WorldWideScience

Sample records for pre-production production post-production

  1. Singing emotionally: A study of pre-production, production, and post-production facial expressions

    Directory of Open Access Journals (Sweden)

    Lena Rachel Quinto

    2014-04-01

    Full Text Available Singing involves vocal production accompanied by a dynamic and meaningful use of facial expressions, which may serve as ancillary gestures that complement, disambiguate, or reinforce the acoustic signal. In this investigation, we examined the use of facial movements to communicate emotion, focusing on movements arising in three epochs: before vocalisation (pre-production, during vocalisation (production, and immediately after vocalisation (post-production. The stimuli were recordings of seven vocalists’ facial movements as they sang short (14 syllable melodic phrases with the intention of communicating happiness, sadness, irritation, or no emotion. Facial movements were presented as point-light displays to 16 observers who judged the emotion conveyed. Experiment 1 revealed that the accuracy of emotional judgement varied with singer, emotion and epoch. Accuracy was highest in the production epoch, however, happiness was well communicated in the pre-production epoch. In Experiment 2, observers judged point-light displays of exaggerated movements. The ratings suggested that the extent of facial and head movements is largely perceived as a gauge of emotional arousal. In Experiment 3, observers rated point-light displays of scrambled movements. Configural information was removed in these stimuli but velocity and acceleration were retained. Exaggerated scrambled movements were likely to be associated with happiness or irritation whereas unexaggerated scrambled movements were more likely to be identified as neutral. An analysis of the motions of singers revealed systematic changes in facial movement as a function of the emotional intentions of singers. The findings confirm the central role of facial expressions in vocal emotional communication, and highlight individual differences between singers in the amount and intelligibility of facial movements made before, during, and after vocalization.

  2. Herbal product use by the cancer patients in both the pre and post ...

    African Journals Online (AJOL)

    Conclusion: Analysis of the results indicates that health professionals need to obtain information regarding the use of herbal products by cancer patients during both pre- and post- surgery periods, as well as during chemotherapy. Patients should be provided with information and guidance about the advantages and ...

  3. EMPIRICAL ASSESSMENT OF THE GROWTH RATE OF MAIZE PRODUCTION IN THE PRE - SAP, SAP AND POST - SAP PERIODS IN NIGERIA

    Directory of Open Access Journals (Sweden)

    Oyinbo Oyakhilomen

    2012-05-01

    Full Text Available This study was carried out to provide empirical evidence on the growth rates of maize production in three sub - periods in Nigeria namely pre - Structural Adjustment Programme period, Structural Adjustment Program period and post - Structural Adjustment Programme period. Secondary data on maize production in Nigeria during the Pre - Structural Adjustment Programme period (1970 to 1985, Structural Adjustment period (1986 to 1994 and post - Structural Adjustment Programme period (1995 to 2007 were employed in this study. A growth rate model was used to estimate the growth rates of maize in the three sub - periods. The results of the analysis showed that the instantaneous growth rates of maize production are - 0.1%, 5.7% and 2.4% and the compound rates of growth of maize production are - 0.001%, 0.059% and 0.024% for the pre - Structural Adjustment Programme, Structural Adjustment Programme and post - Structural Adjustment Programme periods respectively. The higher compound growth rate of maize production in the Structural Adjustment Programme period implies that the policy reforms in the period was more effective in ensuring increased growth of maize production over that of other periods in Nigeria. Therefore, despite the myriads of problems associated with the programme in Nigeria, it was beneficial to maize production in Nigeria.

  4. Post-Inflationary Gravitino Production Revisited

    CERN Document Server

    Ellis, John; Nanopoulos, Dimitri V.; Olive, Keith A.; Peloso, Marco

    2016-01-01

    We revisit gravitino production following inflation. As a first step, we review the standard calculation of gravitino production in the thermal plasma formed at the end of post-inflationary reheating when the inflaton has completely decayed. Next we consider gravitino production prior to the completion of reheating, assuming that the inflaton decay products thermalize instantaneously while they are still dilute. We then argue that instantaneous thermalization is in general a good approximation, and also show that the contribution of non-thermal gravitino production via the collisions of inflaton decay products prior to thermalization is relatively small. Our final estimate of the gravitino-to-entropy ratio is approximated well by a standard calculation of gravitino production in the post-inflationary thermal plasma assuming total instantaneous decay and thermalization at a time $t \\simeq 1.2/\\Gamma_\\phi$. Finally, in light of our calculations, we consider potential implications of upper limits on the gravitin...

  5. Post-inflationary gravitino production revisited

    Energy Technology Data Exchange (ETDEWEB)

    Ellis, John [Theoretical Particle Physics and Cosmology Group, Department of Physics, King' s College London, London WC2R 2LS (United Kingdom); Garcia, Marcos A.G.; Olive, Keith A. [William I. Fine Theoretical Physics Institute, School of Physics and Astronomy, University of Minnesota, 116 Church Street SE, Minneapolis, MN 55455 (United States); Nanopoulos, Dimitri V. [George P. and Cynthia W. Mitchell Institute for Fundamental Physics and Astronomy, Texas A and M University, College Station, TX 77843 (United States); Peloso, Marco, E-mail: john.ellis@cern.ch, E-mail: garciagarcia@physics.umn.edu, E-mail: dimitri@physics.tamu.edu, E-mail: olive@physics.umn.edu, E-mail: peloso@physics.umn.edu [School of Physics and Astronomy and Minnesota Institute for Astrophysics, University of Minnesota, 116 Church Street SE, Minneapolis, MN 55455 (United States)

    2016-03-01

    We revisit gravitino production following inflation. As a first step, we review the standard calculation of gravitino production in the thermal plasma formed at the end of post-inflationary reheating when the inflaton has completely decayed. Next we consider gravitino production prior to the completion of reheating, assuming that the inflaton decay products thermalize instantaneously while they are still dilute. We then argue that instantaneous thermalization is in general a good approximation, and also show that the contribution of non-thermal gravitino production via the collisions of inflaton decay products prior to thermalization is relatively small. Our final estimate of the gravitino-to-entropy ratio is approximated well by a standard calculation of gravitino production in the post-inflationary thermal plasma assuming total instantaneous decay and thermalization at a time t ≅ 1.2/Γ{sub φ}. Finally, in light of our calculations, we consider potential implications of upper limits on the gravitino abundance for models of inflation, with particular attention to scenarios for inflaton decays in supersymmetric Starobinsky-like models.

  6. The SPOOKI post production system

    Science.gov (United States)

    Beauchemin, M.; Klasa, M.; Fortier, S.; Fortin, F.; Hardy, G.; Pelletier, L.; Edouard, S.; Archambault, B.; Yazidi, H.

    2010-09-01

    The Canadian Meteorological Centre (CMC) delivers a large number of numerical weather prediction products to the various weather offices and clients throughout Canada and abroad. The current post production system was built according to the needs and ideology of the 1980's and it is becoming obsolete with time. Its cumbersome architecture is difficult to maintain and requires a lot of human and computing resources. The "Weather Elements" section of CMC is aware of the problems associated with its maintenance in the long term and has therefore decided to review in depth the whole approach to the operational post production. The analysis of present and future needs have led to the development of an innovative concept in the operational production field inspired by the "Plug and Play" process. SPOOKI (Système de Production Orienté-Objet contennant une Kyrielle d'Informations - Object oriented production system containing a myriad of information) was created in its present form in 2007. It is based on a modular approach where each plug-in component is specialized, reusable and autonomous. These object oriented programming characteristics greatly simplify the maintenance of the system. Particular attention was also given to create a user-friendly system for novice users. An experimental version of SPOOKI is currently running in development mode and an operational one is planned to be implemented in the coming year. The poster presentation will describe SPOOKI, the future CMC operational post production system. Several examples of usage will be shown.

  7. EOQ model for perishable products with price-dependent demand, pre and post discounted selling price

    Science.gov (United States)

    Santhi, G.; Karthikeyan, K.

    2017-11-01

    In this article we introduce an economic order quantity model for perishable products like vegetables, fruits, milk, flowers, meat, etc.,with price-dependent demand, pre and post discounted selling price. Here we consider the demand is depending on selling price and deterioration rate is constant. Here we developed mathematical model to determine optimal discounton the unit selling price to maximize total profit. Numerical examples are given for illustrated.

  8. Video segmentation for post-production

    Science.gov (United States)

    Wills, Ciaran

    2001-12-01

    Specialist post-production is an industry that has much to gain from the application of content-based video analysis techniques. However the types of material handled in specialist post-production, such as television commercials, pop music videos and special effects are quite different in nature from the typical broadcast material which many video analysis techniques are designed to work with; shots are short and highly dynamic, and the transitions are often novel or ambiguous. We address the problem of scene change detection and develop a new algorithm which tackles some of the common aspects of post-production material that cause difficulties for past algorithms, such as illumination changes and jump cuts. Operating in the compressed domain on Motion JPEG compressed video, our algorithm detects cuts and fades by analyzing each JPEG macroblock in the context of its temporal and spatial neighbors. Analyzing the DCT coefficients directly we can extract the mean color of a block and an approximate detail level. We can also perform an approximated cross-correlation between two blocks. The algorithm is part of a set of tools being developed to work with an automated asset management system designed specifically for use in post-production facilities.

  9. Response diversity, functional redundancy, and post-logging productivity in northern temperate and boreal forests.

    Science.gov (United States)

    Correia, David Laginha Pinto; Raulier, Frédéric; Bouchard, Mathieu; Filotas, Élise

    2018-04-19

    The development of efficient ecosystem resilience indicators was identified as one of the key research priorities in the improvement of existing sustainable forest management frameworks. Two indicators of tree diversity associated with ecosystem functioning have recently received particular attention in the literature: functional redundancy (FR) and response diversity (RD). We examined how these indicators could be used to predict post-logging productivity in forests of Québec, Canada. We analysed the relationships between pre-logging FR and RD, as measured with sample plots, and post-logging productivity, measured as seasonal variation in enhanced vegetation index obtained from MODIS satellite imagery. The effects of the deciduous and coniferous tree components in our pre-disturbance diversity assessments were isolated in order to examine the hypothesis that they have different impacts on post-disturbance productivity. We also examined the role of tree species richness and species identity effects. Our analysis revealed the complementary nature of traditional biodiversity indicators and trait-based approaches in the study of biodiversity-ecosystem-functioning relationships in dynamic ecosystems. We report a significant and positive relationship between pre-disturbance deciduous RD and post-disturbance productivity, as well as an unexpected significant negative effect of coniferous RD on productivity. This negative relationship with post-logging productivity likely results from slower coniferous regeneration speeds and from the relatively short temporal scale examined. Negative black-spruce-mediated identity effects were likely associated with increased stand vulnerability to paludification and invasion by ericaceous shrubs that slow down forest regeneration. Response diversity outperformed functional redundancy as a measure of post-disturbance productivity most likely due to the stand-replacing nature of the disturbance considered. To the best of our knowledge

  10. Pre- and post-hatch trophic egg production in the subsocial burrower bug, Canthophorus niveimarginatus (Heteroptera: Cydnidae)

    Science.gov (United States)

    Filippi, Lisa; Baba, Narumi; Inadomi, Koichi; Yanagi, Takao; Hironaka, Mantaro; Nomakuchi, Shintaro

    2009-02-01

    In recent years, three terrestrial bugs, Adomerus triguttulus and Sehirus cinctus (Cydnidae) and the closely related Parastrachia japonensis (Parastrachiidae), have been the focus of several fascinating studies because of the remarkable, extensive parental care they were found to display. This care includes egg and nymph guarding, production of trophic eggs, unfertilized, low cost eggs that are used as food by newly hatched nymphs, and progressive provisioning of the host seed. In this study, we have investigated yet a third related Asian cydnid, Canthophorus niveimarginatus, with regard to the possible occurrence of some or all of these complex traits in order to assess how widespread these maternal investment patterns are in this group of insects and to better understand the implications of their manifestations from an evolutionary context. Manipulative experiments were carried out in the lab to determine whether females provision nests. Observational and egg removal studies were carried out to determine whether trophic eggs are produced, and, if they are, their possible impact on nymphal success. The findings revealed that C. niveimarginatus does, in fact, progressively provision young, and this species also displays all of the other behaviors associated with extended parental care in subsocial insects. Moreover, unlike the other two related species, which place trophic eggs on the surface of the original egg mass, C. niveimarginatus produces both pre- and post-hatch trophic eggs. Nymphs deprived of access to post-hatch trophic eggs had significantly lower body weight and survival rate than those that fed on them. To our knowledge, this is the first time the production of both pre- and post-hatch trophic eggs has been demonstrated in insects outside the Hymenoptera. In this paper, we qualitatively and quantitatively demonstrate the provisioning behavior and patterns of trophic egg production in C. niveimarginatus. When and how trophic eggs are produced and

  11. Labour productivity and economic growth in the EU in post-crisis period

    OpenAIRE

    Auzina-Emsina, Astra

    2014-01-01

    Labour productivity and economic growth are the major factors to sustain and improve the performance and competitiveness of countries. The paper is devoted to the analysis of recent trends of labour productivity and economic growth in the European Union (EU) countries in post-crisis period in comparison with the trends in pre-crisis and crisis periods. The paper analyses the impact of changes in labour productivity and the effect on the macroeconomic indicators. The research focuses on the Eu...

  12. Insomnia symptoms and their association with workplace productivity: cross-sectional and pre-post intervention analyses from a large multinational manufacturing company.

    Science.gov (United States)

    Espie, Colin A; Pawlecki, Brent; Waterfield, Dickon; Fitton, Kit; Radocchia, Michael; Luik, Annemarie I

    2018-06-01

    Symptoms of insomnia are common and might impact work productivity. We investigated the relationship between insomnia symptoms and workplace productivity in a global manufacturing company. Within an uncontrolled, cross-sectional study, employees from a US-based company were invited to participate in an online evaluation comprising the Sleep Condition Indicator (SCI) measuring symptoms of insomnia (high score indicating better sleep), 2 items of the Work Productivity and Impairment Index (WPAI) measuring 'presenteeism' and 'absenteeism' (high score indicating loss of work productivity) and 1 item of the Perceived Stress Scale (PSS) from January 2015 onwards. Pre-post, within-subject data were collected to preliminary test effects of 'sleep tips' and digital cognitive behavioral therapy (dCBT). In 2798 employees [72% male; mean age 46.3(SD11.8) yrs] sleep was poorest in plant staff [SCI = 3.70(2.73)], then retail staff [4.34(3.02)], then office staff [4.95(2.83): overall F(2,2786) = 43.7, P work-related productivity, with stress only contributing a further 9%. A regression model for 'absenteeism' was statistically significant but of limited predictive value (R 2 = 3.4%). In a sample of 214 employees with pre- and post-intervention data, the SCI of those exposed to sleep tips significantly increased from 5.36(3.28) to 6.01(3.22), [t(123) = -3.02, P = .003] and from 3.08(2.24) to 6.03(2.97) for those who accessed dCBT [t(89) = -8.40, P work productivity. Additionally, targeted insomnia interventions may offer potential to improve sleep and work productivity. Copyright © 2018 National Sleep Foundation. Published by Elsevier Inc. All rights reserved.

  13. [Subjectivity, ethics and productivity in post-productive health restructuring].

    Science.gov (United States)

    Gomes, Doris; Ramos, Flávia Regina Souza

    2015-08-01

    The scope of this paper is to analyze the ethical problems generated by the modern stressor pattern of post-transformation productivity in productive restructuring in the health area. It is a qualitative study of the descriptive and exploratory type in which 30 professionals (nurses, doctors and dental surgeons) from a metropolitan region in the South of Brazil were interviewed, all of whom had prior experience in the public and private sectors. The results were analyzed through Discursive Textual Analysis. Capitalization is revealed as a major ethical problem in the series of new issues derived from the productivity-profitability imperative in health, due to the acritical incorporation of ethics that is restricted to the company's interests or to corporate-individual interests. The ethical problem of low professional commitment to the needs of the patient and of the social collective indicates the need to build a new engaged solidarity in order to increase the quality of public healthcare. Productivity targeted at individual and social needs/interests in the area of health requires a new self-managing and collective engagement of the subjects, supported by an institutional and ethical-political effort of group action, cooperation and solidarity.

  14. Pre- and Peri-/Post-Compaction Follistatin Treatment Increases In Vitro Production of Cattle Embryos.

    Directory of Open Access Journals (Sweden)

    Guo Zhenhua

    Full Text Available Our previous studies demonstrated that maternal (oocyte derived follistatin (FST expression is positively associated with bovine oocyte competence and exogenous follistatin treatment during the pre-compaction period of development (d 1-3 post insemination is stimulatory to bovine early embryogenesis in vitro [blastocyst rates and cell numbers/allocation to trophectoderm (TE]. In the present study, bovine embryos were treated with exogenous follistatin during d 1-3, d 4-7 and d 1-7 post insemination to test the hypothesis that embryotropic effects of exogenous follistatin are specific to the pre-compaction period (d 1-3 of early embryogenesis. Follistatin treatment during d 4-7 (peri-/post-compaction period of embryo culture increased proportion of embryos reaching blastocyst and expanded blastocyst stage and total cell numbers compared to controls, but blastocyst rates and total cell numbers were lower than observed following d 1-3 (pre-compaction follistatin treatment. Follistatin supplementation during d 1-7 of embryo culture increased development to blastocyst and expanded blastocyst stages and blastocyst total cell numbers compared to d 1-3 and d 4-7 follistatin treatment and untreated controls. A similar increase in blastocyst CDX2 mRNA and protein (TE cell marker was observed in response to d 1-3, d 4-7 and d 1-7 follistatin treatment. However, an elevation in blastocyst BMP4 protein (TE cell regulator was observed in response to d 1-3 and d 1-7, but not d 4-7 (peri-/post-compaction follistatin treatment. In summary, our study revealed the potential utility of follistatin treatment for increasing the success rate of in vitro embryo production in cattle. Such results also expand our understanding of the embryotropic actions of follistatin and demonstrate that follistatin actions on blastocyst development and cell allocation to the TE layer are not specific to the pre-compaction period.

  15. Product samples stimulate choice of unfamiliar healthful food products.

    Science.gov (United States)

    Schickenberg, B; van Assema, P; Brug, J; de Vries, N K

    2011-08-01

    The purpose of this study was to assess whether the availability of a product sample of an unfamiliar low-fat or fruit and vegetable products stimulates choice for this product among food neophobic young adults. The study had a 2 (experimental vs. control group) by 4 (low-fat bread spread, low-fat cheese, fruit juice, fruit and vegetable juice) between subjects design with a pre-and post-experiment questionnaire. The study was conducted in restaurant rooms of several educational institutions in the Netherlands among a convenience sample of 197 food neophobic young adults aged 17-25 years. A small bite or sip-sized sample of the target product was provided as an intervention. The effect measure was choice of either an unfamiliar healthful food product or a traditional food product. Offering a sample of an unfamiliar healthful food product resulted in 51% of the participants in the experimental group choosing this product vs. 36.4% in the control group. Providing food product samples seems to be a promising strategy in healthy diet promotion programs for food neophobic young adults to increase first-time trial of unfamiliar low-fat and fruit and vegetable products. Copyright © 2011 Elsevier Ltd. All rights reserved.

  16. Improving Post-Hurricane Katrina Forest Management with MODIS Time Series Products

    Science.gov (United States)

    Lewis, Mark David; Spruce, Joseph; Evans, David; Anderson, Daniel

    2012-01-01

    Hurricane damage to forests can be severe, causing millions of dollars of timber damage and loss. To help mitigate loss, state agencies require information on location, intensity, and extent of damaged forests. NASA's MODerate Resolution Imaging Spectroradiometer (MODIS) Normalized Difference Vegetation Index (NDVI) time series data products offers a potential means for state agencies to monitor hurricane-induced forest damage and recovery across a broad region. In response, a project was conducted to produce and assess 250 meter forest disturbance and recovery maps for areas in southern Mississippi impacted by Hurricane Katrina. The products and capabilities from the project were compiled to aid work of the Mississippi Institute for Forest Inventory (MIFI). A series of NDVI change detection products were computed to assess hurricane induced damage and recovery. Hurricane-induced forest damage maps were derived by computing percent change between MODIS MOD13 16-day composited NDVI pre-hurricane "baseline" products (2003 and 2004) and post-hurricane NDVI products (2005). Recovery products were then computed in which post storm 2006, 2007, 2008 and 2009 NDVI data was each singularly compared to the historical baseline NDVI. All percent NDVI change considered the 16-day composite period of August 29 to September 13 for each year in the study. This provided percent change in the maximum NDVI for the 2 week period just after the hurricane event and for each subsequent anniversary through 2009, resulting in forest disturbance products for 2005 and recovery products for the following 4 years. These disturbance and recovery products were produced for the Mississippi Institute for Forest Inventory's (MIFI) Southeast Inventory District and also for the entire hurricane impact zone. MIFI forest inventory products were used as ground truth information for the project. Each NDVI percent change product was classified into 6 categories of forest disturbance intensity. Stand age

  17. Pre-produsage and the remediation of virtual products

    Science.gov (United States)

    Skågeby, Jörgen

    2011-04-01

    This paper introduces and explores cycles of pre-produsage and produsage. It reports on the results from an online ethnographical study of the Apple iPad conducted before the public release of the material product. Consequently, most users had not physically interacted with the device in question. Nevertheless, the release of the technical specifications and marketing material generated a massive amount of produsage-related online discussion. As such this paper explores the concept of pre-produsage. Pre-produsage is a form of predicted or expected use, relating to products or services that are only accessible to users as a form of representation (e.g. technical specification, virtual prototype, and design sketch), but with an added element of user-generated design suggestions, conflict coordination, and software development. Remediation-the process by which new digital media technologies reuses qualities of previous technologies and enters an existing media ecology-is a prevalent theme in pre-produsage and involves a tension between features that support protracted use and features that provide total innovation. The paper argues that an analysis of pre-produsage can provide insights that relate to both anticipated and actual user experience (UX). More specifically, pre-produsage analysis can trace the underlying reasons for a certain problem, intention, or concern and connect it to a specific set of features and potential solutions. Finally, the paper shows how proprietary products become subject to produsage, resulting in artifacts negotiated by cycles of produsage.

  18. 30 CFR 14.10 - Post-approval product audit.

    Science.gov (United States)

    2010-07-01

    ..., AND APPROVAL OF MINING PRODUCTS REQUIREMENTS FOR THE APPROVAL OF FLAME-RESISTANT CONVEYOR BELTS General Provisions § 14.10 Post-approval product audit. (a) Approved conveyor belts will be subject to... based. MSHA will select an approved conveyor belt to be audited; the selected belt will be...

  19. POST-LAUNCHING MONITORING ACTIVITIES FOR NEW TRANSACTIONAL BANKING PRODUCTS ADDRESSED TO SMES (CONSIDERATIONS

    Directory of Open Access Journals (Sweden)

    Giuca Simona-Mihaela

    2014-07-01

    Full Text Available The current paper has the aim to provide guidelines for post-launching monitoring activities and steps related to new transactional banking products addressed to SMEs. While the pre-launching activities have the purpose of accurately defining the objectives, assumptions and estimations, the purpose of the post-launching plan is to identify: if the final objectives of a product launching have been met, on one hand, to analyze results in the sense of identifying an efficient action plan in order to overcome the lack of results (if case, but most important, to identify opportunities for optimizing the products and for communicating properly the value proposition. This paper also presents schemes for monitoring the results from a business case and for motivating the sales force, as an essential step in increasing the sales. Therefore, alternatives of incentive campaigns are presented, as sustainable campaigns with to purpose to achieve an expected success rate. As an additional support guideline for the sales force, some scenarios and post-sales actions are presented, together with an example of portfolio analysis considering potential per client. Considering the methods and details presented in the current paper, one can identify the importance and find out how to monitor the results after launching a new transactional product addressed to SMEs, can understand and design an incentive scheme and also define actions to be taken in order to increase revenues from a newly launched transactional product.

  20. Measurable Changes in Pre-Post Test Scores in Iraqi 4-H Leader’s Knowledge of Animal Science Production Principles

    Directory of Open Access Journals (Sweden)

    Justen O. Smith

    2015-06-01

    Full Text Available The 4-H volunteer program is a new concept to the people of Iraq, for decades the country has been closed to western ideas. Iraqi culture and the Arabic customs have not embraced the volunteer concept and even more the concept of scientific animal production technologies designed to increase profitability for producers. In 2011 the USAID-Inma Agribusiness program teamed with the Iraq 4-H program to create youth and community entrepreneurship opportunities for widowed families. Iraq 4-H provided the youth members and adult volunteers and Inma provided the financial capital (livestock and the animal science training program for the volunteers. The purpose of this study was to measure the knowledge level gained through intensive animal science training for Iraqi 4-H volunteers. Researchers designed and implemented a pre and post test to measure the knowledge of fifteen volunteers who participated in the three day course. The pretest exposed a general lack of animal science knowledge of all volunteers; over 80% of the participants incorrectly answered the questions. However, the post-test indicated positive change in the participants understanding of animal science production principles.

  1. Infrared pre-drying and dry-dehulling of walnuts for improved processing efficiency and product quality

    Science.gov (United States)

    The walnut industry is faced with an urgent need to improve post-harvest processing efficiency, particularly drying and dehulling operations. This research investigated the feasibility of dry-dehulling and infrared (IR) pre-drying of walnuts for improved processing efficiency and dried product quali...

  2. Interchangeability of biosimilar and biological reference product: updated regulatory positions and pre- and post-marketing evidence.

    Science.gov (United States)

    Trifirò, Gianluca; Marcianò, Ilaria; Ingrasciotta, Ylenia

    2018-03-01

    Since 2006, biosimilars have been available in several countries worldwide, thus allowing for potential savings in pharmaceutical expenditure. However, there have been numerous debates about the interchangeability of biosimilars and reference products based on concerns of immunogenicity by switching between biological products, which may cause lack of effect and toxicity. Areas covered: The authors provide the reader with an overview of the different positions of regulatory authorities on the interchangeability and automatic substitution of biosimilars and reference products. Presently, the FDA allows automatic substitution without prescriber intervention if the biosimilar is interchangeable with reference products, while the European Medicines Agency delegate to each single EU member state. Expert opinion: Different approaches in defining interchangeability and automatic substitution call for harmonization to increase confidence of healthcare professionals and patients about the clinical impact of switching. Networks of electronic healthcare records and administrative databases, potentially linkable to clinical charts and registries may rapidly assess frequency and benefit-risk profile of different switching patterns in routine care at different levels, thus integrating and strengthening pre-marketing evidence.

  3. Life cycle and production of Baetis rhodani in a regulated river in Western Norway: comparison of pre- and post-regulation conditions

    International Nuclear Information System (INIS)

    Raddum, G.G.; Fjellheim, A.

    1993-01-01

    The benthic invertebrate fauna of the lowland part of the Aurland River was investigated in 1966-7 over a full year cycle. The watershed was built out for hydropower production during 1979-83. In this study the life cycle and production of Baetis rhodani from pre-regulated conditions (1966-7) was compared with two types of post-regulation streams(1988-9). Before regulation the water flow was high during May-June and in autumn, combined with heavy rainfall. The lowest flow was in winter and early spring. The pre-regulated temperature was low in winter, increasing from April to a maximum in August (10-14 o C). After regulation one part of the river received reduced flow and increased summer temperatures (upper part) and one received hypolimnion release and reduced summer temperatures (lower part). In the upper part the density of B.rhodani increased between 10 and 20 times. The reason for this seems to be increased temperature, reduced accidental drift of larvae and increased amount of stored organic material on the bottom. In the lower part the density increase was two to five times and the production two times higher after regulation. The lower increase in production than density was due to a much higher proportion of small larvae. B.rhodani had mainly an univoltine life cycle before regulation, but a small part of the population was bivoltine. After regulation the species was univoltine in the lower part. In the upper part the life cycle was about one month faster, but no clear indication of bivoltinism was seen. The absence of the second generation is due to low temperatures and probably a lack of signals connected with temperature. (Author)

  4. A Genealogy of (post-Soviet Dependency: Disabling Productivity

    Directory of Open Access Journals (Sweden)

    Cassandra Hartblay

    2014-02-01

    Full Text Available Nancy Fraser and Linda Gordon's 1994 article “A Genealogy of Dependency: Tracing a Keyword of the US Welfare State” explored the historical emergence of "dependency" as a moral category of post-industrial American state. In this article, I engage their framework to explore the genealogy of dependency in America's post-industrial sister, the post-Soviet Russian Federation. I also add disability as a core element of 'dependency' that was largely absent from Fraser and Gordon's original analysis. Considering cross-cultural translation, I ask how Russian deployments of three words that all relate to a concept of interdependence align with and depart from American notions of dependency, and trace historical configurations of the Soviet welfare state vis-a-vis disability. To do so, I draw on historical and cultural texts, linguistic comparisons, secondary sources, and ethnographic research. Given this analysis, I argue that rather than a Cold War interpretation of the Soviet Union and the US as oppositional superpowers in the 20th century, a liberatory disability studies framework suggests that in the postindustrial era the Soviet Union and the United States emerged as dual regimes of productivity. I suggest that reframing postsocialism as a global condition helps us to shift considerations of disability justice from a critique of capitalism to a critique of productivity.    Keywords: dependency, disability, citizenship, russia, productivity

  5. JOINT DETERMINATION OF PRICE, WAR RANTY LENGTH AND PRODUCTION QUANTITY FOR NEW PRODUCTS UNDER FREE RENEWAL WARRANTY POLICY

    Directory of Open Access Journals (Sweden)

    K. Jeyakumar

    2010-03-01

    Full Text Available An optimal business strategy which integrates the decisions, such as pricing, production quantity, and custom er service, in or der to maximize profit is vital for any manufacturing industry. Post sale factors like warranty, spare parts availability, maintenance, service and cost play an important role in the sale of a product. As better warranty signals higher product quality which provides greater assurance to customers, warranty is an important factor in marketing new products. In this paper, a decision model with the price, warranty length and production quantity of a product as decision variables to maximize profit based on the pre-determined product life cycle is presented. The study considers free renewal warranty policy for producers in the static sales market. The expected number of renewals based on the warranty length is derived for lognormally distributed products. The effect of model parameters on the profit is studied.

  6. A spatial application of a vegetation productivity equation for neo-soil reconstruction

    International Nuclear Information System (INIS)

    Burley, J.B.

    1999-01-01

    Reclamation specialists are interested in the application of recently developed soil productivity equations for post-mining reclamation planning and design. This paper presents the application of one recently developed soil productivity equation to a surface coal mine site in Mercer County, North Dakota. Geographic information systems (GIS) technology (Map*Factory 1.1) was combined with a soil productivity equation developed by the author to generate a GIS script to calculate a site's pre-mining productivity per 10 meter grid cell and then summed to calculate the grand and the expected average soil productivity for the site, resulting in a pre-mining baseline numerical spatial scores. Several post-mining alternatives were evaluated to study various soil management strategies to restore post-mining soil productivity, including: an abandoned mine landscape treatment, a reconstructed topsoil treatment with graded gentile slopes, and a reconstructed topsoil treatment with soil improvements. The results indicated that the abandoned mine scenario was significantly different than the other three treatments (ple0.05), with the reconstructed topsoil treatment with soil amendments generating the greatest estimated productivity

  7. Role of the pre- and post-natal environment in developmental programming of health and productivity.

    Science.gov (United States)

    Reynolds, Lawrence P; Caton, Joel S

    2012-05-06

    The concept that developmental insults (for example, poor pre- or postnatal nutrition) can have long-term consequences on health and well-being of the offspring has been termed developmental programming. In livestock, developmental programming affects production traits, including growth, body composition, and reproduction. Although low birth weight was used as a proxy for compromised fetal development in the initial epidemiological studies, based on controlled studies using livestock and other animal models in the last two decades we now know that developmental programming can occur independently of any effects on birth weight. Studies in humans, rodents, and livestock also have confirmed the critical role of the placenta in developmental programming. In addition, the central role of epigenetic regulation in developmental programming has been confirmed. Lastly, relatively simple therapeutic/management strategies designed to 'rescue' placental development and function are being developed to minimize the effects of developmental programming on health and productivity of humans, livestock, and other mammals. Copyright © 2011 Elsevier Ireland Ltd. All rights reserved.

  8. Adhesion improvement of lignocellulosic products by enzymatic pre-treatment.

    Science.gov (United States)

    Widsten, Petri; Kandelbauer, Andreas

    2008-01-01

    Enzymatic bonding methods, based on laccase or peroxidase enzymes, for lignocellulosic products such as medium-density fiberboard and particleboard are discussed with reference to the increasing costs of presently used petroleum-based adhesives and the health concerns associated with formaldehyde emissions from current composite products. One approach is to improve the self-bonding properties of the particles by oxidation of their surface lignin before they are fabricated into boards. Another method involves using enzymatically pre-treated lignins as adhesives for boards and laminates. The application of this technology to achieve wet strength characteristics in paper is also reviewed.

  9. Complementary or alternative? The use of homeopathic products and antibiotics amongst pre-school children

    Directory of Open Access Journals (Sweden)

    Bishop Jackie

    2008-01-01

    Full Text Available Abstract Background Any intervention to reduce the inappropriate use of antibiotics for infections in children has the potential to reduce the selective pressure on antimicrobial resistance and minimise the medicalisation of self-limiting illness. Little is known about whether homeopathic products might be used by some families as an alternative to antibiotics or the characteristics of such families. We used the Avon Longitudinal Study of Parents and Children (ALSPAC observational dataset to explore the hypothesis that the use of homeopathic products is associated with reduced antibiotic use in pre-school children and to identify characteristics of the families of pre-school children given homeopathic products. Methods Questionnaires data were completed by the parents of 9723 children while aged between 3–4.5 years in Bristol UK. Univariable and multivariable analyses were used to explore the relationships between antibiotic and homeopathic product use. Results Six percent of children had received one or more homeopathic products and 62% one or more antibiotics between the ages of 3 and 4.5 years. After adjustment for factors associated with antibiotic use, there was no association between homeopathic product and antibiotic use (adjusted OR = 1.02, 95% CI 0.84, 1.24. Factors independently associated with child homeopathic product use were: higher maternal education, maternal use of homeopathic products, maternal lack of confidence in doctors, mothers reporting that they were less likely to see doctor when the child was ill, children being given vitamins, watching less television and suffering from wheeze and food allergies. Conclusion In this observational study, the use of homeopathic products was not associated with decreased antibiotic consumption, suggesting the use of homeopathic product complements rather than competes with the use of antibiotics in pre-school children. The characteristics of mothers giving homeopathic products to their

  10. Biomarker Analysis of Stored Blood Products: Emphasis on Pre-Analytical Issues

    Science.gov (United States)

    Delobel, Julien; Rubin, Olivier; Prudent, Michel; Crettaz, David; Tissot, Jean-Daniel; Lion, Niels

    2010-01-01

    Millions of blood products are transfused every year; many lives are thus directly concerned by transfusion. The three main labile blood products used in transfusion are erythrocyte concentrates, platelet concentrates and fresh frozen plasma. Each of these products has to be stored according to its particular components. However, during storage, modifications or degradation of those components may occur, and are known as storage lesions. Thus, biomarker discovery of in vivo blood aging as well as in vitro labile blood products storage lesions is of high interest for the transfusion medicine community. Pre-analytical issues are of major importance in analyzing the various blood products during storage conditions as well as according to various protocols that are currently used in blood banks for their preparations. This paper will review key elements that have to be taken into account in the context of proteomic-based biomarker discovery applied to blood banking. PMID:21151459

  11. Production Of Hollow Toy Product From Radiation Pre vulcanized Natural Rubber Latex (RVNRL) By Using Casting And Moulding Technique

    International Nuclear Information System (INIS)

    Mohd Noorwadi Mat Lazim; Sofian Ibrahim; Muhammad Saiful Omar

    2013-01-01

    Hollow toy products are very synonym to the child from the age of months since it able to stimulating each of their sense such as sight, hearing, taste, touch and smell. Most of hollow toy products are made from natural rubber latex by using moulding and casting technique. The moulding and casting technique is a manufacturing process by pored liquid latex into a mould, which contain cavity of the desired shape. The mould made from plaster of Paris able to absorbs water from latex meanwhile the presence of calcium ions from plaster of Paris will tend to diffuse into latex thus promote formation of deposit on surface of cavity mould. To improve the quality and safety of hollow toy product made from latex, Radiation Pre vulcanized Natural Rubber Latex (RVNRL) has been identified to be used because it can fulfill the standard requirement for latex and also due to its special abilities such as lower modulus (soft latex products), nitrosamines free, low in nitrosatables, free from chemical accelerators induced allergies and better biodegradability. This paper identify the problem appears from the process of making hollow toy products from RVNRL by using moulding and casting technique. (author)

  12. Utilisation of Products of the Thermal Reclamation of Post Reclamation Dusts in the Production Technology of Ceramic Building Materials

    Directory of Open Access Journals (Sweden)

    Holtzer M.

    2015-12-01

    Full Text Available The problem related to the management of post reclamation dusts generated in the reclamation process of waste moulding sands with organic binders is presented in the hereby paper. Waste materials generated in this process are products hazardous for the environment and should be utilised. The prototype stand for the utilisation of this dangerous material in its co-burning with coal was developed and patented in AGH in Krakow. The stand was installed in one of the domestic casting houses. As the utilisation result the transformed waste product is obtained and its management in the production of ceramic materials constitutes the subject of the presented publication.

  13. 77 FR 48550 - Technicolor Creative Services, Post Production Feature Mastering Division Including On-Site...

    Science.gov (United States)

    2012-08-14

    ... Services, Post Production Feature Mastering Division Including On-Site Leased Workers From Ajilon... Services, Post Production Feature Mastering Division, Hollywood, California (subject firm). The worker... the workers meet the eligibility requirements of the Trade Act of 1974. Conclusion After careful...

  14. Preliminary Screening of Potential Control Products against Drosophila suzukii

    Directory of Open Access Journals (Sweden)

    Andrew G. S. Cuthbertson

    2014-06-01

    Full Text Available The first recording of Drosophila suzukii in the UK occurred in the south of England during August 2012. Since then sticky traps have continued to record the presence of individuals. Several products (both chemical and biological were investigated for their efficacy against different life-stages of the pest. Both direct and indirect exposure to control products was assessed. Spinosad, chlorantraniliprole and the experimental product, TA2674, showed excellent potential as control agents when used as either a pre- or post-dipping treatment for blueberries with mortalities of 100%, 93% and 98% mortality, respectively, being achieved following pre-treatment. Direct spray application of all products tested had limited impact upon adult flies. Highest mortality (68% was achieved following direct application of TA2674. Entomopathogenic agents (nematodes and fungi tested appeared to reduce fly population development (ranges of 34–44% mortality obtained but would seem unable to eradicate outbreaks. The potential of the tested products to control D. suzukii is discussed.

  15. Vinegar production from post-distillation slurry deriving from rice shochu production with the addition of caproic acid-producing bacteria consortium and lactic acid bacterium.

    Science.gov (United States)

    Yuan, Hua-Wei; Tan, Li; Chen, Hao; Sun, Zhao-Yong; Tang, Yue-Qin; Kida, Kenji

    2017-12-01

    To establish a zero emission process, the post-distillation slurry of a new type of rice shochu (NTRS) was used for the production of health promoting vinegar. Since the NTRS post-distillation slurry contained caproic acid and lactic acid, the effect of these two organic acids on acetic acid fermentation was first evaluated. Based on these results, Acetobacter aceti CICC 21684 was selected as a suitable strain for subsequent production of vinegar. At the laboratory scale, acetic acid fermentation of the NTRS post-distillation slurry in batch mode resulted in an acetic acid concentration of 41.9 g/L, with an initial ethanol concentration of 40 g/L, and the acetic acid concentration was improved to 44.5 g/L in fed-batch mode. Compared to the NTRS post-distillation slurry, the vinegar product had higher concentrations of free amino acids and inhibition of angiotensin I converting enzyme activity. By controlling the volumetric oxygen transfer coefficient to be similar to that of the laboratory scale production, 45 g/L of acetic acid was obtained at the pilot scale, using a 75-L fermentor with a working volume of 40 L, indicating that vinegar production can be successfully scaled up. Copyright © 2017 The Society for Biotechnology, Japan. Published by Elsevier B.V. All rights reserved.

  16. 9 CFR 430.4 - Control of Listeria monocytogenes in post-lethality exposed ready-to-eat products.

    Science.gov (United States)

    2010-01-01

    ... post-lethality exposed ready-to-eat products. 430.4 Section 430.4 Animals and Animal Products FOOD... Control of Listeria monocytogenes in post-lethality exposed ready-to-eat products. (a) Listeria... comes into direct contact with a food contact surface which is contaminated with L. monocytogenes. (b...

  17. Tumor markers: applications and recommendations. New IZOTOPE products

    International Nuclear Information System (INIS)

    Gyenes, Ana Rosa

    2016-01-01

    At work aspects are discussed: Tumor markers; New products IZOTOP; Measuring principle of IRMA kits for tumor markers; Guidelines and Recommendations for the use of tumor markers. pre-analytical, post-analytical and Quality control recommendations are given

  18. The acceptance of gamma irradiated pre-cooked processed chicken meat products

    International Nuclear Information System (INIS)

    Seri Chempaka Mohd Yusof; Muhamad Lebai Juri; Foziah Ali; Salahbiah Abdul Majida; Mariani Deraman; Ros Anita Ahmad Ramli; Rohaizah Ahmad; Zainab Harun; Abdul Salam Babji

    2009-01-01

    A study was carried out to determine suitable dose, microbiological counts including pathogens and sensory evaluation of pre-cooked chicken meat products in assessing the acceptability of irradiated pre-cooked chicken meat products. Packed pre-cooked chicken sausages and burger samples (sealed individually in plastic-polyethylene pouches) were irradiated at the following doses: 2.5 kGy, 3.5 kGy and 5.5 kGy using 60 Co gamma irradiation at MINTec-Sinagama. Acceptability of the sausages was determined through sensory evaluation by 30 members of untrained panelists comprising staff of Malaysian Nuclear Agency. A 5-points hedonic rating scale was used. The attributes evaluated were taste, texture, chewiness, juiciness, aroma, colour, shape and overall acceptance. Samples irradiated with dose of 5.5 kGy were the most acceptable, followed by samples irradiated at 3.5 kGy and 10 kGy. Irradiation at doses up to 3.5 kGy render undetectable microorganisms/fungi and pathogens (faecal coliforms, Salmonella sp., Escherichia coli and Staphylococcus aureus) in pre-cooked chicken sausages, and doses up to 5.5 kGy for pre-cooked chicken burgers

  19. Enhanced methane production from pig slurry with pulsed electric field pre-treatment.

    Science.gov (United States)

    Safavi, Seyedeh Masoumeh; Unnthorsson, Runar

    2018-02-01

    Intensive amount of manure produced in pig breeding sectors represents negative impact on the environment and requires optimal management. Anaerobic digestion as a well-known manure management process was optimized in this experimental study by pulsed electric field (PEF) pre-treatment. The effect of PEF on methane production was investigated at three different intensities (15, 30 and 50 kWh/m 3 ). The results indicate that the methane production and chemical oxygen demand (COD) removal was improved by continuous escalation of applied intensity, up to 50 kWh/m 3 . In comparison with untreated slurry, methane production and COD removal were increased up to 58% and 44%, respectively.

  20. EDUCATION AS BASIS OF FORMATION OF «NEW PRODUCTIVE FORCES» IN POST-INDUSTRIAL SOCIETY

    Directory of Open Access Journals (Sweden)

    Mikhail Grechko

    2016-12-01

    Full Text Available Search of trajectories of transformation of domestic economy and society, in aspect of transition to a post-industrial stage of development, is actual and significant for today. In the author presented to article it is reasoned that synchronous formation of the «new productive forces» adequate to the formed relations of production in post-industrial society has to become the main imperative of development of domestic economy. Taking into account conceptual results of the political economic, evolutionary and institutional economic theory, the author put forward and proved situation that the new productive forces serving subsequently as basis for formation of relations of production adequate to them in borders of a post-industrial stage of development, have to be formed in sectors of generation of knowledge, thus the special part is assigned to educational sector. In the conclusion the main conclusions on the conducted research are systematized.

  1. Optimization of instant dalia dessert pre-mix production by using response surface methodology.

    Science.gov (United States)

    Jha, Alok; Shalini, B N; Patel, Ashok Ambalal; Singh, Mithilesh; Rasane, Prasad

    2015-02-01

    Dalia, a wheat-based, particulate containing dairy dessert is popularly consumed as a breakfast food and is also considered as a health food. Though popular throughout Northern parts of the country, its limited shelf-life even under refrigeration imposes severe restrictions on its organized manufacture and marketing. In order to promote dalia dessert as a marketable product, in the present study, a process was developed for manufacture of instant dalia pre-mix, as a dry product with long shelf-life, which could be attractively packaged and easily reconstituted for consumption. During the investigation, the effect of different levels of milk solids and wheat solids was studied on dalia pre-mix quality by employing a central composite rotatable design (CCRD). The suggested formulation had 17.82 % milk solids and 2.87 % wheat solids. This formulation was found to be most appropriate for manufacture of instant dalia pre-mix with predicted sensory scores (Max. 100) of 85.35, 41.98 and 67.27 for mouthfeel, consistency and flavor, respectively; the viscosity of the product was 941.0 cp.

  2. Yeast diversity and dynamics in the production processes of Norwegian dry-cured meat products.

    Science.gov (United States)

    Asefa, Dereje T; Møretrø, Trond; Gjerde, Ragnhild O; Langsrud, Solveig; Kure, Cathrine F; Sidhu, Maan S; Nesbakken, Truls; Skaar, Ida

    2009-07-31

    This study investigate the diversity and dynamics of yeasts in the production processes of one unsmoked and two smoked dry-cured meat products of a Norwegian dry-cured meat production facility. A longitudinal observational study was performed to collect 642 samples from the meat, production materials, room installations and indoor and outdoor air of the production facility. Nutrient rich agar media were used to isolate the yeasts. Morphologically different isolates were re-cultivated in their pure culture forms. Both classical and molecular methods were employed for species identification. Totally, 401 yeast isolates belonging to 10 species of the following six genera were identified: Debaryomyces, Candida, Rhodotorula, Rhodosporidium, Cryptococcus and Sporidiobolus. Debaryomyces hansenii and Candida zeylanoides were dominant and contributed by 63.0% and 26.4% respectively to the total isolates recovered from both smoked and unsmoked products. The yeast diversity was higher at the pre-salting production processes with C. zeylanoides being the dominant. Later at the post-salting stages, D. hansenii occurred frequently. Laboratory studies showed that D. hansenii was more tolerant to sodium chloride and nitrite than C. zeylanoides. Smoking seems to have a killing or a temporary growth inhibiting effect on yeasts that extend to the start of the drying process. Yeasts were isolated only from 31.1% of the environmental samples. They belonged to six different species of which five of them were isolated from the meat samples too. Debaryomyces hansenii and Rhodotorula glutinis were dominant with a 62.6% and 22.0% contribution respectively. As none of the air samples contained D. hansenii, the production materials and room installations used in the production processes were believed to be the sources of contamination. The dominance of D. hansenii late in the production process replacing C. zeylanoides should be considered as a positive change both for the quality and safety

  3. 77 FR 26795 - Product List Changes

    Science.gov (United States)

    2012-05-07

    ... the United States Postal Service to Transfer Parcel Post to the Competitive Product List, April 26... Service request to remove Parcel Post from the market dominant product list and to add a nearly identical ``Parcel Post'' to the competitive product list. Alaska Bypass Service would remain on the market dominant...

  4. Irradiation of pre-packaged sliced cooked meat products with low and normal sodium content

    International Nuclear Information System (INIS)

    Stekelenburg, F.K.

    1990-01-01

    Irradiation experiments were carried out with pre-packaged sliced cooked meat products with different initial counts of Enterobacteriaceae and mesophilic aerobic bacteria. In low-sodium meat products Enterobacteriaceae could effectively be inactivated in refrigerated or frozen products by irradiation with a dose of 1 or 2 kGy respectively, provided the number of these bacteria was below 10(3) to 10(4) per g. The low-sodium meat products involved endured above treatment without being seriously affected as to sensory qualities. Shelf-life of salted cooked meat products could be prolonged by irradiating the frozen product. Irradiation with a dose of 2 kGy enabled uncooled storage of the product for a restricted period (5-7 days). Best results were obtained for meat products with a salt content in the brine phase of greater than 4.0% (w/w) and having a good hygienic quality, i.e. an initial bacterial count below 10(4)/g. Packaging in a gas atmosphere (CO2) slightly enhanced protection as compared to vacuum packaging. Off-flavours as a result of irradiation of salted cooked meat products varied from slight to strong and depended on the type of product

  5. Allergic contact dermatitis from ophthalmic products: can pre-treatment with sodium lauryl sulfate increase patch test sensitivity?

    Science.gov (United States)

    Corazza, Monica; Virgili, Annarosa

    2005-05-01

    In patients suspected of allergic contact dermatitis because of topical ophthalmic medicaments, patch tests performed with patients' own products are often negative. The irritant anionic surfactant sodium lauryl sulfate (SLS) may alter the stratum corneum and increase antigen penetration. Pre-treatment of the skin with SLS 0.5% for 24 h was performed in the sites of patch tests with patients' own products in 15 selected patients. In patients previously negative to their own products tested with conventional patch tests, SLS pre-treatment showed 6 new relevant positive reactions and induced a stronger positive reaction in 1 patient. SLS pre-treatment could be proposed as an alternative promising method, which may increase sensitivity of patch tests with patients' own products.

  6. Estimating post-marketing exposure to pharmaceutical products using ex-factory distribution data.

    Science.gov (United States)

    Telfair, Tamara; Mohan, Aparna K; Shahani, Shalini; Klincewicz, Stephen; Atsma, Willem Jan; Thomas, Adrian; Fife, Daniel

    2006-10-01

    The pharmaceutical industry has an obligation to identify adverse reactions to drug products during all phases of drug development, including the post-marketing period. Estimates of population exposure to pharmaceutical products are important to the post-marketing surveillance of drugs, and provide a context for assessing the various risks and benefits, including drug safety, associated with drug treatment. This paper describes a systematic approach to estimating post-marketing drug exposure using ex-factory shipment data to estimate the quantity of medication available, and dosage information (stratified by indication or other factors as appropriate) to convert the quantity of medication to person time of exposure. Unlike the non-standardized methods often used to estimate exposure, this approach provides estimates whose calculations are explicit, documented, and consistent across products and over time. The methods can readily be carried out by an individual or small group specializing in this function, and lend themselves to automation. The present estimation approach is practical and relatively uncomplicated to implement. We believe it is a useful innovation. Copyright 2006 John Wiley & Sons, Ltd.

  7. Salmon louse (Lepeophtheirus salmonis transcriptomes during post molting maturation and egg production, revealed using EST-sequencing and microarray analysis

    Directory of Open Access Journals (Sweden)

    Jonassen Inge

    2008-03-01

    Full Text Available Abstract Background Lepeophtheirus salmonis is an ectoparasitic copepod feeding on skin, mucus and blood from salmonid hosts. Initial analysis of EST sequences from pre adult and adult stages of L. salmonis revealed a large proportion of novel transcripts. In order to link unknown transcripts to biological functions we have combined EST sequencing and microarray analysis to characterize female salmon louse transcriptomes during post molting maturation and egg production. Results EST sequence analysis shows that 43% of the ESTs have no significant hits in GenBank. Sequenced ESTs assembled into 556 contigs and 1614 singletons and whenever homologous genes were identified no clear correlation with homologous genes from any specific animal group was evident. Sequence comparison of 27 L. salmonis proteins with homologous proteins in humans, zebrafish, insects and crustaceans revealed an almost identical sequence identity with all species. Microarray analysis of maturing female adult salmon lice revealed two major transcription patterns; up-regulation during the final molting followed by down regulation and female specific up regulation during post molting growth and egg production. For a third minor group of ESTs transcription decreased during molting from pre-adult II to immature adults. Genes regulated during molting typically gave hits with cuticula proteins whilst transcripts up regulated during post molting growth were female specific, including two vitellogenins. Conclusion The copepod L.salmonis contains high a level of novel genes. Among analyzed L.salmonis proteins, sequence identities with homologous proteins in crustaceans are no higher than to homologous proteins in humans. Three distinct processes, molting, post molting growth and egg production correlate with transcriptional regulation of three groups of transcripts; two including genes related to growth, one including genes related to egg production. The function of the regulated

  8. Product design - Molecules, devices, functional products, and formulated products

    DEFF Research Database (Denmark)

    Gani, Rafiqul; Ng, Ka M.

    2015-01-01

    Chemical product design is a multidisciplinary and diverse subject. This article provides an overview of product design while focusing on product conceptualization. Four product types are considered - molecular products, formulated products, devices and functional products. For molecular products......, computer-aided design tools are used to predict the physicochemical properties of single molecules and blends. For formulated products, an integrated experiment-modeling approach is used to generate the formula with the specified product attributes. For devices and functional products, conceptual product...... design is carried out by modeling the product based on thermodynamics, kinetics and transport processes, by performing experiments, and by decision making based on rule-based methods The results are product specifications in terms of the type of ingredients, composition, and the structure, form, shape...

  9. How product trial changes quality perception of four new processed beef products

    DEFF Research Database (Denmark)

    Saeed, Faiza; Grunert, Klaus G; Therkildsen, Margrethe

    2013-01-01

    evaluation, quality evaluation and purchase motive fulfillment. For two of the tested products, trial resulted in a decline of the evaluation of cues, quality and purchase motive fulfillment compared to pre-trial expectations. For these products, positive expectations were created by giving information about...... and gender, which may be due to underlying differences in previous experience. The study gives useful insights for testing of new processed meat products before market introduction....

  10. Effect of certain production parameters and post-production treatments on the etching characteristics of CR-39 sheets

    Energy Technology Data Exchange (ETDEWEB)

    Somogyi, G.; Toth-Szilagyi, M.; Hunyadi, I.; Hafez, A.-F.

    1986-01-01

    There is a permanent need in producing track recording detectors of well defined behaviour from CR-39 monomer. Therefore, more studies on the role of production parameters determining the stability of main etching characteristics (bulk etch rate, Vsub(B);etch rate ratio, Vsub(T)/Vsub(B);opaqueness after longer etching periods) are highly required. In our studies we have examined different commercial CR-39 sheets (Homalite, Pershore, MA-ND) to compare their registration sensitivity to selected alpha and proton energies. In addition, we have investigated the main etching parameters of CR-39 sheets manufactured under different casting conditions varying the concentration of initiator and certain additives. Finally, the effect of some post-production treatments, annealing and storage in vacuum, on the Vsub(B) and Vsub(T)/Vsub(B) values is studied.

  11. An Overview of Production and Validation of the SMAP Passive Soil Moisture Product

    Science.gov (United States)

    Chan, S.; O'Neill, P.; Njoku, E.; Jackson, T.; Bindlish, R.

    2015-01-01

    The Soil Moisture Active Passive (SMAP) mission is an L-band mission scheduled for launch in Jan. 2015. The SMAP instruments consist of a radar and a radiometer to obtain complementary information from space for soil moisture and freeze/thaw state research and applications. By utilizing novel designs in antenna construction, retrieval algorithms, and acquisition hardware, SMAP provides a capability for global mapping of soil moisture and freeze/thaw state with unprecedented accuracy, resolution, and coverage. This improvement in hydrosphere state measurement is expected to advance our understanding of the processes that link the terrestrial water, energy and carbon cycles, improve our capability in flood prediction and drought monitoring, and enhance our skills in weather and climate forecast. For swath-based soil moisture measurement, SMAP generates three operational geophysical data products: (1) the radiometer-only soil moisture product (L2_SM_P) posted at 36-kilometer resolution, (2) the radar-only soil moisture product (L2_SM_A) posted at 3-kilometers resolution, and (3) the radar-radiometer combined soil moisture product (L2_SM_AP) posted at 9-kilometers resolution. Each product draws on the strengths of the underlying sensor(s) and plays a unique role in hydroclimatological and hydrometeorological applications. A full suite of SMAP data products is given in Table 1.

  12. Inhibition of ethanol-producing yeast and bacteria by degradation products produced during pre-treatment of biomass

    DEFF Research Database (Denmark)

    Klinke, H.B.; Thomsen, A.B.; Ahring, Birgitte Kiær

    2004-01-01

    for ethanol fermentation. The resulting hydrolyzsates contain substances inhibitory to fermentation-depending on both the raw material (biomass) and the pre-treatment applied. An overview of the inhibitory effect on ethanol production by yeast and bacteria is presented. Apart from furans formed by sugar......An overview of the different inhibitors formed by pre-treatment of lignocellulosic materials and their inhibition of ethanol production in yeast and bacteria is given. Different high temperature physical pre-treatment methods are available to render the carbohydrates in lignocellulose accessible...... degradation, phenol monomers from lignin degradation are important co-factors in hydrolysate inhibition, and inhibitory effects of these aromatic compounds on different ethanol producing microorganisms is reviewed. The furans and phenols generally inhibited growth and ethanol production rate (Q...

  13. Health Impacts from Corn Production Pre-and Post-NAFTA Trade Agreement (1986-2013).

    Science.gov (United States)

    Mendoza-Cano, Oliver; Sánchez-Piña, Ramón Alberto; González-Ibarra, Álvaro Jesús; Murillo-Zamora, Efrén; Nava-Garibaldi, Cynthia Monique

    2016-07-13

    Life cycle assessment (LCA) is a powerful methodology for the study of health impacts and public policies. We performed this study to quantitatively explain the potential health impacts on disability-adjusted life years (DALYs) of corn produced in Mexico and imported from the United States of America (U.S.) from 1984 until 2014. The processes are hybrid and organic corn production. The functional unit was defined as 1 ton of corn production. Results indicate a total value of 178,431, 244,175, and 283,426 DALYs of three decades: 1984-1993, 1994-2003, and 2004-2013, of Mexican production; the U.S. production and transport were also calculated, showing values of 29,815, 65,837, and 107,729 for the same three decades. Additionally, DALYs were obtained for the category of human health and climate change by functional unit: 802.31 (1984-1993), 802.67 (1994-2003), and 803.92 (2004-2013), and for imported corn transported to Mexico from the U.S., 859.12 (1984-2013). DALYs on human toxicity were obtained: 99.05 (1984-1993), 99.05 (1994-2003), and 99.04 (2004-2013), and for the corn imported and transported to Mexico from the U.S., 116.25 (1984-2013). Environmental and health impacts in terms of DALYs are higher when corn is imported versus the corn produced in Mexico. Environmental health and nominal corn cultivation and transport impacts have increased as a result of the North American Free Trade Agreement (NAFTA). Mexico needs to redefine its public policies to suffer less of an environmental burden from corn to ensure global environmental health and food security.

  14. Free ammonia pre-treatment of secondary sludge significantly increases anaerobic methane production.

    Science.gov (United States)

    Wei, Wei; Zhou, Xu; Wang, Dongbo; Sun, Jing; Wang, Qilin

    2017-07-01

    Energy recovery in the form of methane from sludge/wastewater is restricted by the poor and slow biodegradability of secondary sludge. An innovative pre-treatment technology using free ammonia (FA, i.e. NH 3 ) was proposed in this study to increase anaerobic methane production. The solubilisation of secondary sludge was significantly increased after FA pre-treatment at up to 680 mg NH 3 -N/L for 1 day, under which the solubilisation (i.e. 0.4 mg SCOD/mg VS; SCOD: soluble chemical oxygen demand; VS: volatile solids) was >10 times higher than that without FA pre-treatment (i.e. 0.03 mg SCOD/mg VS). Biochemical methane potential assays showed that FA pre-treatment at above 250 mg NH 3 -N/L is effective in improving anaerobic methane production. The highest improvement in biochemical methane potential (B 0 ) and hydrolysis rate (k) was achieved at FA concentrations of 420-680 mg NH 3 -N/L, and was determined as approximately 22% (from 160 to 195 L CH 4 /kg VS added) and 140% (from 0.22 to 0.53 d -1 ) compared to the secondary sludge without pre-treatment. More analysis revealed that the FA induced improvement in B 0 and k could be attributed to the rapidly biodegradable substances rather than the slowly biodegradable substances. Economic and environmental analyses showed that the FA-based technology is economically favourable and environmentally friendly. Since this FA technology aims to use the wastewater treatment plants (WWTPs) waste (i.e. anaerobic digestion liquor) to enhance methane production from the WWTPs, it will set an example for the paradigm shift of the WWTPs from 'linear economy' to 'circular economy'. Copyright © 2017 Elsevier Ltd. All rights reserved.

