbitrarily large ones, with interchangeable functionally-equivalent parts. Our small networks or modules are "small" only as the building blocks in this inductive definition (there is no limit on their size). Associated with our DSL is a type theory, a system of formal annotations to express desirable properties of flow networks together with rules that enforce them as invariants across their interfaces, i.e, the rules guarantee the properties are preserved as we build larger networks from smaller ones. A prerequisite for a type theory is a formal semantics, i.e, a rigorous definition of the entities that qualify as feasible flows through the networks, possibly restricted to satisfy additional efficiency or safety requirements. This can be carried out in one of two ways, as a denotational semantics or as an operational (or reduction) semantics; we choose the first in preference to the se...

  4. Tool-specific performance of vibration-reducing gloves for attenuating palm-transmitted vibrations in three orthogonal directions.

    Science.gov (United States)

    Dong, Ren G; Welcome, Daniel E; Peterson, Donald R; Xu, Xueyan S; McDowell, Thomas W; Warren, Christopher; Asaki, Takafumi; Kudernatsch, Simon; Brammer, Antony

    2014-11-01

    Vibration-reducing (VR) gloves have been increasingly used to help reduce vibration exposure, but it remains unclear how effective these gloves are. The purpose of this study was to estimate tool-specific performances of VR gloves for reducing the vibrations transmitted to the palm of the hand in three orthogonal directions (3-D) in an attempt to assess glove effectiveness and aid in the appropriate selection of these gloves. Four typical VR gloves were considered in this study, two of which can be classified as anti-vibration (AV) gloves according to the current AV glove test standard. The average transmissibility spectrum of each glove in each direction was synthesized based on spectra measured in this study and other spectra collected from reported studies. More than seventy vibration spectra of various tools or machines were considered in the estimations, which were also measured in this study or collected from reported studies. The glove performance assessments were based on the percent reduction of frequency-weighted acceleration as is required in the current standard for assessing the risk of vibration exposures. The estimated tool-specific vibration reductions of the gloves indicate that the VR gloves could slightly reduce (<5%) or marginally amplify (<10%) the vibrations generated from low-frequency (<25 Hz) tools or those vibrating primarily along the axis of the tool handle. With other tools, the VR gloves could reduce palm-transmitted vibrations in the range of 5%-58%, primarily depending on the specific tool and its vibration spectra in the three directions. The two AV gloves were not more effective than the other gloves with some of the tools considered in this study. The implications of the results are discussed.

  5. Relationships and Predictive Capabilities of Jump Assessments to Soccer-Specific Field Test Performance in Division I Collegiate Players

    Directory of Open Access Journals (Sweden)

    Robert G. Lockie

    2016-12-01

    Full Text Available Leg power is an important characteristic for soccer, and jump tests can measure this capacity. Limited research has analyzed relationships between jumping and soccer-specific field test performance in collegiate male players. Nineteen Division I players completed tests of: leg power (vertical jump (VJ, standing broad jump (SBJ, left- and right-leg triple hop (TH; linear (30 m sprint; 0–5 m, 5–10 m, 0–10, 0–30 m intervals and change-of-direction (505 speed; soccer-specific fitness (Yo-Yo Intermittent Recovery Test Level 2; and 7 × 30-m sprints to measure repeated-sprint ability (RSA; total time (TT, performance decrement (PD. Pearson’s correlations (r determined jump and field test relationships; stepwise regression ascertained jump predictors of the tests (p < 0.05. All jumps correlated with the 0–5, 0–10, and 0–30 m sprint intervals (r = −0.65–−0.90. VJ, SBJ, and left- and right-leg TH correlated with RSA TT (r = −0.51–−0.59. Right-leg TH predicted the 0–5 and 0–10 m intervals (R2 = 0.55–0.81; the VJ predicted the 0–30 m interval and RSA TT (R2 = 0.41–0.84. Between-leg TH asymmetry correlated with and predicted left-leg 505 and RSA PD (r = −0.68–0.62; R2 = 0.39–0.46. Improvements in jumping ability could contribute to faster speed and RSA performance in collegiate soccer players.

  6. Development and preliminary data on the use of a mobile app specifically designed to increase community awareness of invasive pneumococcal disease and its prevention.

    Science.gov (United States)

    Panatto, Donatella; Domnich, Alexander; Gasparini, Roberto; Bonanni, Paolo; Icardi, Giancarlo; Amicizia, Daniela; Arata, Lucia; Bragazzi, Nicola Luigi; Signori, Alessio; Landa, Paolo; Bechini, Angela; Boccalini, Sara

    2016-04-02

    Given the growing use and great potential of mobile apps, this project aimed to develop and implement a user-friendly app to increase laypeople's knowledge and awareness of invasive pneumococcal disease (IPD). Despite the heavy burden of IPD, the documented low awareness of IPD among both laypeople and healthcare professionals and far from optimal pneumococcal vaccination coverage, no app specifically targeting IPD has been developed so far. The app was designed to be maximally functional and conceived in accordance with user-centered design. Its content, layout and usability were discussed and formally tested during several workshops that involved the principal stakeholders, including experts in IPD and information technology and potential end-users. Following several workshops, it was decided that, in order to make the app more interactive, its core should be a personal "checker" of the risk of contracting IPD and a user-friendly risk-communication strategy. The checker was populated with risk factors identified through both Italian and international official guidelines. Formal evaluation of the app revealed its good readability and usability properties. A sister web site with the same content was created to achieve higher population exposure. Seven months after being launched in a price- and registration-free modality, the app, named "Pneumo Rischio," averaged 20.9 new users/day and 1.3 sessions/user. The first in-field results suggest that "Pneumo Rischio" is a promising tool for increasing the population's awareness of IPD and its prevention through a user-friendly risk checker.

  7. Crystallization and preliminary X-ray diffraction analysis of the Fab fragment of WO2, an antibody specific for the Aβ peptides associated with Alzheimer’s disease

    Energy Technology Data Exchange (ETDEWEB)

    Wun, Kwok S. [Biota Structural Biology Laboratory and Centre for Structural Neurobiology, St Vincent’s Institute of Medical Research, 41 Victoria Parade, Fitzroy, Victoria 3065 (Australia); Miles, Luke A. [Biota Structural Biology Laboratory and Centre for Structural Neurobiology, St Vincent’s Institute of Medical Research, 41 Victoria Parade, Fitzroy, Victoria 3065 (Australia); Department of Chemical and Biomolecular Engineering, The University of Melbourne, Victoria 3010 (Australia); Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, 30 Flemington Road, Parkville, Victoria 3010 (Australia); Crespi, Gabriela A. N. [Biota Structural Biology Laboratory and Centre for Structural Neurobiology, St Vincent’s Institute of Medical Research, 41 Victoria Parade, Fitzroy, Victoria 3065 (Australia); Wycherley, Kaye [WEHI Biotechnology Centre, La Trobe R& D Park, Bundoora, Victoria 3086 (Australia); Ascher, David B. [Biota Structural Biology Laboratory and Centre for Structural Neurobiology, St Vincent’s Institute of Medical Research, 41 Victoria Parade, Fitzroy, Victoria 3065 (Australia); Barnham, Kevin J.; Cappai, Roberto [Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, 30 Flemington Road, Parkville, Victoria 3010 (Australia); Department of Pathology, The University of Melbourne, Victoria 3010 (Australia); The Mental Health Research Institute of Victoria, Parkville, Victoria 3052 (Australia); Beyreuther, Konrad [ZMBH, University of Heidelberg, Heidelberg (Germany); Masters, Colin L. [Department of Pathology, The University of Melbourne, Victoria 3010 (Australia); The Mental Health Research Institute of Victoria, Parkville, Victoria 3052 (Australia); Parker, Michael W. [Biota Structural Biology Laboratory and Centre for Structural Neurobiology, St Vincent’s Institute of Medical Research, 41 Victoria Parade, Fitzroy, Victoria 3065 (Australia); Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, 30 Flemington Road, Parkville, Victoria 3010 (Australia); McKinstry, William J., E-mail: wjmckinstry@hotmail.com [Biota Structural Biology Laboratory and Centre for Structural Neurobiology, St Vincent’s Institute of Medical Research, 41 Victoria Parade, Fitzroy, Victoria 3065 (Australia); Department of Medicine (St Vincent’s Hospital), The University of Melbourne, 41 Victoria Parade, Fitzroy 3065 (Australia)

    2008-05-01

    Crystallization and X-ray diffraction data collection of the Fab fragment of the monoclonal antibody WO2 in the absence or presence of amyloid β peptides associated with Alzheimer’s disease are reported. The murine monoclonal antibody WO2 specifically binds the N-terminal region of the amyloid β peptide (Aβ) associated with Alzheimer’s disease. This region of Aβ has been shown to be the immunodominant B-cell epitope of the peptide and hence is considered to be a basis for the development of immunotherapeutic strategies against this prevalent cause of dementia. Structural studies have been undertaken in order to characterize the molecular basis for antibody recognition of this important epitope. Here, details of the crystallization and X-ray analysis of the Fab fragment of the unliganded WO2 antibody in two crystal forms and of the complexes that it forms with the truncated Aβ peptides Aβ{sub 1–16} and Aβ{sub 1–28} are presented. These crystals were all obtained using the hanging-drop vapour-diffusion method at 295 K. Crystals of WO2 Fab were grown in polyethylene glycol solutions containing ZnSO{sub 4}; they belonged to the orthorhombic space group P2{sub 1}2{sub 1}2{sub 1} and diffracted to 1.6 Å resolution. The complexes of WO2 Fab with either Aβ{sub 1–@}@{sub 16} or Aβ{sub 1–28} were cocrystallized from polyethylene glycol solutions. These two complex crystals grew in the same space group, P2{sub 1}2{sub 1}2{sub 1}, and diffracted to 1.6 Å resolution. A second crystal form of WO2 Fab was grown in the presence of the sparingly soluble Aβ{sub 1–42} in PEG 550 MME. This second form belonged to space group P2{sub 1} and diffracted to 1.9 Å resolution.

  8. Use of computerized tests to evaluate psychomotor performance in children with specific learning disabilities in comparison to normal children

    Directory of Open Access Journals (Sweden)

    Santosh Taur

    2014-01-01

    Full Text Available Background & objectives: Children with specific learning disabilities (SpLD have an unexplained difficulty in acquiring basic academic skills resulting in a significant discrepancy between their academic potential and achievements. This study was undertaken to compare the performance on a battery of six psychomotor tests of children with SpLD and those without any learning disabilities (controls using computerized tests. Methods: In this study, 25 children with SpLD and 25 controls (matched for age, socio-economic status and medium of instruction were given three training sessions over one week. Then children were asked to perform on the six computerized psychomotor tests. Results were compared between the two groups. Results: Children with SpLD fared significantly worse on finger tapping test, choice reaction test, digit picture substitution test and card sorting test compared to the controls ( p <0.05. Interpretation & conclusions: Children with SpLD have impairment of psychomotor skills like attention, sensory-motor coordination and executive functioning. Further research is needed to evaluate if the remedial education plan results in improvement in psychomotor performance of children with SpLD on these selected tests.

  9. Comparison of the Motor Performance and Vestibular Function in Infants with a Congenital Cytomegalovirus Infection or a Connexin 26 Mutation: A Preliminary Study.

    Science.gov (United States)

    Maes, Leen; De Kegel, Alexandra; Van Waelvelde, Hilde; De Leenheer, Els; Van Hoecke, Helen; Goderis, Julie; Dhooge, Ingeborg

    Hearing-impaired children are at risk for vestibular damage and delayed motor development. Two major causes of congenital hearing loss are cytomegalovirus (CMV) infection and connexin (Cx) 26 mutations. Comparison of the motor performance and vestibular function between these specific groups is still underexplored. The objective of this study was to investigate the impact of congenital (c)CMV and Cx26 on the motor performance and vestibular function in 6 months old infants. Forty children (mean age 6.7 months; range 4.8 to 8.9 months) participated in this cross-sectional design and were recruited from the Flemish CMV registry. They were divided into five age-matched groups: normal-hearing control, asymptomatic cCMV, normal-hearing symptomatic cCMV, hearing-impaired symptomatic cCMV, and hearing-impaired Cx26. Children were examined with the Peabody Developmental Motor Scales-2 and cervical vestibular-evoked myogenic potential (cVEMP) test. Symptomatic hearing-impaired cCMV children demonstrated a significantly lower gross motor performance compared with the control group (p = 0.005), the asymptomatic cCMV group (p = 0.034), and the Cx26 group (0.016). In this symptomatic hearing-impaired cCMV group, 4 out of 8 children had absent cVEMP responses that were related to the weakest gross motor performance. The Cx26 children showed no significant delay in motor development compared with the control children and none of these children had absent cVEMP responses. The weakest gross motor performance was found in symptomatic hearing-impaired cCMV-infected children with absent cVEMP responses. These results suggest that abnormal saccular responses are a major factor for this delayed motor development, although more work is needed including comprehensive vestibular function testing to verify this.

