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Sample records for preliminary laboratory tests

  1. Modeling and Testing of EVs - Preliminary Study and Laboratory Development

    DEFF Research Database (Denmark)

    Yang, Guang-Ya; Marra, Francesco; Nielsen, Arne Hejde

    2010-01-01

    impact at different geographical areas, as well as driving and charging patterns. Electric circuit model is deployed in this work to represent the electrical properties of a lithium-ion battery. This paper reports the preliminary modeling and validation work based on manufacturer data sheet and realistic......Electric vehicles (EVs) are expected to play a key role in the future energy management system to stabilize both supply and consumption with the presence of high penetration of renewable generation. A reasonably accurate model of battery is a key element for the study of EVs behavior and the grid...... tests, followed by the suggestions towards a feasible battery model for further studies....

  2. Modeling and Testing of EVs - Preliminary Study and Laboratory Development

    DEFF Research Database (Denmark)

    Yang, Guang-Ya; Marra, Francesco; Nielsen, Arne Hejde;

    2010-01-01

    Electric vehicles (EVs) are expected to play a key role in the future energy management system to stabilize both supply and consumption with the presence of high penetration of renewable generation. A reasonably accurate model of battery is a key element for the study of EVs behavior and the grid...... tests, followed by the suggestions towards a feasible battery model for further studies....

  3. Laboratory Tests

    Science.gov (United States)

    Laboratory tests check a sample of your blood, urine, or body tissues. A technician or your doctor ... compare your results to results from previous tests. Laboratory tests are often part of a routine checkup ...

  4. Preliminary laboratory testing on the sound absorption of coupled cavity sonic crystal

    Science.gov (United States)

    Kristiani, R.; Yahya, I.; Harjana; Suparmi

    2016-11-01

    This paper focuses on the sound absorption performance of coupled cavity sonic crystal. It constructed by a pair of a cylindrical tube with different values in diameters. A laboratory test procedure after ASTM E1050 has been conducted to measure the sound absorption of the sonic crystal elements. The test procedures were implemented to a single coupled scatterer and also to a pair of similar structure. The results showed that using the paired structure bring a better possibility for increase the sound absorption to a wider absorption range. It also bring a practical advantage for setting the local Helmholtz resonant frequency to certain intended frequency.

  5. Preliminary rock mechanics laboratory: Investigation plan

    Energy Technology Data Exchange (ETDEWEB)

    Oschman, K.P.; Hummeldorf, R.G.; Hume, H.R.; Karakouzian, M.; Vakili, J.E.

    1987-01-01

    This document presents the rationale for rock mechanics laboratory testing (including the supporting analysis and numerical modeling) planned for the site characterization of a nuclear waste repository in salt. This plan first identifies what information is required for regulatory and design purposes, and then presents the rationale for the testing that satisfies the required information needs. A preliminary estimate of the minimum sampling requirements for rock laboratory testing during site characterization is also presented. Periodic revision of this document is planned.

  6. Design and preliminary test results of the 40 MW power supply at the National High Magnetic Field Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Boenig, H.J. [Los Alamos National Lab., NM (United States); Bogdan, F.; Morris, G.C. [ABB Drives Inc., New Berlin, WI (United States); Ferner, J.A.; Schneider-Muntau, H.J. [National High Magnetic Field Lab., Tallahassee, FL (United States); Rumrill, R.H.; Rumrill, R.S. [Alpha Scientific Electronics Inc., Hayward, CA (United States)

    1993-11-01

    Four highly stabilized, steady-state, 10 MW power supplies have been installed at the National High Magnetic Field Laboratory in Tallahassee, FL. Each supply consists of a 12.5 kV vacuum circuit breaker, two three-winding, step-down transformers, a 24-pulse rectifier with interphase reactors and freewheeling diodes, and a passive and an active filter. Two different transformer tap settings allow dc supply output voltages of 400 and 500 V. The rated current of a supply is 17 kA and each supply has a one hour overload capability of 20 kA. The power supply output bus system, including a reversing switch at the input and 2 {times} 16 disconnect switches at the output, connects each supply to 16 different magnet cells. The design of the power supply is described and preliminary test results with a supply feeding a 10 MW resistive load are presented.

  7. Preliminary Feasibility, Design, and Hazard Analysis of a Boiling Water Test Loop Within the Idaho National Laboratory Advanced Test Reactor National Scientific User Facility

    Energy Technology Data Exchange (ETDEWEB)

    Douglas M. Gerstner

    2009-05-01

    The Advanced Test Reactor (ATR) is a pressurized light-water reactor with a design thermal power of 250 MW. The principal function of the ATR is to provide a high neutron flux for testing reactor fuels and other materials. The ATR and its support facilities are located at the Idaho National Laboratory (INL). A Boiling Water Test Loop (BWTL) is being designed for one of the irradiation test positions within the. The objective of the new loop will be to simulate boiling water reactor (BWR) conditions to support clad corrosion and related reactor material testing. Further it will accommodate power ramping tests of candidate high burn-up fuels and fuel pins/rods for the commercial BWR utilities. The BWTL will be much like the pressurized water loops already in service in 5 of the 9 “flux traps” (region of enhanced neutron flux) in the ATR. The loop coolant will be isolated from the primary coolant system so that the loop’s temperature, pressure, flow rate, and water chemistry can be independently controlled. This paper presents the proposed general design of the in-core and auxiliary BWTL systems; the preliminary results of the neutronics and thermal hydraulics analyses; and the preliminary hazard analysis for safe normal and transient BWTL and ATR operation.

  8. FOOD SAFETY TESTING LABORATORY

    Data.gov (United States)

    Federal Laboratory Consortium — This laboratory develops screening assays, tests and modifies biosensor equipment, and optimizes food safety testing protocols for the military and civilian sector...

  9. Preliminary Report on Oak Ridge National Laboratory Testing of Drake/ACSS/MA2/E3X

    Energy Technology Data Exchange (ETDEWEB)

    Irminger, Philip [ORNL; Davis, Cody [General Cable Corporation; Temple, Bill [General Cable Corporation; Baker, Gord [General Cable Corporation; Starke, Michael R [ORNL

    2016-01-01

    A key to industry acceptance of a new technology is extensive validation in field trials. The Powerline Conductor Accelerated Test facility (PCAT) at Oak Ridge National Laboratory (ORNL) is specifically designed to evaluate the performance and reliability of a new conductor technology under real world conditions. The facility is set up to capture large amounts of data during testing. General Cable used the ORNL PCAT facility to validate the performance of TransPowr with E3X Technology a standard overhead conductor with an inorganic high emissivity, low absorptivity surface coating. Extensive testing has demonstrated a significant improvement in conductor performance across a wide range of operating temperatures, indicating that E3X Technology can provide a reduction in temperature, a reduction in sag, and an increase in ampacity when applied to the surface of any overhead conductor. This report provides initial results of that testing.

  10. Mechanical Testing Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — NETL’s Mechanical Testing Laboratory in Albany, OR, helps researchers investigate materials that can withstand the heat and pressure commonly found in fossil energy...

  11. Understanding Laboratory Tests

    Science.gov (United States)

    ... and Drug Administration (FDA) regulates the development and marketing of all laboratory tests that use test kits ... are of great interest in cancer medicine because research suggests that levels of ... sequencing methods are being developed to provide gene mutation profiles ...

  12. Wind Structural Testing Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — This facility provides office space for industry researchers, experimental laboratories, computer facilities for analytical work, and space for assembling components...

  13. Wind Structural Testing Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — This facility provides office space for industry researchers, experimental laboratories, computer facilities for analytical work, and space for assembling components...

  14. Metallurgical Laboratory and Components Testing

    Data.gov (United States)

    Federal Laboratory Consortium — In the field of metallurgy, TTC is equipped to run laboratory tests on track and rolling stock components and materials. The testing lab contains scanning-electron,...

  15. World of Forensic Laboratory Testing

    Science.gov (United States)

    ... Global Sites Search Help? The World of Forensic Laboratory Testing Share this page: Was this page helpful? ... made-for-television lab scenario, real-life forensic laboratories' analyses of evidence are much slower. For example, ...

  16. Preliminary Results of an On-Line, Multi-Spectrometer Fission Product Monitoring System to Support Advanced Gas Reactor Fuel Testing and Qualification in the Advanced Test Reactor at the Idaho National Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Dawn M. Scates; John K. Hartwell; John B. Walter; Mark W. Drigert

    2007-10-01

    The Advanced Gas Reactor -1 (AGR-1) experiment is the first experiment in a series of eight separate low enriched uranium (LEU) oxycarbide (UCO) tri-isotropic (TRISO) particle fuel (in compact form) experiments scheduled for placement in the Advanced Test Reactor (ATR) located at the Idaho National Laboratory (INL). The experiment began irradiation in the ATR with a cycle that reached full power on December 26, 2006 and will continue irradiation for about 2.5 years. During this time six separate capsules, will be irradiated in an inert sweep gas atmosphere with individual on-line fission product monitoring on its effluent to track performance of the fuel in each individual capsule during irradiation. The goals of the irradiation experiment is to provide irradiation performance data to support fuel process development, to qualify fuel for normal operating conditions, to support development and validation of fuel, and to provide irradiated fuel and materials for post irradiation examination (PIE) and safety testing. This paper presents the preliminary test details of the fuel performance, as measured by the control and acquisition software.

  17. Preliminary results of steel containment vessel model test

    Energy Technology Data Exchange (ETDEWEB)

    Luk, V.K.; Hessheimer, M.F. [Sandia National Labs., Albuquerque, NM (United States); Matsumoto, T.; Komine, K.; Arai, S. [Nuclear Power Engineering Corp., Tokyo (Japan); Costello, J.F. [Nuclear Regulatory Commission, Washington, DC (United States)

    1998-04-01

    A high pressure test of a mixed-scaled model (1:10 in geometry and 1:4 in shell thickness) of a steel containment vessel (SCV), representing an improved boiling water reactor (BWR) Mark II containment, was conducted on December 11--12, 1996 at Sandia National Laboratories. This paper describes the preliminary results of the high pressure test. In addition, the preliminary post-test measurement data and the preliminary comparison of test data with pretest analysis predictions are also presented.

  18. Laboratory Testing for Prescription Opioids

    OpenAIRE

    Milone, Michael C.

    2012-01-01

    Opioid analgesic misuse has risen significantly over the past two decades, and these drugs now represent the most commonly abused class of prescription medications. They are a major cause of poisoning deaths in the USA exceeding heroin and cocaine. Laboratory testing plays a role in the detection of opioid misuse and the evaluation of patients with opioid intoxication. Laboratories use both immunoassay and chromatographic methods (e.g., liquid chromatography with mass spectrometry detection),...

  19. Preliminary evaluation of a Neutron Calibration Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Alvarenga, Talysson S.; Neves, Lucio P.; Perini, Ana P.; Sanches, Matias P.; Mitake, Malvina B.; Caldas, Linda V.E., E-mail: talvarenga@ipen.br, E-mail: lpneves@ipen.br, E-mail: aperini@ipen.br, E-mail: msanches@ipen.br, E-mail: mbmitake@ipen.br, E-mail: lcaldas@ipen.br [Instituto de Pesquisas Energeticas e Nucleares (IPEN/CNEN-SP), Sao Paulo, SP (Brazil); Federico, Claudio A., E-mail: claudiofederico@ieav.cta.br [Instituto de Estudos Avancados (IEAv/DCTA), Sao Jose dos Campos, SP (Brazil). Dept. de Ciencia e Tecnologia Aeroespacial

    2013-07-01

    In the past few years, Brazil and several other countries in Latin America have experimented a great demand for the calibration of neutron detectors, mainly due to the increase in oil prospection and extraction. The only laboratory for calibration of neutron detectors in Brazil is localized at the Institute for Radioprotection and Dosimetry (IRD/CNEN), Rio de Janeiro, which is part of the IAEA SSDL network. This laboratory is the national standard laboratory in Brazil. With the increase in the demand for the calibration of neutron detectors, there is a need for another calibration services. In this context, the Calibration Laboratory of IPEN/CNEN, Sao Paulo, which already offers calibration services of radiation detectors with standard X, gamma, beta and alpha beams, has recently projected a new calibration laboratory for neutron detectors. In this work, the ambient equivalent dose rate (H⁎(10)) was evaluated in several positions inside and around this laboratory, using Monte Carlo simulation (MCNP5 code), in order to verify the adequateness of the shielding. The obtained results showed that the shielding is effective, and that this is a low-cost methodology to improve the safety of the workers and evaluate the total staff workload. (author)

  20. Zero-gravity cloud physics laboratory: Experiment program definition and preliminary laboratory concept studies

    Science.gov (United States)

    Eaton, L. R.; Greco, E. V.

    1973-01-01

    The experiment program definition and preliminary laboratory concept studies on the zero G cloud physics laboratory are reported. This program involves the definition and development of an atmospheric cloud physics laboratory and the selection and delineations of a set of candidate experiments that must utilize the unique environment of zero gravity or near zero gravity.

  1. Laboratory testing for prescription opioids.

    Science.gov (United States)

    Milone, Michael C

    2012-12-01

    Opioid analgesic misuse has risen significantly over the past two decades, and these drugs now represent the most commonly abused class of prescription medications. They are a major cause of poisoning deaths in the USA exceeding heroin and cocaine. Laboratory testing plays a role in the detection of opioid misuse and the evaluation of patients with opioid intoxication. Laboratories use both immunoassay and chromatographic methods (e.g., liquid chromatography with mass spectrometry detection), often in combination, to yield high detection sensitivity and drug specificity. Testing methods for opioids originated in the workplace-testing arena and focused on detection of illicit heroin use. Analysis for a wide range of opioids is now required in the context of the prescription opioid epidemic. Testing methods have also been primarily based upon urine screening; however, methods for analyzing alternative samples such as saliva, sweat, and hair are available. Application of testing to monitor prescription opioid drug therapy is an increasingly important use of drug testing, and this area of testing introduces new interpretative challenges. In particular, drug metabolism may transform one clinically available opioid into another. The sensitivity of testing methods also varies considerably across the spectrum of opioid drugs. An understanding of opioid metabolism and method sensitivity towards different opioid drugs is therefore essential to effective use of these tests. Improved testing algorithms and more research into the effective use of drug testing in the clinical setting, particularly in pain medicine and substance abuse, are needed.

  2. Laboratory Tests of Chameleon Models

    CERN Document Server

    Brax, Philippe; Davis, Anne-Christine; Shaw, Douglas

    2009-01-01

    We present a cursory overview of chameleon models of dark energy and their laboratory tests with an emphasis on optical and Casimir experiments. Optical experiments measuring the ellipticity of an initially polarised laser beam are sensitive to the coupling of chameleons to photons. The next generation of Casimir experiments may be able to unravel the nature of the scalar force mediated by the chameleon between parallel plates.

  3. Preliminary establishment of the laboratory diagnostic test for malignant hyperthermia%恶性高热实验室诊断方法的初步建立

    Institute of Scientific and Technical Information of China (English)

    王颖林; 郭向阳; 罗爱伦; 黄宇光; 叶铁虎; 任洪智; 谭刚; 崔旭蕾

    2008-01-01

    目的 初步建立恶性高热(MH)的实验室诊断方法-咖啡因-氟烷骨骼肌收缩试验(CHCT).方法 选取10头实验小型猪和1头皮特兰猪,肌肉注射氯胺酮和地西泮麻醉后,静脉注射硫喷妥钠5mg/kg和琥珀胆碱2mg/kg麻醉诱导后气管插管,机械通气,吸入2%~3%氟烷4 h,新鲜气流量为2 L/min,纯氧和空气各1 L/min.记录麻醉过程中及麻醉结束后48 h内MH的发生情况.气管插管后即刻取耳组织,采用常规酚氯仿方法提取基因组DNA,检测蓝尼定受体-1(RYR1)基因的突变情况.根据北美MH研究组的标准建立CHCT的实验装置,气管插管后即刻取股四头肌近肌腱部位的肌纤维,进行CHCT.结果 实验小型猪均未见MH发作,而皮特兰猪在麻醉过程中出现MH的特征性表现.RYR1基因检测显示,实验小型猪均为氟烷抗性基因型(HALNN);皮特兰猪为氟烷易感基因型(HALnn).CHCT结果表明,实验小型猪诊断为非MH易感猪,皮特兰猪诊断为MH易感猪.结论 .实验小型猪和皮特兰猪的CHCT诊断结果与特征性表现及RYR1基因检测结果均一致,初步验证本实验室CHCT设备的稳定性及测定结果的可靠性.%Objective To preliminarily establish laboratory diagnostic test for malignant hyperthermia (MH) -- caffeine and halothane contracture test (CHCT). Methods Ten Chinese experimental miniature pigs (CEMP) and one pietrain swine were selected in this study. The animals were anesthetized with ketamine and diasepam. Anesthesia was induced with thiopental sodium 5 mg/kg and tracheal intubation was facilitated with suecinylcholine 2 mg/kg intravenously. The animals were mechanically ventilated and anesthesia was maintained with inhalation of 2%-3% halothane for4 h. Frash gas flow was set at 2 L/min and oxygen and air flow at 1 L/ min. All the aninals were observed whether the MH episodes were initiated or not during the process of anesthesia and 48 h after anesthesia. Ear tissues were removed immediately after

  4. CAECC Software Testing Laboratory Accredited by CNAL

    Institute of Scientific and Technical Information of China (English)

    2005-01-01

    Software Testing Laboratory of China Aerospace Engineering and Consultation Center (CAECC) is accredited by China National Accreditation Board for Laboratories (CNAL) as the first such laboratory in domestic space industry. Since CNAL is a member of International Laboratory Accreditation Cooperation (ILAC),software testing reports certificated to CAECC are recognized by 45 laboratory accreditation organizations in AsiaPacific region, Europe and America.

  5. SENSORY AND CONSUMER TESTING LABORATORY

    Data.gov (United States)

    Federal Laboratory Consortium — These laboratories conduct a wide range of studies to characterize the sensory properties of and consumer responses to foods, beverages, and other consumer products....

  6. Educational ultrasound nondestructive testing laboratory.

    Science.gov (United States)

    Genis, Vladimir; Zagorski, Michael

    2008-09-01

    The ultrasound nondestructive evaluation (NDE) of materials course was developed for applied engineering technology students at Drexel University's Goodwin College of Professional Studies. This three-credit, hands-on laboratory course consists of two parts: the first part with an emphasis on the foundations of NDE, and the second part during which ultrasound NDE techniques are utilized in the evaluation of parts and materials. NDE applications are presented and applied through real-life problems, including calibration and use of the latest ultrasonic testing instrumentation. The students learn engineering and physical principles of measurements of sound velocity in different materials, attenuation coefficients, material thickness, and location and dimensions of discontinuities in various materials, such as holes, cracks, and flaws. The work in the laboratory enhances the fundamentals taught during classroom sessions. This course will ultimately result in improvements in the educational process ["The greater expectations," national panel report, http://www.greaterexpectations.org (last viewed February, 2008); R. M. Felder and R. Brent "The intellectual development of Science and Engineering Students. Part 2: Teaching to promote growth," J. Eng. Educ. 93, 279-291 (2004)] since industry is becoming increasingly reliant on the effective application of NDE technology and the demand on NDE specialists is increasing. NDE curriculum was designed to fulfill levels I and II NDE in theory and training requirements, according to American Society for Nondestructive Testing, OH, Recommended Practice No. SNT-TC-1A (2006).

  7. CERTS Microgrid Laboratory Test Bed

    Energy Technology Data Exchange (ETDEWEB)

    Lasseter, R. H.; Eto, J. H.; Schenkman, B.; Stevens, J.; Volkmmer, H.; Klapp, D.; Linton, E.; Hurtado, H.; Roy, J.

    2010-06-08

    CERTS Microgrid concept captures the emerging potential of distributed generation using a system approach. CERTS views generation and associated loads as a subsystem or a 'microgrid'. The sources can operate in parallel to the grid or can operate in island, providing UPS services. The system can disconnect from the utility during large events (i.e. faults, voltage collapses), but may also intentionally disconnect when the quality of power from the grid falls below certain standards. CERTS Microgrid concepts were demonstrated at a full-scale test bed built near Columbus, Ohio and operated by American Electric Power. The testing fully confirmed earlier research that had been conducted initially through analytical simulations, then through laboratory emulations, and finally through factory acceptance testing of individual microgrid components. The islanding and resynchronization method met all Institute of Electrical and Electronics Engineers Standard 1547 and power quality requirements. The electrical protection system was able to distinguish between normal and faulted operation. The controls were found to be robust under all conditions, including difficult motor starts and high impedance faults.

  8. Anthropomorphic Test Drive (ATD) Certification Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — The ATD Certification Laboratory consists of several test fixtures to ensure ATDs are functioning correctly and within specifications prior to use in any OP testing....

  9. Putting New Laboratory Tests Into Practice

    Science.gov (United States)

    ... Home Visit Global Sites Search Help? Putting New Laboratory Tests into Practice Share this page: Was this ... of articles that describe how different types of laboratory tests are developed, validated, and made available for ...

  10. CERTS Microgrid Laboratory Test Bed

    Energy Technology Data Exchange (ETDEWEB)

    Eto, Joe; Lasseter, Robert; Schenkman, Ben; Stevens, John; Klapp, Dave; Volkommer, Harry; Linton, Ed; Hurtado, Hector; Roy, Jean

    2009-06-18

    The objective of the CERTS Microgrid Test Bed project was to enhance the ease of integrating energy sources into a microgrid. The project accomplished this objective by developing and demonstrating three advanced techniques, collectively referred to as the CERTS Microgrid concept, that significantly reduce the level of custom field engineering needed to operate microgrids consisting of generating sources less than 100kW. The techniques comprising the CERTS Microgrid concept are: 1) a method for effecting automatic and seamless transitions between grid-connected and islanded modes of operation, islanding the microgrid's load from a disturbance, thereby maintaining a higher level of service, without impacting the integrity of the utility's electrical power grid; 2) an approach to electrical protection within a limited source microgrid that does not depend on high fault currents; and 3) a method for microgrid control that achieves voltage and frequency stability under islanded conditions without requiring high-speed communications between sources. These techniques were demonstrated at a full-scale test bed built near Columbus, Ohio and operated by American Electric Power. The testing fully confirmed earlier research that had been conducted initially through analytical simulations, then through laboratory emulations,and finally through factory acceptance testing of individual microgrid components. The islanding and resychronization method met all Institute of Electrical and Electronics Engineers Standard 1547 and power quality requirements. The electrical protection system was able to distinguish between normal and faulted operation. The controls were found to be robust under all conditions, including difficult motor starts and high impedance faults. The results from these tests are expected to lead to additional testing of enhancements to the basic techniques at the test bed to improve the business case for microgrid technologies, as well to field

  11. Deep Underground Science and Engineering Laboratory - Preliminary Design Report

    CERN Document Server

    Lesko, Kevin T; Alonso, Jose; Bauer, Paul; Chan, Yuen-Dat; Chinowsky, William; Dangermond, Steve; Detwiler, Jason A; De Vries, Syd; DiGennaro, Richard; Exter, Elizabeth; Fernandez, Felix B; Freer, Elizabeth L; Gilchriese, Murdock G D; Goldschmidt, Azriel; Grammann, Ben; Griffing, William; Harlan, Bill; Haxton, Wick C; Headley, Michael; Heise, Jaret; Hladysz, Zbigniew; Jacobs, Dianna; Johnson, Michael; Kadel, Richard; Kaufman, Robert; King, Greg; Lanou, Robert; Lemut, Alberto; Ligeti, Zoltan; Marks, Steve; Martin, Ryan D; Matthesen, John; Matthew, Brendan; Matthews, Warren; McConnell, Randall; McElroy, William; Meyer, Deborah; Norris, Margaret; Plate, David; Robinson, Kem E; Roggenthen, William; Salve, Rohit; Sayler, Ben; Scheetz, John; Tarpinian, Jim; Taylor, David; Vardiman, David; Wheeler, Ron; Willhite, Joshua; Yeck, James

    2011-01-01

    The DUSEL Project has produced the Preliminary Design of the Deep Underground Science and Engineering Laboratory (DUSEL) at the rehabilitated former Homestake mine in South Dakota. The Facility design calls for, on the surface, two new buildings - one a visitor and education center, the other an experiment assembly hall - and multiple repurposed existing buildings. To support underground research activities, the design includes two laboratory modules and additional spaces at a level 4,850 feet underground for physics, biology, engineering, and Earth science experiments. On the same level, the design includes a Department of Energy-shepherded Large Cavity supporting the Long Baseline Neutrino Experiment. At the 7,400-feet level, the design incorporates one laboratory module and additional spaces for physics and Earth science efforts. With input from some 25 science and engineering collaborations, the Project has designed critical experimental space and infrastructure needs, including space for a suite of multi...

  12. Geotechnical Design Asssisted by Laboratory Testing

    DEFF Research Database (Denmark)

    Foged, Niels; Dysli, Michel; Head, Ken H.;

    1997-01-01

    Eurocode 7 Part 2 is intended to serve as a reference document for the use of laboratory tests for geotechnical design. It covers the execution and interpretation of the most commonly used laboratory tests. The standard aims at ensuring that adequate quality is reached in the execution...... of laboratory tests and their interpretation. Within the framework of European Standardisation, Eurocode 7 Part 1 on the design of geotechnical structures was established. Complementary, Eurocode 7 Part 3 addresses field testing....

  13. Helium at White Dwarf Photospheric Conditions: Preliminary Laboratory Results

    Science.gov (United States)

    Schaeuble, M.; Falcon, R. E.; Gomez, T. A.; Winget, D. E.; Montgomery, M. H.; Bailey, J. E.

    2017-03-01

    We present preliminary results of an experimental study exploring helium at photospheric conditions of white dwarf stars. These data were collected at Sandia National Laboratories' Z-machine, the largest x-ray source on earth. Our helium results could have many applications ranging from validating current DB white dwarf model atmospheres to providing accurate He pressure shifts at varying temperatures and densities. In a much broader context, these helium data can be used to guide theoretical developments in new continuum-lowering models for two-electron atoms. We also discuss future applications of our updated experimental design, which enables us to sample a greater range of densities, temperatures, and gas compositions.

  14. Helium at white dwarf photospheric conditions: preliminary laboratory results

    CERN Document Server

    Schaeuble, Marc; Gomez, Thomas A; Winget, Don E; Montgomery, Michael H; Bailey, James E

    2016-01-01

    We present preliminary results of an experimental study exploring helium at photospheric conditions of white dwarf stars. These data were collected at Sandia National Laboratories' Z-machine, the largest x-ray source on earth. Our helium results could have many applications ranging from validating current DB white dwarf model atmospheres to providing accurate He pressure shifts at varying temperatures and densities. In a much broader context, these helium data can be used to guide theoretical developments in new continuum-lowering models for two-electron atoms. We also discuss future applications of our updated experimental design, which enables us to sample a greater range of densities, temperatures, and gas compositions.

  15. Environmental Survey preliminary report, Ames Laboratory, Ames, Iowa

    Energy Technology Data Exchange (ETDEWEB)

    1989-03-01

    This report presents the preliminary findings of the first phase of the environmental Survey of the United States Department of Energy's (DOE) Ames Laboratory, conducted April 18 through 22, 1988. The Survey is being conducted by an interdisciplinary team of environmental specialists, led and managed by the Office of Environment, Safety and Health's Office of Environmental Audit. Individual team members are being supplied by private contractors. The objective of the Survey is to identify environmental problems and areas of environmental risk associated with the Ames Laboratory. The Survey covers all environmental media and all areas of environmental regulation. It is being performed in accordance with the DOE Environmental Survey Manual. This phase of the Survey involves the review of existing site environmental data, observations of the operations carried on at the Ames Laboratory, and interviews with site personnel. The Survey team developed a Sampling and Analysis (S A) Plan to assist in further assessing certain of the environmental problems identified during its on-site activities. The S A plan is being developed by the Idaho National Engineering Laboratory. When S A is completed, the results will be incorporated into the Ames Laboratory Environmental Survey findings for inclusion in the Environmental Survey Summary Report. 60 refs., 13 figs., 20 tabs.

  16. Postirradiation Testing Laboratory (327 Building)

    Energy Technology Data Exchange (ETDEWEB)

    Kammenzind, D.E.

    1997-05-28

    A Standards/Requirements Identification Document (S/RID) is the total list of the Environment, Safety and Health (ES and H) requirements to be implemented by a site, facility, or activity. These requirements are appropriate to the life cycle phase to achieve an adequate level of protection for worker and public health and safety, and the environment during design, construction, operation, decontamination and decommissioning, and environmental restoration. S/RlDs are living documents, to be revised appropriately based on change in the site`s or facility`s mission or configuration, a change in the facility`s life cycle phase, or a change to the applicable standards/requirements. S/RIDs encompass health and safety, environmental, and safety related safeguards and security (S and S) standards/requirements related to the functional areas listed in the US Department of Energy (DOE) Environment, Safety and Health Configuration Guide. The Fluor Daniel Hanford (FDH) Contract S/RID contains standards/requirements, applicable to FDH and FDH subcontractors, necessary for safe operation of Project Hanford Management Contract (PHMC) facilities, that are not the direct responsibility of the facility manager (e.g., a site-wide fire department). Facility S/RIDs contain standards/requirements applicable to a specific facility that are the direct responsibility of the facility manager. S/RlDs are prepared by those responsible for managing the operation of facilities or the conduct of activities that present a potential threat to the health and safety of workers, public, or the environment, including: Hazard Category 1 and 2 nuclear facilities and activities, as defined in DOE 5480.23. Selected Hazard Category 3 nuclear, and Low Hazard non-nuclear facilities and activities, as agreed upon by RL. The Postirradiation Testing Laboratory (PTL) S/RID contains standards/ requirements that are necessary for safe operation of the PTL facility, and other building/areas that are the direct

  17. Development of e-Juba, a preliminary proof of concept unmanned aerial vehicle designed to facilitate the transportation of microbiological test samples from remote rural clinics to National Health Laboratory Service laboratories.

    Science.gov (United States)

    Mendelow, B; Muir, P; Boshielo, B T; Robertson, J

    2007-11-01

    For students and academics within the field of Medical Microbiology and Infectious Diseases, it is readily apparent what an enormous professional contribution Professor Hendrik Koornhof has made to this critically important specialty, not only in Africa, but worldwide. For those outside of the specialty, his contributions as a thoroughly decent person and role model are no less evident. What emerges in both spheres is his clear commitment to the welfare of others, as opposed to himself. His modesty and self-effacing nature have endeared Hendrik to many generations of students, peers and others who have indeed been privileged to have benefited from knowing him and working with him. In his 50 years with the South African Institute for Medical Research, and subsequently with the National Health Laboratory Service, Hendrik Koornhof has been the ideal academic, who is not as concerned about receiving financial rewards, recognition, etc. as about contributing to scientific knowledge. Many of his contributions have been in guiding others by his words and his deeds, and as a result he has been rewarded in seeing the accomplishments of his students, many of whom have gone on to achieve greatness in diverse fields, both locally and abroad. As we reflect in this festschrift on Hendrik's many achievements over 80 years, we thank him for more than just his research and teaching contributions over half a century with the South African Institute for Medical Research and the National Health Laboratory Service. We thank him for showing us what a privilege it is to work in the world of academia. Although we are not microbiologists, we thank him for having inspired us with the will to address problems of service delivery in the fight against microbiological diseases, which constitute the overwhelming bulk of the burden of disease in the developing world, both in Africa and further afield.

  18. Federal laboratory nondestructive testing research and development applicable to industry

    Energy Technology Data Exchange (ETDEWEB)

    Smith, S.A.; Moore, N.L.

    1987-02-01

    This document presents the results of a survey of nondestructive testing (NDT) and related sensor technology research and development (R and D) at selected federal laboratories. Objective was to identify and characterize NDT activities that could be applied to improving energy efficiency and overall productivity in US manufacturing. Numerous federally supported R and D programs were identified in areas such as acoustic emissions, eddy current, radiography, computer tomography and ultrasonics. A Preliminary Findings Report was sent to industry representatives, which generated considerable interest.

  19. 21 CFR 640.67 - Laboratory tests.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 7 2010-04-01 2010-04-01 false Laboratory tests. 640.67 Section 640.67 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) BIOLOGICS ADDITIONAL STANDARDS FOR HUMAN BLOOD AND BLOOD PRODUCTS Source Plasma § 640.67 Laboratory tests. Each unit...

  20. Environmental Survey preliminary report, Argonne National Laboratory, Argonne, Illinois

    Energy Technology Data Exchange (ETDEWEB)

    1988-11-01

    This report presents the preliminary findings of the first phase of the Environmental Survey of the United States Department of Energy's (DOE) Argonne National Laboratory (ANL), conducted June 15 through 26, 1987. The Survey is being conducted by an interdisciplinary team of environmental specialists, led and managed by the Office of Environment, Safety and Health's Office of Environmental Audit. The team includes outside experts supplied by a private contractor. The objective of the Survey is to identify environmental problems and areas of environmental risk associated with ANL. The Survey covers all environmental media and all areas of environmental regulation. It is being performed in accordance with the DOE Environmental Survey Manual. The on-site phase of the Survey involves the review of existing site environmental data, observations of the operations carried on at ANL, and interviews with site personnel. The Survey team developed a Sampling and Analysis (S A) Plan to assist in further assessing certain of the environmental problems identified during its on-site activities. The S A Plan will be executed by the Oak Ridge National Laboratory (ORNL). When completed, the S A results will be incorporated into the Argonne National Laboratory Environmental Survey findings for inclusion in the Environmental Survey Summary Report. 75 refs., 24 figs., 60 tabs.

  1. How Reliable Is Laboratory Testing?

    Science.gov (United States)

    Advertisement Proceeds from website advertising help sustain Lab Tests Online. AACC is a not-for-profit organization and does not endorse non-AACC products and services. Advertising & Sponsorship: Policy | Opportunities ...

  2. Environmental Survey preliminary report, Fermi National Accelerator Laboratory, Batavia, Illinois

    Energy Technology Data Exchange (ETDEWEB)

    1988-10-01

    This report presents the preliminary findings from the first phase of the Environmental Survey of the US Department of Energy (DOE) Fermi National Accelerator Laboratory (Fermilab), conducted September 14 through 25, 1987. The Survey is being conducted by an interdisciplinary team of environmental specialists led and managed by the Office of Environment, Safety and Health's Office of Environmental Audit. Individual participants for the Survey team are being supplied by a private contractor. The objective of the Survey is to identify environmental problems and areas of environmental risk associated with Fermilab. The Survey covers all environmental media and all areas of environmental regulation. It is being performed in accordance with the DOE Environmental Survey Manual. This phase of the Survey involves the review of existing site environmental data, observations of the operations performed at Fermilab, and interviews with site personnel. 110 refs., 26 figs., 41 tabs.

  3. Laboratory testing for platelet function disorders.

    Science.gov (United States)

    Israels, S J

    2015-05-01

    Platelet function testing is both complex and labor intensive. A stepwise approach to the evaluation of patients with suspected platelet disorders will optimize the use of laboratory resources, beginning with an appropriate clinical evaluation to determine whether the bleeding is consistent with a defect of primary hemostasis. Bleeding assessment tools, evaluation of platelet counts, and review of peripheral blood cell morphology can aid the initial assessment. For patients requiring further laboratory testing, platelet aggregometry, secretion assays, and von Willebrand factor assays are the most useful next steps and will direct further specialized testing including flow cytometry, electron microscopy, and molecular diagnostics. Guidelines and recommendations for standardizing platelet function testing, with a particular focus on light transmission aggregometry, are available and can provide a template for clinical laboratories in establishing procedures that will optimize diagnosis and assure quality results. This review outlines an approach to platelet function testing and reviews testing methods available to clinical laboratories.

  4. Preliminary Results of Field Emission Cathode Tests

    Science.gov (United States)

    Sovey, James S.; Kovaleski, Scott D.

    2001-01-01

    Preliminary screening tests of field emission cathodes such as chemical vapor deposited (CVD) diamond, textured pyrolytic graphite, and textured copper were conducted at background pressures typical of electric thruster test facilities to assess cathode performance and stability. Very low power electric thrusters which provide tens to hundreds micronewtons of thrust may need field emission neutralizers that have a capability of tens to hundreds of microamperes. From current voltage characteristics, it was found that the CVD diamond and textured metals cathodes clearly satisfied the Fowler-Nordheim emission relation. The CVD diamond and a textured copper cathode had average current densities of 270 and 380 mA/sq cm, respectively, at the beginning-of-life. After a few hours of operation the cathode emission currents degraded by 40 to 75% at background pressures in the 10(exp -5) Pa to 10(exp -4) Pa range. The textured pyrolytic graphite had a modest current density at beginning-of-life of 84 mA/sq cm, but this cathode was the most stable of all. Extended testing of the most promising cathodes is warranted to determine if current degradation is a burn-in effect or whether it is a long-term degradation process. Preliminary experiments with ferroelectric emission cathodes, which are ceramics with spontaneous electric polarization, were conducted. Peak current densities of 30 to 120 mA/sq cm were obtained for pulse durations of about 500 ns in the 10(exp -4) Pa pressure range.

  5. Grid Modernization Laboratory Consortium - Testing and Verification

    Energy Technology Data Exchange (ETDEWEB)

    Kroposki, Benjamin; Skare, Paul; Pratt, Rob; Kim, Tom; Ellis, Abraham

    2017-05-11

    This paper highlights some of the unique testing capabilities and projects being performed at several national laboratories as part of the U. S. Department of Energy Grid Modernization Laboratory Consortium. As part of this effort, the Grid Modernization Laboratory Consortium Testing Network isbeing developed to accelerate grid modernization by enablingaccess to a comprehensive testing infrastructure and creating a repository of validated models and simulation tools that will be publicly available. This work is key to accelerating thedevelopment, validation, standardization, adoption, and deployment of new grid technologies to help meet U. S. energy goals.

  6. Environmental Survey preliminary report, Lawrence Livermore National Laboratory, Livermore, California

    Energy Technology Data Exchange (ETDEWEB)

    1987-12-01

    This report presents the preliminary findings from the first phase of the Environmental Survey of the Department of Energy (DOE) Lawrence Livermore National Laboratory (LLNL), conducted December 1 through 19, 1986. The Survey is being conducted by an interdisciplinary team of environmental specialists, led and managed by the Office of Environment, Safety and Health's Office of Environmental Audit. Individual team components are being supplied by a private contractor. The objective of the Survey is to identify environmental problems and areas of environmental risk associated with LLNL. The Survey covers all environmental media all areas of environmental regulation. It is being performed in accordance with the DOE Environmental Survey Manual. This phase of the Survey involves the review of existing site environmental data, observations of the operations performed at LLNL, and interviews with site personnel. A Sampling and Analysis Plan was developed to assist in further assessing certain of the environmental problems identified during performance of on-site activities. The Sampling and Analysis Plan will be executed by a DOE National Laboratory. When completed, the results will be incorporated into the LLNL Environmental Survey Interim Report. The Interim Report will reflect the final determinations of the LLNL Survey. 70 refs., 58 figs., 52 tabs.,

  7. Environmental Survey preliminary report, Brookhaven National Laboratory, Upton, New York

    Energy Technology Data Exchange (ETDEWEB)

    1988-06-01

    This report presents the preliminary findings from the first phase of the Environmental Survey of the United States Department of Energy (DOE) Brookhaven National Laboratory (BNL) conducted April 6 through 17, 1987. The Survey is being conducted by an interdisciplinary team of environmental specialists, led and managed by the Office of Environment, Safety and Health's Office of Environmental Audit. Individual team components are being supplied by a private contractor. The objective of the Survey is to identify environmental problems and areas of environmental risk associated with BNL. The Survey covers all environmental media and all areas of environmental regulation. It is being performed in accordance with the DOE Environmental Survey Manual. This phase of the Survey involves the review of existing site environmental data, observations of the operations carried on at BNL, and interviews with site personnel. The Survey team developed a Sampling and Analysis Plan to assist in further assessing specific environmental problems identified during its on-site activities. The Sampling and Analysis Plan will be executed by Oak Ridge National Laboratory. When completed, the results will be incorporated into the BNL Environmental Survey Interim Report. The Interim Report will reflect the final determinations of the BNL Survey. 80 refs., 24 figs., 48 tabs.

  8. Laboratory Investigations on Estuary Salinity Mixing: Preliminary Analysis

    Directory of Open Access Journals (Sweden)

    F. H. Nuryazmeen

    2014-05-01

    Full Text Available Estuaries are bodies of water along the coasts that are formed when fresh water from rivers flows into and mixes with salt water from the ocean. The estuaries serve as a habitat to some aquatic lives, including mangroves. Human-induced activities such as dredging of shipping lanes along the bottom estuarine, the disposal of industrial wastes into the water system and shoreline development influence estuarine dynamics which include mixing process. These activities might contribute to salinity changes and further adversely affect the estuarine ecosystem. In order to study at the characteristics of the mixing between salt water (estuary and freshwater (river, a preliminary investigation had been done in the laboratory. Fresh water was released from one end of the flume and overflowing at weir at the other end. Meanwhile, salt water was represented by the red dye tracer released through a weir and intruded upstream as a gravity current. The isohalines are plotted to see the salinity patterns. Besides, to examine the spatial and temporal salinity profiles along the laboratory investigations, the plotted graphs have been made. The results show that the changes in salinity level along the flume due to mixing between fresh water and salt water. This showed typical salt-wedge estuary characteristics.

  9. 10 CFR 431.18 - Testing laboratories.

    Science.gov (United States)

    2010-01-01

    ... 10 Energy 3 2010-01-01 2010-01-01 false Testing laboratories. 431.18 Section 431.18 Energy DEPARTMENT OF ENERGY ENERGY CONSERVATION ENERGY EFFICIENCY PROGRAM FOR CERTAIN COMMERCIAL AND INDUSTRIAL... supplements NIST Handbook 150, National Voluntary Laboratory Accreditation Program Procedures and...

  10. Laboratory Test Setup for Cyclic Axially Loaded Piles in Sand

    DEFF Research Database (Denmark)

    Thomassen, Kristina; Ibsen, Lars Bo; Andersen, Lars Vabbersgaard

    2017-01-01

    conditions for all tests. For verifications purposes six static tension tests conducted at three different vertical effective stress levels of 0, 35 and 70 kPa. The load-displacement curves showed that the test setup provides repeatable test results. A preliminary comparison between the unit shaft friction......This paper presents a comprehensive description and the considerations regarding the design of a new laboratory test setup for testing cyclic axially loaded piles in sand. The test setup aims at analysing the effect of axial one-way cyclic loading on pile capacity and accumulated displacements....... Another aim was to test a large diameter pile segment with dimensions resembling full-scale piles to model the interface properties between pile and sand correctly. The pile segment was an open-ended steel pipe pile with a diameter of 0.5 m and a length of 1 m. The sand conditions resembled the dense sand...

  11. CERTS Microgrid Laboratory Test Bed

    Energy Technology Data Exchange (ETDEWEB)

    ETO, J.; LASSETER, R.; SCHENKMAN, B.; STEVENS, J.; KLAPP, D.; VOLKOMMER, H.; LINTON, E.; HURTADO, H.; ROY, J.

    2010-06-08

    The objective of the CERTS Microgrid Test Bed project was to enhance the ease of integrating energy sources into a microgrid. The project accomplished this objective by developing and demonstrating three advanced techniques, collectively referred to as the CERTS Microgrid concept, that significantly reduce the level of custom field engineering needed to operate microgrids consisting of generating sources less than 100kW. The techniques comprising the CERTS Microgrid concept are: 1 a method for effecting automatic and seamless transitions between grid-connected and islanded modes of operation, islanding the microgrid's load from a disturbance, thereby maintaining a higher level of service, without impacting the integrity of the utility's electrical power grid; 2 an approach to electrical protection within a limited source microgrid that does not depend on high fault currents; and 3 a method for microgrid control that achieves voltage and frequency stability under islanded conditions without requiring high-speed communications between sources.

  12. Environmental Survey preliminary report, Sandia National Laboratories, Livermore, California

    Energy Technology Data Exchange (ETDEWEB)

    1988-01-01

    This report contains the preliminary findings based on the first phase of an Environmental Survey at the Department of Energy (DOE) Sandia National Laboratories Livermore (SNLL), located at Livermore, California. The Survey is being conducted by DOE's Office of Environment, Safety and Health. The SNLL Survey is a portion of the larger, comprehensive DOE Environmental Survey encompassing all major operating facilities of DOE. The DOE Environmental Survey is one of a series of initiatives announced on September 18, 1985, by Secretary of Energy, John S. Herrington, to strengthen the environmental, safety, and health programs and activities within DOE. The purpose of the Environmental Survey is to identify, via a no fault'' baseline Survey of all the Department's major operating facilities, environmental problems and areas of environmental risk. The identified problem areas will be prioritized on a Department-wide basis in order of importance in 1989. The findings in this report are subject to modification based on the results from the Sampling and Analysis Phase of the Survey. The findings are also subject to modification based on comments from the Albuquerque Operations Office concerning the technical accuracy of the findings. The modified preliminary findings and any other appropriate changes will be incorporated into an Interim Report. The Interim Report will serve as the site-specific source for environmental information generated by the Survey, and ultimately as the primary source of information for the DOE-wide prioritization of environmental problems in the Survey Summary Report. 43 refs., 21 figs., 24 tabs.

  13. Solar Stirling power generation - Systems analysis and preliminary tests

    Science.gov (United States)

    Selcuk, M. K.; Wu, Y.-C.; Moynihan, P. I.; Day, F. D., III

    1977-01-01

    The feasibility of an electric power generation system utilizing a sun-tracking parabolic concentrator and a Stirling engine/linear alternator is being evaluated. Performance predictions and cost analysis of a proposed large distributed system are discussed. Design details and preliminary test results are presented for a 9.5 ft diameter parabolic dish at the Jet Propulsion Laboratory (Caltech) Table Mountain Test Facility. Low temperature calorimetric measurements were conducted to evaluate the concentrator performance, and a helium flow system is being used to test the solar receiver at anticipated working fluid temperatures (up to 650 or 1200 C) to evaluate the receiver thermal performance. The receiver body is designed to adapt to a free-piston Stirling engine which powers a linear alternator assembly for direct electric power generation. During the next phase of the program, experiments with an engine and receiver integrated into the concentrator assembly are planned.

  14. Environmental Survey preliminary report, Lawrence Berkeley Laboratory, Berkeley, California

    Energy Technology Data Exchange (ETDEWEB)

    1988-07-01

    The purpose of this report is to present the preliminary findings made during the Environmental Survey, February 22--29, 1988, at the US Department of Energy (DOE) Lawrence Berkeley Laboratory (LBL) in Berkeley, California. The University of California operates the LBL facility for DOE. The LBL Survey is part of the larger DOE-wide Environmental Survey announced by Secretary John S. Herrington on September 18, 1985. The purpose of this effort is to identify, via no fault'' baseline Surveys, existing environmental problems and areas of environmental risk at DOE facilities, and to rank them on a DOE wide basis. This ranking will enable DOE to more effectively establish priorities for addressing environmental problems and allocate the resources necessary to correct them. Because the Survey is no fault'' and is not an audit,'' it is not designed to identify specific isolated incidents of noncompliance or to analyze environmental management practices. Such incidents and/or management practices will, however, be used in the Survey as a means of identifying existing and potential environmental problems. The LBL Survey was conducted by a multidisciplinary team of technical specialists headed and managed by a Team Leader and Assistant Team Leader from DOE's Office of Environmental Audit. A complete list of the LBL Survey participants and their affiliations is provided in Appendix A. 80 refs., 27 figs., 37 tabs.

  15. Fatigue Sensor Evaluation Program Laboratory Test Report.

    Science.gov (United States)

    1975-10-01

    Evaluation Program - laboratory Test Report, " by John Y. Kaufman, Design Engineer, and it was prepared for publication by Sue Bardsley, Technical Aid ...fatigue sensor as an aid to this purpose. The laboratory test effort was based on collection of data from six types of tests and thirty-three...34 ’: « •IIIS ......... li : « rtrtintr : •* M» c f M i H ::::::;:• ;:« ...j . .... ..:. •f’ ::.::::: ^::|:::: n» VH ft;; ** ViH ! * 1 - •• •-•• ; i

  16. Hereditary red cell membrane disorders and laboratory diagnostic testing.

    Science.gov (United States)

    King, M-J; Zanella, A

    2013-06-01

    This overview describes two groups of nonimmune hereditary hemolytic anemias caused by defects in membrane proteins located in distinct layers of the red cell membrane. Hereditary spherocytosis (HS), hereditary elliptocytosis (HE), and hereditary pyropoikilocytosis (HPP) represent disorders of the red cell cytoskeleton. Hereditary stomatocytoses represents disorders of cation permeability in the red cell membrane. The current laboratory screening tests for HS are the osmotic fragility test, acid glycerol lysis time test (AGLT), cryohemolysis test, and eosin-5'-maleimide (EMA)-binding test. For atypical HS, SDS-polyacrylamide gel electrophoresis of erythrocyte membrane proteins is carried out to confirm the diagnosis. The diagnosis of HE/HPP is based on abnormal red cell morphology and the detection of protein 4.1R deficiency or spectrin variants using gel electrophoresis. None of screening tests can detect all HS cases. Some testing centers (a survey of 25 laboratories) use a combination of tests (e.g., AGLT and EMA). No specific screening test for hereditary stomatocytoses is available. The preliminary diagnosis is based on presenting a compensated hemolytic anemia, macrocytosis, and a temperature or time dependent pseudohyperkalemia in some patients. Both the EMA-binding test and the osmotic fragility test may help in differential diagnosis of HS and hereditary stomatocytosis.

  17. Preliminary test results for the SVX4

    Energy Technology Data Exchange (ETDEWEB)

    Christofek, L.; Hanagaki, K.; Rapidis, P.; Utes, M.; /Fermilab

    2005-06-01

    We present and summarize the preliminary test results for SVX4 chip testing. There are presently two versions of the SVX4. Version 2 has on-chip bypassing and Version 1 does not. The on-chip bypassing is a layer of transistors under the front-end analog pipeline that acts as a bypassing capacitor for the voltage supply. Its size is about a microfarad. We aggressively choose to test Version 2 because of this feature. The feature is advantageous for hybrid design because it eliminates the need for an additional passive component on the hybrid itself by placing it on the actual SVX4 die. Also, the SVX4 was designed to operate in two modes: D. and CDF. One can set which mode the chip will operate by placing a jumper in the proper position on the SVX4 chip carrier. In either mode, the chip can either use the operating parameters from the shift register or the shadow register. Similarly, this is selected by placing a jumper on the SVX4 chip carrier. This chip has this feature because it was unknown whether the new design of the shadow register would be operable. The shadow register is also call the SEU register or Single Event Upset register. An introduction into the functionality of the chip and an explanation on the difference between D. and CDF mode can be found in the SVX4 User's Manual [1].

  18. Preliminary Feasibility Testing of the BRIC Brine Water Recovery Concept

    Science.gov (United States)

    Callahan, Michael R.; Pensinger, Stuart; Pickering, Karen D.

    2011-01-01

    The Brine Residual In-Containment (BRIC) concept was developed as a new technology to recover water from spacecraft wastewater brines. Such capability is considered critical to closing the water loop and achieving a sustained human presence in space. The intention of the BRIC concept is to increase the robustness and efficiency of the dewatering process by performing drying inside the container used for the final disposal of the residual brine solid. Recent efforts in the development of BRIC have focused on preliminary feasibility testing using a laboratory- assembled pre-prototype unit. Observations of the drying behavior of actual brine solutions processed under BRIC-like conditions has been of particular interest. To date, experiments conducted with three types of analogue spacecraft wastewater brines have confirmed the basic premise behind the proposed application of in-place drying for these solutions. Specifically, the dried residual mass from these solutions have tended to exhibit characteristics of adhesion and flow that are expected to continue to challenge process stream management in spacecraft brine dewatering system designs. Yet, these same characteristics may favor the development of capillary- and surface-tension-based approaches envisioned as part of an ultimate microgravity-compatible BRIC design. In addition, preliminary feasibility testing of the BRIC pre-prototype confirmed that high rates of water recovery, up to 98% of the available brine water, may be possible while still removing the majority of the brine contaminants from the influent brine stream. These and other observations from testing are reported.

  19. GeoLab—A habitat-based laboratory for preliminary examination of geological samples

    Science.gov (United States)

    Evans, Cynthia A.; Calaway, Michael J.; Sue Bell, Mary; Young, Kelsey E.

    2013-10-01

    GeoLab is a prototype geological laboratory designed for deployment and testing during NASA's analog demonstrations. Scientists at NASA's Johnson Space Center (JSC) built GeoLab as part of a technology project to support the development of science operational concepts for future planetary surface missions. It was integrated into NASA's Habitat Demonstration Unit 1 - Pressurized Excursion Module (HDU1-PEM), a first generation exploration habitat test bed. As a test bed, GeoLab provides a high fidelity working space for crewmembers to perform preliminary examination and characterization of geologic samples. The GeoLab concept builds from the hardware and cleanroom protocols used in JSC's Astromaterials Sample Curation laboratories. The main hardware component of the GeoLab is a custom-built glovebox, constructed from stainless steel and polycarbonate, and built to provide a positive pressure nitrogen environment. The glovebox is mounted onto the habitat's structural ribs; the unique shape (trapezoidal prism) fits within a pie-shaped section of the cylindrical habitat. A key innovation of GeoLab is the mechanism for transferring samples into the glovebox: three antechambers (airlocks) that pass through the shell of the habitat. These antechambers allow geologic samples to enter and exit the main glovebox chamber directly from (and to) the outside, thereby controlling contamination from inside the habitat. The glovebox is configured to include imaging systems, instrumentation, and computer controls. The first field trials tested a simple configuration including a microscope, a commercially available handheld X-ray Fluorescence instrument, network cameras, and simple sample handling tools inside the glovebox. We present results from the initial field trials of GeoLab during the 2010 Desert Research and Technology Studies (Desert RATS) planetary analog test near Flagstaff, AZ. These field tests examined the general operations of the GeoLab hardware and the crew

  20. [Laboratory tests for parasitic diseases in Israel].

    Science.gov (United States)

    Marva, Esther; Grossman, Tamar

    2010-09-01

    Microscopic examination is still considered the gold standard for the diagnosis of parasitic diseases. In many clinical laboratories in hospitals and in health maintenance organizations ("Kupot Holim"), an excellent microscopic identification of parasites is performed. Microscopic examinations using wet mount preparations are performed for the detection of protozoan trophozoites and helmintic ova or larvae. Specific concentration techniques, including flotation and sedimentation procedures are further performed for the diagnosis of parasitic diseases. However, microscopic examinations are time-consuming, non-sensitive and not always reliable. Furthermore, the diagnosis of certain infections is not always possible by searching for the parasites in host tissues or excreta since risky invasive techniques might be necessary to locate the parasites. Detection of antibodies can be very useful as an indication for infection with a specific parasite, especially in individuals with no exposure to the parasite prior to recent travel in a disease-endemic area. In addition to serology, there are other tests of high sensitivity which can be integrated with microscopy, such as antigen detection in stool and blood samples as well as the use of other molecular diagnosis methods. There are two main laboratories in Israel where parasitic diagnosis is available by integration of microscopy, serology, antigen detection and molecular methods: The Reference Laboratory for Parasitology in Jerusalem at the Central Laboratories of the Ministry of Health (MOH) and the Laboratory of Parasitology at Soroka University Medical Center, Beer Sheva (SOR). There are also two special diagnostic units, one responsible for the identification of toxopLasma: Reference Laboratory for Toxoplasmosis, Public Health Laboratory, Ministry of Health, Tel Aviv (Tox), and the other for the identification of Leishmaniasis: Kuvin Center, Faculty of Medicine, Hebrew University of Jerusalem (Kuv). This article

  1. 7 CFR 75.43 - Laboratory testing.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 3 2010-01-01 2010-01-01 false Laboratory testing. 75.43 Section 75.43 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Standards... AND CERTIFICATION OF QUALITY OF AGRICULTURAL AND VEGETABLE SEEDS Fees and Charges § 75.43...

  2. Advanced Materials Laboratory User Test Planning Guide

    Science.gov (United States)

    Orndoff, Evelyne

    2012-01-01

    Test process, milestones and inputs are unknowns to first-time users of the Advanced Materials Laboratory. The User Test Planning Guide aids in establishing expectations for both NASA and non-NASA facility customers. The potential audience for this guide includes both internal and commercial spaceflight hardware/software developers. It is intended to assist their test engineering personnel in test planning and execution. Material covered includes a roadmap of the test process, roles and responsibilities of facility and user, major milestones, facility capabilities, and inputs required by the facility. Samples of deliverables, test article interfaces, and inputs necessary to define test scope, cost, and schedule are included as an appendix to the guide.

  3. Iowa Central Quality Fuel Testing Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Heach, Don; Bidieman, Julaine

    2013-09-30

    The objective of this project is to finalize the creation of an independent quality fuel testing laboratory on the campus of Iowa Central Community College in Fort Dodge, Iowa that shall provide the exploding biofuels industry a timely and cost-effective centrally located laboratory to complete all state and federal fuel and related tests that are required. The recipient shall work with various state regulatory agencies, biofuel companies and state and national industry associations to ensure that training and testing needs of their members and American consumers are met. The recipient shall work with the Iowa Department of Ag and Land Stewardship on the development of an Iowa Biofuel Quality Standard along with the Development of a standard that can be used throughout industry.

  4. Extracting laboratory test information from biomedical text

    Directory of Open Access Journals (Sweden)

    Yanna Shen Kang

    2013-01-01

    Full Text Available Background: No previous study reported the efficacy of current natural language processing (NLP methods for extracting laboratory test information from narrative documents. This study investigates the pathology informatics question of how accurately such information can be extracted from text with the current tools and techniques, especially machine learning and symbolic NLP methods. The study data came from a text corpus maintained by the U.S. Food and Drug Administration, containing a rich set of information on laboratory tests and test devices. Methods: The authors developed a symbolic information extraction (SIE system to extract device and test specific information about four types of laboratory test entities: Specimens, analytes, units of measures and detection limits. They compared the performance of SIE and three prominent machine learning based NLP systems, LingPipe, GATE and BANNER, each implementing a distinct supervised machine learning method, hidden Markov models, support vector machines and conditional random fields, respectively. Results: Machine learning systems recognized laboratory test entities with moderately high recall, but low precision rates. Their recall rates were relatively higher when the number of distinct entity values (e.g., the spectrum of specimens was very limited or when lexical morphology of the entity was distinctive (as in units of measures, yet SIE outperformed them with statistically significant margins on extracting specimen, analyte and detection limit information in both precision and F-measure. Its high recall performance was statistically significant on analyte information extraction. Conclusions: Despite its shortcomings against machine learning methods, a well-tailored symbolic system may better discern relevancy among a pile of information of the same type and may outperform a machine learning system by tapping into lexically non-local contextual information such as the document structure.

  5. Performance testing of UK personal dosimetry laboratories

    CERN Document Server

    Marshall, T O

    1985-01-01

    The proposed Ionising Radiations Regulations will require all UK personal dosimetry laboratories that monitor classified personnel to be approved for personal dosimetry by the Health and Safety Executive. It is suggested that these approvals should be based on general and supplementary criteria published by the British Calibration Service (BCS) for laboratory approval for the provision of personal dosimetry services. These criteria specify certain qualitative requirements and also indicate the need for regular tests of performance to be carried out to ensure constancy of dosimetric standards. This report concerns the latter. The status of the BCS criteria is discussed and the need for additional documents to cover new techniques and some modifications to existing documents is indicated. A means is described by which the technical performance of laboratories, concerned with personal monitoring for external radiations, can be assessed, both initially and ongoing. The costs to establish the scheme and operate it...

  6. Laboratory testing in disseminated intravascular coagulation.

    Science.gov (United States)

    Favaloro, Emmanuel J

    2010-06-01

    The diagnosis of disseminated intravascular coagulation (DIC) relies on clinical signs and symptoms, identification of the underlying disease, the results of laboratory testing, and differentiation from other pathologies. The clinical features mainly depend on the underlying cause of the DIC. The laboratory diagnosis of DIC uses a combination of tests because no single test result alone can firmly establish or rule out the diagnosis. Global tests of hemostasis may initially provide evidence of coagulation activation and later in the process provide evidence of consumption of coagulation factors, but their individual diagnostic efficiency is limited. Fibrinolytic markers, in particular D-dimer, are reflective of activation of both coagulation and fibrinolysis, so that a normal finding can be useful for ruling-out DIC. Decreased levels of the natural anticoagulants (in particular, antithrombin and protein C) are frequently observed in patients with DIC, but their measurement is not normally incorporated into standard diagnostic algorithms. New tests are being explored for utility in DIC, and some additional tests may be useful on a case-by-case basis, depending on the proposed cause of the DIC or their local availability. For example, clot waveform analysis is useful but currently limited to a single instrument. Also, procalcitonin is an inflammatory biomarker that may be useful within the context of septic DIC, and activated factor X clotting time is an emerging test of procoagulant phospholipids that also seems to hold promise in DIC.

  7. Mars Science Laboratory Rover System Thermal Test

    Science.gov (United States)

    Novak, Keith S.; Kempenaar, Joshua E.; Liu, Yuanming; Bhandari, Pradeep; Dudik, Brenda A.

    2012-01-01

    On November 26, 2011, NASA launched a large (900 kg) rover as part of the Mars Science Laboratory (MSL) mission to Mars. The MSL rover is scheduled to land on Mars on August 5, 2012. Prior to launch, the Rover was successfully operated in simulated mission extreme environments during a 16-day long Rover System Thermal Test (STT). This paper describes the MSL Rover STT, test planning, test execution, test results, thermal model correlation and flight predictions. The rover was tested in the JPL 25-Foot Diameter Space Simulator Facility at the Jet Propulsion Laboratory (JPL). The Rover operated in simulated Cruise (vacuum) and Mars Surface environments (8 Torr nitrogen gas) with mission extreme hot and cold boundary conditions. A Xenon lamp solar simulator was used to impose simulated solar loads on the rover during a bounding hot case and during a simulated Mars diurnal test case. All thermal hardware was exercised and performed nominally. The Rover Heat Rejection System, a liquid-phase fluid loop used to transport heat in and out of the electronics boxes inside the rover chassis, performed better than predicted. Steady state and transient data were collected to allow correlation of analytical thermal models. These thermal models were subsequently used to predict rover thermal performance for the MSL Gale Crater landing site. Models predict that critical hardware temperatures will be maintained within allowable flight limits over the entire 669 Sol surface mission.

  8. 19 CFR 151.71 - Laboratory testing for clean yield.

    Science.gov (United States)

    2010-04-01

    ... 19 Customs Duties 2 2010-04-01 2010-04-01 false Laboratory testing for clean yield. 151.71 Section... Laboratory testing for clean yield. (a) Test and report by Customs laboratory. The clean yield of all general samples taken in accordance with § 151.70 shall be determined by test in a Customs laboratory, unless...

  9. DTU PMU Laboratory Development - Testing and Validation

    DEFF Research Database (Denmark)

    Garcia-Valle, Rodrigo; Yang, Guang-Ya; Martin, Kenneth E.;

    2010-01-01

    This is a report of the results of phasor measurement unit (PMU) laboratory development and testing done at the Centre for Electric Technology (CET), Technical University of Denmark (DTU). Analysis of the PMU performance first required the development of tools to convert the DTU PMU data into IEEE...... standard, and the validation is done for the DTU-PMU via a validated commercial PMU. The commercial PMU has been tested from the authors' previous efforts, where the response can be expected to follow known patterns and provide confirmation about the test system to confirm the design and settings....... In a nutshell, having 2 PMUs that observe same signals provides validation of the operation and flags questionable results with more certainty. Moreover, the performance and accuracy of the DTU-PMU is tested acquiring good and precise results, when compared with a commercial phasor measurement device, PMU-1....

  10. Stochastic optimization of laboratory test workflow at metallurgical testing centers

    Directory of Open Access Journals (Sweden)

    F. Tošenovský

    2016-10-01

    Full Text Available The objective of the paper is to present a way to shorten the time required to perform laboratory tests of materials in metallurgy. The paper finds a relation between the time to perform a test of materials and the number of technicians carrying out the test. The relation can be used to optimize the number of technicians. The approach is based on probability theory, as the amount of material to be tested is unknown in advance, and uses powerful modelling techniques involving the generalized estimating equations.