  15. Post-Menopausal Vaginal Hemorrhage Related to the Use of a Hop-Containing Phytotherapeutic Product

    NARCIS (Netherlands)

    van Hunsel, Florence; van de Koppel, Sonja; van Puijenbroek, Eugène

    2015-01-01

    Two 54-year-old women developed abdominal cramps and vaginal hemorrhage as a result of endometrial hyperplasia during treatment with a hop-containing phytotherapeutic product (MenoCool®) for post-menopausal complaints. The women used the hop-containing phytotherapeutic product (418 mg of hop per

  16. Peptidoglycan inhibits progesterone and androstenedione production in bovine ovarian theca cells.

    Science.gov (United States)

    Magata, F; Horiuchi, M; Miyamoto, A; Shimizu, T

    2014-08-01

    Uterine bacterial infection perturbs uterine and ovarian functions in postpartum dairy cows. Peptidoglycan (PGN) produced by gram-positive bacteria has been shown to disrupt the ovarian function in ewes. The aim of this study was to determine the effect of PGN on steroid production in bovine theca cells at different stages of follicular development. Bovine theca cells isolated from pre- and post-selection ovarian follicles (8.5mm in diameter, respectively) were cultured in vitro and challenged with PGN. Steroid production was evaluated by measuring progesterone (P4) and androstenedione (A4) concentration in culture media after 48 h or 96 h of culture. Bovine theca cells expressed PGN receptors including Toll-like receptor 2 and nucleotide-binding oligomerization domain 1 and 2. Treatment with PGN (1, 10, or 50 μg/ml) led to a decrease in P4 and A4 production by theca cells in both pre- and post-selection follicles. The mRNA expression of steroidogenic enzymes were decreased by PGN treatment. Moreover, A4 production was further suppressed when theca cells of post-selection follicles were simultaneously treated by PGN and lipopolysaccharide (0.1, 1, or 10 μg/ml). These findings indicate that bacterial toxins may act locally on ovarian steroidogenic cells and compromise follicular development in postpartum dairy cows. Copyright © 2014 Elsevier Ltd. All rights reserved.

  17. Scientific data products and the data pre-processing subsystem of the Chang'e-3 mission

    International Nuclear Information System (INIS)

    Tan Xu; Liu Jian-Jun; Li Chun-Lai; Feng Jian-Qing; Ren Xin; Wang Fen-Fei; Yan Wei; Zuo Wei; Wang Xiao-Qian; Zhang Zhou-Bin

    2014-01-01

    The Chang'e-3 (CE-3) mission is China's first exploration mission on the surface of the Moon that uses a lander and a rover. Eight instruments that form the scientific payloads have the following objectives: (1) investigate the morphological features and geological structures at the landing site; (2) integrated in-situ analysis of minerals and chemical compositions; (3) integrated exploration of the structure of the lunar interior; (4) exploration of the lunar-terrestrial space environment, lunar surface environment and acquire Moon-based ultraviolet astronomical observations. The Ground Research and Application System (GRAS) is in charge of data acquisition and pre-processing, management of the payload in orbit, and managing the data products and their applications. The Data Pre-processing Subsystem (DPS) is a part of GRAS. The task of DPS is the pre-processing of raw data from the eight instruments that are part of CE-3, including channel processing, unpacking, package sorting, calibration and correction, identification of geographical location, calculation of probe azimuth angle, probe zenith angle, solar azimuth angle, and solar zenith angle and so on, and conducting quality checks. These processes produce Level 0, Level 1 and Level 2 data. The computing platform of this subsystem is comprised of a high-performance computing cluster, including a real-time subsystem used for processing Level 0 data and a post-time subsystem for generating Level 1 and Level 2 data. This paper describes the CE-3 data pre-processing method, the data pre-processing subsystem, data classification, data validity and data products that are used for scientific studies

  18. Fire intensity impacts on post-fire temperate coniferous forest net primary productivity

    Science.gov (United States)

    Sparks, Aaron M.; Kolden, Crystal A.; Smith, Alistair M. S.; Boschetti, Luigi; Johnson, Daniel M.; Cochrane, Mark A.

    2018-02-01

    Fire is a dynamic ecological process in forests and impacts the carbon (C) cycle through direct combustion emissions, tree mortality, and by impairing the ability of surviving trees to sequester carbon. While studies on young trees have demonstrated that fire intensity is a determinant of post-fire net primary productivity, wildland fires on landscape to regional scales have largely been assumed to either cause tree mortality, or conversely, cause no physiological impact, ignoring the impacted but surviving trees. Our objective was to understand how fire intensity affects post-fire net primary productivity in conifer-dominated forested ecosystems on the spatial scale of large wildland fires. We examined the relationships between fire radiative power (FRP), its temporal integral (fire radiative energy - FRE), and net primary productivity (NPP) using 16 years of data from the MOderate Resolution Imaging Spectrometer (MODIS) for 15 large fires in western United States coniferous forests. The greatest NPP post-fire loss occurred 1 year post-fire and ranged from -67 to -312 g C m-2 yr-1 (-13 to -54 %) across all fires. Forests dominated by fire-resistant species (species that typically survive low-intensity fires) experienced the lowest relative NPP reductions compared to forests with less resistant species. Post-fire NPP in forests that were dominated by fire-susceptible species were not as sensitive to FRP or FRE, indicating that NPP in these forests may be reduced to similar levels regardless of fire intensity. Conversely, post-fire NPP in forests dominated by fire-resistant and mixed species decreased with increasing FRP or FRE. In some cases, this dose-response relationship persisted for more than a decade post-fire, highlighting a legacy effect of fire intensity on post-fire C dynamics in these forests.

  19. Critical Assessment of Video Production in Teacher Education: Can Video Production Foster Community-Engaged Scholarship?

    Science.gov (United States)

    Yang, Kyung-Hwa

    2014-01-01

    In the theoretical framework of production pedagogy, I reflect on a video production project conducted in a teacher education program and discuss the potential of video production to foster community-engaged scholarship among pre-service teachers. While the importance of engaging learners in creating media has been emphasized, studies show little…

  20. Extended Producer Responsibility and Product Stewardship for Tobacco Product Waste.

    Science.gov (United States)

    Curtis, Clifton; Collins, Susan; Cunningham, Shea; Stigler, Paula; Novotny, Thomas E

    2014-09-01

    This paper reviews several environmental principles, including Extended Producer Responsibility (EPR), Product Stewardship (PS), the Polluter Pays Principle (PPP), and the Precautionary Principle, as they may apply to tobacco product waste (TPW). The review addresses specific criteria that apply in deciding whether a particular toxic product should adhere to these principles; presents three case studies of similar approaches to other toxic and/or environmentally harmful products; and describes 10 possible interventions or policy actions that may help prevent, reduce, and mitigate the effects of TPW. EPR promotes total lifecycle environmental improvements, placing economic, physical, and informational responsibilities onto the tobacco industry, while PS complements EPR, but with responsibility shared by all parties involved in the tobacco product lifecycle. Both principles focus on toxic source reduction, post-consumer take-back, and final disposal of consumer products. These principles when applied to TPW have the potential to substantially decrease the environmental and public health harms of cigarette butts and other TPW throughout the world. TPW is the most commonly littered item picked up during environmental, urban, and coastal cleanups globally.

  1. Determination of pre-cecal phosphorus digestibility of inorganic phosphates and bone meal products in broilers.

    Science.gov (United States)

    van Harn, J; Spek, J W; van Vuure, C A; van Krimpen, M M

    2017-05-01

    A broiler study was performed to determine the pre-cecal phosphorus (P) digestibility of 5 P sources, 3 from animal (Delfos, Calfos, and porcine bone meal) and 2 of inorganic (monocalcium phosphate [MCP] and dicalcium phosphate [DCP]) origin. Delfos is processed from bones resulting in a dicalcium phosphate product, and Calfos is processed from bones in which part of the gelatin is removed but in which the hydroxy-apatite matrix is preserved. During the first 14 d, birds were housed in floor pens bedded with wood shavings and received a commercial starter diet. At d 14, broilers were randomly assigned to pens (0.9 m2, 10 birds/pen) with a slatted floor. From d 14 onwards, one of the 6 experimental diets (a basal diet, and 5 diets containing the P sources) was provided. Test diets were replicated 6 times, and the basal diet 8 times. Electron microscopy images of test products were made in order to verify whether the spatial structure of the test products could be related to the pre-cecal P digestibility of the same products. Diets met or exceeded CVB (2011) requirements for all nutrients except for P and were formulated to contain a calcium to total P ratio of between 1.4 and 1.6 and a minimal amount of phytate P. Diets contained 5 g/kg titanium oxide as a marker to determine digestibility of P. At d 24 all birds were euthanized, after which the content of the terminal part of the ileum was sampled. The P digestibility was calculated by linear regression according to World's Poultry Science Association (WPSA) protocol for determination of pre-cecal P digestibility. Pre-cecal P digestibility of MCP, DCP, Delfos, Calfos, and porcine bone meal was 88.5, 82.4, 94.5, 86.9, and 78.2%, respectively. Based on visual inspection of electron microscopy images of test products, the spatial structure of the test products might be related to P digestibility. It is concluded that processing of bone meal increases the pre-cecal P digestibility in broilers. © The Author 2017

  2. Empirical Productivity Indices and Indicators

    NARCIS (Netherlands)

    B.M. Balk (Bert)

    2016-01-01

    textabstractThe empirical measurement of productivity change (or difference) by means of indices and indicators starts with the ex post profit/loss accounts of a production unit. Key concepts are profit, leading to indicators, and profitability, leading to indices. The main task for the productivity

  3. ESTIMATION OF EFFICIENCY OF MACHINERY FOR PRE-SOWING TREATMENT OF RADISH SEEDS FOR SEED PRODUCTION

    Directory of Open Access Journals (Sweden)

    S. M. Sirota

    2016-01-01

    Full Text Available The results of pre-sowing treatment of radish seeds aimed at increasing of seed production, yield and its productivity in protected area are presented. The density fractionation of radish seeds by gravity separator is recommended for improvement of planting material quality and increasing of utilization efficiency of frame area.

  4. Bidirectional transfer between joint and individual actions in a task of discrete force production.

    Science.gov (United States)

    Masumoto, Junya; Inui, Nobuyuki

    2017-07-01

    The present study examined bidirectional learning transfer between joint and individual actions involving discrete isometric force production with the right index finger. To examine the effects of practice of joint action on performance of the individual action, participants performed a pre-test (individual condition), practice blocks (joint condition), and a post-test (individual condition) (IJI task). To examine the effects of practice of the individual action on performance during the joint action, the participants performed a pre-test (joint condition), practice blocks (individual condition), and a post-test (joint condition) (JIJ task). Whereas one participant made pressing movements with a target peak force of 10% maximum voluntary contraction (MVC) in the individual condition, two participants produced the target force of the sum of 10% MVC produced by each of them in the joint condition. In both the IJI and JIJ tasks, absolute errors and standard deviations of peak force were smaller post-test than pre-test, indicating bidirectional transfer between individual and joint conditions for force accuracy and variability. Although the negative correlation between forces produced by two participants (complementary force production) became stronger with practice blocks in the IJI task, there was no difference between the pre- and post-tests for the negative correlation in the JIJ task. In the JIJ task, the decrease in force accuracy and variability during the individual action did not facilitate complementary force production during the joint action. This indicates that practice performed by two people is essential for complementary force production in joint action.

  5. GPM Ground Validation: Pre to Post-Launch Era

    Science.gov (United States)

    Petersen, Walt; Skofronick-Jackson, Gail; Huffman, George

    2015-04-01

    NASA GPM Ground Validation (GV) activities have transitioned from the pre to post-launch era. Prior to launch direct validation networks and associated partner institutions were identified world-wide, covering a plethora of precipitation regimes. In the U.S. direct GV efforts focused on use of new operational products such as the NOAA Multi-Radar Multi-Sensor suite (MRMS) for TRMM validation and GPM radiometer algorithm database development. In the post-launch, MRMS products including precipitation rate, accumulation, types and data quality are being routinely generated to facilitate statistical GV of instantaneous (e.g., Level II orbit) and merged (e.g., IMERG) GPM products. Toward assessing precipitation column impacts on product uncertainties, range-gate to pixel-level validation of both Dual-Frequency Precipitation Radar (DPR) and GPM microwave imager data are performed using GPM Validation Network (VN) ground radar and satellite data processing software. VN software ingests quality-controlled volumetric radar datasets and geo-matches those data to coincident DPR and radiometer level-II data. When combined MRMS and VN datasets enable more comprehensive interpretation of both ground and satellite-based estimation uncertainties. To support physical validation efforts eight (one) field campaigns have been conducted in the pre (post) launch era. The campaigns span regimes from northern latitude cold-season snow to warm tropical rain. Most recently the Integrated Precipitation and Hydrology Experiment (IPHEx) took place in the mountains of North Carolina and involved combined airborne and ground-based measurements of orographic precipitation and hydrologic processes underneath the GPM Core satellite. One more U.S. GV field campaign (OLYMPEX) is planned for late 2015 and will address cold-season precipitation estimation, process and hydrology in the orographic and oceanic domains of western Washington State. Finally, continuous direct and physical validation

  6. Assessment of tobacco heating product THP1.0. Part 9: The placement of a range of next-generation products on an emissions continuum relative to cigarettes via pre-clinical assessment studies.

    Science.gov (United States)

    Murphy, James; Liu, Chuan; McAdam, Kevin; Gaҫa, Marianna; Prasad, Krishna; Camacho, Oscar; McAughey, John; Proctor, Christopher

    2018-03-01

    This series of nine papers described the operation and pre-clinical assessment of a tobacco heating product THP1.0. This last paper contextualises the pre-clinical assessment data on THP1.0 with data from other next generation products relative to cigarette smoke. The tobacco and nicotine risk continuum is a concept that ranks products according to their potential harm, with cigarettes at the highest risk extreme and Nicotine Replacement Therapy at the least risky extreme. Data generated in pre-clinical studies on THP1.0 and a range of Next Generation Products (NGPs) may provide some initial indication of potential ranking of these products, although importantly, data from such studies are limited and cannot take into consideration several important aspects for risk such as long term product use patterns. In each of the studies, the responses to the emissions from THP1.0 were substantially reduced relative to cigarette smoke. Additionally, responses from THP1.0 were very similar to those from the other NGP emissions. A comparison of the results clearly showed the emissions from all the NGPs were considerably lower than those from cigarettes and all in around the same emissions level. These results show that THP1.0 could have the potential to be a reduced risk product compared to cigarettes, though further studies assessing the exposure, individual and population risk reduction profile would be required to substantiate this potential. Copyright © 2017 The Authors. Published by Elsevier Inc. All rights reserved.

  7. Advantages of pre-production WLCG/EGEE services for VOs and users

    CERN Document Server

    Thackray, N; Fernandez Sanchez, C; Freire Garcia, E; Simon Garcia, A; Lopez Cacheiro, J

    2008-01-01

    The benefits that the Pre-Production Service (PPS) can offer to VOs and new users will be shown. Current PPS processes will be described so they have a better understanding of the PPS environment. PPS offers a proper place where VOs can test their applications and check their compatibility with upcoming middleware releases. PPS could help VOs improve their applications and at the same time, VOs would be helping PPS to produce better tested middleware releases that would go into Production (PROD) Currently a well-defined set of procedures is followed in PPS, beginning with the pre-deployment activity and finishing with the approval of a new middleware release that can go into PROD. The PPS Coordination Team takes care of supervising all these steps, mainly trying to spot possible bugs in the middleware before it goes into PROD. Unfortunately, VO contribution in this part of the deployment is currently very limited and the PPS team does not have a full feedback from these important groups. One of the problems i...

  8. Process for calcium xylonate production as a concrete admixture derived from in-situ fermentation of wheat straw pre-hydrolysate.

    Science.gov (United States)

    Zhou, Xin; Zhou, Xuelian; Tang, Xiusheng; Xu, Yong

    2018-08-01

    One of the major obstacles in process of lignocellulosic biorefinery is the utilization of pre-hydrolysate from pre-treatment. Although lignocellulosic pre-hydrolysate can serve as an economic starting material for xylonic acid production, the advancement of xylonic acid or xylonate is still limited by further commercial value or applications. In the present study, xylose in the high concentration wheat straw pre-hydrolysate was first in-situ biooxidized to xylonate by Gluconobacter oxydans. To meet the needs of commercialization, crude powdered calcium xylonate was prepared by drying process and calcium xylonate content in the prepared crude product was more than 70%. Then, the calcium xylonate product was evaluated as concrete admixture without any complex purification steps and the results demonstrated that xylonate could improve the performance of concrete. Overall, the crude xylonate product directly produced from low-cost wheat straw pre-hydrolysate can potentially be developed as retarding reducer, which could subsequently benefit lignocellulosic biorefinery. Copyright © 2018 Elsevier Ltd. All rights reserved.

  9. Production and requirements for pre-basic seed potato material in the Republic of Serbia and the Republic of Srpska

    Directory of Open Access Journals (Sweden)

    Milošević Drago

    2012-01-01

    Full Text Available Pre-basic seed potato material is used for basic seed (elite and certified seed potato production. At this moment all basic seed material is imported into Republic of Serbia and Republic of Srpska, despite the fact that the method of in vitro tissue culture production of virus-free seed potato has been developed in both countries and there is a continuous demand for pre-basic and basic seed potato. Current total production is significantly lower than actual requirements. In the 80s and 90s of the previous century two modern facilities for production of virus-free seed potato and certified seed were built in Sokolac (Republic of Srpska and Guča (Republic of Serbia. Although facilities were well-equipped, seed potato production was permanently ceased in 2000. The presence of high infection pressure dominated by potato virus Y is shown in the Republic of Serbia and the Republic of Srpska. This paper gives an overview of pre-basic seed potato material production in both countries over the last two decades.

  10. The effect of dilute acid pre-treatment process in bioethanol production from durian (Durio zibethinus) seeds waste

    Science.gov (United States)

    Ghazali, K. A.; Salleh, S. F.; Riayatsyah, T. M. I.; Aditiya, H. B.; Mahlia, T. M. I.

    2016-03-01

    Lignocellulosic biomass is one of the promising feedstocks for bioethanol production. The process starts from pre-treatment, hydrolysis, fermentation, distillation and finally obtaining the final product, ethanol. The efficiency of enzymatic hydrolysis of cellulosic biomass depends heavily on the effectiveness of the pre-treatment step which main function is to break the lignin structure of the biomass. This work aims to investigate the effects of dilute acid pre-treatment on the enzymatic hydrolysis of durian seeds waste to glucose and the subsequent bioethanol fermentation process. The yield of glucose from dilute acid pre-treated sample using 0.6% H2SO4 and 5% substrate concentration shows significant value of 23.4951 g/L. Combination of dilute acid pre-treatment and enzymatic hydrolysis using 150U of enzyme able to yield 50.0944 g/L of glucose content higher compared to normal pre-treated sample of 8.1093 g/L. Dilute acid pre-treatment sample also shows stable and efficient yeast activity during fermentation process with lowest glucose content at 2.9636 g/L compared to 14.7583g/L for normal pre-treated sample. Based on the result, it can be concluded that dilute acid pre-treatment increase the yield of ethanol from bioethanol production process.

  11. Sound post production in advertising and in the film, case study of Studio Beep s.r.o.

    OpenAIRE

    Struhařová, Michaela

    2012-01-01

    Main topic of this thesis is description of sound post production in advertising and in the film film industry and making case study of company Studio Beep s.r.o. First aim of this thesis is describe as clearly as possible the theory of sound and sound post production in advertising and in film industry and also show specifics accompanying production of sound in each discipline. The theoretical part contains basic overview about history of sound, sound dramaturgy and about general principles ...

  12. Effect of ultrasound pre-treatment on the physicochemical composition of Agave durangensis leaves and potential enzyme production.

    Science.gov (United States)

    Contreras-Hernández, M G; Ochoa-Martínez, L A; Rutiaga-Quiñones, J G; Rocha-Guzmán, N E; Lara-Ceniceros, T E; Contreras-Esquivel, J C; Prado Barragán, L A; Rutiaga-Quiñones, O M

    2018-02-01

    Approximately 1 million tons of agave plants are processed annually by the Mexican tequila and mezcal industry, generating vast amounts of agroindustrial solid waste. This type of lignocellulosic biomass is considered to be agroindustrial residue, which can be used to produce enzymes, giving it added value. However, the structure of lignocellulosic biomass makes it highly recalcitrant, and results in relatively low yield when used in its native form. The aim of this study was to investigate an effective pre-treatment method for the production of commercially important hydrolytic enzymes. In this work, the physical and chemical modification of Agave durangensis leaves was analysed using ultrasound and high temperature as pre-treatments, and production of enzymes was evaluated. The pre-treatments resulted in modification of the lignocellulosic structure and composition; the ultrasound pre-treatment improved the production of inulinase by 4 U/mg and cellulase by 0.297 U/mg, and thermal pre-treatment improved β-fructofuranosidase by 30 U/mg. Copyright © 2017 Elsevier Ltd. All rights reserved.

  13. Immunization and Hedging of Post Retirement Income Annuity Products

    Directory of Open Access Journals (Sweden)

    Changyu Liu

    2017-03-01

    Full Text Available Designing post retirement benefits requires access to appropriate investment instruments to manage the interest rate and longevity risks. Post retirement benefits are increasingly taken as a form of income benefit, either as a pension or an annuity. Pension funds and life insurers offer annuities generating long term liabilities linked to longevity. Risk management of life annuity portfolios for interest rate risks is well developed but the incorporation of longevity risk has received limited attention. We develop an immunization approach and a delta-gamma based hedging approach to manage the risks of adverse portfolio surplus using stochastic models for mortality and interest rates. We compare and assess the immunization and hedge effectiveness of fixed-income coupon bonds, annuity bonds, as well as longevity bonds, using simulations of the portfolio surplus for an annuity portfolio and a range of risk measures including value-at-risk. We show how fixed-income annuity bonds can more effectively match cash flows and provide additional hedge effectiveness over coupon bonds. Longevity bonds, including deferred longevity bonds, reduce risk significantly compared to coupon and annuity bonds, reflecting the long duration of the typical life annuity and the exposure to longevity risk. Longevity bonds are shown to be effective in immunizing surplus over short and long horizons. Delta gamma hedging is generally only effective over short horizons. The results of the paper have implications for how providers of post retirement income benefit streams can manage risks in demanding conditions where innovation in investment markets can support new products and increase the product range.

  14. Modelling Product Families for Product Configuration Systems with Product Variant Master

    DEFF Research Database (Denmark)

    Mortensen, Niels Henrik; Hvam, Lars; Haug, Anders

    2010-01-01

    This article presents an evaluation of applying a suggested method for modelling product families for product configuration based on theory for modelling mechanical products,systems theory and object-oriented modelling. The modelling technique includes a so-called product variant master and CRC-cards...... the three views. Modelling of characteristics of the product variants in a product family Modelling of constraints between parts in the product family Visualisation of the entire product family on a poster e.g. 1x2 meters The product variant master and CRC-cards are means to bridge the gap between domain...... experts and IT-developers, thus making it possible for the domain experts (e.g. engineers from product development) to express their knowledge in a form that is understandable both for the domain experts and the IT-developers. The product variant master and CRC-cards have currently been tested and further...

  15. Influences of geo-spatial location on pre-exposure prophylaxis use in South Africa: positioning microbicides for better product uptake.

    Science.gov (United States)

    Govender, Eliza M; Mansoor, Leila E; Abdool Karim, Quarraisha

    2017-06-01

    Young women bear a disproportionately high burden of HIV infection in sub-Saharan Africa, prioritising pre-exposure prophylaxis (PrEP) can be an integral part of HIV prevention combination strategies. Women initiated HIV prevention technology options will require consistent adherence, an imperative for product effectiveness. With several PrEP clinical trials underway; exploring women's acceptability to advances in HIV prevention technologies can better facilitate demand creation for future PrEP roll out. This study utilised the opportunity of post-trial access to CAPRISA 008 women (trial) and non-trial women from three geo-spatial settings (urban, rural and peri-urban) to identify microbicide acceptability and how product associations of microbicides can influence future HIV prevention choices. Six participatory workshops using participatory action research with art-based activities and discussion groups were conducted in KwaZulu-Natal with 104 women from various geo-spatial locations and social status to understand microbicide acceptability and product associations. The data were analysed using thematic analysis. The study found that women's acceptability and product association of the tenofovir gel microbicide differed according to rural and urban areas. Most urban women identified confidence, sexiness and classiness as key associations that will encourage microbicide acceptability and use, while rural women identified respect, responsibility and confidence as the key product associations, with increased focus on the individual and collective family/community benefits of product acceptance and use. Urban-rural differences suggest a market segmentation that is contextualised to be locally responsive to promote HIV prevention technologies. Various sexual encounters further determined the types of HIV prevention technologies women would consider. In line with WHO's recommendation that PrEP should be an additional prevention choice for people at risk of HIV, this

  16. Factors affecting the water holding capacity of red meat products: a review of recent research advances.

    Science.gov (United States)

    Cheng, Qiaofen; Sun, Da-Wen

    2008-02-01

    The water holding capacity of meat products is a very important quality attribute which has an influence on product yield, which in turn has economic implications, but is also important in terms of eating quality. A number of pre-and post-mortem factors influence the water holding capacity (WHC) of meat. During the growth and development of meat animals, genotype and animal diet are important due to their direct influence on muscle characteristics. In the immediate pre-slaughter period, stresses on the animal such as fasting, and different stunning methods are likely to influence meat WHC. In the post-slaughter period chilling, ageing, injecting non-meat ingredients, as well as tumbling have important influences on WHC. Furthermore, cooking and cooling procedures for the final meat products can also affect the WHC of the product, in particular the cooking and the cooling methods, the heating and the cooling rate, the cooking temperature, and the endpoint temperature. This paper provides an overview of recent research on important intrinsic and extrinsic factors that affect the WHC of beef, pork, and lamb products, and reveals explanations and solutions to some of the critical problems related to WHC and product quality.

  17. Anaerobic digestion of organic by-products from meat-processing industry. The effect of pre-treatments and co-digestion

    Energy Technology Data Exchange (ETDEWEB)

    Luste, S.

    2011-07-01

    Anaerobic digestion is a multi-beneficial biological treatment during which micro-organisms degrade organic material producing biogas (i.e. methane) and stabilised end-product (i.e. digestate). Methane is a versatile renewable energy source and digestate can be used as an organic fertiliser and/or soil improver. Because of the increasing consumption and tightening environment and health legislation, production of organic wastes suitable for anaerobic digestion increases. Animal by-products (ABP) from the meat-processing industry are often rendered (contaminated material), used as feedstock (in fur breeding), or composted. However, ABPs studied could not be utilised in fodder or in animal food production and have currently been rendered or directed to composting, despite being mostly considered unsuitable for composting. Many ABPs are energy-rich, wet and pasty materials and suitable for the anaerobic digestion process. Moreover, suitable pre-treatment to hydrolyse solid materials and/or co-digestion of two or several materials may improve the anaerobic digestion with ultimate goal to increase the methane production, stabilisation and reusability of digestate. The case chosen for more detailed research was that of a middle-sized Finnish meat-processing industry. The aim of the thesis was to evaluate the feasibility of different ABPs presently available for treatment as raw material for anaerobic digestion. Another objective was to enhance the anaerobic digestion process via specific pre-treatments and co-digestion cases with the ultimate aim to increase the methane production and the quality of the digestate. The general goal was to observe the overall process from the perspective of real-circumstances in Finland to rise to needs in practice and to produce exploitable information for adopting sustainable development locally and case-specifically into practice via versatile anaerobic digestion technology. The ABPs studied were highly bio-degradable and especially

  18. Health Impacts from Corn Production Pre-and Post-NAFTA Trade Agreement (1986–2013)

    Science.gov (United States)

    Mendoza-Cano, Oliver; Sánchez-Piña, Ramón Alberto; González-Ibarra, Álvaro Jesús; Murillo-Zamora, Efrén; Nava-Garibaldi, Cynthia Monique

    2016-01-01

    Life cycle assessment (LCA) is a powerful methodology for the study of health impacts and public policies. We performed this study to quantitatively explain the potential health impacts on disability-adjusted life years (DALYs) of corn produced in Mexico and imported from the United States of America (U.S.) from 1984 until 2014. The processes are hybrid and organic corn production. The functional unit was defined as 1 ton of corn production. Results indicate a total value of 178,431, 244,175, and 283,426 DALYs of three decades: 1984–1993, 1994–2003, and 2004–2013, of Mexican production; the U.S. production and transport were also calculated, showing values of 29,815, 65,837, and 107,729 for the same three decades. Additionally, DALYs were obtained for the category of human health and climate change by functional unit: 802.31 (1984–1993), 802.67 (1994–2003), and 803.92 (2004–2013), and for imported corn transported to Mexico from the U.S., 859.12 (1984–2013). DALYs on human toxicity were obtained: 99.05 (1984–1993), 99.05 (1994–2003), and 99.04 (2004–2013), and for the corn imported and transported to Mexico from the U.S., 116.25 (1984–2013). Conclusions: Environmental and health impacts in terms of DALYs are higher when corn is imported versus the corn produced in Mexico. Environmental health and nominal corn cultivation and transport impacts have increased as a result of the North American Free Trade Agreement (NAFTA). Mexico needs to redefine its public policies to suffer less of an environmental burden from corn to ensure global environmental health and food security. PMID:27420088

  19. Production of Modularised Product Systems

    DEFF Research Database (Denmark)

    Jacobsen, Peter

    2004-01-01

    but a solution. Modularisation is one tool used in designing the products. Designing and controlling a production system making customized products in an economical way is not an easy task. In order to fulfil the Lean and Agile manufacturing philosophies the production is often carried out in networks. Here...

  20. Fission Product Library and Resource

    Energy Technology Data Exchange (ETDEWEB)

    Burke, J. T. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Padgett, S. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

    2016-09-29

    Fission product yields can be extracted from an irradiated sample by performing gamma ray spectroscopy on the whole sample post irradiation. There are several pitfalls to avoid when trying to determine a specific isotope's fission product yield.

  1. Assessment of the Kid Production Traits of Kacang Goat under Smallholders Production System

    Directory of Open Access Journals (Sweden)

    A Priyono

    2010-05-01

    Full Text Available The main objectives of this study were to assess the influence of environmental (non-genetic factors on kid production traits of Kacang goat under smallholders production system. The study was conducted at the Kacang goat smallholders, located at the centre of Kacang goat in Gundi subdistric, Purwodadi regency, Central Java. The kid production traits evaluated are birth weight, weaning weight, and growth rate till weaning. The environmental factors assessed were: sex (male, female, type of birth (singles, twins, triplets and dam’s parity (1-7. Data were analysed statistically according to the analysis of variance procedure using the General Linear Model (GLM. Least squares analysis revealed that dam’s parity, birth type, and sex of kid were significant sources of variation for birth and weaning weight and pre weaning growth in Kacang kids. The average birth weight, weaning weight and pre weaning growth of males (2.07±0.02 kg; 10.457±0.1 kg; 69.35±0.73 g/d were found to be higher than females (1.95±0.02 kg; 9.15±0.09 kg; 60.73±0.71 g/d. Kid production traits increased with parity, with the largest values at the fourth parity and then slightly decreased thereafter. The average male and female birth weight (2.18+0.03 kg; 2.02+0.03 kg, weaning weight (10.72+0.11 and 9.39+0.13 kg and pre weaning growth (71.63+0.79 and 62.21+0.96 g/d of single kids were heavier than twins, and triplets indicating the influence of the mothering ability of doe. It was recommended, the farmers should consider maternal ability for improvement of weaning weight and growth rate of Kacang kids. (Animal Production 12(2: 111-116 (2010Key Words: Kacang goat, kid production, birth weight, weaning weight, growth rate

  2. Detection of relevant amounts of cow's milk protein in non-pre-packed bakery products sold as cow's milk-free.

    Science.gov (United States)

    Trendelenburg, V; Enzian, N; Bellach, J; Schnadt, S; Niggemann, B; Beyer, K

    2015-05-01

    Currently, there is no mandatory labelling of allergens for non-pre-packed foods in the EU. Therefore, consumers with food allergy rely on voluntary information provided by the staff. The aim of this study was to characterize allergic reactions to non-pre-packed foods and to investigate whether staff in bakery shops were able to give advice regarding a safe product choice. Questionnaires were sent to 200 parents of children with a food allergy. Staff of 50 bakery shops were interviewed regarding selling non-pre-packed foods to food-allergic customers. Bakery products being recommended as 'cow's milk-free' were bought, and cow's milk protein levels were measured using ELISA. A total of 104 of 200 questionnaires were returned. 25% of the children experienced an allergic reaction due to a non-pre-packed food from bakery shops and 20% from ice cream parlours. Sixty percent of the bakery staff reported serving food-allergic customers at least once a month, 24% once a week. Eighty four percent of the staff felt able to advise food-allergic consumers regarding a safe product choice. Seventy three 'cow's milk-free' products were sold in 44 bakery shops. Cow's milk could be detected in 43% of the bakery products, 21% contained >3 mg cow's milk protein per serving. Staff in bakery shops felt confident about advising customers with food allergy. However, cow's milk was detectable in almost half of bakery products being sold as 'cow's milk-free'. Every fifth product contained quantities of cow's milk exceeding an amount where approximately 10% of cow's milk-allergic children will show clinical relevant symptoms. © 2015 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  3. DESIGN VERSUS PRODUCT DEVELOPMENT?

    Directory of Open Access Journals (Sweden)

    Edu Grieco Mazzini Junior

    2015-03-01

    Full Text Available Design or product development? The questioning in relation to the employment of such terminology dates back to possible misconceptions regarding interpretation and approach them. Therefore, it can be stated that there are differences between these two terms? In this context, we highlight two views concerning the origin of the design. The first character creative and based on pre-industrial revolution, based on projective and methodologies directed towards the practice of designing products. And second, where design is understood as an industrial process: the development of new products includes, besides a creative procedure are developed, and symbolic formal solutions for products, but also a technical procedure based on the definition of the requirements concerning the product engineering. Is this the most widely accepted interpretation? theoretical studies were conducted from interpretations of the concept of the design proposed by the International Council of Societies of Industrial Design – ICSDI (2012, and for the characterization of the process of product development, we sought to develop an analogy between these two terminologies and can be proved that the use of one of terminology will not cause deviations of interpretation, since both deal with the life cycle of the product. The main results obtained until now the definition of design proposed by the ICSID where it is characterized as a creative activity focused on the complete life cycle of products is the more approaches of the concept of product development.

  4. Ecology of benthic production during southwest monsoon in an estuarine complex of Goa

    Digital Repository Service at National Institute of Oceanography (India)

    Parulekar, A.H.; Dwivedi, S.N.

    Qualitative and quantitative differences in the spatial temporal distribution and production of benthic macrofauna in pre- and post-monsoon were observed and the differences are discussed in relation to the environmental factors The fauna...

  5. Ultrasound assisted biogas production from co-digestion of wastewater sludges and agricultural wastes: Comparison with microwave pre-treatment.

    Science.gov (United States)

    Aylin Alagöz, B; Yenigün, Orhan; Erdinçler, Ayşen

    2018-01-01

    This study investigates the effect of ultrasonication and microwave sludge disintegration/pre-treatment techniques on the anaerobic co-digestion efficiency of wastewater sludges with olive and grape pomaces. The effects of both co-digestion and sludge pre-treatment techniques were evaluated in terms of the organic removal efficiency and the biogas production. The "co-digestion" of wastewater sludge with both types of pomaces was revealed to be a much more efficient way for the biogas production compared to the single (mono) sludge digestion. The ultrasonication and microwave pre-treatments applied to the sludge samples caused to a further increase in biogas and methane yields. Based on applied specific energies, ultrasonication pre-treatment was found much more effective than microwave irradiation. The specific energy applied in microwave pre-treatment (87,000kj/kgTS) was almost 9 times higher than that of used in ultrasonication (10,000kj/kgTS), resulting only 10-15% increases in biogas/methane yield. Co-digestion of winery and olive industry residues with pre-treated wastewater sludges appears to be a suitable technique for waste management and energy production. Copyright © 2017 Elsevier B.V. All rights reserved.

  6. Audio production principles practical studio applications

    CERN Document Server

    Elmosnino, Stephane

    2018-01-01

    A new and fully practical guide to all of the key topics in audio production, this book covers the entire workflow from pre-production, to recording all kinds of instruments, to mixing theories and tools, and finally to mastering.

  7. Dynamics of production and forage utilization on elephant grass pastures managed with different post-grazing heights

    Directory of Open Access Journals (Sweden)

    Braulio Maia de Lana Sousa

    2012-08-01

    Full Text Available This study was conducted to evaluate the daily production of forage and its morphological components, as well as the potential of forage utilization in pastures of Pennisetum purpureum cv. Napier managed with three post-grazing heights (30, 50 and 70 cm. Two experiments were carried out: one from February to May 2009 and another from December 2009 to May 2010, characterizing months of summer and fall. The experimental design was of completely randomized blocks with three replicates. The grazing was performed by crossbred heifers of approximately 270 kg body weight, when the sward intercepted 95% of the incoming light. In both experiments, the pastures managed with post-grazing height of 30 cm, in the summer months (December to March, presented lower daily production of leaves and stems, as well as less daily leaf senescence, which resulted in lower daily forage production and accumulation in comparison with those managed at 70 and 50 cm. In the period from February to March 2009 (experiment 1 and December 2009 to March 2010 (experiment 2, pastures presented greater daily production of leaves and forage, greater daily forage accumulation and more daily leaf senescence in relation to the months of April and May 2009 and 2010. On the other hand, the daily production of stems was higher in the fall, in comparison with the summer. Therefore, elevation in the post-grazing height, especially in the summer, increases the regrowth vigor of elephant grass cv. Napier.

  8. Impact of product development efforts on product introduction and product customization abilities

    DEFF Research Database (Denmark)

    Chaudhuri, Atanu; Dawar, Saloni

    2014-01-01

    This paper investigates the impact of efforts in new product development-manufacturing integration (NPDMI) on new product introduction (NPI) and product customization (PC) abilities and the moderating effects of product design complexity and importance of new product development order winners...... (NPIOW) on the above relationships. The results from the data on 136 Indian manufacturing plants show that NPDMI, product design complexity and NPIOW all have significant positive impact on NPI and PC abilities. Importance of NPIOW has a positive moderating effect on the relationship between NPDMI and PC...... ability change but product design complexity demonstrate no such effect on the above relationships....

  9. The GPM Ground Validation Program: Pre to Post-Launch

    Science.gov (United States)

    Petersen, W. A.

    2014-12-01

    NASA GPM Ground Validation (GV) activities have transitioned from the pre to post-launch era. Prior to launch direct validation networks and associated partner institutions were identified world-wide, covering a plethora of precipitation regimes. In the U.S. direct GV efforts focused on use of new operational products such as the NOAA Multi-Radar Multi-Sensor suite (MRMS) for TRMM validation and GPM radiometer algorithm database development. In the post-launch, MRMS products including precipitation rate, types and data quality are being routinely generated to facilitate statistical GV of instantaneous and merged GPM products. To assess precipitation column impacts on product uncertainties, range-gate to pixel-level validation of both Dual-Frequency Precipitation Radar (DPR) and GPM microwave imager data are performed using GPM Validation Network (VN) ground radar and satellite data processing software. VN software ingests quality-controlled volumetric radar datasets and geo-matches those data to coincident DPR and radiometer level-II data. When combined MRMS and VN datasets enable more comprehensive interpretation of ground-satellite estimation uncertainties. To support physical validation efforts eight (one) field campaigns have been conducted in the pre (post) launch era. The campaigns span regimes from northern latitude cold-season snow to warm tropical rain. Most recently the Integrated Precipitation and Hydrology Experiment (IPHEx) took place in the mountains of North Carolina and involved combined airborne and ground-based measurements of orographic precipitation and hydrologic processes underneath the GPM Core satellite. One more U.S. GV field campaign (OLYMPEX) is planned for late 2015 and will address cold-season precipitation estimation, process and hydrology in the orographic and oceanic domains of western Washington State. Finally, continuous direct and physical validation measurements are also being conducted at the NASA Wallops Flight Facility multi

  10. Production of pre-basic potato seed by polyvinyl chloride PVC: articulate gutters hydroponic system

    Directory of Open Access Journals (Sweden)

    Jonny Everson Scherwinski-Pereira

    2009-10-01

    Full Text Available The development of more efficient and productive systems for pre-basic seed potato production would improve the quality of the propagative material used by the potato growers, directly affecting the crop yields. A two-year experiment was carried out to evaluate the potato pre-basic seed production by two types of hydroponic systems (fibrocement tiles and articulated PVC gutters, two cultivars (`Baronesa` and `Eliza` and two types of propagative material (plants coming from in vitro culture and minitubers. The PVC gutters system was highly efficient. When using minitubers, this system reached multiplication rates up to 74 tubers per plant. Minitubers were more productive than in vitro plants, independent of cultivar and hydroponic system utilized.Um experimento realizado por dois anos consecutivos avaliou a produção de sementes pré-básicas de batata por meio de sistemas de cultivo hidropônico. O trabalho testou a combinação de dois sistemas de cultivo (telha de fibrocimento e calhas de PVC articuladas, duas cultivares (Baronesa e Eliza e dois tipos de material propagativo (plântulas oriundas do cultivo in vitro e minitubérculos. O sistema de calhas de PVC foi altamente eficiente. Quando foi utilizado minitubérculos, este sistema alcançou taxas de multiplicação de até 74 tubérculos por planta. De modo geral, o uso de minitubérculos como material propagativo apresentou os melhores resultados de produtividade quando comparada ao material in vitro, independentemente da cultivar e sistemas hidropônicos utilizados.

  11. Dairy product consumption is associated with pre-diabetes and newly diagnosed type 2 diabetes in the Lifelines Cohort Study.

    Science.gov (United States)

    Brouwer-Brolsma, Elske M; Sluik, Diewertje; Singh-Povel, Cecile M; Feskens, Edith J M

    2018-02-01

    Previous studies show associations between dairy product consumption and type 2 diabetes, but only a few studies conducted detailed analyses for a variety of dairy subgroups. Therefore, we examined cross-sectional associations of a broad variety of dairy subgroups with pre-diabetes and newly diagnosed type 2 diabetes (ND-T2DM) among Dutch adults. In total, 112 086 adults without diabetes completed a semi-quantitative FFQ and donated blood. Pre-diabetes was defined as fasting plasma glucose (FPG) between 5·6 and 6·9 mmol/l or HbA1c% of 5·7-6·4 %. ND-T2DM was defined as FPG ≥7·0 mmol/l or HbA1c ≥6·5 %. Logistic regression analyses were conducted by 100 g or serving increase and dairy tertiles (T1ref), while adjusting for demographic, lifestyle and dietary covariates. Median dairy product intake was 324 (interquartile range 227) g/d; 25 549 (23 %) participants had pre-diabetes; and 1305 (1 %) had ND-T2DM. After full adjustment, inverse associations were observed of skimmed dairy (OR100 g 0·98; 95 % CI 0·97, 1·00), fermented dairy (OR100 g 0·98; 95 % CI 0·97, 0·99) and buttermilk (OR150 g 0·97; 95 % CI 0·94, 1·00) with pre-diabetes. Positive associations were observed for full-fat dairy (OR100 g 1·003; 95 % CI 1·01, 1·06), non-fermented dairy products (OR100 g 1·01; 95 % CI 1·00, 1·02) and custard (ORserving/150 g 1·13; 95 % CI 1·03, 1·24) with pre-diabetes. Moreover, full-fat dairy products (ORT3 1·16; 95 % CI 0·99, 1·35), non-fermented dairy products (OR100 g 1·05; 95 % CI 1·01, 1·09) and milk (ORserving/150 g 1·08; 95 % CI 1·02, 1·15) were positively associated with ND-T2DM. In conclusion, our data showed inverse associations of skimmed and fermented dairy products with pre-diabetes. Positive associations were observed for full-fat and non-fermented dairy products with pre-diabetes and ND-T2DM.

  12. Radiation processing of food and allied products

    International Nuclear Information System (INIS)

    Sharma, Arun

    2009-01-01

    Assuring adequate food security to citizens of the country requires deployment of strategies for augmenting agricultural production while reducing post-harvest losses. Appropriate post-harvest processing, handling, storage and distribution practices are as important as the efforts to increase productivity for sustained food security, food safety and international trade in agricultural commodities. Nuclear energy has played a significant role both in the improvement of crop productivity, as well as, in the preservation and hygienization of agricultural produce

  13. Pre-fractionated Microbial Samples – The Second Generation Natural Products Library at Wyeth

    Directory of Open Access Journals (Sweden)

    Melissa M. Wagenaar

    2008-06-01

    Full Text Available From the beginning of the antibiotic era in the 1940s to the present, Wyeth has sustained an active research program in the area of natural products discovery. This program has continually evolved through the years in order to best align with the “current” drug discovery paradigm in the pharmaceutical industry. The introduction of highthroughput screening and the miniaturization of assays have created a need to optimize natural product samples to better suit these new technologies. Furthermore, natural product programs are faced with an ever shortening time period from hit detection to lead characterization. To address these issues, Wyeth has created a pre-fractionated natural products library using reversed-phase HPLC to complement their existing library of crude extracts. The details of the pre-fractionated library and a cost-benefit analysis will be presented in this review.

  14. Reduction of verotoxigenic Escherichia coli in production of fermented sausages.

    Science.gov (United States)

    Holck, Askild L; Axelsson, Lars; Rode, Tone Mari; Høy, Martin; Måge, Ingrid; Alvseike, Ole; L'abée-Lund, Trine M; Omer, Mohamed K; Granum, Per Einar; Heir, Even

    2011-11-01

    After a number of foodborne outbreaks of verotoxigenic Escherichia coli involving fermented sausages, some countries have imposed regulations on sausage production. For example, the US Food Safety and Inspection Service requires a 5 log(10) reduction of E. coli in fermented products. Such regulations have led to a number of studies on the inactivation of E. coli in fermented sausages by changing processing and post-processing conditions. Several factors influence the survival of E. coli such as pre-treatment of the meat, amount of NaCl, nitrite and lactic acid, water activity, pH, choice of starter cultures and addition of antimicrobial compounds. Also process variables like fermentation temperature and storage time play important roles. Though a large variety of different production processes of sausages exist, generally the reduction of E. coli caused by production is in the range 1-2 log(10). In many cases this may not be enough to ensure microbial food safety. By optimising ingredients and process parameters it is possible to increase E. coli reduction to some extent, but in some cases still other post process treatments may be required. Such treatments may be storage at ambient temperatures, specific heat treatments, high pressure processing or irradiation. HACCP analyses have identified the quality of the raw materials, low temperature in the batter when preparing the sausages and a rapid pH drop during fermentation as critical control points in sausage production. This review summarises the literature on the reduction verotoxigenic E. coli in production of fermented sausages. Copyright © 2011 Elsevier Ltd. All rights reserved.

  15. Students' Demand for Smartphones: Structural Relationships of Product Features, Brand Name, Product Price and Social Infuence

    Science.gov (United States)

    Suki, Norazah Mohd

    2013-01-01

    Purpose: The study aims to examine structural relationships of product features, brand name, product price and social influence with demand for Smartphones among Malaysian students'. Design/methodology/approach: Data collected from 320 valid pre-screened university students studying at the pubic higher learning institution in Federal Territory of…

  16. Enhanced biogas production from anaerobic co-digestion of pig slurry and horse manure with mechanical pre-treatment.

    Science.gov (United States)

    Lopes, Madalena; Baptista, Patrícia; Duarte, Elizabeth; Moreira, António L N

    2018-01-02

    Enhanced biogas production from anaerobic co-digestion of pig slurry and horse manure with mechanical pre-treatment. In this study, co-digestion of horse manure and pig slurry was investigated in a continuously stirred tank reactor, with a mechanical pre-treatment. Experiments were conducted at 37°C, with hydraulic retention times of 23 days and increasing shares of horse manure, corresponding to different horse manure to pig slurry ratios (HM:PS) equal to 0:100, 10:90, 13:87 and 20:80, in terms of percentage of inlet volatile solids (%VS inlet). The results show that the best synergetic effect between the microbial consortia of pig slurry and the high Carbon to Nitrogen ratio (C/N) of horse manure is obtained for the mixture of 20:80%VS inlet, yielding the highest specific methane production (SMP = 142.6 L kg TCOD -1 ) and the highest soluble chemical oxygen demand (SCOD) reduction (68.5%), due to the high volatile dissolved solids content and soluble chemical oxygen demand to total chemical oxygen demand ratio (SCOD/TCOD). Thus, co-digestion of horse manure and pig slurry is shown to be a promising approach for biogas production and as a waste treatment solution. Furthermore, the analysis provides a methodology for the pre-treatment of these substrates and to investigate into the best combination for improved biogas production.

  17. Product and labour market regulations, production prices, wages and productivity

    NARCIS (Netherlands)

    Cette, G.; Lopez, J.; Mairesse, J.

    2015-01-01

    This study is an attempt to evaluate the effects of product and labour market regulations on industry productivity through their various impacts on changes in production prices and wages. In a first stage, the estimation of a regression equation on an industry*country panel, with controls for

  18. Training verb argument structure production in agrammatic aphasia: Behavioral and neural recovery patterns

    Science.gov (United States)

    Thompson, Cynthia K.; Riley, Ellyn A.; den Ouden, Dirk-Bart; Meltzer-Asscher, Aya; Lukic, Sladjana

    2013-01-01

    Introduction Neuroimaging and lesion studies indicate a left hemisphere network for verb and verb argument structure processing, involving both frontal and temporoparietal brain regions. Although their verb comprehension is generally unimpaired, it is well known that individuals with agrammatic aphasia often present with verb production deficits, characterized by an argument structure complexity hierarchy, indicating faulty access to argument structure representations for production and integration into syntactic contexts. Recovery of verb processing in agrammatism, however, has received little attention and no studies have examined the neural mechanisms associated with improved verb and argument structure processing. In the present study we trained agrammatic individuals on verbs with complex argument structure in sentence contexts and examined generalization to verbs with less complex argument structure. The neural substrates of improved verb production were examined using functional magnetic resonance imaging (fMRI). Methods Eight individuals with chronic agrammatic aphasia participated in the study (four experimental and four control participants). Production of three-argument verbs in active sentences was trained using a sentence generation task emphasizing the verb’s argument structure and the thematic roles of sentential noun phrases. Before and after training, production of trained and untrained verbs was tested in naming and sentence production and fMRI scans were obtained, using an action naming task. Results Significant pre- to post-training improvement in trained and untrained (one- and two-argument) verbs was found for treated, but not control, participants, with between-group differences found for verb naming, production of verbs in sentences, and production of argument structure. fMRI activation derived from post-treatment compared to pre-treatment scans revealed upregulation in cortical regions implicated for verb and argument structure processing

  19. Use of basic and specific pre-treatments for the biogas production. Revision and analysis

    International Nuclear Information System (INIS)

    Martínez Hernández, Carlos M.; García López, Yaser

    2016-01-01

    Keeping in mind the importance that has today the use of national and international biogas plants, which use as raw material animal manure; as well as agricultural and agroindustrial residuals for the energy production and biofertilizers, minimizing the aspects of environmental contamination. This work is presented in three parts, in those which: firstly the technologies and the methods are described to apply the basic and special pre-treatments to the different biomass in order to obtain their maximum potential of methane. A second part where it is approached the particularities to do that. Finally, a third part where their possible use is analyzed in the Cuban case. As a result of the same one, the state of the art is shown in the use of basic and special pre-treatments, with the objective of to potentialize the increase of the methane production in agricultural or animal biomasses. (author)

  20. Electrical Qualification of the Pre-production of Analogue Opto-Hybrid Circuits for the CMS Tracker Inner Barrel and Inner Disks.

    CERN Document Server

    Brunetti, Maria Teresa; Postolache, Vasile; Ricci, Daniel

    2003-01-01

    A pre-production of 50 analogue opto-hybrid (AOH) circuits to be used in the front-end electronics of the CMS tracker was extensively tested before the incoming start of the massive production. A total of 4000 AOHs are required for the tracker inner barrel (TIB) and inner disk (TID) construction. The electrical response of the TIB/TID AOH pre-production was tested at 25°C both for the static and dynamic behavior. A subset of five AOHs was cooled and tested at -10°C and -15°C. A passive thermal cycle test from -20°C to 25°C was done on a sample of 22 pre-production AOHs, including the previous subset, to measure the mechanical response at possible variations of the nominal tracker temperature of -10°C. Four AOHs from the subset were also kept at -15°C for 20 hours in order to check the long-term stability of the response. The measurements were obtained with the automatic test equip ment (ATE) built for the fast qualification during the massive AOH production and with a custom setup dedicat...

  1. Quality estimation methods used in product life cycle

    OpenAIRE

    M. Dudek-Burlikowska; D. Szewieczek

    2007-01-01

    Purpose: A new approach to quality control in production company with usage of quality research methods has been presented.Design/methodology/approach: The possibility of usage of quality research methods are connected with continuous quality improvement of pre-production, production and after-production spheres of organization. Interdependence of the quality research methods and product life cycle has been taken into account.Findings: At the present time the enterprises should integrate qua...

  2. Effectiveness of Focus-on-Forms Instruction: Different Outcomes on Constrained- and Free-Production Tasks?

    Directory of Open Access Journals (Sweden)

    Giselle Corbeil

    2005-06-01

    Full Text Available Abstract The purpose of this study is to investigate how focus-on-forms instruction in second language teaching affects attention to forms in two different types of task: constrained and free production. These two different types of task were administered to 87 university students enrolled in a first-year French as a second language course before and after instruction on qualifying adjective agreement. Comparisons were made between learning-gain differences from pre- to post-tests for both tasks. Significant differences between pre- and post-test scores were found for both tasks. Although the difference between the two tasks was not significant, the learning-gain difference was somewhat higher for the constrained-production task than for the free-production task. When the total number of adjectives used in the compositions was broken down into colour adjectives and non-colour adjectives, no significant learning gains were observed between the two categories, although the learning gains for the non-colour adjectives was twice as high as for the colour adjectives. Possible explanations for these results are discussed.

  3. From Product Models to Product State Models

    DEFF Research Database (Denmark)

    Larsen, Michael Holm

    1999-01-01

    A well-known technology designed to handle product data is Product Models. Product Models are in their current form not able to handle all types of product state information. Hence, the concept of a Product State Model (PSM) is proposed. The PSM and in particular how to model a PSM is the Research...

  4. 17 CFR 229.1204 - (Item 1204) Oil and gas production, production prices and production costs.

    Science.gov (United States)

    2010-04-01

    ... production, production prices and production costs. 229.1204 Section 229.1204 Commodity and Securities... production, production prices and production costs. (a) For each of the last three fiscal years disclose... production cost, not including ad valorem and severance taxes, per unit of production. Instruction 1 to Item...

  5. An Explanatory Study of Lean Practices in Job Shop Production/ Special Job Production/ Discrete Production/ Batch Shop Production Industries

    OpenAIRE

    Lavlesh Kumar Sharma; Ravindra Mohan Saxena

    2014-01-01

    In this paper, the study explores the benefits and advantages of Lean Practices or Lean Thinking in Job shop production/ Special job production/ Discrete production/ Batch shop production industries. The Lean Practices have been applied more compatible in Job shop production than in the continuous/ mass production because of several barriers and hurdles in the industrial context that influence the whole processes again and again, this happens due to the lack of knowledge about...

  6. HIGHLY EFFECTIVE CHEMICAL MODIFIERS FOR PRODUCTION OF CONCRETES WITH PRE-SET PROPERTIES

    Directory of Open Access Journals (Sweden)

    Tkach Evgeniya Vladimirovna

    2012-10-01

    Full Text Available The paper demonstrates the application of industrial by-products and recycled materials. Waterproofing admixtures improve the structure and the properties of the cement stone. Development and preparation of highly effective waterproofing modifiers of durable effect, as well as development of the process procedure parameters, including mixing, activation, heat treatment, etc. are to be implemented. The composition of waterproofing modifiers is to be fine-tuned to synergize the behaviour of various ingredients of cement systems to assure the substantial improvement of their strength, freeze- and corrosion resistance. Multi-functional waterproofing admixtures were used to produce highly effective modified concretes. The key idea of the new method of modifying cement-based building materials is that the waterproofing admixture concentration is to exceed 10% of the weight of the binding agent within the per-unit weight of the cement stone, given that its strength does not deteriorate. GKM-type modifier coupled with organo-mineral waterproofing admixture concentration agent GT-M may be recommended for mass use in the manufacturing of hydraulic concrete and reinforced concrete products. Overview of their practical implementation has proven that waterproofing modifier GKM-S, if coupled with waterproofing admixture concentration agent GT-M, improves the corrosion control inside the cement stone and makes it possible to manufacture durable concrete and reinforced concrete products that demonstrate pre-set physical and processing behaviour. Comprehensive concrete modification by modifier GKM-S and waterproofing admixture concentration agent GT-M may be regarded as one of the most ambitious methods of production of highly effective waterproof concretes.

  7. Primary production of tropical marine ecosystems

    Digital Repository Service at National Institute of Oceanography (India)

    Bhattathiri, P.M.A.

    Among tropical marine ecosystems estuaries are one of the highly productive areas and act as a nursery to large number of organisms. The primary production in most of the estuaries is less during the monsoon period. Post-monsoon period shows...

  8. Production monitoring system for understanding product robustness

    DEFF Research Database (Denmark)

    Boorla, Srinivasa Murthy; Howard, Thomas J.

    2016-01-01

    study is used to demonstrate how the monitoring system can be used to efficiently guide corrective action to improve product performance. It is claimed that the monitoring system can be used to dramatically cut the time taken to identify, planand execute corrective action related to typical quality......In the current quality paradigm, the performance of a product is kept within specification by ensuring that its parts are within specification. Product performance is then validated after final assembly. However, this does not control how robust the product performance is, i.e. how much...... it will vary between the specification limits. In this paper, a model for predicting product performance is proposed, taking into account design, assembly and process parameters live from production. This empowers production to maintain final product performance, instead of part quality. The PRECI‐IN case...

  9. Creativity, Scientific Practice, and Knowledge Production

    Science.gov (United States)

    Fryer, Marilyn

    2010-01-01

    In this interesting article, Hisham Ghassib (2010) describes the transformation of science from its craft status in a pre-modern era to the major knowledge industry it is today. He then compares the production of scientific knowledge with industrial production, but makes the important distinction between the process of developing scientific…

  10. Physically based modelling and optimal operation for product drying during post-harvest processing.

    NARCIS (Netherlands)

    Boxtel, van A.J.B.; Lukasse, L.; Farkas, I.; Rendik, Z.

    1996-01-01

    The development of new procedures for crop production and post-harvest processing requires models. Models based on physical backgrounds are most useful for this purpose because of their extrapolation potential. An optimal procedure is developed for alfalfa drying using a physical model. The model

  11. Reproductive and Productive Performance of Iraqi Buffaloes as Influenced by Pre-Mating and Pre-Calving Concentrate Supplementation

    Directory of Open Access Journals (Sweden)

    Talal Anwer Abdulkareem*, Sawsan Ali Al-Sharifi, Sajeda Mahdi Eidan and R.G. Sasser1

    2012-06-01

    Full Text Available The objective of the present study was to investigate the influence of pre-mating and pre-calving concentrate supplementation of Iraqi buffaloes on some of the reproductive (estrus, mating, pregnancy and calving rates and productive (daily milk yield and calves birth weight traits. This study was carried out in 4 Iraqi South-central governorates using 596 pre-mating and 628 pregnant buffaloes (during the last two months of gestation. Pre-mating buffaloes were divided randomly into 496 concentrate-supplemented buffaloes (Flushing and 100 control ones. Additionally, pregnant buffaloes were also divided into 528 concentrate- supplemented buffaloes (Steaming up and 100 controls. Each buffalo within the flushing and steaming up groups were fed daily on 7 Kg of concentrate diet (13% crude protein and 1.70 Mcal of net energy for 60 days. The control buffaloes were nourished only on low-quality roughages of the area and wheat bran. Higher estrus (+15%, P<0.01, pregnancy (+23.8%, P<0.05 and calving rates (+30.8%, P<0.01 were observed in concentrate-supplemented buffaloes as compared with controls. An obvious increase in (P<0.05 calving rate (+14.7%, daily milk yield (+44.8% and calf birth weight (+25.6% were noted in steaming up buffaloes in comparison with control buffaloes. Results indicated that improvement in feeding schedule of Iraqi buffaloes during pre-mating and late gestation periods enhanced the reproductive performance and increased milk production of subsequent lactation and calf birth weight. These improvements increased owner income ($174=209,000 Iraqi dinar /buffalo from the sale of meat and milk.