  10. Atividade física e desempenho em tarefas de funções executivas em idosos saudáveis: dados preliminares Physical activity and performance in executive function tasks in healthy older adults: preliminary data

    Directory of Open Access Journals (Sweden)

    Andreza Giuliane Guimarães Moreira

    2010-01-01

    of senior dance. After an initial triage, executive function tests were administered for all participants. RESULTS: Compared to the other groups, the DG presented better performance in the measures of planning (Tower of London and inhibitory control (Stroop test. DISCUSSION: The preliminary findings suggest a specificity of physical activity on the performance of some executive functions. Our perspective is to find the same results with a larger sample.

  11. Value of CT to predict surgically important bowel and/or mesenteric injury in blunt trauma: performance of a preliminary scoring system

    Energy Technology Data Exchange (ETDEWEB)

    Faget, Claire; Taourel, Patrice; Ruyer, Alban; Alili, Chakib; Millet, Ingrid [CHU Lapeyronie, Department of Medical Imaging, Montpellier (France); Charbit, Jonathan [CHU Lapeyronie, Department of Intensive Care and Anesthesiology, Montpellier (France); Molinari, Nicolas [UMR 729 MISTEA, CHU Montpellier, Department of Medical Information and Statistics, Montpellier (France)

    2015-12-15

    To evaluate the performance of a computed tomography (CT) diagnostic score to predict surgical treatment for blunt bowel and/or mesentery injury (BBMI) in consecutive abdominal trauma. This was a retrospective observational study of 805 consecutive abdominal traumas with 556 patients included and screened by an abdominal radiologist blinded to the patient outcome, to evaluate numerous CT findings and calculate their diagnostic performances. These CT findings were compared using univariate and multivariate analysis between patients who had a laparotomy-confirmed BBMI requiring surgical repair, and those without BBMI requiring surgery. A CT score was obtained with an internal bootstrap validation. Fifty-six patients (10.1 %) had BBMI requiring surgery. Nine CT signs were independently associated with BBMI requiring surgery and were used to develop a CT diagnostic score. The AUC of our model was 0.98 (95 % CI 0.96-100), with a ≥5 cut-off. Its diagnostic performance was determined by internal validation: sensitivity 91.1-100 %, specificity 85.7-97.6 %, positive predictive value 41.4-82.3 % and negative predictive value 98.9-100 %. Bowel wall discontinuity and mesenteric pneumoperitoneum had the strongest association with BBMI requiring surgery (OR = 128.9 and 140.5, respectively). We developed a reliable CT scoring system which is easy to implement and highly predictive of BBMI requiring surgery. (orig.)

  12. ANALYSIS OF THE INDICATORS SPECIFIC TO ENTITIES LISTED ON THE CAPITAL MARKET AND THEIR ROLE IN QUANTIFYING COMPANY PERFORMANCE

    Directory of Open Access Journals (Sweden)

    Maria Daniela BONDOC

    2014-06-01

    Full Text Available The paper aims at presenting certain indicators specific to entities listed on the capital market and their analysis based on the financial statements of C.N.T.E.E. Transelectrica S.A., listed on the Bucharest Stock Exchange: growth stock exchange indices (market capitalization, earnings per share, price to book ratio, price to sales ratio, price earnings ratio, cash EPS and dividend stock exchange ratios (dividend per share, dividend yield, and dividend payout ratio. The research methodology involved studying the financial statements of the entity for the 2009-2013 period. The case study method was used to study the evolution of the stock exchange indices and opinions were formulated concerning the performance reflected by the analysed indices.

  13. Benefits of deep encoding in Alzheimer disease. Analysis of performance on a memory task using the Item Specific Deficit Approach.

    Science.gov (United States)

    Oltra-Cucarella, J; Pérez-Elvira, R; Duque, P

    2014-06-01

    the aim of this study is to test the encoding deficit hypothesis in Alzheimer disease (AD) using a recent method for correcting memory tests. To this end, a Spanish-language adaptation of the Free and Cued Selective Reminding Test was interpreted using the Item Specific Deficit Approach (ISDA), which provides three indices: Encoding Deficit Index, Consolidation Deficit Index, and Retrieval Deficit Index. We compared the performances of 15 patients with AD and 20 healthy control subjects and analysed results using either the task instructions or the ISDA approach. patients with AD displayed deficient encoding of more than half the information, but items that were encoded properly could be retrieved later with the help of the same semantic clues provided individually during encoding. Virtually all the information retained over the long-term was retrieved by using semantic clues. Encoding was shown to be the most impaired process, followed by retrieval and consolidation. Discriminant function analyses showed that ISDA indices are more sensitive and specific for detecting memory impairments in AD than are raw scores. These results indicate that patients with AD present impaired information encoding, but they benefit from semantic hints that help them recover previously learned information. This should be taken into account for intervention techniques focusing on memory impairments in AD. Copyright © 2013 Sociedad Española de Neurología. Published by Elsevier Espana. All rights reserved.

  14. A Low-Cost GPS GSM/GPRS Telemetry System: Performance in Stationary Field Tests and Preliminary Data on Wild Otters (Lutra lutra)

    Science.gov (United States)

    Quaglietta, Lorenzo; Martins, Bruno Herlander; de Jongh, Addy; Mira, António; Boitani, Luigi

    2012-01-01

    Background Despite the increasing worldwide use of global positioning system (GPS) telemetry in wildlife research, it has never been tested on any freshwater diving animal or in the peculiar conditions of the riparian habitat, despite this latter being one of the most important habitat types for many animal taxa. Moreover, in most cases, the GPS devices used have been commercial and expensive, limiting their use in low-budget projects. Methodology/Principal Findings We have developed a low-cost, easily constructed GPS GSM/GPRS (Global System for Mobile Communications/General Packet Radio Service) and examined its performance in stationary tests, by assessing the influence of different habitat types, including the riparian, as well as water submersion and certain climatic and environmental variables on GPS fix-success rate and accuracy. We then tested the GPS on wild diving animals, applying it, for the first time, to an otter species (Lutra lutra). The rate of locations acquired during the stationary tests reached 63.2%, with an average location error of 8.94 m (SD = 8.55). GPS performance in riparian habitats was principally affected by water submersion and secondarily by GPS inclination and position within the riverbed. Temporal and spatial correlations of location estimates accounted for some variation in the data sets. GPS-tagged otters also provided accurate locations and an even higher GPS fix-success rate (68.2%). Conclusions/Significance Our results suggest that GPS telemetry is reliably applicable to riparian and even diving freshwater animals. They also highlight the need, in GPS wildlife studies, for performing site-specific pilot studies on GPS functioning as well as for taking into account eventual spatial and temporal correlation of location estimates. The limited price, small dimensions, and high performance of the device presented here make it a useful and cost-effective tool for studies on otters and other aquatic or terrestrial medium

  15. A low-cost GPS GSM/GPRS telemetry system: performance in stationary field tests and preliminary data on wild otters (Lutra lutra.

    Directory of Open Access Journals (Sweden)

    Lorenzo Quaglietta

    Full Text Available BACKGROUND: Despite the increasing worldwide use of global positioning system (GPS telemetry in wildlife research, it has never been tested on any freshwater diving animal or in the peculiar conditions of the riparian habitat, despite this latter being one of the most important habitat types for many animal taxa. Moreover, in most cases, the GPS devices used have been commercial and expensive, limiting their use in low-budget projects. METHODOLOGY/PRINCIPAL FINDINGS: We have developed a low-cost, easily constructed GPS GSM/GPRS (Global System for Mobile Communications/General Packet Radio Service and examined its performance in stationary tests, by assessing the influence of different habitat types, including the riparian, as well as water submersion and certain climatic and environmental variables on GPS fix-success rate and accuracy. We then tested the GPS on wild diving animals, applying it, for the first time, to an otter species (Lutra lutra. The rate of locations acquired during the stationary tests reached 63.2%, with an average location error of 8.94 m (SD = 8.55. GPS performance in riparian habitats was principally affected by water submersion and secondarily by GPS inclination and position within the riverbed. Temporal and spatial correlations of location estimates accounted for some variation in the data sets. GPS-tagged otters also provided accurate locations and an even higher GPS fix-success rate (68.2%. CONCLUSIONS/SIGNIFICANCE: Our results suggest that GPS telemetry is reliably applicable to riparian and even diving freshwater animals. They also highlight the need, in GPS wildlife studies, for performing site-specific pilot studies on GPS functioning as well as for taking into account eventual spatial and temporal correlation of location estimates. The limited price, small dimensions, and high performance of the device presented here make it a useful and cost-effective tool for studies on otters and other aquatic or

  16. The magnitude of muscular activation of four canine forelimb muscles in dogs performing two agility-specific tasks.

    Science.gov (United States)

    Cullen, Kimberley L; Dickey, James P; Brown, Stephen H M; Nykamp, Stephanie G; Bent, Leah R; Thomason, Jeffrey J; Moens, Noël M M

    2017-03-07

    The purpose of this study was to measure the muscular activation in four forelimb muscles while dogs performed agility tasks (i.e., jumping and A-frame) and to provide insight into potential relationships between level of muscular activation and risk of injury. Muscle activation in eight healthy, client-owned agility dogs was measured using ultrasound-guided fine-wire electromyography of four specific forelimb muscles: Biceps Brachii, Supraspinatus, Infraspinatus, and Triceps Brachii - Long Head, while dogs performed a two jump sequence and while dogs ascended and descended an A-frame obstacle at two different competition heights. The peak muscle activations during these agility tasks were between 1.7 and 10.6 fold greater than walking. Jumping required higher levels of muscle activation compared to ascending and descending an A-frame, for all muscles of interest. There was no significant difference in muscle activation between the two A-frame heights. Compared to walking, all of the muscles were activated at high levels during the agility tasks and our findings indicate that jumping is an especially demanding activity for dogs in agility. This information is broadly relevant to understanding the pathophysiology of forelimb injuries related to canine athletic activity.

  17. Task-Specific Motor Rehabilitation Therapy After Stroke Improves Performance in a Different Motor Task: Translational Evidence.

    Science.gov (United States)

    El Amki, M; Baumgartner, P; Bracko, O; Luft, A R; Wegener, S

    2017-01-14

    While the stroke survivor with a motor deficit strives for recovery of all aspects of daily life movements, neurorehabilitation training is often task specific and does not generalize to movements other than the ones trained. In rodent models of post-stroke recovery, this problem is poorly investigated as the training task is often the same as the one that measures motor function. The present study investigated whether motor training by pellet reaching translates into enhancement of different motor functions in rats after stroke. Adult rats were subjected to 60-min middle cerebral artery occlusion (MCAO). Five days after stroke, animals received either training consisting of 7 days of pellet reaching with the affected forelimb (n = 18) or no training (n = 18). Sensorimotor deficits were assessed using the sticky tape test and a composite neuroscore. Infarct volumes were measured by T2-weighted MRI on day 28. Both groups of rats showed similar lesion volume and forelimb impairment after stroke. Trained animals improved in the sticky tape test after day 7 post-stroke reaching peak performance on day 14. More reaching attempts during rehabilitation were associated with a better performance in the sticky tape removal time. Task-oriented motor training generalizes to other motor functions after experimental stroke. Training intensity correlates with recovery.

  18. Regional brain amyloid-β accumulation associates with domain-specific cognitive performance in Parkinson disease without dementia.