  11. TESTING OF THE RADBALL TECHNOLOGY AT SAVANNAH RIVER NATIONAL LABORATORY

    Energy Technology Data Exchange (ETDEWEB)

    Farfan, E.; Foley, T.

    2010-02-10

    The United Kingdom's National Nuclear Laboratory (NNL) has developed a remote, nonelectrical, radiation-mapping device known as RadBall (patent pending), which offers a means to locate and quantify radiation hazards and sources within contaminated areas of the nuclear industry. Positive results from initial deployment trials in nuclear waste reprocessing plants at Sellafield in the United Kingdom and the anticipated future potential use of RadBall throughout the U.S. Department of Energy Complex have led to the NNL partnering with the Savannah River National Laboratory (SRNL) to further test, underpin, and strengthen the technical performance of the technology. The study completed at SRNL addresses key aspects of the testing of the RadBall technology. The first set of tests was performed at Savannah River Nuclear Solutions Health Physics Instrument Calibration Laboratory (HPICL) using various gamma-ray sources and an x-ray machine with known radiological characteristics. The objective of these preliminary tests was to identify the optimal dose and collimator thickness. The second set of tests involved a highly contaminated hot cell. The objective of this testing was to characterize a hot cell with unknown radiation sources. The RadBall calibration experiments and hot cell deployment were successful in that for each trial radiation tracks were visible. The deployment of RadBall can be accomplished in different ways depending on the size and characteristics of the contaminated area (e.g., a hot cell that already has a crane/manipulator available or highly contaminated room that requires the use of a remote control device with sensor and video equipment to position RadBall). This report also presents SRNL-designed RadBall accessories for future RadBall deployment (a harness, PODS, and robot).

  12. Ensaios preliminares em laboratório para verificar a ação moluscicida de algumas espécies da flora brasileira Preliminary laboratory tests of the molluscicide activity of some species of Brazilian flora

    Directory of Open Access Journals (Sweden)

    Nelymar Martineli Mendes

    1984-10-01

    Full Text Available Estudou-se em laboratório a atividade moluscicida de 68 extratos de 23 plantas brasileiras. As soluções em água desclorada dos extratos hexânicos e etanólico, nas concentrações de 1, 10 e 100 ppm, foram testadas sobre caramujos adultos e desovas de Biomphalaria glabrata, criados em laboratório. As plantas que demonstraram ação moluscicida na concentração de 100 ppm foram: Arthemisia verlotorum Lamotte, Caesalpinia peltophoroides Benth, Cassia rugosa G.Don., Eclipta alba Hassk, Euphorbia pulcherrima Willd, Euphorbia splendens Bojer, Joannesia princeps Vell, Leonorus sibiricus L.,Macrosiphonia guaranitica Muell,Nerium oleander L., Palicourea nicotianaefolia Cham, e Schlech., Panicum maximum M., Rumex crispus L., Ruta graveolens L., e Stryphnodendron barbatiman M.The molluscicide activity of sixty-eight extracts from twenty-three Brazilian plants was studied in the laboratory. The solutions, in dechlorinated water, of hexanic and ethylic extracts at 1, 10 and 100 ppm concentrations, were tested on adult snails and egg masses of Biomphalaria glabrata, reared in the laboratory. The plants with molluscicide activity on adult snails and/or egg masses at 100 ppm concentration were: Arthemisia verlotorum Lamotte, Caesalpinia peltophoroides Benth, Cassia rugosa G. Don, Eclipta alba Hassk, Euphorbia pulcherrima Willd, Euphorbia splendens Bojer, Joannesia princeps Vell, Leonorus sibiricus L., Macrosiphonia guaranitica Muell, Nerium oleander L., Palicourea nicotianaefolia Cham. and Schlech., Panicum maximum M., Rumex crispus L., Ruta graveolens L. and Stryphnodendron barbatiman M.

  13. Laboratory tests of sludge-control additives

    Energy Technology Data Exchange (ETDEWEB)

    Tatnall, R.E. [MIC Associates, Inc., Chadds Ford, PA (United States)

    1996-07-01

    Laboratory {open_quotes}jar{close_quotes} tests compared eleven different fuel oil and diesel fuel sludge-control additives. Factors studied included (1) ability to disperse and prevent buildup of sludge deposits on surfaces, (2) ability to protect steel from corrosion, (3) ability to inhibit growth and proliferation of bacteria, and (4) ability to disperse water. Results varied greatly, and it was found that many commercial products do not do what they claim. It is concluded that fuel retailers should not believe manufacturers` claims for their additive products, but rather should test such products themselves to be sure that the benefits of treatment are real. A simplified form of the procedure used here is proposed as one way for dealers to do such testing.

  14. Laboratory rock mechanics testing manual. Public draft

    Energy Technology Data Exchange (ETDEWEB)

    Shuri, F S; Cooper, J D; Hamill, M L

    1981-10-01

    Standardized laboratory rock mechanics testing procedures have been prepared for use in the National Terminal Waste Storage Program. The procedures emphasize equipment performance specifications, documentation and reporting, and Quality Assurance acceptance criteria. Sufficient theoretical background is included to allow the user to perform the necessary data reduction. These procedures incorporate existing standards when possible, otherwise they represent the current state-of-the-art. Maximum flexibility in equipment design has been incorporated to allow use of this manual by existing groups and to encourage future improvements.

  15. Test plan for ISV laboratory-pyrolysis testing

    Energy Technology Data Exchange (ETDEWEB)

    McAtee, R.E.

    1991-09-01

    The objective of the laboratory-pyrolysis studies is to obtain information on the high temperature (< 1200{degree}C) degradation and alteration of organic chemicals and materials similar to those found in the Radioactive Waste Management Complex, Pit 9. This test plan describes experimental procedures, sampling and analysis strategy, sampling procedures, sample control, and document management. It addresses safety issues in the experimental apparatus and procedures, personal training, and hazardous waste disposal. Finally, it describes the data quality objectives using the EPA tiered approach to treatability studies to define where research/scoping tests fit into these studies and the EPA analytical levels required for the tests.

  16. Remotely accessible laboratory for MEMS testing

    Science.gov (United States)

    Sivakumar, Ganapathy; Mulsow, Matthew; Melinger, Aaron; Lacouture, Shelby; Dallas, Tim E.

    2010-02-01

    We report on the construction of a remotely accessible and interactive laboratory for testing microdevices (aka: MicroElectroMechancial Systems - MEMS). Enabling expanded utilization of microdevices for research, commercial, and educational purposes is very important for driving the creation of future MEMS devices and applications. Unfortunately, the relatively high costs associated with MEMS devices and testing infrastructure makes widespread access to the world of MEMS difficult. The creation of a virtual lab to control and actuate MEMS devices over the internet helps spread knowledge to a larger audience. A host laboratory has been established that contains a digital microscope, microdevices, controllers, and computers that can be logged into through the internet. The overall layout of the tele-operated MEMS laboratory system can be divided into two major parts: the server side and the client side. The server-side is present at Texas Tech University, and hosts a server machine that runs the Linux operating system and is used for interfacing the MEMS lab with the outside world via internet. The controls from the clients are transferred to the lab side through the server interface. The server interacts with the electronics required to drive the MEMS devices using a range of National Instruments hardware and LabView Virtual Instruments. An optical microscope (100 ×) with a CCD video camera is used to capture images of the operating MEMS. The server broadcasts the live video stream over the internet to the clients through the website. When the button is pressed on the website, the MEMS device responds and the video stream shows the movement in close to real time.

  17. Mars Science Laboratory Flight Software Internal Testing

    Science.gov (United States)

    Jones, Justin D.; Lam, Danny

    2011-01-01

    The Mars Science Laboratory (MSL) team is sending the rover, Curiosity, to Mars, and therefore is physically and technically complex. During my stay, I have assisted the MSL Flight Software (FSW) team in implementing functional test scripts to ensure that the FSW performs to the best of its abilities. There are a large number of FSW requirements that have been written up for implementation; however I have only been assigned a few sections of these requirements. There are many stages within testing; one of the early stages is FSW Internal Testing (FIT). The FIT team can accomplish this with simulation software and the MSL Test Automation Kit (MTAK). MTAK has the ability to integrate with the Software Simulation Equipment (SSE) and the Mission Processing and Control System (MPCS) software which makes it a powerful tool within the MSL FSW development process. The MSL team must ensure that the rover accomplishes all stages of the mission successfully. Due to the natural complexity of this project there is a strong emphasis on testing, as failure is not an option. The entire mission could be jeopardized if something is overlooked.

  18. Laboratory test surveillance following acute kidney injury.

    Directory of Open Access Journals (Sweden)

    Michael E Matheny

    Full Text Available BACKGROUND: Patients with hospitalized acute kidney injury (AKI are at increased risk for accelerated loss of kidney function, morbidity, and mortality. We sought to inform efforts at improving post-AKI outcomes by describing the receipt of renal-specific laboratory test surveillance among a large high-risk cohort. METHODS: We acquired clinical data from the Electronic health record (EHR of 5 Veterans Affairs (VA hospitals to identify patients hospitalized with AKI from January 1st, 2002 to December 31st, 2009, and followed these patients for 1 year or until death, enrollment in palliative care, or improvement in renal function to estimated GFR (eGFR ≥ 60 L/min/1.73 m(2. Using demographic data, administrative codes, and laboratory test data, we evaluated the receipt and timing of outpatient testing for serum concentrations of creatinine and any as well as quantitative proteinuria recommended for CKD risk stratification. Additionally, we reported the rate of phosphorus and parathyroid hormone (PTH monitoring recommended for chronic kidney disease (CKD patients. RESULTS: A total of 10,955 patients admitted with AKI were discharged with an eGFR<60 mL/min/1.73 m2. During outpatient follow-up at 90 and 365 days, respectively, creatinine was measured on 69% and 85% of patients, quantitative proteinuria was measured on 6% and 12% of patients, PTH or phosphorus was measured on 10% and 15% of patients. CONCLUSIONS: Measurement of creatinine was common among all patients following AKI. However, patients with AKI were infrequently monitored with assessments of quantitative proteinuria or mineral metabolism disorder, even for patients with baseline kidney disease.

  19. Laboratory test surveillance following acute kidney injury.

    Science.gov (United States)

    Matheny, Michael E; Peterson, Josh F; Eden, Svetlana K; Hung, Adriana M; Speroff, Theodore; Abdel-Kader, Khaled; Parr, Sharidan K; Ikizler, T Alp; Siew, Edward D

    2014-01-01

    Patients with hospitalized acute kidney injury (AKI) are at increased risk for accelerated loss of kidney function, morbidity, and mortality. We sought to inform efforts at improving post-AKI outcomes by describing the receipt of renal-specific laboratory test surveillance among a large high-risk cohort. We acquired clinical data from the Electronic health record (EHR) of 5 Veterans Affairs (VA) hospitals to identify patients hospitalized with AKI from January 1st, 2002 to December 31st, 2009, and followed these patients for 1 year or until death, enrollment in palliative care, or improvement in renal function to estimated GFR (eGFR) ≥ 60 L/min/1.73 m(2). Using demographic data, administrative codes, and laboratory test data, we evaluated the receipt and timing of outpatient testing for serum concentrations of creatinine and any as well as quantitative proteinuria recommended for CKD risk stratification. Additionally, we reported the rate of phosphorus and parathyroid hormone (PTH) monitoring recommended for chronic kidney disease (CKD) patients. A total of 10,955 patients admitted with AKI were discharged with an eGFR<60 mL/min/1.73 m2. During outpatient follow-up at 90 and 365 days, respectively, creatinine was measured on 69% and 85% of patients, quantitative proteinuria was measured on 6% and 12% of patients, PTH or phosphorus was measured on 10% and 15% of patients. Measurement of creatinine was common among all patients following AKI. However, patients with AKI were infrequently monitored with assessments of quantitative proteinuria or mineral metabolism disorder, even for patients with baseline kidney disease.

  20. 49 CFR 199.107 - Drug testing laboratory.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 3 2010-10-01 2010-10-01 false Drug testing laboratory. 199.107 Section 199.107... § 199.107 Drug testing laboratory. (a) Each operator shall use for the drug testing required by this part only drug testing laboratories certified by the Department of Health and Human Services under...

  1. 42 CFR 493.1403 - Condition: Laboratories performing moderate complexity testing; laboratory director.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 5 2010-10-01 2010-10-01 false Condition: Laboratories performing moderate complexity testing; laboratory director. 493.1403 Section 493.1403 Public Health CENTERS FOR MEDICARE... LABORATORY REQUIREMENTS Personnel for Nonwaived Testing Laboratories Performing Moderate Complexity...

  2. How to test NISP instrument for EUCLID mission in laboratory

    Science.gov (United States)

    Costille, A.; Carle, Michael; Fabron, Christophe; Prieto, Eric; Beaumont, Florent; Jessen, Niels-Christian; Jakobsen, Peter; Sørensen, Anton N.; Andersen, Michael I.; Grupp, Frank; Maciaszek, Thierry; Ealet, Anne; Gillard, William; Clemens, Jean-Claude

    2016-07-01

    The ESA mission Euclid is designed to explore the dark side of the Universe. The NISP (Near Infrared Spectro- Photometer) is one of its two instruments operating in the near-IR spectral region (0.9-2μm), that will be fully integrated and tested at Laboratory d'Astrophysique de Marseille (LAM) under vacuum and thermal conditions. The test campaign will regroup functional tests, performance tests, calibration procedure validation and observations scenario test. One of the main objectives of the test campaign will be the measurement of the focus position of NISP with respect to the EUCLID object plane. To achieve these tests campaign, a global Ground Support Equipment (GSE) called the Verification Ground System (VGS) has to be developed. It will be a complex set of GSE integrated in ERIOS chamber made of: a telescope simulator to simulate the EUCLID telescope and to inject light into NISP, a thermal environment to be used for NISP thermal balance and verification, a sets of mechanical interfaces to align all the parts into ERIOS chamber, the NISP Electrical GSE (EGSE) to control the instrument during the test and a metrology system to measure the positions of the components during the test. We will present the preliminary design and concepts of the VGS and we will show the main difficulties we have to deal with: design of thermal environment at 80K with 4mK stability, the development of a metrology system in vacuum, knowledge of the focus position within 150μm in cold, etc. The main objectives of the NISP test will be explained and how the VGS responds to the test requirement.

  3. Optimizing tuberculosis testing for basic laboratories.

    Science.gov (United States)

    Ramos, Eric; Schumacher, Samuel G; Siedner, Mark; Herrera, Beatriz; Quino, Willi; Alvarado, Jessica; Montoya, Rosario; Grandjean, Louis; Martin, Laura; Sherman, Jonathan M; Gilman, Robert H; Evans, Carlton A

    2010-10-01

    Optimal tuberculosis testing usually involves sputum centrifugation followed by broth culture. However, centrifuges are biohazardous and scarce in the resource-limited settings where most tuberculosis occurs. To optimize tuberculosis testing for these settings, centrifugation of 111 decontaminated sputum samples was compared with syringe-aspiration through polycarbonate membrane-filters that were then cultured in broth. To reduce the workload of repeated microscopic screening of broth cultures for tuberculosis growth, the colorimetric redox indicator 2,3-diphenyl-5-(2-thienyl) tetrazolium chloride was added to the broth, which enabled naked-eye detection of culture positivity. This combination of filtration and colorimetric growth-detection gave similar results to sputum centrifugation followed by culture microscopy regarding mean colony counts (43 versus 48; P = 0.6), contamination rates (0.9% versus 1.8%; P = 0.3), and sensitivity (94% versus 95%; P = 0.7), suggesting equivalency of the two methods. By obviating centrifugation and repeated microscopic screening of cultures, this approach may constitute a more appropriate technology for rapid and sensitive tuberculosis diagnosis in basic laboratories.

  4. 9 CFR 590.580 - Laboratory tests and analyses.

    Science.gov (United States)

    2010-01-01

    ... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false Laboratory tests and analyses. 590.580... EGG PRODUCTS INSPECTION INSPECTION OF EGGS AND EGG PRODUCTS (EGG PRODUCTS INSPECTION ACT) Laboratory § 590.580 Laboratory tests and analyses. The official plant, at their expense, shall make tests...

  5. Quality of HIV laboratory testing in Tanzania: a situation analysis.

    Science.gov (United States)

    Mfinanga, G S; Mutayoba, B; Mbogo, G; Kahwa, A; Kimaro, G; Mhame, P P; Mwangi, C; Malecela, M N; Kitua, A Y

    2007-01-01

    Tanzania is scaling up prevention, treatment, care and support of individuals affected with HIV. There is therefore a need for high quality and reliable HIV infection testing and AIDS staging. The objective of this study was to assess laboratories capacities of services in terms of HIV testing and quality control. A baseline survey was conducted from December 2004 to February 2005 in 12 laboratories which were conveniently selected to represent all the zones of Tanzania. The questionnaires comprised of questions on laboratory particulars, internal and external quality control for HIV testing and quality control of reagents. Source and level of customer satisfaction of HIV test kits supply was established. Of 12 laboratories, nine used rapid tests for screening and two used rapid tests for diagnosis. In the 12 laboratories, four used double ELISA and five used single ELISA and three did not use ELISA. Confirmatory tests observed were Western Blot in three laboratories, DNA PCR in two laboratories, CD4 counting in seven laboratories, and viral load in two laboratories. Although all laboratories conducted quality control (QC) of the HIV kits, only two laboratories had Standard Operating Procedures (SOPs). Internal and external quality control (EQC) was done at varied proportions with the highest frequency of 55.6% (5/9) for internal quality control (IQC) for rapid tests and EQC for ELISA, and the lowest frequency of 14.3% (1/ 7) for IQC for CD4 counting. None of the nine laboratories which conducted QC for reagents used for rapid tests and none of the five which performed IQC and EQC had SOPs. HIV kits were mainly procured by the Medical Store Department and most of laboratories were not satisfied with the delay in procurement procedures. Most of the laboratories used rapid tests only, while some used both rapid tests and ELISA method for HIV testing. In conclusion, the survey revealed inadequacy in Good Laboratory Practice and poor laboratory quality control process

  6. USING LABORATORY TESTS TO PREDICT OXIDATION IN TODAY'S ENGINES

    Institute of Scientific and Technical Information of China (English)

    2004-01-01

    Laboratory bench tests are used to predict lubricant performance in modern engines. The evolution of ASTM (American Society of Testing and Materials) engine Sequence tests and associated laboratory bench tests is reviewed. Several oxidation screening tests are described. Correlation of oxidation screening tests with ASTM Sequence Ⅲ high temperature oxidation engine test is addressed, using both European and ASTM reference oils. Modification of the oxidation screening test methods is attempted in order to improve the correlation as the Sequence Ⅲ test method evolves.

  7. Testing the Preliminary X-33 Navigation System

    Science.gov (United States)

    Lomas, James J.; Mitchell, Daniel W.; Freestone, Todd M.; Lee, Charles; Lessman, Craig; Foster, Lee D. (Technical Monitor)

    2001-01-01

    The X-33 Reusable Launch Vehicle (RLV) must meet the demanding requirements of landing autonomously on a narrow landing strip following a flight that reaches an altitude of up to 200,000 feet and a speed in excess of Mach 9 with significant in-flight energy bleed-off maneuvers. To execute this flight regimen a highly reliable avionics system has been designed that includes three LN-100G Inertial Navigation System/Global Positioning System (INS/GPS) units as the primary navigation system for the X-33. NASA's Marshall Space Flight Center (MSFC) tested an INS/GPS system in real-time simulations to determine the ability of this navigation suite to meet the in flight and autonomous landing requirements of the X-33 RLV. A total of sixty-one open loop tests were performed to characterize the navigation accuracy of the LN-100G. Twenty-seven closed-loop tests were also performed to evaluate the performance of the X-33 Guidance, Navigation and Control (GN&C) algorithms with the real navigation hardware. These closed-loop tests were also designed to expose any integration or operational issues with the real-time X-33 vehicle simulation. Dynamic road tests of the INS/GPS were conducted by Litton to assess the performance of differential and nondifferential INS/GPS hybrid navigation solutions. The results of the simulations and road testing demonstrate that this novel solution is capable of meeting the demanding requirements of take-off, in-flight navigation, and autonomous landing of the X-33 RLV. This paper describes the test environment developed to stimulate the LN-100G and discusses the results of this test effort. This paper also presents recommendations for a navigation system suitable to an operational RLV system.

  8. EM techniques for archaeological laboratory experiments: preliminary results

    Science.gov (United States)

    Capozzoli, Luigi; De Martino, Gregory; Giampaolo, Valeria; Raffaele, Luongo; Perciante, Felice; Rizzo, Enzo

    2015-04-01

    The electromagnetic techniques (EM) are based on the investigation of subsoil geophysical parameters and in the archaeological framework they involve in studying contrasts between the buried cultural structures and the surrounding materials. Unfortunately, the geophysical contrast between archaeological features and surrounding soils sometimes are difficult to define due to problems of sensitivity and resolution both related on the characteristic of the subsoil and the geophysical methods. For this reason an experimental activity has been performed in the Hydrogeosite laboratory addressed on the assessment of the capability of geophysical techniques to detect archeological remains placed in the humid/saturated subsoil. At Hydrogeosite Laboratory of CNR-IMAA, a large scale sand-box is located, consisting on a pool shape structures of 230m3 where archaeological remains have been installed . The remains are relative to a living environment and burial of Roman times (walls, tombs, roads, harbour, etc.) covered by sediments. In order to simulate lacustrine and wetland condition and to simulate extreme events (for example underwater landslide, fast natural erosion coast, etc.) the phreatic level was varied and various acquisitions for the different scenarios were performed. In order to analyze the EM behavior of the buried small archaeological framework, ground penetrating radar (GPR) and electrical resistivity tomographies were performed. With GPR, analysis in time domain and frequency domain were performed and coupled to information obtained through resistivity analysis with the support of numerical simulations used to compare the real data with those modeled. A dense grid was adopted for 400 and 900 MHz e-m acquisitions in both the directions, the maximum depth of investigation was limited and less than 3 meters. The same approach was used for ERT acquisition where different array are employed, in particular 3D configuration was used to carry out a 3D resistivity

  9. Laboratory tests used in US public health laboratories for sexually transmitted diseases, 2000.

    Science.gov (United States)

    Dicker, Linda Webster; Mosure, Debra J; Steece, Richard; Stone, Katherine M

    2004-05-01

    Public health laboratories are a critical component of sexually transmitted disease (STD) control in the United States. The goal of this study was to describe the types and volume of STD tests performed in U.S. public health laboratories in 2000. A survey was mailed to 123 members of the Association of Public Health Laboratories. Eighty-one percent of 100 laboratories responded. Overall, 3294739 chlamydia tests and 3088142 gonorrhea tests were done; 62.4% of chlamydia tests and 63.6% of gonorrhea tests were DNA probes. Fifty-six percent of laboratories performed rapid plasma reagin (RPR) tests and 55% performed Venereal Disease Research Laboratory (VDRL) tests; the number of RPR tests performed was twice that of VDRL tests. Few laboratories used new technologies for bacterial vaginosis and trichomoniasis. Eighteen percent of laboratories performed herpes simplex virus serology; however, most used inaccurate tests. No laboratories performed human papillomavirus tests. This survey documents for the first time STD tests performed in U.S. public health laboratories.

  10. 16 CFR 305.22 - Required testing by designated laboratory.

    Science.gov (United States)

    2010-01-01

    ... 16 Commercial Practices 1 2010-01-01 2010-01-01 false Required testing by designated laboratory...) Additional Requirements § 305.22 Required testing by designated laboratory. Upon notification by the... manufacturer's expense, no more than two of each model of each product to a laboratory, which will...

  11. Comparison of Rapid Malaria Test and Laboratory Microscopy ...

    African Journals Online (AJOL)

    Michael Horsfall

    Comparison of Rapid Malaria Test and Laboratory Microscopy Investigation for ... of the low parasite density cases could escape detection, therefore, it cannot replace laboratory ..... WHO (1990): World Report of the tropical disease,.

  12. Preliminary Test for Nonlinear Input Output Relations in SISO Systems

    DEFF Research Database (Denmark)

    Knudsen, Torben

    2000-01-01

    This paper discusses and develops preliminary statistical tests for detecting nonlinearities in the deterministic part of SISO systems with noise. The most referenced method is unreliable for common noise processes as e.g.\\ colored. Therefore two new methods based on superposition and sinus input...

  13. New technologies to improve laboratory testing

    Science.gov (United States)

    Burtis, C. A.

    Several core technologies that are having, or will have, an impact on the clinical laboratory are discussed. These include instrument-related technologies such as computer technology, chemometrics, robotics, sensors, and biological technologies such as cell fusion and recombinant DNA.

  14. The picture test of separation and individuation - preliminary research

    OpenAIRE

    Gregor Žvelc; Maša Žvelc

    2000-01-01

    Authors introduce a new instrument, which they developed for measuring separation and individuation process and attachment in adolescence and adulthood. The Picture Test of Separation and Individuation (PTSI) is a semi–projective test. It consists of various pictures, which represent relationships with significant others. PTSI is divided into three subtests: Relationship with Mother, Relationship with Father and Attachment. In a preliminary research on a sample of college and university...

  15. Transportable Emissions Testing Laboratory for Alternative Vehicles Emissions Testing

    Energy Technology Data Exchange (ETDEWEB)

    Clark, Nigel

    2012-01-31

    The overall objective of this project was to perform research to quantify and improve the energy efficiency and the exhaust emissions reduction from advanced technology vehicles using clean, renewable and alternative fuels. Advanced vehicle and alternative fuel fleets were to be identified, and selected vehicles characterized for emissions and efficiency. Target vehicles were to include transit buses, school buses, vocational trucks, delivery trucks, and tractor-trailers. Gaseous species measured were to include carbon monoxide, carbon dioxide, oxides of nitrogen, hydrocarbons, and particulate matter. An objective was to characterize particulate matter more deeply than by mass. Accurate characterization of efficiency and emissions was to be accomplished using a state-of-the-art portable emissions measurement system and an accompanying chassis dynamometer available at West Virginia University. These two units, combined, are termed the Transportable Laboratory. An objective was to load the vehicles in a real-world fashion, using coast down data to establish rolling resistance and wind drag, and to apply the coast down data to the dynamometer control. Test schedules created from actual vehicle operation were to be employed, and a specific objective of the research was to assess the effect of choosing a test schedule which the subject vehicle either cannot follow or can substantially outperform. In addition the vehicle loading objective was to be met better with an improved flywheel system.

  16. 7 CFR 58.523 - Laboratory and quality control tests.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 3 2010-01-01 2010-01-01 false Laboratory and quality control tests. 58.523 Section... Service 1 Operations and Operating Procedures § 58.523 Laboratory and quality control tests. (a) Quality control tests shall be made on samples as often as necessary to determine the shelf-life and stability...

  17. Workgroup for Hydraulic laboratory Testing and Verification of Hydroacoustic Instrumentation

    Science.gov (United States)

    Fulford, Janice M.; Armstrong, Brandy N.; Thibodeaux, Kirk G.

    2015-01-01

    An international workgroup was recently formed for hydraulic laboratory testing and verification of hydroacoustic instrumentation used for water velocity measurements. The activities of the workgroup have included one face to face meeting, conference calls and an inter-laboratory exchange of two acoustic meters among participating laboratories. Good agreement was found among four laboratories at higher tow speeds and poorer agreement at the lowest tow speed.

  18. Definition study for an extended manned test of a regenerative life support system, preliminary test plan

    Science.gov (United States)

    1971-01-01

    A preliminary plan and procedure are presented for conducting an extended manned test program for a regenerative life support system. Emphasis will be placed on elements associated with long-term system operation and long-term uninterrupted crew confinement.

  19. Laboratory Tests of Small SDHW Systems

    DEFF Research Database (Denmark)

    Furbo, Simon; Shah, Louise Jivan

    1997-01-01

    A test facility for Small SDHW systems was built in 1992. In the test facility up to 10 SDHW systems can be tested side-by-side under the same realistic conditions. Since 1992 16 different systems have been tested in the facility. Both test systems and marketed systems from Danish as well...... as foreign manufacturers have been tested.The thermal performances of the systems have been measured for periods with a duration of about 1 year. In this way direct comparisons of the thermal performances of the different systems are possible.Further, measured and calculated thermal performances for all...... models the yearly thermal performances of the tested systems have been determined with the Danish Test Reference Year as the weather data. Based on calculations with the models improvements of the design of the different systems have been recommended.Experience from the operation of the different systems...

  20. Laboratory Test Requirements for Marine Shock Isolation Seats

    Science.gov (United States)

    2015-05-01

    Program Executive Office Ships, Support Ships, Boats, and Craft Program Office (PMS 325G). ACKNOWLEDGEMENTS The authors would like to thank Mr...laboratory before installation in a high-speed planing craft . It includes testing procedures, instrumentation system guidance, data processing requirements...or techniques are developed. . 15. SUBJECT TERMS Shock isolation seat laboratory test high-speed craft 16. SECURITY

  1. 7 CFR 58.442 - Laboratory and quality control tests.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 3 2010-01-01 2010-01-01 false Laboratory and quality control tests. 58.442 Section... Service 1 Operations and Operating Procedures § 58.442 Laboratory and quality control tests. (a) Chemical... Methods or by other methods giving equivalent results. (b) Weight or volume control....

  2. [Basic standards for Colombian paternity testing laboratories, 2005].

    Science.gov (United States)

    Giraldo, Alejandro; Bermúdez, Antonio; Jiménez, Magda; Lizarazo, Rocio

    2006-01-01

    The Commission for Accreditation and Surveillance of Laboratories Practicing DNA Paternity Tests (created by the Colombian Law 721/2001) set up sub-commission to review the current basic Colombian standards required for paternity testing laboratories and make specific recommendations re the pertinent technical aspects in Colombia, taking ISO 17025 as current reference. This document contains such recommendations for Colombia.

  3. 19 CFR 151.54 - Testing by Customs laboratory.

    Science.gov (United States)

    2010-04-01

    ... 19 Customs Duties 2 2010-04-01 2010-04-01 false Testing by Customs laboratory. 151.54 Section 151.54 Customs Duties U.S. CUSTOMS AND BORDER PROTECTION, DEPARTMENT OF HOMELAND SECURITY; DEPARTMENT OF... Other Metal-Bearing Materials § 151.54 Testing by Customs laboratory. Samples taken in accordance...

  4. Human Papillomavirus Laboratory Testing: the Changing Paradigm

    Science.gov (United States)

    2016-01-01

    SUMMARY High-risk human papillomaviruses (HPVs) cause essentially all cervical cancers, most anal and oropharyngeal cancers, and some vaginal, vulvar, and penile cancers. Improved understanding of the pathogenesis of infection and the availability of newer tests are changing the approach to screening and diagnosis. Molecular tests to detect DNA from the most common high-risk HPVs are FDA approved for use in conjunction with cytology in cervical cancer screening programs. More-specific tests that detect RNA from high-risk HPV types are now also available. The use of molecular tests as the primary screening tests is being adopted in some areas. Genotyping to identify HPV16 and -18 has a recommended role in triaging patients for colposcopy who are high-risk HPV positive but have normal cytology. There are currently no recommended screening methods for anal, vulvar, vaginal, penile, or oropharyngeal HPV infections. HPV testing has limited utility in patients at high risk for anal cancer, but p16 immunohistochemistry is recommended to clarify lesions in tissue biopsy specimens that show moderate dysplasia or precancer mimics. HPV testing is recommended for oropharyngeal squamous cell tumors as a prognostic indicator. Ongoing research will help to improve the content of future guidelines for screening and diagnostic testing. PMID:26912568

  5. Recent laboratory tests with elastomeric revetments

    NARCIS (Netherlands)

    Verhagen, H.J.

    2009-01-01

    A new construction method of Polyurethane (PUR)-bonded revetments has been tested successfully on various locations in Germany, in the Netherlands, in France, and in the UK. See also the presentation of Bijlsma on this ICE breakwater conference. This year a series of large scale test in the GWK-faci

  6. Advanced Laboratory Setup for Testing Offshore Foundations

    DEFF Research Database (Denmark)

    Nielsen, Søren Dam; Ibsen, Lars Bo; Nielsen, Benjaminn Nordahl

    2016-01-01

    This paper describes a test setup for testing small-scale offshore foundations under realistic conditions of high pore-water pressure and high impact loads. The actuator, used for loading has enough capacity to apply sufficient force and displacement to achieve both drained and undrained failure ...

  7. Preliminary study: Formaldehyde exposure in laboratories of Sharjah university in UAE

    Directory of Open Access Journals (Sweden)

    Hafiz Omer Ahmed

    2011-01-01

    Full Text Available Objectives : Laboratory technicians, students, and instructors are at high risk, because they deal with chemicals including formaldehyde. Thus, this preliminary study was conducted to measure the concentration of formaldehyde in the laboratories of the University of Sharjah in UAE. Materials and Methods: Thirty-two air samples were collected and analyzed for formaldehyde using National Institute for Occupational Safety and Health (NIOSH method 3500. In this method, formaldehyde reacts with chromotropic acid in the presence of sulfuric acid to form a colored solution. The absorbance of the colored solution is read in spectrophotometer at wavelength 580 nm and is proportional to the quantity of the formaldehyde in the solution. Results: For the anatomy laboratory and in the presence of the covered cadaver, the mean concentration of formaldehyde was found to be 0.100 ppm with a range of 0.095-0.105 ppm. Whereas for the other laboratories, the highest mean concentration of formaldehyde was 0.024 ppm in the general microbiology laboratory and the lowest mean concentration of formaldehyde was 0.001 ppm in the environmental health laboratory. The 8-hour (time-weighted average concentration of formaldehyde was found to be ranging between 0.0003 ppm in environmental health laboratory and 0.026 ppm in the anatomy laboratory. Conclusions: The highest level of concentration of formaldehyde in the presence of the covered cadaver in anatomy laboratory exceeded the recommended ceiling standard established by USA-NIOSH which is 0.1 ppm, but below the ceiling standard established by American Conference of Governmental Industrial Hygienists which is 0.3 ppm. Thus, it is recommended that formaldehyde levels should be measured periodically specially during the dissection in the anatomy laboratory, and local exhaust ventilation system should be installed and personal protective equipment such as safety glass and gloves should be available and be used to prevent

  8. Inter-laboratory proficiency tests to detect viral fish diseases

    DEFF Research Database (Denmark)

    Kahns, Søren; Nicolajsen, Nicole; Skall, Helle Frank

    of the rhabdoviruses identified in order to analyse the inter-laboratory quality of sequencing results. Such results are very important for assessing how sequence data can be used in e.g. molecular tracing. Here we present results and experiences obtained from these additional studies.......An inter-laboratory proficiency test has ben provided by the European Community Laboratory (CRL) for Fish Diseases every year since 1996. The test is provided to all European National Reference Laboratories (NRLs) that are obliged to participate and to a limited number of non-European NRLs, making...... the total number of participating laboratories 35. The test is primarily designed to assess the ability of participating laboratories to identify and quantify the notifiable non-exotic fish pathogenic viruses: Viral haemorrhagic septicaemia virus (VHSV) and infectious haematopietic necrosis virus (IHNV...

  9. Laboratory effectiveness testing of oil spill dispersants

    Energy Technology Data Exchange (ETDEWEB)

    Fingas, M.F.; Kyle, D.A.; Wang, Z.; Handfield, D.; Ianuzzi, D.; Ackerman, F. [Environment Canada, Ottawa, Ontario (Canada)

    1995-06-01

    Dispersant effectiveness tests are reviewed. Studies have been conducted of the variances among several standard regulatory tests. Three main causes of differences have been identified, oil-to-water ratio, settling time and energy. Energy can be partially compensated for in high energy tests by correcting for natural dispersion. With this correction and with high oil-to-water ratios and a settling time of at least 10 minutes, five apparatuses yield very similar results for a variety of oils and dispersants. Recent studies into the energy variation of dispersant tests show that the energy level varies in many apparatuses. The repeatability of energy levels in apparatus is largely responsible for the variation in dispersant effectiveness values in certain apparatus. Studies of analytical procedures show that traditional extraction and analysis methods cause a bias to results. Methods to overcome these difficulties are presented.

  10. Laboratory results of the AOF system testing

    Science.gov (United States)

    Kolb, Johann; Madec, Pierre-Yves; Arsenault, Robin; Oberti, Sylvain; Paufique, Jérôme; La Penna, Paolo; Ströbele, Stefan; Donaldson, Robert; Soenke, Christian; Suárez Valles, Marcos; Kiekebusch, Mario; Argomedo, Javier; Le Louarn, Miska; Vernet, Elise; Haguenauer, Pierre; Duhoux, Philippe; Aller-Carpentier, Emmanuel; Valenzuela, Jose Javier; Guerra, Juan Carlos

    2016-07-01

    For two years starting in February 2014, the AO modules GRAAL for HAWK-I and GALACSI for MUSE of the Adaptive Optics Facility project have undergone System Testing at ESO's Headquarters. They offer four different modes: NGS SCAO, LGS GLAO in the IR, LGS GLAO and LTAO in the visible. A detailed characterization of those modes was made possible by the existence of ASSIST, a test bench emulating an adaptive VLT including the Deformable Secondary Mirror, a star simulator and turbulence generator and a VLT focal plane re-imager. This phase aimed at validating all the possible components and loops of the AO modules before installation at the actual VLT that comprises the added complexity of real LGSs, a harsher non-reproducible environment and the adaptive telescope control. In this paper we present some of the major results obtained and challenges encountered during the phase of System Tests, like the preparation of the Acquisition sequence, the testing of the Jitter loop, the performance optimization in GLAO and the offload of low-order modes from the DSM to the telescope (restricted to the M2 hexapod). The System Tests concluded with the successful acceptance, shipping, installation and first commissioning of GRAAL in 2015 as well as the acceptance and shipping of GALACSI, ready for installation and commissioning early 2017.

  11. The picture test of separation and individuation - preliminary research

    Directory of Open Access Journals (Sweden)

    Gregor Žvelc

    2000-06-01

    Full Text Available Authors introduce a new instrument, which they developed for measuring separation and individuation process and attachment in adolescence and adulthood. The Picture Test of Separation and Individuation (PTSI is a semi–projective test. It consists of various pictures, which represent relationships with significant others. PTSI is divided into three subtests: Relationship with Mother, Relationship with Father and Attachment. In a preliminary research on a sample of college and university students authors studied basic properties of the test. The results of the research indicate that PTSI is consistent with theoretical background, has good sensitivity and is economical. The Picture Test of Separation and Individuation enables quick but complex insight into individual's relationships with significant others as well as into his/her stage of separation and individuation process. Considering satisfying results of pilot study, authors suggest further research for validation of the test.

  12. Influence of diet on the results of laboratory tests

    Directory of Open Access Journals (Sweden)

    Kinga Lis

    2013-12-01

    Full Text Available Blood and urine laboratory tests are necessary to diagnose the state of the patient. These tests are also helpful in the assessment of diet and nutritional status of the organism. It is recommended that both blood and urine for laboratory tests be collected in the morning, from fasting patients after an overnight rest. These conditions are defined as the standard conditions for collection of material for laboratory testing. Before testing, patients should follow their natural diet and avoid physical exertion, night work, long-distance travel, as well as consumption of alcohol and drugs. They should also reduce the consumption of synthetic vitamins and herbal remedies and other dietary supplements. Medications should be limited to those that are absolutely necessary. All of these factors can affect the results of laboratory tests.

  13. Laboratory tests of hydraulic fracturing and swell healing

    DEFF Research Database (Denmark)

    Thunbo, Christensen Claes; Foged, Christensen Helle; Foged, Niels

    1998-01-01

    New laboratory test set-ups and test procedures are described - for testing the formation of hydraulically induced fractures as well as the potential for subsequent fracture closurefrom the relase of a swelling potential. The main purpose with the tests is to provide information on fracturing...

  14. Laboratory-scale integrated ARP filter test

    Energy Technology Data Exchange (ETDEWEB)

    Poirier, M. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL); Burket, P. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL)

    2016-03-01

    The Savannah River Site (SRS) is currently treating radioactive liquid waste with the Actinide Removal Process (ARP) and the Modular Caustic Side Solvent Extraction Unit (MCU). Recently, the low filter flux through the ARP of approximately 5 gallons per minute has limited the rate at which radioactive liquid waste can be treated. Salt Batch 6 had a lower processing rate and required frequent filter cleaning. There is a desire to understand the causes of the low filter flux and to increase ARP/MCU throughput. This task attempted to simulate the entire ARP process, including multiple batches (5), washing, chemical cleaning, and blending the feed with heels and recycle streams. The objective of the tests was to determine whether one of these processes is causing excessive fouling of the crossflow or secondary filter. The authors conducted the tests with feed solutions containing 6.6 M sodium Salt Batch 6 simulant supernate with no MST.

  15. The Farley Instability: A Laboratory Test

    DEFF Research Database (Denmark)

    D'Angelo, N.; Pécseli, Hans; Petersen, P. I.

    1974-01-01

    An experiment is described that was performed in an alkali plasma (Cs) device in order to test the theory of the Farley instability. With υ E×B > Cs (the speed of sound) and νι ≳ ω cι (ν e ≪ ω ce ) wave excitation occurs, the waves traveling normal to the magnetic field B at the υ E×B speed....... The perturbations are strongly elongated along the B field lines, with λ∥ ≫ λ⊥. A comparison with theoretical predictions is given for the observed excitation conditions of the instability....

  16. Laboratory Facilities for Testing Thermal Engines

    Directory of Open Access Journals (Sweden)

    Ioan Ruja

    2010-10-01

    Full Text Available This work presents an electromechanical plant through with which is realised couples different resistant, MR (0 ÷ MRN, on the gearbox shaft of internal combustion engine. The purpose is to study the plant in phase and stationary behaviour of the main technical parameters that define the engine operation such as: torque, speed, temperature, pressure, vibration, burnt gas, noise, forces. You can take measurements to determine engine performance testing and research on improving engine thermal efficiency. With the proposed plant is built by measuring the characteristic internal combustion engines (tuning characteristic and functional characteristic and determine the technical performance of interest, optimal.

  17. Coal-water-slurry evaluation. Volume 2. Laboratory and combustion test results. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Daley, R.D.; Farthing, G.A.; Vecci, S.J.

    1984-02-01

    This is the second of three volumes describing a multi-phase coal-water slurry (CWS) test program. This volume presents the results of laboratory, atomization, and combustion tests which were performed on six slurries and their parent coals. The objectives of these tests was to establish laboratory test procedures for evaluating CWS fuels, to investigate relationships between laboratory properties and CWS combustion and handling characteristics and to develop preliminary guidelines for CWS specifications. These tests showed that the preparation processes and chemical additives used by the slurry manufacturers had a significant effect on viscosity and atomization properties. The most important factor for good combustion performance was droplet size, but droplet size did not correlate with viscosity measured at low shear rates in the laboratory tests. It was also found that some slurries had greater fouling potential than their parent coals due to the use of sodium-containing additives. Tests were also conducted to determine whether the slurries could be transported and stored without coal settling. These tests showed that little settling occurred during either transportation or storage for at least three weeks. 98 figures, 27 tables.

  18. 42 CFR 493.1441 - Condition: Laboratories performing high complexity testing; laboratory director.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 5 2010-10-01 2010-10-01 false Condition: Laboratories performing high complexity testing; laboratory director. 493.1441 Section 493.1441 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) STANDARDS AND CERTIFICATION...

  19. Characteristics, finite element analysis, test description, and preliminary test results of the STM4-120 kinematic Stirling engine

    Science.gov (United States)

    Linker, K. L.; Rawlinson, K. S.; Smith, G.

    1991-10-01

    The Department of Energy's Solar Thermal Program has, as one of its program elements, the development and evaluation of conversion device technologies applicable to dish-electric systems. The primary research and development combines a conversion device (heat engine), solar receiver, and generator mounted at the focus of a parabolic dish concentrator. The Stirling-cycle heat engine was identified as the conversion device for dish-electric with the most potential for meeting the program's goals for efficiency, reliability, and installed cost. To advance the technology toward commercialization, Sandia National Laboratories has acquired a Stirling Thermal Motors, Inc. kinematic Stirling engine, STM4-120, for evaluation. The engine is being bench-tested at Sandia's Engine Test Facility and will be combined later with a solar receiver for on-sun evaluation. This report presents the engine characteristics, finite element analyses of critical engine components, test system layout, instrumentation, and preliminary performance results from the bench test.

  20. Draft Test Guideline: Generic Freshwater Microcosm Test, Laboratory

    Science.gov (United States)

    The following draft test guideline is part of a series of test guidelines that have been developed by EPA for use in the testing of pesticides and toxic substances, and the development of test data for submission to the Agency for review.

  1. Smallpox Vaccination of Laboratory Workers at US Variola Testing Sites.

    Science.gov (United States)

    Medcalf, Sharon; Bilek, Laura; Hartman, Teresa; Iwen, Peter C; Leuschen, Patricia; Miller, Hannah; O'Keefe, Anne; Sayles, Harlan; Smith, Philip W

    2015-08-01

    To evaluate the need to revaccinate laboratory workers against smallpox, we assessed regular revaccination at the US Laboratory Response Network's variola testing sites by examining barriers to revaccination and the potential for persistence of immunity. Our data do not provide evidence to suggest prolonging the recommended interval for revaccination.

  2. Inadequate Information in Laboratory Test Requisition in a Tertiary ...

    African Journals Online (AJOL)

    Inadequate Information in Laboratory Test Requisition in a Tertiary Hospital in Benin City, ... Abstract. Aim: Laboratory investigations are important aspect of patient ... A total of 1786 (48.1%) of the request form had one or more incomplete or ...

  3. Effects of implant angulation, material selection, and impression technique on impression accuracy: a preliminary laboratory study.

    Science.gov (United States)

    Rutkunas, Vygandas; Sveikata, Kestutis; Savickas, Raimondas

    2012-01-01

    The aim of this preliminary laboratory study was to evaluate the effects of 5- and 25-degree implant angulations in simulated clinical casts on an impression's accuracy when using different impression materials and tray selections. A convenience sample of each implant angulation group was selected for both open and closed trays in combination with one polyether and two polyvinyl siloxane impression materials. The influence of material and technique appeared to be significant for both 5- and 25-degree angulations (P impression accuracy. The open-tray technique was more accurate with highly nonaxially oriented implants for the small sample size investigated.

  4. [The postcoital test: clinico-laboratory observations].

    Science.gov (United States)

    Stanislavov, R; Nalbanski, B; Pŭnevska, M

    1999-01-01

    The choice of optimal time, the technique and limitations of the post-coital test (PCT) have been described. They are of important significance for getting reliable information both concerning the cervical mucus, quality and migration of spermatozoa in female genital tract. It has been stressed that a negative PCT does not necessary exclude pregnancy. There are shown data for prognostic value of the PCT. The observation of more than 20 motility spermatozoa per HPF and higher frequency of pregnancy is common finding in comparison to low motility and number of spermatozoa in cervical mucus. The data support the hypothesis of "filtering" mechanism, excluding entrance of abnormal spermatozoa. Observing "shaking" phenomenon directs to searching immunological factor (local or systemic) against male gametes.

  5. In vitro tests to evaluate immunotoxicity: A preliminary study.

    NARCIS (Netherlands)

    Carfi', M; Gennari, A; Malerba, I; Corsini, E; Pallardy, M; Pieters, R; Loveren, Henk van; Vohr, H W; Hartung, T; Gribaldo, L

    2007-01-01

    The implementation of Registration, Evaluation and Authorisation of new and existing Chemicals (REACH) will increase the number of laboratory animals used, if alternative methods will not be available. In the meantime, REACH promotes the use of in vitro tests and, therefore, a set of appropriated al

  6. Design and preliminary testing of the RIC hybrid knee prosthesis.

    Science.gov (United States)

    Lenzi, T; Sensinger, J; Lipsey, J; Hargrove, L; Kuiken, T

    2015-08-01

    We present a novel hybrid knee prosthesis that uses a motor, transmission and control system only for active dynamics tasks, while relying on a spring/damper system for passive dynamics activities. Active dynamics tasks require higher torque, lower speed, and occur less frequently than passive dynamic activities. By designing the actuation system around active tasks alone, we achieved a lightweight design (1.7 Kg w/o battery) without sacrificing peak torque (85Nm repetitive). Preliminary tests performed by an able-bodied person using a bypass orthosis show that the hybrid knee can support reciprocal stairs ambulation with low electrical energy consumption.

  7. Preliminary Design of a LSA Aircraft Using Wind Tunnel Tests

    Directory of Open Access Journals (Sweden)

    Norbert ANGI

    2015-12-01

    Full Text Available This paper presents preliminary results concerning the design and aerodynamic calculations of a light sport aircraft (LSA. These were performed for a new lightweight, low cost, low fuel consumption and long-range aircraft. The design process was based on specific software tools as Advanced Aircraft Analysis (AAA, XFlr 5 aerodynamic and dynamic stability analysis, and Catia design, according to CS-LSA requirements. The calculations were accomplished by a series of tests performed in the wind tunnel in order to assess experimentally the aerodynamic characteristics of the airplane.

  8. Preliminary wind tunnel tests on the pedal wind turbine

    Science.gov (United States)

    Vinayagalingam, T.

    1980-06-01

    High solidity-low speed wind turbines are relatively simple to construct and can be used advantageously in many developing countries for such direct applications as water pumping. Established designs in this class, such as the Savonius and the American multiblade rotors, have the disadvantage that their moving surfaces require a rigid construction, thereby rendering large units uneconomical. In this respect, the pedal wind turbine recently reported by the author and which incorporates sail type rotors offers a number of advantages. This note reports preliminary results from a series of wind tunnel tests which were carried out to assess the aerodynamic torque and power characteristics of the turbine.

  9. Providing clinicians with information on laboratory test costs leads to ...

    African Journals Online (AJOL)

    Providing clinicians with information on laboratory test costs leads to ... Log in or Register to get access to full text downloads. ... For the intervention and control groups, pre- and postintervention cost and days in hospital were estimated.

  10. Potential of preliminary test methods to predict biodegradation performance of petroleum hydrocarbons in soil.

    Science.gov (United States)

    Aichberger, H; Hasinger, Marion; Braun, Rudolf; Loibner, Andreas P

    2005-03-01

    Preliminary tests at different scales such as degradation experiments (laboratory) in shaking flasks, soil columns and lysimeters as well as in situ respiration tests (field) were performed with soil from two hydrocarbon contaminated sites. Tests have been evaluated in terms of their potential to provide information on feasibility, degradation rates and residual concentration of bioremediation in the vadose zone. Sample size, costs and duration increased with experimental scale in the order shaking flasks - soil columns - lysimeter - in situ respiration tests, only time demand of respiration tests was relatively low. First-order rate constants observed in degradation experiments exhibited significant differences between both, different experimental sizes and different soils. Rates were in line with type and history of contamination at the sites, but somewhat overestimated field rates particularly in small scale experiments. All laboratory experiments allowed an estimation of residual concentrations after remediation. In situ respiration tests were found to be an appropriate pre-testing and monitoring tool for bioventing although residual concentrations cannot be predicted from in situ respiration tests. Moreover, this method does not account for potential limitations that might hamper biodegradation in the longer term but only reflects the actual degradation potential when the test is performed.

  11. Immediate needs for MQA testing at state secondary calibration laboratories

    Energy Technology Data Exchange (ETDEWEB)

    Cline, R. [Radiation Instrument Calibration Laboratory, Springfield, IL (United States)

    1993-12-31

    The Calibration Laboratory attempts to provide services that satisfy the needs and requests for a variety of customers. New needs and requests have resulted in calibration of instrumentation outside the original laboratory designs. These tasks require several changes at the laboratory and a need for new support services, especially measurement quality assurance (MQA). The MQA tests are gamma (Cs-137) below 0.5 mrem (5{mu}Sv) per hour and x-ray kVp. Modification to the current gamma (Cs-137) MQA test is recommended because lower intensity fields are commonly measured.

  12. Imaging and laboratory testing in acute abdominal pain.

    Science.gov (United States)

    Panebianco, Nova L; Jahnes, Katherine; Mills, Angela M

    2011-05-01

    When discussing which laboratory tests or imaging to order in the setting of acute abdominal pain, it is practical to organize information by disease process (eg, acute appendicitis, cholecystitis). Because studies on the accuracy of diagnostic tests are of necessity related to the presence or absence of specific diagnoses, and because clinicians frequently look to tests to help them rule in or rule out specific conditions, this article is organized by region of pain and common abdominal diagnoses. It focuses on the contributions that laboratory testing and imaging make in the emergency management of abdominal complaints. Copyright © 2011 Elsevier Inc. All rights reserved.

  13. Towards a rational antimicrobial testing policy in the laboratory

    Directory of Open Access Journals (Sweden)

    N Banaji

    2011-01-01

    Full Text Available Antimicrobial policy for prophylactic and therapeutic use of antimicrobials in a tertiary care setting has gained importance. A hospital′s antimicrobial policy as laid down by its hospital infection control team needs to include inputs from the microbiology laboratory, besides the pharmacy and therapeutic committee. Therefore, it is of utmost importance that clinical microbiologists across India follow international guidelines and also take into account local settings, especially detection and presence of resistance enzymes. This article draws a framework for rational antimicrobial testing in our laboratories in tertiary care centers, from the Clinical and Laboratory Standards Institute guidelines. It does not address testing methodologies but suggests ways and means by which antimicrobial susceptibility reporting can be rendered meaningful not only to the treating physician but also to the resistance monitoring epidemiologist. It hopes to initiate some standardization in rational choice of antimicrobial testing in laboratories in the country pertaining to nonfastidious bacteria.

  14. Towards a rational antimicrobial testing policy in the laboratory.

    Science.gov (United States)

    Banaji, N; Oommen, S

    2011-01-01

    Antimicrobial policy for prophylactic and therapeutic use of antimicrobials in a tertiary care setting has gained importance. A hospital's antimicrobial policy as laid down by its hospital infection control team needs to include inputs from the microbiology laboratory, besides the pharmacy and therapeutic committee. Therefore, it is of utmost importance that clinical microbiologists across India follow international guidelines and also take into account local settings, especially detection and presence of resistance enzymes. This article draws a framework for rational antimicrobial testing in our laboratories in tertiary care centers, from the Clinical and Laboratory Standards Institute guidelines. It does not address testing methodologies but suggests ways and means by which antimicrobial susceptibility reporting can be rendered meaningful not only to the treating physician but also to the resistance monitoring epidemiologist. It hopes to initiate some standardization in rational choice of antimicrobial testing in laboratories in the country pertaining to nonfastidious bacteria.

  15. The preliminary tests of the superconducting electron cyclotron resonance ion source DECRIS-SC2.

    Science.gov (United States)

    Efremov, A; Bekhterev, V; Bogomolov, S; Drobin, V; Loginov, V; Lebedev, A; Yazvitsky, N; Yakovlev, B

    2012-02-01

    A new compact version of the "liquid He-free" superconducting ECR ion source, to be used as an injector of highly charged heavy ions for the MC-400 cyclotron, is designed and built at the Flerov Laboratory of Nuclear Reactions in collaboration with the Laboratory of High Energy Physics of JINR. The axial magnetic field of the source is created by the superconducting magnet and the NdFeB hexapole is used for the radial plasma confinement. The microwave frequency of 14 GHz is used for ECR plasma heating. During the first tests, the source shows a good enough performance for the production of medium charge state ions. In this paper, we will present the design parameters and the preliminary results with gaseous ions.

  16. Design and preliminary test results of Daya Bay RPC modules*

    Energy Technology Data Exchange (ETDEWEB)

    Hackenburg, R.

    2011-09-01

    Resistive Plate Chamber (RPC) modules will be used as one part of the cosmic muon veto system in the Daya Bay reactor neutrino experiment. A total of 189 RPC modules will cover the three water pools in the experiment. To achieve track reconstruction and high efficiency, each module consists of 4 layers, each of which contains two sizes of bare chambers. The placement of bare chambers is reversed in different layers to reduce the overlapping dead areas. The module efficiency and patch efficiency were studied both in simulation and test of the data analysis. 143 modules have been constructed and tested. The preliminary study shows that the module and patch 3 out of 4 layers efficiency reaches about 98%.

  17. Design and preliminary test results of Daya Bay RPC modules

    Institute of Scientific and Technical Information of China (English)

    XU Ji-Lei; Logan Lebanowski; Cullen Newsom; Lin Shih-Kai; Jonathan Link; MA Lie-Hua; Viktor Pě(c); Vit Vorobel; CHEN Jin; LIU Jin-Chang; ZHOU Yong-Zhao; GUAN Meng-Yun; LIANG Hao; YANG Chang-Gen; WANG Yi-Fang; ZHANG Jia-Wen; LU Chang-Guo; Kirk McDonald; Robert Hackenburg; Kwong Lau

    2011-01-01

    Resistive Plate Chamber(RPC)modules will be used as one part of the cosmic muon veto system in the Days Bay reactor neutrino experiment.A total of 189 RPC modules will cover the three water pools in the experiment.To achieve track reconstruction and high efficiency,each module consists of 4 layers,each of which contains two sizes of bare chambers.The placement of bare chambers is reversed in different layers to reduce the overlapping dead areas.The module efficiency and patch efficiency were studied both in simulation and test of the data analysis.143 modules have been constructed and tested.The preliminary study shows that the module and patch 3 out of 4 layers efficiency reaches about 98%.

  18. Preliminary dimensioning of the IFMIF Tritium Release Test Module

    Energy Technology Data Exchange (ETDEWEB)

    Arbeiter, Frederik, E-mail: frederik.arbeiter@kit.edu; Abou-Sena, Ali; Chen, Yuming; Freund, Jana; Klix, Axel; Kondo, Keitaro; Vladimirov, Pavel

    2013-10-15

    Highlights: • The design of the IFMIF Tritium Release Test Module is explained. • Nuclear responses in the module and specimens are calculated. • Temperature fields during irradiation are calculated by 1D methods. • The tritium budget is calculated by 1D methods. -- Abstract: As part of the ongoing Engineering Validation and Engineering Design Activities for the International Fusion Materials Irradiation Facility (IFMIF), an experimental device suitable for the irradiation and online tritium release measurements of solid breeder ceramics and beryllium is investigated. This experimental device is called the Tritium Release Test Module (TRTM). In the preliminary design phase, the possible thermal conditions, the tritium diffusion budgets, and the mechanical loads have been studied by analytical calculations and numerical codes. The most important results concern the tritium production and nuclear heating induced in the structures, the temperature distribution in the specimen region and the structure, and the diffusion of tritium through the safety barriers.

  19. Problems and solutions in laboratory testing for hemophilia.

    Science.gov (United States)

    Favaloro, Emmanuel J; Meijer, Piet; Jennings, Ian; Sioufi, John; Bonar, Roslyn A; Kitchen, Dianne P; Kershaw, Geoffrey; Lippi, Giuseppe

    2013-10-01

    A diagnosis of hemophilia A or hemophilia B begins with clinical assessment of the patient and is facilitated by laboratory testing. The influence of the latter on a diagnosis of hemophilia A or hemophilia B is clear-a diagnosis cannot be made without laboratory confirmation of a deficiency of factor FVIII (FVIII) or factor IX (FIX), respectively. Moreover, the degree of hemophilia severity is specifically characterized by laboratory test results. In turn, patient management, including choice and application of therapies, is influenced by the diagnosis, as well as by identification of respective disease severity. An incorrect diagnosis may lead to inappropriate management and unnecessary therapy, and thus to adverse outcomes. Moreover, identification of factor inhibitors in hemophilia will lead to additional and differential treatments, and incorrect identification of inhibitors or inhibitor levels may also lead to inappropriate management. Problems in hemophilia diagnosis or inhibitor detection can occur at any stage in the clinical diagnosis/laboratory interface, from the "pre-preanalytical" to "preanalytical" to "analytical" to "postanalytical" to "post-postanalytical." This report outlines the various problems in laboratory testing for hemophilia and provides various strategies or solutions to overcome these challenges. Although some outlined solutions are specific to the potential errors related to hemophilia, others are general in nature and can be applied to other areas of laboratory hemostasis. Key to improvement in this area is adoption of best practice by all involved, including clinicians, phlebotomists, and laboratories. Also key is the recognition that such errors may occur, and thus that clinicians should assess laboratory test results in the context of their patient's clinical history and follow-up any potential errors, thus avoid misdiagnoses, by requesting repeat testing on a fresh sample.

  20. System Quality Management in Software Testing Laboratory that Chooses Accreditation

    Directory of Open Access Journals (Sweden)

    Yanet Brito R.

    2013-12-01

    Full Text Available The evaluation of software products will reach full maturity when executed by the scheme and provides third party certification. For the validity of the certification, the independent laboratory must be accredited for that function, using internationally recognized standards. This brings with it a challenge for the Industrial Laboratory Testing Software (LIPS, responsible for testing the products developed in Cuban Software Industry, define strategies that will permit it to offer services with a high level of quality. Therefore it is necessary to establish a system of quality management according to NC-ISO/IEC 17025: 2006 to continuously improve the operational capacity and technical competence of the laboratory, with a view to future accreditation of tests performed. This article discusses the process defined in the LIPS for the implementation of a Management System of Quality, from the current standards and trends, as a necessary step to opt for the accreditation of the tests performed.

  1. Deep Borehole Field Test Laboratory and Borehole Testing Strategy

    Energy Technology Data Exchange (ETDEWEB)

    Kuhlman, Kristopher L. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Brady, Patrick V. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); MacKinnon, Robert J. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Heath, Jason E. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Herrick, Courtney G. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Jensen, Richard P. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Gardner, W. Payton [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Sevougian, S. David [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Bryan, Charles R. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Jang, Je-Hun [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Stein, Emily R. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Bauer, Stephen J. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Daley, Tom [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Freifeld, Barry M. [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Birkholzer, Jens [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Spane, Frank A. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States)

    2016-09-19

    Deep Borehole Disposal (DBD) of high-level radioactive wastes has been considered an option for geological isolation for many years (Hess et al. 1957). Recent advances in drilling technology have decreased costs and increased reliability for large-diameter (i.e., ≥50 cm [19.7”]) boreholes to depths of several kilometers (Beswick 2008; Beswick et al. 2014). These advances have therefore also increased the feasibility of the DBD concept (Brady et al. 2009; Cornwall 2015), and the current field test design will demonstrate the DBD concept and these advances. The US Department of Energy (DOE) Strategy for the Management and Disposal of Used Nuclear Fuel and High-Level Radioactive Waste (DOE 2013) specifically recommended developing a research and development plan for DBD. DOE sought input or expression of interest from States, local communities, individuals, private groups, academia, or any other stakeholders willing to host a Deep Borehole Field Test (DBFT). The DBFT includes drilling two boreholes nominally 200m [656’] apart to approximately 5 km [16,400’] total depth, in a region where crystalline basement is expected to begin at less than 2 km depth [6,560’]. The characterization borehole (CB) is the smaller-diameter borehole (i.e., 21.6 cm [8.5”] diameter at total depth), and will be drilled first. The geologic, hydrogeologic, geochemical, geomechanical and thermal testing will take place in the CB. The field test borehole (FTB) is the larger-diameter borehole (i.e., 43.2 cm [17”] diameter at total depth). Surface handling and borehole emplacement of test package will be demonstrated using the FTB to evaluate engineering feasibility and safety of disposal operations (SNL 2016).

  2. Laboratory Diagnostics Market in East Africa: A Survey of Test Types, Test Availability, and Test Prices in Kampala, Uganda.