  12. Quality control on pre-serial Bridgman production of PbWO{sub 4} scintillating crystals by means of photoelasticity

    Energy Technology Data Exchange (ETDEWEB)

    Rinaldi, D., E-mail: d.rinaldi@univpm.i [Dipartimento di Fisica e Ingegneria dei Materiali e del Territorio, Universita Politecnica delle Marche, via Brecce Bianche, 60131 Ancona (Italy); INFN section of Perugia (Italy); Ciriaco, A. [Dipartimento di Fisica e Ingegneria dei Materiali e del Territorio, Universita' Politecnica delle Marche, via Brecce Bianche, 60131 Ancona (Italy); Lebeau, M. [CERN PH department, 1211 Geneva 23 (Switzerland); Paone, N. [Dipartimento di Meccanica, Universita' Politecnica delle Marche, via Brecce Bianche, 60131 Ancona (Italy)

    2010-04-11

    Residual internal stresses in PbWO{sub 4} (PWO) scintillating crystals grown by Bridgman method have been systematically studied. Residual stresses induced during growth play an important role in production yield. Cracking probability during mechanical processing as well as stable mechanical properties in finished crystal are closely related to internal stress levels. A regular production of good-quality crystals requires a fast and easy feed-back on growth parameters. Samples from a pre-serial production were analyzed in order to give the producer a quality feed-back for process optimization. By means of photoelasticity, we measured residual stress distribution in several sections along the growth axis and for typical positions in every section. The stress analysis revealed defects occurring during the crystallization process, attributed to dislocations, lattice disorientation and poly-crystallinity. This work had been prompted by the need for quality monitoring of a pre-serial production of PWO for the CMS experiment at CERN's LHC. Mapping stress levels inside the ingot volume and proposing a synthetic parameter to be used as a quality indicator, the resulting analysis should contribute to parameter optimization and improve the growth performance. The proposed method may be useful in conventional crystal production.

  13. Life Cycle Thinking and Integrated Product Deliveries in renovation projects: Extending the concept of Integrated Product Deliveries with Product Service Systems

    DEFF Research Database (Denmark)

    Schipull Kauschen, Jan

    2012-01-01

    extension to the concept of IPDs discussed. Due to extended product responsibility, the concept of PSSs will offer new possibilities of planning and pre-defining life cycles of IPDs more precisely than for regular building components. Reducing or eliminating point-of-sales will induce producers to optimize...... on renovation projects from Denmark, using different forms of IPDs for façade renovation and discusses the different stakeholder’s perspectives on life cycle thinking and their interests and values regarding sustainable building. Furthermore is the concept of Product Service Systems (PSS) as a valuable...

  14. Effects of ultrasonic and thermo-chemical pre-treatments on methane production from fat, oil and grease (FOG) and synthetic kitchen waste (KW) in anaerobic co-digestion.

    Science.gov (United States)

    Li, Chenxi; Champagne, Pascale; Anderson, Bruce C

    2013-02-01

    The effects of ultrasonic and thermo-chemical pre-treatments on the methane production potential of anaerobic co-digestion with synthetic kitchen waste (KW) or fat, oil and grease (FOG) were investigated. Non-linear regressions were fitted to accurately assess and compare the methane production from co-digestion under the various pre-treatment conditions and to achieve representative simulations and predictions. Ultrasonic pre-treatment was not found to improve methane production effectively from either FOG co-digestion or KW co-digestions. Thermo-chemical pre-treatment could increase methane production yields from both FOG and KW co-digestions. COD solubilization was found to effectively represent the effects of pre-treatment. A comprehensive evaluation indicated that the thermo-chemical pre-treatments of pH=10, 55°C and pH=8, 55°C provided the best conditions to increase methane production from FOG and KW co-digestions, respectively. The most effective enhancement of biogas production (288±0.85mLCH(4)/g TVS) was achieved from thermo-chemically pre-treated FOG co-digestion, which was 9.9±1.5% higher than FOG co-digestion without thermo-chemical pre-treatment. Copyright © 2012 Elsevier Ltd. All rights reserved.

  15. Anaerobic co-digestion of municipal organic wastes and pre-treatment to enhance biogas production from waste.

    Science.gov (United States)

    Li, Chenxi; Champagne, Pascale; Anderson, Bruce C

    2014-01-01

    Co-digestion and pre-treatment have been recognized as effective, low-cost and commercially viable approaches to reduce anaerobic digestion process limitations and improve biogas yields. In our previous batch-scale study, fat, oil, and grease (FOG) was investigated as a suitable potential co-substrate, and thermo-chemical pre-treatment (TCPT) at pH = 10 and 55 °C improved CH4 production from FOG co-digestions. In this project, co-digestions with FOG were studied in bench-scale two-stage thermophilic semi-continuous flow co-digesters with suitable TCPT (pH = 10, 55 °C). Overall, a 25.14 ± 2.14 L/d (70.2 ± 1.4% CH4) biogas production was obtained, which was higher than in the two-stage system without pre-treatment. The results could provide valuable fundamental information to support full-scale investigations of anaerobic co-digestion of municipal organic wastes.

  16. Regulation of natural health products in Canada.

    Science.gov (United States)

    Smith, Alysyn; Jogalekar, Sumedha; Gibson, Adam

    2014-12-02

    In Canada, all natural health products (NHPs) are regulated by Health Canada (HC) under the Food and Drugs Act and the Natural Health Product Regulations. All authorized products undergo pre-market assessment for safety, efficacy and quality and the degree of pre-market oversight varies depending on the risk of the product. In Canada, over 70,000 products have been authorized for sale and over 2000 sites have been licensed to produce NHPs. In the management of NHPs on the Canadian market, HC employs a number of active and collaborative methods to address the most common issues such as contamination, adulteration and deceptive or misleading advertising practices. HC is currently evolving its approaches to NHPs to recognize them as part of the larger group of health products available without a prescription. As such, the regulatory responsibility for all over-the-counter (OTC) drugs, including non-prescription drugs and NHPs, has been transferred to a single federal division. As a result of this transition a number of benefits are being realized with respect to government efficiency, clarity for industry, support for new innovations and consolidated government interactions with the Canadian market. Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

  17. Digital cinema: an alternative model for post-apartheid cinematic production and consumption?

    Directory of Open Access Journals (Sweden)

    Astrid Treffry-Goatley

    2011-10-01

    Full Text Available http://dx.doi.org/10.5007/2175-8026.2011n61p315 Patterns of cinematic production and consumption are often symptomatic of wider politico-economic and socio-cultural forces. This is the case in South Africa, where this site of cultural production, like the society as a whole, is marked by severe racial stratification and division. One finds, for example, that as a direct result of apartheid inequality, the majority of the population has been alienated from the mechanisms of cinematic production and consumption. This fragmentation remains one of the greatest challenges to the sustainability and racial transformation of the post-apartheid film industry. In this article I present a critical discussion on the rise of the low-budget, digital film in South Africa. With careful reference to prevailing politico-economic conditions and available state-support measures I analyse the potential of digital technology to revolutionise cinematic production and consumption practices. In analysis, it was found that while cinema has indeed become somewhat more accessible, the production, distribution and exhibition of motion pictures in South Africa remain monopolised, exclusive and inaccessible to the majority. Moreover, it is questionable whether the digitised consumption mechanisms in place penetrate a wide enough market to sustain the movement. Therefore, although this is indeed an exciting movement in the industry, it should not be viewed as an outright replacement of existing technology nor a means for independent filmmakers to make it alone. On the contrary, it is most likely to run parallel to existing entertainment mechanisms and state support will still be required to encourage diversity and encourage sustainability.

  18. A life cycle assessment of non-renewable energy use and greenhouse gas emissions associated with blueberry and raspberry production in northern Italy.

    Science.gov (United States)

    Girgenti, Vincenzo; Peano, Cristiana; Bounous, Michele; Baudino, Claudio

    2013-08-01

    This study examined the emissions produced during the pre-farm, farm and post-farm phases of the production cycle of raspberries and giant American whortleberries (blueberries) cultivated in one of the best-adapted areas in northern Italy. The pre-farm phase included the greenhouse gas emissions from the production of plants in the nursery and the transportation of the plants to the production farms. The farm phase involved the emissions of greenhouse gases from chemical products, the water used for irrigation, the generation of waste, and the consumption of electricity and other energy. The post-farm phase comprised the transportation of the products to the distribution centre (DC) and their storage in the DC. The use phase is not included in the system, nor is transportation from the supermarket to the home of the final consumer, but the disposal of the packaging is nevertheless taken into account. Indeed, the use of traditional plastic materials during both the field phase (nursery and cultivation) and the post-harvesting phase (packaging) produced the greatest estimated impact. Copyright © 2013 Elsevier B.V. All rights reserved.

  19. 78 FR 28643 - Technicolor Creative Services, Post Production Feature Mastering Division, Hollywood, California...

    Science.gov (United States)

    2013-05-15

    ... DEPARTMENT OF LABOR Employment and Training Administration [TA-W-81,335] Technicolor Creative Services, Post Production Feature Mastering Division, Hollywood, California; Notice of Termination of Reconsideration Investigation Pursuant to Section 221 of the Trade Act of 1974, as amended, a reconsideration investigation was initiated in on August ...

  20. Method for alignment of product and production concepts

    DEFF Research Database (Denmark)

    Pedersen, Rasmus; Kvist, Morten; Mortensen, Niels Henrik

    2005-01-01

    The right use of modular product architectures can help companies provide a great variety of customized products at a competitive price level, by reuse of knowledge, components, processes and utilization of economies of scale in many of the activities that are necessary to provide products...... for customers. Modular product architectures often serve as a basis for several products often referred to as product families. One or more product families may constitute a substantial amount of the total product portfolio of a company, and it is, therefore, of the greatest importance that concepts...... and solutions are evaluated thoroughly throughout the design phases because any design fault is likely to propagate to a large part of the business. Developing modular product architectures is therefore also the task of ensuring a fit between the products that can be made on the basis of the architecture...

  1. Near vision correction and work productivity among textile workers

    Directory of Open Access Journals (Sweden)

    Kovin S. Naidoo

    2016-11-01

    Full Text Available Purpose: Uncorrected presbyopia (near vision impairment is prevalent in approximately 517 million people worldwide; this prevalence ranges from 30% to 80% in Africa. Good near vision is needed for a range of tasks; therefore, uncorrected presbyopia can negatively affect the quality of life of individuals, impact families and society, and potentially have negative implications on employment and labour work productivity. This study aimed to determine the impact of near vision correction on the work productivity of clothing factory workers. Methods: We conducted a cross-sectional study and sampled all workers who were aged 40 years and older and who performed near vision tasks (e.g. machinist, cutter, zip sewer, clothing pressers and quality controllers in seven clothing factories. We included workers who were employed for at least 3 months and whose uncorrected near visual acuity could be improved and corrected to better than 6/9 with spectacle correction. Workers were provided with near vision spectacles, and changes in their work productivity were evaluated after 6 months, using the factories’ output records as an indicator for measurement. Results: The final sample comprised 268 individuals, with 56% of African origin (n = 151 and 49% (n = 115 Indian origin. There were mainly females (94% in the sample, and the average age was 48 years (± 5.5 years, range 40–62 years. The overall post-correction mean production score (70.5 [SD ± 19.9] was significantly higher than the overall pre-correction mean production score (67.0 [SD ±20.3] (p < 0.001. The average change in production score was 3.5 (95% confidence interval [CI] 2.7–4.3, and the percent difference was 6.4% (95% CI 5.2–7.7. The increase in work productivity was significant for individuals of African (p < 0.001 and Indian origins (p < 0.001 but not for those of mixed race (p = 0.364; n = 2. Post-correction, the production scores of women increased significantly by 6.6% (95% CI 5.3

  2. Product Structure, the Heart of Product Definition

    Science.gov (United States)

    DeHoog, C., Jr.

    1999-01-01

    This paper describes the LMMSS Product Definition System (PDS) philosophy and approach were the use of each item parts document or software can be traced to a specific end item (EI) serial/tail number of the product. It explains why a part-oriented approach to data organization and configuration management is required. The definition of part-oriented is that all appropriate product definition data products will be collected. Referenced and managed by their linkage/relationship to parts/items, The paper will touch upon how LMMSS store/controls product definition information under each project's top product designator in a two tiered approach. One tier for each product end item and another tier which contain/controls listings of drawings, documents. Specifications and standards that are required for hardware item definition.

  3. Effects of product\\'s warranty on customers\\' preferences: empirical findings on reverse logistics models

    Directory of Open Access Journals (Sweden)

    Arsalan Najmi

    2014-09-01

    Full Text Available Background: IT products are now becoming the part of every one's life. Since Pakistan didn't manufacture IT products, so the customers had to purchase the products that are available in the markets. During such purchase, customers not only gave preference to brand or price or both but they also consider its warranty so that they are secured with the post purchase risks. Methods: This study was aimed to identify the impact of the warranty on customers' preferences towards brand and price. A conceptual framework was made on the basis of available literature and then data was collected. It was collected from 298 respondents through survey questionnaire and after applying Factor Analysis, One Way MANOVA was applied on the factors. Results and conclusions: The study found that the product's warranty has a significant impact on preferences towards brand, concern for price and price intentions whereas the impact on willingness to pay was found insignificant. The results conclude that Pakistani customers need a branded IT product on competitive prices, which give more in less along with the warranty so that they can enjoy the same quality of the product for a period of time whereas, they are not willing to pay any additional amount for the product just because of Warranty.

  4. Product-Marketing Innovation, Skills, and Firm Productivity Growth

    DEFF Research Database (Denmark)

    Junge, Martin; Severgnini, Battista; Sørensen, Anders

    2016-01-01

    The role of product and marketing innovation for productivity growth is addressed using survey and register data for the Danish economy. It is hypothesized that product and marketing innovation are complementary inputs and that innovation activities are skill-intensive. It is established...... that product and marketing innovation in skill-intensive firms results in significantly faster productivity growth. Moreover, product and marketing innovation have independent roles in productivity growth, which cannot be attributed to organizational changes. Finally, we apply an instrument variable approach...... for firms, innovation choices to study endogeneity. The results strongly support the idea that product–marketing innovation leads to faster productivity growth in skill-intensive firms....

  5. MANAJEMEN EDITING POST PRODUCTION PROGRAM CURRENT AFFAIR DI TVONE

    Directory of Open Access Journals (Sweden)

    Ridho Azlam Ambo Asse

    2016-11-01

    Full Text Available Management is the art of completing the work through others. In an organization there are various components that are structured and coordinated in the movement toward shared vision and mission. Management is looking for that component to move under coordination, pressure, and problems that hit. Editing management, especially for the current affair type program, has a special purpose. Not just the speed of productivity that is based on the ability of individual editors. This research is done to know the process of stage editor in work. The process of managing files, data management, human resources, tools, facilities, scheduling, until the pattern of editing stage in one of the national media industry. This study concludes that the current affair program management editing system based on the concept of planning, organizing, implementation, supervision, and productivity management is done by Top Down method from top to bottom in the management of currenf affair tvOne editing program. What gets from above during a pre-production meeting of a program. Then coordinate with the supervisor and then delegate down to be implemented according to the agreed plan and in accordance with the duties and functions of both the production team and the editor.   Manajemen merupakan seni menyelesaikan pekerjaan melalui orang lain. Dalam sebuah organisasi terdapat berbagai macam komponen yang terstruktur dan terkordinasi dalam gerakan menuju visi dan misi bersama. Manajemen ialah mencari agar komponen tersebut dapat bergerak dibawah koordinasi, tekanan, dan masalah yang menerpa. Manajemen editing khususnya untuk program berjenis current affair, memiliki tujuan khusus. Tidak sekedar kecepatan produktifitas yang didasarkan pada kemampuan individu editor. Penelitian yang dilakukan ini untuk mengetahui proses tahapan editor dalam bekerja. Proses mengelola file, pengelolaan data, sumber daya manusia, alat, fasilitas, penjadwalan, hingga pola tahapan editing pada salah

  6. Integrating Environmental Decisions into the Product Development Process: Part 1 - The Early Stages

    DEFF Research Database (Denmark)

    Bhamra, T.; Evans, S.; McAloone, Timothy Charles

    1999-01-01

    environmental decisions into their product development process which is very unusual in that ecodesign is significantly different for the pre- and post-specification stages of the design process. This paper explains the findings related to the first phase being the very early stages of the product development...... in the UK, Central Europe and the USA are carrying out Ecodesign. The survey also investigated the successes and failures companies had experienced and the lessons they had learnt along the way. From this survey we identified a number of success factors that enabled companies to successfully integrate...... process prior to the specification being finalised. A second paper, considers the findings from the later phases of the product development process....

  7. Minimum Risk Pesticide: Definition and Product Confirmation

    Science.gov (United States)

    Minimum risk pesticides pose little to no risk to human health or the environment and therefore are not subject to regulation under FIFRA. EPA does not do any pre-market review for such products or labels, but violative products are subject to enforcement.

  8. 75 FR 4693 - New Postal Product

    Science.gov (United States)

    2010-01-29

    ... Post Group exceed six times the rate for the first ounce of a First-Class Mail letter. Id., para. (e... Dominant Products 1000 Market Dominant Product List First-Class Mail Single-Piece Letters/Postcards Bulk Letters/Postcards Flats Parcels Outbound Single-Piece First-Class Mail International Inbound Single-Piece...

  9. Product-Marketing Innovation, Skills and Firm Productivity Growth

    DEFF Research Database (Denmark)

    Junge, Martin; Severgnini, Battista; Sørensen, Anders

    The role of product and marketing innovation for productivity growth is addressed using survey and register data for the Danish economy. It is argued that marketing and product innovation are complementary inputs and that innovation activities are skill-intensive. It is found that product...... and marketing innovation in skill-intensive firms results in significantly faster productivity growth than in unskilled-intensive firms that introduce this combination of innovation activities. More precisely, an increase in the share of educated workers of one percentage point, increases productivity growth...... by around 0.1 percentage point in firms with product and marketing innovation. In addition, it is found that firms that engage in product innovation but not in marketing innovation or the other way around do not demonstrate a growth effect from their innovation activities. It is also found that product...

  10. Production of hydrogen from by-products of food industries by rhodospirillaceae

    Energy Technology Data Exchange (ETDEWEB)

    Reh, U.

    1983-11-01

    The decomposition of organic substances from food-by-products as whey, beet sugar molasses, cane-sugar-molasses and potato-water by the Rhodospirillaceae Rp. capsulata, Rp. acidophila, Rm. vannielii, Rs. rubrum, and Rs. tenue to hydrogen and carbon dioxide were tested. In a pre-cultivation Lactobacillus bulgaricus converted the sugars of the by-products into lactic acid, which is easier in handling. Rs. rubrum was superior in producing hydrogen from this nutrient. It released from whey up to 56% of the substrate hydrogen, from beet sugar molasses 42%, from cane-sugar-molasses 89% and from potato-water 19%. Out-door-researches were made to evaluate the decrease of hydrogen yield under the influence of weather as well as day and night periods compared to the homogeneous conditions of the laboratory. From 200 m/sup 3/ whey, the daily output of a dairy, 4000 m/sup 3/ hydrogen corresponding to an energy equivalent of 1000 l fuel oil could be produced. To achieve this, 130 000 m/sup 2/ have to be covered with batch fermenters. These results show, that there is nearly no hope to decompose food by-products by Rhodospirillaceae in large scale technology, unless a new processing technology using a flow-fermenter and raising the hydrogen production significantly will be found.

  11. 1,25-Dihydroxyvitamin D3 inhibits cytokine production by human blood monocytes at the post-transcriptional level

    DEFF Research Database (Denmark)

    Müller, K; Haahr, P M; Diamant, M

    1992-01-01

    was not caused by impaired production of mRNA. Taken together, the study demonstrates a vitamin D-induced inhibitory effect of LPS-driven monokine production, which is most likely a vitamin D-receptor mediated phenomenon exerted at a post-transcriptional, presecretory level. Impaired monokine production may...... be of importance in 1,25-(OH)2D3-mediated inhibition of lymphocyte functions in vitro.......1,25-Dihydroxyvitamin D3 [1,25-(OH)2D3] inhibits lymphocyte proliferation and production of antibodies and lymphokines such as interleukin (IL)-2 and interferon gamma. These lymphocyte functions are dependent upon cytokines, including IL-1 alpha, IL-1 beta, IL-6 and tumour necrosis factor alpha...

  12. SaferProducts.gov

    Science.gov (United States)

    ... sent to your business before they are posted online. Sign up with the Business Portal to get reports quickly. Get Started Do ... Safe: Watch and Share Report an Unsafe Product Business Sign In Search Recalls/Repairs & Reports Advanced Search ... OF USE | PRIVACY | NO FEAR | OPEN GOVERNMENT ...

  13. An integrated production, inventory and preventive maintenance model for a multi-product production system

    International Nuclear Information System (INIS)

    Liu, Xuejuan; Wang, Wenbin; Peng, Rui

    2015-01-01

    This paper considers a production system that can produce multiple products alternately. Products go through the system in a sequence and a complete run of all products forms a production cycle. An integrated production, inventory and preventive maintenance model is constructed, which is characterized by the delay-time concept. Two different situations are studied based on whether the unqualified products and downtime caused by the failures of the system, set-up and preventive maintenance can be ignored or not. Three cases are considered for each situation, depending on the position of the preventive maintenance epochs: the first case, where preventive maintenance is carried out at the end of each production cycle; the second case, where preventive maintenance is carried out at each set-up time of the products; and the third case, where preventive maintenance is carried out at some set-up times only, since it may not always be optimal to carry out preventive maintenance at the end of the production cycle or at each set-up time. The modeling objectives are to find the optimal number of production cycles per year and the optimal position of preventive maintenance that will maximize the expected profit per unit time. Numerical examples, using real data, are presented to illustrate the model. - Highlights: • We propose an integrated economic production quantity and preventive maintenance model. • The situation that multiple products are produced on the same system alternately is studied. • Two situations are studied based on whether the downtime and the product quality can be ignored or not. • We use enumeration method and analytical method to select the optimal preventive maintenance policy, respectively. • We use the delay-time concept to model the preventive maintenance policy

  14. Sustainable Multi-Product Seafood Production Planning Under Uncertainty

    International Nuclear Information System (INIS)

    Simanjuntak, Ruth; Mawengkang, Herman; Sembiring, Monalisa; Sinaga, Rani; Pakpahan, Endang J

    2013-01-01

    A multi-product fish production planning produces simultaneously multi fish products from several classes of raw resources. The goal in sustainable production planning is to meet customer demand over a fixed time horizon divided into planning periods by optimizing the tradeoff between economic objectives such as production cost, waste processed cost, and customer satisfaction level. The major decisions are production and inventory levels for each product and the number of workforce in each planning period. In this paper we consider the management of small scale traditional business at North Sumatera Province which performs processing fish into several local seafood products. The inherent uncertainty of data (e.g. demand, fish availability), together with the sequential evolution of data over time leads the sustainable production planning problem to a nonlinear mixed-integer stochastic programming model. We use scenario generation based approach and feasible neighborhood search for solving the model.

  15. STATEMENT OF THE OPTIMIZATION PROBLEM OF CARBON PRODUCTS PRODUCTION

    Directory of Open Access Journals (Sweden)

    O. A. Zhuchenko

    2016-08-01

    Full Text Available The paper formulated optimization problem formulation production of carbon products. The analysis of technical and economic parameters that can be used to optimize the production of carbonaceous products had been done by the author. To evaluate the efficiency of the energy-intensive production uses several technical and economic indicators. In particular, the specific cost, productivity, income and profitability of production. Based on a detailed analysis had been formulated optimality criterion that takes into account the technological components of profitability. The components in detail the criteria and the proposed method of calculating non-trivial, one of them - the production cost of each product. When solving the optimization problem of technological modes of production into account constraints on the variables are optimized. Thus, restrictions may be expressed on the number of each product produced. Have been formulated the method of calculating the cost per unit of product. Attention is paid to the quality indices of finished products as an additional constraint in the optimization problem. As a result have been formulated the general problem of optimizing the production of carbon products, which includes the optimality criterion and restrictions.

  16. Biobutanol Production from Hexose and Pentose Sugars

    NARCIS (Netherlands)

    Raganati, F.; Procentese, A.; Olivieri, G.; Salatino, P.; Marzocchella, A.

    2014-01-01

    The Acetone-Butanol-Ethanol (ABE) fermentation is receiving renewed interest as a way to upgrade renewable resources for the production of products with high added value as chemicals and fuels. Main pre-requisites of fermentation feedstocks are abundance and un-competitiveness with food sources and

  17. Effect of warm-smoking on total microbial count of meat products

    Directory of Open Access Journals (Sweden)

    A Javadi

    2007-11-01

    Full Text Available The frankfurters are amongst the most famous and popular sausages in the world and beef and poultry meat are used in Iran for their preparation. The techniques of warm smoking at 42°c for two hours and then hot smoking together with steam cooking at 8°c for one hour are utilized in proportion of this product. In spite of its carcinogenic properties, smoke is used to create color, flavor and odor and to improve the preservative qualities of sausages. In this study, 14 sausage samples were taken from each of the stages of frankfurter production line including pre-smoking, post- warm smoking and post-hot smoking, their total microbial counts (aerobic mesophiles determined and the means of the three stages compared using the ANOVA statistical test. The results indicated that the total microbial count increased significantly (P

  18. PRODUCTIVITY COMPARISON BETWEEN BOER AND KACANG GOAT DAM

    Directory of Open Access Journals (Sweden)

    S. Elieser

    2014-10-01

    Full Text Available A study to evaluate the productivity of Boer and Kacang goats dam was carried out for 2 years atResearch Institute for Goat Production, Sungei Putih-North Sumatera. The materials used were goatsowned by the institute. The parameters observed were total birth and weaning weights of kid, litter size,parity of dam, pre-weaning mortality and kidding interval. The rate of reproduction and productivity ofthe dam were estimated using Amir and Knipscheer methods and were statistically analyzed usingGeneral Linear Model. The results showed that the total birth and weaning weight of Boer goats werehigher (P<0.05 than that of Kacang goats, while litter size of Boer goats were higher (P<0.05 than thatof Kacang goats. The pre-weaning mortality of Boer goat 15.1 ± 6.02% was lower than that ofKacang. The kidding interval of Boer goats was higher (P<0.05 than that of Kacang. Parity of dam hadsignificant effect on all production traits (P<0.05 except for pre-weaning mortality. Dam reproductionrate of Boer (1.81 was higher than that of Kacang (1.78, while productivity of Boer goat (37.12kg/head/year was higher than that of Kacang (18.12. It can be concluded that the reproductivity ofBoer and Kacang goats were similar, however the productivity of Boer goat had better than Kacang.

  19. Aluminum corrosion product release kinetics

    Energy Technology Data Exchange (ETDEWEB)

    Edwards, Matt, E-mail: Matthew.Edwards@cnl.ca; Semmler, Jaleh; Guzonas, Dave; Chen, Hui Qun; Toor, Arshad; Hoendermis, Seanna

    2015-07-15

    Highlights: • Release of Al corrosion product was measured in simulated post-LOCA sump solutions. • Increased boron was found to enhance Al release kinetics at similar pH. • Models of Al release as functions of time, temperature, and pH were developed. - Abstract: The kinetics of aluminum corrosion product release was examined in solutions representative of post-LOCA sump water for both pressurized water and pressurized heavy-water reactors. Coupons of AA 6061 T6 were exposed to solutions in the pH 7–11 range at 40, 60, 90 and 130 °C. Solution samples were analyzed by inductively coupled plasma atomic emission spectroscopy, and coupon samples were analyzed by secondary ion mass spectrometry. The results show a distinct “boron effect” on the release kinetics, expected to be caused by an increase in the solubility of the aluminum corrosion products. New models were developed to describe both sets of data as functions of temperature, time, and pH (where applicable)

  20. Studies on the radiosterilization of medical products

    International Nuclear Information System (INIS)

    Lee, K.S.; Min, B.H.; Chun, K.J.; Kim, K.S.

    1979-01-01

    Most of the microorganisms isolated from the medical products were inactivated by the irradiation of 1.0-1.5 Mrad. However, some microorganisms were inactivated as the factor of 10 8 cells by the irradiation of 2.0-2.3 Mrad. Micrococcus roseus was a radioresistant strain, and on the view point of 10 8 cell number the dose for inactivating the Micrococcus roseus in a liquid and lyophilized condition was 2.3 and 3.5 Mrad, respectively. It has been found that the radiosensitivity of microorganism was influenced differently according to the suspended solution, oxygen, temperature and others. Radiosterlization of vaccine could not be performed due to the degeneration of vaccine. Cotton products were suitable where as disposable plastic set such as PVC product was not much suitable due to the reduction of pH or formation of oxidasable matter. Antibiotics in dry state was suitable where as dextrose solution or saline solution was unsuitable packing sheets (P.E, P.P, PVC) were suitable up to 2.5 Mrad dose. There was no relationships between cell growth rate and dose level in toxicity experiment of the irradiated plastic sets. Micrococcus roseus and Escherichia coli were effectively inactivated by treating heat pre-, post- or simultaneous irradiation. (author)

  1. Framework for product knowledge and product related knowledge which supports product modelling for mass customization

    DEFF Research Database (Denmark)

    Riis, Jesper; Hansen, Benjamin Loer; Hvam, Lars

    2003-01-01

    on experience from product modelling projects in several companies. Among them for example companies manufacturing electronic switchboards, spray dryer systems and air conditioning equipment. The framework is divided into three views: the product knowledge view, the life phase system view and the transformation...... and personalization. The framework for product knowledge and product related knowledge is based on the following theories: axiomatic design, technical systems, theory of domains, theory of structuring, theory of properties and the framework for the content of product and product related models. The framework is built......The article presents a framework for product knowledge and product related knowledge which can be used to support the product modelling process which is needed for developing IT systems. These IT systems are important tools for many companies when they aim at achieving mass customization...

  2. PIGS BREEDING FOR THE PRODUCTION OF TRADITIONAL MEAT PRODUCTS

    Directory of Open Access Journals (Sweden)

    Đuro Senčić

    2014-06-01

    Full Text Available The fertile Slavonia is known for production of several types of cured meats: kulen, kulen sis, sausage, ham and bacon, and other pork products (“krvavica” - blood sausage, “švargl” - a type of brawn where chopped parts of head are stuffed inside the pig’s stomach, “čvarci” - a variant of pork crisps, fat. These products require “mature pigs” of adequate slaughter quality. Production of pigs intended for traditional meat products may take place in different production systems (open, closed, semi-open, “organic”. Each of these systems provides a specific quality of pigs for slaughter, reflecting on the quality of the final product. Production systems can have a significant impact on growth performance and carcass and meat quality of pigs. This effect arises from the interaction between housing conditions, the amount and composition of food and used pig genotype. The choice of a production system depends on local production conditions, pig genotype, consumer demand (market for a given product quality, and other factors. Due to their quality, the traditional Slavonian meat products can become a recognizable Croatian brand in both domestic and international markets. Production of standard quality products requires standard quality of pigs. Therefore this book is focused on such pigs production.

  3. 78 FR 20176 - Credit for Renewable Electricity Production, Refined Coal Production, and Indian Coal Production...

    Science.gov (United States)

    2013-04-03

    ..., Refined Coal Production, and Indian Coal Production, and Publication of Inflation Adjustment Factors and... renewable electricity production, refined coal production, and Indian coal production under section 45... resources, and to 2013 sales of refined coal and Indian coal produced in the United States or a possession...

  4. 77 FR 21835 - Credit for Renewable Electricity Production, Refined Coal Production, and Indian Coal Production...

    Science.gov (United States)

    2012-04-11

    ..., Refined Coal Production, and Indian Coal Production, and Publication of Inflation Adjustment Factors and... electricity production, refined coal production, and Indian coal production under section 45. DATES: The 2012... sales of refined coal and Indian coal produced in the United States or a possession thereof. Inflation...

  5. Myoglobin production in emperor penguins.

    Science.gov (United States)

    Ponganis, P J; Welch, T J; Welch, L S; Stockard, T K

    2010-06-01

    Increased oxygen storage is essential to the diving capacities of marine mammals and seabirds. However, the molecular mechanisms underlying this adaptation are unknown. Myoglobin (Mb) and Mb mRNA concentrations were analyzed in emperor penguin (Aptenodytes forsteri) adults and chicks with spectrophotometric and RNase protection assays to evaluate production of their large Mb-bound O(2) stores. Mean pectoral Mb concentration and Mb mRNA content increased throughout the pre-fledging period and were 15-fold and 3-fold greater, respectively, in adults than in 3.5 month old chicks. Mean Mb concentration in 5.9 month old juveniles was 2.7+/-0.4 g 100 g(-1) muscle (44% that of wild adults), and in adults that had been captive all their lives it was 3.7+/-0.1 g 100 g(-1) muscle. The Mb and Mb mRNA data are consistent with regulation of Mb production at the level of transcription as in other animals. Significant Mb and Mb mRNA production occurred in chicks and young juveniles even without any diving activity. The further increase in adult Mb concentrations appears to require the exercise/hypoxia of diving because Mb concentration in captive, non-diving adults only reached 60% of that of wild adults. The much greater relative increase in Mb concentration than in Mb mRNA content between young chicks and adults suggests that there is not a simple 1:1 relationship between Mb mRNA content and Mb concentration. Nutritional limitation in young chicks and post-transcriptional regulation of Mb concentration may also be involved.

  6. A model for optimizing the production of pharmaceutical products

    Directory of Open Access Journals (Sweden)

    Nevena Gospodinova

    2017-05-01

    Full Text Available The problem associated with the optimal production planning is especially relevant in modern industrial enterprises. The most commonly used optimality criteria in this context are: maximizing the total profit; minimizing the cost per unit of production; maximizing the capacity utilization; minimizing the total production costs. This article aims to explore the possibility for optimizing the production of pharmaceutical products through the construction of a mathematical model that can be viewed in two ways – as a single-product model and a multi-product model. As an optimality criterion it is set the minimization of the cost per unit of production for a given planning period. The author proposes an analytical method for solving the nonlinear optimization problem. An optimal production plan of Tylosin tartrate is found using the single-product model.

  7. Production benefits from pre- and post-lambing anthelmintic treatment of ewes on commercial farms in the southern North Island of New Zealand.

    Science.gov (United States)

    Miller, C M; Ganesh, S; Garland, C B; Leathwick, D M

    2015-07-01

    To measure the magnitude and variability in production responses to anthelmintic treatments administered to adult ewes around lambing. Ewes carrying twin lambs, from sheep and beef farms (eight in Year 1 and six in Year 2) in the Wairarapa region of New Zealand, were enrolled in 14 trials (part of an experiment carried out on one farm in one year). Experiment 1 compared ewes treated 2-4 weeks pre-lambing with a controlled release capsule (CRC) containing abamectin, albendazole, Se and Co, to ewes injected pre-lambing with a long-acting Se plus vitamin B12 product, and to untreated ewes. Experiment 2 included these treatments, plus a CRC administered at pregnancy scanning. Experiment 3 included the same treatments as Experiment 1, plus administration of a CRC containing albendazole, Se and Co, injectable moxidectin or oral derquantel plus abamectin, all administered pre-lambing, or oral derquantel plus abamectin administered 4-6 weeks after lambing. Variables compared were ewe liveweight at weaning and pre-mating, lamb liveweight at weaning, total weight of lamb weaned per ewe and ewe dag score at weaning. Ewes treated with a CRC pre-lambing were heavier than untreated ewes (mean 3.2 kg) at weaning in 12/14 trials, and pre-mating (mean 2.8 kg) in 9/14 trials (pewes the mean difference was 2.8 kg pre-lambing (9/14 trials) and 1.7 kg pre-weaning (6/14 trials). Lambs reared by treated ewes were heavier (mean 1.55 kg) at weaning in 6/14 trials (pewe (p=0.507). Variation in weight of lamb weaned per ewe was largely explained by differences in lamb survival from birth to weaning (p0.65). Treatment of ewes with a CRC at pregnancy scanning was neither better nor worse than a pre-lambing treatment (p=0.065). There was no difference in the response from treatment with either of the two CRC or moxidectin. Treatment with short-acting oral anthelmintics resulted in no consistent benefit. Anthelmintic treatments administered to ewes around lambing resulted in variable responses

  8. New Product Launching Ideas

    Science.gov (United States)

    Kiruthika, E.

    2012-09-01

    Launching a new product can be a tense time for a small or large business. There are those moments when you wonder if all of the work done to develop the product will pay off in revenue, but there are many things are can do to help increase the likelihood of a successful product launch. An open-minded consumer-oriented approach is imperative in todayís diverse global marketplace so a firm can identify and serve its target market, minimize dissatisfaction, and stay ahead of competitors. Final consumers purchase for personal, family, or household use. Finally, the kind of information that the marketing team needs to provide customers in different buying situations. In high-involvement decisions, the marketer needs to provide a good deal of information about the positive consequences of buying. The sales force may need to stress the important attributes of the product, the advantages compared with the competition; and maybe even encourage ìtrialî or ìsamplingî of the product in the hope of securing the sale. The final stage is the post-purchase evaluation of the decision. It is common for customers to experience concerns after making a purchase decision. This arises from a concept that is known as ìcognitive dissonance

  9. Exploring the potential of biobeds for the depuration of pesticide-contaminated wastewaters from the citrus production chain: Laboratory, column and field studies

    International Nuclear Information System (INIS)

    Omirou, M.; Dalias, P.; Costa, C.; Papastefanou, C.; Dados, A.; Ehaliotis, C.; Karpouzas, D.G.

    2012-01-01

    The high wastewater volumes produced during citrus production at pre- and post-harvest level presents serious pesticide point-source pollution for groundwater bodies. Biobeds are used for preventing such point-source pollution occurring at farm level. We explored the potential of biobeds for the depuration of wastewaters produced through the citrus production chain following a lab-to-field experimentation. The dissipation of pesticides used pre- or post-harvest was studied in compost-based biomixtures, soil, and a straw-soil mixture. A biomixture of composted grape seeds and skins (GSS-1) showed the highest dissipation capacity. In subsequent column studies, GSS-1 restricted pesticides leaching even at the highest water load (462 L m −3 ). Ortho-phenylphenol was the most mobile compound. Studies in an on-farm biobed filled with GSS-1 showed that pesticides were fully retained and partially or fully dissipated. Overall biobeds could be a valuable solution for the depuration of wastewaters produced at pre- and post-harvest level by citrus fruit industries. - Highlights: ► High pesticide amounts are used for pre- and post-harvest treatments of citrus fruits. ► Pesticide-containing wastewaters from citrus production activities require depuration. ► Biobeds is a possible means for the depuration of wastewaters from the citrus industry. ► Biomixture and water management of biobeds were optimized via lab and column studies. ► On-farm offset biobed showed a high dissipation capacity against citrus pesticides. - Biobeds provide an effective solution for the depuration of wastewaters produced by the citrus production industry at both on-farm and post-harvest level.

  10. "Product on Stopper" in a Lyophilized Drug Product: Cosmetic Defect or a Product Quality Concern?

    Science.gov (United States)

    Mehta, Shyam B; Roy, Shouvik; Yang, Han-Chang Cathy

    2018-06-01

    During manufacturing of a lyophilized drug product, operator errors in product handling during loading of product filled vials onto the lyophilizer can lead to a seemingly cosmetic defect which can impact certain critical quality attributes of finished product. In this study, filling of a formulated monoclonal antibody in vials was performed using a peristaltic pump filling unit, and subsequently, the product was lyophilized. After lyophilization, upon visual inspection, around 40% of vials had cosmetic defect with residual product around stopper of the vial and were categorized as "product on stopper" vials, whereas remaining 60% vials with no cosmetic defect were called "acceptable vials." Both groups of vials from 1 single batch were tested for critical quality attributes including protein concentration (ultraviolet absorbance at 280), residual moisture (Karl Fischer), sterility (membrane filtration), and container closure integrity (CCI) (blue dye ingress). Analysis of protein quality attributes such as aggregation, protein concentration, residual moisture showed no significant difference between vials with "product on stopper" and "acceptable vials." However, CCI of the "product on stopper" vials was compromised due to the presence of product around stopper of the vial. The results from this case study demonstrate the following 2 important findings: (1) that a seemingly cosmetic defect may impact product quality, compromising the integrity of the product and (2) that CCI test method can be used as an orthogonal method to sterility testing to evaluate sterility assurance of the product. The corrective action proposed to mitigate this defect is use of a larger sized vial that can potentially minimize this defect that arises because of product handling errors. Copyright © 2018 American Pharmacists Association®. Published by Elsevier Inc. All rights reserved.

  11. Life Cycle Thinking and Integrated Product Deliveries in renovation projects: Extending the concept of Integrated Product Deliveries with Product Service Systems

    DEFF Research Database (Denmark)

    Schipull Kauschen, Jan

    2012-01-01

    extension to the concept of IPDs discussed. Due to extended product responsibility, the concept of PSSs will offer new possibilities of planning and pre-defining life cycles of IPDs more precisely than for regular building components. Reducing or eliminating point-of-sales will induce producers to optimize...

  12. Connecting the Production Multiple

    DEFF Research Database (Denmark)

    Lichen, Alex Yu; Mouritsen, Jan

    &OP process itself is a fluid object, but there is still possibility to organise the messy Production. There are connections between the Production multiple and the managerial technology fluid. The fluid enacted the multiplicity of Production thus making it more difficult to be organised because there were...... in opposite directions. They are all part of the fluid object. There is no single chain of circulating references that makes the object a matter of fact. Accounting fluidity means that references drift back and forth and enact new realities also connected to the chain. In this setting future research may......This paper is about objects. It follows post ANT trajectories and finds that objects are multiple and fluid. Extant classic ANT inspired accounting research largely sees accounting inscriptions as immutable mobiles. Although multiplicity of objects upon which accounting acts has been explored...

  13. Productivity Change and Externalities

    DEFF Research Database (Denmark)

    Kravtsova, Victoria

    2014-01-01

    This paper contributes to the analysis of the impact of externalities on the host country's total factor productivity by taking into account different dimensions of spillover effects. Namely, engagement in exporting and foreign ownership is generally perceived as being beneficial to individual...... firms and the economy as a whole. The approach used in the current research accounts for different internal as well as external factors that individual firms face and evaluates the effect on changes in productivity, technology as well as the efficiency of domestic firms. The empirical analysis focuses...... on Hungary. While the country leads the group of post-socialist countries in the amount of attracted foreign direct investments (FDI) the effect of this policy on the economy remains unclear. The research finds that different externalities play a different role in productivity, technological and efficiency...

  14. Bioethanol production potential from Brazilian biodiesel co-products

    Energy Technology Data Exchange (ETDEWEB)

    Visser, Evan Michael; Filho, Delly Oliveira; Martins, Marcio Aredes [Departamento de Engenharia Agricola, Universidade Federal de Vicosa, Campus Universitario 36570-000 Vicosa, MG (Brazil); Steward, Brian L. [Department of Agricultural and Biosystems Engineering, Iowa State University, 214D Davidson Hall, Ames, IA 50011 (United States)

    2011-01-15

    One major problem facing the commercial production of cellulosic ethanol is the challenge of economically harvesting and transporting sufficient amounts of biomass as a feedstock at biorefinery plant scales. Oil extraction for biodiesel production, however, yields large quantities of biomass co-products rich in cellulose, sugar and starch, which in many cases may be sufficient to produce enough ethanol to meet the alcohol demands of the transesterification process. Soybean, castor bean, Jatropha curcas, palm kernel, sunflower and cottonseed were studied to determine ethanol production potential from cellulose found in the oil extraction co-products and also their capacity to meet transesterification alcohol demands. All crops studied were capable of producing enough ethanol for biodiesel production and, in the case of cottonseed, 470% of the transesterification demand could be met with cellulosic ethanol production from oil extraction co-products. Based on Brazilian yields of the crops studied, palm biomass has the highest potential ethanol yield of 108 m{sup 3} km{sup -2} followed by J. curcas with 40 m{sup 3} km{sup -2}. A total of 3.5 hm{sup 3} could be produced from Brazilian soybean oil extraction co-products. (author)

  15. Tobacco Products Production and Operations Reports

    Data.gov (United States)

    Department of the Treasury — Monthly statistical reports on tobacco products production and operations. Data for Tobacco Statistical Release is derived directly from the Report – Manufacturer of...

  16. Productivity raising approaches in the logistic production system

    Directory of Open Access Journals (Sweden)

    Miroslav Rakyta

    2001-01-01

    Full Text Available This paper deals with the productivity of the logistic production system. The aim is to define the intermediate state of the production machines and equipment (OOE, identification of the material flows, idle time and breakdown forecasting, with the following purchase of the required spare parts. The goal of the system is the satisfaction of the customer´s needs and the minimalisation of not fulfilling the required terms for delivery with simultaneous increasing of the logistic production system productivity.

  17. Development of Commercial-scale Fission Mo-99 Production System

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Seung-Kon; Lee, Suseung; Hong, Soon-Bog; Jang, Kyung-Duk; Park, Ul Jael; Lee, Jun Sig [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2016-10-15

    These days, worldwide {sup 99} Mo supply is not only insufficient but also unstable. Because, most of the main {sup 99}Mo production reactors are more than years old and suffered from frequent and unscheduled shutdown. Therefore, movement to replace old reactors to keep stable supply is now active. Under these conditions, KAERI (Korea Atomic Energy Research Institute) is developing LEU-based fission {sup 99}Mo production process which is connected to the new research reactor (Kijang New Research Reactor, KJRR), which is being constructed in Gijang, Busan, Korea. Historically, the most fission {sup 99}Mo producers have been used highly enriched uranium (HEU) targets so far. However, to reduce the use of HEU in private sector for non-proliferation, {sup 99}Mo producers are forced to convert their HEU-based process to use low enriched uranium (LEU) targets. Economic impact of a target conversion from HEU to LEU is significant. In this study, fission {sup 99}Mo process with non-irradiated LEU targets was presented except separation and purification steps. Pre- and post-irradiation tests of the fission {sup 99}Mo target will be done in 4th quarter of 2016. For the fission Mo production process development, hot experiments with irradiated LEU targets will be done in 4th quarter of 2016. Then, verification of the production process with quality control will be followed until the commercial production of fission {sup 99}Mo scheduled in 2019.

  18. A product feature-based user-centric product search model

    OpenAIRE

    Ben Jabeur, Lamjed; Soulier, Laure; Tamine, Lynda; Mousset, Paul

    2016-01-01

    During the online shopping process, users would search for interesting products and quickly access those that fit with their needs among a long tail of similar or closely related products. Our contribution addresses head queries that are frequently submitted on e-commerce Web sites. Head queries usually target featured products with several variations, accessories, and complementary products. We present in this paper a product feature-based user-centric model for product search involving in a...

  19. Biogas production of Chicken Manure by Two-stage fermentation process

    Science.gov (United States)

    Liu, Xin Yuan; Wang, Jing Jing; Nie, Jia Min; Wu, Nan; Yang, Fang; Yang, Ren Jie

    2018-06-01

    This paper performs a batch experiment for pre-acidification treatment and methane production from chicken manure by the two-stage anaerobic fermentation process. Results shows that the acetate was the main component in volatile fatty acids produced at the end of pre-acidification stage, accounting for 68% of the total amount. The daily biogas production experienced three peak period in methane production stage, and the methane content reached 60% in the second period and then slowly reduced to 44.5% in the third period. The cumulative methane production was fitted by modified Gompertz equation, and the kinetic parameters of the methane production potential, the maximum methane production rate and lag phase time were 345.2 ml, 0.948 ml/h and 343.5 h, respectively. The methane yield of 183 ml-CH4/g-VSremoved during the methane production stage and VS removal efficiency of 52.7% for the whole fermentation process were achieved.

  20. Pre-treatment of Used-Cooking Oil as Feed Stocks of Biodiesel Production by Using Activated Carbon and Clay Minerals

    Directory of Open Access Journals (Sweden)

    Rudy Syah Putra

    2014-02-01

    Full Text Available Many low-cost feedstock i.e. used-cooking oil (UCO for the production of biodiesel fuel (BDF has contained a large amount of water and high proportion of free fatty acids (FFAs. Therefore, a pre-treatment process to reduce the water content (<0.1 wt.% and FFAs (<2.0 wt.% were necessary in order to avoid an undesirable side reactions, such as saponification, which could lead to serious problem of product separation and low fatty acid methyl ester (FAME yield. . In this study, a pre-treatment process of used cooking oil as a feedstock for the production of BDF by using various adsorbents such as Activated Carbon (AC and various clay minerals, for example Smectite (S, Bentonite (B, Kaolinite (K, and Powdered Earthenware (PE were evaluated. The oil obtained from pre-treatment was compared with oil without pre-treatment process. In this study, we reported a basic difference in material ability to the oil, depending on the adsorption condition with respect to the physico-chemical parameters, e.g. refractive index (R, density (ρ, FFAs, and water content (W. The results showed that the water content and FFAs in the oil has decreased when using AC as an adsorbent compared with clay minerals. However, the refractive index of oil has similar with the oil without pre-treatment process as well; meanwhile, the density of oil has increased after the pre-treatment process by using clay minerals.

  1. 75 FR 18015 - Credit for Renewable Electricity Production, Refined Coal Production, and Indian Coal Production...

    Science.gov (United States)

    2010-04-08

    ..., Refined Coal Production, and Indian Coal Production, and Publication of Inflation Adjustment Factors and... coal production, and Indian coal production under section 45. FOR FURTHER INFORMATION CONTACT: Philip... Coal, and Indian Coal:'', Line 26, the language ``is 2.15 cents per kilowatt hour on the'' is corrected...

  2. PDT (Product Data Technology), Production and Society

    DEFF Research Database (Denmark)

    Vesterager, Johan

    1997-01-01

    Information and communication technology (ICT) constitute a genuine technical revolution by enabling a dynamic and flexible support or automation of knowledge and information work. Bearing in mind that products are frozen knowledge, ICT as known will change the way we produce products dramatically....... The use of ICT in engineering of products constitutes product data technology (PDT).This paper presents a a basic platform for an understanding the ongoing revolution with focus on the PDT-area taking outset in the fundamental elements of knowledge and information work: creation, transformation...

  3. Productivity

    DEFF Research Database (Denmark)

    Spring, Martin; Johnes, Geraint; Hald, Kim Sundtoft

    Productivity is increasingly critical for developed economies. It has always been important: as Paul Krugman puts it, “Productivity isn’t everything, but in the long run it is almost everything. A country’s ability to improve its standard of living over time depends almost entirely on its ability...... to raise its output per worker”(Krugman, 1994). Analyses of productivity have, by and large, been the preserve of economists. Operations Management (OM) is rooted in a similar concern for the efficient use of scarce resources; Management Accounting (MA) is concerned with the institutionalised measurement...... and management of productivity. Yet the three perspectives are rarely connected. This paper is a sketch of a literature review seeking to identify, contrast and reconcile these three perspectives. In so doing, it aims to strengthen the connections between policy and managerial analyses of productivity....

  4. Constructing target product profiles (TPPs) to help vaccines overcome post-approval obstacles

    OpenAIRE

    Lee, Bruce Y.; Burke, Donald S.

    2009-01-01

    As history has demonstrated, post-approval obstacles can impede a vaccine’s use and potentially lead to its withdrawal. Addressing these potential obstacles when changes in a vaccine’s technology can still be easily made may improve a vaccine’s chances of success. Augmented vaccine target product profiles (TPPs) can help vaccine scientists better understand and anticipate these obstacles and galvanize conversations among various vaccine stakeholders (e.g., scientists, marketers, business deve...

  5. Novel pre-combustion power production : membrane Reactors

    NARCIS (Netherlands)

    Gallucci, F.; Van Sint Annaland, M.

    2015-01-01

    It is well known that conversion of fossil fuels for power production leads to an enormous amount of greenhouse gas emissions widely accepted as responsible for climate change. As fossil fuels will remain the primary energy source for the next decades, different studies are ongoing to make the

  6. A life cycle assessment of non-renewable energy use and greenhouse gas emissions associated with blueberry and raspberry production in northern Italy

    International Nuclear Information System (INIS)

    Girgenti, Vincenzo; Peano, Cristiana; Bounous, Michele; Baudino, Claudio

    2013-01-01

    This study examined the emissions produced during the pre-farm, farm and post-farm phases of the production cycle of raspberries and giant American whortleberries (blueberries) cultivated in one of the best-adapted areas in northern Italy. The pre-farm phase included the greenhouse gas emissions from the production of plants in the nursery and the transportation of the plants to the production farms. The farm phase involved the emissions of greenhouse gases from chemical products, the water used for irrigation, the generation of waste, and the consumption of electricity and other energy. The post-farm phase comprised the transportation of the products to the distribution centre (DC) and their storage in the DC. The use phase is not included in the system, nor is transportation from the supermarket to the home of the final consumer, but the disposal of the packaging is nevertheless taken into account. Indeed, the use of traditional plastic materials during both the field phase (nursery and cultivation) and the post-harvesting phase (packaging) produced the greatest estimated impact. - Highlights: • LCA is a system for evaluating the environmental sustainability of products and processes. • The disposal of the packaging material is taken into account. • The LCA methodology has been applied to quantify the emissions of berry fruits. • Species index: blueberry and raspberry

  7. A life cycle assessment of non-renewable energy use and greenhouse gas emissions associated with blueberry and raspberry production in northern Italy

    Energy Technology Data Exchange (ETDEWEB)

    Girgenti, Vincenzo, E-mail: vincenzo.girgenti@unito.it [Dipartimento di Scienze Agrarie, Forestali e Alimentari, Università degli Studi di Torino, Via Leonardo da Vinci 44, 10095 Grugliasco, TO (Italy); Peano, Cristiana; Bounous, Michele [Dipartimento di Scienze Agrarie, Forestali e Alimentari, Università degli Studi di Torino, Via Leonardo da Vinci 44, 10095 Grugliasco, TO (Italy); Baudino, Claudio [AgrifruttaSoc. Coop. Agr., Via Beinette 6, 12016 Peveragno, CN (Italy)

    2013-08-01

    This study examined the emissions produced during the pre-farm, farm and post-farm phases of the production cycle of raspberries and giant American whortleberries (blueberries) cultivated in one of the best-adapted areas in northern Italy. The pre-farm phase included the greenhouse gas emissions from the production of plants in the nursery and the transportation of the plants to the production farms. The farm phase involved the emissions of greenhouse gases from chemical products, the water used for irrigation, the generation of waste, and the consumption of electricity and other energy. The post-farm phase comprised the transportation of the products to the distribution centre (DC) and their storage in the DC. The use phase is not included in the system, nor is transportation from the supermarket to the home of the final consumer, but the disposal of the packaging is nevertheless taken into account. Indeed, the use of traditional plastic materials during both the field phase (nursery and cultivation) and the post-harvesting phase (packaging) produced the greatest estimated impact. - Highlights: • LCA is a system for evaluating the environmental sustainability of products and processes. • The disposal of the packaging material is taken into account. • The LCA methodology has been applied to quantify the emissions of berry fruits. • Species index: blueberry and raspberry.

  8. Utilization of Biodiesel By-Products for Biogas Production

    Science.gov (United States)

    Kolesárová, Nina; Hutňan, Miroslav; Bodík, Igor; Špalková, Viera

    2011-01-01

    This contribution reviews the possibility of using the by-products from biodiesel production as substrates for anaerobic digestion and production of biogas. The process of biodiesel production is predominantly carried out by catalyzed transesterification. Besides desired methylesters, this reaction provides also few other products, including crude glycerol, oil-pressed cakes, and washing water. Crude glycerol or g-phase is heavier separate liquid phase, composed mainly by glycerol. A couple of studies have demonstrated the possibility of biogas production, using g-phase as a single substrate, and it has also shown a great potential as a cosubstrate by anaerobic treatment of different types of organic waste or energy crops. Oil cakes or oil meals are solid residues obtained after oil extraction from the seeds. Another possible by-product is the washing water from raw biodiesel purification, which is an oily and soapy liquid. All of these materials have been suggested as feasible substrates for anaerobic degradation, although some issues and inhibitory factors have to be considered. PMID:21403868

  9. Saccharification and hydrolytic enzyme production of alkali pre-treated wheat bran by Trichoderma virens under solid state fermentation.

    Science.gov (United States)

    El-Shishtawy, Reda M; Mohamed, Saleh A; Asiri, Abdullah M; Gomaa, Abu-Bakr M; Ibrahim, Ibrahim H; Al-Talhi, Hasan A

    2015-05-28

    In continuation of our previously interest in the saccharification of agriculture wastes by Bacillus megatherium in solid state fermentation (SSF), we wish to report an investigation and comparative evaluation among Trichoderma sp. for the saccharification of four alkali-pretreated agricultural residues and production of hydrolytic enzymes, carboxymethyl cellulase (CMCase), filter paperase (FPase), pectinase (PGase) and xylanase (Xylase) in SSF. The optimization of the physiological conditions of production of hydrolytic enzymes and saccharification content from Trichoderma virens using alkali-pretreated wheat bran was the last goal. The physico-chemical parameters of SSF include incubation time, incubation temperature, moisture content of the substrate, incubation pH, supplementation with carbon and nitrogen sources were optimized. Saccharification of different solid state fermentation sources wheat bran, date's seeds, grass and palm leaves, were tested for the production of fermentable sugar by Trichoderma sp. The maximum production of hydrolytic enzymes CMCase, FPase, PGase and Xylase and saccharification content were obtained on wheat bran. Time course, moisture content, optimum temperature, optimum pH, supplementation with carbon and nitrogen sources were optimized to achieve the maximum production of the hydrolytic enzymes, protein and total carbohydrate of T. virens using alkali pre-treated wheat bran. The maximum production of CMCase, FPase, PGase, Xylase, protein and carbohydrate content was recorded at 72 h of incubation, 50-70 % moisture, temperature 25-35 °C and pH 5. The influence of supplementary carbon and nitrogen sources was studied. While lactose and sucrose enhanced the activity of PGase from 79.2 to 582.9 and 632.6 U/g, starch inhibited all other enzymes. This was confirmed by maximum saccharification content. Among the nitrogen sources, yeast extract and urea enhanced the saccharification content and CMCase, PGase and Xylase. The results of

  10. EFFECT OF MUSA BALBISIANA COLLA EXTRACT ON BREAST MILK PRODUCTION IN BREASTFEEDING MOTHERS

    Directory of Open Access Journals (Sweden)

    Diyan Wahyuningsih

    2017-07-01

    Full Text Available Background: Musa balbisiana Colla, known as Jantung Pisang Klutuk/Pisang Batu, is considered as a traditional food that can increase breast milk production. Little is known about its benefit in Indonesia. Thus, to examine the impact of musa balbisiana colla on the production of breast milk is needed. Objective: This study aims to examine the effect of the extract of banana flower (Musa balbisiana Colla to increase milk production of breastfeeding mothers. Methods: This was a quasy-experimental study with pre-posttest control group design. This study was conducted in the working area of the Health Center (Puskesmas of Pesantren II in January – February 2017. There were 16 respondents were recruited by accidental sampling, divided to intervention group (8 respondents and control group (8 respondents. Randomization was performed to select the respondent in each group. The quantity of milk production was measured based on the volume of milk production, while the quality of milk production was based on the levels of prolactin in early (pre and late (post using Electro chemilumi-nescence Immunoassay (ECLIA method. Independent t-Test was used to analyze the data. Results: Findings showed that the mean of the volume of the breast milk production in the experiment group was 470.681 ml, and in the control group was 364.650 ml with SD 113.502. While the mean of prolactin levels in the experiment group was 35.337 nanogram, and in the control group was -38.381 nanogram. There was a significant effect of consuming Musa balbisiana Colla extract on the volume of breast milk production (p-value 0.003 and prolactin levels (p-value 0.001 (<0.05. Conclusion: There was a significant effect of banana flower (Musa balbisiana Colla extract on breast milk production and prolactin level in breastfeeding mothers. The findings of this study could be used to be alternative daily menu for postpartum mothers and a solution for midwives to deal with those who have inadequate

  11. Products and environment. Report on integrated product policy

    International Nuclear Information System (INIS)

    2001-01-01

    The National Commission for Sustainable Development established on 16 November 1999 a subgroup which had as one of its tasks to formulate a national strategy or a strategic view on how Finland should promote integrated product policy in accordance with the requirements of sustainable development. The aim of integrated product policy is to improve the environmental friendliness of products and product systems by taking into account the environmental effects during their entire lifecycles. Its leading principles are lifecycle thinking, market-basedness, integration of environmental aspects into economic activity, and that all actors within the product chain (consumers, trade, companies) decrease the environmental consequences of their activities according to the principle of shared responsibility and to their preconditions. Political decision-making and administration should provide firms and clients with the required preconditions and i.a. remove obstacles to knowledge and promote research. In product policy, emphasis is on especially those instruments that encourage actors to develop their activities. At national level, economic instruments should be directed to domestic demand and use of products. It is often most appropriate to develop economic instruments for production and legislation and other regulation within international co-operation. (orig.)

  12. Effect of feeding level pre- and post-puberty and body weight at first calving on growth, milk production, and fertility in grazing dairy cows.