    Science.gov (United States)

    Akhtar, Rizwan S; Xie, Sharon X; Chen, Yin J; Rick, Jacqueline; Gross, Rachel G; Nasrallah, Ilya M; Van Deerlin, Vivianna M; Trojanowski, John Q; Chen-Plotkin, Alice S; Hurtig, Howard I; Siderowf, Andrew D; Dubroff, Jacob G; Weintraub, Daniel

    2017-01-01

    Parkinson disease patients develop clinically significant cognitive impairment at variable times over their disease course, which is often preceded by milder deficits in memory, visuo-spatial, and executive domains. The significance of amyloid-β accumulation to these problems is unclear. We hypothesized that amyloid-β PET imaging by 18F-florbetapir, a radiotracer that detects fibrillar amyloid-β plaque deposits, would identify subjects with global cognitive impairment or poor performance in individual cognitive domains in non-demented Parkinson disease patients. We assessed 61 non-demented Parkinson disease patients with detailed cognitive assessments and 18F-florbetapir PET brain imaging. Scans were interpreted qualitatively (positive or negative) by two independent nuclear medicine physicians blinded to clinical data, and quantitatively by a novel volume-weighted method. The presence of mild cognitive impairment was determined through an expert consensus process using Level 1 criteria from the Movement Disorder Society. Nineteen participants (31.2%) were diagnosed with mild cognitive impairment and the remainder had normal cognition. Qualitative 18F-florbetapir PET imaging was positive in 15 participants (24.6%). Increasing age and presence of an APOE ε4 allele were associated with higher composite 18F-florbetapir binding. In multivariable models, an abnormal 18F-florbetapir scan by expert rating was not associated with a diagnosis of mild cognitive impairment. However, 18F-florbetapir retention values in the posterior cingulate gyrus inversely correlated with verbal memory performance. Retention values in the frontal cortex, precuneus, and anterior cingulate gyrus retention values inversely correlated with naming performance. Regional cortical amyloid-β amyloid, as measured by 18F-florbetapir PET, may be a biomarker of specific cognitive deficits in non-demented Parkinson disease patients.

  19. Analytical performance specifications for changes in assay bias (Δbias) for data with logarithmic distributions as assessed by effects on reference change values

    DEFF Research Database (Denmark)

    Hyltoft Petersen, Per; Lund, Flemming; Fraser, Callum G;

    2016-01-01

    BACKGROUND: The distributions of within-subject biological variation are usually described as coefficients of variation, as are analytical performance specifications for bias, imprecision and other characteristics. Estimation of specifications required for reference change values is traditionally...... performance specifications for reference change value, with combination of Δbias and CVA based on log-Gaussian distributions of CVI as natural logarithms. The model was tested using plasma prolactin and glucose as examples. RESULTS: Analytical performance specifications for reference change value generated...... using the new model based on log-Gaussian distributions were practically identical with the traditional model based on Gaussian distributions. CONCLUSION: The traditional and simple to apply model used to generate analytical performance specifications for reference change value, based on the use...

  20. Altered behavioral performance and live imaging of circuit-specific neural deficiencies in a zebrafish model for psychomotor retardation.

    Directory of Open Access Journals (Sweden)

    David Zada

    2014-09-01

    Full Text Available The mechanisms and treatment of psychomotor retardation, which includes motor and cognitive impairment, are indefinite. The Allan-Herndon-Dudley syndrome (AHDS is an X-linked psychomotor retardation characterized by delayed development, severe intellectual disability, muscle hypotonia, and spastic paraplegia, in combination with disturbed thyroid hormone (TH parameters. AHDS has been associated with mutations in the monocarboxylate transporter 8 (mct8/slc16a2 gene, which is a TH transporter. In order to determine the pathophysiological mechanisms of AHDS, MCT8 knockout mice were intensively studied. Although these mice faithfully replicated the abnormal serum TH levels, they failed to exhibit the neurological and behavioral symptoms of AHDS patients. Here, we generated an mct8 mutant (mct8-/- zebrafish using zinc-finger nuclease (ZFN-mediated targeted gene editing system. The elimination of MCT8 decreased the expression levels of TH receptors; however, it did not affect the expression of other TH-related genes. Similar to human patients, mct8-/- larvae exhibited neurological and behavioral deficiencies. High-throughput behavioral assays demonstrated that mct8-/- larvae exhibited reduced locomotor activity, altered response to external light and dark transitions and an increase in sleep time. These deficiencies in behavioral performance were associated with altered expression of myelin-related genes and neuron-specific deficiencies in circuit formation. Time-lapse imaging of single-axon arbors and synapses in live mct8-/- larvae revealed a reduction in filopodia dynamics and axon branching in sensory neurons and decreased synaptic density in motor neurons. These phenotypes enable assessment of the therapeutic potential of three TH analogs that can enter the cells in the absence of MCT8. The TH analogs restored the myelin and axon outgrowth deficiencies in mct8-/- larvae. These findings suggest a mechanism by which MCT8 regulates neural circuit

  1. The Kjeldahl method as a primary reference procedure for total protein in certified reference materials used in clinical chemistry. II. Selection of direct Kjeldahl analysis and its preliminary performance parameters.

    Science.gov (United States)

    Vinklárková, Bára; Chromý, Vratislav; Šprongl, Luděk; Bittová, Miroslava; Rikanová, Milena; Ohnútková, Ivana; Žaludová, Lenka

    2015-01-01

    To select a Kjeldahl procedure suitable for the determination of total protein in reference materials used in laboratory medicine, we reviewed in our previous article Kjeldahl methods adopted by clinical chemistry and found an indirect two-step analysis by total Kjeldahl nitrogen corrected for its nonprotein nitrogen and a direct analysis made on isolated protein precipitates. In this article, we compare both procedures on various reference materials. An indirect Kjeldahl method gave falsely lower results than a direct analysis. Preliminary performance parameters qualify the direct Kjeldahl analysis as a suitable primary reference procedure for the certification of total protein in reference laboratories.

  2. Environmental Survey preliminary report

    Energy Technology Data Exchange (ETDEWEB)

    1988-04-01

    This report presents the preliminary findings from the first phase of the Environmental Survey of the United States Department of Energy (DOE) Sandia National Laboratories conducted August 17 through September 4, 1987. The objective of the Survey is to identify environmental problems and areas of environmental risk associated with Sandia National Laboratories-Albuquerque (SNLA). The Survey covers all environmental media and all areas of environmental regulation. It is being performed in accordance with the DOE Environmental Survey Manual. This phase of the Survey involves the review of existing site environmental data, observations of the operations carried on at SNLA, and interviews with site personnel. 85 refs., 49 figs., 48 tabs.

  3. Site-specific carbon deposition for hierarchically ordered core/shell-structured graphitic carbon with remarkable electrochemical performance.

    Science.gov (United States)

    Lv, Yingying; Wu, Zhangxiong; Qian, Xufang; Fang, Yin; Feng, Dan; Xia, Yongyao; Tu, Bo; Zhao, Dongyuan

    2013-10-01

    A fascinating core-shell-structured graphitic carbon material composed of ordered microporous core and uniform mesoporous shell is fabricated for the first time through a site-specific chemical vapor deposition process by using a nanozeolite@mesostructured silica composite molecular sieve as the template. The mesostructure-directing agent cetyltrimethylammonium bromide in the shell of the template can be either burned off or carbonized so that it is successfully utilized as a pore switch to turn the shell of the template "on" or "off" to allow selective carbon deposition. The preferred carbon deposition process can be performed only in the inner microporous zeolite cores or just within the outer mesoporous shells, resulting in a zeolite-like ordered microporous carbon or a hollow mesoporous carbon. Full carbon deposition in the template leads to the new core-shell-structured microporous@mesoporous carbon with a nanographene-constructed framework for fast electron transport, a microporous nanocore with large surface area for high-capacity storage of lithium ions, a mesoporous shell with highly opened mesopores as a transport layer for lithium ions and electron channels to access inner cores. The ordered micropores are protected by the mesoporous shell, avoiding pore blockage as the formation of solid electrolyte interphase layers. Such a unique core-shell-structured microporous@mesoporous carbon material represents a newly established lithium ion storage model, demonstrating high reversible energy storage, excellent rate capability, and long cyclic stability.

  4. The mannose-specific lectin domains of Flo1p from Saccharomyces cerevisiae and Lg-Flo1p from S. pastorianus: crystallization and preliminary X-ray diffraction analysis of the adhesin-carbohydrate complexes.

    Science.gov (United States)

    Ielasi, Francesco S; Goyal, Parveen; Sleutel, Mike; Wohlkonig, Alexandre; Willaert, Ronnie G

    2013-07-01

    Flo1p and Lg-Flo1p are two cell-wall adhesins belonging to the Flo (flocculation) protein family from the yeasts Saccharomyces cerevisiae and S. pastorianus. The main function of these modular proteins endowed with calcium-dependent lectin activity is to mediate cell-cell adhesion events during yeast flocculation, a process which is well known at the cellular level but still not fully characterized from a molecular perspective. Recently, structural features of the N-terminal Flo lectin domains, including the N-terminal domain of Lg-Flo1p (N-Lg-Flo1p), and their interactions with carbohydrate molecules have been investigated. However, structural data concerning the N-terminal domain of Flo1p (N-Flo1p), which is the most specific among the Flo proteins, are missing and information about the N-Lg-Flo1p-carbohydrate interaction still lacks detailed structural insight. Here, the crystallization and preliminary X-ray characterization of the apo form and the mannose complex of N-Flo1p and X-ray analysis of N-Lg-Flo1p crystals soaked in α-1,2-mannobiose are reported. The N-Flo1p crystals diffracted to a resolution of 1.43 Å in the case of the apo form and to 2.12 Å resolution for the mannose complex. Both crystals were orthorhombic and belonged to space group P212121, with one molecule in the asymmetric unit. The N-Lg-Flo1p-α-1,2-mannobiose complex crystal diffracted to 1.73 Å resolution and belonged to the monoclinic space group P1211 with two molecules in the asymmetric unit.

  5. Ecologically Valid Carbohydrate Intake during Soccer-Specific Exercise Does Not Affect Running Performance in a Fed State

    Directory of Open Access Journals (Sweden)

    Mark P. Funnell

    2017-01-01

    Full Text Available This study assessed the effect of carbohydrate intake on self-selected soccer-specific running performance. Sixteen male soccer players (age 23 ± 4 years; body mass 76.9 ± 7.2 kg; predicted VO2max = 54.2 ± 2.9 mL∙kg−1∙min−1; soccer experience 13 ± 4 years completed a progressive multistage fitness test, familiarisation trial and two experimental trials, involving a modified version of the Loughborough Intermittent Shuttle Test (LIST to simulate a soccer match in a fed state. Subjects completed six 15 min blocks (two halves of 45 min of intermittent shuttle running, with a 15-min half-time. Blocks 3 and 6, allowed self-selection of running speeds and sprint times, were assessed throughout. Subjects consumed 250 mL of either a 12% carbohydrate solution (CHO or a non-caloric taste matched placebo (PLA before and at half-time of the LIST. Sprint times were not different between trials (CHO 2.71 ± 0.15 s, PLA 2.70 ± 0.14 s; p = 0.202. Total distance covered in self-selected blocks (block 3: CHO 2.07 ± 0.06 km; PLA 2.09 ± 0.08 km; block 6: CHO 2.04 ± 0.09 km; PLA 2.06 ± 0.08 km; p = 0.122 was not different between trials. There was no difference between trials for distance covered (p ≥ 0.297 or mean speed (p ≥ 0.172 for jogging or cruising. Blood glucose concentration was greater (p < 0.001 at the end of half-time during the CHO trial. In conclusion, consumption of 250 mL of 12% CHO solution before and at half-time of a simulated soccer match does not affect self-selected running or sprint performance in a fed state.

  6. Ecologically Valid Carbohydrate Intake during Soccer-Specific Exercise Does Not Affect Running Performance in a Fed State

    Science.gov (United States)

    Funnell, Mark P.; Dykes, Nick R.; Owen, Elliot J.; Mears, Stephen A.; Rollo, Ian; James, Lewis J.