    Directory of Open Access Journals (Sweden)

    Lee F Schroeder

    Full Text Available Diagnostic laboratory tests are routinely defined in terms of their sensitivity, specificity, and ease of use. But the actual clinical impact of a diagnostic test also depends on its availability and price. This is especially true in resource-limited settings such as sub-Saharan Africa. We present a first-of-its-kind report of diagnostic test types, availability, and prices in Kampala, Uganda.Test types (identity and availability were based on menus and volumes obtained from clinical laboratories in late 2011 in Kampala using a standard questionnaire. As a measure of test availability, we used the Availability Index (AI. AI is the combined daily testing volumes of laboratories offering a given test, divided by the combined daily testing volumes of all laboratories in Kampala. Test prices were based on a sampling of prices collected in person and via telephone surveys in 2015.Test volumes and menus were obtained for 95% (907/954 of laboratories in Kampala city. These 907 laboratories offered 100 different test types. The ten most commonly offered tests in decreasing order were Malaria, HCG, HIV serology, Syphilis, Typhoid, Urinalysis, Brucellosis, Stool Analysis, Glucose, and ABO/Rh. In terms of AI, the 100 tests clustered into three groups: high (12 tests, moderate (33 tests, and minimal (55 tests availability. 50% and 36% of overall availability was provided through private and public laboratories, respectively. Point-of-care laboratories contributed 35% to the AI of high availability tests, but only 6% to the AI of the other tests. The mean price of the most commonly offered test types was $2.62 (range $1.83-$3.46.One hundred different laboratory test types were in use in Kampala in late 2011. Both public and private laboratories were critical to test availability. The tests offered in point-of-care laboratories tended to be the most available tests. Prices of the most common tests ranged from $1.83-$3.46.

  3. Laboratory Diagnostics Market in East Africa: A Survey of Test Types, Test Availability, and Test Prices in Kampala, Uganda.

    Science.gov (United States)

    Schroeder, Lee F; Elbireer, Ali; Jackson, J Brooks; Amukele, Timothy K

    2015-01-01

    Diagnostic laboratory tests are routinely defined in terms of their sensitivity, specificity, and ease of use. But the actual clinical impact of a diagnostic test also depends on its availability and price. This is especially true in resource-limited settings such as sub-Saharan Africa. We present a first-of-its-kind report of diagnostic test types, availability, and prices in Kampala, Uganda. Test types (identity) and availability were based on menus and volumes obtained from clinical laboratories in late 2011 in Kampala using a standard questionnaire. As a measure of test availability, we used the Availability Index (AI). AI is the combined daily testing volumes of laboratories offering a given test, divided by the combined daily testing volumes of all laboratories in Kampala. Test prices were based on a sampling of prices collected in person and via telephone surveys in 2015. Test volumes and menus were obtained for 95% (907/954) of laboratories in Kampala city. These 907 laboratories offered 100 different test types. The ten most commonly offered tests in decreasing order were Malaria, HCG, HIV serology, Syphilis, Typhoid, Urinalysis, Brucellosis, Stool Analysis, Glucose, and ABO/Rh. In terms of AI, the 100 tests clustered into three groups: high (12 tests), moderate (33 tests), and minimal (55 tests) availability. 50% and 36% of overall availability was provided through private and public laboratories, respectively. Point-of-care laboratories contributed 35% to the AI of high availability tests, but only 6% to the AI of the other tests. The mean price of the most commonly offered test types was $2.62 (range $1.83-$3.46). One hundred different laboratory test types were in use in Kampala in late 2011. Both public and private laboratories were critical to test availability. The tests offered in point-of-care laboratories tended to be the most available tests. Prices of the most common tests ranged from $1.83-$3.46.

  4. ADDITIVE TESTING FOR IMPROVED SULFUR RETENTION: PRELIMINARY REPORT

    Energy Technology Data Exchange (ETDEWEB)

    Amoroso, J.; Fox, K.

    2011-09-07

    The Savannah River National Laboratory is collaborating with Alfred University to evaluate the potential for additives in borosilicate glass to improve sulfur retention. This preliminary report provides further background on the incorporation of sulfur in glass and outlines the experiments that are being performed by the collaborators. A simulated waste glass composition has been selected for the experimental studies. The first phase of experimental work will evaluate the impacts of BaO, PbO, and V{sub 2}O{sub 5} at concentrations of 1.0, 2.0, and 5.0 wt % on sulfate retention in simulated high level waste borosilicate glass. The second phase of experimental work will evaluate the effects of time at the melt temperature on sulfur retention. The resulting samples will be characterized to determine the amount of sulfur remaining as well as to identify the formation of any crystalline phases. The results will be used to guide the future selection of frits and glass forming chemicals in vitrifying Department of Energy wastes containing high sulfur concentrations.

  5. Results of Preliminary Tests of PAR Bunch Cleaning

    CERN Document Server

    Yao, Chihyuan; Grelick, Arthur; Lumpkin, Alex H; Sereno, Nicholas S

    2005-01-01

    A particle accumulator ring (PAR) is used at the Advanced Photon Source (APS) to collect multiple linac bunches and compress them into a 0.3-ns (rms) single bunch for booster injection. A 9.77-MHz fundamental rf system and a 117.3-MHz harmonic rf system are employed for initial beam capture and bunch length compression. Satellite bunches with very low charge form due to rf phase drifts or beam loading change. These satellites, when injected into the booster and then into the storage ring (SR), cause bunch impurity at three buckets from the target bucket. Storage ring and booster bunch cleaning was tried but proved to be difficult due to the top-up mode of operation in the storage ring and tune drift in the booster synchrotron. Recently we implemented a PAR bunch-cleaning system with tune-modulated harmonic rf knockout. Preliminary tests gave a measured SR bunch purity of better than 10

  6. Installation of ECR2 at LNS and Preliminary tests

    CERN Document Server

    Gammino, S; Ciavola, G; Castro, M; Chines, F; Marletta, S; Bieth, C; Sortais, P; Kantas, S

    1999-01-01

    The source ECR2 has been built in 1998 by Pantechnik, according to the design suggested by LNS Ion Source Group. This design entails some improvements with respect to a standard CAPRICE-type source: a) the magnetic field (up to 1.6 T axial, 1.1 T radial) allows to operate the source at 14 GHz in High B mode and at 18 GHz; b) two frequency heating can be used; c) an aluminum made plasma chamber is used in place of the stainless steel one. The main features of ECR2 along with a review of the preliminary tests will be outlined. Typical currents for fully stripped nitrogen are about 25 emA; for the heaviest ions, 1 emA of Kr28+ and 10 emA of Ta27+ have been measured. The installation at LNS has been completed recently and the details will be given.

  7. Model Testing - Bringing the Ocean into the Laboratory

    DEFF Research Database (Denmark)

    Aage, Christian

    2000-01-01

    Hydrodynamic model testing, the principle of bringing the ocean into the laboratory to study the behaviour of the ocean itself and the response of man-made structures in the ocean in reduced scale, has been known for centuries. Due to an insufficient understanding of the physics involved, however......, the early model tests often gave incomplete or directly misleading results.This keynote lecture deals with some of the possibilities and problems within the field of hydrodynamic and hydraulic model testing....

  8. Finding neurosyphilis without the Venereal Disease Research Laboratory test.

    Science.gov (United States)

    MacLean, S; Luger, A

    1996-01-01

    The cerebrospinal fluid (CSF)-Venereal Disease Research Laboratory (VDRL) test is only 27% sensitive for diagnosing neurosyphilis. Discriminant analysis, used on 124 patients, shows that other commonly used laboratory tests can, in combination, identify 87% of patients with neurosyphilis with 94% specificity. The insensitivity of the CSF-VDRL (27% in persons with neurosyphilis) and the foreseen greater need to identify and treat neurosyphilis in the era of human immunodeficiency virus caused us to analyze the serum and cerebrospinal fluid results of 73 patients with syphilis and of 51 patients with clinically diagnosed neurosyphilis. Discriminant analysis was applied to different sets of laboratory tests to find the combination of test results best able to predict retrospectively the clinical diagnosis of syphilis or neurosyphilis, without reference to the CSF-VDRL. The predicting function averages 94% specificity and 87% sensitivity. Test result variables considered together are: CSF-FTA-ABS, serum FTA-ABS, CSF-TPHA, serum TPHA, and CSF cells. The authors conclude that clinicians or laboratories can, independently of the CSF-VDRL, compute a score showing whether the results of a set of commonly used tests suggest neurosyphilis in a patient.

  9. The preliminary results of fast neutron flux measurements in the DULB laboratory at Baksan

    CERN Document Server

    Abdurashitov, J N; Kalikhov, A V; Shikhin, A A; Yants, V E; Zaborskaia, O S; Klimenko, A A; Osetrov, S B; Smolnikov, A A; Vasilev, S I

    2000-01-01

    One of the main sources of a background in underground physics experiments (such as the investigation of solar neutrino flux, neutrino oscillations, neutrinoless double beta decay, and the search for annual and daily Cold Dark Matter particle flux modulation) are fast neutrons originating from the surrounding rocks. The measurements of fast neutron flux in the new DULB Laboratory situated at a depth of 4900 m w.e. in the Baksan Neutrino Observatory have been performed. The relative neutron shielding properties of several commonly available natural materials were investigated too. The preliminary results obtained with a high-sensitive fast neutron spectrometer at the level of sensitivity of about 10^(-7) neutron/ (cm^2 sec) are presented and discussed.

  10. Post-depositional changes in snow isotope content: preliminary results of laboratory experiments

    Directory of Open Access Journals (Sweden)

    A. A. Ekaykin

    2009-10-01

    Full Text Available Isotopic content of the snow and firn thickness is assumed to be altered significantly due to the post-depositional (PD mass- and isotope exchange with the atmospheric water vapor. If so, these effects should be accounted for in the ice core-based isotope-temperature paleo-reconstructions. In order to study the intensity of the PD processes we set up a series of laboratory experiments. In this paper we describe in detail the experimental technique and briefly overview preliminary results. It is shown that the PD modifications in the upper layer of snow thickness are noticeably strong even under such a low temperature as −35°C (the value typical for the Central Antarctic summer. It is demonstrated that the PD isotopic changes in snow can be approximated as a linear function of the relative mass loss due to snow sublimation. Possible applications for improving the isotope-temperature paleo-reconstructions are shortly discussed.

  11. A preliminary survey of the National Wetlands Inventory as mapped for the Idaho National Engineering Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Hampton, N.L.; Rope, R.C.; Glennon, J.M.; Moor, K.S.

    1995-02-01

    Approximately 135 areas within the boundaries of the Idaho National Engineering Laboratory (INEL) have been mapped as wetland habitat as part of the United States Fish and Wildlife Service (FWS) National Wetlands Inventory (NWI). A preliminary survey of these wetlands was conducted to examine their general characteristics and status, to provide an estimation of relative ecological importance, to identify additional information needed to complete ecological characterization of important INEL wetlands, and to identify high priority wetland areas on the INEL. The purpose of the survey was to provide information to support the preparation of the Environmental Restoration and Waste Management (ER&WM) Environmental Impact Statement (EIS). Information characterizing general vegetation, hydrology, wildlife use, and archaeology was collected at 105 sample sites on the INEL. Sites representing NWI palustrine, lacustrine, and riverine wetlands (including manmade), and areas unmapped or unclassified by the NWI were included in the sample. The field information was used to develop a preliminary ranking of relative ecological importance for each wetland visited during this survey. Survey limitations are identified.

  12. Quality performance of laboratory testing in pharmacies: a collaborative evaluation.

    Science.gov (United States)

    Zaninotto, Martina; Miolo, Giorgia; Guiotto, Adriano; Marton, Silvia; Plebani, Mario

    2016-11-01

    The quality performance and the comparability between results of pharmacies point-of-care-testing (POCT) and institutional laboratories have been evaluated. Eight pharmacies participated in the project: a capillary specimen collected by the pharmacist and, simultaneously, a lithium-heparin sample drawn by a physician of laboratory medicine for the pharmacy customers (n=106) were analyzed in the pharmacy and in the laboratory, respectively. Glucose, cholesterol, HDL-cholesterol, triglycerides, creatinine, uric acid, aspartate aminotransferase, alanine aminotransferase, were measured using: Reflotron, n=5; Samsung, n=1; Cardiocheck PA, n=1; Cholestech LDX, n=1 and Cobas 8000. The POCT analytical performance only (phase 2) were evaluated testing, in pharmacies and in the laboratory, the lithium heparin samples from a female drawn fasting daily in a week, and a control sample containing high concentrations of glucose, cholesterol and triglycerides. For all parameters, except triglycerides, the slopes showed a satisfactory correlation. For triglycerides, a median value higher in POCT in comparison to the laboratory (1.627 mmol/L vs. 0.950 mmol/L) has been observed. The agreement in the subjects classification, demonstrates that for glucose, 70% of the subjects show concentrations below the POCT recommended level (5.8-6.1 mmol/L), while 56% are according to the laboratory limit (pharmacies and specific criticisms in the pre- and post-analytical phases.

  13. Duplicated laboratory tests: evaluation of a computerized alert intervention abstract.

    Science.gov (United States)

    Bridges, Sharon A; Papa, Linda; Norris, Anne E; Chase, Susan K

    2014-01-01

    Redundant testing contributes to reductions in healthcare system efficiency. The purpose of this study was to: (1) determine if the use of a computerized alert would reduce the number and cost of duplicated Acute Hepatitis Profile (AHP) laboratory tests and (2) assess what patient, test, and system factors were associated with duplication. This study used a quasi-experimental pre- and post-test design to determine the proportion of duplication of the AHP test before and after implementation of a computerized alert intervention. The AHP test was duplicated if the test was requested again within 15 days of the initial test being performed and the result present in the medical record. The intervention consisted of a computerized alert (pop-up window) that indicated to the clinician that the test had recently been ordered. A total of 674 AHP tests were performed in the pre-intervention period and 692 in the postintervention group. In the pre-intervention period, 53 (7.9%) were duplicated and in postintervention, 18 (2.6%) were duplicated (ptests (p≤.001). Implementation of computerized alerts may be useful in reducing duplicate laboratory tests and improving healthcare system efficiency.

  14. Compendium of Test Results of Recent Single Event Effect Tests Conducted by the Jet Propulsion Laboratory

    Science.gov (United States)

    McClure, Steven S.; Allen, Gregory R.; Irom, Farokh; Scheick, Leif Z.; Adell, Philippe C.; Miyahira, Tetsuo F.

    2010-01-01

    This paper reports heavy ion and proton-induced single event effect (SEE) results from recent tests for a variety of microelectronic devices. The compendium covers devices tested over the last two years by the Jet Propulsion Laboratory.

  15. Thick Concrete Specimen Construction, Testing, and Preliminary Analysis

    Energy Technology Data Exchange (ETDEWEB)

    Clayton, Dwight A. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Hoegh, Kyle [Univ. of Minnesota, Minneapolis, MN (United States); Khazanovich, Lev [Univ. of Minnesota, Minneapolis, MN (United States)

    2015-03-01

    The purpose of the U.S. Department of Energy Office of Nuclear Energy’s Light Water Reactor Sustainability (LWRS) Program is to develop technologies and other solutions that can improve the reliability, sustain the safety, and extend the operating lifetimes of nuclear power plants (NPPs) beyond 60 years. Since many important safety structures in an NPP are constructed of concrete, inspection techniques must be developed and tested to evaluate the internal condition. In-service containment structures generally do not allow for the destructive measures necessary to validate the accuracy of these inspection techniques. This creates a need for comparative testing of the various nondestructive evaluation (NDE) measurement techniques on concrete specimens with known material properties, voids, internal microstructure flaws, and reinforcement locations. A preliminary report detailed some of the challenges associated with thick reinforced concrete sections and prioritized conceptual designs of specimens that could be fabricated to represent NPP concrete structures for using in NDE evaluation comparisons. This led to the construction of the concrete specimen presented in this report, which has sufficient reinforcement density and cross-sectional size to represent an NPP containment wall. Details on how a suitably thick concrete specimen was constructed are presented, including the construction materials, final nominal design schematic, as well as formwork and rigging required to safely meet the desired dimensions of the concrete structure. The report also details the type and methods of forming the concrete specimen as well as information on how the rebar and simulated defects were embedded. Details on how the resulting specimen was transported, safely anchored, and marked to allow access for systematic comparative NDE testing of defects in a representative NPP containment wall concrete specimen are also given. Data collection using the MIRA Ultrasonic NDE equipment and

  16. Safety in the Chemical Laboratory: Tested Disposal Methods for Chemical Wastes from Academic Laboratories.

    Science.gov (United States)

    Armour, M. A.; And Others

    1985-01-01

    Describes procedures for disposing of dichromate cleaning solution, picric acid, organic azides, oxalic acid, chemical spills, and hydroperoxides in ethers and alkenes. These methods have been tested under laboratory conditions and are specific for individual chemicals rather than for groups of chemicals. (JN)

  17. Results of Laboratory Testing of Advanced Power Strips

    Energy Technology Data Exchange (ETDEWEB)

    Earle, L. [National Renewable Energy Lab. (NREL), Golden, CO (United States); Sparn, B. [National Renewable Energy Lab. (NREL), Golden, CO (United States)

    2012-08-01

    Presented at the ACEEE Summer Study on Energy Efficiency in Buildings on August 12-17, 2012, this presentation reports on laboratory tests of 20 currently available advanced power strip products, which reduce wasteful electricity use of miscellaneous electric loads in buildings.

  18. Preliminary laboratory studies of the optical scattering properties of the crystal clouds

    Directory of Open Access Journals (Sweden)

    C. Saunders

    Full Text Available Ice crystal clouds have an influence on the radiative budget of the earth; however, the exact size and nature of this influence has yet to be determined. A laboratory cloud chamber experiment has been set up to provide data on the optical scattering behaviour of ice crystals at a visible wavelength in order to gain information which can be used in climate models concerning the radiative characteristics of cirrus clouds. A PMS grey-scale probe is used to monitor simultaneously the cloud microphysical properties in order to correlate these closely with the observed radiative properties. Preliminary results show that ice crystals scatter considerably more at 90° than do water droplets, and that the halo effects are visible in a laboratory-generated cloud when the ice crystal concentration is sufficiently small to prevent masking from multiple scattering.

    Key words. Meteorology and atmosphere dynamics · Climatology · Radiative process · Atmospheric composition and structure · Cloud physics and chemistry

  19. Environmental Survey preliminary report, Oak Ridge National Laboratory (X-10), Oak Ridge, Tennessee

    Energy Technology Data Exchange (ETDEWEB)

    1988-07-01

    This report presents the preliminary findings from the first phase of the Environmental Survey of the US Department of Energy (DOE) Oak Ridge National Laboratory (ORNL), X-10 site, conducted August 17 through September 4, 1987. The Survey is being conducted by an interdisciplinary team of environmental specialists, led and managed by the Office of Environment, Safety and Health's Office of Environmental Audit. Individual team specialists are outside experts supplied by a private contractor. The objective of the Survey is to identify environmental problems and areas of environmental risk associated with ORNL. The Survey covers all environmental media and all areas of environmental regulation. It is being performed in accordance with the DOE Environmental Survey Manual. The on-site phase of the Survey involves the review of existing site environmental data, observations of the operations carried on at ORNL, and interviews with site personnel. The Survey team developed a Sampling and Analysis Plan to assist in further assessing certain of the environmental problems identified during its on-site activities. The Sampling and Analysis Plan will be executed by a DOE National Laboratory or a support contractor. When completed, the results will be incorporated into the Environmental Survey Interim Report for ORNL. The Interim Report will reflect the final determinations of the ORNL Survey. 120 refs., 68 figs., 71 tabs.

  20. Environmental Survey preliminary report, Los Alamos National Laboratory, Los Alamos, New Mexico

    Energy Technology Data Exchange (ETDEWEB)

    1988-01-01

    This report presents the preliminary findings from the first phase of the Environmental Survey of the United States Department of Energy's (DOE) Los Alamos National Laboratory (LANL), conducted March 29, 1987 through April 17, 1987. The Survey is being conducted by an interdisciplinary team of environmental specialists, led and managed by the Office of Environment, Safety and Health's Office of Environmental Audit. Individual team components are outside experts being supplied by a private contractor. The objective of the Survey is to identify environmental problems and areas of environmental risk associated with the LANL. The Survey covers all environmental media and all areas of environmental regulation. It is being performed in accordance with the DOE Environmental Survey Manual. The on-site phase of the Survey involves the review of existing site environmental data, observations of the operations carried on at the LANL, and interviews with site personnel. The Survey team developed Sampling and Analysis Plan to assist in further assessing certain of the environmental problems identified during its on-site activities. The Sampling and Analysis Plan will be executed by the Idaho National Engineering Laboratory. When completed, the results will be incorporated into the LANL Environmental Survey Interim Report. The Interim Report will reflect the final determinations of the Survey for the LANL. 65 refs., 68 figs., 73 tabs.

  1. Environmental Survey preliminary report, Laboratory for Energy-Related Health Research, Davis, California

    Energy Technology Data Exchange (ETDEWEB)

    1988-03-01

    This report presents the preliminary findings from the first phase of the Survey of the United States Department of Energy (DOE) Laboratory for Energy-Related Health Research (LEHR) at the University of California, Davis (UC Davis), conducted November 16 through 20, 1987. The Survey is being conducted by an interdisciplinary team of environmental specialists, led and managed by the Office of Environment, Safety and Health's Office of Environmental Audit. Individual team components are being supplied by a private contractor. The objective of the Survey is to identify environmental problems and areas of environmental risk associated with the LEHR. The Survey covers all environmental media and all areas of environmental regulation, and is being performed in accordance with the DOE Environmental Survey Manual. This phase of the Survey involves the review of existing site environmental data, observations of the operations at the LEHR and interviews with site personnel. The Survey team developed a Sampling and Analysis Plan to assist in further assessing certain of the environmental problems identified during its on-site activities. The Sampling and Analysis Plan will be executed by a DOE National Laboratory or a support contractor. When completed, the results will be incorporated into the Environmental Survey Interim Report for the LEHR at UC Davis. The Interim Report will reflect the final determinations of the LEHR Survey. 75 refs., 26 figs., 23 tabs.

  2. Environmental Survey preliminary report, Princeton Plasma Physics Laboratory, Princeton, New Jersey

    Energy Technology Data Exchange (ETDEWEB)

    1989-05-01

    This report presents the preliminary findings of the first phase of the Environmental Survey of the United States Department of Energy's (DOE) Princeton Plasma Physics Laboratory (PPPL), conducted June 13 through 17, 1988. The Survey is being conducted by an interdisciplinary team of environmental specialists, led and managed by the Office of Environment, Safety and Health's Office of Environmental Audit. Team members are being provided by private contractors. The objective of the Survey is to identify environmental problems and areas of environmental risk associated with PPPL. The Survey covers all environmental media and all areas of environmental regulation. It is being performed in accordance with the DOE Environmental Survey Manual. This phase of the Survey involves the review of existing site environmental data, observations of the operations carried on at PPPL, and interviews with site personnel. The Survey team developed a Sampling and Analysis (S A) Plan to assist in further assessing certain of the environment problems identified during its on-site activities. The S A plan is being developed by the Idaho National Engineering Laboratory. When completed, the S A results will be incorporated into the PPPL Survey findings for inclusion in the Environmental Survey Summary Report. 70 refs., 17 figs., 21 tabs.

  3. Preliminary correlations of feature strength in spark-induced breakdown spectroscopy of bioaerosols with concentrations measured in laboratory analyses

    Energy Technology Data Exchange (ETDEWEB)

    Schmidt, Morgan S.; Bauer, Amy J. Ray

    2010-05-01

    We present preliminary results that show good correlation between elemental compositions of three bioaerosol samples, as measured in the laboratory by combustion analysis and with proton-induced x-ray emission and spark-induced breakdown spectroscopy signals integrated over the entire emission time profiles. Atomic (Ca, Al, Fe, and Si) and molecular features (CN, N2{sup +}, and OH) were observed compared to the laboratory data.

  4. Verification and validation of diagnostic laboratory tests in clinical virology.

    Science.gov (United States)

    Rabenau, Holger F; Kessler, Harald H; Kortenbusch, Marhild; Steinhorst, Andreas; Raggam, Reinhard B; Berger, Annemarie

    2007-10-01

    This review summarizes major issues of verification and validation procedures and describes minimum requirements for verification and validation of diagnostic assays in clinical virology including instructions for CE/IVD-labeled as well as for self-developed ("home-brewed") tests or test systems. It covers techniques useful for detection of virus specific antibodies, for detection of viral antigens, for detection of viral nucleic acids, and for isolation of viruses on cell cultures in the routine virology laboratory.

  5. How to test NISP instrument for EUCLID mission in laboratory

    DEFF Research Database (Denmark)

    Costille, A.; Carle, Michael; Fabron, Christophe;

    2016-01-01

    . To achieve these tests campaign, a global Ground Support Equipment (GSE) called the Verification Ground System (VGS) has to be developed. It will be a complex set of GSE integrated in ERIOS chamber made of: a telescope simulator to simulate the EUCLID telescope and to inject light into NISP, a thermal...... will present the preliminary design and concepts of the VGS and we will show the main difficulties we have to deal with: design of thermal environment at 80K with 4mK stability, the development of a metrology system in vacuum, knowledge of the focus position within 150μm in cold, etc. The main objectives...

  6. Performance testing of radiobioassay laboratories: In vivo measurements, Final Report

    Energy Technology Data Exchange (ETDEWEB)

    MacLellan, J.A.; Traub, R.J.; Olsen, P.C.

    1990-04-01

    A study of two rounds of in vivo laboratory performance testing was undertaken by Pacific Northwest Laboratory (PNL) to determine the appropriateness of the in vivo performance criteria of draft American National Standards Institute (ANSI) standard ANSI N13.3, Performance Criteria for Bioassay.'' The draft standard provides guidance to in vivo counting facilities regarding the sensitivity, precision, and accuracy of measurements for certain categories of commonly assayed radionuclides and critical regions of the body. This report concludes the testing program by presenting the results of the Round Two testing. Testing involved two types of measurements: chest counting for radionuclide detection in the lung, and whole body counting for detection of uniformly distributed material. Each type of measurement was further divided into radionuclide categories as defined in the draft standard. The appropriateness of the draft standard criteria by measuring a laboratory's ability to attain them were judged by the results of both round One and Round Two testing. The testing determined that performance criteria are set at attainable levels, and the majority of in vivo monitoring facilities passed the criteria when complete results were submitted. 18 refs., 18 figs., 15 tabs.

  7. [Peritoneal equilibration test: Conventional versus adapted. Preliminary study].

    Science.gov (United States)

    Zaloszyc, Ariane; Schmitt, Claus Peter; Schaefer, Betti; Doutey, Armelle; Terzic, Joëlle; Menouer, Soraya; Higel, Laetitia; Fischbach, Michel

    2017-02-01

    Conventional automated peritoneal dialysis (APD) is prescribed as a repetition of cycles with the same dwell time and the same fill volume. Water and sodium balance remains a common problem among patients on peritoneal dialysis. More recently, adapted automated peritoneal dialysis was described, as a combination of short dwells with a low volume, in order to enhance ultrafiltration, followed by long dwells with a large fill volume to favor solute removal. We performed a preliminary crossover study on 4 patients. The total amount of dialysate was the same, i.e. 2L/m(2) as well as the total duration of the test, i.e. 150 minutes. The conventional test was made with two identical cycles, each cycle had a fill volume of 1L/m(2) and a duration of 75 minutes, while the adapted test was performed with one short cycle, i.e. 30 minutes with a low fill volume, i.e. 0.6L/m(2), followed by a long cycle, i.e. 120 minutes, with a large fill volume, i.e. 1.4L/m(2). Sodium extraction was improved by 29.3mmol/m(2) (169%) in the adapted test in comparison to the conventional test. Ultrafiltration was enhanced by 159mL/m(2) (128%) in the adapted test compared to the conventional one. Glucose absorption was decreased by 35% in the adapted test in comparison to the conventional test and osmotic conductance was also improved. In conclusion, adapted dialysis may allow for a better volume and sodium balance, since we observed an improvement in sodium extraction and ultrafiltration. This pre-study authorizes an improvement of the European Pediatric Study's protocol on Adapted APD, already started and which will continue in the next months. Copyright © 2016 Association Société de néphrologie. Published by Elsevier SAS. All rights reserved.

  8. [Point-of-care-testing--the intensive care laboratory].

    Science.gov (United States)

    Müller, M M; Hackl, W; Griesmacher, A

    1999-01-01

    After successful centralization of laboratory analyses since more than 30 years, advances in biosensors, microprocessors, measurement of undiluted whole blood and miniaturization of laboratory analyzers are leading nowadays more and more to a re-decentralization in the laboratory medicine. Point-of-care-testing (POCT), which is defined as any laboratory test performed outside central or decentralized laboratories, is becoming more and more popular. The theoretical advantages of POCT are faster turn-around-times (TAT), more rapid medical decisions, avoidance of sample identification and sample transport problems and the need of only small specimen volumes. These advantages are frequently mentioned, but are not associated with a clear clinical benefit. The disadvantages of POCT such as incorrect handling and/or maintenance of the analyzers by nontrained clinical staff, inadequate or even absent calibrations and/or quality controls, lack of cost-effectiveness because of an increased number of analyzers and more expensive reagents, insufficient documentation and difficult comparability of the obtained POCT-results with routine laboratory results, are strongly evident. According to the authors' opinion the decision for the establishing of POCT has only to be made in a close co-operation between physicians and laboratorians in order to vouch for necessity and high quality of the analyses. Taking the local situation into consideration (24-h-central laboratory, etc.) the spectrum of parameters measured by means of POCT should be rigorously restricted to the vital functions. Such analytes should be: hemoglobin or hematocrit, activated whole blood clotting time, blood gases, sodium, potassium, ionized calcium, glucose, creatinine, ammonia and lactate.

  9. Preliminary report on the ecological assessment of Waste Area Grouping 5 at Oak Ridge National Laboratory, Oak Ridge, Tennessee

    Energy Technology Data Exchange (ETDEWEB)

    Ashwood, T.L.; Suter, G.W. II; Stewart, A.J.

    1992-09-01

    In support of the remedial investigation for Waste Area Grouping (WAG) 5, staff of the Environmental Sciences Division of Oak Ridge National Laboratory have conducted preliminary ecological assessment activities. A screening level ecological risk assessment has been completed, ambient toxicity tests have been conducted on streams and seeps within WAG 5, WAG 5 has been surveyed for rare and endangered species and wetlands, and wild turkeys that may feed on contaminated vegetation and insects in WAG 5 have been screened for beta-emitting isotopes and [sup 137]Cs. The screening-level ecological risk assessment identified some data gaps that were addressed in the ecological assessment plan. These include gaps in data on the toxicity of surface water and soil within WAG 5 and on the status of rare and endangered species. In addition, the screening-level risk assessment identified the need for data on the level of contaminants in wild turkeys that may be consumed by predatory wildlife and humans. Three rounds of ambient toxicity tests on six streams and seeps, using the microcrustacean Ceriodaphnia, have identified potential toxicity in three of the sample sites. Further tests are required to identify the toxicant. No rare or endangered animal species have been identified in the WAG 5 area.

  10. Containment testing for occupied and unoccupied laboratory chemical hoods

    Energy Technology Data Exchange (ETDEWEB)

    Greenley, P.L.; DiBerardinis, L.J.; Lorch, F.A.

    1999-07-01

    Containment of hazards in a laboratory chemical hood is based on the principle that air drawn through the face area of the hood is sufficient to overcome the many challenges at or near the opening. Challenges to overcome include, but are not limited to, air velocities near the hood, movement of the researcher, people walking past the hood, location of equipment inside the hood, size of the sash opening, and the shape and configuration of entrance conditions. To overcome these challenges, a sufficient face velocity must be maintained. Determining that proper face velocity must be maintained. Determining that proper face velocity for a given hood should be resolved by the system designer, facility safety officer, and researcher with these and other issues in mind. This research tests for containment at 100 feet per minute (fpm) face velocity on occupied hoods and tests the same hoods for containment at the reduced velocity of 60 fpm when unoccupied. Three laboratory chemical hoods of different sizes with several ash positions are used. The test results show that under ideal conditions in a test laboratory, an unoccupied hood (without a manikin) at 60 fpm contains as good as, if not better than, an occupied hood (with a manikin) at 100 fpm, as measured by the tracer gas tests specified in ANSI/ASHRAE 110-1995, Method of Testing Performance of Laboratory Fume Hoods (ASHRAE 1995). Further testing is needed to determine if this relationship is the same under conditions of actual use, i.e., cluttered hoods and presence of cross-drafts.

  11. Characterization of mudrocks: a practical application of advanced laboratory testing

    Institute of Scientific and Technical Information of China (English)

    Richard J.JARDINE

    2011-01-01

    An integrated approach to geomaterial characterization is advocated that combines geology, in-situ testing, fabric studies, routine index experiments and advanced laboratory testing. It is shown that advanced laboratory testing can explore features such as kinematic yielding and anisotropy in stiffness or shear strength that would otherwise be impossible to quantify. A detailed study performed in London clay at the new Heathrow Terminal 5 site is used to illustrate the arguments made. It is shown that the London clay has strong anisotropy in stiffness, is highly non-linear over the strain range of engineering interest, has markedly anisotropic shear strength characteristics and exhibits a pronounced degree of brittleness. These features can impact significantly on the practical design and analysis of civil engineering works including shallow and deep foundations, tunnels and excavations, and the stability of slopes.

  12. Comparison of Recuperator Alloy Degradation in Laboratory and Engine Testing

    Energy Technology Data Exchange (ETDEWEB)

    Pint, Bruce A [ORNL; More, Karren Leslie [ORNL; Trejo, Rosa M [ORNL; Lara-Curzio, Edgar [ORNL

    2008-01-01

    In order to increase the efficiency of advanced microturbines, durable alloy foils are needed for their recuperators to operate at 650-700 C. Prior work has demonstrated that water vapor in the exhaust gas causes more rapid consumption of Cr from austenitic alloys, leading to a reduction in lifetime for the thin-walled components in this application. New commercial alloy foils are being tested in both laboratory tests in humid air and in the exhaust gas of a modified 60 kW microturbine. Initial results are presented for a commercial batch of 80 {micro}m alloy 120 foil. The Cr consumption rates in laboratory testing were similar to those observed in previous testing. The initial results from the microturbine indicate a faster Cr consumption rate compared to the laboratory test, but longer term results are needed to quantify the difference. These results will help to verify a Cr consumption model for predicting lifetimes in this environment based on classical gas transport theory.

  13. Platform for dynamic tests: preliminary studies, design and construction

    Directory of Open Access Journals (Sweden)

    J. E. Campuzano

    Full Text Available This paper is about the design and construction of a platform for dynamic tests especially with people jumping, walking, etc. Initially it was tried to find out projects already implemented in platforms and dynamic tests and to study the loads produced by movement of people on slabs and the structural response to these loads. The limits established by different standards have been also studied for these dynamic responses, taking into account the ultimate limit state, as well as the structure in service, since the human body is very sensitive to structural vibrations. Parametric studies were performed considering various configurations of slabs (different spans, thicknesses and conditions of support have been done, looking for a configuration that could have natural frequency close to the frequencies of the human loads. The slab should have dimensions compatible with the available physical space, fundamental frequency below 5 Hz and maximum immediate deflection compatible with the indications of the Brazilian standard NBR6118: 2007. Based on these criteria was chosen a rectangular structure consists of a solid reinforced concrete rectangular slab studded in two opposite edges of steel beams with shear connectors type U. The other two edges are free. The steel beams supporting the slab, in turn, are supported on eight metal profiles (two in each corner of the slab that are supported on two to two short columns of steel profile H. Profiles U in steel are welded to four columns, forming a horizontal frame. Numerical analysis of the dynamic test platform have been performed for free and forced vibration, for obtaining the natural frequencies and corresponding vibration modes, considering the self-weight of the structure and the load that simulates people's weight. After obtaining a structural configuration that fulfilled the stipulated requirements, the design of the slab taking into account the recommendations of the Brazilian standard NBR6118: 2007

  14. Identifying the Clinical Laboratory Tests from Unspecified "Other Lab Test" Data for Secondary Use.

    Science.gov (United States)

    Pan, Xuequn; Cimino, James J

    2015-01-01

    Clinical laboratory results are stored in electronic health records (EHRs) as structured data coded with local or standard terms. However, laboratory tests that are performed at outside laboratories are often simply labeled "outside test" or something similar, with the actual test name in a free-text result or comment field. After being aggregated into clinical data repositories, these ambiguous labels impede the retrieval of specific test results. We present a general multi-step solution that can facilitate the identification, standardization, reconciliation, and transformation of such test results. We applied our approach to data in the NIH Biomedical Translational Research Information System (BTRIS) to identify laboratory tests, map comment values to the LOINC codes that will be incorporated into our Research Entities Dictionary (RED), and develop a reference table that can be used in the EHR data extract-transform-load (ETL) process.

  15. Testing hygrometers used in cytogenetics laboratories for metaphase preparation.

    Science.gov (United States)

    Hartley, Thomas; Dun, Karen

    2011-07-01

    This protocol describes procedures for checking small laboratory hygrometers for accuracy at three relative humidity (rh) levels. The work arose out of the need to provide laboratory assessors with documentary evidence that the hygrometer used to monitor humidity in the vicinity of the laboratory where medical cytogenetics testing slides are prepared and dried in the ambient environment is reproducible and sufficiently accurate. The procedure is based upon the physicochemical principle that when water or certain saturated salt solutions are placed into a sealed environment, the humidity will equilibrate to well defined levels. We choose to check our hygrometers at three points: 95%, 75%, and 33% rh, using distilled water, saturated sodium chloride solution, and saturated magnesium chloride solution, respectively. Our results have demonstrated that the procedure is convenient and of sufficient accuracy to be fit for this annual hygrometer validation purpose. The procedure takes 24 hr per relative humidity point checked.

  16. Environmental Survey preliminary report, Nevada Test Site, Mercury, Nevada

    Energy Technology Data Exchange (ETDEWEB)

    1988-04-01

    This report presents the preliminary findings from the first phase of the Environmental Survey of the United States Department of Energy (DOE) Nevada Test Site (NTS), conducted June 22 through July 10, 1987. The Survey is being conducted by a multidisciplinary team of environmental specialists led and managed by the Office of Environment, Safety and Health's Office of Environmental Audit. Individual team members are outside experts being supplied by a private contractor. The objective of the Survey is to identify environmental problems and areas of environmental risk associated with the NTS. The Survey covers all environment media and all areas of environmental regulation. It is being performed in accordance with the DOE Environmental Survey Manual. This phase of the Survey involves the review of existing site environmental data, observations of the operations and activities performed at the NTS, and interviews with site personnel. The Survey team developed a Sampling and Analysis Plan to assist in further assessing certain environmental problems identified during its on-site activities. The Sampling and Analysis Plan is being executed by the Battelle Columbus Division under contract with DOE. When completed, the results will be incorporated into the NTS Environmental Survey Interim Report. The Interim Report will reflect the final determinations of the NTS Survey. 165 refs., 42 figs., 52 tabs.

  17. Preliminary Tests Of The Decris-sc Ion Source

    CERN Document Server

    Efremov, A; Bechterev, V; Bogomolov, S L; Bondarenko, P G; Datskov, V I; Dmitriev, S; Drobin, V; Lebedev, A; Leporis, M; Malinowski, H; Nikiforov, A; Paschenko, S V; Seleznev, V; Shishov, Yu A; Smirnov, Yu; Tsvineva, G; Yakovlev, B; Yazvitsky, N Yu

    2004-01-01

    A new "liquid He-free" superconducting Electron Cyclotron Resonance Ion Source DECRIS-SC, to be used as injector for the IC-100 small cyclotron, has been designed by FLNR and LHE JINR. The main feature is that a compact refrigerator of Gifford-McMahon type is used to cool the solenoid coils. For the reason of very small cooling power at 4.2 K (about 1 W) our efforts were to optimize the magnetic structure and minimize an external heating of the coils. The maximum magnetic field strength is 3 T and 2 T in injection and extraction region respectively. For the radial plasma confinement a hexapole made of NdFeB permanent magnet is used. The source will be capable of ECR plasma heating using different frequencies (14 GHz or 18 GHz). To be able to deliver usable intensities of solids, the design is also allow axial access for evaporation oven and metal samples using the plasma sputtering technique. Very preliminary results of the source test are presented.

  18. Test plan for preliminary study of inorganic contaminant removal from RMA groundwater

    Energy Technology Data Exchange (ETDEWEB)

    Thompson, D.; Terkonda, P.; Weeks, N.

    1978-02-01

    This document consists of a major report on inorganic contaminant removal from ground water. In this plan, WES has been requested by the OPM-CDIR to conduct a literature review and preliminary laboratory treatability studies on various source waters at RMA. Recommendation is that the determination of suitable treatment processes be based on both engineering and economic analysis and that the processes be compatible with the organic contaminant treatment processes under study (activated carbon adsorption and ultraviolet/ozone oxidation). The amendment to the test plan presents the inorganic treatment processes found from the literature to be applicable to the inorganic contaminants in RMA ground water and outlines the bench scale study to be conducted at WES using the potential processes. The rest of the document is correspondence and reports on various water treatability.

  19. Oral fluid for workplace drug testing: laboratory implementation.

    Science.gov (United States)

    Moore, Christine

    2012-02-01

    As oral fluid increases in popularity for workplace testing, due to its easy and observed collection, the ability to adapt existing laboratory instrumentation without further capital investment will allow more facilities to test oral fluid. The European Workplace Drug Testing Society (EWDTS) guidelines for oral fluid testing outline the maximum cut-off concentrations acceptable under the workplace drug testing programme. The recommended cut-off values may be subject to change as advances in technology or other considerations warrant identification of these substances at different concentrations; however, the instrumentation currently exists for routine screening using immunoassay and confirmation by gas chromatography-mass spectrometry (GC-MS) or liquid chromatography with tandem mass spectral detection (LC-MS/MS) so laboratories can easily implement oral fluid analysis in their current systems. Immunoassays for the detection of the drug classes at recommended levels have been developed using various collection devices and different formats: liquid reagent chemistries and enzyme-linked immunosorbent assay (ELISA) platforms. Immunoassays provide faster turnaround than mass spectral methods particularly when the number of specimens increases. Since the guidelines state that positive immunoassay results should not be reported without confirmation, fully validated methods using LC-MS/MS and/or GC-MS for all drugs are also widely available. All proposed concentrations are easily achievable using MS instruments currently in testing laboratories; however, the likelihood of a low number of positive specimens in workplace populations allows the test facility to screen specimens in a cost-effective manner using immunoassay, while ensuring scientific credibility and defensibility by confirming the positive results with a second test. Copyright © 2011 John Wiley & Sons, Ltd.

  20. Preliminary volcanic hazards evaluation for Los Alamos National Laboratory Facilities and Operations : current state of knowledge and proposed path forward

    Energy Technology Data Exchange (ETDEWEB)

    Keating, Gordon N.; Schultz-Fellenz, Emily S.; Miller, Elizabeth D.

    2010-09-01

    The integration of available information on the volcanic history of the region surrounding Los Alamos National Laboratory indicates that the Laboratory is at risk from volcanic hazards. Volcanism in the vicinity of the Laboratory is unlikely within the lifetime of the facility (ca. 50–100 years) but cannot be ruled out. This evaluation provides a preliminary estimate of recurrence rates for volcanic activity. If further assessment of the hazard is deemed beneficial to reduce risk uncertainty, the next step would be to convene a formal probabilistic volcanic hazards assessment.

  1. 49 CFR 40.81 - What laboratories may be used for DOT drug testing?

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 1 2010-10-01 2010-10-01 false What laboratories may be used for DOT drug testing... TRANSPORTATION WORKPLACE DRUG AND ALCOHOL TESTING PROGRAMS Drug Testing Laboratories § 40.81 What laboratories may be used for DOT drug testing? (a) As a drug testing laboratory located in the U.S., you are...

  2. Geomechanical properties of Topopah Spring Tuff at the 0.5-m scale: preliminary results of compression tests at elevated temperature

    Energy Technology Data Exchange (ETDEWEB)

    Blair, S. C., LLNL

    1997-08-25

    This report presents preliminary results of laboratory testing of a small block sample of Topopah Spring Tuff. This is the first in a series of tests on small block samples. The purpose of these tests is to investigate the thermal-mechanical, thermal-hydrological, and thermal-chemical response of the rock to conditions similar to the near-field environment (NFE) of a potential nuclear waste repository. This report presents preliminary results of deformation and elastic- wave velocity measurements on a 0.5-m scale block of Topopah Spring tuff tested in uniaxial compression and at temperatures to 85{degrees}C.

  3. CONTROL TESTING OF THE UK NATIONAL NUCLEAR LABORATORY'S RADBALL TECHNOLOGY AT SAVANNAH RIVER NATIONAL LABORATORY

    Energy Technology Data Exchange (ETDEWEB)

    Farfan, E.

    2009-11-23

    The UK National Nuclear Laboratory (NNL) has developed a remote, non-electrical, radiation-mapping device known as RadBall (patent pending), which offers a means to locate and quantify radiation hazards and sources within contaminated areas of the nuclear industry. To date, the RadBall has been deployed in a number of technology trials in nuclear waste reprocessing plants at Sellafield in the UK. The trials have demonstrated the successful ability of the RadBall technology to be deployed and retrieved from active areas. The positive results from these initial deployment trials and the anticipated future potential of RadBall have led to the NNL partnering with the Savannah River National Laboratory (SRNL) to further underpin and strengthen the technical performance of the technology. RadBall consists of a colander-like outer shell that houses a radiation-sensitive polymer sphere. It has no power requirements and can be positioned in tight or hard-to reach places. The outer shell works to collimate radiation sources and those areas of the polymer sphere that are exposed react, becoming increasingly less transparent, in proportion to the absorbed dose. The polymer sphere is imaged in an optical-CT scanner which produces a high resolution 3D map of optical attenuation coefficients. Subsequent analysis of the optical attenuation maps provides information on the spatial distribution and strength of the sources in a given area forming a 3D characterization of the area of interest. This study completed at SRNL addresses key aspects of the testing of the RadBall technology. The first set of tests was performed at Savannah River Nuclear Solutions Health Physics Instrument Calibration Laboratory (HPICL) using various gamma-ray sources and an x-ray machine with known radiological characteristics. The objective of these preliminary tests was to identify the optimal dose and collimator thickness. The second set of tests involved a highly contaminated hot cell. The objective of

  4. Inflammatory bowel diseases: from pathogenesis to laboratory testing.

    Science.gov (United States)

    Basso, Daniela; Zambon, Carlo-Federico; Plebani, Mario

    2014-04-01

    Inflammatory bowel diseases (IBDs), which comprise the two major clinical subtypes, Crohn's disease and ulcerative colitis, incur high morbidity and potential mortality. The present study reviews data on the pathogenesis and diagnosis of IBDs. The pathogenesis depends on complex interactions between susceptibility genes, environmental factors, and innate and adaptive immunity, the understanding of which is crucial to discovering novel laboratory biomarkers. Traditional laboratory tests for the diagnosis, prognosis and assessment of disease activity of IBDs are reported on, and the biochemical properties, pre-analytical and analytical aspects and clinical utility of the fecal markers lactoferrin and calprotectin are described. DNA testing and established (ASCA and pANCA) and emerging (ACCA, ALCA, AMCA, OmpC) serum markers are described; a further aspect to be addressed is the clinical use of pharmacogenetics for the treatment of IBDs.

  5. Weld Tests Conducted by the Idaho National Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Larry Zirker; Lance Lauerhass; James Dowalo

    2007-02-01

    During the fiscal year of 2006, the Idaho National Laboratory (INL) performed many tests and work relating to the Mobile Melt-Dilute (MMD) Project components. Tests performed on the Staubli quick disconnect fittings showed promising results, but more tests were needed validate the fittings. Changes were made to the shield plug design—reduced the closure groove weld depth between the top of the canister and the top plate of the shielding plug from 0.5-in to 0.375-in deep. Other changes include a cap to cover the fitting, lifting pintle and welding code citations on the prints. Tests conducted showed stainless steel tubing, with 0.25-in, 0.375-in, and 0.5-in diameters, all with 0.035-in wall thickness, could be pinch seal welded using commercially available resistance welding equipment. Subsequent testing showed that these welds could be real-time inspected with ultrasonic inspection methods.

  6. Final definition and preliminary design study for the initial atmospheric cloud physics laboratory, a Spacelab mission payload

    Science.gov (United States)

    1976-01-01

    The following areas related to the final definition and preliminary design study of the initial atmospheric cloud physics laboratory (ACPL) were covered: (1) proposal organization, personnel, schedule, and project management, (2) proposed configurations, (3) study objectives, (4) ACPL experiment program listing and description, (5) mission/flight flexibility and modularity/commonality, (6) study plan, and (7) description of following tasks: requirement analysis and definition task flow, systems analysis and trade studies, subsystem analysis and trade studies, specifications and interface control documents, preliminary design task flow, work breakdown structure, programmatic analysis and planning, and project costs. Finally, an overview of the scientific requirements was presented.

  7. LABORATORY TESTING OF LEICA AT401 LASER TRACKER

    Directory of Open Access Journals (Sweden)

    Filip Dvořáček

    2016-04-01

    Full Text Available This paper describes laboratory tests on a Leica AT401laser tracker. As the newer Leica AT402 model also uses the same firmware package, most of the results should also be valid for this device. First, we present the instrument’s firmware errors and the software used for testing. The ASME B89.4.19-2006 standard for testing laser trackers is briefly presented. The warm-up effect of the instrument is inspected with respect to both angle measurement and distance measurement. The absolute distance meter (ADM is compared with a laboratory interferometer on a 30-meter long rail and also on a bench with automated movement of the carriage of the reflector. A time series of measurements for determining the additive constant is evaluated. A simple test of the stability of the distance measurement in field conditions is introduced. Most of the tests were carried out at the Research Institute of Geodesy, Topography and Cartography (RIGTC and at the Faculty of Civil Engineering (FCE of the Czech Technical University in Prague (CTU.

  8. Mobile Energy Laboratory energy-efficiency testing programs

    Energy Technology Data Exchange (ETDEWEB)

    Parker, G.B.; Currie, J.W.

    1991-09-01

    This report summarizes energy-efficiency testing activities applying the Mobile Energy Laboratory (MEL) testing capabilities during the first and second quarters of fiscal year (FY) 1991. The MELs, developed by the US Department of Energy (DOE) Federal Energy Management Program (FEMP), are administered by Pacific Northwest Laboratory (PNL) and the Naval Energy and Environmental Support Activity (NEESA) for energy testing and energy conservation program support functions at federal facilities. The using agencies principally fund MEL applications, while DOE/FEMP funds program administration and capability enhancement activities. This report fulfills the requirements established in Section 8 of the MEL Use Plan (PNL-6861) for semiannual reporting on energy-efficiency testing activities using the MEL capabilities. The MEL Use Committee, formally established in 1989, developed the MEL Use Plan and meets semiannually to establish priorities for energy-efficient testing applications using the MEL capabilities. The MEL Use Committee is composed of one representative each of the US Department of Energy, US Army, US Air Force, US Navy, and other federal agencies.

  9. The LINC-NIRVANA fringe and flexure tracker: laboratory tests

    Science.gov (United States)

    Tremou, Evangelia; Eckart, Andreas; Horrobin, Matthew; Lindhorst, Bettina; Moser, Lydia; Rost, Steffen; Smajic, Semir; Straubmeier, Christian; Wank, Imke; Zuther, Jens; Bertram, Thomas

    2010-07-01

    LINC-NIRVANA is the NIR homothetic imaging camera for the Large Binocular Telescope (LBT). In close cooperation with the Adaptive Optics systems of LINC-NIRVANA the Fringe and Flexure Tracking System (FFTS) is a fundamental component to ensure a complete and time-stable wavefront correction at the position of the science detector in order to allow for long integration times at interferometric angular resolutions. In this contribution, we present the design and the realization of the ongoing FFTS laboratory tests, taking into account the system requirements. We have to sample the large Field of View and to follow the reference source during science observations to an accuracy of less than 2 microns. In particular, important tests such as cooling tests of cryogenic components and tip - tilt test (the repeatability and the precision under the different inclinations) are presented. The system parameters such as internal flexure and precision are discussed.

  10. Evidence-based laboratory medicine - a guide for critical evaluation of in vitro laboratory testing.

    Science.gov (United States)

    Christenson, Robert H

    2007-03-01

    Evidence-based laboratory medicine (EBLM) is an essential part of modern laboratory medicine practice. This review presents a guide for better understanding and implementing the EBLM process. The process of EBLM begins with development of a clinically relevant question. Tools for assisting in question formulation include the Patient Intervention Comparator and Outcome (PICO) or Case Assay Predicate and Outcome (CAPO) strategies. Locating evidence that addresses the question is performed using resources available on the internet. Systematic reviews that have objectively collated evidence addressing the question can be particularly useful. The evidence collected must be critically appraised using checklists developed for this purpose. Diagnostic performance of tests is frequently stated in terms of sensitivity, specificity, negative and positive predictive values, and the diagnostic odds ratio. Evaluating 95% confidence limits is important for interpretation. Likelihood ratios for tests in disease states are also important for converting pre-test probabilities to post-test probabilities using Bayes Theorem. Tools such as Receiver Operator Characteristic curves and Fagan's diagram are important analytical and visual aids. Laboratorians must give thoughtful consideration into conveying information to clinicians in a useful format. Evidence-based guidelines and collaboration with clinicians are important for development of local care paths. Auditing the effectiveness of implemented care paths is an important part of quality management. In conclusion, effective use of EBLM can benefit patients by helping laboratorians provide the best-available information in the clinically relevant time frame. Presenting the information appropriately maximizes clinical application of the best evidence.

  11. Application of flexible scope in large testing laboratories

    Directory of Open Access Journals (Sweden)

    Carina Di Candia

    2011-04-01

    Full Text Available According as the international definition of Flexible Scope, a laboratory must demonstrate face with the accreditation body that it has the knowledge, experience and competence to work within the full range of its flexible scope, as well as possessing suitable laboratory environments and equipment. The laboratory must also demonstrate that it has a management system in place that can control its proposed approach while continuing to comply with the requirements of ISO 17025:2005. In case of UKAS (Unites Kingdom Accreditation Service, prior to offering accreditation for flexible scope they must have a high degree of confidence that the staff are technically competent and that the management system controlling certain key processes as development, review, validation and authorization.LATU apply these requirements since 2004 as "Unified Tests". Until this date, LATU was doing the same type of tests in different materials departments using different equipment, personal, and testing quality control. In order to that were defined cross disciplinary groups to analyze this topic approaching in personal competence and quality control tests improvement, and resource's decrease. For example, LATU has the Unified Test Tensile Strength accredited by UKAS in: corrugated and solid fiberboard, paper board, linerboard, cork plugs, plastic bags, plastic sheeting, paper, woven fabrics, plastic woven bags and woven plastic. As a result of the Unified Tests was generated a general unified manage procedure with unified criteria's, responsibilities and actions. Was written a unique testing procedure not only with the actual flexible scope and the flexibilities limits but also the compliance requirements of ISO 17025 and the accreditations body methodology. We could decrease the amount of documentation to control. Was defined the methodology and implemented periodicaly internal inter comparisons between departments in order to valid the unified tests and has a unique

  12. The Role of Laboratory Tests in Crohn’s Disease

    Science.gov (United States)

    Cappello, Maria; Morreale, Gaetano Cristian

    2016-01-01

    In the past, laboratory tests were considered of limited value in Crohn’s disease (CD). In the era of biologics, laboratory tests have become essential to evaluate the inflammatory burden of the disease (C-reactive protein, fecal calprotectin) since symptoms-based scores are subjective, to predict the response to pharmacological options and the risk of relapse, to discriminate CD from ulcerative colitis, to select candidates to anti-tumor necrosis factors [screening tests looking for hepatitis B virus and hepatitis C virus status and latent tuberculosis], to assess the risk of adverse events (testing for thiopurine metabolites and thiopurine-methyltransferase activity), and to personalize and optimize therapy (therapeutic drug monitoring). Pharmacogenetics, though presently confined to the assessment of thiopurineme methyltransferase polymorphisms and hematological toxicity associated with thiopurine treatment, is a promising field that will contribute to a better understanding of the molecular mechanisms of the variability in response to the drugs used in CD with the attempt to expand personalized care and precision medicine strategies. PMID:27656094

  13. Laboratory testing for cobalamin deficiency in megaloblastic anemia.

    Science.gov (United States)

    Oberley, Matthew J; Yang, David T

    2013-06-01

    Cobalamin (vitamin B12) deficiency is a common cause of megaloblastic anemia in Western populations. Laboratory evaluation of megaloblastic anemia frequently includes the assessment of patient cobalamin and folate status. Current total serum cobalamin measurements are performed in the clinical laboratory with competitive binding luminescence assays, whose results may not always accurately reflect actual cobalamin stores. Surrogate markers of cobalamin deficiency such as methylmalonic acid and homocysteine have been utilized to improve diagnostic accuracy; however, the specificity of these tests by themselves is rather low. Measurement of the biologically active fraction of cobalamin, holotranscobalamin, has been proposed as a replacement for current total cobalamin assays. Although holotranscobalamin measurements appear to have slighter better sensitivity, the specificity of this assay remains to be determined. The relative merits and demerits of commonly available methods to assess cobalamin deficiency in patients with suspected megaloblastic anemia are discussed. Copyright © 2013 Wiley Periodicals, Inc.

  14. CERTS Microgrid Laboratory Test Bed - PIER Final Project Report

    Energy Technology Data Exchange (ETDEWEB)

    Eto, Joseph H.; Eto, Joseph H.; Lasseter, Robert; Schenkman, Ben; Klapp, Dave; Linton, Ed; Hurtado, Hector; Roy, Jean; Lewis, Nancy Jo; Stevens, John; Volkommer, Harry

    2008-07-25

    The objective of the CERTS Microgrid Laboratory Test Bed project was to enhance the ease of integrating small energy sources into a microgrid. The project accomplished this objective by developing and demonstrating three advanced techniques, collectively referred to as the CERTS Microgrid concept, that significantly reduce the level of custom field engineering needed to operate microgrids consisting of small generating sources. The techniques comprising the CERTS Microgrid concept are: 1) a method for effecting automatic and seamless transitions between grid-connected and islanded modes of operation; 2) an approach to electrical protection within the microgrid that does not depend on high fault currents; and 3) a method for microgrid control that achieves voltage and frequency stability under islanded conditions without requiring high-speed communications. The techniques were demonstrated at a full-scale test bed built near Columbus, Ohio and operated by American Electric Power. The testing fully confirmed earlier research that had been conducted initially through analytical simulations, then through laboratory emulations, and finally through factory acceptance testing of individual microgrid components. The islanding and resychronization method met all Institute of Electrical and Electronics Engineers 1547 and power quality requirements. The electrical protections system was able to distinguish between normal and faulted operation. The controls were found to be robust and under all conditions, including difficult motor starts. The results from these test are expected to lead to additional testing of enhancements to the basic techniques at the test bed to improve the business case for microgrid technologies, as well to field demonstrations involving microgrids that involve one or mroe of the CERTS Microgrid concepts.

  15. A spatially-dynamic preliminary risk assessment of the bald eagle at the Los Alamos National Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Gonzales, G.J.; Gallegos, A.F.; Foxx, T.S.; Fresquez, P.R.; Mullen, M.A.; Pratt, L.E.; Gomez, P.E.

    1998-04-01

    The Endangered Species Act of 1973 and the Record of Decision on the Dual Axis Radiographic Hydrodynamic Test Facility at the Los Alamos National Laboratory (LANL) require that the Department of Energy protect the bald eagle (Haliaeetus leucocephalus), a state and federally listed species, from stressors such as contaminants. A preliminary risk assessment of the bald eagle was performed using a custom FORTRAN code, ECORSK5, and the geographical information system. Estimated exposure doses to the eagle for radionuclide, inorganic metal, and organic contaminants were derived for varying ratios of aquatic vs. terrestrial simulated diet and compared against toxicity reference values to generate hazard indices (His). HI results indicate that no appreciable impact to the bald eagle is expected from contaminants at LANL from soil ingestion and food consumption pathways. This includes a measure of cumulative effects from multiple contaminants that assumes linear additive toxicity. Improving model realism by weighting simulated eagle foraging based on distance from potential roost sites increased the HI by 76%, but still to inconsequential levels. Information on risk by specific geographical location was generated, which can be used to manage contaminated areas, eagle habitat, facility siting, and/or facility operations in order to maintain risk from contaminants at low levels.

  16. Black holes a laboratory for testing strong gravity

    CERN Document Server

    Bambi, Cosimo

    2017-01-01

    This textbook introduces the current astrophysical observations of black holes, and discusses the leading techniques to study the strong gravity region around these objects with electromagnetic radiation. More importantly, it provides the basic tools for writing an astrophysical code and testing the Kerr paradigm. Astrophysical black holes are an ideal laboratory for testing strong gravity. According to general relativity, the spacetime geometry around these objects should be well described by the Kerr solution. The electromagnetic radiation emitted by the gas in the inner part of the accretion disk can probe the metric of the strong gravity region and test the Kerr black hole hypothesis. With exercises and examples in each chapter, as well as calculations and analytical details in the appendix, the book is especially useful to the beginners or graduate students who are familiar with general relativity while they do not have any background in astronomy or astrophysics.

  17. Accelerated stress testing of thin film solar cells: Development of test methods and preliminary results

    Science.gov (United States)

    Lathrop, J. W.

    1985-01-01

    If thin film cells are to be considered a viable option for terrestrial power generation their reliability attributes will need to be explored and confidence in their stability obtained through accelerated testing. Development of a thin film accelerated test program will be more difficult than was the case for crystalline cells because of the monolithic construction nature of the cells. Specially constructed test samples will need to be fabricated, requiring committment to the concept of accelerated testing by the manufacturers. A new test schedule appropriate to thin film cells will need to be developed which will be different from that used in connection with crystalline cells. Preliminary work has been started to seek thin film schedule variations to two of the simplest tests: unbiased temperature and unbiased temperature humidity. Still to be examined are tests which involve the passage of current during temperature and/or humidity stress, either by biasing in the forward (or reverse) directions or by the application of light during stress. Investigation of these current (voltage) accelerated tests will involve development of methods of reliably contacting the thin conductive films during stress.

  18. Digital Audio Radio Broadcast Systems Laboratory Testing Nearly Complete

    Science.gov (United States)

    2005-01-01

    Radio history continues to be made at the NASA Lewis Research Center with the completion of phase one of the digital audio radio (DAR) testing conducted by the Consumer Electronics Group of the Electronic Industries Association. This satellite, satellite/terrestrial, and terrestrial digital technology will open up new audio broadcasting opportunities both domestically and worldwide. It will significantly improve the current quality of amplitude-modulated/frequency-modulated (AM/FM) radio with a new digitally modulated radio signal and will introduce true compact-disc-quality (CD-quality) sound for the first time. Lewis is hosting the laboratory testing of seven proposed digital audio radio systems and modes. Two of the proposed systems operate in two modes each, making a total of nine systems being tested. The nine systems are divided into the following types of transmission: in-band on-channel (IBOC), in-band adjacent-channel (IBAC), and new bands. The laboratory testing was conducted by the Consumer Electronics Group of the Electronic Industries Association. Subjective assessments of the audio recordings for each of the nine systems was conducted by the Communications Research Center in Ottawa, Canada, under contract to the Electronic Industries Association. The Communications Research Center has the only CCIR-qualified (Consultative Committee for International Radio) audio testing facility in North America. The main goals of the U.S. testing process are to (1) provide technical data to the Federal Communication Commission (FCC) so that it can establish a standard for digital audio receivers and transmitters and (2) provide the receiver and transmitter industries with the proper standards upon which to build their equipment. In addition, the data will be forwarded to the International Telecommunications Union to help in the establishment of international standards for digital audio receivers and transmitters, thus allowing U.S. manufacturers to compete in the

  19. Antifungal susceptibility testing method for resource constrained laboratories

    Directory of Open Access Journals (Sweden)

    Khan S

    2006-01-01

    Full Text Available Purpose: In resource-constrained laboratories of developing countries determination of antifungal susceptibility testing by NCCLS/CLSI method is not always feasible. We describe herein a simple yet comparable method for antifungal susceptibility testing. Methods: Reference MICs of 72 fungal isolates including two quality control strains were determined by NCCLS/CLSI methods against fluconazole, itraconazole, voriconazole, amphotericin B and cancidas. Dermatophytes were also tested against terbinafine. Subsequently, on selection of optimum conditions, MIC was determined for all the fungal isolates by semisolid antifungal agar susceptibility method in Brain heart infusion broth supplemented with 0.5% agar (BHIA without oil overlay and results were compared with those obtained by reference NCCLS/CLSI methods. Results: Comparable results were obtained by NCCLS/CLSI and semisolid agar susceptibility (SAAS methods against quality control strains. MICs for 72 isolates did not differ by more than one dilution for all drugs by SAAS. Conclusions: SAAS using BHIA without oil overlay provides a simple and reproducible method for obtaining MICs against yeast, filamentous fungi and dermatophytes in resource-constrained laboratories.