    Science.gov (United States)

    Macdonald, K A; Penno, J W; Bryant, A M; Roche, J R

    2005-09-01

    The effect of feeding to achieve differential growth rates in Holstein-Friesian (HF; n = 259) and Jersey (n = 430) heifers on time to puberty and first lactation milk production was investigated in a 3 x 2 factorial design. Holstein-Friesian and Jersey calves were reared to achieve a BW of 100 and 80 kg, respectively, at 100 d. At target weight, all calves were randomly allocated to one of 3 feeding treatments to achieve different growth rates. Holstein-Friesian and Jersey calves were fed fresh pasture to achieve average daily growth rates of 0.77, 0.53, or 0.37 kg of BW/d (HF) and 0.61, 0.48, or 0.30 kg of BW/d (Jersey), respectively. Period 1 (prepubertal) was imposed until HF and Jersey treatment groups averaged 200 and 165 kg of BW, respectively. Following period 1, HF and Jersey calves from each treatment group were randomly allocated to one of 2 feeding treatments to achieve average daily growth rates of 0.69 or 0.49 kg of BW/d (HF) and 0.58 and 0.43 kg of BW/d (Jersey), respectively. Period 2 (postpubertal) was imposed until 22 mo, when heifers were returned to their farms of origin. Body weight, body condition score, height, heart girth circumference (HGC), milk production, and fertility-related data were collected until the end of the third lactation. Time to reach puberty was negatively associated with level of feeding, and heifers attained puberty at the same BW (251 +/- 25.4 and 180 +/- 24.0 kg for HF and Jersey heifers, respectively). Heifers on high feed allowances during periods 1 and 2 were heavier, taller, and had greater HGC than their slower grown counterparts until 39 mo of age when height and HGC measurements stopped. Body weight differences remained until 51 mo, when measurements ceased. High feed allowance during period 1 (prepubertal) did not affect milk production during the first 2 lactations, but did reduce milk production in lactation 3. It is possible that the expected negative effect of accelerated pre-pubertal growth was masked by

  13. The DWPF strategy for producing an acceptable product

    International Nuclear Information System (INIS)

    Goldston, W.T.; Plodinec, M.J.

    1991-01-01

    The Defense Waste Processing Facility (DWPF) at the Savannah River Site (SRS) will convert the 130 million liters of high-level nuclear waste at SRS into stable borosilicate glass. Production of canistered waste forms by the DWPF is scheduled to begin well before submission of the license application for the first repository. The Department of Energy has defined waste acceptance specifications to ensure that DWPF canistered waste forms will be acceptable for eventual disposal. To ensure that canistered waste forms meet those specifications, a program is being carried out to qualify the waste form and those aspects of the production process which affect product quality. This program includes: Pre-production qualification testing of simulated and actual waste forms; Disciplined demonstrations of the ability to produce an acceptable product during startup testing; and Application of a rigorous product control program during production

  14. Considerations on post-production obligations in terms of Atomic Energy Law

    International Nuclear Information System (INIS)

    Rebentisch, M.

    1992-01-01

    The article describes and evaluates the laws concerning the decommissioning and dismantling of nuclear power plants and offers suggestions for possible new regulations. The contribution examines fundamental legal aspects, the instrumentalization of post-production obligations in terms of atomic energy laws, especially the question as to how to bring the Atomic Energy Law into accord with the Federal Emission Control Law within the realm of decommissioning laws, licences for safe confinement and dismantling of a plant, and in addition questions on making financial provisions for decommissioning. (orig./HSCH) [de

  15. Making Online Products More Tangible: The Effect of Product Presentation Formats on Product Evaluations.

    Science.gov (United States)

    Verhagen, Tibert; Vonkeman, Charlotte; van Dolen, Willemijn

    2016-07-01

    Although several studies have looked at the effects of online product presentations on consumer decision making, no study thus far has considered a potential key factor in online product evaluations: tangibility. The present study aims at filling this gap by developing and testing a model that relates different online product presentation formats to the three-dimensional concept of product tangibility. We test how the three tangibility dimensions influence perceived diagnosticity and, eventually, online purchase intentions. A between-subjects lab experiment (n = 366) was used to test the hypothesized effects of three common online product presentation formats (pictures vs. 360 spin rotation vs. virtual mirror). The results showed that out of these formats, virtual mirrors were superior in providing a sense of product tangibility, followed by the 360-spin rotation format and static pictures. Furthermore, in terms of predictive validity, two of the three tangibility dimensions significantly increased perceived diagnosticity, which, in turn, positively and strongly affected purchase intentions. Overall, our results add to previous works studying the relationships between online product presentation formats and consumer decision making. Also, they hold value for online practitioners by highlighting the potential benefits of applying technologically advanced product presentation formats such as the virtual mirror.

  16. Advances in product family and product platform design methods & applications

    CERN Document Server

    Jiao, Jianxin; Siddique, Zahed; Hölttä-Otto, Katja

    2014-01-01

    Advances in Product Family and Product Platform Design: Methods & Applications highlights recent advances that have been made to support product family and product platform design and successful applications in industry. This book provides not only motivation for product family and product platform design—the “why” and “when” of platforming—but also methods and tools to support the design and development of families of products based on shared platforms—the “what”, “how”, and “where” of platforming. It begins with an overview of recent product family design research to introduce readers to the breadth of the topic and progresses to more detailed topics and design theory to help designers, engineers, and project managers plan, architect, and implement platform-based product development strategies in their companies. This book also: Presents state-of-the-art methods and tools for product family and product platform design Adopts an integrated, systems view on product family and pro...

  17. Managing complexity of product mix and production flow in configure-to-order production systems

    DEFF Research Database (Denmark)

    Myrodia, Anna; Bonev, Martin; Hvam, Lars

    2014-01-01

    In designing configure-to-order production systems for a growing product variety, companies are challenged with an increased complexity for obtaining high productivity levels and cost-effectiveness. In academia several optimization methods and conceptual frameworks for substituting components, or...

  18. Production of GMP certified herbal products in Malaysian Nuclear Agency

    International Nuclear Information System (INIS)

    Daryl Jesus Arapoc; Bohari Yaacob; Zainah Adam

    2015-01-01

    This paper will discuss on up scaling production of herbal product. A pilot scale production plant were developed in Block 37 and equipped with automated and semi-automated production machines which have the capacity to produce 100 thousand pieces of tablet per hour. In order to ensure the quality of the products, raw material inspections, IPQC and FPQC will be done on each batch. Besides that, certification of GMP will be done concurrently. One of the products that will be launch soon is the Mas Cotek tablet. This product is the result of numerous years of researches that had been done in BTP. This includes formulation and production of the product itself. It is hope that more herbal products can be produce in near future. (author)

  19. Exploring the potential of biobeds for the depuration of pesticide-contaminated wastewaters from the citrus production chain: Laboratory, column and field studies

    Energy Technology Data Exchange (ETDEWEB)

    Omirou, M [Agricultural Research Institute, Nicosia (Cyprus); Dalias, P; Costa, C [Agricultural Research Institute, Nicosia (Cyprus); Papastefanou, C; Dados, A [cp FOODLAB LTD, Lefkosia (Cyprus); Ehaliotis, C [Agricultural University of Athens, Department of Natural Resources and Agricultural Engineering, Laboratory of Soils and Agricultural Chemistry, Athens (Greece); Karpouzas, D.G., E-mail: dkarpouzas@bio.uth.gr [University of Thessaly, Department of Biochemistry and Biotechnology, Larisa 41221 (Greece)

    2012-07-15

    The high wastewater volumes produced during citrus production at pre- and post-harvest level presents serious pesticide point-source pollution for groundwater bodies. Biobeds are used for preventing such point-source pollution occurring at farm level. We explored the potential of biobeds for the depuration of wastewaters produced through the citrus production chain following a lab-to-field experimentation. The dissipation of pesticides used pre- or post-harvest was studied in compost-based biomixtures, soil, and a straw-soil mixture. A biomixture of composted grape seeds and skins (GSS-1) showed the highest dissipation capacity. In subsequent column studies, GSS-1 restricted pesticides leaching even at the highest water load (462 L m{sup -3}). Ortho-phenylphenol was the most mobile compound. Studies in an on-farm biobed filled with GSS-1 showed that pesticides were fully retained and partially or fully dissipated. Overall biobeds could be a valuable solution for the depuration of wastewaters produced at pre- and post-harvest level by citrus fruit industries. - Highlights: Black-Right-Pointing-Pointer High pesticide amounts are used for pre- and post-harvest treatments of citrus fruits. Black-Right-Pointing-Pointer Pesticide-containing wastewaters from citrus production activities require depuration. Black-Right-Pointing-Pointer Biobeds is a possible means for the depuration of wastewaters from the citrus industry. Black-Right-Pointing-Pointer Biomixture and water management of biobeds were optimized via lab and column studies. Black-Right-Pointing-Pointer On-farm offset biobed showed a high dissipation capacity against citrus pesticides. - Biobeds provide an effective solution for the depuration of wastewaters produced by the citrus production industry at both on-farm and post-harvest level.

  20. Extending product modeling methods for integrated product development

    DEFF Research Database (Denmark)

    Bonev, Martin; Wörösch, Michael; Hauksdóttir, Dagný

    2013-01-01

    Despite great efforts within the modeling domain, the majority of methods often address the uncommon design situation of an original product development. However, studies illustrate that development tasks are predominantly related to redesigning, improving, and extending already existing products...... and PVM methods, in a presented Product Requirement Development model some of the individual drawbacks of each method could be overcome. Based on the UML standard, the model enables the representation of complex hierarchical relationships in a generic product model. At the same time it uses matrix....... Updated design requirements have then to be made explicit and mapped against the existing product architecture. In this paper, existing methods are adapted and extended through linking updated requirements to suitable product models. By combining several established modeling techniques, such as the DSM...

  1. Consumer concerns and expectations about novel food processing technologies: effects on product liking.

    Science.gov (United States)

    Cardello, Armand V

    2003-06-01

    Eighty-eight consumers participated in a blind pre-test in which they rated their baseline preference for chocolate pudding, their liking of three tasted brands of chocolate pudding, and their level of concern for 20 different food processing and preservation technologies. All returned one month later and tasted the same puddings, but this time they were informed that they had been processed by one of several different novel or traditional food processing techniques. Different sub-groups were informed of the name of the process, the name plus a factual description of the process, or the name, the factual description, plus a benefit statement. Ratings of expected liking were obtained before and after viewing the samples, but before tasting them. Finally, subjects tasted and rated the products for actual liking and a sub-group rated their concern levels for the same 20 technologies rated in the pre-test. Pre-test results showed females to have significantly higher concern levels for all technologies. Individuals who had demonstrated a willingness to consume foods processed by one novel technology (irradiation) had lower concern ratings for all technologies. Ratings of concern were negatively correlated with expected liking for products believed to be processed by the technologies. Expected liking ratings were positively influenced by visual exposure to the product and by a safety and benefit statement. Linear regression of the change in product liking as a function of whether products were better or worse than expected supported an assimilation model of the effect of disconfirmed expectations on liking/disliking. Lastly, post-test concern levels for many of the technologies were reduced by participation in the study.

  2. Ozone production by an atmospheric pulsed discharge with pre-ionization electrodes and partly covered electrode

    International Nuclear Information System (INIS)

    Kaneda, S.; Shimosaki, M.; Hayashi, N.; Ihara, S.; Satoh, S.; Yamabe, C.

    2002-01-01

    In this paper, results on ozone production by atmospheric pulsed discharge, are reported. In the research, two types of ozonizer (Type I and Type II) have been used to investigate improvements of ozone concentration and production efficiency. The ozonizer has plane-to-plane metal electrodes structure, and pre-ionization electrodes are placed on the high voltage electrodes (Type I). In Type II, the surface of grounded electrode with 20 mm of width is covered partly by dielectric (thin rubber) with 11 mm of width, while the geometry of both metal electrodes is same to Type I. In the case of Type I, maximum concentration of about 100 ppm and maximum yield of 70 g/kWh were obtained at input power of 0.3 W. On the other hands, in the case of Type II, 800 ppm and 100 g/kWh were obtained at input power of 1.5 W. It was found that the ozone concentration and production yield were improved by using electrode covered by dielectric. (author)

  3. The production of transplutonium elements in France

    International Nuclear Information System (INIS)

    Koehly, G.; Bourges, J.; Madic, C.; Sontag, R.; Kertesz, C.

    1980-08-01

    The development of the program for the production of transplutonium elements, 241 Am, 243 Am and 244 Cm, in France, required a major effort from the technological and chemical standpoints. Pre-existing hot cells were reconditioned and others specially built for these production operations. From the chemical standpoint, the development of extractive chromatography on the preparative scale has allowed the definition of simple processes. This type of process, initially developed for the treatment of Pu/Al targets, is ideal for the treatment of industrial wastes for their decontamination and for the production of 241 Am

  4. Energy productivity, fertilization rate and profitability of wheat production after various predecessors II.Profitability of wheat production

    Directory of Open Access Journals (Sweden)

    Z. Uhr

    2016-03-01

    Full Text Available Abstract. In the course of our study on the adaptation of modern genotypes common winter wheat (Triticum aestivum to the requirements of sustainable agriculture data were received concerning the influence of the predecessor and nitrogen fertilizer rate on energy efficiency and recyclable nitrogen fertilization and profitability of productivity.We share these data with the scientific community, as they are up-to-date and informative in both theoretical and practical aspects. The analyses are based on data from field experiments fertilizer derived after predecessor cereals – regular crop of sorghum, millet, maize and legumes after predecessor - separate sowing of chickpeas. Energy efficiency of nitrogen fertilization was calculated as the ratio between the energy supplied in the additional grain yield and energy input in the form of fertilizers. Refundable efficiency of nitrogen fertilization is the additional amount of nitrogen accumulated in the grain, with respect to the applied nitrogen fertilization. Economic profitability of production is evaluated by coefficient R = P/Ra (ratio of benefits/costs. The results show that energy efficiency and recyclable nitrogen fertilization are on average five times higher after cereal than after legumes predecessor, and decreased with increasing the fertilizer rate, the decrease was statistically significant only for the first item (exponent. Profitability ratio of production after the introduction of legumes predecessor in crop rotation increases by an average of 42% and retains maximum values of fertilization levels 0.06, 0.12 and 0.18 t/ha nitrogen. Profitability of wheat production using pre-legumes crop is not determined by the parameters nitrogen fertilizer rate and energy efficiency of nitrogen fertilization and refundable efficiency of nitrogen fertilization.

  5. Productivity growth patterns in US dairy products manufacturing plants

    NARCIS (Netherlands)

    Geylani, P.C.; Stefanou, S.E.

    2011-01-01

    We analyse the productivity growth patterns in the US dairy products industry using the Census Bureau's plant-level data set. We decompose Total Factor Productivity (TFP) growth into the scale and technical change components and analyse variability of plants' productivity by constructing transition

  6. A Multiobjective Stochastic Production-Distribution Planning Problem in an Uncertain Environment Considering Risk and Workers Productivity

    Directory of Open Access Journals (Sweden)

    S. M. J. Mirzapour Al-e-Hashem

    2011-01-01

    Full Text Available A multi-objective two stage stochastic programming model is proposed to deal with a multi-period multi-product multi-site production-distribution planning problem for a midterm planning horizon. The presented model involves majority of supply chain cost parameters such as transportation cost, inventory holding cost, shortage cost, production cost. Moreover some respects as lead time, outsourcing, employment, dismissal, workers productivity and training are considered. Due to the uncertain nature of the supply chain, it is assumed that cost parameters and demand fluctuations are random variables and follow from a pre-defined probability distribution. To develop a robust stochastic model, an additional objective functions is added to the traditional production-distribution-planning problem. So, our multi-objective model includes (i the minimization of the expected total cost of supply chain, (ii the minimization of the variance of the total cost of supply chain and (iii the maximization of the workers productivity through training courses that could be held during the planning horizon. Then, the proposed model is solved applying a hybrid algorithm that is a combination of Monte Carlo sampling method, modified -constraint method and L-shaped method. Finally, a numerical example is solved to demonstrate the validity of the model as well as the efficiency of the hybrid algorithm.

  7. Micro Products - Product Development and Design

    DEFF Research Database (Denmark)

    Hansen, Hans Nørgaard

    2003-01-01

    Innovation within the field of micro and nano technology is to a great extent characterized by cross-disciplinary skills. The traditional disciplines like e.g. physics, biology, medicine and engineering are united in a common development process that can only take place in the presence of multi......-disciplinary competences. One example is sensors for chemical analysis of fluids, where chemistry, biology and flow mechanics all influence the design of the product and thereby the industrial fabrication of the product [1]. On the technological side the development has moved very fast, primarily driven by the need...... of the electronics industry to create still smaller chips with still larger capacity. Therefore the manufacturing technologies connected with micro/nano products in silicon are relatively highly developed compared to the technologies used for manufacturing micro products in metals, polymers and ceramics. For all...

  8. Production management (1976)

    International Nuclear Information System (INIS)

    Lee, Sun Ryong

    1976-03-01

    This book introduces production management theory, which gives descriptions of production and system, systems approach, development of production management, Taylor system, Ford system, types of production system, measuring ingredients model of production management, decision of production management, selection of production facilities, arrangement of facilities design of work method and task, work measure system, demanding fore casting, production quality system and credibility system.

  9. Product Customization

    DEFF Research Database (Denmark)

    Hvam, Lars; Mortensen, Niels Henrik; Riis, Jesper

    For the majority of industrial companies, customizing products and services is among the most critical means to deliver true customer value and achieve superior competitive advantage. The challenge is not to customize products and services in itself – but to do it in a profitable way...... from more than 40 product configuration projects in companies providing customer tailored products and services........ The implementation of a product configuration system is among the most powerful ways of achieving this in practice, offering a reduction of the lead time for products and quotations, faster and more qualified responses to customer inquiries, fewer transfers of responsibility and fewer specification mistakes...

  10. The Deployment of Product-Related Environmental Legislation into Product Requirements

    Directory of Open Access Journals (Sweden)

    Daniela C. A. Pigosso

    2016-04-01

    Full Text Available Environmental legislation is increasingly changing its focus from manufacturing-oriented to product-oriented instruments. Compliance with product-related environmental legislation is achieved by the incorporation of environmental requirements into the early phases of the product development process (PDP. Nevertheless, the deployment of product-related environmental legislation into product requirements is still a challenge. This study followed an inductive approach to propose a guideline to support the identification, analysis and deployment of product requirements based on product-related environmental legislation. The guideline is composed of nine steps, clustered into three groups according to their main objective: (A identification of environmental product-related legislation; (B identification of legislative topics to be considered for the deployment of requirements; and (C creation and validation of product requirements. The product requirements deployed are to be considered during the PDP. The guideline was evaluated in an expert consultation in a large manufacturing company, suggesting that it can be used to support the systematization and deployment of product-related environmental requirements.

  11. Utilization of Biodiesel By-Products for Biogas Production

    Directory of Open Access Journals (Sweden)

    Nina Kolesárová

    2011-01-01

    Full Text Available This contribution reviews the possibility of using the by-products from biodiesel production as substrates for anaerobic digestion and production of biogas. The process of biodiesel production is predominantly carried out by catalyzed transesterification. Besides desired methylesters, this reaction provides also few other products, including crude glycerol, oil-pressed cakes, and washing water. Crude glycerol or g-phase is heavier separate liquid phase, composed mainly by glycerol. A couple of studies have demonstrated the possibility of biogas production, using g-phase as a single substrate, and it has also shown a great potential as a cosubstrate by anaerobic treatment of different types of organic waste or energy crops. Oil cakes or oil meals are solid residues obtained after oil extraction from the seeds. Another possible by-product is the washing water from raw biodiesel purification, which is an oily and soapy liquid. All of these materials have been suggested as feasible substrates for anaerobic degradation, although some issues and inhibitory factors have to be considered.

  12. Product numerical range in a space with tensor product structure

    OpenAIRE

    Puchała, Zbigniew; Gawron, Piotr; Miszczak, Jarosław Adam; Skowronek, Łukasz; Choi, Man-Duen; Życzkowski, Karol

    2010-01-01

    We study operators acting on a tensor product Hilbert space and investigate their product numerical range, product numerical radius and separable numerical range. Concrete bounds for the product numerical range for Hermitian operators are derived. Product numerical range of a non-Hermitian operator forms a subset of the standard numerical range containing the barycenter of the spectrum. While the latter set is convex, the product range needs not to be convex nor simply connected. The product ...

  13. Framework for developing product strategy for Configure-To-Order products

    DEFF Research Database (Denmark)

    Myrodia, Anna; Hvam, Lars

    2014-01-01

    Companies producing customized products tend to increase the variety of their product portfolio, in order to fulfill the demand of their customers and align with the competitors. Nevertheless the profitability of the product families may vary greatly. The purpose of this paper is to analyze...... profitability of Configure-To-Order (CTO) products. The framework consists of a 4-step model: Analysis of product assortment, Profitability analysis on configured products, Market and Competitors analysis, Scenarios for future product assortment. The suggested framework is tested on a company. The results...... in terms of product delimitation and experiences gained from the case study are further discussed....

  14. KLE Translog production function and total factor productivity

    Czech Academy of Sciences Publication Activity Database

    Klacek, J.; Vošvrda, Miloslav; Schlosser, Š.

    2007-01-01

    Roč. 87, č. 4 (2007), s. 261-274 ISSN 0322-788X Institutional research plan: CEZ:AV0Z10750506 Keywords : total factor productivity * translog production function * aggregate production function * least squares method * ridge regression Subject RIV: AH - Economics

  15. Clean production and design of products - Complex system and environmental politics of products

    International Nuclear Information System (INIS)

    Sanchez, M.

    1999-01-01

    The orientation of the environmental problem in sustainable terms, especially in the industrialized economies, a new profile in the last years has found. In these economies, the search of a clean production franked by a coherent politics of products and the contribution of the design of products, it have given to the environmental speech a new dimension. With the present text it is sought to respond to the necessity of exploring in Colombia this topic that has a decisive paper inside the instruments of protection of the environment cooperating to improve the quality of life in other latitudes. At the moment the theoretical foundations around the development of products play a important role in the different lines of applied investigation carried out by these countries, especially in the mark of a politics of sustainable development. In spite of the importance of this factor in the industrialized countries where the capacity of integration of a coordinated administration is of great meaning, in Colombia, particularly, the relationship between development and design of products with industry, investigation and political of development and, for our case with a clean production, it is characterized by the scarce insert and attention of this discipline

  16. RPC Production at General Tecnica: a mass scale production

    International Nuclear Information System (INIS)

    Della Volpe, D.; Morganti, S.

    2006-01-01

    The construction of LHC has deeply changed the RPC production. The enormous amount of detector needed and the strong requirements on gas volume quality had a deep impact on the production chain and on the QC and QA at the production site. This basically has brought the RPC from an almost hand-crafted detector to a medium scale mass product. The most critical aspects of the production chain have been modified and/or improved introducing new and more rigorous QC and QA procedures to guarantee the detector quality and improve the management of storage and the procurement on materials. Here it will be presented the work carried on in the last four year at the production site to improve and check the quality and the results achieved. Something like 10000 RPC were produced between 2002 and 2005. Also a preliminary and rough analysis on the efficiencies of the various phases in the chain production based on ATLAS production will be presented

  17. Flour production from shrimp by-products and sensory evaluation of flour-based products

    Directory of Open Access Journals (Sweden)

    Thiago Mendes Fernandes

    2013-08-01

    Full Text Available The objective of this work was to evaluate the production of flour using by-products (cephalothorax obtained from the shrimp (Litopenaeus vannamei industry, and to perform a sensory analysis of shrimp flour-based products. Physicochemical and microbiological analyses on fresh cephalothorax and on manufactured flour were performed, as well as the determination of cholesterol content of this flour, and the sensorial evaluation of soup and pastry made with this flour. By the microbiological analyses, no pathogenic microorganism was detected in the samples. Physicochemical analyses of flour showed high levels of protein (50.05% and minerals (20.97%. Shrimp cephalothorax flour showed high levels of cholesterol. The sensory evaluation indicated a good acceptance of the products, with satisfactory acceptability index (81% for soup, and 83% for pastry, which indicates that shrimp cephalothorax in the form of flour has a potential for developing new products.

  18. Swine production.

    Science.gov (United States)

    Plain, Ronald L; Lawrence, John D

    2003-07-01

    The US swine industry is large and growing. The quantity of pork desired by consumers of US pork is growing at the rate of 1.5%/y. New production systems and new technology have enabled production per sow to grow at a rate of 4% annually in recent years. Consequently, the number of sows in the United States is declining. Because productivity growth is outpacing demand growth, the deflated price of hogs and pork is declining. Hog production and prices continue to exhibit strong seasonal and cyclic patterns. Pork production is usually lowest in the summer and highest in the fall. Production and prices tend to follow 4-year patterns. The US swine industry continues to evolve toward fewer and larger producers who rely on contracts for both hog production and marketing. In 2000, over half of the hogs marketed were from approximately 156 firms marketing more than 50,000 head annually. These producers finished 60% of their production in contract facilities. Over 90% of their marketings were under contract or were owned by a packer. These producers expressed a high level of satisfaction with hog production. Both they and their contract growers were satisfied with production contracts. These large producers were satisfied with their marketing contracts and planned to continue them in the future. The hog industry has changed a great deal in the last decade. There is little reason to believe this rapid rate of change will not continue. This swine industry is highly competitive and profit driven. Profit margins are too small to allow producers the luxury of ignoring new technology and innovative production systems. Consequently, hog production will continue its rapid evolution from traditional agriculture to typical industry.

  19. Production and characterization of enzymatic cocktail produced by Aspergillus niger using green macroalgae as nitrogen source and its application in the pre-treatment for biogas production from Ulva rigida.

    Science.gov (United States)

    Karray, Raida; Hamza, Manel; Sayadi, Sami

    2016-09-01

    Marine macroalgae are gaining more and more importance as a renewable feedstock for durable bioenergy production, but polysaccharides of this macroalgae are structurally complex in its chemical composition. The use of enzymatic hydrolysis may provide new pathways in the conversion of complex polysaccharides to fermentable sugars. In this study, an enzymatic cocktail with high specificity was first isolated from Aspergillus niger using the green macroalgae Ulva rigida as nitrogen source. The cocktail is rich on β-glucosidase, pectinase and carboxy-methyl-cellulase (CMCase). The highest activity was obtained with β-glucosidase (109IUmL(-1)) and pectinase (76IUmL(-1)), while CMCase present the lowest activity 4.6IUmL(-1). The U. rigida pre-treatment with this enzymatic cocktail showed high rate of reduced sugar release, and could bring promising prospects for enzymatic pre-treatment of the biogas production from U. rigida biomass which reached 1175mLgCODint(-1). Copyright © 2016 Elsevier Ltd. All rights reserved.

  20. Stated product formulation preferences for HIV pre-exposure prophylaxis among women in the VOICE-D (MTN-003D) study.

    Science.gov (United States)

    Luecke, Ellen H; Cheng, Helen; Woeber, Kubashni; Nakyanzi, Teopista; Mudekunye-Mahaka, Imelda C; van der Straten, Ariane

    2016-01-01

    The effectiveness of HIV pre-exposure prophylaxis (PrEP) requires consistent and correct product use, thus a deeper understanding of women's stated product formulation preferences, and the correlates of those preferences, can help guide future research. VOICE-D (MTN-003D), a qualitative ancillary study conducted after the VOICE trial, retrospectively explored participants' tablet and gel use, as well as their preferences for other potential PrEP product formulations. We conducted an analysis of quantitative and qualitative data from VOICE-D participants. During in-depth interviews, women were presented with pictures and descriptions of eight potential PrEP product formulations, including the oral tablet and vaginal gel tested in VOICE, and asked to discuss which product formulations they would prefer to use and why. Seven of the original product formulations displayed were combined into preferred product formulation categories based on exploratory factor and latent class analyses. We examined demographic and behavioural correlates of these preferred product formulation categories. In-depth interviews with participants were conducted, coded, and analysed for themes related to product preference. Of the 68 female participants who completed in-depth interviews (22 South Africa, 24 Zimbabwe, 22 Uganda), median age was 28 (range 21-41), 81% were HIV negative, and 49% were married or living with a partner. Four preferred product formulation categories were identified via exploratory factor analysis: 1) oral tablets; 2) vaginal gel; 3) injectable, implant, or vaginal ring; and 4) vaginal film or suppository. A majority of women (81%) expressed a preference for product formulations included in category 3. Characteristics significantly associated with each preferred product category differed. Attributes described by participants as being important in a preferred product formulation included duration of activity, ease of use, route of administration, clinic- versus self

  1. Product Configuration Systems - Implications for Product Innovation and Development

    DEFF Research Database (Denmark)

    Edwards, Kasper; Pedersen, Jørgen Lindgaard

    2004-01-01

    configurations. However, costs are but one parameter on which firms compete and firms must continually innovate new and develop existing products. This paper presents original empirical insights on implementation and use of product configuration systems in a number of Danish industrial firms. The paper discusses...... the organisational changes associated with PCS and how this affects product innovation and development. The paper begins by introducing product configuration systems, which are then placed in context to the firm as a process technology which coordinate different processes: product development, order acquisition......Product Configuration Systems (PCS) is a step in the direction of mass customization in the sense that PCS allows a firm to significantly lower the unit cost of configuration. Thus PCS is a valuable technology for lowering operating costs while retaining a high number of possible product...

  2. Treatment of coaly substances. [production of soluble products

    Energy Technology Data Exchange (ETDEWEB)

    Janner, J; Gonre, O

    1928-05-01

    A process is described for the production of soluble products from coaly substances. The process consists of heating coal or the like under pressure, and if desired with the addition of gases or vapors which do not react to a substantial extent with the coaly matter under the conditions of working. The product may be treated with a solvent at an elevated temperature and under pressure, with or without the addition of said gases or vapors. The products obtained by the above process may be subjected to a further treatment, in particular a cracking process and/or a destructive hydrogenation. The products may also be separated by the aid of suitable solvents into resins, waxes, and other substances.

  3. Productivity Sharing Programs: Can They Contribute to Productivity Improvement?

    Science.gov (United States)

    General Accounting Office, Washington, DC.

    Productivity sharing plans were studied to determine how they operate, what benefits result, and whether long-term increases in productivity can be realized through the program. Thirty-six firms were interviewed that had productivity sharing plans. Nine firms that had either rejected adoption of a productivity sharing plan or were still…

  4. Development and implementation of an herbal and natural product elective in undergraduate medical education.

    Science.gov (United States)

    Karpa, Kelly

    2012-05-22

    Medical students have consistently expressed interest in learning about alternative healing modalities, especially herbal and natural products. To fill this void in medical education at our institution, a novel elective was developed and implemented for fourth year medical students. This herbal/natural product course uses guest lecturers, classroom presentations, and active learning mechanisms that include experiential rotations, case-based learning, and team-based learning to increase student knowledge of herbal/natural product safety and efficacy. Knowledge outcomes were evaluated via administration of a pre- and post-course test (paired student t-test). End-of-course evaluations (Likert-type questions and narrative responses) were used to assess student opinion of knowledge and skills imparted by the elective and overall course content (mean, standard deviation). Over three academic years, 23 students have enrolled in this elective. More than 60% of participants have been female and nearly half of the students (43%) have pursued residencies in primary care. Completion of the course significantly increased student knowledge of common herbal/natural product mechanisms, uses, adverse effects, and drug-interactions as determined by a pre- and post-course knowledge assessment (45%±10% versus 78%±6%; pvariety of activities to which they were exposed and the open classroom discussions that resulted. While students tended to view some alternative medical systems with skepticism, they still believed it was valuable to learn what these modalities encompass. Development and implementation of a herbal/natural product elective that engages undergraduate medical students through active learning mechanisms and critical analysis of the literature has proven effective in increasing knowledge outcomes and is deemed to be a valuable curricular addition by student participants. In the future, it will be of interest to explore mechanisms for expanding the course to reach a larger

  5. Effects of Fermented Milk Products on Bone.

    Science.gov (United States)

    Rizzoli, René; Biver, Emmanuel

    2018-04-01

    Fermented milk products like yogurt or soft cheese provide calcium, phosphorus, and protein. All these nutrients influence bone growth and bone loss. In addition, fermented milk products may contain prebiotics like inulin which may be added to yogurt, and provide probiotics which are capable of modifying intestinal calcium absorption and/or bone metabolism. On the other hand, yogurt consumption may ensure a more regular ingestion of milk products and higher compliance, because of various flavors and sweetness. Bone mass accrual, bone homeostasis, and attenuation of sex hormone deficiency-induced bone loss seem to benefit from calcium, protein, pre-, or probiotics ingestion, which may modify gut microbiota composition and metabolism. Fermented milk products might also represent a marker of lifestyle promoting healthy bone health.

  6. STRATEGIES FOR INCREASING PRODUCTIVITY IN PRODUCTION SYSTEMS

    Directory of Open Access Journals (Sweden)

    Diego Pacheco

    2014-05-01

    Full Text Available The main objective of this article is to point a set of practical strategies that can be adopted to increase the capacity of constraints resources on production systems, when the constraint is inside the factory and not is in the market. To serve this purpose will be presented strategies based on best practices of the Theory of Constraints, Lean Manufacturing and Total Productive Maintenance. This article also presents the mains tools for the deployment of these methodologies. The survey results have provided an objective set of practical strategy that can be used to increase the capacity and productivity of production systems according to the needs of each manufacturing system.

  7. Stabilization of liophilized liposomal products

    Directory of Open Access Journals (Sweden)

    2001-08-01

    Full Text Available Liposomes as a drug carrier have numerous dominancy. Liophilization is the most propr form of these products for long-term maintenance, but this procedure is affected by unstabilizing agent that results in destruction of membrane, release of content and change in size and microbial contamination; hence for prevention of the adverse effects, the protective role of sugars such as: Maltose, Fructose, Glucose, Galactose, Saccharose and Lactose were studied. For this purpose, after preparation of liposomal suspention, categorized in for duplicate groups and concentrations of 25, 50, 100 percent of these sugars were added to those. On the basis of color and consistency of products, the best method of freezing is as application of absolute alcohol and then chilling in-70 oc for 16 h. In survey of protective substances concentrations 0.7, 1.4, 2.8, and 5.6 percent of the mentioned sugars were used for calculating of leakage percent (Upon on the ratio of optical density of treated samples to untreated. In this study, released maltose had highest effect. Level of fusion and aggregation had any significant difference between pre and post lyophilized samples in centrifugation with 10000 rpm. Microbial state of recent samples were studied by culturing in SCD and SCDA media that indicated microbial growth in both samples.     

  8. Productivity and cost of harvesting a stemwood biomass product from integrated cut-to-length harvest operations in Australian Pinus radiata plantations

    International Nuclear Information System (INIS)

    Walsh, D.; Strandgard, M.

    2014-01-01

    Significant quantities of woody biomass from the tops of trees and larger woody ‘waste’ pieces that fall outside existing sawlog and pulpwood specifications are left on site post final harvest in Australian radiata Pinus radiata (D. Don) (radiata pine) plantations. Woody biomass is a potential product for pulp making or energy generation. Commercial use of woody biomass from radiata pine plantations would add extra value to the Australian plantation estate through improved resource utilisation, and potentially reduced post-harvesting silvicultural costs. This study investigated the productivity and cost impact of the harvest and extraction to roadside of woody biomass in an integrated harvest operation in a typical Australian two machine (harvester/processor and forwarder), cut-to-length, clearfall operation in a mature, thinned radiata pine plantation. The harvest operation yielded 23 GMt/ha (5% of the total yield) of woody biomass (known as ‘fibreplus’), 443 GMt/ha of sawlogs and 28 GMt/ha of pulpwood. The mean quantity of biomass left on site was 128 GMt/ha, mainly consisting of branches and needles, sufficient to minimise nutrient loss and protect the soil from erosion. Woodchips derived from the fibreplus product were suitable for kraft pulp making, (when blended in small amounts with clean de-barked roundwood woodchips), and for energy generation. The method trialed with the fibreplus product being produced did not impact harvesting and processing productivity and costs, but extraction was 14% less productive. Through analysis of the productivities of each phase and development of a cost model the harvest and extraction of the fibreplus product was estimated to increase total unit costs by ∼4.9%. - Highlights: • Study of the productivity and cost impact of producing a woody biomass product. • We compared two scenarios – harvesting with and without the biomass product. • An additional 23 GMt/ha (5% of the total yield) of woody biomass

  9. Product Service Systems

    DEFF Research Database (Denmark)

    Departing from Product Development models based on physical artefacts. Moving towards integrated Product Development and System Operations models suited Product/Service-systems......Departing from Product Development models based on physical artefacts. Moving towards integrated Product Development and System Operations models suited Product/Service-systems...

  10. An Intelligent Method of Product Scheme Design Based on Product Gene

    Directory of Open Access Journals (Sweden)

    Qing Song Ai

    2013-01-01

    Full Text Available Nowadays, in order to have some featured products, many customers tend to buy customized products instead of buying common ones in supermarket. The manufacturing enterprises, with the purpose of improving their competitiveness, are focusing on providing customized products with high quality and low cost as well. At present, how to produce customized products rapidly and cheaply has been the key challenge to manufacturing enterprises. In this paper, an intelligent modeling approach applied to supporting the modeling of customized products is proposed, which may improve the efficiency during the product design process. Specifically, the product gene (PG method, which is an analogy of biological evolution in engineering area, is employed to model products in a new way. Based on product gene, we focus on the intelligent modeling method to generate product schemes rapidly and automatically. The process of our research includes three steps: (1 develop a product gene model for customized products; (2 find the obtainment and storage method for product gene; and (3 propose a specific genetic algorithm used for calculating the solution of customized product and generating new product schemes. Finally, a case study is applied to test the usefulness of our study.

  11. Protein-carbohydrate supplements in the production of meat products

    Directory of Open Access Journals (Sweden)

    I. N. Tolpigina

    2013-01-01

    Full Text Available Rationality of the use of protein-carbohydrate additive in the technology of meat products was justified. The capability of the fiber to stabilizate properties of meat systems was investigated. There was established permissible limits of the use of additives in prescription solutions in the production of sausage products of a various price level according to the criterion of biological values. The trial production of sausage products was held. By the methods of mathematical statistics were optimized compositions of protein-polysaccharide additives.

  12. Effects of blood products on inflammatory response in endothelial cells in vitro.

    Directory of Open Access Journals (Sweden)

    Martin Urner

    Full Text Available BACKGROUND: Transfusing blood products may induce inflammatory reactions within the vascular compartment potentially leading to a systemic inflammatory response. Experiments were designed to assess the inflammatory potential of different blood products in an endothelial cell-based in vitro model and to compare baseline levels of potentially activating substances in transfusion products. METHODS: The inflammatory response from pre-activated (endotoxin-stimulated and non-activated endothelial cells as well as neutrophil endothelial transmigration in response to packed red blood cells (PRBC, platelet concentrates (PC and fresh frozen plasma (FFP was determined. Baseline inflammatory mediator and lipid concentrations in blood products were evaluated. RESULTS: Following incubation with all blood products, an increased inflammatory mediator release from endothelial cells was observed. Platelet concentrates, and to a lesser extent also FFP, caused the most pronounced response, which was accentuated in already pre-stimulated endothelial cells. Inflammatory response of endothelial cells as well as blood product-induced migration of neutrophils through the endothelium was in good agreement with the lipid content of the according blood product. CONCLUSION: Within the group of different blood transfusion products both PC and FFP have a high inflammatory potential with regard to activation of endothelial cells. Inflammation upon blood product exposure is strongly accentuated when endothelial cells are pre-injured. High lipid contents in the respective blood products goes along with an accentuated inflammatory reaction from endothelial cells.

  13. HIGH PRODUCTIVITY VACUUM BLASTING SYSTEM

    International Nuclear Information System (INIS)

    McPhee, William S.

    1999-01-01

    The objective of this project is to improve the productivity and lower the expense of existing vacuum blasting technology. This technology is used to remove radioactive contamination, PCBs, and lead-based paint and provides worker protection by continuously recycling the material and dust for the decontamination tasks. The proposed work would increase the cleaning rate and provide safe and cost-effective decontamination of the DOE sites. This work focuses on redesigning and improving existing vacuum blasting technology including blast head nozzles, ergonomic handling of the blast head by reducing its weight; brush-ring design, vacuum level regulator, efficiency of the dust separator, and operational control sensors. The redesign is expected to enhance the productivity and economy of the vacuum blasting system by at least 50% over current vacuum blasting systems. There are three phases in the project. Phase I consists of developing and testing mathematical models. Phase II consists of pre-prototype design and fabrication and pre-prototype unit testing. Phase III consists of prototype design and field verification testing. In phase I, mathematical models are developed and analyzed for the nozzle, blast head, wind curtain, and dust separator, first as individual devices and then combined as an integrated model. This allows study of respective airflow and design parameters. The Contractor shall, based on the results of the mathematical modeling studies, design experimental models of the components and test these models. In addition, the Contractor shall develop sensors to detect the relationship of the blast head to the blast surfaces and controls to minimize the dependency on an operator's skill and judgment to obtain optimum positioning, as well as real-time characterization sensors to determine as the blast head is moving the depth to which coatings must be removed, thereby improving production and minimizing waste. In phase II, the Contractor shall design and

  14. Talking about tobacco on Twitter is associated with tobacco product use.

    Science.gov (United States)

    Unger, Jennifer B; Urman, Robert; Cruz, Tess Boley; Majmundar, Anuja; Barrington-Trimis, Jessica; Pentz, Mary Ann; McConnell, Rob

    2018-06-10

    Tobacco-related content appears on social media in the form of advertising and messages by individuals. However, little is known about associations between posting social media messages and tobacco product use among adolescents and young adults. Self-reports of tobacco product use were obtained from the Children's Health Study of young adults in Southern California. Among the 1486 respondents in the most recent wave of the cohort (2016-2017), 284 provided tobacco product use data and their Twitter user names to access publicly available Twitter account data (mean age = 20.1 yrs. (SD = 0.6), 54% female, 49% Hispanic). We obtained the tweets that those respondents posted on Twitter, searched the tweets for 14 nicotine- and tobacco-related keywords, and coded these statements as positive or negative/neutral. Logistic regression analyses were conducted to determine whether respondents who posted positive tobacco-related tweets were more likely to report tobacco product use, relative to those who did not post any positive tobacco-related tweets. Respondents who posted any positive messages about tobacco had significantly higher odds of reporting past month use of cigarettes (OR = 3.15, 95% CI = 1.36, 7.30) and any tobacco product (OR = 2.41, 95% CI = 1.16, 5.01), relative to respondents who did not post about tobacco. This is the first study to establish an empirical link between adolescents' and young adults' tobacco-related Twitter activity and their tobacco product use. Health communications about the risks of tobacco use could target adolescents who post positive messages about tobacco products on Twitter. Copyright © 2018 Elsevier Inc. All rights reserved.

  15. Tobacco Products

    Science.gov (United States)

    ... Exposure is High in Multiunit Housing Smokeless Products Electronic Cigarettes Youth Tobacco Prevention Tobacco Products Tobacco Ingredient ... Tweet Share Compartir Find Fact Sheets on Products (Cigars, Bidis and Betel Quid with Tobacco (Gutka) and ...

  16. 77 FR 75377 - Product List Update

    Science.gov (United States)

    2012-12-20

    ... Service International Business Reply Mail Service Money Orders Post Office Box Service Stamp Fulfillment... International Business Reply Mail Service Money Orders Post Office Box Service [Reserved for Product Description...) International Business Reply Service Competitive Contract 1 (MC2009-14 and CP2009-20) International Business...

  17. Designing Product Families

    DEFF Research Database (Denmark)

    Pedersen, Per Erik Elgård; Miller, Thomas Dedenroth

    1998-01-01

    Manufacturing companies that operate with products aimed at different market segments and applications are experiencing an increasing demand from customers who expect products to be tailored to their exact needs rather than accepting general products based on average customer needs. This trend ha......: Variety, Design Principles, and Product Maturity.......Manufacturing companies that operate with products aimed at different market segments and applications are experiencing an increasing demand from customers who expect products to be tailored to their exact needs rather than accepting general products based on average customer needs. This trend has...... led to a new business paradigm, "mass customization", where companies strive to provide highly customized products while still maintaining the efficiency of the classical mass production enterprise. One of the key factors in mass customization has been efficient use of product platforms...

  18. Charcoal production and environmental degradation

    International Nuclear Information System (INIS)

    Hosier, R.H.

    1993-01-01

    This paper examines the environmental impacts of continued tree harvesting for charcoal production to supply the urban areas in Tanzania. Woodlands appear to recover relatively well following harvesting for charcoal production. Selective harvesting, where the high quality, low cost fuel production species and specimens are culled first from a piece of land, serves to maintain the viability of the woodlands resource while providing charcoal. This recovery period can be prolonged through any number of human induced activities, such as heavy grazing, multiple burns and extended cultivation periods. At the same time, post-harvest management techniques, such as coppice management, sprout protection and fertilization, can also improve the ability of woodlands to recover following harvesting. The environmental history of a given area determines why certain areas continue to be strong suppliers of woodfuel while others are not. For example, Shinyanga started from a low productivity base and has been degraded by successive waves of tree harvesting compounded by heavy grazing pressure. It is this multiple complex of pressures over a long period of time on land which is intrinsically of low productivity, and not the harvesting of woodlands for fuels, which has led to the environmental degradation in these areas. (author)

  19. Biohydrogen production from organic waste and wastewater by dark fermentation. A promising module for renewable energy production

    Energy Technology Data Exchange (ETDEWEB)

    Krupp, M.

    2007-07-01

    Fossil fuels are limited and global warming due to increased CO{sub 2}-emissions may lead to worldwide environmental disasters. Therefore energy production from renewable sources is the most important task in the future. In the contribution under consideration, the author reports on biohydrogen production from organic waste and wastewater by dark fermentation.An engineered approach was chosen to get more information about the technical feasibility of a process which has been studied intensively in the current century. The developed test method represents a functional tool for determination of the biohydrogen production potential of a wide variety of different substances. The implementation of the 'glucose equivalent' for estimation of the biohydrogen potential of a certain substrate was a successfull approach. With this parameter, the biohydrogen potential could be evaluated properly without severe influence from the boundary conditions. Within the continuous test trials it could be found that continuous biohydrogen production in a 30 L-scale is feasible without costly regulation and control mechanisms. The further test series conducted in 30 L-scale gave important results for pilot plant design. One main result of the test runs is that it was shown that the control mechanisms could be reduced to a simple pH-regulation by addition of sodium hydroxide. Other parameters like organic loading rate (OLR) and hydraulic retention time (HRT) were clearly more important to ensure a stable continuous process. A HRT of 15-20 hours combined with an OLR of up to 14 kg VS/(d m{sup 3}) resulted in very high hydrogen yields of 2.14-2.56 mol H{sub 2}/mol glucose. Another important result for pilot plant construction was the necessity of input cooling. Due to ambient temperatures in the input vessels the substrate tests failed. Hydrolysis took place in the input vessels, not in the reactors. Gas upgrading by membrane systems was tested as well as post-methanisation or

  20. Convolution-wedge product of fields

    International Nuclear Information System (INIS)

    Diep, D.N.; Duc, D.V.; Tan, H.V.; Viet, N.A.

    2007-07-01

    In this paper we use the pair of electric-magnetic (or GNO, or Langlands) duality groups G = Sp(1) and L G = SO(3) and the T-transformation in mirror symmetry (or the S-duality, or the Fourier-Mukai transformation) to define the wedge product of fields: first by using gauge transformation, we reduce the fields with values in LieG = sp(1) to the fields with values in the Lie algebra of the maximal torus t subset of LieG = sp(1). Next we use the Fourier-Mukai transformation of fields to have the images as fields with values in the Lie algebra of the Langlands dual torus L t in Lie L G = so(3). The desired wedge product of two fields is defined as the pre-image of the ordinary wedge product of images with values in L t subset of so(3). (author)

  1. Antimicrobial Peptide Production and Purification.

    Science.gov (United States)

    Suda, Srinivas; Field, Des; Barron, Niall

    2017-01-01

    Antimicrobial peptides (AMPs) are natural defense compounds which are synthesized as ribosomal gene-encoded pre-peptides and produced by all living organisms. AMPs are small peptides, usually cationic and typically have hydrophobic residues which interact with cell membranes and have either a narrow or broad spectrum of biological activity. AMPs are isolated from the natural host or heterologously expressed in other hosts such as Escherichia coli. The proto-typical lantibiotic Nisin is a widely used AMP that is produced by the food-grade organism Lactococcus lactis. Although AMP production and purification procedures require optimization for individual AMPs, the Nisin production and purification protocol outlined in this chapter can be easily applied with minor modifications for the production and purification of other lantibiotics or AMPs. While Nisin is produced and secreted into the supernatant, steps to recover Nisin from both cell-free supernatant and cell pellet are outlined in detail.

  2. Verification and Enhancement of VIIRS Day-Night Band Power Outage Detection Product

    Science.gov (United States)

    Burke, A.; Schultz, L. A.; Omitaomu, O.; Molthan, A.; Cole, T.; Griffin, R.

    2017-12-01

    The NASA SPoRT (Short-term Prediction Research and Transition) Center has collaborated with scientists at NASA Goddard Space Flight Center to create a power outage detection product from radiance data obtained by the VIIRS (Visible Infrared Imaging Radiometer Suite) sensor aboard the Suomi-NPP satellite. This product uses a composite of pre-event radiance values from the VIIRS Day-Night Band to establish a baseline of "normal" nighttime lights for a study area. Then, after a severe weather event or other disaster, post-event images are compared to the composite to generate a percent-of-normal radiance product to identify areas that are experiencing outages and to aid in disaster response and monitor recovery. This project will use ground-truth county-level outage data provided by Oak Ridge National Laboratory (ORNL) in order validate the product and to establish a percent-of-normal threshold for identifying power outages. Once a threshold is found, ORNL's LandScan Global population data will be combined with the product to estimate how many electrical customers are being affected by power outages after a disaster. Two case studies will be explored to examine power outage recovery after severe weather events, including Hurricane Matthew from 2016 and the Washington D.C. Derecho event of 2012.

  3. Product Family Assessment

    DEFF Research Database (Denmark)

    Kvist, Morten

    their focus from single products to entire product families and try to incorporate the development of product variety into a future product family. The key is to create fit between the product design and production setup. The challenge of understanding this fit and modelling dispositional relations between...... and on the ideas of lean production, plus experiences from the industrial collaboration. The idea of waste from the lean philosophy is brought into a product variety context, and discussed in relation to product development. Verification of the model has been carried out in an industrial setting at Danfoss......This thesis reports the results of a PhD project from the Technical University of Denmark. The research has been carried out in a collaborative project with the Danish company Danfoss Automatic Controls. In the global market companies are struggling to meet customers’ expectation of products...

  4. Product (RED)

    DEFF Research Database (Denmark)

    Ponte, Stefano

    2011-01-01

    ) and the consumers who buy iconic brand products to help ‘distant others’. While in many other forms of causumerism, labels or certification systems ‘prove’ that a product is just, in RED, aid celebrities provide the proof. From the consumer point of view both labels and celebrities provide a similar simplification...... of complex social, economic, and environmental processes. At the same time, we argue that there are important distinctions as well—labels and certifications are ultimately about improving the conditions of production, whereas RED is about accepting existing production and trade systems and donating......(PRODUCT)RED™ (hereafter RED) is a cobranding initiative launched in 2006 by the aid celebrity Bono to raise money from product sales to support The Global Fund to Fight AIDS, Tuberculosis and Malaria. In this paper we argue that RED is shifting the boundaries of ‘causumerism’ (shopping...

  5. Production management (2000)

    International Nuclear Information System (INIS)

    Jung, Chung Yeong

    2000-08-01

    This book includes basic concept of production management, production system, strategy and mission of production, decision of production management, operation of decision making, life cycle of items and development, value of productions, design for reliability of productions, equipment layout and manufacturing process, quantitative forecast, schedule plan, inventory system, concept, input and output of MRP, Montekalo simulation, quality management, and automation system.

  6. Refreshing Rubbers as Customized Photothermal Conversion Materials through Post-Darkening Modeling Production.

    Science.gov (United States)

    Li, Ruiting; Wang, Zhen; Han, Peng; He, Yonglin; Zhang, Xiaohong; Wang, Yapei

    2017-12-19

    Organic conjugated polymers with low energy bandgaps are emerging as a particular class of near-infrared (NIR) photothermal conversion materials. However, these polymers routinely possess high phase transition temperatures due to the rigid skeleton and strong intermolecular interactions. Conjugated polymers can rarely be thermally processed at low temperature, especially below 100 °C. This work formulates a concept of post-darkening modeling production (p-DMP) by which the thermoplastic non-conjugated trans-polyisoprene (TPI) is refreshed into a photothermal conversion material with high light use efficiency. Two steps, including the customizable shaping at low temperature and iodine vapor-tailored "darkening", ensure the ease of preparing photothermal conversion devices with desirable topologies. A few characterizations, with the combination of density functional theory (DFT) calculations, provide reasonable explanations for understanding the "darkening" process of TPI in iodine atmosphere. In particular, the p-DMP is successfully extended to three-dimension (3D) printing, opening an avenue to fabricate personalized photothermal products, for example, a sunlight-directed physiotherapy device for healthcare of articular tissues. © 2017 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

  7. Radioactivity of food products in the region of the ''Kozloduj'' atomic power station in the pre-exploitation period

    International Nuclear Information System (INIS)

    Jotov, M.; Petkov, T.; Zlatanova, R.; Boyadzhiev, A.

    1976-01-01

    The pre-exploitation status of the region of the ''Kozloduj'' atomic power stationand its torch zone, regarding the concentration of the biologically most dangerous artificial isotopes in the basic food products was determined. The tested foods were milk, meat, wheat, fish and grapes produced at the most important and basic production regions in the controled region. The radioactive isotope concentrations in the analyzed food produxts are reported. They will serve as a basis in assessing any eventual additional contamination of the region as a result of the work of the ''Kozloduj'' electric power station. (author)

  8. Danish initiatives to improve the safety of meat products

    DEFF Research Database (Denmark)

    Wegener, Henrik Caspar

    2010-01-01

    and Campylobacter, and to a lesser extent Yersinia, Escherichia coli O157 and Listeria. Danish initiatives to improve the safety of meat products have focused on the entire production chain from the farm to the consumer, with a special emphasis on the pre-harvest stage of production. The control of bacterial......During the last two decades the major food safety problems in Denmark, as determined by the number of human patients, has been associated with bacterial infections stemming from meat products and eggs. The bacterial pathogens causing the majority of human infections has been Salmonella...

  9. Extrusion product defects: a statistical study

    International Nuclear Information System (INIS)

    Qamar, S.Z.; Arif, A.F.M.; Sheikh, A.K.

    2003-01-01

    In any manufacturing environment, defects resulting in rework or rejection are directly related to product cost and quality, and indirectly linked with process, tooling and product design. An analysis of product defects is therefore integral to any attempt at improving productivity, efficiency and quality. Commercial aluminum extrusion is generally a hot working process and consists of a series of different but integrated operations: billet preheating and sizing, die set and container preheating, billet loading and deformation, product sizing and stretching/roll-correction, age hardening, and painting/anodizing. Product defects can be traced back to problems in billet material and preparation, die and die set design and maintenance, process variable aberrations (ram speed, extrusion pressure, container temperature, etc), and post-extrusion treatment (age hardening, painting/anodizing, etc). The current paper attempts to analyze statistically the product defects commonly encountered in a commercial hot aluminum extrusion setup. Real-world rejection data, covering a period of nine years, has been researched and collected from a local structural aluminum extrusion facility. Rejection probabilities have been calculated for all the defects studied. The nine-year rejection data have been statistically analyzed on the basis of (i) an overall breakdown of defects, (ii) year-wise rejection behavior, (iii) breakdown of defects in each of three cost centers: press, anodizing, and painting. (author)

  10. PRODUCTION OF CARBON PRODUCTS USING A COAL EXTRACTION PROCESS

    Energy Technology Data Exchange (ETDEWEB)

    Dady Dadyburjor; Philip R. Biedler; Chong Chen; L. Mitchell Clendenin; Manoj Katakdaunde; Elliot B. Kennel; Nathan D. King; Liviu Magean; Peter G. Stansberry; Alfred H. Stiller; John W. Zondlo

    2004-08-31

    This Department of Energy National Energy Technology Laboratory sponsored project developed carbon products, using mildly hydrogenated solvents to extract the organic portion of coal to create synthetic pitches, cokes, carbon foam and carbon fibers. The focus of this effort was on development of lower cost solvents, milder hydrogenation conditions and improved yield in order to enable practical production of these products. This technology is needed because of the long-term decline in production of domestic feedstocks such as petroleum pitch and coal tar pitch. Currently, carbon products represents a market of roughly 5 million tons domestically, and 19 million tons worldwide. Carbon products are mainly derived from feedstocks such as petroleum pitch and coal tar pitch. The domestic supply of petroleum pitch is declining because of the rising price of liquid fuels, which has caused US refineries to maximize liquid fuel production. As a consequence, the long term trend has a decline in production of petroleum pitch over the past 20 years. The production of coal tar pitch, as in the case of petroleum pitch, has likewise declined significantly over the past two decades. Coal tar pitch is a byproduct of metallurgical grade coke (metcoke) production. In this industry, modern metcoke facilities are recycling coal tar as fuel in order to enhance energy efficiency and minimize environmental emissions. Metcoke production itself is dependent upon the production requirements for domestic steel. Hence, several metcoke ovens have been decommissioned over the past two decades and have not been replaced. As a consequence sources of coal tar are being taken off line and are not being replaced. The long-term trend is a reduction in coal tar pitch production. Thus import of feedstocks, mainly from Eastern Europe and China, is on the rise despite the relatively large transportation cost. To reverse this trend, a new process for producing carbon products is needed. The process must be

  11. The pathways for small holder apiculture production in Swaziland ...

    African Journals Online (AJOL)

    The apiculture production pathways were identified as training (pre-farming and during farming), production materials and equipment, apiary environmental requirements and business skills. The qualitative results were summarised into theft of bee-hives, absconding of bees, business management problems and financial ...

  12. Effect of pig dung fertilizer on zooplankton production

    African Journals Online (AJOL)

    SARAH

    2014-12-29

    Dec 29, 2014 ... Key-words: pig dung, fertilization, zooplankton production. ... an already widespread practice in many Asian countries (fukusho, et al., ..... Elsevier Scientific Publishing Company,. New York ... Effect on Water Quality, pond productivity and. Growth of ... McQueen DJ, Johannes MRS, Post JR, Stewart TJ, Lean.

  13. Fission products and nuclear fuel behaviour under severe accident conditions part 3: Speciation of fission products in the VERDON-1 sample

    Science.gov (United States)

    Le Gall, C.; Geiger, E.; Gallais-During, A.; Pontillon, Y.; Lamontagne, J.; Hanus, E.; Ducros, G.

    2017-11-01

    Qualitative and quantitative analyses on the VERDON-1 sample made it possible to obtain valuable information on fission product behaviour in the fuel during the test. A promising methodology based on the quantitative results of post-test characterisations has been implemented to assess the release fraction of non γ-emitter fission products. The order of magnitude of the estimated release fractions for each fission product was consistent with their class of volatility.

  14. Phosphodiesterase-5 inhibitors and their analogues as adulterants of herbal and food products: analysis of the Malaysian market, 2014-16.

    Science.gov (United States)

    Bujang, Nur Baizura; Chee, Chin Fei; Heh, Choon Han; Rahman, Noorsaadah Abd; Buckle, Michael J C

    2017-07-01

    Adulteration of herbal health supplements with phosphodiesterase-5 (PDE-5) inhibitors and their analogues is becoming a worldwide problem. The aim of this study was to investigate herbal and food products sold in the Malaysian market for the presence of these adulterants. Sixty-two products that claim to enhance men's sexual health were sampled between April 2014 and April 2016. These products included unregistered products seized by the Pharmacy Enforcement Division of the Ministry of Health (n = 39), products sent to the National Pharmaceutical Regulatory Agency for pre-registration testing (n = 9) and products investigated under the post-registration market surveillance programme (n = 14). The products were tested against an in-house spectral library consisting of 61 PDE-5 inhibitors and analogues using a validated liquid chromatography-mass spectrometry ion-trap-time-of-flight (LC-MS IT-TOF) method. Thirty-two (82%) of the unregistered products and two (14%) of the registered products were found to be adulterated with at least one PDE-5 inhibitor or analogue, while none of the pre-registration products contained adulterants. A total of 16 different adulterants were detected and 36% of the adulterated products contained a mixture of two or more adulterants. This study has demonstrated that the adulteration of unregistered herbal products in the Malaysian market is an alarming issue that needs to be urgently addressed by the relevant authorities.

  15. Enhancing methane production from U. lactuca using combined anaerobically digested sludge (ADS) and rumen fluid pre-treatment and the effect on the solubilization of microbial community structures.