    2017-01-01

    This study assessed the effect of carbohydrate intake on self-selected soccer-specific running performance. Sixteen male soccer players (age 23 ± 4 years; body mass 76.9 ± 7.2 kg; predicted VO2max = 54.2 ± 2.9 mL∙kg−1∙min−1; soccer experience 13 ± 4 years) completed a progressive multistage fitness test, familiarisation trial and two experimental trials, involving a modified version of the Loughborough Intermittent Shuttle Test (LIST) to simulate a soccer match in a fed state. Subjects completed six 15 min blocks (two halves of 45 min) of intermittent shuttle running, with a 15-min half-time. Blocks 3 and 6, allowed self-selection of running speeds and sprint times, were assessed throughout. Subjects consumed 250 mL of either a 12% carbohydrate solution (CHO) or a non-caloric taste matched placebo (PLA) before and at half-time of the LIST. Sprint times were not different between trials (CHO 2.71 ± 0.15 s, PLA 2.70 ± 0.14 s; p = 0.202). Total distance covered in self-selected blocks (block 3: CHO 2.07 ± 0.06 km; PLA 2.09 ± 0.08 km; block 6: CHO 2.04 ± 0.09 km; PLA 2.06 ± 0.08 km; p = 0.122) was not different between trials. There was no difference between trials for distance covered (p ≥ 0.297) or mean speed (p ≥ 0.172) for jogging or cruising. Blood glucose concentration was greater (p < 0.001) at the end of half-time during the CHO trial. In conclusion, consumption of 250 mL of 12% CHO solution before and at half-time of a simulated soccer match does not affect self-selected running or sprint performance in a fed state. PMID:28067762

  7. Risk assessment of transgenic apomictic tetraploid bahiagrass, cytogenetics, breeding behavior and performance of intra-specific hybrids.

    Science.gov (United States)

    Sandhu, Sukhpreet; James, Victoria A; Quesenberry, Kenneth H; Altpeter, Fredy

    2009-11-01

    Pollen-mediated gene transfer from stress tolerant or herbicide-resistant transgenic plants may cause environmental or agronomic problems. Apomictic seed production found in some bahiagrass cultivars may serve as a natural transgene containment system. Under greenhouse conditions, the average gene transfer frequency from an herbicide-resistant apomictic tetraploid to a population of sexual diploid bahiagrass genotypes or apomictic tetraploid bahiagrass was 0.16% when the transgenic pollen donor was placed at 0.5-1.5 m distance from the non-transgenic pollen receptors. The herbicide-resistant hybrids were characterized for transgene integration, expression and ploidy, by Southern blot analysis, immuno-chromatography and flow cytometry, respectively. Hybrids resulting from open pollination of non-transgenic diploid female plants with transgenic tetraploid male plants were triploids or near-triploids, with 2n = 26-34. These hybrids displayed a wide range of phenotypic variability, including some non-persistent or non-flowering dwarf-type hybrids with good vigor, or hybrids with vegetative growth similar to non-transgenic plants, but with significantly reduced seed set. Non-flowering aneu-triploids with good vigor/field performance will provide the highest level of transgene containment. Embryo sac analysis of pollinated spikelets confirmed a high proportion of aborted ovules. An apospory-linked RFLP marker was detected in 13 of the 15 near-triploid hybrids. All flowering aneuploid hybrids displayed significantly reduced seed set, and none of the sexual near-triploid hybrids produced any seeds. All tetraploid gene transfer events carried the apospory-linked RFLP marker, suggesting that despite the presence of the aposporus locus, a low degree of sexuality co-exists in apomictic tetraploid cultivars. Thus, tetraploid apomictic bahiagrass does not provide complete transgene containment, although intra-specific gene transfer is drastically reduced compared to sexually

  8. PERFORMANCE

    Directory of Open Access Journals (Sweden)

    M Cilli

    2014-10-01

    Full Text Available This study aimed to investigate the kinematic and kinetic changes when resistance is applied in horizontal and vertical directions, produced by using different percentages of body weight, caused by jumping movements during a dynamic warm-up. The group of subjects consisted of 35 voluntary male athletes (19 basketball and 16 volleyball players; age: 23.4 ± 1.4 years, training experience: 9.6 ± 2.7 years; height: 177.2 ± 5.7 cm, body weight: 69.9 ± 6.9 kg studying Physical Education, who had a jump training background and who were training for 2 hours, on 4 days in a week. A dynamic warm-up protocol containing seven specific resistance movements with specific resistance corresponding to different percentages of body weight (2%, 4%, 6%, 8%, 10% was applied randomly on non consecutive days. Effects of different warm-up protocols were assessed by pre-/post- exercise changes in jump height in the countermovement jump (CMJ and the squat jump (SJ measured using a force platform and changes in hip and knee joint angles at the end of the eccentric phase measured using a video camera. A significant increase in jump height was observed in the dynamic resistance warm-up conducted with different percentages of body weight (p 0.05. In jump movements before and after the warm-up, while no significant difference between the vertical ground reaction forces applied by athletes was observed (p>0.05, in some cases of resistance, a significant reduction was observed in hip and knee joint angles (p<0.05. The dynamic resistance warm-up method was found to cause changes in the kinematics of jumping movements, as well as an increase in jump height values. As a result, dynamic warm-up exercises could be applicable in cases of resistance corresponding to 6-10% of body weight applied in horizontal and vertical directions in order to increase the jump performance acutely.

  9. Positive Effects of Specific Exercise and Novel Turning-based Treadmill Training on Turning Performance in Individuals with Parkinson’s disease: A Randomized Controlled Trial

    Science.gov (United States)

    Cheng, Fang-Yu; Yang, Yea-Ru; Chen, Li-Mei; Wu, Yih-Ru; Cheng, Shih-Jung; Wang, Ray-Yau

    2016-01-01

    Two different training strategies to improve turning performance in individuals with Parkinson’s disease (PD) were designed and investigated in this study. Subjects were randomly assigned to a specific exercise group, turning-based training group, or control group to receive training that emphasized balance and strengthening, turning-based treadmill training, and general exercise training, respectively. A total of 12 30-min training sessions followed by 10 min of turning training on a level surface were administered over 4 to 6 weeks. The results (n = 12 for each group) showed that both the specific exercise and turning-based training group experienced improved turning performance, the primary outcome, compared with the control group (specific exercise, 33% change, p = 0.016; turning-based training, 35% change, p = 0.021). For the secondary outcomes, the specific exercise group performed better than the control group on the Tinetti balance scale, limit of stability test and lower extremity extensor and abductor strength. The turning-based training groups performed better than the control group in sensory organization and ankle plantar flexor strength. In summary, specific exercise training and turning-based treadmill training were both effective in improving turning performance in participants with PD. However, the improvements in turning performance of these two groups resulted from improving different aspects of impairment in individuals with PD. PMID:27628128

  10. Preliminary AD-Horn Thermomechanical and Electrodynamic Simulations

    CERN Document Server

    AUTHOR|(CDS)2095747; Horvath, David; Calviani, Marco

    2016-01-01

    As part of the Antiproton Decelerator (AD) target area consolidation activities planned for LS2, it has been necessary to perform a comprehensive study of the thermo-structural behaviour of the AD magnetic horn during operation, in order to detail specific requirements for the upgrade projects and testing procedures. The present work illustrates the preliminary results of the finite element analysis carried out to evaluate the thermal and structural behaviour of the device, as well as the methodology used to model and solve the thermomechanical and electrodynamic simulations performed in the AD magnetic horn.

  11. Preliminary Design of a LSA Aircraft Using Wind Tunnel Tests

    Directory of Open Access Journals (Sweden)

    Norbert ANGI

    2015-12-01

    Full Text Available This paper presents preliminary results concerning the design and aerodynamic calculations of a light sport aircraft (LSA. These were performed for a new lightweight, low cost, low fuel consumption and long-range aircraft. The design process was based on specific software tools as Advanced Aircraft Analysis (AAA, XFlr 5 aerodynamic and dynamic stability analysis, and Catia design, according to CS-LSA requirements. The calculations were accomplished by a series of tests performed in the wind tunnel in order to assess experimentally the aerodynamic characteristics of the airplane.

  12. Preliminary Monthly Climatological Summaries

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Preliminary Local Climatological Data, recorded since 1970 on Weather Burean Form 1030 and then National Weather Service Form F-6. The preliminary climate data pages...

  13. Case Specificity of Standardized-Patient Examinations: Consistency of Performance on Components of Clinical Competence within and between Cases.

    Science.gov (United States)

    Colliver, Jerry A.; And Others

    1990-01-01

    Standardized patient case problems were administered to approximately 280 final year medical students. Results indicate that performance on a given component of clinical competence shows less consistency when measured on different cases than does performance on different components measured on the same case. (TJH)

  14. The effect of rater training on scoring performance and scale-specific expertise amongst occupational therapists participating in a multicentre study

    DEFF Research Database (Denmark)

    Hansen, Tina; Elholm Madsen, Esben; Sørensen, Annette

    2016-01-01

    pre- to post-training using percentage exact agreement (PA) of scored MISA items of a case-vignette and a Likert scale self-report of scale-specific expertise. RESULTS: PA increased significantly from pre- to post-training (Z = -4.404, p ... of the training on scoring performance and scale-specific expertise amongst raters. METHOD: During 2 days of rater training, 81 occupational therapists (OTs) were qualified to observe and score dysphagic clients' mealtime performance according to the criteria of 36 MISA-items. The training effects were evaluated...... deficient mealtime performance appeared most difficult to score. The OTs scale-specific expertise improved significantly (knowledge: Z = -7.857, p

  15. Multistation alarm system for eruptive activity based on the automatic classification of volcanic tremor: specifications and performance

    Science.gov (United States)

    Langer, Horst; Falsaperla, Susanna; Messina, Alfio; Spampinato, Salvatore

    2015-04-01

    With over fifty eruptive episodes (Strombolian activity, lava fountains, and lava flows) between 2006 and 2013, Mt Etna, Italy, underscored its role as the most active volcano in Europe. Seven paroxysmal lava fountains at the South East Crater occurred in 2007-2008 and 46 at the New South East Crater between 2011 and 2013. Month-lasting lava emissions affected the upper eastern flank of the volcano in 2006 and 2008-2009. On this background, effective monitoring and forecast of volcanic phenomena are a first order issue for their potential socio-economic impact in a densely populated region like the town of Catania and its surroundings. For example, explosive activity has often formed thick ash clouds with widespread tephra fall able to disrupt the air traffic, as well as to cause severe problems at infrastructures, such as highways and roads. For timely information on changes in the state of the volcano and possible onset of dangerous eruptive phenomena, the analysis of the continuous background seismic signal, the so-called volcanic tremor, turned out of paramount importance. Changes in the state of the volcano as well as in its eruptive style are usually concurrent with variations of the spectral characteristics (amplitude and frequency content) of tremor. The huge amount of digital data continuously acquired by INGV's broadband seismic stations every day makes a manual analysis difficult, and techniques of automatic classification of the tremor signal are therefore applied. The application of unsupervised classification techniques to the tremor data revealed significant changes well before the onset of the eruptive episodes. This evidence led to the development of specific software packages related to real-time processing of the tremor data. The operational characteristics of these tools - fail-safe, robustness with respect to noise and data outages, as well as computational efficiency - allowed the identification of criteria for automatic alarm flagging. The

  16. Effects of time-of-day on neuromuscular function in untrained men: Specific responses of high morning performers and high evening performers.

    Science.gov (United States)

    Küüsmaa, Maria; Sedliak, Milan; Häkkinen, Keijo

    2015-01-01

    It has been clearly established that maximal force varies during the day in human muscles but the exact mechanisms behind the diurnal rhythms are still not fully clarified. Therefore, the aim of this study was to examine the diurnal rhythms in maximal isometric force production in a large group of participants and also by separating the high morning performance types (n = 8) and the high evening performance types (n = 19) from the neutral types (n = 45) based on their actual maximal isometric force levels. Measurements were performed in the morning (7:26 h ± 63 min) and in the evening (17:57 h ± 74 min) for maximal bilateral isometric leg press force (MVCLP) together with myoelectric activity (EMGLP), maximal unilateral isometric knee extension force (MVCKE) and maximal voluntary activation level (VA%) during maximal unilateral isometric knee extension force (MVCVA) together with myoelectric activity (EMGVA). In addition, venous blood samples were drawn four times a day and serum testosterone and cortisol concentrations were analyzed. None of the participants belonged to the extreme morning or evening chronotype according to the Munich Chronotype Questionnaire. In the total group of participants, MVCLP and MVCKE were 4.4 ± 12.9% (p variation. The high morning performance types showed lower force values in the evening compared to the morning for MVCLP (10.8 ± 9.1%; p variation was observed for MVCVA and VA%. The high evening performance types showed higher force values in the evening for MVCLP (16.1 ± 15.9%; p variations. EMGLP and EMGVA did not show significant diurnal fluctuations in any group. Serum testosterone and cortisol concentrations showed normal daily rhythms with higher values observed in the morning in all of the groups (p explain the diurnal fluctuations in maximal strength performance, but peripheral mechanisms were also possibly involved.