  20. A Preliminary Clinical Laboratory Investigation of Endemic Spiking Mortality Syndrome of Broiler Chickens in Nepal

    Directory of Open Access Journals (Sweden)

    Tika Ram Neupane

    Full Text Available During the period of March-April-May 2008 first time a sudden and unexpected jump in mortality in Broiler of 8 to 16 days of age was reported from broiler farms from Chitwan and Kathmandu valley in Nepal.Affected birds become recumbent, depressed and often go into a star-gazing spasm. Those signs included, huddling of the birds, trembling, blindness, loud chirping, litter eating, ataxia, comatose, birds dead with breast down and feet and legs straight out behind birds. Death within two to six hours after the onset of the symptoms Postmortem Lesions found with this syndrome include hemorrhages in the liver with necrosis of liver cells, regressed thymus, regression of the bursa of Fabricius, dehydration with the accumulation of kidney urates, fluid in the crop, fluid in the lower gut and watery contents of the ceca.Yellow elastic shanks swollen joints. Molted appearance of brain. . The mortality lasted for three to five days, after which, the mortality patterns return to a relatively normal level. When treated with liquid toxin binders like toxol,toxolivum,livertonic like hepatocare,naturaliv, immunomodulaters like immunocare,promin,pentasol and antibiotics there was check in mortality but the body weight recovery was not satisfactory only half as in comparison of in other illness. During this period laboratory culture of total 298 tissue specimen from dead bird was conducted which revealed growth of fungus spp like Aspergillus and Penicillium in 182 specimen while mixed E.coli and Staphylococcus were recovered in 68 specimen 24 specimen revealed the growth of Salmonella spp of bacteria and 24 samples were turn out to be negative while the attempt to isolate the Avian encephalomyelitis virus as it might be the cause suspected also turnout negative. On the basis of all laboratory findings and response to the treatment attempted finding of this preliminary investigation work is suggestive that the above syndrome indicates that mycosis emerging as

  1. Preliminary siting activities for new waste handling facilities at the Idaho National Engineering Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Taylor, D.D.; Hoskinson, R.L.; Kingsford, C.O.; Ball, L.W.

    1994-09-01

    The Idaho Waste Processing Facility, the Mixed and Low-Level Waste Treatment Facility, and the Mixed and Low-Level Waste Disposal Facility are new waste treatment, storage, and disposal facilities that have been proposed at the Idaho National Engineering Laboratory (INEL). A prime consideration in planning for such facilities is the selection of a site. Since spring of 1992, waste management personnel at the INEL have been involved in activities directed to this end. These activities have resulted in the (a) identification of generic siting criteria, considered applicable to either treatment or disposal facilities for the purpose of preliminary site evaluations and comparisons, (b) selection of six candidate locations for siting,and (c) site-specific characterization of candidate sites relative to selected siting criteria. This report describes the information gathered in the above three categories for the six candidate sites. However, a single, preferred site has not yet been identified. Such a determination requires an overall, composite ranking of the candidate sites, which accounts for the fact that the sites under consideration have different advantages and disadvantages, that no single site is superior to all the others in all the siting criteria, and that the criteria should be assigned different weighing factors depending on whether a site is to host a treatment or a disposal facility. Stakeholder input should now be solicited to help guide the final selection. This input will include (a) siting issues not already identified in the siting, work to date, and (b) relative importances of the individual siting criteria. Final site selection will not be completed until stakeholder input (from the State of Idaho, regulatory agencies, the public, etc.) in the above areas has been obtained and a strategy has been developed to make a composite ranking of all candidate sites that accounts for all the siting criteria.

  2. Retrofitting Combined Space and Water Heating Systems. Laboratory Tests

    Energy Technology Data Exchange (ETDEWEB)

    Schoenbauer, B. [NorthernStar Building America Partnership, St. Paul, MN (United States); Bohac, D. [NorthernStar Building America Partnership, St. Paul, MN (United States); Huelman, P. [NorthernStar Building America Partnership, St. Paul, MN (United States); Olsen, R. [NorthernStar Building America Partnership, St. Paul, MN (United States); Hewett, M. [NorthernStar Building America Partnership, St. Paul, MN (United States)

    2012-10-01

    Better insulated and tighter homes can often use a single heating plant for both space and domestic water heating. These systems, called dual integrated appliances (DIA) or combination systems, can operate at high efficiency and eliminate combustion safety issues associated by using a condensing, sealed combustion heating plant. Funds were received to install 400 DIAs in Minnesota low-income homes. The NorthernSTAR DIA laboratory was created to identify proper system components, designs, operating parameters, and installation procedures to assure high efficiency of field installed systems. Tests verified that heating loads up to 57,000 Btu/hr can be achieved with acceptable return water temperatures and supply air temperatures.

  3. Retrofitting Combined Space and Water Heating Systems: Laboratory Tests

    Energy Technology Data Exchange (ETDEWEB)

    Schoenbauer, B.; Bohac, D.; Huelman, P.; Olson, R.; Hewitt, M.

    2012-10-01

    Better insulated and tighter homes can often use a single heating plant for both space and domestic water heating. These systems, called dual integrated appliances (DIA) or combination systems, can operate at high efficiency and eliminate combustion safety issues associated by using a condensing, sealed combustion heating plant. Funds were received to install 400 DIAs in Minnesota low-income homes. The NorthernSTAR DIA laboratory was created to identify proper system components, designs, operating parameters, and installation procedures to assure high efficiency of field installed systems. Tests verified that heating loads up to 57,000 Btu/hr can be achieved with acceptable return water temperatures and supply air temperatures.

  4. Laboratory tests for disorders of complement and complement regulatory proteins.

    Science.gov (United States)

    Shih, Angela R; Murali, Mandakolathur R

    2015-12-01

    The complement pathway is a cascade of proteases that is involved in immune surveillance and innate immunity, as well as adaptive immunity. Dysfunction of the complement cascade may be mediated by aberrations in the pathways of activation, complement regulatory proteins, or complement deficiencies, and has been linked to a number of hematologic disorders, including paroxysmal noctural hemoglobinuria (PNH), hereditary angioedema (HAE), and atypical hemolytic-uremic syndrome (aHUS). Here, current laboratory tests for disorders of the complement pathway are reviewed, and their utility and limitations in hematologic disorders and systemic diseases are discussed. Current therapeutic advances targeting the complement pathway in treatment of complement-mediated hematologic disorders are also reviewed.

  5. Prototype dish testing and analysis at Sandia National Laboratories

    Science.gov (United States)

    Grossman, J. W.; Houser, R. M.; Erdman, W. W.

    1991-12-01

    During the past year, Sandia National Laboratories performed on-sun testing of several dish concentrator concepts. These tests were undertaken at the National Solar Thermal Test Facility (NSTTF). Two of the tests were performed in support of the DOE Concentrator Receiver Development Program. The first was on-sun testing of the single-element stretched-membrane dish; this 7-meter diameter dish uses a single preformed metal membrane with an aluminized polyester optical surface and shows potential for future dish-Stirling systems. The next involved two prototype facets from the Faceted Stretched-Membrane Dish Program. These facets, representing competitive design concepts, are closest to commercialization. Five 1-meter triangular facets were tested on-sun as part of the development program for a solar dynamic system on Space Station Freedom. While unique in character, all the tests utilized the Beam Characterization System (BCS) as the main measurement tool and all were analyzed using the Sandia-developed CIRCE2 computer code. The BCS is used to capture and digitize an image of the reflected concentrator beam that is incident on a target surface. The CIRCE2 program provides a computational tool, which when given the geometry of the concentrator and target as well as other design parameters will predict the flux distribution of the reflected beam. One of these parameters, slope error, is the variable that has a major effect in determining the quality of the reflected beam. The methodology used to combine these two tools to predict uniform slope errors for the dishes is discussed in this document. As the Concentrator Development Programs continue, Sandia will test and evaluate two prototype dish systems. The first, the faceted stretched-membrane dish, is expected to be tested in 1992, followed by the full-scale single-element stretched-membrane dish in 1993. These tests will use the tools and methodology discussed in this document.

  6. Diagnostic criteria and laboratory tests for disseminated intravascular coagulation.

    Science.gov (United States)

    Wada, Hideo; Matsumoto, Takeshi; Hatada, Tuyoshi

    2012-12-01

    Three diagnostic criteria for disseminated intravascular coagulation (DIC) have been established by the Japanese Ministry of Health, Labor and Welfare, the International Society on Thrombosis and Hemostasis (ISTH) and the Japanese Association for Acute Medicine. The diagnostic criteria involving global coagulation tests, such as the Japanese Ministry of Health, Labor and Welfare criteria and the ISTH overt diagnostic criteria, are first-generation DIC diagnostic criteria, those involving global coagulation tests and changes in these tests such as the Japanese Association for Acute Medicine criteria, are second-generation DIC diagnostic criteria, and those including non-overt DIC diagnostic criteria involving global coagulation tests, changes in these tests and hemostatic molecular markers will be the future (third-generation) DIC diagnostic criteria. There are no significant differences in the three diagnostic criteria with respect to predicting poor outcomes. Therefore, the third generation of diagnostic criteria including hemostatic molecular markers is expected to be established. Standardization and the determination of adequate cutoff values should be required for each laboratory test.

  7. Laboratory Testing of Waste Isolation Pilot Plant Surrogate Waste Materials

    Science.gov (United States)

    Broome, S.; Bronowski, D.; Pfeifle, T.; Herrick, C. G.

    2011-12-01

    The Waste Isolation Pilot Plant (WIPP) is a U.S. Department of Energy geological repository for the permanent disposal of defense-related transuranic (TRU) waste. The waste is emplaced in rooms excavated in the bedded Salado salt formation at a depth of 655 m below the ground surface. After emplacement of the waste, the repository will be sealed and decommissioned. WIPP Performance Assessment modeling of the underground material response requires a full and accurate understanding of coupled mechanical, hydrological, and geochemical processes and how they evolve with time. This study was part of a broader test program focused on room closure, specifically the compaction behavior of waste and the constitutive relations to model this behavior. The goal of this study was to develop an improved waste constitutive model. The model parameters are developed based on a well designed set of test data. The constitutive model will then be used to realistically model evolution of the underground and to better understand the impacts on repository performance. The present study results are focused on laboratory testing of surrogate waste materials. The surrogate wastes correspond to a conservative estimate of the degraded containers and TRU waste materials after the 10,000 year regulatory period. Testing consists of hydrostatic, uniaxial, and triaxial tests performed on surrogate waste recipes that were previously developed by Hansen et al. (1997). These recipes can be divided into materials that simulate 50% and 100% degraded waste by weight. The percent degradation indicates the anticipated amount of iron corrosion, as well as the decomposition of cellulosics, plastics, and rubbers. Axial, lateral, and volumetric strain and axial and lateral stress measurements were made. Two unique testing techniques were developed during the course of the experimental program. The first involves the use of dilatometry to measure sample volumetric strain under a hydrostatic condition. Bulk

  8. Battery Test Facility- Electrochemical Analysis and Diagnostics Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — The Electrochemical Analysis and Diagnostics Laboratory (EADL) provides battery developers with reliable, independent, and unbiased performance evaluations of their...

  9. Laboratory and test beam results from a large-area silicon drift detector

    CERN Document Server

    Bonvicini, V; Giubellino, P; Gregorio, A; Idzik, M; Kolojvari, A A; Montaño-Zetina, L M; Nouais, D; Petta, C; Rashevsky, A; Randazzo, N; Reito, S; Tosello, F; Vacchi, A; Vinogradov, L I; Zampa, N

    2000-01-01

    A very large-area (6.75*8 cm/sup 2/) silicon drift detector with integrated high-voltage divider has been designed, produced and fully characterised in the laboratory by means of ad hoc designed MOS injection electrodes. The detector is of the "butterfly" type, the sensitive area being subdivided into two regions with a maximum drift length of 3.3 cm. The device was also tested in a pion beam (at the CERN PS) tagged by means of a microstrip detector telescope. Bipolar VLSI front-end cells featuring a noise of 250 e/sup -/ RMS at 0 pF with a slope of 40 e/sup -//pF have been used to read out the signals. The detector showed an excellent stability and featured the expected characteristics. Some preliminary results will be presented. (12 refs).

  10. Results from laboratory and field testing of nitrate measuring spectrophotometers

    Science.gov (United States)

    Snazelle, Teri T.

    2015-01-01

    Five ultraviolet (UV) spectrophotometer nitrate analyzers were evaluated by the U.S. Geological Survey (USGS) Hydrologic Instrumentation Facility (HIF) during a two-phase evaluation. In Phase I, the TriOS ProPs (10-millimeter (mm) path length), Hach NITRATAX plus sc (5-mm path length), Satlantic Submersible UV Nitrate Analyzer (SUNA, 10-mm path length), and S::CAN Spectro::lyser (5-mm path length) were evaluated in the HIF Water-Quality Servicing Laboratory to determine the validity of the manufacturer's technical specifications for accuracy, limit of linearity (LOL), drift, and range of operating temperature. Accuracy specifications were met in the TriOS, Hach, and SUNA. The stock calibration of the S::CAN required two offset adjustments before the analyzer met the manufacturer's accuracy specification. Instrument drift was observed only in the S::CAN and was the result of leaching from the optical path insert seals. All tested models, except for the Hach, met their specified LOL in the laboratory testing. The Hach's range was found to be approximately 18 milligrams nitrogen per liter (mg-N/L) and not the manufacturer-specified 25 mg-N/L. Measurements by all of the tested analyzers showed signs of hysteresis in the operating temperature tests. Only the SUNA measurements demonstrated excessive noise and instability in temperatures above 20 degrees Celsius (°C). The SUNA analyzer was returned to the manufacturer at the completion of the Phase II field deployment evaluation for repair and recalibration, and the performance of the sensor improved significantly.

  11. SINGLE EVENT EFFECTS TEST FACILITY AT OAK RIDGE NATIONAL LABORATORY

    Energy Technology Data Exchange (ETDEWEB)

    Riemer, Bernie [ORNL; Gallmeier, Franz X [ORNL; Dominik, Laura J [ORNL

    2015-01-01

    Increasing use of microelectronics of ever diminishing feature size in avionics systems has led to a growing Single Event Effects (SEE) susceptibility arising from the highly ionizing interactions of cosmic rays and solar particles. Single event effects caused by atmospheric radiation have been recognized in recent years as a design issue for avionics equipment and systems. To ensure a system meets all its safety and reliability requirements, SEE induced upsets and potential system failures need to be considered, including testing of the components and systems in a neutron beam. Testing of ICs and systems for use in radiation environments requires the utilization of highly advanced laboratory facilities that can run evaluations on microcircuits for the effects of radiation. This paper provides a background of the atmospheric radiation phenomenon and the resulting single event effects, including single event upset (SEU) and latch up conditions. A study investigating requirements for future single event effect irradiation test facilities and developing options at the Spallation Neutron Source (SNS) is summarized. The relatively new SNS with its 1.0 GeV proton beam, typical operation of 5000 h per year, expertise in spallation neutron sources, user program infrastructure, and decades of useful life ahead is well suited for hosting a world-class SEE test facility in North America. Emphasis was put on testing of large avionics systems while still providing tunable high flux irradiation conditions for component tests. Makers of ground-based systems would also be served well by these facilities. Three options are described; the most capable, flexible, and highest-test-capacity option is a new stand-alone target station using about one kW of proton beam power on a gas-cooled tungsten target, with dual test enclosures. Less expensive options are also described.

  12. Factors controlling short-term soil microbial response after laboratory heating. Preliminary results

    Science.gov (United States)

    Jiménez-Compán, Elizabeth; Jiménez-Morillo, Nicasio; Jordán, Antonio; Bárcenas-Moreno, Gema

    2015-04-01

    Soil microbial response after fire is controlled by numerous variables which conclude with a mosaic of results depending on organic carbon alterations or pH fire-induced changes. This fact has complicated the studies focused on post-fire microbial response, compiling high variability of opposite result in the bibliography. Soil laboratory heating cannot emulate a real wildfire effect on soil but lead us the possibility to control several variables and it is a valid tool to clarify the relative weight of different factors controlling microbial response after soil heating. In this preliminary study different heated treatments were applied to unaltered forest soil samples, obtaining 4 different heating treatments to simulate a range of fire intensities: unaltered-control (UH), and soil heated at 300, 450 and 500 °C. In order to isolate possible nutrient availability or pH heating-induced changes, different culture media were prepared using soil:water extract from each heating treatments and adding different supplements to obtain the total of 11 different culture media: unheated soil without supplements (UH-N-), unheated soil with nutrient supplement (UH-N+), soil heated at 300 °C without supplements (300-N-), soil heated at 300 °C with nutrient supplement (300-N+), soil heated at 300 °C with nutrient supplement and pH-buffered (300-N+pH); soil heated at 450 °C without supplements (450-N-), soil heated at 450 °C with nutrient supplement (450-N+), soil heated at 450 °C with nutrient supplement and pH-buffered (450-N+); soil heated at 500 °C without supplements (500-N-), soil heated at 500 °C with nutrient supplement (500-N+), soil heated at 500 °C with nutrient supplement and pH-buffered (500-N+). Each media was inoculated with different dilutions of a microbial suspension from the original unaltered soil, and the abundance of viable and cultivable microorganisms were measured by plate count method. In addition, the analysis of heating-induced soil organic

  13. Laboratory Performance Testing of Residential Window Air Conditioners

    Energy Technology Data Exchange (ETDEWEB)

    Winkler, J.; Booten, C.; Christensen, D.; Tomerlin, J.

    2013-03-01

    Window air conditioners are the dominant cooling product for residences, in terms of annual unit sales. They are inexpensive, portable and can be installed by the owner. For this reason, they are an attractive solution for supplemental cooling, for retrofitting air conditioning into a home which lacks ductwork, and for renters. Window air conditioners for sale in the United States are required to meet very modest minimum efficiency standards. Four window air conditioners' performance were tested in the Advanced HVAC Systems Laboratory on NREL's campus in Golden, CO. In order to separate and study the refrigerant system's performance, the unit's internal leakage pathways, the unit's fanforced ventilation, and the leakage around the unit resulting from installation in a window, a series of tests were devised that focused on each aspect of the unit's performance. These tests were designed to develop a detailed performance map to determine whole-house performance in different climates. Even though the test regimen deviated thoroughly from the industry-standard ratings test, the results permit simple calculation of an estimated rating for both capacity and efficiency that would result from a standard ratings test. Using this calculation method, it was found that the three new air conditioners' measured performance was consistent with their ratings. This method also permits calculation of equivalent SEER for the test articles. Performance datasets were developed across a broad range of indoor and outdoor operating conditions, and used them to generate performance maps.

  14. Preliminary test results from the CELSS Test Facility Engineering Development Unit

    Science.gov (United States)

    Kliss, Mark H.; Macelroy, R. D.; Blackwell, C. C.; Borchers, B. A.; Drews, M. E.; Longabaugh, J. R.; Yendler, B. S.; Zografos, A. I.

    1994-01-01

    As part of the NASA Controlled Ecological Life Support System (CELSS) Program, a CELSS Test Facility (CTF) is being planned for installation on the Space Station. The CTF will be used to provide data on the productivity and efficiency of a variety of CELSS higher plant crops grown in the microgravity environment of the Space Station. Tight environmental control will be maintained while data on gas exchange rates and biomass accumulation rates are collected. In order to obtain an early realistic determination of the subsystem and system requirements necessary to provide the environmental conditions specified for CTF crop productivity experiments, an Engineering Development Unit (EDU) has been designed, constructed and is in the process of subsystem and system testing at NASA Ames Research Center. The EDU is a ground test-bed which will be used to characterize the integrated performance of major subsystem technologies, to evaluate hardware candidates and control strategies required for the CTF, and to further define the ability to meet CTF requirements within present Space Station constraints. This paper reviews the functional requirements for the EDU, and focuses on the performance evaluation and test results of the various subsystems. Preliminary integrated performance results and control system operation are addressed, and plans for future science and technology testing are discussed.

  15. EVA Development and Verification Testing at NASA's Neutral Buoyancy Laboratory

    Science.gov (United States)

    Jairala, Juniper C.; Durkin, Robert; Marak, Ralph J.; Sipila, Stepahnie A.; Ney, Zane A.; Parazynski, Scott E.; Thomason, Arthur H.

    2012-01-01

    As an early step in the preparation for future Extravehicular Activities (EVAs), astronauts perform neutral buoyancy testing to develop and verify EVA hardware and operations. Neutral buoyancy demonstrations at NASA Johnson Space Center's Sonny Carter Training Facility to date have primarily evaluated assembly and maintenance tasks associated with several elements of the International Space Station (ISS). With the retirement of the Shuttle, completion of ISS assembly, and introduction of commercial players for human transportation to space, evaluations at the Neutral Buoyancy Laboratory (NBL) will take on a new focus. Test objectives are selected for their criticality, lack of previous testing, or design changes that justify retesting. Assembly tasks investigated are performed using procedures developed by the flight hardware providers and the Mission Operations Directorate (MOD). Orbital Replacement Unit (ORU) maintenance tasks are performed using a more systematic set of procedures, EVA Concept of Operations for the International Space Station (JSC-33408), also developed by the MOD. This paper describes the requirements and process for performing a neutral buoyancy test, including typical hardware and support equipment requirements, personnel and administrative resource requirements, examples of ISS systems and operations that are evaluated, and typical operational objectives that are evaluated.

  16. Standard test method for laboratory evaluation of magnesium sacrificial anode test specimens for underground applications

    CERN Document Server

    American Society for Testing and Materials. Philadelphia

    1997-01-01

    1.1 This test method covers a laboratory procedure that measures the two fundamental performance properties of magnesium sacrificial anode test specimens operating in a saturated calcium sulfate, saturated magnesium hydroxide environment. The two fundamental properties are electrode (oxidation potential) and ampere hours (Ah) obtained per unit mass of specimen consumed. Magnesium anodes installed underground are usually surrounded by a backfill material that typically consists of 75 % gypsum (CaSO4·2H2O), 20 % bentonite clay, and 5 % sodium sulfate (Na2SO4). The calcium sulfate, magnesium hydroxide test electrolyte simulates the long term environment around an anode installed in the gypsum-bentonite-sodium sulfate backfill. 1.2 This test method is intended to be used for quality assurance by anode manufacturers or anode users. However, long term field performance properties may not be identical to property measurements obtained using this laboratory test. Note 1—Refer to Terminology G 15 for terms used ...

  17. Laboratory Testing of Active and Passive UHF RFID Tags

    Directory of Open Access Journals (Sweden)

    Kolarovszki Peter

    2016-06-01

    Full Text Available This article deals with research of laboratory testing by active and passive UHF tags and therefore mutual coexistence of active and passive RFID technology, which is a part of automatic identification and data capture. In this article we would like to describe an identification of transport unit based on passive technology and also by active technology. We would like to specify, how this technologies can work together and in which application focuses on postal and logistics. All results are verified by measurement in our AIDC laboratory, which is located at the University of Žilina. Our research contains different types of measurements in order to point out the possible influence of these two technologies. The results of our research bring the new point of view and indicate the ways using of UHF RFID technology in postal and logistics applications. At the end of this article is characterized the utilization of the RFID technology in postal logistics chain by using both passive and active technologies.

  18. Laboratory tests of oil spreading under the ice cover

    Energy Technology Data Exchange (ETDEWEB)

    Rytkoenen, J.; Liukkonen, S.; Riipi, T. [VTT Manufacturing Technology, Espoo (Finland)

    1998-07-01

    A laboratory study on oil spreading and drifting under ice was conducted by VTT Manufacturing Technology, Finland. The aim of the study was to find out threshold conditions for the oil movement under ice. The oil was released under ice in calm water and the spreading of the oil slick under the bottom of the ice was investigated. In the oil drifting part, oil drifting velocities under level ice in steady water flow, water flow velocities making oil to submerge from open water to under ice and water velocities making oil to escape from under ice ridges were studied. This paper describes the oil spreading part of the study. The study included four types of oil, namely the fresh and pre-altered North Sea Brent crude oil, lubrication oil and diesel fuel oil. All the measurements were taken in water under ice, thus at the temperature of zero Celcius. In the level ice studies, three different ice bottom roughnesses were tested. (author)

  19. Test and Validation of the Mars Science Laboratory Robotic Arm

    Science.gov (United States)

    Robinson, M.; Collins, C.; Leger, P.; Kim, W.; Carsten, J.; Tompkins, V.; Trebi-Ollennu, A.; Florow, B.

    2013-01-01

    The Mars Science Laboratory Robotic Arm (RA) is a key component for achieving the primary scientific goals of the mission. The RA supports sample acquisition by precisely positioning a scoop above loose regolith or accurately preloading a percussive drill on Martian rocks or rover-mounted organic check materials. It assists sample processing by orienting a sample processing unit called CHIMRA through a series of gravity-relative orientations and sample delivery by positioning the sample portion door above an instrument inlet or the observation tray. In addition the RA facilitates contact science by accurately positioning the dust removal tool, Alpha Particle X-Ray Spectrometer (APXS) and the Mars Hand Lens Imager (MAHLI) relative to surface targets. In order to fulfill these seemingly disparate science objectives the RA must satisfy a variety of accuracy and performance requirements. This paper describes the necessary arm requirement specification and the test campaign to demonstrate these requirements were satisfied.

  20. Sandia National Laboratories' new high level acoustic test facility

    Energy Technology Data Exchange (ETDEWEB)

    Rogers, J. D.; Hendrick, D. M.

    1989-01-01

    A high intensity acoustic test facility has been designed and is under construction at Sandia National Laboratories in Albuquerque, NM. The chamber is designed to provide an acoustic environment of 154dB (re 20 {mu}Pa) overall sound pressure level over the bandwidth of 50 Hz to 10,000 Hz. The chamber has a volume of 16,000 cubic feet with interior dimensions of 21.6 ft {times} 24.6 ft {times} 30 ft. The construction of the chamber should be complete by the summer of 1990. This paper discusses the design goals and constraints of the facility. The construction characteristics are discussed in detail, as are the acoustic performance design characteristics. The authors hope that this work will help others in designing acoustic chambers. 12 refs., 6 figs.

  1. Confidence Intervals for Laboratory Sonic Boom Annoyance Tests

    Science.gov (United States)

    Rathsam, Jonathan; Christian, Andrew

    2016-01-01

    Commercial supersonic flight is currently forbidden over land because sonic booms have historically caused unacceptable annoyance levels in overflown communities. NASA is providing data and expertise to noise regulators as they consider relaxing the ban for future quiet supersonic aircraft. One deliverable NASA will provide is a predictive model for indoor annoyance to aid in setting an acceptable quiet sonic boom threshold. A laboratory study was conducted to determine how indoor vibrations caused by sonic booms affect annoyance judgments. The test method required finding the point of subjective equality (PSE) between sonic boom signals that cause vibrations and signals not causing vibrations played at various amplitudes. This presentation focuses on a few statistical techniques for estimating the interval around the PSE. The techniques examined are the Delta Method, Parametric and Nonparametric Bootstrapping, and Bayesian Posterior Estimation.

  2. Evidence of sulphonamide residues by rapid laboratory test

    Directory of Open Access Journals (Sweden)

    Damir Kaša

    2004-04-01

    Full Text Available In addition to the significant role in the treatment of bacterial diseases, primarily mastitis, intestinal infections and pneumonia, sulphonamides are used as fodder additives. The disadvantage of antimicrobial therapy in dairy cows is the residue presence, of biologically active substances, in milk and milk products. The purpose of this paper is to control milk for sulphonamide residues in relation to the amounts as permitted by the Regulations (OfficialGazette of the Republic of Croatia No. 39/2003. To determine sulphonamides, the laboratory test LabSULFAmilk, manufactured by Frank analab d.o.o., was used. Positive reaction to sulphonamide residues was found in 10 % of the examined samples.

  3. The use of laboratory tests in the diagnosis of SLE.

    Science.gov (United States)

    Egner, W

    2000-06-01

    ANA IIF is an effective screening assay in patients with clinical features of SLE and will detect most anti-ssDNA, anti-dsDNA, ENAs, and other autoantibodies. False positives are common. The clinical importance cannot be extrapolated from the ANA titre or pattern, although higher titres (> 1/160) are more likely to be important. HEp-2 cells are the most sensitive substrate for ANA detection, but this must be balanced against an increased incidence of insignificant positivity. ANA positive samples should be subjected to more specific assays for the diagnosis of SLE. A combination of ENA (Ro/La/Sm/RNP) and dsDNA assays will detect most patients with SLE as long as the characteristics of the assays used are well understood. ESR and CRP measurements provide useful additional information. Sjogren's syndrome and MCTD will produce overlapping serology with SLE, and anti-dsDNA titres are sometimes seen in autoimmune hepatitis and rheumatoid arthritis. All results should be reported in the light of the clinical details, by an experienced immunologist. A suggested diagnostic protocol is outlined in fig 1. The type of assay used crucially influences the predictive value of the tests. ELISA technology dominates routine laboratory practice, but tends to produce more false positive and true weak positive results, which may reduce the PPV of the test. This can be minimised by using IgG specific conjugates and careful assay validation. The NPV for SLE [figure: see text] is high for most assays but the PPV varies. Where necessary, laboratories should use crithidia or Farr dsDNA assays to confirm dubious ELISA dsDNA results, and ID/IB to confirm dubious ENA results. For monitoring, a precise, quantitative assay is required. It is unclear whether the detection of IgM or low affinity antibodies has a role here. A combination of anti-dsDNA, C3, C4, CRP, and ESR assays provides the most useful clinical information. Anti-ssDNA assays are likely to be useful, and are potentially more

  4. Boxing and mixed martial arts: preliminary traumatic neuromechanical injury risk analyses from laboratory impact dosage data.

    Science.gov (United States)

    Bartsch, Adam J; Benzel, Edward C; Miele, Vincent J; Morr, Douglas R; Prakash, Vikas

    2012-05-01

    In spite of ample literature pointing to rotational and combined impact dosage being key contributors to head and neck injury, boxing and mixed martial arts (MMA) padding is still designed to primarily reduce cranium linear acceleration. The objects of this study were to quantify preliminary linear and rotational head impact dosage for selected boxing and MMA padding in response to hook punches; compute theoretical skull, brain, and neck injury risk metrics; and statistically compare the protective effect of various glove and head padding conditions. An instrumented Hybrid III 50th percentile anthropomorphic test device (ATD) was struck in 54 pendulum impacts replicating hook punches at low (27-29 J) and high (54-58 J) energy. Five padding combinations were examined: unpadded (control), MMA glove-unpadded head, boxing glove-unpadded head, unpadded pendulum-boxing headgear, and boxing glove-boxing headgear. A total of 17 injury risk parameters were measured or calculated. All padding conditions reduced linear impact dosage. Other parameters significantly decreased, significantly increased, or were unaffected depending on padding condition. Of real-world conditions (MMA glove-bare head, boxing glove-bare head, and boxing glove-headgear), the boxing glove-headgear condition showed the most meaningful reduction in most of the parameters. In equivalent impacts, the MMA glove-bare head condition induced higher rotational dosage than the boxing glove-bare head condition. Finite element analysis indicated a risk of brain strain injury in spite of significant reduction of linear impact dosage. In the replicated hook punch impacts, all padding conditions reduced linear but not rotational impact dosage. Head and neck dosage theoretically accumulates fastest in MMA and boxing bouts without use of protective headgear. The boxing glove-headgear condition provided the best overall reduction in impact dosage. More work is needed to develop improved protective padding to minimize

  5. A spatially-dynamic preliminary risk assessment of the American peregrine falcon at the Los Alamos National Laboratory (version 1)

    Energy Technology Data Exchange (ETDEWEB)

    Gallegos, A.F.; Gonzales, G.J.; Bennett, K.D. [and others

    1997-06-01

    The Endangered Species Act and the Record of Decision on the Dual Axis Radiographic Hydrodynamic Test Facility at the Los Alamos National Laboratory require protection of the American peregrine falcon. A preliminary risk assessment of the peregrine was performed using a custom FORTRAN model and a geographical information system. Estimated doses to the falcon were compared against toxicity reference values to generate hazard indices. Hazard index results indicated no unacceptable risk to the falcon from the soil ingestion pathway, including a measure of cumulative effects from multiple contaminants that assumes a linear additive toxicity type. Scaling home ranges on the basis of maximizing falcon height for viewing prey decreased estimated risk by 69% in a canyons-based home range and increased estimated risk by 40% in a river-based home range. Improving model realism by weighting simulated falcon foraging based on distance from potential nest sites decreased risk by 93% in one exposure unit and by 82% in a second exposure unit. It was demonstrated that choice of toxicity reference values can have a substantial impact on risk estimates. Adding bioaccumulation factors for several organics increased partial hazard quotients by a factor of 110, but increased the mean hazard index by only 0.02 units. Adding a food consumption exposure pathway in the form of biomagnification factors for 15 contaminants of potential ecological concern increased the mean hazard index to 1.16 ({+-} 1.0), which is above the level of acceptability (1.0). Aroclor-1254, dichlorodiphenyltrichlorethane (DDT) and dichlorodiphenylethelyne (DDE) accounted for 81% of the estimated risk that includes soil ingestion and food consumption Contaminant pathways and a biomagnification component. Information on risk by specific geographical location was generated, which can be used to manage contaminated areas, falcon habitat, facility siting, and/or facility operations. 123 refs., 10 figs., 2 tabs.

  6. Description and Preliminary Testing of the CDSN Seismic Sensor Systems

    Science.gov (United States)

    Peterson, Jon; Tilgner, Edwin E.

    1985-01-01

    INTRODUCTION The China Digital Seismograph Network (CDSN) is being designed and installed to provide the People's Republic of China with the facilities needed to create a national digital database for earthquake research. The CDSN, which is being developed jointly by the PRC State Seismological Bureau and the U.S. Geological Survey, will consist initially of nine digitally-recording seismograph stations, a data management system to be used for compiling network-day tapes, and a depot maintenance center. Data produced by the network will be shared with research scientists throughout the world. A national seismograph network must be designed to support a variety of research objectives. From this standpoint, the choices and tradeoffs involved in specifying signal bandwidth, resolution, and dynamic range are the most important decisions in system design. As in the case of the CDSN, these decisions are made during the selection and design of the seismic sensor system and encoder components. The purpose of this report is to describe the CDSN sensor systems, their important signal characteristics, and the results of preliminary tests that have been performed on the instruments. Four overlapping data bands will be recorded at each station: short period (SP), broadband (BB), long period (LP), and very long period (VLP). Amplitude response curves are illustrated in Figure I. Vertical and horizontal components will be recorded for each data band. The SP and LP channels will be recorded with sufficient sensitivities to resolve earth background noise at seismically quiet sites. The BB channels will have a lower sensitivity and are intended for broadband recording of moderate-to-large body-wave signals and for increasing the effective amplitude range in the short- and long-period bands. The VLP channel does not provide additional spectral coverage at long periods; its purpose is to make use of on-site filtration and decimation to reduce post processing requirements for VLP

  7. Preliminary stress characterization for an in-situ stimulation experiment at the Grimsel Underground Laboratory

    Science.gov (United States)

    Krietsch, Hannes; Doetsch, Joseph; Gischig, Valentin; Amann, Florian; Jalali, Mohammadreza; Madonna, Claudio; Evans, Keith; Valley, Benoit; Giardini, Domenico; Wiemer, Stefan; Maurer, Hansruedi; Loew, Simon

    2016-04-01

    A decameter-scale in-situ stimulation experiment is currently being executed at the Grimsel Test Site in Switzerland, spanning from hydraulic fracturing to controlled fault-slip experiments. For the feasibility of this project the in-situ stress tensor is of foremost importance. Therefore a unique stress characterization campaign combining stress relief methods (overcoring of USBM and CSIRO-HI probes) with hydraulic fracturing (HF) and hydraulic testing on pre-existing fractures (HTPF) in three boreholes was conducted in a first phase of this project. During all hydraulic stress measurements, micro-seismicity was monitored and localized in real time utilizing a dense network of piezo-electric sensors. In this contribution, we present preliminary results of the stress characterization and compare the derived stress tensor with previous estimates of the stress state. The stress characterization campaign was conducted in three boreholes, one sub-vertical and two sub-horizontal boreholes, assuming that the sub-vertical and one sub-horizontal are parallel to a principal stress component. A major task in this contribution is the integration of the different stress characterization methods. Our results of the different methods (overcoring and HF) are largely consistent, but disagree with some of the previous stress orientation estimates. From the new campaign the overcoring measurements indicate a sub-horizontal sigma1 of 17.3 MPa with a strike of 145°, a sigma2 of 9.7 MPa with 241°/69° and a sigma3 of 8.3 MPa with 055°/21° using an isotropic approach for inversion calculation. Whereas the USBM-Probe measures a projection of the principal stresses in a plane normal to borehole axis, the CSIRO-HI Probe provides the real 3D stress tensor. The HF and HTPF measurements indicate a far-field minimum horizontal stress between 8.7 and 9.1 MPa, consistent with the overcoring. Principal stresses, estimated by location of micro-seismic events during HF and HTPF, suggest that

  8. 75 FR 39954 - Oversight of Laboratory Developed Tests; Public Meeting; Change of Meeting Location

    Science.gov (United States)

    2010-07-13

    ... HUMAN SERVICES Food and Drug Administration Oversight of Laboratory Developed Tests; Public Meeting... entitled ``Oversight of Laboratory Developed Tests.'' A new address is given for those attending the public... interested stakeholders to discuss the agency's oversight of laboratory developed tests. FDA announced in...

  9. Transportable Heavy Duty Emissions Testing Laboratory and Research Program

    Energy Technology Data Exchange (ETDEWEB)

    David Lyons

    2008-03-31

    The objective of this program was to quantify the emissions from heavy-duty vehicles operating on alternative fuels or advanced fuel blends, often with novel engine technology or aftertreatment. In the first year of the program West Virginia University (WVU) researchers determined that a transportable chassis dynamometer emissions measurement approach was required so that fleets of trucks and buses did not need to be ferried across the nation to a fixed facility. A Transportable Heavy-Duty Vehicle Emissions Testing Laboratory (Translab) was designed, constructed and verified. This laboratory consisted of a chassis dynamometer semi-trailer and an analytic trailer housing a full scale exhaust dilution tunnel and sampling system which mimicked closely the system described in the Code of Federal Regulations for engine certification. The Translab was first used to quantify emissions from natural gas and methanol fueled transit buses, and a second Translab unit was constructed to satisfy research demand. Subsequent emissions measurement was performed on trucks and buses using ethanol, Fischer-Tropsch fuel, and biodiesel. A medium-duty chassis dynamometer was also designed and constructed to facilitate research on delivery vehicles in the 10,000 to 20,000lb range. The Translab participated in major programs to evaluate low-sulfur diesel in conjunction with passively regenerating exhaust particulate filtration technology, and substantial reductions in particulate matter were recorded. The researchers also participated in programs to evaluate emissions from advanced natural gas engines with closed loop feedback control. These natural gas engines showed substantially reduced levels of oxides of nitrogen. For all of the trucks and buses characterized, the levels of carbon monoxide, oxides of nitrogen, hydrocarbons, carbon dioxide and particulate matter were quantified, and in many cases non-regulated species such as aldehydes were also sampled. Particle size was also

  10. 南京市35家实验室糖化血红蛋白A1c检测结果的初步调查%Preliminary investigation on the test results of glycosylated hemoglobin Alc from 35 laboratories in Nanjing

    Institute of Scientific and Technical Information of China (English)

    徐志晔; 张葵; 魏红霞

    2012-01-01

    目的 了解南京市各医疗机构糖化血红蛋白A1c(HbA1c)检测方法及结果的可比性,分析室间变异和测定偏差,初步探讨误差原因和改进措施,为做好实验室结果互认工作提供依据.方法 制备新鲜混合全血样本,确立靶值,并分发至南京市35家实验室,24h内完成检测;按方法学分组统计分析各实验室结果;分别按美国病理学家协会(College of American Pathologists,CAP)的推荐标准(靶值±8%偏差)和“可接受总误差”标准(靶值±3.9%偏差)来判断结果是否可接受;以水平2样本HbA1c靶值6.5%为例观察结果的分布.结果 高效液相色谱(HPLC)组CV为2.91%~4.48%,免疫比浊组为9.66%~11.10%,低压液相色谱(LPLC)组为11.6%~16.1%,微粒色谱组为10.4% ~20.3%;按CAP标准以靶值±8%偏差来判断,三级医疗机构实验室合格率为78.6%,二级医疗机构实验室为31.5%;以靶值±3.9%偏差来判断时,三级医疗机构实验室合格率为42.8%,二级医疗机构实验室为10.5%;水平2样本在±8%偏差之内的有25家,占71.4% (25/35);在±3.9%偏差内的有15家,占42.9%(15/35).结论 南京市三级以上医疗机构HbA1c检测结果较一致,二级医疗机构检测结果差异较大;方法学差异在HbA1c检测中的确存在,但严格的室内质控和实验室间比对才是保证结果准确一致最重要的因素;各实验室特别是二级以下医疗机构实验室的质控意识仍有待加强,实验室间比对工作也有待进一步向基层医疗机构推广.%Objective To investigate the test methods and the comparability of the results of glycosylated hemoglobin Ale (HbAlc) from the clinical laboratories in Nanjing, analyze the inter-laboratory variation and the determination deviation, and explore the possible sources of error and improvement measures in order to provide the evidence for the mutual accredit of results from different laboratories. Methods Fresh whole

  11. MOBLAB: a mobile laboratory for testing real-time vision-based systems in path monitoring

    Science.gov (United States)

    Cumani, Aldo; Denasi, Sandra; Grattoni, Paolo; Guiducci, Antonio; Pettiti, Giuseppe; Quaglia, Giorgio

    1995-01-01

    In the framework of the EUREKA PROMETHEUS European Project, a Mobile Laboratory (MOBLAB) has been equipped for studying, implementing and testing real-time algorithms which monitor the path of a vehicle moving on roads. Its goal is the evaluation of systems suitable to map the position of the vehicle within the environment where it moves, to detect obstacles, to estimate motion, to plan the path and to warn the driver about unsafe conditions. MOBLAB has been built with the financial support of the National Research Council and will be shared with teams working in the PROMETHEUS Project. It consists of a van equipped with an autonomous power supply, a real-time image processing system, workstations and PCs, B/W and color TV cameras, and TV equipment. This paper describes the laboratory outline and presents the computer vision system and the strategies that have been studied and are being developed at I.E.N. `Galileo Ferraris'. The system is based on several tasks that cooperate to integrate information gathered from different processes and sources of knowledge. Some preliminary results are presented showing the performances of the system.

  12. Internship at NASA Kennedy Space Center's Cryogenic Test laboratory

    Science.gov (United States)

    Holland, Katherine

    2013-01-01

    NASA's Kennedy Space Center (KSC) is known for hosting all of the United States manned rocket launches as well as many unmanned launches at low inclinations. Even though the Space Shuttle recently retired, they are continuing to support unmanned launches and modifying manned launch facilities. Before a rocket can be launched, it has to go through months of preparation, called processing. Pieces of a rocket and its payload may come in from anywhere in the nation or even the world. The facilities all around the center help integrate the rocket and prepare it for launch. As NASA prepares for the Space Launch System, a rocket designed to take astronauts beyond Low Earth Orbit throughout the solar system, technology development is crucial for enhancing launch capabilities at the KSC. The Cryogenics Test Laboratory at Kennedy Space Center greatly contributes to cryogenic research and technology development. The engineers and technicians that work there come up with new ways to efficiently store and transfer liquid cryogens. NASA has a great need for this research and technology development as it deals with cryogenic liquid hydrogen and liquid oxygen for rocket fuel, as well as long term space flight applications. Additionally, in this new era of space exploration, the Cryogenics Test Laboratory works with the commercial sector. One technology development project is the Liquid Hydrogen (LH2) Ground Operations Demonstration Unit (GODU). LH2 GODU intends to demonstrate increased efficiency in storing and transferring liquid hydrogen during processing, loading, launch and spaceflight of a spacecraft. During the Shuttle Program, only 55% of hydrogen purchased was used by the Space Shuttle Main Engines. GODU's goal is to demonstrate that this percentage can be increased to 75%. Figure 2 shows the GODU layout when I concluded my internship. The site will include a 33,000 gallon hydrogen tank (shown in cyan) with a heat exchanger inside the hydrogen tank attached to a

  13. Laboratory testing of a lethal ovitrap for Aedes aegypti.

    Science.gov (United States)

    Zeichner, B C; Perich, M J

    1999-07-01

    Laboratory tests were conducted to determine the feasibility of making the mosquito ovitrap lethal to Aedes aegypti (L.) when they attempt to oviposit in the trap. Heavy-weight velour paper strips (2.54 x 11 cm) were used as an alternative to the wooden paddle normally provided as a substrate for mosquito oviposition. The paper strips were pretreated with insecticide solutions and allowed to dry before being used in oviposition cups of 473 ml capacity, filled with water initially to within 2.5 cm of the brim. Insecticides chosen for their quick knock-down efficacy were bendiocarb 76% WP (1.06 mg a.i./strip) and four pyrethroids: permethrin 25% WP (0.16 mg a.i./strip), deltamethin 4.75% SC (0.87 mg a.i./strip), cypermethrin 40% WP (2.81 mg a.i./strip), and cyfluthrin 20% WP (0.57 mg a.i./ strip). For experimental evaluation, two oviposition cups (one with an insecticide-treated strip and one with an untreated strip) were placed in cages (cubic 30 cm) with gravid female Ae. aegypti mosquitoes (aged 6-8 days) from a susceptible laboratory strain. Mortality-rates of female mosquitoes were 45% for bendiocarb, 47% for permethrin, 98% for deltamethrin, 100% for cypermethrin, and 100% for cyfluthrin. Young instar larvae added to the treated cups died within 2h. After water evaporation from the cups for 38 days, fresh mosquito females had access to previously submerged portions of the velour paper paddle, and mortality rates of 59% or more occurred. Cups that had water (360 ml) dripped into them, to simulate rain, produced female mosquito mortality rates of > 50% and all larvae died within 3 h of being added. These tests demonstrate that the ovitrap can be made lethal to both adults and larvae by insecticidal treatment of the ovistrip. Field efficacy trials are underway in Brazil to access the impact of this simple, low-cost, environmentally benign approach on populations of the dengue vector Ae. aegypti.

  14. Plans and Preliminary Results of Fundamental Studies of Ice Crystal Icing Physics in the NASA Propulsion Systems Laboratory

    Science.gov (United States)

    Struk, Peter; Tsao, Jen-Ching; Bartkus, Tadas

    2017-01-01

    This paper describes plans and preliminary results for using the NASA Propulsion Systems Lab (PSL) to experimentally study the fundamental physics of ice-crystal ice accretion. NASA is evaluating whether this facility, in addition to full-engine and motor-driven-rig tests, can be used for more fundamental ice-accretion studies that simulate the different mixed-phase icing conditions along the core flow passage of a turbo-fan engine compressor. The data from such fundamental accretion tests will be used to help develop and validate models of the accretion process. This paper presents data from some preliminary testing performed in May 2015 which examined how a mixed-phase cloud could be generated at PSL using evaporative cooling in a warmer-than-freezing environment.

  15. Preliminary Test Estimators and Phi-divergence Measures in Pooling Binomial Data

    Directory of Open Access Journals (Sweden)

    N. Martin

    2012-07-01

    Full Text Available Two independent random samples are drawn from two Binomial populations with parameters theta1 and  theta2 respectively. Ahmed (1991 considered a preliminary test estimator based on maximum likelihood estimator for estimating theta1 when it is suspected that theta1=theta2.  In this paper we combine minimum phi-divergence estimators as well as phi-divergence test statistics in order to define a preliminary phi-divergence test estimators. These new estimators are compared with the classical estimator as well as the pooled estimator.

  16. 9 CFR 54.11 - Approval of laboratories to run official scrapie tests and official genotype tests.

    Science.gov (United States)

    2010-01-01

    ... 9 Animals and Animal Products 1 2010-01-01 2010-01-01 false Approval of laboratories to run official scrapie tests and official genotype tests. 54.11 Section 54.11 Animals and Animal Products ANIMAL... laboratories to run official scrapie tests and official genotype tests. (a) State, Federal, and...

  17. Preliminary Options Assessment of Versatile Irradiation Test Reactor

    Energy Technology Data Exchange (ETDEWEB)

    Sen, Ramazan Sonat [Idaho National Lab. (INL), Idaho Falls, ID (United States)

    2017-01-01

    The objective of this report is to summarize the work undertaken at INL from April 2016 to January 2017 and aimed at analyzing some options for designing and building a versatile test reactor; the scope of work was agreed upon with DOE-NE. Section 2 presents some results related to KNK II and PRISM Mod A. Section 3 presents some alternatives to the VCTR presented in [ ] as well as a neutronic parametric study to assess the minimum power requirement needed for a 235U metal fueled fast test reactor capable to generate a fast (>100 keV) flux of 4.0 x 1015 n /cm2-s at the test location. Section 4 presents some results regarding a fundamental characteristic of test reactors, namely displacement per atom (dpa) in test samples. Section 5 presents the INL assessment of the ANL fast test reactor design FASTER. Section 6 presents a summary.

  18. Capability of the Gas Analysis and Testing Laboratory at the NASA Johnson Space Center

    Science.gov (United States)

    Broerman, Craig; Jimenez, Javier; Sweterlitsch, Jeff

    2012-01-01

    The Gas Analysis and Testing Laboratory is an integral part of the testing performed at the NASA Johnson Space Center. The Gas Analysis and Testing Laboratory is a high performance laboratory providing real time analytical instruments to support manned and unmanned testing. The lab utilizes precision gas chromatographs, gas analyzers and spectrophotometers to support the technology development programs within the NASA community. The Gas Analysis and Testing Laboratory works with a wide variety of customers and provides engineering support for user-specified applications in compressed gas, chemical analysis, general and research laboratory.

  19. Mycobacterium tuberculosis testing practices in hospital, commercial and state laboratories in the New England states.

    Science.gov (United States)

    Livingston, K A; Lobato, M N; Sosa, L E; Budnick, G E; Bernardo, J

    2011-09-01

    The mycobacterial laboratory is assuming an increasingly important role in tuberculosis (TB) control in the United States today. To assess mycobacterial laboratory capacity and practices in the New England states, USA. We surveyed 143 hospital and commercial laboratories and five of the six state public health laboratories in New England that offer testing services for Mycobacterium tuberculosis. The survey captured information on types of services offered and volume of testing, use of state laboratories for testing, and promptness of reporting results to TB control programs. State laboratories perform the majority of testing services, particularly for more specialized tests. All state laboratories surveyed perform species identification of acid-fast isolates, culture and first-line drug susceptibility testing. Less than 20% of hospital and commercial laboratories offer these services, and 78.6% of hospitals and commercial laboratories refer specimens to state laboratories for culture. Surveys of M. tuberculosis testing capacities in a region can help decision makers ensure maintenance of essential services. Hospital and commercial laboratories with lower testing volume might increase efficiency by referring more specimens to state laboratories. State health departments might consider organizing regional laboratory service networks to monitor the provision of services, improve efficiency and oversee quality improvement initiatives.

  20. 78 FR 46996 - Current List of Laboratories and Instrumented Initial Testing Facilities Which Meet Minimum...

    Science.gov (United States)

    2013-08-02

    ... 503 of Public Law 100-71. The ``Mandatory Guidelines for Federal Workplace Drug Testing Programs'', as... Laboratory Partnership, 245 Pall Mall Street, London, ONT, Canada N6A 1P4, 519-679-1630 Laboratory...: Centinela Hospital Airport Toxicology Laboratory) Pathology Associates Medical Laboratories, 110 West Cliff...

  1. 78 FR 39757 - Current List of Laboratories and Instrumented Initial Testing Facilities Which Meet Minimum...

    Science.gov (United States)

    2013-07-02

    ... 503 of Public Law 100-71. The ``Mandatory Guidelines for Federal Workplace Drug Testing Programs'', as... Laboratory Partnership, 245 Pall Mall Street, London, ONT, Canada N6A 1P4, 519-679-1630 Laboratory...: Centinela Hospital Airport Toxicology Laboratory) Pathology Associates Medical Laboratories, 110 West Cliff...

  2. Radiation Testing on State-of-the-Art CMOS: Challenges, Plans, and Preliminary Results

    Science.gov (United States)

    LaBel, Kenneth A.; Cohn, Lewis M.

    2009-01-01

    At GOMAC 2007 and 2008, we discussed a variety of challenges for radiation testing of modern semiconductor devices and technologies [1, 2]. In this presentation, we provide more specific details in this on-going investigation focusing on out-of-the-box lessons observed for providing radiation effects assurances as well as preliminary test results.

  3. Biosolid Soil Application: Toxicity Tests under Laboratory Conditions

    Directory of Open Access Journals (Sweden)

    Cintya Ap. Christofoletti

    2012-01-01

    Full Text Available A large volume of generated sewage sludge makes its disposal a problem. The usage of sludge in agriculture is highlighted by a number of advantages. However, heavy metals and other toxic compounds may exercise harmful effects to soil organisms. This study evaluated the possible toxic effects of a biosolid sample, under laboratory conditions, for 30 days, using diplopods Rhinocricus padbergi and plants Allium cepa (onion as test organisms. The data obtained demonstrated that the biosolid raw sample had genotoxic potential for Allium cepa root tip cells. In the diplopods exposed to biosolid sample, epithelium disorganization in the midgut and a reduction of the volume of the hepatic cells were observed after 7 days of exposure. After 30 days, the animals still showed a reduction of the volume of the hepatic cells, but in minor intensity. Allium cepa analysis showed genotoxicity, but this effect was reduced after 30 days of bioprocessing by diplopods. This study was important to know the effects as well as to determine how this waste could be applied concerning the soil living organisms and plants.

  4. Interteaching and the Testing Effect: A Preliminary Analysis

    Science.gov (United States)

    Lambert, Tonya; Saville, Bryan K.

    2012-01-01

    In a number of studies, interteaching has produced better student-learning outcomes than traditional teaching methods. Little research, however, has examined ways to make interteaching more effective. Research on the testing effect suggests that frequent testing may improve performance. Thus, including postdiscussion quizzes as a part of…

  5. Multi-laboratory precision of Marshall design related tests

    CSIR Research Space (South Africa)

    Denneman, E

    2008-07-01

    Full Text Available by different laboratories. The variability was of such a degree that it would influence design decisions or could lead to conflict over product acceptance. A study was undertaken to investigate the extent and consequences of the inter-laboratory variability...

  6. Preliminary Risk Assessment of the Southwestern Willow Flycatcher (Empidonax traillii extimus) at the Los Alamos National Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Gallegos, A.F.; Gonzales, G.J.; Bennett, K.D.; Mullen, M.A.; Foxx, T.S.

    1998-10-01

    The southwestern willow flycatcher (Empidonax traillii extimus) is the fourth threatened or endangered species to undergo a preliminary assessment for estimating potential risk from environmental contaminants at the Los Alamos National Laboratory. The assessments are being conducted as part of a three-year project to develop a habitat management plan for threatened and endangered species and species of concern at the Laboratory. For the preliminary assessment, estimated doses were compared against toxicity reference values to generate hazard indices (HIs). This assessment included a measure of cumulative effects from multiple contaminants (radionuclides, metals, and organic chemicals) to 100 simulated nest sites located within flycatcher potential habitat. Sources of contaminant values were 10,000-ft{sup 2} grid cells within an Ecological Exposure Unit (EEU). This EEU was estimated around the potential habitat and was based on the maximum home range for the fly catcher identified in the scientific literature. The tools used included a custom FORTRAN program, ECORSK5, and a geographic information system. Food consumption and soil ingestion contaminant pathways were addressed in the assessment. Using a four-category risk evaluation, HI results indicate no appreciable impact is expected to the southwestern willow flycatcher. Information on risk by specific geographical location was generated, which can be used to manage contaminated areas, flycatcher habitat, facility siting, and/or facility operations in order to maintain low levels of risk from contaminants.

  7. AGR-2 Irradiated Test Train Preliminary Inspection and Disassembly First Look

    Energy Technology Data Exchange (ETDEWEB)

    Ploger, Scott [Idaho National Lab. (INL), Idaho Falls, ID (United States); Demkowciz, Paul [Idaho National Lab. (INL), Idaho Falls, ID (United States); Harp, Jason [Idaho National Lab. (INL), Idaho Falls, ID (United States)

    2015-05-01

    The AGR 2 irradiation experiment began in June 2010 and was completed in October 2013. The test train was shipped to the Materials and Fuels Complex in July 2014 for post-irradiation examination (PIE). The first PIE activities included nondestructive examination of the test train, followed by disassembly of the test train and individual capsules and detailed inspection of the capsule contents, including the fuel compacts and their graphite fuel holders. Dimensional metrology was then performed on the compacts, graphite holders, and steel capsule shells. AGR 2 disassembly and metrology were performed with the same equipment used successfully on AGR 1 test train components. Gamma spectrometry of the intact test train gave a preliminary look at the condition of the interior components. No evidence of damage to compacts or graphite components was evident from the isotopic and gross gamma scans. Disassembly of the AGR 2 test train and its capsules was conducted rapidly and efficiently by employing techniques refined during the AGR 1 disassembly campaign. Only one major difficulty was encountered while separating the test train into capsules when thermocouples (of larger diameter than used in AGR 1) and gas lines jammed inside the through tubes of the upper capsules, which required new tooling for extraction. Disassembly of individual capsules was straightforward with only a few minor complications. On the whole, AGR 2 capsule structural components appeared less embrittled than their AGR 1 counterparts. Compacts from AGR 2 Capsules 2, 3, 5, and 6 were in very good condition upon removal. Only relatively minor damage or markings were visible using high resolution photographic inspection. Compact dimensional measurements indicated radial shrinkage between 0.8 to 1.7%, with the greatest shrinkage observed on Capsule 2 compacts that were irradiated at higher temperature. Length shrinkage ranged from 0.1 to 0.9%, with by far the lowest axial shrinkage on Capsule 3 compacts

  8. Preliminary test of effects of cognitive ability, experience, and teaching methods on Verbal Analogy Test scores.

    Science.gov (United States)

    Rosenberg, D; Willson-Quayle, A; Pasnak, R

    2000-06-01

    The methods from which one can choose when preparing for the GRE Verbal Analogies include books, software, audiotapes, and formal classroom instruction. What teaching method will work best for a given individual? To begin the search for an answer, Gray's test of reasoning ability was given to 28 undergraduates who also answered a questionnaire detailing their experience with analogies. They were randomly assigned to teaching conditions ranging from self-directed workbook study to intensive interactive assistance. No teaching method was superior overall, but interactions showed that (1) students who scored worst on the pretest improved the most, (2) those higher in cognitive functioning and experience performed better after intensive interactive assistance, and (3) those lower in both cognitive functioning and experience did significantly better with self-paced workbooks. This preliminary work suggests that it may be profitable to assess the prior experience and reasoning of potential students and adopt the methods for teaching formal operational thought found empirically to be most suitable.

  9. Preliminary low temperature tests of a digital signal processor

    Science.gov (United States)

    Zebulum, Ricardo S.; Ramesham, Rajeshuni; Stoica, Adrian; Keymeulen, Didier; Daud, Taher; Sekanina, Lukas

    2005-01-01

    This paper describes an initial experiment performed to assess the electrical behavior of the Innovative Integration board containing a Digital Signal Processor (DSP) with its JTAG (Blackhawk) connector at low temperatures. The objective of the experiment is to determine the lowest temperature at which the DSP can operate. The DSP was tested at various low-temperatures and a Genetic Algorithm was used as the DSP test program.

  10. CHALLENGE TESTS WITH LISTERIA MONOCYTOGENES IN SALAMI: PRELIMINARY RESULTS

    Directory of Open Access Journals (Sweden)

    R. Mioni

    2013-02-01

    Full Text Available Challenge tests are the preferable methodology to study the behaviour of Listeria monocytogenes on ready to eat foods, according to Regulation (EC 2073/2005. Challenge testing using L. monocytogenes in seasoned salami from different food business operators showed, after seasoning of the product, a count reduction of the inoculated organisms without any further growth of the pathogen; however differences of L. monocytogenes behaviour could be observed according to different production protocols.

  11. Information comparison of the effects of drugs on laboratory tests in drug labels and Young's book

    NARCIS (Netherlands)

    Geerts, A.F.; Koning, F.H. de; Egberts, T.C.; Smet, P.A. de; Solinge, W.W. van

    2012-01-01

    Abstract Background: The effects of drugs on laboratory tests may lead to misinterpretation of laboratory data, unnecessary tests, higher costs and missed diagnoses. This study compared the information on drug-laboratory effects (DLE) described in 200 drug labels with that in Young's book. Methods:

  12. 7 CFR 91.37 - Standard hourly fee rate for laboratory testing, analysis, and other services.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 3 2010-01-01 2010-01-01 false Standard hourly fee rate for laboratory testing... Charges § 91.37 Standard hourly fee rate for laboratory testing, analysis, and other services. (a) The standard hourly fee rate in this section for the individual laboratory analyses cover the costs of...

  13. Design and Preliminary Thermal Performance of the Mars Science Laboratory Rover Heat Exchangers

    Science.gov (United States)

    Mastropietro, A. J.; Beatty, John; Kelly, Frank; Birur, Gajanana; Bhandari, Pradeep; Pauken, Michael; Illsley, Peter; Liu, Yuanming; Bame, David; Miller, Jennifer

    2010-01-01

    The challenging range of proposed landing sites for the Mars Science Laboratory Rover requires a rover thermal management system that is capable of keeping temperatures controlled across a wide variety of environmental conditions. On the Martian surface where temperatures can be as cold as -123 degrees Centigrade and as warm as 38 degrees Centigrade, the Rover relies upon a Mechanically Pumped Fluid Loop (MPFL) and external radiators to maintain the temperature of sensitive electronics and science instruments within a -40 degrees Centigrade to 50 degrees Centigrade range. The MPFL also manages significant waste heat generated from the Rover power source, known as the Multi Mission Radioisotope Thermoelectric Generator (MMRTG). The MMRTG produces 110 Watts of electrical power while generating waste heat equivalent to approximately 2000 Watts. Two similar Heat Exchanger (HX) assemblies were designed to both acquire the heat from the MMRTG and radiate waste heat from the onboard electronics to the surrounding Martian environment. Heat acquisition is accomplished on the interior surface of each HX while heat rejection is accomplished on the exterior surface of each HX. Since these two surfaces need to be at very different temperatures in order for the MPFL to perform efficiently, they need to be thermally isolated from one another. The HXs were therefore designed for high in-plane thermal conductivity and extremely low through-thickness thermal conductivity by using aerogel as an insulator inside composite honeycomb sandwich panels. A complex assembly of hand welded and uniquely bent aluminum tubes are bonded onto the HX panels and were specifically designed to be easily mated and demated to the rest of the Rover Heat Recovery and Rejection System (RHRS) in order to ease the integration effort. During the cruise phase to Mars, the HX assemblies serve the additional function of transferring heat from the Rover MPFL to the separate Cruise Stage MPFL so that heat

  14. Zero-gravity cloud physics laboratory: Candidate experiments definition and preliminary concept studies

    Science.gov (United States)

    Eaton, L. R.; Greco, R. V.; Hollinden, A. B.

    1973-01-01

    The candidate definition studies on the zero-g cloud physics laboratory are covered. This laboratory will be an independent self-contained shuttle sortie payload. Several critical technology areas have been identified and studied to assure proper consideration in terms of engineering requirements for the final design. Areas include chambers, gas and particle generators, environmental controls, motion controls, change controls, observational techniques, and composition controls. This unique laboratory will allow studies to be performed without mechanical, aerodynamics, electrical, or other type techniques to support the object under study. This report also covers the candidate experiment definitions, chambers and experiment classes, laboratory concepts and plans, special supporting studies, early flight opportunities and payload planning data for overall shuttle payload requirements assessments.