    Science.gov (United States)

    Zou, Yu; Xu, Xiaochen; Li, Liang; Yang, Fenglin; Zhang, Shushen

    2018-04-01

    Methane production by the anaerobic digestion of seaweed is restricted by the slow degradation caused by the influence of the rigid algal cell wall. At the present time, there has been no study focusing on the anaerobic digestion of U. lactuca by co-fermentation and pre-treatment with rumen fluid. Rumen fluid can favor methane production from algal biomass by utilizing the diversity and quantity of bacterial and archaeal communities in the rumen fluid. This research presents a novel method based on combined ADS and rumen fluid pre-treatment to improve the production of methane from seaweed. Biochemical methane potential (BMP) tests were performed to investigate the biogas production using combined ADS and rumen fluid pre-treatment at varied inoculum ratios on the performance of methane production from U. lactuca biomass. Compared to the control (no rumen fluid pre-treatment), the highest BMP yields of U. lactuca increased from 3%, 27.5% and 39.5% to 31.1%, 73% and 85.6%, respectively, for three different types of treatment. Microbial community analysis revealed that the Methanobrevibacter species, known to accept electrons to form methane, were only detected when rumen fluid was added. Together with the significant increase in species of Methanoculleus, Methanospirillum and Methanosaeta, rumen fluid improved the fermentation and degradation of the microalgae biomass not only by pre-treatment to foster cell-wall degradation but also by relying on methane production within itself during anaerobic processes. Batch experiments further indicated that rumen fluid applied to the co-fermentation and pre-treatment could increase the economic value and hold promise for enhancing biogas production from different seaweed species. Copyright © 2017 Elsevier Ltd. All rights reserved.

  16. Wood as Energy--Production and Marketing. Instructional Materials Developed for Iowa Teachers of Vocational Agriculture.

    Science.gov (United States)

    Iowa State Univ. of Science and Technology, Ames. Dept. of Agricultural Education.

    Instructional materials are provided for a unit dealing with production and marketing of wood as an energy source. Unit objectives and a list of visual masters appear first. Content is arranged by six topics: introduction, pre-cutting activities (planning a fuelwood cutting, marketing, chain saw safety), cutting activities, post-cutting…

  17. Productivity improvement with green approach to palm oil factory productivity

    Science.gov (United States)

    Matondang, N.

    2018-02-01

    The palm oil factory (POF) processes fresh fruit bunches into crude palm oil (CPO) and palm kernel oil (PKO) by products in the form of liquid and solid waste. One of the solid wastes produced in POF Tanjung Kasau is empty fruit bunches of palm oil (FBPO) which have been burned completely on incinerator tubes so that potentially produces pollutants that pollute the environment. If FBPO waste is managed properly, it will improve the productivity of the company. Therefore, it is necessary to conduct a study to find out how far the increased productivity of the company can reduce their impact on the environment, if FBPO is used as raw material of liquid smoke. The productivity improvement approach is done by Green Productivity concept, by looking at three aspects: environmental, social and economical. Green Productivity aims to protect the environment simultaneously by increasing the productivity of the company. One way is to turn FBPO waste into liquid smoke product is by pyrolysis process. The results showed that turning FBPO solid waste into liquid smoke will increase productivity by 18.18%. Implementation of Green Productivity can improve productivity through the improvement of FBPO waste treatment process which has been done by perfect combustion by pyrolysis process so that waste can be minimized to create environment industry POF clean and friendly environment.

  18. Knowledge production in education: Post-structuralism as epistemological potency

    Directory of Open Access Journals (Sweden)

    Sirley Lizott Tedeschi

    2017-09-01

    Full Text Available This paper aims to analyze the epistemological and methodological potentialities of Poststructuralism in education research. With a theoretical-bibliographic character, the research takes as main references Michel Foucault, Gilles Deleuze and Jacques Derrida’s contributions in order to problematize the modern metanarratives and the processes of knowledge production in this area. By problematizing modern metanarratives and pointing out the historical, contextual character, inherent in the process of knowledge production, this epistemological perspective has triggered a number of concerns, doubts and discontinuities that have reverberated in investigative processes in that area. Being open to this epistemological field may both contribute to the deconstruction of the conceptual apparatus of modernity, which has strongly marked the education research, and bring other epistemological and methodological possibilities for knowledge production in that area. In this sense, the potentiality of this epistemological and methodological perspective for research in education is the multiplicity of possibilities that it provides.

  19. Influence of menarche on the relation between diurnal cortisol production and ventral striatum activity during reward anticipation.

    Science.gov (United States)

    LeMoult, Joelle; Colich, Natalie L; Sherdell, Lindsey; Hamilton, J Paul; Gotlib, Ian H

    2015-09-01

    Adolescence is characterized by an increase in risk-taking and reward-seeking behaviors. In other populations, increased risk taking has been associated with tighter coupling between cortisol production and ventral striatum (VS) activation during reward anticipation; this relation has not yet been examined, however, as a function of adolescent development. This study examined the influence of pubertal development on the association between diurnal cortisol production and VS activity during reward anticipation. Pre- and post-menarcheal girls collected diurnal cortisol and completed an functional magnetic resonance imaging-based monetary incentive delay task, from which we extracted estimates of VS activity during the anticipation of reward, anticipation of loss and anticipation of non-incentive neutral trials. Post-menarcheal girls showed greater coupling between the cortisol awakening response and VS activation during anticipation of reward and loss than did their pre-menarcheal counterparts. Post-menarcheal girls did not differ from pre-menarcheal girls in their cortisol-VS coupling during anticipation of neutral trials, suggesting that puberty-related changes in cortisol-VS coupling are specific to affective stimuli. Interestingly, behavioral responses during the task indicate that post-menarcheal girls are faster to engage with affective stimuli than are pre-menarcheal girls. Thus, post-menarcheal girls exhibit neurobiological and behavioral patterns that have been associated with risk taking and that may underlie the dramatic increase in risk-taking behavior documented during adolescence. © The Author (2015). Published by Oxford University Press. For Permissions, please email: journals.permissions@oup.com.

  20. The use of sanitation products in milk and cheese production

    Directory of Open Access Journals (Sweden)

    Samir Kalit

    2001-06-01

    Full Text Available Considering hygienic conditions in cheese production the aim of thispaper was to investigate the influence of using some sanitation* products in milk and cheese production on family farms. This investigation was a part of the project “Improving the quality of Tounj cheese produced on family farms”. By use of the sanitation products, during milk production, significant (P<0.01 decrease of geometrical mean of total bacterial count from 3.54 x 105 to 8 x 103 in mL of milk, as well as significant (P<0.01 decrease of geometric mean of somatic cell count from 3.1 x 105 to 2.4 x 105 in mL of milk was observed. The ratio of hygienically unacceptable cheeses, according to the Regulations of microbial standards for foods (NN 46/94., significantly (P<0.01 decreased as well. Because of the new requests and standards, the sanitation products are more in use in both milk and cheese production on family farms. Investigated sanitation products were suitable for use in milk and Tounj cheese production.

  1. The importance of product definitions in US e-cigarette laws and regulations.

    Science.gov (United States)

    Lempert, Lauren K; Grana, Rachel; Glantz, Stanton A

    2016-04-01

    How electronic cigarettes and similar products (e-cigarettes) are defined affects how they are regulated, particularly whether existing laws for cigarettes apply, including sales and marketing, youth access, smoke-free and taxation laws. We examined the text of 46 bills that define e-cigarettes enacted in 40 states and characterised how e-cigarettes and similar products were defined. States enact laws creating new product categories for e-cigarettes separate from the 'tobacco product' category (eg, 'alternative nicotine product,' 'vapour product,' 'electronic nicotine device'), with four states explicitly excluding e-cigarettes from 'tobacco products.' Twenty-eight states do not include e-cigarettes in their definitions of 'tobacco products' or 'smoking,' eight include e-cigarettes as 'tobacco products,' three include e-cigarettes in 'smoking.' Sixteen states' definitions of e-cigarettes require nicotine, and five states pre-empt more stringent local laws. Tobacco and e-cigarette industry representatives tried to shape laws that benefit their interests. Definitions separating e-cigarettes from other tobacco products are common. Similar to past 'Trojan horse' policies, e-cigarette policies that initially appear to restrict sales (eg, limit youth access) may actually undermine regulation if they establish local pre-emption or create definitions that divide e-cigarettes from other tobacco products. Comparable issues are raised by the European Union Tobacco Products Directive and e-cigarette regulations in other countries. Policymakers should carefully draft legislation with definitions of e-cigarettes that broadly define the products, do not require nicotine or tobacco, do not pre-empt stronger regulations and explicitly include e-cigarettes in smoke-free and taxation laws. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/

  2. A Projection of Automated Book Production Control

    Directory of Open Access Journals (Sweden)

    Mario Barisic

    2006-12-01

    Full Text Available The paper elaborates on the recommendation of systematic introducing of XML technologies as a standard and integral factor in publishing and graphic business activities and as a further improvement of the existing PostScript graphic production platform. Procedures are proposed for applying norm setting in respect to production processes through related connections organized databases under XML technology in a hierarchical way, as well as a book production norm setting system. The proposal for work processes automation in the domain of printing business control is elaborated under the CIP4-JDF automating system. Operation results are used as guidelines for setting the elements of automated business operations in the book production domain, with integrated elements of new technologies, compatible with global trends.

  3. Pre-hospital identification and post-recovery challenges of intoxication with synthetic cannabinoid containing legal high products such as 'Exodus Damnation'.

    Science.gov (United States)

    Fitzpatrick, David; O'Meara, Patrick; Cunningham, Andrew

    2016-11-01

    This short report describes the case of a young adult male who had smoked a synthetic cannabinoid legal high product called 'Exodus Damnation'. The patient's presentation was atypical from that described in the literature, with hypotension and hypoxaemia. Of note was the rapid recovery after pre-hospital intervention with high-flow oxygen therapy and intravenous fluids. The patient refused on-going care, despite repeated advice to attend the Emergency Department. The distinct lack of specialist support and referral to drug treatment for this patient population, with whom ambulance services are coming into contact with increasing frequency, is reported. For those patients with the capacity to refuse on-going care, ambulance services may be in an opportune position to actively promote referral to support services for these vulnerable individuals. © The Author(s) 2016.

  4. Emulsified Water Products

    Directory of Open Access Journals (Sweden)

    Elif Tuğçe AKSUN

    2016-12-01

    Full Text Available Seafood is very important depending on having high protein rate and easily digestibility by human, for supply to an important part of animal protein needed. Determining the quality of emulsion-type products, emulsion stability, viscosity and gel strength properties are very important. In the production of products specified in this property emulsion; the main protein ratio and properties of raw material used while you; emulsion pH, temperature, ionic violence, mixing speed, type of fat and additives that are used as well. Previous studies show that particularly of products resulting from water emulsified chicken and goat meat emulsified product obtained from a high capacity of emulsified and compared to cattle and sheep meat is close to specifications, preparation of emulsified type products may be appropriate for the use of fish meat. Another quality parameter in the emulsified meat products, viscosity depends on the amount of meat used in direct proportion with the texture. Fish meat animals in connective tissue connective tissue in meat other butchers to rate ratio is quite low. In this respect, the fish meat produced using emulsified products viscosity according to products prepared using other meat products is quite low. Fish meat produced using emulsified fish sausage products based on surimi, sausage and fish pate fish varieties classed emulsion type products. In this review the different types of seafood using emulsified meat product.

  5. Designer-made meat and dairy products: Consumer-led product development

    DEFF Research Database (Denmark)

    Grunert, Klaus G.; Valli, Carlotta

    2001-01-01

    targeting these segments were derived and tested with consumers from these segments. Results show considerable potential for the development of food products which are differentiated in a consumer-based way. The paper closes with a step-model for consumer-led product development adapted to the current state...... of branding and differentiation in the product category.......Consumers differ in the kind of qualities they expect from food products, and they also differ in the way they infer quality from the product information available. Nevertheless, much product innovation in the food sector is still not geared towards specific consumer segments. This is especially...

  6. Designer made meat and dairy products: Consumer-led product development

    DEFF Research Database (Denmark)

    Grunert, Klaus G.; Valli, Carlotta

    targeting these segments were derived and tested with consumers from these segments. Results show considerable potential for the development of food products which are differentiated in a consumer-based way. The paper closes with a step-model for consumer-led product development adapted to the current state...... of branding and differentiation in the product category.......Consumers differ in the kind of qualities they expect from food products, and they also differ in the way they infer quality from the product information available. Nevertheless, much product innovation in the food sector is still not geared towards specific consumer segments. This is especially...

  7. Microwork and Virtual Production Networks in Sub-Saharan Africa ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Microwork and Virtual Production Networks in Sub-Saharan Africa and Southeast Asia ... content posted to social media sites; -categorizing products in online shops; or, ... that have realized that entry-level workers can be efficient and effective.

  8. Thermoregulation of Capsule Production by Streptococcus pyogenes

    Science.gov (United States)

    Kang, Song Ok; Wright, Jordan O.; Tesorero, Rafael A.; Lee, Hyunwoo; Beall, Bernard; Cho, Kyu Hong

    2012-01-01

    The capsule of Streptococcus pyogenes serves as an adhesin as well as an anti-phagocytic factor by binding to CD44 on keratinocytes of the pharyngeal mucosa and the skin, the main entry sites of the pathogen. We discovered that S. pyogenes HSC5 and MGAS315 strains are further thermoregulated for capsule production at a post-transcriptional level in addition to the transcriptional regulation by the CovRS two-component regulatory system. When the transcription of the hasABC capsular biosynthetic locus was de-repressed through mutation of the covRS system, the two strains, which have been used for pathogenesis studies in the laboratory, exhibited markedly increased capsule production at sub-body temperature. Employing transposon mutagenesis, we found that CvfA, a previously identified membrane-associated endoribonuclease, is required for the thermoregulation of capsule synthesis. The mutation of the cvfA gene conferred increased capsule production regardless of temperature. However, the amount of the capsule transcript was not changed by the mutation, indicating that a post-transcriptional regulator mediates between CvfA and thermoregulated capsule production. When we tested naturally occurring invasive mucoid strains, a high percentage (11/53, 21%) of the strains exhibited thermoregulated capsule production. As expected, the mucoid phenotype of these strains at sub-body temperature was due to mutations within the chromosomal covRS genes. Capsule thermoregulation that exhibits high capsule production at lower temperatures that occur on the skin or mucosal surface potentially confers better capability of adhesion and invasion when S. pyogenes penetrates the epithelial surface. PMID:22615992

  9. By-products from ethanol production - the forgotten part of the equation. Possibilities and challenges

    Energy Technology Data Exchange (ETDEWEB)

    Grinsted Jensen, H.; Bjoernsson, A.H.; Lind, K.M.

    2013-06-15

    Conventional bioethanol is produced from starch based feedstocks either via dry or wet milling, using typically maize or wheat. One by-product from bioethanol production is dried distiller's grain with solubles (DDGS), which has proven to be a valuable feed commodity for animal husbandry. Particularly, DDGS replaces expensive protein feed at a competitive price for farmers, which has hitherto led to a rapidly increasing market for distiller's grain with solubles in the US, who is by far the largest producer of grain-based bioethanol in the world. The US also exports DDGS since it has a long shelf-life and can therefore be shipped overseas. Exports of DDGS from the US are increasingly taking place with Asia but also Europe and South-America as international destinations. Studies indicate that the price of DDGS in the US follows the corn price and is roughly at the same price level, even though protein contents in distiller's grain with solubles are higher than for cereals. With this price relationship, feed diets incorporating DDGS produce cost savings for farmers. An example for a Danish dairy farm shows that with this price relationship profits would increase by around 5 % per dairy cow if DDGS is included in the fodder plan, accounting for roughly 10 % of the energy content. Given that the US exports large amounts of DDGS it would be expected that the price level in Denmark would be highly influenced by US export prices, if Danish farmers adopt DDGS in their feed rations. One major barrier for increased acceptance of DDGS by potential buyers/farmers is the absence of a standard for the product. Pre-tested and pre-blended food diets with DDGS could lead to greater certainty of effects and acceptance by farmers. This could presumably increase the price of DDGS from current levels, which is lower than the feed value appears to suggest, due to uncertainty around the product as well as varying quality of DDGS. When DDGS replaces traditional animal feed

  10. Effect of post-hatch transportation duration and parental age on broiler chicken quality, welfare, and productivity.

    Science.gov (United States)

    Jacobs, Leonie; Delezie, Evelyne; Duchateau, Luc; Goethals, Klara; Ampe, Bart; Lambrecht, Evelien; Gellynck, Xavier; Tuyttens, Frank A M

    2016-09-01

    Broiler chicks are transported to production sites within one to 2 d post-hatch. Possible effects of this transportation are poorly understood and could vary among chicks from breeder flocks of different ages. The aim of the present study was to investigate the effects of transportation duration and parental flock age on chick welfare, productivity, and quality. After hatch in a commercial hatchery, 1,620 mixed-sex chicks from 29-wk old (young) and 1,620 chicks from 60-wk old (old) breeders were subjected to transportation of 1.5 h or 11 h duration. After transportation, 2,800 chicks were divided among 100 pens, with each pen containing 28 chicks from one transportation crate (2 or 3 pens per crate). From the remaining chicks, on average 6 chicks (min 4, max 8) per crate (n = 228) were randomly selected and assessed for chick quality, weighed, and culled for yolk sac weighing (one d). Chicks that had not been assigned to pens or were not used for post-transportation measurements, were removed from the experiment (n = 212). Mortality, ADG, BW, and feed conversion ( FC: ) of the experimental chicks were recorded until 41 d. Meat quality was measured for breast fillets (n = 47). No interaction effect of parental age and transportation duration was found for any variables. BW and yolk sac weight at one d were lower for chicks transported 11 h than 1.5 h and for chicks from young versus old breeders. The effect of parental flock age on BW persisted until slaughter. Additionally, parental age positively affected ADG until slaughter. Chick quality was lower in chicks from old versus young breeders. Chick quality and productivity were not affected by transportation duration. Mortality and meat quality were not affected by either parental age or transportation duration. To conclude, no long-term detrimental effects were found from long post-hatch transportation in chicks from young or old parent flocks. Based on these results, we suggest that 11 h post

  11. Green product development : What does the country product space imply?

    NARCIS (Netherlands)

    Fraccascia, Luca; Giannoccaro, Ilaria; Albino, Vito

    This paper contributes to green product development by identifying the green products with the highest potential for growth in a country. To address our aim, we use the concept of product proximity and product space and, borrowing from the results of recent studies on complexity economics, we

  12. NONWOVEN TEXTILES WITH MEDICAL DESTINATION ROMANIAN PRODUCTION

    Directory of Open Access Journals (Sweden)

    BULACU Romulus

    2015-05-01

    Full Text Available The widest range of medical disposable from nonwoven textiles are: absorbent and hygiene products : (diapers, feminine care, incontinence from the layered structures absorbent or impervious; use products such as hospital operating theaters sterile clothing (caps, gowns, masks, shoe coverings, materials for field operators, lab coats, packaging materials for hot or cold treatments, sterile materials (wipes, bandages, sterile bandages, etc.. Currently these materials, in their majority, are imported. This paper presents research done for getting, with the country equipment, disposable medical products from 40 g/m2 nonwoven textile materials. The technology adopted for the purpose, in SC "Minet" S.A. Ramnicu Valcea, Romania consisted of the following steps:Carding - folding, the aggregate Spinnbau-Hergeth type, Germany, with major changes carding technology adjustment and folding, to obtain a fibrous layer with a mass per unit surface of about 40-50 g / m2 and a width of 2,1 m;Pre-heat consolidation by pre-heating required only to ensure product stability required minimal interphase transport to final consolidation. Final thermal consolidation of the fibrous layer by thermal calendering at a temperature of 110°C and calenders cylinder speed of 2 m / min. The processing of the fiber by carding - folding and preliminary thermally consolidation and final by calendering.

  13. Proactive Modeling of Market, Product and Production Architectures

    DEFF Research Database (Denmark)

    Mortensen, Niels Henrik; Hansen, Christian Lindschou; Hvam, Lars

    2011-01-01

    This paper presents an operational model that allows description of market, products and production architectures. The main feature of this model is the ability to describe both structural and functional aspect of architectures. The structural aspect is an answer to the question: What constitutes...... the architecture, e.g. standard designs, design units and interfaces? The functional aspect is an answer to the question: What is the behaviour or the architecture, what is it able to do, i.e. which products at which performance levels can be derived from the architecture? Among the most important benefits...... of this model is the explicit ability to describe what the architecture is prepared for, and what it is not prepared for - concerning development of future derivative products. The model has been applied in a large scale global product development project. Among the most important benefits is contribution to...

  14. Microbial hazards reduction during creamy cream cheese production

    Directory of Open Access Journals (Sweden)

    Dorota Miarka

    2015-03-01

    Full Text Available The purpose of the work was to identify the hazards relevant to the production of safe food and to assess the effects of a possible infection. The paper presents the microbiological hazards that can occur throughout the production of creamy cream cheese and indicates the means to their minimization or elimination. The analysis of microbiological hazards showed that in the manufacturing process of the type of cheese mentioned, there are a few critical steps that should be specifically overseen. In order to acquire a high quality product it is important to monitor a quality of raw material, the parameters of pasteurization and souring, temperature of product packaging, storage conditions of the finished product and maintain hygiene throughout the production. The process of heat treatment, which is pasteurization, is a critical step (critical control points - CCP for the whole process. Monitoring this stage and consistent adherence to Operational Pre-Condition Programs at the thermisation and centrifuging and later packaging, guarantees a safe product and its long shelf life.

  15. Heating, Ventilation, and Air Conditioning Design Strategy for a Hot-Humid Production Builder

    Energy Technology Data Exchange (ETDEWEB)

    Kerrigan, P. [Building Science Corporation, Somerville, MA (United States)

    2014-03-01

    Building Science Corporation (BSC) worked directly with the David Weekley Homes - Houston division to develop a cost-effective design for moving the HVAC system into conditioned space. In addition, BSC conducted energy analysis to calculate the most economical strategy for increasing the energy performance of future production houses in preparation for the upcoming code changes in 2015. This research project addressed the following questions: 1. What is the most cost effective, best performing and most easily replicable method of locating ducts inside conditioned space for a hot-humid production home builder that constructs one and two story single family detached residences? 2. What is a cost effective and practical method of achieving 50% source energy savings vs. the 2006 International Energy Conservation Code for a hot-humid production builder? 3. How accurate are the pre-construction whole house cost estimates compared to confirmed post construction actual cost?

  16. Bioethanol Production from Indigenous Algae

    Directory of Open Access Journals (Sweden)

    Madhuka Roy

    2015-02-01

    Full Text Available Enhanced rate of fossil fuel extraction is likely to deplete limited natural resources over short period of time. So search for alternative fuel is only the way to overcome this problem of upcoming energy crisis. In this aspect biofuel is a sustainable option. Agricultural lands cannot be compromised for biofuel production due to the requirement of food for the increasing population. Certain species of algae can produce ethanol during anaerobic fermentation and thus serve as a direct source for bioethanol production. The high content of complex carbohydrates entrapped in the cell wall of the microalgae makes it essential to incorporate a pre-treatment stage to release and convert these complex carbohydrates into simple sugars prior to the fermentation process. There have been researches on production of bioethanol from a particular species of algae, but this work was an attempt to produce bioethanol from easily available indigenous algae. Acid hydrolysis was carried out as pre-treatment. Gas Chromatographic analysis showed that 5 days’ fermentation by baker’s yeast had yielded 93% pure bioethanol. The fuel characterization of the bioethanol with respect to gasoline showed comparable and quite satisfactory results for its use as an alternative fuel.DOI: http://dx.doi.org/10.3126/ije.v4i1.12182International Journal of Environment Volume-4, Issue-1, Dec-Feb 2014/15, page: 112-120  

  17. Thermodynamic analysis of volatile organometallic fission products

    International Nuclear Information System (INIS)

    Auxier II, J.D.; Hall, H.L.; Cressy, Derek

    2016-01-01

    The ability to perform rapid separations in a post nuclear weapon detonation scenario is an important aspect of national security. In the past, separations of fission products have been performed using solvent extraction, precipitation, etc. The focus of this work is to explore the feasibility of using thermochromatography, a technique largely employed in superheavy element chemistry, to expedite the separation of fission products from fuel components. A series of fission product complexes were synthesized and the thermodynamic parameters were measured using TGA/DSC methods. Once measured, these parameters were used to predict their retention times using thermochromatography. (author)

  18. Developing and promoting OKP production system: a JIT production planning approach

    Science.gov (United States)

    Samavati, Mehran

    2011-10-01

    The role of production in competitive system of market on one hand and the changing conditions of market on the other hand has caused the need for more developed planning in such environments. The general purpose of the present research is to realize One-of- a- Kind- Product model (OKP) that is developed in two stages. In OKP model presented in 1994 only one sample of each product is produced and only one production method is considered for each product. In order to make OKP model more real and to use it in promoting more production methods, the following developments were made in this research: 1-First Development: Considering various methods for producing each product. 2-Second Development: Producing more than one sample of each product, while considering various production methods for each product. These models promoted OKP model of 1994. They can be used in more diversified production methods in order to promote them. In present model, while describing the main OKP model new models are provided as well. The significance of OKP has been described in Introduction

  19. Estimating product-to-product variations in metal forming using force measurements

    Science.gov (United States)

    Havinga, Jos; van den Boogaard, Ton

    2017-10-01

    The limits of production accuracy of metal forming processes can be stretched by the development of control systems for compensation of product-to-product variations. Such systems require the use of measurements from each semi-finished product. These measurements must be used to estimate the final quality of each product. We propose to predict part of the product-to-product variations in multi-stage forming processes based on force measurements from previous process stages. The reasoning is that final product properties as well as process forces are expected to be correlated since they are both affected by material and process variation. In this study, an approach to construct a moving window process model based on historical data from the process is presented. These regression models can be built and updated in real-time during production. The approach is tested with data from a demonstrator process with cutting, deep drawing and bending stages. It is shown that part of the product-to-product variations in the process can be predicted with the developed process model.

  20. Biocidal Products and Borderline Products

    OpenAIRE

    Yılmaz, Abdullah

    2015-01-01

    Biocidal product is defined as preparations sold in ready form to use that contains one or more active substances and has control effect, movement restriction or destruction against harmful organisms which has harmful effect on products that people use or produce or animals or environment. These substances which are composed mostly chemicals and ease our lifes are used in increasingly every areas of our life on the other hand they carry variety of risks and threaten our lives. In terms of env...

  1. Product quality of parenteral vancomycin products in the United States.

    Science.gov (United States)

    Nambiar, S; Madurawe, R D; Zuk, S M; Khan, S R; Ellison, C D; Faustino, P J; Mans, D J; Trehy, M L; Hadwiger, M E; Boyne, M T; Biswas, K; Cox, E M

    2012-06-01

    In response to concerns raised about the quality of parenteral vancomycin products, the U.S. Food and Drug Administration (FDA) is investigating the product quality of all FDA-approved parenteral vancomycin products available in the United States. Product quality was evaluated independently at two FDA Office of Testing and Research (FDA-OTR) sites. In the next phase of the investigation, being done in collaboration with the National Institute of Allergy and Infectious Diseases, the in vivo activity of these products will be evaluated in an appropriate animal model. This paper summarizes results of the FDA investigation completed thus far. One site used a validated ultrahigh-pressure liquid chromatography method (OTR-UPLC), and the second site used the high-performance liquid chromatography (HPLC) method for related substances provided in the British Pharmacopeia (BP) monograph for vancomycin intravenous infusion. Similar results were obtained by the two FDA-OTR laboratories using two different analytical methods. The products tested had 90 to 95% vancomycin B (active component of vancomycin) by the BP-HPLC method and 89 to 94% vancomycin by OTR-UPLC methods. Total impurities were 5 to 10% by BP-HPLC and 6 to 11% by OTR-UPLC methods. No single impurity was >2.0%, and the CDP-1 level was ≤ 2.0% across all products. Some variability in impurity profiles of the various products was observed. No adverse product quality issues were identified with the six U.S. vancomycin parenteral products. The quality parameters of all parenteral vancomycin products tested surpassed the United States Pharmacopeia acceptance criteria. Additional testing will characterize in vivo performance characteristics of these products.

  2. SaferProducts API

    Data.gov (United States)

    US Consumer Product Safety Commission — On March 11, 2011, the U.S. Consumer Product Safety Commission launched SaferProducts.gov. This site hosts the agency's new Publicly Available Consumer Product...

  3. Innovation in Product Development

    DEFF Research Database (Denmark)

    McAloone, Tim C.; Restrepo-Giraldo, John Dairo

    2005-01-01

    The course on Innovation in Product Development attempts to identify and understand the nature of innovation and product development and their important factors. The course takes both a theoretical and a practical approach and employs a mix of lectures, project work and group discussion. Format...... insight. Course content The following aspects of innovation in product development are considered: - Humans and products - Needs and products - Product life - Teams creating products - Products creating business - Product development models - Organising product development - Product development tools...... - The future of product development....

  4. Lot-sizing for a single-stage single-product production system with rework of perishable production defectives

    NARCIS (Netherlands)

    Teunter, R.; Flapper, S.D.P.

    2003-01-01

    We consider a single-stage single-product production system. Produced units may be non-defective, reworkable defective, or non-reworkable defective. The system switches between production and rework. After producing a fixed number (N) of units, all reworkable defective units are reworked. Reworkable

  5. Product Stigmaticity : Understanding, Measuring and Managing Product-Related Stigma

    NARCIS (Netherlands)

    Vaes, K.

    2014-01-01

    Stigma-free Product Design. Many of the products intended to relieve us from discomforting or unsafe situations and many medical and assistive devices are experienced as unpleasant and uncomfortable. On top of their discomfort, product users may also experience social unease from the people around

  6. The production of direct object clitics in pre-school- and primary school-aged children with specific language impairments.

    Science.gov (United States)

    Guasti, Maria Teresa; Palma, Silvia; Genovese, Elisabetta; Stagi, Paolo; Saladini, Gabriella; Arosio, Fabrizio

    2016-01-01

    Third-person direct object (DO) clitic pronoun production is examined through an elicited production method in pre-school- and primary school-aged groups of Italian children with specific language impairment (SLI) to establish whether there is an improvement from age 5 years to age 7 years and whether there are qualitative differences in the two groups' responses. It was found that 5- and 7-year-old Italian children with SLI produce fewer third-person DO clitics than same-age peers. The kind of responses they provide changes: at 5 years, children with SLI tend to omit clitics, while at 7 years, they use a full noun. Production of third-person DO clitics is a persistent challenge for children with SLI and is confirmed to be a good clinical marker both at 5 and 7 years of age.

  7. Optimizing the order processing of customized products using product configuration

    DEFF Research Database (Denmark)

    Hvam, Lars; Bonev, Martin; Denkena, B.

    2011-01-01

    . Product configuration based on integrated modular product structure and product family architecture has been recognized as an effective means for implementing mass customization. In order to evaluate the effects of product configuration on order processing, a study has been conducted by the Department...... and its benefits for the order processing have been evaluated....

  8. THE EFFECTS OF CROSS-BORDER BANK MERGERS AND ACQUISITIONS ON THE PRODUCTIVITY OF CREDIT INSTITUTIONS

    Directory of Open Access Journals (Sweden)

    Andreea N. POPOVICI

    2014-06-01

    Full Text Available The purpose of the current research is to study bank mergers and acquisitions (M-A and to see whether they have implications on the productivity of the target banks, and also for the bidder bank. The aim of this paper is to see if, during 2002-2008 period, three banks from the European banking system, Banca Comerciala Romana from Romania, Slovenskásporiteľňa from Slovakia and Erste Bank Group from Austria improved their productivity due to the fact that all of them were involved in a process of cross-border merger or acquisitions, even if the bank is the purchaser or the target. To reach our goal, we used DEA method, by estimating the productivity achieved by these three banks during the period pre-M-A, post M-A, but we also estimated the productivity for entire period of seven years. Using Malquist DEA method, we show that, on average, the merger or acquisition in which a bank was involved improved the Total Factor Productivity of all analyzed banks.

  9. Fickle product mix: Exporters adapting their product vectors across markets

    OpenAIRE

    Fontagné, Lionel; Secchi, Angelo; Tomasi, Chiara

    2014-01-01

    This paper analyzes how multi-product firms adjust their exported product-mix across desti- nations. Using cross sections of Italian and French data, we show that firms do not follow a rigid ordering in their product mix exported in different markets but rather they adapt their choices to better match with country characteristics. By using metrics based on export shares and on sequences of product names we provide new insights on the extent a firm's products portfolio changes across destinati...

  10. WHAT IS BEHIND BIASED TECHNICAL CHANGE IN PRODUCTION OF CEREAL AND OILSEED CROPS IN SLOVAKIA?

    Directory of Open Access Journals (Sweden)

    Peter FANDEL

    2014-11-01

    Full Text Available This study investigates the productivity change in the production of cereal and oilseed crops in Slovakia with special emphasis on technical change analysis. It employs a non-parametric distance function approach to measure Malmquist productivity index which is decomposed into technical efficiency change and technical change. Technical change is further decomposed into technical change magnitude and input- and output-bias indices. The productivity change components provide more detailed information about character of productivity change itself and its sources. Our results indicate that productivity in the analysed sector decreased approximately by 20% within the examined period of 1998-2007. The decrease was caused mostly by worsening the technical change (-41,6%. Indices of input- and output bias of technical change were various from unity what suggests that technical change was not Hicks’- neutral. Results of further analysis of the direction of technical change bias indicate that farms in average tend to apply fertilizers-using/seed-saving, seed-using/labour-saving, and fertilizers-using/labour-saving technical change bias over the whole sample period, as well as in the EU pre-accession and EU post-accession periods.

  11. [Service productivity in hospital nursing--conceptual framework of a productivity analysis].

    Science.gov (United States)

    Thomas, D; Borchert, M; Brockhaus, N; Jäschke, L; Schmitz, G; Wasem, J

    2015-01-01

    Decreasing staff numbers compounded by an increasing number of cases is regarded as main challenge in German hospital nursing. These input reductions accompanied by output extensions imply that hospital nursing services have had to achieve a continuous productivity growth in the recent years. Appropriately targeted productivity enhancements require approved and effective methods for productivity acquisition and measurement. However, there is a lack of suitable productivity measurement instruments for hospital nursing services. This deficit is addressed in the present study by the development of an integrated productivity model for hospital nursing services. Conceptually, qualitative as well as quantitative aspects of nursing services productivity are equally taken into consideration. Based on systematic literature reviews different conceptual frameworks of service productivity and the current state of research in hospital nursing services productivity were analysed. On this basis nursing sensitive inputs, processes and outputs were identified and integrated into a productivity model. As an adequate framework for a hospital nursing services productivity model the conceptual approach by Grönroos/Ojasalo was identified. The basic structure of this model was adapted stepwise to our study purpose by integrating theoretical and empirical findings from the research fields of service productivity, nursing productivity as well as national and international nursing research. Special challenges existed concerning the identification of relevant influencing factors as well as the representation of nursing sensitive outputs. The final result is an integrated productivity model, which can be used as an adequate framework for further research in hospital nursing productivity. Research on hospital nursing services productivity is rare, especially in Germany. The conceptual framework developed in this study builds on established knowledge in service productivity research. The

  12. Applying environmental product design to biomedical products research.

    Science.gov (United States)

    Messelbeck, J; Sutherland, L

    2000-12-01

    The principal themes for the Biomedical Research and the Environment Conference Committee on Environmental Economics in Biomedical Research include the following: healthcare delivery companies and biomedical research organizations, both nonprofit and for-profit, need to improve their environmental performance; suppliers of healthcare products will be called upon to support this need; and improving the environmental profile of healthcare products begins in research and development (R&D). The committee report begins with requirements from regulatory authorities (e.g., U.S. Environmental Protection Agency [EPA], the U.S. Food and Drug Administration), and the healthcare delivery sector). The 1998 American Hospital Association and EPA Memorandum of Understanding to reduce solid waste and mercury from healthcare facilities is emblematic of these requirements. The dominant message from the requirements discussion is to ensure that R&D organizations do not ignore customer, environmental, and regulatory requirements in the early stages of product development. Several representatives from healthcare products manufacturers presented their companies' approaches to meeting these requirements. They reported on efforts to ensure that their R&D processes are sensitive to the environmental consequences from manufacturing, distributing, using, and disposing of healthcare products. These reports describe representatives' awareness of requirements and the unique approaches their R&D organizations have taken to meet these requirements. All representatives reported that their R&D organizations have embraced environmental product design because it avoids the potential of returning products to R&D to improve the environmental profile. Additionally, several reports detailed cost savings, sustainability benefits, and improvements in environmental manufacturing or redesign, and increased customer satisfaction. Many companies in healthcare delivery are working to improve environmental

  13. Nutrient intakes among children and adolescents eating usual pizza products in school lunch compared with pizza meeting HealthierUS School Challenge criteria.

    Science.gov (United States)

    Hur, In Young; Marquart, Len; Reicks, Marla

    2014-05-01

    Pizza is a popular food that can contribute to high intakes of saturated fat and sodium among children and adolescents. The objective of this study was to compare daily nutrient intakes when a pizza product meeting the US Department of Agriculture's criteria for competitive food entrées under the HealthierUS School Challenge (HUSSC) was substituted for usual pizza products consumed during foodservice-prepared school lunch. The study used National Health and Nutrition Examination Survey (2005-2008) dietary recall data from a cross-sectional sample of US children and adolescents (age 5 to 18 years, n=337) who ate pizza during school lunch on 1 day of dietary recall. Daily nutrient intakes based on the consumption of usual pizza products for school lunch (pre-modeled) were compared with intakes modeled by substituting nutrient values from an HUSSC whole-grain pizza product (post-modeled). Paired t tests were used to make the comparison. Post-modeled intakes were lower in daily energy, carbohydrate, total fat, saturated fat, cholesterol, and sodium compared with pre-modeled intakes among children and adolescents (Ppizza product for usual pizza products may significantly improve dietary quality of children and adolescents eating pizza for school lunch, indicating that it could be an effective approach to improve the nutritional quality of school lunch programs. Copyright © 2014 Academy of Nutrition and Dietetics. Published by Elsevier Inc. All rights reserved.

  14. Preparing for Automated Derivation of Products in a Software Product Line

    National Research Council Canada - National Science Library

    McGregor, John D

    2005-01-01

    ... to bring a product to market, or through other production improvements. Business goals such as these make automated product derivation an appealing strategy to a software product line organization...

  15. Radioactivity distribution in phosphate products, by-products, effluents, and wastes

    International Nuclear Information System (INIS)

    Guimond, R.J.; Windham, S.T.

    1975-08-01

    Phosphate rock throughout the world contains uranium in concentrations ranging from a few ppM to a few hundred ppM. In the United States, phosphate rock normally contains between 100 to 150 ppM uranium. Mining and processing of these ores redistributes much of the uranium daughters among the various products, by-products, and wastes. These materials are then widely dispersed throughout the environment. This redistribution may lead to increased exposure of the public to these naturally-occurring radionuclides. In determining the magnitude of the population exposure caused by this redistribution and in developing environmental standards and controls to prevent contamination of the biosphere from these naturally-occurring radionuclides it is necessary to determine the concentrations and total quantities of these radionuclides in the products, by-products, effluents and wastes of phosphate mining and manufacturing. Samples of phosphate ores, products, by-products, effluents, and wastes were obtained and analyzed for their radioactivity content. Quantities of radioactivity entering the environment through various products, by-products, effluents, and wastes were estimated

  16. Saccharification of Sugarcane Bagasse by Enzymatic Treatment for bioethanol production

    Directory of Open Access Journals (Sweden)

    Ahmed, F. M.

    2012-06-01

    Full Text Available Aims: The escalating demands for traditional fossil fuels with unsecured deliverance and issues of climate change compel the researchers to develop alternative fuels like bioethanol. This study examines the prospect of biofuel production from high carbohydrate containing lignocellulosic material, e.g. sugarcane bagasse through biological means. Methodology and Results: Cellulolytic enzymes were collected from the culture filtrate of thermotolerant Trichodermaviride grown on variously pre-treated sugarcane bagasse. CMCase and FPase enzyme activities were determined as a measure of suitable substrate pre-treatment and optimum condition for cellulolytic enzyme production. The highest CMCase and FPase activity was found to be 1.217 U/ml and 0.109 U/ml respectively under the production conditions of 200 rpm, pH 4.0 and 50 °C using steamed NaOH treated bagasse as substrate. SEM was carried out to compare and confirm the activity of cellulolytic enzymes on sugarcane bagasse. Saccharification of pre-treated bagasse was carried out with crude enzymes together using a two-factor experimental design. Under optimized conditions the pre-treated bagasse was saccharified up to 42.7 % in 24 h. The hydrolysate was concentrated by heating to suitable concentration and then used for fermentation by an indigenous isolate of Saccharomyces cerevisiae. With 50 and 80 % brix containing liquor the concentration of alcohol was 0.579 % and 1.15 % respectively. Conclusion, significance and impact of study: This is the first report in Bangladesh for the production of cellulosicethanol using local isolates. Though the rate of alcohol production was very low, a great impetus in this field can maximize the production thereby meet the demand for fuel in future.

  17. The Impacts of Country-of-origin, Product Involvement, and Product Familiarity on Product Evaluation

    OpenAIRE

    Nugroho, Sahid Susilo; Rostiani, Rokhima; Gitosudarmo, Indriyo

    2014-01-01

    One of the most interesting phenomena in global business is the existence of a product’scountry-of-origin (COO). COO as an informational cue has been proven to affect consumer’spurchasing decisions in terms of their perception towards the product’s attributes as well astheir overall evaluation of the product. The objective of this study is to investigate the impacts ofcountry-of-origin on product evaluation in the Indonesian market by considering consumers’product familiarity and consumers’ p...

  18. Optimized production of vanillin from green vanilla pods by enzyme-assisted extraction combined with pre-freezing and thawing.

    Science.gov (United States)

    Zhang, Yanjun; Mo, Limei; Chen, Feng; Lu, Minquan; Dong, Wenjiang; Wang, Qinghuang; Xu, Fei; Gu, Fenglin

    2014-02-19

    Production of vanillin from natural green vanilla pods was carried out by enzyme-assisted extraction combined with pre-freezing and thawing. In the first step the green vanilla pods were pre-frozen and then thawed to destroy cellular compartmentation. In the second step pectinase from Aspergillus niger was used to hydrolyze the pectin between the glucovanillin substrate and β-glucosidase. Four main variables, including enzyme amount, reaction temperature, time and pH, which were of significance for the vanillin content were studied and a central composite design (CCD) based on the results of a single-factor tests was used. Response surface methodology based on CCD was employed to optimize the combination of enzyme amount, reaction temperature, time, and pH for maximum vanillin production. This resulted in the optimal condition in regards of the enzyme amount, reaction temperature, time, and pH at 84.2 mg, 49.5 °C, 7.1 h, and 4.2, respectively. Under the optimal condition, the experimental yield of vanillin was 4.63% ± 0.11% (dwb), which was in good agreement with the value predicted by the model. Compared to the traditional curing process (1.98%) and viscozyme extract (2.36%), the optimized method for the vanillin production significantly increased the yield by 133.85% and 96%, respectively.

  19. Comparison of Authorization/Registration/Notification Processes among Biocidal Products, Cosmetics, Plant Protection Products and Human Medicinal Products

    OpenAIRE

    Söyleriz, Yüksel

    2015-01-01

    In this study, comparison of the authorization/registration/notification processes of biocidal products, cosmetics, plant protection products and medicinal products are made and in this respect, the situation in EU is assessed.

  20. Productivity analysis of sunflower production in Turkey

    International Nuclear Information System (INIS)

    Semerci, A.

    2012-01-01

    In Turkey, which ranks the tenth country worldwide in the sunflower (Helianthus annuus L.) production, 55% of the production is carried out in Thrace Region. Therefore, agricultural enterprises in Thrace Region, situated in the European part of Turkey have specialized in producing sunflower, and have become the centre of vegetable oil industry in the region in terms of produced raw material. This research was conducted in 182 agricultural enterprises in 3 provinces of Thrace Region in Turkey and its objective was to determine input/output relations in sunflower production. The study indicates that the determination coefficient (r/sup 2/) derived from Cobb-Douglas production function was significant at 0.01 level and the elasticity coefficients of the variables (except chemical fertilizer) were found beta i positive in derived equation. It was determined that the variable of herbicide cost had the highest value of the marginal effectiveness coefficients and none of the variables was used at economically optimal level in the study area. When the Marginal Technical Substitution and the Price Rates were taken into consideration, it was noted that only the seed cost/hoeing cost was closest to economically optimum level (1.10). According to stepwise analysis the Land Renting Value was determined as the most important variable in sunflower production. (author)

  1. Post Processing Methods used to Improve Surface Finish of Products which are Manufactured by Additive Manufacturing Technologies: A Review

    Science.gov (United States)

    Kumbhar, N. N.; Mulay, A. V.

    2016-08-01

    The Additive Manufacturing (AM) processes open the possibility to go directly from Computer-Aided Design (CAD) to a physical prototype. These prototypes are used as test models before it is finalized as well as sometimes as a final product. Additive Manufacturing has many advantages over the traditional process used to develop a product such as allowing early customer involvement in product development, complex shape generation and also save time as well as money. Additive manufacturing also possess some special challenges that are usually worth overcoming such as Poor Surface quality, Physical Properties and use of specific raw material for manufacturing. To improve the surface quality several attempts had been made by controlling various process parameters of Additive manufacturing and also applying different post processing techniques on components manufactured by Additive manufacturing. The main objective of this work is to document an extensive literature review in the general area of post processing techniques which are used in Additive manufacturing.

  2. Productive and Re-Productive Thinking in Solving Insight Problems

    Science.gov (United States)

    Cunningham, J. Barton; MacGregor, James N.

    2014-01-01

    Many innovations in organizations result when people discover insightful solutions to problems. Insightful problem-solving was considered by Gestalt psychologists to be associated with productive, as opposed to re-productive, thinking. Productive thinking is characterized by shifts in perspective which allow the problem solver to consider new,…

  3. BRAND - PRODUCT INTERDEPENDENCE

    Directory of Open Access Journals (Sweden)

    Tudor NISTORESCU

    2014-06-01

    Full Text Available In this paper we conceptually discussed the brands’ role in the society, the dimensions of branding and the relationship between the brand and the products. We adhere to the main ideas expressed in the literature, that the brand is more than a product. However the product is needed to render the brand tangible. The product is the magic box that delivers the brand experience. Without the product, the brand meaning would have difficulties in attracting customers. More studies are needed to investigate the brand-product relationship.

  4. Defining Product Intake Fraction to Quantify and Compare Exposure to Consumer Products.

    Science.gov (United States)

    Jolliet, Olivier; Ernstoff, Alexi S; Csiszar, Susan A; Fantke, Peter

    2015-08-04

    There is a growing consciousness that exposure studies need to better cover near-field exposure associated with products use. To consistently and quantitatively compare human exposure to chemicals in consumer products, we introduce the concept of product intake fraction, as the fraction of a chemical within a product that is eventually taken in by the human population. This metric enables consistent comparison of exposures during consumer product use for different product-chemical combinations, exposure duration, exposure routes and pathways and for other life cycle stages. We present example applications of the product intake fraction concept, for two chemicals in two personal care products and two chemicals encapsulated in two articles, showing how intakes of these chemicals can primarily occur during product use. We demonstrate the utility of the product intake fraction and its application modalities within life cycle assessment and risk assessment contexts. The product intake fraction helps to provide a clear interface between the life cycle inventory and impact assessment phases, to identify best suited sentinel products and to calculate overall exposure to chemicals in consumer products, or back-calculate maximum allowable concentrations of substances inside products.

  5. EPD--environmental product declarations for wood products : an application of life cycle information about forest products

    Science.gov (United States)

    Richard Bergman; Adam Taylor

    2011-01-01

    Transparent and credible environmental labeling of products is vital for a sustainable future. Ecolabeling shows information on the environmental performance of products, processes, and services. This article focuses on one type of ecolabeling referred to as environmental product declarations (EPDs) that provide environmental impact information based on life cycle...

  6. Bioactive Compounds of Blueberries: Post-Harvest Factors Influencing the Nutritional Value of Products.

    Science.gov (United States)

    Michalska, Anna; Łysiak, Grzegorz

    2015-08-10

    Blueberries, besides having commonly-recognized taste properties, are also a valuable source of health-promoting bioactive compounds. For several decades, blueberries have gained in popularity all over the world, and recent years have seen not only an increase in fresh consumption, but also in the importance of blueberries for the processing industry. Blueberry processing mostly consists of freezing and juicing. Recently, more attention has been drawn to dewatering and drying, which are promising areas for developing novel blueberry products. Processing affects each biologically-active compound in a different way, and it is still unknown what changes those compounds undergo at the molecular level after the application of different processing technologies. This work presents the most recent state of knowledge about the pre-treatment and processing methods applied to blueberries and their influence on the content of biologically-active compounds. The presentation of methods is preceded by a brief overview of the characteristics of the blueberry species, a description of the chemical composition of the fruit and a short note about the main growing areas, production volumes and the management of fruit crops.

  7. Forms and Factors of Animal Products Marketing in the early post-Meiji Years

    OpenAIRE

    Ono, Seishi

    1982-01-01

    As far as the period after the Meiji era is concerned, at its begining marketing of animal products was formed in conlpliance with the properties of products as a public commodity and the amount of investment needed. The former factor depends basically on the divisibility and the preservation possibilities of the products. The latter is the capital needed for marketing and production. 1) Eggs are the most divisible and preservable of all the animal products. Also, hens can be kept with sm...

  8. Final report of the pre - investigation phase. Project on the establishment and renovation of renewable energy production facilities in Northern Poland

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-07-01

    The project for the erection of a windmill park and the renovation/modernisation of the hydro power plants reached with the finishing of the pre-investigation a milestone. The results of the investigations show that the project is fully corresponding with both EU and polish politic aims of increased utilisation of renewable energy sources for electricity production. Further the pre-investigation notified, that in Poland there exists a lack of experience of the utilisation of wind for electricity production, as there exists only 12 windmill/windmill parks, so that the project is evaluated to have a high demonstration effect on the production of renewable energy based on wind. During the pre-investigation there were elaborated among others feasibility studies on the erection of the windmill park and the renovation of the hydro power plants. The economic feasibility calculations on both parts of the project, found that erection of the windmill park and the renovation of the hydro power plants are fully feasible under the existing conditions. It is foreseen that KEW, the local electricity production company as investor will obtain a loan under the Danish environmental soft loan program for Eastern Europe for the equipment and installation of the equipment. Associated specialist work is applied for support by the Danish Environmental Agency and the Danish Energy Agency. That these institutions and the Danish State Export Credit Agency (EKF) approve their principal willingness to support this project is the next necessary step for the projects implementation. (au)

  9. EFFECT OF SHEARING DURING PREGNANCY ON PRODUCTIVE PERFORMANCE IN THE POST-PARTUM PERIOD OF EWES ON EXTENSIVE HUSBANDRY

    Directory of Open Access Journals (Sweden)

    Viviane Marques Guyoti

    2015-04-01

    Full Text Available The use of shearing during pregnancy has been described as a tool for improving productivity in sheep and for minimizing perinatal mortality in lambs through the increase of fetal development. This study assessed the effect of shearing around 74 days of gestation on the productive performance of ewes and lambs during the first month of life. Forty Corriedale ewes were inseminated in autumn in Southern Brazil. All ewes were kept together at the same pasture under extensive husbandry conditions. The ewes were randomly separated into two treatment groups: twenty animals were completely sheared at 74 ± 6 days of pregnancy, and twenty were kept without sheared during pregnancy, composing the control group. Ewes and their lambs were evaluated at three different times during the experiment: at birth, between 15 and 21 days post-partum and between 22 and 45 days post-partum. Ewes had their body condition score, body weight, placental weight, milk production and serum concentrations of beta-hydroxybutyrate measured, while lambs had hematocrit, hemoglobin, and plasma lactate and glucose, as well as body weight at birth and until wean determined. Values of hematocrit and hemoglobin were lower and body weight at birth and at wean was higher in the group of lambs born from sheared ewes. Placenta weight was higher in sheared ewes. Body condition score and beta-hydroxybutyrate showed no differences between groups. Milk production of sheared ewes (1.26 L/day was higher than in control group (0.93 L/day. Shearing ewes at 74 days of pregnancy was efficient for the better development of lambs at post-birth, reducing perinatal mortality rates.

  10. An Optimization Model for Product Placement on Product Listing Pages

    Directory of Open Access Journals (Sweden)

    Yan-Kwang Chen

    2014-01-01

    Full Text Available The design of product listing pages is a key component of Website design because it has significant influence on the sales volume on a Website. This study focuses on product placement in designing product listing pages. Product placement concerns how venders of online stores place their products over the product listing pages for maximization of profit. This problem is very similar to the offline shelf management problem. Since product information sources on a Web page are typically communicated through the text and image, visual stimuli such as color, shape, size, and spatial arrangement often have an effect on the visual attention of online shoppers and, in turn, influence their eventual purchase decisions. In view of the above, this study synthesizes the visual attention literature and theory of shelf-space allocation to develop a mathematical programming model with genetic algorithms for finding optimal solutions to the focused issue. The validity of the model is illustrated with example problems.

  11. The Effects of Pre-Task Planning and On-line Planning on Fluency, Complexity, and Accuracy in L2 Monologic Oral Production.

    Science.gov (United States)

    Yuan, Fangyuan; Ellis, Rod

    2003-01-01

    Investigated the effects of both pre-task and on-line planning on second language (L2) oral production. Results show that pre-task planning enhances grammatical complexity while on-line planning positively influences accuracy and grammatical complexity. Pre-task planners also produced more fluent and lexically varied language than the on-line…

  12. Radioisotope production

    International Nuclear Information System (INIS)

    1988-01-01

    The trial production runs started in the previous report period were continued and have been extended to 67 Ga, 81 Rb/ 81m Kr and 111 In, the production of which will be taken over from the Pretoria cyclotron at the end of this year, when that machine is scheduled to be shut down. After commissioning of the target water cooling system and the helium cooling system for beam foil windows at the beginning of this year, these production runs could also be extended to high beam currents (up to 50 μA). Test consignments of a number of products have been supplied to various potential future users, and 123 I, in the form of Na 123 I capsules as well as 123 I-sodium hippurate, and 52 Fe-citrate have actually been used with success in trial diagnostic studies on patients. A procedure for labelling IPPA and 3-IPMPA with 123 I has been developed, while initial work has also been done on the radioiodination of monoclonal antifibrine antibodies. The last major facility needed for the commencement of the routine radioisotope production programme, namely the multiple-target facility, is now ready for installation in the production vault within the next few weeks, and routine production runs are expected to start in November 1988. 4 figs., 18 refs

  13. Applying linear programming model to aggregate production planning of coated peanut products

    Science.gov (United States)

    Rohmah, W. G.; Purwaningsih, I.; Santoso, EF S. M.

    2018-03-01

    The aim of this study was to set the overall production level for each grade of coated peanut product to meet market demands with a minimum production cost. The linear programming model was applied in this study. The proposed model was used to minimize the total production cost based on the limited demand of coated peanuts. The demand values applied to the method was previously forecasted using time series method and production capacity aimed to plan the aggregate production for the next 6 month period. The results indicated that the production planning using the proposed model has resulted a better fitted pattern to the customer demands compared to that of the company policy. The production capacity of product family A, B, and C was relatively stable for the first 3 months of the planning periods, then began to fluctuate over the next 3 months. While, the production capacity of product family D and E was fluctuated over the 6-month planning periods, with the values in the range of 10,864 - 32,580 kg and 255 – 5,069 kg, respectively. The total production cost for all products was 27.06% lower than the production cost calculated using the company’s policy-based method.

  14. Efficiency and Import Penetrationon the Productivity of Textile Industry and Textile Products

    Directory of Open Access Journals (Sweden)

    Catur Basuki Rakhmawan

    2012-12-01

    Full Text Available Although textile industry and textile products belong to the strategic sub-sector of manufacturing industry in Indonesia, they are facing problems on the availability of energy, old production machines, and the flooding of imported products into the domestic market. This study is aimed to analyze the efficiency and productivity as performance indicators and how the efficiency and import penetration affect the productivity of textile industry and textile products. The methods of data analysis used in this research are divided in two phases. The first phase, the non-metric approach of Data Envelopment Analysis (DEA is applied to measure the efficiency and productivity. Secondly, the fixed effect model of econometric regression approach is used to find out the effects of efficiency and import penetration on the productivity of textile industry and textile products. The result shows that the ave-rage level of efficiency of textile industry and textile products during the period of 2004 – 2008 is about 40 percent with a growth rate of average productivity increases 2.4 percent. Whereas, the econometric estimation results indicate that the increase of efficiency will positively and significantly affect the productivity of textile industry and textile products. On the other hand, the increase of import penetration will negatively affect the productivity of this industry.

  15. Direct and Indirect Effects of Behavioral Parent Training on Infant Language Production.

    Science.gov (United States)

    Bagner, Daniel M; Garcia, Dainelys; Hill, Ryan

    2016-03-01

    Given the strong association between early behavior problems and language impairment, we examined the effect of a brief home-based adaptation of Parent-child Interaction Therapy on infant language production. Sixty infants (55% male; mean age 13.47±1.31 months) were recruited at a large urban primary care clinic and were included if their scores exceeded the 75th percentile on a brief screener of early behavior problems. Families were randomly assigned to receive the home-based parenting intervention or standard pediatric primary care. The observed number of infant total (i.e., token) and different (i.e., type) utterances spoken during an observation of an infant-led play and a parent-report measure of infant externalizing behavior problems were examined at pre- and post-intervention and at 3- and 6-month follow-ups. Infants receiving the intervention demonstrated a significantly higher number of observed different and total utterances at the 6-month follow-up compared to infants in standard care. Furthermore, there was an indirect effect of the intervention on infant language production, such that the intervention led to decreases in infant externalizing behavior problems from pre- to post-intervention, which, in turn, led to increases in infant different utterances at the 3- and 6-month follow-ups and total utterances at the 6-month follow-up. Results provide initial evidence for the effect of this brief and home-based intervention on infant language production, including the indirect effect of the intervention on infant language through improvements in infant behavior, highlighting the importance of targeting behavior problems in early intervention. Copyright © 2015. Published by Elsevier Ltd.

  16. One-carbon substrate-based biohydrogen production: microbes, mechanism, and productivity.

    Science.gov (United States)

    Rittmann, Simon K-M R; Lee, Hyun Sook; Lim, Jae Kyu; Kim, Tae Wan; Lee, Jung-Hyun; Kang, Sung Gyun

    2015-01-01

    Among four basic mechanisms for biological hydrogen (H2) production, dark fermentation has been considered to show the highest hydrogen evolution rate (HER). H2 production from one-carbon (C1) compounds such as formate and carbon monoxide (CO) is promising because formate is an efficient H2 carrier, and the utilization of CO-containing syngas or industrial waste gas may render the industrial biohydrogen production process cost-effective. A variety of microbes with the formate hydrogen lyase (FHL) system have been identified from phylogenetically diverse groups of archaea and bacteria, and numerous efforts have been undertaken to improve the HER for formate through strain optimization and bioprocess development. CO-dependent H2 production has been investigated to enhance the H2 productivity of various carboxydotrophs via an increase in CO gas-liquid mass transfer rates and the construction of genetically modified strains. Hydrogenogenic CO-conversion has been applied to syngas and by-product gas of the steel-mill process, and this low-cost feedstock has shown to be promising in the production of biomass and H2. Here, we focus on recent advances in the isolation of novel phylogenetic groups utilizing formate or CO, the remarkable genetic engineering that enhances H2 productivity, and the practical implementation of H2 production from C1 substrates. Copyright © 2014 Elsevier Inc. All rights reserved.

  17. Linear Optimization Techniques for Product-Mix of Paints Production in Nigeria

    Directory of Open Access Journals (Sweden)

    Sulaimon Olanrewaju Adebiyi

    2014-02-01

    Full Text Available Many paint producers in Nigeria do not lend themselves to flexible production process which is important for them to manage the use of resources for effective optimal production. These goals can be achieved through the application of optimization models in their resources allocation and utilisation. This research focuses on linear optimization for achieving product- mix optimization in terms of the product identification and the right quantity in paint production in Nigeria for better profit and optimum firm performance. The computational experiments in this research contains data and information on the units item costs, unit contribution margin, maximum resources capacity, individual products absorption rate and other constraints that are particular to each of the five products produced in the company employed as case study. In data analysis, linear programming model was employed with the aid LINDO 11 software to analyse the data. The result has showed that only two out of the five products under consideration are profitable. It also revealed the rate to which the company needs to reduce cost incurred on the three other products before making them profitable for production.