  17. A simple and specific high performance liquid chromatography method for the assay of a series of novel dermal penetration enhancers.

    Science.gov (United States)

    Michniak, B B; Seyda, K L

    1993-02-01

    Synopsis A series of clofibric acid amides has been synthesized and previously reported by the authors as possessing enhancer activity in vitro in athymic nude mouse skin against model drugs, hydrocortisone-21-acetate and beta-methasone-17-valerate. An assay was required for each of these enhancers however, which would be specific for each compound and would also separate model drugs and their metabolite peaks. This study reports reverse phase high performance liquid chromatography assays for clofibric acid amide and seven derivatives (Ia-Ig). All enhancers showed maximum absorption at 232 nm, betamethasone (BM) and its valerate (BMV) at 238 nm, and hydrocortisone (HC) and its acetate (HCA) at 242 nm. Practical units of detection for the amides were 0.46-2.8 mug ml(-1) and peaks were sharp and well-separated from steroid peaks in three vehicles - methanol alone. Franz diffusion cell receptor phase samples (isotonic phosphate buffer), and full-thickness athymic nude mouse skin extracts in methanol. Mobile phases consisted of various proportions of acetonitrile and water, some with 2-propanol. The octyl amide for example, with mobile phase CH(3)CN: H(2)O (85:15) at 1 ml min(-1) had a retention time (t(R)) of 7.9 mins. Under the same conditions, retention times for the steroids were HC, t(R)= 3.3 mins; HCA, t(R)= 4.3 mins; BM, t(R)= 3.4 mins; BMV, t(R)= 4.6 mins. Résumé Les auteurs avaient démontré dans un article précédent le pouvoir accélérateur de pénétration dermique in vitro d'une gamme d'amides d'acide clofibrique sur la peau de souris sans poils, et sans thymus avec des médicaments types tels que l'acetate 21 d'hydrocortisone et le valerate 17 de beta-metasone. Il a cependant été requis, pour chacun de ces accélérateurs, un test spécifique pour chaque composition, permettant de séparer chaque médicament et les pics des métabolites. Cette étude décrit des tests par chromatographie liquide à haute performance en phase inverse pour l

  18. Performance and specific emissions contours throughout the operating range of hydrogen-fueled compression ignition engine with diesel and RME pilot fuels

    Directory of Open Access Journals (Sweden)

    Shahid Imran

    2015-09-01

    Full Text Available This paper presents the performance and emissions contours of a hydrogen dual fueled compression ignition (CI engine with two pilot fuels (diesel and rapeseed methyl ester, and compares the performance and emissions iso-contours of diesel and rapeseed methyl ester (RME single fueling with diesel and RME piloted hydrogen dual fueling throughout the engines operating speed and power range. The collected data have been used to produce iso-contours of thermal efficiency, volumetric efficiency, specific oxides of nitrogen (NOX, specific hydrocarbons (HC and specific carbon dioxide (CO2 on a power-speed plane. The performance and emission maps are experimentally investigated, compared, and critically discussed. Apart from medium loads at lower and medium speeds with diesel piloted hydrogen combustion, dual fueling produced lower thermal efficiency everywhere across the map. For diesel and RME single fueling the maximum specific NOX emissions are centered at the mid speed, mid power region. Hydrogen dual fueling produced higher specific NOX with both pilot fuels as compared to their respective single fueling operations. The range, location and trends of specific NOX varied significantly when compared to single fueling cases. The volumetric efficiency is discussed in detail with the implications of manifold injection of hydrogen analyzed with the conclusions drawn.

  19. Trade-off results and preliminary designs of Near-Term Hybrid Vehicles

    Science.gov (United States)

    Sandberg, J. J.

    1980-01-01

    Phase I of the Near-Term Hybrid Vehicle Program involved the development of preliminary designs of electric/heat engine hybrid passenger vehicles. The preliminary designs were developed on the basis of mission analysis, performance specification, and design trade-off studies conducted independently by four contractors. THe resulting designs involve parallel hybrid (heat engine/electric) propulsion systems with significant variation in component selection, power train layout, and control strategy. Each of the four designs is projected by its developer as having the potential to substitute electrical energy for 40% to 70% of the petroleum fuel consumed annually by its conventional counterpart.

  20. Performance-based specifications and control of concrete durability state-of-the-art report RILEM TC 230-PSC

    CERN Document Server

    Luco, Luis

    2016-01-01

    This work gives an overview of significant research from recent years concerning performance-based design and quality control for concrete durability and its implementation. In engineering practice, performance approaches are often still used in combination with prescriptive requirements. This is largely because, for most durability test methods, sufficient practical experience still has to be gained before engineers and owners are prepared to fully rely on them.   This book, compiled by RILEM TC 230-PSC, is intended to assist efforts to successfully build the foundation for the full implementation of performance-based approaches through the exchange of relevant knowledge and experience between researchers and practitioners worldwide.  .

  1. A comparison of student performance on discipline-specific versus integrated exams in a medical school course

    National Research Council Canada - National Science Library

    Andrew R. Thompson; Mark W. Braun; Valerie D. O'Loughlin

    2013-01-01

    .... This study examined how a shift from discipline-focused instruction and assessment to integrated instruction and assessment affected student performance in a second-year medical school pathology course...

  2. The Effects of Music and Movement Opportunity on the Analogical Reasoning Performance of African American and White School Children: A Preliminary Study.

    Science.gov (United States)

    Allen, Brenda A.; Butler, Lisa

    1996-01-01

    Studies contextual factors informed by cultural experiences and their influence on learning task performance in 15 African American and 13 white children. The African American children performed better when allowed to coordinate movement and music to the learning task while white students had the opposite results. (GR)

  3. The Effect of Picture Task Cards on Performance of the Test of Gross Motor Development by Preschool-Aged Children: A Preliminary Study

    Science.gov (United States)

    Breslin, Casey M.; Robinson, Leah E.; Rudisill, Mary E.

    2013-01-01

    Performance on the Test of Gross Motor Development (Second Edition; TGMD-2) by children with autism spectrum disorders improves when picture task cards were implemented into the assessment protocol [Breslin, C.M., & Rudisill, M.E. (2011). "The effect of visual supports on performance of the TGMD-2 for children with autism spectrum…

  4. The Effect of Picture Task Cards on Performance of the Test of Gross Motor Development by Preschool-Aged Children: A Preliminary Study

    Science.gov (United States)

    Breslin, Casey M.; Robinson, Leah E.; Rudisill, Mary E.

    2013-01-01

    Performance on the Test of Gross Motor Development (Second Edition; TGMD-2) by children with autism spectrum disorders improves when picture task cards were implemented into the assessment protocol [Breslin, C.M., & Rudisill, M.E. (2011). "The effect of visual supports on performance of the TGMD-2 for children with autism spectrum disorder."…

  5. Autoantibodies to citrullinated proteins in rheumatoid arthritis: clinical performance and biochemical aspects of an RA-specific marker.

    NARCIS (Netherlands)

    Nijenhuis, S.; Zendman, A.J.W.; Vossenaar, E.R.; Pruijn, G.J.M.; Venrooij, W.J.W. van

    2004-01-01

    Rheumatoid arthritis (RA) is a common, systemic autoimmune disease of which the exact etiology is not known. In the past 10 years, substantial progress has been made in the identification of the antigens specifically recognized by the autoantibodies of RA patients. A central factor in this respect i

  6. Performance Assessment of Counseling Skills Based on Specific Theories: Acquisition, Retention and Transfer to Actual Counseling Sessions

    Science.gov (United States)

    Schaefle, Scott; Smaby, Marlowe H.; Packman, Jill; Maddux, Cleborne D.

    2007-01-01

    The purposes of the present study were to determine if (a) students trained to demonstrate specific skills learn these skills and transfer them to actual counseling sessions; (b) mastery of counseling skills differs by students' adherence to one of four general counseling theories; (c) mastery of counseling skills is related to counseling goal…

  7. Religion and Action Control: Faith-Specific Modulation of the Simon Effect but Not Stop-Signal Performance

    Science.gov (United States)

    Hommel, Bernhard; Colzato, Lorenza S.; Scorolli, Claudia; Borghi, Anna M.; van den Wildenberg, Wery P. M.

    2011-01-01

    Previous findings suggest that religion has a specific impact on attentional processes. Here we show that religion also affects action control. Experiment 1 compared Dutch Calvinists and Dutch atheists, matched for age, sex, intelligence, education, and cultural and socio-economic background, and Experiment 2 compared Italian Catholics with…

  8. Religion and action control: faith-specific modulation of the Simon effect but not stop-signal performance

    NARCIS (Netherlands)

    Hommel, B.; Colzato, L.S.; Scorolli, C.; Borghi, A.M.; van den Wildenberg, W.P.M.

    2011-01-01

    Previous findings suggest that religion has a specific impact on attentional processes. Here we show that religion also affects action control. Experiment 1 compared Dutch Calvinists and Dutch atheists, matched for age, sex, intelligence, education, and cultural and socio-economic background, and Ex

  9. Domain-General and Domain-Specific Creative-Thinking Tests: Effects of Gender and Item Content on Test Performance

    Science.gov (United States)

    Hong, Eunsook; Peng, Yun; O'Neil, Harold F., Jr.; Wu, Junbin

    2013-01-01

    The study examined the effects of gender and item content of domain-general and domain-specific creative-thinking tests on four subscale scores of creative-thinking (fluency, flexibility, originality, and elaboration). Chinese tenth-grade students (234 males and 244 females) participated in the study. Domain-general creative thinking was measured…

  10. Testing the McSad depression specific classification system in patients with somatic conditions : validity and performance

    NARCIS (Netherlands)

    Papageorgiou, Katerina; Vermeulen, Karin M.; Schroevers, Maya J.; Buskens, Erik; Ranchor, Adelita V.

    2013-01-01

    Background: Valuations of depression are useful to evaluate depression interventions offered to patients with chronic somatic conditions. The only classification system to describe depression developed specifically for valuation purposes is the McSad, but it has not been used among somatic patients.

  11. Engineered waste-package-system design specification

    Energy Technology Data Exchange (ETDEWEB)

    1983-05-01

    This report documents the waste package performance requirements and geologic and waste form data bases used in developing the conceptual designs for waste packages for salt, tuff, and basalt geologies. The data base reflects the latest geotechnical information on the geologic media of interest. The parameters or characteristics specified primarily cover spent fuel, defense high-level waste, and commercial high-level waste forms. The specification documents the direction taken during the conceptual design activity. A separate design specification will be developed prior to the start of the preliminary design activity.

  12. Age-specific performance of the revised cardiac risk index for predicting cardiovascular risk in elective noncardiac surgery

    DEFF Research Database (Denmark)

    Andersson, Charlotte; Wissenberg, Mads; Jørgensen, Mads Emil;

    2015-01-01

    BACKGROUND: The revised cardiac risk index (RCRI) holds a central role in preoperative cardiac risk stratification in noncardiac surgery. Its performance in unselected populations, including different age groups, has, however, not been systematically investigated. We assessed the relationship......%, 71%, 64%, 66%, and 67% in patients aged ≤ 55, 56 to 65, 66 to 75, 76 to 85, and >85 years, respectively; the negative predictive values were >98% across all age groups. CONCLUSIONS: In a nationwide unselected cohort, the performance of the RCRI was similar to that of the original cohort. Having ≥ 1...