  15. Standards for thyroid laboratory testing, and cognitive functions after menopause

    Directory of Open Access Journals (Sweden)

    Iwona Bojar

    2014-09-01

    Full Text Available Introduction : The aim of the study is to analyze the relationship between normative and non-normative thyroid tests (TSH, TT4, TT3, FT3, FT4, anti-TPO, anti-Tg, AB-TSHR and the level of cognitive functions in postmenopausal women. Material and methods: The study group consisted of 383 women from south-eastern Poland, aged 50-65 years. The cognitive functions were evaluated using a diagnostic instrument – Central Nervous System – Vital Signs (CNS-VS. Blood was collected for determination of the following parameters: TSH, TT4, TT3, FT3, FT4, anti-TPO, anti-Tg, AB-TSHR. Results: There were significant differences in NCI, executive functions, psychomotor speed, reaction time, complex attention and cognitive flexibility, depending on the normative and non-normative level of TSH. Women whose level of FT3 was at the lower limit of the normal range obtained poorer results in psychomotor speed, while subjects with levels of FT4 below the standard achieved significantly lower scores for this function. The relationship between NCI and cognitive functions, and the normative and non-normative anti-TPO results, showed significant differences in verbal memory, visual memory, processing speed and reaction time. The level of AB-TSHR reported as normal or above the norm significantly differentiated from the results of NCI, processing speed, executive functions, psychomotor speed, complex attention and cognitive flexibility. Conclusions : Concentrations of laboratory parameters assessing the thyroid function located within the upper limits of the normal range showed a different relationship with the cognitive performance than concentrations located within the lower limits of the standard.

  16. Putting Google Scholar to the Test: A Preliminary Study

    Science.gov (United States)

    Robinson, Mary L.; Wusteman, Judith

    2007-01-01

    Purpose: To describe a small-scale quantitative evaluation of the scholarly information search engine, Google Scholar. Design/methodology/approach: Google Scholar's ability to retrieve scholarly information was compared to that of three popular search engines: Ask.com, Google and Yahoo! Test queries were presented to all four search engines and…

  17. On Designing Construct Driven Situational Judgment Tests: Some Preliminary Recommendations

    Science.gov (United States)

    Guenole, Nigel; Chernyshenko, Oleksandr S.; Weekly, Jeff

    2017-01-01

    Situational judgment tests (SJTs) are widely agreed to be a measurement technique. It is also widely agreed that SJTs are a questionable methodological choice for measurement of psychological constructs, such as behavioral competencies, due to a lack of evidence supporting appropriate factor structures and high internal consistencies.…

  18. Preliminary tests of a damaged ship for CFD validation

    Directory of Open Access Journals (Sweden)

    Sungkyun Lee

    2012-06-01

    Full Text Available One of the most critical issues in naval architecture these days is the operational safety. Among many factors to be considered for higher safety level requirements, the hull stability in intact and damaged conditions is the first to ensure for both commercial and military vessels. Unlike the intact stability cases, the assessment of the damaged ship stability is very complicated physical phenomena. Therefore it is widely acknowledged that computational fluid dynamics (CFD methods are one of most feasible approaches. In order to develop better CFD methods for damaged ship stability assessment, it is essential to perform well-designed model tests and to build a database for CFD validation. In the present study, free roll decay tests in calm water with both intact and damaged ships were performed and six degree-of-freedom (6DOF motion responses of intact ship in regular waves were measured. Through the free roll decay tests, the effects of the flooding water on the roll decay motion of a ship were investigated. Through the model tests in regular waves, the database that provides 6DOF motion responses of intact ship was established.

  19. Study and Preliminary Analysis of Test of Aerosol Migration Mechanism

    Institute of Scientific and Technical Information of China (English)

    CHEN; Lin-lin; SUN; Xue-ting; WEI; Yan-song

    2015-01-01

    TAMM(test of aerosol migration mechanism)is one of the important aspects of Studies on Migration Mechanism of the Source Term under Severe Accident,which is a significant research of the National Large Advanced PWR Research Program.The main task researches the

  20. Preliminary Results of Breakwater Round-Head Tests

    DEFF Research Database (Denmark)

    Burcharth, H. F.; Liu, Z.

    1995-01-01

    The rational design diagram for Dolos armour should incorporate both the hydraulic stability and the structural integrity. The previous tests performed by Aalborg University (AU) made available such design diagram for the trunk of Dolos breakwater without superstructures (Burcharth et al. 1992...

  1. The Phillips Laboratory capillary pumped loop test facility

    Science.gov (United States)

    Gluck, Donald F.; Kaylor, Marc C.

    1996-03-01

    An ammonia capillary pumped loop (CPL) test facility has been designed, fabricated, subject to acceptance tests, and assembled at Phillips Laboratory. Its intent is to support a wide range of Air Force programs, bringing CPL technology to flight readiness for operational systems. The facility provides a high degree of modularity and flexibility with several heating and cooling options, and capability for elevation (+/- 15 in.), tilt (+/-60°) and transport length variation. It has a 182 by 44 by 84 inch envelope, an expected heat load capability of 2500 W, and a temperature range of 0 to 50 °C. The evaporator section has two plates with four capillary pumps (CPs) each, with a starter pump on one plate. The CPs are 5/8 in., with TAG aluminum 6063-T6 casing and UHMW polyethylene wicks. The active lengths are 15 and 30 inch with both 10 and 15 micron wicks. The individual CPs have thermal and hydraulic isolation capability, and are removable. The transport section consists of stainless steel lines in a serpentine configuration, a 216 in3 free volume reservoir, and a mechanical pump. The vapor transport line contains a capillary device (which can be bypassed) for vapor blockage during startup. The condenser consists of two separately valved, parallel cold plates each with a downstream noncondensible gas trap. Cooling of up to 1500 W at -50 °C is provided by an FTS Systems chiller using Flourinert FC-72. An enclosure/exhaust system is provided for safety and emergency venting of ammonia. An ammonia charge station performs or supports the functions of proof pressure, flushing with ammonia, purging with gaseous nitrogen, evacuation of all or part of the CPL to 20 microns, and charging. Instrumentation consists of over 116 thermocouples, five of which are internal; one absolute and six differential pressure transducers; eleven watt transducers, and a reservoir load cell. The data acquisition system consists of a temperature scanner, Bernoulli drive, and two Macintosh

  2. Settling velocity of marine microplastic particles: laboratory tests

    Science.gov (United States)

    Isachenko, Igor; Khatmullina, Lilia; Chubarenko, Irina; Stepanova, Natalia

    2016-04-01

    An assessment of the settling velocity of different classes of microplastic particles (microplastic particles is usually outside the Stokes range (Re 105). Even for such transitional regime, the settling velocity of the particles that could be treated as more or less smooth spheres can be predicted with high accuracy by relationships available in publications. This is not the case for the non-spherical particles like fibres or flakes. There are quite a large number of quasi-theoretical or semi-empirical approaches that take into account the shape and roughness of the particles, usually in the applications to transport of natural sediments. Some engineering formulas for the settling velocity are also developed which have simpler structure along with high degree of accuracy on the set of experimental data. For marine microplastic particles, the absence of relationship between the settling velocity and the properties of the particle requires testing on the samples of marine microplastics. Besides small fragments of rigid plastic (granules, microbeads), there are also fibres and thin plastic sheets (flakes) with some degree of flexibility. The applicability of available formulae to thin and/or flexible plastic particles again requires verification by experiments. The set of laboratory experiments on settling of microplastic particles of various shapes and excess densities in homogeneous water is reported. The particles were collected in water column, bottom sediments and on the beaches of the South-Eastern Baltic. The experiments demonstrate not just different regimes of motion but different manner of the sinking of spheres, flakes and fibres. The very definition of the "settling velocity" has a specific meaning for every kind of a particle shape. The results of test measurements are compared with predictions by several published semi-empirical formulae. We conclude that there are several new questions to discuss in this regard: (i) proper definition of the meaning of

  3. Semantic Verbal Fluency test in dementia: Preliminary retrospective analysis

    Directory of Open Access Journals (Sweden)

    Marcos Lopes

    Full Text Available Abstract The Semantic Verbal Fluency (SVF test entails the generation of words from a given category within a pre-set time of 60 seconds. Objectives: To verify whether socio-demographic and clinical data of individuals with dementia correlate with the performance on the SVF test and to ascertain whether differences among the criteria of number of answers, clusters and data spread over the intervals, predict clinical results. Methods: This was a retrospective study of 49 charts of demented patients classified according to the Clinical Dementia Rating (CDR scale. We correlated education, age and gender, as well as CDR and Mini-Mental State Exam (MMSE scores with the number of answers, clustering and switching distributed over four 15-second intervals on the SVF test. Results: The correlation between number of answers and quartiles was weak (r=0.407, p=0.004; r=0.484, p<0.001 but correlation between the number of clusters and responses was strong (r=0.883, p<0.001. The number of items on the SVF was statistically significant with MMSE score (p=0.01 and there was a tendency for significance on the CDR (p=0.06. The results indicated little activity regarding what we propose to call cluster recalling in the two groups. Discussion: The SVF test, using number of items generated, was found to be more effective than classic screening tests in terms of speed and ease of application in patients with CDR 2 and 3.

  4. The National Market for Medicare Clinical Laboratory Testing

    Data.gov (United States)

    U.S. Department of Health & Human Services — Current Medicare payment policy for outpatient laboratory services is outdated. Future reforms, such as competitive bidding, should consider the characteristics of...

  5. Preference Testing as Environmental Enrichment Assessment for Laboratory Mice

    National Research Council Canada - National Science Library

    Navakanit Sachanonta; Waridtha Sa-ngeunreung; Somchai Sa-ing-kaew; Raywadee Butraporn

    2013-01-01

      In the field of biomedical research, a wide variety of environmental enrichment items are available for laboratory mice to fulfill its physiological and behavioral needs which influence the outcome...

  6. The National Market for Medicare Clinical Laboratory Testing

    Data.gov (United States)

    U.S. Department of Health & Human Services — Current Medicare payment policy for outpatient laboratory services is outdated. Future reforms, such as competitive bidding, should consider the characteristics of...

  7. Elusive antimatter formed in laboratory scientists testing nature's deepest secrets

    CERN Multimedia

    Boyd, R S

    2002-01-01

    A team of European physicists reported the creation in a Swiss laboratory of at least 50,000 atoms of antihydrogen, the first time a significant quantity of antimatter has been produced on earth (1 page).

  8. Results of Laboratory Testing of Advanced Power Strips: Preprint

    Energy Technology Data Exchange (ETDEWEB)

    Earle, L.; Sparn, B.

    2012-08-01

    This paper describes the results of a laboratory investigation to evaluate the technical performance of advanced power strip (APS) devices when subjected to a range of home entertainment center and home office usage scenarios.

  9. Laboratory testing improves diagnosis and treatment outcomes in primary health care facilities

    Directory of Open Access Journals (Sweden)

    Jane Y. Carter

    2011-12-01

    Full Text Available Objective: To determine if use of basic laboratory tests improves diagnosis and treatment outcomes in outpatients attending rural primary health care facilities.Setting: Six rural health centres in Kenya.Design: Cross-sectional study to observe change in diagnosis and treatment made by clinical officers after laboratory testing in outpatients attending six rural health centres in Kenya.Subject: The diagnosis and treatment of 1134 patients attending outpatient services in six rural health centres were compared before and after basic laboratory testing. Essential clinical diagnostic equipment and laboratory tests were established at each health centre. Clinical officers and laboratory technicians received on-site refresher training in good diagnostic practices and laboratory procedures before the study began.Results: Laboratory tests were ordered on 704 (62.1% patients. Diagnosis and treatment were changed in 45% of tested patients who returned with laboratory results (21% of all patients attending the clinics. 166 (23.5% patients did not return to the clinician for a final diagnosis and management decision after laboratory testing. Blood slide examination for malaria parasites, wet preparations, urine microscopy and stool microscopy resulted in most changes to diagnosis. There was no significant change in drug costs after laboratory testing. The greatest changes in numbers of recorded diseases following laboratory testing was for intestinal worms (53% and malaria (21%.Conclusion: Effective use of basic laboratory tests at primary health care level significantly improves diagnosis and patient treatment. Use of laboratory testing can be readily incorporated into routine clinical practice. On-site refresher training is an effective means of improving the quality of patient care and communication between clinical and laboratory staff.

  10. Laboratory testing during critical care transport: point-of-care testing in air ambulances.

    Science.gov (United States)

    Di Serio, Francesca; Petronelli, Maria Antonia; Sammartino, Eugenio

    2010-07-01

    Air and ground transport are used for prehospital transport of patients in acute life-threatening situations, and increasingly, critically ill patients undergo interhospital transportation. Results from clinical studies suggest that critical tests performed during the transport of critically ill patients presents a potential opportunity to improve patient care. Our project was to identify, according to the recommendations published at this time, a model of point-of-care testing (POCT) (arterial blood gases analysis and glucose, sodium, potassium, ionized calcium, hematocrit/hemoglobin measurements) in air ambulances. In order to identify the key internal and external factors that are important to achieving our objective, an analysis of the Strengths, Weaknesses, Opportunities, and Threats (SWOT analysis) was incorporated into our planning model prior to starting the project. To allow the entire POCT process (pre-, intra-, and post-analytic steps) to be under the control of the reference laboratory, an experimental model of information technology was applied. Real-time results during transport of critically ill patients must be considered to be an integral part of the patient care process and excellent channels of communication are needed between the intensive care units, emergency medical services and laboratories. With technological and computer advances, POCT during critical care transport will certainly increase in the future: this will be a challenge from a laboratory and clinical context.

  11. Preliminary Results of Testing of Flow Effects on Evaporator Scaling

    Energy Technology Data Exchange (ETDEWEB)

    Hu, M.Z.

    2002-02-15

    This investigation has focused on the effects of fluid flow on solids deposition from solutions that simulate the feed to the 2H evaporator at the Savannah River Site. Literature studies indicate that the fluid flow (or shear) affects particle-particle and particle-surface interactions and thus the phenomena of particle aggregation in solution and particle deposition (i.e., scale formation) onto solid surfaces. Experimental tests were conducted with two configurations: (1) using a rheometer to provide controlled shear conditions and (2) using controlled flow of reactive solution through samples of stainless steel tubing. All tests were conducted at 80 C and at high silicon and aluminum concentrations, 0.133 M each, in solutions containing 4 M sodium hydroxide and 1 A4 each of sodium nitrate and sodium nitrite. Two findings from these experiments are important for consideration in developing approaches for reducing or eliminating evaporator scaling problems: (1) The rheometer tests suggested that for the conditions studied, maximum solids deposition occurs at a moderate shear rate, approximately 12 s{sup -1}. That value is expected to be on the order of shear rates that will occur in various parts of the evaporator system; for instance, a 6 gal/min single-phase liquid flow through the 2-in. lift or gravity drain lines would result in a shear rate of approximately 16 s{sup -1}. These results imply that engineering approaches aimed at reducing deposits through increased mixing would need to generate shear near all surfaces significantly greater than 12 s{sup -1}. However, further testing is needed to set a target value for shear that is applicable to evaporator operation. This is because the measured trend is not statistically significant at the 95% confidence interval due to variability in the results. In addition, testing at higher temperatures and lower concentrations of aluminum and silicon would more accurately represent conditions in the evaporator. Without

  12. Flight Test 4 Preliminary Results: NASA Ames SSI

    Science.gov (United States)

    Isaacson, Doug; Gong, Chester; Reardon, Scott; Santiago, Confesor

    2016-01-01

    Realization of the expected proliferation of Unmanned Aircraft System (UAS) operations in the National Airspace System (NAS) depends on the development and validation of performance standards for UAS Detect and Avoid (DAA) Systems. The RTCA Special Committee 228 is charged with leading the development of draft Minimum Operational Performance Standards (MOPS) for UAS DAA Systems. NASA, as a participating member of RTCA SC-228 is committed to supporting the development and validation of draft requirements as well as the safety substantiation and end-to-end assessment of DAA system performance. The Unmanned Aircraft System (UAS) Integration into the National Airspace System (NAS) Project conducted flight test program, referred to as Flight Test 4, at Armstrong Flight Research Center from April -June 2016. Part of the test flights were dedicated to the NASA Ames-developed Detect and Avoid (DAA) System referred to as JADEM (Java Architecture for DAA Extensibility and Modeling). The encounter scenarios, which involved NASA's Ikhana UAS and a manned intruder aircraft, were designed to collect data on DAA system performance in real-world conditions and uncertainties with four different surveillance sensor systems. Flight test 4 has four objectives: (1) validate DAA requirements in stressing cases that drive MOPS requirements, including: high-speed cooperative intruder, low-speed non-cooperative intruder, high vertical closure rate encounter, and Mode CS-only intruder (i.e. without ADS-B), (2) validate TCASDAA alerting and guidance interoperability concept in the presence of realistic sensor, tracking and navigational errors and in multiple-intruder encounters against both cooperative and non-cooperative intruders, (3) validate Well Clear Recovery guidance in the presence of realistic sensor, tracking and navigational errors, and (4) validate DAA alerting and guidance requirements in the presence of realistic sensor, tracking and navigational errors. The results will be

  13. Summary report - development of laboratory tests and the stress- strain behaviour of Olkiluoto mica gneiss

    Energy Technology Data Exchange (ETDEWEB)

    Hakala, M.; Heikkilae, E. [Helsinki Univ. of Technology, Espoo (Finland). Lab. of Rock Engineering

    1997-05-01

    This work summarizes the project aimed at developing and qualifying a suitable combination of laboratory tests to establish a statistically reliable stress-strain behaviour of the main rock types at Posiva Oy`s detailed investigation sites for disposal of spent nuclear fuel. The work includes literature study of stress-strain behaviour of brittle rock, development and qualification of laboratory tests, suggested test procedures and interpretation methods and finally testing of Olkiluoto mica gneiss. The Olkiluoto study includes over 130 loading tests. Besides the commonly used laboratory tests, direct tensile tests, damage controlled tests and acoustic emission measurements were also carried out. (orig.) (54 refs.).

  14. Biological cycle and preliminary data on vectorial competence of Triatoma boliviana in laboratory conditions.

    Science.gov (United States)

    Durán, Pamela; Siñani, Edda; Depickère, Stéphanie

    2014-12-01

    With more than 140 potential vectors of Chagas disease, it is important to better know the biology and especially the vectorial capacity of the triatomine species which live in the surroundings of human dwellings. In Bolivia where 17 triatomine species are reported, the principal vector is Triatoma infestans. In some valleys of the department of La Paz where T. infestans is not present, a new species (Triatoma boliviana) was described in 2007. This species lives in a sylvatic environment not far away from the dwellings, and occasionally some individuals are found inside the houses. This study was carried out to describe the biological cycle of T. boliviana and to determine its vectorial competence. The development of a cohort of 95 nymphs of first instar (N1) was followed through nymphal instars and adult stage until death in laboratory (22°C). They were fed twice a week on an immobilized mouse. The median egg-to-adult development time was 8.4 months. The mortality by nymphal instar was lower than 7% except for N1 (67%) and N5 (18%). All nymph instars needed at least two feedings to molt (until six feedings for N5). The differentiation of a nymph into a female or a male could not be detected until the fifth instar for which the food intake was greater for a nymph developing into a female. Adults fed about once a week. The adult life span was around 400 days. The fecundity was 4.2 eggs/female/week, with a hatching rate of 50% and a hatching time of 39 days. In the same conditions, T. infestans showed a similar fecundity but a greater hatching rate and hatching time. A trial for rearing the adults at a higher temperature (26°C) showed a drastic fall in the fecundity and in the hatching rate. The vectorial competence was analyzed for fifth instars and adults by three parameters: the ability to feed on human beings, the capacity to be infected by T. cruzi and the postfeeding defecation delay. Results showed a relatively high vectorial competence: (1) insects fed

  15. Preliminary Conceptual Design Report for the FACET-II Project at SLAC National Accelerator Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Hogan, Mark [SLAC National Accelerator Lab., Menlo Park, CA (United States)

    2016-04-22

    Plasma wakefield acceleration has the potential to dramatically shrink the size and cost of particle accelerators. Research at the SLAC National Accelerator Laboratory has demonstrated that plasmas can provide 1,000 times the acceleration in a given distance compared with current technologies. Developing revolutionary and more efficient acceleration techniques that allow for an affordable high-energy collider is the focus of FACET, a National User Facility at SLAC. The existing FACET National User Facility uses part of SLAC’s two-mile-long linear accelerator to generate high-density beams of electrons and positrons. FACET-II is a new test facility to develop advanced acceleration and coherent radiation techniques with high-energy electron and positron beams. It is the only facility in the world with high energy positron beams. FACET-II provides a major upgrade over current FACET capabilities and the breadth of the potential research program makes it truly unique. It will synergistically pursue accelerator science that is vital to the future of both advanced acceleration techniques for High Energy Physics, ultra-high brightness beams for Basic Energy Science, and novel radiation sources for a wide variety of applications. The design parameters for FACET-II are set by the requirements of the plasma wakefield experimental program. To drive the plasma wakefield requires a high peak current, in excess of 10kA. To reach this peak current, the electron and positron design bunch size is 10μ by 10μ transversely with a bunch length of 10μ. This is more than 200 times better than what has been achieved at the existing FACET. The beam energy is 10 GeV, set by the Linac length available and the repetition rate is up to 30 Hz. The FACET-II project is scheduled to be constructed in three major stages. Components of the project discussed in detail include the following: electron injector, bunch compressors and linac, the positron system, the Sector 20 sailboat and W chicanes

  16. Development of New, Low-Head Hydropower Turbine - Modeling & Laboratory Test DE-EE0005426

    Energy Technology Data Exchange (ETDEWEB)

    Krouse, Wayne [Hydro Green Energy, Westmont, IL (United States)

    2014-12-05

    Hydro Green Energy, LLC (HGE) will complete the design, fabrication and laboratory testing of a scaled, vertically stackable, low-head hydropower turbine called the Modular Bulb Turbine (MBT). HGE will also complete a summary report that includes the laboratory testing results and analysis of the tests. Project Goals: Design, model and test modular bulb turbine for installation in numerous HGE low-head hydropower projects at non-powered USACE dams. Project Results: The sub-scale prototype was tested successfully at a leading US hydraulic laboratory. Laboratory data results agreed well with predicted results from numerical modeling.

  17. Preliminary operational results of the industrial process heat field tests

    Energy Technology Data Exchange (ETDEWEB)

    Kutscher, C.; Davenport, R.

    1980-04-01

    There are currently six DOE-funded solar industrial process heat (IPH) field tests which have been operational for one year or longer. These are all low temperature first generation projects which supply heat at temperatures below 100/sup 0/C - three hot water and three hot air. During the 1979 calendar year, personnel from the Solar Energy Research Institute (SERI) visited all of these sites; the performance and cost results obtained for each project and the operational problems encountered at each site are discussed.

  18. PEP Support Laboratory Leaching and Permeate Stability Tests

    Energy Technology Data Exchange (ETDEWEB)

    Russell, Renee L.; Peterson, Reid A.; Rinehart, Donald E.; Buchmiller, William C.

    2009-09-25

    Pacific Northwest National Laboratory (PNNL) has been tasked by Bechtel National Inc. (BNI) on the River Protection Project-Hanford Tank Waste Treatment and Immobilization Plant (RPP-WTP) project to perform research and development activities to resolve technical issues identified for the Pretreatment Facility (PTF). The Pretreatment Engineering Platform (PEP) was designed, constructed, and operated as part of a plan to respond to issue M12, "Undemonstrated Leaching Processes," of the External Flowsheet Review Team (EFRT) issue response plan.( ) The PEP is a 1/4.5-scale test platform designed to simulate the WTP pretreatment caustic leaching, oxidative leaching, ultrafiltration solids concentration, and slurry washing processes. The PEP replicates the WTP leaching processes using prototypic equipment and control strategies. A simplified flow diagram of the PEP system is shown in Figure 1.1. Two operating scenarios are currently being evaluated for the ultrafiltration process (UFP) and leaching operations. The first scenario has caustic leaching performed in the UFP-2 ultrafiltration feed vessels (i.e., vessel UFP-VSL-T02A in the PEP and vessels UFP-VSL-00002A and B in the WTP PTF). The second scenario has caustic leaching conducted in the UFP-1 ultrafiltration feed preparation vessels (i.e., vessels UFP-VSL-T01A and B in the PEP and vessels UFP-VSL-00001A and B in the WTP PTF). In both scenarios, 19-M sodium hydroxide solution (NaOH, caustic) is added to the waste slurry in the vessels to leach solid aluminum compounds (e.g., gibbsite, boehmite). Caustic addition is followed by a heating step that uses direct injection of steam to accelerate the leach process. Following the caustic leach, the vessel contents are cooled using vessel cooling jackets and/or external heat exchangers. The main difference between the two scenarios is that for leaching in UFP-VSL-T01A and B, the 19-M NaOH is added to un-concentrated waste slurry (3 to 8 wt% solids), while for leaching in

  19. Laboratory Testing of Magnetic Tracers for Soil Erosion Measurement*1

    Institute of Scientific and Technical Information of China (English)

    HU Guo-Qing; DONG Yuan-Jie; WANG Hui; QIU Xian-Kui; WANG Yan-Hua

    2011-01-01

    Soil erosion, which includes soil detachment, transport, and deposition, is one of the important dynamic land surface processes. The magnetic tracer method is a useful method for studying soil erosion processes. In this study, five types of magnetic tracers were made with fine soil, fly ash, cement, bentonite, and magnetic powder (reduced iron powder) using the method of disk granulation. The tracers were uniformly mixed with soil and tested in the laboratory using simulated rainfall and inflow experiments to simulate the interrill and rill components of soil erosion, in order to select one or more tracers which could be used to study detachment and deposition by the erosive forces of raindrops and surface flow of water on a slope. The results showed that the five types of magnetic tracers with high magnetic susceptibility and a wide range of sizes had a range of 0.99-1.29 gcm-s in bulk density. In the interrill and rill experiments, the tracers FC1 and FC2 which consisted of fly ash and cement at ratios of 1:1 and 2:1, respectively, were transported in phase with soil particles since the magnetic susceptibility of sediment approximated that of the soil which was uneroded and the slopes of the regression equations between the detachment of sediment and magnetic tracers FC1 and FC2 were very close to the expected value of 20, which was the original soil/tracer ratio. The detachment and deposition on slopes could be accurately reflected by the magnetic susceptibility differences. The change in magnetic susceptibility depended on whether deposition or detachment occurred. However, the tracer FS which consisted of fine soil and the tracers FB1 and FB2 which consisted of fly ash and bentonite at ratios of 1:1 and 2:1, respectively, were all unsuitable for soil erosion study since there was no consistent relationship between sediment and tracer detachment for increasing amounts of runoff. Therefore, the tracers FC1 and FC2 could be used to study soil erosion by water.

  20. Preliminary results of the round-robin testing of F82H

    Energy Technology Data Exchange (ETDEWEB)

    Shiba, K.; Yamanouchi, N.; Tohyama, A.

    1996-10-01

    Preliminary results of metallurgical, physical and mechanical properties of low activation ferritic steel F82H (IEA heat) were obtained in the round-robin test in Japan. The properties of IEA heat F82H were almost the same as the original F82H.

  1. Preliminary results of a proficiency testing of industrial CT scanners using small polymer items

    DEFF Research Database (Denmark)

    Angel, Jais Andreas Breusch; Cantatore, Angela; De Chiffre, Leonardo

    2012-01-01

    This work presents preliminary results concerning a proficiency testing for intercomparison of industrial CT scanners. Two audit items, similar to common industrial parts, were selected for circulation. The two items were a single polymer complex geometry part and a simple geometry item made of two...

  2. Preliminary Investigation of the 1991 Medical College Admission Test Factor Structure.

    Science.gov (United States)

    Li, Weichang; Mitchell, Karen J.

    A substantially revised Medical College Admission Test (MCAT) was introduced in spring 1991. The new examination is designed to assess critical thinking skills, basic concepts and problem solving facility in science, and writing skills. This paper reports preliminary findings on the factor structure of the revised MCAT, which consists of four…

  3. Sizing and preliminary hardware testing of solar powered UAV

    Directory of Open Access Journals (Sweden)

    S. Jashnani

    2013-12-01

    Full Text Available Integrating solar energy into modern aircraft technology has been a topic of interest and has received a lot of attention from researchers over the last two decades. A few among the many potential applications of this technology are the possibility of continuous self sustained flight for purposes such as information relay, surveillance and monitoring. This paper discusses the altitude and payload mass, as independent parameters, and their influence on the size and design of the aircraft. To estimate available solar power, two different models have been presented; one for low altitudes and the other for high altitudes. An engineering ground model was built to simulate the power and propulsion system over 24 h of continuous operation. The paper presents data from tests performed till date and lessons learnt while dealing with the construction of the engineering ground model as well as changes that can be made to improve the design.

  4. Preliminary laboratory evaluation of iron-bearing reactive media for pesticide water treatment

    Science.gov (United States)

    Agricultural pesticides are often found in ground and surface waters, and if present in high enough concentrations, create risks to human and ecological health. Filter treatment systems can potentially remove pesticides from water. Therefore, a laboratory investigation was initiated to assess the wa...

  5. Characterizing the Experimental Procedure in Science Laboratories: A Preliminary Step towards Students Experimental Design

    Science.gov (United States)

    Girault, Isabelle; d'Ham, Cedric; Ney, Muriel; Sanchez, Eric; Wajeman, Claire

    2012-01-01

    Many studies have stressed students' lack of understanding of experiments in laboratories. Some researchers suggest that if students design all or parts of entire experiment, as part of an inquiry-based approach, it would overcome certain difficulties. It requires that a procedure be written for experimental design. The aim of this paper is to…

  6. Genetic antimicrobial susceptibility testing in Gram-negative sepsis - impact on time to results in a routine laboratory.

    Science.gov (United States)

    Kommedal, Øyvind; Aasen, Johanne Lind; Lindemann, Paul Christoffer

    2016-07-01

    Diagnostic testing of positive blood cultures is among the most critical tasks performed by clinical microbiology laboratories, and the total analysis time from sampling to results should be kept as short as possible. By providing identification of pelleted bacteria directly from positive blood-cultures, MALDI-TOF MS opens for relatively low-complex species-adjusted genetic susceptibility testing from the same bacterial pellet. In our lab routine, we prospectively evaluated a rapid in-house real-time PCR targeting the most common aminoglycoside and cephalosporin resistance genes in Escherichia coli and Klebsiella pneumoniae and measured time to preliminary susceptibility reporting for 138 samples. The results were compared to direct phenotypic susceptibility testing with interpretation after 6 h and overnight incubation respectively. Results from the genetic susceptibility testing were available for 69.5% (96/138) of the positive blood cultures within 24 h after sample collection. No phenotypic susceptibility results were available at this time. Compared to overnight direct susceptibility testing, the average time from sample collection to preliminary susceptibility reporting was reduced with 43%, from 45 h and 5 min to 25 h and 44 min, providing an earlier adjustment of antimicrobial therapy for 12 patients. Minor logistic adjustments have the potential to save yet another 4 h.

  7. Development and Challenge of HIV/AIDS Testing Laboratory Network and Quality Assurance System in China

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    This paper describes the development and challenge of HIV/AIDS testing laboratory network and quality assurance system in China. At present, the HIV/AIDS testing laboratories includes three classes, the National AIDS Reference Laboratory, HIV/AIDS confirmatory laboratories and HIV/AIDS screening laboratories. All of them are accredited by the health authorities, and each class of laboratories take charge of their function strictly according to the "National Management of HIV/AIDS Detection (2006)". A complete quality assurance and quality control system for HIV/AIDS testing has been developed, which includes technical training, strict laboratory monitoring and approval,examination or proficiency testing on HIV/AIDS detection, and quality evaluation and supervision of HIV/AIDS diagnostic kits. Besides conduct the routine anti-HIV antibody test, more and more laboratories began to conduct other tests, such as CD4+ T lymphocyte cell counting, HIV viral load, HIV DNA PCR, genotyping, drug resistance, and HIV-1 recent infection test. The primary challenges faced by the HIV/AIDS testing laboratory network are in the areas of laboratory management and quality control. For example, the provincial PT program is inefficient, the internal quality control is conducted perfunctorily, personnel training can not met the needs of the workplace, which need to be improved.

  8. IMAGE Project: Results of Laboratory Tests on Tracers for Supercritical Conditions.

    Science.gov (United States)

    Brandvoll, Øyvind; Opsahl Viig, Sissel; Nardini, Isabella; Muller, Jiri

    2016-04-01

    The use of tracers is a well-established technique for monitoring dynamic behaviour of water and gas through a reservoir. In geothermal reservoirs special challenges are encountered due to high temperatures and pressures. In this work, tracer candidates for monitoring water at supercritical conditions (temperature > 374°C, pressure ca 218 bar), are tested in laboratory experiments. Testing of tracers at supercritical water conditions requires experimental set-ups which tolerate harsh conditions with respect to high temperature and pressure. In addition stringent HES (health, environment and safety) factors have to be taken into consideration when designing and performing the experiments. The setup constructed in this project consists of a pressure vessel, high pressure pump, instrumentation for pressure and temperature control and instrumentation required for accurate sampling of tracers. In order to achieve accurate results, a special focus has been paid to the development of the tracer sampling technique. Perfluorinated cyclic hydrocarbons (PFCs) have been selected as tracer candidates. This group of compounds is today commonly used as gas tracers in oil reservoirs. According to the literature they are stable at temperatures up to 400°C. To start with, five PFCs have been tested for thermal stability in static experiments at 375°C and 108 bar in the experimental setup described above. The tracer candidates will be further tested for several months at the relevant conditions. Preliminary results indicate that some of the PFC compounds show stability after three months. However, in order to arrive at conclusive results, the experiments have to be repeated over a longer period and paying special attention to more accurate sampling procedures.

  9. Laboratory and clinical tests of a prototype pressure sensor for clincial assessment of prosthetic socket fit.

    Science.gov (United States)

    Polliack, A A; Craig, D D; Sieh, R C; Landsberger, S; Mcneal, D R

    2002-04-01

    Lower limb prosthetic socket fabrication is a highly refined process relying on the prosthetist's skill and experience. Despite their best efforts, patients often return with complications. Additionally, clinical application of technological advances for the quantification of biomechanical factors at the socket interface has not changed in practice. Measuring pressure levels at the stump/socket interface could provide valuable information in the process of prosthetic socket fabrication, fit and modification. This paper presents findings on the performance of a prototype capacitance pressure sensor designed for prosthetic socket use. Bench tests using compressed air were performed to measure accuracy, hysteresis and drift responses in both a flatbed chamber and a custom-modified pressure vessel. For the contoured testing, the sensors were placed on nine sites on a positive trans-tibial stump mould and enveloped with a silicone liner. Additionally, a preliminary clinical evaluation was performed with two trans-tibial amputee subjects at the nine sites during normal ambulation. Bench test results showed that the prototype capacitance sensor performed well in all categories, exhibiting a 2.42% (flatbed) and 9.96% (contoured) accuracy error, a 12.93% (flatbed) and 12.95% (contoured) hysteresis error, and a 4.40% (flatbed) and 6.20% (contoured) drift error. The clinical study showed that after three hours of continual use, no noticeable sensor drift occurred between pre and post-test calibration values. The results from this study were encouraging and the authors hope to conduct further laboratory and clinical trials to assess the influence of shear force and dynamic loading on sensor response.

  10. 10 CFR 707.12 - Specimen collection, handling and laboratory analysis for drug testing.

    Science.gov (United States)

    2010-01-01

    ... drug testing. 707.12 Section 707.12 Energy DEPARTMENT OF ENERGY WORKPLACE SUBSTANCE ABUSE PROGRAMS AT DOE SITES Procedures § 707.12 Specimen collection, handling and laboratory analysis for drug testing... collection to final disposition of specimens, and testing laboratories shall use appropriate cutoff levels in...

  11. 19 CFR 151.73 - Importer's request for commercial laboratory test.

    Science.gov (United States)

    2010-04-01

    ... 19 Customs Duties 2 2010-04-01 2010-04-01 false Importer's request for commercial laboratory test... Hair § 151.73 Importer's request for commercial laboratory test. (a) Conditions for commercial test. If the importer is dissatisfied with the results of a retest made in accordance with § 151.71(c), he...

  12. King County Metro Transit: Allison Hybrid Electric Transit Bus Laboratory Testing

    Energy Technology Data Exchange (ETDEWEB)

    Hayes, R. R.; Williams, A.; Ireland, J.; Walkowicz, K.

    2006-09-01

    Paper summarizes chassis dynamometer testing of two 60-foot articulated transit buses, one conventional and one hybrid, at NREL's ReFUEL Laboratory. It includes experimental setup, test procedures, and results from vehicle testing performed at the NREL ReFUEL laboratory.

  13. 30 CFR 14.21 - Laboratory-scale flame test apparatus.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Laboratory-scale flame test apparatus. 14.21 Section 14.21 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR TESTING... Technical Requirements § 14.21 Laboratory-scale flame test apparatus. The principal parts of the...

  14. 40 CFR Appendix II to Part 1054 - Duty Cycles for Laboratory Testing

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 32 2010-07-01 2010-07-01 false Duty Cycles for Laboratory Testing II Appendix II to Part 1054 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR.... 1054, App. II Appendix II to Part 1054—Duty Cycles for Laboratory Testing (a) Test handheld...

  15. Preliminary Scaling Estimate for Select Small Scale Mixing Demonstration Tests

    Energy Technology Data Exchange (ETDEWEB)

    Wells, Beric E.; Fort, James A.; Gauglitz, Phillip A.; Rector, David R.; Schonewill, Philip P.

    2013-09-12

    The Hanford Site double-shell tank (DST) system provides the staging location for waste that will be transferred to the Hanford Tank Waste Treatment and Immobilization Plant (WTP). Specific WTP acceptance criteria for waste feed delivery describe the physical and chemical characteristics of the waste that must be met before the waste is transferred from the DSTs to the WTP. One of the more challenging requirements relates to the sampling and characterization of the undissolved solids (UDS) in a waste feed DST because the waste contains solid particles that settle and their concentration and relative proportion can change during the transfer of the waste in individual batches. A key uncertainty in the waste feed delivery system is the potential variation in UDS transferred in individual batches in comparison to an initial sample used for evaluating the acceptance criteria. To address this uncertainty, a number of small-scale mixing tests have been conducted as part of Washington River Protection Solutions’ Small Scale Mixing Demonstration (SSMD) project to determine the performance of the DST mixing and sampling systems.

  16. Los Alamos National Laboratory corregated metal pipe saw facility preliminary safety analysis report. Volume I

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1990-09-19

    This Preliminary Safety Analysis Report addresses site assessment, facility design and construction, and design operation of the processing systems in the Corrugated Metal Pipe Saw Facility with respect to normal and abnormal conditions. Potential hazards are identified, credible accidents relative to the operation of the facility and the process systems are analyzed, and the consequences of postulated accidents are presented. The risk associated with normal operations, abnormal operations, and natural phenomena are analyzed. The accident analysis presented shows that the impact of the facility will be acceptable for all foreseeable normal and abnormal conditions of operation. Specifically, under normal conditions the facility will have impacts within the limits posted by applicable DOE guidelines, and in accident conditions the facility will similarly meet or exceed the requirements of all applicable standards. 16 figs., 6 tabs.

  17. Laboratory test of source encapsulation for decreasing PCB concentrations

    DEFF Research Database (Denmark)

    Kolarik, Barbara; Andersen, Helle Vibeke; Markowicz, Pawel

    2016-01-01

    This study investigates the effect of encapsulation of tertiary PCB sources with PERMASORB™ Adsorber Wallpaper and the surface emissions trap (cTrap) on indoor air concentration of PCBs and on the PCB content in the source. The 40 weeks long laboratory investigation shows reduction of the air...

  18. Test-beam and laboratory characterisation of the TORCH prototype detector

    CERN Document Server

    Ros, A; Castillo-Garcia, L; Conneely, T; Cussans, D; Foehl, K; Forty, R; Frei, C; Gao, R; Gys, T; Harnew, N; Milnes, J; Piedigrossi, D; Rademacker, J; Van Dijk, M

    2016-01-01

    The TORCH time-of-flight (TOF) detector is being developed to provide particle identification up to a momentum of 10 GeV/c over a flight distance of 10 m. It has a DIRC-like construction with View the MathML source10mm thick synthetic amorphous fused-silica plates as a Cherenkov radiator. Photons propagate by total internal reflection to the plate periphery where they are focused onto an array of customised position-sensitive micro-channel plate (MCP) detectors. The goal is to achieve a 15 ps time-of-flight resolution per incident particle by combining arrival times from multiple photons. The MCPs have pixels of effective size 0.4 mm×6.6 mm2 in the vertical and horizontal directions, respectively, by incorporating a novel charge-sharing technique to improve the spatial resolution to better than the pitch of the readout anodes. Prototype photon detectors and readout electronics have been tested and calibrated in the laboratory. Preliminary results from testbeam measurements of a prototype TORCH detector are a...

  19. Test-beam and laboratory characterisation of the TORCH prototype detector

    CERN Document Server

    Ros, A; Castillo-Garcia, L; Conneely, T; Cussans, D; Foehl, K; Forty, R; Frei, C; Gao, R; Gys, T; Harnew, N; Milnes, J; Piedigrossi, D; Rademacker, J; Van Dijk, M

    2016-01-01

    The TORCH time-of-flight (TOF) detector is being developed to provide particle identification up to a momentum of 10 GeV/c over a flight distance of 10 m. It has a DIRC-like construction with View the MathML source10mm thick synthetic amorphous fused-silica plates as a Cherenkov radiator. Photons propagate by total internal reflection to the plate periphery where they are focused onto an array of customised position-sensitive micro-channel plate (MCP) detectors. The goal is to achieve a 15 ps time-of-flight resolution per incident particle by combining arrival times from multiple photons. The MCPs have pixels of effective size 0.4 mm×6.6 mm2 in the vertical and horizontal directions, respectively, by incorporating a novel charge-sharing technique to improve the spatial resolution to better than the pitch of the readout anodes. Prototype photon detectors and readout electronics have been tested and calibrated in the laboratory. Preliminary results from testbeam measurements of a prototype TORCH detector are a...

  20. 78 FR 59946 - Current List of Laboratories and Instrumented Initial Testing Facilities Which Meet Minimum...

    Science.gov (United States)

    2013-09-30

    ... Public Law 100-71. The ``Mandatory Guidelines for Federal Workplace Drug Testing Programs,'' as amended... Partnership, 245 Pall Mall Street, London, ONT, Canada N6A 1P4, 519-679-1630. Laboratory Corporation of...: Centinela Hospital Airport Toxicology Laboratory). Pathology Associates Medical Laboratories, 110 West Cliff...

  1. Preliminary Assessment of the Mars Science Laboratory Entry, Descent, and Landing Simulation

    Science.gov (United States)

    Way, David W.

    2013-01-01

    On August 5, 2012, the Mars Science Laboratory rover, Curiosity, successfully landed inside Gale Crater. This landing was only the seventh successful landing and fourth rover to be delivered to Mars. Weighing nearly one metric ton, Curiosity is the largest and most complex rover ever sent to investigate another planet. Safely landing such a large payload required an innovative Entry, Descent, and Landing system, which included the first guided entry at Mars, the largest supersonic parachute ever flown at Mars, and a novel and untested Sky Crane landing system. A complete, end-to-end, six degree-of-freedom, multibody computer simulation of the Mars Science Laboratory Entry, Descent, and Landing sequence was developed at the NASA Langley Research Center. In-flight data gathered during the successful landing is compared to pre-flight statistical distributions, predicted by the simulation. These comparisons provide insight into both the accuracy of the simulation and the overall performance of the vehicle.

  2. A preliminary study of breast cancer diagnosis using laboratory based small angle x-ray scattering

    Science.gov (United States)

    Round, A. R.; Wilkinson, S. J.; Hall, C. J.; Rogers, K. D.; Glatter, O.; Wess, T.; Ellis, I. O.

    2005-09-01

    Breast tissue collected from tumour samples and normal tissue from bi-lateral mastectomy procedures were examined using small angle x-ray scattering. Previous work has indicated that breast tissue disease diagnosis could be performed using small angle x-ray scattering (SAXS) from a synchrotron radiation source. The technique would be more useful to health services if it could be made to work using a conventional x-ray source. Consistent and reliable differences in x-ray scatter distributions were observed between samples from normal and tumour tissue samples using the laboratory based 'SAXSess' system. Albeit from a small number of samples, a sensitivity of 100% was obtained. This result encourages us to pursue the implementation of SAXS as a laboratory based diagnosis technique.

  3. A preliminary study of breast cancer diagnosis using laboratory based small angle x-ray scattering

    Energy Technology Data Exchange (ETDEWEB)

    Round, A R [Daresbury Laboratories, Warrington, WA4 4AD (United Kingdom); Wilkinson, S J [Daresbury Laboratories, Warrington, WA4 4AD (United Kingdom); Hall, C J [Daresbury Laboratories, Warrington, WA4 4AD (United Kingdom); Rogers, K D [Department of Materials and Medical Sciences, Cranfield University, Swindon, SN6 8LA (United Kingdom); Glatter, O [Department of Chemistry, University of Graz (Austria); Wess, T [School of Optometry and Vision Sciences, Cardiff University, Cardiff CF10 3NB, Wales (United Kingdom); Ellis, I O [Nottingham City Hospital, Nottingham (United Kingdom)

    2005-09-07

    Breast tissue collected from tumour samples and normal tissue from bi-lateral mastectomy procedures were examined using small angle x-ray scattering. Previous work has indicated that breast tissue disease diagnosis could be performed using small angle x-ray scattering (SAXS) from a synchrotron radiation source. The technique would be more useful to health services if it could be made to work using a conventional x-ray source. Consistent and reliable differences in x-ray scatter distributions were observed between samples from normal and tumour tissue samples using the laboratory based 'SAXSess' system. Albeit from a small number of samples, a sensitivity of 100% was obtained. This result encourages us to pursue the implementation of SAXS as a laboratory based diagnosis technique.

  4. Preliminary Failure Modes and Effects Analysis of the US DCLL Test Blanket Module

    Energy Technology Data Exchange (ETDEWEB)

    Lee C. Cadwallader

    2007-08-01

    This report presents the results of a preliminary failure modes and effects analysis (FMEA) of a small tritium-breeding test blanket module design for the International Thermonuclear Experimental Reactor. The FMEA was quantified with “generic” component failure rate data, and the failure events are binned into postulated initiating event families and frequency categories for safety assessment. An appendix to this report contains repair time data to support an occupational radiation exposure assessment for test blanket module maintenance.

  5. Preliminary Failure Modes and Effects Analysis of the US DCLL Test Blanket Module

    Energy Technology Data Exchange (ETDEWEB)

    Lee C. Cadwallader

    2010-06-01

    This report presents the results of a preliminary failure modes and effects analysis (FMEA) of a small tritium-breeding test blanket module design for the International Thermonuclear Experimental Reactor. The FMEA was quantified with “generic” component failure rate data, and the failure events are binned into postulated initiating event families and frequency categories for safety assessment. An appendix to this report contains repair time data to support an occupational radiation exposure assessment for test blanket module maintenance.

  6. Determination of basic friction angle using various laboratory tests.

    Science.gov (United States)

    Jang, Bo-An

    2016-04-01

    The basic friction angle of rock is an important factor of joint shear strength and is included within most shear strength criteria. It can be measured by direct shear test, triaxial compression test and tilt test. Tilt test is mostly used because it is the simplest method. However, basic friction angles measured using tilt test for same rock type or for one sample are widely distributed and often do not show normal distribution. In this research, the basic friction angles for the Hangdeung granite form Korea and Berea sandstone from USA are measured accurately using direct shear test and triaxial compression test. Then basic friction angles are again measured using tilt tests with various conditions and are compared with those measured using direct shear test and triaxial compression test to determine the optimum condition of tilt test. Three types of sliding planes, such as planes cut by saw and planes polished by #100 and #600 grinding powders, are prepared. When planes are polished by #100 grinding powder, the basic friction angles measured using direct shear test and triaxial compression test are very consistent and show narrow ranges. However, basic friction angles show wide ranges when planes are cut by saw and are polished by #600 grinding powder. The basic friction angle measured using tilt test are very close to those measured using direct shear test and triaxial compression test when plane is polished by #100 grinding powder. When planes are cut by saw and are polished by #600 grinding powder, basic friction angles measured using tilt test are slightly different. This indicates that tilt test with plane polished by #100 grinding powder can yield an accurate basic friction angle. In addition, the accurate values are obtained not only when planes are polished again after 10 times of tilt test, but values are averaged by more 30 times of tests.

  7. The preliminary results of fast neutron flux measurements in the DULB laboratory at Baksan

    OpenAIRE

    2000-01-01

    One of the main sources of a background in underground physics experiments (such as the investigation of solar neutrino flux, neutrino oscillations, neutrinoless double beta decay, and the search for annual and daily Cold Dark Matter particle flux modulation) are fast neutrons originating from the surrounding rocks. The measurements of fast neutron flux in the new DULB Laboratory situated at a depth of 4900 m w.e. in the Baksan Neutrino Observatory have been performed. The relative neutron sh...

  8. The rapid plasma reagin test cannot replace the venereal disease research laboratory test for neurosyphilis diagnosis.

    Science.gov (United States)

    Marra, Christina M; Tantalo, Lauren C; Maxwell, Clare L; Ho, Emily L; Sahi, Sharon K; Jones, Trudy

    2012-06-01

    The cerebrospinal fluid (CSF) Venereal Disease Research Laboratory (VDRL) test is a mainstay for neurosyphilis diagnosis, but it lacks diagnostic sensitivity and is logistically complicated. The rapid plasma reagin (RPR) test is easier to perform, but its appropriateness for use on CSF is controversial. RPR reactivity was determined for CSF from 149 individuals with syphilis using 2 methods. The CSF-RPR was performed according to the method for serum. The CSF-RPR-V was performed using the method recommended for the CSF-VDRL. Laboratory-defined neurosyphilis included reactive CSF-fluorescent treponemal antibody absorption test and CSF white blood cells >20/uL. Symptomatic neurosyphilis was defined as vision loss or hearing loss. CSF-VDRL was reactive in 45 (30.2%) patients. Of these, 29 (64.4%) were CSF-RPR reactive and 37 (82.2%) were CSF-RPR-V reactive. There were no instances where the CSF-VDRL was nonreactive but the CSF-RPR or CSF-RPR-V was reactive. Among the 28 samples that were reactive in all 3 tests, CSF-VDRL titers (median [IQR], 1:4 [1:4-1:16]) were significantly higher than CSF-RPR (1:2 [1:1-1:4], P = 0.0002) and CSF-RPR-V titers (1:4 [1:2-1:8], P = 0.01). The CSF RPR and the CSF-RPR-V tests had lower sensitivities than the CSF-VDRL: 56.4% and 59.0% versus 71.8% for laboratory-diagnosed neurosyphilis and 51.5% and 57.6% versus 66.7% for symptomatic neurosyphilis. Compared with the CSF-VDRL, the CSF-RPR has a high false-negative rate, thus not improving upon this known limitation of the CSF-VDRL for neurosyphilis diagnosis. Adapting the RPR procedure to mimic the CSF-VDRL decreased, but did not eliminate, the number of false negatives and did not avoid all the logistical complications of the CSF-VDRL.

  9. Laboratory test and acoustic analysis of cabin treatment for propfan test assessment aircraft

    Science.gov (United States)

    Kuntz, H. L.; Gatineau, R. J.

    1991-01-01

    An aircraft cabin acoustic enclosure, built in support of the Propfan Test Assessment (PTA) program, is described. Helmholtz resonators were attached to the cabin trim panels to increase the sidewall transmission loss (TL). Resonators (448) were located between the trim panels and fuselage shell. In addition, 152 resonators were placed between the enclosure and aircraft floors. The 600 resonators were each tuned to a 235 Hz resonance frequency. After flight testing on the PTA aircraft, the enclosure was tested in the Kelly Johnson R and D Center Acoustics Lab. Laboratory noise reduction (NR) test results are discussed. The enclosure was placed in a Gulfstream 2 fuselage section. Broadband (138 dB overall SPL) and tonal (149 dB overall SPL) excitations were used in the lab. Tonal excitation simulated the propfan flight test excitation. The fundamental tone was stepped in 2 Hz intervals from 225 through 245 Hz. The resonators increase the NR of the cabin walls around the resonance frequency of the resonator array. The effects of flanking, sidewall absorption, cabin adsorption, resonator loading of trim panels, and panel vibrations are presented. Increases in NR of up to 11 dB were measured.

  10. Materials and Nondestructive Evaluation Laboratoriers: User Test Planning Guide

    Science.gov (United States)

    Schaschl, Leslie

    2011-01-01

    The Materials and Nondestructive Evaluation Laboratory process, milestones and inputs are unknowns to first-time users. The Materials and Nondestructive Evaluation Laboratory Planning Guide aids in establishing expectations for both NASA and non- NASA facility customers. The potential audience for this guide includes both internal and commercial spaceflight hardware developers. It is intended to assist their project engineering personnel in materials analysis planning and execution. Material covered includes a roadmap of the analysis process, roles and responsibilities of facility and user, major milestones, facility capabilities, and inputs required by the facility. Samples of deliverables, products, and inputs necessary to define scope of analysis, cost, and schedule are included as an appendix to the guide.

  11. [Information Concerning Mean Test Scores for the Graduate Management Admission Test (GMAT), Graduate Record Examinations (GRE), Law School Admission Test (LSAT), Preliminary Scholastic Aptitude Test (PSAT), and Scholastic Aptitude Test (SAT) for the National Commission on Excellence in Education.

    Science.gov (United States)

    Solomon, Robert J.

    Data are provided to the National Commission on Excellence in Education on the Graduate Management Admission Test (GMAT), Graduate Record Examinations (GRE), Law School Admission Test (LSAT), Preliminary Scholastic Aptitude Test (PSAT), and Scholastic Aptitude Test (SAT). Statistics are provided on the following: yearly GMAT mean scores 1965-1966…

  12. Maintaining data quality in an environmental testing laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Cohen, Roy J.

    2001-03-05

    In today's competitive and highly litigious world, it is critical that any laboratory generating data for the environmental and allied industries have a world-class Quality Assurance Program. This Plan must conform to the requirements of every agency and client with whom the lab does business. The goal of such a program is data defensibility; i.e., data validity. Data (usually qualitative analyte [compound or element] identifications and quantitative numerical results) are the end results of nearly all analytical laboratory processes, and the source of revenue. Clients pay for results. The clients expect the results to be accurate, precise, and repeatable. If their data has to go to court, the laboratory will be called upon to defend the accuracy and precision of their work. Without a strong QA program, this will be impossible. The potential implications and repercussions of non-defensible lab data are far-reaching and very costly in terms of loss of future revenues and in legal judgments.

  13. Antimicrobial Testing Methods & Procedures Developed by EPA's Microbiology Laboratory

    Science.gov (United States)

    We develop antimicrobial testing methods and standard operating procedures to measure the effectiveness of hard surface disinfectants against a variety of microorganisms. Find methods and procedures for antimicrobial testing.

  14. FRACTIONAL CRYSALLIZATION LABORATORY TESTS WITH SIMULATED TANK WASTE

    Energy Technology Data Exchange (ETDEWEB)

    HERTING DL

    2007-11-29

    Results are presented for several simulated waste tests related to development of the fractional crystallization process. Product salt dissolution rates were measured to support pilot plant equipment design. Evaporation tests were performed to evaluate the effects of organics on slurry behavior and to determine optimum antifoam addition levels. A loss-of-power test was performed to support pilot plant accident scenario analysis. Envelope limit tests were done to address variations in feed composition.

  15. Laboratory tests of headache disorders - dawn of a new era?

    DEFF Research Database (Denmark)

    Schytz, Henrik Winther; Olesen, Jes

    2017-01-01

    and some secondary headaches. BACKGROUND: In this narrative review we present and discuss published tests that might be useful in phenotyping and/or diagnosis of long-lasting headache disorders such as migraine, tension-type headache, trigeminal autonomic cephalalgias, trigeminal neuralgia and persisting...... secondary headaches. AIM: The palpometer test, quantitative sensory testing, nociceptive blink reflex and autonomic tests may be valuable to phenotype and/or diagnose subforms of migraine, tension-type headache, cluster headache, trigeminal neuralgia and medication-overuse headache. Provocation tests...

  16. Data reproducibility of pace strategy in a laboratory test run

    Science.gov (United States)

    de França, Elias; Xavier, Ana Paula; Hirota, Vinicius Barroso; Côrrea, Sônia Cavalcanti; Caperuto, Érico Chagas

    2016-01-01

    This data paper contains data related to a reproducibility test for running pacing strategy in an intermittent running test until exhaustion. Ten participants underwent a crossover study (test and retest) with an intermittent running test. The test was composed of three-minute sets (at 1 km/h above Onset Blood Lactate Accumulation) until volitional exhaustion. To assess pace strategy change, in the first test participants chose the rest time interval (RTI) between sets (ranging from 30 to 60 s) and in the second test the maximum RTI values were either the RTI chosen in the first test (maximum RTI value), or less if desired. To verify the reproducibility of the test, rating perceived exertion (RPE), heart rate (HR) and blood plasma lactate concentration ([La]p) were collected at rest, immediately after each set and at the end of the tests. As results, RTI, RPE, HR, [La]p and time to exhaustion were not statistically different (p>0.05) between test and retest, as well as they demonstrated good intraclass correlation. PMID:27081672

  17. Environmental Survey preliminary report, Idaho National Engineering Laboratory, Idaho Falls, Idaho and Component Development and Integration Facility, Butte, Montana

    Energy Technology Data Exchange (ETDEWEB)

    1988-09-01

    This report presents the preliminary findings of the first phase of the Environmental Survey of the United States Department of Energy's (DOE) Idaho National Engineering Laboratory (INEL) and Component Development and Integration Facility (CDIF), conducted September 14 through October 2, 1987. The Survey is being conducted by an interdisciplinary team of environmental specialists, led and managed by the Office of Environment, Safety and Health's Office of Environmental Audit. The team includes outside experts supplied by a private contractor. The objective of the Survey is to identify environmental problems and areas of environmental risk associated with the INEL and CDIF. The Survey covers all environmental media and all areas of environmental regulation. It is being performed in accordance with the DOE Environmental Survey Manual. The on-site phase of the Survey involves the review of existing site environmental data, observations of the operations' carried on at the INEL and the CDIF, and interviews with site personnel. The Survey team developed a Sampling and Analysis (S A) Plan to assist in further assessing certain of the environmental problems identified during its on-site activities. The S A Plan will be executed by the Oak Ridge National Laboratory. When completed, the S A results will be incorporated into the INEL/CDIF Survey findings for inclusion into the Environmental Survey Summary Report. 90 refs., 95 figs., 77 tabs.

  18. [Ayurvedics drugs in France. Laboratories polytherapic, a test].

    Science.gov (United States)

    Raynal, Cécile; Lefebvre, Thierry

    2011-02-01

    In the beginning of the thirties, Dr Jean Saidman, who has already created a rotative solarium at Aix-les-Bains, built another one in Jamnagar (India). When he was there, he discovered ayurvedic therapy. After the Second World War, with his friends Dr Rémus Krainik and the chemist René-Henri Monceaux, he set up a "néo-ayurvedic action committee", and then a pharmaceutical laboratory, "Polythérapic", to export to french colonies patents medicines inspired by indian medicine. The authors tale this experience suddenly stopped by the unexpected death of Jean Saidman, in 1949.

  19. Tonopah test range - outpost of Sandia National Laboratories

    Energy Technology Data Exchange (ETDEWEB)

    Johnson, L.

    1996-03-01

    Tonopah Test Range is a unique historic site. Established in 1957 by Sandia Corporation, Tonopah Test Range in Nevada provided an isolated place for the Atomic Energy Commission to test ballistics and non-nuclear features of atomic weapons. It served this and allied purposes well for nearly forty years, contributing immeasurably to a peaceful conclusion to the long arms race remembered as the Cold War. This report is a brief review of historical highlights at Tonopah Test Range. Sandia`s Los Lunas, Salton Sea, Kauai, and Edgewood testing ranges also receive abridged mention. Although Sandia`s test ranges are the subject, the central focus is on the people who managed and operated the range. Comments from historical figures are interspersed through the narrative to establish this perspective, and at the end a few observations concerning the range`s future are provided.

  20. Impact of Medical School Laboratory Courses and Physician Attitude on Test Use by House Staff.

    Science.gov (United States)

    Everett, George D.; And Others

    1983-01-01

    A study to assess the impact of laboratory courses in medical school on subsequent University of Iowa house staff test use, and to assess the influence of attitudinal factors on test use patterns is reported. Physician preferences for style, format, and timing of laboratory training sessions are examined. (MSE)

  1. 78 FR 22536 - Procedural Manual for the Election Assistance Commission's Voting System Test Laboratories...

    Science.gov (United States)

    2013-04-16

    ... COMMISSION Procedural Manual for the Election Assistance Commission's Voting System Test Laboratories Program Manual, Version 2.0 AGENCY: United States Election Assistance Commission (EAC). ACTION: Notice; publication of Voting System Test Laboratories Program Manual, Version 2.0, for 60 day public comment...

  2. Idaho National Engineering Laboratory, Test Area North, Hangar 629 -- Photographs, written historical and descriptive data

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1994-12-31

    The report describes the history of the Idaho National Engineering Laboratory`s Hangar 629. The hangar was built to test the possibility of linking jet engine technology with nuclear power. The history of the project is described along with the development and eventual abandonment of the Flight Engine Test hangar. The report contains historical photographs and architectural drawings.

  3. 75 FR 51280 - Oversight of Laboratory Developed Tests; Public Meeting; Reopening of the Comment Period

    Science.gov (United States)

    2010-08-19

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration Oversight of Laboratory Developed Tests; Public Meeting... oversight of laboratory developed tests (LDTs). FDA is reopening the comment period to update comments...

  4. 42 CFR 493.1467 - Condition: Laboratories performing high complexity testing; cytology general supervisor.

    Science.gov (United States)

    2010-10-01

    ... testing; cytology general supervisor. 493.1467 Section 493.1467 Public Health CENTERS FOR MEDICARE....1467 Condition: Laboratories performing high complexity testing; cytology general supervisor. For the subspecialty of cytology, the laboratory must have a general supervisor who meets the qualification...

  5. From laboratory corrosion tests to a corrosion lifetime for wood fasteners : progress and challenges

    Science.gov (United States)

    Samuel L. Zelinka; Dominique Derome; Samuel V. Glass

    2010-01-01

    Determining a “corrosion-lifetime” for fasteners embedded in wood treated with recently adopted preservative systems depends upon successfully relating results of laboratory tests to in-service conditions. In contrast to laboratory tests where metal is embedded in wood at constant temperature and moisture content, the in-service temperature and moisture content of wood...

  6. Effects of earthquake induced rock shear on containment system integrity. Laboratory testing plan development

    Energy Technology Data Exchange (ETDEWEB)

    Read, Rodney S. (RSRead Consulting Inc. (Canada))

    2011-07-15

    This report describes a laboratory-scale testing program plan to address the issue of earthquake induced rock shear effects on containment system integrity. The document contains a review of relevant literature from SKB covering laboratory testing of bentonite clay buffer material, scaled analogue tests, and the development of related material models to simulate rock shear effects. The proposed testing program includes standard single component tests, new two-component constant volume tests, and new scaled analogue tests. Conceptual drawings of equipment required to undertake these tests are presented along with a schedule of tests. The information in this document is considered sufficient to engage qualified testing facilities, and to guide implementation of laboratory testing of rock shear effects. This document was completed as part of a collaborative agreement between SKB and Nuclear Waste Management Organization (NWMO) in Canada

  7. Reactivity of microhemagglutination, fluorescent treponemal antibody absorption, and venereal disease research laboratory tests in primary syphilis.

    Science.gov (United States)

    Dyckman, J D; Storms, S; Huber, T W

    1980-10-01

    Seroreactivity in 130 cases of primary syphilis was 91.5% by fluorescent treponemal antibody absorption test, 82.3% by microhemagglutination (MHA-TP test), and 68.5% by the Venereal Disease Reseach Laboratory (VDRL) test. The MHA TP test generally became reactive earlier than the VDRL test and confirmed all reactive and most weakly reactive VDRL results.