  18. Modelling production system architectures in the early phases of product development

    DEFF Research Database (Denmark)

    Guðlaugsson, Tómas Vignir; Ravn, Poul Martin; Mortensen, Niels Henrik

    2016-01-01

    are needed and appropriate to enable determination of obtainable product quality. In order to meet this challenge, it is suggested that a visual modelling framework be adopted that clarifies which product and production features are known at a specific time of the project and which features will be worked...... on – leading to an improved basis for prioritizing activities in the project. Requirements for the contents of the framework are presented, and literature on production and system models is reviewed. The production system architecture modelling framework is founded on methods and approaches in literature......This article suggests a framework for modelling a production system architecture in the early phases of product development.The challenge in these phases is that the products to be produced are not completely defined and yet decisions need to be made early in the process on what investments...

  19. Toyota production system beyond large-scale production

    CERN Document Server

    Ohno, Taiichi

    1998-01-01

    In this classic text, Taiichi Ohno--inventor of the Toyota Production System and Lean manufacturing--shares the genius that sets him apart as one of the most disciplined and creative thinkers of our time. Combining his candid insights with a rigorous analysis of Toyota's attempts at Lean production, Ohno's book explains how Lean principles can improve any production endeavor. A historical and philosophical description of just-in-time and Lean manufacturing, this work is a must read for all students of human progress. On a more practical level, it continues to provide inspiration and instruction for those seeking to improve efficiency through the elimination of waste.

  20. Use of radioimmunoassay technique for the determination of post-partum ovaric activity in high and low milk production in dairy cows

    International Nuclear Information System (INIS)

    Villalba, P.; Paneluisa, S.; Arcos, E.

    1993-01-01

    The principal objective of this study was to determinate the post-partum ovarian activity in milking cows of high and low production in one farm of ecuadorian highland. For this experiment was necessary to use 48 animals between second and sith calving, the milk samples were collected according one pre-stablished protocol and the same was: one sample 5th or 6th days, twice a week until the cows were pregnacy and 180 days after parturitium if the cow is open. Additional data were compiled in each farm and both the results of the progesterone by RIA were used to determinate the diferents reproductive parameters in the post-partum of the cows. The most of reproductives parameters in the post-partum of the cows in the both group didn't have significance but the conception rate, services per conception, number of pregnacy cows and percentaje of non visibles heats had one high significance between the treatments

  1. Production design and location in the Danish television drama series Arvingerne

    DEFF Research Database (Denmark)

    Ion Wille, Jakob; Waade, Anne Marit

    2016-01-01

    Television fiction is most often referred to as the writer’s medium, whereas feature film is generally perceived as the vision and work of the director. In this article we turn our focus to the role and function of the production design and locations in developing and conceptualising a television...... drama series. We use the drama series Arvingerne (The Legacy, DR, 2014-2015) to illustrate how design ideas can be developed at an early stage, in pre-pre-production, as part of a collective, creative process that includes the scriptwriter, the production designer and the producer. Our empirical study...... of the series draws on an analysis of in-house design/concept documents [1], interviews with the production designer Mia Stensgaard [2], and promotional material made for the series [3]. The paper also draws on visual analysis of the finished production. Our overall argument is that the importance of location...

  2. Production Function Geometry with "Knightian" Total Product

    Science.gov (United States)

    Truett, Dale B.; Truett, Lila J.

    2007-01-01

    Authors of principles and price theory textbooks generally illustrate short-run production using a total product curve that displays first increasing and then diminishing marginal returns to employment of the variable input(s). Although it seems reasonable that a temporary range of increasing returns to variable inputs will likely occur as…

  3. Market problems of agricultural products in Albania

    Directory of Open Access Journals (Sweden)

    Merita Marku

    2017-03-01

    Full Text Available The production of fruits and vegetables in our country still faces challenges, including informality in sector of planting material, high costs of inputs purchased and fuel (especially affecting the green houses with heating, low productivity and high losses of post-harvest, especially in the case of fruit. Fresh fruit and vegetable marketing is different in many respects from the marketing of other agricultural and nonagricultural products. Hundreds of individual commodities comprise the total group. Each product has its own special requirements for growing and handling, with its own quality attributes, merchandising methods, and standards of consumer acceptance (How, R. B. 2012, 1. Food safety standards of fruits and vegetables their compliance with key standards and certification as a prerequisite and a challenge to be addressed in order to increase Albanian exports of agricultural products to European markets. Concerning vegetables and fruits, Albanian farmers face important marketing problems. Such problems are encountered at all stages of the production system-provision of inputs, both in terms of processing, promotion and other market incentives, which directly assist in the efficient realization of the sale of fruits and vegetables.

  4. Beyond Research Productivity: Matching Productivity Measures to Institutional Mission

    Directory of Open Access Journals (Sweden)

    Patricia Bartholomew

    2016-11-01

    Full Text Available Aim/Purpose: The aim of this paper is to develop a unified methodology inclusive of the three primary areas of faculty responsibility (teaching, research, and service to calculate departmental productivity that fills the gap in methodological bench-marking tools for overall faculty productivity. Background:\tA disproportionate number of departmental and faculty productivity indices in higher education rely solely on research. Productivity in other areas of faculty workload areas, like teaching and institutional and community service, are either measured separately or ignored all together – even when those activities are institutionally mandated. This does a disservice to those who work in those institutions and skews incentives. Methodology: This paper utilizes a unified methodology inclusive of the three primary areas of faculty responsibility (teaching, research, and service to calculate depart-mental productivity in five disparate departments (English, Biology, Mathematics, Sociology, and Computer Science common to two universities with differing missions (teaching and service. Findings: The results reveal the bias inherent in relying solely on research as a proxy for overall productivity in institutions that have differing missions. Recommendations for Practitioners: Utilizing better metrics informs higher education administrators, promotes better decision-making, and allows incentives to re-align with desired outcomes. Recommendation for Researchers: This paper recommends combing all aspects of faculty workload into a single benchmark index to better measure departmental productivity. Future Research: Further research into improving this simple index is warranted and would include how to account for quality and other facets of productivity.

  5. Economical Production of Pu-238

    Energy Technology Data Exchange (ETDEWEB)

    Steven D. Howe; Douglas Crawford; Jorge Navarro; Terry Ring

    2013-02-01

    All space exploration missions traveling beyond Jupiter must use radioisotopic power sources for electrical power. The best isotope to power these sources is plutonium-238. The US supply of Pu-238 is almost exhausted and will be gone within the next decade. The Department of Energy has initiated a production program with a $10M allocation from NASA but the cost is estimated at over $100 M to get to production levels. The Center for Space Nuclear Research has conceived of a potentially better process to produce Pu-238 earlier and for significantly less cost. The new process will also produce dramatically less waste. Potentially, the front end costs could be provided by private industry such that the government only had to pay for the product produced. Under a NASA Phase I NIAC grant, the CSNR has evaluated the feasibility of using a low power, commercially available nuclear reactor to produce at least 1.5 kg of Pu-238 per year. The impact on the neutronics of the reactor have been assessed, the amount of Neptunium target material estimated, and the production rates calculated. In addition, the size of the post-irradiation processing facility has been established. In addition, a new method for fabricating the Pu-238 product into the form used for power sources has been identified to reduce the cost of the final product. In short, the concept appears to be viable, can produce the amount of Pu-238 needed to support the NASA missions, can be available within a few years, and will cost significantly less than the current DOE program.

  6. Productivity and Performance Measurement

    DEFF Research Database (Denmark)

    Hald, Kim Sundtoft; Spring, Martin

    This study explores conceptually how performance measurement as discussed in the literature, enables or constrains the ability to manage and improve productivity. It uses an inter-disciplinary literature review to identify five areas of concern relating productivity accounting to the ability...... to improve productivity: “Productivity representation”; “productivity incentives”, “productivity intervention”; “productivity trade-off or synergy” and “productivity strategy and context”. The paper discusses these areas of concern and expands our knowledge of how productivity and performance measurement...

  7. A Production Model for Deteriorating Inventory Items with Production Disruptions

    OpenAIRE

    Yong He; Ju He

    2010-01-01

    Disruption management has recently become an active area of research. In this study, an extension is made to consider the fact that some products may deteriorate during storage. A production-inventory model for deteriorating items with production disruptions is developed. Then the optimal production and inventory plans are provided, so that the manufacturer can reduce the loss caused by disruptions. Finally, a numerical example is used to illustrate the model.

  8. New salty waffle products "Fish Krekis" with fish & plant semifinished products

    Directory of Open Access Journals (Sweden)

    Fedorova Dina

    2016-04-01

    Full Text Available The study examines the directions of expansion of the range of wafer snack products of high nutritional value by using fish & plant semifinished products. The study scientifically grounds the benefits of using the new fish & plant semifinished products in manufacturing waffle salty snack products. The data provided in the article prove that the use of the fish & plant semifinished products & herbal ingredients enable a range of the new wafer snack products «Fish krekis» with high content of proteins, organic calcium, fiber and vitamins, with improved consumer properties, as well as more efficient use of Ukrainian raw fish materials.

  9. Product competitiveness analysis for e-commerce platform of special agricultural products

    Science.gov (United States)

    Wan, Fucheng; Ma, Ning; Yang, Dongwei; Xiong, Zhangyuan

    2017-09-01

    On the basis of analyzing the influence factors of the product competitiveness of the e-commerce platform of the special agricultural products and the characteristics of the analytical methods for the competitiveness of the special agricultural products, the price, the sales volume, the postage included service, the store reputation, the popularity, etc. were selected in this paper as the dimensionality for analyzing the competitiveness of the agricultural products, and the principal component factor analysis was taken as the competitiveness analysis method. Specifically, the web crawler was adopted to capture the information of various special agricultural products in the e-commerce platform ---- chi.taobao.com. Then, the original data captured thereby were preprocessed and MYSQL database was adopted to establish the information library for the special agricultural products. Then, the principal component factor analysis method was adopted to establish the analysis model for the competitiveness of the special agricultural products, and SPSS was adopted in the principal component factor analysis process to obtain the competitiveness evaluation factor system (support degree factor, price factor, service factor and evaluation factor) of the special agricultural products. Then, the linear regression method was adopted to establish the competitiveness index equation of the special agricultural products for estimating the competitiveness of the special agricultural products.

  10. The role of fission products in whole core accidents

    Energy Technology Data Exchange (ETDEWEB)

    Baker, A R [FRSD, UKAEA, RNPDE, Risley, Warrington (United Kingdom); Teague, H J [SRD, UKAEA, Culcheth, Warrington (United Kingdom)

    1977-07-01

    The review of the role of fission products in whole-core accidents falls into two parts. Firstly, there is a discussion of the hypothetical accidents usually considered in the UK and how they are dealt with. Secondly, there is a discussion of individual topics where fission products are known to be important or might be so. There is a brief discussion of the UK work on the establishment of an equation of state for unirradiated fuel and how this might be extended to incorporate fission product effects. The main issue is the contribution of fission products to the effective vapour pressure and the experimental programme on the pulsed reactor VIPER investigates this. Fission products may influence the probability of occurrence and the severity of MFCIs. Finally, the fission product effects in the pre-disassembly, disassembly and recriticality stages of an accident are discussed. (author)

  11. Performance Assessment of Multi-Source Weighted-Ensemble Precipitation (MSWEP Product over India

    Directory of Open Access Journals (Sweden)

    Akhilesh S. Nair

    2017-01-01

    Full Text Available Error characterization is vital for the advancement of precipitation algorithms, the evaluation of numerical model outputs, and their integration in various hydro-meteorological applications. The Tropical Rainfall Measuring Mission (TRMM Multi-satellite Precipitation Analysis (TMPA has been a benchmark for successive Global Precipitation Measurement (GPM based products. This has given way to the evolution of many multi-satellite precipitation products. This study evaluates the performance of the newly released multi-satellite Multi-Source Weighted-Ensemble Precipitation (MSWEP product, whose temporal variability was determined based on several data products including TMPA 3B42 RT. The evaluation was conducted over India with respect to the IMD-gauge-based rainfall for pre-monsoon, monsoon, and post monsoon seasons at daily scale for a 35-year (1979–2013 period. The rainfall climatology is examined over India and over four geographical extents within India known to be subject to uniform rainfall. The performance evaluation of rainfall time series was carried out. In addition to this, the performance of the product over different rainfall classes was evaluated along with the contribution of each class to the total rainfall. Further, seasonal evaluation of the MSWEP products was based on the categorical and volumetric indices from the contingency table. Upon evaluation it was observed that the MSWEP products show large errors in detecting the higher quantiles of rainfall (>75th and > 95th quantiles. The MSWEP precipitation product available at a 0.25° × 0.25° spatial resolution and daily temporal resolution matched well with the daily IMD rainfall over India. Overall results suggest that a suitable region and season-dependent bias correction is essential before its integration in hydrological applications. While the MSWEP was observed to perform well for daily rainfall, it suffered from poor detection capabilities for higher quantiles, making

  12. Occurrence of transformation products in the environment

    Science.gov (United States)

    Kolpin, Dana W.; Battaglin, William A.; Conn, Kathleen E.; Furlong, Edward T.; Glassmeyer, Susan T.; Kalkhoff, Stephen J.; Meyer, Michael T.; Schnoebelen, Douglas J.; Boxall, Alistair B.A.

    2009-01-01

    Historically, most environmental occurrence research has focused on the parent compounds of organic contaminants. Research, however, has documented that the environmental transport of chemicals, such as pesticides and emerging contaminants, are substantially underestimated if transformation products are not considered. Although most examples described herein were drawn from research conducted by the U.S. Geological Survey, such results are generally reflective of those found in other parts of the world. Results from a study of 51 streams in the Midwestern United States found that transformation products were seven of the ten most frequently detected pesticide compounds in late spring runoff (after application of pre-emergent herbicides), and nine of the ten most frequently detected compounds in fall season runoff (during and after harvest). In fact, 70% of the total herbicide concentration in water from the Mississippi River Basin was from transformation products. Results from a study of 86 municipal wells in Iowa found the frequency of detection increased from 17%, when pesticide parent compounds were considered, to 53%, when both parents and transformation products were considered. Transformation products were 12 of the 15 most frequently detected compounds for this groundwater study. Although studies on transformation products of synthetic organic compounds other than pesticides are not as common, wastewater treatment plant discharges have repeatedly been shown to contribute such transformation products to streams. In addition, select detergent transformation products have been commonly found in solid waste in the 1000's mg/kg. These findings and many others document that transformation products must be considered to fully assess the potential environmental occurrence of chemical contaminants and their transport and fate in various compartments of the hydrologic system. ?? 2008 Springer-Verlag Berlin Heidelberg.

  13. Ethanol production

    Energy Technology Data Exchange (ETDEWEB)

    Kolleurp, F; Daugulis, A J

    1985-05-01

    Extractive fermentation is a technique that can be used to reduce the effect of end-product inhibition through the use of a water-immiscible phase which removes fermentation products in situ. This has the beneficial effect of not only removing inhibitory products as they are formed (thus keeping reaction rates high) but also has the potential for reducing product recovery costs. We have chosen to examine the ethanol fermentation as a model system for end product inhibition and extractive fermentation, and have developed a computer model predicting the productivity enhancement possible with this technique. The model predicts an ethanol productivity of 82.6 g/L-h if a glucose feed of 750 g/L is fermented with a solvent having a distribution coefficient of 0.5 at a dilution rate of 5.0 h . This is more than 10 times higher than for a conventional chemostat fermentation of a 250 g/L glucose feed. In light of this, a systematic approach to extractive fermentation has been undertaken involving the screening of more than 1,000 solvents for their extractive properties. UNIFAC and UNIQUAC estimates of distribution coefficients and selectivities were compiled and ranked in a database, together with other important physical properties, such as density, surface tension and viscosity. Preliminary shake-flask and chemostat biocompatibility studies on the most promising solvents have been undertaken. The previous predictive, data base and experimental results are discussed.

  14. Economic production quantity models for imperfect product and service with rework

    OpenAIRE

    Tai, Allen H.

    2012-01-01

    When imperfect quality products are produced in a production process, rework may be performed to make them become serviceable. In an inventory system, items may deteriorate. Selling deteriorated items to customers will create negative impact on corporate image. In this paper, two economic production quantity (EPQ) models are proposed for deteriorating items with rework process. A single production-rework plant system and a system consists of $n$ production plants and one rework plant are cons...

  15. Product Platform Modeling

    DEFF Research Database (Denmark)

    Pedersen, Rasmus

    for customisation of products. In many companies these changes in the business environment have created a controversy between the need for a wide variety of products offered to the marketplace and a desire to reduce variation within the company in order to increase efficiency. Many companies use the concept...... other. These groups can be varied and combined to form different product variants without increasing the internal variety in the company. Based on the Theory of Domains, the concept of encapsulation in the organ domain is introduced, and organs are formulated as platform elements. Included......This PhD thesis has the title Product Platform Modelling. The thesis is about product platforms and visual product platform modelling. Product platforms have gained an increasing attention in industry and academia in the past decade. The reasons are many, yet the increasing globalisation...

  16. Estimating product-to-product variations in metal forming using force measurements

    NARCIS (Netherlands)

    Havinga, Gosse Tjipke; Van Den Boogaard, Ton

    2017-01-01

    The limits of production accuracy of metal forming processes can be stretched by the development of control systems for compensation of product-to-product variations. Such systems require the use of measurements from each semi-finished product. These measurements must be used to estimate the final

  17. Coordiantion by using Product Specifications in Product Development

    DEFF Research Database (Denmark)

    Terkelsen, Søren Bendix

    1997-01-01

    This paper is based on a case study. It treats the coordination by generating product specifications in product development. This paper contains three very important aspects, which cause a need for coordination, and call attention to the coordination mechanisms. The three aspects are task...... uncertainty, task complexity, and dependencies between activities. If one want to select coordination mechanisms, which improve the performance in product development, it is very important to have a knowledge about these three aspects. In the following the aspects are identified in the literature...

  18. Development of Product Availability Monitoring System In Production Unit In Automotive Component Industry

    Science.gov (United States)

    Hartono, Rachmad; Raharno, Sri; Yuwana Martawirya, Yatna; Arthaya, Bagus

    2018-03-01

    This paper described a methodology to monitor the availability of products in a production unit in the automotive component industry. Automotive components made are automotive components made through sheet metal working. Raw material coming into production unit in the form of pieces of plates that have a certain size. Raw materials that come stored in the warehouse. Data of raw each material in the warehouse are recorded and stored in a data base system. The material will then undergo several production processes in the production unit. When the material is taken from the warehouse, material data are also recorded and stored in a data base. The data recorded are the amount of material, material type, and date when the material is out of the warehouse. The material coming out of the warehouse is labeled with information related to the production processes that the material must pass. Material out of the warehouse is a product will be made. The products have been completed, are stored in the warehouse products. When the product is entered into the product warehouse, product data is also recorded by scanning the barcode contained on the label. By recording the condition of the product at each stage of production, we can know the availability of the product in a production unit in the form of a raw material, the product being processed and the finished product.

  19. Productivity changes in OECD healthcare systems: bias-corrected Malmquist productivity approach.

    Science.gov (United States)

    Kim, Younhee; Oh, Dong-Hyun; Kang, Minah

    2016-10-01

    This study evaluates productivity changes in the healthcare systems of 30 Organization for Economic Co-operation and Development (OECD) countries over the 2002-2012 periods. The bootstrapped Malmquist approach is used to estimate bias-corrected indices of healthcare performance in productivity, efficiency and technology by modifying the original distance functions. Two inputs (health expenditure and school life expectancy) and two outputs (life expectancy at birth and infant mortality rate) are used to calculate productivity growth. There are no perceptible trends in productivity changes over the 2002-2012 periods, but positive productivity improvement has been noticed for most OECD countries. The result also informs considerable variations in annual productivity scores across the countries. Average annual productivity growth is evenly yielded by efficiency and technical changes, but both changes run somewhat differently across the years. The results of this study assert that policy reforms in OECD countries have improved productivity growth in healthcare systems over the past decade. Countries that lag behind in productivity growth should benchmark peer countries' practices to increase performance by prioritizing an achievable trajectory based on socioeconomic conditions. For example, relatively inefficient countries in this study indicate higher income inequality, corresponding to inequality and health outcomes studies. Although income inequality and globalization are not direct measures to estimate healthcare productivity in this study, these issues could be latent factors to explain cross-country healthcare productivity for future research. Copyright © 2016 John Wiley & Sons, Ltd. Copyright © 2016 John Wiley & Sons, Ltd.

  20. What Happens to Integrated Product Development Models with Product/Service-System Approaches?

    DEFF Research Database (Denmark)

    Tan, Adrian; McAloone, Timothy Charles; Andreasen, Mogens Myrup

    2006-01-01

    Integrated Product Development (IPD) has traditionally focused on the development activities relating to physical technological artefacts. With the advent of business approaches for manufacturing firms based on providing customers the utility of integrated products and services – a term dubbed...... ‘product/service-systems (PSS)’ – companies need to extend their activities to include new dimensions of development. Within the paradigm of mass production and consumption, traditional product-oriented business strategies regarded physical technological artefacts (products) as the mediators of customer...... value. Value was based on the exchange of products between a providing company and a receiving customer. The more products the company could sell, the more revenue it generated. At the point of sale the ownership and responsibility of the product was transferred from company to customer. A customer...

  1. Defining product intake fraction to quantify and compare exposure to consumer products

    DEFF Research Database (Denmark)

    Jolliet, Oliver; Ernstoff, Alexi; Csiszar, Susan A.

    2015-01-01

    There is a growing consciousness that exposure studies need to better cover near-field exposure associated with products use. To consistently and quantitatively compare human exposure to chemicals in consumer products, we introduce the concept of product intake fraction, as the fraction...... of a chemical within a product that is eventually taken in by the human population. This metric enables consistent comparison of exposures during consumer product use for different product-chemical combinations, exposure duration, exposure routes and pathways and for other life cycle stages. We present example...... modalities within life cycle assessment and risk assessment contexts. The product intake fraction helps to provide a clear interface between the life cycle inventory and impact assessment phases, to identify best suited sentinel products and to calculate overall exposure to chemicals in consumer products...

  2. Picture archiving and communication systems lead to sustained improvements in reporting times and productivity: results of a 5-year audit

    Energy Technology Data Exchange (ETDEWEB)

    Mackinnon, A.D.; Billington, R.A.; Adam, E.J.; Dundas, D.D. [Department of Radiology, St Georges Hospital NHS Trust, London (United Kingdom); Patel, U. [Department of Radiology, St Georges Hospital NHS Trust, London (United Kingdom)], E-mail: Uday.Patel@stgeorges.nhs.uk

    2008-07-15

    Aim: To evaluate the impact of picture archiving and communications systems (PACS) on reporting times and productivity in a large teaching hospital. Materials and methods: Reporting time, defined as the time taken from patient registration to report availability, and productivity, defined as the number of reports issued per whole time equivalent (WTE) radiologist per month, were studied for 2 years pre- and 3 years post-PACS installation. Mean reporting time was calculated for plain radiographs and specialist radiology techniques [computed tomography (CT), magnetic resonance imaging (MRI), ultrasound, and nuclear medicine]. Productivity, total department workload, and unreported film rates were also assessed. Pre- and post-PACS findings were compared. Results: Between 2002-2006 the number of radiological patient episodes increased by 30% from 11,531/month to 15,057/month. This was accompanied by a smaller increase in WTE reporting radiologists, from 32 to 37 (15%). Mean reporting times have improved substantially post-PACS, plain radiograph reporting time decreased by 26% (from 6.8 to 5 days; p = 0.002) and specialty modalities by 24% (4.1 to 3.1 days; p < 0.001). Radiologist productivity has increased by 18% (337 films to 407 films/WTE radiologist/month). Unreported films have decreased from 5 to 4% for plain radiographs and are steady for specialty modalities (< 1%). In most areas improvements have been sustained over a 3-year period. Conclusion: Since the introduction of PACS, reporting times have decreased by 25% and the productivity improved by 18%. Sustained improvements are felt to reflect the efficiencies and cultural change that accompanied the introduction of PACS and digital dictation.

  3. QUANTIFYING SUPPLIERS’ PRODUCT QUALITY: AN EXPLORATORY PRODUCT AUDIT METHOD

    Directory of Open Access Journals (Sweden)

    S. Avakh Darestani

    2012-01-01

    Full Text Available

    ENGLISH ABSTRACT:The quality of the raw material and supplied product from suppliers plays a critical role in the quality of the final product. It has become the norm that vehicle manufacturers require their suppliers to measure product quality and service with a product audit method. Measuring quality of product is emphasised by QS9000 VDA6.5 and ISO/TS16949. From a competitive standpoint, and also to see continuous improvement in business, companies need to monitor their suppliers’ performance. Quality and delivery are two very important indicators of supplier performance. This paper presents a statistical method for measuring the quality of supplied product. This method allocates different weights to variables and attributes characteristics. Moreover, following normal distribution, the tolerance zone is divided to three regions with different scores. Therefore, the quality of suppliers’ products can be monitored based on the Product Quality Audit Score (PQAS. However, this method may be employed for organisations to monitor their raw material, work-in-process parts, and final product. It can be an indicator to monitor supplier quality behaviour.

    AFRIKAANSE OPSOMMING: Die gehalte van grondstowwe en produkte/komponente wat deur leweransiers verskaf word, speel ‘n kritiese rol in die gehalte van die finale produk. Dit het die norm geword in die motorvervaardigingsbedryf dat daar van leweransiers verwag word om hulle produkkwaliteit en –diens te meet by wyse van ‘n produkouditmetode. Die meting van produkkwaliteit word benadruk deur QS9000 VDA6.5 en ISO/TS16949. Uit ‘n mededingingshoek en ook om kontinue verbetering te monitor, is dit noodsaaklik dat leweransiers se verrigting gemeet word. Gehalte en aflewering is twee van die belangrikste indikatore van leweransiersverrigting. In hierdie artikel word ‘n statistiese model voorgehou vir die meting van die kwaliteit van die gelewerde produk. Die metode ken verskillende

  4. Reassigning the Structures of Natural Products Using NMR Chemical Shifts Computed with Quantum Mechanics: A Laboratory Exercise

    Science.gov (United States)

    Palazzo, Teresa A.; Truong, Tiana T.; Wong, Shirley M. T.; Mack, Emma T.; Lodewyk, Michael W.; Harrison, Jason G.; Gamage, R. Alan; Siegel, Justin B.; Kurth, Mark J.; Tantillo, Dean J.

    2015-01-01

    An applied computational chemistry laboratory exercise is described in which students use modern quantum chemical calculations of chemical shifts to assign the structure of a recently isolated natural product. A pre/post assessment was used to measure student learning gains and verify that students demonstrated proficiency of key learning…

  5. COTTAGE CHEESE PRODUCTS FUNCTIONALITY

    Directory of Open Access Journals (Sweden)

    L. V. Golubeva

    2015-01-01

    Full Text Available Cottage cheese products holds a significant place among the dairy and milk-containing products. The range of products includes cheese: cheese, pastes, creams, cakes, etc. Such diversity can be attributed to their popularity among the population and benefit brought by the body from regular use. Curd protein is much better and easier to digest by the body than protein fish, meat or milk. Rich curd products lysine and methionine. Minerals contained in cheese products have a positive effect on bone formation and structure of tissues. The composition of curd products, in addition to cheese and dairy ingredients may include non-dairy ingredients origin. Today, for the production of cheese products use the most advanced technologies to further enrich its structure and significantly improve the nutritional value. Pine nut is widely used in the manufacture of many dairy products. But, in most cases, the production of dairy products as a filler used pine nut cake, which deprives the finished product valuable cedar oil. The authors proposed a technology for producing curd product with the addition of pine nuts and honey (pine nuts and fructose. Compatible with cream cheese filling insertion determined sensory organoleptic point scale. he optimum dosage of components: pine nuts – 5 %, honey – 10 % fructose – 7 %. Technological process of cottage cheese product is different from the traditional operations training components and their introduction into the finished cheese. Identify indicators of quality of the new product. Production of curd products thus expanding the range of dairy products functional orientation.

  6. The potential mechanism of Bursal-derived BPP-II on the antibody production and avian pre-B cell.

    Science.gov (United States)

    Feng, Xiuli; Cao, Ruibing; Zhou, Bin; Liu, Qingtao; Liu, Ke; Liu, Xiaodong; Zhang, Yuanpeng; Gu, Jinyan; Miao, Denian; Chen, Puyan

    2013-03-01

    The bursa of Fabricius is critical for the normal development of the B lymphocytes responsible for antibody production. However, the mechanism of the bursal-derived bioactive factor on B cell development is little reported. In this paper, chicks were immunized with BPP-II and AIV vaccine or AIV antigen, and antibody and IL-4 production were detected. The results showed that BPP-II played strongly inducing roles on the humoral immune responses. To investigate the gene expression at transcriptional level, avian pre-B lymphocyte DT40 cells were treated with BPP-II, and were analyzed with the gene microarray. The results proved that BPP-II treatment regulated 11 pathways, in which homologous recombination is a vital mechanism which is involved in antibody Ig gene conversion and diversification during B cell development. These results suggested Bursal-derived biological active factor BPP-II might be involved in the antibody production processes and B cell development, which is vital to the humoral central immune organ, the bursa of Fabricius. Copyright © 2012 Elsevier Ltd. All rights reserved.

  7. Production of polyhydroxyalcanoates (PHAs) using milk whey and dairy wastewater activated sludge production of bioplastics using dairy residues.

    Science.gov (United States)

    Bosco, Francesca; Chiampo, Fulvia

    2010-04-01

    The production of polyhydroxyalcanoates (PHAs), which are biodegradable plastics, was studied using milk whey and dairy wastewater activated sludge to define a suitable C/N ratio, the pre-treatments required to reduce the protein content, and the effect of pH correction. The results show good production of PHAs at a C/N=50 and without pH correction. The use of dairy wastewater activated sludge has the advantage of not requiring aseptic conditions. Copyright 2009 The Society for Biotechnology, Japan. Published by Elsevier B.V. All rights reserved.

  8. Tunnel production enhances quality in organic carrot seed production

    DEFF Research Database (Denmark)

    Deleuran, L C; Boelt, B

    2009-01-01

    production of open-pollinated carrot varieties increased the yield and germination percentages when compared with normal field conditions. Yield was in the range of 100-250 g and 2-17 g seeds m-2 respectively, and germination percentage was 84-95 and 43-55, respectively. However, hybrid carrot seed...... production showed lower yields than did their open-pollinated counterparts. Yields ranging from 60-123 g seeds m-2 can be obtained, but the production needs to be carefully planned and monitored. Different growing systems in tunnels have been studied in both open-pollinated and hybrid carrot (Daucus carota L......In Denmark, organic vegetable seed production is possible for some of the late-maturing species when the maturing is performed in lightweight tunnels which are also relevant for the isolation of small-scale production. The tunnel system offers several advantages, e.g., it is possible to control...

  9. Electronic medical records and efficiency and productivity during office visits.

    Science.gov (United States)

    Furukawa, Michael F

    2011-04-01

    To estimate the relationship between electronic medical record (EMR) use and efficiency of utilization and provider productivity during visits to US office-based physicians. Cross-sectional analysis of the 2006-2007 National Ambulatory Medical Care Survey. The sample included 62,710 patient visits to 2625 physicians. EMR systems included demographics, clinical notes, prescription orders, and laboratory and imaging results. Efficiency was measured as utilization of examinations, laboratory tests, radiology procedures, health education, nonmedication treatments, and medications. Productivity was measured as total services provided per 20-minute period. Survey-weighted regressions estimated association of EMR use with services provided, visit intensity/duration, and productivity. Marginal effects were estimated by averaging across all visits and by major reason for visit. EMR use was associated with higher probability of any examination (7.7%, 95% confidence interval [CI] = 2.4%, 13.1%); any laboratory test (5.7%, 95% CI = 2.6%, 8.8%); any health education (4.9%, 95% CI = 0.2%, 9.6%); and fewer laboratory tests (-7.1%, 95% CI = -14.2%, -0.1%). During pre/post surgery visits, EMR use was associated with 7.3% (95% CI= -12.9%, -1.8%) fewer radiology procedures. EMR use was not associated with utilization of nonmedication treatments and medications, or visit duration. During routine visits for a chronic problem, EMR use was associated with 11.2% (95% CI = 5.7%, 16.8%) more diagnostic/screening services provided per 20-minute period. EMR use had a mixed association with efficiency and productivity during office visits. EMRs may improve provider productivity, especially during visits for a new problem and routine chronic care.

  10. Value Added Productivity Indicators: A Statistical Comparison of the Pre-Test/Post-Test Model and Gain Model.

    Science.gov (United States)

    Weerasinghe, Dash; Orsak, Timothy; Mendro, Robert

    In an age of student accountability, public school systems must find procedures for identifying effective schools, classrooms, and teachers that help students continue to learn academically. As a result, researchers have been modeling schools and classrooms to calculate productivity indicators that will withstand not only statistical review but…

  11. Biohydrogen production from a novel alkalophilic isolate Clostridium sp. IODB-O3.

    Science.gov (United States)

    Patel, Anil Kumar; Debroy, Arundhati; Sharma, Sandeep; Saini, Reetu; Mathur, Anshu; Gupta, Ravi; Tuli, Deepak Kumar

    2015-01-01

    Hydrogen producing bacteria IODB-O3 was isolated from sludge and identified as Clostridium sp. by 16S rDNA gene analysis. In this study, biohydrogen production process was developed using low-cost agro-waste. Maximum H2 was produced at 37°C and pH 8.5. Maximum H2 yield was obtained 2.54±0.2mol-H2/mol-reducing sugar from wheat straw pre-hydrolysate (WSPH) and 2.61±0.1mol-H2/mol-reducing sugar from pre-treated wheat straw enzymatic-hydrolysate (WSEH). The cumulative H2 production (ml/L), 3680±105 and 3270±100, H2 production rate (ml/L/h), 153±5 and 136±5, and specific H2 production (ml/g/h), 511±5 and 681±10 with WSPH and WSEH were obtained, respectively. Biomass pre-treatment via steam-explosion generates ample amount of WSPH which remains unutilized for bioethanol production due to non-availability of efficient C5-fermenting microorganisms. This study shows that Clostridium sp. IODB-O3 is capable of utilizing WSPH efficiently for biohydrogen production. This would lead to reduced economic constrain on the overall cellulosic ethanol process and also establish a sustainable biohydrogen production process. Copyright © 2014 Elsevier Ltd. All rights reserved.

  12. Bacillus cereus in fresh ricotta: Comparison of growth and Haemolysin BL production after artificial contamination during production or post processing

    DEFF Research Database (Denmark)

    Tirloni, Erica; Ghelardi, Emilia; Celandroni, Francesco

    2017-01-01

    . At 10 °C, GPe2 strain showed a slow growth, with similar rates between whey- or product-inoculated ricotta samples. The production of HBL toxin was significant only in samples kept at 15 °C, starting from the 4th day of storage. In order to ensure the consumers’ protection, these results suggest...

  13. Amateur Creation and Entrepreneurialism: A Critical Study of Artistic Production in Post-Fordist Structures

    OpenAIRE

    Yiannis Mylonas

    2012-01-01

    Based on an interview with a hip-hop artist from Eastern Poland, this article critically assesses amateur art pro-duction proliferating throughout the globe today through individuals’ creative usages of new ICTs and new media affordances. The post-Fordist material and ideological context of contemporary social life is the main focus point of the article’s critique. Scarcity, dispossession, and entrepreneurship are the main analytical concepts used to develop a critical analysis and explanatio...

  14. Evaluating the Impact of a New Product on the Sales of other Products

    Directory of Open Access Journals (Sweden)

    Julian Andreev Vasilev

    2014-12-01

    Full Text Available The purpose of this article is to evaluate the impact of a new product on the sales of other products. Launching a new product may lead to increase or decrease of sales in the products of the same group. Customers may continue buying standard products or they may be oriented to new products. New products may cause internal competition. Statistical methods are applied. Time series analysis is used. Transactional database of a confectionary factory is the main source of data. The time series analysis is carried in two datasets – quantities of sales of three products on a daily basis and on a monthly basis. The main methods used are time series analysis and regression analysis. The three time series (corresponding to the three products are separated into two parts – before and after launching the new product. It is proved that the new product does not affect the sales of the two other products. The new product is well accepted and its sales increase together with the sales of the two other products.

  15. Comparison of Employer Productivity Metrics to Lost Productivity Estimated by Commonly Used Questionnaires.

    Science.gov (United States)

    Gardner, Bethany T; Dale, Ann Marie; Buckner-Petty, Skye; Van Dillen, Linda; Amick, Benjamin C; Evanoff, Bradley

    2016-02-01

    The aim of the study was to assess construct and discriminant validity of four health-related work productivity loss questionnaires in relation to employer productivity metrics, and to describe variation in economic estimates of productivity loss provided by the questionnaires in healthy workers. Fifty-eight billing office workers completed surveys including health information and four productivity loss questionnaires. Employer productivity metrics and work hours were also obtained. Productivity loss questionnaires were weakly to moderately correlated with employer productivity metrics. Workers with more health complaints reported greater health-related productivity loss than healthier workers, but showed no loss on employer productivity metrics. Economic estimates of productivity loss showed wide variation among questionnaires, yet no loss of actual productivity. Additional studies are needed comparing questionnaires with objective measures in larger samples and other industries, to improve measurement methods for health-related productivity loss.

  16. Comparison of employer productivity metrics to lost productivity estimated by commonly used questionnaires

    Science.gov (United States)

    Gardner, Bethany T.; Dale, Ann Marie; Buckner-Petty, Skye; Van Dillen, Linda; Amick, Benjamin C.; Evanoff, Bradley

    2016-01-01

    Objective To assess construct and discriminant validity of four health-related work productivity loss questionnaires in relation to employer productivity metrics, and to describe variation in economic estimates of productivity loss provided by the questionnaires in healthy workers. Methods 58 billing office workers completed surveys including health information and four productivity loss questionnaires. Employer productivity metrics and work hours were also obtained. Results Productivity loss questionnaires were weakly to moderately correlated with employer productivity metrics. Workers with more health complaints reported greater health-related productivity loss than healthier workers, but showed no loss on employer productivity metrics. Economic estimates of productivity loss showed wide variation among questionnaires, yet no loss of actual productivity. Conclusions Additional studies are needed comparing questionnaires with objective measures in larger samples and other industries, to improve measurement methods for health-related productivity loss. PMID:26849261

  17. Natural or Induced: Identifying Natural and Induced Swarms from Pre-production and Co-production Microseismic Catalogs at the Coso Geothermal Field

    Science.gov (United States)

    Schoenball, Martin; Kaven, Joern; Glen, Jonathan M. G.; Davatzes, Nicholas C.

    2015-01-01

    Increased levels of seismicity coinciding with injection of reservoir fluids have prompted interest in methods to distinguish induced from natural seismicity. Discrimination between induced and natural seismicity is especially difficult in areas that have high levels of natural seismicity, such as the geothermal fields at the Salton Sea and Coso, both in California. Both areas show swarm-like sequences that could be related to natural, deep fluid migration as part of the natural hydrothermal system. Therefore, swarms often have spatio-temporal patterns that resemble fluid-induced seismicity, and might possibly share other characteristics. The Coso Geothermal Field and its surroundings is one of the most seismically active areas in California with a large proportion of its activity occurring as seismic swarms. Here we analyze clustered seismicity in and surrounding the currently produced reservoir comparatively for pre-production and co-production periods. We perform a cluster analysis, based on the inter-event distance in a space-time-energy domain to identify notable earthquake sequences. For each event j, the closest previous event i is identified and their relationship categorized. If this nearest neighbor’s distance is below a threshold based on the local minimum of the bimodal distribution of nearest neighbor distances, then the event j is included in the cluster as a child to this parent event i. If it is above the threshold, event j begins a new cluster. This process identifies subsets of events whose nearest neighbor distances and relative timing qualify as a cluster as well as a characterizing the parent-child relationships among events in the cluster. We apply this method to three different catalogs: (1) a two-year microseismic survey of the Coso geothermal area that was acquired before exploration drilling in the area began; (2) the HYS_catalog_2013 that contains 52,000 double-difference relocated events and covers the years 1981 to 2013; and (3) a

  18. Modeling oil production based on symbolic regression

    International Nuclear Information System (INIS)

    Yang, Guangfei; Li, Xianneng; Wang, Jianliang; Lian, Lian; Ma, Tieju

    2015-01-01

    Numerous models have been proposed to forecast the future trends of oil production and almost all of them are based on some predefined assumptions with various uncertainties. In this study, we propose a novel data-driven approach that uses symbolic regression to model oil production. We validate our approach on both synthetic and real data, and the results prove that symbolic regression could effectively identify the true models beneath the oil production data and also make reliable predictions. Symbolic regression indicates that world oil production will peak in 2021, which broadly agrees with other techniques used by researchers. Our results also show that the rate of decline after the peak is almost half the rate of increase before the peak, and it takes nearly 12 years to drop 4% from the peak. These predictions are more optimistic than those in several other reports, and the smoother decline will provide the world, especially the developing countries, with more time to orchestrate mitigation plans. -- Highlights: •A data-driven approach has been shown to be effective at modeling the oil production. •The Hubbert model could be discovered automatically from data. •The peak of world oil production is predicted to appear in 2021. •The decline rate after peak is half of the increase rate before peak. •Oil production projected to decline 4% post-peak

  19. Aviation fuel and future oil production scenarios

    International Nuclear Information System (INIS)

    Nygren, Emma; Aleklett, Kjell; Hoeoek, Mikael

    2009-01-01

    Most aviation fuels are jet fuels originating from crude oil. Crude oil must be refined to be useful and jet fuel is only one of many products that can be derived from crude oil. Jet fuel is extracted from the middle distillates fraction and competes, for example, with the production of diesel. Crude oil is a limited natural resource subject to depletion and several reports indicate that the world's crude oil production is close to the maximum level and that it will start to decrease after reaching this maximum. A post-Kyoto political agenda to reduce oil consumption will have the same effect on aviation fuel production as a natural decline in the crude oil production. On the other hand, it is predicted by the aviation industry that aviation traffic will keep on increasing. The industry has put ambitious goals on increases in fuel efficiency for the aviation fleet. Traffic is predicted to grow by 5% per year to 2026, fuel demand by about 3% per year. At the same time, aviation fuel production is predicted to decrease by several percent each year after the crude oil production peak is reached resulting in a substantial shortage of jet fuel by 2026. The aviation industry will have a hard time replacing this with fuel from other sources, even if air traffic remains at current levels.

  20. Optimized Production of Vanillin from Green Vanilla Pods by Enzyme-Assisted Extraction Combined with Pre-Freezing and Thawing

    Directory of Open Access Journals (Sweden)

    Yanjun Zhang

    2014-02-01

    Full Text Available Production of vanillin from natural green vanilla pods was carried out by enzyme-assisted extraction combined with pre-freezing and thawing. In the first step the green vanilla pods were pre-frozen and then thawed to destroy cellular compartmentation. In the second step pectinase from Aspergillus niger was used to hydrolyze the pectin between the glucovanillin substrate and β-glucosidase. Four main variables, including enzyme amount, reaction temperature, time and pH, which were of significance for the vanillin content were studied and a central composite design (CCD based on the results of a single-factor tests was used. Response surface methodology based on CCD was employed to optimize the combination of enzyme amount, reaction temperature, time, and pH for maximum vanillin production. This resulted in the optimal condition in regards of the enzyme amount, reaction temperature, time, and pH at 84.2 mg, 49.5 °C, 7.1 h, and 4.2, respectively. Under the optimal condition, the experimental yield of vanillin was 4.63% ± 0.11% (dwb, which was in good agreement with the value predicted by the model. Compared to the traditional curing process (1.98% and viscozyme extract (2.36%, the optimized method for the vanillin production significantly increased the yield by 133.85% and 96%, respectively.

  1. Sustainable Industrial Product Systems. Integration of Life Cycle Assessment in Product development and Optimization of Product Systems

    Energy Technology Data Exchange (ETDEWEB)

    Hanssen, Ole Joergen

    1997-12-31

    This thesis contributes to the development and testing of environmental life cycle assessment (LCA) in product development and management in industry. It is based on systems theory and systems engineering. It develops a method for sustainable product development that has been successfully tested in the Nordic project called NEP. The LCA method is also a basis for an optimization model, where life cycle economy and environmental impacts from product systems are optimized with a non-linear model. A more complete mathematical model for LCA, based on the functional requirements on a product system, is also developed. The statistical properties of emission factors are studied using a data set from the Swedish Kraft Mill industry. It is shown that emission factors may be assumed constants in the LCA model, but with rather large variations within a population of Kraft mills. It is shown that there are a few environmental impacts which are important for most types of products under Scandinavian conditions, especially global warming potential, acidification, human toxicity and fossil energy depletion. There are significant differences between the contribution to these impacts from different life cycle stages, where raw material processing and use of products are generally more important than the other stages. Test cases indicate that there are no large conflicts between improvements in environmental impacts and customer requirements. Environmental improvements seem to increase purchase cost of products in some cases, but the life cycle cost of the products seem in most cases to be reduced. It is concluded that there are opportunities for 30-50% improvements in product system, based on relatively simple modifications of the systems. 246 refs., 63 figs., 19 tabs.

  2. Genome engineering for microbial natural product discovery.

    Science.gov (United States)

    Choi, Si-Sun; Katsuyama, Yohei; Bai, Linquan; Deng, Zixin; Ohnishi, Yasuo; Kim, Eung-Soo

    2018-03-03

    The discovery and development of microbial natural products (MNPs) have played pivotal roles in the fields of human medicine and its related biotechnology sectors over the past several decades. The post-genomic era has witnessed the development of microbial genome mining approaches to isolate previously unsuspected MNP biosynthetic gene clusters (BGCs) hidden in the genome, followed by various BGC awakening techniques to visualize compound production. Additional microbial genome engineering techniques have allowed higher MNP production titers, which could complement a traditional culture-based MNP chasing approach. Here, we describe recent developments in the MNP research paradigm, including microbial genome mining, NP BGC activation, and NP overproducing cell factory design. Copyright © 2018 Elsevier Ltd. All rights reserved.

  3. Real Time Part Input Control of a Pull Production System by Finding IF-THEN Rules

    Science.gov (United States)

    Ramli, Rizauddin; Yamamoto, Hidehiko; Abu Qudeiri, Jaber

    This paper considers the part input problem of a production system where two Flexible Transfer Lines (FTLs) consisting of an up-stream production line and a down-stream production line while operating under Just In Time (JIT) production management. The up-stream production line processes the raw material after receiving them from suppliers, and after processing them, delivers the processed product to a down-stream production line via a conveyer. In this paper, we have proposed a novel idea for a part input real time control system, known as Algorithm for Real Time Control of Part Input Systems (ARTCOPS). The algorithm is useful when FTLs are in operation under a production order that is different from the pre-decided production schedule. Simulations of virtual production systems have been carried out to verify that ARTCOPS is useful in real time control, although the production orders are different from the pre-decided production scheduling.

  4. Advances in the industrial production of halal and kosher red meat.

    Science.gov (United States)

    Farouk, Mustafa M

    2013-12-01

    The worldwide volume and value of trade in halal and kosher meat and co-products are huge. Muslim countries alone consumed meat estimated to be worth USD 57.2 billion in 2008. The halal and kosher principles that govern the production of red meat have many similarities, as well as some fundamental differences. Perhaps the most significant difference is that at the time of slaughter, the animal needs only to be alive to meet the minimum halal requirement, but must be both alive and conscious for kosher. It is for this reason that reversible pre-slaughter stunning is acceptable only for halal meat, although a compromise form of post-slaughter stunning is now considered kosher in some countries. Extensive research on animal physiology and welfare has characterised and optimised the methods for stunning livestock, and enabled advancement in associated technologies. This forms the basis for harmonising the religious and secular requirements for the protection of animal welfare at slaughter. These technologies and the associated processing practices for the industrial production of halal and kosher meat are reviewed in this paper. Copyright © 2013 Elsevier Ltd. All rights reserved.

  5. Product Category Layout and Organization: Retail Placement of Food Products

    NARCIS (Netherlands)

    Herpen, van E.

    2016-01-01

    This article discusses the placement of food products in retail stores, in particular how the placement of food products can influence how consumers perceive the store in general and these products in particular. It reviews the overall layout of the store, assortment organization, and shelf

  6. Biofuels versus food production: Does biofuels production increase food prices?

    International Nuclear Information System (INIS)

    Ajanovic, Amela

    2011-01-01

    Rapidly growing fossil energy consumption in the transport sector in the last two centuries caused problems such as increasing greenhouse gas emissions, growing energy dependency and supply insecurity. One approach to solve these problems could be to increase the use of biofuels. Preferred feedstocks for current 1st generation biofuels production are corn, wheat, sugarcane, soybean, rapeseed and sunflowers. The major problem is that these feedstocks are also used for food and feed production. The core objective of this paper is to investigate whether the recent increase of biofuels production had a significant impact on the development of agricultural commodity (feedstock) prices. The most important impact factors like biofuels production, land use, yields, feedstock and crude oil prices are analysed. The major conclusions of this analysis are: In recent years the share of bioenergy-based fuels has increased moderately, but continuously, and so did feedstock production, as well as yields. So far, no significant impact of biofuels production on feedstock prices can be observed. Hence, a co-existence of biofuel and food production seems possible especially for 2nd generation biofuels. However, sustainability criteria should be seriously considered. But even if all crops, forests and grasslands currently not used were used for biofuels production it would be impossible to substitute all fossil fuels used today in transport.

  7. Global product development

    DEFF Research Database (Denmark)

    Hansen, Zaza Nadja Lee; Ahmed-Kristensen, Saeema

    2011-01-01

    Globalisation has enabled companies to globalise their product development process. Today, everything from manufacturing to R&D can be globally distributed. This has led to a more complex and disintegrated product development process. This paper investigates the impacts companies have experienced...... operational solutions to counteract the negative impacts with varying degrees of success. This paper presents a unique look into global product development through an investigation of its impact on the organisation, the product development process, and the product. Furthermore, it shows the solutions...... as a result of this, and how they have been addressed. Data was collected through case studies of five Danish multinational corporations. The findings showed that the companies experienced several challenges when they globalised their product development process. They consequently implemented various...

  8. Product Platform Performance

    DEFF Research Database (Denmark)

    Munk, Lone

    The aim of this research is to improve understanding of platform-based product development by studying platform performance in relation to internal effects in companies. Platform-based product development makes it possible to deliver product variety and at the same time reduce the needed resources...... engaging in platform-based product development. Similarly platform assessment criteria lack empirical verification regarding relevance and sufficiency. The thesis focuses on • the process of identifying and estimating internal effects, • verification of performance of product platforms, (i...... experienced representatives from the different life systems phase systems of the platform products. The effects are estimated and modeled within different scenarios, taking into account financial and real option aspects. The model illustrates and supports estimation and quantification of internal platform...

  9. Formulation of a Production Strategy for a Software Product Line

    Science.gov (United States)

    2009-08-01

    Strategy 9 5.1 Identifying the Critical Factors 9 5.1.1 Market Analysis 10 5.1.2 Building a Business Case 10 5.1.3 Scoping 10 5.1.4 Technology...ability to deliver new products quickly (i.e., its time to market ). The production strategy for a software product line is the high-level description of... strategy . The critical factors mentioned above refer to both market conditions that affect an organ- ization and how an organization’s products can

  10. Product prioritization in a two-stage food production system with intermediate storage

    DEFF Research Database (Denmark)

    Akkerman, Renzo; van Donk, Dirk Pieter

    2007-01-01

    In the food-processing industry, usually a limited number of storage tanks for intermediate storage is available, which are used for different products. The market sometimes requires extremely short lead times for some products, leading to prioritization of these products, partly through...... the performance improvements for the prioritized product, as well as the negative effects for the other products. We also show how the effect decreases with more storage tanks, and increases with more products....... the dedication of a storage tank. This type of situation has hardly been investigated, although planners struggle with it in practice. This paper aims at investigating the fundamental effect of prioritization and dedicated storage in a two-stage production system, for various product mixes. We show...

  11. Heavy Flavour Production

    CERN Document Server

    Nason, Paolo; Ridolfi, Giovanni

    1995-01-01

    We review the status of heavy flavour production in QCD. Comparison of experimental and theoretical results for top and bottom production are given. Selected topics in charm production are also discussed.

  12. Effect of daily milk production on the economic impact of mastitits in cattle herds

    Directory of Open Access Journals (Sweden)

    Fabiana Alves Demeu

    2016-03-01

    Full Text Available The objectives of this study were to analyze and quantify the effect of daily productivity per animal on the economic impact of mastitis in dairy cattle herds. A simulation study was conducted using the CU$TO MASTITE computational program. Dairy herds with an average production of 10, 20 and 30 liters of milk/day were considered. As preventive measures, expenses with mastitis incidence monitoring (culture and antibiogram, somatic cell count in the tank and somatic cells count per animal, pre and post dipping, vaccination, and treatment of dry cows were computed. Treatments of clinical cases, which corresponded to 7% of all lactating cows, were considered as curative measures. The impact of mastitis was estimated as total losses (reduction in production and milk disposal during treatment and antibiotic withdrawal period plus expenses with prevention and treatment of clinical cases. An increase in daily productivity per animal reduced the economic impact of mastitis. Higher productivity was associated with lower economic impact values, per liter of commercialized milk, due to optimization of the products and materials used per animal, reducing operating expenses. The expenses with preventive treatment corresponded to a maximum of 13.5% of economic impact. This percentage was lower than the economic impact of expenses with curative treatment. These results demonstrate the advantages of investing in preventive treatment, which will contribute to reduce the economic impact of mastitis.

  13. Making online products more tangible : the effect of product presentation formats on product evaluations

    NARCIS (Netherlands)

    Verhagen, Tibert; Vonkeman, Charlotte; van Dolen, Willemijn

    2016-01-01

    Although several studies have looked at the effects of online product presentations on consumer decision making, no study thus far has considered a potential key factor in online product evaluations: tangibility. The present study aims at filling this gap by developing and testing a model that

  14. Manipulation of microtubers for direct field utilization in seed production

    NARCIS (Netherlands)

    Pruski, K.; Astatkie, T.; Duplessis, P.; Stewart, L.; Nowak, J.; Struik, P.C.

    2003-01-01

    A two-year field study was conducted to determine the effects of jasmonic acid (JA), light (during in vitro explant production and in vitro tuberization phases), and dormancy-breaking treatment on performance of microtubers in the production of seed tubers (pre-elite) in five potato cultivars.

  15. Production and distribution of livestock products in Aomori prefecture: Part 1

    International Nuclear Information System (INIS)

    Iyogi, Takashi; Hisamatsu, Shun'ichi; Inaba, Jiro

    2000-01-01

    We have collected natural and sociological environmental data related to the estimation of radiation dose by radionuclides which will be released from nuclear fuel cycle facilities. Published data concerning production and distribution of livestock products in Aomori Prefecture were collected and compiled. We tried to estimate market dilution coefficient, which is the ratio of local products to total consumption by people in a target area, for the livestock products from the compiled data under some assumptions. Production weight per unit field area (production density) and consumption rates of grass and feed by the domestic animals were also estimated by using the collected data. Estimated means of the market dilution coefficients for livestock products and production density of grass were lower than those used in the environmental assessment for a reprocessing plant now under construction in Rokkasho Village. Consumption rates of grass and feed by milk cows and beef cattle were higher than those used in the assessment. Since we assumed that milk cows and beef cattle of Aomori Prefecture consume only grass and feed produced in Aomori Prefecture, the rates may be overestimated. Further study is required to clarify this point. We collected 52 reports in the literature related to transfer reduction of radionuclides to livestock products and decontamination of the radionuclides. (author)

  16. Fuzzy production planning models for an unreliable production system with fuzzy production rate and stochastic/fuzzy demand rate

    Directory of Open Access Journals (Sweden)

    K. A. Halim

    2011-01-01

    Full Text Available In this article, we consider a single-unit unreliable production system which produces a single item. During a production run, the production process may shift from the in-control state to the out-of-control state at any random time when it produces some defective items. The defective item production rate is assumed to be imprecise and is characterized by a trapezoidal fuzzy number. The production rate is proportional to the demand rate where the proportionality constant is taken to be a fuzzy number. Two production planning models are developed on the basis of fuzzy and stochastic demand patterns. The expected cost per unit time in the fuzzy sense is derived in each model and defuzzified by using the graded mean integration representation method. Numerical examples are provided to illustrate the optimal results of the proposed fuzzy models.

  17. Generalized product

    OpenAIRE

    Greco, Salvatore; Mesiar, Radko; Rindone, Fabio

    2014-01-01

    Aggregation functions on [0,1] with annihilator 0 can be seen as a generalized product on [0,1]. We study the generalized product on the bipolar scale [–1,1], stressing the axiomatic point of view. Based on newly introduced bipolar properties, such as the bipolar increasingness, bipolar unit element, bipolar idempotent element, several kinds of generalized bipolar product are introduced and studied. A special stress is put on bipolar semicopulas, bipolar quasi-copulas and bipolar copulas.

  18. Workforce productivity.

    Science.gov (United States)

    Williams, Ruth

    2012-10-26

    Managers who are responsible for delivering the workforce productivity element of the Quality, Innovation, Productivity and Prevention (QIPP) programme can network and share best practice through a dedicated NHS Employers webpage.

  19. Spontaneously Reported Adverse Reactions for Herbal Medicinal Products and Natural Remedies in Sweden 2007-15: Report from the Medical Products Agency.

    Science.gov (United States)

    Svedlund, Erika; Larsson, Maria; Hägerkvist, Robert

    2017-06-01

    In relation to the extensive use of herbal medicinal products in self-care, the safety information is limited and there is a need for improvement. This study describes spontaneously reported adverse reactions related to herbal medicinal products and natural remedies in Sweden. To evaluate the characteristics and frequency of adverse events recorded by the Swedish Medical Products Agency, where herbal medicinal products and natural remedies were suspected as causative agents. Adverse drug reactions reported to the Swedish Medical Product Agency during 2007-15 related to approved herbal medicinal products or natural remedies were included and analysed in the retrospective study. Reports had been assessed for causality when they were lodged and only reports that had been assessed as at least possible were included in the study. In total, 116 reports (concerning 259 adverse reactions) related to herbal medicinal products or natural remedies were found in the Swedish national pharmacovigilance database. The active ingredients most frequently suspected during the study period were black cohosh rhizome (15 reports), purple coneflower herb (14 reports) and a combination of extracts of pollen (13 reports). Adverse reactions related to skin and subcutaneous tissue were the most commonly reported reactions. No previously unknown safety problems have been discovered in the present study. This finding could be explained by a thorough pre-approval assessment of medicinal products and the fact that most herbal preparations in medicinal products have been in clinical use for many years (for traditional herbal medicinal products, the requirements are ≥30 years), i.e. adverse reactions are acknowledged and assessed before approval.

  20. Productivity and production efficiency among small scale irrigated ...

    African Journals Online (AJOL)

    The study examined productivity and production efficiency among small scale irrigated sugarcane farmers in Niger State, Nigeria using a stochastic translog frontier function. Data for the study were obtained using structured questionnaires administered to 100 randomly selected sugarcane farmers from Paiko and Gurara ...

  1. Leading co-production

    DEFF Research Database (Denmark)

    Tortzen, Anne

    leadership styles executed by public managers affect the quality and public value of co-production processes? The paper argues that publicly initiated co-production initiatives are influenced by conflicting governance logics placing public managers in an institutional cross pressure (Lowndes & Roberts, 2013...... of building networks and relations, developing trust and focusing on empowerment and on the participants' resources to develop innovative solutions Drawing on three qualitative case studies of ‘most likely' co-production cases in Danish municipalities, the study identifies three different leadership styles...... and increase public value (Bovaird & Löffler, 2012; Osborne, 2010). The paper argues that a deeper understanding of the dynamics of co-production can be gained from analyzing the leadership dimension of co-production processes, which has hitherto not been given much attention by co-production researchers...

  2. Bioactive Compounds of Blueberries: Post-Harvest Factors Influencing the Nutritional Value of Products

    Directory of Open Access Journals (Sweden)

    Anna Michalska

    2015-08-01

    Full Text Available Blueberries, besides having commonly-recognized taste properties, are also a valuable source of health-promoting bioactive compounds. For several decades, blueberries have gained in popularity all over the world, and recent years have seen not only an increase in fresh consumption, but also in the importance of blueberries for the processing industry. Blueberry processing mostly consists of freezing and juicing. Recently, more attention has been drawn to dewatering and drying, which are promising areas for developing novel blueberry products. Processing affects each biologically-active compound in a different way, and it is still unknown what changes those compounds undergo at the molecular level after the application of different processing technologies. This work presents the most recent state of knowledge about the pre-treatment and processing methods applied to blueberries and their influence on the content of biologically-active compounds. The presentation of methods is preceded by a brief overview of the characteristics of the blueberry species, a description of the chemical composition of the fruit and a short note about the main growing areas, production volumes and the management of fruit crops.