  13. DESIGN OF AQUIFER REMEDIATION SYSTEMS: (2) Estimating site-specific performance and benefits of partial source removal

    Science.gov (United States)

    A Lagrangian stochastic model is proposed as a tool that can be utilized in forecasting remedial performance and estimating the benefits (in terms of flux and mass reduction) derived from a source zone remedial effort. The stochastic functional relationships that describe the hyd...

  14. Directed evolution of a bacterial alpha-amylase: toward enhanced pH-performance and higher specific activity.

    Science.gov (United States)

    Bessler, Cornelius; Schmitt, Jutta; Maurer, Karl-Heinz; Schmid, Rolf D

    2003-10-01

    alpha-Amylases, in particular, microbial alpha-amylases, are widely used in industrial processes such as starch liquefaction and pulp processes, and more recently in detergency. Due to the need for alpha-amylases with high specific activity and activity at alkaline pH, which are critical parameters, for example, for the use in detergents, we have enhanced the alpha-amylase from Bacillus amyloliquefaciens (BAA). The genes coding for the wild-type BAA and the mutants BAA S201N and BAA N297D were subjected to error-prone PCR and gene shuffling. For the screening of mutants we developed a novel, reliable assay suitable for high throughput screening based on the Phadebas assay. One mutant (BAA 42) has an optimal activity at pH 7, corresponding to a shift of one pH unit compared to the wild type. BAA 42 is active over a broader pH range than the wild type, resulting in a 5-fold higher activity at pH 10. In addition, the activity in periplasmic extracts and the specific activity increased 4- and 1.5-fold, respectively. Another mutant (BAA 29) possesses a wild-type-like pH profile but possesses a 40-fold higher activity in periplasmic extracts and a 9-fold higher specific activity. The comparison of the amino acid sequences of these two mutants with other homologous microbial alpha-amylases revealed the mutation of the highly conserved residues W194R, S197P, and A230V. In addition, three further mutations were found K406R, N414S, and E356D, the latter being present in other bacterial alpha-amylases.

  15. Cardiac-Specific Disruption of GH Receptor Alters Glucose Homeostasis While Maintaining Normal Cardiac Performance in Adult Male Mice.

    Science.gov (United States)

    Jara, Adam; Liu, Xingbo; Sim, Don; Benner, Chance M; Duran-Ortiz, Silvana; Qian, Yanrong; List, Edward O; Berryman, Darlene E; Kim, Jason K; Kopchick, John J

    2016-05-01

    GH is considered necessary for the proper development and maintenance of several tissues, including the heart. Studies conducted in both GH receptor null and bovine GH transgenic mice have demonstrated specific cardiac structural and functional changes. In each of these mouse lines, however, GH-induced signaling is altered systemically, being decreased in GH receptor null mice and increased in bovine GH transgenic mice. Therefore, to clarify the direct effects GH has on cardiac tissue, we developed a tamoxifen-inducible, cardiac-specific GHR disrupted (iC-GHRKO) mouse line. Cardiac GH receptor was disrupted in 4-month-old iC-GHRKO mice to avoid developmental effects due to perinatal GHR gene disruption. Surprisingly, iC-GHRKO mice showed no difference vs controls in baseline or postdobutamine stress test echocardiography measurements, nor did iC-GHRKO mice show differences in longitudinal systolic blood pressure measurements. Interestingly, iC-GHRKO mice had decreased fat mass and improved insulin sensitivity at 6.5 months of age. By 12.5 months of age, however, iC-GHRKO mice no longer had significant decreases in fat mass and had developed glucose intolerance and insulin resistance. Furthermore, investigation via immunoblot analysis demonstrated that iC-GHRKO mice had appreciably decreased insulin stimulated Akt phosphorylation, specifically in heart and liver, but not in epididymal white adipose tissue. These changes were accompanied by a decrease in circulating IGF-1 levels in 12.5-month-old iC-GHRKO mice. These data indicate that whereas the disruption of cardiomyocyte GH-induced signaling in adult mice does not affect cardiac function, it does play a role in systemic glucose homeostasis, in part through modulation of circulating IGF-1.

  16. Effects of increasing dietary concentrations of specific structured triacylglycerides on performance and nitrogen and energy metabolism in broiler chickens

    DEFF Research Database (Denmark)

    Zheng, C.T.; Jørgensen, Henning; Høy, Carl-Erik;

    2006-01-01

    1. Specific structured triacylglycerides (STG) containing medium chain fatty acids in sn-1,3 positions and along chain fatty acid in sn-2 position were prepared from rapeseed oil and capric acid (C10:0). 2. A total of 80 female broiler chickens ( Ross 208) were randomly allocated into five dietary...... receiving STG. Heat production (HE) was slightly lower in the STG groups. 5. More of the dietary fat was oxidised when more STG was added, although the total amount of fat in the diets was kept constant....

  17. Results from an inter-laboratory comparison of pneumococcal serotype-specific IgG measurement and critical parameters that affect assay performance.

    Science.gov (United States)

    Balloch, A; Licciardi, P V; Leach, A; Nurkka, A; Tang, M L K

    2010-02-01

    Quantitation of specific IgG to polysaccharides (serotypes) of Streptococcus pneumoniae provides the basis for evaluating vaccine efficacy. Different enzyme-linked immunosorbent assay (ELISA) methods are used internationally, making comparisons between laboratories difficult. We undertook an inter-laboratory comparison between two international laboratories performing serotype-specific IgG ELISAs using a panel of well-characterized serum samples: the Murdoch Childrens Research Institute Pneumococcal Laboratory (Melbourne, Australia) and the Vaccine Immunology Laboratory, National Public Health Institute (Helsinki, Finland). While good agreement was found for the inter-laboratory comparison for most serotypes, differences in ELISA methodology influenced specific IgG measurement. Therefore, use of the World Health Organization (WHO)-based ELISA methods for measurement of serotype-specific IgG is reliable, accurate and provides consistent results between international laboratories.

  18. SMaRT-OnlineWDN D3.1: Detailed specification of the performance criteria and application of sensor placement

    OpenAIRE

    Piller, O.; Deuerlein, J.; Bernard, T; Sedehizade, F.

    2014-01-01

    Drinking water distribution networks are exposed to malicious or accidental contamination. Several levels of responses are conceivable. One of them consists of installing a sensor network to monitor the system in real time. Once a contamination has been detected, it is also important to take appropriate counter-measures. The SMaRT-OnlineWDN project relies on modelling to predict both hydraulics and water quality. An online model makes it possible to identify the contaminant source and perform...

  19. Quasi-three dimensional hydraulic design and performance calculation of high specific speed mixed-flow pump

    Science.gov (United States)

    Su, M.; Zhang, Y. X.; Zhang, J. Y.; Hou, H. C.

    2016-05-01

    According to the basic parameters of 211-80 high specific speed mixed-flow pump, based on the quasi-three dimensional flow theory, the hydraulic design of impeller and its matching spaced guide vanes for high specific speed mixed flow pump was completed, in which the iterative calculation of S 1, S 2 stream surfaces was employed to obtain meridional flow fields and the point-by-point integration method was employed to draw blade camber lines. Blades are thickened as well as blade leading edges are smoothed in the conformal mapping surface. Subsequently the internal fields of the whole flow passage of the designed pump were simulated by using RANS equations with RNG k-ε two-equation turbulent model. The results show that, compared with the 211-80 model, the hydraulic efficiency of the designed pump at the optimal flow rate increases 9.1%. The hydraulic efficiency of designed pump in low flow rate condition (78% designed flow rate) increases 6.46%. The hydraulic efficiency in high flow rate areas increases obviously and there is no bad phenomenon of suddenly decrease of hydraulic efficiency in model pump. From the distributions of velocity and pressure fields, it can be seen that the flow in impeller is uniform and the increase of pressure is gentle. There are no obvious impact phenomenon on impeller inlet and obvious wake shedding vortex phenomenon from impeller outlet to guide vanes inlet.

  20. Simulator sickness when performing gaze shifts within a wide field of view optic flow environment: preliminary evidence for using virtual reality in vestibular rehabilitation

    Directory of Open Access Journals (Sweden)

    Whitney Susan L

    2004-12-01

    Full Text Available Abstract Background Wide field of view virtual environments offer some unique features that may be beneficial for use in vestibular rehabilitation. For one, optic flow information extracted from the periphery may be critical for recalibrating the sensory processes used by people with vestibular disorders. However, wide FOV devices also have been found to result in greater simulator sickness. Before a wide FOV device can be used in a clinical setting, its safety must be demonstrated. Methods Symptoms of simulator sickness were recorded by 9 healthy adult subjects after they performed gaze shifting tasks to locate targets superimposed on an optic flow background. Subjects performed 8 trials of gaze shifting on each of the six separate visits. Results The incidence of symptoms of simulator sickness while subjects performed gaze shifts in an optic flow environment was lower than the average reported incidence for flight simulators. The incidence was greater during the first visit compared with subsequent visits. Furthermore, the incidence showed an increasing trend over the 8 trials. Conclusion The performance of head unrestrained gaze shifts in a wide FOV optic flow environment is tolerated well by healthy subjects. This finding provides rationale for testing these environments in people with vestibular disorders, and supports the concept of using wide FOV virtual reality for vestibular rehabilitation.

  1. Attachment and Interpersonal Specifics if Well-Being in Relation to Employee Job Performance of Contact Centres

    Directory of Open Access Journals (Sweden)

    Ivana Tomanová Čergeťová

    2015-01-01

    Full Text Available The research is focused on exploring of multiple relations between interpersonal and attachment characteristics, job performance, job satisfaction and well-being of employees in contact centres. Global assessment of well-being represents cognitive and emotional approach of one ́s life as a whole. However, global view can be deformed by distorted perception of reality, so therefore it is necessary to evaluate well-being not only in general, but also as many different aspects of human life. This study is focused on working environment as one of thesignificant parts of life. Our sample consisted of 176 employees of contact centres, 116 of them were women (65,91% and 60 men (34,09%. The age range was from 21 to 56 years (average –29,78 years. The average length of employment of a telephone operator was 14 months. The major part of workforce were workers in permanent employment – 54,55% (N = 96, performance contract employees – 40,91% (N = 72, students employed based on agreement on temporary job of student – 3,41% (N = 6 and freelancers / self-employed – 1,14% (N = 2. The quantitative and qualitative data were obtained using standardised questionnaires. A short form of Egna Minnen Beträffande Uppfostran (s-E.M.B.U.; Willem et al., 1999, which is bas ed on Bowlby attachment theory, was used to measure attachment style. The interpersonal characteristics were measured by Interpersonal Check List (ICL; Kožený & Ganický, 1976. The job performance was measured by means of a call centre software system called Aheeva CCS Manager. Other questionnaires were focused on job satisfaction and well-being. The evaluation of job satisfaction was realised by means of Minnesota Satisfaction Questionnaire (MSQ; Weiss et al., 1967 and well-being was measured by means of two questionnaires - Satisfaction with Life Scale (SWLS; Diener, Emmons, Larsen, & Griffin, 1985 and Scales of Psychological Well-Being (SPWB; Ryff, 1989. The results of this study

  2. Specific LED-based red light photo-stimulation procedures improve overall sperm function and reproductive performance of boar ejaculates

    OpenAIRE

    2016-01-01

    The present study evaluated the effects of exposing liquid-stored boar semen to different red light LED regimens on sperm quality and reproductive performance. Of all of the tested photo-stimulation procedures, the best pattern consisted of 10 min light, 10 min rest and 10 min of further light (10-10-10 pattern). This pattern induced an intense and transient increase in the majority of motility parameters, without modifying sperm viability and acrosome integrity. While incubating non-photo-st...

  3. Preliminary design package for solar heating and hot water system

    Energy Technology Data Exchange (ETDEWEB)

    Levine, P.; Meyer, R.; White, James S.

    1977-01-01

    A collection of documents submitted by the Fern Engineering Company for the preliminary design review on the development of two prototype solar heating and hot water systems is presented. The information includes system certification, system functional description, system configuration, system specification, system performance and other documents pertaining to the progress and the design of the system. This system, which is intended for use in the normal single-family residence, consists of the following subsystems: collector, storage, control, transport, and Government-furnished Site Data Acquisition. One of the two prototype units will be installed in Lansing, Michigan, and the other in Tunkhannock, Pennsylvania.