  8. Preliminary report on the ecological assessment of Waste Area Grouping 5 at Oak Ridge National Laboratory, Oak Ridge, Tennessee. Environmental Restoration Program

    Energy Technology Data Exchange (ETDEWEB)

    Ashwood, T.L.; Suter, G.W. II; Stewart, A.J.

    1992-09-01

    In support of the remedial investigation for Waste Area Grouping (WAG) 5, staff of the Environmental Sciences Division of Oak Ridge National Laboratory have conducted preliminary ecological assessment activities. A screening level ecological risk assessment has been completed, ambient toxicity tests have been conducted on streams and seeps within WAG 5, WAG 5 has been surveyed for rare and endangered species and wetlands, and wild turkeys that may feed on contaminated vegetation and insects in WAG 5 have been screened for beta-emitting isotopes and {sup 137}Cs. The screening-level ecological risk assessment identified some data gaps that were addressed in the ecological assessment plan. These include gaps in data on the toxicity of surface water and soil within WAG 5 and on the status of rare and endangered species. In addition, the screening-level risk assessment identified the need for data on the level of contaminants in wild turkeys that may be consumed by predatory wildlife and humans. Three rounds of ambient toxicity tests on six streams and seeps, using the microcrustacean Ceriodaphnia, have identified potential toxicity in three of the sample sites. Further tests are required to identify the toxicant. No rare or endangered animal species have been identified in the WAG 5 area.

  9. Bonding to oxide ceramics—laboratory testing versus clinical outcome.

    Science.gov (United States)

    Kern, Matthias

    2015-01-01

    Despite a huge number of published laboratory bonding studies on dental oxide ceramics clinical long-term studies on resin bonded oxide ceramic restorations are rare. The purpose of this review is to present the best available clinical evidence for successful bonding of dental oxide ceramic restorations. Clinical trials with resin-bonded restorations that had no or only limited mechanical retention and were made from alumina or zirconia ceramic were identified using an electronic search in PubMed database. Overall 10 publications with clinical trials could be identified. Their clinical outcome was compared with that laboratory bond strength studies. Clinical data provide strong evidence that air-abrasion at a moderate pressure in combination with using phosphate monomer containing primers and/or luting resins provide long-term durable bonding to glass-infiltrated alumina and zirconia ceramic under the humid and stressful oral conditions. As simple and clinically reliable bonding methods to oxide ceramics exist, the rationale for development of alternative bonding methods might be reconsidered especially when these methods are more time consuming or require rather complicated and/or technique sensitive procedures. Copyright © 2014 Academy of Dental Materials. Published by Elsevier Ltd. All rights reserved.

  10. Preliminary laboratory report of fungal infections associated with contaminated methylprednisolone injections.

    Science.gov (United States)

    Lockhart, Shawn R; Pham, Cau D; Gade, Lalitha; Iqbal, Naureen; Scheel, Christina M; Cleveland, Angela A; Whitney, Anne M; Noble-Wang, Judith; Chiller, Tom M; Park, Benjamin J; Litvintseva, Anastasia P; Brandt, Mary E

    2013-08-01

    In September 2012, the Centers for Disease Control and Prevention (CDC) initiated an outbreak investigation of fungal infections linked to injection of contaminated methylprednisolone acetate (MPA). Between 2 October 2012 and 14 February 2013, the CDC laboratory received 799 fungal isolates or human specimens, including cerebrospinal fluid (CSF), synovial fluid, and abscess tissue, from 469 case patients in 19 states. A novel broad-range PCR assay and DNA sequencing were used to evaluate these specimens. Although Aspergillus fumigatus was recovered from the index case, Exserohilum rostratum was the primary pathogen in this outbreak and was also confirmed from unopened MPA vials. Exserohilum rostratum was detected or confirmed in 191 specimens or isolates from 150 case patients, primarily from Michigan (n=67 patients), Tennessee (n=26), Virginia (n=20), and Indiana (n=16). Positive specimens from Michigan were primarily abscess tissues, while positive specimens from Tennessee, Virginia, and Indiana were primarily CSF. E. rostratum antifungal susceptibility MIC50 and MIC90 values were determined for voriconazole (1 and 2 μg/ml, respectively), itraconazole (0.5 and 1 μg/ml), posaconazole (0.5 and 1 μg/ml), isavuconazole (4 and 4 μg/ml), and amphotericin B (0.25 and 0.5 μg/ml). Thirteen other mold species were identified among case patients, and four other fungal genera were isolated from the implicated MPA vials. The clinical significance of these other fungal species remains under investigation. The laboratory response provided significant support to case confirmation, enabled linkage between clinical isolates and injected vials of MPA, and described significant features of the fungal agents involved in this large multistate outbreak.

  11. PEP Support: Laboratory Scale Leaching and Permeate Stability Tests

    Energy Technology Data Exchange (ETDEWEB)

    Russell, Renee L.; Peterson, Reid A.; Rinehart, Donald E.; Buchmiller, William C.

    2010-05-21

    This report documents results from a variety of activities requested by the Hanford Tank Waste Treatment and Immobilization Plant (WTP). The activities related to caustic leaching, oxidative leaching, permeate precipitation behavior of waste as well as chromium (Cr) leaching are: • Model Input Boehmite Leaching Tests • Pretreatment Engineering Platform (PEP) Support Leaching Tests • PEP Parallel Leaching Tests • Precipitation Study Results • Cr Caustic and Oxidative Leaching Tests. Leaching test activities using the PEP simulant provided input to a boehmite dissolution model and determined the effect of temperature on mass loss during caustic leaching, the reaction rate constant for the boehmite dissolution, and the effect of aeration in enhancing the chromium dissolution during caustic leaching. Other tests were performed in parallel with the PEP tests to support the development of scaling factors for caustic and oxidative leaching. Another study determined if precipitate formed in the wash solution after the caustic leach in the PEP. Finally, the leaching characteristics of different chromium compounds under different conditions were examined to determine the best one to use in further testing.

  12. Optimization of backfill pellet properties AASKAR DP2 - Laboratory tests

    Energy Technology Data Exchange (ETDEWEB)

    Andersson, Linus; Sanden, Torbjoern [Clay Technology AB, Lund (Sweden)

    2012-12-15

    Bentonite pellets are planned to be used as a part of the backfill in the Swedish spent nuclear fuel deep repository concept KBS-3. This report describes testing and evaluation of different backfill pellet candidates. The work completed included testing of both pellet material and pellet type. The materials tested were sourced from India (ASHA), Greece (IBECO, 2 products) and Wyoming USA (MX-80 clay). The majority of the tests were completed on the ASHA clay as well as the IBECO-RWC-BF products, with only limited testing of the others. The pellets tested were manufactured using both extrusion and roller compaction techniques and had different sizes and geometries. The following tests have been performed and are presented in this report: 1. General tests. Water content, bulk density and dry density have been determined for both the pellet filling and the individual pellets. The compressibility of the pellet filling was tested with CRS-tests and the strength of the individual pellets was tested with a special compression test. The water content varied from 11.3% to 18.7% and was highest for the extruded pellets. The dry density was somewhat higher for the roller-compacted pellets and their compressibility was lower. The strength of the individual pellets was generally higher for the extruded pellets. 2. Erosion. The pellet filling will be exposed to groundwater inflow when installed in the tunnel. This flow could possibly cause significant erosion on the pellet filling. Erosion tests have been performed with comparisons in erosion resistance made on the various material- and pellet-types. The influence of variations in water salinity and flow rates was also tested. The IBECO extruded 6- and 10- mm diameter rods and the compacted Posiva spec.-A pellet filling seem to have the lowest tendency to erode. It is also the IBECO extruded pellet filling that withstands variations in water salinity and flow rates best. 3. Water storing capacity. The pellet filling

  13. Test Results From The Idaho National Laboratory 15kW High Temperature Electrolysis Test Facility

    Energy Technology Data Exchange (ETDEWEB)

    Carl M. Stoots; Keith G. Condie; James E. O' Brien; J. Stephen Herring; Joseph J. Hartvigsen

    2009-07-01

    A 15kW high temperature electrolysis test facility has been developed at the Idaho National Laboratory under the United States Department of Energy Nuclear Hydrogen Initiative. This facility is intended to study the technology readiness of using high temperature solid oxide cells for large scale nuclear powered hydrogen production. It is designed to address larger-scale issues such as thermal management (feed-stock heating, high temperature gas handling, heat recuperation), multiple-stack hot zone design, multiple-stack electrical configurations, etc. Heat recuperation and hydrogen recycle are incorporated into the design. The facility was operated for 1080 hours and successfully demonstrated the largest scale high temperature solid-oxide-based production of hydrogen to date.

  14. Preliminary report: in-plant safety/relief valve discharge load test, Monticello Plant

    Energy Technology Data Exchange (ETDEWEB)

    Chang, H.C. (comp.)

    1976-12-01

    This preliminary report covers the results of the test program of safety/relief valve (SRV) discharge load phenomena and the effects upon the Mark I primary containment torus structure of the Monticello Nuclear Power Plant. The objectives of the test were to provide a data base for verifying/improving analytical models and to measure the structural response of the torus to SRV discharges. Objectives, instrumentation, and test plan are described. Results of continuing data evaluation will be included in the final report scheduled for publication later in 1977.

  15. Effectiveness of a computerized alert system based on re-testing intervals for limiting the inappropriateness of laboratory test requests.

    Science.gov (United States)

    Lippi, Giuseppe; Brambilla, Marco; Bonelli, Patrizia; Aloe, Rosalia; Balestrino, Antonio; Nardelli, Anna; Ceda, Gian Paolo; Fabi, Massimo

    2015-11-01

    There is consolidated evidence that the burden of inappropriate laboratory test requests is very high, up to 70%. We describe here the function of a computerized alert system linked to the order entry, designed to limit the number of potentially inappropriate laboratory test requests. A computerized alert system based on re-testing intervals and entailing the generation of pop-up alerts when preset criteria of appropriateness for 15 laboratory tests were violated was implemented in two clinical wards of the University Hospital of Parma. The effectiveness of the system for limiting potentially inappropriate tests was monitored for 6months. Overall, 765/3539 (22%) test requests violated the preset criteria of appropriateness and generated the appearance of electronic alert. After alert appearance, 591 requests were annulled (17% of total tests requested and 77% of tests alerted, respectively). The total number of test requests violating the preset criteria of inappropriateness constantly decreased over time (26% in the first three months of implementation versus 17% in the following period; ptest withdrawn was 3387 Euros (12.8% of the total test cost) throughout the study period. The results of this study suggest that a computerized alert system may be effective to limit the inappropriateness of laboratory test requests, generating significant economic saving and educating physicians to a more efficient use of laboratory resources. Copyright © 2015 The Canadian Society of Clinical Chemists. Published by Elsevier Inc. All rights reserved.

  16. Preliminary environmental analysis of a geopressured-geothermal test well in Brazoria County, Texas

    Energy Technology Data Exchange (ETDEWEB)

    White, W.A.; McGraw, M.; Gustavson, T.C.; Meriwether, J.

    1977-11-16

    Preliminary environmental data, including current land use, substrate lithology, soils, natural hazards, water resources, biological assemblages, meteorological data, and regulatory considerations have been collected and analyzed for approximately 150 km/sup 2/ of land near Chocolate Bayou, Brazoria County, Texas, in which a geopressured-geothermal test well is to be drilled in the fall of 1977. The study was designed to establish an environmental data base and to determine, within spatial constraints set by subsurface reservoir conditions, environmentally suitable sites for the proposed well. Preliminary analyses of data revealed the eed for focusing on the following areas: potential for subsidence and fault activation, susceptibility of test well and support facilities to fresh- and salt-water flooding, possible effects of produced saline waters on biological assemblages and groundwaer resources, distribution of expansive soils, and effect of drilling and associated support activities on known archeological-cultural resources.

  17. Laboratory Testing of Cyclic Laterally Loaded Pile in Cohesionless Soil

    DEFF Research Database (Denmark)

    Roesen, Hanne Ravn; Ibsen, Lars Bo; Hansen, Mette;

    2013-01-01

    Offshore wind turbines are normally founded with large diameter monopiles and placed in rough environments subjected to variable lateral loads from wind and waves. A long-term lateral loading may create rotation (tilt) of the pile by change in the pile-soil system which is critical...... in the serviceability limit state. In this paper small-scale testing of a pile subjected to cyclic, lateral loading is treated in order to investigate the effect of cyclic loading. The test setup, which is an improvement of a previous setup, is described and the first results of testing are compared with previous...

  18. Microbiological examination and proficiency testing in dairy laboratories.

    Science.gov (United States)

    Teger, S G

    2001-03-01

    This paper considers the main factors in the assessment of microbiological examination of food and discusses a few points related to validation of quantitative and qualitative microbiological methods. Within the scope of accredited methods, the author defines the terms such as conform reference, equivalence of reference method, and in-house method. The paper describes evaluation of a routine method with respect to the official method based on results obtained by automatic epifluorescent microscopy using the BactoScan 8000 instrument for determination of bacteriological quality of milk and provides general guidance for the establishment of a conversion relationship between the two methods. The paper gives an overview of the quality assurance aspects involved in the application of the routine method and concludes with an example of interlaboratory proficiency study for the epifluorescent microscopic method which is regularly applied in dairy laboratories.

  19. Content of children's loss of control eating episodes assessed by self-report and laboratory test meal.

    Science.gov (United States)

    Theim, Kelly R; Wilfley, Denise E; Beach, Elizabeth; Tanofsky-Kraff, Marian; Goldschmidt, Andrea B

    2014-01-01

    Pediatric loss of control (LOC) eating heightens risk for excessive weight gain and further disordered eating. Assessment of LOC typically involves self-report interview or laboratory test meal, although no study has concurrently examined data from both methods. We gathered eating episode data via interview (Child Eating Disorder Examination; ChEDE) and a laboratory test meal, among 22 overweight girls (aged 7-12 years) reporting LOC eating. Children consumed more energy during ChEDE episodes, although ChEDE and test meal episodes did not differ in macronutrient content. Episodes' correlation for amount consumed (grams) did not reach significance, p = .076. In exploratory analyses among the seven children reporting LOC during the test meal, episodes were significantly correlated for grams consumed. Findings provide preliminary data to suggest that semi-structured interviews accurately capture children's LOC episode quantity. Episodes did not qualitatively differ, although children reported consuming more energy during self-reported episodes. Replication is warranted in larger studies.

  20. Test for Nonlinear Input Output Relations in SISO Systems by Preliminary Data Analysis

    DEFF Research Database (Denmark)

    Knudsen, Torben

    2000-01-01

    This paper discusses and develops preliminary statistical tests for detecting nonlinearities in the deterministic part of SISO systems with noise. The most referenced method is unreliable for common noise processes as e.g.\\ colored. Therefore two new methods based on superposition and sinus input...... are developed. They are much more robust, especially the sinus method which is reliable also for colored, heavy tailed or skew distributed noise....

  1. Children’s Foreign Language Anxiety Scale: Preliminary Tests of Reliability and Validity

    OpenAIRE

    Aydın, Selami; Harputlu, Leyla; Güzel, Serhat; Uştuk, Özgehan; Savran Çelik, Şeyda; Genç, Deniz

    2016-01-01

    Foreign language anxiety (FLA), which constitutes a serious problem in the foreign language learning process, has been mainly seen as a research issue regarding adult language learners, while it has been overlooked in children. This is because there is a lack of appropriate tools to measure FLA among children, whereas there are many studies on the scales that aim to measure anxiety levels among adult learners. Thus, the current study aims to conduct the preliminary tests of reliability and va...

  2. [A technical suggestion for laboratory tests in cases of rape].

    Science.gov (United States)

    Fazio Pellacchio, M C; Celli, R

    1994-01-01

    The paper suggests completing the clinical tests carried out in cases of rape by collecting material not only from the fornix of the vagina but also from the cervical canal using cotton-wool buds, and examining any spermatozoa adhering to the cotton filaments by staining with Baecchi's method. Alternatively, the paper suggests carrying out these tests in anticipation of their possible use as forensic evidence if requested by the court.

  3. Preliminary safety analysis report for the Auxiliary Hot Cell Facility, Sandia National Laboratories, Albuquerque, New Mexico

    Energy Technology Data Exchange (ETDEWEB)

    OSCAR,DEBBY S.; WALKER,SHARON ANN; HUNTER,REGINA LEE; WALKER,CHERYL A.

    1999-12-01

    The Auxiliary Hot Cell Facility (AHCF) at Sandia National Laboratories, New Mexico (SNL/NM) will be a Hazard Category 3 nuclear facility used to characterize, treat, and repackage radioactive and mixed material and waste for reuse, recycling, or ultimate disposal. A significant upgrade to a previous facility, the Temporary Hot Cell, will be implemented to perform this mission. The following major features will be added: a permanent shield wall; eight floor silos; new roof portals in the hot-cell roof; an upgraded ventilation system; and upgraded hot-cell jib crane; and video cameras to record operations and facilitate remote-handled operations. No safety-class systems, structures, and components will be present in the AHCF. There will be five safety-significant SSCs: hot cell structure, permanent shield wall, shield plugs, ventilation system, and HEPA filters. The type and quantity of radionuclides that could be located in the AHCF are defined primarily by SNL/NM's legacy materials, which include radioactive, transuranic, and mixed waste. The risk to the public or the environment presented by the AHCF is minor due to the inventory limitations of the Hazard Category 3 classification. Potential doses at the exclusion boundary are well below the evaluation guidelines of 25 rem. Potential for worker exposure is limited by the passive design features incorporated in the AHCF and by SNL's radiation protection program. There is no potential for exposure of the public to chemical hazards above the Emergency Response Protection Guidelines Level 2.

  4. Preliminary results of orthotopic en bloc uterus and ovary transplantation in the laboratory rat.

    Science.gov (United States)

    Motoc, A; Jiga, L; Ionac, M; Raica, M; Motoc, M; Chiovschi, S

    2003-01-01

    A new experimental model of whole uterus and ovary transplantation in the laboratory rat was achieved. The main goals of this study were concerned with developing and standardizing the microsurgical technique of uterus transplantation in rats and observing the particular cellular patterns of acute allograft rejection at the level of the transplanted graft. Thirty-five orthotopic uterus transplantations were performed. An additional 20 female rats were used for dissection training sessions. Recipients were euthanasied at 24 hours, 48 hours and 72 hours. Immediate postoperative survival was 100%. Patency of the microsurgical anastomoses, checked at 24 hours, was 100%. At 72 hours thrombosis occurred in all anastomoses. The explanted uterine grafts were fixed in formaline and analyzed under light microscopy and specific imunohistochemical analysis. The acute allograft rejection has a particular cellular reaction pattern, probably due to the unique diversity of the tissues that compose it. Inflammatory cells like LTCD8+, LBCD20+ and mastocytes tend to agglomerate in the vicinity of nervous and vascular structures, showing no signs of lymphoid tissue disposition like in typical acute rejection. Uterus transplantation in rats has proven to be a valid experiment that allows us to express hope that by further research on transplantation of the uterus gynecologists will be able to introduce an adapted technique in the treatment of specific cases of human female infertility.

  5. ESO adaptive optics facility progress and first laboratory test results

    Science.gov (United States)

    Arsenault, Robin; Madec, Pierre-Yves; Paufique, Jérome; La Penna, Paolo; Stroebele, Stefan; Vernet, Elise; Pirard, Jean-Francois; Hackenberg, Wolfgang; Kuntschner, Harald; Kolb, Johann; Muller, Nicolas; Garcia-Rissmann, Aurea; Le Louarn, Miska; Amico, Paola; Hubin, Norbert; Lizon, Jean-Louis; Ridings, Rob; Haguenauer, Pierre; Abad, Jose A.; Fischer, Gerhard; Heinz, Volker; Kiekebusch, Mario; Argomedo, Javier; Conzelmann, Ralf; Tordo, Sebastien; Donaldson, Rob; Soenke, Christian; Duhoux, Philippe; Fedrigo, Enrico; Delabre, Bernard; Jost, Andrea; Duchateau, Michel; Downing, Mark; Reyes Moreno, Javier; Manescau, Antonio; Bonaccini Calia, Domenico; Quattri, Marco; Dupuy, Christophe; Guidolin, Ivan M.; Comin, Mauro; Guzman, Ronald; Buzzoni, Bernard; Quentin, Jutta; Lewis, Steffan; Jolley, Paul; Kraus, Max; Pfrommer, Thomas; Biasi, Roberto; Gallieni, Daniele; Stuik, Remko; Kaenders, Wilhelm; Ernstberger, Bernhard; Friedenauer, Axel

    2014-07-01

    The Adaptive Optics Facility project is completing the integration of its systems at ESO Headquarters in Garching. The main test bench ASSIST and the 2nd Generation M2-Unit (hosting the Deformable Secondary Mirror) have been granted acceptance late 2012. The DSM has undergone a series of tests on ASSIST in 2013 which have validated its optical performance and launched the System Test Phase of the AOF. This has been followed by the performance evaluation of the GRAAL natural guide star mode on-axis and will continue in 2014 with its Ground Layer AO mode. The GALACSI module (for MUSE) Wide-Field-Mode (GLAO) and the more challenging Narrow-Field-Mode (LTAO) will then be tested. The AOF has also taken delivery of the second scientific thin shell mirror and the first 22 Watt Sodium laser Unit. We will report on the system tests status, the performances evaluated on the ASSIST bench and advancement of the 4Laser Guide Star Facility. We will also present the near future plans for commissioning on the telescope and some considerations on tools to ensure an efficient operation of the Facility in Paranal.

  6. Seed dressing pesticides on springtails in two ecotoxicological laboratory tests.

    Science.gov (United States)

    Alves, Paulo Roger L; Cardoso, Elke J B N; Martines, Alexandre M; Sousa, José Paulo; Pasini, Amarildo

    2014-07-01

    Terrestrial ecotoxicological tests are powerful tools for assessing the ecological risks that pesticides pose to soil invertebrates, but they are rarely used to evaluate seed dressing pesticides. This study investigated the effects of seed dressing pesticides on survival and reproduction of Folsomia candida (Collembola), using standardized ecotoxicological tests (after ISO guidelines with few adaptations for tropical conditions). Commercial formulations of five seed dressing pesticides were tested individually in Tropical Artificial Soil (TAS): the insecticides imidacloprid, fipronil, thiametoxam, and the fungicides captan and carboxin+thiram. Thiametoxam, captan, and carboxin+thiram were only lethal to F. candida at the highest concentration tested (1000mg of active ingredient kg(-1) of dry soil). Imidacloprid and fipronil were lethal at lower concentrations (100 and 10mg a.i. kg(-1) soil d.w, respectively), however, these concentrations were much higher than those predicted (PEC) for soil. Imidacloprid and fipronil were the most toxic pesticides in both tests, reducing significantly collembolan reproduction (EC20=0.02 and 0.12mga.i.kg(-1) soil d.w, respectively). Further studies under more realistic conditions are needed, since imidacloprid and fipronil reduced collembolan reproduction at concentrations below or close to their respective PECs.

  7. Accuracy in HIV Rapid Testing among Laboratory and Non-laboratory Personnel in Zambia: Observations from the National HIV Proficiency Testing System.

    Directory of Open Access Journals (Sweden)

    Sheila Mwangala

    Full Text Available Despite rapid task-shifting and scale-up of HIV testing services in high HIV prevalence countries, studies evaluating accuracy remain limited. This study aimed to assess overall accuracy level and factors associated with accuracy in HIV rapid testing in Zambia.Accuracy was investigated among rural and urban HIV testing sites participating in two annual national HIV proficiency testing (PT exercises conducted in 2009 (n = 282 sites and 2010 (n = 488 sites. Testers included lay counselors, nurses, laboratory personnel and others. PT panels of five dry tube specimens (DTS were issued to testing sites by the national reference laboratory (NRL. Site accuracy level was assessed by comparison of reported results to the expected results. Non-parametric rank tests and multiple linear regression models were used to assess variation in accuracy between PT cycles and between tester groups, and to examine factors associated with accuracy respectively.Overall accuracy level was 93.1% (95% CI: 91.2-94.9 in 2009 and 96.9% (95% CI: 96.1-97.8 in 2010. Differences in accuracy were seen between the tester groups in 2009 with laboratory personnel being more accurate than non-laboratory personnel, while in 2010 no differences were seen. In both PT exercises, lay counselors and nurses had more difficulties interpreting results, with more occurrences of false-negative, false-positive and indeterminate results. Having received the standard HIV rapid testing training and adherence to the national HIV testing algorithm were positively associated with accuracy.The study showed an improvement in tester group and overall accuracy from the first PT exercise to the next. Average number of incorrect test results per 1000 tests performed was reduced from 69 to 31. Further improvement is needed, however, and the national HIV proficiency testing system seems to be an important tool in this regard, which should be continued and needs to be urgently strengthened.

  8. A LABORATORY TEST FOR THE EXAMINATION OF ALACTIC RUNNING PERFORMANCE

    Directory of Open Access Journals (Sweden)

    Armin Kibele

    2005-12-01

    Full Text Available A new testing procedure is introduced to evaluate the alactic running performance in a 10s sprint task with near-maximal movement velocity. The test is performed on a motor-equipped treadmill with inverted polarity that increases mechanical resistance instead of driving the treadmill belt. As a result, a horizontal force has to be exerted against the treadmill surface in order to overcome the resistant force of the engine and to move the surface in a backward direction. For this task, subjects lean with their hands towards the front safety barrier of the treadmill railing with a slightly inclined body posture. The required skill resembles the pushing movement of bobsleigh pilots at the start of a race. Subjects are asked to overcome this mechanical resistance and to cover as much distance as possible within a time period of 10 seconds. Fifteen male students (age: 27.7 ± 4.1 years, body height: 1.82 ± 0.46 m, body mass: 78.3 ± 6.7 kg participated in a study. As the resistance force was set to 134 N, subjects ran 35.4 ± 2.6 m on the average corresponding to a mean running velocity of 3.52 ± 0.25 m·s-1. The validity of the new test was examined by statistical inference with various measures related to alactic performance including a metabolic equivalent to estimate alactic capacity (2892 ± 525 mL O2, an estimate for the oxygen debt (2662 ± 315 ml, the step test by Margaria to estimate alactic energy flow (1691 ± 171 W, and a test to measure the maximal strength in the leg extensor muscles (2304 ± 351 N. The statistical evaluation showed that the new test is in good agreement with the theoretical assumptions for alactic performance. Significant correlation coefficients were found between the test criteria and the measures for alactic capacity (r = 0.79, p < 0.01 as well as alactic power (r = 0.77, p < 0.01. The testing procedure is easy to administer and it is best suited to evaluate the alactic capacity for bobsleigh pilots as well as for

  9. Preliminary studies of tunnel interface response modeling using test data from underground storage facilities.

    Energy Technology Data Exchange (ETDEWEB)

    Sobolik, Steven Ronald; Bartel, Lewis Clark

    2010-11-01

    correctly image the tunnel. This report represents a preliminary step in the development of a methodology to convert numerical predictions of rock properties to an estimation of the extent of rock damage around an underground facility and its corresponding seismic velocity, and the corresponding application to design a testing methodology for tunnel detection.

  10. PRELIMINARY FRIT DEVELOPMENT AND MELT RATE TESTING FOR SLUDGE BATCH 6 (SB6)

    Energy Technology Data Exchange (ETDEWEB)

    Fox, K.; Miller, D.; Edwards, T.

    2009-07-21

    The Liquid Waste Organization (LWO) provided the Savannah River National Laboratory (SRNL) with a Sludge Batch 6 (SB6) composition projection in March 2009. Based on this projection, frit development efforts were undertaken to gain insight into compositional effects on the predicted and measured properties of the glass waste form and to gain insight into frit components that may lead to improved melt rate for SB6-like compositions. A series of Sludge Batch 6 (SB6) based glasses was selected, fabricated and characterized in this study to better understand the ability of frit compositions to accommodate uncertainty in the projected SB6 composition. Acceptable glasses (compositions where the Product Composition Control System (PCCS) Measurement Acceptability Region (MAR) predicted acceptable properties, good chemical durability was measured, and no detrimental nepheline crystallization was observed) can be made using Frit 418 with SB6 over a range of Na{sub 2}O and Al{sub 2}O{sub 3} concentrations. However, the ability to accommodate variation in the sludge composition limits the ability to utilize alternative frits for potential improvements in melt rate. Frit 535, which may offer improvements in melt rate due to its increased B2O3 concentration, produced acceptable glasses with the baseline SB6 composition at waste loadings of 34 and 42%. However, the PCCS MAR results showed that it is not as robust as Frit 418 in accommodating variation in the sludge composition. Preliminary melt rate testing was completed in the Melt Rate Furnace (MRF) with four candidate frits for SB6. These four frits were selected to evaluate the impacts of B{sub 2}O{sub 3} and Na{sub 2}O concentrations in the frit relative to those of Frit 418, although they are not necessarily candidates for SB6 vitrification. Higher concentrations of B{sub 2}O{sub 3} in the frit relative to that of Frit 418 appeared to improve melt rate. However, when a higher concentration of B{sub 2}O{sub 3} was coupled

  11. Laboratory Jet Erosion Tests on the Lower American River Soil Samples, Sacramento, CA- Phase 2

    Science.gov (United States)

    2017-05-01

    ER D C/ G SL T R- 17 -8 Laboratory Jet Erosion Tests on the Lower American River Soil Samples, Sacramento, CA – Phase 2 G eo te ch ni...Jet Erosion Tests on the Lower American River Soil Samples, Sacramento, CA – Phase 2 Johannes L. Wibowo and Bryant A. Robbins Geotechnical and...laboratory Jet Erosion Tests performed on Plexiglas tube samples obtained from the Lower American River (LAR) between River Mile (RM) 6.0 and RM

  12. Cognitive Laboratory Experiences : On Pre-testing Computerised Questionnaires

    NARCIS (Netherlands)

    Snijkers, G.J.M.E.

    2002-01-01

    In the literature on questionnaire design and survey methodology, pre-testing is mentioned as a way to evaluate questionnaires (i.e. investigate whether they work as intended) and control for measurement errors (i.e. assess data quality). As the American Statistical Association puts it (ASA, 1999, p

  13. Laboratory longitudinal diffusion tests: 2. Parameter estimation by inverse analysis

    Science.gov (United States)

    Takeda, M.; Zhang, M.; Nakajima, H.; Hiratsuka, T.

    2008-04-01

    This study focuses on the verification of test interpretations for different state analyses of diffusion experiments. Part 1 of this study identified that steady, quasi-steady and equilibrium state analyses for the through- and in-diffusion tests with solution reservoirs are generally feasible where the tracer is not highly sorptive. In Part 2 we investigate parameter identifiability in transient-state analysis of reservoir concentration variation using a numerical approach. For increased generality, the analytical models, objective functions and Jacobian matrix necessary for inverse analysis of transient-state data are reformulated using unified dimensionless parameters. In these dimensionless forms, the number of unknown parameters is reduced and a single dimensionless parameter represents the sorption property. The dimensionless objective functions are evaluated for individual test methods and parameter identifiability is discussed in relation to the sorption property. The effects of multiple minima and measurement error on parameter identifiability are also investigated. The main findings are that inverse problems for inlet and outlet reservoir concentration analyses are generally unstable and well-posed, respectively. Where the tracer is sorptive, the inverse problem for the inlet reservoir concentration analysis may have multiple minima. When insufficient measurement data is collected, multiple solutions may result and this should be taken into consideration when inversely analyzing data including that of inlet reservoir concentration. Verification of test interpretation by cross-checking different state analyses is feasible where the tracer is not highly sorptive. In an actual experiment, test interpretation validity is demonstrated through consistency between theory and practice for different state analyses.

  14. Laboratory and clinical evaluation of on-site urine drug testing.

    Science.gov (United States)

    Beck, Olof; Carlsson, Sten; Tusic, Marinela; Olsson, Robert; Franzen, Lisa; Hulten, Peter

    2014-11-01

    Products for on-site urine drug testing offer the possibility to perform screening for drugs of abuse directly at the point-of-care. This is a well-established routine in emergency and dependency clinics but further evaluation of performance is needed due to inherent limitations with the available products. Urine drug testing by an on-site product was compared with routine laboratory methods. First, on-site testing was performed at the laboratory in addition to the routine method. Second, the on-site testing was performed at a dependency clinic and urine samples were subsequently sent to the laboratory for additional analytical investigation. The on-site testing products did not perform with assigned cut-off levels. The subjective reading between the presence of a spot (i.e. negative test result) being present or no spot (positive result) was difficult in 3.2% of the cases, and occurred for all parameters. The tests performed more accurately in drug negative samples (specificity 96%) but less accurately for detecting positives (sensitivity 79%). Of all incorrect results by the on-site test the proportion of false negatives was 42%. The overall agreement between on-site and laboratory testing was 95% in the laboratory study and 98% in the clinical study. Although a high degree of agreement was observed between on-site and routine laboratory urine drug testing, the performance of on-site testing was not acceptable due to significant number of false negative results. The limited sensitivity of on-site testing compared to laboratory testing reduces the applicability of these tests.

  15. Argonne National Laboratory`s photo-oxidation organic mixed waste treatment system - installation and startup testing

    Energy Technology Data Exchange (ETDEWEB)

    Shearer, T.L.; Nelson, R.A.; Torres, T.; Conner, C.; Wygmans, D.

    1997-09-01

    This paper describes the installation and startup testing of the Argonne National Laboratory (ANL-E) Photo-Oxidation Organic Mixed Waste Treatment System. This system will treat organic mixed (i.e., radioactive and hazardous) waste by oxidizing the organics to carbon dioxide and inorganic salts in an aqueous media. The residue will be treated in the existing radwaste evaporators. The system is installed in the Waste Management Facility at the ANL-E site in Argonne, Illinois. 1 fig.

  16. Standard Test Method for Laboratory Aging of Sandwich Constructions

    CERN Document Server

    American Society for Testing and Materials. Philadelphia

    1999-01-01

    1.1 This test method covers the determination of the resistance of sandwich panels to severe exposure conditions as measured by the change in selected properties of the material after exposure. The exposure cycle to which the specimen is subjected is an arbitrary test having no correlation with natural weathering conditions. 1.2 The values stated in SI units are to be regarded as the standard. The inch-pound units given may be approximate. 1.3 This standard does not purport to address all of the safety concerns, if any, associated with its use. It is the responsibility of the user of this standard to establish appropriate safety and health practices and determine the applicability of regulatory limitations prior to use.

  17. The Wastewater Treatment Test Facility at Oak Ridge National Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Richardson, S.A.; Kent, T.E.; Taylor, P.A. [Oak Ridge National Lab., TN (United States)

    1995-12-01

    The Wastewater Treatment Test Facility (WTTF) contains 0.5 L/min test systems which provide a wide range of physical and chemical separation unit operations. The facility is a modified 48 foot trailer which contains all the unit operations of the ORNL`s Process Waste Treatment Plant and Nonradiological Wastewater Treatment Plant including chemical precipitation, clarification, filtration, ion-exchange, air stripping, activated carbon adsorption, and zeolite system. This facility has been used to assess treatability of potential new wastewaters containing mixed radioactive, hazardous organic, and heavy metal compounds. With the ability to simulate both present and future ORNL wastewater treatment systems, the WTTF has fast become a valuable tool in solving wastewater treatment problems at the Oak Ridge reservation.

  18. Lysosomal storage disorders: Molecular basis and laboratory testing

    Directory of Open Access Journals (Sweden)

    Filocamo Mirella

    2011-03-01

    Full Text Available Abstract Lysosomal storage disorders (LSDs are a large group of more than 50 different inherited metabolic diseases which, in the great majority of cases, result from the defective function of specific lysosomal enzymes and, in cases, of non-enzymatic lysosomal proteins or non-lysosomal proteins involved in lysosomal biogenesis. The progressive lysosomal accumulation of undegraded metabolites results in generalised cell and tissue dysfunction, and, therefore, multi-systemic pathology. Storage may begin during early embryonic development, and the clinical presentation for LSDs can vary from an early and severe phenotype to late-onset mild disease. The diagnosis of most LSDs--after accurate clinical/paraclinical evaluation, including the analysis of some urinary metabolites--is based mainly on the detection of a specific enzymatic deficiency. In these cases, molecular genetic testing (MGT can refine the enzymatic diagnosis. Once the genotype of an individual LSD patient has been ascertained, genetic counselling should include prediction of the possible phenotype and the identification of carriers in the family at risk. MGT is essential for the identification of genetic disorders resulting from non-enzymatic lysosomal protein defects and is complementary to biochemical genetic testing (BGT in complex situations, such as in cases of enzymatic pseudodeficiencies. Prenatal diagnosis is performed on the most appropriate samples, which include fresh or cultured chorionic villus sampling or cultured amniotic fluid. The choice of the test--enzymatic and/or molecular--is based on the characteristics of the defect to be investigated. For prenatal MGT, the genotype of the family index case must be known. The availability of both tests, enzymatic and molecular, enormously increases the reliability of the entire prenatal diagnostic procedure. To conclude, BGT and MGT are mostly complementary for post- and prenatal diagnosis of LSDs. Whenever genotype

  19. An audit of serological tests carried out at clinical laboratory of Ayub Teaching Hospital, Abbottabad.

    Science.gov (United States)

    Ally, Sirajuddin Hassan; Ahmed, Ayesha; Hanif, Ruhila

    2005-01-01

    Clinical audit is an important tool for reviewing and improving the quality of service in clinical laboratories. Here we present an audit of total serology test requests and the frequency of positive tests out of these in a calendar year. This is an audit of serology tests carried out at Microbiology section of Clinical Laboratory of Ayub Teaching Hospital, Abbottabad. We counted all the serology test requests for the year 2004. These tests requests were grouped month wise. The frequency of positive tests out of the total test requests were calculated. The tests included Widal, Toxoplasma, Brucella, Anti DNA, Anti Nuclear factor (ANF), Rheumatoid Arthritis Factor (RAF), HIV, HBsAg, HCV, Intra Chromatographic Technique for tuberculosis (ICT-TB), Purified Protein Derivative (PPD), Venereal Disease Research Laboratory (VDRL) test, Anti-Streptolysin-O-test (ASOT) and pregnancy test. This audit gives a clear idea of trends of test requests in our hospital. It reflects accuracy of clinicians' judgment in some tests and failure in others, prevalence of different diseases, seasonal variation in number of test requests for some tests and impact of awareness campaigns on attitude of clinicians towards certain diseases. This will help us in planning our laboratory requirements to improve quality.

  20. Development of a novel SCADA system for laboratory testing.

    Science.gov (United States)

    Patel, M; Cole, G R; Pryor, T L; Wilmot, N A

    2004-07-01

    This document summarizes the supervisory control and data acquisition (SCADA) system that allows communication with, and controlling the output of, various I/O devices in the renewable energy systems and components test facility RESLab. This SCADA system differs from traditional SCADA systems in that it supports a continuously changing operating environment depending on the test to be performed. The SCADA System is based on the concept of having one Master I/O Server and multiple client computer systems. This paper describes the main features and advantages of this dynamic SCADA system, the connections of various field devices to the master I/O server, the device servers, and numerous software features used in the system. The system is based on the graphical programming language "LabVIEW" and its "Datalogging and Supervisory Control" (DSC) module. The DSC module supports a real-time database called the "tag engine," which performs the I/O operations with all field devices attached to the master I/O server and communications with the other tag engines running on the client computers connected via a local area network. Generic and detailed communication block diagrams illustrating the hierarchical structure of this SCADA system are presented. The flow diagram outlining a complete test performed using this system in one of its standard configurations is described.

  1. [Approval of ISO/IEC 17025 and quality control of laboratory testing].

    Science.gov (United States)

    Yamamoto, Shigeki; Asakura, Hiroshi; Machii, Kenji; Igimi, Shizunobu

    2010-01-01

    First section of Division of Biomedical Food Research, National Institute of Health Sciences (NIHS) was approved by ISO/IEC 17025 as a laboratory having an appropriate laboratory testing technique. NIHS is the first national laboratory approved by ISO/IEC 17025. NIHS has also been accepted the appropriate technique and facility for the BSL3 level pathogens by ISO/IEC 17025. NIHS is necessary to take an external audit almost every year. This approval is renewed every 4 years.

  2. Beam Dynamics for the Preliminary Phase of the New CLIC Test Facility (CTF3)

    CERN Document Server

    Corsini, R; Rinolfi, Louis; Risselada, Thys; Royer, P; Tecker, F A

    2001-01-01

    In the framework of the CLIC (Compact Linear Collider) RF power source studies, the scheme of electron pulse compression and bunch frequency mulitiplication, using injection by RF deflectors into an isochronous ring, will be tested, at low charge, during the preliminary phase of the new CLIC Test Facility (CTF3) at CERN. In this paper, we describe the beam dynamics studies made in order to assess the feasibility of the bunch combination experiment, as well as the related beam measurements performed on the LEP Pre-Injector complex (LPI) before its transformation into CTF3

  3. Blade system design studies volume II : preliminary blade designs and recommended test matrix.

    Energy Technology Data Exchange (ETDEWEB)

    Griffin, Dayton A. (Global Energy Concepts, LLC, Kirkland, WA)

    2004-06-01

    As part of the U.S. Department of Energy's Wind Partnerships for Advanced Component Technologies (WindPACT) program, Global Energy Concepts, LLC is performing a Blade System Design Study (BSDS) concerning innovations in materials, processes and structural configurations for application to wind turbine blades in the multi-megawatt range. The BSDS Volume I project report addresses issues and constraints identified to scaling conventional blade designs to the megawatt size range, and evaluated candidate materials, manufacturing and design innovations for overcoming and improving large blade economics. The current report (Volume II), presents additional discussion of materials and manufacturing issues for large blades, including a summary of current trends in commercial blade manufacturing. Specifications are then developed to guide the preliminary design of MW-scale blades. Using preliminary design calculations for a 3.0 MW blade, parametric analyses are performed to quantify the potential benefits in stiffness and decreased gravity loading by replacement of a baseline fiberglass spar with carbon-fiberglass hybrid material. Complete preliminary designs are then presented for 3.0 MW and 5.0 MW blades that incorporate fiberglass-to-carbon transitions at mid-span. Based on analysis of these designs, technical issues are identified and discussed. Finally, recommendations are made for composites testing under Part I1 of the BSDS, and the initial planned test matrix for that program is presented.

  4. Hydraulic laboratory testing of Sontek-IQ Plus

    Science.gov (United States)

    Fulford, Janice M.; Kimball, Scott

    2015-11-10

    The SonTek-IQ Plus (IQ Plus) is a bottom-mounted Doppler instrument used for the measurement of water depth and velocity. Evaluation testing of the IQ Plus was performed to assess the accuracy of water depth, discharge, and velocity measurements. The IQ Plus met the manufacturer’s specifications and the U.S. Geological Survey (USGS) standard for depth accuracy measurement when the unit was installed, according to the manufacturer’s instructions, at 0 degrees pitch and roll. However, because of the limited depth testing conducted, the depth measurement is not recommended as a primary stage measurement. The IQ Plus was tested in a large indoor tilting flume in a 5-foot (ft) wide, approximately 2.3-ft deep section with mean velocities of 0.5, 1, 2, and 3 ft per second. Four IQ Plus instruments using firmware 1.52 tested for water-discharge accuracy using SonTek’s “theoretical” discharge method had a negative bias of -2.4 to -11.6 percent when compared with discharge measured with a SonTek FlowTracker and the midsection discharge method. The IQ Pluses with firmware 1.52 did not meet the manufacturer’s specification of +/-1 percent for measuring velocity. Three IQ Pluses using firmware 1.60 and SonTek’s “theoretical” method had a difference of -1.6 to -7.9 percent when compared with discharge measured with a SonTek FlowTracker and the midsection method. Mean-velocity measurements with firmware 1.60 met the manufacturer’s specification and Price Type AA meter accuracy requirements when compared with FlowTracker measurements. Because of the instrument’s velocity accuracy, the SonTek-IQ Plus with firmware 1.60 is considered acceptable for use as an index velocity instrument for the USGS. The discharge computed by the SonTek-IQ Plus during the tests had a substantial negative bias and will not be as accurate as a discharge computed with the index velocity method. The USGS does not recommend the use of undocumented computation methods, such as Son

  5. Canadian Public Health Laboratory Network laboratory Guidelines for the Use of Serological Tests (excluding point-of-care tests for the Diagnosis of Syphilis in Canada

    Directory of Open Access Journals (Sweden)

    Paul N Levett

    2015-01-01

    Full Text Available Syphilis, caused by the bacterium Treponema pallidum subsp. pallidum, is an infection recognized since antiquity. It was first reported at the end of the 15th century in Europe. Infections may be sexually transmitted as well as spread from an infected mother to her fetus or through blood transfusions. The laboratory diagnosis of syphilis infection is complex. Because this organism cannot be cultured, serology is used as the principal diagnostic method. Some of the issues related to serological diagnoses are that antibodies take time to appear after infection, and serology screening tests require several secondary confirmatory tests that can produce complex results needing interpretation by experts in the field. Traditionally, syphilis screening was performed using either rapid plasma reagin or Venereal Disease Research Laboratory tests, and confirmed by treponemal tests such as MHA-TP, TPPA or FTA-Abs. Currently, that trend is reversed, ie, most of the laboratories in Canada now screen for syphilis using treponemal enzyme immunoassays and confirm the status of infection using rapid plasma reagin or Venereal Disease Research Laboratory tests; this approach is often referred to as the reverse algorithm. This chapter reviews guidelines for specimen types and sample collection, treponemal and non-treponemal tests utilized in Canada, the current status of serological tests for syphilis in Canada, the complexity of serological diagnosis of syphilis infection and serological testing algorithms. Both traditional and reverse sequence algorithms are recommended and the algorithm used should be based on a combination of local disease epidemiology, test volumes, performance of the proposed assays and available resources.

  6. Canadian Public Health Laboratory Network laboratory guidelines for the use of serological tests (excluding point-of-care tests) for the diagnosis of syphilis in Canada.

    Science.gov (United States)

    Levett, Paul N; Fonseca, Kevin; Tsang, Raymond Sw; Kadkhoda, Kamran; Serhir, Bouchra; Radons, Sandra M; Morshed, Muhammad

    2015-01-01

    Syphilis, caused by the bacterium Treponema pallidum subsp. pallidum, is an infection recognized since antiquity. It was first reported at the end of the 15th century in Europe. Infections may be sexually transmitted as well as spread from an infected mother to her fetus or through blood transfusions. The laboratory diagnosis of syphilis infection is complex. Because this organism cannot be cultured, serology is used as the principal diagnostic method. Some of the issues related to serological diagnoses are that antibodies take time to appear after infection, and serology screening tests require several secondary confirmatory tests that can produce complex results needing interpretation by experts in the field. Traditionally, syphilis screening was performed using either rapid plasma reagin or Venereal Disease Research Laboratory tests, and confirmed by treponemal tests such as MHA-TP, TPPA or FTA-Abs. Currently, that trend is reversed, ie, most of the laboratories in Canada now screen for syphilis using treponemal enzyme immunoassays and confirm the status of infection using rapid plasma reagin or Venereal Disease Research Laboratory tests; this approach is often referred to as the reverse algorithm. This chapter reviews guidelines for specimen types and sample collection, treponemal and non-treponemal tests utilized in Canada, the current status of serological tests for syphilis in Canada, the complexity of serological diagnosis of syphilis infection and serological testing algorithms. Both traditional and reverse sequence algorithms are recommended and the algorithm used should be based on a combination of local disease epidemiology, test volumes, performance of the proposed assays and available resources.

  7. [Assessment of the quality of laboratory diagnosis of intestinal parasitic diseases by the laboratories participating in the Federal System of External Quality Assessment of Clinical Laboratory Testing].

    Science.gov (United States)

    Malakhov, V N; Dovgalev, A S; Astanina, S Iu; Serdiuk, A P

    2014-01-01

    In 2010-2013, the quality of microscopic detection of the causative agents ofparasitic diseases in the feces has been assessed by the specialists of the laboratories of the therapeutic-and-prophylactic institutions (TPIs) and Hygiene and Epidemiology Centers, Russian Inspectorate for the Protection of Consumer Rights and Human Welfare, which are participants of the Federal System of External Quality Assessment of Clinical Laboratory Testing. Thirty-two specimens containing 16 species of human helminths and 4 species of enteric protozoa in different combinations were examined. The findings suggest that the quality of microscopic detection of the causative agents of parasitic diseases is low in the laboratories of health care facilities and that the specialists of the laboratories of TPIs and Hygiene and Epidemiology Centers, Russian Inspectorate for the Protection of Consumer Rights and Human Welfare, do not not possess the knowledge and skills necessary to make a laboratory diagnosis of helminths and enteric protozoa. The average detection rates of helminths and protozoa were at a level of 64 and 36%, respectively. The correct results showed that the proportion of helminths and protozoa were 94.5 and 5.5%, respectively. According to the biological and epidemiological classification of helminths, there were higher detection rates for contact group parasites (Enterobius vermicularis and Hymenolepis nana) and geohelminths (Ascaris, Trichuris trichiura, and others). Biohelminths (Opisthorchis, tapeworms, and others) Were detectable slightly worse.

  8. Point of care testing: diagnosis outside the virology laboratory.

    Science.gov (United States)

    Blyth, Christopher C; Booy, Robert; Dwyer, Dominic E

    2011-01-01

    Numerous point-of-care tests (POCTs) are available to diagnose viral infections in both hospital and community settings. The ideal POCT is rapid, sensitive, specific, and simple to perform. This chapter will describe the benefits of POCTs, factors that can influence the accuracy of POCTs and highlight some limitations of POCT strategies. The sensitivity, specificity, and turn-around time of available POCTs are included for common conditions including respiratory viral infections (e.g. influenza, RSV) and blood-borne viral infections (e.g. HIV).

  9. Vehicle Testing and Integration Facility; NREL (National Renewable Energy Laboratory)

    Energy Technology Data Exchange (ETDEWEB)

    None

    2015-03-02

    Engineers at the National Renewable Energy Laboratory’s (NREL’s) Vehicle Testing and Integration Facility (VTIF) are developing strategies to address two separate but equally crucial areas of research: meeting the demands of electric vehicle (EV) grid integration and minimizing fuel consumption related to vehicle climate control. Dedicated to renewable and energy-efficient solutions, the VTIF showcases technologies and systems designed to increase the viability of sustainably powered vehicles. NREL researchers instrument every class of on-road vehicle, conduct hardware and software validation for EV components and accessories, and develop analysis tools and technology for the Department of Energy, other government agencies, and industry partners.

  10. Analytical Chemistry Laboratory (ACL) procedure compendium. Volume 6, Physical testing

    Energy Technology Data Exchange (ETDEWEB)

    1993-08-01

    This volume contains the interim change notice for physical testing. Covered are: properties of solutions, slurries, and sludges; rheological measurement with cone/plate viscometer; % solids determination; particle size distribution by laser scanning; penetration resistance of radioactive waste; operation of differential scanning calorimeter, thermogravimetric analyzer, and high temperature DTA and DSC; sodium rod for sodium bonded fuel; filling SP-100 fuel capsules; sodium filling of BEATRIX-II type capsules; removal of alkali metals with ammonia; specific gravity of highly radioactive solutions; bulk density of radioactive granular solids; purification of Li by hot gettering/filtration; and Li filling of MOTA capsules.

  11. Preliminary study of effects of military obscurant smokes on flora and fauna during field and laboratory exposures. Final technical report

    Energy Technology Data Exchange (ETDEWEB)

    Schaeffer, D.J.; Lower, W.R.; Kapila, S.; Yanders, A.F.; Wang, R.

    1986-12-01

    Since continued routine use of obscurant smokes could be detrimental to the native flora and fauna of training sites, a preliminary biological and chemical study of smokes was conducted to determine whether tests could be developed to demonstrate measurable changes in organisms exposed to smokes and to evaluate whether short exposures to smokes produced measurable changes in the organisms tested. Fog oil, hexachloroethane, and tank diesel smokes were tested. Tradescantia clones were examined for mutagenic effects indicated by micronuclei induction in developing pollen and pink somatic mutations in stamen hairs. Photosynthetic perturbations were measured in Tradescantia and Ambrosia dumosa using variable fluorescence induction. Animals were examined for sister chromatid exchanges and chromosome aberrations. It was found that all of the smokes tested exerted varying degrees of physiological and mutagenic effects in one or several of the assay systems at one or more of the exposure distances. These studies indicate that exposed ecological systems, or at least components of these systems, are at a higher risk than are control organisms for several types of damage attributed to obscurant smoke exposure.

  12. NREL Highlight: Truck Platooning Testing; NREL (National Renewable Energy Laboratory)

    Energy Technology Data Exchange (ETDEWEB)

    None

    2015-05-21

    NREL's fleet test and evaluation team assesses the fuel savings potential of semi-automated truck platooning of line-haul sleeper cabs with modern aerodynamics. Platooning reduces aerodynamic drag by grouping vehicles together and safely decreasing the distance between them via electronic coupling, which allows multiple vehicles to accelerate or brake simultaneously. In 2014, the team conducted track testing of three SmartWay tractor - two platooned tractors and one control tractor—at varying steady-state speeds, following distances, and gross vehicle weights. While platooning improved fuel economy at all speeds, travel at 55 mph resulted in the best overall miles per gallon. The lead truck demonstrated fuel savings up to 5.3% while the trailing truck saved up to 9.7%. A number of conditions impact the savings attainable, including ambient temperature, distance between lead and trailing truck, and payload weight. Future studies may look at ways to optimize system fuel efficiency and emissions reductions.

  13. Laboratory testing of novel sealant for leaky wells

    Energy Technology Data Exchange (ETDEWEB)

    Bibic, O. [EnCana Corp., Calgary, AB (Canada); Polikar, M. [Alberta Univ., Edmonton, AB (Canada); Boyd, J. [Seal-MastR Systems Ltd., Clagary, AB (Canada)

    2006-07-01

    Abandoned gas wells in western Canada often leak gas to the surface. An experimental study was conducted in order to determine the possibility of using an asphalt-in-water emulsion as sealant for abandoned leaky wells. This is considered a more efficient and cost-effective method to the conventional cement grout barrier. The study objective was to test this new sealant technology proposed by Seal-MastR and to examine the effect of those parameters affecting the placement and fixing of an emulsion in the near well bore matrix, thereby hindering the flow of water or gas. Two types of experiments were conducted as part of this study. The mechanism of the emulsion penetration into the porous matrix was studied making observations of the process in a transparent core holder. The process was investigated using a steel core holder that allows injection of the emulsion at actual well pressures. It was concluded that the asphalt-in-water emulsion technology can be used with success for sealing abandoned gas-leaking wells or water-producing formations. The study also proposed recommendations for field application and suggested areas for further research to improve the process, such as finding the optimum concentration for the surfactant solution pre-flush that would yield the highest penetration, and testing the emulsion in oil-wet or partially oil-wet formation. 4 refs., 3 tabs., 19 figs.

  14. The application of data from proficiency testing to laboratory accreditation according to ISO 17025

    DEFF Research Database (Denmark)

    Heydorn, Kaj

    2008-01-01

    Current methods of testing laboratories for their proficiency in reporting correct measurement results are liable to substantial errors of the 2nd kind. This means that laboratories with deflated uncertainties are accepted as proficient, even though their reported measurement results pave the way...

  15. Laboratory evaluation of the pivot-shift phenomenon with use of kinetic analysis: a preliminary study.

    Science.gov (United States)

    Sanchis-Alfonso, Vicente; Baydal-Bertomeu, José-María; Castelli, Andrea; Montesinos-Berry, Erik; Marín-Roca, Susana; Garrido-Jaén, José-David

    2011-07-06

    Currently, a suitable and reliable noninvasive method to evaluate rotational stability in vivo in anterior cruciate ligament-deficient knees, particularly during sports movements, does not exist. We speculated that if there is a rotational instability, the patient would avoid reaching a high pivoting moment during pivoting activities as a defense mechanism, and that the ground reaction moment, as registered by dynamometric platforms, would be reduced. On the basis of this hypothesis, we developed a study using kinetic analysis to evaluate rotational stability under dynamic loading. Thirty recreationally active athletes, including fifteen healthy subjects and fifteen with an anterior cruciate ligament-deficient knee, were recruited for this study. Patients performed jumping with pivoting with internal tibial rotation and external tibial rotation on the dynamometric platform with both the healthy and the injured limb. The quantitative results were graphically plotted, and the following parameters were evaluated: loading moment, pivoting moment, torque amplitude, loading slope, pivoting slope, percentage of pivoting with load, loading impulse, pivoting impulse, and maximum body rotation angle. There were no significant differences between the dominant and nondominant knees in the control group during the jumping with pivoting and external tibial rotation test with regard to the pivoting moment (p = 0.805), pivoting slope (p = 0.716), pivoting impulse 2 (p = 0.858), and pivoting impulse 3 (p = 0.873). In patients with a chronic tear of the anterior cruciate ligament, there was a significant decrease of the pivoting moment (p = 0.02), pivoting slope (p = 0.005), pivoting impulse 2 (p = 0.006), and pivoting impulse 3 (p = 0.035) during the jumping with pivoting and external tibial rotation test in the anterior cruciate ligament-deficient knee compared with the healthy, contralateral knee. Kinetic analysis with use of a dynamic platform can objectively detect alterations

  16. Lawrence Livermore National Laboratory ULTRA-350 Test Bed

    Energy Technology Data Exchange (ETDEWEB)

    Hopkins, D J; Wulff, T A; Carlisle, K

    2001-04-10

    LLNL has many in-house designed high precision machine tools. Some of these tools include the Large Optics Diamond Turning Machine (LODTM) [1], Diamond Turning Machine No.3 (DTM-3) and two Precision Engineering Research Lathes (PERL-I and PERL-II). These machines have accuracy in the sub-micron range and in most cases position resolution in the couple of nanometers range. All of these machines are built with similar underlying technologies. The machines use capstan drive technology, laser interferometer position feedback, tachometer velocity feedback, permanent magnet (PM) brush motors and analog velocity and position loop servo compensation [2]. The machine controller does not perform any servo compensation it simply computes the differences between the commanded position and the actual position (the following error) and sends this to a D/A for the analog servo position loop. LLNL is designing a new high precision diamond turning machine. The machine is called the ULTRA 350 [3]. In contrast to many of the proven technologies discussed above, the plan for the new machine is to use brushless linear motors, high precision linear scales, machine controller motor commutation and digital servo compensation for the velocity and position loops. Although none of these technologies are new and have been in use in industry, applications of these technologies to high precision diamond turning is limited. To minimize the risks of these technologies in the new machine design, LLNL has established a test bed to evaluate these technologies for application in high precision diamond turning. The test bed is primarily composed of commercially available components. This includes the slide with opposed hydrostatic bearings, the oil system, the brushless PM linear motor, the two-phase input three-phase output linear motor amplifier and the system controller. The linear scales are not yet commercially available but use a common electronic output format. As of this writing, the final

  17. Lawrence Livermore National Laboratory ULTRA-350 Test Bed

    Energy Technology Data Exchange (ETDEWEB)

    Hopkins, D J; Wulff, T A; Carlisle, K

    2001-04-10

    LLNL has many in-house designed high precision machine tools. Some of these tools include the Large Optics Diamond Turning Machine (LODTM) [1], Diamond Turning Machine No.3 (DTM-3) and two Precision Engineering Research Lathes (PERL-1 and PERL-11). These machines have accuracy in the sub-micron range and in most cases position resolution in the couple of nanometers range. All of these machines are built with similar underlying technologies. The machines use capstan drive technology, laser interferometer position feedback, tachometer velocity feedback, permanent magnet (PM) brush motors and analog velocity and position loop servo compensation [2]. The machine controller does not perform any servo compensation it simply computes the differences between the commanded position and the actual position (the following error) and sends this to a D/A for the analog servo position loop. LLNL is designing a new high precision diamond turning machine. The machine is called the ULTRA 350 [3]. In contrast to many of the proven technologies discussed above, the plan for the new machine is to use brushless linear motors, high precision linear scales, machine controller motor commutation and digital servo compensation for the velocity and position loops. Although none of these technologies are new and have been in use in industry, applications of these technologies to high precision diamond turning is limited. To minimize the risks of these technologies in the new machine design, LLNL has established a test bed to evaluate these technologies for application in high precision diamond turning. The test bed is primarily composed of commercially available components. This includes the slide with opposed hydrostatic bearings, the oil system, the brushless PM linear motor, the two-phase input three-phase output linear motor amplifier and the system controller. The linear scales are not yet commercially available but use a common electronic output format. As of this writing, the final

  18. MODERN APPROACHES IN COMPLEX LABORATORY TESTING FOR DIPHTHERIA

    Directory of Open Access Journals (Sweden)

    L. A. Kraeva

    2012-01-01

    Full Text Available Abstract. The criteria of reliable validation of population protection against diphtheria on the base of two indices including quantity of antitoxic antibodies to diphtheria and avidity index have been established. For this purposes it was proposed to use the modified variant of ELISA allowed to detect both indices simultaneously. The formula of probable development of diphtheria in case of the close contact with patients or Corynebacterium diphtheriae bacteria carriers as well as determination of revaccination time have been proposed. The authors developed “The algorithm of population immunity control and assessment of non-susceptibility to diphtheria” and “The algorithm of micro biological testing of clinical samples for C. diphtheriae”.

  19. Preliminary laboratory assessments of a lightweight geocomposite material for embankment fill application

    Directory of Open Access Journals (Sweden)

    Felix Okonta

    2015-03-01

    Full Text Available The cost of retaining structures used for the lateral support of roadside embankments can be significantly reduced through the use of lightly cemented mixtures of expanded polystyrene (EPS beads and backfill soils as lightweight roadside embankment material. Four grades of residually derived sandy soils were mixed with EPS beads and the geocomposites were stabilised with 3% cement content, compacted and cured. The textural properties and shear strength parameters of dry and soaked specimens of the cemented geocomposites were determined by direct shear tests. The shear parameters and slope stability charts were used to simulate the slope of typical road embankments. The settlement potentials at different applied normal stresses were also determined. Inclusion of EPS reduced the dry density of the residual soils from an average value of 1790 kg/m3 to 1335 kg/m3. The maximum friction coefficient, tan ᴓ′, mobilised by the geocomposite specimens decreased with an increase in the soil fines content (>0.425 mm. The difference in tan ᴓ′ between the stabilised geocomposites and the natural soil was also dependent on the fines content. For an embankment height of 20 m, slope angles of 38° and 62° were determined for fine sand geocomposites in fully saturated drainage and drained conditions, respectively. Lower slope angles were determined for geocomposites made from silty, coarse and gravelly sands. A limiting embankment height of 50 m was determined for the four geocomposites. Rainfall-induced settlement of geocomposites was dependent on pre-inundation stiffness; for the range of applied stress up to 200 kPa, the settlement exhibited by the fine and silty sand geocomposites was lower than that for the coarse and gravelly sand geocomposites. Fine and silty sands make poor materials for slope embankments because of their poor hydraulic conductivity; however, fine and silty sand geocomposites have a good conductivity and friction angle to support

  20. Good Laboratory Standards for Clinical Next-Generation Sequencing Cancer Panel Tests

    Directory of Open Access Journals (Sweden)

    Jihun Kim

    2017-05-01

    Full Text Available Next-generation sequencing (NGS has recently emerged as an essential component of personalized cancer medicine due to its high throughput and low per-base cost. However, no sufficient guidelines for implementing NGS as a clinical molecular pathology test are established in Korea. To ensure clinical grade quality without inhibiting adoption of NGS, a taskforce team assembled by the Korean Society of Pathologists developed laboratory guidelines for NGS cancer panel testing procedures and requirements for clinical implementation of NGS. This consensus standard proposal consists of two parts: laboratory guidelines and requirements for clinical NGS laboratories. The laboratory guidelines part addressed several important issues across multistep NGS cancer panel tests including choice of gene panel and platform, sample handling, nucleic acid management, sample identity tracking, library preparation, sequencing, analysis and reporting. Requirements for clinical NGS tests were summarized in terms of documentation, validation, quality management, and other required written policies. Together with appropriate pathologist training and international laboratory standards, these laboratory standards would help molecular pathology laboratories to successfully implement NGS cancer panel tests in clinic. In this way, the oncology community would be able to help patients to benefit more from personalized cancer medicine.