  3. Bioactive Compounds of Blueberries: Post-Harvest Factors Influencing the Nutritional Value of Products

    Science.gov (United States)

    Michalska, Anna; Łysiak, Grzegorz

    2015-01-01

    Blueberries, besides having commonly-recognized taste properties, are also a valuable source of health-promoting bioactive compounds. For several decades, blueberries have gained in popularity all over the world, and recent years have seen not only an increase in fresh consumption, but also in the importance of blueberries for the processing industry. Blueberry processing mostly consists of freezing and juicing. Recently, more attention has been drawn to dewatering and drying, which are promising areas for developing novel blueberry products. Processing affects each biologically-active compound in a different way, and it is still unknown what changes those compounds undergo at the molecular level after the application of different processing technologies. This work presents the most recent state of knowledge about the pre-treatment and processing methods applied to blueberries and their influence on the content of biologically-active compounds. The presentation of methods is preceded by a brief overview of the characteristics of the blueberry species, a description of the chemical composition of the fruit and a short note about the main growing areas, production volumes and the management of fruit crops. PMID:26266408

  4. The economic production lot size model with several production rates

    DEFF Research Database (Denmark)

    Larsen, Christian

    should be chosen in the interval between the demand rate and the production rate, which minimize unit production costs, and should be used in an increasing order. Then, given the production rates, we derive closed form solutions for the optimal runtimes as well as the minimum average cost. Finally we...

  5. PREFER: a European service providing forest fire management support products

    Science.gov (United States)

    Eftychidis, George; Laneve, Giovanni; Ferrucci, Fabrizio; Sebastian Lopez, Ana; Lourenco, Louciano; Clandillon, Stephen; Tampellini, Lucia; Hirn, Barbara; Diagourtas, Dimitris; Leventakis, George

    2015-06-01

    PREFER is a Copernicus project of the EC-FP7 program which aims developing spatial information products that may support fire prevention and burned areas restoration decisions and establish a relevant web-based regional service for making these products available to fire management stakeholders. The service focuses to the Mediterranean region, where fire risk is high and damages from wildfires are quite important, and develop its products for pilot areas located in Spain, Portugal, Italy, France and Greece. PREFER aims to allow fire managers to have access to online resources, which shall facilitate fire prevention measures, fire hazard and risk assessment, estimation of fire impact and damages caused by wildfire as well as support monitoring of post-fire regeneration and vegetation recovery. It makes use of a variety of products delivered by space borne sensors and develop seasonal and daily products using multi-payload, multi-scale and multi-temporal analysis of EO data. The PREFER Service portfolio consists of two main suite of products. The first refers to mapping products for supporting decisions concerning the Preparedness/Prevention Phase (ISP Service). The service delivers Fuel, Hazard and Fire risk maps for this purpose. Furthermore the PREFER portfolio includes Post-fire vegetation recovery, burn scar maps, damage severity and 3D fire damage assessment products in order to support relative assessments required in context of the Recovery/Reconstruction Phase (ISR Service) of fire management.

  6. A test trial irradiation of natural rubber latex on large scale for the production of examination gloves in a production scale

    International Nuclear Information System (INIS)

    Devendra, R.; Kulatunge, S.; Chandralal, H.N.K.K.; Kalyani, N.M.V.; Seneviratne, J.; Wellage, S.

    1996-01-01

    Radiation Vulcanization of natural rubber latex has been developed extensively through various research and development programme. During these investigations many data was collected and from these data it was proved that radiation vulcanized natural rubber latex (RVNRL) can be used as a new material for industry (RVNRL symposium 1989; Makuuchi IAEA report). This material has been extensively tested in making of dipped goods and extruded products. However these investigations were confined only to laboratory experiments and these experiments mainly reflected material properties of RVNRL and only a little was observed about its behavior in actual production scale operation. The present exercise was carried out mainly to study the behavior of the material in production scale by irradiating latex on a large scale and producing gloves in a production scale plant. It was found that RVNRL can be used in conventional glove plants without making major alteration to the plant. Quality of the gloves that were produced using RVNRL is acceptable. It was also found that the small deviation of vulcanization dose will affect the crosslinking density of films. This will drastically reduce the tensile strength of the film. Crosslinking density or pre-vulcanized relax modulus (PRM) at 100% is a reliable property to control the pre vulcanization of latex by radiation

  7. Efficiency and Import Penetration on the Productivity of Textile Industry and Textile Products

    Directory of Open Access Journals (Sweden)

    Catur Basuki Rakhmawan

    2012-12-01

    Full Text Available Although textile industry and textile products belong to the strategic sub-sector of manufacturing industry in Indonesia, they are facing problems on the availability of energy, old production machines, and the flooding of imported products into the domestic market. This study is aimed to analyze the efficiency and productivity as performance indicators and how the efficiency and import penetration affect the productivity of textile industry and textile products. The methods of data analysis used in this research are divided in two phases. The first phase, the non-metric approach of Data Envelopment Analysis (DEA is applied to measure the efficiency and productivity. Secondly, the fixed effect model of econometric regression approach is used to find out the effects of efficiency and import penetration on the productivity of textile industry and textile products. The result shows that the average level of efficiency of textile industry and textile products during the period of 2004 – 2008 is about 40 percent with a growth rate of average productivity increases 2.4 percent. Whereas, the econometric estimation results indicate that the increase of efficiency will positively and significantly affect the productivity of textile industry and textile products. On the other hand, the increase of import penetration will negatively affect the productivity of this industry.

  8. Fission products collecting devices

    International Nuclear Information System (INIS)

    Matsumoto, Hiroshi

    1979-01-01

    Purpose: To enable fission products trap with no contamination to coolants and cover gas by the provision of a fission products trap above the upper part of a nuclear power plant. Constitution: Upon fuel failures in a reactor core, nuclear fission products leak into coolants and move along the flow of the coolants to the coolants above the reactor core. The fission products are collected in a trap container and guided along a pipeline into fission products detector. The fission products detector monitors the concentration of the fission products and opens the downstream valve of the detector when a predetermined concentration of the fission products is detected to introduce the fission products into a waste gas processing device and release them through the exhaust pipe. (Seki, T.)

  9. Quality determinants of fruit and vegetables productions

    Directory of Open Access Journals (Sweden)

    Bruno Mezzetti

    2009-04-01

    Full Text Available Nowadays, the main goal for modern horticultural production is the increase of quality. Furthermore, in consideration of the new consumer demand, always more attracted by a diet based on a larger consumption of fruit and vegetables without risks of pesticides residues and with increased nutritional value, new important features in addition to the traditional quality attributes are now requested. For a program of qualification and valorisation of modern horticultural productions, it is fundamental a study of the major quality determinants organized by following a heuristic approache useful to identify the contribution of each factor in defining the quality of the product. The genetic knowledge applied to all available techniques useful for the creation of new genetic variability surely represent the most important starting point for the release of new varieties with increased nutritional quality without limitation in plant productivity. About agronomic practices, new opportunities are offered by the sustainable management of the production factors able to improve the plant-environment interaction, to well address the reduction of inputs needed for the production, and finally to induce specific stress conditions able to promote higher quality at reduced inputs. Much more attention is also addressed to the post-harvest technologies, this because of the increased needs to guarantee the preservation of the high quality obtained in the field until the consumer use. Taking in account such complexity of the horticultural production systems and examples of some major model crops, an outlook of the main determinants and potential valorisation of high quality horticultural products are attempted.

  10. Quality determinants of fruit and vegetables productions

    Directory of Open Access Journals (Sweden)

    Bruno Mezzetti

    Full Text Available Nowadays, the main goal for modern horticultural production is the increase of quality. Furthermore, in consideration of the new consumer demand, always more attracted by a diet based on a larger consumption of fruit and vegetables without risks of pesticides residues and with increased nutritional value, new important features in addition to the traditional quality attributes are now requested. For a program of qualification and valorisation of modern horticultural productions, it is fundamental a study of the major quality determinants organized by following a heuristic approache useful to identify the contribution of each factor in defining the quality of the product. The genetic knowledge applied to all available techniques useful for the creation of new genetic variability surely represent the most important starting point for the release of new varieties with increased nutritional quality without limitation in plant productivity. About agronomic practices, new opportunities are offered by the sustainable management of the production factors able to improve the plant-environment interaction, to well address the reduction of inputs needed for the production, and finally to induce specific stress conditions able to promote higher quality at reduced inputs. Much more attention is also addressed to the post-harvest technologies, this because of the increased needs to guarantee the preservation of the high quality obtained in the field until the consumer use. Taking in account such complexity of the horticultural production systems and examples of some major model crops, an outlook of the main determinants and potential valorisation of high quality horticultural products are attempted.

  11. Urinary incontinence products

    Science.gov (United States)

    ... this page: //medlineplus.gov/ency/article/003973.htm Urinary incontinence products To use the sharing features on this ... There are many products to help you manage urinary incontinence . You can decide which product to choose based ...

  12. Antecedents and Consequences of Reflexivity in New Product Idea Screening

    NARCIS (Netherlands)

    Hammedi, W.; van Riel, A.C.R.; Sasovova, Z.

    2011-01-01

    Pre-development activities, such as new product idea screening, are considered to play an important role in innovation success. At the screening stage, a management team evaluates new product and service ideas and makes a first go/no-go decision under high levels of uncertainty and ambiguity. Paying

  13. Antecedents and Consequences of Reflexivity in New Product Idea Screening

    NARCIS (Netherlands)

    Hammedi, W.; Riel, A.C.R. van; Sasovova, Z.

    2010-01-01

    Pre-development activities, such as new product idea screening, are considered to play an important role in innovation success. At the screening stage, a management team evaluates new product and service ideas and makes a first go/no-go decision under high levels of uncertainty and ambiguity. The

  14. A Phenomenological Examination of Virtual Game Developers' Experiences Using Jacob's Ladder Pre-Production Design Tactic

    Science.gov (United States)

    Brown-Turner, Jasmine

    2017-01-01

    Edutainment refers to curriculum and instruction designed with a clear educational purpose, including multi-faceted virtual learning game design. Tools such as the Jacob's Ladder pre-production design tactic have been developed to ensure that voices of both engineers and educators are heard. However, it is unclear how development team members…

  15. Production control system specified quality sausage products

    Directory of Open Access Journals (Sweden)

    A. V. Tokarev

    2016-01-01

    Full Text Available The problem of management of production target in technological system of production of sausages of the set quality is considered in article. Decomposition of technological system is considered. Functions of management are allocated: formation of an optimum compounding of forcemeat, expert analysis of a compounding, laboratory analysis of a compounding and its statement. Information technology of interaction of these functions is offered. The mathematical problem definition of finding of an optimum compounding meat product with use of possible substitutes of ingredients is presented. This mathematical problem is a classical linear programming problem whose solution has the standard program. Since the manufacture of the finished product are various nonlinear effects are taken into account at the present time it is practically impossible, the methodology provided in this operation "Expert analysis of the formulation" and "Laboratory analysis of the finished product." An example of calculating the optimum alternative base recipe "Sausages “Viennese with cheese”" TS 9213-010-40155161-2002. For an alternative formulation demands were made at a cost of meat, the ingredient composition, as well as the final product organoleptic and physic-chemical indicators should comply with regulatory requirements "Sausages “Viennese with cheese”" TS 9213-010-40155161-2002. Indicator acid activity (pH calculated stuffing formulation should be in the range 6.0-6.3. As a partial replacement for the main raw material have been proposed acceptable substitutes. It was necessary to calculate on the basis of the formulation "Sausages “Viennese with cheese”" TS 9213-010-40155161-2002 optimal price and quality alternative formulation. As a result of depreciation of the value of alternative stuffing recipe was 14,5 % when all of the restrictions on the consumer properties. The proposed information technology implemented in the software package "Multi

  16. PRODUCTION TECHNICS AT GRAPHIC DESIGN EDUCATION AND THE NECCESSITY OF PREPARATION KNOWLEDGE OF PRE-PRINTING

    OpenAIRE

    CEYLAN, İbrahim Gökhan

    2015-01-01

    It is neccessary to teach the knowledge of production technics and pre-printing preparations besides the knowledge of developing creativity and aesthetic concerns in order to educate the designers to fullfill the needs of the sector totally at graphic design education. The printed materials prepared by the graphic designer should be evaluated in proper criterias ıf the materials are to be printed. Graphic designers should have the knowledge of the required knowledge of the area in order to me...

  17. Optimisation of dilute acid pre-treatment of artisan rice hulls for ethanol production

    International Nuclear Information System (INIS)

    Lopez, Yoney; Martin, Carlos; Gullon, Beatriz; Parajo, Juan Carlos

    2011-01-01

    Rice hulls are potential low-cost feedstocks for fuel ethanol production in many countries. In this work, the dilute-acid pre-treatment of artisan rice hulls was investigated using a central composite rotatable experimental design. The experimental variables were temperature (140-210 C), biomass load (5-20%) and sulphuric acid concentration (0.5-1.5 g per 100 g of reaction mixture). A total of 16 experimental runs, including a 23-plan, two replicates at the central point and six star points, were carried out. Low temperatures were found to be favourable for the hydrolysis of xylan and of the easily hydrolyzable glucan fraction. High glucose formation (up to 15.3 g/100 g), attributable to starch hydrolysis, was detected in the hydrolysates obtained under the least severe pre-treatment conditions. Using the experimental results, several models for predicting the effect of the operational conditions on the yield of pretreated solids, xylan and glucan conversion upon pre-treatment, and on enzymatic convertibility of cellulose were developed. Optimum results were predicted for the conversion of easily-hydrolyzable glucan in the material pretreated at 140.7 C, and for the enzymatic saccharification of cellulose in the material pretreated at 169 C. These results suggested the use of two-step acid hydrolysis as future pre-treatment strategy for artisan rice hulls. Key words: Dilute acid hydrolysis, enzymatic hydrolysis, pre-treatment, rice hulls. (author)

  18. All Plasma Products Are Not Created Equal: Characterizing Differences Between Plasma Products

    Science.gov (United States)

    2015-06-01

    Research and the US Department of Defense. The pooling and solvent detergent treatment processes performed to manufacture the Octaplas and Kedrion products ...All plasma products are not created equal: Characterizing differences between plasma products Philip C. Spinella, MD, Elfaridah Frazier, PhD, Heather... products that may affect efficacy and safety. METHODS: Four different plasma products were analyzed to include fresh frozen plasma (FFP), liquid plasma

  19. Comparative study of Fischer–Tropsch production and post-combustion CO2 capture at an oil refinery: Economic evaluation and GHG (greenhouse gas emissions) balances

    International Nuclear Information System (INIS)

    Johansson, Daniella; Franck, Per-Åke; Pettersson, Karin; Berntsson, Thore

    2013-01-01

    The impact on CO 2 emissions of integrating new technologies (a biomass-to-Fischer–Tropsch fuel plant and a post-combustion CO 2 capture plant) with a complex refinery has previously been investigated separately by the authors. In the present study these designs are integrated with a refinery and evaluated from the point-of-view of economics and GHG (greenhouse gas emissions) emissions and are compared to a reference refinery. Stand-alone Fischer–Tropsch fuel production is included for comparison. To account for uncertainties in the future energy market, the assessment has been conducted for different future energy market conditions. For the post-combustion CO 2 capture process to be profitable, the present study stresses the importance of a high charge for CO 2 emission. A policy support for biofuels is essential for the biomass-to-Fischer–Tropsch fuel production to be profitable. The level of the support, however, differs depending on scenario. In general, a high charge for CO 2 economically favours Fischer–Tropsch fuel production, while a low charge for CO 2 economically favours Fischer–Tropsch fuel production. Integrated Fischer–Tropsch fuel production is most profitable in scenarios with a low wood fuel price. The stand-alone alternative shows no profitability in any of the studied scenarios. Moreover, the high investment costs make all the studied cases sensitive to variations in capital costs. - Highlights: • Comparison of Fischer–Tropsch (FT) fuel production and CO 2 capture at a refinery. • Subsidies for renewable fuels are essential for FT fuel production to be profitable. • A high charge for CO 2 is essential for post-combustion CO 2 capture to be profitable. • A low charge for CO 2 economically favours FT fuel production. • Of the studied cases, CO 2 capture shows the greatest reduction in GHG emissions

  20. COMPETITIVE PRODUCT ADVANTAGES

    Directory of Open Access Journals (Sweden)

    Adrian MICU

    2006-01-01

    Full Text Available Cost advantages may be either internal or external. Internal economics of scope, scale, or experience, and external economies of focus or logistical integration, enable a company to produce some products at a lower cost than the competition. The coordination of pricing with suppliers, although not actually economizing resources, can improve the efficiency of pricing by avoiding the incrementalization of a supplier's nonincremental fixed costs and profit. Any of these strategies can generate cost advantages that are, at least in the short run, sustainable. Even cost advantages that are not sustainable, however, can generate temporary savings that are often the key to building more sustainable cost or product advantages later.. Even when a product's physical attributes are not readily differentiable, opportunities to develop product advantages remain. The augmented product that customers buy is more than the particular product or service exchanged. It includes all sorts of ancillary services and intangible relationships that make buying thesame product from one company less difficult, less risky, or more pleasant than buying from a competitor. Superior augmentation of the same basic product can add substantial value in the eyes of consumers, leading them to pay willingly what are often considerable price premiums.

  1. Primary productivity

    Digital Repository Service at National Institute of Oceanography (India)

    Verlecar, X.N.; Parulekar, A.H.

    Photosynthetic production in the oceans in relation to light, nutrients and mixing processes is discussed. Primary productivity in the estuarine region is reported to be high in comparison to coastal and oceanic waters. Upwelling phenomenon...

  2. Technology for production of shelf stable fruit cubes

    International Nuclear Information System (INIS)

    Mishra, B.B.; Jain, M.P.; Sharma, A.

    2009-01-01

    A technology has been developed for the production of intermediate moisture fruit cubes using a combination of osmotic dehydration and infrared drying. Fruits like pineapple, papaya, mango, banana and apple can be successfully converted into intermediate moisture products in the form of fruit cubes using this technology. The fruit cubes can blend very well as natural nutritious supplements with breakfast cereals and in certain food preparations like ice creams, milk shakes, jellies and custards. The product is microbiologically safe for consumption and can be stored at ambient storage condition for more than six months. This technology is an effective alternative for post harvest processing and preservation of ripened fruits. Fruit jam is an additional by-product generated by the process. This technology has been transferred to TT and CD, BARC

  3. Production of carboxylic acid and salt co-products

    Science.gov (United States)

    Hanchar, Robert J.; Kleff, Susanne; Guettler, Michael V.

    2014-09-09

    This invention provide processes for producing carboxylic acid product, along with useful salts. The carboxylic acid product that is produced according to this invention is preferably a C.sub.2-C.sub.12 carboxylic acid. Among the salts produced in the process of the invention are ammonium salts.

  4. Production of 165 Dy for radiation synovectomy, in a low-power (slowpoke) nuclear reactor

    International Nuclear Information System (INIS)

    Bridges, C.; Duke, M.J.M.; McQuarrie, S.A.; Wiebe, L.I.

    1998-01-01

    Full text: Severe, debilitating pain accompanies inflammation of the synovial membrane in rheumatoid arthritis. Under certain conditions, radiation synovectomy is an effective alternative to surgery for relief of these symptoms. Radionuclides which decay by the emission of beta particles, or beta plus low yields of gamma/x-rays are indicated for this medical application. Of the radionuclides with appropriate decay emissions, half-life and physical/chemical properties, 165 Dy is a suitable candidate for production in a low-power reactor. Literature methods for production of this radiopharmaceutical usually involve irradiating solid Dy(OH) 3 , which is dissolved in HCl to form DyCl 3 and then re-precipitated under controlled conditions using NaOH, to produce the desired particle size for medical use. A procedure in which most or all of this post-irradiation processing can be eliminated is particularly important when using low neutron flux reactors, in order to avoid reductions in the amount of deliverable radiopharmaceutical. Radiological safety considerations may also necessitate avoiding post-irradiation processing, since low-power reactor facilities usually have no appropriate hot cells for extensive manipulation of highly active samples. Appropriately-sized, pre-formed Dy(OH) 3 particles were produced under a variety of conditions in attempts to produce a stable, sodium-free product that would be suitable for irradiation and use without further processing. Sodium content could be reduced to about 165 Dy production yields and particle characteristics will be presented in support of this concept

  5. Sustainable aggregates production : green applications for aggregate by-products.

    Science.gov (United States)

    2015-06-01

    Increased emphasis in the construction industry on sustainability and recycling requires production of : aggregate gradations with lower dust (cleaner aggregates) and smaller maximum sizeshence, increased : amount of quarry by-products (QBs). QBs ...

  6. Adopting Product Modularity in House Building to Support Mass Customisation

    Directory of Open Access Journals (Sweden)

    Cecília G. da Rocha

    2015-04-01

    Full Text Available Product modularity is a concept that can contribute to the improvement of product quality and production efficiency in house-building. However, there is a lack of consensus in the literature on the concepts that define product modularity. Furthermore, little attention has been given to the differences between building construction and manufacturing, for which product modularity was originally developed. This research aims to address that gap by adapting the conceptualization of product modularity so that it can effectively be used in the house-building industry. The methodological approach adopted in this study was Design Science Research, and two empirical studies were carried out on construction companies based in Brazil and in the U.K. Those studies are used to illustrate the applicability and utility of the proposed concepts and tools. Research findings indicate that the adoption of product modularity concepts results in benefits to both traditional construction technologies and pre-fabricated building systems.

  7. Product plots.

    Science.gov (United States)

    Wickham, Hadley; Hofmann, Heike

    2011-12-01

    We propose a new framework for visualising tables of counts, proportions and probabilities. We call our framework product plots, alluding to the computation of area as a product of height and width, and the statistical concept of generating a joint distribution from the product of conditional and marginal distributions. The framework, with extensions, is sufficient to encompass over 20 visualisations previously described in fields of statistical graphics and infovis, including bar charts, mosaic plots, treemaps, equal area plots and fluctuation diagrams. © 2011 IEEE

  8. A Conceptual Model for Production Leveling (Heijunka) Implementation in Batch Production Systems

    OpenAIRE

    De Araujo , Luciano Fonseca; De Queiroz , Abelardo Alves

    2009-01-01

    International audience; This paper explains an implementation model for a new method for Production Leveling designed for batch production system. The main structure of this model is grounded on three constructs: traditional framework for Operations Planning, Lean Manufacturing concepts for Production Leveling and case study guidelines. By combining the first and second construct, a framework for Production Leveling has been developed for batch production systems. Then, case study guidelines ...

  9. improving citric acid production from some carbohydrates by-products using irradiated aspergillus niger

    International Nuclear Information System (INIS)

    Farag, S.S.

    2011-01-01

    Twenty strains of A. niger were isolated from different sources, screened for their capacity to produce citric acid. All the isolated strains were able to produce citric acid in different quantities at different time intervals i.e. 4, 8 and 12 days on indicator medium. The best incubation period for production for all isolates was 12 days. The most potent strains for production were A 1 , A 4 and A 5 , while A 8 , A 1 6, A 18 and A 19 recorded weak production on that medium. Citric acid productivity were obtained by all strains when using different concentrations of four carbohydrate by-products (maize straw, potato peel wastes, sugar beet pulp and molasses) when each used alone without any additions after 12 days incubation and the production enhanced when the fermentation medium amended with the same concentrations of the mentioned substrates. Type and concentration of carbohydrate by-product affect the production of citric acid by A. niger strains under the study. Increasing substrate concentration led to increase in production, the best concentration for production was 25% for all carbohydrate by-products. As recorded with indicator medium, A 1 , A 4 and A 5 are also the most potent strains for production when growing on the four carbohydrate by-products supplemented to the basal medium, while A 8 , A 6 , A 18 and A 19 recorded the weak production with the carbohydrate by-products used.production of the parental isolates A 1 , A 4 and A 5 on indicator medium were: 0.96, 0.95 and 0.99 (mg/ml) respectively after 12 days incubation, while maximum production by the obtaining resulting isolates (Treated by UV irradiation) were: 1.78, 1.70 and 1.73 (mg/ml) from A 4 T 2 (5 min.), A 4 T 1 (10 min.) and A 1 T 1 (5 min.), respectively.

  10. Advances in production technology

    CERN Document Server

    2015-01-01

    This edited volume contains the selected papers presented at the scientific board meeting of the German Cluster of Excellence on “Integrative Production Technology for High-Wage Countries”,  held in November 2014. The topical structure of the book is clustered in six sessions: Integrative Production Technology, Individualised Production, Virtual Production Systems, Integrated Technologies, Self-Optimising Production Systems and Human Factors in Production Technology. The Aachen perspective on a holistic theory of production is complemented by conference papers from external leading researchers in the fields of production, materials science and bordering disciplines. The target audience primarily comprises research experts and practitioners in the field but the book may also be beneficial for graduate students.

  11. Exotic nuclei: production, properties and specificity

    International Nuclear Information System (INIS)

    Van Duppen, Piet

    1998-01-01

    In this paper we will put the production of energetic radioactive ion beams of exotic nuclei in perspective and describe the two complementary production processes that are used nowadays: Isotope Separation On-Line (ISOL) followed by post-acceleration, and In-Flight Separation (IFS). After a general description of the process we will focus on recent technical developments in the field. In the subsequent section we give some 'typical' examples of physics cases that are addressed with exotic beams. The examples are chosen not only because their physics importance but also to demonstrate the complementary aspects in the production process and the detection systems. This overview will not be complete and the reader is referred to literature for further information, nor is the lecture intended to give an overview of all the efforts that are taking place in the field by mentioning every project separately. (author)

  12. 48 CFR 552.238-72 - Identification of Products That Have Environmental Attributes.

    Science.gov (United States)

    2010-10-01

    ... buyers to purchase products that are less harmful to the environment, when they are life cycle cost... highlight environmental products under Federal Supply Service schedule contracts in various communications..., and low volatile organic compounds (VOCs). Post-consumer material means a material or finished product...

  13. Human Resource Development for Uranium Production Cycle

    International Nuclear Information System (INIS)

    Ganguly, C.

    2014-01-01

    Concluding Remarks & Suggestions: • HRD will be one of the major challenges in the expanding nuclear power program in countries like China and India. • China and India get uranium raw material from domestic mines and international market. In addition, China has overseas uranium property. India is also exploring the possibility of overseas Joint Venture and uranium properties. For uranium production cycle there is a need for trained geologist, mining engineers, chemical and mechanical engineers. • There is a need for introducing specialization course on “uranium production cycle” at post graduate levels in government and private universities. Overseas Utilities and private firms in India engaged in nuclear power and fuel cycle activities may like to sponsor MTech students with assurance of employment after the successful completion of the course. • The IAEA may consider to extend Technical Assistance to universities in HRD in nuclear power and fuel cycle in general and uranium production cycle in particular - IAEA workshops, with participation of international experts, on uranium geology, mining, milling and safety and best practices in uranium production cycle will be of great help. • The IAEA – UPSAT could play an important role in HRD in uranium production cycle

  14. Smart consumer products with a pathfinder product development strategy

    Science.gov (United States)

    Robertson, Alec

    1994-09-01

    It is generally acknowledged that technologies diffuse through industry and that the rate of diffusion varies both within different industries and according to the circumstances. Innovation is a process involving risk, especially during the adoption and adaptation of a powerful new technology. Central to a consumer products success using new technology is the quality of their designs and the nature of their forms. Form is of prime importance in influencing the purchasing decisions of consumers and it is also influential in determining the relationships between people in its use environment. The acceptance of a new product into the world is often unduly ad hoc. Many failures are created for each success and there are few guidelines to assist the formulation of a strategy for creating an appropriate form. It is suggested below that success of consumer products incorporating 'smart structures' may be determined not only by the function of products and systems, but also by the form they take. The definition of a desirable product form depends entirely on the point of view taken: technological, commercial, ecological, cultural, and social. However any design using new will incorporate the old and the new. The probability of acceptance of a new product is enhanced by maintaining a fine balance between imaginative and creative form and that with which people are familiar and prefer: a new design may be rejected if it is too novel and unfamiliar, or too traditional. The acceptance of a new product and its subsequent development depends on the success designers and engineers have when dealing with the initial forms, particularly using new technology such as 'smart structures'.

  15. Dairy product consumption is associated with pre-diabetes and newly diagnosed type 2 diabetes in the Lifelines Cohort Study

    NARCIS (Netherlands)

    Brouwer, E.M.; Sluik, D.; Singh-Povel, C.M.; Feskens, E.J.M.

    2018-01-01

    Previous studies show associations between dairy product consumption and type 2 diabetes, but only a few studies conducted detailed analyses for a variety of dairy subgroups. Therefore, we examined cross-sectional associations of a broad variety of dairy subgroups with pre-diabetes and newly

  16. Polling, production & priorities

    NARCIS (Netherlands)

    Winands, E.M.M.

    2007-01-01

    Polling, Production & Priorities The present monograph focuses on the so-called stochastic economic lot scheduling problem (SELSP), which deals with the make-to-stock production of multiple standardized products on a single machine with limited capacity under random demands, possibly random setup

  17. Composting plant conversion for the production of bio based products; Konversion eines Kompostwerkes zur Herstellung biobasierter Produkte

    Energy Technology Data Exchange (ETDEWEB)

    Hoffmann, Marc [Universitaetsklinikum Jena (Germany). Stabsstelle Umweltschutz

    2013-03-15

    The intention behind this paper is to explore the potential of extracting bio based products such as lactic acid and further organic acid compounds during a successful composting process, by inserting an additional pre-treatment level into the existing process. The fundamental idea of extracting bio based products and biogas is based on the extension of a composting plant with an anaerobic intermediate level of maceration and a bypass reactor as a potential bio-refinery. For the extraction of carboxylic acid out of the macerated substance the principle of electrodialysis on a laboratory scale can be successfully verified by means of concentration of free acids. The concluding assessment of the composting plant Darmstadt-Kranichstein with regards to its potential shows that further examination on a large scale for the extraction of biobased products using biowaste is deemed to be appropriate on material and energetic consideration. The study demonstrates the potential for a combined aerobic/anaerobic plant with composting, renewable energy and secondary raw materials generation. (orig.)

  18. Production of highly unsaturated fatty acids using agro-processing by-products

    CSIR Research Space (South Africa)

    Jacobs, A

    2008-11-01

    Full Text Available The South African agro-processing industry generates millions of tons of cereal derived by-products annually. The by-products from biofuel production are expected to increase these volumes dramatically. Highly unsaturated fatty acids (HUFA...

  19. Evaluating the Impact of a New Product on the Sales of other Products

    OpenAIRE

    Julian Andreev Vasilev

    2014-01-01

    The purpose of this article is to evaluate the impact of a new product on the sales of other products. Launching a new product may lead to increase or decrease of sales in the products of the same group. Customers may continue buying standard products or they may be oriented to new products. New products may cause internal competition. Statistical methods are applied. Time series analysis is used. Transactional database of a confectionary factory is the main source of data. The time series an...

  20. MANAGING PRODUCT SAFETY SYSTEM HACCP ON THE EXAMPLE OF BEET-SUGAR PRODUCTION

    Directory of Open Access Journals (Sweden)

    V. A. Golybin

    2015-01-01

    Full Text Available The most effective safety management system of food production in all industrialized countries in the world recognized by the system based on the principles of HACCP. In Russia, the conformity assessment carried out by the HACCP system certification. The essence of the HACCP system is to identify and control the critical points. Critical Control Point – this is the stage of the process, which is subject to control for hazard identification and risk management in order to avoid the production of unsafe products. Implementation of HACCP system allows to tighten and coordinate the quality control system, which will improve the competitiveness of the products produced in the sugar market in Russia and abroad. In the early stages of food production HACCP system to prevent the occurrence of danger. It is based on the preventive approach to ensuring quality and safety in the production process, and can also be used in the development of new products. HACCP system is based on seven main principles to ensure the implementation and management of the system in production. 1. Creation of a working group of the coordinator and the technical secretary and various consultants. 2. Information on materials and products, in this case of sugar beet and sugar. 3. Information about the production. 4. Risk analysis of the available chemical, physical and microbiological factors. To determine the critical control points according to the results obtained for each factor is determined by a special chart the extent of its accounting. The need to consider the potential hazard is determined by the order in which area it has got. 5. The production program of mandatory preliminary activities in the production of sugar. 6. Determination of critical control points. 7. Making worksheets HACCP. It is shown that the use of HACCP in sugar beet production has several advantages.

  1. The Virtual Product-Process Design Laboratory for Structured Chemical Product Design and Analysis

    DEFF Research Database (Denmark)

    Mattei, Michele; Yunus, Nor Alafiza Binti; Kalakul, Sawitree

    2014-01-01

    The objective of this paper is to present new methods for design of chemicals based formulated products and their implementation in the software, the Virtual Product-Process Design Laboratory. The new products are tailor-made blended liquid products and emulsion-based products. The new software...

  2. Modeling intermediate product selection under production and storage capacity limitations in food processing

    DEFF Research Database (Denmark)

    Kilic, Onur Alper; Akkerman, Renzo; Grunow, Martin

    2009-01-01

    In the food industry products are usually characterized by their recipes, which are specified by various quality attributes. For end products, this is given by customer requirements, but for intermediate products, the recipes can be chosen in such a way that raw material procurement costs and pro...... with production and inventory planning, thereby considering the production and storage capacity limitations. The resulting model can be used to solve an important practical problem typical for many food processing industries.......In the food industry products are usually characterized by their recipes, which are specified by various quality attributes. For end products, this is given by customer requirements, but for intermediate products, the recipes can be chosen in such a way that raw material procurement costs...... and processing costs are minimized. However, this product selection process is bound by production and storage capacity limitations, such as the number and size of storage tanks or silos. In this paper, we present a mathematical programming approach that combines decision making on product selection...

  3. Production Leveling (Heijunka) Implementation in a Batch Production System: A Case Study

    OpenAIRE

    Araujo , Luciano Fonseca; Queiroz , Abelardo Alves

    2009-01-01

    International audience; This paper presents a case study of an implementation of a new method for Production Leveling designed for batch production. It includes prioritizing criteria of products and level production plan. Moreover, it was applied on a subsidiary of a multinational enterprise located on Brazil, which manufacturing processes comprise batch production in a make-to-stock policy. Regarding a qualitative assessment, evidences show that the company had deficient practices related to...

  4. Economic Feasibility of Functional Meat Products for Commercial Production in India

    Directory of Open Access Journals (Sweden)

    Varalakshmi Kandanuri

    2017-07-01

    Full Text Available This paper analyses the production of functional chicken meat products from economic perspectives. It analyses and compares the economics and investment feasibility on different size groups of processing plants in India. The primary data on input use and output yield were taken from studies of NRCM and data was analysed using economic analysis and investment appraisal techniques like NPV, IRR(%, BC ratio, and Break even analysis. The results indicated that the cost of production of functional products was 5.2 and 5.18 and 4.59 US dollars per kg on small, medium and large scale units respectively. All the processing units are found to be economically feasible with NPV of US$ 12727, 64661 and 153703, IRR of 26%,31% and 42% and B-C ratio was estimated as 1.56, 1.78 and 2.29 for small, medium and large scale units respectively. Economies of scale is evident form all perspectives like production costs, profits, discounting measures and breakeven point. The study found the feasibility of functional meat products in India for commercial production.

  5. Ergonomic Product Design 21

    International Nuclear Information System (INIS)

    Kwon, Yeong Guk

    1996-09-01

    This book explains basic of ergonomic product design with human engineering, image engineering and strategy of that design, ergonomic industrial design, which includes product design to access the human engineering in development of new product and customer satisfaction, application technology of image engineering, industrial design of human engineering item and strategy of human engineering, a good ergonomic design. It also tells of examples of convenient design for human such as hardware product and software product in automobile, telephones for ergonomic product in the future, new goods and new technology, ergonomic product in house and office, and computers and robots in the future.

  6. Optimal Product Placement.

    Science.gov (United States)

    Hsu, Chia-Ling; Matta, Rafael; Popov, Sergey V; Sogo, Takeharu

    2017-01-01

    We model a market, such as an online software market, in which an intermediary connects sellers and buyers by displaying sellers' products. With two vertically-differentiated products, an intermediary can place either: (1) one product, not necessarily the better one, on the first page, and the other hidden on the second page; or (2) both products on the first page. We show that it can be optimal for the intermediary to obfuscate a product-possibly the better one-since this weakens price competition and allows the sellers to extract a greater surplus from buyers; however, it is not socially optimal. The choice of which one to obfuscate depends on the distribution of search costs.

  7. Thermophilic Biohydrogen Production

    DEFF Research Database (Denmark)

    Karakashev, Dimitar Borisov; Angelidaki, Irini

    2011-01-01

    Dark fermentative hydrogen production at thermophilic conditions is attractive process for biofuel production. From thermodynamic point of view, higher temperatures favor biohydrogen production. Highest hydrogen yields are always associated with acetate, or with mixed acetate- butyrate type...... fermentation. On the contrary the hydrogen yield decreases, with increasing concentrations of lactate, ethanol or propionate. Major factors affecting dark fermentative biohydrogen production are organic loading rate (OLR), pH, hydraulic retention time (HRT), dissolved hydrogen and dissolved carbon dioxide...... concentrations, and soluble metabolic profile (SMP). A number of thermophilic and extreme thermophilic cultures (pure and mixed) have been studied for biohydrogen production from different feedstocks - pure substrates and waste/wastewaters. Variety of process technologies (operational conditions...

  8. Effect of thermal, chemical and thermo-chemical pre-treatments to enhance methane production

    Energy Technology Data Exchange (ETDEWEB)

    Rafique, Rashad; Nizami, Abdul-Sattar; Murphy, Jerry D.; Kiely, Gerard [Department of Civil and Environmental Engineering, University College Cork (Ireland); Poulsen, Tjalfe Gorm [Department of Biotechnology, Chemistry and Environmental Engineering, Aalborg University (Denmark); Asam, Zaki-ul-Zaman [Department of Civil Engineering, National University of Ireland Galway (Ireland)

    2010-12-15

    The rise in oil price triggered the exploration and enhancement of various renewable energy sources. Producing biogas from organic waste is not only providing a clean sustainable indigenous fuel to the number of on-farm digesters in Europe, but also reducing the ecological and environmental deterioration. The lignocellulosic substrates are not completely biodegraded in anaerobic digesters operating at commercial scale due to their complex physical and chemical structure, which result in meager energy recovery in terms of methane yield. The focus of this study is to investigate the effect of pre-treatments: thermal, thermo-chemical and chemical pre-treatments on the biogas and methane potential of dewatered pig manure. A laboratory scale batch digester is used for these pre-treatments at different temperature range (25 C-150 C). Results showed that thermo-chemical pretreatment has high effect on biogas and methane potential in the temperature range (25-100 C). Maximum enhancement is observed at 70 C with increase of 78% biogas and 60% methane production. Thermal pretreatment also showed enhancement in the temperature range (50-10 C), with maximum enhancement at 100 C having 28% biogas and 25% methane increase. (author)

  9. Production planning of a perishable product with lead time and non-stationary demand

    NARCIS (Netherlands)

    Pauls-Worm, K.G.J.; Haijema, R.; Hendrix, E.M.T.; Rossi, R.; Vorst, van der J.G.A.J.

    2012-01-01

    We study a production planning problem for a perishable product with a fixed lifetime, under a service-level constraint. The product has a non-stationary stochastic demand. Food supply chains of fresh products like cheese and several crop products, are characterised by long lead times due to

  10. Validation of Product Properties Considering a High Variety of Complex Products

    OpenAIRE

    Kortler, S.;Kohn, A.;Lindemann, U.

    2017-01-01

    Validation processes are becoming more and more complex. Due to rising technical capabilities and a wide variety of customer requirements, OEMs are increasing their product variety in order to increase profits. According to the various characteristics of subcontracted components involved in complex products, the product variety can be very high. The impacts of the involved subcontracted components on the composed product variety during the product’s application are difficult to predict. This ...

  11. miR-2861 as novel HDAC5 inhibitor in CHO cells enhances productivity while maintaining product quality.

    Science.gov (United States)

    Fischer, Simon; Paul, Albert Jesuran; Wagner, Andreas; Mathias, Sven; Geiss, Melanie; Schandock, Franziska; Domnowski, Martin; Zimmermann, Jörg; Handrick, René; Hesse, Friedemann; Otte, Kerstin

    2015-10-01

    Histone deacetylase (HDAC) inhibitors have been exploited for years to improve recombinant protein expression in mammalian production cells. However, global HDAC inhibition is associated with negative effects on various cellular processes. microRNAs (miRNAs) have been shown to regulate gene expression in almost all eukaryotic cell types by controlling entire cellular pathways. Since miRNAs recently have gained much attention as next-generation cell engineering tool to improve Chinese hamster ovary (CHO) cell factories, we were interested if miRNAs are able to specifically repress HDAC expression in CHO cells to circumvent limitations of unspecific HDAC inhibition. We discovered a novel miRNA in CHO cells, miR-2861, which was shown to enhance productivity in various recombinant CHO cell lines. Furthermore, we demonstrate that miR-2861 might post-transcriptionally regulate HDAC5 in CHO cells. Intriguingly, siRNA-mediated HDAC5 suppression could be demonstrated to phenocopy pro-productive effects of miR-2861 in CHO cells. This supports the notion that miRNA-induced inhibition of HDAC5 may contribute to productivity enhancing effects of miR-2861. Furthermore, since product quality is fundamental to safety and functionality of biologics, we examined the effect of HDAC inhibition on critical product quality attributes. In contrast to unspecific HDAC inhibition using VPA, enforced expression of miR-2861 did not negatively influence antibody aggregation or N-glycosylation. Our findings highlight the superiority of miRNA-mediated inhibition of specific HDACs and present miR-2861 as novel cell engineering tool for improving CHO manufacturing cells. © 2015 Wiley Periodicals, Inc.

  12. POSSIBILITIES OF INCREASING EFFICIENCY WITHIN SERIAL PRODUCTION MANAGEMENT

    Directory of Open Access Journals (Sweden)

    CODRUŢA DURA

    2010-01-01

    Full Text Available Under the impact of transition to the new post-industrial society, massproduction recently faced the most numerous difficulties. They are caused by turbulences in theexternal environment in which companies operate, manifested in particular by enhancing thedynamism of markets and by deep changes in the structure of consumers’ demands. In thiscontext, specialized literature records the concerns for increasing the efficiency and flexibilityof products, elements involving radical changes of management and manufacturingtechnologies methods. Given these issues, the paper approaches two separate ways to improvethe management of serial production: increasing economic efficiency by optimizing the size ofbatches and flexible production systems by implementing techniques to reduce the change-overtime.

  13. Enriching step-based product information models to support product life-cycle activities

    Science.gov (United States)

    Sarigecili, Mehmet Ilteris

    The representation and management of product information in its life-cycle requires standardized data exchange protocols. Standard for Exchange of Product Model Data (STEP) is such a standard that has been used widely by the industries. Even though STEP-based product models are well defined and syntactically correct, populating product data according to these models is not easy because they are too big and disorganized. Data exchange specifications (DEXs) and templates provide re-organized information models required in data exchange of specific activities for various businesses. DEXs show us it would be possible to organize STEP-based product models in order to support different engineering activities at various stages of product life-cycle. In this study, STEP-based models are enriched and organized to support two engineering activities: materials information declaration and tolerance analysis. Due to new environmental regulations, the substance and materials information in products have to be screened closely by manufacturing industries. This requires a fast, unambiguous and complete product information exchange between the members of a supply chain. Tolerance analysis activity, on the other hand, is used to verify the functional requirements of an assembly considering the worst case (i.e., maximum and minimum) conditions for the part/assembly dimensions. Another issue with STEP-based product models is that the semantics of product data are represented implicitly. Hence, it is difficult to interpret the semantics of data for different product life-cycle phases for various application domains. OntoSTEP, developed at NIST, provides semantically enriched product models in OWL. In this thesis, we would like to present how to interpret the GD & T specifications in STEP for tolerance analysis by utilizing OntoSTEP.

  14. Engineering microbial cell factories for the production of plant natural products: from design principles to industrial-scale production.

    Science.gov (United States)

    Liu, Xiaonan; Ding, Wentao; Jiang, Huifeng

    2017-07-19

    Plant natural products (PNPs) are widely used as pharmaceuticals, nutraceuticals, seasonings, pigments, etc., with a huge commercial value on the global market. However, most of these PNPs are still being extracted from plants. A resource-conserving and environment-friendly synthesis route for PNPs that utilizes microbial cell factories has attracted increasing attention since the 1940s. However, at the present only a handful of PNPs are being produced by microbial cell factories at an industrial scale, and there are still many challenges in their large-scale application. One of the challenges is that most biosynthetic pathways of PNPs are still unknown, which largely limits the number of candidate PNPs for heterologous microbial production. Another challenge is that the metabolic fluxes toward the target products in microbial hosts are often hindered by poor precursor supply, low catalytic activity of enzymes and obstructed product transport. Consequently, despite intensive studies on the metabolic engineering of microbial hosts, the fermentation costs of most heterologously produced PNPs are still too high for industrial-scale production. In this paper, we review several aspects of PNP production in microbial cell factories, including important design principles and recent progress in pathway mining and metabolic engineering. In addition, implemented cases of industrial-scale production of PNPs in microbial cell factories are also highlighted.

  15. Oregon's forest products industry: 1994.

    Science.gov (United States)

    Franklin R. Ward

    1997-01-01

    This report presents the findings of a survey of primary forest products industries in Oregon for 1994. The survey included the following sectors: lumber; veneer; pulp and board; shake and shingle; export; and post, pole, and piling. Tables, presented by sector and for the industry as a whole, include characteristics of the industry, nature and flow of logs consumed,...

  16. CONSIDERATIONS UPON MILK AND DAIRY PRODUCT PRODUCTION IN THE U.S.A.

    Directory of Open Access Journals (Sweden)

    AGATHA POPESCU

    2008-05-01

    Full Text Available The paper aimed to present the evolution of milk production and dairy products in the USA during the period 2004-2006, based on USDA Statistics. The USA is a top produce of milk and dairy products in the world. Milk production accounted for 181,798 Millions Pounds in the year 2006. Its continuously increase during the last years has been positively influenced by the increasing number of dairy cows and average milk yield . The top states are California, Wisconsin, New York, Idaho and Pennsylvania, which all together achieve about 54 % of the country milk production. Over 99.37 % of Milk Production is marketed. Considering all milk marketings, Million USD 23,422 cash receiptscould be obtained from a dairy farm in the year 2006. The average return per Cwt was about USD 13 in 2006 . Milk is processed by about 1,000 manufacturing plants in a large variety of dairy products. Cheese production was about 9.5 Billion Pounds in the last analyzed years. The US also produces important amounts of butter , yogurt, ice cream etc. About 8.3 % of the US dairy products are exported, the most markets being Japan, Mexico and Canada.

  17. How companies embed non-quantifiable product qualities through their product development process

    OpenAIRE

    Guldbrandsen, Marianne Norden

    2006-01-01

    Many consumer products have reached a high level of technical product quality. Rapid adoption of new technologies and access to a global market means that markets are getting saturated. This means that technical differentiation is often not enough to sell a product and products compete more and more on intangible product qualities - these are meant to delight, bring pleasure, be easy to use and to create an experience. These qualities are often difficult to measure in the pr...

  18. Sugar-Based Ethanol Biorefinery: Ethanol, Succinic Acid and By-Product Production

    Energy Technology Data Exchange (ETDEWEB)

    Donal F. Day

    2009-03-31

    The work conducted in this project is an extension of the developments itemized in DE-FG-36-04GO14236. This program is designed to help the development of a biorefinery based around a raw sugar mill, which in Louisiana is an underutilized asset. Some technical questions were answered regarding the addition of a biomass to ethanol facility to existing sugar mills. The focus of this work is on developing technology to produce ethanol and valuable by-products from bagasse. Three major areas are addressed, feedstock storage, potential by-products and the technology for producing ethanol from dilute ammonia pre-treated bagasse. Sugar mills normally store bagasse in a simple pile. During the off season there is a natural degradation of the bagasse, due to the composting action of microorganisms in the pile. This has serious implications if bagasse must be stored to operate a bagasse/biorefinery for a 300+ day operating cycle. Deterioration of the fermentables in bagasse was found to be 6.5% per month, on pile storage. This indicates that long term storage of adequate amounts of bagasse for year-round operation is probably not feasible. Lignin from pretreatment seemed to offer a potential source of valuable by-products. Although a wide range of phenolic compounds were present in the effluent from dilute ammonia pretreatment, the concentrations of each (except for benzoic acid) were too low to consider for extraction. The cellulosic hydrolysis system was modified to produce commercially recoverable quantities of cellobiose, which has a small but growing market in the food process industries. A spin-off of this led to the production of a specific oligosaccharide which appears to have both medical and commercial implications as a fungal growth inhibitor. An alternate use of sugars produced from biomass hydrolysis would be to produce succinic acid as a chemical feedstock for other conversions. An organism was developed which can do this bioconversion, but the economics of

  19. Product Configuration Systems and Consequences for Productivity and Quality

    DEFF Research Database (Denmark)

    Pedersen, Jørgen Lindgaard; Edwards, Kasper

    2004-01-01

    with informations about expected and realised costs and benefits in implemented PCS's we have the following results: the three highest aggregated scoring expected benefits are: 1)improved quality in specifications, 2)lower turnaround time, and 3)using less resources.The results achieved are in accordance......Product Configuration Systems (PCS) are systems to produce quotations to potential buyers of the products an enterprise produces. Typically the products are complex and will first be produced according to specific needs from the customers. From twelve case studies in Danish industry...

  20. Implementation effect of productive 4-stage field orientation on the student technopreneur skill in vocational schools

    Science.gov (United States)

    Ismail, Edy; Samsudi, Widjanarko, Dwi; Joyce, Peter; Stearns, Roman

    2018-03-01

    This model integrates project base learning by creating a product based on environmental needs. The Produktif Orientasi Lapangan 4 Tahap (POL4T) combines technical skills and entrepreneurial elements together in the learning process. This study is to implement the result of technopreneurship learning model development which is environment-oriented by combining technology and entrepreneurship components on Machining Skill Program. This study applies research and development design by optimizing experimental subject. Data were obtained from questionnaires, learning material validation, interpersonal, intrapersonal observation forms, skills, product, teachers and students' responses, and cognitive tasks. Expert validation and t-test calculation are applied to see how effective POL4T learning model. The result of the study is in the form of 4 steps learning model to enhance interpersonal and intrapersonal attitudes, develop practical products which orient to society and appropriate technology so that the products can have high selling value. The model is effective based on the students' post test result, which is better than the pre-test. The product obtained from POL4T model is proven to be better than the productive learning. POL4T model is recommended to be implemented for XI grade students. This is can develop entrepreneurial attitudes that are environment oriented, community needs and technical competencies students.

  1. Biodiesel production using oil from fish canning industry wastes

    International Nuclear Information System (INIS)

    Costa, J.F.; Almeida, M.F.; Alvim-Ferraz, M.C.M.; Dias, J.M.

    2013-01-01

    Highlights: • A process was established to produce biodiesel from fish canning industry wastes. • Biodiesel production was enabled by an acid esterification pre-treatment. • Optimization studies showed that the best catalyst concentration was 1 wt.% H 2 SO 4 . • There was no advantage when a two-step alkali transesterification was employed. • Waste oil from olive oil bagasse could be used to improve fuel quality. - Abstract: The present study evaluated biodiesel production using oil extracted from fish canning industry wastes, focusing on pre-treatment and reaction conditions. Experimental planning was conducted to evaluate the influence of acid catalyst concentration (1–3 wt.% H 2 SO 4 ) in the esterification pre-treatment and the amount of methanolic solution (60–90 vol.%) used at the beginning of the further two-step alkali transesterification reaction. The use of a raw-material mixture, including waste oil obtained from olive oil bagasse, was also studied. The results from experimental planning showed that catalyst concentration mostly influenced product yield and quality, the best conditions being 1 wt.% catalyst and 60 vol.% of methanolic solution, to obtain a product yield of 73.9 wt.% and a product purity of 75.5 wt.%. Results from a one-step reaction under the selected conditions showed no advantage of performing a two-step alkali process. Although under the best conditions several of the biodiesel quality parameters were in agreement with standard specifications, a great variation was found in the biodiesel acid value, and oxidation stability and methyl ester content did not comply with biodiesel quality standards. Aiming to improve fuel quality, a mixture containing 80% waste olive oil and 20% of waste fish oil was evaluated. Using such mixture, biodiesel purity increased around 15%, being close to the standard requirements (96.5 wt.%), and the oxidation stability was in agreement with the biodiesel quality standard values (⩾6 h), which

  2. Removal of inhibitors from pre-hydrolysis liquor of kraft-based dissolving pulp production process using adsorption and flocculation processes.

    Science.gov (United States)

    Liu, Xin; Fatehi, Pedram; Ni, Yonghao

    2012-07-01

    A process for removing inhibitors from pre-hydrolysis liquor (PHL) of a kraft-based dissolving pulp production process by adsorption and flocculation, and the characteristics of this process were studied. In this process, industrially produced PHL was treated with unmodified and oxidized activated carbon as an absorbent and polydiallyldimethylammonium chloride (PDADMAC) as a flocculant. The overall removal of lignin and furfural in the developed process was 83.3% and 100%, respectively, while that of hemicelluloses was 32.7%. These results confirmed that the developed process can remove inhibitors from PHL prior to producing value-added products, e.g. ethanol and xylitol via fermentation. Copyright © 2012 Elsevier Ltd. All rights reserved.

  3. Simulation Study of a Vehicle Production Line for Productivity Improvement

    Directory of Open Access Journals (Sweden)

    M.F.F. Ab Rashid

    2015-06-01

    Full Text Available This paper presents the study of a motorcycle frame production line in a particular company in Malaysia. Due to the high demand, the company needs to increase its production by at least 12% compared with current output. In order to improve productivity, the production-floor data was collected and simulated using the discrete event simulation approach. Later, a number of suggestions for improvement were simulated to identify the effect of the suggestions on productivity. In addition, cost analysis was also undertaken to identify the profit margin for a particular period of time for each suggestion. Simulation results indicate that there are three suggestions that are able to fulfill the 12% volume increment. In the short term, the suggestion to hire an assistant line leader will give instant effect to the profit. Meanwhile, for the medium term, Poka-yoke will give higher profit compared with the others, while in the long term, SOP (standard operating procedure implementation will yield a better profit margin. In future, the simulation of a dynamic demand model for this product is suggested to cope with new trends in the market.

  4. Performance optimization of the Växtkraft biogas production plant

    International Nuclear Information System (INIS)

    Thorin, Eva; Lindmark, Johan; Nordlander, Eva; Odlare, Monica; Dahlquist, Erik; Kastensson, Jan; Leksell, Niklas; Pettersson, Carl-Magnus

    2012-01-01

    Highlights: ► Pre-treatment of ley crop can increase the biogas plant performance. ► Membrane filtration can increase the capacity of the biogas plant. ► Mechanical pre-treatment of the ley crop shows the highest energy efficiency. ► Using a distributor to spread the residues as fertilizer show promising results. -- Abstract: All over the world there is a strong interest and also potential for biogas production from organic residues as well as from different crops. However, to be commercially competitive with other types of fuels, efficiency improvements of the biogas production process are needed. In this paper, results of improvements studies done on a full scale co-digestion plant are presented. In the plant organic wastes from households and restaurants are mixed and digested with crops from pasture land. The areas for improvement of the plant addressed in this paper are treatment of the feed material to enhance the digestion rate, limitation of the ballast of organics in the water stream recirculated in the process, and use of the biogas plant residues at farms. Results from previous studies on pre-treatment and membrane filtration of recirculated process water are combined for an estimation of the total improvement potential. Further, the possibility of using neural networks to predict biogas production using historical data from the full-scale biogas plant was investigated. Results from an investigation using the process residues as fertilizer are also presented. The results indicate a potential to increase the biogas yield from the process with up to over 30% with pre-treatment of the feed and including membrane filtration in the process. Neural networks have the potential to be used for prediction of biogas production. Further, it is shown that the residues from biogas production can be used as fertilizers but that the emission of N 2 O from the fertilized soil is dependent on the soil type and spreading technology.

  5. Principles and practices of lean production applied in a metal structures production system

    OpenAIRE

    Carvalho, Rogério; Alves, Anabela Carvalho; Lopes, Isabel da Silva

    2011-01-01

    This paper presents a work undertaken in a metal structures production system in a company producing several assorted products for the civil construction. The work aim was to improve the production process, solving several productive problems encountered in the production system, such as: deliveries delays, long lead times, too many material handling, high stocks, errors and defects in metal structures assembly and production, and unnecessary motions. The identified problems were analyzed and...

  6. Process optimization of large-scale production of recombinant adeno-associated vectors using dielectric spectroscopy.

    Science.gov (United States)

    Negrete, Alejandro; Esteban, Geoffrey; Kotin, Robert M

    2007-09-01

    A well-characterized manufacturing process for the large-scale production of recombinant adeno-associated vectors (rAAV) for gene therapy applications is required to meet current and future demands for pre-clinical and clinical studies and potential commercialization. Economic considerations argue in favor of suspension culture-based production. Currently, the only feasible method for large-scale rAAV production utilizes baculovirus expression vectors and insect cells in suspension cultures. To maximize yields and achieve reproducibility between batches, online monitoring of various metabolic and physical parameters is useful for characterizing early stages of baculovirus-infected insect cells. In this study, rAAVs were produced at 40-l scale yielding ~1 x 10(15) particles. During the process, dielectric spectroscopy was performed by real time scanning in radio frequencies between 300 kHz and 10 MHz. The corresponding permittivity values were correlated with the rAAV production. Both infected and uninfected reached a maximum value; however, only infected cell cultures permittivity profile reached a second maximum value. This effect was correlated with the optimal harvest time for rAAV production. Analysis of rAAV indicated the harvesting time around 48 h post-infection (hpi), and 72 hpi produced similar quantities of biologically active rAAV. Thus, if operated continuously, the 24-h reduction in the production process of rAAV gives sufficient time for additional 18 runs a year corresponding to an extra production of ~2 x 10(16) particles. As part of large-scale optimization studies, this new finding will facilitate the bioprocessing scale-up of rAAV and other bioproducts.

  7. GROWTH PERFORMANCE AND PRODUCTIVITY OF RUBBER & PLASTIC PRODUCTS INDUSTRY IN PUNJAB

    Directory of Open Access Journals (Sweden)

    GULSHAN KUMAR

    2010-01-01

    Full Text Available Present study is an endeavour to investigate growth pattern and productivity trends in small scale rubber and plastic products industry of Punjab. The growth of industry has been gauged in terms of variables - number of units, fixed investment, employment and production. Yearly growth rates have been computed to catch year- to- year fluctuations in growth and compound annual growth rates (CAGRs have been worked out to ascertain the impact of the policies of liberalized regime on growth of this industry. Productivity trends have been sketched in terms of partial factor productivities of labour and capital. In order to understand the strengths and weaknesses of the industry, SWOT analysis has been conducted. The study revealed that the liberalisation has promoted the use of capital intensive and labour saving techniques of production leading to a dismal growth of employment and sluggish growth of number of units.

  8. Energy consumption restricted productivity re-estimates and industrial sustainability analysis in post-reform China

    International Nuclear Information System (INIS)

    Chen, Shiyi; Santos-Paulino, Amelia U.

    2013-01-01

    This paper investigates the impact of energy on China's industrial sustainability by using a novel approach to estimate real total factor productivity. The growth accounting indicates that the substantial industrial reforms in China have led to productivity growth. Energy and capital are also important factors driving China's industrial growth. Productivity growth in China's industry is mostly attributable to the high-tech light industrial sectors. - Highlights: ► Productivity has become the most important growth engine in majority of sectors. ► Energy and capital are also important factors promoting China's industrial growth. ► The productivity improvement is more attributable to high-tech light industry. ► The heavy industry performs worse than the light one in terms of productivity

  9. Health products inspection

    International Nuclear Information System (INIS)

    Stoltz, M.

    2009-01-01

    To protect public health, the Health Products Inspection is a public service mission where the application of regulations concerning activities on human health products and cosmetic products is verified. This mission permits a global approach to assess the health products risk-based benefit and, in monitoring by laboratory testing and by on site inspections, to verify their compliance with appropriate regulations. The seventy five inspectors perform about eight hundred inspections per year, in France and abroad. These inspections are related to data provided in the health products assessment and also to manufacturing and delivery practices. The French inspection body is also involved in the training of foreign inspectors and in the harmonization of national, European and international practices either for operators than for the competent authorities. (author)

  10. Chemical Product Design

    DEFF Research Database (Denmark)

    Gani, Rafiqul

    2004-01-01

    This paper highlights for a class of chemical products, the design process, their design with respect to the important issues, the need for appropriate tools and finally, lists some of the challenges and opportunities for the process systems engineering (PSE)/computer-aided process engineering...... (CAPE) community. The chemical products considered belong to the following types: chemical/biochemical/agrochemical products, coatings and solvents, food (nutraceuticals), HIM (household, industrial and institutional), personal care, pharmaceuticals and drugs. The challenges and opportunities...... are highlighted in terms of the needs for multi-level modeling with emphasis on property models that are suitable for computer-aided applications, flexible solution strategies that are able to solve a large range of chemical product design problems and finally, a systems chemical product design framework...