  4. Comparing the Predictive Value of Task Performance and Task-Specific Sensitivity During Physical Function Testing Among People With Knee Osteoarthritis.

    Science.gov (United States)

    Wideman, Timothy H; Edwards, Robert R; Finan, Patrick H; Haythornthwaite, Jennifer A; Smith, Michael T

    2016-05-01

    Study Design Cross-sectional cohort. Background Knee osteoarthritis (OA) is a leading cause of pain and mobility restriction. Past research has advocated the use of brief, functional tasks to evaluate these restrictions, such as the six-minute-walk test and the timed up-and-go test. Typically, only task performance (ie, walking distance, completion time) is used to inform clinical practice. Recent research, however, suggests that individual variance in how people feel while completing these tasks (ie, task sensitivity) might also have important clinical value. Objective To compare the predictive value of task performance and task-specific sensitivity in determining OA-related physical function (measured by the Western Ontario and McMaster Universities Osteoarthritis Index) and pain-related interference (measured by the Multidimensional Pain Inventory). Methods One hundred eight participants with chronic knee OA completed the six-minute-walk test and the timed up-and-go test, and reported levels of discomfort and affective response (mood) associated with each test. Results In separate regression models, both task performance and task-specific sensitivity predicted OA-related physical function and pain-related interference. A final regression model including all significant predictors showed that task-specific sensitivity (specifically, post-six-minute-walk discomfort) emerged as a unique predictor of both outcomes. Conclusion These findings highlight the value of a novel clinical assessment strategy for patients with knee OA. While clinicians commonly focus on how patients perform on standardized functional tasks, these results highlight the value of also considering levels of posttask sensitivity. Measures of task-specific sensitivity relate to Maitland's concept of pain irritability, which may be a useful framework for future research on sensitizing factors and pain-related disability. J Orthop Sports Phys Ther 2016;46(5):346-356. Epub 21 Mar 2016. doi:10

  5. Right- and left-hand performance on the Rey-Osterrieth Complex Figure: A preliminary study in non-clinical sample of right handed people.

    Science.gov (United States)

    Yamashita, Hikari

    2010-06-01

    Intermanual differences in performing the Rey-Osterrieth Complex Figure Test (ROCFT) were experimentally investigated. Undergraduate participants (n = 120; 60 men, 60 women) were randomly assigned to one of four groups based on the hand used in a copy trial and a recall test. Hand use had a minimal effect on performance in the copy trial. However, recall accuracy was lower when the non-dominant left hand was used in the copy trial than when the dominant right hand was used, regardless of the hand used in the recall test. These findings are important from a clinical perspective, especially in cases in which patients use the non-dominant hand due to hemiplegia of the dominant hand when conducting the ROCFT.

  6. Effect of Whole-Body-Vibration Training on Trunk-Muscle Strength and Physical Performance in Healthy Adults: Preliminary Results of a Randomized Controlled Trial.

    Science.gov (United States)

    Maeda, Noriaki; Urabe, Yukio; Sasadai, Junpei; Miyamoto, Akira; Murakami, Masahito; Kato, Junichi

    2016-12-01

    Whole-body-vibration (WBV) stimulus equipment has been used as a new training method for health promotion. Its use in the clinic has expanded to the field of sports and rehabilitation for disabled patients. WBV training is rapidly gaining popularity in health and fitness centers as an alternative method for improving muscle performance. Acute positive effects of WBV have been shown on lower-extremity muscle power and vertical-jump ability; however, there have not been any studies focusing on the long-term effects of WBV for trunk muscle and dynamic balance. To investigate the effects of an 8-wk program of WBV in combination with trunk-muscle training on muscle performance in healthy, untrained adults. Laboratory-based, repeated-measures study. University laboratory. 20 healthy university men. Participants were randomly assigned to a WBV or non-WBV group. The WBV group performed a trunk-muscle-training program in combination with WBV; the non-WBV group performed the same muscle-training program without WBV for 8 wk. In the pre- and posttraining period, the participants were evaluated using the Functional Movement Screen (FMS), Y Balance Test (Y-test) (anterior, posteromedial, and posterolateral reach), trunk-muscle isometric strength (flexor, extensor, and flexor:extensor ratio), squat jump, and countermovement jump. The WBV group had greater improvement than the non-WBV group in both trunk-flexor muscle strength (P = .02) and the Y-test (anterior reach) (P = .004) between pre- and posttraining. Adding WBV to a trunk-muscle-strengthening program may improve trunk-flexor isometric strength and anterior reach during the Y-test more than training without WBV. The WBV protocol used in this study had no significant impact on FMS scores, squat jumping, countermovement jumping, trunk-extensor isometric strength, or trunk flexor:extensor ratio.

  7. Preoperative liver functional volumetry performed by 3D-99mTc-GSA scintigraphy/vascular fusion imaging using SYNAPSE VINCENT:a preliminary study

    Institute of Scientific and Technical Information of China (English)

    Hiroshi Yoshida; Hiroshi Makino; Tadashi Yokoyama; Hiroshi Maruyama; Atsushi Hirakata; Junji Ueda; Yasuhiro Mamada; Nobuhiko Taniai; Eiji Uchida

    2016-01-01

    Aim: The present study was designed to evaluate the feasibility of preoperative liver functional volumetry performed by 3D-technetium-99m-diethylenetriaminepentaacetic acid-galactosyl-human serum albumin (99mTc-GSA) scintigraphy/vascular fusion imaging using SYNAPSE VINCENT and to examine the discrepancy between conventional and functional volumetry.Methods: The study group comprised 15 patients who underwent preoperative 3-dimensional (3D)-99mTc-GSA scintigraphy/vascular fusion imaging using SYNAPSE VINCENT software before hepatectomy between July 2014 and August 2015. The diagnosis was hepatocelular carcinoma (n = 4), metastatic liver tumor (n = 10), or intrahepatic cholangiocarcinoma (n = 1). Right hepatectomy was performed in 2 patients, left hepatectomy in 3 patients, right posterior sectionectomy in 3 patients, segmentectomy in 2 patients, and partial hepatectomy in 4 patients. 99mTc-GSA scintigraphy and computed tomography (CT) were performed to construct 3D-99mTc-GSA scintigraphy/vascular fused images. The conventional volume ratio of the planned resection region without tumor (% CT), and the functional volume ratio of the planned resection region without tumor (% GSA) were calculated. The discrepancy ratio was calculated as folows: discrepancy ratio = 100 - % GSA/ % CT × 100 (%).Results: The % GSA (17.9 ± 16.7%) was signiifcantly lower than the % CT (21.5 ± 17.6%) (P < 0.036). In al except 2 patients, the % GSA was lower than the % CT. The discrepancy ratio ranged from -4% to 75% (median, 20.7%).Conclusion: 3D-99mTc-GSA scintigraphy/vascular fused images constructed using SYNAPSE VINCENT were useful for noninvasively performing functional liver volumetry in patients scheduled to undergo various patterns of hepatectomy. In planned resection regions without tumor, the functional volume ratio was about 20% lower than the conventional volume ratio.

  8. Performing target specific band reduction using artificial neural networks and assessment of its efficacy using various target detection algorithms

    Science.gov (United States)

    Yadav, Deepti; Arora, M. K.; Tiwari, K. C.; Ghosh, J. K.

    2016-04-01

    Hyperspectral imaging is a powerful tool in the field of remote sensing and has been used for many applications like mineral detection, detection of landmines, target detection etc. Major issues in target detection using HSI are spectral variability, noise, small size of the target, huge data dimensions, high computation cost, complex backgrounds etc. Many of the popular detection algorithms do not work for difficult targets like small, camouflaged etc. and may result in high false alarms. Thus, target/background discrimination is a key issue and therefore analyzing target's behaviour in realistic environments is crucial for the accurate interpretation of hyperspectral imagery. Use of standard libraries for studying target's spectral behaviour has limitation that targets are measured in different environmental conditions than application. This study uses the spectral data of the same target which is used during collection of the HSI image. This paper analyze spectrums of targets in a way that each target can be spectrally distinguished from a mixture of spectral data. Artificial neural network (ANN) has been used to identify the spectral range for reducing data and further its efficacy for improving target detection is verified. The results of ANN proposes discriminating band range for targets; these ranges were further used to perform target detection using four popular spectral matching target detection algorithm. Further, the results of algorithms were analyzed using ROC curves to evaluate the effectiveness of the ranges suggested by ANN over full spectrum for detection of desired targets. In addition, comparative assessment of algorithms is also performed using ROC.

  9. Plant performance on Mediterranean green roofs: interaction of species-specific hydraulic strategies and substrate water relations.

    Science.gov (United States)

    Raimondo, Fabio; Trifilò, Patrizia; Lo Gullo, Maria A; Andri, Sergio; Savi, Tadeja; Nardini, Andrea

    2015-01-20

    Recent studies have highlighted the ecological, economic and social benefits assured by green roof technology to urban areas. However, green roofs are very hostile environments for plant growth because of shallow substrate depths, high temperatures and irradiance and wind exposure. This study provides experimental evidence for the importance of accurate selection of plant species and substrates for implementing green roofs in hot and arid regions, like the Mediterranean area. Experiments were performed on two shrub species (Arbutus unedo L. and Salvia officinalis L.) grown in green roof experimental modules with two substrates slightly differing in their water retention properties, as derived from moisture release curves. Physiological measurements were performed on both well-watered and drought-stressed plants. Gas exchange, leaf and xylem water potential and also plant hydraulic conductance were measured at different time intervals following the last irrigation. The substrate type significantly affected water status. Arbutus unedo and S. officinalis showed different hydraulic responses to drought stress, with the former species being substantially isohydric and the latter one anisohydric. Both A. unedo and S. officinalis were found to be suitable species for green roofs in the Mediterranean area. However, our data suggest that appropriate choice of substrate is key to the success of green roof installations in arid environments, especially if anisohydric species are employed.

  10. Lab-scale co-digestion of kitchen waste and brown water for a preliminary performance evaluation of a decentralized waste and wastewater management.

    Science.gov (United States)

    Lavagnolo, Maria Cristina; Girotto, Francesca; Hirata, Osamu; Cossu, Raffaello

    2017-08-01

    An overall interaction is manifested between wastewater and solid waste management schemes. At the Laboratory of Environmental Engineering (LISA) of the University of Padova, Italy, the scientific and technical implications of putting into practice a decentralized waste and wastewater treatment based on the separation of grey water, brown water (BW - faecal matter) and yellow water (YW - urine) are currently undergoing investigation in the Aquanova Project. An additional aim of this concept is the source segregation of kitchen waste (KW) for subsequent anaerobic co-digestion with BW. To determine an optimal mixing ratio and temperature for use in the treatment of KW, BW, and eventually YW, by means of anaerobic digestion, a series of lab-scale batch tests were performed. Organic mixtures of KW and BW performed much better (max. 520mlCH4/gVS) in terms of methane yields than the individual substrates alone (max. 220mlCH4/gVS). A small concentration of urine proved to have a positive effect on anaerobic digestion performance, possibly due to the presence of micronutrients in YW. When considering high YW concentrations in the anaerobically digested mixtures, no ammonia inhibition was observed until a 30% and 10% YW content was added under mesophilic and thermophilic conditions, respectively. Copyright © 2017 Elsevier Ltd. All rights reserved.

  11. A preliminary study of the effects of individual response to challenge tests and stress induced by humans on learning performance of weaned piglets (Sus scrofa).

    Science.gov (United States)

    Brajon, Sophie; Laforest, Jean-Paul; Schmitt, Océane; Devillers, Nicolas

    2016-08-01

    This study investigated whether individual behavioural characteristics of piglets and stress induced by experience with humans can influence learning performance. After weaning, piglets received a chronic experience with humans to modulate their emotional state: rough (ROU), gentle (GEN), or minimal (MIN) experience. Simultaneously, they were trained on a discrimination task. Afterward, their behaviour during challenge tests was assessed. The first learning step of the task involved associating a positive sound cue with a response (approach a trough) and success of piglets depended mostly on motivation to seek for reward. Although the experience with humans did not have direct effect, the degree of fear of handler, measured based on their reactivity to a human approach test, was related to motivation to seek rewards and learning speed of this first step in stressed ROU piglets, but not in MIN and GEN piglets. In contrast, the second learning step was more cognitively challenging, since it involved discrimination learning, including negative cues during which piglets had to learn to avoid the trough. Locomotion activity, measured during an open-field test, was associated with performance of the discrimination learning. To conclude, fearfulness towards humans and locomotion activity are linked with learning performance in relation to task complexity, highlighting the necessity to take into account these factors in animal research and management.