  1. Screening for Saponins Using the Blood Hemolysis Test. An Undergraduate Laboratory Experiment.

    Science.gov (United States)

    Sotheeswaran, Subramaniam

    1988-01-01

    Describes an experiment for undergraduate chemistry laboratories involving a chemical found in plants and some sea animals. Discusses collection and identification of material, a hemolysis test, preparation of blood-coated agar plates, and application of samples. (CW)

  2. Laboratory testing and analysis Dorris Dam Modoc National Wildlife Refuge May 24 1991

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This report presents the results of laboratory testing and stability analyses conducted for Dorris Dam located within the Modoc National Wildlife Refuge, Modoc...

  3. 78 FR 60898 - Regulation on Definition and Requirements for a Nationally Recognized Testing Laboratory...

    Science.gov (United States)

    2013-10-02

    ... Occupational Safety and Health Administration Regulation on Definition and Requirements for a Nationally..., ``definition and requirements for a nationally recognized testing laboratory'' (The Regulation). The Regulation... place all submissions, including any personal information provided, in the public docket...

  4. Laboratory testing on infiltration in single synthetic fractures

    Science.gov (United States)

    Cherubini, Claudia; Pastore, Nicola; Li, Jiawei; Giasi, Concetta I.; Li, Ling

    2017-04-01

    An understanding of infiltration phenomena in unsaturated rock fractures is extremely important in many branches of engineering for numerous reasons. Sectors such as the oil, gas and water industries are regularly interacting with water seepage through rock fractures, yet the understanding of the mechanics and behaviour associated with this sort of flow is still incomplete. An apparatus has been set up to test infiltration in single synthetic fractures in both dry and wet conditions. To simulate the two fracture planes, concrete fractures have been moulded from 3D printed fractures with varying geometrical configurations, in order to analyse the influence of aperture and roughness on infiltration. Water flows through the single fractures by means of a hydraulic system composed by an upstream and a downstream reservoir, the latter being subdivided into five equal sections in order to measure the flow rate in each part to detect zones of preferential flow. The fractures have been set at various angles of inclination to investigate the effect of this parameter on infiltration dynamics. The results obtained identified that altering certain fracture parameters and conditions produces relevant effects on the infiltration process through the fractures. The main variables influencing the formation of preferential flow are: the inclination angle of the fracture, the saturation level of the fracture and the mismatch wavelength of the fracture.

  5. [Vasculitic Peripheral Neuropathies: Clinical Features and Diagnostic Laboratory Tests].

    Science.gov (United States)

    Ogata, Katsuhisa

    2016-03-01

    Vasculitic peripheral neuropathy (VPN) occurs due to ischemic changes of peripheral nerves, resulting from a deficit of vascular blood supply due to damaged vasa nervorum leading to vasculitis. VPN usually manifests as sensorimotor or sensory disturbances accompanied by pain, presenting as a type of multiple mononeuropathy, with a scattered distribution in distal limbs. VPN may also present as a mononeuropathy, distal symmetric polyneuropathy, plexopathy, or radiculopathy. The rapidity of VPN is variable, ranging from days to months, with symptoms occasionally changing with the appearance of new lesions. Careful history taking and neurological examination provides an exact diagnosis. The most common cause of VPN is primary vasculitis predominantly affecting small vessels, including vasa nervorum, anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis, and polyarteritis nodosa. Similar vasculitic processes can also result from a systemic collagen disorder or secondary vasculitis. Electrophysiological studies and pathological investigation of biopsied peripheral nerves and muscles are important for diagnosis of vasculitis. Serological tests, including ANCA, are useful for diagnosis of vasculitis. Accurate neurological examinations are essential for diagnosis and evaluation of clinical course.

  6. Laboratory Testing of Demand-Response Enabled Household Appliances

    Energy Technology Data Exchange (ETDEWEB)

    Sparn, B.; Jin, X.; Earle, L.

    2013-10-01

    With the advent of the Advanced Metering Infrastructure (AMI) systems capable of two-way communications between the utility's grid and the building, there has been significant effort in the Automated Home Energy Management (AHEM) industry to develop capabilities that allow residential building systems to respond to utility demand events by temporarily reducing their electricity usage. Major appliance manufacturers are following suit by developing Home Area Network (HAN)-tied appliance suites that can take signals from the home's 'smart meter,' a.k.a. AMI meter, and adjust their run cycles accordingly. There are numerous strategies that can be employed by household appliances to respond to demand-side management opportunities, and they could result in substantial reductions in electricity bills for the residents depending on the pricing structures used by the utilities to incent these types of responses.The first step to quantifying these end effects is to test these systems and their responses in simulated demand-response (DR) conditions while monitoring energy use and overall system performance.

  7. Laboratory Testing of Demand-Response Enabled Household Appliances

    Energy Technology Data Exchange (ETDEWEB)

    Sparn, B. [National Renewable Energy Lab. (NREL), Golden, CO (United States); Jin, X. [National Renewable Energy Lab. (NREL), Golden, CO (United States); Earle, L. [National Renewable Energy Lab. (NREL), Golden, CO (United States)

    2013-10-01

    With the advent of the Advanced Metering Infrastructure (AMI) systems capable of two-way communications between the utility's grid and the building, there has been significant effort in the Automated Home Energy Management (AHEM) industry to develop capabilities that allow residential building systems to respond to utility demand events by temporarily reducing their electricity usage. Major appliance manufacturers are following suit by developing Home Area Network (HAN)-tied appliance suites that can take signals from the home's 'smart meter,' a.k.a. AMI meter, and adjust their run cycles accordingly. There are numerous strategies that can be employed by household appliances to respond to demand-side management opportunities, and they could result in substantial reductions in electricity bills for the residents depending on the pricing structures used by the utilities to incent these types of responses. The first step to quantifying these end effects is to test these systems and their responses in simulated demand-response (DR) conditions while monitoring energy use and overall system performance.

  8. Role of the Venereal Disease Research Laboratory test in the detection of syphilis.

    Science.gov (United States)

    Diggory, P

    1983-02-01

    Of 9733 consecutive serological samples received by Portsmouth and Southampton Public Health Laboratories (PHL) and tested for syphilis, 190 (140 from men and 50 from women) gave positive results. Thirty new cases of syphilis were identified. Most sera were tested initially by both a specific antibody test (the Treponema pallidum haemaglutination (TPHA) test) and a cardiolipin test (the Venereal Disease Research Laboratory (VDRL) test). Among the 14 patients whose sera gave VDRL-positive but TPHA-negative results, 12 sera gave false-positive results. The sera of 90 patients gave TPHA-positive but VDRL-negative results; sera from only seven of these patients gave false-positive results. The VDRL test is very unlikely to identify a new case of syphilis where a TPHA test has failed to do so. The results of the survey suggest that the VDRL test should be withdrawn from initial testing for syphilis except where early primary disease is suspected.

  9. Preliminary Test of Friction disk type turbine for S-CO{sub 2} cycle application

    Energy Technology Data Exchange (ETDEWEB)

    Baik, Seungjoon; Kim, Hyeon Tae; Lee, Jeong Ik [KAIST, Daejeon (Korea, Republic of)

    2016-05-15

    Due to the relatively mild sodium-CO{sub 2} interaction, the S-CO{sub 2} Brayton cycle can reduce the accident consequence compared to the steam Rankine cycle. Also the S-CO{sub 2} power conversion cycle can achieve high efficiency for SFR core thermal condition. Moreover, the S-CO{sub 2} power cycle can reduce the total cycle footprint due to high density of the working fluid. However, the high pressure operating condition and low viscosity of the fluid cause difficulties in designing appropriate seals and multi-stage turbo machineries. To solve the problem for designing turbo machineries in a creative way, KAIST research team tested a friction disk type turbine concept for the S-CO{sub 2} cycle application. In this paper, the investigation of the Tesla turbine and preliminary test results with compressed air are covered. The KAIST research team investigated a friction disk type turbine, named as Tesla turbine, for the S-CO{sub 2} power cycle applications. Due to the robust design of the fiction disk type, the Tesla turbine technology can be utilized not only for S-CO{sub 2} turbo machinery but also for the multi-phase or sludge flow turbo machinery. The preliminary test of lab-scale Tesla turbine with compressed air was conducted. The high pressure vessel was manufactured for the S-CO{sub 2} operating condition. The test will be concentrated on the turbine efficiency measurement under various conditions and development of the design methodology.

  10. Preliminary Design of Large Scale Sodium Thermal-Hydraulic Test Facility

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Tae Ho; Kim, Tae Joon; Eoh, Jae Hyuk; Lee, Hyeong Yeon; Lee, Jae Han; Jeong, Ji Young; Park, Su Ki; Han, Ji Woong; Yoo, Yong Hwan; Lee, Yong Bum [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2009-10-15

    A large scale sodium thermal-hydraulic test facility is being designed for verification of the advanced design concept of the passive decay heat removal circuit (PDRC) in a medium- or large-sized pool-type SFR. In the test, its cooling capability during the long- and short-term periods after the reactor trip will be evaluated, and also the produced experimental data will be utilized for the assessment and verification of the safety and performance analysis codes. Starting with the preliminary design of the test facility this year using KALIMER-600 as a reference reactor, the basic and the detailed designs will be made through 2011-2012 based on the demonstration reactor which is intended to be constructed by 2028 according to a long-term national SFR development plan. The installation is scheduled to be completed by the end of 2013, and the main experiments will commence from 2015 after the startup test in 2014. This paper briefly introduces the preliminary design features which were produced as a first step to assess the appropriateness of the facility design methodology.

  11. A Preliminary Analysis of Reactor Performance Test (LOEP) for a Research Reactor

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Hyeonil; Park, Su-Ki [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2015-10-15

    The final phase of commissioning is reactor performance test, which is to prove the integrated performance and safety of the research reactor at full power with fuel loaded such as neutron power calibration, Control Absorber Rod/Second Shutdown Rod drop time, InC function test, Criticality, Rod worth, Core heat removal with natural mechanism, and so forth. The last test will be safety-related one to assure the result of the safety analysis of the research reactor is marginal enough to be sure about the nuclear safety by showing the reactor satisfies the acceptance criteria of the safety functions such as for reactivity control, maintenance of auxiliaries, reactor pool water inventory control, core heat removal, and confinement isolation. After all, the fuel integrity will be ensured by verifying there is no meaningful change in the radiation levels. To confirm the performance of safety equipment, loss of normal electric power (LOEP), possibly categorized as Anticipated Operational Occurrence (AOO), is selected as a key experiment to figure out how safe the research reactor is before turning over the research reactor to the owner. This paper presents a preliminary analysis of the reactor performance test (LOEP) for a research reactor. The results showed how different the transient between conservative estimate and best estimate will look. Preliminary analyses have shown all probable thermal-hydraulic transient behavior of importance as to opening of flap valve, minimum critical heat flux ratio, the change of flow direction, and important values of thermal-hydraulic parameters.

  12. 20 CFR 404.1519k - Purchase of medical examinations, laboratory tests, and other services.

    Science.gov (United States)

    2010-04-01

    ... psychological examinations, X-rays and laboratory tests (including specialized tests, such as pulmonary function... tests, and other services. 404.1519k Section 404.1519k Employees' Benefits SOCIAL SECURITY... Standards for the Type of Referral and for Report Content § 404.1519k Purchase of medical examinations...

  13. 20 CFR 416.919k - Purchase of medical examinations, laboratory tests, and other services.

    Science.gov (United States)

    2010-04-01

    ... psychological examinations, X-rays and laboratory tests (including specialized tests, such as pulmonary function... tests, and other services. 416.919k Section 416.919k Employees' Benefits SOCIAL SECURITY ADMINISTRATION... for the Type of Referral and for Report Content § 416.919k Purchase of medical examinations...

  14. Laboratory and field tests of corrosion inhibitors for an offshore application

    Energy Technology Data Exchange (ETDEWEB)

    Skjerve, Sofie; Fuhr, Geir Gundersen; Haldogaard, Geir

    2006-03-15

    Statoil started a R and D-project in 2002 where the goal was to implement environmental friendly corrosion control at a Statoil operated oil producing field. In this project the following tasks have been addressed: 1) Reduction of the chemical consumption. 2) Documentation of the discharge level of the corrosion inhibitor. 3) Documentation of the environmental impact. 4) Development of new environmentally friendly acceptable corrosion inhibitors. 5) Laboratory and field testing of new corrosion inhibitors. This paper describes laboratory and field tests of corrosion inhibitors for this project. The field tests were carried out on an offshore oil producing installation in the North Sea. Five corrosion inhibitor suppliers with totally eleven products were taking part in this test. All the products were tested in the laboratory. The four most promising products from the laboratory tests were tested in the field during a fourteen days offshore test. Only one of the tested products gave satisfactory results from the corrosion field test. Corrosion measurements were performed both with a Zero Resistance Ammetry (ZRA) probe installed directly into a flow line and with two side streams units. One side stream unit was connected upstream the test separator and the other unit was connected downstream the test separator. (author) (tk)

  15. Laboratory Tests of the Inverse Square Law of Gravity

    Science.gov (United States)

    Schlamminger, Stephan

    2010-02-01

    Newton's inverse square force law of gravity follows directly from the fact that we live in a 3-dimensional world. For sub-millimeter length scales there may be undiscovered, extra dimensions. Such extra dimensions can be detected with inverse square law tests accessible to torsion balances. I will present an overview of two experiments that are being conducted at the University of Washington to search for gravitational-strength deviations from the inverse square law for extra dimension length scales smaller than 50 micrometers. One experiment is designed to measure the distance dependent force between closely spaced masses, whereas the second experiment is a null experiment and is only sensitive to a deviation from the inverse square law of gravity. The first experiment consists of a torsion pendulum that is suspended above a continuously rotating attractor. The attractor and the pendulum are disks with azimuthal sectors of alternating high and a low density. The torque on the pendulum disk varies as a function of the attractor angle with a 3 degree period. The amplitude of the torque signal is analyzed as a function of the separation between the pendulum and the attractor. The second experiment consists of a plate pendulum that is suspended parallel to a larger vertical plate attractor. The pendulum plate has an internal density asymmetry with a dense inlay on one half facing the attractor and another inlay on the other half on the side away from the attractor. If the inverse square law holds, the gravitational field of the attractor is uniform and the torque on the pendulum is independent of the gap between pendulum and attractor. The attractor position is modulated between a near and far position and the torque difference on the pendulum is recorded and analyzed for a possible inverse square law violation. )

  16. First Total Reflection X-Ray Fluorescence round-robin test of water samples: Preliminary results

    Energy Technology Data Exchange (ETDEWEB)

    Borgese, Laura; Bilo, Fabjola [Chemistry for Technologies Laboratory, University of Brescia, Brescia (Italy); Tsuji, Kouichi [Graduate School of Engineering, Osaka City University, Osaka (Japan); Fernández-Ruiz, Ramón [Servicio Interdepartamental de Investigación (SIdI), Laboratorio de TXRF, Universidad Autónoma de Madrid, Madrid (Spain); Margui, Eva [Department of Chemistry, University of Girona, Girona (Spain); Streli, Christina [TU Wien, Atominstitut,Radiation Physics, Vienna (Austria); Pepponi, Giancarlo [Fondazione Bruno Kessler, Povo, Trento (Italy); Stosnach, Hagen [Bruker Nano GmbH, Berlin (Germany); Yamada, Takashi [Rigaku Corporation, Takatsuki, Osaka (Japan); Vandenabeele, Peter [Department of Archaeology, Ghent University, Ghent (Belgium); Maina, David M.; Gatari, Michael [Institute of Nuclear Science and Technology, University of Nairobi, Nairobi (Kenya); Shepherd, Keith D.; Towett, Erick K. [World Agroforestry Centre (ICRAF), Nairobi (Kenya); Bennun, Leonardo [Laboratorio de Física Aplicada, Departamento de Física, Universidad de Concepción (Chile); Custo, Graciela; Vasquez, Cristina [Gerencia Química, Laboratorio B025, Centro Atómico Constituyentes, San Martín (Argentina); Depero, Laura E., E-mail: laura.depero@unibs.it [Chemistry for Technologies Laboratory, University of Brescia, Brescia (Italy)

    2014-11-01

    Total Reflection X-Ray Fluorescence (TXRF) is a mature technique to evaluate quantitatively the elemental composition of liquid samples deposited on clean and well polished reflectors. In this paper the results of the first worldwide TXRF round-robin test of water samples, involving 18 laboratories in 10 countries are presented and discussed. The test was performed within the framework of the VAMAS project, interlaboratory comparison of TXRF spectroscopy for environmental analysis, whose aim is to develop guidelines and a standard methodology for biological and environmental analysis by means of the TXRF analytical technique. - Highlights: • The discussion of the first worldwide TXRF round-robin test of water samples (18 laboratories of 10 countries) is reported. • Drinking, waste, and desalinated water samples were tested. • Data dispersion sources were identified: sample concentration, preparation, fitting procedure, and quantification. • The protocol for TXRF analysis of drinking water is proposed.

  17. Preliminary experimental results from the ICARUS test facility at INFN-LNL

    Energy Technology Data Exchange (ETDEWEB)

    Varanini, F. [Dept. of Physics and INFN, University of Padova, via Marzolo 8, 35100 Padova (Italy)

    2009-12-15

    A liquid Argon TPC with a sensitive volume of 27 l has been operated with cosmic rays in the INFN-LNL laboratories. This detector is used to test possible DAQ and trigger solutions for ICARUS and future liquid Argon TPCs.

  18. Preliminary test of the prototype modular cryostat for a 10 MW offshore superconducting wind turbine

    Science.gov (United States)

    Sun, Jiuce; Ramalingam, R.; Sanz, Santiago; Neumann, Holger

    2017-02-01

    The SUPerconducting Reliable lightweight And more POWERful offshore wind turbine (SUPRAPOWER), an EU FP7 funded research project, are under development for an innovative superconducting 10 MW class offshore wind turbine. Due to the requirements of handling, maintenance, reliability of long term and offshore operation, the cryostats are divided in two major parts: the modular cryostat able to accommodate a single coil and a thermal collector that links all the modules. The prototype modular cryostat was designed, manufactured and assembled in Karlsruhe Institute of Technology (KIT). The paper reports preliminary test results of proto-type modular cryostat with a two-stage Gifford-McMahon (GM) cryocooler.

  19. Nonlinear Analysis and Preliminary Testing Results of a Hybrid Wing Body Center Section Test Article

    Science.gov (United States)

    Przekop, Adam; Jegley, Dawn C.; Rouse, Marshall; Lovejoy, Andrew E.; Wu, Hsi-Yung T.

    2015-01-01

    A large test article was recently designed, analyzed, fabricated, and successfully tested up to the representative design ultimate loads to demonstrate that stiffened composite panels with through-the-thickness reinforcement are a viable option for the next generation large transport category aircraft, including non-conventional configurations such as the hybrid wing body. This paper focuses on finite element analysis and test data correlation of the hybrid wing body center section test article under mechanical, pressure and combined load conditions. Good agreement between predictive nonlinear finite element analysis and test data is found. Results indicate that a geometrically nonlinear analysis is needed to accurately capture the behavior of the non-circular pressurized and highly-stressed structure when the design approach permits local buckling.

  20. Development and Preliminary Tests of an Open-Path Airborne Diode Laser Absorption Instrument for Carbon Dioxide

    Science.gov (United States)

    Diskin, Glenn S.; DiGangi, Joshua P.; Yang, Melissa; Slate, Thomas A.; Rana, Mario

    2015-01-01

    Carbon dioxide (CO2) is well known for its importance as an atmospheric greenhouse gas, with many sources and sinks around the globe. Understanding the fluxes of carbon into and out of the atmosphere is a complex and daunting challenge. One tool applied by scientists to measure the vertical flux of CO2 near the surface uses the eddy covariance technique, most often from towers but also from aircraft flying specific patterns over the study area. In this technique, variations of constituents of interest are correlated with fluctuations in the local vertical wind velocity. Measurement requirements are stringent, particularly with regard to precision, sensitivity to small changes, and temporal sampling rate. In addition, many aircraft have limited payload capability, so instrument size, weight, and power consumption are also important considerations. We report on the development and preliminary application of an airborne sensor for the measurement of atmospheric CO2. The instrument, modeled on the successful DLH (Diode Laser Hygrometer) series of instruments, has been tested in the laboratory and on the NASA DC-8 aircraft. Performance parameters such as accuracy, precision, sensitivity, specificity, and temporal response are discussed in the context of typical atmospheric variability and suitability for flux measurement applications. On-aircraft, in-flight data have been obtained and are discussed as well. Performance of the instrument has been promising, and continued flight testing is planned during 2016.

  1. Laboratory Tests of a Handheld X-Ray Fluorescence Spectrometer: A Tool for Planetary Exploration

    Science.gov (United States)

    Young, K. E.; Evans, C. A.; Hodges, K.

    2011-12-01

    Maximizing the science return from a mission to another planetary surface involves the integration of science objectives with deployable technologies that enable the collection of data and samples. For long duration manned missions, it is likely that more samples will be collected than can be returned to Earth due to mass limits. A niche exists for technologies that help prioritize samples for return, provide data for future sample handling and curation, and characterization for samples that are not returned to Earth. To fill this niche, hardware and protocols for field instruments are currently being developed and evaluated at NASA Johnson Space Center and Arizona State University. Our goal is to develop an easily used, environmentally isolated facility as part of the astronaut surface habitat for preliminary sample characterization and down-selection. NASA has constructed a prototype, GeoLab, as a testbed for evaluating the scientific applicability and operational considerations of various analytical instruments. One instrument under evaluation is a small, portable x-ray fluorescence (XRF) spectrometer that can be also be used by astronaut explorers as part of their field gear while on scientific sorties, or on robotic field assistants. We report on preliminary usability tests for commercially available handheld XRF instruments. These instruments collect data by contacting the surface of a rock or sediment sample with an 8 mm-wide sensor window. Within 60 seconds, the devices can provide relatively precise data on the abundance of major and trace elements heavier than Na. Lab-based handheld XRF analyses of terrestrial and lunar samples, compared with those made with full-scale laboratory XRF systems, show good correlation, but we continue to investigate potential sources of error and the need for careful calibration with standards of known composition. Specifically, we use a suite of five terrestrial and five lunar basalts, all well characterized by conventional

  2. Carbon and oxygen isotopic composition of coal and carbon dioxide derived from laboratory coal combustion: A preliminary study

    Science.gov (United States)

    Warwick, Peter; Ruppert, Leslie F.

    2016-01-01

    The concentration of carbon dioxide (CO2) in the atmosphere has dramatically increased from the start of the industrial revolution in the mid-1700s to present levels exceeding 400 ppm. Carbon dioxide derived from fossil fuel combustion is a greenhouse gas and a major contributor to on-going climate change. Carbon and oxygen stable isotope geochemistry is a useful tool to help model and predict the contributions of anthropogenic sources of CO2 in the global carbon cycle. Surprisingly few studies have addressed the carbon and oxygen isotopic composition of CO2 derived from coal combustion. The goal of this study is to document the relationships between the carbon and oxygen isotope signatures of coal and signatures of the CO2 produced from laboratory coal combustion in atmospheric conditions.Six coal samples were selected that represent various geologic ages (Carboniferous to Tertiary) and coal ranks (lignite to bituminous). Duplicate splits of the six coal samples were ignited and partially combusted in the laboratory at atmospheric conditions. The resulting coal-combustion gases were collected and the molecular composition of the collected gases and isotopic analyses of δ13C of CO2, δ13C of CH4, and δ18O of CO2 were analysed by a commercial laboratory. Splits (~ 1 g) of the un-combusted dried ground coal samples were analyzed for δ13C and δ18O by the U.S. Geological Survey Reston Stable Isotope Laboratory.The major findings of this preliminary work indicate that the isotopic signatures of δ13C (relative to the Vienna Pee Dee Belemnite scale, VPDB) of CO2 resulting from coal combustion are similar to the δ13CVPDB signature of the bulk coal (− 28.46 to − 23.86 ‰) and are not similar to atmospheric δ13CVPDB of CO2 (~ − 8 ‰, see http://www.esrl.noaa.gov/gmd/outreach/isotopes/c13tellsus.html). The δ18O values of bulk coal are strongly correlated to the coal dry ash yields and appear to have little or no influence on the δ18O values of CO2

  3. Turkish children's Bender-Gestalt Test performance: a pilot study and preliminary norms.

    Science.gov (United States)

    Ozer, Serap

    2007-12-01

    The present study was undertaken to provide preliminary data for norms on the Bender-Gestalt Test for 253 children ages 5 yr., 5 mo. to 11 yr., 10 mo. in Turkey. The Koppitz Developmental Scoring System gave mean error scores of 4.2 (SD = 3.3) for girls and 3.6 (SD = 3.0) for boys. The mean error scores obtained by all age groups are presented and compared with other cross-cultural data. These scores decreased across age groups, supporting Bender's maturational hypothesis of the test. The present sample performed at a higher developmental level than the Koppitz normative sample for the 5- and 6-year age groups, while means for other age groups were similar to the original U.S. norms. That this pattern is supported in other cross-cultural studies is discussed as well as the importance of developing local norms for visual spatial tests.

  4. Preliminary optical design of an Active Optics test bench for space applications.

    Science.gov (United States)

    Calcines, A.; Bitenc, U.; Rolt, S.; Reeves, S.; Doelman, N.; Human, J.; Morris, T.; Myers, R.; Talbot, G.

    2017-03-01

    This communication presents a preliminary optical design for a test bench conceived within the European Space Agency's TRP project (Active Optics Correction Chain (AOCC) for large monolithic mirrors) with the goal of designing and developing an Active Optics system able to correct in space on telescopes apertures larger than 3 meters. The test bench design uses two deformable mirrors of 37.5 mm and 116 mm, the smallest mirror to generate aberrations and the largest one to correct them. The system is configured as a multi-functional test bench capable of verifying the performance of a Shack-Hartmann wavefront sensor as well as of a Phase Diversity based wavefront sensor. A third optical path leads to a high-order Shack-Hartmann wavefront sensor to monitor the entire system performance.

  5. The NASA Juncture Flow Experiment: Goals, Progress, and Preliminary Testing (Invited)

    Science.gov (United States)

    Rumsey, Christopher L.; Neuhart, Danny H.; Kegerise, Michael A.

    2016-01-01

    NASA has been working toward designing and conducting a juncture flow experiment on a wing-body aircraft configuration. The experiment is planned to provide validation-quality data for CFD that focuses on the onset and progression of a separation bubble near the wing-body juncture trailing edge region. This paper describes the goals and purpose of the experiment. Although currently considered unreliable, preliminary CFD analyses of several different configurations are shown. These configurations have been subsequently tested in a series of "risk-reduction" wind tunnel tests, in order to help down-select to a final configuration that will attain the desired flow behavior. The risk-reduction testing at the higher Reynolds number has not yet been completed (at the time of this writing), but some results from one of the low-Reynolds-number experiments are shown.

  6. Unnecessary repeat requesting of tests: an audit in a government hospital immunology laboratory.

    Science.gov (United States)

    Kwok, J; Jones, B

    2005-05-01

    Unnecessary repeat requesting of tests can make up a large proportion of a laboratory's workload. This audit set out to establish the size of this problem and to identify the circumstances under which these repeat requests were made in a government tertiary hospital immunology laboratory. The numbers of tests for immunoglobulin measurement, common autoantibodies, and tumour markers that were repeated over a 12 month period were analysed by interrogating the Delphic laboratory computer system using a management information system for raw data enquiry protocol. Repeat requests within 12 weeks of a previous request made up 16.78% of the total workload. The total cost of the tests was estimated at 132 151 US dollars. The waste of technician time and reagents as a result of unnecessary repeat testing is excessive. Many of these tests might be eliminated with the use of interventions such as computerised reminders.

  7. Evaluation of a laboratory test to detect resistance to closantel in Haemonchus contortus.

    Science.gov (United States)

    Lloyd, J B; Fitzgibbon, C C; Barchia, I

    2000-10-01

    To evaluate a laboratory test for closantel resistance in Haemonchus contortus. Field isolates of H contortus, known to be resistant to closantel, were tested in the assay. In addition, mixtures of closantel-susceptible and closantel-resistant laboratory reference strains were tested to develop a method of predicting the proportion of resistant worms in a sample from the field. The assay correctly identified as resistant all of the closantel-resistant field isolates of H contortus. It also identified one isolate with an in vivo efficacy of 98% as having emerging resistance. Testing of the mixtures of laboratory reference strains revealed that an isolate would be classified as resistant when it consists of about 25% or more resistant worms. Test samples that are not fully susceptible yet contain less than 25% resistant worms may be classified as emerging resistance. The in vitro migration assay is a sensitive method of detecting closantel resistance in H contortus.

  8. Laboratory Diagnosis of Syphilis: A Survey to Examine the Range of Tests Used in Canada

    Directory of Open Access Journals (Sweden)

    Raymond SW. Tsang

    2011-01-01

    Full Text Available Laboratory diagnosis of syphilis has undergone major changes in the past decade with the introduction of immunoassays and recombinant Treponema pallidum antigens as screening tools for syphilis infection. To address this change in laboratory practice, a national syphilis laboratory working group was established with members from the Public Health Agency of Canada, provincial public health laboratories across the country as well as sexually transmitted infection researchers, clinicians and epidemiologists. This working group aims to examine how the use of newer immunoassays will affect syphilis diagnosis, surveillance and disease management. To provide a baseline for this work, an e-mail survey was conducted in the fall of 2009 to determine current laboratory practices for syphilis diagnosis in Canada. The most commonly used tests were rapid plasma reagin, enzyme immunoassay, T pallidum passive particle agglutination, venereal disease research laboratory, fluorescent treponemal antibody absorption, line immunoassay and polymerase chain reaction with 92%, 36%, 32%, 20%, 12%, 12% and 12% of the responding laboratories reporting using these tests, respectively. The ultimate goal of this working group will be to update laboratory guidelines for the diagnosis of syphilis, and to identify syphilis surveillance and research priorities in Canada.

  9. Laboratory diagnosis of syphilis: A survey to examine the range of tests used in Canada.

    Science.gov (United States)

    Tsang, Raymond Sw; Radons, Sandra Michelle; Morshed, Muhammad

    2011-01-01

    Laboratory diagnosis of syphilis has undergone major changes in the past decade with the introduction of immunoassays and recombinant Treponema pallidum antigens as screening tools for syphilis infection. To address this change in laboratory practice, a national syphilis laboratory working group was established with members from the Public Health Agency of Canada, provincial public health laboratories across the country as well as sexually transmitted infection researchers, clinicians and epidemiologists. This working group aims to examine how the use of newer immunoassays will affect syphilis diagnosis, surveillance and disease management. To provide a baseline for this work, an e-mail survey was conducted in the fall of 2009 to determine current laboratory practices for syphilis diagnosis in Canada. The most commonly used tests were rapid plasma reagin, enzyme immunoassay, T pallidum passive particle agglutination, venereal disease research laboratory, fluorescent treponemal antibody absorption, line immunoassay and polymerase chain reaction with 92%, 36%, 32%, 20%, 12%, 12% and 12% of the responding laboratories reporting using these tests, respectively. The ultimate goal of this working group will be to update laboratory guidelines for the diagnosis of syphilis, and to identify syphilis surveillance and research priorities in Canada.

  10. Laboratory tests in the detection of extended spectrum beta-lactamase production: National Committee for Clinical Laboratory Standards (NCCLS screening test, the E-test, the double disk confirmatory test, and cefoxitin susceptibility testing

    Directory of Open Access Journals (Sweden)

    Pedro A. d'Azevedo

    2004-10-01

    Full Text Available Extended spectrum beta-lactamase (ESBL production by Klebsiella sp. and E. coli is an emerging problem. In this study, 107 clinical isolates (53 E. coli, 47 K. pneumoniae and 7 K. oxytoca screened as ESBL producers by the NCCLS disk diffusion procedure were submitted to a double disk confirmatory test (DDT and to the E-test double strip for confirmation of ESBL production by demonstration of clavulanic acid inhibition effect (CAIE. Only 72/107 (67% of the isolates were confirmed as ESBL producers by DDT, with diverse results among species. By the E-test, 58/107 (54% isolates were confirmed as ESBL producers, and 18/107 (17% were not determinable. Susceptibility to cefoxitin was found in 57/68 (83% of strains that did not show CAIE. ESBL detection remains a controversial issue and clinical laboratories are in need of a simple and effective way to recognize strains with this kind of resistance.

  11. Laboratory Tests

    Science.gov (United States)

    ... specific genetic defects. This is particularly true of Severe Combined Immune Deficiency (SCID) where more than 12 different ... receptors. Looking to the Future Newborn screening for severe T-cell immunodeficiency is now recommended by the Secretary of the ...

  12. Laboratory Tests

    Science.gov (United States)

    ... evaluation of large parts of or the entire genetic code for an individual at relatively low cost. These ... of personalized medicine based on an individual’s unique genetic code, but when this will become reality at a ...

  13. The laboratory test rig with miniature jet engine to research aviation fuels combustion process

    OpenAIRE

    Gawron Bartosz; Białecki Tomasz

    2015-01-01

    This article presents laboratory test rig with a miniature turbojet engine (MiniJETRig – Miniature Jet Engine Test Rig), that was built in the Air Force Institute of Technology. The test rig has been developed for research and development works aimed at modelling and investigating processes and phenomena occurring in full scale jet engines. In the article construction of a test rig is described, with a brief discussion on the functionality of each of its main components. Additionally examples...

  14. Conformity assessment of the measurement accuracy in testing laboratories using a software application

    Science.gov (United States)

    Diniţă, A.

    2017-02-01

    This article presents a method for assessing the accuracy of the measurements obtained at different tests conducted in laboratories by implementing the interlaboratory comparison method (organization, performance and evaluation of measurements of tests on the same or similar items by two or more laboratories under predetermined conditions). The program (independent software application), realised by the author and described in this paper, analyses the measurement accuracy and performance of testing laboratory by comparing the results obtained from different tests, using the modify Youden diagram, helping identify different types of errors that can occur in measurement, according to ISO 13528:2015, Statistical methods for use in proficiency testing by interlaboratory comparison. A case study is presented in the article by determining the chemical composition of identical samples from five different laboratories. The Youden diagram obtained from this study case was used to identify errors in the laboratory testing equipment. This paper was accepted for publication in Proceedings after double peer reviewing process but was not presented at the Conference ROTRIB’16

  15. Preliminary Design Report of Fluid System of PDRC Performance Test Facility

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Tae-Ho; Eoh, Jae-Hyuk; Seong, Seung-Hwan; Han, Ji-Woong; Choi, Byoung-Hae; Kim, Seong-O

    2008-10-15

    PDRC (Passive Decay Heat Removal Circuit) is a safety grade passive residual heat removal system of KALIMER-600. In order to assess the long- and short-term cooling capabilities of PDRC and produce the experimental data for the verification of the performance and safety analysis codes, PDRC performance test was planned for. In this study, the overall design requirements and the preliminary design data for the fluid system of test facility are presented. The fluid system of the facility is composed of the primary heat transport system, the PDRC, the IHX air cooling system and the sodium supply/purification system. The preliminarily designed facility is scaled-down to 1/4 for length, 1/400 for volume from the primary heat transport system and the PDRC of KALIMER-600 based on a reliable scaling method. It can simulate the cooling of primary heat transport system for the full temperature condition in case of the reactor and pump trips. The produced preliminary design data will be used in the future as the basic information for a detailed design, an establishment of experimental requirement and an assessment of the appropriateness of facility design.

  16. 40 CFR 1065.15 - Overview of procedures for laboratory and field testing.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 32 2010-07-01 2010-07-01 false Overview of procedures for laboratory and field testing. 1065.15 Section 1065.15 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR POLLUTION CONTROLS ENGINE-TESTING PROCEDURES Applicability and General Provisions §...

  17. Harmonization of antimicrobial susceptibility testing among veterinary diagnostic laboratories in the five Nordic countries

    DEFF Research Database (Denmark)

    Petersen, A.; Aarestrup, Frank Møller; Hofshagen, Merete

    2003-01-01

    , whereas for Enterococcus spp., two laboratories had less than 90 % concordant results. Susceptibility testing of Salmonella to fluoroquinolones gave rise to almost 0.5% nonconcordant results and susceptibility testing of S. aureus to vancomycin resulted in that 1.8% of the strains were incorrectly...

  18. Laboratory and field testing for utilization of an excavated soil as landfill liner material.

    Science.gov (United States)

    Bozbey, Ilknur; Guler, Erol

    2006-01-01

    This study investigates the feasibility of using a silty soil excavated in highway construction as landfill liner material. The tests were conducted both at laboratory and in situ scales, and the soil was tested in pure and lime treated forms. Different levels of compaction energy were used. For the field study, a test pad was constructed and in situ hydraulic conductivity experiments were conducted by sealed double ring infiltrometers (SDRI). Laboratory testing revealed that while lime treatment improved the shear strength, it resulted in higher hydraulic conductivity values compared to pure soil. It was observed that leachate permeation did not change the hydraulic conductivity of the pure and lime treated samples. Laboratory hydraulic conductivities were on the order of 10(-9) m/s and met the 1.0E-08 m/s criterion in the Turkish regulations, which is one order of magnitude higher than the value allowed in most developed countries. SDRI testing, which lasted for 6 mo, indicated that lime treatment increased the hydraulic conductivity of pure soil significantly in the field scale tests. In situ hydraulic conductivities were on the order of 1E-08 and 1E-07 m/s, and exceeded the allowable value in the Turkish regulations. Undisturbed samples collected from the test pad were not representative of field hydraulic conductivities. Contrary to laboratory findings, higher compaction efforts did not result in lower hydraulic conductivities in field scales. The study verified the importance of in situ hydraulic conductivity testing in compacted liners.

  19. The Cleveland Sorting Test: a preliminary study of an alternate form of the Wisconsin Card-Sorting Test.

    Science.gov (United States)

    Poreh, Amir; Pastel, Dan; Miller, Ashley; Levin, Jennifer

    2012-01-01

    During the past two decades, studies have repeatedly shown that the Wisconsin Card-Sorting Test (WCST) is not as sensitive to prefrontal-lobe functioning as was originally suspected. Specifically, both clinical and brain-imaging studies have shown that several distinct neural circuits contribute to one's ability to successfully complete different aspects of the test. Another limitation of the WCST is its length, which makes it difficult and frustrating for certain clinical populations. To address the above limitations, researchers have proposed the development of new indexes and the integration of an adaptive testing approach that will allow for the premature termination of the test. Unfortunately, given the proprietary nature of the WCST, none of the above recommendations have been adopted. The present preliminary study examined an alternate form of the 64-Item WCST (WCST-64), the Cleveland Sorting Test (CST-64). The normative data of the two measures as well as the total number of errors, perseverative responses, perseverative errors, and categories completed were compared using a repeated-measures design. Overall, the study supports psychometric approximation of the CST-64 and the WCST-64. Suggestions for future studies and modifications of the CST-64, including the use of recently proposed indexes and adaptive administration approaches, are provided.

  20. The effect of a test ordering software intervention on the prescription of unnecessary laboratory tests - a randomized controlled trial.

    Science.gov (United States)

    Martins, Carlos Manuel Silva; da Costa Teixeira, Andreia Sofia; de Azevedo, Luís Filipe Ribeiro; Sá, Luísa Maria Barbosa; Santos, Paulo Alexandre Azevedo Pereira; do Couto, Maria Luciana Gomes Domingues; da Costa Pereira, Altamiro Manuel Rodrigues; Hespanhol, Alberto Augusto Oliveira Pinto; da Costa Santos, Cristina Maria Nogueira

    2017-02-20

    The way software for electronic health records and laboratory tests ordering systems are designed may influence physicians' prescription. A randomised controlled trial was performed to measure the impact of a diagnostic and laboratory tests ordering system software modification. Participants were family physicians working and prescribing diagnostic and laboratory tests. The intervention group had a modified software with a basic shortcut menu changes, where some tests were withdrawn or added, and with the implementation of an evidence-based decision support based on United States Preventive Services Task Force (USPSTF) recommendations. This intervention group was compared with usual software (control group). The outcomes were the number of tests prescribed from those: withdrawn from the basic menu; added to the basic menu; marked with green dots (USPSTF's grade A and B); and marked with red dots (USPSTF's grade D). Comparing the monthly average number of tests prescribed before and after the software modification, from those tests that were withdrawn from the basic menu, the control group prescribed 33.8 tests per 100 consultations before and 30.8 after (p = 0075); the intervention group prescribed 31.3 before and 13.9 after (p < 0001). Comparing the tests prescribed between both groups during the intervention, from those tests that were withdrawn from the basic menu, the intervention group prescribed a monthly average of 14.0 vs. 29.3 tests per 100 consultations in the control group (p < 0.001). From those tests that are USPSTF's grade A and B, intervention group prescribed 66.8 vs. 74.1 tests per 100 consultations in the control group (p = 0.070). From those tests categorised as USPSTF grade D, the intervention group prescribed an average of 9.8 vs. 11.8 tests per 100 consultations in the control group (p = 0.003). Removing unnecessary tests from a quick shortcut menu of the diagnosis and laboratory tests ordering system had a significant

  1. In vitro preliminary cytotoxicity testing of vegetal extracts, using colorimetric methods

    Directory of Open Access Journals (Sweden)

    Claudia Patricia Cordero Camacho

    2011-12-01

    Full Text Available To advance in the study of the Colombian vegetal biodiversity, considered as a potential source of pharmacologically active products, the establishment of biological activity evaluation systems is necessary, which allow the detection of active products against pathologies with high social and economical impact, such as cancer. This work describes the implementation of a preliminary in vitro methodology for the determination of potential anticancer activity in vegetal extracts, by cytotoxicity testing upon human tumor cell lines, measuring the cellular mass indirectly with the colorimetric assays of MTT (methyl tetrazolium tiazole reduction and SRB (sulforhodamine Bstaining. HT-29, MCF-7, SiHa and HEp-2 cell lines cultures were adapted, MTT concentration, cellular density and treatment period parameters for the cytotoxicity assay were selected. Cell lines sensitivity to the chemotherapeutic agent Doxorubicin HCl was determined. Colombian vegetal species extracts cytotoxicity was tested and usefulness of the assay as a tool to bioguide the search of active products was evidenced.

  2. Laboratory reporting accuracy of polymerase chain reaction testing for avian polyomavirus.

    Science.gov (United States)

    Fitzgerald, Brenna; Olsen, Geoff; Speer, Brian

    2013-03-01

    Polymerase chain reaction (PCR) assays are available for detection of birds infected with avian polyomavirus (APV). Several laboratories offer this diagnostic assay in the United States, but little information is available regarding assay sensitivity, specificity, and accuracy. In this study, known APV-positive and APV-negative samples (each n = 10, 5 undiluted and 5 diluted) were sent to 5 commercial laboratories. A significant difference in reporting accuracy was found among laboratories, most notably for dilute APV-positive samples. Two out of 5 laboratories provided 100% accurate results, 1 had an accuracy of 90%, and 2 reported 80% and 75% accuracy, respectively. The accuracies of the last 2 laboratories were negatively affected by test sensitivities of 60% and 50%, respectively. These findings show that although accurate results were reported by most laboratories, both false-positive and false-negative results were reported by at least 3 laboratories, and false-negative results reported for dilute APV-positive samples predominated. These study findings illustrate a need for veterinary diagnostic laboratories to institute improved voluntary quality control measures.

  3. The laboratory test rig with miniature jet engine to research aviation fuels combustion process

    Directory of Open Access Journals (Sweden)

    Gawron Bartosz

    2015-12-01

    Full Text Available This article presents laboratory test rig with a miniature turbojet engine (MiniJETRig – Miniature Jet Engine Test Rig, that was built in the Air Force Institute of Technology. The test rig has been developed for research and development works aimed at modelling and investigating processes and phenomena occurring in full scale jet engines. In the article construction of a test rig is described, with a brief discussion on the functionality of each of its main components. Additionally examples of measurement results obtained during the realization of the initial tests have been included, presenting the capabilities of the test rig.

  4. Transferability and inter-laboratory variability assessment of the in vitro bovine oocyte fertilization test.

    Science.gov (United States)

    Tessaro, Irene; Modina, Silvia C; Crotti, Gabriella; Franciosi, Federica; Colleoni, Silvia; Lodde, Valentina; Galli, Cesare; Lazzari, Giovanna; Luciano, Alberto M

    2015-01-01

    The dramatic increase in the number of animals required for reproductive toxicity testing imposes the validation of alternative methods to reduce the use of laboratory animals. As we previously demonstrated for in vitro maturation test of bovine oocytes, the present study describes the transferability assessment and the inter-laboratory variability of an in vitro test able to identify chemical effects during the process of bovine oocyte fertilization. Eight chemicals with well-known toxic properties (benzo[a]pyrene, busulfan, cadmium chloride, cycloheximide, diethylstilbestrol, ketoconazole, methylacetoacetate, mifepristone/RU-486) were tested in two well-trained laboratories. The statistical analysis demonstrated no differences in the EC50 values for each chemical in within (inter-runs) and in between-laboratory variability of the proposed test. We therefore conclude that the bovine in vitro fertilization test could advance toward the validation process as alternative in vitro method and become part of an integrated testing strategy in order to predict chemical hazards on mammalian fertility. Copyright © 2015 Elsevier Inc. All rights reserved.

  5. Bioassay Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — The Bioassay Laboratory is an accredited laboratory capable of conducting standardized and innovative environmental testing in the area of aquatic ecotoxicology. The...

  6. Preliminary PINC(Program for the Inspection of Nickel Alloy Components) RRT(Round Robin Test) - Pressurizer Dissimilar Metal Weld

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Kyung Cho; Kang, Sung Sik; Shin, Ho Sang; Chung, Ku Kab; Song, Myung Ho; Chung, Hae Dong [Korea Institute of Nuclear Safety, Daejeon (Korea, Republic of)

    2009-06-15

    After several damages by PWSCC were found in the world, USNRC and PNNL(Pacific Northwest National Laboratory) started the research on PWSCC under the project name of PINC. The aim of the project was 1) to fabricate representative NDE mock-ups with flaws to simulate PWSCCs, 2) to identify and quantitatively assess NDE methods for accurately detecting, sizing and characterizing PWSCCs, 3) to document the range of locations and morphologies of PWSCCs and 4) to incorporate results with other results of ongoing PWSCC research programs, as appropriate. Korea nuclear industries have also been participating in the project. Thermally and mechanically cracked-four mockups were prepared and phased array and manual ultrasonic testing(UT) techniques were applied. The results and lessons learned from the preliminary RRT are summarized as follows: 1) Korea RRT teams performed the RRT successfully. 2) Crack detection probability of the participating organizations was an average 87%, 80% and 80% respectively. 3) RMS error of the crack sizing showed comparatively good results. 4) The lessons learned may be helpful to perform the PINC RRT and PSI /ISI in Korea in the future.

  7. Extended testing of a general contextual classifier using the massively parallel processor - Preliminary results and test plans. [for thematic mapping

    Science.gov (United States)

    Tilton, J. C.

    1985-01-01

    Earlier encouraging test results of a contextual classifier that combines spatial and spectral information employing a general statistical approach are expanded. The earlier results were of limited meaning because they were produced from small (50-by-50 pixel) data sets. An implementation of the contextual classifier on NASA Goddard's Massively Parallel Processor (MPP) is presented; for the first time the MPP makes feasible the testing of the classifier on large data sets (a 12-hour test on a VAX-11/780 minicomputer now takes 5 minutes on the MPP). The MPP is a Single-Instruction, Multiple Data Stream computer, consisting of 16,384 bit serial microprocessors connected in a 128-by-128 mesh array with each element having data transfer connections with its four nearest neighbors so that the MPP is capable of billions of operations per second. Preliminary results are given (with more expected for the conference) and plans are mentioned for extended testing of the contextual classifier on Thematic Mapper data sets.

  8. Preliminary Multirod Burst Test Program results and implications of interest to reactor safety evaluations

    Energy Technology Data Exchange (ETDEWEB)

    Chapman, R.H. (comp.)

    1978-01-01

    The Multirod Burst Test (MRBT) Program, in progress at Oak Ridge National Laboratory, is investigating LWR cladding deformation in single- and multirod test arrays under conditions representative of reflood and refill phases of a LOCA. In these tests internally pressurized, unirradiated Zircaloy-4 tubes containing electrically heated fuel simulators are tested to failure in a low-pressure, superheated-steam environment. The tubes are ''uniformly'' heated over a 915-mm length; the simulator pressure, due to the small enclosed gas volume, also varies with temperature (and deformation) during the test. Two 4 x 4 multirod tests (B-1 and B-2), one with and one without the shroud being heated, have been conducted with a bundle heating rate of approx. 29/sup 0/C/sec; initial pressure conditions for these tests were selected to cause failure at about 860/sup 0/C. An additional 4 x 4 array (B-3) was tested using a bundle heating rate of approx. 10/sup 0/C/sec; the shroud was also heated in this test. Initial conditions were adjusted to cause failure at approx. 760/sup 0/C. Posttest examination (including flow tests) of the B-1 and B-2 test arrays, is essentially complete, and pertinent data are included in this summary.

  9. Comparative Laboratory-Scale Testing of Dispersant Effectiveness of 23 Crude Oils Using Four Different Testing Protocols

    Science.gov (United States)

    A controlled laboratory study was conducted to measure the dispersion effectiveness of Corexit 9500 on 20 different crude oils. This study was a part of a larger project initiated by the Bureau of Safety and Environmental Enforcement (BSEE) testing 20 oils to compare the predict...

  10. Performance testing of radiobioassay laboratories: In vitro measurements (urinalysis): Final report

    Energy Technology Data Exchange (ETDEWEB)

    MacLellan, J.A.; Traub, R.J.; Fisher, D.R.

    1988-03-01

    This report provides results of the two-round nationwide in vitro bioassay intercomparison study. Conclusions were based on analyses by 35 bioassay laboratories of nearly 1400 artificial urine samples containing known quantities of radionuclides. The test radionuclides were H, /sup 89/Sr, /sup 238/Pu, /sup 241/Am, /sup 137/Cs, /sup 60/Co, and natural uranium. The data reported included background count rates, total samples counts, counting times, counting efficiencies, sample yields, and estimated errrors of the determinations. The measurement data were evaluated according to statistical methods presented in the November 1985 version of the draft ANSI Standard N13.30. If a laboratory failed a performance test for any one of the three criteria, the laboratory was considered to have failed the test for that category. 22 refs., 18 figs., 14 tabs

  11. Testing sediment biological effects with the freshwater amphipod Hyalella azteca: the gap between laboratory and nature.

    Science.gov (United States)

    Wang, Feiyue; Goulet, Richard R; Chapman, Peter M

    2004-12-01

    The freshwater amphipod, Hyalella azteca, is widely used in laboratory sediment toxicity and bioaccumulation tests. However, its responses in the laboratory are probably very different from those in the field. A review of the literature indicates that in its natural habitat this species complex is primarily epibenthic, derives little nutrition from the sediments, and responds primarily to contaminants in the overlying water column (including water and food), not sediment or porewater. In laboratory sediment toxicity tests H. azteca is deprived of natural food sources such as algal communities on or above the sediments, and is subjected to constant light without any cover except that afforded by burial into the sediments. Under these constraining laboratory conditions, H. azteca has been reported to respond to sediment or porewater contamination. In nature, contamination of overlying water from sediment is less likely than in the laboratory because of the large, generally non-static sink of natural surface water. H. azteca does not appear to be the most appropriate test species for direct assessments of the bioavailability and toxicity of sediment contaminants, though it is probably appropriate for testing the toxicity of surface waters. Toxic and non-toxic responses will be highly conservative, though the latter are probably the most persuasive given the exposure constraints. Thus H. azteca is probably a suitable surrogate species for determining sediments that are likely not toxic to field populations; however, it is not suitable for determining sediments that are likely toxic to field populations.

  12. The changing face of hemostasis testing in modern laboratories: consolidation, automation, and beyond.

    Science.gov (United States)

    Lippi, Giuseppe; Plebani, Mario; Favaloro, Emmanuel J

    2015-04-01

    The reality of laboratory diagnostics as a whole, and hemostasis testing in particular, is evolving under new paradigms of efficiency. The driving forces of health care and laboratory diagnostics in the third millennium are mainly represented by macro- and microeconomics. In a world with limited resources, shattered by an unprecedented economic crisis, laboratory diagnostics is undergoing a substantial reorganization, with emergence of new models under the imperative of terms, such as bedside testing, consolidation, and networking. The paradigms under which these changes are being developed include a variety of environment, preanalytical, technological, professional, and health-care aspects. The maintenance of continued quality is indeed the major challenge to be faced in the foreseeable future. In fact, some challenges prepotently emerge during a consolidation process, which basically involve delayed testing, centrifugation, transportation, and stability of the specimens, as well as the potential mismatch of sample matrix. This article is aimed to provide an overview of the current economic scenario of laboratory diagnostics and discuss the changing face of hemostasis testing in modern laboratories, providing a synthetic overview about potential drawbacks of actualized solutions.

  13. Preliminary Status Report of Neutron Radiation Effects and Damage to Neutron Imaging System Equipment at Lawrence Livermore National Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Bleuel, D. L. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Anderson, S. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Bernstein, L. A. [Univ. of California, Berkeley, CA (United States); Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Brand, C. A. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Brown, J. A. [Univ. of California, Berkeley, CA (United States); Caggiano, J. A. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); FItsos, P. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Goldblum, B. L. [Univ. of California, Berkeley, CA (United States); Hall, J. M. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Harrig, K. P. [Univ. of California, Berkeley, CA (United States); Johnson, M. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Kruse, L. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Laplace, T. A. [Univ. of California, Berkeley, CA (United States); Mahowald, M. [Univ. of California, Berkeley, CA (United States); Matthews, E. [Univ. of California, Berkeley, CA (United States); Nielson, D. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Ratkiewicz, A. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Rusnak, B. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Souza, R. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Ureche, A. [Univ. of California, Berkeley, CA (United States); Ummel, C. [Univ. of California, Berkeley, CA (United States); Wiedrick, A. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Zeiser, F. [Univ. of Oslo (Norway)

    2017-02-08

    A high-intensity neutron source is being constructed at Lawrence Livermore National Laboratory (LLNL) to perform neutron imaging (NI). Two accelerators are be- ing installed in the shielded, underground, north cave of Building 194 to produce neutrons via deuterium- deuterium fusion at 4 MeV or 7 MeV in a windowless gas cell. Over months to years of future experiments, elec- tronic and mechanical equipment in the room will be ir- radiated by a large uence of neutrons, which could cause them to fail or function incorrectly. Neutrons will also activate equipment and materials in the room, making frequent maintenance di cult and time-consuming, ex- acerbating the consequence of equipment failure. To test the neutron response and failure probability of mission- critical components, a variety of equipment intended to be located closest to the neutron source was irradiated at Lawrence Berkeley National Laboratory's (LBNL's) 88-inch cyclotron, using neutrons produced from the breakup of deuterons impinging a thick beryllium target. The high neutron production and high neutron energy of this reaction in combination with the close-in geom- etry possible at the cyclotron allows the application of neutron doses expected to be delivered in months of NI facility operation in only a few days. In most cases, each piece of equipment was irradiated while powered, moni- tored remotely for failure, to test both its live response to irradiation in addition to permanent e ects. Aluminum activation foils were used as uence monitors, assuming the spectral shape measured by Meulders et. al.[1] While the neutron spectrum of the NI facility and the LBNL fa- cility were not identical, relative electronics and materials damage cross sections were used to equate an equivalent amount of energy-dependent neutron damage.

  14. Preliminary study of an immunochromatography test for serological diagnosis of canine brucellosis.

    Science.gov (United States)

    Wanke, M M; Cairó, F; Rossano, M; Laiño, M; Baldi, P C; Monachesi, N E; Comercio, E A; Vivot, M M

    2012-12-01

    The most widely used screening test for the diagnosis of brucellosis in the dog is the rapid slide agglutination test in the presence of 2-mercaptoethanol (2ME-RSAT). The diagnosis is partially confirmed by the agar gel immunodiffusion test (AGID) and definitively confirmed by bacteriological isolation. Some chronic cases not detected by these tests may be detected by ELISA tests. The use of 2ME-RSAT in routine clinical practice requires a microscope and an experienced operator. An immunochromatographic diagnostic test for canine brucellosis (FASTest(®) Brucella c., Megacor, Hörbranz, Austria) has been recently released. In this study, we compared the diagnostic performance of the FASTest with those of 2ME-RSAT, AGID and ELISAs. Sera from 17 healthy dogs used as negative controls yielded negative results by FASTest, indicating a 100% specificity in this sample. Among 27 sera of dogs with acute or subacute brucellosis confirmed by B. canis isolation, all of which were positive by RSAT and ELISAs, the FASTest was positive in 24 cases and AGID in 23. In acute and subacute cases, the sensitivity of FASTest was 89%. Sera from six dogs with bacteriologically confirmed chronic brucellosis, which were positive by ELISAs but negative by 2ME-RSAT, were also tested; 1 was positive by FASTest and 4 were positive by AGID. These preliminary results indicate a good specificity of the FASTest (100% in this sample) but an unacceptable sensitivity as a screening test. In cases with chronic brucellosis, the sensitivity of the FASTest was lower than that of ELISAs but this assay could make a good intermediate test to be run after a positive RSAT and before running an AGID.

  15. Laboratory tests to assess patients with rheumatoid arthritis: advantages and limitations.

    Science.gov (United States)

    Pincus, Theodore; Sokka, Tuulikki

    2009-11-01

    Laboratory tests provide the most definitive information for diagnosing and managing many diseases, and most patients look to laboratory tests as the most important information from a medical visit. Most patients who have rheumatoid arthritis (RA) have a positive test for rheumatoid factor and anticyclic citrullinated peptide (anti-CCP) antibodies, as well as an elevated erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP). More than 30% 40% of patients with RA, however, have negative tests for rheumatoid factor or anti-CCP antibodies or a normal ESR or CRP. More than 30% of patients with RA, however, have negative tests for rheumatoid factor or anti-CCP antibodies, and 40% have a normal ESR or CRP. These observations indicate that, although they can be helpful to monitor certain patients, laboratory measures cannot serve as a gold standard for diagnosis and management in all individual patients with RA or any rheumatic disease. Physicians and patients would benefit from an improved understanding of the limitations of laboratory tests in diagnosis and management of patients with RA.

  16. Validating a dance-specific screening test for balance: preliminary results from multisite testing.

    Science.gov (United States)

    Batson, Glenna

    2010-09-01

    Few dance-specific screening tools adequately capture balance. The aim of this study was to administer and modify the Star Excursion Balance Test (oSEBT) to examine its utility as a balance screen for dancers. The oSEBT involves standing on one leg while lightly targeting with the opposite foot to the farthest distance along eight spokes of a star-shaped grid. This task simulates dance in the spatial pattern and movement quality of the gesturing limb. The oSEBT was validated for distance on athletes with history of ankle sprain. Thirty-three dancers (age 20.1 +/- 1.4 yrs) participated from two contemporary dance conservatories (UK and US), with or without a history of lower extremity injury. Dancers were verbally instructed (without physical demonstration) to execute the oSEBT and four modifications (mSEBT): timed (speed), timed with cognitive interference (answering questions aloud), and sensory disadvantaging (foam mat). Stepping strategies were tracked and performance strategies video-recorded. Unlike the oSEBT results, distances reached were not significant statistically (p = 0.05) or descriptively (i.e., shorter) for either group. Performance styles varied widely, despite sample homogeneity and instructions to control for strategy. Descriptive analysis of mSEBT showed an increased number of near-falls and decreased timing on the injured limb. Dancers appeared to employ variable strategies to keep balance during this test. Quantitative analysis is warranted to define balance strategies for further validation of SEBT modifications to determine its utility as a balance screening tool.

  17. Point-Counterpoint: The FDA Has a Role in Regulation of Laboratory-Developed Tests.

    Science.gov (United States)

    Caliendo, Angela M; Hanson, Kimberly E

    2016-04-01

    Since the Food and Drug Administration (FDA) released its draft guidance on the regulation of laboratory-developed tests (LDTs) in October 2014, there has been a flurry of responses from commercial and hospital-based laboratory directors, clinicians, professional organizations, and diagnostic companies. The FDA defines an LDT as an "in vitrodiagnostic device that is intended for clinical use and is designed, manufactured, and used within a single laboratory." The draft guidance outlines a risk-based approach, with oversight of high-risk and moderate-risk tests being phased in over 9 years. High-risk tests would be regulated first and require premarket approval. Subsequently, moderate-risk tests would require a 510(k) premarket submission to the FDA and low-risk tests would need only to be registered. Oversight discretion would be exercised for LDTs focused on rare diseases (defined as fewer than 4,000 tests, not cases, per year nationally) and unmet clinical needs (defined as those tests for which there is no alternative FDA-cleared or -approved test). There was an open comment period followed by a public hearing in early January of 2015, and we are currently awaiting the final decision regarding the regulation of LDTs. Given that LDTs have been developed by many laboratories and are essential for the diagnosis and monitoring of an array of infectious diseases, changes in their regulation will have far-reaching implications for clinical microbiology laboratories. In this Point-Counterpoint, Angela Caliendo discusses the potential benefits of the FDA guidance for LDTs whereas Kim Hanson discusses the concerns associated with implementing the guidance and why these regulations may not improve clinical care.

  18. First Total Reflection X-Ray Fluorescence round-robin test of water samples: Preliminary results

    Science.gov (United States)

    Borgese, Laura; Bilo, Fabjola; Tsuji, Kouichi; Fernández-Ruiz, Ramón; Margui, Eva; Streli, Christina; Pepponi, Giancarlo; Stosnach, Hagen; Yamada, Takashi; Vandenabeele, Peter; Maina, David M.; Gatari, Michael; Shepherd, Keith D.; Towett, Erick K.; Bennun, Leonardo; Custo, Graciela; Vasquez, Cristina; Depero, Laura E.

    2014-11-01

    Total Reflection X-Ray Fluorescence (TXRF) is a mature technique to evaluate quantitatively the elemental composition of liquid samples deposited on clean and well polished reflectors. In this paper the results of the first worldwide TXRF round-robin test of water samples, involving 18 laboratories in 10 countries are presented and discussed. The test was performed within the framework of the VAMAS project, interlaboratory comparison of TXRF spectroscopy for environmental analysis, whose aim is to develop guidelines and a standard methodology for biological and environmental analysis by means of the TXRF analytical technique.

  19. Preliminary study fo the interference of proteic compounds of radiopharmaceuticals in the test of lisadode amebocitos de limulus (LAL)

    CERN Document Server

    Aldana, C

    1997-01-01

    In this thesis the objective was evaluate the interference of proteic compounds of the radiopharmaceuticals in the test LAL (lisado of amebocitos de limulus) for this, macroagregates of albumina (MAA) was used with metilendifosfonato (MDP) as control that is the radiopharmaceutical more used in the nuclear medicine centers of the country. Initially preliminary test were carried out to assess if some of two radiopharmaceuticals would cause interference with LAL test, after the test was validated and finally routine tests were made. With the preliminary assays was concluded that proteic compounds did not cause interference (albumina with a concentration of 2 md/dl) with the MAA. However with the MDP cause interference with LAL test. The interference was eliminated with a dilution of 1:8 of the sample. Was concluded that the success of LAL test depends on conditions such as temperature, pH, constant incubation (no minimum variations) and that is a good test for quality control of the radiopharmaceuticals.

  20. Radiation Testing at Sandia National Laboratories: Sandia – JPL Collaboration for Europa Lander

    Energy Technology Data Exchange (ETDEWEB)

    Hattar, Khalid Mikhiel [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States). Ion Beam Lab.; Olszewska-Wasiolek, Maryla Aleksandra [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States). Gamma Irradiation Facility

    2017-01-01

    Sandia National Laboratories (SNL) is assisting Jet Propulsion Laboratory in undertaking feasibility studies and performance assessments for the Planetary Protection aspect of the Europa Lander mission. The specific areas of interest for this project are described by task number. This white paper presents the evaluation results for Task 2, Radiation Testing, which was stated as follows: Survey SNL facilities and capabilities for simulating the Europan radiation environment and assess suitability for: A. Testing batteries, electronics, and other component and subsystems B. Exposing biological organisms to assess their survivability metrics.

  1. Laboratory testing of TiB/sub 2/-based cathodes for electrolytic production of aluminum

    Energy Technology Data Exchange (ETDEWEB)

    Schilling, C.H.