  11. Production and economic characteristics of sheep production on the island of Pag

    Directory of Open Access Journals (Sweden)

    Marina Krvavica

    2012-03-01

    Full Text Available The aim of the research was to learn from a survey about the production and economic characteristics of sheep production as well as economic position and developmental orientation of sheep breeders on the island of Pag. Data on production and economic characteristics of sheep production on the island of Pag were collected from a survey and processed through relevant descriptive statistics methods. The respondents have on average 47 breeding sheep, 2 rams and 9 sheep intended for flock renewal rate (not older than one year; which means an average flock has 58 sheep. The average total income from sheep production in 2009 was 72,460.10 HRK. The average total production costs in 2009 were 13,260.10 HRK, including the costs of fodder and veterinary services. All farms achieved positive financial results of 59,199.90 HRK in average. As many as three quarters of respondents indicated profitability of sheep production as the main motivation to engage in sheep production; very few indicated that heritage and inability to do other jobs were the main motivation. Important limiting factors for future development of sheep breeding on the island of Pag in most farms are lack of potential heirs and high average age of farm holders. Regarding the effects of joining the European Union, half the breeders intend to improve their production and harmonise it with the EU requirements and standards; one quarter of them intend to keep the existing production capacity; and another quarter intend to quit with production.

  12. Knowledge and acceptability of alternative HIV prevention bio-medical products among MSM who bareback.

    Science.gov (United States)

    Nodin, N; Carballo-Diéguez, A; Ventuneac, A M; Balan, I C; Remien, R

    2008-01-01

    Condom use is the best available strategy to prevent HIV infection during sexual intercourse. However, since many people choose not to use condoms in circumstances in which HIV risk exists, alternatives to condom use for HIV prevention are needed. Currently there are several alternative bio-medical HIV-prevention products in different stages of development: microbicides, vaccines, post-exposure prophylaxis (PEP) and pre-exposure prophylaxis (PrEP). Seventy-two men who have sex with men (MSM) who took part in a study on Internet use and intentional condomless anal intercourse were asked about these four products during a semi-structured interview. The questions explored knowledge and acceptability of all the products and willingness to participate in microbicide and vaccine trials. Qualitative analysis of the data suggests that these men had virtually no knowledge of PrEP, very limited knowledge of microbicides, some information about PEP and considerably more knowledge about vaccines. Reactions towards the products were generally positive except for PrEP, for which reactions were polarized as either enthusiastic or negative. With the exception of PrEP, many men expressed willingness to use the products in the future. Most men would be willing to participate in trials for microbicides and vaccines if given basic reassurances. Concerns over negative side effects and preoccupation with possible infection were some of the motives given for non-willingness to participate in a vaccine trial. These results should inform the development of future trials of biomedical prevention products.

  13. Extension of biomass estimates to pre-assessment periods using density dependent surplus production approach.

    Directory of Open Access Journals (Sweden)

    Jan Horbowy

    Full Text Available Biomass reconstructions to pre-assessment periods for commercially important and exploitable fish species are important tools for understanding long-term processes and fluctuation on stock and ecosystem level. For some stocks only fisheries statistics and fishery dependent data are available, for periods before surveys were conducted. The methods for the backward extension of the analytical assessment of biomass for years for which only total catch volumes are available were developed and tested in this paper. Two of the approaches developed apply the concept of the surplus production rate (SPR, which is shown to be stock density dependent if stock dynamics is governed by classical stock-production models. The other approach used a modified form of the Schaefer production model that allows for backward biomass estimation. The performance of the methods was tested on the Arctic cod and North Sea herring stocks, for which analytical biomass estimates extend back to the late 1940s. Next, the methods were applied to extend biomass estimates of the North-east Atlantic mackerel from the 1970s (analytical biomass estimates available to the 1950s, for which only total catch volumes were available. For comparison with other methods which employs a constant SPR estimated as an average of the observed values, was also applied. The analyses showed that the performance of the methods is stock and data specific; the methods that work well for one stock may fail for the others. The constant SPR method is not recommended in those cases when the SPR is relatively high and the catch volumes in the reconstructed period are low.

  14. Development of Production Control in Small Batch Production

    Directory of Open Access Journals (Sweden)

    Németh Péter

    2016-01-01

    Full Text Available Our aim with this paper is to develop a new performance measurement and control system for small batch production in the automotive industry. For this reason, we present our previous research results for warehouse performance measurement and adopt its methodology to production control. The proposed method is based on artificial intelligence (neural networks.

  15. Product, Organizational and Performance Effects of Product Modularity

    DEFF Research Database (Denmark)

    Boer, Henrike Engele Elisabeth

    2014-01-01

    beyond these industries. To be able to establish whether firms not part of these industries would experience the same performance effects, survey research will be needed. To support future survey research, this paper proposes an operationalization of product modularity and details the link between...... product modularity and firm performance, to support the future development of measures and hypotheses....

  16. Is past academic productivity predictive of radiology resident academic productivity?

    Science.gov (United States)

    Patterson, Stephanie K; Fitzgerald, James T; Boyse, Tedric D; Cohan, Richard H

    2002-02-01

    The authors performed this study to determine whether academic productivity in college and medical school is predictive of the number of publications produced during radiology residency. The authors reviewed the records of 73 radiology residents who completed their residency from 1990 to 2000. Academic productivity during college, medical school, and radiology residency, other postgraduate degrees, and past careers other than radiology were tabulated. The personal essay attached to the residency application was reviewed for any stated academic interest. Residents were classified as being either previously productive or previously unproductive. Publication rates during residency and immediately after residency were compared for the two groups. For the productive residents, a correlation analysis was used to examine the relationship between past frequency of publication and type of previous activity. Least-squares regression analysis was used to investigate the relationship between preresidency academic productivity, advanced degrees, stated interest in academics, and other careers and radiology residency publications. There was no statistically significant difference in the number of articles published by those residents who were active and those who were not active before residency (P = .21). Only authorship of papers as an undergraduate was weakly predictive of residency publication. These selected measures of academic productivity as an undergraduate and during medical school are not helpful for predicting publication during residency. There was no difference in publication potential between those residents who were academically productive in the past and those who were not.

  17. A hydrogen production experiment by the thermo-chemical and electrolytic hybrid hydrogen production in lower temperature range. System viability and preliminary thermal efficiency estimation

    International Nuclear Information System (INIS)

    Takai, Toshihide; Nakagiri, Toshio; Inagaki, Yoshiyuki

    2008-10-01

    A new experimental apparatus by the thermo-chemical and electrolytic Hybrid-Hydrogen production in Lower Temperature range (HHLT) was developed and hydrogen production experiment was performed to confirm the system operability. Hydrogen production efficiency was estimated and technical problems were clarified through the experimental results. Stable operation of the SO 3 electrolysis cell and the sulfur dioxide solution electrolysis cell were confirmed during experimental operation and any damage which would be affected solid operation was not detected under post operation inspection. To improve hydrogen production efficiency, it was found that the reduction of sulfuric acid circulation and the decrease in the cell voltage were key issues. (author)

  18. Combinatorial Models for Assembly and Decomposition of Products

    OpenAIRE

    A. N. Bojko

    2015-01-01

    The paper discusses the most popular combinatorial models that are used for the synthesis of design solutions at the stage of the assembly process flow preparation. It shows that while assembling the product the relations of parts can be represented as a structure of preferences, which is formed on the basis of objective design restrictions put in at the stage of the product design. This structure is a binary preference relation pre-order. Its symmetrical part is equivalence and describes the...

  19. Nephrotoxicity of Natural Products.

    Science.gov (United States)

    Nauffal, Mary; Gabardi, Steven

    2016-01-01

    The manufacture and sale of natural products constitute a multi-billion dollar industry. Nearly a third of the American population admit to using some form of complementary or alternative medicine, with many using them in addition to prescription medications. Most patients fail to inform their healthcare providers of their natural product use and physicians rarely inquire. Annually, thousands of natural product-induced adverse events are reported to Poison Control Centers nationwide. Natural product manufacturers are not responsible for proving safety and efficacy, as the FDA does not regulate them. However, concerns exist surrounding the safety of natural products. This review provides details on natural products that have been associated with renal dysfunction. We have focused on products that have been associated with direct renal injury, immune-mediated nephrotoxicity, nephrolithiasis, rhabdomyolysis with acute renal injury, hepatorenal syndrome, and common adulterants or contaminants that are associated with renal dysfunction. The potential for natural products to cause renal dysfunction is justifiable. It is imperative that natural product use be monitored closely in all patients. Healthcare practitioners must play an active role in identifying patients using natural products and provide appropriate patient education. © 2016 S. Karger AG, Basel.

  20. The influence of animal fat replacement with vegetable oils on sensorial perception of meat emulsified products

    Directory of Open Access Journals (Sweden)

    Cristian TUDOSE

    2014-12-01

    Full Text Available For the purpose of the present study, in an emulsified meat product the pork backfat was replaced with a vegetable oil pre-emulsion and its effect on quality attributes were investigated. In order to do so, a classic and a new meat products were manufactured. Extra virgin olive oil and palm oil pre-emulsion were added instead of animal fat in the new product. Texture and physiochemical properties were analyzed by instrumental measurements. It was observed that during storage moisture and pH decreased. Using vegetable oils determined substantial increase of TBA values. Texture was influenced mainly by storage time for both products, while replacement of pork backfat with vegetable oil pre-emulsion had no influence on sample firmness. The sensory properties of meat products were evaluated by a group of trained panelists using an analitycal sensory evaluation technique. Overall the new product presented good acceptability which recommends it like a new healthier meat product.

  1. Dictionaries for text production

    DEFF Research Database (Denmark)

    Fuertes-Olivera, Pedro; Bergenholtz, Henning

    2018-01-01

    Dictionaries for Text Production are information tools that are designed and constructed for helping users to produce (i.e. encode) texts, both oral and written texts. These can be broadly divided into two groups: (a) specialized text production dictionaries, i.e., dictionaries that only offer...... a small amount of lexicographic data, most or all of which are typically used in a production situation, e.g. synonym dictionaries, grammar and spelling dictionaries, collocation dictionaries, concept dictionaries such as the Longman Language Activator, which is advertised as the World’s First Production...... Dictionary; (b) general text production dictionaries, i.e., dictionaries that offer all or most of the lexicographic data that are typically used in a production situation. A review of existing production dictionaries reveals that there are many specialized text production dictionaries but only a few general...

  2. Enabling local production of biopharmaceuticals in South Africa

    CSIR Research Space (South Africa)

    Tsekoa, Tsepo L

    2017-10-01

    Full Text Available - based pharmaceuticals. 9 Case study 1: Rabivir, new-generation rabies post-exposure prophylaxis 10 Case study 2: Microbial production of biosimilar CRM197 carrier protein • Problem/Need: Accessible and cost-competitive paediatric vaccines... • Prohibitively expensive pricing of protein reagent (CRM197) used in manufacture of conjugate vaccines for children (e.g. multivalent pneumococcal vaccine) • Solution: Fermentation-based production in recombinant E. coli • Stage: Proof of concept complete...

  3. SMART Product Innovation

    DEFF Research Database (Denmark)

    Cramer-Petersen, Claus L.; Ahmed-Kristensen, Saeema; Li, Xuemeng

    2016-01-01

    . The ambition of The Danish Industry Foundation and The Kata Foundation was to develop a method; a robust and specific approach to ensure that product innovation in Danish enterprises in practice would result in products of the highest quality, producible at lower costs and profitable at competitive prices...... products to our neighboring countries continues to suffer. The customers’ financial capacity has been reduced and cheaper products from Asia and other regions have found their way into our local markets. Competition is fierce – especially pricewise. This was the starting point for the SMART project...

  4. Sustainable hydrogen production

    Energy Technology Data Exchange (ETDEWEB)

    Block, D.L.; Linkous, C.; Muradov, N.

    1996-01-01

    This report describes the Sustainable Hydrogen Production research conducted at the Florida Solar Energy Center (FSEC) for the past year. The report presents the work done on the following four tasks: Task 1--production of hydrogen by photovoltaic-powered electrolysis; Task 2--solar photocatalytic hydrogen production from water using a dual-bed photosystem; Task 3--development of solid electrolytes for water electrolysis at intermediate temperatures; and Task 4--production of hydrogen by thermocatalytic cracking of natural gas. For each task, this report presents a summary, introduction/description of project, and results.

  5. The business end of health information technology. Can a fully integrated electronic health record increase provider productivity in a large community practice?

    Science.gov (United States)

    De Leon, Samantha; Connelly-Flores, Alison; Mostashari, Farzad; Shih, Sarah C

    2010-01-01

    Electronic health records (EHRs) are expected to transform and improve the way medicine is practiced. However, providers perceive many barriers toward implementing new health information technology. Specifically, they are most concerned about the potentially negative impact on their practice finances and productivity. This study compares the productivity of 75 providers at a large urban primary care practice from January 2005 to February 2009, before and after implementing an EHR system, using longitudinal mixed model analyses. While decreases in productivity were observed at the time the EHR system was implemented, most providers quickly recovered, showing increases in productivity per month shortly after EHR implementation. Overall, providers had significant productivity increases of 1.7% per month per provider from pre- to post-EHR adoption. The majority of the productivity gains occurred after the practice instituted a pay-for-performance program, enabled by the data capture of the EHRs. Coupled with pay-for-performance, EHRs can spur rapid gains in provider productivity.

  6. Banana production systems: identification of alternative systems for more sustainable production.

    Science.gov (United States)

    Bellamy, Angelina Sanderson

    2013-04-01

    Large-scale, monoculture production systems dependent on synthetic fertilizers and pesticides, increase yields, but are costly and have deleterious impacts on human health and the environment. This research investigates variations in banana production practices in Costa Rica, to identify alternative systems that combine high productivity and profitability, with reduced reliance on agrochemicals. Farm workers were observed during daily production activities; 39 banana producers and 8 extension workers/researchers were interviewed; and a review of field experiments conducted by the National Banana Corporation between 1997 and 2002 was made. Correspondence analysis showed that there is no structured variation in large-scale banana producers' practices, but two other banana production systems were identified: a small-scale organic system and a small-scale conventional coffee-banana intercropped system. Field-scale research may reveal ways that these practices can be scaled up to achieve a productive and profitable system producing high-quality export bananas with fewer or no pesticides.

  7. Probiotic fermented dairy products

    OpenAIRE

    Adnan Tamime; Rajka Božanić; Irena Rogelj

    2003-01-01

    Fermented dairy products are the most popular vehicle used in theindustry for the implantation of the probiotic microflora in humans. Therefore this paper provides an overview of new knowledge on probiotic fermented dairy products. It involves historical developments, commercial probiotic microorganisms and products, and their therapeutic properties, possibilities of quality improvement of different types of newly developed fermented dairy products together with fermented goat’s milk products.

  8. Measuring green productivity of country: A generlized metafrontier Malmquist productivity index approach

    International Nuclear Information System (INIS)

    Yu-Ying Lin, Eugene; Chen, Ping-Yu; Chen, Chi-Chung

    2013-01-01

    This paper measures environmental productivity in 70 countries over the period 1981–2007. Differences in green (environmental) productivity growth across countries under distinct country specific production frontier are measured using directional distance function model, which incorporates desirable output (GDP) and undesirable output (CO 2 emissions). The metafrontier which envelops the two country groups, developed countries and developing countries, are estimated using balanced panel data for the sample countries over the study period. A parametric method is used to compute technical efficiency change, technical change, and scale efficiency change, which aggregate to the generalized metafrontier Malmquist productivity index. The overall results indicated the two country groups operated under distinct stochastic production frontiers and therefore used different production technologies. It is found that developing countries achieved higher growth in their average environmental productivity relative to the metafrontier. Thus the results coincide with the convergence growth theory

  9. Resolving traceability issues of product derivation for software product lines

    OpenAIRE

    Abid, Saad bin

    2009-01-01

    peer-reviewed Dealing with traceability management issues during model based product derivation in large complex industrial SPL is error prone due to the lack of tool support. As a result traceability management between connected models emerges as an important research topic. In this position paper, we discuss research challenges as scenarios from developed example product line and give recommendations on resolving traceability issues during product derivation. We also discuss initial idea...

  10. Study of by-products of agro-food industries which could be used for bio-fuel production (animal fat, used food oils, and wine production by-products). Synthesis of the final report

    International Nuclear Information System (INIS)

    Gomy, Catherine; Thonier, Gregoire; Gagnepain, Bruno; Mhiri, Tarek

    2015-04-01

    As the Renewable Energy directive proposes the implementation of incentive arrangements for the production of bio-fuels from biomass, this report proposes a synthesis of a study which addressed three by-products of agro-food industry and of catering (collective, traditional, fast) which can help to reach objectives of energy production from biomass: used food oils, rendered animal fat of category 1 and 2, and vinification by-products (grape marc, lees, sludge). The objectives were to quantify, at the French national and regional levels, present resources and uses for these three by-products, non-valorised volumes and thus potentially available volumes for the production of liquid bio-fuels, to identify present actors and their interactions, and to study the potential of local production of liquid bio-fuels. The study comprised a comprehensive analysis of production and valorisation sectors for the three addressed types of by-products, and an identification of recent experiments implemented for the production of liquid bio-fuels. This synthesis states the lessons learned from the study of these three different sectors, and proposes recommendations for further developments

  11. Risperidone oral disintegrating mini-tablets: A robust-product for pediatrics.

    Science.gov (United States)

    El-Say, Khalid M; Ahmed, Tarek A; Abdelbary, Maged F; Ali, Bahaa E; Aljaeid, Bader M; Zidan, Ahmed S

    2015-12-01

    This study was aimed at developing risperidone oral disintegrating mini-tablets (OD-mini-tablets) as age-appropriate formulations and to assess their suitability for infants and pediatric use. An experimental Box-Behnken design was applied to assure high quality of the OD-mini-tablets and reduce product variability. The design was employed to understand the influence of the critical excipient combinations on the production of OD-mini-tablets and thus guarantee the feasibility of obtaining products with dosage form uniformity. The variables selected were mannitol percent in Avicel (X1), swelling pressure of the superdisintegrant (X2), and the surface area of Aerosil as a glidant (X3). Risperidone-excipient compatibilities were investigated using FTIR and the spectra did not display any interaction. Fifteen formulations were prepared and evaluated for pre- and post-compression characteristics. The prepared OD-mini-tablet batches were also assessed for disintegration in simulated salivary fluid (SSF, pH 6.2) and in reconstituted skimmed milk. The optimized formula fulfilled the requirements for crushing strength of 5 kN with minimal friability, disintegration times of 8.4 and 53.7 s in SSF and skimmed milk, respectively. This study therefore proposes the risperidone OD-mini-tablet formula having robust mechanical properties, uniform and precise dosing of medication with short disintegration time suitable for pediatric use.

  12. [Legislative regulation of production and turnover of products for people with different diseases].

    Science.gov (United States)

    Pritul'skaia, N V; Motuzka, Iu N; Antiushko, D L

    2013-01-01

    This article presents results of analysis of existing regulatory documents and approaches to the legislative regulation of production and turnover of special dietary products for people with specific diseases in EU, Ukraine and Russian Federation. According to the EU legislation, production and turnover of food products for nutritional support of people during specific diseases and the rehabilitation period are regulated by the Commission Directive 1999/21/EC, 2009/39/ES, by Regulation Commission (EU) No 953/2009 and documents of Codex Committee. Special food products for people with specific diseases in Ukrainian legislation are classified as nutrition products for special dietary use and are regulated by the following Laws of Ukraine "On the safety and quality of food", "On ensuring of sanitary and epidemiological welfare of the population", "On Consumer Rights Protection", "On advertising" and by other non-legislative acts. According to the current legislation of the Russian Federation, the products for people with specific diseases are classified as healthy dietary food products. The basis of the legal framework are federal laws "On the quality and safety of food", "On the sanitary-epidemiological welfare of the populations", "On technical regulations and technical regulations of the Customs Union "On Food Safety" and "On the safety of certain types of specialized food products, including healthy dietary food products and therapeutic dietary food products". There is no common approach to the legal regulation of production and turnover of products for people with specific diseases in the world. The proposals for further harmonization of regulatory control in this area have been developed.

  13. Strategy For A/M Area Production Wells

    International Nuclear Information System (INIS)

    Jackson, D.G.; Looney, B.B.; Bergren, C.L.; Wells, D.G.; Beavers, B.A.

    1996-01-01

    Savannah River Site personnel are planning a two phase program in order to significantly reduce the amount of dissolved chlorinated solvents that are being transported to the McQueen branch Aquifer via the wellbore and gravel pack zones of the A/M Area production well system. In Phase I of the program a commercially available inflatable packer and check valve assembly will be installed inside the casing at the altitude of the McQueen Branch Confining Unit. This immediate, short term solution will eliminate the majority of the contaminant mass that is moving downward through the wellbore of the A/M Area production wells. During the packer installation process several pre- and post- testing activities are planned to aid SRS investigators in understanding the dynamics of the flow conditions and effectiveness of the installed assembly.The second phase of the program will address the small amount of contaminant mass that is moving downward through the continuous gravel pack of the production wells. The investigative data obtained during Phase I of this program will be beneficial for developing plans and appropriate actions for the Phase II activities.In addressing potential remediation actions for the dissolved solvents in the Cretaceous sediments, due to the limited vertical extent of the plume and the size, any remediation program should incorporate carefully located wells screened vertically within the plume trajectory.This optimizing approach will minimize water treatment and pumping costs and maximize the amount of contaminant removal. Flow and contaminant transport modeling scenarios are currently being developed to address the Cretaceous sediments. These efforts involve incorporating the available characterization data and the results of previous modeling work to more precisely define the extent and magnitude of this plume. SRS proposes incorporating depth discrete sampling during any future characterization effort to optimize any proposed remediation system

  14. The availability of processed fruit products and their contents of ...

    African Journals Online (AJOL)

    fruit, poverty and post-harvest losses due to lack of skills for processing and storage. The objectives of this research were to survey household consumption of foods especially processed fruit products in Nairobi, and analyze nutritional quality of processed fruit products. Three estates representing different income groups ...

  15. Product derivation in software product families : a case study

    NARCIS (Netherlands)

    Deelstra, S; Sinnema, M; Bosch, J

    2005-01-01

    From our experience with several organizations that employ software product families, we have learned that, contrary to popular belief, deriving individual products from shared software assets is a time-consuming and expensive activity. In this paper we therefore present a study that investigated

  16. Supporting product-servicing networks

    NARCIS (Netherlands)

    Camarihna-Matos, L.M.; Ferrada, F.; Oliveira, A.I.; Afsarmanesh, H.; Aboutajdine, D.; Skalli, A.; Benchekroun, B.; Artiba, A.

    2013-01-01

    Service-based enhancement of products represents a growing trend, particularly in the context of complex products. A service-enhanced product can be seen as a market proposition that extends the traditional functionality of a product by incorporating additional business services, which not only

  17. Intelligent products : A survey

    NARCIS (Netherlands)

    Meyer, G.G.; Främling, K.; Holmström, J.

    This paper presents an overview of the field of Intelligent Products. As Intelligent Products have many facets, this paper is mainly focused on the concept behind Intelligent Products, the technical foundations, and the achievable practical goals of Intelligent Products. A novel classification of

  18. Making Product Customization Profitable

    DEFF Research Database (Denmark)

    Mortensen, Niels Henrik; Hvam, Lars; Haug, Anders

    2010-01-01

    The main result presented in this paper is the Framework for Product Family Master Plan. This framework supports the identification of a product architecture for companies that customize products and services. The framework has five coherent aspects, the market, product assortment, supply...

  19. Product Knowledge Modelling and Management

    DEFF Research Database (Denmark)

    Zhang, Y.; MacCallum, K. J.; Duffy, Alex

    1996-01-01

    function-oriented design. Both Specific Product Knowledge and Product Domain Knowledge are modelled at two levels, a meta-model and an information-level.Following that, a computer-based scheme to manage the proposed product lknowledge models within a dynamically changing environment is presented.......The term, Product Knowledge is used to refer to two related but distinct concepts; the knowledge of a specific product (Specific Product Knowledge) and the knowledge of a product domain (Product Domain Knowledge). Modelling and managing Product Knowlege is an essential part of carrying out design.......A scheme is presented in this paper to model, i.e. classify, structure and formalise the product knowledge for the purpose of supporting function-oriented design. The product design specification and four types of required attributes of a specific product have been identified to form the Specific Product...

  20. Multidisciplinary approach to successful implementation of production information system (PRISM)

    Energy Technology Data Exchange (ETDEWEB)

    Shariff, M.R.; Gopalakrishnan, S.G.; Francis, N. [and others

    1995-12-31

    A company wide corporate and regional production database supporting all production areas was envisaged critical to the current expansion within Petronas Carigali Sdn Bhd (PCSB). A multi disciplinary project team was thus formed to analyze the requirements prior to developing, testing, implementing and training users. PCSB has currently evolved into a mature E & P company on par with other E & P companies within the region. This expansion necessitates a common Production Information System for the efficient dissemination of vital Production Information for Production Surveillance, Reservoir Management, Reserve Assessment, Special Studies and Standardized Group-wide Reporting. This paper will discuss all the phases involved in the project which includes Systems Requirement Study, Data Migration, System Development, System Implementation and Post-Implementation Plan.

  1. Commercial production of metal hafnium and hafnium-based products

    International Nuclear Information System (INIS)

    Negodin, D.A.; Shtutsa, M.G.; Akhtonov, S.G.; Il'enko, E.V.; Kobyzev, A.M.

    2012-01-01

    Hafnium possesses a unique complex of physical and chemical properties which allow the application of products on its basis in various industries. Joint Stock Company 'Chepetsky Mechanical Plant' is the single enterprise which produces hafnium on the territory of Russia. The manufacture of metal hafnium with the total content of zirconium and hafnium, at least, 99,8 % of weights is developed at the present time at Joint Stock Company CHMZ. The weight of melted hafnium ingots is up to 1 ton. Manufacture of wide range of products from hafnium is implemented. The plates from a hafnium with thickness of 0.60 mm which are used for emergency control cartridges of VVER-440 reactors are the most critical product. It is shown that ingots and products obtained from metal hafnium correspond to the Russian and international standards for reactor materials in chemical composition, mechanical and corrosion properties.

  2. Pharmaceutical product development: A quality by design approach

    Science.gov (United States)

    Pramod, Kannissery; Tahir, M. Abu; Charoo, Naseem A.; Ansari, Shahid H.; Ali, Javed

    2016-01-01

    The application of quality by design (QbD) in pharmaceutical product development is now a thrust area for the regulatory authorities and the pharmaceutical industry. International Conference on Harmonization and United States Food and Drug Administration (USFDA) emphasized the principles and applications of QbD in pharmaceutical development in their guidance for the industry. QbD attributes are addressed in question-based review, developed by USFDA for chemistry, manufacturing, and controls section of abbreviated new drug applications. QbD principles, when implemented, lead to a successful product development, subsequent prompt regulatory approval, reduce exhaustive validation burden, and significantly reduce post-approval changes. The key elements of QbD viz., target product quality profile, critical quality attributes, risk assessments, design space, control strategy, product lifecycle management, and continual improvement are discussed to understand the performance of dosage forms within design space. Design of experiments, risk assessment tools, and process analytical technology are also discussed for their role in QbD. This review underlines the importance of QbD in inculcating science-based approach in pharmaceutical product development. PMID:27606256

  3. Pharmaceutical product development: A quality by design approach.

    Science.gov (United States)

    Pramod, Kannissery; Tahir, M Abu; Charoo, Naseem A; Ansari, Shahid H; Ali, Javed

    2016-01-01

    The application of quality by design (QbD) in pharmaceutical product development is now a thrust area for the regulatory authorities and the pharmaceutical industry. International Conference on Harmonization and United States Food and Drug Administration (USFDA) emphasized the principles and applications of QbD in pharmaceutical development in their guidance for the industry. QbD attributes are addressed in question-based review, developed by USFDA for chemistry, manufacturing, and controls section of abbreviated new drug applications. QbD principles, when implemented, lead to a successful product development, subsequent prompt regulatory approval, reduce exhaustive validation burden, and significantly reduce post-approval changes. The key elements of QbD viz., target product quality profile, critical quality attributes, risk assessments, design space, control strategy, product lifecycle management, and continual improvement are discussed to understand the performance of dosage forms within design space. Design of experiments, risk assessment tools, and process analytical technology are also discussed for their role in QbD. This review underlines the importance of QbD in inculcating science-based approach in pharmaceutical product development.

  4. Evidence supporting product standards for carcinogens in smokeless tobacco products.

    Science.gov (United States)

    Hatsukami, Dorothy K; Stepanov, Irina; Severson, Herb; Jensen, Joni A; Lindgren, Bruce R; Horn, Kimberly; Khariwala, Samir S; Martin, Julia; Carmella, Steven G; Murphy, Sharon E; Hecht, Stephen S

    2015-01-01

    Smokeless tobacco products sold in the United States vary significantly in yields of nicotine and tobacco-specific nitrosamines (TSNA). With the passage of the Family Smoking Prevention and Tobacco Control Act, the Food and Drug Administration now has the authority to establish product standards. However, limited data exist determining the relative roles of pattern of smokeless tobacco use versus constituent levels in the smokeless tobacco product in exposure of users to carcinogens. In this study, smokeless tobacco users of brands varying in nicotine and TSNA content were recruited from three different regions in the U.S. Participants underwent two assessment sessions. During these sessions, demographic and smokeless tobacco use history information along with urine samples to assess biomarkers of exposure and effect were collected. During the time between data collection, smokeless tobacco users recorded the amount and duration of smokeless tobacco use on a daily basis using their diary cards. Results showed that independent of pattern of smokeless tobacco use and nicotine yields, levels of TSNA in smokeless tobacco products played a significant role in carcinogen exposure levels. Product standards for reducing levels of TSNA in smokeless tobacco products are necessary to decrease exposure to these toxicants and potentially to reduce risk for cancer. ©2014 American Association for Cancer Research.

  5. Side-stream products of edible oil refining as feedstocks in biodiesel production

    Directory of Open Access Journals (Sweden)

    Cvetković Bojan S.

    2016-01-01

    Full Text Available Biodiesel, a diesel fuel alternative, is produced from vegetable oils and animal fats by the transesterification reaction of triacylglycerols and lower aliphatic alcohols. Beside number advantages related to fossil fuels, the main barrier to biodiesel wider commercial use is the high price of edible oils. Recently, the special attention was given to side-stream products of edible oil refining as low-cost triacylglycerol sources for biodiesel production because of their positive economic and ecological effects. In this paper, the different procedures for biodiesel production from side-stream refining products such as soapstock, spent bleaching earth and deodorizer distillate were analyzed. The main goal of this paper is to analyze the possibilities for reusing the by-products of edible oil refinement in the biodiesel production.

  6. The Potential of Animal By-Products in Food Systems: Production, Prospects and Challenges

    Directory of Open Access Journals (Sweden)

    Babatunde O. Alao

    2017-06-01

    Full Text Available The consumption of animal by-products has continued to witness tremendous growth over the last decade. This is due to its potential to combat protein malnutrition and food insecurity in many countries. Shortly after slaughter, animal by-products are separated into edible or inedible parts. The edible part accounts for 55% of the production while the remaining part is regarded as inedible by-products (IEBPs. These IEBPs can be re-processed into sustainable products for agricultural and industrial uses. The efficient utilization of animal by-products can alleviate the prevailing cost and scarcity of feed materials, which have high competition between animals and humans. This will also aid in reducing environmental pollution in the society. In this regard, proper utilization of animal by-products such as rumen digesta can result in cheaper feed, reduction in competition and lower cost of production. Over the years, the utilization of animal by-products such as rumen digesta as feed in livestock feed has been successfully carried out without any adverse effect on the animals. However, there are emerging gaps that need to be further addressed regarding the food security and sustainability of the products. Therefore, the objective of this review highlights the efficacy and effectiveness of using animal by-products as alternative sources of feed ingredients, and the constraints associated with their production to boost livestock performance in the industry at large.

  7. Product Seeding: Word-of-Mouth Effects For and Beyond the Focal Product

    Directory of Open Access Journals (Sweden)

    Bart Yakov

    2017-11-01

    Full Text Available In a classic seeded WOM marketing campaign, a company sends product samples to a selected group of influencers, and encourages them share the product information and their own opinions with other consumers. Positive effects include more WOM for the focal product in the target segment, but also in additional segments. But there are additional spillover effects on the brand and the product category level and they are negative. More conversations about the focal product reduced the “off-topic” conversations about other brands in the same category as well as other products of the same brand. These negative brand and category spillover effects are stronger when the focal product is of a more functional nature. Marketers tend to consider only positive spillovers to be beneficial for a company, but negative spillovers should not be immediately classified as “bad news.” There are upsides to this effect that managers can use in their favor.

  8. Grain dust induces IL-8 production from bronchial epithelial cells: the effect of dexamethasone on IL-8 production.

    Science.gov (United States)

    Park, H S; Suh, J H; Kim, H Y; Kwon, O J; Choi, D C

    1999-04-01

    Recent publications have suggested an active participation of neutrophils to induce bronchoconstriction after inhalation of grain dust (GD). To further understand the role of neutrophils in the pathogenesis of GD-induced asthma, this investigation was designed to determine whether human bronchial epithelial cells could produce IL-8 production and to observe the effect of dexamethasone on IL-8 production. We cultured Beas-2B, a bronchial epithelial cell line. To observe GD-induced responses, four concentrations (1 to 200 microg/mL) of GD were incubated for 24 hours and compared with those without incubation of GD. To evaluate the effect of pro-inflammatory cytokines on IL-8 production, epithelial cells were incubated with peripheral blood mononuclear cell (PBMC) culture supernatant, which was derived from the culture of PBMC from a GD-induced asthmatic subject under the exposure to 10 microg/mL of GD, and compared with those cultured without addition of PBMC supernatant. The level of released IL-8 in the supernatant was measured by enzyme-linked immunosorbent assay. To evaluate the effect of dexamethasone on IL-8 production, four concentrations (5 to 5000 ng/mL) of dexamethasone were pre-incubated for 24 hours and the same experiments were repeated. There was significant production of IL-8 from bronchial epithelial cells with additions of GD in a dose-dependent manner (P < .05), which was significantly augmented with additions of PBMC supernatant (P < .05) at each concentration. Compared with the untreated sample, pretreatment of dexamethasone could induced a remarkable inhibitions (15% to 55%) of IL-8 production from bronchial epithelial cells in a dose-dependent manner. These results suggest that IL-8 production from bronchial epithelial cells may contribute to neutrophil recruitment occurring in GD-induced airway inflammation. The downregulation of IL-8 production by dexamethasone from bronchial epithelial cells may contribute to the efficacy of this compound in

  9. Influence of dispatching rules on average production lead time for multi-stage production systems.

    Science.gov (United States)

    Hübl, Alexander; Jodlbauer, Herbert; Altendorfer, Klaus

    2013-08-01

    In this paper the influence of different dispatching rules on the average production lead time is investigated. Two theorems based on covariance between processing time and production lead time are formulated and proved theoretically. Theorem 1 links the average production lead time to the "processing time weighted production lead time" for the multi-stage production systems analytically. The influence of different dispatching rules on average lead time, which is well known from simulation and empirical studies, can be proved theoretically in Theorem 2 for a single stage production system. A simulation study is conducted to gain more insight into the influence of dispatching rules on average production lead time in a multi-stage production system. We find that the "processing time weighted average production lead time" for a multi-stage production system is not invariant of the applied dispatching rule and can be used as a dispatching rule independent indicator for single-stage production systems.

  10. Phase distribution of products of radiation and post-radiation distillation of biopolymers: Cellulose, lignin and chitin

    International Nuclear Information System (INIS)

    Ponomarev, A.V.; Kholodkova, E.M.; Metreveli, A.K.; Metreveli, P.K.; Erasov, V.S.; Bludenko, A.V.; Chulkov, V.N.

    2011-01-01

    Influence of both the absorbed dose and the dose rate of 8 MeV electron-beam radiation on destruction of microcrystalline cellulose, pine lignin and krill chitin was investigated. Two conversion modes were compared: (1) post-radiation distillation PRD and (2) electron-beam distillation EBD. Cellulose, chitin and lignin demonstrate different responses to irradiation and distillation in PRD and EBD modes. Treatment in EBD mode transforms biopolymers to organic liquid more productively than conventional dry distillation and treatment in PRD mode. Both radiation heating and an irradiation without heating intensify chitin and cellulose decomposition and distillation. At the same time lignin decaying rather efficiently in EBD mode appears to be insensitive to a preliminary irradiation in PRD mode up to a dose of 2.4 MGy. - Highlights: → Direct conversion of cellulose, chitin and lignin to organic liquid is intensified by electron-beam irradiation. → Alternative approach to bio-oil production. → Both electron-beam distillation mode and post-radiation distillation mode are effective for cellulose and chitin conversion. → Electron-beam distillation mode is preferable for lignin conversion. → Preliminary deep dehydration of biopolymers is realizable at low dose rates.

  11. Animal Production and Health Newsletter, No. 57, January 2013

    International Nuclear Information System (INIS)

    2013-01-01

    The 2012 Scientific Forum examined the challenges related to the improvement of food production, food protection and food safety through the use of nuclear applications. In the first session on 'Increasing Food Production' it was noted that the world will need to produce 70% more food between now and 2050 to satisfy the demand of a population in excess of 9 billion people. In this regard, the intensification and diversification of more and higher quality food in a climate-smart and sustainable manner whilst protecting the environment is therefore critical to smallholder farmers and is the key to poverty reduction and increased food security. The Forum noted that the increasing global population faces the challenge of substantially increasing food production under conditions of severe land degradation that has led to a significant reduction in the productive capacity of agricultural lands. Sustainable soil management, plant mutation breeding and animal nutrition and production are therefore critical to the improvement of agricultural productivity. The second session on 'Ensuring Food Protection' noted that global food insecurity is inherently linked to pests and diseases that harm or kill livestock and crops, as well as people working in rural agricultural areas. The losses caused by diseases and pests at both the pre- and post-harvest levels average 30-40% of agricultural outputs, making returns on agricultural investments in land, seeds, water, fertilizer, animal feed, labour and other inputs correspondingly inefficient. In addition, the world is currently facing an unprecedented increase of invasive animal and plant diseases and pests that threaten food security by causing serious losses in production and by necessitating costly control measures, including the escalating use of increasingly expensive pesticides. Outbreaks of secondary pests, the development of resistance of pests to pesticides and the increasing threat of zoonotic diseases to public health cause

  12. Village poultry production in Madagascar: Production characteristics and epidemiology

    International Nuclear Information System (INIS)

    Koko, M.; Maminiaina, O.F.; Ravaomanana, J.; Rakotonindrina, S.J.

    2002-01-01

    In order to investigate the production characteristics of village poultry in Madagascar, a cross sectional survey was done in May, 1999 in zone 1 and in June 1999 in zone 2. Furthermore, a longitudinal survey was done in 33 farms in the two zones during a 12 month period providing information on flock dynamics and causes of mortality. The indigenous chicken in Madagascar represents 91% of the total poultry population. Each farm has on average 11 birds, which survive by scavenging. The average productivity is 33.3 eggs/hen/year and 2.76 clutches/hen/year. The average hatchability is 77.8% and 75% of the eggs are used for renewing the flock. Mortality figures are very high: 42.3% of the chicks die before weaning and 34.5% of the growers die before becoming adults. Mortality of adults is on average 3 1.4%. Mortality is due to various factors, but is mainly due to internal parasites in the chicks (38.5%), especially during the dry season. Newcastle disease (ND) is the most important infectious cause of mortality causing more than 68.8% of the deaths in growers and 75% in the adults. Post mortem results confirmed serological information using the indirect haemagglutination test indicating the importance of ND. However, further study is necessary to identify the wild strains of ND that might circulate in Madagascar. (author) [fr

  13. The Effects of Pre-Task, On-Line, and Both Pre-Task and On-Line Planning on Fluency, Complexity, and Accuracy--The Case of Iranian EFL Learners' Written Production

    Science.gov (United States)

    Piri, Faramarz; Barati, Hossein; Ketabi, Saeed

    2012-01-01

    Previous studies on the effect of planning on language production have revealed that planning does have a positive effect on language performance in terms of fluency, complexity, and accuracy. The present study was an attempt to investigate the effects of pre-task, on-line, and both pre-task and on-line planning on fluency, accuracy, and…

  14. Confronting product life thinking with product life cycle analysis

    DEFF Research Database (Denmark)

    McAloone, Tim C.

    2001-01-01

    to "read" the environment out of the product, in order to systematically, quickly and efficiently come to some design recommendations for the company. The phrases "LCA" and "product life thinking" will be described and differentiated and a pattern identified for their cooperative effect in use....

  15. Product- and Process Units in the CRITT Translation Process Research Database

    DEFF Research Database (Denmark)

    Carl, Michael

    than 300 hours of text production. The database provides the raw logging data, as well as Tables of pre-processed product- and processing units. The TPR-DB includes various types of simple and composed product and process units that are intended to support the analysis and modelling of human text......The first version of the "Translation Process Research Database" (TPR DB v1.0) was released In August 2012, containing logging data of more than 400 translation and text production sessions. The current version of the TPR DB, (v1.4), contains data from more than 940 sessions, which represents more...

  16. Data sheets of fission product release experiments for light water reactor fuel, (2)

    International Nuclear Information System (INIS)

    Ishiwatari, Nasumi; Nagai, Hitoshi; Takeda, Tsuneo; Yamamoto, Katsumune; Nakazaki, Chozaburo.

    1979-07-01

    This is the second data sheets of fission products (FP) release experiments for light water reactor fuel. Results of five FP release experiments from the third to the seventh are presented: results of pre-examinations of UO 2 pellets, photographs of parts of fuel rod assemblies for irradiation and the assemblies, operational conditions of JMTR and OWL-1, variations of radioiodine-131 level in the main loop coolant during experimental periods, and representative results of post-irradiation examinations of respective fuel rods. (author)

  17. Software product quality measurement

    OpenAIRE

    Godliauskas, Eimantas

    2016-01-01

    This paper analyses Ruby product quality measures, suggesting three new measures for Ruby product quality measurement tool Rubocop to measure Ruby product quality characteristics defined in ISO 2502n standard series. This paper consists of four main chapters. The first chapter gives a brief view of software product quality and software product quality measurement. The second chapter analyses object oriented quality measures. The third chapter gives a brief view of the most popular Ruby qualit...

  18. Play as productionproduction as game?

    DEFF Research Database (Denmark)

    Eichberg, Henning

    2015-01-01

    Play-related products and their export have through recent decades contributed to a certain Danish image on the world level – with Lego bricks at the commercial end and adventure playgrounds at the pedagogical end. The phenomena of toy production and play exports challenge our understanding of what...... “play” and “game” are, and of their social as well as political significance. At the municipal level, the city of Odense – “city of Hans Christian Andersen” – is branding itself as “city of play”. On the international level, Danish play-related products have expanded on the world market. In the field...... of sport, Danish sport is not just elite sport, but also organized in local associations. People meet in mass summer festivals of popular sport. Folk Academies develop sport as personal development, often in an experimental way. Street sports, parkour, play and games are promoted. Civil society is a basis...

  19. A guide for controlling consumer products containing radioactive substances

    International Nuclear Information System (INIS)

    1985-01-01

    Consumer products are considered regardless of the purpose for which the radionuclide is added. For example, the purpose may be to make use of the ionising radiation emitted by the substance in the product itself (e.g. radioluminescent devices antistatic devices and ionisation chamber smoke detectors), or to make use of some other property of the material where the presence of radiation in the final product is merely adventitious (e.g. thorium gas mantles, ceramics with uranium glazes, and products containing radioactive tracers added to facilitate manufacturing and inspection processes). The Guide does not cover some products containing natural radioactive substances which have not been intentionally added, such as building materials. The Guide does not cover medicinal products and pharmaceuticals, nuclear powered cardiac pacemakers, or electronic equipment, such as television receivers, that emit X-rays. Unlike the 1970 Guide, this Guide does not consider those products, such as EXIT signs, containing gaseous tritium light sources, that would not be supplied directly to members of the public. The Guide is concerned mainly with the exposure arising from consumer products of those persons who are not subject to any regulatory controls for purposes of radiation protection in normal circumstances. Members of the public come under this heading, but not workers involved in the manufacture of consumer products. These workers will normally be subject to separate control. Radiological protection concepts and policy for the control of radioactive consumer products and licensing and post-licensing surveillance are developed

  20. Animal Production Research Advances

    African Journals Online (AJOL)

    Animal Production Research Advances is a peer-review journal established expressly to promote the production of all animal species utilized as food. The journal has an international scope and is intended for professionals in animal production and related sciences. We solicit contributions from animal production and ...

  1. Accounting for productivity

    DEFF Research Database (Denmark)

    Aiyar, Shekhar; Dalgaard, Carl-Johan Lars

    2009-01-01

    The development accounting literature almost always assumes a Cobb-Douglas (CD) production function. However, if in reality the elasticity of substitution between capital and labor deviates substantially from 1, the assumption is invalid, potentially casting doubt on the commonly held view...... that factors of production are relatively unimportant in accounting for differences in labor productivity. We use international data on relative factor shares and capital-output ratios to formulate a number of tests for the validity of the CD assumption. We find that the CD specification performs reasonably...... well for the purposes of cross-country productivity accounting....

  2. Measuring Clinical Productivity.

    Science.gov (United States)

    Hudson, Mark E; Lebovitz, Evan E

    2018-06-01

    Productivity measurements have been used to evaluate and compare physicians and physician practices. Anesthesiology is unique in that factors outside anesthesiologist control impact opportunity for revenue generation and make comparisons between providers and facilities challenging. This article uses data from the multicenter University of Pittsburgh Physicians Department of Anesthesiology to demonstrate factors influencing productivity opportunity by surgical facility, between department divisions and subspecialties within multispecialty divisions, and by individuals within divisions. The complexities of benchmarking anesthesiology productivity are demonstrated, and the potential value of creating a productivity profile for facilities and groups is illustrated. Copyright © 2018 Elsevier Inc. All rights reserved.

  3. Smokeless tobacco products harbor diverse bacterial microbiota that differ across products and brands.

    Science.gov (United States)

    Smyth, Eoghan M; Kulkarni, Prachi; Claye, Emma; Stanfill, Stephen; Tyx, Robert; Maddox, Cynthia; Mongodin, Emmanuel F; Sapkota, Amy R

    2017-07-01

    Smokeless tobacco products contain numerous chemical compounds, including known human carcinogens. Other smokeless tobacco constituents, including bacteria, may also contribute to adverse health effects among smokeless tobacco users. However, there is a lack of data regarding the microbial constituents of smokeless tobacco. Our goal was to characterize the bacterial microbiota of different smokeless tobacco products and evaluate differences across product types and brands. DNA was extracted from 15 brands of smokeless tobacco products (including dry snuff, moist snuff, snus, and Swedish snus) and 6 handmade products (e.g., toombak) using an enzymatic and mechanical lysis approach. Bacterial community profiling was performed using PCR amplification of the V1-V2 hypervariable region of the 16S rRNA gene, followed by 454 pyrosequencing of the resulting amplicons and sequence analysis using the QIIME package. Total viable counts were also determined to estimate the number of viable bacteria present in each product. Average total viable counts ranged from 0 to 9.35 × 10 7  CFU g -1 . Analysis of the 16S rRNA gene sequences revealed high bacterial diversity across the majority of products tested: dry snuff products where characterized by the highest diversity indices compared to other products. The most dominant bacterial phyla across all products were Firmicutes, Proteobacteria, Actinobacteria, and Bacteroidetes. Significant differences in both bacterial community composition and in silico predicted gene content were observed between smokeless tobacco product types and between brands of specific smokeless tobacco products. These data are useful in order to comprehensively address potential health risks associated with the use of smokeless tobacco products.

  4. Enhancement of Plant Productivity in the Post-Genomics Era.

    Science.gov (United States)

    Thao, Nguyen Phuong; Tran, Lam-Son Phan

    2016-08-01

    in mediating cellular ion homeostasis and plant tolerance to both biotic and abiotic stresses. In summary, with recent progresses in biological and biotechnological areas, especially rapid development of advanced technologies in biological system modeling, functional genomics, computer-based analyzing tools, genetic engineering and molecular breeding, biological control and biotechnological applications in agriculture have brought about an extraordinary revolution and have been considered the most powerful approaches in maintaining or even increasing crop yield. Therefore, in this issue, we would like to introduce to the audience a collection of various strategies used for enhancing crop productivity, with the focus on advanced biological-biotechnological platforms in the post-genomics era.

  5. Perfusion seed cultures improve biopharmaceutical fed-batch production capacity and product quality.

    Science.gov (United States)

    Yang, William C; Lu, Jiuyi; Kwiatkowski, Chris; Yuan, Hang; Kshirsagar, Rashmi; Ryll, Thomas; Huang, Yao-Ming

    2014-01-01

    Volumetric productivity and product quality are two key performance indicators for any biopharmaceutical cell culture process. In this work, we showed proof-of-concept for improving both through the use of alternating tangential flow perfusion seed cultures coupled with high-seed fed-batch production cultures. First, we optimized the perfusion N-1 stage, the seed train bioreactor stage immediately prior to the production bioreactor stage, to minimize the consumption of perfusion media for one CHO cell line and then successfully applied the optimized perfusion process to a different CHO cell line. Exponential growth was observed throughout the N-1 duration, reaching >40 × 10(6) vc/mL at the end of the perfusion N-1 stage. The cultures were subsequently split into high-seed (10 × 10(6) vc/mL) fed-batch production cultures. This strategy significantly shortened the culture duration. The high-seed fed-batch production processes for cell lines A and B reached 5 g/L titer in 12 days, while their respective low-seed processes reached the same titer in 17 days. The shortened production culture duration potentially generates a 30% increase in manufacturing capacity while yielding comparable product quality. When perfusion N-1 and high-seed fed-batch production were applied to cell line C, higher levels of the active protein were obtained, compared to the low-seed process. This, combined with correspondingly lower levels of the inactive species, can enhance the overall process yield for the active species. Using three different CHO cell lines, we showed that perfusion seed cultures can optimize capacity utilization and improve process efficiency by increasing volumetric productivity while maintaining or improving product quality. © 2014 American Institute of Chemical Engineers.

  6. Integrating Molecular Computation and Material Production in an Artificial Subcellular Matrix

    DEFF Research Database (Denmark)

    Fellermann, Harold; Hadorn, Maik; Bönzli, Eva

    Living systems are unique in that they integrate molecular recognition and information processing with material production on the molecular scale. Pre- dominant locus of this integration is the cellular matrix, where a multitude of biochemical reactions proceed simultaneously in highly compartmen......Living systems are unique in that they integrate molecular recognition and information processing with material production on the molecular scale. Pre- dominant locus of this integration is the cellular matrix, where a multitude of biochemical reactions proceed simultaneously in highly...... compartmentalized re- action compartments that interact and get delivered through vesicle trafficking. The European Commission funded project MatchIT (Matrix for Chemical IT) aims at creating an artificial cellular matrix that seamlessly integrates infor- mation processing and material production in much the same...

  7. Financial results achieved in short-day strawberry production

    Directory of Open Access Journals (Sweden)

    Galić Dragan

    2014-01-01

    Full Text Available In South-western Ontario's continental climate (short days, hot summers and very cold winters the matted-row system was the dominant production system to grow short-day strawberries. Varieties-staggered production (planting a combination of early, mid and late-season varieties provides strawberry harvest from five to seven weeks. Short-day strawberries are vegetative grown in the first year, and harvested for two consecutive years. The total cost of short-day strawberry production was 54,370 $CAD/ha. The production and harvest costs in the first and second years were 20,812 $CAD/ha and 16,930 $CAD/ ha, respectively, and accounted for 69.42% of the total. Pre-plans operations were the least expensive procedures costing 8.13%, while planting and care of young plants made up 22.45% of the total costs. The total income of growing short-day strawberries under a matted-row system was 76,671 $CAD/ha (the first and second production years 41,330 $CAD/ha and 35,341 $CAD/ha, respectively. The short-day strawberries in matted-row system, with average yield of 15,722 kg/ha, generated a net revenue of 22,300 $CAD/ha.

  8. Impact of product configuration systems on product profitability and costing accuracy

    DEFF Research Database (Denmark)

    Myrodia, Anna; Kristjansdottir, Katrin; Hvam, Lars

    2017-01-01

    in control of their product assortment, making the right decisions in the sales phase and increasing sales of optimal products. These benefits should have an impact on the company's ability to make more accurate cost estimations in the sales phase, which can positively affect the products’ profitability......This article aims at analyzing the impact of implementing a product configuration system (PCS) on the increased accuracy of the cost calculations and the increased profitability of the products. Companies that have implemented PCSs have achieved substantial benefits in terms of being more...... and after a PCS was implemented. The comparison in the case study revealed that increased accuracy of the cost calculations in the sales phase and consequently increased profitability can be achieved by implementing a PCS....

  9. Device to irradiate agricultural product on the production site, after harvesting

    International Nuclear Information System (INIS)

    Jegu, Jean; Palomo, Georges; Blaive, Daniel.

    1982-01-01

    The invention concerns a device to irradiate agricultural product on the production site, after harvesting. It includes an outer shielding to absorb the radiations and containers in which the products are placed for irradiation. The shielding is rotationally symmetrical around a vertical axis and holds an irradiation chamber containing a radioactive bar fitted along the shielding axis. The cylindrical containers are placed around the chamber with their axes parallel to the axis of the shielding. They are set in rotation by a motor and receive the farm products through their top ends which communicate with a supply system. Their bottom ends are closed by shutters covering a means for evacuating the products. The invention applies in particular to the irradiation of newly dug potatoes to avoid germination [fr

  10. Modelling of virtual production networks

    Directory of Open Access Journals (Sweden)

    2011-03-01

    Full Text Available Nowadays many companies, especially small and medium-sized enterprises (SMEs, specialize in a limited field of production. It requires forming virtual production networks of cooperating enterprises to manufacture better, faster and cheaper. Apart from that, some production orders cannot be realized, because there is not a company of sufficient production potential. In this case the virtual production networks of cooperating companies can realize these production orders. These networks have larger production capacity and many different resources. Therefore it can realize many more production orders together than each of them separately. Such organization allows for executing high quality product. The maintenance costs of production capacity and used resources are not so high. In this paper a methodology of rapid prototyping of virtual production networks is proposed. It allows to execute production orders on time considered existing logistic constraints.

  11. Antiproton production

    International Nuclear Information System (INIS)

    Allaby, J.V.

    1984-01-01

    The basic definitions used in the physics literature on particle production are reviewed. The data on anti p production are interpreted in order to provide an estimate of the yield of anti p's from typical target at the antiproton accumulator, including the effects of re-absorption in the target. (orig.)

  12. Chlorhexidine in cosmetic products

    DEFF Research Database (Denmark)

    Opstrup, Morten Schjørring; Johansen, Jeanne Duus; Bossi, Rossana

    2015-01-01

    or an antimicrobial agent in cosmetic products at a concentration up to 0.3%, as set by the European Cosmetics Directive (now Regulations). OBJECTIVES: To identify cosmetic product types containing chlorhexidine, and to measure the concentration of chlorhexidine in selected products. METHODS: Between February 2013...... and April 2013, we checked for chlorhexidine in cosmetic products in 14 supermarkets, one hairdressing salon and one beauty and retail store in Copenhagen, Denmark by reading the ingredient labels. The chlorhexidine concentration was measured in 10 selected products by high-performance liquid chromatography...... concentrations were 0.01-0.15%. CONCLUSIONS: We found chlorhexidine in various cosmetic product types, predominantly aimed at females, and in hair products. The measured chlorhexidine concentrations were all within the permitted limit. The relevance for allergic sensitization should be further explored....

  13. Impact of product platforms on lean production systems : evidence from industrial machinery manufacturing

    NARCIS (Netherlands)

    Alblas, A.A.; Wortmann, J.C.

    2012-01-01

    The present study describes the effects of product platform changes on lean production systems. Current research into product platforms focuses mostly on the development stage. However, although the initial development of platforms is an important issue, product platforms often evolve during later

  14. Alignment of Product Models and Product State Models - Integration of the Product Lifecycle Phases

    DEFF Research Database (Denmark)

    Larsen, Michael Holm; Kirkby, Lars Phillip; Vesterager, Johan

    1999-01-01

    The purpose of this paper is to discuss the integration of the Product Model (PM) and the Product State Model (PCM). Focus is on information exchange from the PSM to the PM within the manufacturing of a single ship. The paper distinguishes between information and knowledge integration. The paper ...... provides some overall strategies for integrating PM and PSM. The context of this discussion is a development project at Odense Steel Shipyard....

  15. From Sentence Production to Text Production: Investigating Fundamental Processes.

    Science.gov (United States)

    Fayol, Michel

    1991-01-01

    Presents a review of cognitive psychology research dealing with the organization and functioning of oral and written language production mechanisms. Discusses works dealing with the microstructural aspects of language, primarily oral production. Describes how the research perspective has evolved from modular to connectionist models. Examines the…

  16. Production and Productivity Effects of Informal Contract Farming in ...

    African Journals Online (AJOL)

    This paper uses data from a 2001 household survey of small-scale farming households in Kirinyaga District, Kenya to explore production effects of informal credit contracts in French bean farming where formal markets for surplus production are seemingly shallow and imperfect. Specifically, it examines whether informal ...

  17. Effect of timing and type of supplementary grain on herbage intake, nitrogen utilization and milk production in dairy cows grazed on perennial ryegrass pasture from evening to morning.

    Science.gov (United States)

    Ueda, Koichiro; Mitani, Tomohiro; Kondo, Seiji

    2017-01-01

    The present study aimed to clarify the effect of timing and type of supplementary grain in grazing dairy cows on herbage dry matter intake (HDMI), nitrogen utilization and milk production. Eight lactating cows were allowed to graze from evening to morning during three seasonal periods (spring, summer, autumn). They were randomly allocated to four treatments (timing: pre- (Pre) or post-grazing (Post), for large grain allotments consisting of 75% of daily grain offered; grain type: barley or corn) in 4 × 4 Latin square designs in each period. In the spring period, HDMI was greater for cows fed corn than those fed barley (P = 0.005), whereas cows in the Pre treatment had a similar HDMI, higher (P = 0.049) urinary purine derivative concentration and greater (P = 0.004) milk yield compared with cows in the Post treatment. In the summer and autumn periods, timing treatments did not affect HDMI, nitrogen utilization or milk production, but cows supplemented with barley had higher urinary purine derivatives concentration (P production without reducing HDMI regardless of grain type. © 2016 Japanese Society of Animal Science.

  18. Product sounds : Fundamentals and application

    NARCIS (Netherlands)

    Ozcan-Vieira, E.

    2008-01-01

    Products are ubiquitous, so are the sounds emitted by products. Product sounds influence our reasoning, emotional state, purchase decisions, preference, and expectations regarding the product and the product's performance. Thus, auditory experience elicited by product sounds may not be just about

  19. 75 FR 33814 - Tobacco Product Constituents Subcommittee of the Tobacco Products Scientific Advisory Committee...

    Science.gov (United States)

    2010-06-15

    ...] Tobacco Product Constituents Subcommittee of the Tobacco Products Scientific Advisory Committee; Notice of... to the public. Name of Committee: Tobacco Product Constituents Subcommittee of the Tobacco Products...-8900. Contact Person: Karen Templeton-Somers, Office of Science, Center for Tobacco Products, Food and...

  20. K-shell-hole production, multiple-hole production, charge transfer, and antisymmetry

    International Nuclear Information System (INIS)

    Reading, J.F.; Ford, A.L.

    1980-01-01

    In calculating K-shell-hole production when an ion collides with an atom, account must be taken of the fact that processes involving electrons other than the K-shell electron can occur. For example, after making a K-shell hole an L-shell electron may be knocked into it, or an L-shell vacancy may be produced and the K-shell electron promoted to that vacancy in the ''Fermi sea'' of the target-atom orbitals. In 1973 a theorem was proved by one of the present authors demonstrating that all these multielectron processes cancel in an independent-particle model for the target atom. In this paper it is shown that the same thing occurs for hole production by charge transfer to the ion. The authors demonstrate that multihole production does not obey this simple rule and that the probability for multihole production is not the product of independent single-electron probabilities. The correct expressions that should be used for these processes are given, together with new results for charge-transfer processes accompanied by hole production