  12. Plasma facing materials and components for future fusion devices—development, characterization and performance under fusion specific loading conditions

    Science.gov (United States)

    Linke, J.

    2006-04-01

    The plasma exposed components in existing and future fusion devices are strongly affected by the plasma material interaction processes. These mechanisms have a strong influence on the plasma performance; in addition they have major impact on the lifetime of the plasma facing armour and the joining interface between the plasma facing material (PFM) and the heat sink. Besides physical and chemical sputtering processes, high heat quasi-stationary fluxes during normal and intense thermal transients are of serious concern for the engineers who develop reliable wall components. In addition, the material and component degradation due to intense fluxes of energetic neutrons is another critical issue in D-T-burning fusion devices which requires extensive R&D. This paper presents an overview on the materials development and joining, the testing of PFMs and components, and the analysis of the neutron irradiation induced degradation.

  13. Comparison of the performance of {sup 18}F-FP-CIT brain PET/MR and simultaneous PET/CT: A preliminary study

    Energy Technology Data Exchange (ETDEWEB)

    Kwon, Sang Don; Chun, Kyung Ah [Dept. of Nuclear Medicine, Yeungnam University Hospital, Daegu (Korea, Republic of)

    2016-09-15

    {sup 18}F-FP-CIT [{sup 1'}8F-fluorinated N-3-fluoropropyl-2-beta-carboxymethoxy-3-beta-(4-iodophenyl) nortropane] has been well established and used for the differential diagnosis of atypical parkinsonian disorders. Recently, combined positron emission tomography (PET)/magnetic resonance (MR) was proposed as a viable alternative to PET/computed tomography (CT). The aim of this study was to compare the performances of conventional {sup 18}F-FP-CIT brain PET/CT and simultaneous PET/MR by visual inspection and quantitative analysis. Fifteen consecutive patients clinically suspected of having Parkinson's disease were recruited for the study.{sup 18}F-FP-CIT PET was performed during PET/CT and PET/MR. PET/CT image acquisition was started 90 min after intravenous injection of {sup 18}F-FP-CIT and then PET/MR images were acquired. Dopamine transporter (DAT) density in bilateral striatal subregions was assessed visually. Quantitative analyses were performed on bilateral striatal volumes of interest (VOIs) using average standardized uptake values (SUVmeans). Intraclass correlation coefficients (ICCs) and their 95 % confidence intervals (CIs) were assessed to compare PET/CT and PET/MR data. Bland-Altman plots were drawn to perform method-comparisons. All subjects showed a preferential decrease in DAT binding in the posterior putamen (PP), with relative sparing of the ventral putamen (VP). Bilateral striatal subregional binding ratio (BR) determined PET/CT and PET/MR demonstrated close interequipment correspondence (BRright caudate - ICC, 0.944; 95 % CI, 0.835-0.981, BRleft caudate - ICC, 0.917; 95 % CI, 0.753-0.972, BRright putamen - ICC, 0.976; 95 % CI, 0.929-0.992 and BRleft putamen - ICC, 0.970; 95 % CI, 0.911-0.990, respectively), and Bland-Altman plots showed interequipment agreement between the two modalities. It is known that MR provides more information about anatomical changes associated with brain diseases and to enable the anatomical allocations of

  14. Performance testing of the neutron flux monitors from 10keV to 1MeV developed for BNCT: A preliminary study.

    Science.gov (United States)

    Guan, Xingcai; Manabe, Masanobu; Tamaki, Shingo; Sato, Fuminobu; Murata, Isao; Wang, Tieshan

    2017-07-01

    The neutron flux monitors from 10keV to 1MeV designed for boron neutron capture therapy (BNCT) were experimentally tested with prototype monitors in an appropriate neutron field produced at the intense deuterium-tritium neutron source facility OKTAVIAN of Osaka University, Japan. The experimental test results and related analysis indicated that the performance of the monitors was good and the neutron fluxes from 10keV to 1MeV of practical BNCT neutron sources can be measured within 10% by the monitors. Copyright © 2017 Elsevier Ltd. All rights reserved.

  15. Exploiting Performance of Different Low-Cost Sensors for Small Amplitude Oscillatory Motion Monitoring: Preliminary Comparisons in View of Possible Integration

    OpenAIRE

    Elisa Benedetti; Roberta Ravanelli; Monica Moroni; Andrea Nascetti; Mattia Crespi

    2016-01-01

    We address the problem of low amplitude oscillatory motion detection through different low-cost sensors: a LIS3LV02DQ MEMS accelerometer, a Microsoft Kinect v2 range camera, and a uBlox 6 GPS receiver. Several tests were performed using a one-direction vibrating table with different oscillation frequencies (in the range 1.5–3 Hz) and small challenging amplitudes (0.02 m and 0.03 m). A Mikrotron EoSens high-resolution camera was used to give reference data. A dedicated software tool was develo...

  16. The effect of auditory perception training on reading performance of the 8-9-year old female students with dyslexia: A preliminary study

    Directory of Open Access Journals (Sweden)

    Nafiseh Vatandoost

    2014-01-01

    Full Text Available Background and Aim: Dyslexia is the most common learning disability. One of the main factors have role in this disability is auditory perception imperfection that cause a lot of problems in education. We aimed to study the effect of auditory perception training on reading performance of female students with dyslexia at the third grade of elementary school.Methods: Thirty-eight female students at the third grade of elementary schools of Khomeinishahr City, Iran, were selected by multistage cluster random sampling of them, 20 students which were diagnosed dyslexic by Reading test and Wechsler test, devided randomly to two equal groups of experimental and control. For experimental group, during ten 45-minute sessions, auditory perception training were conducted, but no intervention was done for control group. An participants were re-assessed by Reading test after the intervention (pre- and post- test method. Data were analyed by covariance test.Results: The effect of auditory perception training on reading performance (81% was significant (p<0.0001 for all subtests execpt the separate compound word test.Conclusion: Findings of our study confirm the hypothesis that auditory perception training effects on students' functional reading. So, auditory perception training seems to be necessary for the students with dyslexia.

  17. Preliminary Results of an Altitude-Wind-Tunnel Investigation of a TG-100A Gas Turbine-Propeller Engine. 4; Compressor and Turbine Performance Characteristics

    Science.gov (United States)

    Wallner, Lewis E.; Saari, Martin J.

    1947-01-01

    As part of an investigation of the performance and operational characteristics of the TG-100A gas turbine-propeller engine, conducted in the Cleveland altitude wind tunnel, the performance characteristics of the compressor and the turbine were obtained. The data presented were obtained at a compressor-inlet ram-pressure ratio of 1.00 for altitudes from 5000 to 35,000 feet, engine speeds from 8000 to 13,000 rpm, and turbine-inlet temperatures from 1400 to 2100R. The highest compressor pressure ratio was 6.15 at a corrected air flow of 23.7 pounds per second and a corrected turbine-inlet temperature of 2475R. Peak adiabatic compressor efficiencies of about 77 percent were obtained near the value of corrected air flow corresponding to a corrected engine speed of 13,000 rpm. This maximum efficiency may be somewhat low, however, because of dirt accumulations on the compressor blades. A maximum adiabatic turbine efficiency of 81.5 percent was obtained at rated engine speed for all altitudes and turbine-inlet temperatures investigated.

  18. Preliminary Results of an Altitude-Wind-Tunnel Investigation of an Axial-Flow Gas Turbine-Propeller Engine. 4; Compressor and Turbine Performance Characteristics

    Science.gov (United States)

    Wallner, Lewis E.; Saari, Martin J.

    1948-01-01

    As part of an investigation of the performance and operational characteristics of the axial-flow gas turbine-propeller engine, conducted in the Cleveland altitude wind tunnel, the performance characteristics of the compressor and the turbine were obtained. The data presented were obtained at a compressor-inlet ram-pressure ratio of 1.00 for altitudes from 5000 to 35,000 feet, engine speeds from 8000 to 13,000 rpm, and turbine-inlet temperatures from 1400 to 2100 R. The highest compressor pressure ratio obtained was 6.15 at a corrected air flow of 23.7 pounds per second and a corrected turbine-inlet temperature of 2475 R. Peak adiabatic compressor efficiencies of about 77 percent were obtained near the value of corrected air flow corresponding to a corrected engine speed of 13,000 rpm. This maximum efficiency may be somewhat low, however, because of dirt accumulations on the compressor blades. A maximum adiabatic turbine efficiency of 81.5 percent was obtained at rated engine speed for all altitudes and turbine-inlet temperatures investigated.

  19. Performance of the Fecal Immunochemical Test for Colorectal Cancer Screening Using Different Stool-Collection Devices: Preliminary Results from a Randomized Controlled Trial.

    Science.gov (United States)

    Shin, Hye Young; Suh, Mina; Baik, Hyung Won; Choi, Kui Son; Park, Boyoung; Jun, Jae Kwan; Hwang, Sang-Hyun; Kim, Byung Chang; Lee, Chan Wha; Oh, Jae Hwan; Lee, You Kyoung; Han, Dong Soo; Lee, Do-Hoon

    2016-11-15

    We are in the process of conducting a randomized trial to determine whether compliance with the fecal immunochemical test (FIT) for colorectal cancer screening differs according to the stool-collection method. This study was an interim analysis of the performance of two stool-collection devices (sampling bottle vs conventional container). In total, 1,701 individuals (age range, 50 to 74 years) were randomized into the sampling bottle group (intervention arm) or the conventional container group (control arm). In both groups, we evaluated the FIT positivity rate, the positive predictive value for advanced neoplasia, and the detection rate for advanced neoplasia. The FIT positivity rates were 4.1% for the sampling bottles and 2.0% for the conventional containers; these values were significantly different. The positive predictive values for advanced neoplasia in the sampling bottles and conventional containers were 11.1% (95% confidence interval [CI], -3.4 to 25.6) and 12.0% (95% CI, -0.7 to 24.7), respectively. The detection rates for advanced neoplasia in the sampling bottles and conventional containers were 4.5 per 1,000 persons (95% CI, 2.0 to 11.0) and 2.4 per 1,000 persons (95% CI, 0.0 to 5.0), respectively. The impact of these findings on FIT screening performance was unclear in this interim analysis. This impact should therefore be evaluated in the final analysis following the final enrollment period.

  20. Preliminary performance assessment for the Waste Isolation Pilot Plant, December 1992. Volume 4: Uncertainty and sensitivity analyses for 40 CFR 191, Subpart B

    Energy Technology Data Exchange (ETDEWEB)

    1993-08-01

    Before disposing of transuranic radioactive waste in the Waste Isolation Pilot Plant (WIPP), the United States Department of Energy (DOE) must evaluate compliance with applicable long-term regulations of the United States Environmental Protection Agency (EPA). Sandia National Laboratories is conducting iterative performance assessments (PAs) of the WIPP for the DOE to provide interim guidance while preparing for a final compliance evaluation. This volume of the 1992 PA contains results of uncertainty and sensitivity analyses with respect to the EPA`s Environmental Protection Standards for Management and Disposal of Spent Nuclear Fuel, High-Level and Transuranic Radioactive Wastes (40 CFR 191, Subpart B). Additional information about the 1992 PA is provided in other volumes. Results of the 1992 uncertainty and sensitivity analyses indicate that, conditional on the modeling assumptions, the choice of parameters selected for sampling, and the assigned parameter-value distributions, the most important parameters for which uncertainty has the potential to affect compliance with 40 CFR 191B are: drilling intensity, intrusion borehole permeability, halite and anhydrite permeabilities, radionuclide solubilities and distribution coefficients, fracture spacing in the Culebra Dolomite Member of the Rustler Formation, porosity of the Culebra, and spatial variability of Culebra transmissivity. Performance with respect to 40 CFR 191B is insensitive to uncertainty in other parameters; however, additional data are needed to confirm that reality lies within the assigned distributions.