    1988-07-01

    Experimental research was performed to evaluate TiB/sub 2/-based cathodes, which may be used for retrofitting existing commercial Hall-Heroult cells. Candidate cathode materials and retrofit designs were analyzed in laboratory-scale electrolysis tests and nonpolarized immersion tests in molten Al. The cathode materials and cathode attachment designs were selected based on a literature review (Schilling, Hagen, and Hart 1987) and previous experimental research at the Pacific Northwest Laboratory (Hart et al. 1987). 40 refs., 16 figs., 2 tabs.

  2. Preliminary tests in skull pediatric phantom for dosimetry in computerized tomography; Testes preliminares em um simulador pediatrico de cranio para dosimetria em tomografia computadorizada

    Energy Technology Data Exchange (ETDEWEB)

    Martins, Elaine Wirney; Potiens, Maria da Penha de A., E-mail: elainewirney@uso.br, E-mail: mppalbu@ipen.br [Instituto de Pesquisas Energeticas e Nucleares (IPEN/CNEN-SP), Sao Paulo, SP (Brazil)

    2014-07-01

    Computed tomography (CT) is one of the techniques in the field of radiology with striking technological advance in recent years. One reason for this was the increased number of channels associated with the increased power of the X-ray tube. These conditions allowed the equipment high speed in the acquisition of the cuts, reducing the patient exposure time essential characteristic for the increase of its use in pediatric patients. In this context, were developed a new pediatric skull simulator to analyze the results of measurements performed in laboratory and clinic beams with the objective of creation and use of diagnostic reference levels observing risks stochastic effects and assessing the reduction of absorbed doses in patients undergoing growing. Preliminary tests performed in clinical beams showed C{sub w} values: 2.525 ± 0.212 mGy for the developed simulator quoted and 3.362 ± 0.282 mGy for a simulator developed by IPEN called standard, both being between uncertainty values of 8.4% and 14.4% suggested by TRS number 457.

  3. Multi-laboratory testing of a screening method for world trade center (WTC) collapse dust.

    Science.gov (United States)

    Rosati, Jacky A; Bern, Amy M; Willis, Robert D; Blanchard, Fredrick T; Conner, Teri L; Kahn, Henry D; Friedman, David

    2008-02-15

    The September 11, 2001 attack on the World Trade Center (WTC) covered a large area of downtown New York City with dust and debris. This paper describes the testing of an analytical method designed to evaluate whether sampled dust contains dust that may have originated from the collapse of the WTC. Using dust samples collected from locations affected and not affected (referred to as 'background' locations) by the collapse, a scanning electron microscopy (SEM) analysis method was developed to screen for three materials that are believed to be present in large quantities in WTC dusts: slag wool, concrete, and gypsum. An inter-laboratory evaluation of the method was implemented by having eight laboratories analyze a number of 'blind' dust samples, consisting of confirmed background dust and confirmed background dust spiked with varying amounts of dust affected by the WTC collapse. The levels of gypsum and concrete in the spiked samples were indistinguishable from the levels in the background samples. Measurements of slag wool in dust demonstrated potential for distinguishing between spiked and background samples in spite of considerable within and between laboratory variability. Slag wool measurements appear to be sufficiently sensitive to distinguish dust spiked with 5% WTC-affected dust from 22 out of 25 background dust samples. Additional development work and inter-laboratory testing of the slag wool component will be necessary to improve the precision and accuracy of the method and reduce inter- and intra-laboratory variability from levels observed in the inter-laboratory evaluation.

  4. Establishing benchmarks and metrics for disruptive technologies, inappropriate and obsolete tests in the clinical laboratory.

    Science.gov (United States)

    Kiechle, Frederick L; Arcenas, Rodney C; Rogers, Linda C

    2014-01-01

    Benchmarks and metrics related to laboratory test utilization are based on evidence-based medical literature that may suffer from a positive publication bias. Guidelines are only as good as the data reviewed to create them. Disruptive technologies require time for appropriate use to be established before utilization review will be meaningful. Metrics include monitoring the use of obsolete tests and the inappropriate use of lab tests. Test utilization by clients in a hospital outreach program can be used to monitor the impact of new clients on lab workload. A multi-disciplinary laboratory utilization committee is the most effective tool for modifying bad habits, and reviewing and approving new tests for the lab formulary or by sending them out to a reference lab. Copyright © 2013 Elsevier B.V. All rights reserved.

  5. Pre-operative laboratory testing: A prospective study on comparison and cost analysis

    Directory of Open Access Journals (Sweden)

    Venkatesh H Keshavan

    2016-01-01

    Full Text Available Background and Aims : Pre-operative investigations are performed before any surgical intervention under anaesthesia. Many are considered as routine. However, there are no clear guidelines regarding these in India. We aim to look at the relevance of the laboratory investigations ordered routinely and their cost implications compared with the National Institute of Clinical Excellence (NICE guidelines. Methods: This prospective study was carried out at a tertiary care hospital. A total of 163 patients scheduled for elective surgical procedures were included in this study. Neither the surgeons nor anaesthesiologists involved in the case were aware of the study. The laboratory investigations of the patients who underwent surgery were noted. All values were categorised as normal or abnormal and they were assessed as indicated or unindicated based on NICE guidelines. Results: One hundred and sixty-three patients were subjected to a total of 984 tests. Forty three patients (26% were subjected to tests as per NICE guidelines. Of the 984 tests, 515 tests were unindicated (52%. Out of the 515 unindicated tests, 7 (1.3% were abnormal. None of these seven tests required any intervention or change of anaesthetic plan. The most common unindicated tests done were cardiac echocardiography and chest X-ray (92.5% and 93% respectively. The additional cost incurred towards unindicated tests was 63% of the total cost for the tests. Conclusion: Pre-operative laboratory investigations add to cost significantly. Patient premorbid conditions and surgical grade should guide the clinician to request for the relevant laboratory tests.

  6. Preliminary risk assessment of the Mexican Spotted Owl under a spatially-weighted foraging regime at the Los Alamos National Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Gallegos, A.F.; Gonzales, G.J.; Bennett, K.D.; Pratt, L.E.

    1997-02-01

    The Record of Decision on the Dual Axis Radiographic Hydrodynamic Test Facility at the Los Alamos National Laboratory requires that the Department of Energy takes special precautions to protect the Mexican Spotted Owl (Strix occidentalis lucida). In order to do so, risk to the owl presented by radiological and nonradiological contaminants must be estimated. A preliminary risk assessment on the Mexican Spotted Owl in two Ecological Exposure Units (EEUs) was performed using a modified Environmental Protection Agency Quotient method, the FORTRAN model ECORSK4, and a geographic information system. Estimated doses to the owl under a spatially-weighted foraging regime were compared against toxicological reference doses generating hazard indices (HIs) and hazard quotients (HQs) for three risk source types. The average HI was 0.20 for EEU-21 and 0.0015 for EEU-40. Under the risk parameter assumptions made, hazard quotient results indicated no unacceptable risk to the owl, including a measure of cumulative effects from multiple contaminants that assumes a linear additive toxicity type. An HI of 1.0 was used as the evaluative criteria for determining the acceptability of risk. This value was exceeded (1.06) in only one of 200 simulated potential nest sites. Cesium-137, Ni, {sup 239}Pu, Al and {sup 234}U we`re among the constituents with the highest partial HQs. Improving model realism by weighting simulated owl foraging based on distance from potential nest sites decreased the estimated risk by 72% (0.5 HI units) for EEU-21 and by 97.6% (6.3E-02 HI units) for EEU-40. Information on risk by specific geographical location was generated, which can be used to manage contaminated areas, owl habitat, facility siting, and/or facility operations in order to maintain risk from contaminants at acceptably low levels.

  7. Comparison between field and laboratory steam oxidation testing on aluminide coatings on P92

    Energy Technology Data Exchange (ETDEWEB)

    Agueero, A.; Gonzalez, V.; Gutierrez, M. [Instituto Nacional de Tecnica Aeroespacial, Ctra. Ajalvir Km 4, 28850 Torrejon de Ardoz (Spain); Knoedler, R.; Straub, S. [Alstom Power Systems GmbH, Boveristrasse 22, 68309 Mannheim (Germany); Muelas, R. [Ingenieria y Servicios Aeroespaciales, P Pintor Rosales 34, 28008 Madrid (Spain)

    2011-06-15

    Steam oxidation has become an important issue for steam power plants as operating temperatures increase from the current 550 to 600-650 C. For the last 10 years several groups have been carrying out steam oxidation testing of both uncoated substrates and coatings in the laboratory. On the other hand, field testing results are very scarce. In this paper, a comparison of laboratory steam oxidation testing with field test results carried out by Alstom at the Kraftwerk Westfalen power station located in Hamm, Germany will be presented. Both slurry deposited aluminide coatings and uncoated P92 steel have been included in the study. Under steam (atmospheric pressure) and isothermal conditions in the laboratory at 650 C, spallation of oxides formed on ferritic steels occurs after significantly longer time when compared to exposure to real operating conditions. Oxide spallation results in serious damage in steam power plants by obstructing heat exchanger tubes, erosion of valves and turbine blades, etc. Moreover, the thickness of the oxide scales formed under field testing conditions is significantly higher after similar exposure. On the other hand, aluminide coated P92, which exhibit thickness through cracks, have shown to be stable in the laboratory for up to 60 000 h at 650 C under steam, without evidence of crack propagation. However, field test results indicate that some degree of crack propagation occurs but without causing substrate attack up to 21 700 h of exposure. Moreover, the aluminium oxide observed in both laboratory and field tested specimens is different. (Copyright copyright 2011 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim)

  8. Preliminary piping layout and integration of European test blanket modules subsystems in ITER CVCS area

    Energy Technology Data Exchange (ETDEWEB)

    Tarallo, Andrea, E-mail: andrea.tarallo@unina.it [CREATE, University of Naples Federico II, DII, P.le Tecchio, 80, 80125 Naples (Italy); Mozzillo, Rocco; Di Gironimo, Giuseppe [CREATE, University of Naples Federico II, DII, P.le Tecchio, 80, 80125 Naples (Italy); Aiello, Antonio; Utili, Marco [ENEA UTIS, C.R. Brasimone, Bacino del Brasimone, I-40032 Camugnano, BO (Italy); Ricapito, Italo [TBM& MD Project, Fusion for Energy, EU Commission, Carrer J. Pla, 2, Building B3, 08019 Barcelona (Spain)

    2015-04-15

    Highlights: • The use of human modeling tools for piping design in view of maintenance is discussed. • A possible preliminary layout for TBM subsystems in CVCS area has been designed with CATIA. • A DHM-based method to quickly check for maintainability of piping systems is suggested. - Abstract: This paper explores a possible integration of some ancillary systems of helium-cooled lithium lead (HCLL) and helium-cooled pebble-bed (HCPB) test blanket modules in ITER CVCS area. Computer-aided design and ergonomics simulation tools have been fundamental not only to define suitable routes for pipes, but also to quickly check for maintainability of equipment and in-line components. In particular, accessibility of equipment and systems has been investigated from the very first stages of the design using digital human models. In some cases, the digital simulations have resulted in changes in the initial space reservations.

  9. Preliminary safety evaluation (PSE) for Sodium Storage Facility at the Fast Flux Test Facility

    Energy Technology Data Exchange (ETDEWEB)

    Bowman, B.R.

    1994-09-30

    This evaluation was performed for the Sodium Storage Facility (SSF) which will be constructed at the Fast Flux Test Facility (FFTF) in the area adjacent to the South and West Dump Heat Exchanger (DHX) pits. The purpose of the facility is to allow unloading the sodium from the FFTF plant tanks and piping. The significant conclusion of this Preliminary Safety Evaluation (PSE) is that the only Safety Class 2 components are the four sodium storage tanks and their foundations. The building, because of its imminent risk to the tanks under an earthquake or high winds, will be Safety Class 3/2, which means the building has a Safety Class 3 function with the Safety Class 2 loads of seismic and wind factored into the design.

  10. Developing the Psychological Strain Scales (PSS): Reliability, Validity, and Preliminary Hypothesis Tests.

    Science.gov (United States)

    Zhang, Jie; Lu, Juncheng; Zhao, Sibo; Lamis, Dorian A; Li, Ning; Kong, Yuanyuan; Jia, Cunxian; Zhou, Li; Ma, Zhenyu

    2014-01-01

    Since its inception, the Strain Theory of Suicide has been tested and supported in a number of empirical studies. This social psychological theory can be employed as a complementary conceptualization to account for suicidal behaviors as well as mental disorders. However, the lack of consistent measurements of the strains limits the application of the theory in scientific research. Our research team has developed such scales for future testing of the Strain Theory of Suicide in a more systematic approach. For the initial items to measure the four strains (value, aspiration, deprivation, and coping), we solicited approximately 40 items for each strain with high face validity by about 30 fellow researchers. A preliminary examination of about 160 items for consistency and validity, with a sample of about 300 college students, yielded 20 consistent items for each of the four strain scales. Then, a second study was conducted at a different university with approximately 500 students to further streamline each of the four strain scales and test the validity of each with corresponding established scales and variables. As a result, 15 items were selected for each of the four Psychological Strain Scales (PSS). In correlation and multiple regression analyses, we found support for the hypotheses regarding the positive associations between psychological strains measured by the PSS and psychopathology including suicidal ideation. Follow up research with the new scales needs to be carried out in order to test the effects of psychological strains on suicide and mental disorders for various populations.

  11. Analytical performances of food microbiology laboratories - critical analysis of 7 years of proficiency testing results.

    Science.gov (United States)

    Abdel Massih, M; Planchon, V; Polet, M; Dierick, K; Mahillon, J

    2016-02-01

    Based on the results of 19 food microbiology proficiency testing (PT) schemes, this study aimed to assess the laboratory performances, to highlight the main sources of unsatisfactory analytical results and to suggest areas of improvement. The 2009-2015 results of REQUASUD and IPH PT, involving a total of 48 laboratories, were analysed. On average, the laboratories failed to detect or enumerate foodborne pathogens in 3·0% of the tests. Thanks to a close collaboration with the PT participants, the causes of outliers could be identified in 74% of the cases. The main causes of erroneous PT results were either pre-analytical (handling of the samples, timing of analysis), analytical (unsuitable methods, confusion of samples, errors in colony counting or confirmation) or postanalytical mistakes (calculation and encoding of results). PT schemes are a privileged observation post to highlight analytical problems, which would otherwise remain unnoticed. In this perspective, this comprehensive study of PT results provides insight into the sources of systematic errors encountered during the analyses. This study draws the attention of the laboratories to the main causes of analytical errors and suggests practical solutions to avoid them, in an educational purpose. The observations support the hypothesis that regular participation to PT, when followed by feed-back and appropriate corrective actions, can play a key role in quality improvement and provide more confidence in the laboratory testing results. © 2015 The Society for Applied Microbiology.

  12. Ice Crystal Icing Engine Testing in the NASA Glenn Research Center's Propulsion Systems Laboratory: Altitude Investigation

    Science.gov (United States)

    Oliver, Michael J.

    2014-01-01

    The National Aeronautics and Space Administration (NASA) conducted a full scale ice crystal icing turbofan engine test using an obsolete Allied Signal ALF502-R5 engine in the Propulsion Systems Laboratory (PSL) at NASA Glenn Research Center. The test article used was the exact engine that experienced a loss of power event after the ingestion of ice crystals while operating at high altitude during a 1997 Honeywell flight test campaign investigating the turbofan engine ice crystal icing phenomena. The test plan included test points conducted at the known flight test campaign field event pressure altitude and at various pressure altitudes ranging from low to high throughout the engine operating envelope. The test article experienced a loss of power event at each of the altitudes tested. For each pressure altitude test point conducted the ambient static temperature was predicted using a NASA engine icing risk computer model for the given ambient static pressure while maintaining the engine speed.

  13. Bottom-up laboratory testing of the DKIST Visible Broadband Imager (VBI)

    Science.gov (United States)

    Ferayorni, Andrew; Beard, Andrew; Cole, Wes; Gregory, Scott; Wöeger, Friedrich

    2016-08-01

    The Daniel K. Inouye Solar Telescope (DKIST) is a 4-meter solar observatory under construction at Haleakala, Hawaii [1]. The Visible Broadband Imager (VBI) is a first light instrument that will record images at the highest possible spatial and temporal resolution of the DKIST at a number of scientifically important wavelengths [2]. The VBI is a pathfinder for DKIST instrumentation and a test bed for developing processes and procedures in the areas of unit, systems integration, and user acceptance testing. These test procedures have been developed and repeatedly executed during VBI construction in the lab as part of a "test early and test often" philosophy aimed at identifying and resolving issues early thus saving cost during integration test and commissioning on summit. The VBI team recently completed a bottom up end-to-end system test of the instrument in the lab that allowed the instrument's functionality, performance, and usability to be validated against documented system requirements. The bottom up testing approach includes four levels of testing, each introducing another layer in the control hierarchy that is tested before moving to the next level. First the instrument mechanisms are tested for positioning accuracy and repeatability using a laboratory position-sensing detector (PSD). Second the real-time motion controls are used to drive the mechanisms to verify speed and timing synchronization requirements are being met. Next the high-level software is introduced and the instrument is driven through a series of end-to-end tests that exercise the mechanisms, cameras, and simulated data processing. Finally, user acceptance testing is performed on operational and engineering use cases through the use of the instrument engineering graphical user interface (GUI). In this paper we present the VBI bottom up test plan, procedures, example test cases and tools used, as well as results from test execution in the laboratory. We will also discuss the benefits realized

  14. Semipermeable-membrane devices as an in situ and laboratory testing chamber

    Energy Technology Data Exchange (ETDEWEB)

    Gardiner, W.W.; Word, J.Q. [Battelle, Seqium, WA (United States). Marine Sciences Lab.

    1995-12-31

    The use of semipermeable-membrane devices (SPMDs) to measure the bioavailability of dissolved (< 10{angstrom}) hydrophobic-organic-compounds has recently been established. These low-density polyethylene bags are effective and relatively easy in situ devices for evaluating bioaccumulation potentials of polyaromatic hydrocarbons, pesticides, polychlorinated biphenyls, and dioxins. The authors believe SPMDs may also be effective in situ and laboratory testing chambers for evaluating dissolved contaminant effects on sensitive life stages of freshwater/marine fish and invertebrates. Applications may include dissolved contaminant toxicity of effluents, porewater, water-column, and surface microlayer. In laboratory tests, the applicability of SPMD-testing chambers was explored with marine bivalve larvae (Mytilus galloprovincialis). Test solutions were filtered seawater, dissolved copper, ammonia, and an elutriate preparation that included both organic and inorganic contaminants. SPMDs were filled with seawater, immersed in test solutions for 24-h, then spiked with fertilized M. galloprovincialis embryos. Following 48-h exposures, >90% survival and normal development was observed in the controls, indicating that incubation in the SPMDs did not adversely affect larval development. Incubation in test treatments resulted in slight, but not significantly different, reductions in normal development, relative to the controls. The authors believe longer SPMD immersion prior to testing will likely be required to allow SPMD contents to reach equilibrium with test solutions before eliciting a significant toxicological response. While this may limit the application of SPMDs for short term in situ exposures, they may be used for field/laboratory exposures of a week or more or for collecting equilibrated field samples for laboratory testing.

  15. Laboratory test result interpretation for primary care doctors in South Africa.

    Science.gov (United States)

    Vanker, Naadira; Faull, Norman H B

    2017-01-01

    Challenges and uncertainties with test result interpretation can lead to diagnostic errors. Primary care doctors are at a higher risk than specialists of making these errors, due to the range in complexity and severity of conditions that they encounter. This study aimed to investigate the challenges that primary care doctors face with test result interpretation, and to identify potential countermeasures to address these. A survey was sent out to 7800 primary care doctors in South Africa. Questionnaire themes included doctors' uncertainty with interpreting test results, mechanisms used to overcome this uncertainty, challenges with appropriate result interpretation, and perceived solutions for interpreting results. Of the 552 responses received, the prevalence of challenges with result interpretation was estimated in an average of 17% of diagnostic encounters. The most commonly-reported challenges were not receiving test results in a timely manner (51% of respondents) and previous results not being easily available (37%). When faced with diagnostic uncertainty, 84% of respondents would either follow-up and reassess the patient or discuss the case with a specialist, and 67% would contact a laboratory professional. The most useful test utilisation enablers were found to be: interpretive comments (78% of respondents), published guidelines (74%), and a dedicated laboratory phone line (72%). Primary care doctors acknowledge uncertainty with test result interpretation. Potential countermeasures include the addition of patient-specific interpretive comments, the availability of guidelines or algorithms, and a dedicated laboratory phone line. The benefit of enhanced test result interpretation would reduce diagnostic error rates.

  16. Tests and analyses on the laboratory equipment in fuel-fabrication mockup test facility (Technical Report)

    Energy Technology Data Exchange (ETDEWEB)

    Mishima, T.; Gunji, Y.; Kikumo, H.; Okamoto, N.; Murakami, T.; Sato, S. [Japan Nuclear Cycle Development Inst., Tokai, Ibaraki (Japan). Tokai Works

    1998-11-01

    A rotary press has been manufactured for trial use of fabricating nuclear-fuel pellets, which is compact and superior in processing capacity compared to conventional reciprocating presses, and its performance tests were done. Tests include (1) finding out of problems in the equipment maintenance, (2) a comparative test of rotary and reciprocating presses in pellet fabrication, (3) an injection test of dry-recovered fuel powders, and (4) a confirmation test for process holdup of the fuel powders in the equipment. To evaluate the applicability to MOX (uranium and plutonium mixed oxide) fuel fabrication, 0 - 40 weight % of dry-recovered powders obtained from sintered uranium pellets was added to the raw materials of uranium powders to make the pellets. Some recommendations based on the present testing results in designing large scale MOX fuel fabricating machines are given. (S. Ohno)

  17. Evaluation of the proficiency of trained non-laboratory health staffs and laboratory technicians using a rapid and simple HIV antibody test

    Directory of Open Access Journals (Sweden)

    Mukoyama Yumi

    2005-05-01

    Full Text Available Abstract In Cambodia, nearly half of pregnant women attend antenatal care (ANC, which is an entry point of services for prevention of mother-to-child transmission of HIV (PMTCT. However, most of ANC services are provided in health centres or fields, where laboratory services by technicians are not available. In this study, those voluntary confidential counselling and testing (VCCT counsellors involved in PMTCT were trained by experienced laboratory technicians in our centre on HIV testing using Determine (Abbot Laboratories HIV1/2 test kits through a half-day training course, which consisted of use of a pipette, how to process whole blood samples, and how to read test result. The trained counsellors were midwives working for ANC and delivery ward in our centre without any experience on laboratory works. The objective of this study was to assess the feasibility of the training by evaluating the proficiency of the trained non-laboratory staffs. The trained counsellors withdrew blood sample after pre-test counselling following ANC, and performed the rapid test. Laboratory technicians routinely did the same test and returned reports of the test results to counsellors. Reports by the counsellors and the laboratory technicians were compared, and discordant reports in two groups were re-tested with the same rapid test kit using the same blood sample. Cause of discordance was detected in discussion with both groups. Of 563 blood samples tested by six trained VCCT counsellors and three laboratory technicians, 11 samples (2.0% were reported positive in each group, however four discordant reports (0.7% between the groups were observed, in which two positive reports and two negative reports by the counsellors were negative and positive by the laboratory technicians, respectively. Further investigation confirmed that all the reports by the counsellors were correct, and that human error in writing reports in the laboratory was a cause of these discordant

  18. Reproducibility of pop-ins in laboratory testing of welded joints

    Directory of Open Access Journals (Sweden)

    Berejnoi C.

    2000-01-01

    Full Text Available The pop-in phenomenon, quite common in fracture mechanics tests of welded joints, corresponds to a brittle crack initiation grown from a local brittle zone (LBZ that is arrested in reaching the higher toughness material that surrounds this LBZ. A methodology to obtain a high percentage of pop-in occurrence in laboratory testing is necessary to study the pop-in significance. Such a method is introduced in this work and includes the consumable combination and welding procedures for the SMAW welding process to generate artificial LBZ. In order to find out the influence of the loading state upon the pop-in phenomenon, laboratory CTOD tests were performed using two specimen configurations: some single edge-notched specimens were loaded on a three-point bending (SE(B fixture while others were tested in tensile load (SE(T. A higher frequency of pop-in occurrence was observed in the SE(B geometry.

  19. The financial imperative of physicians to control demand of laboratory testing.

    LENUS (Irish Health Repository)

    Murphy, R K J

    2012-02-01

    It is an integral component of doctor\\'s duty of care to understand the significant impact laboratory testing has on the expense an ultimate quality of healthcare patients receive, yet the costs of these tests are poorly perceived. Utilising semi-structured interviews and questionnaires, we assessed surgeon\\'s perceived costs of two commonly encountered clinical scenarios requiring out of hours laboratory testing. Of the 35 participants only 23.3% (n = 7) accurately estimated the overall cost. The most expensive test was "Type and Screen" at Euro 83, with 77.3% (n = 17) underestimating the cost. Non-consultant hospital doctors qualified for 3 years were more likely to underestimate on-call costs (p = 0.042). It is of utmost importance to improve the knowledge of all surgeons of the financial implications of investigations. Through education we can potentially reduce un-warranted costs and fulfill our duty of care in the most cost efficient manner.

  20. Radiation Protection Report of the First Hot Test at China Reprocessing and Radiochemistry Laboratory

    Institute of Scientific and Technical Information of China (English)

    BAI; Yang; LIU; Ning; JIAO; Xiao-yan; XU; Xin; MA; Hao-ran; WANG; Xiang-li

    2015-01-01

    The first hot test has been completed at China Reprocessing and Radiochemistry Laboratory in September to December 2015.In order to ensure the safety of personal,facility and environment,security group wrote safety management regulation,drew up the specialized radiation monitoring plan and organized emergency exercise.

  1. Present knowledge about Laboratory Testing of Axial Loading on Suction Caissons

    DEFF Research Database (Denmark)

    Manzotti, E.; Vaitkunaite, Evelina; Ibsen, Lars Bo

    on the structure is resisted by push-pull loads on the vertical axis of each suction caisson. Relevant works where this situation is examined by means of laboratory testing are summarized in this article, then different conclusions are followed by discussion and comparison. In the initial theoretical section...

  2. Laboratory evaluation of the improved tube test detection limits for β ...

    African Journals Online (AJOL)

    Administrator

    Laboratory evaluation of the improved tube test ... method, which could be used for qualitative identification of residues in ... particular commonly utilised in lactating animals (Mandell ... boiled in a waterbath for 10 min before being used in Nutrient agar ... Adulterated samples as well as normal control samples were.

  3. 76 FR 39110 - Medicare Program; Section 3113: The Treatment of Certain Complex Diagnostic Laboratory Tests...

    Science.gov (United States)

    2011-07-05

    ... classified (NOC)'' code but that would otherwise meet the criteria set forth in section 3113 for being a... Procedure Coding System (HCPCS) code other than a not otherwise classified (NOC) code under such Coding... for diagnostic laboratory tests defined in section 3113(a)(2) but currently billed using NOC...

  4. Subjective Evaluation of Clothing Comfort and Their Correlation with Laboratory Test

    Institute of Scientific and Technical Information of China (English)

    刘丽英; 张渭源

    2003-01-01

    A series of polyester, cotton, and polyester/cotton blend fabrics were evaluated in a subjective wear.Subjective trial data were correlated with the results of in-house laboratory tests with the regression methods. Experimental results indicate that clothingcomfort assessment by human perception provides a sound basis for comparison of apparel garments under combined microclimates and human-activity levels of normal.

  5. Bridging the gap between clinical failure and laboratory fracture strength tests using a fractographic approach

    NARCIS (Netherlands)

    Aboushelib, M.N.; Feilzer, A.J.; Kleverlaan, C.J.

    2009-01-01

    Objective: The aim of this study was to analyze and to compare the fracture type and the stress at failure of clinically fractured zirconia-based all ceramic restorations with that of morphologically similar replicas tested in a laboratory setup. Methods: Replicas of the same shape and dimensions we

  6. 77 FR 39501 - Current List of Laboratories and Instrumented Initial Testing Facilities Which Meet Minimum...

    Science.gov (United States)

    2012-07-03

    ... HUMAN SERVICES Substance Abuse and Mental Health Services Administration Current List of Laboratories... Testing for Federal Agencies AGENCY: Substance Abuse and Mental Health Services Administration, HHS... thereafter. This notice is also available on the Internet at http://www.workplace.samhsa.gov and http://www...

  7. 75 FR 67749 - Current List of Laboratories and Instrumented Initial Testing Facilities Which Meet Minimum...

    Science.gov (United States)

    2010-11-03

    ... HUMAN SERVICES Substance Abuse and Mental Health Services Administration Current List of Laboratories... Testing for Federal Agencies AGENCY: Substance Abuse and Mental Health Services Administration, HHS... thereafter. This notice is also available on the Internet at http://www.workplace.samhsa.gov and http://www...

  8. 77 FR 5037 - Current List of Laboratories and Instrumented Initial Testing Facilities Which Meet Minimum...

    Science.gov (United States)

    2012-02-01

    ... HUMAN SERVICES Substance Abuse and Mental Health Services Administration Current List of Laboratories... Testing for Federal Agencies AGENCY: Substance Abuse and Mental Health Services Administration, HHS... thereafter. This notice is also available on the Internet at http://www.workplace.samhsa.gov and http://www...

  9. 76 FR 31969 - Current List of Laboratories and Instrumented Initial Testing Facilities Which Meet Minimum...

    Science.gov (United States)

    2011-06-02

    ... HUMAN SERVICES Substance Abuse and Mental Health Services Administration Current List of Laboratories... Testing for Federal Agencies AGENCY: Substance Abuse and Mental Health Services Administration, HHS... thereafter. This notice is also available on the Internet at http://www.workplace.samhsa.gov and http://www...

  10. Bridging the gap between clinical failure and laboratory fracture strength tests using a fractographic approach

    NARCIS (Netherlands)

    Aboushelib, M.N.; Feilzer, A.J.; Kleverlaan, C.J.

    2009-01-01

    Objective: The aim of this study was to analyze and to compare the fracture type and the stress at failure of clinically fractured zirconia-based all ceramic restorations with that of morphologically similar replicas tested in a laboratory setup. Methods: Replicas of the same shape and dimensions

  11. Design of a laboratory hydraulic device for testing of hydraulic pumps

    Directory of Open Access Journals (Sweden)

    Pavel Máchal

    2013-01-01

    Full Text Available The present contribution deals with solves problem of research of testing device to monitor of hydrostatic pumps durability about dynamic loading under laboratory conditions. When carrying out the design of testing device are based on load characteristics of tractor hydraulic circuit, the individual characteristics of hydraulic components and performed calculations. Load characteristics on the tractors CASE IH Magnum 310, JOHN DEERE 8100, ZETOR FORTERRA 114 41 and Fendt 926 Vario were measured. Design of a hydraulic laboratory device is based on the need for testing new types of hydraulic pumps or various types of hydraulic fluids. When creating of hydraulic device we focused on testing hydraulic pumps used in agricultural and forestry tractors. Proportional pressure control valve is an active member of the hydraulic device, which provides change of a continuous control signal into relative pressure of operating fluid. The advantage of a designed hydraulic system is possibility of simulation of dynamic operating loading, which is obtained by measurement under real conditions, and thereby creates laboratory conditions as close to real conditions as possible. The laboratory device is constructed at the Department of Transport and Handling, Faculty of Engineering, Slovak University of Agriculture in Nitra.

  12. Low-molecular-weight heparin as a multipurpose anticoagulant for laboratory testing.

    Science.gov (United States)

    Kawamoto, T; Hiino, M; Takubo, T; Tatsumi, N

    2000-06-01

    The availability of low-molecular-weight heparin (LMWH) for use as an anti-coagulant for laboratory testing was studied. Hematology and chemistry tests were performed with an automated hematology analyzer and an automated chemistry analyzer, respectively. The results of hematology tests of LMWH-treated blood were similar to those obtained for blood treated with ethylenediaminetetraacetic acid (EDTA)-2K, except for platelet count. The platelet count of LMWH-treated blood was lower than that of EDTA-treated blood, and the decrease in platelet count in the former was due to platelet aggregation. Prothrombin time tests could be performed with plasma prepared from LMWH-treated blood, although with such blood the prothrombin time was prolonged. Chemistry tests could be performed for all 18 parameters. These results suggest that LMWH is a candidate for use for hematology testing (with the exception of platelet count), coagulation testing, and chemistry tests.

  13. Announcement: Guidance for U.S. Laboratory Testing for Zika Virus Infection: Implications for Health Care Providers.

    Science.gov (United States)

    2016-11-25

    CDC has released updated guidance online for U.S. laboratory testing for Zika virus infection. The guidance is available at https://www.cdc.gov/zika/laboratories/lab-guidance.html. Frequently asked questions are addressed at https://www.cdc.gov/zika/laboratories/lab-guidance-faq.html. This guidance updates recommendations for testing of specimens by U.S. laboratories for possible Zika virus infection. Major updates to the guidance with clinical implications for health care providers include the following.

  14. Laboratory leach tests of phosphate/sulfate waste grout and leachate adsorption tests using Hanford sediment

    Energy Technology Data Exchange (ETDEWEB)

    Serne, R.J.; Martin, W.J.; McLaurine, S.B.; Airhart, S.P.; LeGore, V.L.; Treat, R.L.

    1987-12-01

    An assessment of the long-term risks posed by grout disposal at Hanford requires data on the ability of grout to resist leaching of waste species contained in the grout via contact with water that percolates through the ground. Additionally, data are needed on the ability of Hanford sediment (soil) surrounding the grout and concrete vault to retard migration of any wastes released from the grout. This report describes specific laboratory experiments that are producing empirical leach rate data and leachate-sediment adsorption data for Phosphate-Sulfate Waste (PSW) grout. The leach rate and adsorption values serve as inputs to computer codes used to forecast potential risk resulting from the use of ground water containing leached species. In addition, the report discusses other chemical analyses and geochemical computer code calculations that were used to identify mechanisms that control leach rates and adsorption potential. Knowledge of the controlling chemical and physical processes provides technical defensibility for using the empirical laboratory data to extrapolate the performance of the actual grout disposal system to the long time periods of interest. 59 refs., 83 figs., 18 tabs.

  15. Clinical evaluation of children testing positive in screening tests for attention-deficit/hyperactivity disorder: A preliminary report

    Directory of Open Access Journals (Sweden)

    Maria Skounti

    2009-06-01

    Full Text Available Background and Objectives: Screening tests are of great diagnostic value in attention-deficit/hyperactivity disorder (ADHD, however final diagnosis relies on a clinical examination by an expert. The objective of the present study was to clinically evaluate children who had been screened positive for ADHD through both a parent and a teacher questionnaire. Methods: Parent interview and child behavior checklist and clinical assessment were used to confirm the preliminary diagnosis in 42 children aged 8 years, who have been screened positive for ADHD out of 1,708 children, in a large, two-setting screening study conducted in Crete, Greece. Results: The diagnosis of ADHD was confirmed for 31 children (74%. In the remaining 11 children, ADHD manifestations were attributed to other primary disorders. None of the 42 children was classified as lacking symptoms suggesting ADHD. Among the 31 children with confirmed ADHD, only 2 had been diagnosed prior to the screening test. Conclusions: Although clinical evaluation is the golden standard for diagnosis of ADHD, two-setting screening questionnaires by parent and teacher are useful tools in identifying children who need further investigation and intervention.

  16. Cross-cultural effects on IQ test performance: a review and preliminary normative indications on WAIS-III test performance.

    Science.gov (United States)

    Shuttleworth-Edwards, Ann B; Kemp, Ryan D; Rust, Annegret L; Muirhead, Joanne G L; Hartman, Nigel P; Radloff, Sarah E

    2004-10-01

    This article presents a review of cross-cultural influences on Wechsler IQ tests, together with a preliminary investigation into WAIS-III test performance (English administration) for a southern African sample (age range 19-30) stratified for white English first language and black African first language, level and quality of education. ('African language' is the term used to denote the indigenous languages of black populations in southern Africa). A two-way ANOVA revealed highly significant effects for both level and quality of education within the black African first language group. Scores for the white English and black African first language groups with advantaged education were comparable with the US standardization, whereas scores for black African first language participants with disadvantaged education were significantly lower than this. Thus indications from this research are that normative studies should take account of the influential variable of quality of education, in addition to level of education. Alternatively faulty conclusions may be drawn about the effects of ethnicity, with the potential for neuropsychological misdiagnosis.

  17. Laboratory test of a prototype heat storage module based on stable supercooling of sodium acetate trihydrate

    DEFF Research Database (Denmark)

    Dannemand, Mark; Kong, Weiqiang; Fan, Jianhua;

    2015-01-01

    Laboratory test of a long term heat storage module utilizing the principle of stable supercooling of 199.5 kg of sodium acetate water mixture has been carried out. Avoiding phase separation of the incongruently melting salt hydrate by using the extra water principle increased the heat storage...... the supercooled sodium acetate water mixture was 194 kJ/kg of sodium acetate water mixture in the first test cycles dropping to 179 kJ/kg in the later test cycles. Instability of the supercooling occurred when the charging periods were short and in the last test cycles where the tube connecting the module...

  18. Results of Laboratory and Industrial Tests of Periodic-Type Gas Generators

    Science.gov (United States)

    Karp, I. N.; P‧yanykh, K. E.; Antoshchuk, T. A.; Lysenko, A. A.

    2015-05-01

    Results of laboratory and industrial tests of periodic-type gas generators burning various solid biofuels have been presented. The tests were carried out with the aim of obtaining producer gas which could totally or partly replace natural gas in power equipment burning gaseous fuel. The energy and environmental characteristics of a boiler unit burning a mixture of producer gas and natural gas have been assessed.

  19. AN AUTOMATED TESTING NETWORK SYSTEM FOR PAPER LABORATORY BASED ON CAN BUS

    Institute of Scientific and Technical Information of China (English)

    Xianhui Yi; Dongbo Yan; Huanbin Liu; Jigeng Li

    2004-01-01

    This paper presents an automated testing network system for paper laboratory based on CAN bus. The overall architecture, hardware interface and software function are discussed in detail. It is indicated through experiment that the system can collect,analyze and store the test results from the various measuring instruments in the paper lab automatically.The simple, reliable, low-cost measuring automation system will have a prosperous application in the future paper industry.

  20. AN AUTOMATED TESTING NETWORK SYSTEM FOR PAPER LABORATORY BASED ON CAN BUS

    Institute of Scientific and Technical Information of China (English)

    XianhuiYi; DongboYan; HuanbinLi; JigengLi

    2004-01-01

    This paper presents an automated testing network system for paper laboratory based on CAN bus. The overall architecture, hardware interface and software function are discussed in detail. It is indicated through experiment that the system can collect, analyze and store the test results from the various measuring instruments in the paper lab automatically. The simple, reliable, low-cost measuring automation system will have a prosperous application in the future paper industry.

  1. Preliminary Tests Concerning Zero-Valent Iron Efficiency in Inorganic Pollutants Remediation

    Directory of Open Access Journals (Sweden)

    Silvia Fiore

    2009-01-01

    Full Text Available Problem statement: This study was aimed to a preliminary evaluation of the applicability of granular Zero-Valent Iron (ZVI to the on site remediation of groundwater polluted by inorganic contaminants by means of a Permeable Reactive Barrier (PRB. A particular interest was devoted to groundwater impacted by Acid Mine Drainage (AMD that was caused by the oxidation of metal sulphide minerals contained in mine wastes, especially iron disulphide pyrite. Although AMD consequences were particularly evident in surface waters, the percolation through mine wastes may heavily alter the groundwater quality, therefore is particularly important the development of a restrained cost remediation technique for groundwater polluted by AMDs. Approach: In this study the degradation efficiency of Brown size 8/50 ZVI (Peerless Powders and Abrasive Inc., Detroit, US was evaluated performing a leaching column test and analyzing the Oxidation Reduction Potential (ORP, metals, nitrates, chlorides and sulphates profiles along the column. Results: This test allowed simulating the solid-liquid contact characteristic of a real PRB behavior that proved to be a possible solution for the remediation of inorganic pollutants in groundwater. Conclusion: The considered material showed efficiency above 99% in metals removal, although further tests, involving biotic processes and more reducing conditions, are necessary to improve the degradation of sulphates and nitrates.

  2. Comparison of Point-of-Care Versus Laboratory Troponin Testing in an Emergency Department Setting.

    Science.gov (United States)

    Juliano, Michael; Wason, Courtney

    2017-07-01

    There have been concerns regarding troponin results accuracy between point-of-care (POC) testing preformed in an emergency department (ED) setting and laboratory testing. The purpose of this study was to compare the results of cardiac troponin I testing as concerns POC testing and laboratory analysis as a way to show that these results are interchangeable. A retrospective chart review was performed from October 2012 through September 2013 to identify all patients who presented to the ED that received both a POC and laboratory troponin associated with the same blood draw. A total of 189 patients met inclusion criteria. Three laboratory samples were hemolyzed and not available for comparison. Of the remaining 186 samples, when a positive cutoff value of 0.034 ng/mL was used: 37 POC tests were positive and 149 POC tests were negative, sensitivity 0.85 (95% confidence interval [CI] = 0.69-0.94), specificity 0.98 (95% CI = 0.94-0.99), positive predictive value 91.9% (95% CI = 77-97.9%), and negative predictive value 96% (95% CI = 91.1-98.4%). When a POC troponin positive cutoff value of 0.12 ng/mL was used: 20 POC tests were positive and 164 were negative: sensitivity 1.0 (95% CI = 0.8-1.0), specificity 0.99 (95% CI = 0.95-1.0), positive predictive value 91% (95% CI = 69-98.4%), and negative predictive value 100% (95% CI = 97.1-100%). In an ED setting; POC testing is accurate and correlates well with laboratory testing. Considering that the POC analysis takes a fraction of time to yield results, the validity of its data is important. The results of this study show that the POC system is a suitable test for rapid evaluation of patients presenting to the ED. This correlation increased with a higher testing positive cutoff value (0.12 versus 0.034 ng/mL). These data can assist the emergency physician with rapid identification of evidence of cardiac injury and be assured that the results are accurate. POC lab testing should be considered whenever possible to provide the

  3. Preliminary Tests For Development Of A Non-Pertechnetate Analysis Method

    Energy Technology Data Exchange (ETDEWEB)

    Diprete, D. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL); McCabe, D. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL)

    2016-09-28

    The objective of this task was to develop a non-pertechnetate analysis method that 222-S lab could easily implement. The initial scope involved working with 222-S laboratory personnel to adapt the existing Tc analytical method to fractionate the non-pertechnetate and pertechnetate. SRNL then developed and tested a method using commercial sorbents containing Aliquat® 336 to extract the pertechnetate (thereby separating it from non-pertechnetate), followed by oxidation, extraction, and stripping steps, and finally analysis by beta counting and Mass Spectroscopy. Several additional items were partially investigated, including impacts of a 137Cs removal step. The method was initially tested on SRS tank waste samples to determine its viability. Although SRS tank waste does not contain non-pertechnetate, testing with it was useful to investigate the compatibility, separation efficiency, interference removal efficacy, and method sensitivity.

  4. Preliminary Tests For Development Of A Non-Pertechnetate Analysis Method

    Energy Technology Data Exchange (ETDEWEB)

    Diprete, D. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL); McCabe, D. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL)

    2016-09-28

    The objective of this task was to develop a non-pertechnetate analysis method that 222-S lab could easily implement. The initial scope involved working with 222-S laboratory personnel to adapt the existing Tc analytical method to fractionate the non-pertechnetate and pertechnetate. SRNL then developed and tested amethod using commercial sorbents containing Aliquat® 336 to extract the pertechnetate (thereby separating it from non-pertechnetate), followed by oxidation, extraction, and stripping steps, and finally analysis by beta counting and Mass Spectroscopy. Several additional items were partially investigated, including impacts of a 137Cs removal step. The method was initially tested on SRS tank waste samples to determine its viability. Although SRS tank waste does not contain non-pertechnetate, testing with it was useful to investigate the compatibility, separation efficiency, interference removal efficacy, and method sensitivity.

  5. Laboratory testing of the in-well vapor-stripping system

    Energy Technology Data Exchange (ETDEWEB)

    Gilmore, T.J.; Francois, O.

    1996-03-01

    The Volatile organic Compounds-Arid Integrated Demonstration (VOC-Arid ID) was implemented by the US Department of Energy`s (DOE`s) Office of Technology Development to develop and test new technologies for the remediation of organic chemicals in the subsurface. One of the technologies being tested under the VOC-Arid ID is the in-well vapor-stripping system. The in-well vapor-stripping concept was initially proposed by researchers at Stanford University and is currently under development through a collaboration between workers at Stanford University and DOE`s Pacific Northwest National Laboratory. The project to demonstrate the in-well vapor-stripping technology is divided into three phases: (1) conceptual model and computer simulation, (2) laboratory testing, and (3) field demonstration. This report provides the methods and results of the laboratory testing in which a full-scale replica was constructed and tested above ground in a test facility located at DOE`s Hanford Site, Washington. The system is a remediation technology designed to preferentially extract volatile organic compounds (VOCs) from contaminated groundwater by converting them to a vapor phase.

  6. Mounted Smartphones as Measurement and Control Platforms for Motor-Based Laboratory Test-Beds †

    Science.gov (United States)

    Frank, Jared A.; Brill, Anthony; Kapila, Vikram

    2016-01-01

    Laboratory education in science and engineering often entails the use of test-beds equipped with costly peripherals for sensing, acquisition, storage, processing, and control of physical behavior. However, costly peripherals are no longer necessary to obtain precise measurements and achieve stable feedback control of test-beds. With smartphones performing diverse sensing and processing tasks, this study examines the feasibility of mounting smartphones directly to test-beds to exploit their embedded hardware and software in the measurement and control of the test-beds. This approach is a first step towards replacing laboratory-grade peripherals with more compact and affordable smartphone-based platforms, whose interactive user interfaces can engender wider participation and engagement from learners. Demonstrative cases are presented in which the sensing, computation, control, and user interaction with three motor-based test-beds are handled by a mounted smartphone. Results of experiments and simulations are used to validate the feasibility of mounted smartphones as measurement and feedback control platforms for motor-based laboratory test-beds, report the measurement precision and closed-loop performance achieved with such platforms, and address challenges in the development of platforms to maintain system stability. PMID:27556464

  7. Field and laboratory tests on acute toxicity of cadmium to freshwater crayfish

    Energy Technology Data Exchange (ETDEWEB)

    1986-09-01

    Environmental regulatory standards for cadmium (EPA 1980), like those for most pollutants, are based on acute, laboratory toxicity tests of single species. Such tests can be conducted rapidly and inexpensively in comparison to acute or chronic field studies, but their validity has often been questioned. Laboratory-based criteria are subject to two criticisms: (1) chemical and physical conditions differ greatly in degree and variability from laboratory to field, and (2) species are not isolated, but live in an ecosystem of interacting taxa and biofeedback. To investigate the validity of basing field toxicity standards on laboratory data, the authors subjected the freshwater crayfish Orconectes immunis for 96 h to various levels of cadmium in laboratory aquaria and experimental ponds. The study was designed to evaluate in part the first criticism of lab-based criteria. The studies were conducted concurrently with similar short-term experiments on the fathead minnow, Pimephales promelas, and coincided with studies of chronic cadmium stress on fathead minnows in experimental ponds.

  8. Laboratory Scale Seismic Surface Wave Testing for the Determination of Soil Elastic Profiles

    Directory of Open Access Journals (Sweden)

    Aziman Madun

    2012-10-01

    Full Text Available Seismic surface wave testing is well-adapted to the study of elastic parameters and, hence, the elastic profile of soils in the field.  Knowledge of a ground’s stiffness profile enables the prediction of ground movement and, thus, the quality of the foundation.  The stiffness parameter obtained in this research corresponds to the measurement of the seismic surface wave phase velocity of materials, which relates to the very small strain shear modulus.  This paper describes a methodology for performing surface wave testing in the laboratory.  In comparison with field tests, a laboratory-scale experiment offers the advantage of allowing the process of data collection to be calibrated, and analytical studies can be carried out as the properties of the material under test are controllable and known a priori.  In addition, a laboratory scale experiment offers insight into the interaction between the seismic surface wave, the soil, the boundary and, hence, the constraints associated with the seismic surface wave technique.  Two simplified models of different sizes were developed using homogeneous remoulded Oxford Clay (from Midlands region of the UK.  The laboratory experimental methodology demonstrated that the seismic surface wave equipment used in the laboratory was directly influenced by the clay properties as well as the size of the test model.  The methodology also showed that the arrangement of the seismic source and the receivers had an impact on the range of reliable frequencies and wavelengths obtained.

  9. Establishment and Preliminary Application of a Rapid Fluorescent Focus Inhibition Test (RFFIT) for Rabies Virus

    Institute of Scientific and Technical Information of China (English)

    Pengcheng Yu; Xinjun Lv; Xinxin Shen; Qing Tang; Guodong Liang

    2013-01-01

    The World Health Organization (WHO) standard assay for determining levels of the rabies virus neutralization antibody (RVNA) is the rapid fluorescent focus inhibition test (RFFIT),which is used to evaluate the immunity effect after vaccination against rabies.For RFFIT,CVS-11 was used as the challenge virus,BSR cells as the adapted cells,and WHO rabies immunoglobulin (WHO STD) as the reference serum in this study.With reference to WHO and Pasteur RFFIT procedures,a micro-RFFIT procedure adapted to our laboratory was produced,and its specificity and reproducibility were tested.We tested levels of RVNA in human serum samples after immunization with different human rabies vaccines (domestic purified Vero cell rabies vaccine (PVRV) and imported purified chick embryo cell vaccine (PCECV)) using different regimens (Zagreb regimen and Essen regimen).We analyzed the levels of RVNA,and compared the immune efficacy of domestic PVRV and imported PCECV using different immunization regimens.The results showed that the immune efficacy of domestic PVRV using the Zagreb regimen was as good as that of the imported PCECV,but virus antibodies were generated more rapidly with the Zagreb regimen than with the Essen regimen.The RFFIT procedure established in our laboratory will enhance the comprehensive detection ability of institutions involved in rabies surveillance in China.

  10. A field assessment of long-term laboratory sediment toxicity tests with the amphipod Hyalella azteca

    Science.gov (United States)

    Ingersoll, Christopher G.; Wang, Ning; Hayward, Jeannie M. R.; Jones, John R.; Jones, Susan B.; Ireland, D. Scott

    2005-01-01

    Response of the amphipod Hyalella azteca exposed to contaminated sediments for 10 to 42 d in laboratory toxicity tests was compared to responses observed in controlled three-month invertebrate colonization exposures conducted in a pond. Sediments evaluated included a sediment spiked with dichlorodiphenyldichloroethane (DDD) or dilutions of a field sediment collected from the Grand Calumet River (GCR) in Indiana (USA) (contaminated with organic compounds and metals). Consistent effects were observed at the highest exposure concentrations (400 ??g DDD/goc [DDD concentrations normalized to grams of organic carbon (goc) in sedimentl or 4% GCR sediment) on survival, length, and reproduction of amphipods in the laboratory and on abundance of invertebrates colonizing sediments in the field. Effect concentrations for DDD observed for 10-d length and 42-d reproduction of amphipods (e.g., chronic value [ChV] of 66 ??g DDD/goc and 25% inhibition concentration [IC25] of 68 ??g DDD/goc for reproduction) were similar to the lowest effect concentrations for DDD measured on invertebrates colonizing sediment the field. Effect concentrations for GCR sediment on 28-d survival and length and 42-d reproduction and length of amphipods (i.e., ChVs of 0.20-0.66% GCR sediment) provided more conservative effect concentrations compared to 10-d survival or length of amphipods in the laboratory or the response of invertebrates colonizing sediment in the field (e.g., ChVs of 2.2% GCR sediment). Results of this study indicate that use of chronic laboratory toxicity tests with H. azteca and benthic colonization studies should be used to provide conservative estimates of impacts on benthic communities exposed to contaminated sediments. Bioaccumulation of DDD by oligochaetes colonizing the DDD-spiked sediment was similar to results of laboratory sediment tests previously conducted with the oligochaete Lumbriculus variegates, confirming that laboratory exposures can be used to estimate

  11. Laboratory Test of a Cylindrical Heat Storage Module with Water and Sodium Acetate Trihydrate

    DEFF Research Database (Denmark)

    Dannemand, Mark; Kong, Weiqiang; Johansen, Jakob Berg;

    2016-01-01

    Cylindrical heat storage modules with internal heat exchangers have been tested in a laboratory. The modules were filled with water and sodium acetate trihydrate with additives. The testing focused on the heat content of the storage material and the heat exchange capacity rate during charge...... of the module. For the tests with the phase change materials, the focus was furthermore on the stability of supercooling and cycling stability. Testing the module with sodium acetate trihydrate and 6.4% extra water showed that phase separation increased and the heat released after solidification of supercooled...... phase change material was reduced over 17 test cycles. The heat released after solidification of the supercooled sodium acetate trihydrate with thickening agent and graphite was stable over the test cycles. Stable supercooling was obtained in 7 out of 17 test cycles with the module with sodium acetate...

  12. Meeting report: discussions and preliminary findings on extracellular RNA measurement methods from laboratories in the NIH Extracellular RNA Communication Consortium

    Science.gov (United States)

    Laurent, Louise C.; Abdel-Mageed, Asim B.; Adelson, P. David; Arango, Jorge; Balaj, Leonora; Breakefield, Xandra; Carlson, Elizabeth; Carter, Bob S.; Majem, Blanca; Chen, Clark C.; Cocucci, Emanuele; Danielson, Kirsty; Courtright, Amanda; Das, Saumya; Elmageed, Zakaria Y. Abd; Enderle, Daniel; Ezrin, Alan; Ferrer, Marc; Freedman, Jane; Galas, David; Gandhi, Roopali; Huentelman, Matthew J.; Van Keuren-Jensen, Kendall; Kalani, Yashar; Kim, Yong; Krichevsky, Anna M.; Lai, Charles; Lal-Nag, Madhu; Laurent, Clara D.; Leonardo, Trevor; Li, Feng; Malenica, Ivana; Mondal, Debasis; Nejad, Parham; Patel, Tushar; Raffai, Robert L.; Rubio, Renee; Skog, Johan; Spetzler, Robert; Sun, Jie; Tanriverdi, Kahraman; Vickers, Kasey; Wang, Liang; Wang, Yaoyu; Wei, Zhiyun; Weiner, Howard L.; Wong, David; Yan, Irene K.; Yeri, Ashish; Gould, Stephen

    2015-01-01

    Extracellular RNAs (exRNAs) have been identified in all tested biofluids and have been associated with a variety of extracellular vesicles, ribonucleoprotein complexes and lipoprotein complexes. Much of the interest in exRNAs lies in the fact that they may serve as signalling molecules between cells, their potential to serve as biomarkers for prediction and diagnosis of disease and the possibility that exRNAs or the extracellular particles that carry them might be used for therapeutic purposes. Among the most significant bottlenecks to progress in this field is the lack of robust and standardized methods for collection and processing of biofluids, separation of different types of exRNA-containing particles and isolation and analysis of exRNAs. The Sample and Assay Standards Working Group of the Extracellular RNA Communication Consortium is a group of laboratories funded by the U.S. National Institutes of Health to develop such methods. In our first joint endeavour, we held a series of conference calls and in-person meetings to survey the methods used among our members, placed them in the context of the current literature and used our findings to identify areas in which the identification of robust methodologies would promote rapid advancements in the exRNA field. PMID:26320937

  13. Meeting report: discussions and preliminary findings on extracellular RNA measurement methods from laboratories in the NIH Extracellular RNA Communication Consortium

    Directory of Open Access Journals (Sweden)

    Louise C. Laurent

    2015-08-01

    Full Text Available Extracellular RNAs (exRNAs have been identified in all tested biofluids and have been associated with a variety of extracellular vesicles, ribonucleoprotein complexes and lipoprotein complexes. Much of the interest in exRNAs lies in the fact that they may serve as signalling molecules between cells, their potential to serve as biomarkers for prediction and diagnosis of disease and the possibility that exRNAs or the extracellular particles that carry them might be used for therapeutic purposes. Among the most significant bottlenecks to progress in this field is the lack of robust and standardized methods for collection and processing of biofluids, separation of different types of exRNA-containing particles and isolation and analysis of exRNAs. The Sample and Assay Standards Working Group of the Extracellular RNA Communication Consortium is a group of laboratories funded by the U.S. National Institutes of Health to develop such methods. In our first joint endeavour, we held a series of conference calls and in-person meetings to survey the methods used among our members, placed them in the context of the current literature and used our findings to identify areas in which the identification of robust methodologies would promote rapid advancements in the exRNA field.

  14. The link between inflammation and coagulation: influence on the interpretation of diagnostic laboratory tests.

    Science.gov (United States)

    Cheng, Teresa; Mathews, Karol; Abrams-Ogg, Anthony; Wood, Darren

    2011-02-01

    This article provides an overview of the complex relationship between inflammation and coagulation and a review of routinely available laboratory and point-of-care tests for the detection of inflammation and coagulopathies. In the management of cases requiring ongoing laboratory and clinical evaluation, examination of these two major pathologic processes may assist with diagnosis and improve outcome. Early identification of a pathologic inflammatory process may allow prevention of its progression to syndromes carrying a poorer prognosis, such as disseminated intravascular coagulation and multiple organ dysfunction syndrome.

  15. Preliminary Safety Analysis Report for the Transuranic Storage Area Retrieval Enclosure at the Idaho National Engineering Laboratory. Revision 8

    Energy Technology Data Exchange (ETDEWEB)

    1993-03-01

    This Transuranic Storage Area Retrieval Enclosure Preliminary Safety Analysis Report was completed as required by DOE Order 5480.23. The purpose of this document is to construct a safety basis that supports the design and permits construction of the facility. The facility has been designed to the requirements of a Radioactive Solid Waste Facility presented in DOE Order 6430.1A.

  16. Inquiry-based laboratory investigations and student performance on standardized tests in biological science

    Science.gov (United States)

    Patke, Usha

    Achievement data from the 3rd International Mathematics and Sciences Study and Program for International Student Assessment in science have indicated that Black students from economically disadvantaged families underachieve at alarming rates in comparison to White and economically advantaged peer groups. The study site was a predominately Black, urban school district experiencing underachievement. The purpose of this correlational study was to examine the relationship between students' use of inquiry-based laboratory investigations and their performance on the Biology End of Course Test, as well as to examine the relationship while partialling out the effects of student gender. Constructivist theory formed the theoretical foundation of the study. Students' perceived levels of experience with inquiry-based laboratory investigations were measured using the Laboratory Program Variable Inventory (LPVI) survey. LPVI scores of 256 students were correlated with test scores and were examined by student gender. The Pearson correlation coefficient revealed a small direct correlation between students' experience in inquiry-based laboratory investigation classes and standardized test scores on the Biology EOCT. A partial correlational analysis indicated that the correlation remained after controlling for gender. This study may prompt a change from teacher-centered to student-centered pedagogy at the local site in order to increase academic achievement for all students. The results of this study may also influence administrators and policy makers to initiate local, state, or nationwide curricular development. A change in curriculum may promote social change as students become more competent, and more able, to succeed in life beyond secondary school.

  17. Reliability of KRAS mutation testing in metastatic colorectal cancer patients across five laboratories

    Directory of Open Access Journals (Sweden)

    Feigelson Heather

    2012-04-01

    Full Text Available Abstract Background Mutations in the KRAS gene are associated with poor response to epidermal growth factor receptor inhibitors used in the treatment of metastatic colorectal cancer. Factors influencing KRAS test results in tumor specimens include: tumor heterogeneity, sample handling, slide preparation, techniques for tumor enrichment, DNA preparation, assay design and sensitivity. We evaluated comparability and consistency of KRAS test results among five laboratories currently being used to determine KRAS mutation status of metastatic colorectal cancer specimens in a large, multi-center observational study. Findings Twenty formalin-fixed paraffin-embedded human colorectal cancer samples from colon resections previously tested for KRAS mutations were selected based on mutation status (6 wild type, 8 codon 12 mutations, and 6 codon 13 mutations. We found good agreement across laboratories despite differences in mutation detection methods. Eighteen of twenty samples (90% were concordant across all five labs. Discordant results are likely not due to laboratory error, but instead to tumor heterogeneity, contamination of the tumor sample with normal tissue, or analytic factors affecting assay sensitivity. Conclusions Our results indicate commercial and academic laboratories provide reliable results for the common KRAS gene mutations at codons 12 and 13 when an adequate percentage of tumor cells is present in the sample.

  18. AGR-1 Irradiated Test Train Preliminary Inspection and Disassembly First Look

    Energy Technology Data Exchange (ETDEWEB)

    Paul Demkowicz; Lance Cole; Scott Ploger; Philip Winston; Binh Pham; Michael Abbott

    2011-01-01

    The AGR-1 irradiation experiment ended on November 6, 2009, after 620 effective full power days in the Advanced Test Reactor, achieving a peak burnup of 19.6% FIMA. The test train was shipped to the Materials and Fuels Complex in March 2010 for post-irradiation examination. The first PIE activities included non-destructive examination of the test train, followed by disassembly of the test train and individual capsules and detailed inspection of the capsule contents, including the fuel compacts and the graphite fuel holders. Dimensional measurements of the compacts, graphite holders, and steel capsules shells were performed using a custom vision measurement system (for outer diameters and lengths) and conventional bore gauges (for inner diameters). Gamma spectrometry of the intact test train gave a preliminary look at the condition of the interior components. No evidence of damage to compacts or graphite components was evident from the isotopic and gross gamma scans. Neutron radiography of the intact Capsule 2 showed a high degree of detail of interior components and confirmed the observation that there was no major damage to the capsule. Disassembly of the capsules was initiated using procedures qualified during out-of-cell mockup testing. Difficulties were encountered during capsule disassembly due to irradiation-induced changes in some of the capsule components’ properties, including embrittled niobium and molybdenum parts that were susceptible to fracture and swelling of the graphite fuel holders that affected their removal from the capsule shells. This required various improvised modifications to the disassembly procedure to avoid damage to the fuel compacts. Ultimately the capsule disassembly was successful and only one compact from Capsule 4 (out of 72 total in the test train) sustained damage during the disassembly process, along with the associated graphite holder. The compacts were generally in very good condition upon removal. Only relatively minor

  19. Whole-blood hemagglutination inhibition test for venereal disease research laboratory (VDRL) antibodies.

    Science.gov (United States)

    Meyer, M P; Baughn, R E

    2000-09-01

    Nontreponemal antibody tests such as the Venereal Disease Research Laboratory (VDRL) test are carried out on serum and widely used as screening tests for syphilis. The aim of the present study was to develop a screening test for syphilis making use of whole blood and VDRL liposomes. Antibody to human red blood cells was conjugated to VDRL liposomes and reacted with a diluted sample of patient whole blood. A total of 951 samples were tested by the new test and the VDRL tube test. All 49 VDRL samples positive by the VDRL test showed inhibition of hemagglutination in the whole-blood test (sensitivity, 100%). Of 902 samples with negative results by the VDRL test, 901 caused hemagglutination when tested with the liposomes (specificity, 99.9%). The hemagglutination inhibition method tests for syphilis in a simple one-step procedure in which whole blood is added to a tube containing liposomes. The new test has potential for point-of-care testing in developing countries.

  20. HFC-134A and HCFC-22 supermarket refrigeration demonstration and laboratory testing. Phase I. Final report

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-04-01

    Aspen Systems and a team of nineteen agencies and industry participants conducted a series of tests to determine the performance of HFC-134a, HCFC-22, and CFC-502 for supermarket application. This effort constitutes the first phase of a larger project aimed at carrying out both laboratory and demonstration tests of the most viable HFC refrigerants and the refrigerants they replace. The results of the Phase I effort are presented in the present report. The second phase of the project has also been completed. It centered on testing all viable HFC replacement refrigerants for CFC-502. These were HFC-507, HFC-404A, and HFC-407A. The latter results are published in the Phase II report for this project. As part of Phase I, a refrigeration rack utilizing a horizontal open drive screw compressor was constructed in our laboratory. This refrigeration rack is a duplicate of one we have installed in a supermarket in Clifton Park, NY.